Carbohydrates play critical roles in nearly every aspect of biology, but the complexity of carbohydrate chemistry makes glycan synthesis, sequencing, and study inaccessible to most biomedical researchers. The Glycoscience program aims to create new methodologies and resources in the study of glycans that are accessible to the broader research community. Read more…
First Annual Glycoscience Participating Investigators Meeting
The first Participating Investigators Meeting for the Glycoscience program was held on July 10, 2015, at the Natcher Conference Center on the NIH campus, Bethesda, MD. The meeting brought together Glycoscience investigators to discuss project proposals and begin to build a functioning consortium. The meeting also provided an opportunity for the awardees to learn more about the Glycoscience program, the Common Fund, and meet with NIH staff and leadership.
Related Funding Opportunities for Glycoscience tools and technology development. The National Institute of General Medical Sciences (NIGMS), the National Eye Institute (NEI), and the National Institute of Dental and Craniofacial Research (NIDCR) have announced SBIR/STTR programs to complement the Common Fund Glycoscience Program. Learn more about these opportunities here:
Congratulations to Dr. Carolyn Bertozzi, a Glycoscience grantee recently awarded the National Academy of Sciences 2016 award in Chemical Sciences. The NAS selected Dr. Bertozzi for inventing "a new class of chemical reactions, called bio-orthogonal chemistry, that lets scientists label biomolecules within living cells" and for pioneering "the use bio-orthogonal chemistry in the field of glycobiology, using the technique to study the glycans that decorate the surfaces of cells and change during inflammation or as a cell transforms from normal to malignant." Read more about this award here.
Glycoscience in Biology featured at the ASBMB Annual Meeting
The American Society for Biochemistry and Molecular Biology (ASBMB) hosted a Glycoscience in Biology Program at their 2016 annual meeting in San Diego, California. The focus was on how glycosylation impacts biology and how technological advances are providing novel insights into the roles of glycans in basic cellular processes and pathophysiologies. These sessions highlight multiple areas of research that stand to benefit from the tools and technologies being developed by the Common Fund's Glycoscience program.
Session topics included: the emerging role of O-GlcNAc in gene regulation, structural and enzymological advances in carbohydrate processing enzymes, chemical biology approaches in glycoscience, and the structural complexity of glycans in bacterial glycosylation and the microbiome.
Glycoscience Program Awardees Announced!
Approximately $10 million has been awarded to 23 research teams aiming to make carbohydrate chemistry and biology more accessible to the research community. These awards will develop tools to study, synthesize and analyze carbohydrates.
Read the press release announcing the launch of Glycoscience and other Common Fund programs designed to take aim at gaps in biomedical research.