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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Author Journal Name PubMedID Journal Abbreviation Publication Date
NMR: an essential structural tool for integrative studies of T cell development, pMHC ligand recognition and TCR mechanobiology. Mallis RJ, Brazin KN, Duke-Cohan JS, Hwang W, Wang JH, Wagner G, Arthanari H, Lang MJ, Reinherz EL Journal of biomolecular NMR 30815789 J Biomol NMR 2019 Jul
TCR-pMHC encounter differentially regulates transcriptomes of tissue-resident CD8 T cells. Yoshizawa A, Bi K, Keskin DB, Zhang G, Reinhold B, Reinherz EL European journal of immunology 28872670 Eur J Immunol 2018 Jan
The T Cell Antigen Receptor α Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations. Brazin KN, Mallis RJ, Boeszoermenyi A, Feng Y, Yoshizawa A, Reche PA, Kaur P, Bi K, Hussey RE, Duke-Cohan JS, Song L, Wagner G, Arthanari H, Lang MJ, Reinherz EL Immunity 30389415 Immunity 2018 Nov 20
αβ T Cell Receptor Mechanosensing Forces out Serial Engagement. Feng Y, Reinherz EL, Lang MJ Trends in immunology 30060805 Trends Immunol 2018 Aug
Reply to: APP gene copy number changes reflect exogenous contamination. Lee MH, Liu CS, Zhu Y, Kaeser GE, Rivera R, Romanow WJ, Kihara Y, Chun J Nature 32814882 Nature 2020 Aug
Mosaic Somatic Gene Recombination as a Potentially Unifying Hypothesis for Alzheimer's Disease. Kaeser GE, Chun J Frontiers in genetics 32457796 Front Genet 2020
Brain cell somatic gene recombination and its phylogenetic foundations. Kaeser G, Chun J The Journal of biological chemistry 32699111 J Biol Chem 2020 Sep 4
The Gene Conundrum in Alzheimer's Disease. Chun J Cerebrum : the Dana forum on brain science 32206173 Cerebrum 2019 Nov-Dec
The African Turquoise Killifish: A Scalable Vertebrate Model for Aging and Other Complex Phenotypes. Boos F, Chen J, Brunet A Cold Spring Harbor protocols 37100468 Cold Spring Harb Protoc 2024 Mar 1
Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence. Sahai-Hernandez P, Pouget C, Eyal S, Svoboda O, Chacon J, Grimm L, Gjøen T, Traver D eLife 37695317 Elife 2023 Sep 11
Cardiac function modulates endocardial cell dynamics to shape the cardiac outflow tract. Sidhwani P, Leerberg DM, Boezio GLM, Capasso TL, Yang H, Chi NC, Roman BL, Stainier DYR, Yelon D Development (Cambridge, England) 32439760 Development 2020 Jun 17
Tutorial: practical considerations for tissue clearing and imaging. Weiss KR, Voigt FF, Shepherd DP, Huisken J Nature protocols 34021294 Nat Protoc 2021 Jun
Deconvolution of polygenic risk score in single cells unravels cellular and molecular heterogeneity of complex human diseases. Zhang S, Shu H, Zhou J, Rubin-Sigler J, Yang X, Liu Y, Cooper-Knock J, Monte E, Zhu C, Tu S, Li H, Tong M, Ecker JR, Ichida JK, Shen Y, Zeng J, Tsao PS, Snyder MP bioRxiv : the preprint server for biology 38798507 bioRxiv 2024 May 14
Deep learning modeling of rare noncoding genetic variants in human motor neurons defines CCDC146 as a therapeutic target for ALS. Zhang S, Moll T, Rubin-Sigler J, Tu S, Li S, Yuan E, Liu M, Butt A, Harvey C, Gornall S, Alhalthli E, Shaw A, Souza CDS, Ferraiuolo L, Hornstein E, Shelkovnikova T, van Dijk CH, Timpanaro IS, Kenna KP, Zeng J, Tsao PS, Shaw PJ, Ichida JK, Cooper-Knock J, Snyder MP medRxiv : the preprint server for health sciences 38633814 medRxiv 2024 Apr 1
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS. Hung ST, Linares GR, Chang WH, Eoh Y, Krishnan G, Mendonca S, Hong S, Shi Y, Santana M, Kueth C, Macklin-Isquierdo S, Perry S, Duhaime S, Maios C, Chang J, Perez J, Couto A, Lai J, Li Y, Alworth SV, Hendricks E, Wang Y, Zlokovic BV, Dickman DK, Parker JA, Zarnescu DC, Gao FB, Ichida JK Cell 36754049 Cell 2023 Feb 16
CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology. Ortega JA, Sasselli IR, Boccitto M, Fleming AC, Fortuna TR, Li Y, Sato K, Clemons TD, Mckenna ED, Nguyen TP, Anderson EN, Asin J, Ichida JK, Pandey UB, Wolin SL, Stupp SI, Kiskinis E Science advances 37948524 Sci Adv 2023 Nov 10
SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS. Linares GR, Li Y, Chang WH, Rubin-Sigler J, Mendonca S, Hong S, Eoh Y, Guo W, Huang YH, Chang J, Tu S, Dorjsuren N, Santana M, Hung ST, Yu J, Perez J, Chickering M, Cheng TY, Huang CC, Lee SJ, Deng HJ, Bach KT, Gray K, Subramanyam V, Rosenfeld J, Alworth SV, Goodarzi H, Ichida JK Cell stem cell 36736291 Cell Stem Cell 2023 Feb 2
Body mass index associates with amyotrophic lateral sclerosis survival and metabolomic profiles. Goutman SA, Boss J, Iyer G, Habra H, Savelieff MG, Karnovsky A, Mukherjee B, Feldman EL Muscle & nerve 36321729 Muscle Nerve 2023 Mar
Stem cell therapy for central nervous system disorders: Metabolic interactions between transplanted cells and local microenvironments. Sakowski SA, Chen KS Neurobiology of disease 35988874 Neurobiol Dis 2022 Oct 15
Occupational history associates with ALS survival and onset segment. Goutman SA, Boss J, Godwin C, Mukherjee B, Feldman EL, Batterman SA Amyotrophic lateral sclerosis & frontotemporal degeneration 36193557 Amyotroph Lateral Scler Frontotemporal Degener 2023 May
Gut microbiome correlates with plasma lipids in amyotrophic lateral sclerosis. Guo K, Figueroa-Romero C, Noureldein MH, Murdock BJ, Savelieff MG, Hur J, Goutman SA, Feldman EL Brain : a journal of neurology 37721161 Brain 2024 Feb 1
Role of the Exposome in Neurodegenerative Disease: Recent Insights and Future Directions. Sakowski SA, Koubek EJ, Chen KS, Goutman SA, Feldman EL Annals of neurology 38411261 Ann Neurol 2024 Apr
Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study. Goutman SA, Boss J, Jang DG, Piecuch C, Farid H, Batra M, Mukherjee B, Feldman EL, Batterman SA Amyotrophic lateral sclerosis & frontotemporal degeneration 38557405 Amyotroph Lateral Scler Frontotemporal Degener 2024 Aug
Variable selection with multiply-imputed datasets: choosing between stacked and grouped methods. Du J, Boss J, Han P, Beesley LJ, Kleinsasser M, Goutman SA, Batterman S, Feldman EL, Mukherjee B Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America 36644406 J Comput Graph Stat 2022
Priorities and Recommendations to Make ALS a Livable Disease Emanating from the 2024 National Academies of Sciences, Engineering, and Medicine Report Living with ALS. Howard IM, Babu S, Carter C, Sakowski SA, Kurent JE, Cudkowicz ME, Feldman EL Annals of neurology 39390661 Ann Neurol 2024 Dec
Avocational exposure associations with ALS risk, survival, and phenotype: A Michigan-based case-control study. Goutman SA, Boss J, Jang DG, Piecuch C, Farid H, Batra M, Mukherjee B, Feldman EL, Batterman SA Journal of the neurological sciences 38278093 J Neurol Sci 2024 Feb 15
Cumulative Genetic Score and C9orf72 Repeat Status Independently Contribute to Amyotrophic Lateral Sclerosis Risk in 2 Case-Control Studies. Dou J, Bakulski K, Guo K, Hur J, Zhao L, Saez-Atienzar S, Stark A, Chia R, García-Redondo A, Rojas-Garcia R, Vázquez Costa JF, Fernandez Santiago R, Bandres-Ciga S, Gómez-Garre P, Periñán MT, Mir P, Pérez-Tur J, Cardona F, Menendez-Gonzalez M, Riancho J, Borrego-Hernández D, Galán-Dávila L, Infante Ceberio J, Pastor P, Paradas C, Dols-Icardo O, Traynor BJ, Feldman EL, Goutman SA, Spanish Neurological Consortium Neurology. Genetics 37293291 Neurol Genet 2023 Aug
Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort. Goutman SA, Boss J, Jang DG, Mukherjee B, Richardson RJ, Batterman S, Feldman EL Journal of neurology, neurosurgery, and psychiatry 37758454 J Neurol Neurosurg Psychiatry 2024 Feb 14
Multiple metal exposures associate with higher amyotrophic lateral sclerosis risk and mortality independent of genetic risk and correlate to self-reported exposures: a case-control study. Jang DG, Dou JF, Koubek EJ, Teener S, Zhou L, Bakulski KM, Mukherjee B, Batterman SA, Feldman EL, Goutman SA Journal of neurology, neurosurgery, and psychiatry 39107037 J Neurol Neurosurg Psychiatry 2024 Aug 6
Impact of the Adverse Social Exposome on Survival in Individuals With Amyotrophic Lateral Sclerosis. Jang DG, Kind AJ, Patterson A, Pedde M, Powell WR, Feldman EL, Goutman SA Neurology 39879575 Neurology 2025 Feb 25
Recent advances in the diagnosis and prognosis of amyotrophic lateral sclerosis. Goutman SA, Hardiman O, Al-Chalabi A, Chió A, Savelieff MG, Kiernan MC, Feldman EL The Lancet. Neurology 35334233 Lancet Neurol 2022 May
Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis. Goutman SA, Hardiman O, Al-Chalabi A, Chió A, Savelieff MG, Kiernan MC, Feldman EL The Lancet. Neurology 35334234 Lancet Neurol 2022 May
Improving prediction models of amyotrophic lateral sclerosis (ALS) using polygenic, pre-existing conditions, and survey-based risk scores in the UK Biobank. Jin W, Boss J, Bakulski KM, Goutman SA, Feldman EL, Fritsche LG, Mukherjee B medRxiv : the preprint server for health sciences 38585910 medRxiv 2024 Mar 30
Nanoplastics and Neurodegeneration in ALS. Eisen A, Pioro EP, Goutman SA, Kiernan MC Brain sciences 38790450 Brain Sci 2024 May 7
Awareness and care practices for rare neurologic diseases among senior neurologists: A global survey. Jang DG, Federico A, Savelieff MG, Grisold W, Mancuso M, Molnar MJ, Feldman EL, Reynolds EL, World Federation of Neurology Subspecialist Group on Rare Neurologic Diseases Journal of the neurological sciences 39855013 J Neurol Sci 2025 Mar 15
Longitudinal Metabolomics in Amyotrophic Lateral Sclerosis Implicates Impaired Lipid Metabolism. Guo K, Savelieff MG, Jang DG, Teener SJ, Zhao L, Hur J, Goutman SA, Feldman EL Annals of neurology 39976286 Ann Neurol 2025 Feb 20
Epigenetic age acceleration is associated with occupational exposures, sex, and survival in amyotrophic lateral sclerosis. Zhao Y, Li X, Wang K, Iyer G, Sakowski SA, Zhao L, Teener S, Bakulski KM, Dou JF, Traynor BJ, Karnovsky A, Batterman SA, Feldman EL, Sartor MA, Goutman SA EBioMedicine 39369616 EBioMedicine 2024 Nov
Metal mixtures associate with higher amyotrophic lateral sclerosis risk and mortality independent of genetic risk and correlate to self-reported exposures: a case-control study. Jang DG, Dou J, Koubek EJ, Teener S, Zhao L, Bakulski KM, Mukherjee B, Batterman SA, Feldman EL, Goutman SA medRxiv : the preprint server for health sciences 38464233 medRxiv 2024 Feb 28
Improving prediction models of amyotrophic lateral sclerosis (ALS) using polygenic, pre-existing conditions, and survey-based risk scores in the UK Biobank. Jin W, Boss J, Bakulski KM, Goutman SA, Feldman EL, Fritsche LG, Mukherjee B Journal of neurology 39249108 J Neurol 2024 Oct
miRNA analysis reveals novel dysregulated pathways in amyotrophic lateral sclerosis. Hur J, Paez-Colasante X, Figueroa-Romero C, Lo TW, Barmada SJ, Paulsen MT, Ljungman M, Alakwaa FM, Savelieff MG, Goutman SA, Feldman EL Human molecular genetics 36219176 Hum Mol Genet 2023 Mar 6
Amyotrophic lateral sclerosis. Feldman EL, Goutman SA, Petri S, Mazzini L, Savelieff MG, Shaw PJ, Sobue G Lancet (London, England) 36116464 Lancet 2022 Oct 15
The amyotrophic lateral sclerosis exposome: recent advances and future directions. Goutman SA, Savelieff MG, Jang DG, Hur J, Feldman EL Nature reviews. Neurology 37709948 Nat Rev Neurol 2023 Oct
Local translation in primary afferents and its contribution to pain. Gale JR, Gedeon JY, Donnelly CJ, Gold MS Pain 35438669 Pain 2022 Dec 1
Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD. Pineda SS, Lee H, Ulloa-Navas MJ, Linville RM, Garcia FJ, Galani K, Engelberg-Cook E, Castanedes MC, Fitzwalter BE, Pregent LJ, Gardashli ME, DeTure M, Vera-Garcia DV, Hucke ATS, Oskarsson BE, Murray ME, Dickson DW, Heiman M, Belzil VV, Kellis M Cell 38521060 Cell 2024 Apr 11
Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology. Mathys H, Peng Z, Boix CA, Victor MB, Leary N, Babu S, Abdelhady G, Jiang X, Ng AP, Ghafari K, Kunisky AK, Mantero J, Galani K, Lohia VN, Fortier GE, Lotfi Y, Ivey J, Brown HP, Patel PR, Chakraborty N, Beaudway JI, Imhoff EJ, Keeler CF, McChesney MM, Patel HH, Patel SP, Thai MT, Bennett DA, Kellis M, Tsai LH Cell 37774677 Cell 2023 Sep 28
Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion. Xiong X, James BT, Boix CA, Park YP, Galani K, Victor MB, Sun N, Hou L, Ho LL, Mantero J, Scannail AN, Dileep V, Dong W, Mathys H, Bennett DA, Tsai LH, Kellis M Cell 37774680 Cell 2023 Sep 28
Single-cell multiregion dissection of Alzheimer's disease. Mathys H, Boix CA, Akay LA, Xia Z, Davila-Velderrain J, Ng AP, Jiang X, Abdelhady G, Galani K, Mantero J, Band N, James BT, Babu S, Galiana-Melendez F, Louderback K, Prokopenko D, Tanzi RE, Bennett DA, Tsai LH, Kellis M Nature 39048816 Nature 2024 Aug
Power of inclusion: Enhancing polygenic prediction with admixed individuals. Tanigawa Y, Kellis M American journal of human genetics 37890495 Am J Hum Genet 2023 Nov 2
CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function. Xie L, Merjane J, Bergmann CA, Xu J, Hurtle B, Donnelly CJ bioRxiv : the preprint server for biology 39026766 bioRxiv 2024 Jul 12
Multifaceted Role of Specialized Neuropeptide-Intensive Neurons on the Selective Vulnerability to Alzheimer's Disease in the Human Brain. Li M, Flack N, Larsen PA Biomolecules 39766225 Biomolecules 2024 Nov 27
Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy. Aikio M, Odeh HM, Wobst HJ, Lee BL, Chan Ú, Mauna JC, Mack KL, Class B, Ollerhead TA, Ford AF, Barbieri EM, Cupo RR, Drake LE, Smalley JL, Lin YT, Lam S, Thomas R, Castello N, Baral A, Beyer JN, Najar MA, Dunlop J, Gitler AD, Javaherian A, Kaye JA, Burslem GM, Brown DG, Donnelly CJ, Finkbeiner S, Moss SJ, Brandon NJ, Shorter J Cell reports 39817908 Cell Rep 2025 Jan 28
Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease. Sun N, Akay LA, Murdock MH, Park Y, Galiana-Melendez F, Bubnys A, Galani K, Mathys H, Jiang X, Ng AP, Bennett DA, Tsai LH, Kellis M Nature neuroscience 37264161 Nat Neurosci 2023 Jun
Multifaceted impact of specialized neuropeptide-intensive neurons on the selective vulnerability in Alzheimer's disease. Li M, Flack N, Larsen PA bioRxiv : the preprint server for biology 38014130 bioRxiv 2024 Apr 22
Human microglial state dynamics in Alzheimer's disease progression. Sun N, Victor MB, Park YP, Xiong X, Scannail AN, Leary N, Prosper S, Viswanathan S, Luna X, Boix CA, James BT, Tanigawa Y, Galani K, Mathys H, Jiang X, Ng AP, Bennett DA, Tsai LH, Kellis M Cell 37774678 Cell 2023 Sep 28
Integrating single-cell RNA-seq datasets with substantial batch effects. Hrovatin K, Moinfar AA, Zappia L, Lapuerta AT, Lengerich B, Kellis M, Theis FJ bioRxiv : the preprint server for biology 37961672 bioRxiv 2024 Feb 10
Integrated multimodal cell atlas of Alzheimer's disease. Gabitto MI, Travaglini KJ, Rachleff VM, Kaplan ES, Long B, Ariza J, Ding Y, Mahoney JT, Dee N, Goldy J, Melief EJ, Agrawal A, Kana O, Zhen X, Barlow ST, Brouner K, Campos J, Campos J, Carr AJ, Casper T, Chakrabarty R, Clark M, Cool J, Dalley R, Darvas M, Ding SL, Dolbeare T, Egdorf T, Esposito L, Ferrer R, Fleckenstein LE, Gala R, Gary A, Gelfand E, Gloe J, Guilford N, Guzman J, Hirschstein D, Ho W, Hupp M, Jarsky T, Johansen N, Kalmbach BE, Keene LM, Khawand S, Kilgore MD, Kirkland A, Kunst M, Lee BR, Leytze M, Mac Donald CL, Malone J, Maltzer Z, Martin N, McCue R, McMillen D, Mena G, Meyerdierks E, Meyers KP, Mollenkopf T, Montine M, Nolan AL, Nyhus JK, Olsen PA, Pacleb M, Pagan CM, Peña N, Pham T, Pom CA, Postupna N, Rimorin C, Ruiz A, Saldi GA, Schantz AM, Shapovalova NV, Sorensen SA, Staats B, Sullivan M, Sunkin SM, Thompson C, Tieu M, Ting JT, Torkelson A, Tran T, Valera Cuevas NJ, Walling-Bell S, Wang MQ, Waters J, Wilson AM, Xiao M, Haynor D, Gatto NM, Jayadev S, Mufti S, Ng L, Mukherjee S, Crane PK, Latimer CS, Levi BP, Smith KA, Close JL, Miller JA, Hodge RD, Larson EB, Grabowski TJ, Hawrylycz M, Keene CD, Lein ES Nature neuroscience 39402379 Nat Neurosci 2024 Dec
Assays to measure small molecule Hsp70 agonist activity in vitro and in vivo. Shapiro O, Woods C, Gleixner AM, Sannino S, Ngo M, McDaniels MD, Wipf P, Hukriede NA, Donnelly CJ, Brodsky JL Analytical biochemistry 39522672 Anal Biochem 2025 Feb
Disrupting pathologic phase transitions in neurodegeneration. Hurtle BT, Xie L, Donnelly CJ The Journal of clinical investigation 37395272 J Clin Invest 2023 Jul 3
A polygenic score method boosted by non-additive models. Ohta R, Tanigawa Y, Suzuki Y, Kellis M, Morishita S Nature communications 38811555 Nat Commun 2024 May 29
How it feels in a cell. Bonucci M, Shu T, Holt LJ Trends in cell biology 37286396 Trends Cell Biol 2023 Nov
Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death. Aber ER, Griffey CJ, Davies T, Li AM, Yang YJ, Croce KR, Goldman JE, Grutzendler J, Canman JC, Yamamoto A Cell reports 36261002 Cell Rep 2022 Oct 18
Amygdala TDP-43 pathology is associated with behavioural dysfunction and ferritin accumulation in amyotrophic lateral sclerosis. Rifai OM, Waldron FM, O'Shaughnessy J, Read FL, Gilodi M, Pastore A, Shneider N, Tartaglia GG, Zacco E, Spence H, Gregory JM bioRxiv : the preprint server for biology 38854008 bioRxiv 2024 Jun 1
Adult-onset deactivation of autophagy leads to loss of synapse homeostasis and cognitive impairment, with implications for alzheimer disease. Grosso Jasutkar H, Wasserlein EM, Ishola A, Litt N, Staniszewski A, Arancio O, Yamamoto A Autophagy 38949671 Autophagy 2024 Nov
Polysome collapse and RNA condensation fluidize the cytoplasm. Xie Y, Shu T, Liu T, Spindler MC, Mahamid J, Hocky GM, Gresham D, Holt LJ Molecular cell 39059370 Mol Cell 2024 Jul 25
Phase Separation in Biology and Disease; Current Perspectives and Open Questions. Boeynaems S, Chong S, Gsponer J, Holt L, Milovanovic D, Mitrea DM, Mueller-Cajar O, Portz B, Reilly JF, Reinkemeier CD, Sabari BR, Sanulli S, Shorter J, Sontag E, Strader L, Stachowiak J, Weber SC, White M, Zhang H, Zweckstetter M, Elbaum-Garfinkle S, Kriwacki R Journal of molecular biology 36690068 J Mol Biol 2023 Mar 1
Macromolecular crowding: Sensing without a sensor. Holt LJ, Delarue M Current opinion in cell biology 37897928 Curr Opin Cell Biol 2023 Dec
Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates. Saleeb RS, Leighton C, Lee JE, O'Shaughnessy J, Jeacock K, Chappard A, Cumberland R, Zhao T, Ball SR, Sunde M, Clarke DJ, Piché K, McPhail JA, Louwrier A, Angers R, Gandhi S, Downey P, Kunath T, Horrocks MH Science advances 37967183 Sci Adv 2023 Nov 17
Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live Escherichia coli cells. Valverde-Mendez D, Sunol AM, Bratton BP, Delarue M, Hofmann JL, Sheehan JP, Gitai Z, Holt LJ, Shaevitz JW, Zia RN bioRxiv : the preprint server for biology 38585850 bioRxiv 2024 Mar 28
Development and Characterization of 50 nanometer diameter Genetically Encoded Multimeric Nanoparticles. Hernandez CM, Duran-Chaparro DC, van Eeuwen T, Rout MP, Holt LJ bioRxiv : the preprint server for biology 39005449 bioRxiv 2024 Jul 7
The broken Alzheimer's disease genome. Gouveia Roque C, Phatnani H, Hengst U Cell genomics 38697121 Cell Genom 2024 May 8
Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions. Devany J, Falk MJ, Holt LJ, Murugan A, Gardel ML Developmental cell 37339629 Dev Cell 2023 Aug 21
A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis. Shi J, Wu X, Wang Z, Li F, Meng Y, Moore RM, Cui J, Xue C, Croce KR, Yurdagul A Jr, Doench JG, Li W, Zarbalis KS, Tabas I, Yamamoto A, Zhang H Nature communications 36566259 Nat Commun 2022 Dec 24
Increased mesoscale diffusivity in response to acute glucose starvation. Xie Y, Gresham D, Holt L bioRxiv : the preprint server for biology 36711511 bioRxiv 2023 Jan 12
Controlling the crowd with a WNK. Holt LJ, Denes LT Cell 36423576 Cell 2022 Nov 23
Mesoscale molecular assembly is favored by the active, crowded cytoplasm. Shu T, Mitra G, Alberts J, Viana MP, Levy ED, Hocky GM, Holt LJ bioRxiv : the preprint server for biology 37781612 bioRxiv 2023 Sep 21
Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts. Rifai OM, O'Shaughnessy J, Dando OR, Munro AF, Sewell MDE, Abrahams S, Waldron FM, Sibley CR, Gregory JM Brain : a journal of neurology 37450566 Brain 2023 Dec 1
Condensation of LINE-1 is critical for retrotransposition. Sil S, Keegan S, Ettefa F, Denes LT, Boeke JD, Holt LJ eLife 37114770 Elife 2023 Apr 28
Macromolecular crowding limits growth under pressure. Alric B, Formosa-Dague C, Dague E, Holt LJ, Delarue M Nature physics 37152719 Nat Phys 2022 Apr
Increased mesoscale diffusivity in response to acute glucose starvation. Xie Y, Gresham D, Holt LJ microPublication biology 36908311 MicroPubl Biol 2023
Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding. Sang D, Shu T, Pantoja CF, Ibáñez de Opakua A, Zweckstetter M, Holt LJ Molecular cell 36108633 Mol Cell 2022 Oct 6
Autophagy at the synapse, an early site of dysfunction in neurodegeneration. Jasutkar HG, Yamamoto A Current opinion in physiology 36968133 Curr Opin Physiol 2023 Apr
mRNA condensation fluidizes the cytoplasm. Xie Y, Liu T, Gresham D, Holt LJ bioRxiv : the preprint server for biology 37398029 bioRxiv 2023 Jul 15
The environmental stress response regulates ribosome content in cell cycle-arrested S. cerevisiae. Terhorst A, Sandikci A, Whittaker CA, Szórádi T, Holt LJ, Neurohr GE, Amon A Frontiers in cell and developmental biology 37123399 Front Cell Dev Biol 2023
RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS. Spence H, Waldron FM, Saleeb RS, Brown AL, Rifai OM, Gilodi M, Read F, Roberts K, Milne G, Wilkinson D, O'Shaughnessy J, Pastore A, Fratta P, Shneider N, Tartaglia GG, Zacco E, Horrocks MH, Gregory JM Acta neuropathologica 38443601 Acta Neuropathol 2024 Mar 5
Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis. Rifai OM, Waldron FM, Sleibi D, O'Shaughnessy J, Leighton DJ, Gregory JM Brain pathology (Zurich, Switzerland) 38986433 Brain Pathol 2025 Jan
Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live Escherichia coli cells. Valverde-Mendez D, Sunol AM, Bratton BP, Delarue M, Hofmann JL, Sheehan JP, Gitai Z, Holt LJ, Shaevitz JW, Zia RN Proceedings of the National Academy of Sciences of the United States of America 39854229 Proc Natl Acad Sci U S A 2025 Jan 28
Machine learning identifies routine blood tests as accurate predictive measures of pollution-dependent poor cognitive function. Johnson H, Longden J, Cameron G, Waiter GD, Waldron FM, Gregory JM, Spence H bioRxiv : the preprint server for biology 39868217 bioRxiv 2025 Jan 13
Stem cell transcriptional profiles from mouse subspecies reveal cis -regulatory evolution at translation genes. Simon NM, Kim Y, Bautista DM, Dutton JR, Brem RB bioRxiv : the preprint server for biology 37503246 bioRxiv 2024 Jul 20
SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain. Mali SS, Silva R, Gong Z, Cronce M, Vo U, Vuong C, Moayedi Y, Cox JS, Bautista DM bioRxiv : the preprint server for biology 38260476 bioRxiv 2024 Jan 11
Basophils add fuel to the flame of eczema itch. Mali SS, Bautista DM Cell 33482094 Cell 2021 Jan 21
Avid lysosomal acidification in fibroblasts of the Mediterranean mouse Mus spretus. Sui M, Teh J, Fort K, Shaw D, Sudmant P, Koide T, Good JM, Vazquez JM, Brem RB bioRxiv : the preprint server for biology 39974907 bioRxiv 2025 Feb 7
Stem cell transcriptional profiles from mouse subspecies reveal cis-regulatory evolution at translation genes. Simon NM, Kim Y, Gribnau J, Bautista DM, Dutton JR, Brem RB Heredity 39164520 Heredity (Edinb) 2024 Nov
Expanding the AtLAS of non-coding RNA functions in the brain. Regier MJ, Shepherd JD Cell research 32111970 Cell Res 2020 Apr
Arc mediates intercellular tau transmission via extracellular vesicles. Tyagi M, Chadha R, de Hoog E, Sullivan KR, Walker AC, Northrop A, Fabian B, Fuxreiter M, Hyman BT, Shepherd JD bioRxiv : the preprint server for biology 39484489 bioRxiv 2024 Oct 22
PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome. Xu J, Erlendsson S, Singh M, Regier M, Ibiricu I, Day GS, Piquet AL, Clardy SL, Feschotte C, Briggs JAG, Shepherd JD bioRxiv : the preprint server for biology 36798413 bioRxiv 2023 Feb 9
PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome. Xu J, Erlendsson S, Singh M, Holling GA, Regier M, Ibiricu I, Einstein J, Hantak MP, Day GS, Piquet AL, Smith TL, Clardy SL, Whiteley AM, Feschotte C, Briggs JAG, Shepherd JD Cell 38301645 Cell 2024 Feb 15
The mammalian midbody and midbody remnant are assembly sites for RNA and localized translation. Park S, Dahn R, Kurt E, Presle A, VanDenHeuvel K, Moravec C, Jambhekar A, Olukoga O, Shepherd J, Echard A, Blower M, Skop AR Developmental cell 37552987 Dev Cell 2023 Oct 9
Intercellular Arc Signaling Regulates Vasodilation. de la Peña JB, Barragan-Iglesias P, Lou TF, Kunder N, Loerch S, Shukla T, Basavarajappa L, Song J, James DN, Megat S, Moy JK, Wanghzou A, Ray PR, Hoyt K, Steward O, Price TJ, Shepherd J, Campbell ZT The Journal of neuroscience : the official journal of the Society for Neuroscience 34326146 J Neurosci 2021 Sep 15
Intercellular Communication in the Nervous System Goes Viral. Hantak MP, Einstein J, Kearns RB, Shepherd JD Trends in neurosciences 33485691 Trends Neurosci 2021 Apr
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Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma. Darmanis S, Sloan SA, Croote D, Mignardi M, Chernikova S, Samghababi P, Zhang Y, Neff N, Kowarsky M, Caneda C, Li G, Chang SD, Connolly ID, Li Y, Barres BA, Gephart MH, Quake SR Cell reports 29091775 Cell Rep 2017 Oct 31
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Imaging ATUM ultrathin section libraries with WaferMapper: a multi-scale approach to EM reconstruction of neural circuits. Hayworth KJ, Morgan JL, Schalek R, Berger DR, Hildebrand DG, Lichtman JW Frontiers in neural circuits 25018701 Front Neural Circuits 2014
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Digital Museum of Retinal Ganglion Cells with Dense Anatomy and Physiology. Bae JA, Mu S, Kim JS, Turner NL, Tartavull I, Kemnitz N, Jordan CS, Norton AD, Silversmith WM, Prentki R, Sorek M, David C, Jones DL, Bland D, Sterling ALR, Park J, Briggman KL, Seung HS, Eyewirers Cell 29775596 Cell 2018 May 17
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Developmental Rewiring between Cerebellar Climbing Fibers and Purkinje Cells Begins with Positive Feedback Synapse Addition. Wilson AM, Schalek R, Suissa-Peleg A, Jones TR, Knowles-Barley S, Pfister H, Lichtman JW Cell reports 31775050 Cell Rep 2019 Nov 26
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Neural Circuit Inference from Function to Structure. Real E, Asari H, Gollisch T, Meister M Current biology : CB 28065610 Curr Biol 2017 Jan 23
Analogous Convergence of Sustained and Transient Inputs in Parallel On and Off Pathways for Retinal Motion Computation. Greene MJ, Kim JS, Seung HS, EyeWirers Cell reports 26904938 Cell Rep 2016 Mar 1
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Design and Evaluation of Interactive Proofreading Tools for Connectomics. Haehn D, Knowles-Barley S, Roberts M, Beyer J, Kasthuri N, Lichtman JW, Pfister H IEEE transactions on visualization and computer graphics 26356960 IEEE Trans Vis Comput Graph 2014 Dec
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles. Akalin A, Kormaksson M, Li S, Garrett-Bakelman FE, Figueroa ME, Melnick A, Mason CE Genome biology 23034086 Genome Biol 2012 Oct 3
Antiepileptic drugs and pregnancy outcomes. Wlodarczyk BJ, Palacios AM, George TM, Finnell RH American journal of medical genetics. Part A 22711424 Am J Med Genet A 2012 Aug
Assessment of pharmacogenomic agreement. Safikhani Z, El-Hachem N, Quevedo R, Smirnov P, Goldenberg A, Juul Birkbak N, Mason C, Hatzis C, Shi L, Aerts HJ, Quackenbush J, Haibe-Kains B F1000Research 27408686 F1000Res 2016
The Microbe Directory: An annotated, searchable inventory of microbes' characteristics. Shaaban H, Westfall DA, Mohammad R, Danko D, Bezdan D, Afshinnekoo E, Segata N, Mason CE Gates open research 29630066 Gates Open Res 2018 Jan 5
The Impact of Heterogeneity on Single-Cell Sequencing. Goldman SL, MacKay M, Afshinnekoo E, Melnick AM, Wu S, Mason CE Frontiers in genetics 30881372 Front Genet 2019
Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain. Nandi S, Chandramohan D, Fioriti L, Melnick AM, Hébert JM, Mason CE, Rajasethupathy P, Kandel ER Proceedings of the National Academy of Sciences of the United States of America 27791114 Proc Natl Acad Sci U S A 2016 Nov 8
Complex translocation disrupting TCF4 and altering TCF4 isoform expression segregates as mild autosomal dominant intellectual disability. Maduro V, Pusey BN, Cherukuri PF, Atkins P, du Souich C, Rupps R, Limbos M, Adams DR, Bhatt SS, Eydoux P, Links AE, Lehman A, Malicdan MC, Mason CE, Morimoto M, Mullikin JC, Sear A, Van Karnebeek C, Stankiewicz P, Gahl WA, Toro C, Boerkoel CF Orphanet journal of rare diseases 27179618 Orphanet J Rare Dis 2016 May 14
Epigenetic therapy in a new era of medicine: creating and integrating molecular profiles of patients. Afshinnekoo E, Mason CE Annals of translational medicine 27942527 Ann Transl Med 2016 Nov
Assessment of REPLI-g Multiple Displacement Whole Genome Amplification (WGA) Techniques for Metagenomic Applications. Ahsanuddin S, Afshinnekoo E, Gandara J, Hakyemezoğlu M, Bezdan D, Minot S, Greenfield N, Mason CE Journal of biomolecular techniques : JBT 28344519 J Biomol Tech 2017 Apr
Two methods for full-length RNA sequencing for low quantities of cells and single cells. Pan X, Durrett RE, Zhu H, Tanaka Y, Li Y, Zi X, Marjani SL, Euskirchen G, Ma C, Lamotte RH, Park IH, Snyder MP, Mason CE, Weissman SM Proceedings of the National Academy of Sciences of the United States of America 23267071 Proc Natl Acad Sci U S A 2013 Jan 8
The non-human primate reference transcriptome resource (NHPRTR) for comparative functional genomics. Pipes L, Li S, Bozinoski M, Palermo R, Peng X, Blood P, Kelly S, Weiss JM, Thierry-Mieg J, Thierry-Mieg D, Zumbo P, Chen R, Schroth GP, Mason CE, Katze MG Nucleic acids research 23203872 Nucleic Acids Res 2013 Jan
The continuing challenge of understanding, preventing, and treating neural tube defects. Wallingford JB, Niswander LA, Shaw GM, Finnell RH Science (New York, N.Y.) 23449594 Science 2013 Mar 1
Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome. Linder B, Grozhik AV, Olarerin-George AO, Meydan C, Mason CE, Jaffrey SR Nature methods 26121403 Nat Methods 2015 Aug
Analysis of archived residual newborn screening blood spots after whole genome amplification. Cantarel BL, Lei Y, Weaver D, Zhu H, Farrell A, Benstead-Hume G, Reese J, Finnell RH BMC genomics 26268606 BMC Genomics 2015 Aug 13
Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution. Garrett-Bakelman FE, Sheridan CK, Kacmarczyk TJ, Ishii J, Betel D, Alonso A, Mason CE, Figueroa ME, Melnick AM Journal of visualized experiments : JoVE 25742437 J Vis Exp 2015 Feb 24
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia. Shih AH, Jiang Y, Meydan C, Shank K, Pandey S, Barreyro L, Antony-Debre I, Viale A, Socci N, Sun Y, Robertson A, Cavatore M, de Stanchina E, Hricik T, Rapaport F, Woods B, Wei C, Hatlen M, Baljevic M, Nimer SD, Tallman M, Paietta E, Cimmino L, Aifantis I, Steidl U, Mason C, Melnick A, Levine RL Cancer cell 25873173 Cancer Cell 2015 Apr 13
Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius. Rosenfeld JA, Reeves D, Brugler MR, Narechania A, Simon S, Durrett R, Foox J, Shianna K, Schatz MC, Gandara J, Afshinnekoo E, Lam ET, Hastie AR, Chan S, Cao H, Saghbini M, Kentsis A, Planet PJ, Kholodovych V, Tessler M, Baker R, DeSalle R, Sorkin LN, Kolokotronis SO, Siddall ME, Amato G, Mason CE Nature communications 26836631 Nat Commun 2016 Feb 2
Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Tabler JM, Barrell WB, Szabo-Rogers HL, Healy C, Yeung Y, Perdiguero EG, Schulz C, Yannakoudakis BZ, Mesbahi A, Wlodarczyk B, Geissmann F, Finnell RH, Wallingford JB, Liu KJ Developmental cell 23806618 Dev Cell 2013 Jun 24
Neural tube defects, folate, and immune modulation. Denny KJ, Jeanes A, Fathe K, Finnell RH, Taylor SM, Woodruff TM Birth defects research. Part A, Clinical and molecular teratology 24078477 Birth Defects Res A Clin Mol Teratol 2013 Sep
Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers. Ricarte-Filho JC, Li S, Garcia-Rendueles ME, Montero-Conde C, Voza F, Knauf JA, Heguy A, Viale A, Bogdanova T, Thomas GA, Mason CE, Fagin JA The Journal of clinical investigation 24135138 J Clin Invest 2013 Nov
An optimized algorithm for detecting and annotating regional differential methylation. Li S, Garrett-Bakelman FE, Akalin A, Zumbo P, Levine R, To BL, Lewis ID, Brown AL, D'Andrea RJ, Melnick A, Mason CE BMC bioinformatics 23735126 BMC Bioinformatics 2013
Tissue-specific transcriptome sequencing analysis expands the non-human primate reference transcriptome resource (NHPRTR). Peng X, Thierry-Mieg J, Thierry-Mieg D, Nishida A, Pipes L, Bozinoski M, Thomas MJ, Kelly S, Weiss JM, Raveendran M, Muzny D, Gibbs RA, Rogers J, Schroth GP, Katze MG, Mason CE Nucleic acids research 25392405 Nucleic Acids Res 2015 Jan
Identification of novel CELSR1 mutations in spina bifida. Lei Y, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH PloS one 24632739 PLoS One 2014
High-throughput RNA sequencing reveals structural differences of orthologous brain-expressed genes between western lowland gorillas and humans. Lipovich L, Hou ZC, Jia H, Sinkler C, McGowen M, Sterner KN, Weckle A, Sugalski AB, Pipes L, Gatti DL, Mason CE, Sherwood CC, Hof PR, Kuzawa CW, Grossman LI, Goodman M, Wildman DE The Journal of comparative neurology 26132897 J Comp Neurol 2016 Feb 1
The birth of the Epitranscriptome: deciphering the function of RNA modifications. Saletore Y, Meyer K, Korlach J, Vilfan ID, Jaffrey S, Mason CE Genome biology 23113984 Genome Biol 2012 Oct 31
A GCH1 haplotype and risk of neural tube defects in the National Birth Defects Prevention Study. Lupo PJ, Chapa C, Nousome D, Duhon C, Canfield MA, Shaw GM, Finnell RH, Zhu H, National Birth Defects Prevention Study Molecular genetics and metabolism 23059057 Mol Genet Metab 2012 Nov
Assessment and improvement of Indian-origin rhesus macaque and Mauritian-origin cynomolgus macaque genome annotations using deep transcriptome sequencing data. Peng X, Pipes L, Xiong H, Green RR, Jones DC, Ruzzo WL, Schroth GP, Mason CE, Palermo RE, Katze MG Journal of medical primatology 24810475 J Med Primatol 2014 Oct
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J, Li Y, Ahn J, Abdel-Wahab O, Shih A, Lu C, Ward PS, Tsai JJ, Hricik T, Tosello V, Tallman JE, Zhao X, Daniels D, Dai Q, Ciminio L, Aifantis I, He C, Fuks F, Tallman MS, Ferrando A, Nimer S, Paietta E, Thompson CB, Licht JD, Mason CE, Godley LA, Melnick A, Figueroa ME, Levine RL Cell reports 25482556 Cell Rep 2014 Dec 11
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia. Shih AH, Meydan C, Shank K, Garrett-Bakelman FE, Ward PS, Intlekofer AM, Nazir A, Stein EM, Knapp K, Glass J, Travins J, Straley K, Gliser C, Mason CE, Yen K, Thompson CB, Melnick A, Levine RL Cancer discovery 28193779 Cancer Discov 2017 May
Clinical Genomics: Challenges and Opportunities. Vijay P, McIntyre AB, Mason CE, Greenfield JP, Li S Critical reviews in eukaryotic gene expression 27480773 Crit Rev Eukaryot Gene Expr 2016
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia. Li S, Garrett-Bakelman FE, Chung SS, Sanders MA, Hricik T, Rapaport F, Patel J, Dillon R, Vijay P, Brown AL, Perl AE, Cannon J, Bullinger L, Luger S, Becker M, Lewis ID, To LB, Delwel R, Löwenberg B, Döhner H, Döhner K, Guzman ML, Hassane DC, Roboz GJ, Grimwade D, Valk PJ, D'Andrea RJ, Carroll M, Park CY, Neuberg D, Levine R, Melnick AM, Mason CE Nature medicine 27322744 Nat Med 2016 Jul
Genomic Methods and Microbiological Technologies for Profiling Novel and Extreme Environments for the Extreme Microbiome Project (XMP). Tighe S, Afshinnekoo E, Rock TM, McGrath K, Alexander N, McIntyre A, Ahsanuddin S, Bezdan D, Green SJ, Joye S, Stewart Johnson S, Baldwin DA, Bivens N, Ajami N, Carmical JR, Herriott IC, Colwell R, Donia M, Foox J, Greenfield N, Hunter T, Hoffman J, Hyman J, Jorgensen E, Krawczyk D, Lee J, Levy S, Garcia-Reyero N, Settles M, Thomas K, Gómez F, Schriml L, Kyrpides N, Zaikova E, Penterman J, Mason CE Journal of biomolecular techniques : JBT 28337070 J Biomol Tech 2017 Apr
N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Gokhale NS, McIntyre ABR, McFadden MJ, Roder AE, Kennedy EM, Gandara JA, Hopcraft SE, Quicke KM, Vazquez C, Willer J, Ilkayeva OR, Law BA, Holley CL, Garcia-Blanco MA, Evans MJ, Suthar MS, Bradrick SS, Mason CE, Horner SM Cell host & microbe 27773535 Cell Host Microbe 2016 Nov 9
Genetic and epigenetic heterogeneity in acute myeloid leukemia. Li S, Mason CE, Melnick A Current opinion in genetics & development 27162099 Curr Opin Genet Dev 2016 Feb
Extensive sequencing of seven human genomes to characterize benchmark reference materials. Zook JM, Catoe D, McDaniel J, Vang L, Spies N, Sidow A, Weng Z, Liu Y, Mason CE, Alexander N, Henaff E, McIntyre AB, Chandramohan D, Chen F, Jaeger E, Moshrefi A, Pham K, Stedman W, Liang T, Saghbini M, Dzakula Z, Hastie A, Cao H, Deikus G, Schadt E, Sebra R, Bashir A, Truty RM, Chang CC, Gulbahce N, Zhao K, Ghosh S, Hyland F, Fu Y, Chaisson M, Xiao C, Trow J, Sherry ST, Zaranek AW, Ball M, Bobe J, Estep P, Church GM, Marks P, Kyriazopoulou-Panagiotopoulou S, Zheng GX, Schnall-Levin M, Ordonez HS, Mudivarti PA, Giorda K, Sheng Y, Rypdal KB, Salit M Scientific data 27271295 Sci Data 2016 Jun 7
Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity. Goldman SL, Hassan C, Khunte M, Soldatenko A, Jong Y, Afshinnekoo E, Mason CE Frontiers in genetics 30881380 Front Genet 2019
New Techniques for the Study of Neural Tube Defects. Lei Y, Finnell RH Advanced techniques in biology & medicine 27066597 Adv Tech Biol Med 2016 Feb
Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects. Denny KJ, Kelly CF, Kumar V, Witham KL, Cabrera RM, Finnell RH, Taylor SM, Jeanes A, Woodruff TM Birth defects research. Part A, Clinical and molecular teratology 26900104 Birth Defects Res A Clin Mol Teratol 2016 Mar
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. SEQC/MAQC-III Consortium Nature biotechnology 25150838 Nat Biotechnol 2014 Sep
Dynamic evolution of clonal epialleles revealed by methclone. Li S, Garrett-Bakelman F, Perl AE, Luger SM, Zhang C, To BL, Lewis ID, Brown AL, D'Andrea RJ, Ross ME, Levine R, Carroll M, Melnick A, Mason CE Genome biology 25260792 Genome Biol 2014 Sep 27
Rare LRP6 variants identified in spina bifida patients. Lei Y, Fathe K, McCartney D, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH Human mutation 25546815 Hum Mutat 2015 Mar
Nanopore sequencing in microgravity. McIntyre ABR, Rizzardi L, Yu AM, Alexander N, Rosen GL, Botkin DJ, Stahl SE, John KK, Castro-Wallace SL, McGrath K, Burton AS, Feinberg AP, Mason CE NPJ microgravity 28725742 NPJ Microgravity 2016
Single-molecule sequencing detection of N6-methyladenine in microbial reference materials. McIntyre ABR, Alexander N, Grigorev K, Bezdan D, Sichtig H, Chiu CY, Mason CE Nature communications 30718479 Nat Commun 2019 Feb 4
Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity. Gertz ML, Chin CR, Tomoiaga D, MacKay M, Chang C, Butler D, Afshinnekoo E, Bezdan D, Schmidt MA, Mozsary C, Melnick A, Garrett-Bakelman F, Crucian B, Lee SMC, Zwart SR, Smith SM, Meydan C, Mason CE Cell reports 33242408 Cell Rep 2020 Dec 8
Rfx2 is required for spermatogenesis in the mouse. Shawlot W, Vazquez-Chantada M, Wallingford JB, Finnell RH Genesis (New York, N.Y. : 2000) 26248850 Genesis 2015 Sep
Characterization of the public transit air microbiome and resistome reveals geographical specificity. Leung MHY, Tong X, Bøifot KO, Bezdan D, Butler DJ, Danko DC, Gohli J, Green DC, Hernandez MT, Kelly FJ, Levy S, Mason-Buck G, Nieto-Caballero M, Syndercombe-Court D, Udekwu K, Young BG, Mason CE, Dybwad M, Lee PKH Microbiome 34039416 Microbiome 2021 May 26
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood. Ng DL, Granados AC, Santos YA, Servellita V, Goldgof GM, Meydan C, Sotomayor-Gonzalez A, Levine AG, Balcerek J, Han LM, Akagi N, Truong K, Neumann NM, Nguyen DN, Bapat SP, Cheng J, Martin CS, Federman S, Foox J, Gopez A, Li T, Chan R, Chu CS, Wabl CA, Gliwa AS, Reyes K, Pan CY, Guevara H, Wadford D, Miller S, Mason CE, Chiu CY Science advances 33536218 Sci Adv 2021 Feb
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Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury. Blaya MO, Bramlett HM, Naidoo J, Pieper AA, Dietrich WD Journal of neurotrauma 24070637 J Neurotrauma 2014 Mar 1
Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties. Naidoo J, De Jesus-Cortes H, Huntington P, Estill S, Morlock LK, Starwalt R, Mangano TJ, Williams NS, Pieper AA, Ready JM Journal of medicinal chemistry 24697290 J Med Chem 2014 May 8
Identification of small molecule antagonists of sonic hedgehog/heparin binding with activity in hedgehog functional assays. Lamson DR, Tarpley M, Addo K, Ji X, Abu Rabe D, Ehe B, Hughes M, Smith GR, Daye LR, Musso DL, Zheng W, Williams KP Biochimica et biophysica acta. General subjects 39151833 Biochim Biophys Acta Gen Subj 2024 Nov
Population-enriched innate immune variants may identify candidate gene targets at the intersection of cancer and cardio-metabolic disease. Yeyeodu S, Hanafi D, Webb K, Laurie NA, Kimbro KS Frontiers in endocrinology 38577257 Front Endocrinol (Lausanne) 2023
Geospatial Associations between Female Breast Cancer Mortality Rates and Environmental Socioeconomic Indicators for North Carolina. Burwell A, Kimbro S, Mulrooney T International journal of environmental research and public health 37510605 Int J Environ Res Public Health 2023 Jul 15
Identification of Novel GANT61 Analogs with Activity in Hedgehog Functional Assays and GLI1-Dependent Cancer Cells. Abu Rabe D, Chdid L, Lamson DR, Laudeman CP, Tarpley M, Elsayed N, Smith GR, Zheng W, Dixon MS, Williams KP Molecules (Basel, Switzerland) 38999049 Molecules 2024 Jun 28
Applying a Gene Reversal Rate Computational Methodology to Identify Drugs for a Rare Cancer: Inflammatory Breast Cancer. Ji X, Williams KP, Zheng W Cancer informatics 37846218 Cancer Inform 2023
Study protocol for transforming health equity research in integrated primary care: Antiracism as a disruptive innovation. Naar S, Pettus C, Anderson N, Pooler-Burgess M, Ralston P, Flynn H, Combs T, Baquet C, Schatschneider C, Luke D PloS one 38935743 PLoS One 2024
Interventions Across the Translational Research Spectrum: Addressing Disparities Among Racial and Ethnic Minoritized Youth with Type 1 Diabetes. Ellis DA, Naar S Endocrinology and metabolism clinics of North America 37865475 Endocrinol Metab Clin North Am 2023 Dec
A look at the increasing demographic representation within behavioral medicine. Yoon S, Falzon L, Anderson NB, Davidson KW Journal of behavioral medicine 30825089 J Behav Med 2019 Feb
Effectiveness of interventions targeting self-regulation to improve adherence to chronic disease medications: a meta-review of meta-analyses. Wilson TE, Hennessy EA, Falzon L, Boyd R, Kronish IM, Birk JL Health psychology review 31856664 Health Psychol Rev 2020 Mar
Intubated COVID-19 predictive (ICOP) score for early mortality after intubation in patients with COVID-19. Nishikimi M, Rasul R, Sison CP, Jafari D, Shoaib M, Shinozaki K, Li T, Hayashida K, Rolston DM, Hirsch JS, Becker LB, Northwell Health COVID-19 Research Consortium Scientific reports 34702896 Sci Rep 2021 Oct 26
Examination of patient characteristics and hydroxychloroquine use based on the US Food and Drug Administration's recommendation: a cross-sectional analysis in New York. Kim EJ, Coppa K, Hirsch JS, Abrahams S, Johnson J, Lesser M, Davidson KW, Conigliaro J, Northwell Health COVID-19 Research Consortium, Northwell Health COVID-19 Research Consortium BMJ open 33558355 BMJ Open 2021 Feb 8
Accomplishing breakthroughs in behavioural medicine research. Davidson KW, Bacon SL, Bennett GG, Brondolo E, Czajkowski SM, Diefenbach MA, Epel ES, Matthews K, Revenson TA, Ruiz JM, Segerstrom SC, Behavioral Medicine Research Council Nature human behaviour 34127817 Nat Hum Behav 2021 Jul
Mortality of Mechanically Ventilated COVID-19 Patients in Traditional versus Expanded Intensive Care Units in New York. Nishikimi M, Jafari D, Singh N, Shinozaki K, Sison CP, Shoaib M, Gong J, Rasul R, Li T, Hayashida K, Rolston DM, Miyara SJ, Hirsch JS, Gandomi A, White MT, Jarrett MP, Lesser ML, Becker LB, Northwell Health COVID-19 Research Consortium Annals of the American Thoracic Society 35213292 Ann Am Thorac Soc 2022 Aug
Now is the time to assess the effects of open science practiceswith randomized control trials. Suls J, Rothman AJ, Davidson KW The American psychologist 34807632 Am Psychol 2022 Apr
Envisioning a future for precision health psychology: innovative applied statistical approaches to N-of-1 studies. Davidson KW, Cheung YK Health psychology review 28651455 Health Psychol Rev 2017 Sep
Are Nomothetic or Ideographic Approaches Superior in Predicting Daily Exercise Behaviors? Cheung YK, Hsueh PS, Qian M, Yoon S, Meli L, Diaz KM, Schwartz JE, Kronish IM, Davidson KW Methods of information in medicine 29582914 Methods Inf Med 2017
Clinical Usefulness of Bright White Light Therapy for Depressive Symptoms in Cancer Survivors: Results from a Series of Personalized (N-of-1) Trials. Kronish IM, Cheung YK, Julian J, Parsons F, Lee J, Yoon S, Valdimarsdottir H, Green P, Suls J, Hershman DL, Davidson KW Healthcare (Basel, Switzerland) 31905890 Healthcare (Basel) 2019 Dec 30
Effectiveness of SARS-CoV-2 Decontamination and Containment in a COVID-19 ICU. Brune Z, Kuschner CE, Mootz J, Davidson KW, Pena RCF, Ghanem MH, Fischer A, Gitman M, Teperman L, Mason C, Becker LB International journal of environmental research and public health 33802332 Int J Environ Res Public Health 2021 Mar 3
Prevalence and Predictors of Venous Thromboembolism or Mortality in Hospitalized COVID-19 Patients. Cohen SL, Gianos E, Barish MA, Chatterjee S, Kohn N, Lesser M, Giannis D, Coppa K, Hirsch JS, McGinn TG, Goldin ME, Spyropoulos AC, Northwell Health COVID-19 Research Consortium Thrombosis and haemostasis 33472255 Thromb Haemost 2021 Aug
A Machine Learning Prediction Model of Respiratory Failure Within 48 Hours of Patient Admission for COVID-19: Model Development and Validation. Bolourani S, Brenner M, Wang P, McGinn T, Hirsch JS, Barnaby D, Zanos TP, Northwell COVID-19 Research Consortium Journal of medical Internet research 33476281 J Med Internet Res 2021 Feb 10
Rapid Emergence of SARS-CoV-2 in the Greater New York Metropolitan Area: Geolocation, Demographics, Positivity Rates, and Hospitalization for 46 793 Persons Tested by Northwell Health. Reichberg SB, Mitra PP, Haghamad A, Ramrattan G, Crawford JM, Northwell COVID-19 Research Consortium, Berry GJ, Davidson KW, Drach A, Duong S, Juretschko S, Maria NI, Yang Y, Ziemba YC Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 32640030 Clin Infect Dis 2020 Dec 15
Series of virtual light therapy interventions for fatigue: a feasibility pilot study protocol for a series of personalised (N-of-1) trials. Butler M, D'Angelo S, Lewis C, Miller D, Perrin A, Suls J, Chandereng T, Cheung YK, Davidson KW BMJ open 36283748 BMJ Open 2022 Oct 25
Scientific opportunities in resilience research for cardiovascular health and wellness. Report from a National Heart, Lung, and Blood Institute workshop. Taylor HA, Finkel T, Gao Y, Ballinger SW, Campo R, Chen R, Chen SH, Davidson K, Iruela-Arispe ML, Jaquish C, LeBrasseur NK, Odden MC, Papanicolaou GJ, Picard M, Srinivas P, Tjurmina O, Wolz M, Galis ZS FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36322029 FASEB J 2022 Dec
Why Do I Get Side Effects? Personalized (N-of-1) Trials for Statin Intolerance and the Nocebo Effect. Howard JP, Wood FA, Francis DP Harvard data science review 38344133 Harv Data Sci Rev 2022
A Series of Remote Melatonin Supplement Interventions for Poor Sleep: Protocol for a Feasibility Pilot Study for a Series of Personalized (N-of-1) Trials. Butler M, D'Angelo S, Perrin A, Rodillas J, Miller D, Arader L, Chandereng T, Cheung YK, Shechter A, Davidson KW JMIR research protocols 37535419 JMIR Res Protoc 2023 Aug 3
Protocol for randomized personalized trial for stress management compared to standard of care. Goodwin AM, Miller D, D'Angelo S, Perrin A, Wiener R, Greene B, Romain AN, Arader L, Chandereng T, Kuen Cheung Y, Davidson KW, Butler M Frontiers in psychology 37794909 Front Psychol 2023
Using Behavioral Analytics to Increase Exercise: A Randomized N-of-1 Study. Yoon S, Schwartz JE, Burg MM, Kronish IM, Alcantara C, Julian J, Parsons F, Davidson KW, Diaz KM American journal of preventive medicine 29429607 Am J Prev Med 2018 Apr
Increasing the Precision of Hypertension Treatment Through Personalized Trials: a Pilot Study. Kronish IM, Cheung YK, Shimbo D, Julian J, Gallagher B, Parsons F, Davidson KW Journal of general internal medicine 30859504 J Gen Intern Med 2019 Jun
Selected psychological comorbidities in coronary heart disease: Challenges and grand opportunities. Davidson KW, Alcántara C, Miller GE The American psychologist 30394780 Am Psychol 2018 Nov
COVID-19 in kidney transplant recipients. Nair V, Jandovitz N, Hirsch JS, Nair G, Abate M, Bhaskaran M, Grodstein E, Berlinrut I, Hirschwerk D, Cohen SL, Davidson KW, Dominello AJ, Osorio GA, Richardson S, Teperman LW, Molmenti EP American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 32351040 Am J Transplant 2020 Jul
In-Hospital 30-Day Survival Among Young Adults With Coronavirus Disease 2019: A Cohort Study. Richardson S, Gitlin J, Kozel Z, Levy S, Rahman H, Hirsch JS, McGinn T, Diefenbach MA Open forum infectious diseases 34183983 Open Forum Infect Dis 2021 Jun
Estimating the predictive value of negative severe acute respiratory coronavirus virus 2 (SARS-CoV-2) results: A prospective study. Hirschwerk D, Foley M, Lesser M, Farber B, Crawford JM, Davidson KW, Berry GJ, Smith E, Kast C, Volel V, McGinn T Infection control and hospital epidemiology 33298203 Infect Control Hosp Epidemiol 2021 Oct
Intersectional Identity and Racial Inequality During the COVID-19 Pandemic: Perspectives of Black Physician Mothers. Louisias M, Marrast L Journal of women's health (2002) 32762601 J Womens Health (Larchmt) 2020 Sep
Let Sleeping Patients Lie, avoiding unnecessary overnight vitals monitoring using a clinically based deep-learning model. Tóth V, Meytlis M, Barnaby DP, Bock KR, Oppenheim MI, Al-Abed Y, McGinn T, Davidson KW, Becker LB, Hirsch JS, Zanos TP NPJ digital medicine 33299116 NPJ Digit Med 2020 Nov 13
The Family of Single-Case Experimental Designs. Epstein LH, Dallery J Harvard data science review 36926648 Harv Data Sci Rev 2022
Experimental Designs to Optimize Treatments for Individuals: Personalized N-of-1 Trials. Davidson KW, Silverstein M, Cheung K, Paluch RA, Epstein LH JAMA pediatrics 33587109 JAMA Pediatr 2021 Apr 1
Association of race/ethnicity with mortality in patients hospitalized with COVID-19. Richardson S, Martinez J, Hirsch JS, Cerise J, Lesser M, Roswell RO, Davidson KW, Northwell Health COVID-19 Research Consortium PloS one 35925973 PLoS One 2022
Introducing Data Sciences to N-of-1 Designs, Statistics, Use-Cases, the Future, and the Moniker 'N-of-1' Trial. Davidson KW, Cheung YK, Friel CP, Suls J Harvard data science review 38009132 Harv Data Sci Rev 2022
Personalized Trial Ethics and Institutional Review Board Submissions. Samuel JP, Wootton SH Harvard data science review 38283318 Harv Data Sci Rev 2022
Expanding Knowledge and Changing Attitudes About Poverty: An Interactive, Interprofessional Approach. Marrast LM, Chim C, Tocco J, Coletti DJ, Nouryan C, Block L, Martinez J Journal of primary care & community health 35225052 J Prim Care Community Health 2022 Jan-Dec
Impact of Timing of Tocilizumab Use in Hospitalized Patients With SARS-CoV-2 Infection. Singh AK, Oks M, Husk G, Dechario SP, Mina B, Singh K, Kirschenbaum L, Carpati CM, Mahmoud O, Gabra NI, Ishikawa O, Altschultz E, Shah V, Mahajan A, Gautam A, Birnbaum B, Antonacci AC, Raoof S Respiratory care 34548407 Respir Care 2021 Dec
Significance of Multiple Adverse Social Determinants of Health on the Diagnosis, Control, and Management of Diabetes. Kim EJ, Abrahams S, Marrast L, Martinez J, Hanchate AD, Conigliaro J Journal of general internal medicine 32495092 J Gen Intern Med 2021 Jul
Machine learning to assist clinical decision-making during the COVID-19 pandemic. Debnath S, Barnaby DP, Coppa K, Makhnevich A, Kim EJ, Chatterjee S, Tóth V, Levy TJ, Paradis MD, Cohen SL, Hirsch JS, Zanos TP, Northwell COVID-19 Research Consortium Bioelectronic medicine 32665967 Bioelectron Med 2020
Early Experience of COVID-19 in a US Children's Hospital. Kainth MK, Goenka PK, Williamson KA, Fishbein JS, Subramony A, Barone S, Belfer JA, Feld LM, Krief WI, Palumbo N, Rajan S, Rocker J, Scotto T, Sharma S, Sokoloff WC, Schleien C, Rubin LG, NORTHWELL HEALTH COVID-19 RESEARCH CONSORTIUM Pediatrics 32680880 Pediatrics 2020 Oct
Characteristics, Cardiac Involvement, and Outcomes of Multisystem Inflammatory Syndrome of Childhood Associated with severe acute respiratory syndrome coronavirus 2 Infection. Capone CA, Subramony A, Sweberg T, Schneider J, Shah S, Rubin L, Schleien C, Northwell Health COVID-19 Research Consortium, Epstein S, Johnson JC, Kessel A, Misra N, Mitchell E, Palumbo N, Rajan S, Rocker J, Williamson K, Davidson KW The Journal of pediatrics 32553873 J Pediatr 2020 Sep
Patient preferences for personalized (N-of-1) trials: a conjoint analysis. Moise N, Wood D, Cheung YKK, Duan N, Onge TS, Duer-Hefele J, Pu T, Davidson KW, Kronish IM, Members of the “Personalized Trial Collaboratory” Journal of clinical epidemiology 29859242 J Clin Epidemiol 2018 Oct
Personalized (N-of-1) Trials for Depression: A Systematic Review. Kronish IM, Hampsey M, Falzon L, Konrad B, Davidson KW Journal of clinical psychopharmacology 29596148 J Clin Psychopharmacol 2018 Jun
N-of-1 Randomized Intervention Trials in Health Psychology: A Systematic Review and Methodology Critique. Shaffer JA, Kronish IM, Falzon L, Cheung YK, Davidson KW Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 30124759 Ann Behav Med 2018 Aug 16
Single case designs for early phase behavioral translational research in health psychology. Epstein LH, Bickel WK, Czajkowski SM, Paluch RA, Moeyaert M, Davidson KW Health psychology : official journal of the Division of Health Psychology, American Psychological Association 34370494 Health Psychol 2021 Dec
An early experience on the effect of solid organ transplant status on hospitalized COVID-19 patients. Nair V, Jandovitz N, Hirsch JS, Abate M, Satapathy SK, Roth N, Miyara SJ, Guevara S, Kressel AM, Xiang A, Wu G, Butensky SD, Lin D, Williams S, Bhaskaran MC, Majure DT, Grodstein E, Lau L, Nair G, Fahmy AE, Winnick A, Breslin N, Berlinrut I, Molmenti C, Becker LB, Malhotra P, Gautam-Goyal P, Lima B, Maybaum S, Shah SK, Takegawa R, Hayashida K, Shinozaki K, Teperman LW, Molmenti EP, Northwell Health COVID-19 Research Consortium American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 33443778 Am J Transplant 2021 Jul
BMI as a Risk Factor for Clinical Outcomes in Patients Hospitalized with COVID-19 in New York. Kim TS, Roslin M, Wang JJ, Kane J, Hirsch JS, Kim EJ, Northwell Health COVID-19 Research Consortium Obesity (Silver Spring, Md.) 33128848 Obesity (Silver Spring) 2021 Feb
Patients and primary care providers identify opportunities for personalized (N-of-1) trials in the mobile health era. Kronish IM, Alcántara C, Duer-Hefele J, St Onge T, Davidson KW, Carter EJ, Medina V, Cohn E, Moise N Journal of clinical epidemiology 28648833 J Clin Epidemiol 2017 Sep
Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, the Northwell COVID-19 Research Consortium, Barnaby DP, Becker LB, Chelico JD, Cohen SL, Cookingham J, Coppa K, Diefenbach MA, Dominello AJ, Duer-Hefele J, Falzon L, Gitlin J, Hajizadeh N, Harvin TG, Hirschwerk DA, Kim EJ, Kozel ZM, Marrast LM, Mogavero JN, Osorio GA, Qiu M, Zanos TP JAMA 32320003 JAMA 2020 May 26
Evaluating Personalized (N-of-1) Trials in Rare Diseases: How Much Experimentation Is Enough? Cheung K, Mitsumoto H Harvard data science review 38283317 Harv Data Sci Rev 2022
N-of-1 Trials, Their Reporting Guidelines, and the Advancement of Open Science Principles. Porcino A, Vohra S Harvard data science review 38031562 Harv Data Sci Rev 2022
A Series of Virtual Interventions for Chronic Lower Back Pain: A Feasibility Pilot Study for a Series of Personalized (N-of-1) Trials. Butler M, D'Angelo S, Kaplan M, Tashnim Z, Miller D, Ahn H, Falzon L, Dominello AJ, Foroughi C, Chandereng T, Cheung K, Davidson K Harvard data science review 37609556 Harv Data Sci Rev 2022
An R Shiny App for a Chronic Lower Back Pain Study, Personalized N-of-1 Trial. Chandereng T Harvard data science review 37091071 Harv Data Sci Rev 2022
Accommodating Serial Correlation and Sequential Design Elements in Personalized Studies and Aggregated Personalized Studies. Schork NJ Harvard data science review 37032736 Harv Data Sci Rev 2022
A Series of Personalized Virtual Light Therapy Interventions for Fatigue: Feasibility Randomized Crossover Trial for N-of-1 Treatment. Butler M, D'Angelo S, Ahn H, Chandereng T, Miller D, Perrin A, Romain AN, Scatoni A, Friel CP, Cheung YK, Davidson KW JMIR formative research 37721795 JMIR Form Res 2023 Sep 18
Sex-Based Differences in COVID-19 Outcomes. Tejpal A, Gianos E, Cerise J, Hirsch JS, Rosen S, Kohn N, Lesser M, Weinberg C, Majure D, Satapathy SK, Bernstein D, Barish MA, Spyropoulos AC, Brown RM Journal of women's health (2002) 33885345 J Womens Health (Larchmt) 2021 Apr
Barriers to the Use of Clinical Decision Support for the Evaluation of Pulmonary Embolism: Qualitative Interview Study. Richardson S, Dauber-Decker KL, McGinn T, Barnaby DP, Cattamanchi A, Pekmezaris R JMIR human factors 34346901 JMIR Hum Factors 2021 Aug 4
Usefulness of Elevated Troponin to Predict Death in Patients With COVID-19 and Myocardial Injury. Majure DT, Gruberg L, Saba SG, Kvasnovsky C, Hirsch JS, Jauhar R, Northwell Health COVID-19 Research Consortium The American journal of cardiology 33058800 Am J Cardiol 2021 Jan 1
Clinical Mortality in a Large COVID-19 Cohort: Observational Study. Jarrett M, Schultz S, Lyall J, Wang J, Stier L, De Geronimo M, Nelson K Journal of medical Internet research 32930099 J Med Internet Res 2020 Sep 25
Prevalence of SARS-CoV-2 Antibodies in Health Care Personnel in the New York City Area. Moscola J, Sembajwe G, Jarrett M, Farber B, Chang T, McGinn T, Davidson KW, Northwell Health COVID-19 Research Consortium JAMA 32780804 JAMA 2020 Sep 1
Racial and ethnic minority patient participation in N-of-1 trials: perspectives of healthcare providers and patients. Marrast L, Conigliaro J, Chan C, Kim EJ, Duer-Hefele J, Diefenbach MA, Davidson KW Personalized medicine 34047197 Per Med 2021 Jul
Risk factors and outcomes for acute-on-chronic liver failure in COVID-19: a large multi-center observational cohort study. Satapathy SK, Roth NC, Kvasnovsky C, Hirsch JS, Trindade AJ, Molmenti E, Barish M, Hirschwerk D, Da BL, Bernstein D, Northwell Health COVID-19 Research Consortium Hepatology international 33826042 Hepatol Int 2021 Jun
Barriers to and Facilitators for Acceptance of Comprehensive Clinical Decision Support System-Driven Care Maps for Patients With Thoracic Trauma: Interview Study Among Health Care Providers and Nurses. Jones EK, Banks A, Melton GB, Porta CM, Tignanelli CJ JMIR human factors 35293873 JMIR Hum Factors 2022 Mar 16
Conduct and Implementation of Personalized Trials in Research and Practice. Kravitz RL, Duan N Harvard data science review 38009129 Harv Data Sci Rev 2022
Personalized Data Science and Personalized (N-of-1) Trials: Promising Paradigms for Individualized Health Care. Duan N, Norman D, Schmid C, Sim I, Kravitz RL Harvard data science review 38009133 Harv Data Sci Rev 2022
The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection. Hazra T, Tapryal N, Chakraborty A, Rayavara K, Wakamiya M, Islam A, Pan L, Hsu J, Tat V, Maruyama J, Hosoki K, Sayed I, Alcantara J, Castillo V, Tindle C, Sarker A, Cardenas V, Sharma G, Alexander LC, Sur S, Ghosh G, Paessler S, Sahoo D, Ghosh P, Das S, Boldogh I, Tseng CT Research square 35665009 Res Sq 2022 May 27
Ultrafast Synthesis of Multifunctional Submicrometer Hollow Silica Spheres in Microfluidic Spiral Channels. Nie Y, Hao N, Zhang JXJ Scientific reports 28974729 Sci Rep 2017 Oct 3
Microfluidics-mediated self-template synthesis of anisotropic hollow ellipsoidal mesoporous silica nanomaterials. Hao N, Nie Y, Tadimety A, Closson AB, Zhang JXJ Materials research letters 30854261 Mater Res Lett 2017
Microfluidic continuous flow synthesis of functional hollow spherical silica with hierarchical sponge-like large porous shell. Hao N, Nie Y, Xu Z, Closson AB, Usherwood T, J Zhang JX Chemical engineering journal (Lausanne, Switzerland : 1996) 31762686 Chem Eng J 2019 Jun 15
Advances in liquid biopsy on-chip for cancer management: Technologies, biomarkers, and clinical analysis. Tadimety A, Closson A, Li C, Yi S, Shen T, Zhang JXJ Critical reviews in clinical laboratory sciences 29388456 Crit Rev Clin Lab Sci 2018 May
Biomimetic hierarchical walnut kernel-like and erythrocyte-like mesoporous silica nanomaterials: controllable synthesis and versatile applications. Hao N, Nie Y, Zhang JXJ Microporous and mesoporous materials : the official journal of the International Zeolite Association 29479288 Microporous Mesoporous Mater 2018 May 1
Microfluidics-enabled rational design of immunomagnetic nanomaterials and their shape effect on liquid biopsy. Hao N, Nie Y, Shen T, Zhang JXJ Lab on a chip 29923569 Lab Chip 2018 Jul 10
Combined immunomagnetic capture coupled with ultrasensitive plasmonic detection of circulating tumor cells in blood. Shen W, Song Y, Burklund A, Le B, Zhang R, Wang L, Xi Y, Qian K, Shen T, Zhang JXJ Biomedical microdevices 30417219 Biomed Microdevices 2018 Nov 12
Microfluidics for silica biomaterials synthesis: opportunities and challenges. Hao N , Nie Y , Zhang JXJ Biomaterials science 30919847 Biomater Sci 2019 May 28
Microfluidics-Based Organism Isolation from Whole Blood: An Emerging Tool for Bloodstream Infection Diagnosis. Burklund A, Zhang JXJ Annals of biomedical engineering 30980291 Ann Biomed Eng 2019 Jul
Microfluidics for ZnO micro-/nanomaterials development: rational design, controllable synthesis, and on-chip bioapplications. Hao N, Zhang M, Zhang JXJ Biomaterials science 31965125 Biomater Sci 2020 Mar 31
Plasmonic nanosensors for point-of-care biomarker detection. Jin C, Wu Z, Molinski JH, Zhou J, Ren Y, Zhang JXJ Materials today. Bio 35514435 Mater Today Bio 2022 Mar
Silver nanoparticle on zinc oxide array for label-free detection of opioids through surface-enhanced raman spectroscopy. Zhang M, Jin C, Nie Y, Ren Y, Hao N, Xu Z, Dong L, Zhang JXJ RSC advances 35423637 RSC Adv 2021 Mar 16
Plasmonic Nanoparticle Conjugation for Nucleic Acid Biosensing. Tadimety A, Zhang Y, Molinski JH, Palinski TJ, Tsongalis GJ, Zhang JXJ Methods in molecular biology (Clifton, N.J.) 34837175 Methods Mol Biol 2022
Scalable Signature-Based Molecular Diagnostics Through On-chip Biomarker Profiling Coupled with Machine Learning. Molinski J, Tadimety A, Burklund A, Zhang JXJ Annals of biomedical engineering 32816167 Ann Biomed Eng 2020 Oct
Flexible Piezoelectric Nanogenerators Using Metal-doped ZnO-PVDF Films. Jin C, Hao N, Xu Z, Trase I, Nie Y, Dong L, Closson A, Chen Z, Zhang JXJ Sensors and actuators. A, Physical 33380776 Sens Actuators A Phys 2020 Apr 15
Method for Inkjet-printing PEDOT:PSS polymer electrode arrays on piezoelectric PVDF-TrFE fibers. Closson A, Richards H, Xu Z, Jin C, Dong L, Zhang JXJ IEEE sensors journal 34899077 IEEE Sens J 2021 Dec
Microfluidic synthesis and on-chip enrichment application of two-dimensional hollow sandwich-like mesoporous silica nanosheet with water ripple-like surface. Hao N, Nie Y, Closson AB, Zhang JXJ Journal of colloid and interface science 30576991 J Colloid Interface Sci 2019 Mar 15
Microfluidics-enabled rapid manufacturing of hierarchical silica-magnetic microflower toward enhanced circulating tumor cell screening. Hao N , Nie Y , Tadimety A , Shen T , Zhang JXJ Biomaterials science 30375583 Biomater Sci 2018 Nov 20
Microfluidic enrichment of bacteria coupled to contact-free lysis on a magnetic polymer surface for downstream molecular detection. Burklund A, Petryk JD, Hoopes PJ, Zhang JXJ Biomicrofluidics 32642021 Biomicrofluidics 2020 May
Tunable Buckled Beams with Mesoporous PVDF-TrFE/SWCNT Composite Film for Energy Harvesting. Xu Z, Liu Y, Dong L, Closson AB, Hao N, Oglesby M, Escobar GP, Fu S, Han X, Wen C, Liu J, Feldman MD, Chen Z, Zhang JXJ ACS applied materials & interfaces 30199624 ACS Appl Mater Interfaces 2018 Oct 3
Vibration-Energy-Harvesting System: Transduction Mechanisms, Frequency Tuning Techniques, and Biomechanical Applications. Dong L, Closson AB, Jin C, Trase I, Chen Z, Zhang JXJ Advanced materials technologies 33829079 Adv Mater Technol 2019 Oct
Microfluidic In Situ Patterning of Silver Nanoparticles for Surface-Enhanced Raman Spectroscopic Sensing of Biomolecules. Nie Y, Jin C, Zhang JXJ ACS sensors 34148342 ACS Sens 2021 Jul 23
Patterned Plasmonic Surfaces-Theory, Fabrication, and Applications in Biosensing. Chorsi HT, Zhu Y, Zhang JXJ Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems 29276365 J Microelectromech Syst 2017 Aug
Multifunctional Pacemaker Lead for Cardiac Energy Harvesting and Pressure Sensing. Dong L, Closson AB, Jin C, Nie Y, Cabe A, Escobedo D, Huang S, Trase I, Xu Z, Chen Z, Feldman MD, Zhang JXJ Advanced healthcare materials 32347010 Adv Healthc Mater 2020 Jun
Implantable Cardiac Kirigami-Inspired Lead-Based Energy Harvester Fabricated by Enhanced Piezoelectric Composite Film. Xu Z, Jin C, Cabe A, Escobedo D, Gruslova A, Jenney S, Closson AB, Dong L, Chen Z, Feldman MD, Zhang JXJ Advanced healthcare materials 33434407 Adv Healthc Mater 2021 Apr
Ultrafast microfluidic synthesis of hierarchical triangular silver core-silica shell nanoplatelet toward enhanced cellular internalization. Hao N, Nie Y, Xu Z, Zhang JXJ Journal of colloid and interface science 30771632 J Colloid Interface Sci 2019 Apr 15
Flexible Electrostatic Transducer Array with Displacement Control for Haptic Sensing and Actuation. Trase I, Tan HZ, Chen Z, Zhang JXJ Sensors and actuators. A, Physical 33380777 Sens Actuators A Phys 2021 Jan 1
Microfluidics-enabled rational design of ZnO micro-/nanoparticles with enhanced photocatalysis, cytotoxicity, and piezoelectric properties. Hao N, Xu Z, Nie Y, Jin C, Closson AB, Zhang M, Zhang JXJ Chemical engineering journal (Lausanne, Switzerland : 1996) 32831625 Chem Eng J 2019 Dec 15
Edge effect of strained bilayer nanofilms for tunable multistability and actuation. Hu N, Han X, Huang S, Grover HM, Yu X, Zhang LN, Trase I, Zhang JX, Zhang L, Dong LX, Chen Z Nanoscale 28067396 Nanoscale 2017 Mar 2
Fibroblasts: Diverse Cells Critical to Biomaterials Integration. Hannan RT, Peirce SM, Barker TH ACS biomaterials science & engineering 31440581 ACS Biomater Sci Eng 2018 Apr 9
Detection of an Integrin-Binding Mechanoswitch within Fibronectin during Tissue Formation and Fibrosis. Cao L, Nicosia J, Larouche J, Zhang Y, Bachman H, Brown AC, Holmgren L, Barker TH ACS nano 28699736 ACS Nano 2017 Jul 25
Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasion. Stefanelli VL, Choudhury S, Hu P, Liu Y, Schwenzer A, Yeh CR, Chambers DM, von Beck K, Li W, Segura T, Midwood KS, Torres M, Barker TH Matrix biology : journal of the International Society for Matrix Biology 31004743 Matrix Biol 2019 Sep
The fibrotic tumor stroma. Yamauchi M, Barker TH, Gibbons DL, Kurie JM The Journal of clinical investigation 29293090 J Clin Invest 2018 Jan 2
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Macrophage and Fibroblast Interactions in Biomaterial-Mediated Fibrosis. Witherel CE, Abebayehu D, Barker TH, Spiller KL Advanced healthcare materials 30658015 Adv Healthc Mater 2019 Feb
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Increasing body mass index predicts increasing difficulty, failure rate, and time to discovery of failure of epidural anesthesia in laboring patients. Kula AO, Riess ML, Ellinas EH Journal of clinical anesthesia 28235511 J Clin Anesth 2017 Feb
Venous Waveform Analysis Correlates With Echocardiography in Detecting Hypovolemia in a Rat Hemorrhage Model. Lefevre RJ, Balzer C, Baudenbacher FJ, Riess ML, Hernandez A, Eagle SS Seminars in cardiothoracic and vascular anesthesia 32957831 Semin Cardiothorac Vasc Anesth 2021 Mar
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Poloxamer 188 Exerts Direct Protective Effects on Mouse Brain Microvascular Endothelial Cells in an In Vitro Traumatic Brain Injury Model. Lotze FP, Riess ML Biomedicines 34440247 Biomedicines 2021 Aug 19
A new method to predict return of spontaneous circulation by peripheral intravenous analysis during cardiopulmonary resuscitation: a rat model pilot study. Balzer C, Eagle SS, Baudenbacher FJ, Riess ML Intensive care medicine experimental 39531090 Intensive Care Med Exp 2024 Nov 12
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Outcomes of intermediate-risk patients treated with transcatheter and surgical aortic valve replacement in the Veterans Affairs Healthcare System: A single center 20-year experience. Garcia S, Kelly R, Mbai M, Gurevich S, Oestreich B, Yannopoulos D, Adabag S Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 29316204 Catheter Cardiovasc Interv 2018 Aug 1
Early Effects of Prolonged Cardiac Arrest and Ischemic Postconditioning during Cardiopulmonary Resuscitation on Cardiac and Brain Mitochondrial Function in Pigs. Matsuura TR, Bartos JA, Tsangaris A, Shekar KC, Olson MD, Riess ML, Bienengraeber M, Aufderheide TP, Neumar RW, Rees JN, McKnite SH, Dikalova AE, Dikalov SI, Douglas HF, Yannopoulos D Resuscitation 28408349 Resuscitation 2017 Jul
Early Access to the Cardiac Catheterization Laboratory for Patients Resuscitated From Cardiac Arrest Due to a Shockable Rhythm: The Minnesota Resuscitation Consortium Twin Cities Unified Protocol. Garcia S, Drexel T, Bekwelem W, Raveendran G, Caldwell E, Hodgson L, Wang Q, Adabag S, Mahoney B, Frascone R, Helmer G, Lick C, Conterato M, Baran K, Bart B, Bachour F, Roh S, Panetta C, Stark R, Haugland M, Mooney M, Wesley K, Yannopoulos D Journal of the American Heart Association 26744380 J Am Heart Assoc 2016 Jan 7
PPARγ-Independent Side Effects of Thiazolidinediones on Mitochondrial Redox State in Rat Isolated Hearts. Riess ML, Elorbany R, Weihrauch D, Stowe DF, Camara AKS Cells 31968546 Cells 2020 Jan 20
Minnesota Resuscitation Consortium's Advanced Perfusion and Reperfusion Cardiac Life Support Strategy for Out-of-Hospital Refractory Ventricular Fibrillation. Yannopoulos D, Bartos JA, Martin C, Raveendran G, Missov E, Conterato M, Frascone RJ, Trembley A, Sipprell K, John R, George S, Carlson K, Brunsvold ME, Garcia S, Aufderheide TP Journal of the American Heart Association 27412906 J Am Heart Assoc 2016 Jun 13
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Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest. Bartos JA, Matsuura TR, Sarraf M, Youngquist ST, McKnite SH, Rees JN, Sloper DT, Bates FS, Segal N, Debaty G, Lurie KG, Neumar RW, Metzger JM, Riess ML, Yannopoulos D Resuscitation 25447036 Resuscitation 2015 Feb
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Lipid emulsion enhances cardiac performance after ischemia-reperfusion in isolated hearts from summer-active arctic ground squirrels. Salzman MM, Cheng Q, Deklotz RJ, Dulai GK, Douglas HF, Dikalova AE, Weihrauch D, Barnes BM, Riess ML Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 28364393 J Comp Physiol B 2017 Jul
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Identifying Important Gaps in Randomized Controlled Trials of Adult Cardiac Arrest Treatments: A Systematic Review of the Published Literature. Sinha SS, Sukul D, Lazarus JJ, Polavarapu V, Chan PS, Neumar RW, Nallamothu BK Circulation. Cardiovascular quality and outcomes 27756794 Circ Cardiovasc Qual Outcomes 2016 Nov
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Total intravenous versus inhaled anesthesia in transsphenoidal tumor surgery. Gollapudy S, Poetker DM, Sidhu J, Riess ML American journal of otolaryngology 30017373 Am J Otolaryngol 2018 Sep-Oct
Reperfusion injury protection during Basic Life Support improves circulation and survival outcomes in a porcine model of prolonged cardiac arrest. Debaty G, Lurie K, Metzger A, Lick M, Bartos JA, Rees JN, McKnite S, Puertas L, Pepe P, Fowler R, Yannopoulos D Resuscitation 27211835 Resuscitation 2016 Aug
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Therapeutic Hypothermia in Children. Riess ML, Aufderheide TP, Yannopoulos D The New England journal of medicine 26332560 N Engl J Med 2015 Sep 3
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Sodium nitroprusside enhanced cardiopulmonary resuscitation improves short term survival in a porcine model of ischemic refractory ventricular fibrillation. Yannopoulos D, Bartos JA, George SA, Sideris G, Voicu S, Oestreich B, Matsuura T, Shekar K, Rees J, Aufderheide TP Resuscitation 27771299 Resuscitation 2017 Jan
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A Paper-Based Test for Screening Newborns for Sickle Cell Disease. Piety NZ, George A, Serrano S, Lanzi MR, Patel PR, Noli MP, Kahan S, Nirenberg D, Camanda JF, Airewele G, Shevkoplyas SS Scientific reports 28367971 Sci Rep 2017 Apr 3
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Trace incorporation of heavy water reveals slow and heterogeneous pathogen growth rates in cystic fibrosis sputum. Kopf SH, Sessions AL, Cowley ES, Reyes C, Van Sambeek L, Hu Y, Orphan VJ, Kato R, Newman DK Proceedings of the National Academy of Sciences of the United States of America 26715741 Proc Natl Acad Sci U S A 2016 Jan 12
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The dormancy-specific regulator, SutA, is intrinsically disordered and modulates transcription initiation in Pseudomonas aeruginosa. Bergkessel M, Babin BM, VanderVelde D, Sweredoski MJ, Moradian A, Eggleston-Rangel R, Hess S, Tirrell DA, Artsimovitch I, Newman DK Molecular microbiology 31254296 Mol Microbiol 2019 Sep
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Polyphosphate granule biogenesis is temporally and functionally tied to cell cycle exit during starvation in Pseudomonas aeruginosa. Racki LR, Tocheva EI, Dieterle MG, Sullivan MC, Jensen GJ, Newman DK Proceedings of the National Academy of Sciences of the United States of America 28265086 Proc Natl Acad Sci U S A 2017 Mar 21
Refining the Application of Microbial Lipids as Tracers of Staphylococcus aureus Growth Rates in Cystic Fibrosis Sputum. Neubauer C, Kasi AS, Grahl N, Sessions AL, Kopf SH, Kato R, Hogan DA, Newman DK Journal of bacteriology 30249710 J Bacteriol 2018 Dec 15
Identification of Fitness Determinants during Energy-Limited Growth Arrest in Pseudomonas aeruginosa. Basta DW, Bergkessel M, Newman DK mBio 29184024 mBio 2017 Nov 28
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The Pyruvate and α-Ketoglutarate Dehydrogenase Complexes of Pseudomonas aeruginosa Catalyze Pyocyanin and Phenazine-1-carboxylic Acid Reduction via the Subunit Dihydrolipoamide Dehydrogenase. Glasser NR, Wang BX, Hoy JA, Newman DK The Journal of biological chemistry 28174304 J Biol Chem 2017 Mar 31
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Spatial and planar profiling of Rac1/Cdc42 signaling in Alzheimer's disease brain. Akhtar SN, Tran TD, Chen YH, Lu Q Journal of Alzheimer's disease : JAD 39610278 J Alzheimers Dis 2024 Dec
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Therapeutic Effect of Y-27632 on Tumorigenesis and Cisplatin-Induced Peripheral Sensory Loss through RhoA-NF-κB. Zhu Y, Howard GA, Pittman K, Boykin C, Herring LE, Wilkerson EM, Verbanac K, Lu Q Molecular cancer research : MCR 31189689 Mol Cancer Res 2019 Sep
G-Protein Signaling in Alzheimer's Disease: Spatial Expression Validation of Semi-supervised Deep Learning-Based Computational Framework. Zhang DF, Penwell T, Chen YH, Koehler A, Wu R, Nik Akhtar S, Lu Q The Journal of neuroscience : the official journal of the Society for Neuroscience 39327003 J Neurosci 2024 Nov 6
Trans-Compartmental Regulation of Tight Junction Barrier Function. Naser AN, Lu Q, Chen YH Tissue barriers 36220768 Tissue Barriers 2023 Oct 2
RhoA-LIMK Signaling Axis Reveals Rostral-Caudal Plane and Spatial Dysregulation in the Brain of Alzheimer's Disease Mouse Models. Nik Akhtar S, Lu Q Journal of Alzheimer's disease : JAD 37718806 J Alzheimers Dis 2023
Nanoarchitecture and molecular interactions of epithelial cell junction proteins revealed by super-resolution microscopy. Naser AN, Guiler W, Lu Q, Chen YH Annals of the New York Academy of Sciences 35819053 Ann N Y Acad Sci 2022 Oct
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FZD2 Regulates Murine Hair Follicle Function and Maintenance. Brennan-Crispi DM, Frankfurter M, Murphy C, Sheng E, Xu M, Morrisey EE, Millar SE, Leung TH The Journal of investigative dermatology 35051380 J Invest Dermatol 2022 Aug
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, Owens AT, Margulies KB, Frank DB, Wu JC, Rader DJ, Yang W, Prosser BL, Musunuru K, Jain R Cell stem cell 33529599 Cell Stem Cell 2021 May 6
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AP-1 Mediates Cellular Adaptation and Memory Formation During Therapy Resistance. Li J, Ravindran PT, O'Farrell A, Busch GT, Boe RH, Niu Z, Woo S, Dunagin MC, Jain N, Goyal Y, Sarma K, Herlyn M, Raj A bioRxiv : the preprint server for biology 39091739 bioRxiv 2024 Jul 25
An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype. Shah PP, Keough KC, Gjoni K, Santini GT, Abdill RJ, Wickramasinghe NM, Dundes CE, Karnay A, Chen A, Salomon REA, Walsh PJ, Nguyen SC, Whalen S, Joyce EF, Loh KM, Dubois N, Pollard KS, Jain R Genome biology 36691074 Genome Biol 2023 Jan 23
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Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells. Goyal Y, Busch GT, Pillai M, Li J, Boe RH, Grody EI, Chelvanambi M, Dardani IP, Emert B, Bodkin N, Braun J, Fingerman D, Kaur A, Jain N, Ravindran PT, Mellis IA, Kiani K, Alicea GM, Fane ME, Ahmed SS, Li H, Chen Y, Chai C, Kaster J, Witt RG, Lazcano R, Ingram DR, Johnson SB, Wani K, Dunagin MC, Lazar AJ, Weeraratna AT, Wargo JA, Herlyn M, Raj A Nature 37468627 Nature 2023 Aug
Gene regulation gravitates toward either addition or multiplication when combining the effects of two signals. Sanford EM, Emert BL, Coté A, Raj A eLife 33284110 Elife 2020 Dec 7
Memory Sequencing Reveals Heritable Single-Cell Gene Expression Programs Associated with Distinct Cellular Behaviors. Shaffer SM, Emert BL, Reyes Hueros RA, Cote C, Harmange G, Schaff DL, Sizemore AE, Gupte R, Torre E, Singh A, Bassett DS, Raj A Cell 32735851 Cell 2020 Aug 20
Genetic screening for single-cell variability modulators driving therapy resistance. Torre EA, Arai E, Bayatpour S, Jiang CL, Beck LE, Emert BL, Shaffer SM, Mellis IA, Fane ME, Alicea GM, Budinich KA, Weeraratna AT, Shi J, Raj A Nature genetics 33398196 Nat Genet 2021 Jan
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Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity in vitro. Mellis IA, Edelstein HI, Truitt R, Goyal Y, Beck LE, Symmons O, Dunagin MC, Linares Saldana RA, Shah PP, Pérez-Bermejo JA, Padmanabhan A, Yang W, Jain R, Raj A Cell systems 34352221 Cell Syst 2021 Sep 22
Gene Networks with Transcriptional Bursting Recapitulate Rare Transient Coordinated High Expression States in Cancer. Schuh L, Saint-Antoine M, Sanford EM, Emert BL, Singh A, Marr C, Raj A, Goyal Y Cell systems 32325034 Cell Syst 2020 Apr 22
Systematically quantifying morphological features reveals constraints on organoid phenotypes. Beck LE, Lee J, Coté C, Dunagin MC, Lukonin I, Salla N, Chang MK, Hughes AJ, Mornin JD, Gartner ZJ, Liberali P, Raj A Cell systems 35705097 Cell Syst 2022 Jul 20
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Spatial transcriptomics reveals influence of microenvironment on intrinsic fates in melanoma therapy resistance. Boe RH, Triandafillou CG, Lazcano R, Wargo JA, Raj A bioRxiv : the preprint server for biology 39005406 bioRxiv 2024 Jul 2
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Picking Winners and Losers: Cell Competition in Tissue Development and Homeostasis. Kim W, Jain R Trends in genetics : TIG 32418713 Trends Genet 2020 Jul
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Allelic correlation is a marker of trade-offs between barriers to transmission of expression variability and signal responsiveness in genetic networks. Boe RH, Ayyappan V, Schuh L, Raj A Cell systems 36450286 Cell Syst 2022 Dec 21
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Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells. Jain N, Goyal Y, Dunagin MC, Cote CJ, Mellis IA, Emert B, Jiang CL, Dardani IP, Reffsin S, Arnett M, Yang W, Raj A Cell systems 38335955 Cell Syst 2024 Feb 21
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Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11. Dickson P, Simanski S, Ngundu JM, Kodadek T Cell chemical biology 32857986 Cell Chem Biol 2020 Nov 19
Synthesis and Screening of a DNA-Encoded Library of Non-Peptidic Macrocycles. Koesema E, Roy A, Paciaroni NG, Coito C, Tokmina-Roszyk M, Kodadek T Angewandte Chemie (International ed. in English) 35192245 Angew Chem Int Ed Engl 2022 Apr 25
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Structural characterization of a peptoid-inspired conformationally constrained oligomer (PICCO) bound to streptavidin. McEnaney P , Balzarini M , Park H , Kodadek T Chemical communications (Cambridge, England) 32785302 Chem Commun (Camb) 2020 Sep 16
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Hachimoji DNA and RNA: A genetic system with eight building blocks. Hoshika S, Leal NA, Kim MJ, Kim MS, Karalkar NB, Kim HJ, Bates AM, Watkins NE Jr, SantaLucia HA, Meyer AJ, DasGupta S, Piccirilli JA, Ellington AD, SantaLucia J Jr, Georgiadis MM, Benner SA Science (New York, N.Y.) 30792304 Science 2019 Feb 22
Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide. Singh I, Laos R, Hoshika S, Benner SA, Georgiadis MM Nucleic acids research 29986111 Nucleic Acids Res 2018 Sep 6
Ligand-Guided Selection with Artificially Expanded Genetic Information Systems against TCR-CD3ε. Zumrut H, Yang Z, Williams N, Arizala J, Batool S, Benner SA, Mallikaratchy P Biochemistry 31880917 Biochemistry 2020 Feb 4
An Aptamer-Nanotrain Assembled from Six-Letter DNA Delivers Doxorubicin Selectively to Liver Cancer Cells. Zhang L, Wang S, Yang Z, Hoshika S, Xie S, Li J, Chen X, Wan S, Li L, Benner SA, Tan W Angewandte Chemie (International ed. in English) 31650689 Angew Chem Int Ed Engl 2020 Jan 7
Electrochemical Reduction and Oxidation of Eight Unnatural 2'-Deoxynucleosides at a Pyrolytic Graphite Electrode. Špaček J, Karalkar N, Fojta M, Wang J, Benner SA Electrochimica acta 33087943 Electrochim Acta 2020 Dec 1
Building better polymerases: Engineering the replication of expanded genetic alphabets. Ouaray Z, Benner SA, Georgiadis MM, Richards NGJ The Journal of biological chemistry 33004440 J Biol Chem 2020 Dec 11
Enzymatic synthesis and nanopore sequencing of 12-letter supernumerary DNA. Kawabe H, Thomas CA, Hoshika S, Kim MJ, Kim MS, Miessner L, Kaplan N, Craig JM, Gundlach JH, Laszlo AH, Benner SA, Marchand JA Nature communications 37884513 Nat Commun 2023 Oct 26
Assessing Readability of an 8-Letter Expanded Deoxyribonucleic Acid Alphabet with Nanopores. Thomas CA, Craig JM, Hoshika S, Brinkerhoff H, Huang JR, Abell SJ, Kim HC, Franzi MC, Carrasco JD, Kim HJ, Smith DC, Gundlach JH, Benner SA, Laszlo AH Journal of the American Chemical Society 37036666 J Am Chem Soc 2023 Apr 10
The peculiar genetics of the ribosomal DNA blurs the boundaries of transgenerational epigenetic inheritance. Bughio F, Maggert KA Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 30511202 Chromosome Res 2019 Mar
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The processivity factor Pol32 mediates nuclear localization of DNA polymerase delta and prevents chromosomal fragile site formation in Drosophila development. Ji J, Tang X, Hu W, Maggert KA, Rong YS PLoS genetics 31100062 PLoS Genet 2019 May
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Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane. Nichols AL, Blumenfeld Z, Luebbert L, Knox HJ, Muthusamy AK, Marvin JS, Kim CH, Grant SN, Walton DP, Cohen BN, Hammar R, Looger L, Artursson P, Dougherty DA, Lester HA The Journal of neuroscience : the official journal of the Society for Neuroscience 36868853 J Neurosci 2023 Mar 29
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids. Haloi N, Huang S, Nichols AL, Fine EJ, Friesenhahn NJ, Marotta CB, Dougherty DA, Lindahl E, Howard RJ, Mayo SL, Lester HA Protein engineering, design & selection : PEDS 38302088 Protein Eng Des Sel 2024 Jan 29
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Proteins for increased surface expression of the α6β4 nicotinic acetylcholine receptor: nothing but good news? Grant S, Lester HA The Journal of clinical investigation 33074245 J Clin Invest 2020 Nov 2
Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids. Haloi N, Huang S, Nichols AL, Fine EJ, Friesenhahn NJ, Marotta CB, Dougherty DA, Lindahl E, Howard RJ, Mayo SL, Lester HA bioRxiv : the preprint server for biology 36712031 bioRxiv 2024 Jan 18
Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids. Muthusamy AK, Kim CH, Virgil SC, Knox HJ, Marvin JS, Nichols AL, Cohen BN, Dougherty DA, Looger LL, Lester HA Journal of the American Chemical Society 35446570 J Am Chem Soc 2022 May 18
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Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum. Bera K, Kamajaya A, Shivange AV, Muthusamy AK, Nichols AL, Borden PM, Grant S, Jeon J, Lin E, Bishara I, Chin TM, Cohen BN, Kim CH, Unger EK, Tian L, Marvin JS, Looger LL, Lester HA Frontiers in cellular neuroscience 31798415 Front Cell Neurosci 2019
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Overcoming fixation and permeabilization challenges in flow cytometry by optical barcoding and multi-pass acquisition. Fahlberg MD, Forward S, Assita ER, Mazzola M, Kiem A, Handley M, Yun SH, Kwok SJJ bioRxiv : the preprint server for biology 39185194 bioRxiv 2024 Aug 16
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Polymeric nanofiber coating with tunable combinatorial antibiotic delivery prevents biofilm-associated infection in vivo. Ashbaugh AG, Jiang X, Zheng J, Tsai AS, Kim WS, Thompson JM, Miller RJ, Shahbazian JH, Wang Y, Dillen CA, Ordonez AA, Chang YS, Jain SK, Jones LC, Sterling RS, Mao HQ, Miller LS Proceedings of the National Academy of Sciences of the United States of America 27791154 Proc Natl Acad Sci U S A 2016 Nov 8
Efficient ribcage segmentation from CT scans using shape features. Xu Z, Bagci U, Jonsson C, Jain S, Mollura DJ Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 25570597 Annu Int Conf IEEE Eng Med Biol Soc 2014
Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions. Ordonez AA, Wang H, Magombedze G, Ruiz-Bedoya CA, Srivastava S, Chen A, Tucker EW, Urbanowski ME, Pieterse L, Fabian Cardozo E, Lodge MA, Shah MR, Holt DP, Mathews WB, Dannals RF, Gobburu JVS, Peloquin CA, Rowe SP, Gumbo T, Ivaturi VD, Jain SK Nature medicine 32066976 Nat Med 2020 Apr
Molecular Imaging: a Novel Tool To Visualize Pathogenesis of Infections In Situ. Gordon O, Ruiz-Bedoya CA, Ordonez AA, Tucker EW, Jain SK mBio 31662452 mBio 2019 Oct 29
Advanced imaging tools for childhood tuberculosis: potential applications and research needs. Jain SK, Andronikou S, Goussard P, Antani S, Gomez-Pastrana D, Delacourt C, Starke JR, Ordonez AA, Jean-Philippe P, Browning RS, Perez-Velez CM The Lancet. Infectious diseases 32589869 Lancet Infect Dis 2020 Nov
Balancing the Risks of Radiation and Anesthesia in Pediatric Patients. Tucker EW, Jain SK, Mahesh M Journal of the American College of Radiology : JACR 28750847 J Am Coll Radiol 2017 Nov
Imaging Enterobacterales infections in patients using pathogen-specific positron emission tomography. Ordonez AA, Wintaco LM, Mota F, Restrepo AF, Ruiz-Bedoya CA, Reyes CF, Uribe LG, Abhishek S, D'Alessio FR, Holt DP, Dannals RF, Rowe SP, Castillo VR, Pomper MG, Granados U, Jain SK Science translational medicine 33853931 Sci Transl Med 2021 Apr 14
Dynamic PET-facilitated modeling and high-dose rifampin regimens for Staphylococcus aureus orthopedic implant-associated infections. Gordon O, Lee DE, Liu B, Langevin B, Ordonez AA, Dikeman DA, Shafiq B, Thompson JM, Sponseller PD, Flavahan K, Lodge MA, Rowe SP, Dannals RF, Ruiz-Bedoya CA, Read TD, Peloquin CA, Archer NK, Miller LS, Davis KM, Gobburu JVS, Jain SK Science translational medicine 34851697 Sci Transl Med 2021 Dec
Positron Emission Tomography Imaging with 2-[(18)F]F- p-Aminobenzoic Acid Detects Staphylococcus aureus Infections and Monitors Drug Response. Zhang Z, Ordonez AA, Wang H, Li Y, Gogarty KR, Weinstein EA, Daryaee F, Merino J, Yoon GE, Kalinda AS, Mease RC, Iuliano JN, Smith-Jones PM, Jain SK, Tonge PJ ACS infectious diseases 30067329 ACS Infect Dis 2018 Nov 9
Imaging Macrophage-associated Inflammation. Foss CA, Sanchez-Bautista J, Jain SK Seminars in nuclear medicine 29626941 Semin Nucl Med 2018 May
[(11)C]Para-Aminobenzoic Acid: A Positron Emission Tomography Tracer Targeting Bacteria-Specific Metabolism. Mutch CA, Ordonez AA, Qin H, Parker M, Bambarger LE, Villanueva-Meyer JE, Blecha J, Carroll V, Taglang C, Flavell R, Sriram R, VanBrocklin H, Rosenberg O, Ohliger MA, Jain SK, Neumann KD, Wilson DM ACS infectious diseases 29712422 ACS Infect Dis 2018 Jul 13
Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data. Rifat D, Prideaux B, Savic RM, Urbanowski ME, Parsons TL, Luna B, Marzinke MA, Ordonez AA, DeMarco VP, Jain SK, Dartois V, Bishai WR, Dooley KE Science translational medicine 29618565 Sci Transl Med 2018 Apr 4
Kit-based synthesis of 2-deoxy-2-[(18)F]-fluoro-D-sorbitol for bacterial imaging. Mota F, De Jesus P, Jain SK Nature protocols 34686858 Nat Protoc 2021 Nov
Matrix Metalloproteinases in Pulmonary and Central Nervous System Tuberculosis-A Review. Rohlwink UK, Walker NF, Ordonez AA, Li YJ, Tucker EW, Elkington PT, Wilkinson RJ, Wilkinson KA International journal of molecular sciences 30889803 Int J Mol Sci 2019 Mar 18
The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas. Bhattacharya B, Xiao S, Chatterjee S, Urbanowski M, Ordonez A, Ihms EA, Agrahari G, Lun S, Berland R, Pichugin A, Gao Y, Connor J, Ivanov AR, Yan BS, Kobzik L, Koo BB, Jain S, Bishai W, Kramnik I The Journal of clinical investigation 33301427 J Clin Invest 2021 Feb 1
The biodistribution of 5-[18F]fluoropyrazinamide in Mycobacterium tuberculosis-infected mice determined by positron emission tomography. Zhang Z, Ordonez AA, Smith-Jones P, Wang H, Gogarty KR, Daryaee F, Bambarger LE, Chang YS, Jain SK, Tonge PJ PloS one 28151985 PLoS One 2017
The Promise of Molecular Imaging in the Study and Treatment of Infectious Diseases. Jain SK Molecular imaging and biology 28155078 Mol Imaging Biol 2017 Jun
Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis. Lentz CS, Ordonez AA, Kasperkiewicz P, La Greca F, O'Donoghue AJ, Schulze CJ, Powers JC, Craik CS, Drag M, Jain SK, Bogyo M ACS infectious diseases 27739665 ACS Infect Dis 2016 Nov 11
Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology. Ordonez AA, Pokkali S, Sanchez-Bautista J, Klunk MH, Urbanowski ME, Kübler A, Bishai WR, Elkington PT, Jain SK The Journal of infectious diseases 29920600 J Infect Dis 2019 Jan 29
Imaging Chronic Tuberculous Lesions Using Sodium [(18)F]Fluoride Positron Emission Tomography in Mice. Ordonez AA, DeMarco VP, Klunk MH, Pokkali S, Jain SK Molecular imaging and biology 25750032 Mol Imaging Biol 2015 Oct
Extensively drug-resistant tuberculosis in a young child after travel to India. Salazar-Austin N, Ordonez AA, Hsu AJ, Benson JE, Mahesh M, Menachery E, Razeq JH, Salfinger M, Starke JR, Milstone AM, Parrish N, Nuermberger EL, Jain SK The Lancet. Infectious diseases 26607130 Lancet Infect Dis 2015 Dec
Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9. Ordonez AA, Tasneen R, Pokkali S, Xu Z, Converse PJ, Klunk MH, Mollura DJ, Nuermberger EL, Jain SK Disease models & mechanisms 27482816 Dis Model Mech 2016 Jul 1
Radiosynthesis and PET Bioimaging of (76)Br-Bedaquiline in a Murine Model of Tuberculosis. Ordonez AA, Carroll LS, Abhishek S, Mota F, Ruiz-Bedoya CA, Klunk MH, Singh AK, Freundlich JS, Mease RC, Jain SK ACS infectious diseases 31345032 ACS Infect Dis 2019 Dec 13
Delamanid Central Nervous System Pharmacokinetics in Tuberculous Meningitis in Rabbits and Humans. Tucker EW, Pieterse L, Zimmerman MD, Udwadia ZF, Peloquin CA, Gler MT, Ganatra S, Tornheim JA, Chawla P, Caoili JC, Ritchie B, Jain SK, Dartois V, Dooley KE Antimicrobial agents and chemotherapy 31383662 Antimicrob Agents Chemother 2019 Oct
Radiosynthesis and validation of [Carboxy-(11) C]4-Aminobenzoic acid ([(11) C]PABA), a PET radiotracer for imaging bacterial infections. Holt DP, Kalinda AS, Bambarger LE, Jain SK, Dannals RF Journal of labelled compounds & radiopharmaceuticals 30089334 J Labelled Comp Radiopharm 2019 Jan
Radiotracer Development for Bacterial Imaging. Mota F, Ordonez AA, Firth G, Ruiz-Bedoya CA, Ma MT, Jain SK Journal of medicinal chemistry 32048838 J Med Chem 2020 Mar 12
In vivo prediction of tuberculosis-associated cavity formation in rabbits. Luna B, Kubler A, Larsson C, Foster B, Bagci U, Mollura DJ, Jain SK, Bishai WR The Journal of infectious diseases 25117755 J Infect Dis 2015 Feb 1
Flagging Bacteria with Radiolabeled d-Amino Acids. Mota F, Jain SK ACS central science 32123728 ACS Cent Sci 2020 Feb 26
Stability and Viability of SARS-CoV-2. Rubens JH, Karakousis PC, Jain SK The New England journal of medicine 32283575 N Engl J Med 2020 May 14
(11)C-PABA as a PET Radiotracer for Functional Renal Imaging: Preclinical and First-in-Human Study. Ruiz-Bedoya CA, Ordonez AA, Werner RA, Plyku D, Klunk MH, Leal J, Lesniak WG, Holt DP, Dannals RF, Higuchi T, Rowe SP, Jain SK Journal of nuclear medicine : official publication, Society of Nuclear Medicine 32198314 J Nucl Med 2020 Nov
Novel vaccine strategies against tuberculosis: a road less travelled. Pokkali S, Jain S Expert review of vaccines 24195477 Expert Rev Vaccines 2013 Dec
Tuberculous meningitis: a roadmap for advancing basic and translational research. Jain SK, Tobin DM, Tucker EW, Venketaraman V, Ordonez AA, Jayashankar L, Siddiqi OK, Hammoud DA, Prasadarao NV, Sandor M, Hafner R, Fabry Z, NIH Tuberculous Meningitis Writing Group Nature immunology 29777209 Nat Immunol 2018 Jun
A Systematic Approach for Developing Bacteria-Specific Imaging Tracers. Ordonez AA, Weinstein EA, Bambarger LE, Saini V, Chang YS, DeMarco VP, Klunk MH, Urbanowski ME, Moulton KL, Murawski AM, Pokkali S, Kalinda AS, Jain SK Journal of nuclear medicine : official publication, Society of Nuclear Medicine 27635025 J Nucl Med 2017 Jan
Determination of [11C]rifampin pharmacokinetics within Mycobacterium tuberculosis-infected mice by using dynamic positron emission tomography bioimaging. DeMarco VP, Ordonez AA, Klunk M, Prideaux B, Wang H, Zhuo Z, Tonge PJ, Dannals RF, Holt DP, Lee CK, Weinstein EA, Dartois V, Dooley KE, Jain SK Antimicrobial agents and chemotherapy 26169396 Antimicrob Agents Chemother 2015 Sep
Joint solution for PET image segmentation, denoising, and partial volume correction. Xu Z, Gao M, Papadakis GZ, Luna B, Jain S, Mollura DJ, Bagci U Medical image analysis 29627687 Med Image Anal 2018 May
Capsules for biomedical image segmentation. LaLonde R, Xu Z, Irmakci I, Jain S, Bagci U Medical image analysis 33246227 Med Image Anal 2021 Feb
Cavitary tuberculosis: the gateway of disease transmission. Urbanowski ME, Ordonez AA, Ruiz-Bedoya CA, Jain SK, Bishai WR The Lancet. Infectious diseases 32482293 Lancet Infect Dis 2020 Jun
Imaging Pulmonary Foreign Body Reaction Using [(125)I]iodo-DPA-713 SPECT/CT in Mice. Sanchez-Bautista J, Foss CA, Ordonez AA, Klunk MH, Jain SK Molecular imaging and biology 29987615 Mol Imaging Biol 2019 Apr
Caspase-Based PET for Evaluating Pro-Apoptotic Treatments in a Tuberculosis Mouse Model. Ordonez AA, Abhishek S, Singh AK, Klunk MH, Azad BB, Aboagye EO, Carroll L, Jain SK Molecular imaging and biology 32232626 Mol Imaging Biol 2020 Dec
Computer-aided pulmonary image analysis in small animal models. Xu Z, Bagci U, Mansoor A, Kramer-Marek G, Luna B, Kubler A, Dey B, Foster B, Papadakis GZ, Camp JV, Jonsson CB, Bishai WR, Jain S, Udupa JK, Mollura DJ Medical physics 26133591 Med Phys 2015 Jul
Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation. Ordonez AA, Sellmyer MA, Gowrishankar G, Ruiz-Bedoya CA, Tucker EW, Palestro CJ, Hammoud DA, Jain SK Science translational medicine 31484790 Sci Transl Med 2019 Sep 4
Visualizing the dynamics of tuberculosis pathology using molecular imaging. Ordonez AA, Tucker EW, Anderson CJ, Carter CL, Ganatra S, Kaushal D, Kramnik I, Lin PL, Madigan CA, Mendez S, Rao J, Savic RM, Tobin DM, Walzl G, Wilkinson RJ, Lacourciere KA, Via LE, Jain SK The Journal of clinical investigation 33645551 J Clin Invest 2021 Mar 1
Microglia activation in a pediatric rabbit model of tuberculous meningitis. Tucker EW, Pokkali S, Zhang Z, DeMarco VP, Klunk M, Smith ES, Ordonez AA, Penet MF, Bhujwalla Z, Jain SK, Kannan S Disease models & mechanisms 27935825 Dis Model Mech 2016 Dec 1
Noninvasive (11)C-rifampin positron emission tomography reveals drug biodistribution in tuberculous meningitis. Tucker EW, Guglieri-Lopez B, Ordonez AA, Ritchie B, Klunk MH, Sharma R, Chang YS, Sanchez-Bautista J, Frey S, Lodge MA, Rowe SP, Holt DP, Gobburu JVS, Peloquin CA, Mathews WB, Dannals RF, Pardo CA, Kannan S, Ivaturi VD, Jain SK Science translational medicine 30518610 Sci Transl Med 2018 Dec 5
Pathogen-Specific Bacterial Imaging in Nuclear Medicine. Ordonez AA, Jain SK Seminars in nuclear medicine 29452620 Semin Nucl Med 2018 Mar
SPECT/CT Imaging of Mycobacterium tuberculosis Infection with [(125)I]anti-C3d mAb. Foss CA, Kulik L, Ordonez AA, Jain SK, Michael Holers V, Thurman JM, Pomper MG Molecular imaging and biology 29998399 Mol Imaging Biol 2019 Jun
Re: Increased 18F-2-Fluorodeoxysorbitol (18F-FDS) Activity in a Pituitary Spindle Cell Carcinoma. Javadi MS, Ordonez AA, Jain SK Clinical nuclear medicine 28319504 Clin Nucl Med 2017 Aug
Successful cure of extensively drug-resistant pulmonary tuberculosis in a young child. Salazar-Austin N, Akinboyo I, Jain SK The Lancet. Infectious diseases 28845790 Lancet Infect Dis 2017 Sep
High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis. Ruiz-Bedoya CA, Mota F, Tucker EW, Mahmud FJ, Reyes-Mantilla MI, Erice C, Bahr M, Flavahan K, de Jesus P, Kim J, Foss CA, Peloquin CA, Hammoud DA, Ordonez AA, Pardo CA, Jain SK The Journal of clinical investigation 35085105 J Clin Invest 2022 Mar 15
11C-Para-aminobenzoic acid PET imaging of S. aureus and MRSA infection in preclinical models and humans. Ordonez AA, Parker MF, Miller RJ, Plyku D, Ruiz-Bedoya CA, Tucker EW, Luu JM, Dikeman DA, Lesniak WG, Holt DP, Dannals RF, Miller LS, Rowe SP, Wilson DM, Jain SK JCI insight 35014627 JCI Insight 2022 Jan 11
Rabbit model of Staphylococcus aureus implant-associated spinal infection. Gordon O, Miller RJ, Thompson JM, Ordonez AA, Klunk MH, Dikeman DA, Joyce DP, Ruiz-Bedoya CA, Miller LS, Jain SK Disease models & mechanisms 32586832 Dis Model Mech 2020 Jul 28
Radiosynthesis and Biodistribution of (18)F-Linezolid in Mycobacterium tuberculosis-Infected Mice Using Positron Emission Tomography. Mota F, Jadhav R, Ruiz-Bedoya CA, Ordonez AA, Klunk MH, Freundlich JS, Jain SK ACS infectious diseases 32243132 ACS Infect Dis 2020 May 8
Molecular Imaging of Diabetic Foot Infections: New Tools for Old Questions. Ruiz-Bedoya CA, Gordon O, Mota F, Abhishek S, Tucker EW, Ordonez AA, Jain SK International journal of molecular sciences 31795077 Int J Mol Sci 2019 Nov 28
PET/CT imaging of CSF1R in a mouse model of tuberculosis. Foss CA, Ordonez AA, Naik R, Das D, Hall A, Wu Y, Dannals RF, Jain SK, Pomper MG, Horti AG European journal of nuclear medicine and molecular imaging 35713665 Eur J Nucl Med Mol Imaging 2022 Oct
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Hippo Signaling Pathway Activation during SARS-CoV-2 Infection Contributes to Host Antiviral Response. Garcia G Jr, Wang Y, Ignatius Irudayam J, Jeyachandran AV, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts B, Deb A, Ramaiah A, Arumugaswami V bioRxiv : the preprint server for biology 35441167 bioRxiv 2022 Apr 8
Replication-Deficient Zika Vector-Based Vaccine Provides Maternal and Fetal Protection in Mouse Model. Garcia G Jr, Chakravarty N, Abu AE, Jeyachandran AV, Takano KA, Brown R, Morizono K, Arumugaswami V Microbiology spectrum 36169338 Microbiol Spectr 2022 Oct 26
Development of a blocker of the universal phosphatidylserine- and phosphatidylethanolamine-dependent viral entry pathways. Song DH, Garcia G Jr, Situ K, Chua BA, Hong MLO, Do EA, Ramirez CM, Harui A, Arumugaswami V, Morizono K Virology 34020328 Virology 2021 Aug
Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response. Garcia G Jr, Jeyachandran AV, Wang Y, Irudayam JI, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts BN, Deb A, Ramaiah A, Arumugaswami V PLoS biology 36346780 PLoS Biol 2022 Nov
Differential Susceptibility of Ex Vivo Primary Glioblastoma Tumors to Oncolytic Effect of Modified Zika Virus. Garcia G Jr, Chakravarty N, Paiola S, Urena E, Gyani P, Tse C, French SW, Danielpour M, Breunig JJ, Nathanson DA, Arumugaswami V Cells 37830597 Cells 2023 Sep 29
Fibroblasts in heart scar tissue directly regulate cardiac excitability and arrhythmogenesis. Wang Y, Li Q, Tao B, Angelini M, Ramadoss S, Sun B, Wang P, Krokhaleva Y, Ma F, Gu Y, Espinoza A, Yamauchi K, Pellegrini M, Novitch B, Olcese R, Qu Z, Song Z, Deb A Science (New York, N.Y.) 37769108 Science 2023 Sep 29
Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses. Jeyachandran AV, Irudayam JI, Dubey S, Chakravarty N, Konda B, Shah A, Su B, Wang C, Cui Q, Williams KJ, Srikanth S, Shi Y, Deb A, Damoiseaux R, Stripp BR, Ramaiah A, Arumugaswami V bioRxiv : the preprint server for biology 37577539 bioRxiv 2023 Aug 5
Differential Susceptibility of Fetal Retinal Pigment Epithelial Cells, hiPSC- Retinal Stem Cells, and Retinal Organoids to Zika Virus Infection. Contreras D, Garcia G Jr, Jones MK, Martinez LE, Jayakarunakaran A, Gangalapudi V, Tang J, Wu Y, Zhao JJ, Chen Z, Ramaiah A, Tsui I, Kumar A, Nielsen-Saines K, Wang S, Arumugaswami V Viruses 36680182 Viruses 2023 Jan 1
Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses. Garcia G Jr, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Cario SC, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells M, Ramaiah A, Arumugaswami V bioRxiv : the preprint server for biology 36711787 bioRxiv 2023 Jan 20
Longitudinal Evaluation of Antibody Persistence in Mother-Infant Dyads After Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy. Cambou MC, Liu CM, Mok T, Fajardo-Martinez V, Paiola SG, Ibarrondo FJ, Kerin T, Fuller T, Tobin NH, Garcia G, Bhattacharya D, Aldrovandi GM, Arumugaswami V, Foo SS, Jung JU, Vasconcelos Z, Brasil P, Brendolin M, Yang OO, Rao R, Nielsen-Saines K The Journal of infectious diseases 36082433 J Infect Dis 2023 Jan 11
SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response. Singh S, Garcia G Jr, Shah R, Kramerov AA, Wright RE 3rd, Spektor TM, Ljubimov AV, Arumugaswami V, Kumar A The ocular surface 34583089 Ocul Surf 2022 Jan
A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation. Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A Communications biology 37923961 Commun Biol 2023 Nov 3
Neurological pathophysiology of SARS-CoV-2 and pandemic potential RNA viruses: a comparative analysis. Chakravarty N, Senthilnathan T, Paiola S, Gyani P, Castillo Cario S, Urena E, Jeysankar A, Jeysankar P, Ignatius Irudayam J, Natesan Subramanian S, Lavretsky H, Joshi S, Garcia G Jr, Ramaiah A, Arumugaswami V FEBS letters 34757622 FEBS Lett 2021 Dec
Mpox Virus and its ocular surface manifestations. Chakravarty N, Hemani D, Paravastu R, Ahmad Z, Palani SN, Arumugaswami V, Kumar A The ocular surface 38972544 Ocul Surf 2024 Oct
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair. Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, Braddock DT, MacRae VE, Banerjee U, Chiou PY, Seldin M, Huang D, Teitell M, Gertsman I, Jung M, Bensinger SJ, Damoiseaux R, Faull K, Pellegrini M, Lusis AJ, Graeber TG, Radu CG, Deb A The Journal of clinical investigation 34813507 J Clin Invest 2022 Jan 18
Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition. Liu X, Verma A, Garcia G Jr, Ramage H, Lucas A, Myers RL, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS Proceedings of the National Academy of Sciences of the United States of America 34593624 Proc Natl Acad Sci U S A 2021 Oct 19
ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling. Wu B, Ramaiah A, Garcia G Jr, Hasiakos S, Arumugaswami V, Srikanth S Journal of immunology (Baltimore, Md. : 1950) 34819389 J Immunol 2022 Jan 1
The Apolipoprotein E neutralizing antibody inhibits SARS-CoV-2 infection by blocking cellular entry of lipoviral particles. Cui Q, Jeyachandran AV, Garcia G, Qin C, Zhou Y, Zhang M, Wang C, Sun G, Liu W, Zhou T, Feng L, Palmer C, Li Z, Aziz A, Gomperts BN, Feng P, Arumugaswami V, Shi Y MedComm 37822714 MedComm (2020) 2023 Oct
In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics. Chauhan D, Chakravarty N, Jeyachandran AV, Jayakarunakaran A, Sinha S, Mishra R, Arumugaswami V, Ramaiah A Viruses 36366559 Viruses 2022 Nov 6
Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses. Garcia G Jr, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Castillo Cario S, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells MS, Ramaiah A, Arumugaswami V Cell reports. Medicine 37119814 Cell Rep Med 2023 May 16
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS Nature communications 37185252 Nat Commun 2023 Apr 25
Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery. Qin W, Myers SA, Carey DK, Carr SA, Ting AY Nature communications 34404792 Nat Commun 2021 Aug 17
Dynamic mapping of proteome trafficking within and between living cells by TransitID. Qin W, Cheah JS, Xu C, Messing J, Freibaum BD, Boeynaems S, Taylor JP, Udeshi ND, Carr SA, Ting AY Cell 37385249 Cell 2023 Jul 20
Identifying Common Molecular Mechanisms in Experimental and Human Acute Kidney Injury. Gerhardt LMS, McMahon AP Seminars in nephrology 36402654 Semin Nephrol 2022 May
Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane. Cygan AM, Jean Beltran PM, Mendoza AG, Branon TC, Ting AY, Carr SA, Boothroyd JC mBio 34749525 mBio 2021 Dec 21
Proximity labeling in mammalian cells with TurboID and split-TurboID. Cho KF, Branon TC, Udeshi ND, Myers SA, Carr SA, Ting AY Nature protocols 33139955 Nat Protoc 2020 Dec
Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. Li J, Han S, Li H, Udeshi ND, Svinkina T, Mani DR, Xu C, Guajardo R, Xie Q, Li T, Luginbuhl DJ, Wu B, McLaughlin CN, Xie A, Kaewsapsak P, Quake SR, Carr SA, Ting AY, Luo L Cell 31955847 Cell 2020 Jan 23
Coordination of tumor growth and host wasting by tumor-derived Upd3. Ding G, Xiang X, Hu Y, Xiao G, Chen Y, Binari R, Comjean A, Li J, Rushworth E, Fu Z, Mohr SE, Perrimon N, Song W Cell reports 34407411 Cell Rep 2021 Aug 17
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Proximal tubule responses to injury: interrogation by single-cell transcriptomics. Cippà PE, McMahon AP Current opinion in nephrology and hypertension 37074682 Curr Opin Nephrol Hypertens 2023 Jul 1
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Proximity labeling reveals non-centrosomal microtubule-organizing center components required for microtubule growth and localization. Sanchez AD, Branon TC, Cote LE, Papagiannakis A, Liang X, Pickett MA, Shen K, Jacobs-Wagner C, Ting AY, Feldman JL Current biology : CB 34242576 Curr Biol 2021 Aug 23
Protein phosphatase 1 regulates core PCP signaling. Song S, Cho B, Weiner AT, Nissen SB, Ojeda Naharros I, Sanchez Bosch P, Suyama K, Hu Y, He L, Svinkina T, Udeshi ND, Carr SA, Perrimon N, Axelrod JD EMBO reports 37975164 EMBO Rep 2023 Dec 6
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Repairing the blood-brain barrier. McMahon AP, Ichida JK Science (New York, N.Y.) 35175806 Science 2022 Feb 18
A genetic model for in vivo proximity labelling of the mammalian secretome. Yang R, Meyer AS, Droujinine IA, Udeshi ND, Hu Y, Guo J, McMahon JA, Carey DK, Xu C, Fang Q, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, Carr SA, Perrimon N, McMahon AP Open biology 35946312 Open Biol 2022 Aug
Shared and Distinctive Neighborhoods of Emerin and Lamin B Receptor Revealed by Proximity Labeling and Quantitative Proteomics. Cheng LC, Zhang X, Abhinav K, Nguyen JA, Baboo S, Martinez-Bartolomé S, Branon TC, Ting AY, Loose E, Yates JR 3rd, Gerace L Journal of proteome research 35972904 J Proteome Res 2022 Sep 2
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Gut microbiome of treatment-naïve MS patients of different ethnicities early in disease course. Ventura RE, Iizumi T, Battaglia T, Liu M, Perez-Perez GI, Herbert J, Blaser MJ Scientific reports 31705027 Sci Rep 2019 Nov 8
Severe lung disease characterized by lymphocytic bronchiolitis, alveolar ductitis, and emphysema (BADE) in industrial machine-manufacturing workers. Cummings KJ, Stanton ML, Nett RJ, Segal LN, Kreiss K, Abraham JL, Colby TV, Franko AD, Green FHY, Sanyal S, Tallaksen RJ, Wendland D, Bachelder VD, Boylstein RJ, Park JH, Cox-Ganser JM, Virji MA, Crawford JA, Green BJ, LeBouf RF, Blaser MJ, Weissman DN American journal of industrial medicine 31461179 Am J Ind Med 2019 Nov
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Obese Mice Losing Weight Due to trans-10,cis-12 Conjugated Linoleic Acid Supplementation or Food Restriction Harbor Distinct Gut Microbiota. den Hartigh LJ, Gao Z, Goodspeed L, Wang S, Das AK, Burant CF, Chait A, Blaser MJ The Journal of nutrition 29659960 J Nutr 2018 Apr 1
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The Intestinal Microbiome and Estrogen Receptor-Positive Female Breast Cancer. Kwa M, Plottel CS, Blaser MJ, Adams S Journal of the National Cancer Institute 27107051 J Natl Cancer Inst 2016 Aug
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Description of two novel members of the family Erysipelotrichaceae: Ileibacterium valens gen. nov., sp. nov. and Dubosiella newyorkensis, gen. nov., sp. nov., from the murine intestine, and emendation to the description of Faecalibaculum rodentium. Cox LM, Sohn J, Tyrrell KL, Citron DM, Lawson PA, Patel NB, Iizumi T, Perez-Perez GI, Goldstein EJC, Blaser MJ International journal of systematic and evolutionary microbiology 28100298 Int J Syst Evol Microbiol 2017 May
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Evaluating Serum Markers for Hormone Receptor-Negative Breast Cancer. Schummer M, Thorpe J, Giraldez MD, Bergan L, Tewari M, Urban N PloS one 26565788 PLoS One 2015
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Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens. March S, Ramanan V, Trehan K, Ng S, Galstian A, Gural N, Scull MA, Shlomai A, Mota MM, Fleming HE, Khetani SR, Rice CM, Bhatia SN Nature protocols 26584444 Nat Protoc 2015 Dec
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Single cell analysis of HCV-infected patient hepatocytes: the science is no longer science fiction. Sheahan TP, Rice CM Gastroenterology 24176873 Gastroenterology 2013 Dec
Pluripotent stem cell-derived hepatocyte-like cells. Schwartz RE, Fleming HE, Khetani SR, Bhatia SN Biotechnology advances 24440487 Biotechnol Adv 2014 Mar-Apr
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. Shlomai A, Schwartz RE, Ramanan V, Bhatta A, de Jong YP, Bhatia SN, Rice CM Proceedings of the National Academy of Sciences of the United States of America 25092305 Proc Natl Acad Sci U S A 2014 Aug 19
Characterization of nonprimate hepacivirus and construction of a functional molecular clone. Scheel TK, Kapoor A, Nishiuchi E, Brock KV, Yu Y, Andrus L, Gu M, Renshaw RW, Dubovi EJ, McDonough SP, Van de Walle GR, Lipkin WI, Divers TJ, Tennant BC, Rice CM Proceedings of the National Academy of Sciences of the United States of America 25646476 Proc Natl Acad Sci U S A 2015 Feb 17
Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- Mice. Andreo U, de Jong YP, Scull MA, Xiao JW, Vercauteren K, Quirk C, Mommersteeg MC, Bergaya S, Menon A, Fisher EA, Rice CM Cellular and molecular gastroenterology and hepatology 28936471 Cell Mol Gastroenterol Hepatol 2017 Nov
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A functional group-guided approach to aptamers for small molecules. Yang K, Mitchell NM, Banerjee S, Cheng Z, Taylor S, Kostic AM, Wong I, Sajjath S, Zhang Y, Stevens J, Mohan S, Landry DW, Worgall TS, Andrews AM, Stojanovic MN Science (New York, N.Y.) 37262137 Science 2023 Jun 2
Maximizing Electrochemical Information: A Perspective on Background-Inclusive Fast Voltammetry. Movassaghi CS, Alcañiz Fillol M, Kishida KT, McCarty G, Sombers LA, Wassum KM, Andrews AM Analytical chemistry 38597398 Anal Chem 2024 Apr 23
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Polyserotonin Nanoparticles as Multifunctional Materials for Biomedical Applications. Nakatsuka N, Hasani-Sadrabadi MM, Cheung KM, Young TD, Bahlakeh G, Moshaverinia A, Weiss PS, Andrews AM ACS nano 29664607 ACS Nano 2018 May 22
Scalable Fabrication of Quasi-One-Dimensional Gold Nanoribbons for Plasmonic Sensing. Zhao C, Xu X, Ferhan AR, Chiang N, Jackman JA, Yang Q, Liu W, Andrews AM, Cho NJ, Weiss PS Nano letters 32027140 Nano Lett 2020 Mar 11
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Protein design using structure-based residue preferences. Ding D, Shaw AY, Sinai S, Rollins N, Prywes N, Savage DF, Laub MT, Marks DS Nature communications 38388493 Nat Commun 2024 Feb 22
Co-evolution of interacting proteins through non-contacting and non-specific mutations. Ding D, Green AG, Wang B, Lite TV, Weinstein EN, Marks DS, Laub MT Nature ecology & evolution 35361892 Nat Ecol Evol 2022 May
Protein design and variant prediction using autoregressive generative models. Shin JE, Riesselman AJ, Kollasch AW, McMahon C, Simon E, Sander C, Manglik A, Kruse AC, Marks DS Nature communications 33893299 Nat Commun 2021 Apr 23
Rapid generation of potent antibodies by autonomous hypermutation in yeast. Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC bioRxiv : the preprint server for biology 33200136 bioRxiv 2020 Nov 11
Deep generative modeling of the human proteome reveals over a hundred novel genes involved in rare genetic disorders. Orenbuch R, Kollasch AW, Spinner HD, Shearer CA, Hopf TA, Franceschi D, Dias M, Frazer J, Marks DS Research square 38260496 Res Sq 2024 Jan 4
Continuous evolution of user-defined genes at 1-million-times the genomic mutation rate. Rix G, Williams RL, Spinner H, Hu VJ, Marks DS, Liu CC bioRxiv : the preprint server for biology 38014077 bioRxiv 2023 Nov 14
ProteinNPT: Improving Protein Property Prediction and Design with Non-Parametric Transformers. Notin P, Marks DS, Weitzman R, Gal Y bioRxiv : the preprint server for biology 38106034 bioRxiv 2023 Dec 7
ProteinGym: Large-Scale Benchmarks for Protein Design and Fitness Prediction. Notin P, Kollasch AW, Ritter D, van Niekerk L, Paul S, Spinner H, Rollins N, Shaw A, Weitzman R, Frazer J, Dias M, Franceschi D, Orenbuch R, Gal Y, Marks DS bioRxiv : the preprint server for biology 38106144 bioRxiv 2023 Dec 8
Rapidly inducible yeast surface display for antibody evolution with OrthoRep. Paulk AM, Williams RL, Liu CC bioRxiv : the preprint server for biology 38826191 bioRxiv 2024 May 24
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Guidelines for releasing a variant effect predictor. Livesey BJ, Badonyi M, Dias M, Frazer J, Kumar S, Lindorff-Larsen K, McCandlish DM, Orenbuch R, Shearer CA, Muffley L, Foreman J, Glazer AM, Lehner B, Marks DS, Roth FP, Rubin AF, Starita LM, Marsh JA ArXiv 38699161 ArXiv 2024 Apr 16
Antibodies expand the scope of angiotensin receptor pharmacology. Skiba MA, Sterling SM, Rawson S, Zhang S, Xu H, Jiang H, Nemeth GR, Gilman MSA, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Rockman HA, Barth P, Wingler LM, Kruse AC Nature chemical biology 38744986 Nat Chem Biol 2024 Dec
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An in silico method to assess antibody fragment polyreactivity. Harvey EP, Shin JE, Skiba MA, Nemeth GR, Hurley JD, Wellner A, Shaw AY, Miranda VG, Min JK, Liu CC, Marks DS, Kruse AC Nature communications 36477674 Nat Commun 2022 Dec 7
Antibodies Expand the Scope of Angiotensin Receptor Pharmacology. Skiba MA, Sterling SM, Rawson S, Gilman MSA, Xu H, Nemeth GR, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Wingler LM, Kruse AC bioRxiv : the preprint server for biology 37662341 bioRxiv 2023 Aug 24
Ultra-Efficient Integration of Gene Libraries onto Yeast Cytosolic Plasmids. Pisera A, Yu Y, Williams RL, Liu CC bioRxiv : the preprint server for biology 39651169 bioRxiv 2024 Nov 30
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An Atlas of Variant Effects to understand the genome at nucleotide resolution. Fowler DM, Adams DJ, Gloyn AL, Hahn WC, Marks DS, Muffley LA, Neal JT, Roth FP, Rubin AF, Starita LM, Hurles ME Genome biology 37394429 Genome Biol 2023 Jul 3
The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families. Smith JS, Hilibrand AS, Skiba MA, Dates AN, Calvillo-Miranda VG, Kruse AC Molecular pharmacology 38641412 Mol Pharmacol 2024 May 17
Learning from prepandemic data to forecast viral escape. Thadani NN, Gurev S, Notin P, Youssef N, Rollins NJ, Ritter D, Sander C, Gal Y, Marks DS Nature 37821700 Nature 2023 Oct
Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape. Muir DF, Asper GPR, Notin P, Posner JA, Marks DS, Keiser MJ, Pinney MM bioRxiv : the preprint server for biology 39484523 bioRxiv 2024 Oct 25
Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity. Boys IN, Johnson AG, Quinlan MR, Kranzusch PJ, Elde NC Cell reports 37494187 Cell Rep 2023 Aug 29
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Thg1 family 3'-5' RNA polymerases as tools for targeted RNA synthesis. Jayasinghe MI, Patel KJ, Jackman JE RNA (New York, N.Y.) 38997129 RNA 2024 Sep 16
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Grafting or pruning in the animal tree: lateral gene transfer and gene loss? Dunning Hotopp JC BMC genomics 29914363 BMC Genomics 2018 Jun 18
Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences. Kessler MD, Bateman NW, Conrads TP, Maxwell GL, Dunning Hotopp JC, O'Connor TD Cancer 30865299 Cancer 2019 Jun 15
Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics. Shetty AC, Mattick J, Chung M, McCracken C, Mahurkar A, Filler SG, Fraser CM, Rasko DA, Bruno VM, Dunning Hotopp JC Microbial genomics 31851607 Microb Genom 2020 Jan
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Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication. Scarpa M, Kapoor S, Tvedte ES, Doshi KA, Zou YS, Singh P, Lee JK, Chatterjee A, Ali MKM, Bromley RE, Hotopp JCD, Rassool FV, Baer MR Oncotarget 34504649 Oncotarget 2021 Aug 31
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Complete Genome Sequence of wAna, the Wolbachia Endosymbiont of Drosophila ananassae. Gasser MT, Chung M, Bromley RE, Nadendla S, Dunning Hotopp JC Microbiology resource announcements 31649084 Microbiol Resour Announc 2019 Oct 24
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The Complexities and Nuances of Analyzing the Genome of Drosophila ananassae and Its Wolbachia Endosymbiont. Dunning Hotopp JC, Klasson L G3 (Bethesda, Md.) 29301977 G3 (Bethesda) 2018 Jan 4
Distinguishing potential bacteria-tumor associations from contamination in a secondary data analysis of public cancer genome sequence data. Robinson KM, Crabtree J, Mattick JS, Anderson KE, Dunning Hotopp JC Microbiome 28118849 Microbiome 2017 Jan 25
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Aligner optimization increases accuracy and decreases compute times in multi-species sequence data. Robinson KM, Hawkins AS, Santana-Cruz I, Adkins RS, Shetty AC, Nagaraj S, Sadzewicz L, Tallon LJ, Rasko DA, Fraser CM, Mahurkar A, Silva JC, Dunning Hotopp JC Microbial genomics 29114401 Microb Genom 2017 Sep
Modeling the integration of bacterial rRNA fragments into the human cancer genome. Sieber KB, Gajer P, Dunning Hotopp JC BMC bioinformatics 27001685 BMC Bioinformatics 2016 Mar 21
Updated annotation and meta-analysis of Brugia malayi transcriptomics data reveals consistent transcriptional profiles across time and space with some study-specific differences in adult female worm transcriptional profiles. Holt CI, Dunning Hotopp JC PLoS neglected tropical diseases 39325836 PLoS Negl Trop Dis 2024 Sep
Total-Body Quantitative Parametric Imaging of Early Kinetics of (18)F-FDG. Feng T, Zhao Y, Shi H, Li H, Zhang X, Wang G, Price PM, Badawi RD, Cherry SR, Jones T Journal of nuclear medicine : official publication, Society of Nuclear Medicine 32948679 J Nucl Med 2021 May 10
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