Science Highlights | NIH Common Fund

Science Highlights

A processed reconstruction of a synapse from an electron tomogram.

CryoET Technology Explores Connections in the Brain

A spherical 3D molecular structure from cryogenic electron microscopy. The structure is mostly grey with teal and orange highlights.

CryoEM structures unravel a molecular mystery of hepatitis B infection

IDeA-eligible states of the U.S. map.

A great "IDeA" for broadening access to cryoEM

In neurodegenerative diseases including Alzheimer’s and Amyotrophic Lateral Sclerosis (ALS), proteins form abnormal clumps in the brain that can contribute to neuron loss. Among these proteins, Tau is an important protein for normal physiologic function, but is also well known to form rope-like aggregates, or clumps, known as tau fibrils in neurodegenerative diseases. Evidence suggests that...

CryoEM structure reveals features of protein aggregate formation in the brain

Detailed image (left) created by the research group led by Dr. Aashish Manglik (right) using cryoEM data.

CryoEM Enables a Clearer Picture of Neuropeptide Signaling and Neuropsychiatric Disorders

Training.

Building a Bigger Toolbox to Study Antibiotic Resistance

Image credit: National Center for CryoEM Access & Training (NCCAT)

Putting the Freeze on COVID-19: Collecting Images of SARS-CoV-2 Using Cryoelectron Microscopy

The Medical Research Funding concept.

NIH Funds National Network for Cryoelectron Tomography

This page last reviewed on February 21, 2025

Scroll To Top