Funded Research

FOA for fiscal year 2017 cohorts: Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01).
The following principal investigators were awarded access to sequence structural birth defects cohorts or childhood cancer cohorts at the Broad Institute's or St. Jude Children’s Research Hospital/Hudson-Alpha Institute for Biotechnology's NIH supported sequencing center.
PI Name Institution Name Title
BOYADJIEV BOYD,  SIMEON A (contact)
ROMITTI, PAUL A
UNIVERSITY OF CALIFORNIA DAVIS Whole genome sequencing of nonsyndromic craniosynostosis
BUTALI, AZEEZ (contact)
BEATY, TERRI H.
UNIVERSITY OF IOWA Whole Genome Sequencing of African and Asian Orofacial Clefts Case-Parent Triads
CHUNG, WENDY K (contact)
SHEN, YUFENG  
COLUMBIA UNIVERSITY HEALTH SCIENCES Genomic Analysis of Congenital Diaphragmatic Hernia and Associated Congenital Anomalies
HAKONARSON, HAKON (contact)
RESNICK, ADAM CAIN
SLEIMAN, PATRICK MARTIN
CHILDREN'S HOSPITAL OF PHILADELPHIA Genetics at the Intersection of Childhood Cancer and Birth Defects
LUQUETTI, DANIELA VARELA UNIVERSITY OF WASHINGTON Craniofacial Microsomia: Genetic Causes and Pathway Discovery
SCHIFFMAN, JOSHUA DAVID UNIVERSITY OF UTAH Expanded Ewing sarcoma cohort for tumor genomics and association with DNA repair deficiencies, clinical presentation, and outcome
SIEGEL, DAWN H MEDICAL COLLEGE OF WISCONSIN Genomic analysis of a cohort with infantile hemangiomas associated with multi-organ structural birth defects
SOBREIRA, NARA JOHNS HOPKINS UNIVERSITY Genome-wide Sequencing to Identify the Genes Responsible for Enchondromatoses and Related Malignant Tumors

Development of the Gabriella Miller Kids First Pediatric Data Resource Center (U2C) RFA-RM-16-010

PI Name Institution Name Title
RESNICK, ADAM CAIN (contact) 
DAVIS-DUSENBERY, BRANDI NICOLE 
FERRETTI, VINCENT 
GROSSMAN, ROBERT L. 
HAKONARSON, HAKON 
KURAL, DENIZ 
MARGOLIN, ADAM ARNE 
STEIN, LINCOLN D 
TAYLOR, DEANNE MARIE 
VOLCHENBOUM, SAMUEL
CHILDREN'S HOSP OF PHILADELPHIA Innovation through collaboration at the intersection of childhood development and cancer: a platform for the Gabriella Miller Kids First Pediatric Data Resource Center

 

FOA for fiscal year 2016 cohorts: Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01).
The following principal investigators were awarded access to sequence structural birth defects cohorts or childhood cancer cohorts at the Broad Institute's or St. Jude Children’s Research Hospital/Hudson-Alpha Institute for Biotechnology's NIH supported sequencing center.
PI Name Institution Name Title
CHUNG, WENDY K (contact) 
SHEN, YUFENG
COLUMBIA UNIVERSITY HEALTH SCIENCES Genomic Analysis of Congenital Diaphragmatic Hernia and Associated Congenital Anomalies
MARAZITA, MARY L. (contact) 
FEINGOLD, ELEANOR
UNIVERSITY OF PITTSBURGH AT PITTSBURGH Kids First: Genomics of Orofacial Cleft Birth Defects in Latin American Families
MARIS, JOHN M CHILDREN'S HOSP OF PHILADELPHIA Genetic basis of neuroblastoma initiation and progression
MULLIGHAN, CHARLES G (contact) 
METZGER, MONIKA  
NICHOLS, KIM ERIKA 
SANDLUND, JOHN  
YANG, JUN J
ST. JUDE CHILDREN'S RESEARCH HOSPITAL Genomic analysis of familial leukemia
PLON, SHARON E. BAYLOR COLLEGE OF MEDICINE Identifying novel cancer susceptibility mutations from unselected childhood cancer patient and parent trios
RIOS, JONATHAN UT SOUTHWESTERN MEDICAL CENTER Genomics of Orthopaedic Disease Program
SEIDMAN, CHRISTINE E. HARVARD MEDICAL SCHOOL Discovery of De Novo and Inherited Mutations that Cause Prevalent Birth Defects
SHEN, JUN (contact) 
MORTON, CYNTHIA CASSON
BRIGHAM AND WOMEN'S HOSPITAL Hear-n-Seq: Sequencing Kids First for Hearing

 

Genome Sequencing Center for the Gabriella Miller Kids First Pediatric Research Program (U24) RFA-RM-16-001
PI Name Institution Name Title
GABRIEL, STACEY BROAD INSTITUTE, INC. Genome Sequencing in support of the Gabriella Miller Kids First Pediatric Research Program
LEVY, SHAWN E (contact) 
ZHANG, JINGHUI
HUDSON-ALPHA INSTITUTE FOR BIOTECHNOLOGY Characterizing pediatric genomes through an optimized sequencing approach

 

FOA for fiscal year 2015 cohorts: Discovery of the Genetic Basis of Structural Birth Defects and of Childhood Cancers: Gabriella Miller Kids First Pediatric Research Program (X01).
The following principal investigators were awarded access to sequence structural birth defects cohorts or childhood cancer cohorts at Baylor College of Medicine's or Washington University's NIH supported sequencing center.
PI Name Institution Name Title
CHUNG, WENDY K. COLUMBIA UNIVERSITY HEALTH SCIENCES Genomic Analysis of Congenital Diaphragmatic Hernia
ENGLE, ELIZABETH C. CHILDREN'S HOSPITAL CORPORATION BCH Structural Birth Defects Collaboration: Syndromic cranial dysinnervation disorders
MARAZITA, MARY L. UNIVERSITY OF PITTSBURGH Genomic Studies of Orofacial Cleft Birth Defects
ONEL, KENAN THE UNIVERSITY OF CHICAGO An Integrated Clinical and Genomic Analysis of Treatment Failure in Pediatric Osteosarcoma
SCHIFFMAN, JOSHUA, DAVID UNIVERSITY OF UTAH Genetic Contribution to Ewing Sarcoma in 330 parent-Offspring Trios
SEIDMAN, CHRISTINE E, PRESIDENT AND FELLOWS OF HARVARD COLLEGE Discovery of the Genetic Basis of Structural Heart and Other Birth Defects
VILAIN, ERIC UNIVERSITY OF CALIFORNIA LOS ANGELES Genetic Basis of Disorders/Differences of Sex Development (DSD)

 

The following administrative supplements were awarded to existing NIH grants to provide DNA sequencing services for successful applicants of PAR-15-259 “Discovery of the Genetic Basis of Structural Birth Defects and of Childhood Cancers: Gabriella Miller Kids First Pediatric Research Program (X01).
PI Name Institution Name Title
GIBBS, RICHARD A BAYLOR COLLEGE OF MEDICINE The Human Genome Sequencing Center
WILSON, RICHARD K WASHINGTON UNIVERSITY A Platform for Large-Scale Genomic Discovery

This page last reviewed on August 2, 2017