Structural Biology
Structural Biology
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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
| Title | Authors | Journal | PubMedID | Publication Date |
|---|---|---|---|---|
| Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser. | Arnlund, David; Johansson, Linda C; Wickstrand, Cecilia; Barty, Anton; Williams, Garth J; Malmerberg, Erik; Davidsson, Jan; Milathianaki, Despina; DePonte, Daniel P; Shoeman, Robert L; Wang, Dingjie; James, Daniel; Katona, Gergely; Westenhoff, Sebastian; | Nature methods | 25108686 | 2014 Sep |
| Tetra detector analysis of membrane proteins. | Miercke, Larry J W; Robbins, Rebecca A; Stroud, Robert M | Current protocols in protein science / editorial board, John E. Coligan ... [et al.] | 25081744 | 2014 |
| A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR). | Hildebrandt, Ellen; Zhang, Qinghai; Cant, Natasha; Ding, Haitao; Dai, Qun; Peng, Lingling; Fu, Yu; DeLucas, Lawrence J; Ford, Robert; Kappes, John C; Urbatsch, Ina L | Biochimica et biophysica acta | 25065669 | 2014 Jul 24 |
| Renaturing membrane proteins in the lipid cubic phase, a nanoporous membrane mimetic. | Li, Dianfan; Caffrey, Martin | Scientific reports | 25055873 | 2014 |
| A new broadband homonuclear mixing pulse for NMR with low applied power. | Coote, Paul; Leigh, Kendra E; Yu, Tsyr-Yan; Khaneja, Navin; Wagner, Gerhard; Arthanari, Haribabu | The Journal of chemical physics | 25028012 | 2014 Jul 14 |
| Cellular solid-state NMR investigation of a membrane protein using dynamic nuclear polarization. | Yamamoto, Kazutoshi; Caporini, Marc A; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy | Biochimica et biophysica acta | 25017802 | 2014 Jul 11 |
| NMR Polypeptide Backbone Conformation of the E.ýýcoli Outer Membrane Protein W. | Horst, Reto; Stanczak, Pawel; Wuthrich, Kurt | Structure (London, England : 1993) | 25017731 | 2014 Aug 5 |
| Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination. | Boland, Coilin; Li, Dianfan; Shah, Syed Tasadaque Ali; Haberstock, Stefan; Dotsch, Volker; Bernhard, Frank; Caffrey, Martin | Cellular and molecular life sciences : CMLS | 25012698 | 2014 Jul 11 |
| Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. | Wang, Chong; Wu, Huixian; Evron, Tama; Vardy, Eyal; Han, Gye Won; Huang, Xi-Ping; Hufeisen, Sandy J; Mangano, Thomas J; Urban, Dan J; Katritch, Vsevolod; Cherezov, Vadim; Caron, Marc G; Roth, Bryan L; Stevens, Raymond C | Nature communications | 25008467 | 2014 |
| 'Hit and run' serial femtosecond crystallography of a membrane kinase in the lipid cubic phase. | Caffrey, Martin; Li, Dianfan; Howe, Nicole; Shah, Syed T A | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 24914170 | 2014 Jul 17 |
| 7 A resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source. | Pedrini, Bill; Tsai, Ching-Ju; Capitani, Guido; Padeste, Celestino; Hunter, Mark S; Zatsepin, Nadia A; Barty, Anton; Benner, W Henry; Boutet, Sebastien; Feld, Geoffrey K; Hau-Riege, Stefan P; Kirian, Richard A; Kupitz, Christopher; Messerschmitt, Marc; Og | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 24914166 | 2014 Jul 17 |
| Microcrystallization techniques for serial femtosecond crystallography using photosystem II from Thermosynechococcus elongatus as a model system. | Kupitz, Christopher; Grotjohann, Ingo; Conrad, Chelsie E; Roy-Chowdhury, Shatabdi; Fromme, Raimund; Fromme, Petra | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 24914149 | 2014 Jul 17 |
| Femtosecond crystallography of membrane proteins in the lipidic cubic phase. | Liu, Wei; Wacker, Daniel; Wang, Chong; Abola, Enrique; Cherezov, Vadim | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 24914147 | 2014 Jul 17 |
| Real-time conformational changes in LacY. | Smirnova, Irina; Kasho, Vladimir; Kaback, H Ronald | Proceedings of the National Academy of Sciences of the United States of America | 24872451 | 2014 Jun 10 |
| The Use of Amphipols for NMR Structural Characterization of 7-TM Proteins. | Elter, Shantha; Raschle, Thomas; Arens, Sabine; Viegas, Aldino; Gelev, Vladimir; Etzkorn, Manuel; Wagner, Gerhard | The Journal of membrane biology | 24858950 | 2014 May 25 |
| Probing the transmembrane structure and dynamics of microsomal NADPH-cytochrome P450 oxidoreductase by solid-state NMR. | Huang, Rui; Yamamoto, Kazutoshi; Zhang, Meng; Popovych, Nataliya; Hung, Ivan; Im, Sang-Choul; Gan, Zhehong; Waskell, Lucy; Ramamoorthy, Ayyalusamy | Biophysical journal | 24853741 | 2014 May 20 |
| Applications of the second virial coefficient: protein crystallization and solubility. | Wilson, William W; Delucas, Lawrence J | Acta crystallographica. Section F, Structural biology communications | 24817708 | 2014 May |
| 3D (15)N/(15)N/(1)H chemical shift correlation experiment utilizing an RFDR-based (1)H/(1)H mixing period at 100kHz MAS. | Nishiyama, Yusuke; Malon, Michal; Ishii, Yuji; Ramamoorthy, Ayyalusamy | Journal of magnetic resonance (San Diego, Calif. : 1997) | 24801998 | 2014 Apr 19 |
| Performance of RINEPT is amplified by dipolar couplings under ultrafast MAS conditions. | Zhang, Rongchun; Ramamoorthy, Ayyalusamy | Journal of magnetic resonance (San Diego, Calif. : 1997) | 24792960 | 2014 Jun |
| Finite-pulse radio frequency driven recoupling with phase cycling for 2D (1)H/(1)H correlation at ultrafast MAS frequencies. | Nishiyama, Yusuke; Zhang, Rongchun; Ramamoorthy, Ayyalusamy | Journal of magnetic resonance (San Diego, Calif. : 1997) | 24713171 | 2014 Jun |
| Substrate-induced changes in the structural properties of LacY. | Serdiuk, Tetiana; Madej, M Gregor; Sugihara, Junichi; Kawamura, Shiho; Mari, Stefania A; Kaback, H Ronald; Muller, Daniel J | Proceedings of the National Academy of Sciences of the United States of America | 24711390 | 2014 Apr 22 |
| An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3. | Schifano, Jason M; Vvedenskaya, Irina O; Knoblauch, Jared G; Ouyang, Ming; Nickels, Bryce E; Woychik, Nancy A | Nature communications | 24709835 | 2014 |
| Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazines. | Schurig-Briccio, Lici A; Yano, Takahiro; Rubin, Harvey; Gennis, Robert B | Biochimica et biophysica acta | 24709059 | 2014 Jul |
| Engineering cells to improve protein expression. | Xiao, Su; Shiloach, Joseph; Betenbaugh, Michael J | Current opinion in structural biology | 24704806 | 2014 Jun |
| Solution-NMR characterization of outer-membrane protein A from E. coli in lipid bilayer nanodiscs and detergent micelles. | Susac, Lukas; Horst, Reto; Wuthrich, Kurt | Chembiochem : a European journal of chemical biology | 24692152 | 2014 May 5 |
| Proton-detected 2D radio frequency driven recoupling solid-state NMR studies on micelle-associated cytochrome-b5. | Pandey, Manoj Kumar; Vivekanandan, Subramanian; Yamamoto, Kazutoshi; Im, Sangchoul; Waskell, Lucy; Ramamoorthy, Ayyalusamy | Journal of magnetic resonance (San Diego, Calif. : 1997) | 24657390 | 2014 May |
| Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments. | Kalyoncu, Sibel; Hyun, Jeongmin; Pai, Jennifer C; Johnson, Jennifer L; Entzminger, Kevin; Jain, Avni; Heaner Jr, David P; Morales, Ivan A; Truskett, Thomas M; Maynard, Jennifer A; Lieberman, Raquel L | Proteins | 24615866 | 2014 Feb 26 |
| Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. | Monk, Brian C; Tomasiak, Thomas M; Keniya, Mikhail V; Huschmann, Franziska U; Tyndall, Joel D A; O'Connell 3rd, Joseph D; Cannon, Richard D; McDonald, Jeffrey G; Rodriguez, Andrew; Finer-Moore, Janet S; Stroud, Robert M | Proceedings of the National Academy of Sciences of the United States of America | 24613931 | 2014 Mar 11 |
| Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. | Wu, Huixian; Wang, Chong; Gregory, Karen J; Han, Gye Won; Cho, Hyekyung P; Xia, Yan; Niswender, Colleen M; Katritch, Vsevolod; Meiler, Jens; Cherezov, Vadim; Conn, P Jeffrey; Stevens, Raymond C | Science (New York, N.Y.) | 24603153 | 2014 Apr 4 |
| A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in G*i1. | Thaker, Tarjani M; Sarwar, Maruf; Preininger, Anita M; Hamm, Heidi E; Iverson, T M | The Journal of biological chemistry | 24596087 | 2014 Apr 18 |
| Direct phasing in femtosecond nanocrystallography. I. Diffraction characteristics. | Chen, Joe P J; Spence, John C H; Millane, Rick P | Acta crystallographica. Section A, Foundations and advances | 24572315 | 2014 Mar |
| Functional architecture of MFS D-glucose transporters. | Madej, M Gregor; Sun, Linfeng; Yan, Nieng; Kaback, H Ronald | Proceedings of the National Academy of Sciences of the United States of America | 24550316 | 2014 Feb 18 |
| Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. | Weierstall, Uwe; James, Daniel; Wang, Chong; White, Thomas A; Wang, Dingjie; Liu, Wei; Spence, John C H; Bruce Doak, R; Nelson, Garrett; Fromme, Petra; Fromme, Raimund; Grotjohann, Ingo; Kupitz, Christopher; Zatsepin, Nadia A; Liu, Haiguang; Basu, Shibom; | Nature communications | 24525480 | 2014 Feb 14 |
| 23S rRNA as an a-Maz-ing new bacterial toxin target. | Schifano, Jason M; Woychik, Nancy A | RNA biology | 24525465 | 2014 Feb |
| Drug screening strategy for human membrane proteins: from NMR protein backbone structure to in silica- and NMR-screened hits. | Lindert, Steffen; Maslennikov, Innokentiy; Chiu, Ellis J C; Pierce, Levi C; McCammon, J Andrew; Choe, Senyon | Biochemical and biophysical research communications | 24525125 | 2014 Mar 21 |
| Galactoside-binding site in LacY. | Jiang, Xiaoxu; Villafuerte, Maria Katerina R; Andersson, Magnus; White, Stephen H; Kaback, H Ronald | Biochemistry | 24520888 | 2014 Mar 11 |
| Protein and lipid interactions driving molecular mechanisms of in meso crystallization. | Johner, Niklaus; Mondal, Sayan; Morra, Giulia; Caffrey, Martin; Weinstein, Harel; Khelashvili, George | Journal of the American Chemical Society | 24494670 | 2014 Feb 26 |
| Dynafold: a dynamic programming approach to protein backbone structure determination from minimal sets of Residual Dipolar Couplings. | Mukhopadhyay, Rishi; Irausquin, Stephanie; Schmidt, Christopher; Valafar, Homayoun | Journal of bioinformatics and computational biology | 24467760 | 2014 Feb |
| Bicelles exhibiting magnetic alignment for a broader range of temperatures: a solid-state NMR study. | Yamamoto, Kazutoshi; Pearcy, Paige; Ramamoorthy, Ayyalusamy | Langmuir : the ACS journal of surfaces and colloids | 24460179 | 2014 Feb 18 |
| Structure of sugar-bound LacY. | Kumar, Hemant; Kasho, Vladimir; Smirnova, Irina; Finer-Moore, Janet S; Kaback, H Ronald; Stroud, Robert M | Proceedings of the National Academy of Sciences of the United States of America | 24453216 | 2014 Feb 4 |
| Doc toxin is a kinase that inactivates elongation factor Tu. | Cruz, Jonathan W; Rothenbacher, Francesca P; Maehigashi, Tatsuya; Lane, William S; Dunham, Christine M; Woychik, Nancy A | The Journal of biological chemistry | 24448800 | 2014 Mar 14 |
| Back to the future: recombinant polyclonal antibody therapeutics. | Wang, Xian-Zhe; Coljee, Vincent W; Maynard, Jennifer A | Current opinion in chemical engineering | 24443710 | 2013 Nov |
| Molecular control of ýý-opioid receptor signalling. | Fenalti, Gustavo; Giguere, Patrick M; Katritch, Vsevolod; Huang, Xi-Ping; Thompson, Aaron A; Cherezov, Vadim; Roth, Bryan L; Stevens, Raymond C | Nature | 24413399 | 2014 Jan 12 |
| Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease. | Lee, Sanghyun; Zheng, Xueyun; Krishnamoorthy, Janarthanan; Savelieff, Masha G; Park, Hyun Min; Brender, Jeffrey R; Kim, Jin Hoon; Derrick, Jeffrey S; Kochi, Akiko; Lee, Hyuck Jin; Kim, Cheal; Ramamoorthy, Ayyalusamy; Bowers, Michael T; Lim, Mi Hee | Journal of the American Chemical Society | 24397771 | 2014 Jan 8 |
| Modulation of raft domains in a lipid bilayer by boundary-active curcumin. | Tsukamoto, Manami; Kuroda, Kenichi; Ramamoorthy, Ayyalusamy; Yasuhara, Kazuma | Chemical communications (Cambridge, England) | 24396862 | 2014 Apr 4 |
| Structure-based mechanism for Na(+)/melibiose symport by MelB. | Ethayathulla, Abdul S; Yousef, Mohammad S; Amin, Anowarul; Leblanc, Gerard; Kaback, H Ronald; Guan, Lan | Nature communications | 24389923 | 2014 |
| Protein structural ensembles are revealed by redefining X-ray electron density noise. | Lang, P Therese; Holton, James M; Fraser, James S; Alber, Tom | Proceedings of the National Academy of Sciences of the United States of America | 24363322 | 2014 Jan 7 |
| Serial femtosecond crystallography of G protein-coupled receptors. | Liu, Wei; Wacker, Daniel; Gati, Cornelius; Han, Gye Won; James, Daniel; Wang, Dingjie; Nelson, Garrett; Weierstall, Uwe; Katritch, Vsevolod; Barty, Anton; Zatsepin, Nadia A; Li, Dianfan; Messerschmidt, Marc; Boutet, Sebastien; Williams, Garth J; Koglin, J | Science (New York, N.Y.) | 24357322 | 2013 Dec 20 |
| Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels. | Zhao, Jun; Hu, Rundong; Sciacca, Michele F M; Brender, Jeffrey R; Chen, Hong; Ramamoorthy, Ayyalusamy; Zheng, Jie | Physical chemistry chemical physics : PCCP | 24352606 | 2014 Jan 15 |
| Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography. | Johansson, Linda C; Arnlund, David; Katona, Gergely; White, Thomas A; Barty, Anton; DePonte, Daniel P; Shoeman, Robert L; Wickstrand, Cecilia; Sharma, Amit; Williams, Garth J; Aquila, Andrew; Bogan, Michael J; Caleman, Carl; Davidsson, Jan; Doak, R Bruce; | Nature communications | 24352554 | 2013 |
| Hydrophobic variations of N-oxide amphiphiles for membrane protein manipulation: importance of non-hydrocarbon groups in the hydrophobic portion. | Chae, Pil Seok; Sadaf, Aiman; Gellman, Samuel H | Chemistry, an Asian journal | 24347070 | 2014 Jan |
| A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-* implicated in Alzheimer's disease. | Savelieff, Masha G; Liu, Yuzhong; Senthamarai, Russell R P; Korshavn, Kyle J; Lee, Hyuck Jin; Ramamoorthy, Ayyalusamy; Lim, Mi Hee | Chemical communications (Cambridge, England) | 24326305 | 2013 Dec 10 |
| Predicting the X-ray lifetime of protein crystals. | Zeldin, Oliver B; Brockhauser, Sandor; Bremridge, John; Holton, James M; Garman, Elspeth F | Proceedings of the National Academy of Sciences of the United States of America | 24297937 | 2013 Dec 17 |
| Insights into Atomic-Level Interaction between Mefenamic Acid and Eudragit EPO in a Supersaturated Solution by High-Resolution Magic-Angle Spinning NMR Spectroscopy. | Higashi, Kenjirou; Yamamoto, Kazutoshi; Pandey, Manoj Kumar; Mroue, Kamal H; Moribe, Kunikazu; Yamamoto, Keiji; Ramamoorthy, Ayyalusamy | Molecular pharmaceutics | 24283196 | 2014 Jan 6 |
| Using macromolecular-crystallography beamline and microfluidic platform for small-angle diffraction studies of lipidic matrices for membrane-protein crystallization. | Kondrashkina, E; Khvostichenko, D S; Perry, S L; Von Osinski, J; Kenis, P J A; Brister, K | Journal of physics. Conference series | 24260038 | 2013 |
| Evolutionary mix-and-match with MFS transporters II. | Madej, M Gregor; Kaback, H Ronald | Proceedings of the National Academy of Sciences of the United States of America | 24259711 | 2013 Dec 10 |
| Shortening spin-lattice relaxation using a copper-chelated lipid at low-temperatures - A magic angle spinning solid-state NMR study on a membrane-bound protein. | Yamamoto, Kazutoshi; Caporini, Marc A; Im, Sangchoul; Waskell, Lucy; Ramamoorthy, Ayyalusamy | Journal of magnetic resonance (San Diego, Calif. : 1997) | 24246881 | 2013 Dec |
| High-resolution NMR reveals secondary structure and folding of amino acid transporter from outer chloroplast membrane. | Zook, James D; Molugu, Trivikram R; Jacobsen, Neil E; Lin, Guangxin; Soll, Jurgen; Cherry, Brian R; Brown, Michael F; Fromme, Petra | PloS one | 24205117 | 2013 |
| Crystallization of the large membrane protein complex photosystem I in a microfluidic channel. | Abdallah, Bahige G; Kupitz, Christopher; Fromme, Petra; Ros, Alexandra | ACS nano | 24191698 | 2013 Dec 23 |
| Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter. | Pak, John Edward; Ekende, Elisabeth Ngonlong; Kifle, Efrem G; O'Connell 3rd, Joseph Daniel; De Angelis, Fabien; Tessema, Meseret B; Derfoufi, Kheiro-Mouna; Robles-Colmenares, Yaneth; Robbins, Rebecca A; Goormaghtigh, Erik; Vandenbussche, Guy; Stroud, Robe | Proceedings of the National Academy of Sciences of the United States of America | 24173033 | 2013 Nov 12 |
| Novel tripod amphiphiles for membrane protein analysis. | Chae, Pil Seok; Kruse, Andrew C; Gotfryd, Kamil; Rana, Rohini R; Cho, Kyung Ho; Rasmussen, Soren G F; Bae, Hyoung Eun; Chandra, Richa; Gether, Ulrik; Guan, Lan; Kobilka, Brian K; Loland, Claus J; Byrne, Bernadette; Gellman, Samuel H | Chemistry (Weinheim an der Bergstrasse, Germany) | 24123610 | 2013 Nov 11 |
| Cytochrome-P450-cytochrome-b5 interaction in a membrane environment changes 15N chemical shift anisotropy tensors. | Pandey, Manoj Kumar; Vivekanandan, Subramanian; Ahuja, Shivani; Huang, Rui; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy | The journal of physical chemistry. B | 24107224 | 2013 Nov 7 |
| (1)H, (13)C and (15)N resonance assignments for the full-length mammalian cytochrome b5 in a membrane environment. | Vivekanandan, Subramanian; Ahuja, Shivani; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy | Biomolecular NMR assignments | 24105099 | 2013 Oct 9 |
| Impact of histidine residues on the transmembrane helices of viroporins. | Wang, Yan; Park, Sang Ho; Tian, Ye; Opella, Stanley J | Molecular membrane biology | 24102567 | 2013 Nov |
| Radiation damage in protein serial femtosecond crystallography using an x-ray free-electron laser. | Lomb, Lukas; Barends, Thomas R M; Kassemeyer, Stephan; Aquila, Andrew; Epp, Sascha W; Erk, Benjamin; Foucar, Lutz; Hartmann, Robert; Rudek, Benedikt; Rolles, Daniel; Rudenko, Artem; Shoeman, Robert L; Andreasson, Jakob; Bajt, Sasa; Barthelmess, Miriam; Ba | Physical review. B, Condensed matter and materials physics | 24089594 | 2011 Dec 1 |
| Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. | Barty, Anton; Caleman, Carl; Aquila, Andrew; Timneanu, Nicusor; Lomb, Lukas; White, Thomas A; Andreasson, Jakob; Arnlund, David; Bajt, Sasa; Barends, Thomas R M; Barthelmess, Miriam; Bogan, Michael J; Bostedt, Christoph; Bozek, John D; Coffee, Ryan; Coppo | Nature photonics | 24078834 | 2012 |
| Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation. | Chae, Pil Seok; Cho, Kyung Ho; Wander, Marc J; Bae, Hyoung Eun; Gellman, Samuel H; Laible, Philip D | Biochimica et biophysica acta | 24064323 | 2014 Jan |
| The N-Terminal Sequence of Tyrosine Hydroxylase Is a Conformationally Versatile Motif That Binds 14-3-3 Proteins and Membranes. | Skjevik, Age Aleksander; Mileni, Mauro; Baumann, Anne; Halskau, Oyvind; Teigen, Knut; Stevens, Raymond C; Martinez, Aurora | Journal of molecular biology | 24055376 | 2013 Sep 17 |
| Membrane protein structure determination in membrana. | Ding, Yi; Yao, Yong; Marassi, Francesca M | Accounts of chemical research | 24041243 | 2013 Sep 17 |
| Dielectrophoretic sorting of membrane protein nanocrystals. | Abdallah, Bahige G; Chao, Tzu-Chiao; Kupitz, Christopher; Fromme, Petra; Ros, Alexandra | ACS nano | 24004002 | 2013 Oct 22 |
| Optimizing E. coli-based membrane protein production using Lemo21(DE3) and GFP-fusions. | Hjelm, Anna; Schlegel, Susan; Baumgarten, Thomas; Klepsch, Mirjam; Wickstrom, David; Drew, David; de Gier, Jan-Willem | Methods in molecular biology (Clifton, N.J.) | 23996190 | 2013 |
| Probing the transmembrane structure and topology of microsomal cytochrome-p450 by solid-state NMR on temperature-resistant bicelles. | Yamamoto, Kazutoshi; Gildenberg, Melissa; Ahuja, Shivani; Im, Sang-Choul; Pearcy, Paige; Waskell, Lucy; Ramamoorthy, Ayyalusamy | Scientific reports | 23989972 | 2013 Aug 30 |
| Dynamic interaction between membrane-bound full-length cytochrome P450 and cytochrome b5 observed by solid-state NMR spectroscopy. | Yamamoto, Kazutoshi; Durr, Ulrich H N; Xu, Jiadi; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy | Scientific reports | 23985776 | 2013 |
| Membrane protein structure determination: back to the membrane. | Yao, Yong; Ding, Yi; Tian, Ye; Opella, Stanley J; Marassi, Francesca M | Methods in molecular biology (Clifton, N.J.) | 23975776 | 2013 |
| Measuring transmembrane helix interaction strengths in lipid bilayers using steric trapping. | Hong, Heedeok; Chang, Yu-Chu; Bowie, James U | Methods in molecular biology (Clifton, N.J.) | 23975771 | 2013 |
| Host Lipid and Temperature as Important Screening Variables for Crystallizing Integral Membrane Proteins in Lipidic Mesophases. Trials with Diacylglycerol Kinase. | Li, Dianfan; Shah, Syed T A; Caffrey, Martin | Crystal growth & design | 23956688 | 2013 Jul 3 |
| *ýýý-adrenergic receptor activation by agonists studied with ýýýýýF NMR spectroscopy. | Horst, Reto; Liu, Jeffrey J; Stevens, Raymond C; Wuthrich, Kurt | Angewandte Chemie (International ed. in English) | 23956158 | 2013 Oct 4 |
| Fluorine-19 NMR of integral membrane proteins illustrated with studies of GPCRs. | Didenko, Tatiana; Liu, Jeffrey J; Horst, Reto; Stevens, Raymond C; Wuthrich, Kurt | Current opinion in structural biology | 23932201 | 2013 Oct |
| YidC protein, a molecular chaperone for LacY protein folding via the SecYEG protein machinery. | Zhu, Lu; Kaback, H Ronald; Dalbey, Ross E | The Journal of biological chemistry | 23928306 | 2013 Sep 27 |
| In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2-x)/ZnS Core/Shell Quantum Dots. | Panthani, Matthew G; Khan, Tarik A; Reid, Dariya K; Hellebusch, Daniel J; Rasch, Michael R; Maynard, Jennifer A; Korgel, Brian A | Nano letters | 23915166 | 2013 Aug 9 |
| The silent codon change I507-ATC->ATT contributes to the severity of the ýýF508 CFTR channel dysfunction. | Lazrak, Ahmed; Fu, Lianwu; Bali, Vedrana; Bartoszewski, Rafal; Rab, Andras; Havasi, Viktoria; Keiles, Steve; Kappes, John; Kumar, Ranjit; Lefkowitz, Elliot; Sorscher, Eric J; Matalon, Sadis; Collawn, James F; Bebok, Zsuzsanna | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 23907436 | 2013 Nov |
| Structure of the human glucagon class B G-protein-coupled receptor. | Siu, Fai Yiu; He, Min; de Graaf, Chris; Han, Gye Won; Yang, Dehua; Zhang, Zhiyun; Zhou, Caihong; Xu, Qingping; Wacker, Daniel; Joseph, Jeremiah S; Liu, Wei; Lau, Jesper; Cherezov, Vadim; Katritch, Vsevolod; Wang, Ming-Wei; Stevens, Raymond C | Nature | 23863937 | 2013 Jul 25 |
| The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry. | Jurgens, Maike C; Voros, Judit; Rautureau, Gilles J P; Shepherd, Dale A; Pye, Valerie E; Muldoon, Jimmy; Johnson, Christopher M; Ashcroft, Alison E; Freund, Stefan M V; Ferguson, Neil | Nature chemical biology | 23851574 | 2013 Sep |
| Three-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in 1,2-Dihexanoyl-sn-glycero-3-phosphocholine by Solution Nuclear Magnetic Resonance. | Cook, Gabriel A; Dawson, Lindsay A; Tian, Ye; Opella, Stanley J | Biochemistry | 23841474 | 2013 Jul 24 |
| Engineered nanostructured ýý-sheet peptides protect membrane proteins. | Tao, Houchao; Lee, Sung Chang; Moeller, Arne; Roy, Rituparna Sinha; Siu, Fai Yiu; Zimmermann, Jorg; Stevens, Raymond C; Potter, Clinton S; Carragher, Bridget; Zhang, Qinghai | Nature methods | 23817067 | 2013 Aug |
| Tripod Amphiphiles for Membrane Protein Manipulation. | Chae, Pil Seok; Laible, Philip D; Gellman, Samuel H | Molecular bioSystems | 23814603 | 2010 |
| Crystallographic data processing for free-electron laser sources. | White, Thomas A; Barty, Anton; Stellato, Francesco; Holton, James M; Kirian, Richard A; Zatsepin, Nadia A; Chapman, Henry N | Acta crystallographica. Section D, Biological crystallography | 23793149 | 2013 Jul |
| Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. | Riley, B E; Lougheed, J C; Callaway, K; Velasquez, M; Brecht, E; Nguyen, L; Shaler, T; Walker, D; Yang, Y; Regnstrom, K; Diep, L; Zhang, Z; Chiou, S; Bova, M; Artis, D R; Yao, N; Baker, J; Yednock, T; Johnston, J A | Nature communications | 23770887 | 2013 |
| Improved production of membrane proteins in Escherichia coli by selective codon substitutions. | Norholm, Morten H H; Toddo, Stephen; Virkki, Minttu T I; Light, Sara; von Heijne, Gunnar; Daley, Daniel O | FEBS letters | 23769986 | 2013 Aug 2 |
| Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline. | Madden, Jeremy T; Toth, Scott J; Dettmar, Christopher M; Newman, Justin A; Oglesbee, Robert A; Hedderich, Hartmut G; Everly, R Michael; Becker, Michael; Ronau, Judith A; Buchanan, Susan K; Cherezov, Vadim; Morrow, Marie E; Xu, Shenglan; Ferguson, Dale; Ma | Journal of synchrotron radiation | 23765294 | 2013 Jul 1 |
| The Structure of the Mercury Transporter MerF in Phospholipid Bilayers: A Large Conformational Rearrangement Results from N-Terminal Truncation. | Lu, George J; Tian, Ye; Vora, Nemil; Marassi, Francesca M; Opella, Stanley J | Journal of the American Chemical Society | 23763519 | 2013 Jun 26 |
| Advances in NMR structures of integral membrane proteins. | Maslennikov, Innokentiy; Choe, Senyon | Current opinion in structural biology | 23721747 | 2013 Aug |
| A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data. | Ahuja, Shivani; Jahr, Nicole; Im, Sang-Choul; Vivekanandan, Subramanian; Popovych, Nataliya; Le Clair, Stephanie V; Huang, Rui; Soong, Ronald; Xu, Jiadi; Yamamoto, Kazutoshi; Nanga, Ravi P; Bridges, Angela; Waskell, Lucy; Ramamoorthy, Ayyalusamy | The Journal of biological chemistry | 23709268 | 2013 Jul 26 |
| Thermostabilisation of the serotonin transporter in a cocaine-bound conformation. | Abdul-Hussein, Saba; Andrell, Juni; Tate, Christopher G | Journal of molecular biology | 23706649 | 2013 Jun 26 |
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| New G-protein-coupled receptor crystal structures: insights and limitations. | Kobilka, Brian; Schertler, Gebhard F X | Trends in pharmacological sciences | 18194818 | 2008 Feb |
| Tailoring 13C labeling for triple-resonance solid-state NMR experiments on aligned samples of proteins. | Sinha, Neeraj; Filipp, Fabian V; Jairam, Lena; Park, Sang Ho; Bradley, Joel; Opella, Stanley J | Magnetic resonance in chemistry : MRC | 18157808 | 2007 Dec |
| In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. | Cherezov, Vadim; Liu, Wei; Derrick, Jeremy P; Luan, Binquan; Aksimentiev, Aleksei; Katritch, Vsevolod; Caffrey, Martin | Proteins | 18076035 | 2008 Apr |
| Crystal polymorphism of protein GB1 examined by solid-state NMR spectroscopy and X-ray diffraction. | Schmidt, Heather L Frericks; Sperling, Lindsay J; Gao, Yi Gui; Wylie, Benjamin J; Boettcher, John M; Wilson, Scott R; Rienstra, Chad M | The journal of physical chemistry. B | 18052145 | 2007 Dec 27 |
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| Flexibility in the ABC transporter MsbA: Alternating access with a twist. | Ward, Andrew; Reyes, Christopher L; Yu, Jodie; Roth, Christopher B; Chang, Geoffrey | Proceedings of the National Academy of Sciences of the United States of America | 18024585 | 2007 Nov 27 |
| High-yield expression and purification of isotopically labeled cytochrome P450 monooxygenases for solid-state NMR spectroscopy. | Rupasinghe, Sanjeewa G; Duan, Hui; Frericks Schmidt, Heather L; Berthold, Deborah A; Rienstra, Chad M; Schuler, Mary A | Biochimica et biophysica acta | 18005930 | 2007 Dec |
| Proton-detected separated local field spectroscopy. | Wu, Chin H; Opella, Stanley J | Journal of magnetic resonance (San Diego, Calif. : 1997) | 17981481 | 2008 Jan |
| TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists. | Menuz, Karen; Stroud, Robert M; Nicoll, Roger A; Hays, Franklin A | Science (New York, N.Y.) | 17975069 | 2007 Nov 2 |
| High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. | Cherezov, Vadim; Rosenbaum, Daniel M; Hanson, Michael A; Rasmussen, Soren G F; Thian, Foon Sun; Kobilka, Tong Sun; Choi, Hee-Jung; Kuhn, Peter; Weis, William I; Kobilka, Brian K; Stevens, Raymond C | Science (New York, N.Y.) | 17962520 | 2007 Nov 23 |
| GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. | Rosenbaum, Daniel M; Cherezov, Vadim; Hanson, Michael A; Rasmussen, Soren G F; Thian, Foon Sun; Kobilka, Tong Sun; Choi, Hee-Jung; Yao, Xiao-Jie; Weis, William I; Stevens, Raymond C; Kobilka, Brian K | Science (New York, N.Y.) | 17962519 | 2007 Nov 23 |
| NMR and mutagenesis of human copper transporter 1 (hCtr1) show that Cys-189 is required for correct folding and dimerization. | Lee, Sangwon; Howell, Stephen B; Opella, Stanley J | Biochimica et biophysica acta | 17959139 | 2007 Dec |
| Membrane protein crystallization in lipidic mesophases. A mechanism study using X-ray microdiffraction. | Cherezov, Vadim; Caffrey, Martin | Faraday discussions | 17955811 | 2007 |
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| Bicelle samples for solid-state NMR of membrane proteins. | De Angelis, Anna A; Opella, Stanley J | Nature protocols | 17947974 | 2007 |
| Structure refinement of the OpcA adhesin using molecular dynamics. | Luan, Binquan; Caffrey, Martin; Aksimentiev, Aleksei | Biophysical journal | 17938421 | 2007 Nov 1 |
| Cell-cell signaling via Eph receptors and ephrins. | Himanen, Juha-Pekka; Saha, Nayanendu; Nikolov, Dimitar B | Current opinion in cell biology | 17928214 | 2007 Oct |
| Sugar binding induces an outward facing conformation of LacY. | Smirnova, Irina; Kasho, Vladimir; Choe, Jun-Yong; Altenbach, Christian; Hubbell, Wayne L; Kaback, H Ronald | Proceedings of the National Academy of Sciences of the United States of America | 17925435 | 2007 Oct 16 |
| Site-directed alkylation of LacY: effect of the proton electrochemical gradient. | Nie, Yiling; Ermolova, Natalia; Kaback, H Ronald | Journal of molecular biology | 17920075 | 2007 Nov 23 |
| NMR structural studies of the bacterial outer membrane protein OmpX in oriented lipid bilayer membranes. | Mahalakshmi, Radhakrishnan; Franzin, Carla M; Choi, Jungyuen; Marassi, Francesca M | Biochimica et biophysica acta | 17916325 | 2007 Dec |
| Transmembrane domain of myelin protein zero can form dimers: possible implications for myelin construction. | Plotkowski, Megan L; Kim, Sanguk; Phillips, Martin L; Partridge, Anthony W; Deber, Charles M; Bowie, James U | Biochemistry | 17915947 | 2007 Oct 30 |
| Solid-state protein-structure determination with proton-detected triple-resonance 3D magic-angle-spinning NMR spectroscopy. | Zhou, Donghua H; Shea, John J; Nieuwkoop, Andrew J; Franks, W Trent; Wylie, Benjamin J; Mullen, Charles; Sandoz, Dennis; Rienstra, Chad M | Angewandte Chemie (International ed. in English) | 17907259 | 2007 |
| Structural determination of wild-type lactose permease. | Guan, Lan; Mirza, Osman; Verner, Gillian; Iwata, So; Kaback, H Ronald | Proceedings of the National Academy of Sciences of the United States of America | 17881559 | 2007 Sep 25 |
| High resolution 1H NMR of a lipid cubic phase using a solution NMR probe. | Boyle-Roden, E; Hoefer, N; Dey, K K; Grandinetti, P J; Caffrey, M | Journal of magnetic resonance (San Diego, Calif. : 1997) | 17855136 | 2007 Nov |
| Proton-detected solid-state NMR spectroscopy of fully protonated proteins at 40 kHz magic-angle spinning. | Zhou, Donghua H; Shah, Gautam; Cormos, Mircea; Mullen, Charles; Sandoz, Dennis; Rienstra, Chad M | Journal of the American Chemical Society | 17725352 | 2007 Sep 26 |
| Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression. | Hanson, Michael A; Brooun, Alexei; Baker, Kent A; Jaakola, Veli-Pekka; Roth, Chris; Chien, Ellen Y T; Alexandrov, Alexander; Velasquez, Jeffrey; Davis, Leila; Griffith, Mark; Moy, Kin; Ganser-Pornillos, Barbie K; Hua, Yuanzi; Kuhn, Peter; Ellis, Sam; Yeag | Protein expression and purification | 17723307 | 2007 Nov |
| An efficient (1)H/(31)P double-resonance solid-state NMR probe that utilizes a scroll coil. | Grant, Christopher V; Sit, Siu-Ling; De Angelis, Anna A; Khuong, Kelli S; Wu, Chin H; Plesniak, Leigh A; Opella, Stanley J | Journal of magnetic resonance (San Diego, Calif. : 1997) | 17719813 | 2007 Oct |
| Modular total chemical synthesis of a human immunodeficiency virus type 1 protease. | Johnson, Erik C B; Malito, Enrico; Shen, Yuequan; Rich, Dan; Tang, Wei-Jen; Kent, Stephen B H | Journal of the American Chemical Society | 17705484 | 2007 Sep 19 |
| Designing facial amphiphiles for the stabilization of integral membrane proteins. | Zhang, Qinghai; Ma, Xingquan; Ward, Andrew; Hong, Wen-Xu; Jaakola, Veli-Pekka; Stevens, Raymond C; Finn, M G; Chang, Geoffrey | Angewandte Chemie (International ed. in English) | 17691085 | 2007 |
| LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. | Zhou, Zheng; Zhen, Juan; Karpowich, Nathan K; Goetz, Regina M; Law, Christopher J; Reith, Maarten E A; Wang, Da-Neng | Science (New York, N.Y.) | 17690258 | 2007 Sep 7 |
| Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus. | Hofer, Nicole; Kolaj, Olga; Li, Hui; Cherezov, Vadim; Gillilan, Richard; Wall, J Gerard; Caffrey, Martin | Acta crystallographica. Section F, Structural biology and crystallization communications | 17671365 | 2007 Aug 1 |
| Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit. | Rajagopal, Sudarshan; Kent, Stephen B H | Protein science : a publication of the Protein Society | 17660260 | 2007 Sep |
| When biochemistry meets structural biology: the cautionary tale of EmrE. | Schuldiner, Shimon | Trends in biochemical sciences | 17452106 | 2007 Jun |
| Crystal structure of the human ephrin-A5 ectodomain. | Nikolov, Dimitar; Li, Chen; Lackmann, Martin; Jeffrey, Philip; Himanen, Juha | Protein science : a publication of the Protein Society | 17400922 | 2007 May |
| Using a multijunction microfluidic device to inject substrate into an array of preformed plugs without cross-contamination: comparing theory and experiments. | Li, Liang; Boedicker, James Q; Ismagilov, Rustem F | Analytical chemistry | 17338503 | 2007 Apr 1 |
| Kinetic analysis of the binding of monomeric and dimeric ephrins to Eph receptors: correlation to function in a growth cone collapse assay. | Pabbisetty, Kumar B; Yue, Xin; Li, Chen; Himanen, Juha-Pekka; Zhou, Renping; Nikolov, Dimitar B; Hu, Longqin | Protein science : a publication of the Protein Society | 17322526 | 2007 Mar |
| Partial (13)C and (15)N chemical-shift assignments of the disulfide-bond-forming enzyme DsbB by 3D magic-angle spinning NMR spectroscopy. | Li, Ying; Berthold, Deborah A; Frericks, Heather L; Gennis, Robert B; Rienstra, Chad M | Chembiochem : a European journal of chemical biology | 17285659 | 2007 Mar 5 |
| NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL. | Malia, Thomas J; Wagner, Gerhard | Biochemistry | 17209561 | 2007 Jan 16 |
| Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins. | Li, Liang; Mustafi, Debarshi; Fu, Qiang; Tereshko, Valentina; Chen, Delai L; Tice, Joshua D; Ismagilov, Rustem F | Proceedings of the National Academy of Sciences of the United States of America | 17159147 | 2006 Dec 19 |
| Exploratory synthesis of peptide-alpha-thioester segments spanning the polypeptide sequence of the delta-opioid receptor, a G protein-coupled receptor. | Johnson, Erik C B; Kent, Stephen B H | Biopolymers | 17120238 | 2007 |
| Reactions in droplets in microfluidic channels. | Song, Helen; Chen, Delai L; Ismagilov, Rustem F | Angewandte Chemie (International ed. in English) | 17086584 | 2006 Nov 13 |
| Ultrafast hydration dynamics in the lipidic cubic phase: Discrete water structures in nanochannels. | Kim, Jongjoo; Lu, Wenyun; Qiu, Weihong; Wang, Lijuan; Caffrey, Martin; Zhong, Dongping | The journal of physical chemistry. B | 17064169 | 2006 Nov 2 |
| Controlling the passage of light through metal microchannels by nanocoatings of phospholipids. | Teeters-Kennedy, Shannon M; Rodriguez, Kenneth R; Rogers, Trisha M; Zomchek, Keith A; Williams, Shaun M; Sudnitsyn, Alexandra; Carter, Lauren; Cherezov, Vadim; Caffrey, Martin; Coe, James V | The journal of physical chemistry. B | 17064131 | 2006 Nov 2 |
| In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution. | Cherezov, V; Yamashita, E; Liu, W; Zhalnina, M; Cramer, W A; Caffrey, M | Journal of molecular biology | 17028020 | 2006 Dec 8 |
| Interactions of tryptophan, tryptophan peptides, and tryptophan alkyl esters at curved membrane interfaces. | Liu, Wei; Caffrey, Martin | Biochemistry | 17002272 | 2006 Oct 3 |
| Structure determination of a membrane protein with two trans-membrane helices in aligned phospholipid bicelles by solid-state NMR spectroscopy. | De Angelis, Anna A; Howell, Stanley C; Nevzorov, Alexander A; Opella, Stanley J | Journal of the American Chemical Society | 16967977 | 2006 Sep 20 |
| Identification of individual protein-ligand NOEs in the limit of intermediate exchange. | Reibarkh, Mikhail; Malia, Thomas J; Hopkins, Brian T; Wagner, Gerhard | Journal of biomolecular NMR | 16964534 | 2006 Sep |
| Magic-angle spinning solid-state NMR of a 144 kDa membrane protein complex: E. coli cytochrome bo3 oxidase. | Frericks, Heather L; Zhou, Donghua H; Yap, Lai Lai; Gennis, Robert B; Rienstra, Chad M | Journal of biomolecular NMR | 16964530 | 2006 Sep |
| Production of arrays of chemically distinct nanolitre plugs via repeated splitting in microfluidic devices. | Adamson, David N; Mustafi, Debarshi; Zhang, John X J; Zheng, Bo; Ismagilov, Rustem F | Lab on a chip | 16929397 | 2006 Sep |
| High-resolution NMR spectroscopy of a GPCR in aligned bicelles. | Park, Sang Ho; Prytulla, Stefan; De Angelis, Anna A; Brown, Jonathan Miles; Kiefer, Hans; Opella, Stanley J | Journal of the American Chemical Society | 16756269 | 2006 Jun 14 |
| Microfluidic cartridges preloaded with nanoliter plugs of reagents: an alternative to 96-well plates for screening. | Chen, Delai L; Ismagilov, Rustem F | Current opinion in chemical biology | 16677848 | 2006 Jun |
| Room to move: crystallizing membrane proteins in swollen lipidic mesophases. | Cherezov, Vadim; Clogston, Jeffrey; Papiz, Miroslav Z; Caffrey, Martin | Journal of molecular biology. | 16490208 | 2006 Apr 14 |
| NMR distinction of single- and multiple-mode binding of small-molecule protein ligands. | Reibarkh, Mikhail; Malia, Thomas J; Wagner, Gerhard | Journal of the American Chemical Society | 16478139 | 2006 Feb 22 |
| An architectural framework that may lie at the core of the postsynaptic density. | Baron, Marisa K; Boeckers, Tobias M; Vaida, Bianca; Faham, Salem; Gingery, Mari; Sawaya, Michael R; Salyer, Danielle; Gundelfinger, Eckart D; Bowie, James U | Science (New York, N.Y.) | 16439662 | 2006 Jan 27 |
| X-ray structure of the EmrE multidrug transporter in complex with a substrate. | Pornillos, Owen; Chen, Yen-Ju; Chen, Andy P; Chang, Geoffrey | Science (New York, N.Y.) | 16373573 | 2005 Dec 23 |
| The Membrane Protein Data Bank. | Raman, P; Cherezov, V; Caffrey, M | Cellular and molecular life sciences : CMLS | 16314922 | 2006 Jan |
| Characterization of bacterial drug antiporters homologous to mammalian neurotransmitter transporters. | Vardy, Eyal; Steiner-Mordoch, Sonia; Schuldiner, Shimon | Journal of bacteriology. | 16237035 | 2005 Nov |
| The past, present and future of cell-free protein synthesis. | Katzen, Federico; Chang, Geoffrey; Kudlicki, Wieslaw | Trends in biotechnology. | 15734558 | 2005 Mar |
| Synthesis of fluorescein labeled 7-methylguanosinemonophosphate. | Natarajan, Amarnath; Moerke, Nathan; Fan, Yun-Hua; Chen, Han; Christ, William J; Wagner, Gerhard; Halperin, Jose A | Bioorganic & medicinal chemistry letters | 15109672 | 2004 May 17 |
