The NIH Common Fund’s Metabolomics program aims to increase national capacity in metabolomics by supporting the development of next generation technologies to enhance the sensitivity and speed with which specific elements of the cellular metabolome can be identified and quantified, providing training and mentoring opportunities, increasing the inventory of chemically identifiable metabolites through the synthesis and availability of high quality reference standards, and by promoting data sharing and collaboration. Learn more here
Congratulations to Metabolomics program investigator Dr. Susan Sumner and colleagues who won the Best Paper in Toxicological Sciences award at the 2016 Society of Toxicology annual meeting! Dr. Sumner and colleagues used metabolomics studies in mice to better understand the side effects of drug commonly used to treat tuberculosis. More about the paper and the award can be found on the Society of Toxicology website.
Dr. Oliver Fiehn, director of the West Coast Metabolomics Center, recently coauthored a review that was recognized by Chemical and Engineering News as one of the ten most highly read mass spectrometry papers in Analytical Chemistry and Journal of Proteome Research. This list of highly influential papers can be found in the March 28th issue of C&E News. More information about Dr. Fiehn's review can be found here.
Antibiotics treatment leads to harmful infection by decreasing key metabolites A new paper from Metabolomics Program researcher Dr. Casey Theriot demonstrates the role that key metabolites play in preventing infection after antibiotic treatment. Read a brief description of the research.
Metabolomics Scientists Tie Metabolites to Lifespan in Mammals Research from a group including NIH Common Fund’s Metabolomics Program grantee Sun Hee Yim used the latest metabolomics techniques to look at a wide range of metabolites from 26 diverse species of mammals. They were able to correlate the levels of specific metabolites with the range of lifespans that exists across the mammals sampled, providing insight into biological mechanisms of longevity. Read more about this research.
Features of the Metabolomics Workbench highlighted in a recent publication
A new publication highlights the Metabolomics Workbench, created by the Metabolomics Program’s Data Repository and Coordination Center, and describes how to access resources from the Metabolomics Program. For additional information and to read a brief description of the research article.
Taming the Torrent of Metabolic Data
Metabolomics Program grantee, Dr. Oliver Fiehn at the NIH West Coast Metabolomics Center at UC Davis, and his colleagues in Japan, have developed open source software called MS-DIAL to help researchers analyze their untargeted metabolomics data. Read a brief description of the research.
Learn more about the Metabolomics Community
- Join the NIH Metabolomics Scientific Interest Group here.
- For Metabolomics data and resources, visit the UCSD Metabolomics Workbench.
The NIH Common Fund Metabolomics Program supports international data sharing through the MetabolomeXchange.
In April 2014, representatives from Australia, Canada, Germany, Japan, the Netherlands and the United States NIH Common Fund Metabolomics program met to discuss an international data exchange in metabolomics. The participants agreed to create a portal that would provide a network of coordinated and freely accessible metabolomics data collected from repositories around the world. As a result of this meeting and in collaboration with the European Bioinformatics Institute, the MetabolomeXchange was launched as an international index of freely accessible metabolomics data from around the world. As of December 2015 nearly 300 datasets are now available at http://metabolomexchange.org/ from three different repositories including the Common Fund Metabolomics Workbench.