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bioRxiv : the preprint server for biology |
39257821 |
bioRxiv |
2024 Dec 9 |
https://www.ncbi.nlm.nih.gov/pubmed/39257821 |
| Ligand identification in CryoEM and X-ray maps using deep learning. |
Karolczak J, Przybyłowska A, Szewczyk K, Taisner W, Heumann JM, Stowell MHB, Nowicki M, Brzezinski D |
Bioinformatics (Oxford, England) |
39700427 |
Bioinformatics |
2024 Dec 26 |
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Molecular cell |
35063097 |
Mol Cell |
2022 Jan 20 |
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Nature communications |
35387991 |
Nat Commun |
2022 Apr 6 |
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Sawh-Gopal A, Ishemgulova A, Chua EYD, Aragon MF, Mendez JH, Eng ET, Noble AJ |
Journal of visualized experiments : JoVE |
38108412 |
J Vis Exp |
2023 Dec 1 |
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Annu Rev Biochem |
2022 Jun 21 |
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Bio-protocol |
36618877 |
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2022 Nov 5 |
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Nature structural & molecular biology |
35835865 |
Nat Struct Mol Biol |
2022 Jul |
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PloS one |
37352230 |
PLoS One |
2023 |
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Nature methods |
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Nat Methods |
2023 Oct |
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Kim JY, Yang JE, Mitchell JW, English LA, Yang SZ, Tenpas T, Dent EW, Wildonger J, Wright ER |
bioRxiv : the preprint server for biology |
37502991 |
bioRxiv |
2023 Jul 11 |
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Kim JY, Yang JE, Mitchell JW, English LA, Yang SZ, Tenpas T, Dent EW, Wildonger J, Wright ER |
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada |
37966978 |
Microsc Microanal |
2023 Dec 21 |
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Sibert BS, Kim JY, Yang JE, Wright ER |
Journal of visualized experiments : JoVE |
34570100 |
J Vis Exp |
2021 Sep 13 |
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Sanchez JC, Baumgardt JK, Wright ER |
Bio-protocol |
39100595 |
Bio Protoc |
2024 Jul 20 |
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Journal of structural biology |
33610654 |
J Struct Biol |
2021 Jun |
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Yang J, Vrbovská V, Franke T, Sibert B, Larson M, Hall A, Rigort A, Mitchels J, Wright ER |
bioRxiv : the preprint server for biology |
37502891 |
bioRxiv |
2023 Jul 12 |
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mBio |
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mBio |
2024 Jan 16 |
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Pierson JA, Yang JE, Wright ER |
Current opinion in structural biology |
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Curr Opin Struct Biol |
2024 Dec |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Sep 19 |
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Nature communications |
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Nat Commun |
2024 Dec 6 |
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Yang JE, Mitchell JM, Bingman CA, Mosher DF, Wright ER |
bioRxiv : the preprint server for biology |
39416224 |
bioRxiv |
2024 Oct 11 |
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Bio-protocol |
39959285 |
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mBio |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2023 Dec 5 |
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Parrell D, Olson J, Lemke RA, Donohue TJ, Wright ER |
Biomolecules |
39199393 |
Biomolecules |
2024 Aug 14 |
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microPublication biology |
38725941 |
MicroPubl Biol |
2024 |
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Nature communications |
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Nat Commun |
2024 Jul 14 |
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bioRxiv : the preprint server for biology |
37503001 |
bioRxiv |
2023 Jul 10 |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2025 Feb 4 |
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bioRxiv : the preprint server for biology |
37577490 |
bioRxiv |
2024 Sep 5 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Mar 27 |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2024 Jul 2 |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2024 Oct 22 |
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Structure (London, England : 1993) |
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Structure |
2025 Feb 6 |
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bioRxiv : the preprint server for biology |
37961228 |
bioRxiv |
2025 Feb 23 |
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bioRxiv : the preprint server for biology |
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2024 Oct 22 |
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Nat Commun |
2022 Oct 3 |
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Structure (London, England : 1993) |
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Structure |
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Nature communications |
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Nat Commun |
2023 Mar 2 |
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Hussein A, Fan S, Lopez-Redondo M, Kenney I, Zhang X, Beckstein O, Stokes DL |
bioRxiv : the preprint server for biology |
36865113 |
bioRxiv |
2023 Jul 31 |
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Molecular cell |
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Mol Cell |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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IUCrJ |
2021 May 1 |
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Structure (London, England : 1993) |
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Structure |
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Nature communications |
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Nat Commun |
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Nature communications |
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Nat Commun |
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British journal of pharmacology |
38454578 |
Br J Pharmacol |
2024 Jul |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Mar 6 |
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Immunity |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Nature |
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Nature |
2023 Oct |
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bioRxiv : the preprint server for biology |
37732203 |
bioRxiv |
2024 Feb 1 |
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Nature communications |
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Nat Commun |
2023 May 27 |
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Proceedings of the National Academy of Sciences of the United States of America |
37307464 |
Proc Natl Acad Sci U S A |
2023 Jun 20 |
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Proceedings of the National Academy of Sciences of the United States of America |
37436958 |
Proc Natl Acad Sci U S A |
2023 Jul 18 |
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Langeberg CJ, Kieft JS |
Nucleic acids research |
37791881 |
Nucleic Acids Res |
2023 Nov 10 |
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Cell reports |
35738279 |
Cell Rep |
2022 Jun 28 |
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Dalton MP, Cheng MH, Bahar I, Coleman JA |
eLife |
38517752 |
Elife |
2024 Mar 22 |
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| Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication. |
Unchwaniwala N, Zhan H, Pennington J, Horswill M, den Boon JA, Ahlquist P |
Proceedings of the National Academy of Sciences of the United States of America |
32690711 |
Proc Natl Acad Sci U S A |
2020 Aug 4 |
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eLife |
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Elife |
2020 Jul 3 |
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Nano letters |
32375002 |
Nano Lett |
2020 Jun 10 |
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| Structural mechanism of muscle nicotinic receptor desensitization and block by curare. |
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Nature structural & molecular biology |
35301478 |
Nat Struct Mol Biol |
2022 Apr |
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| Cryo-EM reveals the molecular basis oflaminin polymerization and LN-lamininopathies. |
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Nature communications |
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Nat Commun |
2023 Jan 19 |
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Nature communications |
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Nat Commun |
2021 Jan 29 |
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Nature communications |
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Nat Commun |
2021 Jan 8 |
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Mangala Prasad V, Blijleven JS, Smit JM, Lee KK |
Nature communications |
35970990 |
Nat Commun |
2022 Aug 15 |
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Koo CW, Tucci FJ, He Y, Rosenzweig AC |
Science (New York, N.Y.) |
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Science |
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Science (New York, N.Y.) |
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Science |
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Nature |
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Nature |
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Nature communications |
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Nat Commun |
2021 Nov 1 |
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Nucleic acids research |
34643712 |
Nucleic Acids Res |
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Nature |
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Nature |
2024 Jan |
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Nature communications |
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Nat Commun |
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bioRxiv : the preprint server for biology |
37790392 |
bioRxiv |
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Nature communications |
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Nat Commun |
2023 Oct 11 |
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Gangwar SP, Yelshanskaya MV, Aktolun M, Yen LY, Newton TP, Strømgaard K, Kurnikova MG, Sobolevsky AI |
Nature communications |
39592599 |
Nat Commun |
2024 Nov 26 |
https://www.ncbi.nlm.nih.gov/pubmed/39592599 |
| AI-Based Discovery and CryoEM Structural Elucidation of a K(ATP) Channel Pharmacochaperone. |
ElSheikh A, Driggers CM, Truong HH, Yang Z, Allen J, Henriksen N, Walczewska-Szewc K, Shyng SL |
bioRxiv : the preprint server for biology |
39282384 |
bioRxiv |
2025 Feb 7 |
https://www.ncbi.nlm.nih.gov/pubmed/39282384 |
| Structural basis for transcription activation through cooperative recruitment of MntR. |
Shi H, Fu Y, Kodyte V, Andreas A, Sachla AJ, Miller K, Shrestha R, Helmann JD, Glasfeld A, Ahuja S |
Research square |
39070638 |
Res Sq |
2024 Jul 15 |
https://www.ncbi.nlm.nih.gov/pubmed/39070638 |
| Multi-organ structural homogeneity of amyloid fibrils in ATTRv-T60A amyloidosis patients, revealed by Cryo-EM. |
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bioRxiv : the preprint server for biology |
38798519 |
bioRxiv |
2024 May 14 |
https://www.ncbi.nlm.nih.gov/pubmed/38798519 |
| Structure of the human dopamine transporter and mechanisms of inhibition. |
Srivastava DK, Navratna V, Tosh DK, Chinn A, Sk MF, Tajkhorshid E, Jacobson KA, Gouaux E |
Nature |
39112705 |
Nature |
2024 Aug |
https://www.ncbi.nlm.nih.gov/pubmed/39112705 |
| Multi-layered heterochromatin interaction as a switch for DIM2-mediated DNA methylation. |
Shao Z, Lu J, Khudaverdyan N, Song J |
Nature communications |
39122718 |
Nat Commun |
2024 Aug 9 |
https://www.ncbi.nlm.nih.gov/pubmed/39122718 |
| Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation. |
Burke SM, Avstrikova M, Noviello CM, Mukhtasimova N, Changeux JP, Thakur GA, Sine SM, Cecchini M, Hibbs RE |
Cell |
38382524 |
Cell |
2024 Feb 29 |
https://www.ncbi.nlm.nih.gov/pubmed/38382524 |
| Human calpain-3 and its structural plasticity: dissociation of a homohexamer into dimers on binding titin. |
Ye Q, Henrickson A, Demeler B, Serrão VHB, Davies PL |
bioRxiv : the preprint server for biology |
38464089 |
bioRxiv |
2024 Mar 3 |
https://www.ncbi.nlm.nih.gov/pubmed/38464089 |
| Dynamic fibrillar assembly of αB-crystallin induced by perturbation of the conserved NT-IXI motif resolved by cryo-EM. |
McFarland R, Reichow S |
bioRxiv : the preprint server for biology |
38585788 |
bioRxiv |
2024 Mar 27 |
https://www.ncbi.nlm.nih.gov/pubmed/38585788 |
| Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain. |
Wu W, Kumar P, Brautigam CA, Tso SC, Baniasadi HR, Kober DL, Gilles-Gonzalez MA |
bioRxiv : the preprint server for biology |
39091779 |
bioRxiv |
2024 Jul 24 |
https://www.ncbi.nlm.nih.gov/pubmed/39091779 |
| Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization. |
Lanning S, Aguilar-Hernández N, Serrão VHB, López T, O'Rourke SM, Lentz A, Ricemeyer L, Espinosa R, López S, Arias CF, DuBois RM |
bioRxiv : the preprint server for biology |
39314284 |
bioRxiv |
2024 Sep 14 |
https://www.ncbi.nlm.nih.gov/pubmed/39314284 |
| Structural insights into subunit-dependent functional regulation in epithelial sodium channels. |
Houser A, Baconguis I |
Structure (London, England : 1993) |
39667931 |
Structure |
2025 Feb 6 |
https://www.ncbi.nlm.nih.gov/pubmed/39667931 |
| Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. |
Baier AS, Gioacchini N, Eek P, Leith EM, Tan S, Peterson CL |
eLife |
38809771 |
Elife |
2024 May 29 |
https://www.ncbi.nlm.nih.gov/pubmed/38809771 |
| Structural basis of TFIIIC-dependent RNA Polymerase III transcription initiation. |
Talyzina A, Han Y, Banerjee C, Fishbain S, Reyes A, Vafabakhsh R, He Y |
bioRxiv : the preprint server for biology |
37292922 |
bioRxiv |
2023 May 16 |
https://www.ncbi.nlm.nih.gov/pubmed/37292922 |
| Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. |
Baier AS, Gioacchini N, Eek P, Tan S, Peterson CL |
Research square |
37546845 |
Res Sq |
2023 Jul 28 |
https://www.ncbi.nlm.nih.gov/pubmed/37546845 |
| Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. |
Huang Y, Kumar S, Lee J, Lü W, Du J |
Nature structural & molecular biology |
38773335 |
Nat Struct Mol Biol |
2024 Oct |
https://www.ncbi.nlm.nih.gov/pubmed/38773335 |
| A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion. |
Nguyen QH, Lai CHR, Norris MJ, Ng D, Shah M, Lai CC, Isenman DE, Moraes TF |
bioRxiv : the preprint server for biology |
39484374 |
bioRxiv |
2024 Oct 21 |
https://www.ncbi.nlm.nih.gov/pubmed/39484374 |
| Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket. |
Shi H, Ditter IA, Oken AC, Mansoor SE |
Science advances |
39823330 |
Sci Adv |
2025 Jan 17 |
https://www.ncbi.nlm.nih.gov/pubmed/39823330 |
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Herrera M, Kim J, Eygeris Y, Jozic A, Sahay G |
Biomaterials science |
33586742 |
Biomater Sci |
2021 Jun 15 |
https://www.ncbi.nlm.nih.gov/pubmed/33586742 |
| Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. |
Noviello CM, Gharpure A, Mukhtasimova N, Cabuco R, Baxter L, Borek D, Sine SM, Hibbs RE |
Cell |
33735609 |
Cell |
2021 Apr 15 |
https://www.ncbi.nlm.nih.gov/pubmed/33735609 |
| Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation. |
Jette CA, Barnes CO, Kirk SM, Melillo B, Smith AB 3rd, Bjorkman PJ |
Nature communications |
33782388 |
Nat Commun |
2021 Mar 29 |
https://www.ncbi.nlm.nih.gov/pubmed/33782388 |
| Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. |
Yu J, Rao P, Clark S, Mitra J, Ha T, Gouaux E |
Nature |
33981040 |
Nature |
2021 Jun |
https://www.ncbi.nlm.nih.gov/pubmed/33981040 |
| TRPV3 expression and purification for structure determination by Cryo-EM. |
Neuberger A, Nadezhdin KD, Sobolevsky AI |
Methods in enzymology |
34059288 |
Methods Enzymol |
2021 |
https://www.ncbi.nlm.nih.gov/pubmed/34059288 |
| Structural Basis for Virulence Activation of Francisella tularensis. |
Travis BA, Ramsey KM, Prezioso SM, Tallo T, Wandzilak JM, Hsu A, Borgnia M, Bartesaghi A, Dove SL, Brennan RG, Schumacher MA |
Molecular cell |
33217319 |
Mol Cell |
2021 Jan 7 |
https://www.ncbi.nlm.nih.gov/pubmed/33217319 |
| Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. |
Novikova IV, Zhou M, Du C, Parra M, Kim DN, VanAernum ZL, Shaw JB, Hellmann H, Wysocki VH, Evans JE |
ACS chemical biology |
34520180 |
ACS Chem Biol |
2021 Nov 19 |
https://www.ncbi.nlm.nih.gov/pubmed/34520180 |
| Structural and mechanistic basis for protein glutamylation by the kinase fold. |
Osinski A, Black MH, Pawłowski K, Chen Z, Li Y, Tagliabracci VS |
Molecular cell |
34407442 |
Mol Cell |
2021 Nov 4 |
https://www.ncbi.nlm.nih.gov/pubmed/34407442 |
| The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. |
Plenge P, Yang D, Salomon K, Laursen L, Kalenderoglou IE, Newman AH, Gouaux E, Coleman JA, Loland CJ |
Nature communications |
34417466 |
Nat Commun |
2021 Aug 20 |
https://www.ncbi.nlm.nih.gov/pubmed/34417466 |
| AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. |
Caffrey B, Zhu X, Berezuk A, Tuttle K, Chittori S, Subramaniam S |
The Journal of biological chemistry |
34520757 |
J Biol Chem |
2021 Oct |
https://www.ncbi.nlm.nih.gov/pubmed/34520757 |
| A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel. |
Liu C, Reese R, Vu S, Rougé L, Shields SD, Kakiuchi-Kiyota S, Chen H, Johnson K, Shi YP, Chernov-Rogan T, Greiner DMZ, Kohli PB, Hackos D, Brillantes B, Tam C, Li T, Wang J, Safina B, Magnuson S, Volgraf M, Payandeh J, Zheng J, Rohou A, Chen J |
Neuron |
33152265 |
Neuron |
2021 Jan 20 |
https://www.ncbi.nlm.nih.gov/pubmed/33152265 |
| Adeno-Associated Virus (AAV-DJ)-Cryo-EM Structure at 1.56 Å Resolution. |
Xie Q, Yoshioka CK, Chapman MS |
Viruses |
33092282 |
Viruses |
2020 Oct 20 |
https://www.ncbi.nlm.nih.gov/pubmed/33092282 |
| The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation. |
Khandelwal NK, Millan CR, Zangari SI, Avila S, Williams D, Thaker TM, Tomasiak TM |
Nature communications |
35277487 |
Nat Commun |
2022 Mar 11 |
https://www.ncbi.nlm.nih.gov/pubmed/35277487 |
| Computational design of mechanically coupled axle-rotor protein assemblies. |
Courbet A, Hansen J, Hsia Y, Bethel N, Park YJ, Xu C, Moyer A, Boyken SE, Ueda G, Nattermann U, Nagarajan D, Silva DA, Sheffler W, Quispe J, Nord A, King N, Bradley P, Veesler D, Kollman J, Baker D |
Science (New York, N.Y.) |
35446645 |
Science |
2022 Apr 22 |
https://www.ncbi.nlm.nih.gov/pubmed/35446645 |
| Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide. |
Zhao Y, Roy K, Vidossich P, Cancedda L, De Vivo M, Forbush B, Cao E |
Nature communications |
35585053 |
Nat Commun |
2022 May 18 |
https://www.ncbi.nlm.nih.gov/pubmed/35585053 |
| Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer. |
Hu W, Zheng H |
Communications biology |
34887516 |
Commun Biol |
2021 Dec 9 |
https://www.ncbi.nlm.nih.gov/pubmed/34887516 |
| Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter. |
Thaker TM, Mishra S, Zhou W, Mohan M, Tang Q, Faraldo-Goméz JD, Mchaourab HS, Tomasiak TM |
Nature chemical biology |
34931066 |
Nat Chem Biol |
2022 Feb |
https://www.ncbi.nlm.nih.gov/pubmed/34931066 |
| Cryo-EM Structure of AAV2 Rep68 bound to integration site AAVS1: Insights into the mechanism of DNA melting. |
Jaiswal R, Santosh V, Braud B, Washington A, Escalante CR |
bioRxiv : the preprint server for biology |
38617369 |
bioRxiv |
2024 Apr 2 |
https://www.ncbi.nlm.nih.gov/pubmed/38617369 |
| Cryo-EM analysis of Pseudomonas phage Pa193 structural components. |
Iglesias SM, Hou CD, Reid J, Schauer E, Geier R, Soriaga A, Sim L, Gao L, Whitelegge J, Kyme P, Birx D, Lemire S, Cingolani G |
Communications biology |
39370451 |
Commun Biol |
2024 Oct 6 |
https://www.ncbi.nlm.nih.gov/pubmed/39370451 |
| NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. |
Andreeva L, David L, Rawson S, Shen C, Pasricha T, Pelegrin P, Wu H |
Cell |
34861190 |
Cell |
2021 Dec 22 |
https://www.ncbi.nlm.nih.gov/pubmed/34861190 |
| Gating choreography and mechanism of the human proton-activated chloride channel ASOR. |
Wang C, Polovitskaya MM, Delgado BD, Jentsch TJ, Long SB |
Science advances |
35108041 |
Sci Adv |
2022 Feb 4 |
https://www.ncbi.nlm.nih.gov/pubmed/35108041 |
| Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3. |
Fry MY, Najdrová V, Maggiolo AO, Saladi SM, Doležal P, Clemons WM Jr |
Nature structural & molecular biology |
35851188 |
Nat Struct Mol Biol |
2022 Aug |
https://www.ncbi.nlm.nih.gov/pubmed/35851188 |
| Conformational landscape of the yeast SAGA complex as revealed by cryo-EM. |
Vasyliuk D, Felt J, Zhong ED, Berger B, Davis JH, Yip CK |
Scientific reports |
35853968 |
Sci Rep |
2022 Jul 19 |
https://www.ncbi.nlm.nih.gov/pubmed/35853968 |
| The promise of cryo-EM to explore RNA structural dynamics. |
Bonilla SL, Kieft JS |
Journal of molecular biology |
36049551 |
J Mol Biol |
2022 Sep 30 |
https://www.ncbi.nlm.nih.gov/pubmed/36049551 |
| Transient Prenyltransferase-Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase. |
Faylo JL, van Eeuwen T, Gupta K, Murakami K, Christianson DW |
Biochemistry |
36227241 |
Biochemistry |
2022 Nov 1 |
https://www.ncbi.nlm.nih.gov/pubmed/36227241 |
| Structural principles of B cell antigen receptor assembly. |
Dong Y, Pi X, Bartels-Burgahn F, Saltukoglu D, Liang Z, Yang J, Alt FW, Reth M, Wu H |
Nature |
36228656 |
Nature |
2022 Dec |
https://www.ncbi.nlm.nih.gov/pubmed/36228656 |
| TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. |
Kwon DH, Zhang F, McCray BA, Feng S, Kumar M, Sullivan JM, Im W, Sumner CJ, Lee SY |
Nature communications |
37353484 |
Nat Commun |
2023 Jun 23 |
https://www.ncbi.nlm.nih.gov/pubmed/37353484 |
| Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation. |
Talyzina A, Han Y, Banerjee C, Fishbain S, Reyes A, Vafabakhsh R, He Y |
Molecular cell |
37402369 |
Mol Cell |
2023 Aug 3 |
https://www.ncbi.nlm.nih.gov/pubmed/37402369 |
| Focusing antibody responses to the fusion peptide in rhesus macaques. |
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB |
bioRxiv : the preprint server for biology |
37425865 |
bioRxiv |
2023 Jun 27 |
https://www.ncbi.nlm.nih.gov/pubmed/37425865 |
| Structural basis for DNA proofreading. |
Buchel G, Nayak AR, Herbine K, Sarfallah A, Sokolova VO, Zamudio-Ochoa A, Temiakov D |
Nature communications |
38151585 |
Nat Commun |
2023 Dec 27 |
https://www.ncbi.nlm.nih.gov/pubmed/38151585 |
| High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology. |
Zhang Z, Tringides ML, Morgan CE, Miyagi M, Mears JA, Hoppel CL, Yu EW |
Molecular & cellular proteomics : MCP |
37839702 |
Mol Cell Proteomics |
2023 Dec |
https://www.ncbi.nlm.nih.gov/pubmed/37839702 |
| Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin. |
Neuberger A, Trofimov YA, Yelshanskaya MV, Khau J, Nadezhdin KD, Khosrof LS, Krylov NA, Efremov RG, Sobolevsky AI |
Nature communications |
37532722 |
Nat Commun |
2023 Aug 2 |
https://www.ncbi.nlm.nih.gov/pubmed/37532722 |
| Energy coupling and stoichiometry of Zn(2+)/H(+) antiport by the prokaryotic cation diffusion facilitator YiiP. |
Hussein A, Fan S, Lopez-Redondo M, Kenney I, Zhang X, Beckstein O, Stokes DL |
eLife |
37906094 |
Elife |
2023 Oct 31 |
https://www.ncbi.nlm.nih.gov/pubmed/37906094 |
| Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. |
Iglesias SM, Lokareddy RK, Yang R, Li F, Yeggoni DP, David Hou CF, Leroux MN, Cortines JR, Leavitt JC, Bird M, Casjens SR, White S, Teschke CM, Cingolani G |
Journal of molecular biology |
37952769 |
J Mol Biol |
2023 Dec 15 |
https://www.ncbi.nlm.nih.gov/pubmed/37952769 |
| Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. |
Alexander JAN, Worrall LJ, Hu J, Vuckovic M, Satishkumar N, Poon R, Sobhanifar S, Rosell FI, Jenkins J, Chiang D, Mosimann WA, Chambers HF, Paetzel M, Chatterjee SS, Strynadka NCJ |
Nature |
36599987 |
Nature |
2023 Jan |
https://www.ncbi.nlm.nih.gov/pubmed/36599987 |
| Inhibition of the proton-activated chloride channel PAC by PIP(2). |
Mihaljević L, Ruan Z, Osei-Owusu J, Lü W, Qiu Z |
eLife |
36633397 |
Elife |
2023 Jan 12 |
https://www.ncbi.nlm.nih.gov/pubmed/36633397 |
| Mechanism of Ca(2+) transport by ferroportin. |
Shen J, Wilbon AS, Zhou M, Pan Y |
eLife |
36648329 |
Elife |
2023 Jan 17 |
https://www.ncbi.nlm.nih.gov/pubmed/36648329 |
| Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1. |
Srivastava D, Yadav RP, Singh S, Boyd K, Artemyev NO |
Structure (London, England : 1993) |
36657440 |
Structure |
2023 Mar 2 |
https://www.ncbi.nlm.nih.gov/pubmed/36657440 |
| Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor. |
Childers KC, Avery NG, Estrada Alamo KA, Davulcu O, Haynes RM, Lollar P, Doering CB, Coxon CH, Spiegel PC |
Blood |
37192299 |
Blood |
2023 Jul 13 |
https://www.ncbi.nlm.nih.gov/pubmed/37192299 |
| Sensory specializations drive octopus and squid behaviour. |
Kang G, Allard CAH, Valencia-Montoya WA, van Giesen L, Kim JJ, Kilian PB, Bai X, Bellono NW, Hibbs RE |
Nature |
37045917 |
Nature |
2023 Apr |
https://www.ncbi.nlm.nih.gov/pubmed/37045917 |
| Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme. |
Wu CG, Balakrishnan VK, Parihar PS, Konovolov K, Chen YC, Merrill RA, Wei H, Carragher B, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Honkanen R, Chung WK, Suzuki A, Strack S, Huang X, Xing Y |
bioRxiv : the preprint server for biology |
37066309 |
bioRxiv |
2023 Apr 5 |
https://www.ncbi.nlm.nih.gov/pubmed/37066309 |
| Structure and assembly of a bacterial gasdermin pore. |
Johnson AG, Mayer ML, Schaefer SL, McNamara-Bordewick NK, Hummer G, Kranzusch PJ |
bioRxiv : the preprint server for biology |
37131678 |
bioRxiv |
2023 Oct 26 |
https://www.ncbi.nlm.nih.gov/pubmed/37131678 |
| Caenorhabditis elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. |
Consalvo CD, Aderounmu AM, Donelick HM, Aruscavage PJ, Eckert DM, Shen PS, Bass BL |
eLife |
38747717 |
Elife |
2024 May 15 |
https://www.ncbi.nlm.nih.gov/pubmed/38747717 |
| mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies. |
Xie Z, Lin YC, Steichen JM, Ozorowski G, Kratochvil S, Ray R, Torres JL, Liguori A, Kalyuzhniy O, Wang X, Warner JE, Weldon SR, Dale GA, Kirsch KH, Nair U, Baboo S, Georgeson E, Adachi Y, Kubitz M, Jackson AM, Richey ST, Volk RM, Lee JH, Diedrich JK, Prum T, Falcone S, Himansu S, Carfi A, Yates JR 3rd, Paulson JC, Sok D, Ward AB, Schief WR, Batista FD |
Science (New York, N.Y.) |
38753770 |
Science |
2024 May 17 |
https://www.ncbi.nlm.nih.gov/pubmed/38753770 |
| Structure and assembly of a bacterial gasdermin pore. |
Johnson AG, Mayer ML, Schaefer SL, McNamara-Bordewick NK, Hummer G, Kranzusch PJ |
Nature |
38509367 |
Nature |
2024 Apr |
https://www.ncbi.nlm.nih.gov/pubmed/38509367 |
| A suite of designed protein cages using machine learning and protein fragment-based protocols. |
Meador K, Castells-Graells R, Aguirre R, Sawaya MR, Arbing MA, Sherman T, Senarathne C, Yeates TO |
Structure (London, England : 1993) |
38513658 |
Structure |
2024 Jun 6 |
https://www.ncbi.nlm.nih.gov/pubmed/38513658 |
| Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens. |
Brown S, Antanasijevic A, Sewall LM, Garcia DM, Brouwer PJM, Sanders RW, Ward AB |
bioRxiv : the preprint server for biology |
38559180 |
bioRxiv |
2024 Mar 17 |
https://www.ncbi.nlm.nih.gov/pubmed/38559180 |
| Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin. |
Tonggu L, Wisedchaisri G, Gamal El-Din TM, Lenaeus MJ, Logan MM, Toma T, Du Bois J, Zheng N, Catterall WA |
Nature communications |
38485923 |
Nat Commun |
2024 Mar 14 |
https://www.ncbi.nlm.nih.gov/pubmed/38485923 |
| VitroJet: new features and case studies. |
Henderikx RJM, Mann D, Domanska A, Dong J, Shahzad S, Lak B, Filopoulou A, Ludig D, Grininger M, Momoh J, Laanto E, Oksanen HM, Bisikalo K, Williams PA, Butcher SJ, Peters PJ, Beulen BWAMM |
Acta crystallographica. Section D, Structural biology |
38488730 |
Acta Crystallogr D Struct Biol |
2024 Apr 1 |
https://www.ncbi.nlm.nih.gov/pubmed/38488730 |
| Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel. |
Karuppan S, Schrag LG, Pastrano CM, Jara-Oseguera A, Zubcevic L |
Proceedings of the National Academy of Sciences of the United States of America |
38923985 |
Proc Natl Acad Sci U S A |
2024 Jul 2 |
https://www.ncbi.nlm.nih.gov/pubmed/38923985 |
| Structural bases for Na(+)-Cl(-) cotransporter inhibition by thiazide diuretic drugs and activation by kinases. |
Zhao Y, Schubert H, Blakely A, Forbush B, Smith MD, Rinehart J, Cao E |
Nature communications |
39143061 |
Nat Commun |
2024 Aug 14 |
https://www.ncbi.nlm.nih.gov/pubmed/39143061 |
| Structural basis for inhibition of coagulation factor VIII reveals a shared antigenic hotspot on the C1 domain. |
Childers KC, Cowper B, Vaughan JD, McGill JR, Davulcu O, Lollar P, Doering CB, Coxon CH, Spiegel PC Jr |
Journal of thrombosis and haemostasis : JTH |
38849084 |
J Thromb Haemost |
2024 Sep |
https://www.ncbi.nlm.nih.gov/pubmed/38849084 |
| Molecular basis of the urate transporter URAT1 inhibition by gout drugs. |
Suo Y, Fedor JG, Zhang H, Tsolova K, Shi X, Sharma K, Kumari S, Borgnia M, Zhan P, Im W, Lee SY |
bioRxiv : the preprint server for biology |
39314352 |
bioRxiv |
2024 Sep 12 |
https://www.ncbi.nlm.nih.gov/pubmed/39314352 |
| P2X(7) receptors exhibit at least three modes of allosteric antagonism. |
Oken AC, Ditter IA, Lisi NE, Krishnamurthy I, Godsey MH, Mansoor SE |
Science advances |
39365862 |
Sci Adv |
2024 Oct 4 |
https://www.ncbi.nlm.nih.gov/pubmed/39365862 |
| Streptococcus pneumoniae GAPN is a key metabolic player necessary for host infection. |
Lee E, Saviola A, Bevers S, Redzic JS, Maroney SP, Shaw S, Tamkin E, Fulte S, Nemkov T, Meyer N, D'Alessandro A, Hansen KC, Clark SE, Eisenmesser E |
Protein science : a publication of the Protein Society |
39660954 |
Protein Sci |
2025 Jan |
https://www.ncbi.nlm.nih.gov/pubmed/39660954 |
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Proc Natl Acad Sci U S A |
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Epigenomes |
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2024 Jul 12 |
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Nature |
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Nature structural & molecular biology |
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2020 Nov 25 |
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| The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states. |
Santosh V, Musayev FN, Jaiswal R, Zárate-Pérez F, Vandewinkel B, Dierckx C, Endicott M, Sharifi K, Dryden K, Henckaerts E, Escalante CR |
Nucleic acids research |
33270897 |
Nucleic Acids Res |
2020 Dec 16 |
https://www.ncbi.nlm.nih.gov/pubmed/33270897 |
| A Robust Single-Particle Cryo-Electron Microscopy (cryo-EM) Processing Workflow with cryoSPARC, RELION, and Scipion. |
DiIorio MC, Kulczyk AW |
Journal of visualized experiments : JoVE |
35104261 |
J Vis Exp |
2022 Jan 31 |
https://www.ncbi.nlm.nih.gov/pubmed/35104261 |
| Active conformation of the p97-p47 unfoldase complex. |
Xu Y, Han H, Cooney I, Guo Y, Moran NG, Zuniga NR, Price JC, Hill CP, Shen PS |
Nature communications |
35552390 |
Nat Commun |
2022 May 12 |
https://www.ncbi.nlm.nih.gov/pubmed/35552390 |
| Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis. |
Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski P, Chhapra F, Saelices L |
bioRxiv : the preprint server for biology |
38496656 |
bioRxiv |
2024 Mar 9 |
https://www.ncbi.nlm.nih.gov/pubmed/38496656 |
| Amyloid fibril polymorphism in the heart of an ATTR amyloidosis patient with polyneuropathy attributed to the V122Δ variant. |
Ahmed Y, Nguyen BA, Afrin S, Singh V, Evers B, Singh P, Pedretti R, Wang L, Bassett P, Del Carmen Fernandez-Ramirez M, Pekala M, Kluve-Beckerman B, Saelices L |
bioRxiv : the preprint server for biology |
38766262 |
bioRxiv |
2024 May 10 |
https://www.ncbi.nlm.nih.gov/pubmed/38766262 |
| Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. |
Jiou J, Shaffer JM, Bernades NE, Fung HYJ, Kikumoto Dias J, D'Arcy S, Chook YM |
Proceedings of the National Academy of Sciences of the United States of America |
37450495 |
Proc Natl Acad Sci U S A |
2023 Jul 18 |
https://www.ncbi.nlm.nih.gov/pubmed/37450495 |
| Structural interplay of anesthetics and paralytics on muscle nicotinic receptors. |
Goswami U, Rahman MM, Teng J, Hibbs RE |
Nature communications |
37264005 |
Nat Commun |
2023 Jun 1 |
https://www.ncbi.nlm.nih.gov/pubmed/37264005 |
| Virion glycosylation influences mycobacteriophage immune recognition. |
Freeman KG, Robotham AC, Parks OB, Abad L, Jacobs-Sera D, Lauer MJ, Podgorski JM, Zhang Y, Williams JV, White SJ, Kelly JF, Hatfull GF, Pope WH |
Cell host & microbe |
37329881 |
Cell Host Microbe |
2023 Jul 12 |
https://www.ncbi.nlm.nih.gov/pubmed/37329881 |
| Structural Determination of Glucosyltransferase C by Cryo-Electron Microscopy. |
Xie Q, Cao J, Zhang H, Wu H |
Methods in molecular biology (Clifton, N.J.) |
37815721 |
Methods Mol Biol |
2024 |
https://www.ncbi.nlm.nih.gov/pubmed/37815721 |
| Activation of human STING by a molecular glue-like compound. |
Li J, Canham SM, Wu H, Henault M, Chen L, Liu G, Chen Y, Yu G, Miller HR, Hornak V, Brittain SM, Michaud GA, Tutter A, Broom W, Digan ME, McWhirter SM, Sivick KE, Pham HT, Chen CH, Tria GS, McKenna JM, Schirle M, Mao X, Nicholson TB, Wang Y, Jenkins JL, Jain RK, Tallarico JA, Patel SJ, Zheng L, Ross NT, Cho CY, Zhang X, Bai XC, Feng Y |
Nature chemical biology |
37828400 |
Nat Chem Biol |
2024 Mar |
https://www.ncbi.nlm.nih.gov/pubmed/37828400 |
| A strategic approach for efficient cryo-EM grid optimization using design of experiments. |
Haynes RM, Myers J, López CS, Evans J, Davulcu O, Yoshioka C |
Journal of structural biology |
38364988 |
J Struct Biol |
2025 Mar |
https://www.ncbi.nlm.nih.gov/pubmed/38364988 |
| Structural basis for Retriever-SNX17 assembly and endosomal sorting. |
Singla A, Boesch DJ, Joyce Fung HY, Ngoka C, Enriquez AS, Song R, Kramer DA, Han Y, Juneja P, Billadeau DD, Bai X, Chen Z, Turer EE, Burstein E, Chen B |
bioRxiv : the preprint server for biology |
38559023 |
bioRxiv |
2024 Mar 13 |
https://www.ncbi.nlm.nih.gov/pubmed/38559023 |
| A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases. |
Redzic JS, Rahkola J, Tran N, Holyoak T, Lee E, Martín-Galiano AJ, Meyer N, Zheng H, Eisenmesser E |
Communications biology |
36336763 |
Commun Biol |
2022 Nov 7 |
https://www.ncbi.nlm.nih.gov/pubmed/36336763 |
| Structural basis for APE1 processing DNA damage in the nucleosome. |
Weaver TM, Hoitsma NM, Spencer JJ, Gakhar L, Schnicker NJ, Freudenthal BD |
Nature communications |
36104361 |
Nat Commun |
2022 Sep 14 |
https://www.ncbi.nlm.nih.gov/pubmed/36104361 |
| 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. |
Srinivas P, Nosrati M, Zelinskaya N, Dey D, Comstock LR, Dunham CM, Conn GL |
bioRxiv : the preprint server for biology |
36993224 |
bioRxiv |
2023 Apr 30 |
https://www.ncbi.nlm.nih.gov/pubmed/36993224 |
| Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. |
Nadezhdin KD, Correia L, Shalygin A, Aktolun M, Neuberger A, Gudermann T, Kurnikova MG, Chubanov V, Sobolevsky AI |
Cell reports |
38615321 |
Cell Rep |
2024 Apr 23 |
https://www.ncbi.nlm.nih.gov/pubmed/38615321 |
| The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. |
Cruz VE, Weirich CS, Peddada N, Erzberger JP |
Nature communications |
38632236 |
Nat Commun |
2024 Apr 17 |
https://www.ncbi.nlm.nih.gov/pubmed/38632236 |
| An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. |
Morgan CE, Zhang Z, Bonomo RA, Yu EW |
mBio |
35100868 |
mBio |
2021 Feb 22 |
https://www.ncbi.nlm.nih.gov/pubmed/35100868 |
| Cryo-EM reveals a phosphorylated R-domain envelops the NBD1 catalytic domain in an ABC transporter. |
Souza Amado de Carvalho R, Rasel MSI, Khandelwal NK, Tomasiak TM |
Life science alliance |
39209537 |
Life Sci Alliance |
2024 Nov |
https://www.ncbi.nlm.nih.gov/pubmed/39209537 |
| The structure of full-length AFPK supports the ACP linker in a role that regulates iterative polyketide and fatty acid assembly. |
Schubert HL, Li F, Hill CP, Schmidt EW |
Proceedings of the National Academy of Sciences of the United States of America |
39913209 |
Proc Natl Acad Sci U S A |
2025 Feb 11 |
https://www.ncbi.nlm.nih.gov/pubmed/39913209 |
| Structural and functional dynamics of human cone cGMP-phosphodiesterase important for photopic vision. |
Singh S, Srivastava D, Boyd K, Artemyev NO |
Proceedings of the National Academy of Sciences of the United States of America |
39739818 |
Proc Natl Acad Sci U S A |
2025 Jan 7 |
https://www.ncbi.nlm.nih.gov/pubmed/39739818 |
| Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy. |
Schnicker NJ, Xu Z, Amir M, Gakhar L, Huang CL |
Scientific reports |
39747283 |
Sci Rep |
2025 Jan 2 |
https://www.ncbi.nlm.nih.gov/pubmed/39747283 |
| Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization. |
Lanning S, Aguilar-Hernández N, Serrão VHB, López T, O'Rourke SM, Lentz A, Ricemeyer L, Espinosa R, López S, Arias CF, DuBois RM |
Journal of virology |
39846739 |
J Virol |
2025 Feb 25 |
https://www.ncbi.nlm.nih.gov/pubmed/39846739 |
| Cryo-EM structure of the human Sirtuin 6-nucleosome complex. |
Chio US, Rechiche O, Bryll AR, Zhu J, Leith EM, Feldman JL, Peterson CL, Tan S, Armache JP |
Science advances |
37058572 |
Sci Adv |
2023 Apr 14 |
https://www.ncbi.nlm.nih.gov/pubmed/37058572 |
| Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2. |
Hu W, Song A, Zheng H |
Nature communications |
38684689 |
Nat Commun |
2024 Apr 29 |
https://www.ncbi.nlm.nih.gov/pubmed/38684689 |
| ATTRv-V30M amyloid fibrils from heart and nerves exhibit structural homogeneity. |
Nguyen BA, Afrin S, Yakubovska A, Singh V, Pedretti R, Bassett P, Pekala M, Alicea JV, Kunach P, Wang L, Lemoff A, Kluve-Beckerman B, Saelices L |
Structure (London, England : 1993) |
39423808 |
Structure |
2024 Dec 5 |
https://www.ncbi.nlm.nih.gov/pubmed/39423808 |
| Structure of human TRPV4 in complex with GTPase RhoA. |
Nadezhdin KD, Talyzina IA, Parthasarathy A, Neuberger A, Zhang DX, Sobolevsky AI |
Nature communications |
37353478 |
Nat Commun |
2023 Jun 23 |
https://www.ncbi.nlm.nih.gov/pubmed/37353478 |
| Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. |
Li M, Oliveira Passos D, Shan Z, Smith SJ, Sun Q, Biswas A, Choudhuri I, Strutzenberg TS, Haldane A, Deng N, Li Z, Zhao XZ, Briganti L, Kvaratskhelia M, Burke TR Jr, Levy RM, Hughes SH, Craigie R, Lyumkis D |
Science advances |
37478179 |
Sci Adv |
2023 Jul 21 |
https://www.ncbi.nlm.nih.gov/pubmed/37478179 |
| Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. |
Padi SKR, Vos MR, Godek RJ, Fuller JR, Kruse T, Hein JB, Nilsson J, Kelker MS, Page R, Peti W |
bioRxiv : the preprint server for biology |
37693408 |
bioRxiv |
2023 Aug 31 |
https://www.ncbi.nlm.nih.gov/pubmed/37693408 |
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Hu Q, Zhao D, Cui G, Bhandari J, Thompson JR, Botuyan MV, Mer G |
Molecular cell |
38242129 |
Mol Cell |
2024 Mar 7 |
https://www.ncbi.nlm.nih.gov/pubmed/38242129 |
| Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. |
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pękała M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L |
Nature communications |
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Nat Commun |
2024 Jan 17 |
https://www.ncbi.nlm.nih.gov/pubmed/38233397 |
| Kainate receptor channel opening and gating mechanism. |
Gangwar SP, Yelshanskaya MV, Nadezhdin KD, Yen LY, Newton TP, Aktolun M, Kurnikova MG, Sobolevsky AI |
Nature |
38778115 |
Nature |
2024 Jun |
https://www.ncbi.nlm.nih.gov/pubmed/38778115 |
| Structural insights into GABA(A) receptor potentiation by Quaalude. |
Chojnacka W, Teng J, Kim JJ, Jensen AA, Hibbs RE |
Nature communications |
38898000 |
Nat Commun |
2024 Jun 19 |
https://www.ncbi.nlm.nih.gov/pubmed/38898000 |
| High-resolution reconstruction of a C. elegans ribosome sheds light on evolutionary dynamics and tissue specificity. |
Sehgal E, Wohlenberg C, Soukup EM, Viscardi MJ, Serrão VHB, Arribere JA |
RNA (New York, N.Y.) |
39209556 |
RNA |
2024 Oct 16 |
https://www.ncbi.nlm.nih.gov/pubmed/39209556 |
| Metallic support films reduce optical heating in cryogenic correlative light and electron tomography. |
Dahlberg PD, Perez D, Hecksel CW, Chiu W, Moerner WE |
Journal of structural biology |
36191745 |
J Struct Biol |
2022 Dec |
https://www.ncbi.nlm.nih.gov/pubmed/36191745 |
| Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. |
Doran MH, Rynkiewicz MJ, Pavadai E, Bodt SML, Rasicci D, Moore JR, Yengo CM, Bullitt E, Lehman W |
The Journal of general physiology |
36459134 |
J Gen Physiol |
2023 Feb 6 |
https://www.ncbi.nlm.nih.gov/pubmed/36459134 |
| Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy. |
Logan GJ, Mietzsch M, Khandekar N, D'Silva A, Anderson D, Mandwie M, Hsi J, Nelson AR, Chipman P, Jackson J, Schofield P, Christ D, Goodnow CC, Reed JH, Farrar MA, McKenna R, Alexander IE |
Molecular therapy : the journal of the American Society of Gene Therapy |
37012705 |
Mol Ther |
2023 Jul 5 |
https://www.ncbi.nlm.nih.gov/pubmed/37012705 |
| Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. |
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS |
Nature communications |
37185252 |
Nat Commun |
2023 Apr 25 |
https://www.ncbi.nlm.nih.gov/pubmed/37185252 |
| Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution. |
Su Z, Zhang K, Kappel K, Li S, Palo MZ, Pintilie GD, Rangan R, Luo B, Wei Y, Das R, Chiu W |
Nature |
34381213 |
Nature |
2021 Aug |
https://www.ncbi.nlm.nih.gov/pubmed/34381213 |
| GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. |
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter J, Dror RO, Evers AS, Mukhopadhyay S, Manglik A |
bioRxiv : the preprint server for biology |
37292845 |
bioRxiv |
2023 May 24 |
https://www.ncbi.nlm.nih.gov/pubmed/37292845 |
| CryoEM structures of the human CLC-2 voltage gated chloride channel reveal a ball and chain gating mechanism. |
Xu M, Neelands T, Powers AS, Liu Y, Miller SD, Pintilie G, Bois JD, Dror RO, Chiu W, Maduke M |
bioRxiv : the preprint server for biology |
37645939 |
bioRxiv |
2023 Nov 29 |
https://www.ncbi.nlm.nih.gov/pubmed/37645939 |
| Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. |
Yu Z, Chen J, Takagi E, Wang F, Saha B, Liu X, Joubert LM, Gleason CE, Jin M, Li C, Nowotny C, Agard D, Cheng Y, Pearce D |
The Journal of biological chemistry |
35926713 |
J Biol Chem |
2022 Sep |
https://www.ncbi.nlm.nih.gov/pubmed/35926713 |
| Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. |
Fan M, Zhang J, Lee CL, Zhang J, Feng L |
Nature |
36792826 |
Nature |
2023 Feb |
https://www.ncbi.nlm.nih.gov/pubmed/36792826 |
| Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. |
Doran MH, Rynkiewicz MJ, Rasicci D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W |
The Journal of general physiology |
36633586 |
J Gen Physiol |
2023 Mar 6 |
https://www.ncbi.nlm.nih.gov/pubmed/36633586 |
| Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. |
Doran MH, Pavadai E, Rynkiewicz MJ, Walklate J, Bullitt E, Moore JR, Regnier M, Geeves MA, Lehman W |
Biophysical journal |
32730789 |
Biophys J |
2020 Aug 18 |
https://www.ncbi.nlm.nih.gov/pubmed/32730789 |
| Structure and mechanism of the alkane-oxidizing enzyme AlkB. |
Guo X, Zhang J, Han L, Lee J, Williams SC, Forsberg A, Xu Y, Austin RN, Feng L |
Nature communications |
37069165 |
Nat Commun |
2023 Apr 17 |
https://www.ncbi.nlm.nih.gov/pubmed/37069165 |
| Autoantibody mimicry of hormone action at the thyrotropin receptor. |
Faust B, Billesbølle CB, Suomivuori CM, Singh I, Zhang K, Hoppe N, Pinto AFM, Diedrich JK, Muftuoglu Y, Szkudlinski MW, Saghatelian A, Dror RO, Cheng Y, Manglik A |
Nature |
35940205 |
Nature |
2022 Sep |
https://www.ncbi.nlm.nih.gov/pubmed/35940205 |
| Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation. |
Abskharon R, Sawaya MR, Boyer DR, Cao Q, Nguyen BA, Cascio D, Eisenberg DS |
Proceedings of the National Academy of Sciences of the United States of America |
35377792 |
Proc Natl Acad Sci U S A |
2022 Apr 12 |
https://www.ncbi.nlm.nih.gov/pubmed/35377792 |
| Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. |
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS |
The Journal of experimental medicine |
35297953 |
J Exp Med |
2022 Apr 4 |
https://www.ncbi.nlm.nih.gov/pubmed/35297953 |
| Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. |
Kretsch RC, Xu L, Zheludev IN, Zhou X, Huang R, Nye G, Li S, Zhang K, Chiu W, Das R |
bioRxiv : the preprint server for biology |
38076883 |
bioRxiv |
2023 Nov 27 |
https://www.ncbi.nlm.nih.gov/pubmed/38076883 |
| Structural dynamics of GluK2 kainate receptors in apo and partial agonist bound states. |
Bogdanović N, Segura-Covarrubias G, Zhang L, Tajima N |
Research square |
38076992 |
Res Sq |
2023 Dec 2 |
https://www.ncbi.nlm.nih.gov/pubmed/38076992 |
| The Structures of Secretory IgA in complex with Streptococcus pyogenes M4 and human CD89 provide insights on mucosal host-pathogen interactions. |
Liu Q, Stadtmueller BM |
bioRxiv : the preprint server for biology |
37662389 |
bioRxiv |
2023 Aug 26 |
https://www.ncbi.nlm.nih.gov/pubmed/37662389 |
| Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. |
Rosenberg GM, Abskharon R, Boyer DR, Ge P, Sawaya MR, Eisenberg DS |
PNAS nexus |
38077690 |
PNAS Nexus |
2023 Dec |
https://www.ncbi.nlm.nih.gov/pubmed/38077690 |
| Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor. |
Lokareddy RK, Hou CD, Forti F, Iglesias SM, Li F, Pavlenok M, Horner DS, Niederweis M, Briani F, Cingolani G |
Nature communications |
39353939 |
Nat Commun |
2024 Oct 1 |
https://www.ncbi.nlm.nih.gov/pubmed/39353939 |
| Molecular basis of proton-sensing by G protein-coupled receptors. |
Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrota E, Grimes PR, Zahm A, Trinidad DD, English J, Coyote-Maestas W, Manglik A |
bioRxiv : the preprint server for biology |
38659943 |
bioRxiv |
2024 Apr 18 |
https://www.ncbi.nlm.nih.gov/pubmed/38659943 |
| Scaffold-enabled high-resolution cryo-EM structure determination of RNA. |
Haack DB, Rudolfs B, Jin S, Khitun A, Weeks KM, Toor N |
Nature communications |
39837824 |
Nat Commun |
2025 Jan 21 |
https://www.ncbi.nlm.nih.gov/pubmed/39837824 |
| Structures of telomerase at several steps of telomere repeat synthesis. |
He Y, Wang Y, Liu B, Helmling C, Sušac L, Cheng R, Zhou ZH, Feigon J |
Nature |
33981033 |
Nature |
2021 May |
https://www.ncbi.nlm.nih.gov/pubmed/33981033 |
| Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. |
Zhang K, Zheludev IN, Hagey RJ, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Wu MT, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, D'Souza V, Glenn JS, Chiu W, Das R |
Nature structural & molecular biology |
34426697 |
Nat Struct Mol Biol |
2021 Sep |
https://www.ncbi.nlm.nih.gov/pubmed/34426697 |
| Electron crystallography of chiral and non-chiral small molecules. |
Zhou W, Bammes B, Mitchell PG, Betz K, Chiu W |
Ultramicroscopy |
34695647 |
Ultramicroscopy |
2022 Jan |
https://www.ncbi.nlm.nih.gov/pubmed/34695647 |
| Structures of the nitrogenase complex prepared under catalytic turnover conditions. |
Rutledge HL, Cook BD, Nguyen HPM, Herzik MA Jr, Tezcan FA |
Science (New York, N.Y.) |
35901182 |
Science |
2022 Aug 19 |
https://www.ncbi.nlm.nih.gov/pubmed/35901182 |
| Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold. |
Fontana P, Dong Y, Pi X, Tong AB, Hecksel CW, Wang L, Fu TM, Bustamante C, Wu H |
Science (New York, N.Y.) |
35679401 |
Science |
2022 Jun 10 |
https://www.ncbi.nlm.nih.gov/pubmed/35679401 |
| Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. |
Yang R, Ko YH, Li F, Lokareddy RK, Hou CD, Kim C, Klein S, Antolínez S, Marín JF, Pérez-Segura C, Jarrold MF, Zlotnick A, Hadden-Perilla JA, Cingolani G |
Science advances |
38198557 |
Sci Adv |
2024 Jan 12 |
https://www.ncbi.nlm.nih.gov/pubmed/38198557 |
| Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F(1)-F(o) coupling. |
Sharma S, Luo M, Patel H, Mueller DM, Liao M |
Nature structural & molecular biology |
38316880 |
Nat Struct Mol Biol |
2024 Apr |
https://www.ncbi.nlm.nih.gov/pubmed/38316880 |
| GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. |
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter JF, Dror RO, Evers AS, Mukhopadhyay S, Manglik A |
Nature structural & molecular biology |
38326651 |
Nat Struct Mol Biol |
2024 Apr |
https://www.ncbi.nlm.nih.gov/pubmed/38326651 |
| Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus. |
Velez M, Mietzsch M, Hsi J, Bell L, Chipman P, Fu X, McKenna R |
Viruses |
37766206 |
Viruses |
2023 Aug 24 |
https://www.ncbi.nlm.nih.gov/pubmed/37766206 |
| Cryo-EM Structure of a Human LECT2 Amyloid Fibril Reveals a Network of Polar Ladders at its Core. |
Richards LS, Flores MD, Zink S, Schibrowsky NA, Sawaya MR, Rodriguez JA |
bioRxiv : the preprint server for biology |
36798409 |
bioRxiv |
2023 Feb 11 |
https://www.ncbi.nlm.nih.gov/pubmed/36798409 |
| A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. |
Weidenbacher PA, Sanyal M, Friedland N, Tang S, Arunachalam PS, Hu M, Kumru OS, Morris MK, Fontenot J, Shirreff L, Do J, Cheng YC, Vasudevan G, Feinberg MB, Villinger FJ, Hanson C, Joshi SB, Volkin DB, Pulendran B, Kim PS |
bioRxiv : the preprint server for biology |
36597527 |
bioRxiv |
2022 Dec 26 |
https://www.ncbi.nlm.nih.gov/pubmed/36597527 |
| A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. |
Weidenbacher PA, Sanyal M, Friedland N, Tang S, Arunachalam PS, Hu M, Kumru OS, Morris MK, Fontenot J, Shirreff L, Do J, Cheng YC, Vasudevan G, Feinberg MB, Villinger FJ, Hanson C, Joshi SB, Volkin DB, Pulendran B, Kim PS |
Nature communications |
37069151 |
Nat Commun |
2023 Apr 17 |
https://www.ncbi.nlm.nih.gov/pubmed/37069151 |
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Nature communications |
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Nat Commun |
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bioRxiv |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Nat Chem Biol |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Nature microbiology |
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Nature structural & molecular biology |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Science advances |
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Sci Adv |
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Nat Chem Biol |
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Molecular cell |
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Mol Cell |
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Nature structural & molecular biology |
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bioRxiv : the preprint server for biology |
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bioRxiv : the preprint server for biology |
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Proc Natl Acad Sci U S A |
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bioRxiv |
2023 Mar 15 |
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Proc Natl Acad Sci U S A |
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Scientific reports |
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Sci Rep |
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Nature |
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Nature |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2021 Jul 9 |
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Molecular cell |
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Mol Cell |
2022 Jun 2 |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Nature |
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Nature |
2024 Feb |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 May 13 |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
2023 Nov |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2023 Sep 26 |
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2023 Dec 7 |
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International journal of molecular sciences |
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Int J Mol Sci |
2024 Oct 21 |
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Cell |
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2024 Dec 12 |
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2024 Jun |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Aug 5 |
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Science advances |
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Sci Adv |
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Nature |
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Nature |
2024 Nov |
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bioRxiv : the preprint server for biology |
40161664 |
bioRxiv |
2025 Mar 10 |
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J Struct Biol X |
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Sci Immunol |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Nat Struct Mol Biol |
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Proc Natl Acad Sci U S A |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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33758867 |
bioRxiv |
2021 Mar 14 |
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Cell host & microbe |
33789084 |
Cell Host Microbe |
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Cell |
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Proc Natl Acad Sci U S A |
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Cell |
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Cell |
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Nature communications |
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Nat Commun |
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Structure |
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Proc Natl Acad Sci U S A |
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Nature communications |
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Nat Commun |
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Cell Rep |
2021 Jan 12 |
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Journal of structural biology |
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J Struct Biol |
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Trends in biochemical sciences |
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Trends Biochem Sci |
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Communications biology |
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Commun Biol |
2022 Oct 3 |
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Frontiers in immunology |
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Front Immunol |
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Curr Opin Struct Biol |
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Nature |
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Nature |
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The Journal of biological chemistry |
36528064 |
J Biol Chem |
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Structure |
2024 May 2 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Research square |
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Cell |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Nov 20 |
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bioRxiv |
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Cell reports |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2021 Mar 23 |
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International journal of molecular sciences |
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Int J Mol Sci |
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Science (New York, N.Y.) |
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Science |
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Nanoscale advances |
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Nanoscale Adv |
2023 Oct 24 |
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Nature communications |
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Nat Commun |
2023 Jul 20 |
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Hu Z, Zheng X, Yang J |
Nature communications |
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Nat Commun |
2023 Jul 18 |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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J Biol Chem |
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Frontiers in molecular biosciences |
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Front Mol Biosci |
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PLoS biology |
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PLoS Biol |
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Acta Crystallogr F Struct Biol Commun |
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Nature communications |
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Nat Commun |
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Nature |
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Acta Crystallogr C Struct Chem |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Nov 5 |
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Acta crystallographica. Section F, Structural biology communications |
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Acta Crystallogr F Struct Biol Commun |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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bioRxiv |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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40067903 |
Proc Natl Acad Sci U S A |
2025 Mar 18 |
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Nature structural & molecular biology |
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Nature structural & molecular biology |
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Acta crystallographica. Section C, Structural chemistry |
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Acta Crystallogr C Struct Chem |
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Nature structural & molecular biology |
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Molecular cell |
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Nature |
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Nature communications |
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Acta crystallographica. Section F, Structural biology communications |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Proceedings of the ACM on computer graphics and interactive techniques |
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Proc ACM Comput Graph Interact Tech |
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Acta crystallographica. Section D, Structural biology |
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Acta Crystallogr D Struct Biol |
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IEEE transactions on circuits and systems for video technology : a publication of the Circuits and Systems Society |
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IEEE Trans Circuits Syst Video Technol |
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International journal of human-computer interaction |
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Annu Rev Biomed Data Sci |
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STAR protocols |
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STAR Protoc |
2024 Jun 21 |
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36789166 |
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2023 Jan 20 |
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