Absolute structure determination of Berkecoumarin by X-ray and electron diffraction. |
Decato, Daniel; Palatinus, Lukáš; Stierle, Andrea; Stierle, Donald |
Acta crystallographica. Section C, Structural chemistry |
38598330 |
2024 May 01 |
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. |
Held, Richard G; Liang, Jiahao; Brunger, Axel T |
Proceedings of the National Academy of Sciences of the United States of America |
38923992 |
2024 Jul 02 |
Structural mechanisms for VMAT2 inhibition by tetrabenazine. |
Dalton, Michael P; Cheng, Mary Hongying; Bahar, Ivet; Coleman, Jonathan A |
bioRxiv : the preprint server for biology |
37732203 |
2024 Feb 01 |
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. |
Hoppe, Nicholas; Harrison, Simone; Hwang, Sun-Hee; Chen, Ziwei; Karelina, Masha; Deshpande, Ishan; Suomivuori, Carl-Mikael; Palicharla, Vivek R; Berry, Samuel P; Tschaikner, Philipp; Regele, Dominik; Covey, Douglas F; Stefan, Eduard; Marks, Debora S; Reiter, Jeremy F; Dror, Ron O; Evers, Alex S; Mukhopadhyay, Saikat; Manglik, Aashish |
Nature structural & molecular biology |
38326651 |
2024 Apr |
CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization. |
Serbynovskyi, Viacheslav; Wang, Jing; Chua, Eugene Yd; Ishemgulova, Aygul; Alink, Lambertus M; Budell, William C; Johnston, Jake D; Dubbeldam, Charlie; Gonzalez, Fabio A; Rozovsky, Sharon; Eng, Edward T; de Marco, Alex; Noble, Alex J |
bioRxiv : the preprint server for biology |
38328036 |
2024 May 13 |
Miffi: Improving the accuracy of CNN-based cryo-EM micrograph filtering with fine-tuning and Fourier space information. |
Xu, Da; Ando, Nozomi |
bioRxiv : the preprint server for biology |
38405773 |
2024 Feb 27 |
Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. |
Kretsch, Rachael C; Xu, Lily; Zheludev, Ivan N; Zhou, Xueting; Huang, Rui; Nye, Grace; Li, Shanshan; Zhang, Kaiming; Chiu, Wah; Das, Rhiju |
Proceedings of the National Academy of Sciences of the United States of America |
38427602 |
2024 Mar 05 |
Mobile barrier mechanisms for Na+-coupled symport in an MFS sugar transporter. |
Hariharan, Parameswaran; Shi, Yuqi; Katsube, Satoshi; Willibal, Katleen; Burrows, Nathan D; Mitchell, Patrick; Bakhtiiari, Amirhossein; Stanfield, Samantha; Pardon, Els; Kaback, H Ronald; Liang, Ruibin; Steyaert, Jan; Viner, Rosa; Guan, Lan |
eLife |
38381130 |
2024 Feb 21 |
Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation. |
Burke, Sean M; Avstrikova, Mariia; Noviello, Colleen M; Mukhtasimova, Nuriya; Changeux, Jean-Pierre; Thakur, Ganesh A; Sine, Steven M; Cecchini, Marco; Hibbs, Ryan E |
Cell |
38382524 |
2024 Feb 29 |
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. |
Nguyen, Binh An; Singh, Virender; Afrin, Shumaila; Yakubovska, Anna; Wang, Lanie; Ahmed, Yasmin; Pedretti, Rose; Fernandez-Ramirez, Maria Del Carmen; Singh, Preeti; Pękała, Maja; Cabrera Hernandez, Luis O; Kumar, Siddharth; Lemoff, Andrew; Gonzalez-Prieto, Roman; Sawaya, Michael R; Eisenberg, David S; Benson, Merrill Douglas; Saelices, Lorena |
Nature communications |
38233397 |
2024 Jan 17 |
Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor. |
Mazzaferro, Simone; Kang, Guipeun; Natarajan, Kathiresan; Hibbs, Ryan E; Sine, Steven M |
British journal of pharmacology |
38454578 |
2024 Jul |
Mechanisms of RNF168 nucleosome recognition and ubiquitylation. |
Hu, Qi; Zhao, Debiao; Cui, Gaofeng; Bhandari, Janarjan; Thompson, James R; Botuyan, Maria Victoria; Mer, Georges |
Molecular cell |
38242129 |
2024 Mar 07 |
Structures of the essential efflux pump EfpA from Mycobacterium tuberculosis reveal the mechanisms of substrate transport and small-molecule inhibition. |
Wang, Shuhui; Wang, Kun; Song, Kangkang; Li, Pengfei; Li, Dongying; Sun, Yajie; Mei, Ye; Xu, Chen; Liao, Maofu |
Research square |
38260587 |
2024 Jan 05 |
Cryo-EM Structure of AAV2 Rep68 bound to integration site AAVS1: Insights into the mechanism of DNA melting. |
Jaiswal, R; Santosh, V; Braud, B; Washington, A; Escalante, Carlos R |
bioRxiv : the preprint server for biology |
38617369 |
2024 Apr 02 |
Structural mechanisms for VMAT2 inhibition by tetrabenazine. |
Dalton, Michael P; Cheng, Mary Hongying; Bahar, Ivet; Coleman, Jonathan A |
eLife |
38517752 |
2024 Mar 22 |
Dramatic Changes in Mitochondrial Subcellular Location and Morphology Accompany Activation of the CO2 Concentrating Mechanism. |
Findinier, Justin; Joubert, Lydia-Marie; Schmid, Michael F; Malkovskiy, Andrey; Chiu, Wah; Burlacot, Adrien; Grossman, Arthur R |
bioRxiv : the preprint server for biology |
38585955 |
2024 Mar 27 |
Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination. |
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bioRxiv : the preprint server for biology |
38464151 |
2024 Mar 01 |
Blueprinting extendable nanomaterials with standardized protein blocks. |
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Nature |
38480887 |
2024 Mar |
Protocol to study CCT-mediated folding of Gβ5 by single-particle cryo-EM. |
Sass, Mikaila I; Wang, Shuxin; Mack, Deirdre; Cottam, Samuel L; Shen, Peter S; Willardson, Barry M |
STAR protocols |
38848218 |
2024 Jun 21 |
Structural basis for inhibition of coagulation factor VIII reveals a shared antigenic hotspot on the C1 domain. |
Childers, Kenneth C; Cowper, Ben; Vaughan, Jordan D; McGill, Juliet R; Davulcu, Omar; Lollar, Pete; Doering, Christopher B; Coxon, Carmen H; Spiegel Jr, Paul C |
Journal of thrombosis and haemostasis : JTH |
38849084 |
2024 Sep |
Structural basis for Retriever-SNX17 assembly and endosomal sorting. |
Singla, Amika; Boesch, Daniel J; Joyce Fung, Ho Yee; Ngoka, Chigozie; Enriquez, Avery S; Song, Ran; Kramer, Daniel A; Han, Yan; Juneja, Puneet; Billadeau, Daniel D; Bai, Xiaochen; Chen, Zhe; Turer, Emre E; Burstein, Ezra; Chen, Baoyu |
bioRxiv : the preprint server for biology |
38559023 |
2024 Mar 13 |
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. |
Edman, Natasha I; Phal, Ashish; Redler, Rachel L; Schlichthaerle, Thomas; Srivatsan, Sanjay R; Ehnes, Devon Duron; Etemadi, Ali; An, Seong J; Favor, Andrew; Li, Zhe; Praetorius, Florian; Gordon, Max; Vincent, Thomas; Marchiano, Silvia; Blakely, Leslie; Lin, Chuwei; Yang, Wei; Coventry, Brian; Hicks, Derrick R; Cao, Longxing; Bethel, Neville; Heine, Piper; Murray, Analisa; Gerben, Stacey; Carter, Lauren; Miranda, Marcos; Negahdari, Babak; Lee, Sangwon; Trapnell, Cole; Zheng, Ying; Murry, Charles E; Schweppe, Devin K; Freedman, Benjamin S; Stewart, Lance; Ekiert, Damian C; Schlessinger, Joseph; Shendure, Jay; Bhabha, Gira; Ruohola-Baker, Hannele; Baker, David |
Cell |
38861993 |
2024 Jul 11 |
Multi-species cryoEM calibration and workflow verification standard. |
Bobe, Daija; Kopylov, Mykhailo; Miller, Jessalyn; Owji, Aaron P; Eng, Edward T |
bioRxiv : the preprint server for biology |
39149318 |
2024 Aug 05 |
Preparing research samples for safe arrival at centers and facilities: recipes for successful experiments. |
Bowman, Sarah E J; Byrnes, James; Russi, Silvia; Zimanyi, Christina M |
Acta crystallographica. Section F, Structural biology communications |
38990054 |
2024 Aug 01 |
CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization. |
Serbynovskyi, Viacheslav; Wang, Jing; Chua, Eugene Yd; Ishemgulova, Aygul; Alink, Lambertus M; Budell, William C; Johnston, Jake D; Dubbeldam, Charlie; Gonzalez, Fabio A; Rozovsky, Sharon; Eng, Edward T; de Marco, Alex; Noble, Alex J |
Research square |
39011111 |
2024 Jul 02 |
High-affinity agonism at the P2X7 receptor is mediated by three residues outside the orthosteric pocket. |
Oken, Adam C; Lisi, Nicolas E; Krishnamurthy, Ipsita; McCarthy, Alanna E; Godsey, Michael H; Glasfeld, Arthur; Mansoor, Steven E |
Nature communications |
39107314 |
2024 Aug 06 |
Structure of the human dopamine transporter and mechanisms of inhibition. |
Srivastava, Dushyant Kumar; Navratna, Vikas; Tosh, Dilip K; Chinn, Audrey; Sk, Md Fulbabu; Tajkhorshid, Emad; Jacobson, Kenneth A; Gouaux, Eric |
Nature |
39112705 |
2024 Aug |
C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. |
Consalvo, Claudia D; Aderounmu, Adedeji M; Donelick, Helen M; Aruscavage, P Joe; Eckert, Debra M; Shen, Peter S; Bass, Brenda L |
bioRxiv : the preprint server for biology |
37790392 |
2024 Jan 24 |
Structural Determination of Glucosyltransferase C by Cryo-Electron Microscopy. |
Xie, Qing; Cao, Jianhao; Zhang, Hua; Wu, Hui |
Methods in molecular biology (Clifton, N.J.) |
37815721 |
2024 |
Activation of human STING by a molecular glue-like compound. |
Li, Jie; Canham, Stephen M; Wu, Hua; Henault, Martin; Chen, Lihao; Liu, Guoxun; Chen, Yu; Yu, Gary; Miller, Howard R; Hornak, Viktor; Brittain, Scott M; Michaud, Gregory A; Tutter, Antonin; Broom, Wendy; Digan, Mary Ellen; McWhirter, Sarah M; Sivick, Kelsey E; Pham, Helen T; Chen, Christine H; Tria, George S; McKenna, Jeffery M; Schirle, Markus; Mao, Xiaohong; Nicholson, Thomas B; Wang, Yuan; Jenkins, Jeremy L; Jain, Rishi K; Tallarico, John A; Patel, Sejal J; Zheng, Lianxing; Ross, Nathan T; Cho, Charles Y; Zhang, Xuewu; Bai, Xiao-Chen; Feng, Yan |
Nature chemical biology |
37828400 |
2024 Mar |
Structural basis of Gabija anti-phage defence and viral immune evasion. |
Antine, Sadie P; Johnson, Alex G; Mooney, Sarah E; Leavitt, Azita; Mayer, Megan L; Yirmiya, Erez; Amitai, Gil; Sorek, Rotem; Kranzusch, Philip J |
Nature |
37992757 |
2024 Jan |
CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. |
Xu, Mengyuan; Neelands, Torben; Powers, Alexander S; Liu, Yan; Miller, Steven D; Pintilie, Grigore D; Bois, J Du; Dror, Ron O; Chiu, Wah; Maduke, Merritt |
eLife |
38345841 |
2024 Feb 12 |
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications. |
Cookis, Trinity; Lydecker, Alexandria; Sauer, Paul; Kasinath, Vignesh; Nogales, Eva |
bioRxiv : the preprint server for biology |
38370759 |
2024 Feb 10 |
An in vitro experimental pipeline to characterize the epitope of a SARS-CoV-2 neutralizing antibody. |
Atanasoff, Kristina E; Brambilla, Luca; Adelsberg, Daniel C; Kowdle, Shreyas; Stevens, Christian S; Slamanig, Stefan; Hung, Chuan-Tien; Fu, Yanwen; Lim, Reyna; Tran, Linh; Allen, Robert; Sun, Weina; Duty, J Andrew; Bajic, Goran; Lee, Benhur; Tortorella, Domenico |
mBio |
38054729 |
2024 Jan 16 |
Mechanism of anion exchange and small-molecule inhibition of pendrin. |
Wang, Lie; Hoang, Anthony; Gil-Iturbe, Eva; Laganowsky, Arthur; Quick, Matthias; Zhou, Ming |
Nature communications |
38184688 |
2024 Jan 06 |
Miffi: Improving the accuracy of CNN-based cryo-EM micrograph filtering with fine-tuning and Fourier space information. |
Xu, Da; Ando, Nozomi |
Journal of structural biology |
38431179 |
2024 Jun |
Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. |
Yang, Ruoyu; Ko, Ying-Hui; Li, Fenglin; Lokareddy, Ravi K; Hou, Chun-Feng David; Kim, Christine; Klein, Shelby; Antolínez, Santiago; Marín, Juan F; Pérez-Segura, Carolina; Jarrold, Martin F; Zlotnick, Adam; Hadden-Perilla, Jodi A; Cingolani, Gino |
Science advances |
38198557 |
2024 Jan 12 |
Cryo-EM analysis of Pseudomonas phage Pa193 structural components. |
Cingolani, Gino; Iglesias, Stephano; Hou, Chun-Feng; Lemire, Sebastien; Soriaga, Angela; Kyme, Pierre |
Research square |
38659960 |
2024 Apr 12 |
Applying 3D ED/MicroED workflows toward the next frontiers. |
Aragon, Mahira; Bowman, Sarah E J; Chen, Chun Hsing; de la Cruz, M Jason; Decato, Daniel A; Eng, Edward T; Flatt, Kristen M; Gulati, Sahil; Li, Yuchen; Lomba, Charles J; Mercado, Brandon; Miller, Jessalyn; Palatinus, Lukáš; Rice, William J; Waterman, David; Zimanyi, Christina M |
Acta crystallographica. Section C, Structural chemistry |
38712546 |
2024 Jun 01 |
Structural transitions enable interleukin-18 maturation and signaling. |
Dong, Ying; Bonin, Jeffrey P; Devant, Pascal; Liang, Zhuoyi; Sever, Alexander I M; Mintseris, Julian; Aramini, James M; Du, Gang; Gygi, Stephen P; Kagan, Jonathan C; Kay, Lewis E; Wu, Hao |
Immunity |
38733997 |
2024 Jul 09 |
Caenorhabditis elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. |
Consalvo, Claudia D; Aderounmu, Adedeji M; Donelick, Helen M; Aruscavage, P Joseph; Eckert, Debra M; Shen, Peter S; Bass, Brenda L |
eLife |
38747717 |
2024 May 15 |
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. |
Eisenberg, David; Hou, Ke; Ge, Peng; Sawaya, Michael; Dolinsky, Joshua; Yang, Yuan; Jiang, Yi Xiao; Lutter, Liisa; Boyer, David; Cheng, Xinyi; Pi, Justin; Zhang, Jeffrey; Lu, Jiahui; Yang, Shixin; Yu, Zhiheng; Feigon, Juli |
Research square |
38766197 |
2024 May 08 |
Amyloid fibril polymorphism in the heart of an ATTR amyloidosis patient with polyneuropathy attributed to the V122Δ variant. |
Ahmed, Yasmin; Nguyen, Binh An; Afrin, Shumaila; Singh, Virender; Evers, Bret; Singh, Preeti; Pedretti, Rose; Wang, Lanie; Bassett, Parker; Del Carmen Fernandez-Ramirez, Maria; Pekala, Maja; Kluve-Beckerman, Barbara; Saelices, Lorena |
bioRxiv : the preprint server for biology |
38766262 |
2024 May 10 |
Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. |
Baier, Alexander S; Gioacchini, Nathan; Eek, Priit; Leith, Erik M; Tan, Song; Peterson, Craig L |
eLife |
38809771 |
2024 May 29 |
Mechanisms of actin filament severing and elongation by formins. |
Palmer, Nicholas J; Barrie, Kyle R; Dominguez, Roberto |
Nature |
38843827 |
2024 Aug |
Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens. |
Brown, Sharidan; Antanasijevic, Aleksandar; Sewall, Leigh M; Garcia, Daniel Montiel; Brouwer, Philip J M; Sanders, Rogier W; Ward, Andrew B |
bioRxiv : the preprint server for biology |
38559180 |
2024 Mar 17 |
Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. |
Erramilli, Satchal K; Dominik, Pawel K; Ogbu, Chinemerem P; Kossiakoff, Anthony A; Vecchio, Alex J |
Communications biology |
38886509 |
2024 Jun 17 |
Hub stability in the calcium calmodulin-dependent protein kinase II. |
Chien, Chih-Ta; Puhl, Henry; Vogel, Steven S; Molloy, Justin E; Chiu, Wah; Khan, Shahid |
Communications biology |
38918547 |
2024 Jun 25 |
Structural and Biochemical Characterization of the Nucleosome Containing Variants H3.3 and H2A.Z. |
Jung, Harry; Sokolova, Vladyslava; Lee, Gahyun; Stevens, Victoria Rose; Tan, Dongyan |
Epigenomes |
38920622 |
2024 May 27 |
Dynamic fibrillar assembly of αB-crystallin induced by perturbation of the conserved NT-IXI motif resolved by cryo-EM. |
McFarland, Russell; Reichow, Steve |
bioRxiv : the preprint server for biology |
38585788 |
2024 Mar 27 |
Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor. |
Cingolani, Gino; Lokareddy, Ravi; Hou, Chun-Feng; Forti, Francesca; Iglesias, Stephano; Li, Fenglin; Pavlenok, Mikhail; Niederweis, Michael; Briani, Federica |
Research square |
38463957 |
2024 Feb 21 |
Kainate receptor channel opening and gating mechanism. |
Gangwar, Shanti Pal; Yelshanskaya, Maria V; Nadezhdin, Kirill D; Yen, Laura Y; Newton, Thomas P; Aktolun, Muhammed; Kurnikova, Maria G; Sobolevsky, Alexander I |
Nature |
38778115 |
2024 Jun |
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis. |
Nguyen, Binh An; Singh, Virender; Afrin, Shumaila; Singh, Preeti; Pekala, Maja; Ahmed, Yasmin; Pedretti, Rose; Canepa, Jacob; Lemoff, Andrew; Kluve-Beckerman, Barbara; Wydorski, Pawel; Chhapra, Farzeen; Saelices, Lorena |
bioRxiv : the preprint server for biology |
38496656 |
2024 Mar 09 |
A suite of designed protein cages using machine learning and protein fragment-based protocols. |
Meador, Kyle; Castells-Graells, Roger; Aguirre, Roman; Sawaya, Michael R; Arbing, Mark A; Sherman, Trent; Senarathne, Chethaka; Yeates, Todd O |
Structure (London, England : 1993) |
38513658 |
2024 Jun 06 |
Cryo-EM sample preparation for high-resolution structure studies. |
Wang, Liguo; Zimanyi, Christina M |
Acta crystallographica. Section F, Structural biology communications |
38530656 |
2024 Apr 01 |
Structures of the Mycobacterium tuberculosis efflux pump EfpA reveal the mechanisms of transport and inhibition. |
Wang, Shuhui; Wang, Kun; Song, Kangkang; Lai, Zon Weng; Li, Pengfei; Li, Dongying; Sun, Yajie; Mei, Ye; Xu, Chen; Liao, Maofu |
Nature communications |
39231991 |
2024 Sep 04 |
Assembly of respiratory syncytial virus matrix protein lattice and its coordination with fusion glycoprotein trimers. |
Sibert, Bryan S; Kim, Joseph Y; Yang, Jie E; Ke, Zunlong; Stobart, Christopher C; Moore, Martin L; Wright, Elizabeth R |
Nature communications |
39004634 |
2024 Jul 14 |
Structural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction. |
Chen, Xinyi; Guo, Yiran; Zhao, Ting; Lu, Jiuwei; Fang, Jian; Wang, Yinsheng; Wang, Gang Greg; Song, Jikui |
Nature communications |
39043678 |
2024 Jul 23 |
Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore. |
Gao, Xiaolong; Yeh, Han-I; Yang, Zhengrong; Fan, Chen; Jiang, Fan; Howard, Rebecca J; Lindahl, Erik; Kappes, John C; Hwang, Tzyh-Chang |
Nature communications |
39107303 |
2024 Aug 06 |
Structural bases for Na+-Cl- cotransporter inhibition by thiazide diuretic drugs and activation by kinases. |
Zhao, Yongxiang; Schubert, Heidi; Blakely, Alan; Forbush, Biff; Smith, Micholas Dean; Rinehart, Jesse; Cao, Erhu |
Nature communications |
39143061 |
2024 Aug 14 |
Structures, functions and adaptations of the human LINE-1 ORF2 protein. |
Baldwin, Eric T; van Eeuwen, Trevor; Hoyos, David; Zalevsky, Arthur; Tchesnokov, Egor P; Sánchez, Roberto; Miller, Bryant D; Di Stefano, Luciano H; Ruiz, Francesc Xavier; Hancock, Matthew; Işik, Esin; Mendez-Dorantes, Carlos; Walpole, Thomas; Nichols, Charles; Wan, Paul; Riento, Kirsi; Halls-Kass, Rowan; Augustin, Martin; Lammens, Alfred; Jestel, Anja; Upla, Paula; Xibinaku, Kera; Congreve, Samantha; Hennink, Maximiliaan; Rogala, Kacper B; Schneider, Anna M; Fairman, Jennifer E; Christensen, Shawn M; Desrosiers, Brian; Bisacchi, Gregory S; Saunders, Oliver L; Hafeez, Nafeeza; Miao, Wenyan; Kapeller, Rosana; Zaller, Dennis M; Sali, Andrej; Weichenrieder, Oliver; Burns, Kathleen H; Götte, Matthias; Rout, Michael P; Arnold, Eddy; Greenbaum, Benjamin D; Romero, Donna L; LaCava, John; Taylor, Martin S |
Nature |
38096902 |
2024 Feb |
B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. |
Wu, Cheng-Guo; Balakrishnan, Vijaya K; Merrill, Ronald A; Parihar, Pankaj S; Konovolov, Kirill; Chen, Yu-Chia; Xu, Zhen; Wei, Hui; Sundaresan, Ramya; Cui, Qiang; Wadzinski, Brian E; Swingle, Mark R; Musiyenko, Alla; Chung, Wendy K; Honkanen, Richard E; Suzuki, Aussie; Huang, Xuhui; Strack, Stefan; Xing, Yongna |
Proceedings of the National Academy of Sciences of the United States of America |
38150499 |
2024 Jan 02 |
The mating pilus of E. coli pED208 acts as a conduit for ssDNA during horizontal gene transfer. |
Beltrán, Leticia; Torsilieri, Holly; Patkowski, Jonasz B; Yang, Jie E; Casanova, James; Costa, Tiago R D; Wright, Elizabeth R; Egelman, Edward H |
mBio |
38051116 |
2024 Jan 16 |
Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. |
Padi, Sathish K R; Vos, Margaret R; Godek, Rachel J; Fuller, James R; Kruse, Thomas; Hein, Jamin B; Nilsson, Jakob; Kelker, Matthew S; Page, Rebecca; Peti, Wolfgang |
Nature |
38123684 |
2024 Jan |
Molecular basis of human trace amine-associated receptor 1 activation. |
Zilberg, Gregory; Parpounas, Alexandra K; Warren, Audrey L; Yang, Shifan; Wacker, Daniel |
Nature communications |
38168118 |
2024 Jan 02 |
Cryo-EM structure and molecular dynamic simulations explain the enhanced stability and ATP activity of the pathological chaperonin mutant. |
Syed, Aiza; Zhai, Jihang; Guo, Baolin; Zhao, Yuan; Wang, Joseph Che-Yen; Chen, Lingling |
Structure (London, England : 1993) |
38412855 |
2024 May 02 |
Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. |
Nadezhdin, Kirill D; Correia, Leonor; Shalygin, Alexey; Aktolun, Muhammed; Neuberger, Arthur; Gudermann, Thomas; Kurnikova, Maria G; Chubanov, Vladimir; Sobolevsky, Alexander I |
Cell reports |
38615321 |
2024 Apr 23 |
Molecular basis of proton-sensing by G protein-coupled receptors. |
Howard, Matthew K; Hoppe, Nicholas; Huang, Xi-Ping; Macdonald, Christian B; Mehrota, Eshan; Grimes, Patrick Rockefeller; Zahm, Adam; Trinidad, Donovan D; English, Justin; Coyote-Maestas, Willow; Manglik, Aashish |
bioRxiv : the preprint server for biology |
38659943 |
2024 Apr 18 |
Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2. |
Hu, Wenxin; Song, Alex; Zheng, Hongjin |
Nature communications |
38684689 |
2024 Apr 29 |
Functional and structural basis of human parainfluenza virus type 3 neutralization with human monoclonal antibodies. |
Suryadevara, Naveenchandra; Otrelo-Cardoso, Ana Rita; Kose, Nurgun; Hu, Yao-Xiong; Binshtein, Elad; Wolters, Rachael M; Greninger, Alexander L; Handal, Laura S; Carnahan, Robert H; Moscona, Anne; Jardetzky, Theodore S; Crowe Jr, James E |
Nature microbiology |
38858594 |
2024 Aug |
A stargate mechanism of Microviridae genome delivery unveiled by cryogenic electron tomography. |
Bardy, Pavol; MacDonald, Conor I W; Kirchberger, Paul C; Jenkins, Huw T; Botka, Tibor; Byrom, Lewis; Alim, Nawshin T B; Traore, Daouda A K; König, Hannah C; Nicholas, Tristan R; Chechik, Maria; Hart, Samuel J; Turkenburg, Johan P; Blaza, James N; Beatty, J Thomas; Fogg, Paul C M; Antson, Alfred A |
bioRxiv : the preprint server for biology |
38915634 |
2024 Jun 11 |
Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy. |
Schnicker, Nicholas J; Xu, Zhen; Amir, Mohammad; Gakhar, Lokesh; Huang, Chou-Long |
bioRxiv : the preprint server for biology |
38496408 |
2024 Mar 06 |
ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity. |
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bioRxiv : the preprint server for biology |
33758867 |
2021 Mar 14 |
Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation. |
Jette, Claudia A; Barnes, Christopher O; Kirk, Sharon M; Melillo, Bruno; Smith 3rd, Amos B; Bjorkman, Pamela J |
Nature communications |
33782388 |
2021 03 29 |
Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. |
Cerutti, Gabriele; Guo, Yicheng; Zhou, Tongqing; Gorman, Jason; Lee, Myungjin; Rapp, Micah; Reddem, Eswar R; Yu, Jian; Bahna, Fabiana; Bimela, Jude; Huang, Yaoxing; Katsamba, Phinikoula S; Liu, Lihong; Nair, Manoj S; Rawi, Reda; Olia, Adam S; Wang, Pengfei; Zhang, Baoshan; Chuang, Gwo-Yu; Ho, David D; Sheng, Zizhang; Kwong, Peter D; Shapiro, Lawrence |
Cell host & microbe |
33789084 |
2021 05 12 |
Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class. |
Rapp, Micah; Guo, Yicheng; Reddem, Eswar R; Yu, Jian; Liu, Lihong; Wang, Pengfei; Cerutti, Gabriele; Katsamba, Phinikoula; Bimela, Jude S; Bahna, Fabiana A; Mannepalli, Seetha M; Zhang, Baoshan; Kwong, Peter D; Huang, Yaoxing; Ho, David D; Shapiro, Lawrence; Sheng, Zizhang |
Cell reports |
33794145 |
2021 04 06 |
Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM. |
Shen, Betty W; Quispe, Joel D; Luyten, Yvette; McGough, Benjamin E; Morgan, Richard D; Stoddard, Barry L |
Structure (London, England : 1993) |
33826880 |
2021 Jun 03 |
Extracellular cap domain is an essential component of the TRPV1 gating mechanism. |
Nadezhdin, Kirill D; Neuberger, Arthur; Nikolaev, Yury A; Murphy, Lyle A; Gracheva, Elena O; Bagriantsev, Sviatoslav N; Sobolevsky, Alexander I |
Nature communications |
33846324 |
2021 04 12 |
Structural basis of long-range to short-range synaptic transition in NHEJ. |
Chen, Siyu; Lee, Linda; Naila, Tasmin; Fishbain, Susan; Wang, Annie; Tomkinson, Alan E; Lees-Miller, Susan P; He, Yuan |
Nature |
33854234 |
2021 May |
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. |
Malone, Brandon; Chen, James; Wang, Qi; Llewellyn, Eliza; Choi, Young Joo; Olinares, Paul Dominic B; Cao, Xinyun; Hernandez, Carolina; Eng, Edward T; Chait, Brian T; Shaw, David E; Landick, Robert; Darst, Seth A; Campbell, Elizabeth A |
Proceedings of the National Academy of Sciences of the United States of America |
33883267 |
2021 05 11 |
Cryo-EM structure of a thermostable bacterial nanocompartment. |
Wiryaman, Timothy; Toor, Navtej |
IUCrJ |
33953921 |
2021 May 01 |
Structures of telomerase at several steps of telomere repeat synthesis. |
He, Yao; Wang, Yaqiang; Liu, Baocheng; Helmling, Christina; Sušac, Lukas; Cheng, Ryan; Zhou, Z Hong; Feigon, Juli |
Nature |
33981033 |
2021 05 |
Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. |
Yu, Jie; Rao, Prashant; Clark, Sarah; Mitra, Jaba; Ha, Taekjip; Gouaux, Eric |
Nature |
33981040 |
2021 Jun |
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. |
Williams, Wilton B; Meyerhoff, R Ryan; Edwards, R J; Li, Hui; Manne, Kartik; Nicely, Nathan I; Henderson, Rory; Zhou, Ye; Janowska, Katarzyna; Mansouri, Katayoun; Gobeil, Sophie; Evangelous, Tyler; Hora, Bhavna; Berry, Madison; Abuahmad, A Yousef; Sprenz, Jordan; Deyton, Margaret; Stalls, Victoria; Kopp, Megan; Hsu, Allen L; Borgnia, Mario J; Stewart-Jones, Guillaume B E; Lee, Matthew S; Bronkema, Naomi; Moody, M Anthony; Wiehe, Kevin; Bradley, Todd; Alam, S Munir; Parks, Robert J; Foulger, Andrew; Oguin, Thomas; Sempowski, Gregory D; Bonsignori, Mattia; LaBranche, Celia C; Montefiori, David C; Seaman, Michael; Santra, Sampa; Perfect, John; Francica, Joseph R; Lynn, Geoffrey M; Aussedat, Baptiste; Walkowicz, William E; Laga, Richard; Kelsoe, Garnett; Saunders, Kevin O; Fera, Daniela; Kwong, Peter D; Seder, Robert A; Bartesaghi, Alberto; Shaw, George M; Acharya, Priyamvada; Haynes, Barton F |
Cell |
34019795 |
2021 05 27 |
Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment. |
Sharif, Humayun; Hollingsworth, L Robert; Griswold, Andrew R; Hsiao, Jeffrey C; Wang, Qinghui; Bachovchin, Daniel A; Wu, Hao |
Immunity |
34019797 |
2021 07 13 |
TRPV3 expression and purification for structure determination by Cryo-EM. |
Neuberger, Arthur; Nadezhdin, Kirill D; Sobolevsky, Alexander I |
Methods in enzymology |
34059288 |
2021 |
Structure and function at the lipid-protein interface of a pentameric ligand-gated ion channel. |
Kumar, Pramod; Cymes, Gisela D; Grosman, Claudio |
Proceedings of the National Academy of Sciences of the United States of America |
34083441 |
2021 06 08 |
Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy. |
Driggers, Camden M; Shyng, Show-Ling |
Methods in enzymology |
34099169 |
2021 |
Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair. |
van Eeuwen, Trevor; Shim, Yoonjung; Kim, Hee Jong; Zhao, Tingting; Basu, Shrabani; Garcia, Benjamin A; Kaplan, Craig D; Min, Jung-Hyun; Murakami, Kenji |
Nature communications |
34099686 |
2021 06 07 |
Structural insight on assembly-line catalysis in terpene biosynthesis. |
Faylo, Jacque L; van Eeuwen, Trevor; Kim, Hee Jong; Gorbea Colón, Jose J; Garcia, Benjamin A; Murakami, Kenji; Christianson, David W |
Nature communications |
34108468 |
2021 06 09 |
Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies. |
Cerutti, Gabriele; Rapp, Micah; Guo, Yicheng; Bahna, Fabiana; Bimela, Jude; Reddem, Eswar R; Yu, Jian; Wang, Pengfei; Liu, Lihong; Huang, Yaoxing; Ho, David D; Kwong, Peter D; Sheng, Zizhang; Shapiro, Lawrence |
Structure (London, England : 1993) |
34111408 |
2021 07 01 |
Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection. |
Chen, Peng; Zeng, Ji; Liu, Zheng; Thaker, Hatim; Wang, Siyu; Tian, Songhai; Zhang, Jie; Tao, Liang; Gutierrez, Craig B; Xing, Li; Gerhard, Ralf; Huang, Lan; Dong, Min; Jin, Rongsheng |
Nature communications |
34145250 |
2021 06 18 |
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. |
Gobeil, Sophie M-C; Janowska, Katarzyna; McDowell, Shana; Mansouri, Katayoun; Parks, Robert; Stalls, Victoria; Kopp, Megan F; Manne, Kartik; Li, Dapeng; Wiehe, Kevin; Saunders, Kevin O; Edwards, Robert J; Korber, Bette; Haynes, Barton F; Henderson, Rory; Acharya, Priyamvada |
Science (New York, N.Y.) |
34168071 |
2021 08 06 |
Heat-dependent opening of TRPV1 in the presence of capsaicin. |
Kwon, Do Hoon; Zhang, Feng; Suo, Yang; Bouvette, Jonathan; Borgnia, Mario J; Lee, Seok-Yong |
Nature structural & molecular biology |
34239123 |
2021 07 |
Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. |
Nadezhdin, Kirill D; Neuberger, Arthur; Trofimov, Yuri A; Krylov, Nikolay A; Sinica, Viktor; Kupko, Nikita; Vlachova, Viktorie; Zakharian, Eleonora; Efremov, Roman G; Sobolevsky, Alexander I |
Nature structural & molecular biology |
34239124 |
2021 07 |
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. |
Li, Dapeng; Edwards, Robert J; Manne, Kartik; Martinez, David R; Schäfer, Alexandra; Alam, S Munir; Wiehe, Kevin; Lu, Xiaozhi; Parks, Robert; Sutherland, Laura L; Oguin 3rd, Thomas H; McDanal, Charlene; Perez, Lautaro G; Mansouri, Katayoun; Gobeil, Sophie M C; Janowska, Katarzyna; Stalls, Victoria; Kopp, Megan; Cai, Fangping; Lee, Esther; Foulger, Andrew; Hernandez, Giovanna E; Sanzone, Aja; Tilahun, Kedamawit; Jiang, Chuancang; Tse, Longping V; Bock, Kevin W; Minai, Mahnaz; Nagata, Bianca M; Cronin, Kenneth; Gee-Lai, Victoria; Deyton, Margaret; Barr, Maggie; Von Holle, Tarra; Macintyre, Andrew N; Stover, Erica; Feldman, Jared; Hauser, Blake M; Caradonna, Timothy M; Scobey, Trevor D; Rountree, Wes; Wang, Yunfei; Moody, M Anthony; Cain, Derek W; DeMarco, C Todd; Denny, Thomas N; Woods, Christopher W; Petzold, Elizabeth W; Schmidt, Aaron G; Teng, I-Ting; Zhou, Tongqing; Kwong, Peter D; Mascola, John R; Graham, Barney S; Moore, Ian N; Seder, Robert; Andersen, Hanne; Lewis, Mark G; Montefiori, David C; Sempowski, Gregory D; Baric, Ralph S; Acharya, Priyamvada; Haynes, Barton F; Saunders, Kevin O |
Cell |
34242577 |
2021 08 05 |
Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. |
Lopez-Redondo, Maria; Fan, Shujie; Koide, Akiko; Koide, Shohei; Beckstein, Oliver; Stokes, David L |
The Journal of general physiology |
34254979 |
2021 Aug 02 |
Structural basis for potassium transport in prokaryotes by KdpFABC. |
Sweet, Marie E; Larsen, Casper; Zhang, Xihui; Schlame, Michael; Pedersen, Bjørn P; Stokes, David L |
Proceedings of the National Academy of Sciences of the United States of America |
34272288 |
2021 Jul 20 |
Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60. |
Wang, Joseph Che-Yen; Chen, Lingling |
Scientific reports |
34285302 |
2021 07 20 |
Allosteric Inhibition of a Vesicular Glutamate Transporter by an Isoform-Specific Antibody. |
Eriksen, Jacob; Li, Fei; Stroud, Robert M; Edwards, Robert H |
Biochemistry |
34319067 |
2021 08 17 |
Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. |
Hu, Qi; Botuyan, Maria Victoria; Zhao, Debiao; Cui, Gaofeng; Mer, Elie; Mer, Georges |
Nature |
34321665 |
2021 08 |
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes. |
Sun, Dapeng; Sang, Zhe; Kim, Yong Joon; Xiang, Yufei; Cohen, Tomer; Belford, Anna K; Huet, Alexis; Conway, James F; Sun, Ji; Taylor, Derek J; Schneidman-Duhovny, Dina; Zhang, Cheng; Huang, Wei; Shi, Yi |
Nature communications |
34344900 |
2021 08 03 |
HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases. |
Rathinaswamy, Manoj K; Fleming, Kaelin D; Dalwadi, Udit; Pardon, Els; Harris, Noah J; Yip, Calvin K; Steyaert, Jan; Burke, John E |
Structure (London, England : 1993) |
34348129 |
2021 12 02 |
Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution. |
Su, Zhaoming; Zhang, Kaiming; Kappel, Kalli; Li, Shanshan; Palo, Michael Z; Pintilie, Grigore D; Rangan, Ramya; Luo, Bingnan; Wei, Yuquan; Das, Rhiju; Chiu, Wah |
Nature |
34381213 |
2021 Aug |
Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. |
Su, Chih-Chia; Klenotic, Philip A; Cui, Meng; Lyu, Meinan; Morgan, Christopher E; Yu, Edward W |
PLoS biology |
34383749 |
2021 Aug |
Structural and mechanistic basis for protein glutamylation by the kinase fold. |
Osinski, Adam; Black, Miles H; Pawłowski, Krzysztof; Chen, Zhe; Li, Yang; Tagliabracci, Vincent S |
Molecular cell |
34407442 |
2021 Aug 12 |
The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. |
Plenge, Per; Yang, Dongxue; Salomon, Kristine; Laursen, Louise; Kalenderoglou, Iris E; Newman, Amy H; Gouaux, Eric; Coleman, Jonathan A; Loland, Claus J |
Nature communications |
34417466 |
2021 08 20 |
Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. |
Zhang, Kaiming; Zheludev, Ivan N; Hagey, Rachel J; Haslecker, Raphael; Hou, Yixuan J; Kretsch, Rachael; Pintilie, Grigore D; Rangan, Ramya; Kladwang, Wipapat; Li, Shanshan; Wu, Marie Teng-Pei; Pham, Edward A; Bernardin-Souibgui, Claire; Baric, Ralph S; Sheahan, Timothy P; D'Souza, Victoria; Glenn, Jeffrey S; Chiu, Wah; Das, Rhiju |
Nature structural & molecular biology |
34426697 |
2021 09 |
Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation. |
Rathinaswamy, Manoj K; Dalwadi, Udit; Fleming, Kaelin D; Adams, Carson; Stariha, Jordan T B; Pardon, Els; Baek, Minkyung; Vadas, Oscar; DiMaio, Frank; Steyaert, Jan; Hansen, Scott D; Yip, Calvin K; Burke, John E |
Science advances |
34452907 |
2021 Aug |
A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants. |
Schmitz, Aaron J; Turner, Jackson S; Liu, Zhuoming; Zhou, Julian Q; Aziati, Ishmael D; Chen, Rita E; Joshi, Astha; Bricker, Traci L; Darling, Tamarand L; Adelsberg, Daniel C; Altomare, Clara G; Alsoussi, Wafaa B; Case, James Brett; VanBlargan, Laura A; Lei, Tingting; Thapa, Mahima; Amanat, Fatima; Jeevan, Trushar; Fabrizio, Thomas; O'Halloran, Jane A; Shi, Pei-Yong; Presti, Rachel M; Webby, Richard J; Krammer, Florian; Whelan, Sean P J; Bajic, Goran; Diamond, Michael S; Boon, Adrianus C M; Ellebedy, Ali H |
Immunity |
34464596 |
2021 09 14 |
Computational Methods for Single-Particle Electron Cryomicroscopy. |
Singer, Amit; Sigworth, Fred J |
Annual review of biomedical data science |
34485850 |
2020 07 |
Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. |
Novikova, Irina V; Zhou, Mowei; Du, Chen; Parra, Marcelina; Kim, Doo Nam; VanAernum, Zachary L; Shaw, Jared B; Hellmann, Hanjo; Wysocki, Vicki H; Evans, James E |
ACS chemical biology |
34520180 |
2021 11 19 |
AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. |
Caffrey, Brian; Zhu, Xing; Berezuk, Alison; Tuttle, Katharine; Chittori, Sagar; Subramaniam, Sriram |
The Journal of biological chemistry |
34520757 |
2021 10 |
Architecture and assembly mechanism of native glycine receptors. |
Zhu, Hongtao; Gouaux, Eric |
Nature |
34555840 |
2021 11 |
Micropatterning Transmission Electron Microscopy Grids to Direct Cell Positioning within Whole-Cell Cryo-Electron Tomography Workflows. |
Sibert, Bryan S; Kim, Joseph Y; Yang, Jie E; Wright, Elizabeth R |
Journal of visualized experiments : JoVE |
34570100 |
2021 09 13 |
Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. |
Scortecci, Jessica Fernandes; Molday, Laurie L; Curtis, Susan B; Garces, Fabian A; Panwar, Pankaj; Van Petegem, Filip; Molday, Robert S |
Nature communications |
34625547 |
2021 10 08 |
Structural basis of chromatin regulation by histone variant H2A.Z. |
Lewis, Tyler S; Sokolova, Vladyslava; Jung, Harry; Ng, Honkit; Tan, Dongyan |
Nucleic acids research |
34643712 |
2021 Nov 08 |
Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses. |
Feldman, Jared; Bals, Julia; Altomare, Clara G; St Denis, Kerri; Lam, Evan C; Hauser, Blake M; Ronsard, Larance; Sangesland, Maya; Moreno, Thalia Bracamonte; Okonkwo, Vintus; Hartojo, Nathania; Balazs, Alejandro B; Bajic, Goran; Lingwood, Daniel; Schmidt, Aaron G |
Science immunology |
34648356 |
2021 12 10 |
Structure and desensitization of AMPA receptor complexes with type II TARP γ5 and GSG1L. |
Klykov, Oleg; Gangwar, Shanti Pal; Yelshanskaya, Maria V; Yen, Laura; Sobolevsky, Alexander I |
Molecular cell |
34678168 |
2021 12 02 |
Electron crystallography of chiral and non-chiral small molecules. |
Zhou, Weijiang; Bammes, Benjamin; Mitchell, Patrick G; Betz, Kerry; Chiu, Wah |
Ultramicroscopy |
34695647 |
2021 Oct 19 |
Vascular KATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. |
Sung, Min Woo; Yang, Zhongying; Driggers, Camden M; Patton, Bruce L; Mostofian, Barmak; Russo, John D; Zuckerman, Daniel M; Shyng, Show-Ling |
Proceedings of the National Academy of Sciences of the United States of America |
34711681 |
2021 11 02 |
Selective G protein signaling driven by substance P-neurokinin receptor dynamics. |
Harris, Julian A; Faust, Bryan; Gondin, Arisbel B; Dämgen, Marc André; Suomivuori, Carl-Mikael; Veldhuis, Nicholas A; Cheng, Yifan; Dror, Ron O; Thal, David M; Manglik, Aashish |
Nature chemical biology |
34711980 |
2021 Oct 28 |
Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole. |
Neuberger, Arthur; Nadezhdin, Kirill D; Sobolevsky, Alexander I |
Nature communications |
34725357 |
2021 11 01 |
Mapping the catalytic conformations of an assembly-line polyketide synthase module. |
Cogan, Dillon P; Zhang, Kaiming; Li, Xiuyuan; Li, Shanshan; Pintilie, Grigore D; Roh, Soung-Hun; Craik, Charles S; Chiu, Wah; Khosla, Chaitan |
Science (New York, N.Y.) |
34735239 |
2021 11 05 |
A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure. |
Bonilla, Steve L; Sherlock, Madeline E; MacFadden, Andrea; Kieft, Jeffrey S |
Science (New York, N.Y.) |
34793227 |
2021 11 19 |
Broadening access to cryoEM through centralized facilities. |
Zimanyi, Christina M; Kopylov, Mykhailo; Potter, Clinton S; Carragher, Bridget; Eng, Edward T |
Trends in biochemical sciences |
34823974 |
2022 Feb |
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. |
Chen, Kai-En; Guo, Qian; Hill, Timothy A; Cui, Yi; Kendall, Amy K; Yang, Zhe; Hall, Ryan J; Healy, Michael D; Sacharz, Joanna; Norwood, Suzanne J; Fonseka, Sachini; Xie, Boyang; Reid, Robert C; Leneva, Natalya; Parton, Robert G; Ghai, Rajesh; Stroud, David A; Fairlie, David P; Suga, Hiroaki; Jackson, Lauren P; Teasdale, Rohan D; Passioura, Toby; Collins, Brett M |
Science advances |
34851660 |
2021 Dec 03 |
Illumination of serotonin transporter mechanism and role of the allosteric site. |
Yang, Dongxue; Gouaux, Eric |
Science advances |
34851672 |
2021 Dec 03 |
NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. |
Andreeva, Liudmila; David, Liron; Rawson, Shaun; Shen, Chen; Pasricha, Teerithveen; Pelegrin, Pablo; Wu, Hao |
Cell |
34861190 |
2021 12 22 |
Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer. |
Hu, Wenxin; Zheng, Hongjin |
Communications biology |
34887516 |
2021 12 09 |
Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter. |
Thaker, Tarjani M; Mishra, Smriti; Zhou, Wenchang; Mohan, Michael; Tang, Qingyu; Faraldo-Goméz, José D; Mchaourab, Hassane S; Tomasiak, Thomas M |
Nature chemical biology |
34931066 |
2022 02 |
Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography. |
Elferich, Johannes; Clark, Sarah; Ge, Jingpeng; Goehring, April; Matsui, Aya; Gouaux, Eric |
eLife |
34964715 |
2021 12 29 |
Structure of the human cone photoreceptor cyclic nucleotide-gated channel. |
Zheng, Xiangdong; Hu, Zhengshan; Li, Huan; Yang, Jian |
Nature structural & molecular biology |
34969976 |
2022 Jan |
Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. |
Yang, Chun; Fujiwara, Rina; Kim, Hee Jong; Basnet, Pratik; Zhu, Yunye; Gorbea Colón, Jose J; Steimle, Stefan; Garcia, Benjamin A; Kaplan, Craig D; Murakami, Kenji |
Molecular cell |
35051353 |
2022 02 03 |
Label-free visual proteomics: Coupling MS- and EM-based approaches in structural biology. |
Klykov, Oleg; Kopylov, Mykhailo; Carragher, Bridget; Heck, Albert J R; Noble, Alex J; Scheltema, Richard A |
Molecular cell |
35063097 |
2022 01 20 |
An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. |
Morgan, Christopher E; Zhang, Zhemin; Bonomo, Robert A; Yu, Edward W |
mBio |
35100868 |
2022 Feb 01 |
A Robust Single-Particle Cryo-Electron Microscopy (cryo-EM) Processing Workflow with cryoSPARC, RELION, and Scipion. |
DiIorio, Megan C; Kulczyk, Arkadiusz W |
Journal of visualized experiments : JoVE |
35104261 |
2022 01 31 |
Gating choreography and mechanism of the human proton-activated chloride channel ASOR. |
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Science advances |
35108041 |
2022 Feb 04 |
Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P2 and rapamycin. |
Gan, Ninghai; Han, Yan; Zeng, Weizhong; Wang, Yan; Xue, Jing; Jiang, Youxing |
Proceedings of the National Academy of Sciences of the United States of America |
35131932 |
2022 Feb 15 |
Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. |
Tsai, Kaitlyn; Stojković, Vanja; Lee, D John; Young, Iris D; Szal, Teresa; Klepacki, Dorota; Vázquez-Laslop, Nora; Mankin, Alexander S; Fraser, James S; Fujimori, Danica Galonić |
Nature structural & molecular biology |
35165456 |
2022 02 |
Development of an atmospheric plasma jet device for versatile treatment of electron microscope sample grids. |
Ahn, Eungjin; Tang, Tianyu; Kim, Byungchul; Lee, Hae June; Cho, Uhn-Soo |
The Journal of biological chemistry |
35248533 |
2022 Apr |
Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. |
Chen, James; Wang, Qi; Malone, Brandon; Llewellyn, Eliza; Pechersky, Yakov; Maruthi, Kashyap; Eng, Ed T; Perry, Jason K; Campbell, Elizabeth A; Shaw, David E; Darst, Seth A |
Nature structural & molecular biology |
35260847 |
2022 03 |
The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation. |
Khandelwal, Nitesh Kumar; Millan, Cinthia R; Zangari, Samantha I; Avila, Samantha; Williams, Dewight; Thaker, Tarjani M; Tomasiak, Thomas M |
Nature communications |
35277487 |
2022 Mar 11 |
Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. |
Kafai, Natasha M; Williamson, Lauren E; Binshtein, Elad; Sukupolvi-Petty, Soila; Gardner, Christina L; Liu, Jaclyn; Mackin, Samantha; Kim, Arthur S; Kose, Nurgun; Carnahan, Robert H; Jung, Ana; Droit, Lindsay; Reed, Douglas S; Handley, Scott A; Klimstra, William B; Crowe, James E; Diamond, Michael S |
The Journal of experimental medicine |
35297953 |
2022 04 04 |
Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer. |
Koo, Christopher W; Tucci, Frank J; He, Yuan; Rosenzweig, Amy C |
Science (New York, N.Y.) |
35298269 |
2022 03 18 |
Structural mechanism of muscle nicotinic receptor desensitization and block by curare. |
Rahman, Md Mahfuzur; Basta, Tamara; Teng, Jinfeng; Lee, Myeongseon; Worrell, Brady T; Stowell, Michael H B; Hibbs, Ryan E |
Nature structural & molecular biology |
35301478 |
2022 04 |
Better, Faster, Cheaper: Recent Advances in Cryo-Electron Microscopy. |
Chua, Eugene Y D; Mendez, Joshua H; Rapp, Micah; Ilca, Serban L; Tan, Yong Zi; Maruthi, Kashyap; Kuang, Huihui; Zimanyi, Christina M; Cheng, Anchi; Eng, Edward T; Noble, Alex J; Potter, Clinton S; Carragher, Bridget |
Annual review of biochemistry |
35320683 |
2022 Jun 21 |
50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA. |
Laughlin, Zane T; Nandi, Suparno; Dey, Debayan; Zelinskaya, Natalia; Witek, Marta A; Srinivas, Pooja; Nguyen, Ha An; Kuiper, Emily G; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L |
Proceedings of the National Academy of Sciences of the United States of America |
35357969 |
2022 Apr 05 |
Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation. |
Abskharon, Romany; Sawaya, Michael R; Boyer, David R; Cao, Qin; Nguyen, Binh A; Cascio, Duilio; Eisenberg, David S |
Proceedings of the National Academy of Sciences of the United States of America |
35377792 |
2022 04 12 |
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2022 04 05 |
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Nature communications |
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2022 04 06 |
Cryo-EM structure of the prothrombin-prothrombinase complex. |
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2022 06 02 |
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2022 05 12 |
Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide. |
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2022 05 18 |
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2022 05 24 |
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2022 06 07 |
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2022 08 05 |
Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold. |
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Science (New York, N.Y.) |
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2022 06 10 |
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Science (New York, N.Y.) |
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2022 06 10 |
Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody. |
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2022 Jun 17 |
Structures of an active type III-A CRISPR effector complex. |
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Structure (London, England : 1993) |
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2022 Aug 04 |
Superimmunity by pan-sarbecovirus nanobodies. |
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Cell reports |
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2022 Jun 28 |
Structure of the human cation-chloride cotransport KCC1 in an outward-open state. |
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Proceedings of the National Academy of Sciences of the United States of America |
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2022 Jul 05 |
Development of CryoVR, a virtual reality training system for hands-on cryoEM operations. |
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Acta crystallographica. Section D, Structural biology |
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2022 Jul 01 |
Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. |
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Nature structural & molecular biology |
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2022 Jul |
Architecture of the human erythrocyte ankyrin-1 complex. |
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Nature structural & molecular biology |
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2022 07 |
Three-dimensional structure-guided evolution of a ribosome with tethered subunits. |
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Nature chemical biology |
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2022 Jul 14 |
Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3. |
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Nature structural & molecular biology |
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2022 08 |
Conformational landscape of the yeast SAGA complex as revealed by cryo-EM. |
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Scientific reports |
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2022 07 19 |
Structures of the nitrogenase complex prepared under catalytic turnover conditions. |
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Science (New York, N.Y.) |
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2022 08 19 |
Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. |
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The Journal of biological chemistry |
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2022 Sep |
Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities. |
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Nature communications |
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2022 08 06 |
Autoantibody mimicry of hormone action at the thyrotropin receptor. |
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Nature |
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2022 09 |
Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery. |
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Nature communications |
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2022 08 15 |
Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA. |
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Science advances |
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2022 Aug 26 |
Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. |
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Nature communications |
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2022 08 31 |
The promise of cryo-EM to explore RNA structural dynamics. |
Bonilla, Steve L; Kieft, Jeffrey S |
Journal of molecular biology |
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2022 Sep 30 |
Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. |
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Proceedings of the National Academy of Sciences of the United States of America |
36067294 |
2022 Sep 13 |
Methotrexate recognition by the human reduced folate carrier SLC19A1. |
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Nature |
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2022 09 |
Structural basis for APE1 processing DNA damage in the nucleosome. |
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Nature communications |
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2022 09 14 |
Improved mammalian retromer cryo-EM structures reveal a new assembly interface. |
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The Journal of biological chemistry |
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2022 Sep 26 |
Metallic support films reduce optical heating in cryogenic correlative light and electron tomography. |
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Journal of structural biology |
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2022 Oct 01 |
Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria. |
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Nature communications |
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2022 Oct 03 |
Cryo-EM structure-based selection of computed ligand poses enables design of MTA-synergic PRMT5 inhibitors of better potency. |
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Communications biology |
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2022 10 03 |
Structures of the TMC-1 complex illuminate mechanosensory transduction. |
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Nature |
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2022 10 |
Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage. |
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Frontiers in immunology |
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2022 Nov 01 |
Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP2. |
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Science (New York, N.Y.) |
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2022 10 14 |
Structural principles of B cell antigen receptor assembly. |
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Nature |
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2022 Dec |
PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. |
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Molecular cell |
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2022 Nov 17 |
Structures of the holo CRISPR RNA-guided transposon integration complex. |
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Nature |
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2023 Jan |
Molecular architecture of the Chikungunya virus replication complex. |
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Science advances |
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2022 Dec 02 |
Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. |
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The Journal of general physiology |
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2023 Feb 06 |
Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. |
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Nature structural & molecular biology |
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2022 Dec |
Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction. |
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The Journal of biological chemistry |
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2023 Jan |
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. |
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bioRxiv : the preprint server for biology |
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2022 Dec 26 |
Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. |
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2023 Jan |
Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5. |
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Nature structural & molecular biology |
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2023 Feb |
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Bio-protocol |
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2022 Nov 05 |
Inhibition of the proton-activated chloride channel PAC by PIP2. |
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eLife |
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2023 Jan 12 |
Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. |
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The Journal of general physiology |
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2023 Mar 06 |
Mechanism of Ca2+ transport by ferroportin. |
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eLife |
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2023 Jan 17 |
Structural basis of ferroportin inhibition by minihepcidin PR73. |
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PLoS biology |
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2023 Jan |
A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. |
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2023 Mar 02 |
Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1. |
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Structure (London, England : 1993) |
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2023 Mar 02 |
Cryo-EM reveals the molecular basis oflaminin polymerization and LN-lamininopathies. |
Kulczyk, Arkadiusz W; McKee, Karen K; Zhang, Ximo; Bizukojc, Iwona; Yu, Ying Q; Yurchenco, Peter D |
Nature communications |
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2023 Jan 19 |
Nanovaccines Displaying the Influenza Virus Hemagglutinin in an Inverted Orientation Elicit an Enhanced Stalk-Directed Antibody Response. |
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2023 Jan 23 |
Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. |
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Proceedings of the National Academy of Sciences of the United States of America |
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2023 Jan 31 |
Structural basis of Rho-dependent transcription termination. |
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Nature |
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2023 Feb |
Structure of an endogenous mycobacterial MCE lipid transporter. |
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2023 Jan 10 |
Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM. |
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Nucleic acids research |
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2023 Feb 28 |
Structural basis for substrate selection by the SARS-CoV-2 replicase. |
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Nature |
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2023 Feb |
Cryo-EM structure of adeno-associated virus 4 at 2.2 Å resolution. |
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Acta crystallographica. Section D, Structural biology |
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2023 Feb 01 |
Cross-protective antibodies against common endemic respiratory viruses. |
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Nature communications |
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2023 Feb 13 |
Lysate-to-grid: Rapid Isolation of Native Complexes from Budding Yeast for Cryo-EM Imaging. |
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Bio-protocol |
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2023 Jan 20 |
Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. |
Fan, Minrui; Zhang, Jianxiu; Lee, Chien-Ling; Zhang, Jinru; Feng, Liang |
Nature |
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2023 Feb |
Conformational switching and flexibility in cobalamin-dependent methionine synthase studied by small-angle X-ray scattering and cryo-electron microscopy. |
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bioRxiv : the preprint server for biology |
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2023 Feb 12 |
Cryo-EM Structure of a Human LECT2 Amyloid Fibril Reveals a Network of Polar Ladders at its Core. |
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bioRxiv : the preprint server for biology |
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2023 Feb 11 |
Filament formation drives catalysis by glutaminase enzymes important in cancer progression. |
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bioRxiv : the preprint server for biology |
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2023 Jul 26 |
Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. |
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Cell reports |
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2023 Feb 28 |
rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. |
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Nature communications |
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2023 Mar 02 |
Energy Coupling and Stoichiometry of Zn2+/H+ Antiport by the Cation Diffusion Facilitator YiiP. |
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bioRxiv : the preprint server for biology |
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2023 Jul 31 |
Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of Methylococcus capsulatus Soluble Methane Monooxygenase Hydroxylase. |
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ACS nano |
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2023 Mar 28 |
30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. |
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bioRxiv : the preprint server for biology |
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2023 Apr 30 |
Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions. |
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Molecular cell |
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2023 Apr 20 |
Control of transcription elongation and DNA repair by alarmone ppGpp. |
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Nature structural & molecular biology |
36997761 |
2023 May |
Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy. |
Logan, Grant J; Mietzsch, Mario; Khandekar, Neeta; D'Silva, Arlene; Anderson, Daniel; Mandwie, Mawj; Hsi, Jane; Nelson, Austin R; Chipman, Paul; Jackson, Jennifer; Schofield, Peter; Christ, Daniel; Goodnow, Christopher C; Reed, Joanne H; Farrar, Michelle A; McKenna, Robert; Alexander, Ian E |
Molecular therapy : the journal of the American Society of Gene Therapy |
37012705 |
2023 Jul 05 |
Sensory specializations drive octopus and squid behaviour. |
Kang, Guipeun; Allard, Corey A H; Valencia-Montoya, Wendy A; van Giesen, Lena; Kim, Jeong Joo; Kilian, Peter B; Bai, Xiaochen; Bellono, Nicholas W; Hibbs, Ryan E |
Nature |
37045917 |
2023 Apr |
Structural basis of sensory receptor evolution in octopus. |
Allard, Corey A H; Kang, Guipeun; Kim, Jeong Joo; Valencia-Montoya, Wendy A; Hibbs, Ryan E; Bellono, Nicholas W |
Nature |
37045920 |
2023 Apr |
A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates. |
Weidenbacher, Payton A-B; Sanyal, Mrinmoy; Friedland, Natalia; Tang, Shaogeng; Arunachalam, Prabhu S; Hu, Mengyun; Kumru, Ozan S; Morris, Mary Kate; Fontenot, Jane; Shirreff, Lisa; Do, Jonathan; Cheng, Ya-Chen; Vasudevan, Gayathri; Feinberg, Mark B; Villinger, Francois J; Hanson, Carl; Joshi, Sangeeta B; Volkin, David B; Pulendran, Bali; Kim, Peter S |
Nature communications |
37069151 |
2023 Apr 17 |
Structure and mechanism of the alkane-oxidizing enzyme AlkB. |
Guo, Xue; Zhang, Jianxiu; Han, Lei; Lee, Juliet; Williams, Shoshana C; Forsberg, Allison; Xu, Yan; Austin, Rachel Narehood; Feng, Liang |
Nature communications |
37069165 |
2023 Apr 17 |
Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain. |
Harris, Noah J; Jenkins, Meredith L; Nam, Sung-Eun; Rathinaswamy, Manoj K; Parson, Matthew Ah; Ranga-Prasad, Harish; Dalwadi, Udit; Moeller, Brandon E; Sheekey, Eleanor; Hansen, Scott D; Yip, Calvin K; Burke, John E |
bioRxiv : the preprint server for biology |
37090531 |
2023 May 23 |
Human TRPV1 structure and inhibition by the analgesic SB-366791. |
Neuberger, Arthur; Oda, Mai; Nikolaev, Yury A; Nadezhdin, Kirill D; Gracheva, Elena O; Bagriantsev, Sviatoslav N; Sobolevsky, Alexander I |
Nature communications |
37117175 |
2023 Apr 28 |
Structure and assembly of a bacterial gasdermin pore. |
Johnson, Alex G; Mayer, Megan L; Schaefer, Stefan L; McNamara-Bordewick, Nora K; Hummer, Gerhard; Kranzusch, Philip J |
bioRxiv : the preprint server for biology |
37131678 |
2023 Oct 26 |
Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. |
Henderson, Rory; Zhou, Ye; Stalls, Victoria; Wiehe, Kevin; Saunders, Kevin O; Wagh, Kshitij; Anasti, Kara; Barr, Maggie; Parks, Robert; Alam, S Munir; Korber, Bette; Haynes, Barton F; Bartesaghi, Alberto; Acharya, Priyamvada |
Nature communications |
37188681 |
2023 May 15 |
Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor. |
Childers, Kenneth C; Avery, Nathan G; Estrada Alamo, Kevin A; Davulcu, Omar; Haynes, Rose Marie; Lollar, Pete; Doering, Christopher B; Coxon, Carmen H; Spiegel, P Clint |
Blood |
37192299 |
2023 Jul 13 |
EMC chaperone-CaV structure reveals an ion channel assembly intermediate. |
Chen, Zhou; Mondal, Abhisek; Abderemane-Ali, Fayal; Jang, Seil; Niranjan, Sangeeta; Montaño, José L; Zaro, Balyn W; Minor Jr, Daniel L |
Nature |
37196677 |
2023 Jul |
Polγ coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity. |
Park, Joon; Herrmann, Geoffrey K; Mitchell, Patrick G; Sherman, Michael B; Yin, Y Whitney |
Nature structural & molecular biology |
37202477 |
2023 Jun |
Video Captioning Using Global-Local Representation. |
Yan, Liqi; Ma, Siqi; Wang, Qifan; Chen, Yingjie; Zhang, Xiangyu; Savakis, Andreas; Liu, Dongfang |
IEEE transactions on circuits and systems for video technology : a publication of the Circuits and Systems Society |
37215187 |
2022 Oct |
Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex. |
Patel, Avinash B; Qing, Jinkang; Tam, Kelly H; Zaman, Sara; Luiso, Maria; Radhakrishnan, Ishwar; He, Yuan |
Nature communications |
37244892 |
2023 May 27 |
Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ. |
Chen, Siyu; Vogt, Alex; Lee, Linda; Naila, Tasmin; McKeown, Ryan; Tomkinson, Alan E; Lees-Miller, Susan P; He, Yuan |
Science advances |
37256947 |
2023 Jun 02 |
Structural interplay of anesthetics and paralytics on muscle nicotinic receptors. |
Goswami, Umang; Rahman, Md Mahfuzur; Teng, Jinfeng; Hibbs, Ryan E |
Nature communications |
37264005 |
2023 Jun 01 |
The role of CenKR in the coordination of Rhodobacter sphaeroides cell elongation and division. |
Lakey, Bryan D; Alberge, François; Parrell, Daniel; Wright, Elizabeth R; Noguera, Daniel R; Donohue, Timothy J |
mBio |
37283520 |
2023 Jun 07 |
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. |
Hoppe, Nicholas; Harrison, Simone; Hwang, Sun-Hee; Chen, Ziwei; Karelina, Masha; Deshpande, Ishan; Suomivuori, Carl-Mikael; Palicharla, Vivek R; Berry, Samuel P; Tschaikner, Philipp; Regele, Dominik; Covey, Douglas F; Stefan, Eduard; Marks, Debora S; Reit |
bioRxiv : the preprint server for biology |
37292845 |
2023 May 24 |
Structural basis of TFIIIC-dependent RNA Polymerase III transcription initiation. |
Talyzina, Anna; Han, Yan; Banerjee, Chiranjib; Fishbain, Susan; Reyes, Alexis; Vafabakhsh, Reza; He, Yuan |
bioRxiv : the preprint server for biology |
37292922 |
2023 May 16 |
ManiLoco: A VR-Based Locomotion Method for Concurrent Object Manipulation. |
Wan, Dayu; Guo, Xiaolei; Dong, Jiahui; Mousas, Christos; Chen, Yingjie |
Proceedings of the ACM on computer graphics and interactive techniques |
37293199 |
2023 May |
30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. |
Srinivas, Pooja; Nosrati, Meisam; Zelinskaya, Natalia; Dey, Debayan; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L |
Proceedings of the National Academy of Sciences of the United States of America |
37307464 |
2023 Jun 20 |
Virion glycosylation influences mycobacteriophage immune recognition. |
Freeman, Krista G; Robotham, Anna C; Parks, Olivia B; Abad, Lawrence; Jacobs-Sera, Deborah; Lauer, Michael J; Podgorski, Jennifer M; Zhang, Yu; Williams, John V; White, Simon J; Kelly, John F; Hatfull, Graham F; Pope, Welkin H |
Cell host & microbe |
37329881 |
2023 Jul 12 |
Conformational switching and flexibility in cobalamin-dependent methionine synthase studied by small-angle X-ray scattering and cryoelectron microscopy. |
Watkins, Maxwell B; Wang, Haoyue; Burnim, Audrey; Ando, Nozomi |
Proceedings of the National Academy of Sciences of the United States of America |
37339208 |
2023 Jun 27 |
The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems. |
Paraan, Mohammadreza; Nasef, Mohamed; Chou-Zheng, Lucy; Khweis, Sarah A; Schoeffler, Allyn J; Hatoum-Aslan, Asma; Stagg, Scott M; Dunkle, Jack A |
PloS one |
37352230 |
2023 |
Structure of human TRPV4 in complex with GTPase RhoA. |
Nadezhdin, Kirill D; Talyzina, Irina A; Parthasarathy, Aravind; Neuberger, Arthur; Zhang, David X; Sobolevsky, Alexander I |
Nature communications |
37353478 |
2023 Jun 23 |
TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. |
Kwon, Do Hoon; Zhang, Feng; McCray, Brett A; Feng, Shasha; Kumar, Meha; Sullivan, Jeremy M; Im, Wonpil; Sumner, Charlotte J; Lee, Seok-Yong |
Nature communications |
37353484 |
2023 Jun 23 |
Challenges in making ideal cryo-EM samples. |
Han, Bong-Gyoon; Avila-Sakar, Agustin; Remis, Jonathan; Glaeser, Robert M |
Current opinion in structural biology |
37392555 |
2023 Aug |
Structural basis for flagellin induced NAIP5 activation. |
Paidimuddala, Bhaskar; Cao, Jianhao; Zhang, Liman |
bioRxiv : the preprint server for biology |
37398004 |
2023 Jun 13 |
Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation. |
Talyzina, Anna; Han, Yan; Banerjee, Chiranjib; Fishbain, Susan; Reyes, Alexis; Vafabakhsh, Reza; He, Yuan |
Molecular cell |
37402369 |
2023 Jun 28 |
High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217. |
Li, Fenglin; Hou, Chun-Feng David; Lokareddy, Ravi K; Yang, Ruoyu; Forti, Francesca; Briani, Federica; Cingolani, Gino |
Nature communications |
37422479 |
2023 Jul 08 |
Focusing antibody responses to the fusion peptide in rhesus macaques. |
Cottrell, Christopher A; Pratap, Payal P; Cirelli, Kimberly M; Carnathan, Diane G; Enemuo, Chiamaka A; Antanasijevic, Aleksandar; Ozorowski, Gabriel; Sewall, Leigh M; Gao, Hongmei; Greene, Kelli M; Allen, Joel D; Ngo, Julia T; Choe, Yury; Nogal, Bartek; Silva, Murillo; Bhiman, Jinal; Pauthner, Matthias; Irvine, Darrell J; Montefiori, David; Crispin, Max; Burton, Dennis R; Silvestri, Guido; Crotty, Shane; Ward, Andrew B |
bioRxiv : the preprint server for biology |
37425865 |
2023 Jun 27 |
Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants. |
Yang, Dongxue; Zhao, Zhiyu; Tajkhorshid, Emad; Gouaux, Eric |
Proceedings of the National Academy of Sciences of the United States of America |
37436958 |
2023 Jul 18 |
Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. |
Jiou, Jenny; Shaffer, Joy M; Bernades, Natalia E; Fung, Ho Yee Joyce; Kikumoto Dias, Juliana; D'Arcy, Sheena; Chook, Yuh Min |
Proceedings of the National Academy of Sciences of the United States of America |
37450495 |
2023 Jul 18 |
Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. |
Hu, Zhengshan; Zheng, Xiangdong; Yang, Jian |
Nature communications |
37463923 |
2023 Jul 18 |
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry. |
Leonhardt, Susan A; Purdy, Michael D; Grover, Jonathan R; Yang, Ziwei; Poulos, Sandra; McIntire, William E; Tatham, Elizabeth A; Erramilli, Satchal K; Nosol, Kamil; Lai, Kin Kui; Ding, Shilei; Lu, Maolin; Uchil, Pradeep D; Finzi, Andrés; Rein, Alan; Kossiakoff, Anthony A; Mothes, Walther; Yeager, Mark |
Nature communications |
37474505 |
2023 Jul 20 |
Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. |
Li, Min; Oliveira Passos, Dario; Shan, Zelin; Smith, Steven J; Sun, Qinfang; Biswas, Avik; Choudhuri, Indrani; Strutzenberg, Timothy S; Haldane, Allan; Deng, Nanjie; Li, Zhaoyang; Zhao, Xue Zhi; Briganti, Lorenzo; Kvaratskhelia, Mamuka; Burke Jr, Terrence R; Levy, Ronald M; Hughes, Stephen H; Craigie, Robert; Lyumkis, Dmitry |
Science advances |
37478179 |
2023 Jul 21 |
Integrated Fluorescence Microscopy (iFLM) for Cryo-FIB-milling and In-situ Cryo-ET. |
Yang, Jae; Vrbovská, Veronika; Franke, Tilman; Sibert, Bryan; Larson, Matthew; Hall, Alex; Rigort, Alex; Mitchels, John; Wright, Elizabeth R |
bioRxiv : the preprint server for biology |
37502891 |
2023 Jul 12 |
Handling difficult cryo-ET samples: A study with primary neurons from Drosophila melanogaster. |
Kim, Joseph Y; Yang, Jie E; Mitchell, Josephine W; English, Lauren A; Yang, Sihui Z; Tenpas, Tanner; Dent, Erik W; Wildonger, Jill; Wright, Elizabeth R |
bioRxiv : the preprint server for biology |
37502991 |
2023 Jul 11 |
Atomic-level architecture of Caulobacter crescentus flagellar filaments provide evidence for multi-flagellin filament stabilization. |
Sanchez, Juan C; Montemayor, Eric J; Ploscariu, Nicoleta T; Parrell, Daniel; Baumgardt, Joseph K; Yang, Jie E; Sibert, Bryan; Cai, Kai; Wright, Elizabeth R |
bioRxiv : the preprint server for biology |
37503001 |
2023 Jul 10 |
Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin. |
Neuberger, Arthur; Trofimov, Yury A; Yelshanskaya, Maria V; Khau, Jeffrey; Nadezhdin, Kirill D; Khosrof, Lena S; Krylov, Nikolay A; Efremov, Roman G; Sobolevsky, Alexander I |
Nature communications |
37532722 |
2023 Aug 02 |
Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. |
Baier, Alexander S; Gioacchini, Nathan; Eek, Priit; Tan, Song; Peterson, Craig L |
Research square |
37546845 |
2023 Jul 28 |
Extracellular filaments revealed by affinity capture cryo-electron tomography of lymphocytes. |
Engel, Leeya; Zaoralova, Magda; Dunn, Alexander R; Oliver, Stefan |
bioRxiv : the preprint server for biology |
37577490 |
2023 Aug 06 |
Structural insights into opposing actions of neurosteroids on GABAA receptors. |
Legesse, Dagimhiwat H; Fan, Chen; Teng, Jinfeng; Zhuang, Yuxuan; Howard, Rebecca J; Noviello, Colleen M; Lindahl, Erik; Hibbs, Ryan E |
Nature communications |
37607940 |
2023 Aug 22 |
Developing Technologies for Correlative Cryo-Imaging Pipelines. |
Wright, Elizabeth R; Yang, Jae; Sibert, Bryan; Larson, Matthew; Kim, Joseph Y; Parrell, Daniel; Sanchez, Juan C; Kumar, Anil; Cai, Kai |
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada |
37613235 |
2023 Jul 22 |
The National Center for CryoEM Access and Training - Establishing a Cross-Facility-Honored Training Curriculum. |
Eng, Edward T; Zimanyi, Christina; Aragon, Mahira; Chua, Eugene Y D; Kopylov, Elina; Dubbeldam, Charlie; Castello, Cathleen; Kieft, Jeffrey S; de Marco, Alex |
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada |
37613291 |
2023 Jul 22 |
Cryo-EM Pipeline for Pharmaceutical and Biotechnology Industries. |
Kumar, Anil; Cai, Kai; Larson, Matt R; Sibert, Bryan S; Yang, Jae E; Wright, Elizabeth R |
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada |
37613370 |
2023 Jul 22 |
Structural and Functional Analysis of Flagellar Filaments of Caulobacter crescentus. |
Sanchez, Juan C; Montemayor, Eric J; Ploscariu, Nicoleta T; Parrell, Daniel D; Yang, Jae; Sibert, Bryan; Cai, Kai; Wright, Elizabeth R |
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada |
37613764 |
2023 Jul 22 |
Workflow for High-resolution Sub-volume Averaging from Heterogenous Viral and Virus-like Assemblies. |
Sibert, Bryan S; Kim, Joseph Y; Yang, Jae E; Hannon-Hatfield, Adam; Ke, Zunlong; Garfinkel, David J; Wright, Elizabeth R |
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada |
37613807 |
2023 Jul 22 |
CryoEM structures of the human CLC-2 voltage gated chloride channel reveal a ball and chain gating mechanism. |
Xu, Mengyuan; Neelands, Torben; Powers, Alexander S; Liu, Yan; Miller, Steven D; Pintilie, Grigore; Bois, J Du; Dror, Ron O; Chiu, Wah; Maduke, Merritt |
bioRxiv : the preprint server for biology |
37645939 |
2023 Nov 29 |
Modulation of GluA2-γ5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. |
Gangwar, Shanti Pal; Yen, Laura Y; Yelshanskaya, Maria V; Korman, Aryeh; Jones, Drew R; Sobolevsky, Alexander I |
Nature structural & molecular biology |
37653241 |
2023 Oct |
The Structures of Secretory IgA in complex with Streptococcus pyogenes M4 and human CD89 provide insights on mucosal host-pathogen interactions. |
Liu, Qianqiao; Stadtmueller, Beth M |
bioRxiv : the preprint server for biology |
37662389 |
2023 Aug 26 |
Substrate binding and inhibition of the anion exchanger 1 transporter. |
Capper, Michael J; Yang, Shifan; Stone, Alexander C; Vatansever, Sezen; Zilberg, Gregory; Mathiharan, Yamuna Kalyani; Habib, Raul; Hutchinson, Keino; Zhao, Yihan; Schlessinger, Avner; Mezei, Mihaly; Osman, Roman; Zhang, Bin; Wacker, Daniel |
Nature structural & molecular biology |
37679563 |
2023 Oct |
Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. |
Padi, Sathish K R; Vos, Margaret R; Godek, Rachel J; Fuller, James R; Kruse, Thomas; Hein, Jamin B; Nilsson, Jakob; Kelker, Matthew S; Page, Rebecca; Peti, Wolfgang |
bioRxiv : the preprint server for biology |
37693408 |
2023 Aug 31 |
Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron. |
Patel, Anamika; Kumar, Sanjeev; Lai, Lilin; Keen, Meredith; Valanparambil, Rajesh; Chakravarthy, Chennareddy; Laughlin, Zane; Frank, Filipp; Cheedarla, Narayanaiah; Verkerke, Hans P; Neish, Andrew S; Roback, John D; Davis, Carl W; Wrammert, Jens; Sharma, Amit; Ahmed, Rafi; Suthar, Mehul S; Murali-Krishna, Kaja; Chandele, Anmol; Ortlund, Eric |
Cell reports |
37708028 |
2023 Sep 26 |
Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays. |
Santiago-Frangos, Andrew; Henriques, William S; Wiegand, Tanner; Gauvin, Colin C; Buyukyoruk, Murat; Graham, Ava B; Wilkinson, Royce A; Triem, Lenny; Neselu, Kasahun; Eng, Edward T; Lander, Gabriel C; Wiedenheft, Blake |
Nature structural & molecular biology |
37710013 |
2023 Nov |
Correlative montage parallel array cryo-tomography for in situ structural cell biology. |
Yang, Jie E; Larson, Matthew R; Sibert, Bryan S; Kim, Joseph Y; Parrell, Daniel; Sanchez, Juan C; Pappas, Victoria; Kumar, Anil; Cai, Kai; Thompson, Keith; Wright, Elizabeth R |
Nature methods |
37723245 |
2023 Oct |
Cryo-EM structures reveal native GABAA receptor assemblies and pharmacology. |
Sun, Chang; Zhu, Hongtao; Clark, Sarah; Gouaux, Eric |
Nature |
37730991 |
2023 Oct |
Structural Mechanisms for VMAT2 inhibition by tetrabenazine. |
Dalton, Michael P; Cheng, Mary Hongying; Bahar, Ivet; Coleman, Jonathan A |
bioRxiv : the preprint server for biology |
37732203 |
2023 Sep 05 |
Structural Characterization of Canine Minute Virus, Rat and Porcine Bocavirus. |
Velez, Michael; Mietzsch, Mario; Hsi, Jane; Bell, Logan; Chipman, Paul; Fu, Xiaofeng; McKenna, Robert |
Viruses |
37766206 |
2023 Aug 24 |
C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. |
Consalvo, Claudia D; Aderounmu, Adedeji M; Donelick, Helen M; Aruscavage, P Joe; Eckert, Debra M; Shen, Peter S; Bass, Brenda L |
bioRxiv : the preprint server for biology |
37790392 |
2023 Oct 26 |
Mobile barrier mechanisms for Na+-coupled symport in an MFS sugar transporter. |
Hariharan, Parameswaran; Shi, Yuqi; Katsube, Satoshi; Willibal, Katleen; Burrows, Nathan D; Mitchell, Patrick; Bakhtiiari, Amirhossein; Stanfield, Samantha; Pardon, Els; Kaback, H Ronald; Liang, Ruibin; Steyaert, Jan; Viner, Rosa; Guan, Lan |
bioRxiv : the preprint server for biology |
37790566 |
2023 Nov 25 |
A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM. |
Langeberg, Conner J; Kieft, Jeffrey S |
Nucleic acids research |
37791881 |
2023 Nov 10 |
Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN Domain. |
Small, Gabriel I; Fedorova, Olga; Olinares, Paul Dominic B; Chandanani, Joshua; Banerjee, Anoosha; Choi, Young Joo; Molina, Henrik; Chait, Brian; Darst, Seth A; Campbell, Elizabeth A |
bioRxiv : the preprint server for biology |
37808858 |
2023 Sep 26 |
Structural Determination of Glucosyltransferase C by Cryo-Electron Microscopy. |
Xie, Qing; Cao, Jianhao; Zhang, Hua; Wu, Hui |
Methods in molecular biology (Clifton, N.J.) |
37815721 |
2024 |
Scaling up cryo-EM for biology and chemistry: The journey from niche technology to mainstream method. |
de la Cruz, M Jason; Eng, Edward T |
Structure (London, England : 1993) |
37820731 |
2023 Dec 07 |
Structural basis of promiscuous substrate transport by Organic Cation Transporter 1. |
Zeng, Yi C; Sobti, Meghna; Quinn, Ada; Smith, Nicola J; Brown, Simon H J; Vandenberg, Jamie I; Ryan, Renae M; O'Mara, Megan L; Stewart, Alastair G |
Nature communications |
37821493 |
2023 Oct 11 |
High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology. |
Zhang, Zhemin; Tringides, Marios L; Morgan, Christopher E; Miyagi, Masaru; Mears, Jason A; Hoppel, Charles L; Yu, Edward W |
Molecular & cellular proteomics : MCP |
37839702 |
2023 Dec |
Accurate computational design of three-dimensional protein crystals. |
Li, Zhe; Wang, Shunzhi; Nattermann, Una; Bera, Asim K; Borst, Andrew J; Yaman, Muammer Y; Bick, Matthew J; Yang, Erin C; Sheffler, William; Lee, Byeongdu; Seifert, Soenke; Hura, Greg L; Nguyen, Hannah; Kang, Alex; Dalal, Radhika; Lubner, Joshua M; Hsia, Yang; Haddox, Hugh; Courbet, Alexis; Dowling, Quinton; Miranda, Marcos; Favor, Andrew; Etemadi, Ali; Edman, Natasha I; Yang, Wei; Weidle, Connor; Sankaran, Banumathi; Negahdari, Babak; Ross, Michael B; Ginger, David S; Baker, David |
Nature materials |
37845322 |
2023 Dec |
SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions. |
Liu, Qianqiao; Stadtmueller, Beth M |
Nature communications |
37872175 |
2023 Oct 23 |
A Suite of Designed Protein Cages Using Machine Learning Algorithms and Protein Fragment-Based Protocols. |
Meador, Kyle; Castells-Graells, Roger; Aguirre, Roman; Sawaya, Michael R; Arbing, Mark A; Sherman, Trent; Senarathne, Chethaka; Yeates, Todd O |
bioRxiv : the preprint server for biology |
37873110 |
2023 Oct 09 |
Fabrication of membrane proteins in the form of native cell membrane nanoparticles using novel membrane active polymers. |
Hoang Trinh, Thi Kim; Catalano, Claudio; Guo, Youzhong |
Nanoscale advances |
37881706 |
2023 Oct 24 |
Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. |
Small, Gabriel I; Fedorova, Olga; Olinares, Paul Dominic B; Chandanani, Joshua; Banerjee, Anoosha; Choi, Young Joo; Molina, Henrik; Chait, Brian T; Darst, Seth A; Campbell, Elizabeth A |
Molecular cell |
37890482 |
2023 Nov 02 |
Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions. |
Li, Shibai; Yu, You; Zheng, Jian; Miller-Browne, Victoria; Ser, Zheng; Kuang, Huihui; Patel, Dinshaw J; Zhao, Xiaolan |
Proceedings of the National Academy of Sciences of the United States of America |
37903273 |
2023 Nov 07 |
Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP. |
Hussein, Adel; Fan, Shujie; Lopez-Redondo, Maria; Kenney, Ian; Zhang, Xihui; Beckstein, Oliver; Stokes, David L |
eLife |
37906094 |
2023 Oct 31 |
Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. |
Lu, Jiuwei; Fang, Jian; Zhu, Hongtao; Liang, Kimberly Lu; Khudaverdyan, Nelli; Song, Jikui |
Nucleic acids research |
37941146 |
2023 Dec 11 |
Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. |
Iglesias, Stephano M; Lokareddy, Ravi K; Yang, Ruoyu; Li, Fenglin; Yeggoni, Daniel P; David Hou, Chun-Feng; Leroux, Makayla N; Cortines, Juliana R; Leavitt, Justin C; Bird, Mary; Casjens, Sherwood R; White, Simon; Teschke, Carolyn M; Cingolani, Gino |
Journal of molecular biology |
37952769 |
2023 Dec 15 |
Cryo-electron tomography reveals the structural diversity of cardiac proteins in their cellular context. |
Woldeyes, Rahel A; Nishiga, Masataka; Vander Roest, Alison S; Engel, Leeya; Giri, Prerna; Montenegro, Gabrielle C; Wu, Andrew C; Dunn, Alexander R; Spudich, James A; Bernstein, Daniel; Schmid, Michael F; Wu, Joseph C; Chiu, Wah |
bioRxiv : the preprint server for biology |
37961228 |
2023 Oct 26 |
Molecular Basis of Human Trace Amine-Associated Receptor 1 Activation. |
Zilberg, Gregory; Parpounas, Alexandra K; Warren, Audrey L; Yang, Shifan; Wacker, Daniel |
bioRxiv : the preprint server for biology |
37986760 |
2023 Sep 07 |
Structural Insights into the Unexpected Agonism of Tetracyclic Antidepressants at Serotonin Receptors 5-HT1eR and 5-HT1FR. |
Zilberg, Gregory; Parpounas, Alexandra K; Warren, Audrey L; Fiorillo, Bianca; Provasi, Davide; Filizola, Marta; Wacker, Daniel |
bioRxiv : the preprint server for biology |
37986777 |
2023 Oct 07 |
Tad and toxin-coregulated pilus structures reveal unexpected diversity in bacterial type IV pili. |
Sonani, Ravi R; Sanchez, Juan Carlos; Baumgardt, Joseph K; Kundra, Shivani; Wright, Elizabeth R; Craig, Lisa; Egelman, Edward H |
Proceedings of the National Academy of Sciences of the United States of America |
38011558 |
2023 Dec 05 |
Engineered odorant receptors illuminate structural principles of odor discrimination. |
de March, Claire A; Ma, Ning; Billesbølle, Christian B; Tewari, Jeevan; Del Torrent, Claudia Llinas; van der Velden, Wijnand J C; Ojiro, Ichie; Takayama, Ikumi; Faust, Bryan; Li, Linus; Vaidehi, Nagarajan; Manglik, Aashish; Matsunami, Hiroaki |
bioRxiv : the preprint server for biology |
38014344 |
2023 Nov 17 |
Structural basis for flagellin-induced NAIP5 activation. |
Paidimuddala, Bhaskar; Cao, Jianhao; Zhang, Liman |
Science advances |
38055825 |
2023 Dec 08 |
Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. |
Kretsch, Rachael C; Xu, Lily; Zheludev, Ivan N; Zhou, Xueting; Huang, Rui; Nye, Grace; Li, Shanshan; Zhang, Kaiming; Chiu, Wah; Das, Rhiju |
bioRxiv : the preprint server for biology |
38076883 |
2023 Nov 27 |
Structural dynamics of GluK2 kainate receptors in apo and partial agonist bound states. |
Bogdanović, Nebojša; Segura-Covarrubias, Guadalupe; Zhang, Lisa; Tajima, Nami |
Research square |
38076992 |
2023 Dec 02 |
Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. |
Rosenberg, Gregory M; Abskharon, Romany; Boyer, David R; Ge, Peng; Sawaya, Michael R; Eisenberg, David S |
PNAS nexus |
38077690 |
2023 Dec |
A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. |
Oh, Juntaek; Shan, Zelin; Hoshika, Shuichi; Xu, Jun; Chong, Jenny; Benner, Steven A; Lyumkis, Dmitry; Wang, Dong |
Nature communications |
38086811 |
2023 Dec 12 |
Structures of the promoter-bound respiratory syncytial virus polymerase. |
Cao, Dongdong; Gao, Yunrong; Chen, Zhenhang; Gooneratne, Inesh; Roesler, Claire; Mera, Cristopher; D'Cunha, Paul; Antonova, Anna; Katta, Deepak; Romanelli, Sarah; Wang, Qi; Rice, Samantha; Lemons, Wesley; Ramanathan, Anita; Liang, Bo |
Nature |
38123676 |
2023 Dec 20 |
Product analog binding identifies the copper active site of particulate methane monooxygenase. |
Tucci, Frank J; Jodts, Richard J; Hoffman, Brian M; Rosenzweig, Amy C |
Nature catalysis |
38187819 |
2023 Dec |
Recent advances in infectious disease research using cryo-electron tomography. |
Asarnow, Daniel; Becker, Vada A; Bobe, Daija; Dubbledam, Charlie; Johnston, Jake D; Kopylov, Mykhailo; Lavoie, Nathalie R; Li, Qiuye; Mattingly, Jacob M; Mendez, Joshua H; Paraan, Mohammadreza; Turner, Jack; Upadhye, Viraj; Walsh Jr, Richard M; Gupta, Meghna; Eng, Edward T |
Frontiers in molecular biosciences |
38288336 |
2023 |
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. |
Hoppe, Nicholas; Harrison, Simone; Hwang, Sun-Hee; Chen, Ziwei; Karelina, Masha; Deshpande, Ishan; Suomivuori, Carl-Mikael; Palicharla, Vivek R; Berry, Samuel P; Tschaikner, Philipp; Regele, Dominik; Covey, Douglas F; Stefan, Eduard; Marks, Debora S; Reiter, Jeremy F; Dror, Ron O; Evers, Alex S; Mukhopadhyay, Saikat; Manglik, Aashish |
Nature structural & molecular biology |
38326651 |
2024 Feb 07 |
CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization. |
Serbynovskyi, Viacheslav; Wang, Jing; Chua, Eugene Yd; Ishemgulova, Aygul; Alink, Lambertus M; Budell, William C; Johnston, Jake D; Dubbeldam, Charlie; Gonzalez, Fabio A; Rozovsky, Sharon; Eng, Edward T; de Marco, Alex; Noble, Alex J |
bioRxiv : the preprint server for biology |
38328036 |
2024 Feb 01 |
Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor. |
Mazzaferro, Simone; Kang, Guipeun; Natarajan, Kathiresan; Hibbs, Ryan E; Sine, Steven M |
British journal of pharmacology |
38454578 |
2024 Mar 07 |