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Program Publications

Title Authors Journal PubMedID Publication Date
Absolute structure determination of Berkecoumarin by X-ray and electron diffraction. Decato, Daniel; Palatinus, Lukáš; Stierle, Andrea; Stierle, Donald Acta crystallographica. Section C, Structural chemistry 38598330 2024 May 01
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. Held, Richard G; Liang, Jiahao; Brunger, Axel T Proceedings of the National Academy of Sciences of the United States of America 38923992 2024 Jul 02
Structural mechanisms for VMAT2 inhibition by tetrabenazine. Dalton, Michael P; Cheng, Mary Hongying; Bahar, Ivet; Coleman, Jonathan A bioRxiv : the preprint server for biology 37732203 2024 Feb 01
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Hoppe, Nicholas; Harrison, Simone; Hwang, Sun-Hee; Chen, Ziwei; Karelina, Masha; Deshpande, Ishan; Suomivuori, Carl-Mikael; Palicharla, Vivek R; Berry, Samuel P; Tschaikner, Philipp; Regele, Dominik; Covey, Douglas F; Stefan, Eduard; Marks, Debora S; Reiter, Jeremy F; Dror, Ron O; Evers, Alex S; Mukhopadhyay, Saikat; Manglik, Aashish Nature structural & molecular biology 38326651 2024 Apr
CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization. Serbynovskyi, Viacheslav; Wang, Jing; Chua, Eugene Yd; Ishemgulova, Aygul; Alink, Lambertus M; Budell, William C; Johnston, Jake D; Dubbeldam, Charlie; Gonzalez, Fabio A; Rozovsky, Sharon; Eng, Edward T; de Marco, Alex; Noble, Alex J bioRxiv : the preprint server for biology 38328036 2024 May 13
Miffi: Improving the accuracy of CNN-based cryo-EM micrograph filtering with fine-tuning and Fourier space information. Xu, Da; Ando, Nozomi bioRxiv : the preprint server for biology 38405773 2024 Feb 27
Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Kretsch, Rachael C; Xu, Lily; Zheludev, Ivan N; Zhou, Xueting; Huang, Rui; Nye, Grace; Li, Shanshan; Zhang, Kaiming; Chiu, Wah; Das, Rhiju Proceedings of the National Academy of Sciences of the United States of America 38427602 2024 Mar 05
Mobile barrier mechanisms for Na+-coupled symport in an MFS sugar transporter. Hariharan, Parameswaran; Shi, Yuqi; Katsube, Satoshi; Willibal, Katleen; Burrows, Nathan D; Mitchell, Patrick; Bakhtiiari, Amirhossein; Stanfield, Samantha; Pardon, Els; Kaback, H Ronald; Liang, Ruibin; Steyaert, Jan; Viner, Rosa; Guan, Lan eLife 38381130 2024 Feb 21
Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation. Burke, Sean M; Avstrikova, Mariia; Noviello, Colleen M; Mukhtasimova, Nuriya; Changeux, Jean-Pierre; Thakur, Ganesh A; Sine, Steven M; Cecchini, Marco; Hibbs, Ryan E Cell 38382524 2024 Feb 29
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nguyen, Binh An; Singh, Virender; Afrin, Shumaila; Yakubovska, Anna; Wang, Lanie; Ahmed, Yasmin; Pedretti, Rose; Fernandez-Ramirez, Maria Del Carmen; Singh, Preeti; Pękała, Maja; Cabrera Hernandez, Luis O; Kumar, Siddharth; Lemoff, Andrew; Gonzalez-Prieto, Roman; Sawaya, Michael R; Eisenberg, David S; Benson, Merrill Douglas; Saelices, Lorena Nature communications 38233397 2024 Jan 17
Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor. Mazzaferro, Simone; Kang, Guipeun; Natarajan, Kathiresan; Hibbs, Ryan E; Sine, Steven M British journal of pharmacology 38454578 2024 Jul
Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Hu, Qi; Zhao, Debiao; Cui, Gaofeng; Bhandari, Janarjan; Thompson, James R; Botuyan, Maria Victoria; Mer, Georges Molecular cell 38242129 2024 Mar 07
Structures of the essential efflux pump EfpA from Mycobacterium tuberculosis reveal the mechanisms of substrate transport and small-molecule inhibition. Wang, Shuhui; Wang, Kun; Song, Kangkang; Li, Pengfei; Li, Dongying; Sun, Yajie; Mei, Ye; Xu, Chen; Liao, Maofu Research square 38260587 2024 Jan 05
Cryo-EM Structure of AAV2 Rep68 bound to integration site AAVS1: Insights into the mechanism of DNA melting. Jaiswal, R; Santosh, V; Braud, B; Washington, A; Escalante, Carlos R bioRxiv : the preprint server for biology 38617369 2024 Apr 02
Structural mechanisms for VMAT2 inhibition by tetrabenazine. Dalton, Michael P; Cheng, Mary Hongying; Bahar, Ivet; Coleman, Jonathan A eLife 38517752 2024 Mar 22
Dramatic Changes in Mitochondrial Subcellular Location and Morphology Accompany Activation of the CO2 Concentrating Mechanism. Findinier, Justin; Joubert, Lydia-Marie; Schmid, Michael F; Malkovskiy, Andrey; Chiu, Wah; Burlacot, Adrien; Grossman, Arthur R bioRxiv : the preprint server for biology 38585955 2024 Mar 27
Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination. Clark, Jordan; Hoxie, Irene; Adelsberg, Daniel C; Sapse, Iden A; Andreata-Santos, Robert; Yong, Jeremy S; Amanat, Fatima; Tcheou, Johnstone; Raskin, Ariel; Singh, Gagandeep; González-Domínguez, Irene; Edgar, Julia E; Bournazos, Stylianos; Sun, Weina; Carreño, Juan Manuel; Simon, Viviana; Ellebedy, Ali H; Bajic, Goran; Krammer, Florian bioRxiv : the preprint server for biology 38464151 2024 Mar 01
Blueprinting extendable nanomaterials with standardized protein blocks. Huddy, Timothy F; Hsia, Yang; Kibler, Ryan D; Xu, Jinwei; Bethel, Neville; Nagarajan, Deepesh; Redler, Rachel; Leung, Philip J Y; Weidle, Connor; Courbet, Alexis; Yang, Erin C; Bera, Asim K; Coudray, Nicolas; Calise, S John; Davila-Hernandez, Fatima A; Han, Hannah L; Carr, Kenneth D; Li, Zhe; McHugh, Ryan; Reggiano, Gabriella; Kang, Alex; Sankaran, Banumathi; Dickinson, Miles S; Coventry, Brian; Brunette, T J; Liu, Yulai; Dauparas, Justas; Borst, Andrew J; Ekiert, Damian; Kollman, Justin M; Bhabha, Gira; Baker, David Nature 38480887 2024 Mar
Protocol to study CCT-mediated folding of Gβ5 by single-particle cryo-EM. Sass, Mikaila I; Wang, Shuxin; Mack, Deirdre; Cottam, Samuel L; Shen, Peter S; Willardson, Barry M STAR protocols 38848218 2024 Jun 21
Structural basis for inhibition of coagulation factor VIII reveals a shared antigenic hotspot on the C1 domain. Childers, Kenneth C; Cowper, Ben; Vaughan, Jordan D; McGill, Juliet R; Davulcu, Omar; Lollar, Pete; Doering, Christopher B; Coxon, Carmen H; Spiegel Jr, Paul C Journal of thrombosis and haemostasis : JTH 38849084 2024 Sep
Structural basis for Retriever-SNX17 assembly and endosomal sorting. Singla, Amika; Boesch, Daniel J; Joyce Fung, Ho Yee; Ngoka, Chigozie; Enriquez, Avery S; Song, Ran; Kramer, Daniel A; Han, Yan; Juneja, Puneet; Billadeau, Daniel D; Bai, Xiaochen; Chen, Zhe; Turer, Emre E; Burstein, Ezra; Chen, Baoyu bioRxiv : the preprint server for biology 38559023 2024 Mar 13
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. Edman, Natasha I; Phal, Ashish; Redler, Rachel L; Schlichthaerle, Thomas; Srivatsan, Sanjay R; Ehnes, Devon Duron; Etemadi, Ali; An, Seong J; Favor, Andrew; Li, Zhe; Praetorius, Florian; Gordon, Max; Vincent, Thomas; Marchiano, Silvia; Blakely, Leslie; Lin, Chuwei; Yang, Wei; Coventry, Brian; Hicks, Derrick R; Cao, Longxing; Bethel, Neville; Heine, Piper; Murray, Analisa; Gerben, Stacey; Carter, Lauren; Miranda, Marcos; Negahdari, Babak; Lee, Sangwon; Trapnell, Cole; Zheng, Ying; Murry, Charles E; Schweppe, Devin K; Freedman, Benjamin S; Stewart, Lance; Ekiert, Damian C; Schlessinger, Joseph; Shendure, Jay; Bhabha, Gira; Ruohola-Baker, Hannele; Baker, David Cell 38861993 2024 Jul 11
Multi-species cryoEM calibration and workflow verification standard. Bobe, Daija; Kopylov, Mykhailo; Miller, Jessalyn; Owji, Aaron P; Eng, Edward T bioRxiv : the preprint server for biology 39149318 2024 Aug 05
Preparing research samples for safe arrival at centers and facilities: recipes for successful experiments. Bowman, Sarah E J; Byrnes, James; Russi, Silvia; Zimanyi, Christina M Acta crystallographica. Section F, Structural biology communications 38990054 2024 Aug 01
CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization. Serbynovskyi, Viacheslav; Wang, Jing; Chua, Eugene Yd; Ishemgulova, Aygul; Alink, Lambertus M; Budell, William C; Johnston, Jake D; Dubbeldam, Charlie; Gonzalez, Fabio A; Rozovsky, Sharon; Eng, Edward T; de Marco, Alex; Noble, Alex J Research square 39011111 2024 Jul 02
High-affinity agonism at the P2X7 receptor is mediated by three residues outside the orthosteric pocket. Oken, Adam C; Lisi, Nicolas E; Krishnamurthy, Ipsita; McCarthy, Alanna E; Godsey, Michael H; Glasfeld, Arthur; Mansoor, Steven E Nature communications 39107314 2024 Aug 06
Structure of the human dopamine transporter and mechanisms of inhibition. Srivastava, Dushyant Kumar; Navratna, Vikas; Tosh, Dilip K; Chinn, Audrey; Sk, Md Fulbabu; Tajkhorshid, Emad; Jacobson, Kenneth A; Gouaux, Eric Nature 39112705 2024 Aug
C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. Consalvo, Claudia D; Aderounmu, Adedeji M; Donelick, Helen M; Aruscavage, P Joe; Eckert, Debra M; Shen, Peter S; Bass, Brenda L bioRxiv : the preprint server for biology 37790392 2024 Jan 24
Structural Determination of Glucosyltransferase C by Cryo-Electron Microscopy. Xie, Qing; Cao, Jianhao; Zhang, Hua; Wu, Hui Methods in molecular biology (Clifton, N.J.) 37815721 2024
Activation of human STING by a molecular glue-like compound. Li, Jie; Canham, Stephen M; Wu, Hua; Henault, Martin; Chen, Lihao; Liu, Guoxun; Chen, Yu; Yu, Gary; Miller, Howard R; Hornak, Viktor; Brittain, Scott M; Michaud, Gregory A; Tutter, Antonin; Broom, Wendy; Digan, Mary Ellen; McWhirter, Sarah M; Sivick, Kelsey E; Pham, Helen T; Chen, Christine H; Tria, George S; McKenna, Jeffery M; Schirle, Markus; Mao, Xiaohong; Nicholson, Thomas B; Wang, Yuan; Jenkins, Jeremy L; Jain, Rishi K; Tallarico, John A; Patel, Sejal J; Zheng, Lianxing; Ross, Nathan T; Cho, Charles Y; Zhang, Xuewu; Bai, Xiao-Chen; Feng, Yan Nature chemical biology 37828400 2024 Mar
Structural basis of Gabija anti-phage defence and viral immune evasion. Antine, Sadie P; Johnson, Alex G; Mooney, Sarah E; Leavitt, Azita; Mayer, Megan L; Yirmiya, Erez; Amitai, Gil; Sorek, Rotem; Kranzusch, Philip J Nature 37992757 2024 Jan
CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Xu, Mengyuan; Neelands, Torben; Powers, Alexander S; Liu, Yan; Miller, Steven D; Pintilie, Grigore D; Bois, J Du; Dror, Ron O; Chiu, Wah; Maduke, Merritt eLife 38345841 2024 Feb 12
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications. Cookis, Trinity; Lydecker, Alexandria; Sauer, Paul; Kasinath, Vignesh; Nogales, Eva bioRxiv : the preprint server for biology 38370759 2024 Feb 10
An in vitro experimental pipeline to characterize the epitope of a SARS-CoV-2 neutralizing antibody. Atanasoff, Kristina E; Brambilla, Luca; Adelsberg, Daniel C; Kowdle, Shreyas; Stevens, Christian S; Slamanig, Stefan; Hung, Chuan-Tien; Fu, Yanwen; Lim, Reyna; Tran, Linh; Allen, Robert; Sun, Weina; Duty, J Andrew; Bajic, Goran; Lee, Benhur; Tortorella, Domenico mBio 38054729 2024 Jan 16
Mechanism of anion exchange and small-molecule inhibition of pendrin. Wang, Lie; Hoang, Anthony; Gil-Iturbe, Eva; Laganowsky, Arthur; Quick, Matthias; Zhou, Ming Nature communications 38184688 2024 Jan 06
Miffi: Improving the accuracy of CNN-based cryo-EM micrograph filtering with fine-tuning and Fourier space information. Xu, Da; Ando, Nozomi Journal of structural biology 38431179 2024 Jun
Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Yang, Ruoyu; Ko, Ying-Hui; Li, Fenglin; Lokareddy, Ravi K; Hou, Chun-Feng David; Kim, Christine; Klein, Shelby; Antolínez, Santiago; Marín, Juan F; Pérez-Segura, Carolina; Jarrold, Martin F; Zlotnick, Adam; Hadden-Perilla, Jodi A; Cingolani, Gino Science advances 38198557 2024 Jan 12
Cryo-EM analysis of Pseudomonas phage Pa193 structural components. Cingolani, Gino; Iglesias, Stephano; Hou, Chun-Feng; Lemire, Sebastien; Soriaga, Angela; Kyme, Pierre Research square 38659960 2024 Apr 12
Applying 3D ED/MicroED workflows toward the next frontiers. Aragon, Mahira; Bowman, Sarah E J; Chen, Chun Hsing; de la Cruz, M Jason; Decato, Daniel A; Eng, Edward T; Flatt, Kristen M; Gulati, Sahil; Li, Yuchen; Lomba, Charles J; Mercado, Brandon; Miller, Jessalyn; Palatinus, Lukáš; Rice, William J; Waterman, David; Zimanyi, Christina M Acta crystallographica. Section C, Structural chemistry 38712546 2024 Jun 01
Structural transitions enable interleukin-18 maturation and signaling. Dong, Ying; Bonin, Jeffrey P; Devant, Pascal; Liang, Zhuoyi; Sever, Alexander I M; Mintseris, Julian; Aramini, James M; Du, Gang; Gygi, Stephen P; Kagan, Jonathan C; Kay, Lewis E; Wu, Hao Immunity 38733997 2024 Jul 09
Caenorhabditis elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. Consalvo, Claudia D; Aderounmu, Adedeji M; Donelick, Helen M; Aruscavage, P Joseph; Eckert, Debra M; Shen, Peter S; Bass, Brenda L eLife 38747717 2024 May 15
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. Eisenberg, David; Hou, Ke; Ge, Peng; Sawaya, Michael; Dolinsky, Joshua; Yang, Yuan; Jiang, Yi Xiao; Lutter, Liisa; Boyer, David; Cheng, Xinyi; Pi, Justin; Zhang, Jeffrey; Lu, Jiahui; Yang, Shixin; Yu, Zhiheng; Feigon, Juli Research square 38766197 2024 May 08
Amyloid fibril polymorphism in the heart of an ATTR amyloidosis patient with polyneuropathy attributed to the V122Δ variant. Ahmed, Yasmin; Nguyen, Binh An; Afrin, Shumaila; Singh, Virender; Evers, Bret; Singh, Preeti; Pedretti, Rose; Wang, Lanie; Bassett, Parker; Del Carmen Fernandez-Ramirez, Maria; Pekala, Maja; Kluve-Beckerman, Barbara; Saelices, Lorena bioRxiv : the preprint server for biology 38766262 2024 May 10
Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. Baier, Alexander S; Gioacchini, Nathan; Eek, Priit; Leith, Erik M; Tan, Song; Peterson, Craig L eLife 38809771 2024 May 29
Mechanisms of actin filament severing and elongation by formins. Palmer, Nicholas J; Barrie, Kyle R; Dominguez, Roberto Nature 38843827 2024 Aug
Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens. Brown, Sharidan; Antanasijevic, Aleksandar; Sewall, Leigh M; Garcia, Daniel Montiel; Brouwer, Philip J M; Sanders, Rogier W; Ward, Andrew B bioRxiv : the preprint server for biology 38559180 2024 Mar 17
Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Erramilli, Satchal K; Dominik, Pawel K; Ogbu, Chinemerem P; Kossiakoff, Anthony A; Vecchio, Alex J Communications biology 38886509 2024 Jun 17
Hub stability in the calcium calmodulin-dependent protein kinase II. Chien, Chih-Ta; Puhl, Henry; Vogel, Steven S; Molloy, Justin E; Chiu, Wah; Khan, Shahid Communications biology 38918547 2024 Jun 25
Structural and Biochemical Characterization of the Nucleosome Containing Variants H3.3 and H2A.Z. Jung, Harry; Sokolova, Vladyslava; Lee, Gahyun; Stevens, Victoria Rose; Tan, Dongyan Epigenomes 38920622 2024 May 27
Dynamic fibrillar assembly of αB-crystallin induced by perturbation of the conserved NT-IXI motif resolved by cryo-EM. McFarland, Russell; Reichow, Steve bioRxiv : the preprint server for biology 38585788 2024 Mar 27
Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor. Cingolani, Gino; Lokareddy, Ravi; Hou, Chun-Feng; Forti, Francesca; Iglesias, Stephano; Li, Fenglin; Pavlenok, Mikhail; Niederweis, Michael; Briani, Federica Research square 38463957 2024 Feb 21
Kainate receptor channel opening and gating mechanism. Gangwar, Shanti Pal; Yelshanskaya, Maria V; Nadezhdin, Kirill D; Yen, Laura Y; Newton, Thomas P; Aktolun, Muhammed; Kurnikova, Maria G; Sobolevsky, Alexander I Nature 38778115 2024 Jun
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis. Nguyen, Binh An; Singh, Virender; Afrin, Shumaila; Singh, Preeti; Pekala, Maja; Ahmed, Yasmin; Pedretti, Rose; Canepa, Jacob; Lemoff, Andrew; Kluve-Beckerman, Barbara; Wydorski, Pawel; Chhapra, Farzeen; Saelices, Lorena bioRxiv : the preprint server for biology 38496656 2024 Mar 09
A suite of designed protein cages using machine learning and protein fragment-based protocols. Meador, Kyle; Castells-Graells, Roger; Aguirre, Roman; Sawaya, Michael R; Arbing, Mark A; Sherman, Trent; Senarathne, Chethaka; Yeates, Todd O Structure (London, England : 1993) 38513658 2024 Jun 06
Cryo-EM sample preparation for high-resolution structure studies. Wang, Liguo; Zimanyi, Christina M Acta crystallographica. Section F, Structural biology communications 38530656 2024 Apr 01
Structures of the Mycobacterium tuberculosis efflux pump EfpA reveal the mechanisms of transport and inhibition. Wang, Shuhui; Wang, Kun; Song, Kangkang; Lai, Zon Weng; Li, Pengfei; Li, Dongying; Sun, Yajie; Mei, Ye; Xu, Chen; Liao, Maofu Nature communications 39231991 2024 Sep 04
Assembly of respiratory syncytial virus matrix protein lattice and its coordination with fusion glycoprotein trimers. Sibert, Bryan S; Kim, Joseph Y; Yang, Jie E; Ke, Zunlong; Stobart, Christopher C; Moore, Martin L; Wright, Elizabeth R Nature communications 39004634 2024 Jul 14
Structural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction. Chen, Xinyi; Guo, Yiran; Zhao, Ting; Lu, Jiuwei; Fang, Jian; Wang, Yinsheng; Wang, Gang Greg; Song, Jikui Nature communications 39043678 2024 Jul 23
Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore. Gao, Xiaolong; Yeh, Han-I; Yang, Zhengrong; Fan, Chen; Jiang, Fan; Howard, Rebecca J; Lindahl, Erik; Kappes, John C; Hwang, Tzyh-Chang Nature communications 39107303 2024 Aug 06
Structural bases for Na+-Cl- cotransporter inhibition by thiazide diuretic drugs and activation by kinases. Zhao, Yongxiang; Schubert, Heidi; Blakely, Alan; Forbush, Biff; Smith, Micholas Dean; Rinehart, Jesse; Cao, Erhu Nature communications 39143061 2024 Aug 14
Structures, functions and adaptations of the human LINE-1 ORF2 protein. Baldwin, Eric T; van Eeuwen, Trevor; Hoyos, David; Zalevsky, Arthur; Tchesnokov, Egor P; Sánchez, Roberto; Miller, Bryant D; Di Stefano, Luciano H; Ruiz, Francesc Xavier; Hancock, Matthew; Işik, Esin; Mendez-Dorantes, Carlos; Walpole, Thomas; Nichols, Charles; Wan, Paul; Riento, Kirsi; Halls-Kass, Rowan; Augustin, Martin; Lammens, Alfred; Jestel, Anja; Upla, Paula; Xibinaku, Kera; Congreve, Samantha; Hennink, Maximiliaan; Rogala, Kacper B; Schneider, Anna M; Fairman, Jennifer E; Christensen, Shawn M; Desrosiers, Brian; Bisacchi, Gregory S; Saunders, Oliver L; Hafeez, Nafeeza; Miao, Wenyan; Kapeller, Rosana; Zaller, Dennis M; Sali, Andrej; Weichenrieder, Oliver; Burns, Kathleen H; Götte, Matthias; Rout, Michael P; Arnold, Eddy; Greenbaum, Benjamin D; Romero, Donna L; LaCava, John; Taylor, Martin S Nature 38096902 2024 Feb
B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Wu, Cheng-Guo; Balakrishnan, Vijaya K; Merrill, Ronald A; Parihar, Pankaj S; Konovolov, Kirill; Chen, Yu-Chia; Xu, Zhen; Wei, Hui; Sundaresan, Ramya; Cui, Qiang; Wadzinski, Brian E; Swingle, Mark R; Musiyenko, Alla; Chung, Wendy K; Honkanen, Richard E; Suzuki, Aussie; Huang, Xuhui; Strack, Stefan; Xing, Yongna Proceedings of the National Academy of Sciences of the United States of America 38150499 2024 Jan 02
The mating pilus of E. coli pED208 acts as a conduit for ssDNA during horizontal gene transfer. Beltrán, Leticia; Torsilieri, Holly; Patkowski, Jonasz B; Yang, Jie E; Casanova, James; Costa, Tiago R D; Wright, Elizabeth R; Egelman, Edward H mBio 38051116 2024 Jan 16
Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Padi, Sathish K R; Vos, Margaret R; Godek, Rachel J; Fuller, James R; Kruse, Thomas; Hein, Jamin B; Nilsson, Jakob; Kelker, Matthew S; Page, Rebecca; Peti, Wolfgang Nature 38123684 2024 Jan
Molecular basis of human trace amine-associated receptor 1 activation. Zilberg, Gregory; Parpounas, Alexandra K; Warren, Audrey L; Yang, Shifan; Wacker, Daniel Nature communications 38168118 2024 Jan 02
Cryo-EM structure and molecular dynamic simulations explain the enhanced stability and ATP activity of the pathological chaperonin mutant. Syed, Aiza; Zhai, Jihang; Guo, Baolin; Zhao, Yuan; Wang, Joseph Che-Yen; Chen, Lingling Structure (London, England : 1993) 38412855 2024 May 02
Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Nadezhdin, Kirill D; Correia, Leonor; Shalygin, Alexey; Aktolun, Muhammed; Neuberger, Arthur; Gudermann, Thomas; Kurnikova, Maria G; Chubanov, Vladimir; Sobolevsky, Alexander I Cell reports 38615321 2024 Apr 23
Molecular basis of proton-sensing by G protein-coupled receptors. Howard, Matthew K; Hoppe, Nicholas; Huang, Xi-Ping; Macdonald, Christian B; Mehrota, Eshan; Grimes, Patrick Rockefeller; Zahm, Adam; Trinidad, Donovan D; English, Justin; Coyote-Maestas, Willow; Manglik, Aashish bioRxiv : the preprint server for biology 38659943 2024 Apr 18
Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2. Hu, Wenxin; Song, Alex; Zheng, Hongjin Nature communications 38684689 2024 Apr 29
Functional and structural basis of human parainfluenza virus type 3 neutralization with human monoclonal antibodies. Suryadevara, Naveenchandra; Otrelo-Cardoso, Ana Rita; Kose, Nurgun; Hu, Yao-Xiong; Binshtein, Elad; Wolters, Rachael M; Greninger, Alexander L; Handal, Laura S; Carnahan, Robert H; Moscona, Anne; Jardetzky, Theodore S; Crowe Jr, James E Nature microbiology 38858594 2024 Aug
A stargate mechanism of Microviridae genome delivery unveiled by cryogenic electron tomography. Bardy, Pavol; MacDonald, Conor I W; Kirchberger, Paul C; Jenkins, Huw T; Botka, Tibor; Byrom, Lewis; Alim, Nawshin T B; Traore, Daouda A K; König, Hannah C; Nicholas, Tristan R; Chechik, Maria; Hart, Samuel J; Turkenburg, Johan P; Blaza, James N; Beatty, J Thomas; Fogg, Paul C M; Antson, Alfred A bioRxiv : the preprint server for biology 38915634 2024 Jun 11
Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy. Schnicker, Nicholas J; Xu, Zhen; Amir, Mohammad; Gakhar, Lokesh; Huang, Chou-Long bioRxiv : the preprint server for biology 38496408 2024 Mar 06
ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity. Nguyen, Binh An; Afrin, Shumaila; Yakubovska, Anna; Singh, Virender; Alicea, Jaime Vaquer; Kunach, Peter; Singh, Preeti; Pekala, Maja; Ahmed, Yasmin; Fernandez-Ramirez, Maria Del Carmen; Hernandez, Luis O Cabrera; Pedretti, Rose; Bassett, Parker; Wang, Lanie; Lemoff, Andrew; Villalon, Layla; Kluve-Beckerman, Barbara; Saelices, Lorena bioRxiv : the preprint server for biology 38798361 2024 May 14
Purification and Cryo-Electron Microscopy Analysis of Bacterial Appendages. Sanchez, Juan C; Baumgardt, Joseph K; Wright, Elizabeth R Bio-protocol 39100595 2024 Jul 20
Multi-layered heterochromatin interaction as a switch for DIM2-mediated DNA methylation. Shao, Zengyu; Lu, Jiuwei; Khudaverdyan, Nelli; Song, Jikui Nature communications 39122718 2024 Aug 09
Human calpain-3 and its structural plasticity: dissociation of a homohexamer into dimers on binding titin. Ye, Qilu; Henrickson, Amy; Demeler, Borries; Serrão, Vitor Hugo Balasco; Davies, Peter L bioRxiv : the preprint server for biology 38464089 2024 Mar 03
VitroJet: new features and case studies. Henderikx, Rene J M; Mann, Daniel; Domanska, Aušra; Dong, Jing; Shahzad, Saba; Lak, Behnam; Filopoulou, Aikaterini; Ludig, Damian; Grininger, Martin; Momoh, Jeffrey; Laanto, Elina; Oksanen, Hanna M; Bisikalo, Kyrylo; Williams, Pamela A; Butcher, Sarah J; Peters, Peter J; Beulen, Bart W A M M Acta crystallographica. Section D, Structural biology 38488730 2024 Apr 01
Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Driggers, Camden M; Kuo, Yi-Ying; Zhu, Phillip; ElSheikh, Assmaa; Shyng, Show-Ling Nature communications 38509107 2024 Mar 20
Multi-organ structural homogeneity of amyloid fibrils in ATTRv-T60A amyloidosis patients, revealed by Cryo-EM. Fernandez-Ramirez, Maria Del Carmen; Nguyen, Binh A; Singh, Virender; Afrin, Shumaila; Evers, Bret; Basset, Parker; Wang, Lanie; Pękała, Maja; Ahmed, Yasmin; Singh, Preeti; Canepa, Jacob; Wosztyl, Aleksandra; Li, Yang; Saelices, Lorena bioRxiv : the preprint server for biology 38798519 2024 May 14
Proton-coupled transport mechanism of the efflux pump NorA. Li, Jianping; Li, Yan; Koide, Akiko; Kuang, Huihui; Torres, Victor J; Koide, Shohei; Wang, Da-Neng; Traaseth, Nathaniel J Nature communications 38802368 2024 May 27
Mapping Protein-Protein Interactions at Birth: Single-Particle Cryo-EM Analysis of a Ribosome-Nascent Globin Complex. Masse, Meranda M; Hutchinson, Rachel B; Morgan, Christopher E; Allaman, Heather J; Guan, Hongqing; Yu, Edward W; Cavagnero, Silvia ACS central science 38435509 2024 Feb 28
Structures of the promoter-bound respiratory syncytial virus polymerase. Cao, Dongdong; Gao, Yunrong; Chen, Zhenhang; Gooneratne, Inesh; Roesler, Claire; Mera, Cristopher; D'Cunha, Paul; Antonova, Anna; Katta, Deepak; Romanelli, Sarah; Wang, Qi; Rice, Samantha; Lemons, Wesley; Ramanathan, Anita; Liang, Bo Nature 38123676 2024 Jan
Filament formation drives catalysis by glutaminase enzymes important in cancer progression. Feng, Shi; Aplin, Cody; Nguyen, Thuy-Tien T; Milano, Shawn K; Cerione, Richard A Nature communications 38438397 2024 Mar 04
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Atomic-level architecture of Caulobacter crescentus flagellar filaments provide evidence for multi-flagellin filament stabilization. Sanchez, Juan C; Montemayor, Eric J; Ploscariu, Nicoleta T; Parrell, Daniel; Baumgardt, Joseph K; Yang, Jie E; Sibert, Bryan; Cai, Kai; Wright, Elizabeth R bioRxiv : the preprint server for biology 37503001 2023 Jul 10
Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin. Neuberger, Arthur; Trofimov, Yury A; Yelshanskaya, Maria V; Khau, Jeffrey; Nadezhdin, Kirill D; Khosrof, Lena S; Krylov, Nikolay A; Efremov, Roman G; Sobolevsky, Alexander I Nature communications 37532722 2023 Aug 02
Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. Baier, Alexander S; Gioacchini, Nathan; Eek, Priit; Tan, Song; Peterson, Craig L Research square 37546845 2023 Jul 28
Extracellular filaments revealed by affinity capture cryo-electron tomography of lymphocytes. Engel, Leeya; Zaoralova, Magda; Dunn, Alexander R; Oliver, Stefan bioRxiv : the preprint server for biology 37577490 2023 Aug 06
Structural insights into opposing actions of neurosteroids on GABAA receptors. Legesse, Dagimhiwat H; Fan, Chen; Teng, Jinfeng; Zhuang, Yuxuan; Howard, Rebecca J; Noviello, Colleen M; Lindahl, Erik; Hibbs, Ryan E Nature communications 37607940 2023 Aug 22
Developing Technologies for Correlative Cryo-Imaging Pipelines. Wright, Elizabeth R; Yang, Jae; Sibert, Bryan; Larson, Matthew; Kim, Joseph Y; Parrell, Daniel; Sanchez, Juan C; Kumar, Anil; Cai, Kai Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 37613235 2023 Jul 22
The National Center for CryoEM Access and Training - Establishing a Cross-Facility-Honored Training Curriculum. Eng, Edward T; Zimanyi, Christina; Aragon, Mahira; Chua, Eugene Y D; Kopylov, Elina; Dubbeldam, Charlie; Castello, Cathleen; Kieft, Jeffrey S; de Marco, Alex Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 37613291 2023 Jul 22
Cryo-EM Pipeline for Pharmaceutical and Biotechnology Industries. Kumar, Anil; Cai, Kai; Larson, Matt R; Sibert, Bryan S; Yang, Jae E; Wright, Elizabeth R Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 37613370 2023 Jul 22
Structural and Functional Analysis of Flagellar Filaments of Caulobacter crescentus. Sanchez, Juan C; Montemayor, Eric J; Ploscariu, Nicoleta T; Parrell, Daniel D; Yang, Jae; Sibert, Bryan; Cai, Kai; Wright, Elizabeth R Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 37613764 2023 Jul 22
Workflow for High-resolution Sub-volume Averaging from Heterogenous Viral and Virus-like Assemblies. Sibert, Bryan S; Kim, Joseph Y; Yang, Jae E; Hannon-Hatfield, Adam; Ke, Zunlong; Garfinkel, David J; Wright, Elizabeth R Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 37613807 2023 Jul 22
CryoEM structures of the human CLC-2 voltage gated chloride channel reveal a ball and chain gating mechanism. Xu, Mengyuan; Neelands, Torben; Powers, Alexander S; Liu, Yan; Miller, Steven D; Pintilie, Grigore; Bois, J Du; Dror, Ron O; Chiu, Wah; Maduke, Merritt bioRxiv : the preprint server for biology 37645939 2023 Nov 29
Modulation of GluA2-γ5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Gangwar, Shanti Pal; Yen, Laura Y; Yelshanskaya, Maria V; Korman, Aryeh; Jones, Drew R; Sobolevsky, Alexander I Nature structural & molecular biology 37653241 2023 Oct
The Structures of Secretory IgA in complex with Streptococcus pyogenes M4 and human CD89 provide insights on mucosal host-pathogen interactions. Liu, Qianqiao; Stadtmueller, Beth M bioRxiv : the preprint server for biology 37662389 2023 Aug 26
Substrate binding and inhibition of the anion exchanger 1 transporter. Capper, Michael J; Yang, Shifan; Stone, Alexander C; Vatansever, Sezen; Zilberg, Gregory; Mathiharan, Yamuna Kalyani; Habib, Raul; Hutchinson, Keino; Zhao, Yihan; Schlessinger, Avner; Mezei, Mihaly; Osman, Roman; Zhang, Bin; Wacker, Daniel Nature structural & molecular biology 37679563 2023 Oct
Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Padi, Sathish K R; Vos, Margaret R; Godek, Rachel J; Fuller, James R; Kruse, Thomas; Hein, Jamin B; Nilsson, Jakob; Kelker, Matthew S; Page, Rebecca; Peti, Wolfgang bioRxiv : the preprint server for biology 37693408 2023 Aug 31
Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron. Patel, Anamika; Kumar, Sanjeev; Lai, Lilin; Keen, Meredith; Valanparambil, Rajesh; Chakravarthy, Chennareddy; Laughlin, Zane; Frank, Filipp; Cheedarla, Narayanaiah; Verkerke, Hans P; Neish, Andrew S; Roback, John D; Davis, Carl W; Wrammert, Jens; Sharma, Amit; Ahmed, Rafi; Suthar, Mehul S; Murali-Krishna, Kaja; Chandele, Anmol; Ortlund, Eric Cell reports 37708028 2023 Sep 26
Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays. Santiago-Frangos, Andrew; Henriques, William S; Wiegand, Tanner; Gauvin, Colin C; Buyukyoruk, Murat; Graham, Ava B; Wilkinson, Royce A; Triem, Lenny; Neselu, Kasahun; Eng, Edward T; Lander, Gabriel C; Wiedenheft, Blake Nature structural & molecular biology 37710013 2023 Nov
Correlative montage parallel array cryo-tomography for in situ structural cell biology. Yang, Jie E; Larson, Matthew R; Sibert, Bryan S; Kim, Joseph Y; Parrell, Daniel; Sanchez, Juan C; Pappas, Victoria; Kumar, Anil; Cai, Kai; Thompson, Keith; Wright, Elizabeth R Nature methods 37723245 2023 Oct
Cryo-EM structures reveal native GABAA receptor assemblies and pharmacology. Sun, Chang; Zhu, Hongtao; Clark, Sarah; Gouaux, Eric Nature 37730991 2023 Oct
Structural Mechanisms for VMAT2 inhibition by tetrabenazine. Dalton, Michael P; Cheng, Mary Hongying; Bahar, Ivet; Coleman, Jonathan A bioRxiv : the preprint server for biology 37732203 2023 Sep 05
Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus. Velez, Michael; Mietzsch, Mario; Hsi, Jane; Bell, Logan; Chipman, Paul; Fu, Xiaofeng; McKenna, Robert Viruses 37766206 2023 Aug 24
C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. Consalvo, Claudia D; Aderounmu, Adedeji M; Donelick, Helen M; Aruscavage, P Joe; Eckert, Debra M; Shen, Peter S; Bass, Brenda L bioRxiv : the preprint server for biology 37790392 2023 Oct 26
Mobile barrier mechanisms for Na+-coupled symport in an MFS sugar transporter. Hariharan, Parameswaran; Shi, Yuqi; Katsube, Satoshi; Willibal, Katleen; Burrows, Nathan D; Mitchell, Patrick; Bakhtiiari, Amirhossein; Stanfield, Samantha; Pardon, Els; Kaback, H Ronald; Liang, Ruibin; Steyaert, Jan; Viner, Rosa; Guan, Lan bioRxiv : the preprint server for biology 37790566 2023 Nov 25
A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM. Langeberg, Conner J; Kieft, Jeffrey S Nucleic acids research 37791881 2023 Nov 10
Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN Domain. Small, Gabriel I; Fedorova, Olga; Olinares, Paul Dominic B; Chandanani, Joshua; Banerjee, Anoosha; Choi, Young Joo; Molina, Henrik; Chait, Brian; Darst, Seth A; Campbell, Elizabeth A bioRxiv : the preprint server for biology 37808858 2023 Sep 26
Structural Determination of Glucosyltransferase C by Cryo-Electron Microscopy. Xie, Qing; Cao, Jianhao; Zhang, Hua; Wu, Hui Methods in molecular biology (Clifton, N.J.) 37815721 2024
Scaling up cryo-EM for biology and chemistry: The journey from niche technology to mainstream method. de la Cruz, M Jason; Eng, Edward T Structure (London, England : 1993) 37820731 2023 Dec 07
Structural basis of promiscuous substrate transport by Organic Cation Transporter 1. Zeng, Yi C; Sobti, Meghna; Quinn, Ada; Smith, Nicola J; Brown, Simon H J; Vandenberg, Jamie I; Ryan, Renae M; O'Mara, Megan L; Stewart, Alastair G Nature communications 37821493 2023 Oct 11
High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology. Zhang, Zhemin; Tringides, Marios L; Morgan, Christopher E; Miyagi, Masaru; Mears, Jason A; Hoppel, Charles L; Yu, Edward W Molecular & cellular proteomics : MCP 37839702 2023 Dec
Accurate computational design of three-dimensional protein crystals. Li, Zhe; Wang, Shunzhi; Nattermann, Una; Bera, Asim K; Borst, Andrew J; Yaman, Muammer Y; Bick, Matthew J; Yang, Erin C; Sheffler, William; Lee, Byeongdu; Seifert, Soenke; Hura, Greg L; Nguyen, Hannah; Kang, Alex; Dalal, Radhika; Lubner, Joshua M; Hsia, Yang; Haddox, Hugh; Courbet, Alexis; Dowling, Quinton; Miranda, Marcos; Favor, Andrew; Etemadi, Ali; Edman, Natasha I; Yang, Wei; Weidle, Connor; Sankaran, Banumathi; Negahdari, Babak; Ross, Michael B; Ginger, David S; Baker, David Nature materials 37845322 2023 Dec
SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions. Liu, Qianqiao; Stadtmueller, Beth M Nature communications 37872175 2023 Oct 23
A Suite of Designed Protein Cages Using Machine Learning Algorithms and Protein Fragment-Based Protocols. Meador, Kyle; Castells-Graells, Roger; Aguirre, Roman; Sawaya, Michael R; Arbing, Mark A; Sherman, Trent; Senarathne, Chethaka; Yeates, Todd O bioRxiv : the preprint server for biology 37873110 2023 Oct 09
Fabrication of membrane proteins in the form of native cell membrane nanoparticles using novel membrane active polymers. Hoang Trinh, Thi Kim; Catalano, Claudio; Guo, Youzhong Nanoscale advances 37881706 2023 Oct 24
Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Small, Gabriel I; Fedorova, Olga; Olinares, Paul Dominic B; Chandanani, Joshua; Banerjee, Anoosha; Choi, Young Joo; Molina, Henrik; Chait, Brian T; Darst, Seth A; Campbell, Elizabeth A Molecular cell 37890482 2023 Nov 02
Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions. Li, Shibai; Yu, You; Zheng, Jian; Miller-Browne, Victoria; Ser, Zheng; Kuang, Huihui; Patel, Dinshaw J; Zhao, Xiaolan Proceedings of the National Academy of Sciences of the United States of America 37903273 2023 Nov 07
Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP. Hussein, Adel; Fan, Shujie; Lopez-Redondo, Maria; Kenney, Ian; Zhang, Xihui; Beckstein, Oliver; Stokes, David L eLife 37906094 2023 Oct 31
Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Lu, Jiuwei; Fang, Jian; Zhu, Hongtao; Liang, Kimberly Lu; Khudaverdyan, Nelli; Song, Jikui Nucleic acids research 37941146 2023 Dec 11
Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. Iglesias, Stephano M; Lokareddy, Ravi K; Yang, Ruoyu; Li, Fenglin; Yeggoni, Daniel P; David Hou, Chun-Feng; Leroux, Makayla N; Cortines, Juliana R; Leavitt, Justin C; Bird, Mary; Casjens, Sherwood R; White, Simon; Teschke, Carolyn M; Cingolani, Gino Journal of molecular biology 37952769 2023 Dec 15
Cryo-electron tomography reveals the structural diversity of cardiac proteins in their cellular context. Woldeyes, Rahel A; Nishiga, Masataka; Vander Roest, Alison S; Engel, Leeya; Giri, Prerna; Montenegro, Gabrielle C; Wu, Andrew C; Dunn, Alexander R; Spudich, James A; Bernstein, Daniel; Schmid, Michael F; Wu, Joseph C; Chiu, Wah bioRxiv : the preprint server for biology 37961228 2023 Oct 26
Molecular Basis of Human Trace Amine-Associated Receptor 1 Activation. Zilberg, Gregory; Parpounas, Alexandra K; Warren, Audrey L; Yang, Shifan; Wacker, Daniel bioRxiv : the preprint server for biology 37986760 2023 Sep 07
Structural Insights into the Unexpected Agonism of Tetracyclic Antidepressants at Serotonin Receptors 5-HT1eR and 5-HT1FR. Zilberg, Gregory; Parpounas, Alexandra K; Warren, Audrey L; Fiorillo, Bianca; Provasi, Davide; Filizola, Marta; Wacker, Daniel bioRxiv : the preprint server for biology 37986777 2023 Oct 07
Tad and toxin-coregulated pilus structures reveal unexpected diversity in bacterial type IV pili. Sonani, Ravi R; Sanchez, Juan Carlos; Baumgardt, Joseph K; Kundra, Shivani; Wright, Elizabeth R; Craig, Lisa; Egelman, Edward H Proceedings of the National Academy of Sciences of the United States of America 38011558 2023 Dec 05
Engineered odorant receptors illuminate structural principles of odor discrimination. de March, Claire A; Ma, Ning; Billesbølle, Christian B; Tewari, Jeevan; Del Torrent, Claudia Llinas; van der Velden, Wijnand J C; Ojiro, Ichie; Takayama, Ikumi; Faust, Bryan; Li, Linus; Vaidehi, Nagarajan; Manglik, Aashish; Matsunami, Hiroaki bioRxiv : the preprint server for biology 38014344 2023 Nov 17
Structural basis for flagellin-induced NAIP5 activation. Paidimuddala, Bhaskar; Cao, Jianhao; Zhang, Liman Science advances 38055825 2023 Dec 08
Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Kretsch, Rachael C; Xu, Lily; Zheludev, Ivan N; Zhou, Xueting; Huang, Rui; Nye, Grace; Li, Shanshan; Zhang, Kaiming; Chiu, Wah; Das, Rhiju bioRxiv : the preprint server for biology 38076883 2023 Nov 27
Structural dynamics of GluK2 kainate receptors in apo and partial agonist bound states. Bogdanović, Nebojša; Segura-Covarrubias, Guadalupe; Zhang, Lisa; Tajima, Nami Research square 38076992 2023 Dec 02
Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. Rosenberg, Gregory M; Abskharon, Romany; Boyer, David R; Ge, Peng; Sawaya, Michael R; Eisenberg, David S PNAS nexus 38077690 2023 Dec
A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Oh, Juntaek; Shan, Zelin; Hoshika, Shuichi; Xu, Jun; Chong, Jenny; Benner, Steven A; Lyumkis, Dmitry; Wang, Dong Nature communications 38086811 2023 Dec 12
Structures of the promoter-bound respiratory syncytial virus polymerase. Cao, Dongdong; Gao, Yunrong; Chen, Zhenhang; Gooneratne, Inesh; Roesler, Claire; Mera, Cristopher; D'Cunha, Paul; Antonova, Anna; Katta, Deepak; Romanelli, Sarah; Wang, Qi; Rice, Samantha; Lemons, Wesley; Ramanathan, Anita; Liang, Bo Nature 38123676 2023 Dec 20
Product analog binding identifies the copper active site of particulate methane monooxygenase. Tucci, Frank J; Jodts, Richard J; Hoffman, Brian M; Rosenzweig, Amy C Nature catalysis 38187819 2023 Dec
Recent advances in infectious disease research using cryo-electron tomography. Asarnow, Daniel; Becker, Vada A; Bobe, Daija; Dubbledam, Charlie; Johnston, Jake D; Kopylov, Mykhailo; Lavoie, Nathalie R; Li, Qiuye; Mattingly, Jacob M; Mendez, Joshua H; Paraan, Mohammadreza; Turner, Jack; Upadhye, Viraj; Walsh Jr, Richard M; Gupta, Meghna; Eng, Edward T Frontiers in molecular biosciences 38288336 2023
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Hoppe, Nicholas; Harrison, Simone; Hwang, Sun-Hee; Chen, Ziwei; Karelina, Masha; Deshpande, Ishan; Suomivuori, Carl-Mikael; Palicharla, Vivek R; Berry, Samuel P; Tschaikner, Philipp; Regele, Dominik; Covey, Douglas F; Stefan, Eduard; Marks, Debora S; Reiter, Jeremy F; Dror, Ron O; Evers, Alex S; Mukhopadhyay, Saikat; Manglik, Aashish Nature structural & molecular biology 38326651 2024 Feb 07
CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization. Serbynovskyi, Viacheslav; Wang, Jing; Chua, Eugene Yd; Ishemgulova, Aygul; Alink, Lambertus M; Budell, William C; Johnston, Jake D; Dubbeldam, Charlie; Gonzalez, Fabio A; Rozovsky, Sharon; Eng, Edward T; de Marco, Alex; Noble, Alex J bioRxiv : the preprint server for biology 38328036 2024 Feb 01
Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor. Mazzaferro, Simone; Kang, Guipeun; Natarajan, Kathiresan; Hibbs, Ryan E; Sine, Steven M British journal of pharmacology 38454578 2024 Mar 07

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