Videos

This video features remarks from each of the Track 2 Replication Exemplar winners of the NIH Replication Prize. Track 2 winners are pioneering researchers who have creatively and successfully integrated replication into their standard research practice. Their strategies have shown measured success in improving research rigor and building trust in scientific outcomes.

For more information about the NIH Replication Prize, visit: https://go.nih.gov/ufwhETJ

For more information about the NIH Common Fund Replication Initiative, visit: https://go.nih.gov/HxQObLk

The NIH Common Fund’s Discovery Dialogues Webinar Series is designed to highlight groundbreaking NIH Common Fund scientific advances and program outcomes. On May 6, 2026, speakers from the NIH Common Fund Transformative Health Disparities (THD) Program discussed innovative research projects to understand and reduce health disparities. The presenters were Poorna Kushalnagar, Ph.D., Director of the Center of Deaf Health Excellence, Strategic Research Officer, and Professor of Psychology at Gallaudet University; and Gabriela Buccini, Ph.D., MSc, IBCLC, an Assistant Professor at the University of Nevada Las Vegas School of Public Health. They presented highlights, progress, and lessons learned from research projects aimed at improving health within their communities.

Learn more about the Technology Development Centers, a pillar of the NIH Common Fund’s Complement-ARIE Program to develop innovative New Approach Methodologies (NAMs)!

The Complement-ARIE program will speed the development, standardization, validation, and use of human-based NAMs, which are lab or computer-based research approaches intended to more accurately model human biology, and complement, or in some cases, replace traditional research models.

Additional information is available on the Common Fund website: https://commonfund.nih.gov/complementarie

Experts from the Office of Women’s Health (ORWH) and the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) have joined to launch a new initiative leveraging advancements in computational modeling to deepen understanding of sex-specific hormonal biology.

The goal of this initiative is to promote the development of computer-based methods that model and simulate hormone homeostasis, or activity during steady-state biological processes.

To view the ROA, visit: https://dpcpsi.nih.gov/hormone-homeostasis/ROA

To view frequently asked questions, visit: https://dpcpsi.nih.gov/hormone-homeostasis/FAQ

To view an audio described version of this video, visit: https://youtu.be/mKNnjwlxjGA

Experts from the Office of Women’s Health (ORWH) and the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) have joined to launch a new initiative leveraging advancements in computational modeling to deepen understanding of sex-specific hormonal biology.

The goal of this initiative is to promote the development of computer-based methods that model and simulate hormone homeostasis, or activity during steady-state biological processes.

To view the ROA, visit: https://dpcpsi.nih.gov/hormone-homeostasis/ROA

To view frequently asked questions, visit: https://dpcpsi.nih.gov/hormone-homeostasis/FAQ

To view an audio described version of this video, visit: https://youtu.be/yWpP6BUfK70

The NIH Common Fund’s Patient-Reported Outcomes Measurement Information System (PROMIS) program created new paradigms for how clinical research information is collected, used, and reported.

The PROMIS program addressed a need in the clinical research community for a rigorously tested patient reported outcome measurement tool that leveraged advances in information technology, psychometrics, and health survey research.

PROMIS has had a substantial impact, with approximately 70 domains measuring pain, fatigue, depression, anxiety, sleep disturbance, physical function, social function, and sexual function, among other areas, available for use today.

To learn more about ongoing PROMIS activities, visit: https://www.healthmeasures.net/explore-measurement-systems/promis

For more information about NIH support of PROMIS, visit: https://commonfund.nih.gov/promis

The NIH Common Fund’s Stimulating Peripheral Activities to Relieve Conditions (SPARC) Program announced winners of the Neuromod Prize.

The Neuromod Prize is a $9.8 million competition to accelerate the development of targeted neuromodulation therapies, that is therapies delivered through electrical stimulation of nerves. With this competition, the SPARC program is using open innovation to foster approaches that are capable of selectively targeting multiple organs and functions without unintended side effects.

To learn more about the Neuromod Prize, visit: neuromodprize.com
To learn more about the SPARC program, visit: sparc.science

The Common Fund’s Stimulating Peripheral Activity to Relieve Conditions (SPARC) program accelerates development of therapeutic devices that modulate electrical activity in nerves to improve organ function. The SPARC Reconstructing Vagal Anatomy (REVA) initiative is creating more precise and detailed maps of the human vagus nerve, a bioelectronic highway that carries two-way electrical signals between the brain and internal organs of the body. This video describes the REVA initiative and how it is working towards advancing science and improving patients' lives.

To learn more about SPARC visit: https://commonfund.nih.gov/sparc
To view data generated through REVA, visit the SPARC portal: https://sparc.science

NIH program staff discuss funding opportunity RFA-RM-25-003 and provide information about the application and review process.

View the funding opportunity here: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-25-003.html

Learn more about the NIH Common Fund HRHR Pioneer Award at our website: https://commonfund.nih.gov/tra

An audio-described version of this webinar will be available soon.

NIH program staff discuss funding opportunity RFA-RM-25-001 and provide information about the application and review process.

View the funding opportunity here: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-25-001.html

Learn more about the NIH Common Fund HRHR Pioneer Award at our website: https://commonfund.nih.gov/pioneer

An audio described version will be available soon.

NIH program staff discuss funding opportunity RFA-RM-25-002 and provide information about the application and review process.

View the funding announcement here: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-25-002.html

Learn more about the NIH Common Fund New Innovator Award at our website: https://commonfund.nih.gov/newinnovator

An audio described version will be available soon.

Part of the High-Risk, High-Reward Research program, the New Innovator Award supports early career investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the NIH mission.

Part of the High-Risk, High-Reward Research program, the Pioneer Award supports scientists with outstanding records of creativity pursuing new research directions to develop pioneering approaches to major challenges in biomedical, social science, and behavioral research.

Part of the High-Risk, High-Reward Research program, the Transformative Research Award supports individuals or teams proposing transformative projects that are inherently risky and untested but have the potential to create or overturn fundamental paradigms and may require very large budgets.

In this video, researchers supported by the NIH Common Fund’s 4D Nucleome program discuss the impacts of their research and how it led to important discoveries about DNA organization inside cells across space and time.

For more information about the #NIH Common Fund 4D Nucleome program, visit: https://commonfund.nih.gov/4DNucleome

For more information about the NIH Common Fund, visit: https://commonfund.nih.gov

A non-audio described version of this video is available here: https://youtu.be/2EQZg6Z-4S4

In this video, researchers supported by the NIH Common Fund’s 4D Nucleome program discuss the impacts of their research and how it led to important discoveries about DNA organization inside cells across space and time.

For more information about the #NIH Common Fund 4D Nucleome program, visit: https://commonfund.nih.gov/4DNucleome

For more information about the NIH Common Fund, visit: https://commonfund.nih.gov

An audio described version of this video is available here: https://youtu.be/lPQrar5g-rU