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Karolczak J, Przybyłowska A, Szewczyk K, Taisner W, Heumann JM, Stowell MHB, Nowicki M, Brzezinski D |
bioRxiv : the preprint server for biology |
39257821 |
bioRxiv |
2024 Dec 9 |
https://www.ncbi.nlm.nih.gov/pubmed/39257821 |
Ligand identification in CryoEM and X-ray maps using deep learning. |
Karolczak J, Przybyłowska A, Szewczyk K, Taisner W, Heumann JM, Stowell MHB, Nowicki M, Brzezinski D |
Bioinformatics (Oxford, England) |
39700427 |
Bioinformatics |
2024 Dec 26 |
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Cryo-Electron Microscopy Screening Automation across Multiple Grids using Smart Leginon. |
Sawh-Gopal A, Ishemgulova A, Chua EYD, Aragon MF, Mendez JH, Eng ET, Noble AJ |
Journal of visualized experiments : JoVE |
38108412 |
J Vis Exp |
2023 Dec 1 |
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Nature communications |
35387991 |
Nat Commun |
2022 Apr 6 |
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Klykov O, Bobe D, Paraan M, Johnston JD, Potter CS, Carragher B, Kopylov M, Noble AJ |
Bio-protocol |
36618877 |
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2022 Nov 5 |
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Nature structural & molecular biology |
35835865 |
Nat Struct Mol Biol |
2022 Jul |
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Better, Faster, Cheaper: Recent Advances in Cryo-Electron Microscopy. |
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Annu Rev Biochem |
2022 Jun 21 |
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Molecular cell |
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Mol Cell |
2022 Jan 20 |
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The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems. |
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PloS one |
37352230 |
PLoS One |
2023 |
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Quantitative Analysis of Rhodobacter sphaeroides Storage Organelles via Cryo-Electron Tomography and Light Microscopy. |
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Biomolecules |
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Biomolecules |
2024 Aug 14 |
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Molecular sociology of virus-induced cellular condensates supporting reovirus assembly and replication. |
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Nature communications |
39639006 |
Nat Commun |
2024 Dec 6 |
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High-Resolution Cryo-EM Structure Determination of α-synuclein - A Prototypical Amyloid Fibril. |
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bioRxiv : the preprint server for biology |
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2024 Sep 19 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Oct 11 |
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Handling Difficult Cryo-ET Samples: A Study with Primary Neurons from Drosophila melanogaster. |
Kim JY, Yang JE, Mitchell JW, English LA, Yang SZ, Tenpas T, Dent EW, Wildonger J, Wright ER |
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada |
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Microsc Microanal |
2023 Dec 21 |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2023 Dec 5 |
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Journal of visualized experiments : JoVE |
34570100 |
J Vis Exp |
2021 Sep 13 |
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In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment. |
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bioRxiv : the preprint server for biology |
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Bio-protocol |
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2024 Jul 20 |
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Current opinion in structural biology |
39366119 |
Curr Opin Struct Biol |
2024 Dec |
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High-resolution Cryo-EM Structure Determination of a-Synuclein-A Prototypical Amyloid Fibril. |
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Bio-protocol |
39959285 |
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2025 Feb 5 |
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Nature methods |
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Nat Methods |
2023 Oct |
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mBio |
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mBio |
2023 Aug 31 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2023 Jul 10 |
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CorRelator: Interactive software for real-time high precision cryo-correlative light and electron microscopy. |
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Journal of structural biology |
33610654 |
J Struct Biol |
2021 Jun |
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Cryo-electron tomography of stationary phase Burkholderia thailandensis. |
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microPublication biology |
38725941 |
MicroPubl Biol |
2024 |
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Handling difficult cryo-ET samples: A study with primary neurons from Drosophila melanogaster. |
Kim JY, Yang JE, Mitchell JW, English LA, Yang SZ, Tenpas T, Dent EW, Wildonger J, Wright ER |
bioRxiv : the preprint server for biology |
37502991 |
bioRxiv |
2023 Jul 11 |
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The mating pilus of E. coli pED208 acts as a conduit for ssDNA during horizontal gene transfer. |
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mBio |
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2024 Jan 16 |
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Nature communications |
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Nat Commun |
2024 Jul 14 |
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Integrated Fluorescence Microscopy (iFLM) for Cryo-FIB-milling and In-situ Cryo-ET. |
Yang J, Vrbovská V, Franke T, Sibert B, Larson M, Hall A, Rigort A, Mitchels J, Wright ER |
bioRxiv : the preprint server for biology |
37502891 |
bioRxiv |
2023 Jul 12 |
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Structure of the Thin Filament in Human iPSC-derived Cardiomyocytes and its Response to Heart Disease. |
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bioRxiv : the preprint server for biology |
37961228 |
bioRxiv |
2025 Feb 23 |
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In-Situ Structure and Topography of AMPA Receptor Scaffolding Complexes Visualized by CryoET. |
Held RG, Liang J, Esquivies L, Khan YA, Wang C, Azubel M, Brunger AT |
bioRxiv : the preprint server for biology |
39464045 |
bioRxiv |
2024 Oct 22 |
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Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms. |
Bunbury F, Rivas C, Calatrava V, Malkovskiy AV, Joubert LM, Parvate AD, Evans JE, Grossman AR, Bhaya D |
Proceedings of the National Academy of Sciences of the United States of America |
39879238 |
Proc Natl Acad Sci U S A |
2025 Feb 4 |
https://www.ncbi.nlm.nih.gov/pubmed/39879238 |
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Zhao Y, Schmid MF, Chiu W |
Structure (London, England : 1993) |
39644888 |
Structure |
2025 Feb 6 |
https://www.ncbi.nlm.nih.gov/pubmed/39644888 |
Extracellular filaments revealed by affinity capture cryo-electron tomography. |
Engel L, Zaoralová M, Zhou M, Dunn AR, Oliver SL |
bioRxiv : the preprint server for biology |
37577490 |
bioRxiv |
2024 Sep 5 |
https://www.ncbi.nlm.nih.gov/pubmed/37577490 |
Dramatic Changes in Mitochondrial Subcellular Location and Morphology Accompany Activation of the CO(2) Concentrating Mechanism. |
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bioRxiv : the preprint server for biology |
38585955 |
bioRxiv |
2024 Mar 27 |
https://www.ncbi.nlm.nih.gov/pubmed/38585955 |
Dramatic changes in mitochondrial subcellular location and morphology accompany activation of the CO(2) concentrating mechanism. |
Findinier J, Joubert LM, Fakhimi N, Schmid MF, Malkovskiy AV, Chiu W, Burlacot A, Grossman AR |
Proceedings of the National Academy of Sciences of the United States of America |
39405346 |
Proc Natl Acad Sci U S A |
2024 Oct 22 |
https://www.ncbi.nlm.nih.gov/pubmed/39405346 |
Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography. |
Held RG, Liang J, Brunger AT |
Proceedings of the National Academy of Sciences of the United States of America |
38923992 |
Proc Natl Acad Sci U S A |
2024 Jul 2 |
https://www.ncbi.nlm.nih.gov/pubmed/38923992 |
Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery. |
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Nano letters |
32375002 |
Nano Lett |
2020 Jun 10 |
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Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. |
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Nature communications |
33514705 |
Nat Commun |
2021 Jan 29 |
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TRPV3 expression and purification for structure determination by Cryo-EM. |
Neuberger A, Nadezhdin KD, Sobolevsky AI |
Methods in enzymology |
34059288 |
Methods Enzymol |
2021 |
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Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. |
Noviello CM, Gharpure A, Mukhtasimova N, Cabuco R, Baxter L, Borek D, Sine SM, Hibbs RE |
Cell |
33735609 |
Cell |
2021 Apr 15 |
https://www.ncbi.nlm.nih.gov/pubmed/33735609 |
The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. |
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Nature communications |
34417466 |
Nat Commun |
2021 Aug 20 |
https://www.ncbi.nlm.nih.gov/pubmed/34417466 |
An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. |
Morgan CE, Zhang Z, Bonomo RA, Yu EW |
mBio |
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mBio |
2021 Feb 22 |
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Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer. |
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Communications biology |
34887516 |
Commun Biol |
2021 Dec 9 |
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Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy. |
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Methods in enzymology |
34099169 |
Methods Enzymol |
2021 |
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Architecture and assembly mechanism of native glycine receptors. |
Zhu H, Gouaux E |
Nature |
34555840 |
Nature |
2021 Nov |
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Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. |
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ACS chemical biology |
34520180 |
ACS Chem Biol |
2021 Nov 19 |
https://www.ncbi.nlm.nih.gov/pubmed/34520180 |
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The Journal of biological chemistry |
34520757 |
J Biol Chem |
2021 Oct |
https://www.ncbi.nlm.nih.gov/pubmed/34520757 |
Shared structural mechanisms of general anaesthetics and benzodiazepines. |
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Nature |
32879488 |
Nature |
2020 Sep |
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eLife |
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Cryo-EM structures provide insight into how E. coli F(1)F(o) ATP synthase accommodates symmetry mismatch. |
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Nature communications |
32457314 |
Nat Commun |
2020 May 26 |
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BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. |
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Cancer discovery |
35658124 |
Cancer Discov |
2022 Aug 5 |
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Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole. |
Neuberger A, Nadezhdin KD, Sobolevsky AI |
Nature communications |
34725357 |
Nat Commun |
2021 Nov 1 |
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Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation. |
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Science advances |
34452907 |
Sci Adv |
2021 Aug |
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Structural mechanism of muscle nicotinic receptor desensitization and block by curare. |
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Nature structural & molecular biology |
35301478 |
Nat Struct Mol Biol |
2022 Apr |
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Communications biology |
36336763 |
Commun Biol |
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Structural basis for APE1 processing DNA damage in the nucleosome. |
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Nature communications |
36104361 |
Nat Commun |
2022 Sep 14 |
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Structures of the TMC-1 complex illuminate mechanosensory transduction. |
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Nature |
36224384 |
Nature |
2022 Oct |
https://www.ncbi.nlm.nih.gov/pubmed/36224384 |
Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP(2). |
Yin Y, Zhang F, Feng S, Butay KJ, Borgnia MJ, Im W, Lee SY |
Science (New York, N.Y.) |
36227998 |
Science |
2022 Oct 14 |
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Superimmunity by pan-sarbecovirus nanobodies. |
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Cell reports |
35738279 |
Cell Rep |
2022 Jun 28 |
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Computational design of mechanically coupled axle-rotor protein assemblies. |
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Science (New York, N.Y.) |
35446645 |
Science |
2022 Apr 22 |
https://www.ncbi.nlm.nih.gov/pubmed/35446645 |
High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology. |
Zhang Z, Tringides ML, Morgan CE, Miyagi M, Mears JA, Hoppel CL, Yu EW |
Molecular & cellular proteomics : MCP |
37839702 |
Mol Cell Proteomics |
2023 Dec |
https://www.ncbi.nlm.nih.gov/pubmed/37839702 |
Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. |
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Journal of molecular biology |
37952769 |
J Mol Biol |
2023 Dec 15 |
https://www.ncbi.nlm.nih.gov/pubmed/37952769 |
Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy. |
Schnicker NJ, Xu Z, Amir M, Gakhar L, Huang CL |
bioRxiv : the preprint server for biology |
38496408 |
bioRxiv |
2024 Mar 6 |
https://www.ncbi.nlm.nih.gov/pubmed/38496408 |
The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. |
Cruz VE, Weirich CS, Peddada N, Erzberger JP |
Nature communications |
38632236 |
Nat Commun |
2024 Apr 17 |
https://www.ncbi.nlm.nih.gov/pubmed/38632236 |
Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast. |
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RNA (New York, N.Y.) |
38688558 |
RNA |
2024 Jul 16 |
https://www.ncbi.nlm.nih.gov/pubmed/38688558 |
Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5. |
Paidimuddala B, Cao J, Nash G, Xie Q, Wu H, Zhang L |
Nature structural & molecular biology |
36604500 |
Nat Struct Mol Biol |
2023 Feb |
https://www.ncbi.nlm.nih.gov/pubmed/36604500 |
Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1. |
Srivastava D, Yadav RP, Singh S, Boyd K, Artemyev NO |
Structure (London, England : 1993) |
36657440 |
Structure |
2023 Mar 2 |
https://www.ncbi.nlm.nih.gov/pubmed/36657440 |
The molecular mechanism of sialic acid transport mediated by Sialin. |
Hu W, Chi C, Song K, Zheng H |
Science advances |
36662855 |
Sci Adv |
2023 Jan 20 |
https://www.ncbi.nlm.nih.gov/pubmed/36662855 |
Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme. |
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bioRxiv : the preprint server for biology |
37066309 |
bioRxiv |
2023 Apr 5 |
https://www.ncbi.nlm.nih.gov/pubmed/37066309 |
A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM. |
Langeberg CJ, Kieft JS |
Nucleic acids research |
37791881 |
Nucleic Acids Res |
2023 Nov 10 |
https://www.ncbi.nlm.nih.gov/pubmed/37791881 |
Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of Methylococcus capsulatus Soluble Methane Monooxygenase Hydroxylase. |
Ahn E, Kim B, Park S, Erwin AL, Sung SH, Hovden R, Mosalaganti S, Cho US |
ACS nano |
36926824 |
ACS Nano |
2023 Mar 28 |
https://www.ncbi.nlm.nih.gov/pubmed/36926824 |
Structural basis for flagellin induced NAIP5 activation. |
Paidimuddala B, Cao J, Zhang L |
bioRxiv : the preprint server for biology |
37398004 |
bioRxiv |
2023 Jun 13 |
https://www.ncbi.nlm.nih.gov/pubmed/37398004 |
Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants. |
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Proceedings of the National Academy of Sciences of the United States of America |
37436958 |
Proc Natl Acad Sci U S A |
2023 Jul 18 |
https://www.ncbi.nlm.nih.gov/pubmed/37436958 |
Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. |
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Proceedings of the National Academy of Sciences of the United States of America |
37450495 |
Proc Natl Acad Sci U S A |
2023 Jul 18 |
https://www.ncbi.nlm.nih.gov/pubmed/37450495 |
Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. |
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Research square |
37546845 |
Res Sq |
2023 Jul 28 |
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Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. |
Padi SKR, Vos MR, Godek RJ, Fuller JR, Kruse T, Hein JB, Nilsson J, Kelker MS, Page R, Peti W |
Nature |
38123684 |
Nature |
2024 Jan |
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B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. |
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Proceedings of the National Academy of Sciences of the United States of America |
38150499 |
Proc Natl Acad Sci U S A |
2024 Jan 2 |
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Mechanism of anion exchange and small-molecule inhibition of pendrin. |
Wang L, Hoang A, Gil-Iturbe E, Laganowsky A, Quick M, Zhou M |
Nature communications |
38184688 |
Nat Commun |
2024 Jan 6 |
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Structural basis for flagellin-induced NAIP5 activation. |
Paidimuddala B, Cao J, Zhang L |
Science advances |
38055825 |
Sci Adv |
2023 Dec 8 |
https://www.ncbi.nlm.nih.gov/pubmed/38055825 |
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis. |
Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski P, Chhapra F, Saelices L |
bioRxiv : the preprint server for biology |
38496656 |
bioRxiv |
2024 Mar 9 |
https://www.ncbi.nlm.nih.gov/pubmed/38496656 |
TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site. |
Nadezhdin KD, Neuberger A, Khosrof LS, Talyzina IA, Khau J, Yelshanskaya MV, Sobolevsky AI |
Science advances |
38691614 |
Sci Adv |
2024 May 3 |
https://www.ncbi.nlm.nih.gov/pubmed/38691614 |
Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C. |
Baier AS, Gioacchini N, Eek P, Leith EM, Tan S, Peterson CL |
eLife |
38809771 |
Elife |
2024 May 29 |
https://www.ncbi.nlm.nih.gov/pubmed/38809771 |
Structural and Biochemical Characterization of the Nucleosome Containing Variants H3.3 and H2A.Z. |
Jung H, Sokolova V, Lee G, Stevens VR, Tan D |
Epigenomes |
38920622 |
Epigenomes |
2024 May 27 |
https://www.ncbi.nlm.nih.gov/pubmed/38920622 |
Structural basis for inhibition of coagulation factor VIII reveals a shared antigenic hotspot on the C1 domain. |
Childers KC, Cowper B, Vaughan JD, McGill JR, Davulcu O, Lollar P, Doering CB, Coxon CH, Spiegel PC Jr |
Journal of thrombosis and haemostasis : JTH |
38849084 |
J Thromb Haemost |
2024 Sep |
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Multi-layered heterochromatin interaction as a switch for DIM2-mediated DNA methylation. |
Shao Z, Lu J, Khudaverdyan N, Song J |
Nature communications |
39122718 |
Nat Commun |
2024 Aug 9 |
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Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel. |
Karuppan S, Schrag LG, Pastrano CM, Jara-Oseguera A, Zubcevic L |
Proceedings of the National Academy of Sciences of the United States of America |
38923985 |
Proc Natl Acad Sci U S A |
2024 Jul 2 |
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Structural basis for Retriever-SNX17 assembly and endosomal sorting. |
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Nature communications |
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Nat Commun |
2024 Nov 25 |
https://www.ncbi.nlm.nih.gov/pubmed/39587083 |
Trapping of spermine, Kukoamine A, and polyamine toxin blockers in GluK2 kainate receptor channels. |
Gangwar SP, Yelshanskaya MV, Aktolun M, Yen LY, Newton TP, Strømgaard K, Kurnikova MG, Sobolevsky AI |
Nature communications |
39592599 |
Nat Commun |
2024 Nov 26 |
https://www.ncbi.nlm.nih.gov/pubmed/39592599 |
Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding. |
Oken AC, Lisi NE, Ditter IA, Shi H, Nechiporuk NA, Mansoor SE |
Nature communications |
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Nat Commun |
2024 Oct 1 |
https://www.ncbi.nlm.nih.gov/pubmed/39353889 |
Streptococcus pneumoniae GAPN is a key metabolic player necessary for host infection. |
Lee E, Saviola A, Bevers S, Redzic JS, Maroney SP, Shaw S, Tamkin E, Fulte S, Nemkov T, Meyer N, D'Alessandro A, Hansen KC, Clark SE, Eisenmesser E |
Protein science : a publication of the Protein Society |
39660954 |
Protein Sci |
2025 Jan |
https://www.ncbi.nlm.nih.gov/pubmed/39660954 |
Structures of methane and ammonia monooxygenases in native membranes. |
Tucci FJ, Rosenzweig AC |
Proceedings of the National Academy of Sciences of the United States of America |
39739801 |
Proc Natl Acad Sci U S A |
2025 Jan 7 |
https://www.ncbi.nlm.nih.gov/pubmed/39739801 |
Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy. |
Schnicker NJ, Xu Z, Amir M, Gakhar L, Huang CL |
Scientific reports |
39747283 |
Sci Rep |
2025 Jan 2 |
https://www.ncbi.nlm.nih.gov/pubmed/39747283 |
Water-directed pinning is key to tau prion formation. |
Vigers MP, Lobo S, Najafi S, Dubose A, Tsay K, Ganguly P, Longhini AP, Jin Y, Buratto SK, Kosik KS, Shell MS, Shea JE, Han S |
Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2025 May 6 |
https://www.ncbi.nlm.nih.gov/pubmed/40294272 |
Structural insights into opposing actions of neurosteroids on GABA(A) receptors. |
Legesse DH, Fan C, Teng J, Zhuang Y, Howard RJ, Noviello CM, Lindahl E, Hibbs RE |
Nature communications |
37607940 |
Nat Commun |
2023 Aug 22 |
https://www.ncbi.nlm.nih.gov/pubmed/37607940 |
Structural Determination of Glucosyltransferase C by Cryo-Electron Microscopy. |
Xie Q, Cao J, Zhang H, Wu H |
Methods in molecular biology (Clifton, N.J.) |
37815721 |
Methods Mol Biol |
2024 |
https://www.ncbi.nlm.nih.gov/pubmed/37815721 |
Energy coupling and stoichiometry of Zn(2+)/H(+) antiport by the prokaryotic cation diffusion facilitator YiiP. |
Hussein A, Fan S, Lopez-Redondo M, Kenney I, Zhang X, Beckstein O, Stokes DL |
eLife |
37906094 |
Elife |
2023 Oct 31 |
https://www.ncbi.nlm.nih.gov/pubmed/37906094 |
Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex. |
Patel AB, Qing J, Tam KH, Zaman S, Luiso M, Radhakrishnan I, He Y |
Nature communications |
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Nat Commun |
2023 May 27 |
https://www.ncbi.nlm.nih.gov/pubmed/37244892 |
Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin. |
Neuberger A, Trofimov YA, Yelshanskaya MV, Khau J, Nadezhdin KD, Khosrof LS, Krylov NA, Efremov RG, Sobolevsky AI |
Nature communications |
37532722 |
Nat Commun |
2023 Aug 2 |
https://www.ncbi.nlm.nih.gov/pubmed/37532722 |
Virion glycosylation influences mycobacteriophage immune recognition. |
Freeman KG, Robotham AC, Parks OB, Abad L, Jacobs-Sera D, Lauer MJ, Podgorski JM, Zhang Y, Williams JV, White SJ, Kelly JF, Hatfull GF, Pope WH |
Cell host & microbe |
37329881 |
Cell Host Microbe |
2023 Jul 12 |
https://www.ncbi.nlm.nih.gov/pubmed/37329881 |
Structure of human TRPV4 in complex with GTPase RhoA. |
Nadezhdin KD, Talyzina IA, Parthasarathy A, Neuberger A, Zhang DX, Sobolevsky AI |
Nature communications |
37353478 |
Nat Commun |
2023 Jun 23 |
https://www.ncbi.nlm.nih.gov/pubmed/37353478 |
Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ. |
Chen S, Vogt A, Lee L, Naila T, McKeown R, Tomkinson AE, Lees-Miller SP, He Y |
Science advances |
37256947 |
Sci Adv |
2023 Jun 2 |
https://www.ncbi.nlm.nih.gov/pubmed/37256947 |
Structural interplay of anesthetics and paralytics on muscle nicotinic receptors. |
Goswami U, Rahman MM, Teng J, Hibbs RE |
Nature communications |
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Nat Commun |
2023 Jun 1 |
https://www.ncbi.nlm.nih.gov/pubmed/37264005 |
Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer. |
Koo CW, Tucci FJ, He Y, Rosenzweig AC |
Science (New York, N.Y.) |
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Science |
2022 Mar 18 |
https://www.ncbi.nlm.nih.gov/pubmed/35298269 |
Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria. |
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Nature communications |
36192412 |
Nat Commun |
2022 Oct 3 |
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Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography. |
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eLife |
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Elife |
2021 Dec 29 |
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Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter. |
Thaker TM, Mishra S, Zhou W, Mohan M, Tang Q, Faraldo-Goméz JD, Mchaourab HS, Tomasiak TM |
Nature chemical biology |
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Nat Chem Biol |
2022 Feb |
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Structure of an endogenous mycobacterial MCE lipid transporter. |
Chen J, Fruhauf A, Fan C, Ponce J, Ueberheide B, Bhabha G, Ekiert D |
Research square |
36711512 |
Res Sq |
2023 Jan 10 |
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Cryo-EM structure of adeno-associated virus 4 at 2.2 Å resolution. |
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Acta crystallographica. Section D, Structural biology |
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Acta Crystallogr D Struct Biol |
2023 Feb 1 |
https://www.ncbi.nlm.nih.gov/pubmed/36762860 |
rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. |
Sekulski K, Cruz VE, Weirich CS, Erzberger JP |
Nature communications |
36864048 |
Nat Commun |
2023 Mar 2 |
https://www.ncbi.nlm.nih.gov/pubmed/36864048 |
Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain. |
Harris NJ, Jenkins ML, Nam SE, Rathinaswamy MK, Parson MA, Ranga-Prasad H, Dalwadi U, Moeller BE, Sheekey E, Hansen SD, Yip CK, Burke JE |
bioRxiv : the preprint server for biology |
37090531 |
bioRxiv |
2023 May 23 |
https://www.ncbi.nlm.nih.gov/pubmed/37090531 |
Structural basis of sensory receptor evolution in octopus. |
Allard CAH, Kang G, Kim JJ, Valencia-Montoya WA, Hibbs RE, Bellono NW |
Nature |
37045920 |
Nature |
2023 Apr |
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Human TRPV1 structure and inhibition by the analgesic SB-366791. |
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Nature communications |
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Nat Commun |
2023 Apr 28 |
https://www.ncbi.nlm.nih.gov/pubmed/37117175 |
Cryo-EM structure of the human Sirtuin 6-nucleosome complex. |
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Science advances |
37058572 |
Sci Adv |
2023 Apr 14 |
https://www.ncbi.nlm.nih.gov/pubmed/37058572 |
Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA. |
Bonilla SL, Vicens Q, Kieft JS |
Science advances |
36026457 |
Sci Adv |
2022 Aug 26 |
https://www.ncbi.nlm.nih.gov/pubmed/36026457 |
Inhibition of the proton-activated chloride channel PAC by PIP(2). |
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eLife |
36633397 |
Elife |
2023 Jan 12 |
https://www.ncbi.nlm.nih.gov/pubmed/36633397 |
30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. |
Srinivas P, Nosrati M, Zelinskaya N, Dey D, Comstock LR, Dunham CM, Conn GL |
bioRxiv : the preprint server for biology |
36993224 |
bioRxiv |
2023 Apr 30 |
https://www.ncbi.nlm.nih.gov/pubmed/36993224 |
Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. |
Zhan H, Unchwaniwala N, Rebolledo-Viveros A, Pennington J, Horswill M, Broadberry R, Myers J, den Boon JA, Grant T, Ahlquist P |
Proceedings of the National Academy of Sciences of the United States of America |
36693094 |
Proc Natl Acad Sci U S A |
2023 Jan 31 |
https://www.ncbi.nlm.nih.gov/pubmed/36693094 |
The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation. |
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Nature communications |
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Nat Commun |
2022 Mar 11 |
https://www.ncbi.nlm.nih.gov/pubmed/35277487 |
Cryo-EM structure of the prothrombin-prothrombinase complex. |
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Blood |
35427420 |
Blood |
2022 Jun 16 |
https://www.ncbi.nlm.nih.gov/pubmed/35427420 |
Architecture of the linker-scaffold in the nuclear pore. |
Petrovic S, Samanta D, Perriches T, Bley CJ, Thierbach K, Brown B, Nie S, Mobbs GW, Stevens TA, Liu X, Tomaleri GP, Schaus L, Hoelz A |
Science (New York, N.Y.) |
35679425 |
Science |
2022 Jun 10 |
https://www.ncbi.nlm.nih.gov/pubmed/35679425 |
Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody. |
Callaway HM, Zyla D, Larrous F, de Melo GD, Hastie KM, Avalos RD, Agarwal A, Corti D, Bourhy H, Saphire EO |
Science advances |
35714192 |
Sci Adv |
2022 Jun 17 |
https://www.ncbi.nlm.nih.gov/pubmed/35714192 |
Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. |
Ren Z, Chhetri A, Guan Z, Suo Y, Yokoyama K, Lee SY |
Nature structural & molecular biology |
35788183 |
Nat Struct Mol Biol |
2022 Jul |
https://www.ncbi.nlm.nih.gov/pubmed/35788183 |
Structural basis of chromatin regulation by histone variant H2A.Z. |
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Nucleic acids research |
34643712 |
Nucleic Acids Res |
2021 Nov 8 |
https://www.ncbi.nlm.nih.gov/pubmed/34643712 |
Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide. |
Zhao Y, Roy K, Vidossich P, Cancedda L, De Vivo M, Forbush B, Cao E |
Nature communications |
35585053 |
Nat Commun |
2022 May 18 |
https://www.ncbi.nlm.nih.gov/pubmed/35585053 |
Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. |
Nadezhdin KD, Neuberger A, Trofimov YA, Krylov NA, Sinica V, Kupko N, Vlachova V, Zakharian E, Efremov RG, Sobolevsky AI |
Nature structural & molecular biology |
34239124 |
Nat Struct Mol Biol |
2021 Jul |
https://www.ncbi.nlm.nih.gov/pubmed/34239124 |
Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. |
Lopez-Redondo M, Fan S, Koide A, Koide S, Beckstein O, Stokes DL |
The Journal of general physiology |
34254979 |
J Gen Physiol |
2021 Aug 2 |
https://www.ncbi.nlm.nih.gov/pubmed/34254979 |
Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment. |
Sharif H, Hollingsworth LR, Griswold AR, Hsiao JC, Wang Q, Bachovchin DA, Wu H |
Immunity |
34019797 |
Immunity |
2021 Jul 13 |
https://www.ncbi.nlm.nih.gov/pubmed/34019797 |
Cryo-EM structure of a thermostable bacterial nanocompartment. |
Wiryaman T, Toor N |
IUCrJ |
33953921 |
IUCrJ |
2021 May 1 |
https://www.ncbi.nlm.nih.gov/pubmed/33953921 |
Light-coupled cryo-plunger for time-resolved cryo-EM. |
Yoder N, Jalali-Yazdi F, Noreng S, Houser A, Baconguis I, Gouaux E |
Journal of structural biology |
32950604 |
J Struct Biol |
2020 Dec 1 |
https://www.ncbi.nlm.nih.gov/pubmed/32950604 |
Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. |
Yang C, Fujiwara R, Kim HJ, Basnet P, Zhu Y, Gorbea Colón JJ, Steimle S, Garcia BA, Kaplan CD, Murakami K |
Molecular cell |
35051353 |
Mol Cell |
2022 Feb 3 |
https://www.ncbi.nlm.nih.gov/pubmed/35051353 |
Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. |
Hu Q, Botuyan MV, Zhao D, Cui G, Mer E, Mer G |
Nature |
34321665 |
Nature |
2021 Aug |
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DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. |
Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H |
Nature |
33731932 |
Nature |
2021 Apr |
https://www.ncbi.nlm.nih.gov/pubmed/33731932 |
Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication. |
Unchwaniwala N, Zhan H, Pennington J, Horswill M, den Boon JA, Ahlquist P |
Proceedings of the National Academy of Sciences of the United States of America |
32690711 |
Proc Natl Acad Sci U S A |
2020 Aug 4 |
https://www.ncbi.nlm.nih.gov/pubmed/32690711 |
Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. |
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S |
Molecular cell |
33373584 |
Mol Cell |
2021 Feb 4 |
https://www.ncbi.nlm.nih.gov/pubmed/33373584 |
Focusing antibody responses to the fusion peptide in rhesus macaques. |
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bioRxiv : the preprint server for biology |
37425865 |
bioRxiv |
2023 Jun 27 |
https://www.ncbi.nlm.nih.gov/pubmed/37425865 |
Structural basis for human NKCC1 inhibition by loop diuretic drugs. |
Zhao Y, Vidossich P, Forbush B, Ma J, Rinehart J, De Vivo M, Cao E |
The EMBO journal |
39875725 |
EMBO J |
2025 Mar |
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Human calpain-3 and its structural plasticity: Dissociation of a homohexamer into dimers on binding titin. |
Ye Q, Henrickson A, Demeler B, Balasco Serrão VH, Davies PL |
The Journal of biological chemistry |
39725035 |
J Biol Chem |
2025 Feb |
https://www.ncbi.nlm.nih.gov/pubmed/39725035 |
Structural and functional dynamics of human cone cGMP-phosphodiesterase important for photopic vision. |
Singh S, Srivastava D, Boyd K, Artemyev NO |
Proceedings of the National Academy of Sciences of the United States of America |
39739818 |
Proc Natl Acad Sci U S A |
2025 Jan 7 |
https://www.ncbi.nlm.nih.gov/pubmed/39739818 |
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket. |
Shi H, Ditter IA, Oken AC, Mansoor SE |
Science advances |
39823330 |
Sci Adv |
2025 Jan 17 |
https://www.ncbi.nlm.nih.gov/pubmed/39823330 |
Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization. |
Lanning S, Aguilar-Hernández N, Serrão VHB, López T, O'Rourke SM, Lentz A, Ricemeyer L, Espinosa R, López S, Arias CF, DuBois RM |
Journal of virology |
39846739 |
J Virol |
2025 Feb 25 |
https://www.ncbi.nlm.nih.gov/pubmed/39846739 |
AI-based discovery and cryoEM structural elucidation of a K(ATP) channel pharmacochaperone. |
Elsheikh A, Driggers CM, Truong HH, Yang Z, Allen J, Henriksen NM, Walczewska-Szewc K, Shyng SL |
eLife |
40135739 |
Elife |
2025 Mar 26 |
https://www.ncbi.nlm.nih.gov/pubmed/40135739 |
Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin. |
Tonggu L, Wisedchaisri G, Gamal El-Din TM, Lenaeus MJ, Logan MM, Toma T, Du Bois J, Zheng N, Catterall WA |
Nature communications |
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Nat Commun |
2024 Mar 14 |
https://www.ncbi.nlm.nih.gov/pubmed/38485923 |
Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2. |
Hu W, Song A, Zheng H |
Nature communications |
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Nat Commun |
2024 Apr 29 |
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VitroJet: new features and case studies. |
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Acta crystallographica. Section D, Structural biology |
38488730 |
Acta Crystallogr D Struct Biol |
2024 Apr 1 |
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Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation. |
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Cell |
38382524 |
Cell |
2024 Feb 29 |
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Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor. |
Mazzaferro S, Kang G, Natarajan K, Hibbs RE, Sine SM |
British journal of pharmacology |
38454578 |
Br J Pharmacol |
2024 Jul |
https://www.ncbi.nlm.nih.gov/pubmed/38454578 |
Dynamic fibrillar assembly of αB-crystallin induced by perturbation of the conserved NT-IXI motif resolved by cryo-EM. |
McFarland R, Reichow S |
bioRxiv : the preprint server for biology |
38585788 |
bioRxiv |
2024 Mar 27 |
https://www.ncbi.nlm.nih.gov/pubmed/38585788 |
ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity. |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 May 14 |
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Structure of the human dopamine transporter and mechanisms of inhibition. |
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Nature |
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Nature |
2024 Aug |
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Cryo-EM reveals a phosphorylated R-domain envelops the NBD1 catalytic domain in an ABC transporter. |
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Life science alliance |
39209537 |
Life Sci Alliance |
2024 Nov |
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RNA (New York, N.Y.) |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Sep 12 |
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Science advances |
39365862 |
Sci Adv |
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Science (New York, N.Y.) |
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2024 May 17 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Apr 2 |
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bioRxiv : the preprint server for biology |
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Nature |
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Nature |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Nucleic Acids Res |
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Molecular cell |
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Mol Cell |
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Nature |
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Nature communications |
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Nat Commun |
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Nature communications |
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Molecular cell |
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Nature |
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Nature communications |
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Nat Commun |
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bioRxiv : the preprint server for biology |
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bioRxiv : the preprint server for biology |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Communications biology |
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Commun Biol |
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Nature communications |
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Nature communications |
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Nature communications |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Molecular cell |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Cell |
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Nature communications |
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Nature communications |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Nature communications |
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Nature communications |
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Nat Commun |
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Structural and dynamic mechanisms of GABA(A) receptor modulators with opposing activities. |
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Nature communications |
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Nat Commun |
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Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation. |
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Nature communications |
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Journal of molecular biology |
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J Mol Biol |
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Methotrexate recognition by the human reduced folate carrier SLC19A1. |
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Nature |
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Nature |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Scientific reports |
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Sci Rep |
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Nature |
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Nature |
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Structural mechanisms for VMAT2 inhibition by tetrabenazine. |
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bioRxiv : the preprint server for biology |
37732203 |
bioRxiv |
2024 Feb 1 |
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C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA. |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Nature chemical biology |
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Nat Chem Biol |
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Nature chemical biology |
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Nat Chem Biol |
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Research square |
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Science advances |
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Sci Adv |
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Nature |
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Nature structural & molecular biology |
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Nature |
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Nature |
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Nature communications |
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bioRxiv : the preprint server for biology |
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Communications biology |
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Commun Biol |
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Structural basis for transcription activation through cooperative recruitment of MntR. |
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Nat Commun |
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Nat Commun |
2022 Aug 15 |
https://www.ncbi.nlm.nih.gov/pubmed/35970990 |
Structure of the human cation-chloride cotransport KCC1 in an outward-open state. |
Zhao Y, Shen J, Wang Q, Ruiz Munevar MJ, Vidossich P, De Vivo M, Zhou M, Cao E |
Proceedings of the National Academy of Sciences of the United States of America |
35759661 |
Proc Natl Acad Sci U S A |
2022 Jul 5 |
https://www.ncbi.nlm.nih.gov/pubmed/35759661 |
Transient Prenyltransferase-Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase. |
Faylo JL, van Eeuwen T, Gupta K, Murakami K, Christianson DW |
Biochemistry |
36227241 |
Biochemistry |
2022 Nov 1 |
https://www.ncbi.nlm.nih.gov/pubmed/36227241 |
HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases. |
Rathinaswamy MK, Fleming KD, Dalwadi U, Pardon E, Harris NJ, Yip CK, Steyaert J, Burke JE |
Structure (London, England : 1993) |
34348129 |
Structure |
2021 Dec 2 |
https://www.ncbi.nlm.nih.gov/pubmed/34348129 |
Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P(2) and rapamycin. |
Gan N, Han Y, Zeng W, Wang Y, Xue J, Jiang Y |
Proceedings of the National Academy of Sciences of the United States of America |
35131932 |
Proc Natl Acad Sci U S A |
2022 Feb 15 |
https://www.ncbi.nlm.nih.gov/pubmed/35131932 |
A Robust Single-Particle Cryo-Electron Microscopy (cryo-EM) Processing Workflow with cryoSPARC, RELION, and Scipion. |
DiIorio MC, Kulczyk AW |
Journal of visualized experiments : JoVE |
35104261 |
J Vis Exp |
2022 Jan 31 |
https://www.ncbi.nlm.nih.gov/pubmed/35104261 |
Gating choreography and mechanism of the human proton-activated chloride channel ASOR. |
Wang C, Polovitskaya MM, Delgado BD, Jentsch TJ, Long SB |
Science advances |
35108041 |
Sci Adv |
2022 Feb 4 |
https://www.ncbi.nlm.nih.gov/pubmed/35108041 |
Structural basis of long-range to short-range synaptic transition in NHEJ. |
Chen S, Lee L, Naila T, Fishbain S, Wang A, Tomkinson AE, Lees-Miller SP, He Y |
Nature |
33854234 |
Nature |
2021 May |
https://www.ncbi.nlm.nih.gov/pubmed/33854234 |
Structural insight on assembly-line catalysis in terpene biosynthesis. |
Faylo JL, van Eeuwen T, Kim HJ, Gorbea Colón JJ, Garcia BA, Murakami K, Christianson DW |
Nature communications |
34108468 |
Nat Commun |
2021 Jun 9 |
https://www.ncbi.nlm.nih.gov/pubmed/34108468 |
Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM. |
Shen BW, Quispe JD, Luyten Y, McGough BE, Morgan RD, Stoddard BL |
Structure (London, England : 1993) |
33826880 |
Structure |
2021 Jun 3 |
https://www.ncbi.nlm.nih.gov/pubmed/33826880 |
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel. |
Liu C, Reese R, Vu S, Rougé L, Shields SD, Kakiuchi-Kiyota S, Chen H, Johnson K, Shi YP, Chernov-Rogan T, Greiner DMZ, Kohli PB, Hackos D, Brillantes B, Tam C, Li T, Wang J, Safina B, Magnuson S, Volgraf M, Payandeh J, Zheng J, Rohou A, Chen J |
Neuron |
33152265 |
Neuron |
2021 Jan 20 |
https://www.ncbi.nlm.nih.gov/pubmed/33152265 |
The Structure of an AAV5-AAVR Complex at 2.5 Å Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors. |
Silveria MA, Large EE, Zane GM, White TA, Chapman MS |
Viruses |
33218165 |
Viruses |
2020 Nov 18 |
https://www.ncbi.nlm.nih.gov/pubmed/33218165 |
Adeno-Associated Virus (AAV-DJ)-Cryo-EM Structure at 1.56 Å Resolution. |
Xie Q, Yoshioka CK, Chapman MS |
Viruses |
33092282 |
Viruses |
2020 Oct 20 |
https://www.ncbi.nlm.nih.gov/pubmed/33092282 |
Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery. |
Herrera M, Kim J, Eygeris Y, Jozic A, Sahay G |
Biomaterials science |
33586742 |
Biomater Sci |
2021 Jun 15 |
https://www.ncbi.nlm.nih.gov/pubmed/33586742 |
Structure of the human Mediator-bound transcription preinitiation complex. |
Abdella R, Talyzina A, Chen S, Inouye CJ, Tjian R, He Y |
Science (New York, N.Y.) |
33707221 |
Science |
2021 Apr 2 |
https://www.ncbi.nlm.nih.gov/pubmed/33707221 |
Structure and assembly of a bacterial gasdermin pore. |
Johnson AG, Mayer ML, Schaefer SL, McNamara-Bordewick NK, Hummer G, Kranzusch PJ |
bioRxiv : the preprint server for biology |
37131678 |
bioRxiv |
2023 Oct 26 |
https://www.ncbi.nlm.nih.gov/pubmed/37131678 |
Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor. |
Childers KC, Avery NG, Estrada Alamo KA, Davulcu O, Haynes RM, Lollar P, Doering CB, Coxon CH, Spiegel PC |
Blood |
37192299 |
Blood |
2023 Jul 13 |
https://www.ncbi.nlm.nih.gov/pubmed/37192299 |
Cryo-EM reveals the molecular basis oflaminin polymerization and LN-lamininopathies. |
Kulczyk AW, McKee KK, Zhang X, Bizukojc I, Yu YQ, Yurchenco PD |
Nature communications |
36658135 |
Nat Commun |
2023 Jan 19 |
https://www.ncbi.nlm.nih.gov/pubmed/36658135 |
Structural basis of promiscuous substrate transport by Organic Cation Transporter 1. |
Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O'Mara ML, Stewart AG |
Nature communications |
37821493 |
Nat Commun |
2023 Oct 11 |
https://www.ncbi.nlm.nih.gov/pubmed/37821493 |
A strategic approach for efficient cryo-EM grid optimization using design of experiments. |
Haynes RM, Myers J, López CS, Evans J, Davulcu O, Yoshioka C |
Journal of structural biology |
38364988 |
J Struct Biol |
2025 Mar |
https://www.ncbi.nlm.nih.gov/pubmed/38364988 |
Structure and assembly of a bacterial gasdermin pore. |
Johnson AG, Mayer ML, Schaefer SL, McNamara-Bordewick NK, Hummer G, Kranzusch PJ |
Nature |
38509367 |
Nature |
2024 Apr |
https://www.ncbi.nlm.nih.gov/pubmed/38509367 |
Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. |
Li FKK, Worrall LJ, Gale RT, Brown ED, Strynadka NCJ |
Science advances |
38416829 |
Sci Adv |
2024 Mar |
https://www.ncbi.nlm.nih.gov/pubmed/38416829 |
Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. |
Padi SKR, Vos MR, Godek RJ, Fuller JR, Kruse T, Hein JB, Nilsson J, Kelker MS, Page R, Peti W |
bioRxiv : the preprint server for biology |
37693408 |
bioRxiv |
2023 Aug 31 |
https://www.ncbi.nlm.nih.gov/pubmed/37693408 |
Structural mechanisms for VMAT2 inhibition by tetrabenazine. |
Dalton MP, Cheng MH, Bahar I, Coleman JA |
eLife |
38517752 |
Elife |
2024 Mar 22 |
https://www.ncbi.nlm.nih.gov/pubmed/38517752 |
Structural basis for Retriever-SNX17 assembly and endosomal sorting. |
Singla A, Boesch DJ, Joyce Fung HY, Ngoka C, Enriquez AS, Song R, Kramer DA, Han Y, Juneja P, Billadeau DD, Bai X, Chen Z, Turer EE, Burstein E, Chen B |
bioRxiv : the preprint server for biology |
38559023 |
bioRxiv |
2024 Mar 13 |
https://www.ncbi.nlm.nih.gov/pubmed/38559023 |
Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation. |
Talyzina A, Han Y, Banerjee C, Fishbain S, Reyes A, Vafabakhsh R, He Y |
Molecular cell |
37402369 |
Mol Cell |
2023 Aug 3 |
https://www.ncbi.nlm.nih.gov/pubmed/37402369 |
Cross-protective antibodies against common endemic respiratory viruses. |
Cabán M, Rodarte JV, Bibby M, Gray MD, Taylor JJ, Pancera M, Boonyaratanakornkit J |
Nature communications |
36781872 |
Nat Commun |
2023 Feb 13 |
https://www.ncbi.nlm.nih.gov/pubmed/36781872 |
Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions. |
Donovan BT, Chen H, Eek P, Meng Z, Jipa C, Tan S, Bai L, Poirier MG |
Molecular cell |
36996811 |
Mol Cell |
2023 Apr 20 |
https://www.ncbi.nlm.nih.gov/pubmed/36996811 |
Energy Coupling and Stoichiometry of Zn(2+)/H(+) Antiport by the Cation Diffusion Facilitator YiiP. |
Hussein A, Fan S, Lopez-Redondo M, Kenney I, Zhang X, Beckstein O, Stokes DL |
bioRxiv : the preprint server for biology |
36865113 |
bioRxiv |
2023 Jul 31 |
https://www.ncbi.nlm.nih.gov/pubmed/36865113 |
Mechanism of Ca(2+) transport by ferroportin. |
Shen J, Wilbon AS, Zhou M, Pan Y |
eLife |
36648329 |
Elife |
2023 Jan 17 |
https://www.ncbi.nlm.nih.gov/pubmed/36648329 |
A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. |
Podgorski JM, Freeman K, Gosselin S, Huet A, Conway JF, Bird M, Grecco J, Patel S, Jacobs-Sera D, Hatfull G, Gogarten JP, Ravantti J, White SJ |
Structure (London, England : 1993) |
36649709 |
Structure |
2023 Mar 2 |
https://www.ncbi.nlm.nih.gov/pubmed/36649709 |
Structures of the essential efflux pump EfpA from Mycobacterium tuberculosis reveal the mechanisms of substrate transport and small-molecule inhibition. |
Wang S, Wang K, Song K, Li P, Li D, Sun Y, Mei Y, Xu C, Liao M |
Research square |
38260587 |
Res Sq |
2024 Jan 5 |
https://www.ncbi.nlm.nih.gov/pubmed/38260587 |
The structure of full-length AFPK supports the ACP linker in a role that regulates iterative polyketide and fatty acid assembly. |
Schubert HL, Li F, Hill CP, Schmidt EW |
Proceedings of the National Academy of Sciences of the United States of America |
39913209 |
Proc Natl Acad Sci U S A |
2025 Feb 11 |
https://www.ncbi.nlm.nih.gov/pubmed/39913209 |
RNA control of reverse transcription in a diversity-generating retroelement. |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG, Ghosh P |
Nature |
39779855 |
Nature |
2025 Feb |
https://www.ncbi.nlm.nih.gov/pubmed/39779855 |
AI-Based Discovery and CryoEM Structural Elucidation of a K(ATP) Channel Pharmacochaperone. |
ElSheikh A, Driggers CM, Truong HH, Yang Z, Allen J, Henriksen N, Walczewska-Szewc K, Shyng SL |
bioRxiv : the preprint server for biology |
39282384 |
bioRxiv |
2025 Feb 7 |
https://www.ncbi.nlm.nih.gov/pubmed/39282384 |
Anti-immune complex antibodies are elicited during repeated immunization with HIV Env immunogens. |
Brown S, Antanasijevic A, Sewall LM, Garcia DM, Ferguson J, Brouwer PJM, Sanders RW, Ward AB |
Science immunology |
39823319 |
Sci Immunol |
2025 Jan 17 |
https://www.ncbi.nlm.nih.gov/pubmed/39823319 |
Botulinum neurotoxins exploit host digestive proteases to boost their oral toxicity via activating OrfXs/P47. |
Gao L, Nowakowska MB, Selby K, Przykopanski A, Chen B, Krüger M, Douillard FP, Lam KH, Chen P, Huang T, Minton NP, Dorner MB, Dorner BG, Rummel A, Lindström M, Jin R |
Nature structural & molecular biology |
39838108 |
Nat Struct Mol Biol |
2025 May |
https://www.ncbi.nlm.nih.gov/pubmed/39838108 |
Cryo-EM structure of AAV2 Rep68 bound to integration site AAVS1: insights into the mechanism of DNA melting. |
Jaiswal R, Braud B, Hernandez-Ramirez KC, Santosh V, Washington A, Escalante CR |
Nucleic acids research |
39883011 |
Nucleic Acids Res |
2025 Jan 24 |
https://www.ncbi.nlm.nih.gov/pubmed/39883011 |
Cryo-EM analyses unveil details of mechanism and targocil-II mediated inhibition of S. aureus WTA transporter TarGH. |
Li FKK, Peters SC, Worrall LJ, Sun T, Hu J, Vuckovic M, Farha M, Palacios A, Caveney NA, Brown ED, Strynadka NCJ |
Nature communications |
40185711 |
Nat Commun |
2025 Apr 4 |
https://www.ncbi.nlm.nih.gov/pubmed/40185711 |
Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. |
Huang Y, Kumar S, Lee J, Lü W, Du J |
Nature structural & molecular biology |
38773335 |
Nat Struct Mol Biol |
2024 Oct |
https://www.ncbi.nlm.nih.gov/pubmed/38773335 |
Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain. |
Wu W, Kumar P, Brautigam CA, Tso SC, Baniasadi HR, Kober DL, Gilles-Gonzalez MA |
bioRxiv : the preprint server for biology |
39091779 |
bioRxiv |
2024 Jul 24 |
https://www.ncbi.nlm.nih.gov/pubmed/39091779 |
A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion. |
Nguyen QH, Lai CHR, Norris MJ, Ng D, Shah M, Lai CC, Isenman DE, Moraes TF |
bioRxiv : the preprint server for biology |
39484374 |
bioRxiv |
2024 Oct 21 |
https://www.ncbi.nlm.nih.gov/pubmed/39484374 |
Priming antibody responses to the fusion peptide in rhesus macaques. |
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Allen JD, Nogal B, Silva M, Bhiman J, Pauthner M, Irvine DJ, Montefiori D, Crispin M, Burton DR, Silvestri G, Crotty S, Ward AB |
NPJ vaccines |
38997302 |
NPJ Vaccines |
2024 Jul 12 |
https://www.ncbi.nlm.nih.gov/pubmed/38997302 |
High-affinity agonism at the P2X(7) receptor is mediated by three residues outside the orthosteric pocket. |
Oken AC, Lisi NE, Krishnamurthy I, McCarthy AE, Godsey MH, Glasfeld A, Mansoor SE |
Nature communications |
39107314 |
Nat Commun |
2024 Aug 6 |
https://www.ncbi.nlm.nih.gov/pubmed/39107314 |
Structural basis of TFIIIC-dependent RNA Polymerase III transcription initiation. |
Talyzina A, Han Y, Banerjee C, Fishbain S, Reyes A, Vafabakhsh R, He Y |
bioRxiv : the preprint server for biology |
37292922 |
bioRxiv |
2023 May 16 |
https://www.ncbi.nlm.nih.gov/pubmed/37292922 |
30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. |
Srinivas P, Nosrati M, Zelinskaya N, Dey D, Comstock LR, Dunham CM, Conn GL |
Proceedings of the National Academy of Sciences of the United States of America |
37307464 |
Proc Natl Acad Sci U S A |
2023 Jun 20 |
https://www.ncbi.nlm.nih.gov/pubmed/37307464 |
A Suite of Designed Protein Cages Using Machine Learning Algorithms and Protein Fragment-Based Protocols. |
Meador K, Castells-Graells R, Aguirre R, Sawaya MR, Arbing MA, Sherman T, Senarathne C, Yeates TO |
bioRxiv : the preprint server for biology |
37873110 |
bioRxiv |
2023 Oct 9 |
https://www.ncbi.nlm.nih.gov/pubmed/37873110 |
Biophysical basis of tight junction barrier modulation by a pan-claudin-binding molecule. |
Ogbu CP, de Las Alas M, Mandriota AM, Liu X, Kapoor S, Choudhury J, Ruma YN, Goodman MC, Sanders CR, Gonen T, Kossiakoff AA, Duffey ME, Vecchio AJ |
PNAS nexus |
40575703 |
PNAS Nexus |
2025 Jun |
https://www.ncbi.nlm.nih.gov/pubmed/40575703 |
Structure and infection dynamics of mycobacteriophage Bxb1. |
Freeman KG, Mondal S, Macale LS, Podgorski J, White SJ, Silva BH, Ortiz V, Huet A, Perez RJ, Narsico JT, Ho MC, Jacobs-Sera D, Lowary TL, Conway JF, Park D, Hatfull GF |
Cell |
40239650 |
Cell |
2025 May 29 |
https://www.ncbi.nlm.nih.gov/pubmed/40239650 |
Allosteric Inhibition of a Vesicular Glutamate Transporter by an Isoform-Specific Antibody. |
Eriksen J, Li F, Stroud RM, Edwards RH |
Biochemistry |
34319067 |
Biochemistry |
2021 Aug 17 |
https://www.ncbi.nlm.nih.gov/pubmed/34319067 |
Structures of an active type III-A CRISPR effector complex. |
Smith EM, Ferrell S, Tokars VL, Mondragón A |
Structure (London, England : 1993) |
35714601 |
Structure |
2022 Aug 4 |
https://www.ncbi.nlm.nih.gov/pubmed/35714601 |
Selective G protein signaling driven by substance P-neurokinin receptor dynamics. |
Harris JA, Faust B, Gondin AB, Dämgen MA, Suomivuori CM, Veldhuis NA, Cheng Y, Dror RO, Thal DM, Manglik A |
Nature chemical biology |
34711980 |
Nat Chem Biol |
2022 Jan |
https://www.ncbi.nlm.nih.gov/pubmed/34711980 |
Structure and desensitization of AMPA receptor complexes with type II TARP γ5 and GSG1L. |
Klykov O, Gangwar SP, Yelshanskaya MV, Yen L, Sobolevsky AI |
Molecular cell |
34678168 |
Mol Cell |
2021 Dec 2 |
https://www.ncbi.nlm.nih.gov/pubmed/34678168 |
Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. |
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS |
The Journal of experimental medicine |
35297953 |
J Exp Med |
2022 Apr 4 |
https://www.ncbi.nlm.nih.gov/pubmed/35297953 |
Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. |
Li S, Palo MZ, Pintilie G, Zhang X, Su Z, Kappel K, Chiu W, Zhang K, Das R |
Proceedings of the National Academy of Sciences of the United States of America |
36067294 |
Proc Natl Acad Sci U S A |
2022 Sep 13 |
https://www.ncbi.nlm.nih.gov/pubmed/36067294 |
Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. |
Yu Z, Chen J, Takagi E, Wang F, Saha B, Liu X, Joubert LM, Gleason CE, Jin M, Li C, Nowotny C, Agard D, Cheng Y, Pearce D |
The Journal of biological chemistry |
35926713 |
J Biol Chem |
2022 Sep |
https://www.ncbi.nlm.nih.gov/pubmed/35926713 |
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. |
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS |
Nature communications |
37185252 |
Nat Commun |
2023 Apr 25 |
https://www.ncbi.nlm.nih.gov/pubmed/37185252 |
Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. |
Lu J, Fang J, Zhu H, Liang KL, Khudaverdyan N, Song J |
Nucleic acids research |
37941146 |
Nucleic Acids Res |
2023 Dec 11 |
https://www.ncbi.nlm.nih.gov/pubmed/37941146 |
Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy. |
Logan GJ, Mietzsch M, Khandekar N, D'Silva A, Anderson D, Mandwie M, Hsi J, Nelson AR, Chipman P, Jackson J, Schofield P, Christ D, Goodnow CC, Reed JH, Farrar MA, McKenna R, Alexander IE |
Molecular therapy : the journal of the American Society of Gene Therapy |
37012705 |
Mol Ther |
2023 Jul 5 |
https://www.ncbi.nlm.nih.gov/pubmed/37012705 |
Cryo-EM Structure of a Human LECT2 Amyloid Fibril Reveals a Network of Polar Ladders at its Core. |
Richards LS, Flores MD, Zink S, Schibrowsky NA, Sawaya MR, Rodriguez JA |
bioRxiv : the preprint server for biology |
36798409 |
bioRxiv |
2023 Feb 11 |
https://www.ncbi.nlm.nih.gov/pubmed/36798409 |
Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. |
Kretsch RC, Xu L, Zheludev IN, Zhou X, Huang R, Nye G, Li S, Zhang K, Chiu W, Das R |
bioRxiv : the preprint server for biology |
38076883 |
bioRxiv |
2023 Nov 27 |
https://www.ncbi.nlm.nih.gov/pubmed/38076883 |
Structural dynamics of GluK2 kainate receptors in apo and partial agonist bound states. |
Bogdanović N, Segura-Covarrubias G, Zhang L, Tajima N |
Research square |
38076992 |
Res Sq |
2023 Dec 2 |
https://www.ncbi.nlm.nih.gov/pubmed/38076992 |
Biophysical and structural insights into AAV genome ejection. |
Gliwa K, Hull J, Kansol A, Zembruski V, Lakshmanan R, Mietzsch M, Chipman P, Bennett A, McKenna R |
Journal of virology |
39907279 |
J Virol |
2025 Mar 18 |
https://www.ncbi.nlm.nih.gov/pubmed/39907279 |
RAN MODULATES ALLOSTERIC CROSSTALK BETWEEN IMPORTIN β SURFACES. |
Ko YH, Li F, Suinn S, Li J, Hou CD, Lokareddy RK, Cingolani G |
Research square |
40313743 |
Res Sq |
2025 Apr 25 |
https://www.ncbi.nlm.nih.gov/pubmed/40313743 |
Structural basis for L-isoaspartyl-containing protein recognition by the PCMTD1 cullin-RING E3 ubiquitin ligase. |
Pang EZ, Zhao B, Flowers C, Oroudjeva E, Winter JB, Pandey V, Sawaya MR, Wohlschlegel J, Loo JA, Rodriguez JA, Clarke SG |
bioRxiv : the preprint server for biology |
40475564 |
bioRxiv |
2025 May 21 |
https://www.ncbi.nlm.nih.gov/pubmed/40475564 |
Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. |
Rosenberg GM, Abskharon R, Boyer DR, Ge P, Sawaya MR, Eisenberg DS |
PNAS nexus |
38077690 |
PNAS Nexus |
2023 Dec |
https://www.ncbi.nlm.nih.gov/pubmed/38077690 |
Cryo-EM structure of a human LECT2 amyloid fibril reveals a network of polar ladders at its core. |
Richards LS, Flores MD, Zink S, Schibrowsky NA, Sawaya MR, Rodriguez JA |
Structure (London, England : 1993) |
37657439 |
Structure |
2023 Nov 2 |
https://www.ncbi.nlm.nih.gov/pubmed/37657439 |
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. |
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter J, Dror RO, Evers AS, Mukhopadhyay S, Manglik A |
bioRxiv : the preprint server for biology |
37292845 |
bioRxiv |
2023 May 24 |
https://www.ncbi.nlm.nih.gov/pubmed/37292845 |
EMC chaperone-Ca(V) structure reveals an ion channel assembly intermediate. |
Chen Z, Mondal A, Abderemane-Ali F, Jang S, Niranjan S, Montaño JL, Zaro BW, Minor DL Jr |
Nature |
37196677 |
Nature |
2023 Jul |
https://www.ncbi.nlm.nih.gov/pubmed/37196677 |
CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. |
Xu M, Neelands T, Powers AS, Liu Y, Miller SD, Pintilie GD, Bois JD, Dror RO, Chiu W, Maduke M |
eLife |
38345841 |
Elife |
2024 Feb 12 |
https://www.ncbi.nlm.nih.gov/pubmed/38345841 |
Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F(1)-F(o) coupling. |
Sharma S, Luo M, Patel H, Mueller DM, Liao M |
Nature structural & molecular biology |
38316880 |
Nat Struct Mol Biol |
2024 Apr |
https://www.ncbi.nlm.nih.gov/pubmed/38316880 |
Structure and mechanism of the alkane-oxidizing enzyme AlkB. |
Guo X, Zhang J, Han L, Lee J, Williams SC, Forsberg A, Xu Y, Austin RN, Feng L |
Nature communications |
37069165 |
Nat Commun |
2023 Apr 17 |
https://www.ncbi.nlm.nih.gov/pubmed/37069165 |
Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold. |
Fontana P, Dong Y, Pi X, Tong AB, Hecksel CW, Wang L, Fu TM, Bustamante C, Wu H |
Science (New York, N.Y.) |
35679401 |
Science |
2022 Jun 10 |
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Science (New York, N.Y.) |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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bioRxiv |
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Proc Natl Acad Sci U S A |
2024 Mar 5 |
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bioRxiv : the preprint server for biology |
39464091 |
bioRxiv |
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Nature communications |
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Nat Commun |
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Nature communications |
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Nat Commun |
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Nature chemical biology |
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Nat Chem Biol |
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Nature communications |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Nature communications |
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Nat Commun |
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ACS Cent Sci |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Nature communications |
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Nat Commun |
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bioRxiv |
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Cell |
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Nature |
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Nature |
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Science (New York, N.Y.) |
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Science |
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Viruses |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Research square |
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Res Sq |
2024 Feb 21 |
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Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. |
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The Journal of general physiology |
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J Gen Physiol |
2023 Feb 6 |
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Nature |
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Nature |
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Science advances |
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Sci Adv |
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mBio |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Structure of E6AP in complex with HPV16-E6 and p53 reveals a novel ordered domain important for E3 ligase activation. |
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Nature |
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Nature |
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Journal of structural biology |
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J Struct Biol |
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Nature |
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Nature |
2022 Sep |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
2021 Sep |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
2022 Feb |
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Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. |
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Biophys J |
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Nature communications |
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Nat Commun |
2023 Apr 17 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2023 Nov 29 |
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Nature structural & molecular biology |
37653241 |
Nat Struct Mol Biol |
2023 Oct |
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Mobile barrier mechanisms for Na(+)-coupled symport in an MFS sugar transporter. |
Hariharan P, Shi Y, Katsube S, Willibal K, Burrows ND, Mitchell P, Bakhtiiari A, Stanfield S, Pardon E, Kaback HR, Liang R, Steyaert J, Viner R, Guan L |
eLife |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Apr 18 |
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The Structures of Secretory IgA in complex with Streptococcus pyogenes M4 and human CD89 provide insights on mucosal host-pathogen interactions. |
Liu Q, Stadtmueller BM |
bioRxiv : the preprint server for biology |
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bioRxiv |
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Nature |
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Nature |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
2023 Jun |
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Nature |
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Nature |
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The Journal of general physiology |
36633586 |
J Gen Physiol |
2023 Mar 6 |
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Science advances |
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Sci Adv |
2022 Dec 2 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Cell |
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Cell |
2025 Feb 6 |
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The Structural, Biophysical, and Antigenic Characterization of the Goose Parvovirus Capsid. |
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Microorganisms |
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Microorganisms |
2025 Jan 3 |
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Communications biology |
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Commun Biol |
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Nature microbiology |
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Nat Microbiol |
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bioRxiv : the preprint server for biology |
38915634 |
bioRxiv |
2024 Jun 11 |
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SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions. |
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Nature communications |
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Nat Commun |
2023 Oct 23 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Cell host & microbe |
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Cell Host Microbe |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Structure of the human cone photoreceptor cyclic nucleotide-gated channel. |
Zheng X, Hu Z, Li H, Yang J |
Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Trends in biochemical sciences |
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Trends Biochem Sci |
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Cell |
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Nat Struct Mol Biol |
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Proc Natl Acad Sci U S A |
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Mol Cell |
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Communications biology |
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Commun Biol |
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Nature |
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Nature |
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bioRxiv |
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Nature communications |
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Nat Commun |
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Nature communications |
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Acta crystallographica. Section F, Structural biology communications |
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Acta Crystallogr F Struct Biol Commun |
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bioRxiv |
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Cell reports |
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Nucleic Acids Res |
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bioRxiv : the preprint server for biology |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Nature communications |
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Nat Commun |
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Cell Rep |
2021 Jan 12 |
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International journal of molecular sciences |
33440717 |
Int J Mol Sci |
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Scientific reports |
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Sci Rep |
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Science (New York, N.Y.) |
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Science |
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bioRxiv |
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bioRxiv |
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Proc Natl Acad Sci U S A |
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Acta Crystallogr C Struct Chem |
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Nature communications |
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Two Forms of Thick Filament in the Flight Muscle of Drosophila melanogaster. |
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International journal of molecular sciences |
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Int J Mol Sci |
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Proceedings of the National Academy of Sciences of the United States of America |
40327693 |
Proc Natl Acad Sci U S A |
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Research square |
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Res Sq |
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Nature |
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Nature |
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bioRxiv : the preprint server for biology |
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Research square |
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Res Sq |
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Huang J, Tong L |
Nature communications |
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Nat Commun |
2025 Apr 7 |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Nat Struct Mol Biol |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Nature |
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Nature |
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Cell |
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Cell |
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Structure |
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Frontiers in molecular biosciences |
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Front Mol Biosci |
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bioRxiv |
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Acta crystallographica. Section C, Structural chemistry |
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Acta Crystallogr C Struct Chem |
2024 Jun 1 |
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Conformational switching and flexibility in cobalamin-dependent methionine synthase studied by small-angle X-ray scattering and cryoelectron microscopy. |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Current opinion in structural biology |
37392555 |
Curr Opin Struct Biol |
2023 Aug |
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High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217. |
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Nature communications |
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Nat Commun |
2023 Jul 8 |
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Structures, functions and adaptations of the human LINE-1 ORF2 protein. |
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Nature |
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Nature |
2024 Feb |
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Structures of the promoter-bound respiratory syncytial virus polymerase. |
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Nature |
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Nature |
2024 Jan |
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Product analog binding identifies the copper active site of particulate methane monooxygenase. |
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Nature catalysis |
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Nat Catal |
2023 Dec |
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Molecular Basis of Human Trace Amine-Associated Receptor 1 Activation. |
Zilberg G, Parpounas AK, Warren AL, Yang S, Wacker D |
bioRxiv : the preprint server for biology |
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bioRxiv |
2023 Sep 7 |
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Science immunology |
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Sci Immunol |
2025 Jan 24 |
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bioRxiv |
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Cell reports |
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Cell Rep |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Molecular cell |
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Mol Cell |
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Molecular cell |
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Mol Cell |
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Immunity |
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Immunity |
2021 Sep 14 |
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Cell host & microbe |
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Cell Host Microbe |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2021 Mar 23 |
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Structural basis for substrate selection by the SARS-CoV-2 replicase. |
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Nature |
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Nature |
2023 Feb |
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Improved mammalian retromer cryo-EM structures reveal a new assembly interface. |
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The Journal of biological chemistry |
36174678 |
J Biol Chem |
2022 Nov |
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Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel. |
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Nature communications |
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Nat Commun |
2023 Jul 18 |
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Cat1 forms filament networks to degrade NAD(+) during the type III CRISPR-Cas antiviral response. |
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Science (New York, N.Y.) |
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Science |
2025 Jun 12 |
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The pentameric chloride channel BEST1 is activated by extracellular GABA. |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Nature |
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Nature |
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Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses. |
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bioRxiv : the preprint server for biology |
33594359 |
bioRxiv |
2021 Jul 9 |
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Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis. |
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ACS omega |
33458462 |
ACS Omega |
2021 Jan 12 |
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Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis. |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2020 Jun 17 |
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Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. |
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Cell |
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Cell |
2021 May 27 |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2020 May 12 |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Oct 12 |
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The CRISPR-associated adenosine deaminase Cad1 converts ATP to ITP to provide antiviral immunity. |
Baca CF, Majumder P, Hickling JH, Ye L, Teplova M, Brady SF, Patel DJ, Marraffini LA |
Cell |
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Cell |
2024 Dec 12 |
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A structure-based mechanism for initiation of AP-3 coated vesicle formation. |
Begley M, Aragon M, Baker RW |
bioRxiv : the preprint server for biology |
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bioRxiv |
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Bowman SEJ, Byrnes J, Russi S, Zimanyi CM |
Acta crystallographica. Section F, Structural biology communications |
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Acta Crystallogr F Struct Biol Commun |
2024 Aug 1 |
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Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. |
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris ME |
Nature communications |
36045135 |
Nat Commun |
2022 Aug 31 |
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Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage. |
Finkelstein MT, Parker Miller E, Erdman MC, Fera D |
Frontiers in immunology |
36225920 |
Front Immunol |
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Molecular basis of human trace amine-associated receptor 1 activation. |
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Nature communications |
38168118 |
Nat Commun |
2024 Jan 2 |
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CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization. |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 May 13 |
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Nature structural & molecular biology |
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Nat Struct Mol Biol |
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Structures of the holo CRISPR RNA-guided transposon integration complex. |
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Nature |
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Nature |
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Structural basis of ferroportin inhibition by minihepcidin PR73. |
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PLoS biology |
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PLoS Biol |
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Fabrication of membrane proteins in the form of native cell membrane nanoparticles using novel membrane active polymers. |
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Nanoscale advances |
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Nanoscale Adv |
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Acta crystallographica. Section F, Structural biology communications |
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Acta Crystallogr F Struct Biol Commun |
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Miffi: Improving the accuracy of CNN-based cryo-EM micrograph filtering with fine-tuning and Fourier space information. |
Xu D, Ando N |
bioRxiv : the preprint server for biology |
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bioRxiv |
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Nature communications |
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Nat Commun |
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Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination. |
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bioRxiv : the preprint server for biology |
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bioRxiv |
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Blueprinting extendable nanomaterials with standardized protein blocks. |
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Nature |
38480887 |
Nature |
2024 Mar |
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Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT(1e)R and 5-HT(1F)R. |
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Science advances |
38630816 |
Sci Adv |
2024 Apr 19 |
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Structural insights into the diversity and DNA cleavage mechanism of Fanzor. |
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Cell |
39208796 |
Cell |
2024 Sep 19 |
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DISTANT RIBOSE 2'-O-METHYLATION OF 23S rRNA HELIX 69 PRE-ORDERS THE CAPREOMYCIN DRUG BINDING POCKET AT THE RIBOSOME SUBUNIT INTERFACE. |
Nandi S, Dey D, Srinivas P, Dunham CM, Conn GL |
bioRxiv : the preprint server for biology |
39574593 |
bioRxiv |
2024 Nov 5 |
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Mechanism of Nucleotide-Dependent Allosteric Regulation in Escherichia coli Aspartate Transcarbamoylase. |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Nov 20 |
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Conformational landscapes of a class I ribonucleotide reductase complex during turnover reveal intrinsic dynamics and asymmetry. |
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Nature communications |
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Nat Commun |
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Quantitative Spatial Analysis of Chromatin Biomolecular Condensates using Cryo-Electron Tomography. |
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bioRxiv : the preprint server for biology |
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bioRxiv |
2024 Dec 31 |
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A structure-based mechanism for initiation of AP-3 coated vesicle formation. |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
2024 Dec 24 |
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Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies. |
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Science advances |
40267182 |
Sci Adv |
2025 Apr 25 |
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Proceedings of the National Academy of Sciences of the United States of America |
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Proc Natl Acad Sci U S A |
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Understanding Pitfalls and Opportunities of Applying Heuristic Evaluation Methods to VR Training Systems: An Empirical Study. |
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International journal of human-computer interaction |
38863735 |
Int J Hum Comput Interact |
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ManiLoco: A VR-Based Locomotion Method for Concurrent Object Manipulation. |
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Proceedings of the ACM on computer graphics and interactive techniques |
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Proc ACM Comput Graph Interact Tech |
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IEEE transactions on circuits and systems for video technology : a publication of the Circuits and Systems Society |
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IEEE Trans Circuits Syst Video Technol |
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Development of CryoVR, a virtual reality training system for hands-on cryoEM operations. |
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Acta crystallographica. Section D, Structural biology |
35775989 |
Acta Crystallogr D Struct Biol |
2022 Jul 1 |
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Computational Methods for Single-Particle Electron Cryomicroscopy. |
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Annual review of biomedical data science |
34485850 |
Annu Rev Biomed Data Sci |
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Protocol to study CCT-mediated folding of Gβ(5) by single-particle cryo-EM. |
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STAR protocols |
38848218 |
STAR Protoc |
2024 Jun 21 |
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Lysate-to-grid: Rapid Isolation of Native Complexes from Budding Yeast for Cryo-EM Imaging. |
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Bio-protocol |
36789166 |
Bio Protoc |
2023 Jan 20 |
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