| Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction. |
Kulczyk, Arkadiusz W; Sorzano, Carlos Oscar S; Grela, Przemysław; Tchórzewski, Marek; Tumer, Nilgun E; Li, Xiao-Ping |
The Journal of biological chemistry |
36528064 |
2023 Jan |
| Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM. |
Monsen, Robert C; Chua, Eugene Y D; Hopkins, Jesse B; Chaires, Jonathan B; Trent, John O |
Nucleic acids research |
36715343 |
2023 Feb 28 |
| Control of transcription elongation and DNA repair by alarmone ppGpp. |
Weaver, Jacob W; Proshkin, Sergey; Duan, Wenqian; Epshtein, Vitaly; Gowder, Manjunath; Bharati, Binod K; Afanaseva, Elena; Mironov, Alexander; Serganov, Alexander; Nudler, Evgeny |
Nature structural & molecular biology |
36997761 |
2023 May |
| Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. |
Doran, Matthew H; Rynkiewicz, Michael J; Pavadai, Elumalai; Bodt, Skylar M L; Rasicci, David; Moore, Jeffrey R; Yengo, Christopher M; Bullitt, Esther; Lehman, William |
The Journal of general physiology |
36459134 |
2023 Feb 06 |
| Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. |
Doran, Matthew H; Rynkiewicz, Michael J; Rasicci, David; Bodt, Skylar M L; Barry, Meaghan E; Bullitt, Esther; Yengo, Christopher M; Moore, Jeffrey R; Lehman, William |
The Journal of general physiology |
36633586 |
2023 Mar 06 |
| Mechanism of Ca2+ transport by ferroportin. |
Shen, Jiemin; Wilbon, Azaan Saalim; Zhou, Ming; Pan, Yaping |
eLife |
36648329 |
2023 Jan 17 |
| Structure and mechanism of the alkane-oxidizing enzyme AlkB. |
Guo, Xue; Zhang, Jianxiu; Han, Lei; Lee, Juliet; Williams, Shoshana C; Forsberg, Allison; Xu, Yan; Austin, Rachel Narehood; Feng, Liang |
Nature communications |
37069165 |
2023 Apr 17 |
| Cryo-EM reveals the molecular basis oflaminin polymerization and LN-lamininopathies. |
Kulczyk, Arkadiusz W; McKee, Karen K; Zhang, Ximo; Bizukojc, Iwona; Yu, Ying Q; Yurchenco, Peter D |
Nature communications |
36658135 |
2023 Jan 19 |
| Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex. |
Patel, Avinash B; Qing, Jinkang; Tam, Kelly H; Zaman, Sara; Luiso, Maria; Radhakrishnan, Ishwar; He, Yuan |
Nature communications |
37244892 |
2023 May 27 |
| ManiLoco: A VR-Based Locomotion Method for Concurrent Object Manipulation. |
Wan, Dayu; Guo, Xiaolei; Dong, Jiahui; Mousas, Christos; Chen, Yingjie |
Proceedings of the ACM on computer graphics and interactive techniques |
37293199 |
2023 May |
| Structural basis for substrate selection by the SARS-CoV-2 replicase. |
Malone, Brandon F; Perry, Jason K; Olinares, Paul Dominic B; Lee, Hery W; Chen, James; Appleby, Todd C; Feng, Joy Y; Bilello, John P; Ng, Honkit; Sotiris, Johanna; Ebrahim, Mark; Chua, Eugene Y D; Mendez, Joshua H; Eng, Ed T; Landick, Robert; Götte, Matth |
Nature |
36725929 |
2023 Feb |
| Conformational switching and flexibility in cobalamin-dependent methionine synthase studied by small-angle X-ray scattering and cryo-electron microscopy. |
Watkins, Maxwell B; Wang, Haoyue; Burnim, Audrey; Ando, Nozomi |
bioRxiv : the preprint server for biology |
36798380 |
2023 Feb 12 |
| A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. |
Podgorski, Jennifer M; Freeman, Krista; Gosselin, Sophia; Huet, Alexis; Conway, James F; Bird, Mary; Grecco, John; Patel, Shreya; Jacobs-Sera, Deborah; Hatfull, Graham; Gogarten, Johann Peter; Ravantti, Janne; White, Simon J |
Structure (London, England : 1993) |
36649709 |
2023 Mar 02 |
| Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1. |
Srivastava, Dhiraj; Yadav, Ravi P; Singh, Sneha; Boyd, Kimberly; Artemyev, Nikolai O |
Structure (London, England : 1993) |
36657440 |
2023 Mar 02 |
| Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain. |
Harris, Noah J; Jenkins, Meredith L; Nam, Sung-Eun; Rathinaswamy, Manoj K; Parson, Matthew Ah; Ranga-Prasad, Harish; Dalwadi, Udit; Moeller, Brandon E; Sheekey, Eleanor; Hansen, Scott D; Yip, Calvin K; Burke, John E |
bioRxiv : the preprint server for biology |
37090531 |
2023 May 23 |
| Structural interplay of anesthetics and paralytics on muscle nicotinic receptors. |
Goswami, Umang; Rahman, Md Mahfuzur; Teng, Jinfeng; Hibbs, Ryan E |
Nature communications |
37264005 |
2023 Jun 01 |
| Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation. |
Talyzina, Anna; Han, Yan; Banerjee, Chiranjib; Fishbain, Susan; Reyes, Alexis; Vafabakhsh, Reza; He, Yuan |
Molecular cell |
37402369 |
2023 Jun 28 |
| Nanovaccines Displaying the Influenza Virus Hemagglutinin in an Inverted Orientation Elicit an Enhanced Stalk-Directed Antibody Response. |
Frey, Steven J; Carreño, Juan Manuel; Bielak, Dominika; Arsiwala, Ammar; Altomare, Clara G; Varner, Chad; Rosen-Cheriyan, Tania; Bajic, Goran; Krammer, Florian; Kane, Ravi S |
Advanced healthcare materials |
36689343 |
2023 May |
| Structural basis of Rho-dependent transcription termination. |
Molodtsov, Vadim; Wang, Chengyuan; Firlar, Emre; Kaelber, Jason T; Ebright, Richard H |
Nature |
36697824 |
2023 Feb |
| Polγ coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. |
Park, Joon; Herrmann, Geoffrey K; Mitchell, Patrick G; Sherman, Michael B; Yin, Y Whitney |
Nature structural & molecular biology |
37202477 |
2023 Jun |
| Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. |
Zhan, Hong; Unchwaniwala, Nuruddin; Rebolledo-Viveros, Andrea; Pennington, Janice; Horswill, Mark; Broadberry, Roma; Myers, Jonathan; den Boon, Johan A; Grant, Timothy; Ahlquist, Paul |
Proceedings of the National Academy of Sciences of the United States of America |
36693094 |
2023 Jan 31 |
| Cross-protective antibodies against common endemic respiratory viruses. |
Cabán, Madelyn; Rodarte, Justas V; Bibby, Madeleine; Gray, Matthew D; Taylor, Justin J; Pancera, Marie; Boonyaratanakornkit, Jim |
Nature communications |
36781872 |
2023 Feb 13 |
| The role of CenKR in the coordination of Rhodobacter sphaeroides cell elongation and division. |
Lakey, Bryan D; Alberge, François; Parrell, Daniel; Wright, Elizabeth R; Noguera, Daniel R; Donohue, Timothy J |
mBio |
37283520 |
2023 Jun 07 |
| The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems. |
Paraan, Mohammadreza; Nasef, Mohamed; Chou-Zheng, Lucy; Khweis, Sarah A; Schoeffler, Allyn J; Hatoum-Aslan, Asma; Stagg, Scott M; Dunkle, Jack A |
PloS one |
37352230 |
2023 |
| Lysate-to-grid: Rapid Isolation of Native Complexes from Budding Yeast for Cryo-EM Imaging. |
Cooney, Ian; Mack, Deirdre C; Ferrell, Aaron J; Stewart, Michael G; Wang, Shuxin; Donelick, Helen M; Tamayo-Jaramillo, Daniela; Greer, Dakota L; Zhu, Danyang; Li, Wenyan; Shen, Peter S |
Bio-protocol |
36789166 |
2023 Jan 20 |
| Structures of the holo CRISPR RNA-guided transposon integration complex. |
Park, Jung-Un; Tsai, Amy Wei-Lun; Rizo, Alexandrea N; Truong, Vinh H; Wellner, Tristan X; Schargel, Richard D; Kellogg, Elizabeth H |
Nature |
36442503 |
2023 Jan |
| Structural basis of ferroportin inhibition by minihepcidin PR73. |
Wilbon, Azaan Saalim; Shen, Jiemin; Ruchala, Piotr; Zhou, Ming; Pan, Yaping |
PLoS biology |
36649314 |
2023 Jan |
| Conformational switching and flexibility in cobalamin-dependent methionine synthase studied by small-angle X-ray scattering and cryoelectron microscopy. |
Watkins, Maxwell B; Wang, Haoyue; Burnim, Audrey; Ando, Nozomi |
Proceedings of the National Academy of Sciences of the United States of America |
37339208 |
2023 Jun 27 |
| GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. |
Hoppe, Nicholas; Harrison, Simone; Hwang, Sun-Hee; Chen, Ziwei; Karelina, Masha; Deshpande, Ishan; Suomivuori, Carl-Mikael; Palicharla, Vivek R; Berry, Samuel P; Tschaikner, Philipp; Regele, Dominik; Covey, Douglas F; Stefan, Eduard; Marks, Debora S; Reit |
bioRxiv : the preprint server for biology |
37292845 |
2023 May 24 |
| Inhibition of the proton-activated chloride channel PAC by PIP2. |
Mihaljević, Ljubica; Ruan, Zheng; Osei-Owusu, James; Lü, Wei; Qiu, Zhaozhu |
eLife |
36633397 |
2023 Jan 12 |
| Cryo-EM structure of adeno-associated virus 4 at 2.2 Å resolution. |
Zane, Grant; Silveria, Mark; Meyer, Nancy; White, Tommi; Duan, Rui; Zou, Xiaoqin; Chapman, Michael |
Acta crystallographica. Section D, Structural biology |
36762860 |
2023 Feb 01 |
| rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. |
Sekulski, Kamil; Cruz, Victor Emmanuel; Weirich, Christine S; Erzberger, Jan P |
Nature communications |
36864048 |
2023 Mar 02 |
| Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions. |
Donovan, Benjamin T; Chen, Hengye; Eek, Priit; Meng, Zhiyuan; Jipa, Caroline; Tan, Song; Bai, Lu; Poirier, Michael G |
Molecular cell |
36996811 |
2023 Apr 20 |
| 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. |
Srinivas, Pooja; Nosrati, Meisam; Zelinskaya, Natalia; Dey, Debayan; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L |
Proceedings of the National Academy of Sciences of the United States of America |
37307464 |
2023 Jun 20 |
| Structure of human TRPV4 in complex with GTPase RhoA. |
Nadezhdin, Kirill D; Talyzina, Irina A; Parthasarathy, Aravind; Neuberger, Arthur; Zhang, David X; Sobolevsky, Alexander I |
Nature communications |
37353478 |
2023 Jun 23 |
| Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. |
Henderson, Rory; Zhou, Ye; Stalls, Victoria; Wiehe, Kevin; Saunders, Kevin O; Wagh, Kshitij; Anasti, Kara; Barr, Maggie; Parks, Robert; Alam, S Munir; Korber, Bette; Haynes, Barton F; Bartesaghi, Alberto; Acharya, Priyamvada |
Nature communications |
37188681 |
2023 May 15 |
| Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. |
Fan, Minrui; Zhang, Jianxiu; Lee, Chien-Ling; Zhang, Jinru; Feng, Liang |
Nature |
36792826 |
2023 Feb |
| A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. |
Weidenbacher, Payton A-B; Sanyal, Mrinmoy; Friedland, Natalia; Tang, Shaogeng; Arunachalam, Prabhu S; Hu, Mengyun; Kumru, Ozan S; Morris, Mary Kate; Fontenot, Jane; Shirreff, Lisa; Do, Jonathan; Cheng, Ya-Chen; Vasudevan, Gayathri; Feinberg, Mark B; Villi |
Nature communications |
37069151 |
2023 Apr 17 |
| Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. |
Alexander, J Andrew N; Worrall, Liam J; Hu, Jinhong; Vuckovic, Marija; Satishkumar, Nidhi; Poon, Raymond; Sobhanifar, Solmaz; Rosell, Federico I; Jenkins, Joshua; Chiang, Daniel; Mosimann, Wesley A; Chambers, Henry F; Paetzel, Mark; Chatterjee, Som S; Str |
Nature |
36599987 |
2023 Jan |
| Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5. |
Paidimuddala, Bhaskar; Cao, Jianhao; Nash, Grady; Xie, Qing; Wu, Hao; Zhang, Liman |
Nature structural & molecular biology |
36604500 |
2023 Feb |
| Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of Methylococcus capsulatus Soluble Methane Monooxygenase Hydroxylase. |
Ahn, Eungjin; Kim, Byungchul; Park, Soyoung; Erwin, Amanda L; Sung, Suk Hyun; Hovden, Robert; Mosalaganti, Shyamal; Cho, Uhn-Soo |
ACS nano |
36926824 |
2023 Mar 28 |
| 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. |
Srinivas, Pooja; Nosrati, Meisam; Zelinskaya, Natalia; Dey, Debayan; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L |
bioRxiv : the preprint server for biology |
36993224 |
2023 Apr 30 |
| Human TRPV1 structure and inhibition by the analgesic SB-366791. |
Neuberger, Arthur; Oda, Mai; Nikolaev, Yury A; Nadezhdin, Kirill D; Gracheva, Elena O; Bagriantsev, Sviatoslav N; Sobolevsky, Alexander I |
Nature communications |
37117175 |
2023 Apr 28 |
| Structural basis for flagellin induced NAIP5 activation. |
Paidimuddala, Bhaskar; Cao, Jianhao; Zhang, Liman |
bioRxiv : the preprint server for biology |
37398004 |
2023 Jun 13 |
| Broadening access to cryoEM through centralized facilities. |
Zimanyi, Christina M; Kopylov, Mykhailo; Potter, Clinton S; Carragher, Bridget; Eng, Edward T |
Trends in biochemical sciences |
34823974 |
2022 Feb |
| Label-free visual proteomics: Coupling MS- and EM-based approaches in structural biology. |
Klykov, Oleg; Kopylov, Mykhailo; Carragher, Bridget; Heck, Albert J R; Noble, Alex J; Scheltema, Richard A |
Molecular cell |
35063097 |
2022 Jan 20 |
| Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. |
Chen, James; Wang, Qi; Malone, Brandon; Llewellyn, Eliza; Pechersky, Yakov; Maruthi, Kashyap; Eng, Ed T; Perry, Jason K; Campbell, Elizabeth A; Shaw, David E; Darst, Seth A |
Nature structural & molecular biology |
35260847 |
2022 Mar |
| Structures of an active type III-A CRISPR effector complex. |
Smith, Eric M; Ferrell, Sé; Tokars, Valerie L; Mondragón, Alfonso |
Structure (London, England : 1993) |
35714601 |
2022 Aug 04 |
| Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. |
Zhu, Jiaqiang; Huang, Wei; Zhao, Jing; Huynh, Loc; Taylor, Derek J; Harris, Michael E |
Nature communications |
36045135 |
2022 Aug 31 |
| Cryo-EM structure-based selection of computed ligand poses enables design of MTA-synergic PRMT5 inhibitors of better potency. |
Zhou, Wei; Yadav, Gaya P; Yang, Xiaozhi; Qin, Feng; Li, Chenglong; Jiang, Qiu-Xing |
Communications biology |
36192627 |
2022 Oct 03 |
| Electron crystallography of chiral and non-chiral small molecules. |
Zhou, Weijiang; Bammes, Benjamin; Mitchell, Patrick G; Betz, Kerry; Chiu, Wah |
Ultramicroscopy |
34695647 |
2022 01 |
| Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold. |
Fontana, Pietro; Dong, Ying; Pi, Xiong; Tong, Alexander B; Hecksel, Corey W; Wang, Longfei; Fu, Tian-Min; Bustamante, Carlos; Wu, Hao |
Science (New York, N.Y.) |
35679401 |
2022 Jun 10 |
| Metallic support films reduce optical heating in cryogenic correlative light and electron tomography. |
Dahlberg, Peter D; Perez, Davis; Hecksel, Corey W; Chiu, Wah; Moerner, W E |
Journal of structural biology |
36191745 |
2022 Dec |
| Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter. |
Thaker, Tarjani M; Mishra, Smriti; Zhou, Wenchang; Mohan, Michael; Tang, Qingyu; Faraldo-Goméz, José D; Mchaourab, Hassane S; Tomasiak, Thomas M |
Nature chemical biology |
34931066 |
2022 Feb |
| Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. |
Yang, Chun; Fujiwara, Rina; Kim, Hee Jong; Basnet, Pratik; Zhu, Yunye; Gorbea Colón, Jose J; Steimle, Stefan; Garcia, Benjamin A; Kaplan, Craig D; Murakami, Kenji |
Molecular cell |
35051353 |
2022 Feb 03 |
| Computational design of mechanically coupled axle-rotor protein assemblies. |
Courbet, A; Hansen, J; Hsia, Y; Bethel, N; Park, Y-J; Xu, C; Moyer, A; Boyken, S E; Ueda, G; Nattermann, U; Nagarajan, D; Silva, D-A; Sheffler, W; Quispe, J; Nord, A; King, N; Bradley, P; Veesler, D; Kollman, J; Baker, D |
Science (New York, N.Y.) |
35446645 |
2022 Apr 22 |
| BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. |
Xia, Min; David, Liron; Teater, Matt; Gutierrez, Johana; Wang, Xiang; Meydan, Cem; Lytle, Andrew; Slack, Graham W; Scott, David W; Morin, Ryan D; Onder, Ozlem; Elenitoba-Johnson, Kojo S J; Zamponi, Nahuel; Cerchietti, Leandro; Lu, Tianbao; Philippar, Ulri |
Cancer discovery |
35658124 |
2022 Aug 05 |
| Architecture of the linker-scaffold in the nuclear pore. |
Petrovic, Stefan; Samanta, Dipanjan; Perriches, Thibaud; Bley, Christopher J; Thierbach, Karsten; Brown, Bonnie; Nie, Si; Mobbs, George W; Stevens, Taylor A; Liu, Xiaoyu; Tomaleri, Giovani Pinton; Schaus, Lucas; Hoelz, André |
Science (New York, N.Y.) |
35679425 |
2022 Jun 10 |
| Superimmunity by pan-sarbecovirus nanobodies. |
Xiang, Yufei; Huang, Wei; Liu, Hejun; Sang, Zhe; Nambulli, Sham; Tubiana, Jérôme; Williams Jr, Kevin L; Duprex, W Paul; Schneidman-Duhovny, Dina; Wilson, Ian A; Taylor, Derek J; Shi, Yi |
Cell reports |
35738279 |
2022 Jun 28 |
| Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3. |
Fry, Michelle Y; Najdrová, Vladimíra; Maggiolo, Ailiena O; Saladi, Shyam M; Doležal, Pavel; Clemons Jr, William M |
Nature structural & molecular biology |
35851188 |
2022 Aug |
| Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria. |
Puskar, Ryan; Du Truong, Chloe; Swain, Kyle; Chowdhury, Saborni; Chan, Ka-Yi; Li, Shan; Cheng, Kai-Wen; Wang, Ting Yu; Poh, Yu-Ping; Mazor, Yuval; Liu, Haijun; Chou, Tsui-Fen; Nannenga, Brent L; Chiu, Po-Lin |
Nature communications |
36192412 |
2022 Oct 03 |
| Video Captioning Using Global-Local Representation. |
Yan, Liqi; Ma, Siqi; Wang, Qifan; Chen, Yingjie; Zhang, Xiangyu; Savakis, Andreas; Liu, Dongfang |
IEEE transactions on circuits and systems for video technology : a publication of the Circuits and Systems Society |
37215187 |
2022 Oct |
| 50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA. |
Laughlin, Zane T; Nandi, Suparno; Dey, Debayan; Zelinskaya, Natalia; Witek, Marta A; Srinivas, Pooja; Nguyen, Ha An; Kuiper, Emily G; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L |
Proceedings of the National Academy of Sciences of the United States of America |
35357969 |
2022 Apr 05 |
| Opening of glutamate receptor channel to subconductance levels. |
Yelshanskaya, Maria V; Patel, Dhilon S; Kottke, Christopher M; Kurnikova, Maria G; Sobolevsky, Alexander I |
Nature |
35444281 |
2022 May |
| Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes. |
Yu, You; Li, Shibai; Ser, Zheng; Kuang, Huihui; Than, Thane; Guan, Danying; Zhao, Xiaolan; Patel, Dinshaw J |
Proceedings of the National Academy of Sciences of the United States of America |
35648833 |
2022 Jun 07 |
| Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage. |
Finkelstein, Maxwell T; Parker Miller, Emma; Erdman, Molly C; Fera, Daniela |
Frontiers in immunology |
36225920 |
2022 |
| Structures of the nitrogenase complex prepared under catalytic turnover conditions. |
Rutledge, Hannah L; Cook, Brian D; Nguyen, Hoang P M; Herzik Jr, Mark A; Tezcan, F Akif |
Science (New York, N.Y.) |
35901182 |
2022 Aug 19 |
| Autoantibody mimicry of hormone action at the thyrotropin receptor. |
Faust, Bryan; Billesbølle, Christian B; Suomivuori, Carl-Mikael; Singh, Isha; Zhang, Kaihua; Hoppe, Nicholas; Pinto, Antonio F M; Diedrich, Jolene K; Muftuoglu, Yagmur; Szkudlinski, Mariusz W; Saghatelian, Alan; Dror, Ron O; Cheng, Yifan; Manglik, Aashish |
Nature |
35940205 |
2022 Sep |
| A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. |
Weidenbacher, Payton A-B; Sanyal, Mrinmoy; Friedland, Natalia; Tang, Shaogeng; Arunachalam, Prabhu S; Hu, Mengyun; Kumru, Ozan S; Morris, Mary Kate; Fontenot, Jane; Shirreff, Lisa; Do, Jonathan; Cheng, Ya-Chen; Vasudevan, Gayathri; Feinberg, Mark B; Villi |
bioRxiv : the preprint server for biology |
36597527 |
2022 Dec 26 |
| Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. |
Ren, Zhenning; Chhetri, Abhishek; Guan, Ziqiang; Suo, Yang; Yokoyama, Kenichi; Lee, Seok-Yong |
Nature structural & molecular biology |
35788183 |
2022 Jul |
| Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery. |
Mangala Prasad, Vidya; Blijleven, Jelle S; Smit, Jolanda M; Lee, Kelly K |
Nature communications |
35970990 |
2022 Aug 15 |
| Structural principles of B cell antigen receptor assembly. |
Dong, Ying; Pi, Xiong; Bartels-Burgahn, Frauke; Saltukoglu, Deniz; Liang, Zhuoyi; Yang, Jianying; Alt, Frederick W; Reth, Michael; Wu, Hao |
Nature |
36228656 |
2022 Dec |
| In situ cryo-FIB/SEM Specimen Preparation Using the Waffle Method. |
Klykov, Oleg; Bobe, Daija; Paraan, Mohammadreza; Johnston, Jake D; Potter, Clinton S; Carragher, Bridget; Kopylov, Mykhailo; Noble, Alex J |
Bio-protocol |
36618877 |
2022 Nov 05 |
| Development of CryoVR, a virtual reality training system for hands-on cryoEM operations. |
Dong, Jiahui; Li, Daoyi; Ozcan, Kadir; Wan, Dayu; Jiang, Wen; Chen, Yingjie |
Acta crystallographica. Section D, Structural biology |
35775989 |
2022 Jul 01 |
| Allosteric interactions prime androgen receptor dimerization and activation. |
Wasmuth, Elizabeth V; Broeck, Arnaud Vanden; LaClair, Justin R; Hoover, Elizabeth A; Lawrence, Kayla E; Paknejad, Navid; Pappas, Kyrie; Matthies, Doreen; Wang, Biran; Feng, Weiran; Watson, Philip A; Zinder, John C; Karthaus, Wouter R; de la Cruz, M Jason; |
Molecular cell |
35447082 |
2022 Jun 02 |
| Selective G protein signaling driven by substance P-neurokinin receptor dynamics. |
Harris, Julian A; Faust, Bryan; Gondin, Arisbel B; Dämgen, Marc André; Suomivuori, Carl-Mikael; Veldhuis, Nicholas A; Cheng, Yifan; Dror, Ron O; Thal, David M; Manglik, Aashish |
Nature chemical biology |
34711980 |
2022 Jan |
| Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. |
Tsai, Kaitlyn; Stojković, Vanja; Lee, D John; Young, Iris D; Szal, Teresa; Klepacki, Dorota; Vázquez-Laslop, Nora; Mankin, Alexander S; Fraser, James S; Fujimori, Danica Galonić |
Nature structural & molecular biology |
35165456 |
2022 Feb |
| Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. |
Kafai, Natasha M; Williamson, Lauren E; Binshtein, Elad; Sukupolvi-Petty, Soila; Gardner, Christina L; Liu, Jaclyn; Mackin, Samantha; Kim, Arthur S; Kose, Nurgun; Carnahan, Robert H; Jung, Ana; Droit, Lindsay; Reed, Douglas S; Handley, Scott A; Klimstra, |
The Journal of experimental medicine |
35297953 |
2022 Apr 04 |
| Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. |
Yu, Zanlin; Chen, Junliang; Takagi, Enzo; Wang, Feng; Saha, Bidisha; Liu, Xi; Joubert, Lydia-Marie; Gleason, Catherine E; Jin, Mingliang; Li, Chengmin; Nowotny, Carlos; Agard, David; Cheng, Yifan; Pearce, David |
The Journal of biological chemistry |
35926713 |
2022 Sep |
| A Robust Single-Particle Cryo-Electron Microscopy (cryo-EM) Processing Workflow with cryoSPARC, RELION, and Scipion. |
DiIorio, Megan C; Kulczyk, Arkadiusz W |
Journal of visualized experiments : JoVE |
35104261 |
2022 Jan 31 |
| Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer. |
Koo, Christopher W; Tucci, Frank J; He, Yuan; Rosenzweig, Amy C |
Science (New York, N.Y.) |
35298269 |
2022 Mar 18 |
| Structural mechanism of muscle nicotinic receptor desensitization and block by curare. |
Rahman, Md Mahfuzur; Basta, Tamara; Teng, Jinfeng; Lee, Myeongseon; Worrell, Brady T; Stowell, Michael H B; Hibbs, Ryan E |
Nature structural & molecular biology |
35301478 |
2022 Apr |
| Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. |
Kwon, Do Hoon; Zhang, Feng; Fedor, Justin G; Suo, Yang; Lee, Seok-Yong |
Nature communications |
35610228 |
2022 May 24 |
| Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody. |
Callaway, Heather M; Zyla, Dawid; Larrous, Florence; de Melo, Guilherme Dias; Hastie, Kathryn M; Avalos, Ruben Diaz; Agarwal, Alyssa; Corti, Davide; Bourhy, Hervé; Saphire, Erica Ollmann |
Science advances |
35714192 |
2022 Jun 17 |
| Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities. |
Zhu, Shaotong; Sridhar, Akshay; Teng, Jinfeng; Howard, Rebecca J; Lindahl, Erik; Hibbs, Ryan E |
Nature communications |
35933426 |
2022 Aug 06 |
| Structural basis for APE1 processing DNA damage in the nucleosome. |
Weaver, Tyler M; Hoitsma, Nicole M; Spencer, Jonah J; Gakhar, Lokesh; Schnicker, Nicholas J; Freudenthal, Bret D |
Nature communications |
36104361 |
2022 Sep 14 |
| Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP2. |
Yin, Ying; Zhang, Feng; Feng, Shasha; Butay, Kevin John; Borgnia, Mario J; Im, Wonpil; Lee, Seok-Yong |
Science (New York, N.Y.) |
36227998 |
2022 Oct 14 |
| Waffle Method: A general and flexible approach for improving throughput in FIB-milling. |
Kelley, Kotaro; Raczkowski, Ashleigh M; Klykov, Oleg; Jaroenlak, Pattana; Bobe, Daija; Kopylov, Mykhailo; Eng, Edward T; Bhabha, Gira; Potter, Clinton S; Carragher, Bridget; Noble, Alex J |
Nature communications |
35387991 |
2022 Apr 06 |
| Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide. |
Zhao, Yongxiang; Roy, Kasturi; Vidossich, Pietro; Cancedda, Laura; De Vivo, Marco; Forbush, Biff; Cao, Erhu |
Nature communications |
35585053 |
2022 May 18 |
| Improved mammalian retromer cryo-EM structures reveal a new assembly interface. |
Kendall, Amy K; Chandra, Mintu; Xie, Boyang; Wan, William; Jackson, Lauren P |
The Journal of biological chemistry |
36174678 |
2022 Nov |
| Three-dimensional structure-guided evolution of a ribosome with tethered subunits. |
Kim, Do Soon; Watkins, Andrew; Bidstrup, Erik; Lee, Joongoo; Topkar, Ved; Kofman, Camila; Schwarz, Kevin J; Liu, Yan; Pintilie, Grigore; Roney, Emily; Das, Rhiju; Jewett, Michael C |
Nature chemical biology |
35836020 |
2022 Sep |
| Development of an atmospheric plasma jet device for versatile treatment of electron microscope sample grids. |
Ahn, Eungjin; Tang, Tianyu; Kim, Byungchul; Lee, Hae June; Cho, Uhn-Soo |
The Journal of biological chemistry |
35248533 |
2022 Apr |
| The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation. |
Khandelwal, Nitesh Kumar; Millan, Cinthia R; Zangari, Samantha I; Avila, Samantha; Williams, Dewight; Thaker, Tarjani M; Tomasiak, Thomas M |
Nature communications |
35277487 |
2022 Mar 11 |
| Methotrexate recognition by the human reduced folate carrier SLC19A1. |
Wright, Nicholas J; Fedor, Justin G; Zhang, Han; Jeong, Pyeonghwa; Suo, Yang; Yoo, Jiho; Hong, Jiyong; Im, Wonpil; Lee, Seok-Yong |
Nature |
36071163 |
2022 Sep |
| Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. |
Cruz, Victor Emmanuel; Sekulski, Kamil; Peddada, Nagesh; Sailer, Carolin; Balasubramanian, Sahana; Weirich, Christine S; Stengel, Florian; Erzberger, Jan P |
Nature structural & molecular biology |
36482249 |
2022 Dec |
| Structure of the human cone photoreceptor cyclic nucleotide-gated channel. |
Zheng, Xiangdong; Hu, Zhengshan; Li, Huan; Yang, Jian |
Nature structural & molecular biology |
34969976 |
2022 Jan |
| Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. |
Liang, Wenguang G; Wijaya, Juwina; Wei, Hui; Noble, Alex J; Mancl, Jordan M; Mo, Swansea; Lee, David; Lin King, John V; Pan, Man; Liu, Chang; Koehler, Carla M; Zhao, Minglei; Potter, Clinton S; Carragher, Bridget; Li, Sheng; Tang, Wei-Jen |
Nature communications |
35383169 |
2022 Apr 05 |
| Structure of the human cation-chloride cotransport KCC1 in an outward-open state. |
Zhao, Yongxiang; Shen, Jiemin; Wang, Qinzhe; Ruiz Munevar, Manuel Jose; Vidossich, Pietro; De Vivo, Marco; Zhou, Ming; Cao, Erhu |
Proceedings of the National Academy of Sciences of the United States of America |
35759661 |
2022 Jul 05 |
| Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation. |
Abskharon, Romany; Sawaya, Michael R; Boyer, David R; Cao, Qin; Nguyen, Binh A; Cascio, Duilio; Eisenberg, David S |
Proceedings of the National Academy of Sciences of the United States of America |
35377792 |
2022 Apr 12 |
| Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. |
Li, Shanshan; Palo, Michael Z; Pintilie, Grigore; Zhang, Xiaojing; Su, Zhaoming; Kappel, Kalli; Chiu, Wah; Zhang, Kaiming; Das, Rhiju |
Proceedings of the National Academy of Sciences of the United States of America |
36067294 |
2022 Sep 13 |
| Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P2 and rapamycin. |
Gan, Ninghai; Han, Yan; Zeng, Weizhong; Wang, Yan; Xue, Jing; Jiang, Youxing |
Proceedings of the National Academy of Sciences of the United States of America |
35131932 |
2022 Feb 15 |
| Active conformation of the p97-p47 unfoldase complex. |
Xu, Yang; Han, Han; Cooney, Ian; Guo, Yuxuan; Moran, Noah G; Zuniga, Nathan R; Price, John C; Hill, Christopher P; Shen, Peter S |
Nature communications |
35552390 |
2022 May 12 |
| Conformational landscape of the yeast SAGA complex as revealed by cryo-EM. |
Vasyliuk, Diana; Felt, Joeseph; Zhong, Ellen D; Berger, Bonnie; Davis, Joseph H; Yip, Calvin K |
Scientific reports |
35853968 |
2022 Jul 19 |
| Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA. |
Bonilla, Steve L; Vicens, Quentin; Kieft, Jeffrey S |
Science advances |
36026457 |
2022 Aug 26 |
| Architecture of the human erythrocyte ankyrin-1 complex. |
Vallese, Francesca; Kim, Kookjoo; Yen, Laura Y; Johnston, Jake D; Noble, Alex J; Calì, Tito; Clarke, Oliver Biggs |
Nature structural & molecular biology |
35835865 |
2022 Jul |
| The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. |
Rangarajan, Erumbi S; Izard, Tina |
International journal of molecular sciences |
33440717 |
2021 Jan 11 |
| Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants. |
Moghadamchargari, Zahra; Shirzadeh, Mehdi; Liu, Chang; Schrecke, Samantha; Packianathan, Charles; Russell, David H; Zhao, Minglei; Laganowsky, Arthur |
Proceedings of the National Academy of Sciences of the United States of America |
33723061 |
2021 03 23 |
| Structure and function at the lipid-protein interface of a pentameric ligand-gated ion channel. |
Kumar, Pramod; Cymes, Gisela D; Grosman, Claudio |
Proceedings of the National Academy of Sciences of the United States of America |
34083441 |
2021 06 08 |
| Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. |
Nadezhdin, Kirill D; Neuberger, Arthur; Trofimov, Yuri A; Krylov, Nikolay A; Sinica, Viktor; Kupko, Nikita; Vlachova, Viktorie; Zakharian, Eleonora; Efremov, Roman G; Sobolevsky, Alexander I |
Nature structural & molecular biology |
34239124 |
2021 Jul |
| Structure and desensitization of AMPA receptor complexes with type II TARP γ5 and GSG1L. |
Klykov, Oleg; Gangwar, Shanti Pal; Yelshanskaya, Maria V; Yen, Laura; Sobolevsky, Alexander I |
Molecular cell |
34678168 |
2021 Dec 02 |
| Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution. |
Su, Zhaoming; Zhang, Kaiming; Kappel, Kalli; Li, Shanshan; Palo, Michael Z; Pintilie, Grigore D; Rangan, Ramya; Luo, Bingnan; Wei, Yuquan; Das, Rhiju; Chiu, Wah |
Nature |
34381213 |
2021 Aug |
| CorRelator: Interactive software for real-time high precision cryo-correlative light and electron microscopy. |
Yang, Jie E; Larson, Matthew R; Sibert, Bryan S; Shrum, Samantha; Wright, Elizabeth R |
Journal of structural biology |
33610654 |
2021 06 |
| Structural basis of long-range to short-range synaptic transition in NHEJ. |
Chen, Siyu; Lee, Linda; Naila, Tasmin; Fishbain, Susan; Wang, Annie; Tomkinson, Alan E; Lees-Miller, Susan P; He, Yuan |
Nature |
33854234 |
2021 May |
| TRPV3 expression and purification for structure determination by Cryo-EM. |
Neuberger, Arthur; Nadezhdin, Kirill D; Sobolevsky, Alexander I |
Methods in enzymology |
34059288 |
2021 |
| The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. |
Plenge, Per; Yang, Dongxue; Salomon, Kristine; Laursen, Louise; Kalenderoglou, Iris E; Newman, Amy H; Gouaux, Eric; Coleman, Jonathan A; Loland, Claus J |
Nature communications |
34417466 |
2021 08 20 |
| Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation. |
Rathinaswamy, Manoj K; Dalwadi, Udit; Fleming, Kaelin D; Adams, Carson; Stariha, Jordan T B; Pardon, Els; Baek, Minkyung; Vadas, Oscar; DiMaio, Frank; Steyaert, Jan; Hansen, Scott D; Yip, Calvin K; Burke, John E |
Science advances |
34452907 |
2021 Aug |
| Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. |
Scortecci, Jessica Fernandes; Molday, Laurie L; Curtis, Susan B; Garces, Fabian A; Panwar, Pankaj; Van Petegem, Filip; Molday, Robert S |
Nature communications |
34625547 |
2021 10 08 |
| Structural basis of chromatin regulation by histone variant H2A.Z. |
Lewis, Tyler S; Sokolova, Vladyslava; Jung, Harry; Ng, Honkit; Tan, Dongyan |
Nucleic acids research |
34643712 |
2021 11 08 |
| NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. |
Andreeva, Liudmila; David, Liron; Rawson, Shaun; Shen, Chen; Pasricha, Teerithveen; Pelegrin, Pablo; Wu, Hao |
Cell |
34861190 |
2021 Dec 22 |
| Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. |
Cerutti, Gabriele; Guo, Yicheng; Zhou, Tongqing; Gorman, Jason; Lee, Myungjin; Rapp, Micah; Reddem, Eswar R; Yu, Jian; Bahna, Fabiana; Bimela, Jude; Huang, Yaoxing; Katsamba, Phinikoula S; Liu, Lihong; Nair, Manoj S; Rawi, Reda; Olia, Adam S; Wang, Pengfe |
Cell host & microbe |
33789084 |
2021 05 12 |
| Extracellular cap domain is an essential component of the TRPV1 gating mechanism. |
Nadezhdin, Kirill D; Neuberger, Arthur; Nikolaev, Yury A; Murphy, Lyle A; Gracheva, Elena O; Bagriantsev, Sviatoslav N; Sobolevsky, Alexander I |
Nature communications |
33846324 |
2021 Apr 12 |
| Structures of telomerase at several steps of telomere repeat synthesis. |
He, Yao; Wang, Yaqiang; Liu, Baocheng; Helmling, Christina; Sušac, Lukas; Cheng, Ryan; Zhou, Z Hong; Feigon, Juli |
Nature |
33981033 |
2021 05 |
| Allosteric Inhibition of a Vesicular Glutamate Transporter by an Isoform-Specific Antibody. |
Eriksen, Jacob; Li, Fei; Stroud, Robert M; Edwards, Robert H |
Biochemistry |
34319067 |
2021 08 17 |
| Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation. |
Jette, Claudia A; Barnes, Christopher O; Kirk, Sharon M; Melillo, Bruno; Smith 3rd, Amos B; Bjorkman, Pamela J |
Nature communications |
33782388 |
2021 Mar 29 |
| Cryo-EM structure of a thermostable bacterial nanocompartment. |
Wiryaman, Timothy; Toor, Navtej |
IUCrJ |
33953921 |
2021 May 01 |
| Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment. |
Sharif, Humayun; Hollingsworth, L Robert; Griswold, Andrew R; Hsiao, Jeffrey C; Wang, Qinghui; Bachovchin, Daniel A; Wu, Hao |
Immunity |
34019797 |
2021 07 13 |
| Structural insight on assembly-line catalysis in terpene biosynthesis. |
Faylo, Jacque L; van Eeuwen, Trevor; Kim, Hee Jong; Gorbea Colón, Jose J; Garcia, Benjamin A; Murakami, Kenji; Christianson, David W |
Nature communications |
34108468 |
2021 06 09 |
| Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection. |
Chen, Peng; Zeng, Ji; Liu, Zheng; Thaker, Hatim; Wang, Siyu; Tian, Songhai; Zhang, Jie; Tao, Liang; Gutierrez, Craig B; Xing, Li; Gerhard, Ralf; Huang, Lan; Dong, Min; Jin, Rongsheng |
Nature communications |
34145250 |
2021 06 18 |
| Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. |
Lopez-Redondo, Maria; Fan, Shujie; Koide, Akiko; Koide, Shohei; Beckstein, Oliver; Stokes, David L |
The Journal of general physiology |
34254979 |
2021 08 02 |
| Architecture and assembly mechanism of native glycine receptors. |
Zhu, Hongtao; Gouaux, Eric |
Nature |
34555840 |
2021 Nov |
| Vascular KATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. |
Sung, Min Woo; Yang, Zhongying; Driggers, Camden M; Patton, Bruce L; Mostofian, Barmak; Russo, John D; Zuckerman, Daniel M; Shyng, Show-Ling |
Proceedings of the National Academy of Sciences of the United States of America |
34711681 |
2021 11 02 |
| Native Mass Spectrometry-Based Screening for Optimal Sample Preparation in Single-Particle Cryo-EM. |
Olinares, Paul Dominic B; Kang, Jin Young; Llewellyn, Eliza; Chiu, Courtney; Chen, James; Malone, Brandon; Saecker, Ruth M; Campbell, Elizabeth A; Darst, Seth A; Chait, Brian T |
Structure (London, England : 1993) |
33217329 |
2021 Feb 04 |
| D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. |
Gobeil, Sophie M-C; Janowska, Katarzyna; McDowell, Shana; Mansouri, Katayoun; Parks, Robert; Manne, Kartik; Stalls, Victoria; Kopp, Megan F; Henderson, Rory; Edwards, Robert J; Haynes, Barton F; Acharya, Priyamvada |
Cell reports |
33417835 |
2021 01 12 |
| Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. |
Williams, Wilton B; Meyerhoff, R Ryan; Edwards, R J; Li, Hui; Manne, Kartik; Nicely, Nathan I; Henderson, Rory; Zhou, Ye; Janowska, Katarzyna; Mansouri, Katayoun; Gobeil, Sophie; Evangelous, Tyler; Hora, Bhavna; Berry, Madison; Abuahmad, A Yousef; Sprenz, |
Cell |
34019795 |
2021 May 27 |
| Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair. |
van Eeuwen, Trevor; Shim, Yoonjung; Kim, Hee Jong; Zhao, Tingting; Basu, Shrabani; Garcia, Benjamin A; Kaplan, Craig D; Min, Jung-Hyun; Murakami, Kenji |
Nature communications |
34099686 |
2021 06 07 |
| Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole. |
Neuberger, Arthur; Nadezhdin, Kirill D; Sobolevsky, Alexander I |
Nature communications |
34725357 |
2021 11 01 |
| Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. |
Robert Hollingsworth, L; David, Liron; Li, Yang; Griswold, Andrew R; Ruan, Jianbin; Sharif, Humayun; Fontana, Pietro; Orth-He, Elizabeth L; Fu, Tian-Min; Bachovchin, Daniel A; Wu, Hao |
Nature communications |
33420033 |
2021 Jan 08 |
| Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. |
Grau, Daniel; Zhang, Yixiao; Lee, Chul-Hwan; Valencia-Sánchez, Marco; Zhang, Jenny; Wang, Miao; Holder, Marlene; Svetlov, Vladimir; Tan, Dongyan; Nudler, Evgeny; Reinberg, Danny; Walz, Thomas; Armache, Karim-Jean |
Nature communications |
33514705 |
2021 01 29 |
| Structure of the human Mediator-bound transcription preinitiation complex. |
Abdella, R; Talyzina, A; Chen, S; Inouye, C J; Tjian, R; He, Y |
Science (New York, N.Y.) |
33707221 |
2021 Apr 02 |
| DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. |
Hollingsworth, L Robert; Sharif, Humayun; Griswold, Andrew R; Fontana, Pietro; Mintseris, Julian; Dagbay, Kevin B; Paulo, Joao A; Gygi, Steven P; Bachovchin, Daniel A; Wu, Hao |
Nature |
33731932 |
2021 Apr |
| Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. |
Noviello, Colleen M; Gharpure, Anant; Mukhtasimova, Nuriya; Cabuco, Rico; Baxter, Leah; Borek, Dominika; Sine, Steven M; Hibbs, Ryan E |
Cell |
33735609 |
2021 04 15 |
| Heat-dependent opening of TRPV1 in the presence of capsaicin. |
Kwon, Do Hoon; Zhang, Feng; Suo, Yang; Bouvette, Jonathan; Borgnia, Mario J; Lee, Seok-Yong |
Nature structural & molecular biology |
34239123 |
2021 Jul |
| Structural basis for potassium transport in prokaryotes by KdpFABC. |
Sweet, Marie E; Larsen, Casper; Zhang, Xihui; Schlame, Michael; Pedersen, Bjørn P; Stokes, David L |
Proceedings of the National Academy of Sciences of the United States of America |
34272288 |
2021 07 20 |
| Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. |
Hu, Qi; Botuyan, Maria Victoria; Zhao, Debiao; Cui, Gaofeng; Mer, Elie; Mer, Georges |
Nature |
34321665 |
2021 08 |
| An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. |
Morgan, Christopher E; Zhang, Zhemin; Bonomo, Robert A; Yu, Edward W |
mBio |
35100868 |
2021 Feb 22 |
| Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses. |
Feldman, Jared; Bals, Julia; Altomare, Clara G; St Denis, Kerri; Lam, Evan C; Hauser, Blake M; Ronsard, Larance; Sangesland, Maya; Moreno, Thalia Bracamonte; Okonkwo, Vintus; Hartojo, Nathania; Balazs, Alejandro B; Bajic, Goran; Lingwood, Daniel; Schmidt, |
bioRxiv : the preprint server for biology |
33594359 |
2021 Jul 09 |
| Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. |
Malone, Brandon; Chen, James; Wang, Qi; Llewellyn, Eliza; Choi, Young Joo; Olinares, Paul Dominic B; Cao, Xinyun; Hernandez, Carolina; Eng, Edward T; Chait, Brian T; Shaw, David E; Landick, Robert; Darst, Seth A; Campbell, Elizabeth A |
bioRxiv : the preprint server for biology |
33758867 |
2021 Mar 14 |
| Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. |
Malone, Brandon; Chen, James; Wang, Qi; Llewellyn, Eliza; Choi, Young Joo; Olinares, Paul Dominic B; Cao, Xinyun; Hernandez, Carolina; Eng, Edward T; Chait, Brian T; Shaw, David E; Landick, Robert; Darst, Seth A; Campbell, Elizabeth A |
Proceedings of the National Academy of Sciences of the United States of America |
33883267 |
2021 May 11 |
| Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies. |
Cerutti, Gabriele; Rapp, Micah; Guo, Yicheng; Bahna, Fabiana; Bimela, Jude; Reddem, Eswar R; Yu, Jian; Wang, Pengfei; Liu, Lihong; Huang, Yaoxing; Ho, David D; Kwong, Peter D; Sheng, Zizhang; Shapiro, Lawrence |
Structure (London, England : 1993) |
34111408 |
2021 Jul 01 |
| Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60. |
Wang, Joseph Che-Yen; Chen, Lingling |
Scientific reports |
34285302 |
2021 07 20 |
| Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes. |
Sun, Dapeng; Sang, Zhe; Kim, Yong Joon; Xiang, Yufei; Cohen, Tomer; Belford, Anna K; Huet, Alexis; Conway, James F; Sun, Ji; Taylor, Derek J; Schneidman-Duhovny, Dina; Zhang, Cheng; Huang, Wei; Shi, Yi |
Nature communications |
34344900 |
2021 08 03 |
| HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases. |
Rathinaswamy, Manoj K; Fleming, Kaelin D; Dalwadi, Udit; Pardon, Els; Harris, Noah J; Yip, Calvin K; Steyaert, Jan; Burke, John E |
Structure (London, England : 1993) |
34348129 |
2021 12 02 |
| Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. |
Novikova, Irina V; Zhou, Mowei; Du, Chen; Parra, Marcelina; Kim, Doo Nam; VanAernum, Zachary L; Shaw, Jared B; Hellmann, Hanjo; Wysocki, Vicki H; Evans, James E |
ACS chemical biology |
34520180 |
2021 Nov 19 |
| AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. |
Caffrey, Brian; Zhu, Xing; Berezuk, Alison; Tuttle, Katharine; Chittori, Sagar; Subramaniam, Sriram |
The Journal of biological chemistry |
34520757 |
2021 10 |
| Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer. |
Hu, Wenxin; Zheng, Hongjin |
Communications biology |
34887516 |
2021 Dec 09 |
| Micropatterning Transmission Electron Microscopy Grids to Direct Cell Positioning within Whole-Cell Cryo-Electron Tomography Workflows. |
Sibert, Bryan S; Kim, Joseph Y; Yang, Jie E; Wright, Elizabeth R |
Journal of visualized experiments : JoVE |
34570100 |
2021 09 13 |
| Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes. |
Sun, Dapeng; Sang, Zhe; Kim, Yong Joon; Xiang, Yufei; Cohen, Tomer; Belford, Anna K; Huet, Alexis; Conway, James F; Sun, Ji; Taylor, Derek J; Schneidman-Duhovny, Dina; Zhang, Cheng; Huang, Wei; Shi, Yi |
bioRxiv : the preprint server for biology |
33758850 |
2021 Mar 10 |
| Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class. |
Rapp, Micah; Guo, Yicheng; Reddem, Eswar R; Yu, Jian; Liu, Lihong; Wang, Pengfei; Cerutti, Gabriele; Katsamba, Phinikoula; Bimela, Jude S; Bahna, Fabiana A; Mannepalli, Seetha M; Zhang, Baoshan; Kwong, Peter D; Huang, Yaoxing; Ho, David D; Shapiro, Lawren |
Cell reports |
33794145 |
2021 Apr 06 |
| Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. |
Gobeil, Sophie M-C; Janowska, Katarzyna; McDowell, Shana; Mansouri, Katayoun; Parks, Robert; Stalls, Victoria; Kopp, Megan F; Manne, Kartik; Li, Dapeng; Wiehe, Kevin; Saunders, Kevin O; Edwards, Robert J; Korber, Bette; Haynes, Barton F; Henderson, Rory; |
Science (New York, N.Y.) |
34168071 |
2021 Aug 06 |
| A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants. |
Schmitz, Aaron J; Turner, Jackson S; Liu, Zhuoming; Zhou, Julian Q; Aziati, Ishmael D; Chen, Rita E; Joshi, Astha; Bricker, Traci L; Darling, Tamarand L; Adelsberg, Daniel C; Altomare, Clara G; Alsoussi, Wafaa B; Case, James Brett; VanBlargan, Laura A; Le |
Immunity |
34464596 |
2021 Sep 14 |
| Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. |
Zhang, Kaiming; Zheludev, Ivan N; Hagey, Rachel J; Haslecker, Raphael; Hou, Yixuan J; Kretsch, Rachael; Pintilie, Grigore D; Rangan, Ramya; Kladwang, Wipapat; Li, Shanshan; Wu, Marie Teng-Pei; Pham, Edward A; Bernardin-Souibgui, Claire; Baric, Ralph S; Sh |
Nature structural & molecular biology |
34426697 |
2021 Sep |
| Mapping the catalytic conformations of an assembly-line polyketide synthase module. |
Cogan, Dillon P; Zhang, Kaiming; Li, Xiuyuan; Li, Shanshan; Pintilie, Grigore D; Roh, Soung-Hun; Craik, Charles S; Chiu, Wah; Khosla, Chaitan |
Science (New York, N.Y.) |
34735239 |
2021 Nov 05 |
| A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel. |
Liu, Chang; Reese, Rebecca; Vu, Simon; Rougé, Lionel; Shields, Shannon D; Kakiuchi-Kiyota, Satoko; Chen, Huifen; Johnson, Kevin; Shi, Yu Patrick; Chernov-Rogan, Tania; Greiner, Demi Maria Zabala; Kohli, Pawan Bir; Hackos, David; Brillantes, Bobby; Tam, Ch |
Neuron |
33152265 |
2021 01 20 |
| Structural Basis for Virulence Activation of Francisella tularensis. |
Travis, Brady A; Ramsey, Kathryn M; Prezioso, Samantha M; Tallo, Thomas; Wandzilak, Jamie M; Hsu, Allen; Borgnia, Mario; Bartesaghi, Alberto; Dove, Simon L; Brennan, Richard G; Schumacher, Maria A |
Molecular cell |
33217319 |
2021 01 07 |
| Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. |
Kato, Kazuki; Ahmad, Sadeem; Zhu, Zixiang; Young, Janet M; Mu, Xin; Park, Sehoon; Malik, Harmit S; Hur, Sun |
Molecular cell |
33373584 |
2021 02 04 |
| Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery. |
Herrera, Marco; Kim, Jeonghwan; Eygeris, Yulia; Jozic, Antony; Sahay, Gaurav |
Biomaterials science |
33586742 |
2021 Jun 15 |
| Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM. |
Shen, Betty W; Quispe, Joel D; Luyten, Yvette; McGough, Benjamin E; Morgan, Richard D; Stoddard, Barry L |
Structure (London, England : 1993) |
33826880 |
2021 Jun 03 |
| Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. |
Yu, Jie; Rao, Prashant; Clark, Sarah; Mitra, Jaba; Ha, Taekjip; Gouaux, Eric |
Nature |
33981040 |
2021 06 |
| Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy. |
Driggers, Camden M; Shyng, Show-Ling |
Methods in enzymology |
34099169 |
2021 |
| Structural and mechanistic basis for protein glutamylation by the kinase fold. |
Osinski, Adam; Black, Miles H; Pawłowski, Krzysztof; Chen, Zhe; Li, Yang; Tagliabracci, Vincent S |
Molecular cell |
34407442 |
2021 11 04 |
| Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography. |
Elferich, Johannes; Clark, Sarah; Ge, Jingpeng; Goehring, April; Matsui, Aya; Gouaux, Eric |
eLife |
34964715 |
2021 Dec 29 |
| Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy. |
Yang, Xiaoyong; Wang, Qinzhe; Cao, Erhu |
Nature communications |
32081947 |
2020 02 21 |
| Controlling the SARS-CoV-2 Spike Glycoprotein Conformation. |
Henderson, Rory; Edwards, Robert J; Mansouri, Katayoun; Janowska, Katarzyna; Stalls, Victoria; Gobeil, Sophie; Kopp, Megan; Hsu, Allen; Borgnia, Mario; Parks, Rob; Haynes, Barton F; Acharya, Priyamvada |
bioRxiv : the preprint server for biology |
32511343 |
2020 May 18 |
| Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. |
Liu, Lihong; Wang, Pengfei; Nair, Manoj S; Yu, Jian; Rapp, Micah; Wang, Qian; Luo, Yang; Chan, Jasper F-W; Sahi, Vincent; Figueroa, Amir; Guo, Xinzheng V; Cerutti, Gabriele; Bimela, Jude; Gorman, Jason; Zhou, Tongqing; Chen, Zhiwei; Yuen, Kwok-Yung; Kwong |
Nature |
32698192 |
2020 08 |
| Controlling the SARS-CoV-2 spike glycoprotein conformation. |
Henderson, Rory; Edwards, Robert J; Mansouri, Katayoun; Janowska, Katarzyna; Stalls, Victoria; Gobeil, Sophie M C; Kopp, Megan; Li, Dapeng; Parks, Rob; Hsu, Allen L; Borgnia, Mario J; Haynes, Barton F; Acharya, Priyamvada |
Nature structural & molecular biology |
32699321 |
2020 10 |
| Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. |
Durie, Clarissa L; Sheedlo, Michael J; Chung, Jeong Min; Byrne, Brenda G; Su, Min; Knight, Thomas; Swanson, Michele; Lacy, D Borden; Ohi, Melanie D |
eLife |
32876045 |
2020 Sep 02 |
| Light-coupled cryo-plunger for time-resolved cryo-EM. |
Yoder, Nate; Jalali-Yazdi, Farzad; Noreng, Sigrid; Houser, Alexandra; Baconguis, Isabelle; Gouaux, Eric |
Journal of structural biology |
32950604 |
2020 12 01 |
| Synthetic group A streptogramin antibiotics that overcome Vat resistance. |
Li, Qi; Pellegrino, Jenna; Lee, D John; Tran, Arthur A; Chaires, Hector A; Wang, Ruoxi; Park, Jesslyn E; Ji, Kaijie; Chow, David; Zhang, Na; Brilot, Axel F; Biel, Justin T; van Zundert, Gydo; Borrelli, Kenneth; Shinabarger, Dean; Wolfe, Cindy; Murray, Bev |
Nature |
32968273 |
2020 10 |
| Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch. |
Sobti, Meghna; Walshe, James L; Wu, Di; Ishmukhametov, Robert; Zeng, Yi C; Robinson, Carol V; Berry, Richard M; Stewart, Alastair G |
Nature communications |
32457314 |
2020 05 26 |
| Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. |
Zheng, Xiangdong; Fu, Ziao; Su, Deyuan; Zhang, Yuebin; Li, Minghui; Pan, Yaping; Li, Huan; Li, Shufang; Grassucci, Robert A; Ren, Zhenning; Hu, Zhengshan; Li, Xueming; Zhou, Ming; Li, Guohui; Frank, Joachim; Yang, Jian |
Nature structural & molecular biology |
32483338 |
2020 Jul |
| Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins. |
Rahman, Md Mahfuzur; Teng, Jinfeng; Worrell, Brady T; Noviello, Colleen M; Lee, Myeongseon; Karlin, Arthur; Stowell, Michael H B; Hibbs, Ryan E |
Neuron |
32275860 |
2020 06 17 |
| Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain. |
Vien, Thuy N; Wang, Jinliang; Ng, Leo C T; Cao, Erhu; DeCaen, Paul G |
Proceedings of the National Academy of Sciences of the United States of America |
32332171 |
2020 May 12 |
| The His-Gly motif of acid-sensing ion channels resides in a reentrant 'loop' implicated in gating and ion selectivity. |
Yoder, Nate; Gouaux, Eric |
eLife |
32496192 |
2020 06 04 |
| Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. |
Doran, Matthew H; Pavadai, Elumalai; Rynkiewicz, Michael J; Walklate, Jonathan; Bullitt, Esther; Moore, Jeffrey R; Regnier, Michael; Geeves, Michael A; Lehman, William |
Biophysical journal |
32730789 |
2020 08 18 |
| Chemical and structural investigation of the paroxetine-human serotonin transporter complex. |
Coleman, Jonathan A; Navratna, Vikas; Antermite, Daniele; Yang, Dongxue; Bull, James A; Gouaux, Eric |
eLife |
32618269 |
2020 07 03 |
| Structural basis of transcription-translation coupling. |
Wang, Chengyuan; Molodtsov, Vadim; Firlar, Emre; Kaelber, Jason T; Blaha, Gregor; Su, Min; Ebright, Richard H |
Science (New York, N.Y.) |
32820061 |
2020 09 11 |
| Shared structural mechanisms of general anaesthetics and benzodiazepines. |
Kim, Jeong Joo; Gharpure, Anant; Teng, Jinfeng; Zhuang, Yuxuan; Howard, Rebecca J; Zhu, Shaotong; Noviello, Colleen M; Walsh Jr, Richard M; Lindahl, Erik; Hibbs, Ryan E |
Nature |
32879488 |
2020 09 |
| The Structure of an AAV5-AAVR Complex at 2.5 Å Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors. |
Silveria, Mark A; Large, Edward E; Zane, Grant M; White, Tommi A; Chapman, Michael S |
Viruses |
33218165 |
2020 11 18 |
| Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex. |
Chen, James; Malone, Brandon; Llewellyn, Eliza; Grasso, Michael; Shelton, Patrick M M; Olinares, Paul Dominic B; Maruthi, Kashyap; Eng, Ed; Vatandaslar, Hasan; Chait, Brian T; Kapoor, Tarun; Darst, Seth A; Campbell, Elizabeth A |
bioRxiv : the preprint server for biology |
32676607 |
2020 Jul 13 |
| Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. |
Fromm, Simon A; Lawrence, Rosalie E; Hurley, James H |
Nature structural & molecular biology |
32868926 |
2020 11 |
| The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states. |
Santosh, Vishaka; Musayev, Faik N; Jaiswal, Rahul; Zárate-Pérez, Francisco; Vandewinkel, Bram; Dierckx, Caroline; Endicott, Molly; Sharifi, Kamyar; Dryden, Kelly; Henckaerts, Els; Escalante, Carlos R |
Nucleic acids research |
33270897 |
2020 12 16 |
| Computational Methods for Single-Particle Electron Cryomicroscopy. |
Singer, Amit; Sigworth, Fred J |
Annual review of biomedical data science |
34485850 |
2020 Jul |
| Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis. |
Herrera, Natalia G; Morano, Nicholas C; Celikgil, Alev; Georgiev, George I; Malonis, Ryan J; Lee, James H; Tong, Karen; Vergnolle, Olivia; Massimi, Aldo B; Yen, Laura Y; Noble, Alex J; Kopylov, Mykhailo; Bonanno, Jeffrey B; Garrett-Thomson, Sarah C; Hayes |
bioRxiv : the preprint server for biology |
32587972 |
2020 Jun 17 |
| Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex. |
Chen, James; Malone, Brandon; Llewellyn, Eliza; Grasso, Michael; Shelton, Patrick M M; Olinares, Paul Dominic B; Maruthi, Kashyap; Eng, Edward T; Vatandaslar, Hasan; Chait, Brian T; Kapoor, Tarun M; Darst, Seth A; Campbell, Elizabeth A |
Cell |
32783916 |
2020 Sep 17 |
| Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. |
Zhou, Tongqing; Tsybovsky, Yaroslav; Gorman, Jason; Rapp, Micah; Cerutti, Gabriele; Chuang, Gwo-Yu; Katsamba, Phinikoula S; Sampson, Jared M; Schön, Arne; Bimela, Jude; Boyington, Jeffrey C; Nazzari, Alexandra; Olia, Adam S; Shi, Wei; Sastry, Mallika; Ste |
Cell host & microbe |
33271067 |
2020 12 09 |
| Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery. |
Eygeris, Yulia; Patel, Siddharth; Jozic, Antony; Sahay, Gaurav |
Nano letters |
32375002 |
2020 06 10 |
| Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication. |
Unchwaniwala, Nuruddin; Zhan, Hong; Pennington, Janice; Horswill, Mark; den Boon, Johan A; Ahlquist, Paul |
Proceedings of the National Academy of Sciences of the United States of America |
32690711 |
2020 08 04 |
| Adeno-Associated Virus (AAV-DJ)-Cryo-EM Structure at 1.56 Å Resolution. |
Xie, Qing; Yoshioka, Craig K; Chapman, Michael S |
Viruses |
33092282 |
2020 10 20 |
| Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. |
Patel, Avinash B; Moore, Camille M; Greber, Basil J; Luo, Jie; Zukin, Stefan A; Ranish, Jeff; Nogales, Eva |
eLife |
31886770 |
2019 12 30 |
| The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. |
Gestaut, Daniel; Roh, Soung Hun; Ma, Boxue; Pintilie, Grigore; Joachimiak, Lukasz A; Leitner, Alexander; Walzthoeni, Thomas; Aebersold, Ruedi; Chiu, Wah; Frydman, Judith |
Cell |
30955883 |
2019 04 18 |
