Eligibility

The Transformative Research Award is open to individual or teams of scientists at any career stage. Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their organization to develop an application for support.

Applications are welcome in all research areas broadly relevant to the mission of NIH. These areas include, but are not limited to, the behavioral, medical, natural, social, applied, and formal sciences. Research may be basic, translational, or clinical. The primary requirements are that the research be highly innovative and have the potential for unusually broad impact.

Steps to Determine Your Eligibility

1. Fit NIH Mission and Goals

   NIH seeks fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The Transformative Research Award welcomes all areas of research relevant to this mission, including (but not limited to) topics in behavioral, medical, natural, social, applied, and formal sciences. Research may be basic, translational, or clinical. The primary requirements are that the research be highly innovative and have the potential for unusually broad impact.

2. Fit the Purpose of the Transformative Research Award

   The award supports individual or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Transformative Research Award applications should propose research substantially different from current mainstream research. No preliminary data or detailed experimental plans are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of science relevant to the NIH.

3. Understand how the Transformative Research Award Differs from a Traditional R01

   Several key features of the initiative are designed to emphasize to applicants and peer reviewers that Transformative Research Award applications are very different from conventional, investigator-initiated research applications. The Transformative Research Award application focuses on the importance of the problem, the novelty of the hypothesis and/or the proposed methodology, and the magnitude of the potential impact rather than on preliminary data or experimental details. Reviewers will be instructed to emphasize the significance and innovation of the application in their evaluations. Applicants and reviewers should keep the goal of the Transformative Research Award initiative in mind throughout the process– to solicit and fund unusually innovative and potentially transformative research.

4. Get Additional Questions Answered

   If you have questions about the fit of your research idea for the Transformative Research Award, check out the Frequently Asked Questions section and past Q&A webinar posted on the website. You can also contact NIH staff at [email protected].
    

More questions? Contact us at [email protected].