Program Snapshot
The Common Fund’s Molecular Libraries and Imaging program offers biomedical researchers access to the large-scale screening capacity necessary to identify small molecules that can be optimized as chemical probes to study the functions of genes, cells, and biochemical pathways in health and disease. They may also be used by researchers in the public and private sectors to validate new drug targets, which could then move into the drug-development pipeline. Components of the Molecular Libraries program include:
- The Molecular Libraries Probe Production Centers Network (MLPCN)
- PubChem
- Technology Development
Program Highlights
New Approach to Attacking Viruses: Researchers Discover Effective Inhibitor to Control Herpesvirus Infection and Reactivation
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Teaching Old Drugs New Tricks: Researchers Identify New Uses for a Class of Drugs to Treat Harmful Microbes
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Related Funding Initiatives
Please see new funding opportunities related to, but separate from, this
Common Fund program!
- PAR-13-134 High Throughput Screening (HTS) to Discover Chemical Probes (X01)
- PAR-13-135 High Throughput Screening (HTS) to Discover Chemical Probes (R03)
- PAR-12-058 Solicitation of Assays for High Throughput Screening (HTS) to Discover Chemical Probes (R01)
- PAR-12-059 Solicitation of Assays for High Throughput Screening (HTS) to Discover Chemical Probes (R21)
- PAR-11-319 Scalable Assays for Unbiased In Vitro Analysis of Neurobiological Function (R21/R33)
From Bench to Bedside: Therapeutic Candidate Targeting S1P1 Advances in Clinical Trials for Multiple Sclerosis
A compound initially discovered by the NIH Molecular Libraries Probe Production Center at The Scripps Research Institute, which is part of the NIH Common Fund Molecular Libraries Program, has been further developed by Receptos Inc. into a potential therapeutic agent that has successfully transitioned into Phase 2 and 3 clinical trials.
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Visit the Molecular Libraries and Imaging website…
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