Understanding the three-dimensional organization of the cell’s nucleus in space and time isn’t limited to studies of our genetic material, DNA

The 4DN program will continue to support research on the three-dimensional organization of the nucleus and how it shifts over time (the fourth…

The 4DN program has improved our understanding of how DNA is packaged and organized in the crowded space of the nucleus.

Providing scientists with the tools and resources to monitor the changes in gene activity from groups of cells in tumors as well as small changes in…

Building tools to map our DNA

Expanding our research toolbox

Understanding the relationship between chromatin architecture and biological development and how changes that occur early in development may impact…

Nearly 1% of all live births are impacted by congenital heart disease (CHD) and over 500 regions of our DNA are associated with cardiovascular…

DNA is organized inside the nucleus of a cell like a ball of cooked spaghetti. The organization of DNA can determine whether a gene encoded by the…

Dr. Andrew Belmont is a Professor of Cell and Developmental Biology as well as a Professor of Biophysics and Quantitative Biology at the University…