Translational Partnerships for Human Functional Mapping and New Indications
SPARC3 supports translational partnerships between industry and SPARC investigators to produce proofs of concept for new nerve stimulation indications and to study functional neuromodulation in the context of human clinical studies.
SPARC 3 facilitates these partnerships, through template agreements and leveraging NIH Common Fund support. Moreover, data from these studies may be helpful when integrated with information generated by the Anatomical and Functional Mapping component and the Next Generation Tools and Technologies component.
Currently and previously funded research:
Specific objectives for Pre-clinical Development of Existing Market-Approved Devices to Support New Market Indications projects differ based on the respective funding opportunities listed below. These translational projects, also listed below, leverage devices made available through the SPARC Device Portal.
- (RFA-RM-16-009) Three projects funded through 2-year, U18 Research Demonstration Cooperative Agreements
SMART SPINAL CORD STIMULATION FOR GASTROPARESIS: This project aims to treat gastroparesis using spinal cord stimulation (SCS) in a three-series strategy, followed by a chronic study utilizing insights gained using an FDA approved SCS implant in a canine model for gastroparesis. The first set of experiments will tackle gastric motility via SCS in an animal model of gastroparesis; the second set of experiments will deal with gastric accommodation; and the third with visceral hypersensitivity.
- (RFA-RM-16-027) Two projects funded through 2-year, U18 Research Demonstration Cooperative Agreements
No publications at this time.
This page last reviewed on January 23, 2020