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Program Highlights
IDeA-eligible states of the U.S. map.

A great "IDeA" for broadening access to cryoEM

Imagine seeing the natural shape of biological molecules so closely that you can start to identify individual atoms. This dream is a reality for many…

In neurodegenerative diseases including Alzheimer’s and Amyotrophic Lateral Sclerosis (ALS), proteins form abnormal clumps in the brain that can contribute to neuron loss. Among these proteins, Tau is an important protein for normal physiologic function, but is also well known to form rope-like aggregates, or clumps, known as tau fibrils in neurodegenerative diseases. Evidence suggests that...

CryoEM structure reveals features of protein aggregate formation in the brain

In neurodegenerative diseases including Alzheimer’s and Amyotrophic Lateral Sclerosis (ALS), proteins form abnormal clumps in the brain that can…

Detailed image (left) created by the research group led by Dr. Aashish Manglik (right) using cryoEM data.

CryoEM Enables a Clearer Picture of Neuropeptide Signaling and Neuropsychiatric Disorders

CryoEM may one day lead to the design of better therapies for neurological and psychiatric diseases.

Training.

Building a Bigger Toolbox to Study Antibiotic Resistance

Understanding the form and function of biological molecules expands our knowledge of how living things work.

Image credit: National Center for CryoEM Access & Training (NCCAT)

Putting the Freeze on COVID-19: Collecting Images of SARS-CoV-2 Using Cryoelectron Microscopy

In late 2019, the virus SARS-CoV-2 was identified as the cause of the novel respiratory disease COVID-19.

The Medical Research Funding concept.

NIH Funds National Network for Cryoelectron Tomography

The NIH Common Fund's Transformative High-Resolution Cryoelectron Microscopy (CryoEM) Program has funded the National Network for Cryoelectron…

This page last reviewed on September 13, 2023