Funded Research

Stimulating Peripheral Activity to Relieve Conditions (SPARC): Data Coordination, Mapping, and Modeling Center (OT3) RFA-RM-16-008
PI Name Institution Name Title
HUNTER, PETER JOHN UNIVERSITY OF AUCKLAND Multi-scale, multi-organ, multi-species SPARC map management
KUSTER, NIELS IT'IS FOUNDATION Open Platform for Online Simulations for Stimulating Peripheral Activity to Relieve Conditions – o2S2PARC
WAGENAAR, JOOST B BLACKFYNN, INC. Blackfynn: A scalable and sustainable platform for scientific data integration and analysis

 

Stimulating Peripheral Activity to Relieve Conditions (SPARC):  Foundational Peripheral Neuroanatomy and Functional Neurobiology in Under-Studied Organs (U01) RFA-RM-17-003
PI Name Institution Name Title
FRENETTE, PAUL S ALBERT EINSTEIN COLLEGE OF MEDICINE, INC Evaluating neural circuitry of the bone marrow
KOLLARIK, MARIAN JOHNS HOPKINS UNIVERSITY Ionic and Structural Mechanisms for Sensory Neuromodulation of the Esophagus
OSBORN, JOHN W (contact) 
THOMAS, MARK JOHN 
VULCHANOVA, LYUDMILA H
UNIVERSITY OF MINNESOTA Structural and functional neurobiology of renal nerves: A platform for neuromodulation of renal function
SCHELLER, ERICA LYNN WASHINGTON UNIVERSITY PERIPHERAL NERVE DISTRIBUTION AND FUNCTION WITHIN THE SKELETON

 

Limited Competition - Stimulating Peripheral Activity to Relieve Conditions (SPARC):  Technologies to Understand the Control of Organ Function by the Peripheral Nervous System (OT2) RFA-RM-17-010
PI Name Institution Name Title
GAUNT, ROBERT A UNIVERSITY OF PITTSBURGH AT PITTSBURGH Soft Silicone Electrode Nets: implantable technology for visceral organ neural interfacing and functional evaluation
GREGERSEN, HANS (contact) 
KASSAB, GHASSAN S
CALIFORNIA MEDICAL INNOVATIONS INSTITUTE Fecobionics device for mapping colonic and anorectal neuromuscular function
GRILL, WARREN M  DUKE UNIVERSITY Modeling Activation and Block of Autonomic Nerves for Analysis and Design
JENKINS, MICHAEL W CASE WESTERN RESERVE UNIVERSITY Infrared Neuromodulation Reveals a New Understanding of Ganglion Organization

 

NIH Support for Conferences and Scientific Meetings (Parent R13) PA-16-294
PI Name Institution Name Title
ROLANDI, MARCO UNIVERSITY OF CALIFORNIA SANTA CRUZ Asilomar Bioelectronics Symposium 2017

 

Stimulating Peripheral Activity to Relieve Conditions (SPARC): Pre-clinical Development of Existing Market-approved Devices to Support New Market Indications (U18) RFA-RM-16-027
PI Name Institution Name Title
CHEN, PENG-SHENG INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS Subcutaneous nerve stimulation for arrhythmia control.
HORN, CHARLES CHRISTOPHER UNIVERSITY OF PITTSBURGH AT PITTSBURGH Closed-loop neuroelectric control of emesis and gastric motility

 

Limited Competition - Stimulating Peripheral Activity to Relieve Conditions (SPARC): Comprehensive Functional Mapping of Neuroanatomy and Neurobiology of Organs (OT2) RFA-RM-15-018
PI Name Institution Name Title
BOLSER, DONALD C UNIVERSITY OF FLORIDA Functional mapping of peripheral and central circuits for airway protection and breathing
HOWARD, MARTHE J UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS Anatomical-Functional Mapping of Enteric Neural Circuits
HUBSCHER, CHARLES H. (contact) 
HARKEMA, SUSAN J 
UNIVERSITY OF LOUISVILLE Functional Mapping with Lumbosacral Epidural Stimulation for Restoration of Bladder Function After Spinal Cord Injury
POWLEY, TERRY L. PURDUE UNIVERSITY Mapping Stomach Autonomic Circuitry and Function for Neuromodulation of Gastric Disorders
SHIVKUMAR, KALYANAM (contact) 
FOWLKES, CHARLESS 
GRADINARU, VIVIANA 
HABECKER, BETH A 
LIBERLES, STEPHEN DANIEL 
PATERSON, DAVID 
ZUCKER, IRVING H
UNIVERSITY OF CALIFORNIA LOS ANGELES Comprehensive Structural and Functional Mapping of the Mammalian Cardiac Nervous System
TACHE, YVETTE FRANCE UNIVERSITY OF CALIFORNIA LOS ANGELES Comprehensive Structural and Functional Mapping of Mammalian Colonic Nervous System

 

Limited Competition - Stimulating Peripheral Activity to Relieve Conditions (SPARC): Foundational Functional Mapping of Neuroanatomy and Neurobiology of Organs (OT2) RFA-RM-15-020
PI Name Institution Name Title
CAMPBELL-THOMPSON, MARTHA L UNIVERSITY OF FLORIDA Neuromodulation-based treatment of diabetes: identifying anatomical and physiological pancreatic innervation targets
KEAST, JANET R UNIVERSITY OF MELBOURNE Understanding functional connectivity of sensory and motor pathways to specific regions of the lower urinary tract.
LEWIS, STEPHEN JOHN  CASE WESTERN RESERVE UNIVERSITY Functional Mapping of the afferent and Efferent Projections of the Superior Cervical Ganglion Interactome
MUENZBERG-GRUENING, HEIKE LSU PENNINGTON BIOMEDICAL RESEARCH CTR Genetically-based neuro-modulation of adipose tissue functions
NAPADOW, VITALY  MASSACHUSETTS GENERAL HOSPITAL Mapping the linkage between auricular vagus nerve receptors and cardiovagal modulation
REARDON, COLIN (contact) 
RAYBOULD, HELEN E
UNIVERSITY OF CALIFORNIA AT DAVIS Mapping of the neuro-immune interface
SHEN, XILING DUKE UNIVERSITY Functional mapping of efferent gut neuroepithelial circuits
SOUTHARD-SMITH, E MICHELLE VANDERBILT UNIVERSITY MEDICAL CENTER ENSMAP: Molecular and Functional Mapping of the Enteric Nervous System
SUN, XIN (contact) 
WANG, FAN
UNIVERSITY OF WISCONSIN-MADISON Foundational Mapping of the Neural Circuits that Control Intrinsic Lung Function
ZELTSER, LORI M  COLUMBIA UNIVERSITY HEALTH SCIENCES Foundational tools to study the impacts of sympathetic activity on the neuroanatomy and function of brown adipose tissue

 

Limited Competition - Stimulating Peripheral Activity to Relieve Conditions (SPARC):  Technologies to Understand the Control of Organ Function by the Peripheral Nervous System (OT2) RFA-RM-16-003
PI Name Institution Name Title
CLARK, HEATHER A NORTHEASTERN UNIVERSITY Optical Nanosensors Detect Neurotransmitter Release in the Peripheral Nervous System
DAMASER, MARGOT S. (contact) 
BOURBEAU, DENNIS
CLEVELAND CLINIC LERNER COM-CWRU Conscious ambulatory bladder monitoring to understand neural control of lower urinary tract function
MCLAUGHLIN, BRYAN L MICRO-LEADS, INC. Epidural Current-Steering for Selective Modulation of Lower Urinary Tract Function
SEYMOUR, JOHN P (contact) 
BRUNS, TIMOTHY M. 
YOON, EUISIK 
UNIVERSITY OF MICHIGAN Highly-compliant Microneedle Arrays for Peripheral Nerve Mapping
STANLEY, SARAH AMY ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Remote Modulation of the Peripheral Nervous System
WEIR, RICHARD FERGUS FFRENCH UNIVERSITY OF COLORADO DENVER Development of a Bidirectional Optogenetic Minimally Invasive Peripheral Nerve Interface with Single Axon Read-in & Read-out Specificity

 

Pre-clinical Development of Existing Market-approved Devices to Support New Market Indications (U18) RFA-RM-16-009
PI Name Institution Name Title
CANNING, BRENDAN J (contact) 
KOLLARIK, MARIAN 
MITZNER, WAYNE 
JOHNS HOPKINS UNIVERSITY Neuromodulation for Asthma
CHEN, JIANDE JOHNS HOPKINS UNIVERSITY Smart spinal cord stimulation for gastroparesis
YIN, JIEYUN NONE TRANSTIMULATION RESEARCH, INC. Vagal Nerve Stimulation for Diabetes

 

Exploratory Technologies to Understand the Control of Organ Function by the Peripheral Nervous System for SPARC (U18) RFA-RM-15-002
PI Name Institution Name Title
ARDELL, JEFFREY L (contact) 
KIPKE, DARYL R 
SHIVKUMAR, KALYANAM 
UNIVERSITY OF CALIFORNIA LOS ANGELES Distributed electrode system for high-fidelity cardio-neural mapping
BRUNS, TIMOTHY M. (contact) 
YOON, EUISIK
UNIVERSITY OF MICHIGAN Development of a novel multi-modal spinal root interface
DAVIS, BRIAN M (contact) 
GLORIOSO, JOSEPH C.
UNIVERSITY OF PITTSBURGH AT PITTSBURGH Novel viral tools for control of bladder function and pain
DURAND, DOMINIQUE M (contact) 
LEWIS, STEPHEN JOHN
CASE WESTERN RESERVE UNIVERSITY Novel nanowire interface with the autonomic nervous system to study hypertension
FARAJIDAVAR, AYDIN (contact) 
KIANI, MEHDI  
MILLER, LARRY S
NEW YORK INST OF TECHNOLOGY An Implantable Wireless System To Study Gastric Neurophysiology
GEREAU, ROBERT (contact) 
ROGERS, JOHN
WASHINGTON UNIVERSITY Soft, conformal wireless optoelectronic systems for the long-term neuromodulation of bladder function
HORN, CHARLES CHRISTOPHER (contact) 
JENKINS, MICHAEL W.
UNIVERSITY OF PITTSBURGH AT PITTSBURGH Defining gastric vagal mechanisms underlying emetic activation using novel electrophysiological and optical mapping technology
HOWARD, MARTHE J UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS Tool Building to Inform Structure-Functions relationships in the Autonomic Nervous System
OKUSA, MARK DOUGLAS (contact) 
HOSSACK, JOHN A
UNIVERSITY OF VIRGINIA Tailoring ultrasound technology to explore mechanisms of activation of the splenic neuroimmune axis in attenuating acute organ injury
STROHL, KINGMAN PERKINS CASE WESTERN RESERVE UNIVERSITY A Tool for Neurotheraputic Therapy for Sleep Disordered Breathing
VULCHANOVA, LYUDMILA H UNIVERSITY OF MINNESOTA Selective peripheral neuromodulation through organ-specific AAV-mediated gene transfer
WELLS, JAMES M (contact) 
HELMRATH, MICHAEL A
CINCINNATI CHILDRENS HOSP MED CTR Establishment of in vitro and in vivo models of human gastrointestinal organoids with a functional ENS

 

This page last reviewed on November 1, 2017