Finding a Perfect Match – Matchmaking by the Molecular Libraries Program
March 7, 2011
A continent apart, synthetic chemist Dr. Gregory Fu, of MIT, Cambridge, MA and Dr. Ben Cravatt of Scripps, La Jolla, CA formed a productive scientific collaboration after a unique series of chemicals Dr. Fu donated to a public repository was found to inhibit a protein of interest to Dr. Cravatt.
Scripps Research and MIT scientists discover class of potent anti-cancer compounds
March 7, 2011
Working as part of a public program to screen compounds to find potential medicines and other biologically useful molecules, scientists from The Scripps Research Institute and Massachusetts Institute of Technology (MIT) have discovered an extremely potent class of potential anti-cancer and anti-neurodegenerative disorder compounds.
Going Underground in Search of New Drugs
February 1, 2011
Every few months, chemist Brian Bachmann sheds his white lab coat, collects his flashlight, helmet, surgical gloves and knotted rope, puts on old clothes and hiking boots and heads to a nearby cave.
Innovative Approaches to Study Complex Signaling Pathways in Cells
Researchers at John Hopkins University, led by Dr. Toru Komatsu and supported through the Common Fund’s Molecular Libraries and Imaging program, have developed a novel system to target and perturb specific molecular activities and communications pathways within cells. The technique may help elucidate the structure and function of complex signaling networks that perform basic functions within cells and may someday be targeted in disease therapies. The work was published in the journal Nature Methods (2010, 7(3):206-208).