Agenda

Not Applicable

Day 1: Wednesday, February 25, 2015	Slides Approved for Dissemination
*Slides presented at the meeting which have been approved for public posting are provided below. In addition, breaks for coffee and lunch have been removed from the agenda.*
8:00 - 8:30 a.m. --- Opening Remarks
Welcome from the NIH Common Fund and SPARC Dr. James M. Anderson – Director, NIH, OD/DPCPSI Dr. Roderic Pettigrew – Director, NIH, NIBIB Introducing the SPARC Program Dr. Alan Willard – Acting Deputy Director, NIH, NINDS Charge for the SPARC Workshop Dr. Gregory Germino – Deputy Director, NIH, NIDDK	Slides are not available
8:30 - 9:30 a.m. --- Overviews --- Session Chair: Dr. Terry Powley
Overview of Current Approaches Dr. Kip Ludwig – NIH, NINDS (20 min)
Challenges in Neuromodulation Therapy Dr. Milton Morris – MEH BioMedical, LLC (20 min)
Overview of the Autonomic Nervous System Dr. Yvette Taché – University of California, Los Angeles (20 min)
9:50 - 11:20 a.m. --- Session 1: Neural Circuits in Organs and Diseases – Opportunities for Neuromodulation in the Lower Urinary Tract --- Session Chair: Dr. Helen Raybould
Neural Control and Neuromodulation of Lower Urinary Tract Function Dr. William C. de Groat – University of Pittsburgh (20 min)
Technology Response: Dr. Graham Creasey – Stanford (15 min)	Slides are not available
Dr. Nico Rijkhoff – Aalborg University (15 min)
Open Discussion (40 min)	Not Applicable
12:00 - 12:30 p.m. --- Session 2: Data Coordination Panel – Case Studies and Ontologies --- Session Chair: Dr. Vinay Pai
Dr. Roger Mark – Massachusetts Institute of Technology
Dr. Mark Musen – Stanford University	Slides are not available
Dr. Stephen Schürer – University of Miami
Dr. Matthew McAuliffe – NIH, CIT
12:30 - 2:45 p.m. --- Session 3: Neural Circuits in Organs and Diseases – Opportunities for Neuromodulation in Complex Systems --- Session Chair: Dr. Ranu Jung
Neuromodulation: the Autonomic Nervous System and Gastrointestinal Tract Disorders Dr. Terry Powley – Purdue University (20 min)
Technology Response: Gastrointestinal System Dr. Richard McCallum – Texas Tech University Health Sciences Center (15 min)
Open Discussion (15 min)	Not Applicable
Autonomic Regulation of Cardiac Excitability: Scientific Foundations & Human Arrhythmia Dr. Kalyanam Shivkumar – University of California, Los Angeles (20 min)
Technology Response: Arrhythmia Dr. Igor Efimov – George Washington University (15 min)
Modulation of Cardiac Afferent Signaling: A New Strategy for Heart Failure Therapy? Dr. Irving Zucker – University of Nebraska (20 min)
Technology Response: Heart Failure Dr. Hani Sabah – Henry Ford Health System (15 min)
Open Discussion (15 min)	Not Applicable
3:15 - 5:00 p.m. --- Session 3: Neural Circuits in Organs and Diseases – Opportunities for Neuromodulation in Complex Systems --- Session Chair: Dr. Ranu Jung
Opportunities for Electrical Neuromodulation of Respiratory Function Dr. Marian Kollarik – Johns Hopkins University (20 min)
Technology Response: Airway/Lung Dr. Brendan Canning – Johns Hopkins University (15 min)	Slides are not available
Open Discussion (15 min)	Not Applicable
Vagus Nerve Blockade for the Treatment of Obesity and Its Co-morbid Illnesses Dr. Sayeed Ikramuddin – University of Minnesota (20 min)
Open Discussion (35 min)	Not Applicable
5:00 p.m. --- Adjourn
Day 2: Thursday, February 26, 2015	Slides Approved for Dissemination
8:00 - 10:00 a.m. --- Session 4: Mechanisms of Nerve/Organ Interaction --- Session Chair: Dr. Yvette Taché
The Autonomic Innervation of the Pancreatic Islet: A Cautionary Tale of Mouse and Human Studies Alejandro Caicedo – University of Miami (25 min)	Slides are not available
The Inflammatory Reflex: A Mechanistic Approach to Bioelectronic Medicine Dr. Kevin Tracey – Feinstein Institute for Medical Research (25 min)	Slides are not available
Plasticity on the Vagal Afferent Pathway: Nutrient and Microbial Drivers Dr. Helen Raybould – University of California, Davis (25 min)
Duodeno-pancreatic Innervation: A Dichotomous Neural System with Implications for Inflammation and Metabolic Disease Dr. Pankaj Jay Pasricha – Johns Hopkins School of Medicine (25 min)
Open Discussion (20 min)	Not Applicable
10:30 - 11:30 a.m. --- Session 5: Cross-Cutting Technologies --- Session Chair: Dr. Graham Creasey
Animal Models Dr. Viviana Gradinaru – California Institute of Technology (10 min)
Dr. Kim Butts Pauly – Stanford University (10 min)
Human Models Dr. Ranu Jung – Florida International University (10 min)
Dr. Kevin Kilgore – Case Western Reserve University (10 min)
Open Discussion (20 min)	Not Applicable
11:30 - 11:45 a.m. --- Parallel Efforts - ElectRx and Bioelectronics
Dr. Dr. Doug Weber – DARPA	Slides are not available
Dr. Roy Katso – GlaxoSmithKline
11:45 a.m. - 12:45 p.m. --- Opportunities for the SPARC Program
Dr. Dr. William C. de Groat – University of Pittsburgh Dr. Kevin Kilgore – Case Western Reserve University
12:45 p.m. --- Adjourn