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Funded Research

**Membrane Protein Productionfor Structure Determination(R01)**
**RFA-RM-09-012**
PI Name	Institution Name	Title
BETENBAUGH, MICHAEL J	JOHNS HOPKINS UNIVERSITY	Evolving Membrane Proteins for High Level Expression in Modified Mammalian Cells
CARRAGHER, BRIDGET OLIVIA	SCRIPPS RESEARCH INSTITUTE	A Helical Crystallization Pipeline for Membrane Protein Structure by TEM
CHOE, SENYON	SALK INSTITUTE FOR BIOLOGICAL STUDIES	Cell-Free Expression of Human Integral Membrane Proteins for Structural Studies
DELUCAS, LAWRENCE J	UNIVERSITY OF ALABAMA AT BIRMINGHAM	Production & Crystallization of Membrane Protein for 3D Structure
FROMME, PETRA.	ARIZONA STATE UNIVERSITY-TEMPE CAMPUS	Femtosecond Nano-Crystallography of Membrane Proteins
GENNIS, ROBERT B	UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN	Using Extreme Thermophiles for the Homologous Expression of Membrane Proteins
GUAN, LAN	TEXAS TECH UNIVERSITY HEALTH SCIS CENTER	Novel Capture Reagents for Membrane Protein Structure Determination
IVERSON, T M	VANDERBILT UNIVERSITY	Stabilization of Membrane Protein Signaling Complexes
MAYNARD, JENNIFER A	UNIVERSITY OF TEXAS AUSTIN	Engineered Antibody Fragments for Co-Crystallization with Signal Peptide Peptidase
RAMAMOORTHY, AYYALUSAMY	UNIVERSITY OF MICHIGAN AT ANN ARBOR	Rapid and Efficient Production of Functional Cytochrome P450 Enzymatic Complexes
STOKES, DAVID L	NEW YORK STRUCTURAL BIOLOGY CENTER	High Throughput Pipeline for Electron Crystallography
WOYCHIK, NANCY ANN	UNIV OF MED/DENT NJ-R W JOHNSON MED SCH	Membrane Protein Production Using the Yeast SPP System

**Membrane Protein Production and Structure Determination (R01)**
**(RFA-RM-07-003)**
PI Name	Institution Name	Title
ALLEN, PAUL D.	BRIGHAM AND WOMEN'S HOSPITAL	Integral Membrane Protein Overexpression Using Organ Bioreactors
BOWIE, JAMES U.	UNIVERSITY OF CALIFORNIA LOS ANGELES	Improving Membrane Protein Crystallization
DELUCAS, LAWRENCE	UNIVERSITY OF ALABAMA AT BIRMINGHAN	Innovative Methods for Membrane Protein Crystallization
NAVARRO, JAVIER V.	UNIVERSITY OF TEXAS MEDICAL BR GALVESTON	Structural Biology of G Protein-Coupled Receptors
SANDERS, CHARLES R.	VANDERBILT UNIVERSITY.	Overcoming the Barriers to Structural Analysis of GPCRs
SPILLER, BENJAMIN W.	VANDERBILT UNIVERSITY	Structural Studies of Voltage Gating in Voltage-Gated Sodium Channels
STOKES, DAVID L.	NEW YORK STRUCTURAL BIOLOGY CENTER	Membrane Protein Structure by Electron Crystallography

**Membrane Protein Production and Structure Determination (R01- R21- P01)**
**RFA-RM-04-026**
PI Name	Institution Name	Title
BOWIE, JAMES U	UNIVERSITY OF CALIFORNIA LOS ANGELES	Generation of Membrane Protein Production Strains
CAFFREY, MARTIN D.	UNIVERSITY OF LIMERICK RESEARCH FDN	Membrane Proteins. Crystallogenesis and X-ray Structure
GERFEN, GARY J.	YESHIVA UNIVERSITY	Proton Crystallography of Membrane Proteins Using High Frequency ENDOR
GROS, PHILIPPE	MC GILL UNIVERSITY	Expression of ABC Transporters in Pichia Pastoris
HIMANEN, JUHA P	SLOAN-KETTERING INSTITUTE FOR CANCER RES	Expression and Structural Study of Eph Receptor Kinases
HUNT, JOHN F	COLUMBIA UNIV NEW YORK MORNINGSIDE	A Chemical Genetics Approach to Improved IMP Expression in E. Coli
ISMAGILOV, RUSTEM F	UNIVERSITY OF CHICAGO	Enabling Nanoliter Membrane Protein Crystallization
KENIS, PAUL J	UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN	Innovative Methods for Membrane Protein Crystallization
KENT, STEPHEN B.H	UNIVERSITY OF CHICAGO	A Systematic Approach to the Chemical Synthesis of G-Protein Coupled Receptors
KOBILKA, BRIAN K	STANFORD UNIVERSITY	Chimeric Proteins to Enhance Crystal Formation of G Protein Coupled Receptors
LAIBLE, PHILIP D	UNIVERSITY OF CHICAGO	Reagents: Promote Membrane Protein Stability and Crystallization
LOLL, PATRICK J	DREXEL UNIVERSITY COLLEGE OF MEDICINE	Mapping the Crystallization Slot for Membrane Proteins
MARASSI, FRANCESCA M	BURNHAM INSTITUTE	Structure of a Beta Barrel Membrane Protein in Lipid Bilayer Membranes
MILLIGAN, RONALD A	SCRIPPS RESEARCH INSTITUTE	ELECTRON MICROSCOPY OF MEMBRANE PROTEINS
OPELLA, STANLEY J	UNIVERSITY OF CALIFORNIA SAN DIEGO	Membrane Protein Structures in Phospholipid Bilayers by Solid State NMR
RIENSTRA, CHAD M	UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN	Structure and Function of Membrane Protein Complexes by Solid State NMR
WAGNER, GERHARD	HARVARD UNIVERSITY (MEDICAL SCHOOL)	Expression, Labeling and NMR Structure Determination of Integral Membrane Protein
WANG, DA-NENG	NEW YORK UNIVERSITY SCHOOL OF MEDICINE	Crystallization of Neurotransmitter Transporter Homologs
WIENER, MICHAEL C.	UNIVERSITY OF VIRGINIA CHARLOTTESVILLE	Improved Methods for Membrane Protein Crystallization

**Centers for Innovation in Membrane Protein Production for Structure Determination (P50)**
**RFA-RM-08-019**
PI Name	Institution Name	Title
CRAMER, WILLIAM A.	PURDUE UNIVERSITY WEST LAFAYETTE	Improving Rate/Quality Limitations in Membrane Protein Structure Determination
STEVENS, RAYMOND C.	SCRIPPS RESEARCH INSTITUTE	Joint Center for Integral Membrane Protein Technologies-Complexes (JCIMPT-Complexes)
STROUD, ROBERT M.	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	Membrane Protein Expression Center (MPEC)

**Centers for Innovation in Membrane Protein Production (P50)**
**RFA-RM-04-009**
PI Name	Institution Name	Title
STEVENS, RAYMOND C	SCRIPPS RESEARCH INSTITUTE	JCSG Center for Innovative Membrane Protein Technologies
STROUD, ROBERT M	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	Center for Innovation in Membrane Protein Production

This page last reviewed on April 12, 2024

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