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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Author Journal Name PubMedID Journal Abbreviation Publication Date PubMedLink
Iron(iii) chloride-catalyzed activation of glycosyl chlorides. Geringer SA, Demchenko AV Organic & biomolecular chemistry 30430182 Org Biomol Chem 2018 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/30430182
HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation. Panza M, Stine KJ, Demchenko AV Chemical communications (Cambridge, England) 31930269 Chem Commun (Camb) 2020 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/31930269
Investigation of Glycosyl Nitrates as Building Blocks for Chemical Glycosylation. Wang T, Singh Y, Stine KJ, Demchenko AV European journal of organic chemistry 31341403 European J Org Chem 2018 Dec 19 https://www.ncbi.nlm.nih.gov/pubmed/31341403
Triflic acid-mediated synthesis of thioglycosides. Escopy S, Singh Y, Demchenko AV Organic & biomolecular chemistry 31490529 Org Biomol Chem 2019 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/31490529
The chemical synthesis of human milk oligosaccharides: Lacto-N-tetraose (Galβ1→3GlcNAcβ1→3Galβ1→4Glc). Bandara MD, Stine KJ, Demchenko AV Carbohydrate research 31585319 Carbohydr Res 2019 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/31585319
Glycosyl nitrates in synthesis: streamlined access to glucopyranose building blocks differentiated at C-2. Wang T, Nigudkar SS, Yasomanee JP, Rath NP, Stine KJ, Demchenko AV Organic & biomolecular chemistry 29693690 Org Biomol Chem 2018 May 15 https://www.ncbi.nlm.nih.gov/pubmed/29693690
Intramolecular glycosylation. Jia XG, Demchenko AV Beilstein journal of organic chemistry 29062425 Beilstein J Org Chem 2017 https://www.ncbi.nlm.nih.gov/pubmed/29062425
Investigation of the H-bond-mediated aglycone delivery reaction in application to the synthesis of β-glucosides. Mannino MP, Yasomanee JP, Demchenko AV Carbohydrate research 30286335 Carbohydr Res 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30286335
Facile and robust methods for the regioselective acylation of N-acetylneuraminic acid. Shadrick M, Yu C, Geringer S, Ritter S, Behm A, Cox A, Lohman M, De Meo C New journal of chemistry = Nouveau journal de chimie 30147293 New J Chem 2018 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/30147293
Application of Porous Materials to Carbohydrate Chemistry and Glycoscience. Stine KJ Advances in carbohydrate chemistry and biochemistry 29173727 Adv Carbohydr Chem Biochem 2017 https://www.ncbi.nlm.nih.gov/pubmed/29173727
Extending the S-benzimidazolyl (SBiz) platform: N-alkylated SBiz glycosyl donors with the universal activation profile. Hasty SJ, Rath NP, Demchenko AV Pure and applied chemistry. Chimie pure et appliquee 29861508 Pure Appl Chem 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/29861508
Automated Chemical Oligosaccharide Synthesis: Novel Approach to Traditional Challenges. Panza M, Pistorio SG, Stine KJ, Demchenko AV Chemical reviews 29953217 Chem Rev 2018 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/29953217
OFox imidates as versatile glycosyl donors for chemical glycosylation. Nigudkar SS, Wang T, Pistorio SG, Yasomanee JP, Stine KJ, Demchenko AV Organic & biomolecular chemistry 27808325 Org Biomol Chem 2017 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/27808325
Manual and Automated Syntheses of the N-Linked Glycoprotein Core Glycans. Pistorio SG, Geringer SA, Stine KJ, Demchenko AV The Journal of organic chemistry 31066275 J Org Chem 2019 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/31066275
Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)(2) 3,6Galβ1 → 4Glc. Bandara MD, Stine KJ, Demchenko AV Organic & biomolecular chemistry 32048706 Org Biomol Chem 2020 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/32048706
A pH sensitive thiolated β-cyclodextrin-modified nanoporous gold for controlled release of doxorubicin. Neupane D, Bhattarai JK, Demchenko AV, Stine KJ Journal of drug delivery science and technology 32922527 J Drug Deliv Sci Technol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32922527
The development of a dedicated polymer support for the solid-phase oligosaccharide synthesis. Panza M , Neupane D , Stine KJ , Demchenko AV Chemical communications (Cambridge, England) 32785304 Chem Commun (Camb) 2020 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/32785304
Comparative Study on the Effects of Picoloyl Groups in Sialylations Based on Their Substitution Pattern. Jones B, Behm A, Shadrick M, Geringer SA, Escopy S, Lohman M, De Meo C The Journal of organic chemistry 31718181 J Org Chem 2019 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/31718181
Regenerative Glycosylation. Singh Y, Wang T, Geringer SA, Stine KJ, Demchenko AV The Journal of organic chemistry 29227649 J Org Chem 2018 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/29227649
A Streamlined Regenerative Glycosylation Reaction: Direct, Acid-Free Activation of Thioglycosides. Escopy S, Singh Y, Stine KJ, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 32804435 Chemistry 2021 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/32804435
HPLC-Assisted Automated Oligosaccharide Synthesis: Implementation of the Autosampler as a Mode of the Reagent Delivery. Pistorio SG, Nigudkar SS, Stine KJ, Demchenko AV The Journal of organic chemistry 27575052 J Org Chem 2016 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/27575052
Koenigs-Knorr Glycosylation Reaction Catalyzed by Trimethylsilyl Trifluoromethanesulfonate. Singh Y, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 30407673 Chemistry 2019 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/30407673
The chemical synthesis of human milk oligosaccharides: Lacto-N-neotetraose (Galβ1→4GlcNAcβ1→3Galβ1→4Glc). Bandara MD, Stine KJ, Demchenko AV Carbohydrate research 31319351 Carbohydr Res 2019 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31319351
Chemical Synthesis of Human Milk Oligosaccharides: Lacto-N-hexaose Galβ1→3GlcNAcβ1→3 [Galβ1→4GlcNAcβ1→6] Galβ1→4Glc. Bandara MD, Stine KJ, Demchenko AV The Journal of organic chemistry 31749363 J Org Chem 2019 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/31749363
HPLC-Based Automated Synthesis and Purification of Carbohydrates. Kashiwagi GA, Petrosilli L, Escopy S, Lay L, Stine KJ, De Meo C, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 38684455 Chemistry 2024 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/38684455
Synthesis of 2-azido-2-deoxy- and 2-acetamido-2-deoxy-D-manno derivatives as versatile building blocks. Alex C, Visansirikul S, Zhang Y, Yasomanee JP, Codee J, Demchenko AV Carbohydrate research 31901454 Carbohydr Res 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31901454
Immobilization of glycans on solid surfaces for application in glycomics. O'Neil CL, Stine KJ, Demchenko AV Journal of carbohydrate chemistry 30505067 J Carbohydr Chem 2018 https://www.ncbi.nlm.nih.gov/pubmed/30505067
Bromine-Promoted Glycosidation of Conformationally Superarmed Thioglycosides. Panza M, Civera M, Yasomanee JP, Belvisi L, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 31286579 Chemistry 2019 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/31286579
Synthesis of carbohydrate building blocks via regioselective uniform protection/deprotection strategies. Wang T, Demchenko AV Organic & biomolecular chemistry 31044205 Org Biomol Chem 2019 May 28 https://www.ncbi.nlm.nih.gov/pubmed/31044205
Biochemical characterization of Helicobacter pylori α1-3-fucosyltransferase and its application in the synthesis of fucosylated human milk oligosaccharides. Bai J, Wu Z, Sugiarto G, Gadi MR, Yu H, Li Y, Xiao C, Ngo A, Zhao B, Chen X, Guan W Carbohydrate research 31132553 Carbohydr Res 2019 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/31132553
Regioselective One-Pot Multienzyme (OPME) Chemoenzymatic Strategies for Systematic Synthesis of Sialyl Core 2 Glycans. Santra A, Li Y, Ghosh T, Li R, Yu H, Chen X ACS catalysis 31304048 ACS Catal 2019 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/31304048
One-pot multienzyme (OPME) chemoenzymatic synthesis of brain ganglioside glycans with human ST3GAL II expressed in E. coli. Yang X, Yu H, Yang X, Kooner AS, Yuan Y, Luu B, Chen X ChemCatChem 35784007 ChemCatChem 2022 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/35784007
Recent progress in synthesis of carbohydrates with sugar nucleotide-dependent glycosyltransferases. Na L, Li R, Chen X Current opinion in chemical biology 33310623 Curr Opin Chem Biol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33310623
Strategies for chemoenzymatic synthesis of carbohydrates. Li W, McArthur JB, Chen X Carbohydrate research 30529493 Carbohydr Res 2019 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/30529493
Chemoenzymatic synthesis of para-nitrophenol (pNP)-tagged α2-8-sialosides and high-throughput substrate specificity studies of α2-8-sialidases. Tasnima N, Yu H, Li Y, Santra A, Chen X Organic & biomolecular chemistry 27924345 Org Biomol Chem 2016 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/27924345
Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. Kooner AS, Yu H, Chen X Frontiers in immunology 31555264 Front Immunol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31555264
A Bacterial β1-3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-N-tetraose (LNT) and Its Fucosides. McArthur JB, Yu H, Chen X ACS catalysis 33408950 ACS Catal 2019 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/33408950
Catalytic Cycle of Neisseria meningitidis CMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography. Matthews MM, McArthur JB, Li Y, Yu H, Chen X, Fisher AJ Biochemistry 31583886 Biochemistry 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31583886
H. pylori α1-3/4-fucosyltransferase (Hp3/4FT)-catalyzed one-pot multienzyme (OPME) synthesis of Lewis antigens and human milk fucosides. Yu H, Li Y, Wu Z, Li L, Zeng J, Zhao C, Wu Y, Tasnima N, Wang J, Liu H, Gadi MR, Guan W, Wang PG, Chen X Chemical communications (Cambridge, England) 28936496 Chem Commun (Camb) 2017 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/28936496
Substrate and Process Engineering for Biocatalytic Synthesis and Facile Purification of Human Milk Oligosaccharides. Bai Y, Yang X, Yu H, Chen X ChemSusChem 35100486 ChemSusChem 2022 May 6 https://www.ncbi.nlm.nih.gov/pubmed/35100486
Recent progress in chemical synthesis of bacterial surface glycans. Li R, Yu H, Chen X Current opinion in chemical biology 32920523 Curr Opin Chem Biol 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32920523
Chemoenzymatic Synthesis and Facile Purification of Gangliosides. Bai Y, Yu H, Chen X Current protocols 33760402 Curr Protoc 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33760402
Converting Pasteurella multocidaα2-3-sialyltransferase 1 (PmST1) to a regioselective α2-6-sialyltransferase by saturation mutagenesis and regioselective screening. McArthur JB, Yu H, Zeng J, Chen X Organic & biomolecular chemistry 28134951 Org Biomol Chem 2017 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/28134951
Highly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc(4)βCer. Santra A, Li Y, Yu H, Slack TJ, Wang PG, Chen X Chemical communications (Cambridge, England) 28695219 Chem Commun (Camb) 2017 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/28695219
Chemoenzymatic synthesis of Neu5Ac9NAc-containing α2-3- and α2-6-linked sialosides and their use for sialidase substrate specificity studies. Li W, Xiao A, Li Y, Yu H, Chen X Carbohydrate research 28961426 Carbohydr Res 2017 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/28961426
Facile chemoenzymatic synthesis of Lewis a (Le(a)) antigen in gram-scale and sialyl Lewis a (sLe(a)) antigens containing diverse sialic acid forms. Tasnima N, Yu H, Yan X, Li W, Xiao A, Chen X Carbohydrate research 30562693 Carbohydr Res 2019 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/30562693
Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens. Yu H, Santra A, Li Y, McArthur JB, Ghosh T, Yang X, Wang PG, Chen X Organic & biomolecular chemistry 29789847 Org Biomol Chem 2018 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/29789847
Process Engineering and Glycosyltransferase Improvement for Short Route Chemoenzymatic Total Synthesis of GM1 Gangliosides. Yu H, Zhang L, Yang X, Bai Y, Chen X Chemistry (Weinheim an der Bergstrasse, Germany) 36596720 Chemistry 2023 May 2 https://www.ncbi.nlm.nih.gov/pubmed/36596720
Chemoenzymatic Synthesis of N-Acetyl Analogues of 9-O-Acetylated b-Series Gangliosides. Yu H, Zheng Z, Zhang L, Yang X, Varki A, Chen X Tetrahedron 37981995 Tetrahedron 2023 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/37981995
Sialidase-catalyzed one-pot multienzyme (OPME) synthesis of sialidase transition-state analogue inhibitors. Xiao A, Li Y, Li X, Santra A, Yu H, Li W, Chen X ACS catalysis 29713561 ACS Catal 2018 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/29713561
Chemoenzymatic Total Synthesis of GM3 Gangliosides Containing Different Sialic Acid Forms and Various Fatty Acyl Chains. Yu H, Gadi MR, Bai Y, Zhang L, Li L, Yin J, Wang PG, Chen X The Journal of organic chemistry 34152144 J Org Chem 2021 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/34152144
Directed Evolution of Therapeutic Antibodies Targeting Glycosylation in Cancer. Amon R, Rosenfeld R, Perlmutter S, Grant OC, Yehuda S, Borenstein-Katz A, Alcalay R, Marshanski T, Yu H, Diskin R, Woods RJ, Chen X, Padler-Karavani V Cancers 33007970 Cancers (Basel) 2020 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/33007970
Methods for 2-Deoxyglycoside Synthesis. Bennett CS, Galan MC Chemical reviews 29953219 Chem Rev 2018 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/29953219
Versatile Glycosyl Sulfonates in β-Selective C-Glycosylation. Ling J, Bennett CS Angewandte Chemie (International ed. in English) 31880395 Angew Chem Int Ed Engl 2020 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/31880395
Recent Developments in Stereoselective Chemical Glycosylation. Ling J, Bennett CS Asian journal of organic chemistry 31534883 Asian J Org Chem 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31534883
An Improved Approach to the Direct Construction of 2-Deoxy-β-Linked Sugars: Applications to Oligosaccharide Synthesis. Lloyd D, Bennett CS Chemistry (Weinheim an der Bergstrasse, Germany) 29572995 Chemistry 2018 May 28 https://www.ncbi.nlm.nih.gov/pubmed/29572995
Modular continuous flow synthesis of orthogonally protected 6-deoxy glucose glycals. Yalamanchili S, Nguyen TV, Pohl NLB, Bennett CS Organic & biomolecular chemistry 32293636 Org Biomol Chem 2020 May 6 https://www.ncbi.nlm.nih.gov/pubmed/32293636
Automated, Multistep Continuous-Flow Synthesis of 2,6-Dideoxy and 3-Amino-2,3,6-trideoxy Monosaccharide Building Blocks. Yalamanchili S, Nguyen TA, Zsikla A, Stamper G, DeYong AE, Florek J, Vasquez O, Pohl NLB, Bennett CS Angewandte Chemie (International ed. in English) 34463017 Angew Chem Int Ed Engl 2021 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/34463017
Reagent-Controlled α-Selective Dehydrative Glycosylation of 2,6-Dideoxy Sugars: Construction of the Arugomycin Tetrasaccharide. Romeo JR, McDermott L, Bennett CS Organic letters 32281384 Org Lett 2020 May 1 https://www.ncbi.nlm.nih.gov/pubmed/32281384
Reagent Controlled Direct Dehydrative Glycosylation with 2-Deoxy Sugars: Construction of the Saquayamycin Z Pentasaccharide. Mizia JC, Bennett CS Organic letters 31305082 Org Lett 2019 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/31305082
Challenges in the Conversion of Manual Processes to Machine-Assisted Syntheses: Activation of Thioglycoside Donors with Aryl(trifluoroethyl)iodonium Triflimide. Saliba RC, Wooke ZJ, Nieves GA, Chu AA, Bennett CS, Pohl NLB Organic letters 29336575 Org Lett 2018 Feb 2 https://www.ncbi.nlm.nih.gov/pubmed/29336575
Rapid de Novo Preparation of 2,6-Dideoxy Sugar Libraries through Gold-Catalyzed Homopropargyl Orthoester Cyclization. Yalamanchili S, Miller W, Chen X, Bennett CS Organic letters 31755271 Org Lett 2019 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/31755271
Glycosyl Sulfonates Beyond Triflates. Bennett CS Chemical record (New York, N.Y.) 34142755 Chem Rec 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34142755
Matching Glycosyl Donor Reactivity to Sulfonate Leaving Group Ability Permits S(N)2 Glycosylations. Zhuo MH, Wilbur DJ, Kwan EE, Bennett CS Journal of the American Chemical Society 31550879 J Am Chem Soc 2019 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/31550879
Synthesis of the Hexasaccharide Fragment of Landomycin A Using a Mild, Reagent-Controlled Approach. Yalamanchili S, Lloyd D, Bennett CS Organic letters 31021647 Org Lett 2019 May 17 https://www.ncbi.nlm.nih.gov/pubmed/31021647
Expanding Glycomic Investigations through Thiol-Derivatized Glycans. Hurst RD, Nieves A, Brichacek M Molecules (Basel, Switzerland) 36838944 Molecules 2023 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/36838944
Transformation of aldehydes into nitriles in an aqueous medium using O-phenylhydroxylamine as the nitrogen source. Cheewawisuttichai T, Hurst RD, Brichacek M Carbohydrate research 33761407 Carbohydr Res 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33761407
Development of a multifunctional neoglycoside auxiliary for applications in glycomics research. Cheewawisuttichai T, Brichacek M Organic & biomolecular chemistry 34264248 Org Biomol Chem 2021 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/34264248
Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy. Liu L, Prudden AR, Capicciotti CJ, Bosman GP, Yang JY, Chapla DG, Moremen KW, Boons GJ Nature chemistry 30532014 Nat Chem 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30532014
Emerging structural insights into glycosyltransferase-mediated synthesis of glycans. Moremen KW, Haltiwanger RS Nature chemical biology 31427814 Nat Chem Biol 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31427814
Chemoenzymatic Synthesis of Asymmetrical Multi-Antennary N-Glycans to Dissect Glycan-Mediated Interactions between Human Sperm and Oocytes. Chinoy ZS, Friscourt F, Capicciotti CJ, Chiu P, Boons GJ Chemistry (Weinheim an der Bergstrasse, Germany) 29603480 Chemistry 2018 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/29603480
Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses. Broszeit F, van Beek RJ, Unione L, Bestebroer TM, Chapla D, Yang JY, Moremen KW, Herfst S, Fouchier RAM, de Vries RP, Boons GJ Nature communications 34521834 Nat Commun 2021 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/34521834
Improved isolation and characterization procedure of sialylglycopeptide from egg yolk powder. Liu L, Prudden AR, Bosman GP, Boons GJ Carbohydrate research 29096185 Carbohydr Res 2017 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/29096185
An automated platform for the enzyme-mediated assembly of complex oligosaccharides. Li T, Liu L, Wei N, Yang JY, Chapla DG, Moremen KW, Boons GJ Nature chemistry 30792508 Nat Chem 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30792508
Chemoenzymatic Synthesis of Campylobacter jejuni Lipo-oligosaccharide Core Domains to Examine Guillain-Barré Syndrome Serum Antibody Specificities. Li T, Wolfert MA, Wei N, Huizinga R, Jacobs BC, Boons GJ Journal of the American Chemical Society 33164488 J Am Chem Soc 2020 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/33164488
Guillain-Barré syndrome: expanding the concept of molecular mimicry. Laman JD, Huizinga R, Boons GJ, Jacobs BC Trends in immunology 35256276 Trends Immunol 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35256276
Appropriate aglycone modification significantly expands the glycan substrate acceptability of α1,6-fucosyltransferase (FUT8). Zhang R, Yang Q, Boruah BM, Zong G, Li C, Chapla D, Yang JY, Moremen KW, Wang LX The Biochemical journal 33734311 Biochem J 2021 Apr 30 https://www.ncbi.nlm.nih.gov/pubmed/33734311
Chemoenzymatic Tagging of Tn/TF/STF Antigens in Living Systems. Yang Y, Chen M, Wu M, Hong S, Gao B, Liu Y, Yu C, Young TS, Chapla DG, Yang JY, Cappiello JR, Li JP, Sharpless KB, Moremen KW, Wu P Israel journal of chemistry 38737670 Isr J Chem 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/38737670
Phenanthroline-Catalyzed Stereoselective Formation of α-1,2-cis 2-Deoxy-2-Fluoro Glycosides. DeMent PM, Liu C, Wakpal J, Schaugaard RN, Schlegel HB, Nguyen HM ACS catalysis 34336371 ACS Catal 2021 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/34336371
Enantio- and Diastereoselective Synthesis of Hydroxy Bis(boronates) via Cu-Catalyzed Tandem Borylation/1,2-Addition. Green JC, Joannou MV, Murray SA, Zanghi JM, Meek SJ ACS catalysis 29520326 ACS Catal 2017 https://www.ncbi.nlm.nih.gov/pubmed/29520326
Diastereoselective sp(3) C-O Bond Formation via Visible Light-Induced, Copper-Catalyzed Cross-Couplings of Glycosyl Bromides with Aliphatic Alcohols. Yu F, Dickson JL, Loka RS, Xu H, Schaugaard RN, Schlegel HB, Luo L, Nguyen HM ACS catalysis 34168901 ACS Catal 2020 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/34168901
Phenanthroline-Catalyzed Stereoretentive Glycosylations. Yu F, Li J, DeMent PM, Tu YJ, Schlegel HB, Nguyen HM Angewandte Chemie (International ed. in English) 30920099 Angew Chem Int Ed Engl 2019 May 20 https://www.ncbi.nlm.nih.gov/pubmed/30920099
Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes. Wu Z, Liu Y, Ma C, Li L, Bai J, Byrd-Leotis L, Lasanajak Y, Guo Y, Wen L, Zhu H, Song J, Li Y, Steinhauer DA, Smith DF, Zhao B, Chen X, Guan W, Wang PG Organic & biomolecular chemistry 27752690 Org Biomol Chem 2016 Nov 29 https://www.ncbi.nlm.nih.gov/pubmed/27752690
Site-Directed Glycosylation of Peptide/Protein with Homogeneous O-Linked Eukaryotic N-Glycans. Wu Z, Jiang K, Zhu H, Ma C, Yu Z, Li L, Guan W, Liu Y, Zhu H, Chen Y, Li S, Li J, Cheng J, Zhang L, Wang PG Bioconjugate chemistry 27529638 Bioconjug Chem 2016 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/27529638
Chemoenzymatic Synthesis of a Library of Human Milk Oligosaccharides. Xiao Z, Guo Y, Liu Y, Li L, Zhang Q, Wen L, Wang X, Kondengaden SM, Wu Z, Zhou J, Cao X, Li X, Ma C, Wang PG The Journal of organic chemistry 27305319 J Org Chem 2016 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/27305319
A One-Step Chemoenzymatic Labeling Strategy for Probing Sialylated Thomsen-Friedenreich Antigen. Wen L, Liu D, Zheng Y, Huang K, Cao X, Song J, Wang PG ACS central science 29721527 ACS Cent Sci 2018 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/29721527
Facile Chemoenzymatic Synthesis of O-Mannosyl Glycans. Wang S, Zhang Q, Chen C, Guo Y, Gadi MR, Yu J, Westerlind U, Liu Y, Cao X, Wang PG, Li L Angewandte Chemie (International ed. in English) 29732660 Angew Chem Int Ed Engl 2018 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/29732660
Sialic acid linkage-specific permethylation for improved profiling of protein glycosylation by MALDI-TOF MS. Jiang K, Zhu H, Li L, Guo Y, Gashash E, Ma C, Sun X, Li J, Zhang L, Wang PG Analytica chimica acta 28693729 Anal Chim Acta 2017 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/28693729
Chemoenzymatic modular assembly of O-GalNAc glycans for functional glycomics. Wang S, Chen C, Gadi MR, Saikam V, Liu D, Zhu H, Bollag R, Liu K, Chen X, Wang F, Wang PG, Ling P, Guan W, Li L Nature communications 34117223 Nat Commun 2021 Jun 11 https://www.ncbi.nlm.nih.gov/pubmed/34117223
Identifying Sialylation Linkages at the Glycopeptide Level by Glycosyltransferase Labeling Assisted Mass Spectrometry (GLAMS). Zhu H, Wang S, Liu D, Ding L, Chen C, Liu Y, Wu Z, Bollag R, Liu K, Alexander WM, Yin J, Ma C, Li L, Wang PG Analytical chemistry 32271005 Anal Chem 2020 May 5 https://www.ncbi.nlm.nih.gov/pubmed/32271005
Machine-Driven Chemoenzymatic Synthesis of Glycopeptide. Zhang J, Liu D, Saikam V, Gadi MR, Gibbons C, Fu X, Song H, Yu J, Kondengaden SM, Wang PG, Wen L Angewandte Chemie (International ed. in English) 32677091 Angew Chem Int Ed Engl 2020 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/32677091
Biochemical characterization of an α1,2-colitosyltransferase from Escherichia coli O55:H7. Wu Z, Zhao G, Li T, Qu J, Guan W, Wang J, Ma C, Li X, Zhao W, Wang PG, Li L Glycobiology 26703456 Glycobiology 2016 May https://www.ncbi.nlm.nih.gov/pubmed/26703456
An OGA-Resistant Probe Allows Specific Visualization and Accurate Identification of O-GlcNAc-Modified Proteins in Cells. Li J, Wang J, Wen L, Zhu H, Li S, Huang K, Jiang K, Li X, Ma C, Qu J, Parameswaran A, Song J, Zhao W, Wang PG ACS chemical biology 27622469 ACS Chem Biol 2016 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/27622469
Microarray analyses of closely related glycoforms reveal different accessibilities of glycan determinants on N-glycan branches. Li L, Guan W, Zhang G, Wu Z, Yu H, Chen X, Wang PG Glycobiology 32026940 Glycobiology 2020 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/32026940
Decoding glycan protein interactions by a new class of asymmetric N-glycans. Wu Z, Liu Y, Li L, Wan XF, Zhu H, Guo Y, Wei M, Guan W, Wang PG Organic & biomolecular chemistry 29043371 Org Biomol Chem 2017 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/29043371
Chemoenzymatic synthesis of the bacterial polysaccharide repeating unit undecaprenyl pyrophosphate and its analogs. Li L, Woodward RL, Han W, Qu J, Song J, Ma C, Wang PG Nature protocols 27336706 Nat Protoc 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27336706
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Writing and erasing O-GlcNAc from target proteins in cells. Ge Y, Woo CM Biochemical Society transactions 34783346 Biochem Soc Trans 2021 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/34783346
O-GlcNAc Engineering on a Target Protein in Cells with Nanobody-OGT and Nanobody-splitOGA. Ramirez DH, Ge Y, Woo CM Current protocols 33950562 Curr Protoc 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33950562
4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase. Jackson EG, Cutolo G, Yang B, Yarravarapu N, Burns MWN, Bineva-Todd G, Roustan C, Thoden JB, Lin-Jones HM, van Kuppevelt TH, Holden HM, Schumann B, Kohler JJ, Woo CM, Pratt MR ACS chemical biology 34931806 ACS Chem Biol 2022 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/34931806
GlycoFibroTyper: A Novel Method for the Glycan Analysis of IgG and the Development of a Biomarker Signature of Liver Fibrosis. Scott DA, Wang M, Grauzam S, Pippin S, Black A, Angel PM, Drake RR, Castellino S, Kono Y, Rockey DC, Mehta AS Frontiers in immunology 35197973 Front Immunol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35197973
A Rapid Array-Based Approach to N-Glycan Profiling of Cultured Cells. Angel PM, Saunders J, Clift CL, White-Gilbertson S, Voelkel-Johnson C, Yeh E, Mehta A, Drake RR Journal of proteome research 31535553 J Proteome Res 2019 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/31535553
Development of an Antibody-Based Platform for the Analysis of Immune Cell-Specific N-linked Glycosylation. Dressman JW, McDowell CT, Lu X, Angel PM, Drake RR, Mehta AS Analytical chemistry 37293957 Anal Chem 2023 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/37293957
Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression. Young LEA, Nietert PJ, Stubler R, Kittrell CG, Grimsley G, Lewin DN, Mehta AS, Hajar C, Wang K, O'Quinn EC, Angel PM, Wallace K, Drake RR Frontiers in pharmacology 38273829 Front Pharmacol 2023 https://www.ncbi.nlm.nih.gov/pubmed/38273829
On the Cutting Edge of Translational Research. Angel PM Clinical chemistry 33230521 Clin Chem 2021 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/33230521
Multiplexed imaging mass spectrometry of the extracellular matrix using serial enzyme digests from formalin-fixed paraffin-embedded tissue sections. Clift CL, Drake RR, Mehta A, Angel PM Analytical and bioanalytical chemistry 33206215 Anal Bioanal Chem 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33206215
Antibody Panel Based N-Glycan Imaging for N-Glycoprotein Biomarker Discovery. Black AP, Angel PM, Drake RR, Mehta AS Current protocols in protein science 31721442 Curr Protoc Protein Sci 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31721442
Spatial N-glycomics of the human aortic valve in development and pediatric endstage congenital aortic valve stenosis. Angel PM, Drake RR, Park Y, Clift CL, West C, Berkhiser S, Hardiman G, Mehta AS, Bichell DP, Su YR Journal of molecular and cellular cardiology 33516683 J Mol Cell Cardiol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33516683
Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen-Defined Pancreatic Cancer Tissues. McDowell CT, Klamer Z, Hall J, West CA, Wisniewski L, Powers TW, Angel PM, Mehta AS, Lewin DN, Haab BB, Drake RR Molecular & cellular proteomics : MCP 33581409 Mol Cell Proteomics 2021 https://www.ncbi.nlm.nih.gov/pubmed/33581409
Applications and continued evolution of glycan imaging mass spectrometry. McDowell CT, Lu X, Mehta AS, Angel PM, Drake RR Mass spectrometry reviews 34392557 Mass Spectrom Rev 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/34392557
Protease-dependent defects in N-cadherin processing drive PMM2-CDG pathogenesis. Klaver EJ, Dukes-Rimsky L, Kumar B, Xia ZJ, Dang T, Lehrman MA, Angel P, Drake RR, Freeze HH, Steet R, Flanagan-Steet H JCI insight 34784297 JCI Insight 2021 Dec 22 https://www.ncbi.nlm.nih.gov/pubmed/34784297
Set Up for Failure: Pre-Existing Autoantibodies in Lung Transplant. McQuiston A, Emtiazjoo A, Angel P, Machuca T, Christie J, Atkinson C Frontiers in immunology 34456920 Front Immunol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34456920
Rapid N-Glycan Profiling of Serum and Plasma by a Novel Slide-Based Imaging Mass Spectrometry Workflow. Blaschke CRK, Black AP, Mehta AS, Angel PM, Drake RR Journal of the American Society for Mass Spectrometry 32809822 J Am Soc Mass Spectrom 2020 Dec 2 https://www.ncbi.nlm.nih.gov/pubmed/32809822
Array-Based N-Glycan Profiling of Cells in Culture. Angel PM, Mehta AS, Drake RR Methods in molecular biology (Clifton, N.J.) 33908018 Methods Mol Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33908018
Collagen fiber regulation in human pediatric aortic valve development and disease. Clift CL, Su YR, Bichell D, Jensen Smith HC, Bethard JR, Norris-Caneda K, Comte-Walters S, Ball LE, Hollingsworth MA, Mehta AS, Drake RR, Angel PM Scientific reports 33963260 Sci Rep 2021 May 7 https://www.ncbi.nlm.nih.gov/pubmed/33963260
The role of neuraminidase in TLR4-MAPK signalling and the release of cytokines by lupus serum-stimulated mesangial cells. Sundararaj K, Rodgers J, Angel P, Wolf B, Nowling TK Immunology 33314123 Immunology 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33314123
Optimization of Multiple Glycosidase and Chemical Stabilization Strategies for N-Glycan Isomer Detection by Mass Spectrometry Imaging in Formalin-Fixed, Paraffin-Embedded Tissues. West CA, Lu X, Grimsley G, Norris-Caneda K, Mehta AS, Angel PM, Drake RR Methods in molecular biology (Clifton, N.J.) 33908016 Methods Mol Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33908016
Bioorthogonal Chemical Labeling Probes Targeting Sialic Acid Isomers for N-Glycan MALDI Imaging Mass Spectrometry of Tissues, Cells, and Biofluids. Lu X, McDowell CT, Blaschke CRK, Liu L, Grimsley G, Wisniewski L, Gao C, Mehta AS, Haab BB, Angel PM, Drake RR Analytical chemistry 37126482 Anal Chem 2023 May 16 https://www.ncbi.nlm.nih.gov/pubmed/37126482
An N-glycome tissue atlas of 15 human normal and cancer tissue types determined by MALDI-imaging mass spectrometry. Wallace EN, West CA, McDowell CT, Lu X, Bruner E, Mehta AS, Aoki-Kinoshita KF, Angel PM, Drake RR Scientific reports 38177192 Sci Rep 2024 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/38177192
Pro-inflammatory IgG1 N-glycan signature correlates with primary graft dysfunction onset in COPD patients. McQuiston A, Scott D, Nord D, Langerude L, Pelaez A, Machuca T, Mehta A, Drake RR, Christie JD, Angel P, Atkinson C Transplant immunology 34767945 Transpl Immunol 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/34767945
Multi-omic landscape of human gliomas from diagnosis to treatment and recurrence. Piyadasa H, Oberlton B, Ribi M, Ranek JS, Averbukh I, Leow K, Amouzgar M, Liu CC, Greenwald NF, McCaffrey EF, Kumar R, Ferrian S, Tsai AG, Filiz F, Fullaway CC, Bosse M, Varra SR, Kong A, Sowers C, Gephart MH, Nuñez-Perez P, Yang E, Travers M, Schachter MJ, Liang S, Santi MR, Bucktrout S, Gherardini PF, Cole K, Barish ME, Brown CE, Oldridge DA, Drake RR, Phillips JJ, Okada H, Prins R, Bendall SC, Angelo M bioRxiv : the preprint server for biology 40161803 bioRxiv 2025 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/40161803
Integrating age, BMI, and serum N-glycans detected by MALDI mass spectrometry to classify suspicious mammogram findings as benign lesions or breast cancer. Blaschke CRK, Hill EG, Mehta AS, Angel PM, Laronga C, Drake RR Scientific reports 36460712 Sci Rep 2022 Dec 2 https://www.ncbi.nlm.nih.gov/pubmed/36460712
Evaluation of Therapeutic Collagen-Based Biomaterials in the Infarcted Mouse Heart by Extracellular Matrix Targeted MALDI Imaging Mass Spectrometry. Clift CL, McLaughlin S, Muñoz M, Suuronen EJ, Rotstein BH, Mehta AS, Drake RR, Alarcon EI, Angel PM Journal of the American Society for Mass Spectrometry 34713699 J Am Soc Mass Spectrom 2021 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/34713699
Glycan Imaging Mass Spectrometry: Progress in Developing Clinical Diagnostic Assays for Tissues, Biofluids, and Cells. Blaschke CRK, McDowell CT, Black AP, Mehta AS, Angel PM, Drake RR Clinics in laboratory medicine 34020762 Clin Lab Med 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34020762
Metabolic Markers and Association of Biological Sex in Lupus Nephritis. Wolf B, Blaschke CRK, Mungaray S, Weselman BT, Stefanenko M, Fedoriuk M, Bai H, Rodgers J, Palygin O, Drake RR, Nowling TK International journal of molecular sciences 38003679 Int J Mol Sci 2023 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/38003679
Determining the N-Glycan and Collagen/Extracellular Matrix Protein Compositions in a Novel Outcome Cohort of Prostate Cancer Tissue Microarrays Using MALDI-MSI. Hartig JP, Bejar K, Young LEA, Grimsley G, Bethard JR, Troyer DA, Hernandez J, Wu JD, Ippolito JE, Ball LE, Gelfond JAL, Johnson-Pais TL, Mehta AS, Leach RJ, Angel PM, Drake RR Cancer research communications 39347566 Cancer Res Commun 2024 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/39347566
Roles of glycoconjugates in neural patterning in C. elegans. Bülow HE Current topics in developmental biology 33992159 Curr Top Dev Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33992159
Imaging Glycosaminoglycan Modification Patterns In Vivo. Bülow HE Methods in molecular biology (Clifton, N.J.) 34626406 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/34626406
Heparan sulfates and heparan sulfate proteoglycans in hematopoiesis. Piszczatowski RT, Bülow HE, Steidl U Blood 38639475 Blood 2024 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/38639475
Aurora Kinase A Inhibition: A Mega-Hit for Myelofibrosis Therapy? Piszczatowski RT, Steidl U Clinical cancer research : an official journal of the American Association for Cancer Research 31196854 Clin Cancer Res 2019 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/31196854
The HSPG syndecan is a core organizer of cholinergic synapses. Zhou X, Vachon C, Cizeron M, Romatif O, Bülow HE, Jospin M, Bessereau JL The Journal of cell biology 34213535 J Cell Biol 2021 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/34213535
A glycan-based approach to cell characterization and isolation: Hematopoiesis as a paradigm. Piszczatowski RT, Schwenger E, Sundaravel S, Stein CM, Liu Y, Stanley P, Verma A, Zheng D, Seidel RD, Almo SC, Townley RA, Bülow HE, Steidl U The Journal of experimental medicine 36066492 J Exp Med 2022 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/36066492
HSMotifDiscover: identification of motifs in sequences composed of non-single-letter elements. Singh VK, Misra R, Almo SC, Steidl UG, Bülow HE, Zheng D Bioinformatics (Oxford, England) 35771633 Bioinformatics 2022 Aug 10 https://www.ncbi.nlm.nih.gov/pubmed/35771633
Ganglioside Extraction, Purification and Profiling. Porter MJ, Zhang GL, Schnaar RL Journal of visualized experiments : JoVE 33779615 J Vis Exp 2021 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/33779615
Siglec Ligands. Gonzalez-Gil A, Schnaar RL Cells 34065256 Cells 2021 May 20 https://www.ncbi.nlm.nih.gov/pubmed/34065256
Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts. Ilic K, Lin X, Malci A, Stojanović M, Puljko B, Rožman M, Vukelić Ž, Heffer M, Montag D, Schnaar RL, Kalanj-Bognar S, Herrera-Molina R, Mlinac-Jerkovic K International journal of molecular sciences 34948386 Int J Mol Sci 2021 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/34948386
Gangliosides as Siglec ligands. Schnaar RL Glycoconjugate journal 36701102 Glycoconj J 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36701102
Who's in, who's out? Re-evaluation of lipid raft residents. Mlinac-Jerkovic K, Ilic K, Zjalić M, Mandić D, Debeljak Ž, Balog M, Damjanović V, Maček Hrvat N, Habek N, Kalanj-Bognar S, Schnaar RL, Heffer M Journal of neurochemistry 34081780 J Neurochem 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34081780
The Human Ganglioside Interactome in Live Cells Revealed Using Clickable Photoaffinity Ganglioside Probes. Zhang GL, Porter MJ, Awol AK, Orsburn BC, Canner SW, Gray JJ, O'Meally RN, Cole RN, Schnaar RL Journal of the American Chemical Society 38887845 J Am Chem Soc 2024 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/38887845
Tumor necrosis factor α receptor 1A transduces the inhibitory effect on axon regeneration triggered by IgG anti-ganglioside GD1a antibodies. Báez BB, Bacaglio CR, Prendergast JM, Rozés-Salvador V, Sheikh KA, Bianchet M, Farah MH, Schnaar RL, Bisbal M, Lopez PHH Biochimica et biophysica acta. Molecular basis of disease 38897255 Biochim Biophys Acta Mol Basis Dis 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/38897255
Designing Smaller, Synthetic, Functional Mimetics of Sulfated Glycosaminoglycans as Allosteric Modulators of Coagulation Factors. Abdelfadiel EI, Gunta R, Villuri BK, Afosah DK, Sankaranarayanan NV, Desai UR Journal of medicinal chemistry 37001055 J Med Chem 2023 Apr 13 https://www.ncbi.nlm.nih.gov/pubmed/37001055
Combinatorial Virtual Library Screening Study of Transforming Growth Factor-β2-Chondroitin Sulfate System. Sankaranarayanan NV, Nagarajan B, Desai UR International journal of molecular sciences 34299163 Int J Mol Sci 2021 Jul 14 https://www.ncbi.nlm.nih.gov/pubmed/34299163
Molecular dynamics simulations to understand glycosaminoglycan interactions in the free- and protein-bound states. Nagarajan B, Holmes SG, Sankaranarayanan NV, Desai UR Current opinion in structural biology 35306321 Curr Opin Struct Biol 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35306321
Assessing Genetic Algorithm-Based Docking Protocols for Prediction of Heparin Oligosaccharide Binding Geometries onto Proteins. Holmes SG, Desai UR Biomolecules 38002315 Biomolecules 2023 Nov 9 https://www.ncbi.nlm.nih.gov/pubmed/38002315
Alteration of Neuropilin-1 and Heparan Sulfate Interaction Impairs Murine B16 Tumor Growth. Painter CD, Sankaranarayanan NV, Nagarajan B, Mandel Clausen T, West AMV, Setiawan NJ, Park J, Porell RN, Bartels PL, Sandoval DR, Vasquez GJ, Chute JP, Godula K, Vander Kooi CW, Gordts PLSM, Corbett KD, Termini CM, Desai UR, Esko JD ACS chemical biology 39099090 ACS Chem Biol 2024 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/39099090
Discovering small-molecule therapeutics against SARS-CoV-2. Tiwari V, Beer JC, Sankaranarayanan NV, Swanson-Mungerson M, Desai UR Drug discovery today 32574699 Drug Discov Today 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32574699
Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3-O-sulfated heparan sulfate. Tiwari V, Tandon R, Sankaranarayanan NV, Beer JC, Kohlmeir EK, Swanson-Mungerson M, Desai UR bioRxiv : the preprint server for biology 33052337 bioRxiv 2020 Oct 8 https://www.ncbi.nlm.nih.gov/pubmed/33052337
Structural Insights Into How Proteoglycans Determine Chemokine-CXCR1/CXCR2 Interactions: Progress and Challenges. Rajarathnam K, Desai UR Frontiers in immunology 32391006 Front Immunol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32391006
Merging cultures and disciplines to create a drug discovery ecosystem at Virginia commonwealth university: Medicinal chemistry, structural biology, molecular and behavioral pharmacology and computational chemistry. Kellogg GE, Cen Y, Dukat M, Ellis KC, Guo Y, Li J, May AE, Safo MK, Zhang S, Zhang Y, Desai UR SLAS discovery : advancing life sciences R & D 36863508 SLAS Discov 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/36863508
Computational studies on glycosaminoglycan recognition of sialyl transferases. Sankaranarayanan NV, Sistla S, Nagarajan B, Chittum JE, Lau JTY, Desai UR Glycobiology 37171590 Glycobiology 2023 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/37171590
In-Depth Molecular Dynamics Study of All Possible Chondroitin Sulfate Disaccharides Reveals Key Insight into Structural Heterogeneity and Dynamism. Nagarajan B, Sankaranarayanan NV, Desai UR Biomolecules 35053225 Biomolecules 2022 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/35053225
A Robust Proteomics-Based Method for Identifying Preferred Protein Targets of Synthetic Glycosaminoglycan Mimetics. Afosah DK, Ongolu R, Fayyad RM, Hawkridge A, Desai UR bioRxiv : the preprint server for biology 39896571 bioRxiv 2025 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/39896571
The alphaherpesvirus conserved pUS10 is important for natural infection and its expression is regulated by the conserved Herpesviridae protein kinase (CHPK). Ponnuraj N, Akbar H, Arrington JV, Spatz SJ, Nagarajan B, Desai UR, Jarosinski KW PLoS pathogens 36749787 PLoS Pathog 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/36749787
On the Selectivity of Heparan Sulfate Recognition by SARS-CoV-2 Spike Glycoprotein. Chittum JE, Sankaranarayanan NV, O'Hara CP, Desai UR ACS medicinal chemistry letters 34786180 ACS Med Chem Lett 2021 Nov 11 https://www.ncbi.nlm.nih.gov/pubmed/34786180
Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8. Morla S, Desai UR Biomolecules 32784891 Biomolecules 2020 Aug 9 https://www.ncbi.nlm.nih.gov/pubmed/32784891
Design and Synthesis of Small Molecule Probes of MDA-9/Syntenin. Sankaranarayanan NV, Villuri BK, Nagarajan B, Lewicki S, Das SK, Fisher PB, Desai UR Biomolecules 39456220 Biomolecules 2024 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/39456220
Novel Isobaric Tagging Reagent Enabled Multiplex Quantitative Glycoproteomics via Electron-Transfer/Higher-Energy Collisional Dissociation (EThcD) Mass Spectrometry. Li M, Zhong X, Feng Y, Li L Journal of the American Society for Mass Spectrometry 36095095 J Am Soc Mass Spectrom 2022 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/36095095
Quantitative Analysis and Structural Elucidation of Fatty Acids by Isobaric Multiplex Labeling Reagents for Carbonyl-Containing Compound (SUGAR) Tags and m-CPBA Epoxidation. Feng Y, Lv Y, Gu TJ, Chen B, Li L Analytical chemistry 36099193 Anal Chem 2022 Sep 27 https://www.ncbi.nlm.nih.gov/pubmed/36099193
On-tissue amidation of sialic acid with aniline for sensitive imaging of sialylated N-glycans from FFPE tissue sections via MALDI mass spectrometry. Zhang H, Shi X, Liu Y, Wang B, Xu M, Welham NV, Li L Analytical and bioanalytical chemistry 35072748 Anal Bioanal Chem 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35072748
Signature-Ion-Triggered Mass Spectrometry Approach Enabled Discovery of N- and O-Linked Glycosylated Neuropeptides in the Crustacean Nervous System. Cao Q, Yu Q, Liu Y, Chen Z, Li L Journal of proteome research 31875397 J Proteome Res 2020 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/31875397
Discovery of Missing Methylation Sites on Endogenous Peptides of Human Cell Lines. Yan X, Li L, Jia C Journal of the American Society for Mass Spectrometry 31429054 J Am Soc Mass Spectrom 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31429054
Recent advances in mass spectrometry (MS)-based glycoproteomics in complex biological samples. Chen Z, Huang J, Li L Trends in analytical chemistry : TRAC 31579312 Trends Analyt Chem 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31579312
Isolation and characterization of glycosylated neuropeptides. Liu Y, Cao Q, Li L Methods in enzymology 31606074 Methods Enzymol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31606074
Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling. Li G, Ma F, Cao Q, Zheng Z, DeLaney K, Liu R, Li L Nature communications 31619683 Nat Commun 2019 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/31619683
Dual-Functional Ti(IV)-IMAC Material Enables Simultaneous Enrichment and Separation of Diverse Glycopeptides and Phosphopeptides. Huang J, Liu X, Wang D, Cui Y, Shi X, Dong J, Ye M, Li L Analytical chemistry 34100586 Anal Chem 2021 Jun 22 https://www.ncbi.nlm.nih.gov/pubmed/34100586
Recent Advances in Mass Spectrometry-Based Glycomic and Glycoproteomic Studies of Pancreatic Diseases. Tabang DN, Ford M, Li L Frontiers in chemistry 34368082 Front Chem 2021 https://www.ncbi.nlm.nih.gov/pubmed/34368082
In-Depth Site-Specific O-Glycosylation Analysis of Glycoproteins and Endogenous Peptides in Cerebrospinal Fluid (CSF) from Healthy Individuals, Mild Cognitive Impairment (MCI), and Alzheimer's Disease (AD) Patients. Chen Z, Wang D, Yu Q, Johnson J, Shipman R, Zhong X, Huang J, Yu Q, Zetterberg H, Asthana S, Carlsson C, Okonkwo O, Li L ACS chemical biology 34964596 ACS Chem Biol 2022 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/34964596
Cotton Ti-IMAC: Developing Phosphorylated Cotton as a Novel Platform for Phosphopeptide Enrichment. Wang D, Huang J, Zhang H, Gu TJ, Li L ACS applied materials & interfaces 37812448 ACS Appl Mater Interfaces 2023 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/37812448
Site-specific chirality-conferred structural compaction differentially mediates the cytotoxicity of Aβ42. Li G, Jeon CK, Ma M, Jia Y, Zheng Z, Delafield DG, Lu G, Romanova EV, Sweedler JV, Ruotolo BT, Li L Chemical science 37293657 Chem Sci 2023 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/37293657
Recent Advances in Analytical Approaches for Glycan and Glycopeptide Quantitation. Delafield DG, Li L Molecular & cellular proteomics : MCP 32576592 Mol Cell Proteomics 2021 https://www.ncbi.nlm.nih.gov/pubmed/32576592
Chemoenzymatic Synthesis of Glycopeptides Bearing Galactose-Xylose Disaccharide from the Proteoglycan Linkage Region. Gao J, Lin PH, Nick ST, Huang J, Tykesson E, Ellervik U, Li L, Huang X Organic letters 33576634 Org Lett 2021 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/33576634
Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity. Dos Santos Dias L, Dobson HE, Bakke BK, Kujoth GC, Huang J, Kohn EM, Taira CL, Wang H, Supekar NT, Fites JS, Gates D, Gomez CL, Specht CA, Levitz SM, Azadi P, Li L, Suresh M, Klein BS, Wüthrich M PLoS pathogens 33735218 PLoS Pathog 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33735218
High-resolution magnetic resonance and mass spectrometry imaging of the human larynx. Kishimoto AO, Kishimoto Y, Shi X, Hutchinson EB, Zhang H, Shi Y, Oliveira G, Li L, Welham NV, Rowland IJ Journal of anatomy 34032275 J Anat 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34032275
Developing mass spectrometry for the quantitative analysis of neuropeptides. Sauer CS, Phetsanthad A, Riusech OL, Li L Expert review of proteomics 34375152 Expert Rev Proteomics 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34375152
In-depth Site-specific Analysis of N-glycoproteome in Human Cerebrospinal Fluid and Glycosylation Landscape Changes in Alzheimer's Disease. Chen Z, Yu Q, Yu Q, Johnson J, Shipman R, Zhong X, Huang J, Asthana S, Carlsson C, Okonkwo O, Li L Molecular & cellular proteomics : MCP 33862227 Mol Cell Proteomics 2021 https://www.ncbi.nlm.nih.gov/pubmed/33862227
The transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium. Chan NT, Huang J, Ma G, Zeng H, Donahue K, Wang Y, Li L, Xu W Nucleic acids research 35137163 Nucleic Acids Res 2022 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/35137163
Quantification and molecular imaging of fatty acid isomers from complex biological samples by mass spectrometry. Zhang H, Xu M, Shi X, Liu Y, Li Z, Jagodinsky JC, Ma M, Welham NV, Morris ZS, Li L Chemical science 34194701 Chem Sci 2021 May 4 https://www.ncbi.nlm.nih.gov/pubmed/34194701
Enabling Global Analysis of Protein Citrullination via Biotin Thiol Tag-Assisted Mass Spectrometry. Shi Y, Li Z, Wang B, Shi X, Ye H, Delafield DG, Lv L, Ye Z, Chen Z, Ma F, Li L Analytical chemistry 36512406 Anal Chem 2022 Dec 27 https://www.ncbi.nlm.nih.gov/pubmed/36512406
Finding the Sweet Spot in ERLIC Mobile Phase for Simultaneous Enrichment of N-Glyco and Phosphopeptides. Cui Y, Yang K, Tabang DN, Huang J, Tang W, Li L Journal of the American Society for Mass Spectrometry 31286442 J Am Soc Mass Spectrom 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31286442
Dual-Functional Titanium(IV) Immobilized Metal Affinity Chromatography Approach for Enabling Large-Scale Profiling of Protein Mannose-6-Phosphate Glycosylation and Revealing Its Predominant Substrates. Huang J, Dong J, Shi X, Chen Z, Cui Y, Liu X, Ye M, Li L Analytical chemistry 31398006 Anal Chem 2019 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/31398006
Mass Spectrometry Imaging of N-Glycans from Formalin-Fixed Paraffin-Embedded Tissue Sections Using a Novel Subatmospheric Pressure Ionization Source. Shi Y, Li Z, Felder MA, Yu Q, Shi X, Peng Y, Cao Q, Wang B, Puglielli L, Patankar MS, Li L Analytical chemistry 31507162 Anal Chem 2019 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/31507162
Analysis of pancreatic extracellular matrix protein post-translational modifications via electrostatic repulsion-hydrophilic interaction chromatography coupled with mass spectrometry. Tabang DN, Cui Y, Tremmel DM, Ford M, Li Z, Sackett SD, Odorico JS, Li L Molecular omics 34318855 Mol Omics 2021 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/34318855
Evaluation of Collagen Alterations in Early Precursor Lesions of High Grade Serous Ovarian Cancer by Second Harmonic Generation Microscopy and Mass Spectrometry. Gant KL, Jambor AN, Li Z, Rentchler EC, Weisman P, Li L, Patankar MS, Campagnola PJ Cancers 34199725 Cancers (Basel) 2021 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/34199725
Counterion Optimization Dramatically Improves Selectivity for Phosphopeptides and Glycopeptides in Electrostatic Repulsion-Hydrophilic Interaction Chromatography. Cui Y, Tabang DN, Zhang Z, Ma M, Alpert AJ, Li L Analytical chemistry 34042420 Anal Chem 2021 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/34042420
DiLeuPMP: A Multiplexed Isobaric Labeling Method for Quantitative Analysis of O-Glycans. Li M, Gu TJ, Lin X, Li L Analytical chemistry 34240851 Anal Chem 2021 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/34240851
Simultaneous enrichment and separation of neutral and sialyl glycopeptides of SARS-CoV-2 spike protein enabled by dual-functionalized Ti-IMAC material. Huang J, Wang D, Shipman RD, Zhu Z, Liu Y, Li L Analytical and bioanalytical chemistry 34155551 Anal Bioanal Chem 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34155551
Selective Enrichment of Sialylglycopeptides Enabled by Click Chemistry and Dynamic Covalent Exchange. Li M, Huang J, Ma M, Shi X, Li L Analytical chemistry 35467842 Anal Chem 2022 May 10 https://www.ncbi.nlm.nih.gov/pubmed/35467842
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High density fermentation of probiotic E. coli Nissle 1917 towards heparosan production, characterization, and modification. Datta P, Fu L, Brodfuerer P, Dordick JS, Linhardt RJ Applied microbiology and biotechnology 33481068 Appl Microbiol Biotechnol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33481068
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Glycosaminoglycan Compositional Analysis of Relevant Tissues in Zika Virus Pathogenesis and in Vitro Evaluation of Heparin as an Antiviral against Zika Virus Infection. Kim SY, Koetzner CA, Payne AF, Nierode GJ, Yu Y, Wang R, Barr E, Dordick JS, Kramer LD, Zhang F, Linhardt RJ Biochemistry 30698412 Biochemistry 2019 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/30698412
Synthetic heparan sulfate standards and machine learning facilitate the development of solid-state nanopore analysis. Xia K, Hagan JT, Fu L, Sheetz BS, Bhattacharya S, Zhang F, Dwyer JR, Linhardt RJ Proceedings of the National Academy of Sciences of the United States of America 33688052 Proc Natl Acad Sci U S A 2021 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/33688052
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Heparosan Chain Characterization: Sequential Depolymerization of E. Coli K5 Heparosan by a Bacterial Eliminase Heparin Lyase III and a Bacterial Hydrolase Heparanase Bp to Prepare Defined Oligomers. Datta P, Yan L, Awofiranye A, Dordick JS, Linhardt RJ Biotechnology journal 33006278 Biotechnol J 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33006278
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Analysis of the Glycosaminoglycan Chains of Proteoglycans. Song Y, Zhang F, Linhardt RJ The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 32623943 J Histochem Cytochem 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/32623943
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High-throughput method for in process monitoring of 3-O-sulfotransferase catalyzed sulfonation in bioengineered heparin synthesis. Lin L, Yu Y, Zhang F, Zhang X, Linhardt RJ Analytical biochemistry 31518551 Anal Biochem 2019 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/31518551
Comparison of the Interactions of Different Growth Factors and Glycosaminoglycans. Zhang F, Zheng L, Cheng S, Peng Y, Fu L, Zhang X, Linhardt RJ Molecules (Basel, Switzerland) 31527407 Molecules 2019 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/31527407
Bottom-up and top-down profiling of pentosan polysulfate. Lin L , Yu Y , Zhang F , Xia K , Zhang X , Linhardt RJ The Analyst 31287456 Analyst 2019 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/31287456
Structural characterization of a clinically described heparin-like substance in plasma causing bleeding. Yu Y, Bruzdoski K, Kostousov V, Hensch L, Hui SK, Siddiqui F, Farooqui A, Kouta A, Zhang F, Fareed J, Teruya J, Linhardt RJ Carbohydrate polymers 32536393 Carbohydr Polym 2020 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/32536393
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Structural Features of Heparin and Its Interactions With Cellular Prion Protein Measured by Surface Plasmon Resonance. Kim SY, Zhang F, Harris DA, Linhardt RJ Frontiers in molecular biosciences 33324681 Front Mol Biosci 2020 https://www.ncbi.nlm.nih.gov/pubmed/33324681
Unique Cell Surface Mannan of Yeast Pathogen Candida auris with Selective Binding to IgG. Yan L, Xia K, Yu Y, Miliakos A, Chaturvedi S, Zhang F, Chen S, Chaturvedi V, Linhardt RJ ACS infectious diseases 32233507 ACS Infect Dis 2020 May 8 https://www.ncbi.nlm.nih.gov/pubmed/32233507
Elucidating the unusual reaction kinetics of D-glucuronyl C5-epimerase. Vaidyanathan D, Paskaleva E, Vargason T, Ke X, McCallum SA, Linhardt RJ, Dordick JS Glycobiology 32304324 Glycobiology 2020 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/32304324
Expression of enzymes for 3'-phosphoadenosine-5'-phosphosulfate (PAPS) biosynthesis and their preparation for PAPS synthesis and regeneration. Datta P, Fu L, He W, Koffas MAG, Dordick JS, Linhardt RJ Applied microbiology and biotechnology 32601738 Appl Microbiol Biotechnol 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32601738
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A multiplexed microflow LC-MS/MS-PRM assay for serologic quantification of IgG N- and HPX O- glycoforms in liver fibrosis. Panigrahi A, Zhang L, Benicky J, Sanda M, Ahn J, Goldman R Scientific reports 36635317 Sci Rep 2023 Jan 12 https://www.ncbi.nlm.nih.gov/pubmed/36635317
Quantitative Analysis of Sex-Hormone-Binding Globulin Glycosylation in Liver Diseases by Liquid Chromatography-Mass Spectrometry Parallel Reaction Monitoring. Yuan W, Benicky J, Wei R, Goldman R, Sanda M Journal of proteome research 29972295 J Proteome Res 2018 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/29972295
Glycan-specific precipitation of glycopeptides in high organic content sample solvents used in HILIC. Kozlik P, Molnarova K, Jecmen T, Krizek T, Goldman R Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 32485649 J Chromatogr B Analyt Technol Biomed Life Sci 2020 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/32485649
"Ghost" Fragment Ions in Structure and Site-Specific Glycoproteomics Analysis. Campos D, Girgis M, Yang Q, Zong G, Goldman R, Wang LX, Sanda M Analytical chemistry 37382290 Anal Chem 2023 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/37382290
Low Collision Energy Fragmentation in Structure-Specific Glycoproteomics Analysis. Sanda M, Benicky J, Goldman R Analytical chemistry 32441515 Anal Chem 2020 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/32441515
Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Kawahara R, Chernykh A, Alagesan K, Bern M, Cao W, Chalkley RJ, Cheng K, Choo MS, Edwards N, Goldman R, Hoffmann M, Hu Y, Huang Y, Kim JY, Kletter D, Liquet B, Liu M, Mechref Y, Meng B, Neelamegham S, Nguyen-Khuong T, Nilsson J, Pap A, Park GW, Parker BL, Pegg CL, Penninger JM, Phung TK, Pioch M, Rapp E, Sakalli E, Sanda M, Schulz BL, Scott NE, Sofronov G, Stadlmann J, Vakhrushev SY, Woo CM, Wu HY, Yang P, Ying W, Zhang H, Zhang Y, Zhao J, Zaia J, Haslam SM, Palmisano G, Yoo JS, Larson G, Khoo KH, Medzihradszky KF, Kolarich D, Packer NH, Thaysen-Andersen M Nature methods 34725484 Nat Methods 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34725484
LC-MS/MS-PRM Quantification of IgG Glycoforms Using Stable Isotope Labeled IgG1 Fc Glycopeptide Standard. Sanda M, Yang Q, Zong G, Chen H, Zheng Z, Dhani H, Khan K, Kroemer A, Wang LX, Goldman R Journal of proteome research 36763792 J Proteome Res 2023 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/36763792
Analysis of site and structure specific core fucosylation in liver cirrhosis using exoglycosidase-assisted data-independent LC-MS/MS. Sanda M, Ahn J, Kozlik P, Goldman R Scientific reports 34857845 Sci Rep 2021 Dec 2 https://www.ncbi.nlm.nih.gov/pubmed/34857845
Heparan-6-O-Endosulfatase 2 Promotes Invasiveness of Head and Neck Squamous Carcinoma Cell Lines in Co-Cultures with Cancer-Associated Fibroblasts. Mukherjee P, Zhou X, Benicky J, Panigrahi A, Aljuhani R, Liu J, Ailles L, Pomin VH, Wang Z, Goldman R Cancers 37958342 Cancers (Basel) 2023 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/37958342
Optimized Fragmentation for Quantitative Analysis of Fucosylated N-Glycoproteins by LC-MS-MRM. Yuan W, Wei R, Goldman R, Sanda M Analytical chemistry 31268672 Anal Chem 2019 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/31268672
Glycoforms of human prostate-specific membrane antigen (PSMA) in human cells and prostate tissue. Yuan W, Liu B, Sanda M, Wei R, Benicky J, Novakova Z, Barinka C, Goldman R The Prostate 34662441 Prostate 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34662441
Quantitative analysis of core fucosylation of serum proteins in liver diseases by LC-MS-MRM. Ma J, Sanda M, Wei R, Zhang L, Goldman R Journal of proteomics 29427759 J Proteomics 2018 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/29427759
N- and O-Glycosylation of the SARS-CoV-2 Spike Protein. Sanda M, Morrison L, Goldman R Analytical chemistry 33406838 Anal Chem 2021 Feb 2 https://www.ncbi.nlm.nih.gov/pubmed/33406838
Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines. Hintze J, Ye Z, Narimatsu Y, Madsen TD, Joshi HJ, Goth CK, Linstedt A, Bachert C, Mandel U, Bennett EP, Vakhrushev SY, Schjoldager KT The Journal of biological chemistry 30327431 J Biol Chem 2018 Dec 7 https://www.ncbi.nlm.nih.gov/pubmed/30327431
Site-specific glycosylation of Ebola virus glycoprotein by human polypeptide GalNAc-transferase 1 induces cell adhesion defects. Simon EJ, Linstedt AD The Journal of biological chemistry 30389789 J Biol Chem 2018 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/30389789
Archaic Hominin Introgression in Africa Contributes to Functional Salivary MUC7 Genetic Variation. Xu D, Pavlidis P, Taskent RO, Alachiotis N, Flanagan C, DeGiorgio M, Blekhman R, Ruhl S, Gokcumen O Molecular biology and evolution 28957509 Mol Biol Evol 2017 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/28957509
Independent amylase gene copy number bursts correlate with dietary preferences in mammals. Pajic P, Pavlidis P, Dean K, Neznanova L, Romano RA, Garneau D, Daugherity E, Globig A, Ruhl S, Gokcumen O eLife 31084707 Elife 2019 May 14 https://www.ncbi.nlm.nih.gov/pubmed/31084707
Modified Sialic Acids on Mucus and Erythrocytes Inhibit Influenza A Virus Hemagglutinin and Neuraminidase Functions. Barnard KN, Alford-Lawrence BK, Buchholz DW, Wasik BR, LaClair JR, Yu H, Honce R, Ruhl S, Pajic P, Daugherity EK, Chen X, Schultz-Cherry SL, Aguilar HC, Varki A, Parrish CR Journal of virology 32051275 J Virol 2020 Apr 16 https://www.ncbi.nlm.nih.gov/pubmed/32051275
Emergence of saliva protein genes in the secretory calcium-binding phosphoprotein (SCPP) locus and accelerated evolution in primates. Pajic P, Landau L, Gokcumen O, Ruhl S bioRxiv : the preprint server for biology 38405690 bioRxiv 2024 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/38405690
Streptococcal Siglec-like adhesins recognize different subsets of human plasma glycoproteins: implications for infective endocarditis. Bensing BA, Li Q, Park D, Lebrilla CB, Sullam PM Glycobiology 29796594 Glycobiology 2018 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/29796594
Human and Nonhuman Primate Lineage-Specific Footprints in the Salivary Proteome. Thamadilok S, Choi KS, Ruhl L, Schulte F, Kazim AL, Hardt M, Gokcumen O, Ruhl S Molecular biology and evolution 31614365 Mol Biol Evol 2020 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/31614365
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins. Malaker SA, Pedram K, Ferracane MJ, Bensing BA, Krishnan V, Pett C, Yu J, Woods EC, Kramer JR, Westerlind U, Dorigo O, Bertozzi CR Proceedings of the National Academy of Sciences of the United States of America 30910957 Proc Natl Acad Sci U S A 2019 Apr 9 https://www.ncbi.nlm.nih.gov/pubmed/30910957
A mechanism of gene evolution generating mucin function. Pajic P, Shen S, Qu J, May AJ, Knox S, Ruhl S, Gokcumen O Science advances 36026444 Sci Adv 2022 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/36026444
Glycan recognition at the saliva - oral microbiome interface. Cross BW, Ruhl S Cellular immunology 30274839 Cell Immunol 2018 Nov https://www.ncbi.nlm.nih.gov/pubmed/30274839
Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Bensing BA, Stubbs HE, Agarwal R, Yamakawa I, Luong K, Solakyildirim K, Yu H, Hadadianpour A, Castro MA, Fialkowski KP, Morrison KM, Wawrzak Z, Chen X, Lebrilla CB, Baudry J, Smith JC, Sullam PM, Iverson TM Nature communications 35585145 Nat Commun 2022 May 18 https://www.ncbi.nlm.nih.gov/pubmed/35585145
Tandem sialoglycan-binding modules in a Streptococcus sanguinis serine-rich repeat adhesin create target dependent avidity effects. Stubbs HE, Bensing BA, Yamakawa I, Sharma P, Yu H, Chen X, Sullam PM, Iverson TM The Journal of biological chemistry 32820052 J Biol Chem 2020 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/32820052
Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins. Purohit S, Li T, Guan W, Song X, Song J, Tian Y, Li L, Sharma A, Dun B, Mysona D, Ghamande S, Rungruang B, Cummings RD, Wang PG, She JX Nature communications 29343722 Nat Commun 2018 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/29343722
Multiplex Glycan Bead Array (MGBA ) for High Throughput and High Content Analyses of Glycan-Binding Proteins Including Natural Anti-Glycan Antibodies. Purohit S, She JX Methods in molecular biology (Clifton, N.J.) 34972929 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/34972929
Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes. Tran PMH, Dong F, Kim E, Richardson KP, Tran LKH, Waugh K, Hopkins D, Cummings RD, Wang PG, Rewers MJ, She JX, Purohit S Nature communications 36316364 Nat Commun 2022 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/36316364
A Phase I Clinical Trial of Guadecitabine and Carboplatin in Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic, and Pharmacodynamic Analyses. Matei D, Ghamande S, Roman L, Alvarez Secord A, Nemunaitis J, Markham MJ, Nephew KP, Jueliger S, Oganesian A, Naim S, Su XY, Keer H, Azab M, Fleming GF Clinical cancer research : an official journal of the American Association for Cancer Research 29500276 Clin Cancer Res 2018 May 15 https://www.ncbi.nlm.nih.gov/pubmed/29500276
Clinical calculator predictive of chemotherapy benefit in stage 1A uterine papillary serous cancers. Mysona DP, Tran LKH, Tran PMH, Gehrig PA, Van Le L, Ghamande S, Rungruang BJ, Java J, Mann AK, Liao J, Kapp DS, Santos BD, She JX, Chan JK Gynecologic oncology 31796203 Gynecol Oncol 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31796203
Better survival is observed in cervical cancer patients positive for specific anti-glycan antibodies and receiving brachytherapy. Purohit S, Ferris DG, Alvarez M, Tran PMH, Tran LKH, Mysona DP, Hopkins D, Zhi W, Dun B, Wallbillich JJ, Cummings RD, Wang PG, She JX Gynecologic oncology 31955861 Gynecol Oncol 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/31955861
Pleiotrophin interacts with glycosaminoglycans in a highly flexible and adaptable manner. Ryan E, Shen D, Wang X FEBS letters 33529353 FEBS Lett 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33529353
Glycosaminoglycan-Protein Interactions by Nuclear Magnetic Resonance (NMR) Spectroscopy. Pomin VH, Wang X Molecules (Basel, Switzerland) 30208595 Molecules 2018 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/30208595
Synthetic Oligosaccharide Libraries and Microarray Technology: A Powerful Combination for the Success of Current Glycosaminoglycan Interactomics. Pomin VH, Wang X ChemMedChem 29160016 ChemMedChem 2018 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/29160016
Deep Sequencing of Complex Proteoglycans: A Novel Strategy for High Coverage and Site-specific Identification of Glycosaminoglycan-linked Peptides. Klein JA, Meng L, Zaia J Molecular & cellular proteomics : MCP 29773674 Mol Cell Proteomics 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29773674
Software for Peak Finding and Elemental Composition Assignment for Glycosaminoglycan Tandem Mass Spectra. Hogan JD, Klein JA, Wu J, Chopra P, Boons GJ, Carvalho L, Lin C, Zaia J Molecular & cellular proteomics : MCP 29615495 Mol Cell Proteomics 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29615495
psims - A Declarative Writer for mzML and mzIdentML for Python. Klein J, Zaia J Molecular & cellular proteomics : MCP 30563850 Mol Cell Proteomics 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30563850
Proteomics, Glycomics, and Glycoproteomics of Matrisome Molecules. Raghunathan R, Sethi MK, Klein JA, Zaia J Molecular & cellular proteomics : MCP 31471497 Mol Cell Proteomics 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31471497
On-slide tissue digestion for mass spectrometry based glycomic and proteomic profiling. Raghunathan R, Sethi MK, Zaia J MethodsX 31660297 MethodsX 2019 https://www.ncbi.nlm.nih.gov/pubmed/31660297
A Perspective on the Confident Comparison of Glycoprotein Site-Specific Glycosylation in Sample Cohorts. Klein JA, Zaia J Biochemistry 31833756 Biochemistry 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31833756
Glycomic and Proteomic Changes in Aging Brain Nigrostriatal Pathway. Raghunathan R, Polinski NK, Klein JA, Hogan JD, Shao C, Khatri K, Leon D, McComb ME, Manfredsson FP, Sortwell CE, Zaia J Molecular & cellular proteomics : MCP 29915149 Mol Cell Proteomics 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/29915149
Influence of saccharide modifications on heparin lyase III substrate specificities. Wu J, Chopra P, Boons GJ, Zaia J Glycobiology 33822051 Glycobiology 2022 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/33822051
Glycoproteomic Sample Processing, LC-MS, and Data Analysis Using GlycReSoft. Wang M, Shajahan A, Pepi LE, Azadi P, Zaia J Current protocols 33761173 Curr Protoc 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33761173
GAGrank: Software for Glycosaminoglycan Sequence Ranking Using a Bipartite Graph Model. Hogan JD, Wu J, Klein JA, Lin C, Carvalho L, Zaia J Molecular & cellular proteomics : MCP 33992776 Mol Cell Proteomics 2021 https://www.ncbi.nlm.nih.gov/pubmed/33992776
RAMZIS: a bioinformatic toolkit for rigorous assessment of the alterations to glycoprotein structure that occur during biological processes. Hackett WE, Chang D, Carvalho L, Zaia J bioRxiv : the preprint server for biology 37398011 bioRxiv 2023 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/37398011
Characterization and Quantification of Highly Sulfated Glycosaminoglycan Isomers by Gated-Trapped Ion Mobility Spectrometry Negative Electron Transfer Dissociation MS/MS. Wei J, Wu J, Tang Y, Ridgeway ME, Park MA, Costello CE, Zaia J, Lin C Analytical chemistry 30649866 Anal Chem 2019 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/30649866
N-glycosylation in Spodoptera frugiperda (Lepidoptera: Noctuidae) midgut membrane-bound glycoproteins. Fuzita FJ, Chandler KB, Haserick JR, Terra WR, Ferreira C, Costello CE Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 32553552 Comp Biochem Physiol B Biochem Mol Biol 2020 Aug-Sep https://www.ncbi.nlm.nih.gov/pubmed/32553552
Glycosylation of Serum Clusterin in Wild-Type Transthyretin-Associated (ATTRwt) Amyloidosis: A Study of Disease-Associated Compositional Features Using Mass Spectrometry Analyses. Torres-Arancivia CM, Chang D, Hackett WE, Zaia J, Connors LH Biochemistry 33141553 Biochemistry 2020 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/33141553
In-Depth Matrisome and Glycoproteomic Analysis of Human Brain Glioblastoma Versus Control Tissue. Sethi MK, Downs M, Shao C, Hackett WE, Phillips JJ, Zaia J Molecular & cellular proteomics : MCP 35202840 Mol Cell Proteomics 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35202840
Data-independent acquisition mass spectrometry for site-specific glycoproteomics characterization of SARS-CoV-2 spike protein. Chang D, Klein JA, Nalehua MR, Hackett WE, Zaia J Analytical and bioanalytical chemistry 34635934 Anal Bioanal Chem 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34635934
Characterization of Isomeric Glycans by Reversed Phase Liquid Chromatography-Electronic Excitation Dissociation Tandem Mass Spectrometry. Tang Y, Wei J, Costello CE, Lin C Journal of the American Society for Mass Spectrometry 29654534 J Am Soc Mass Spectrom 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29654534
Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus. van Eijk M, Rynkiewicz MJ, Khatri K, Leymarie N, Zaia J, White MR, Hartshorn KL, Cafarella TR, van Die I, Hessing M, Seaton BA, Haagsman HP The Journal of biological chemistry 29769321 J Biol Chem 2018 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/29769321
Improving Statistical Certainty of Glycosylation Similarity between Influenza A Virus Variants Using Data-Independent Acquisition Mass Spectrometry. Chang D, Klein J, Hackett WE, Nalehua MR, Wan XF, Zaia J Molecular & cellular proteomics : MCP 36103992 Mol Cell Proteomics 2022 Nov https://www.ncbi.nlm.nih.gov/pubmed/36103992
The 3-O-sulfation of heparan sulfate modulates protein binding and lyase degradation. Chopra P, Joshi A, Wu J, Lu W, Yadavalli T, Wolfert MA, Shukla D, Zaia J, Boons GJ Proceedings of the National Academy of Sciences of the United States of America 33441484 Proc Natl Acad Sci U S A 2021 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/33441484
Toward Automatic and Comprehensive Glycan Characterization by Online PGC-LC-EED MS/MS. Wei J, Tang Y, Bai Y, Zaia J, Costello CE, Hong P, Lin C Analytical chemistry 31829560 Anal Chem 2020 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/31829560
Serial in-solution digestion protocol for mass spectrometry-based glycomics and proteomics analysis. Sethi MK, Downs M, Zaia J Molecular omics 32309832 Mol Omics 2020 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/32309832
A glycomics and proteomics study of aging and Parkinson's disease in human brain. Raghunathan R, Hogan JD, Labadorf A, Myers RH, Zaia J Scientific reports 32733076 Sci Rep 2020 Jul 30 https://www.ncbi.nlm.nih.gov/pubmed/32733076
Negative Electron Transfer Dissociation Sequencing of 3-O-Sulfation-Containing Heparan Sulfate Oligosaccharides. Wu J, Wei J, Hogan JD, Chopra P, Joshi A, Lu W, Klein J, Boons GJ, Lin C, Zaia J Journal of the American Society for Mass Spectrometry 29564812 J Am Soc Mass Spectrom 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29564812
Sensitive method for glycosaminoglycan analysis of tissue sections. Turiák L, Tóth G, Ozohanics O, Révész Á, Ács A, Vékey K, Zaia J, Drahos L Journal of chromatography. A 29506752 J Chromatogr A 2018 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/29506752
Comprehensive Glycomic and Proteomic Analysis of Mouse Striatum and Lateral Hypothalamus Following Repeated Exposures to Cocaine or Methamphetamine. Sethi MK, Maccioni R, Hogan JD, Kawamura T, Repunte-Canonigo V, Chen J, Zaia J, Sanna PP Molecular & cellular proteomics : MCP 38880242 Mol Cell Proteomics 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38880242
Sequencing Heparan Sulfate Using HILIC LC-NETD-MS/MS. Wu J, Wei J, Chopra P, Boons GJ, Lin C, Zaia J Analytical chemistry 31423779 Anal Chem 2019 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/31423779
glypy: An Open Source Glycoinformatics Library. Klein J, Zaia J Journal of proteome research 31310539 J Proteome Res 2019 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/31310539
Why Glycosylation Matters in Building a Better Flu Vaccine. Chang D, Zaia J Molecular & cellular proteomics : MCP 31604803 Mol Cell Proteomics 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31604803
Resolving Heparan Sulfate Oligosaccharide Positional Isomers Using Hydrophilic Interaction Liquid Chromatography-Cyclic Ion Mobility Mass Spectrometry. Cavallero GJ, Zaia J Analytical chemistry 35090117 Anal Chem 2022 Feb 8 https://www.ncbi.nlm.nih.gov/pubmed/35090117
Application of network smoothing to glycan LC-MS profiling. Klein J, Carvalho L, Zaia J Bioinformatics (Oxford, England) 29790907 Bioinformatics 2018 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/29790907
Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues. Muraoka S, DeLeo AM, Sethi MK, Yukawa-Takamatsu K, Yang Z, Ko J, Hogan JD, Ruan Z, You Y, Wang Y, Medalla M, Ikezu S, Chen M, Xia W, Gorantla S, Gendelman HE, Issadore D, Zaia J, Ikezu T Alzheimer's & dementia : the journal of the Alzheimer's Association 32301581 Alzheimers Dement 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32301581
Measuring Site-specific Glycosylation Similarity between Influenza a Virus Variants with Statistical Certainty. Chang D, Hackett WE, Zhong L, Wan XF, Zaia J Molecular & cellular proteomics : MCP 32601173 Mol Cell Proteomics 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32601173
Calculating Glycoprotein Similarities From Mass Spectrometric Data. Hackett WE, Zaia J Molecular & cellular proteomics : MCP 32883803 Mol Cell Proteomics 2021 https://www.ncbi.nlm.nih.gov/pubmed/32883803
β-Catenin/CBP inhibition alters epidermal growth factor receptor fucosylation status in oral squamous cell carcinoma. Chandler KB, Alamoud KA, Stahl VL, Nguyen BC, Kartha VK, Bais MV, Nomoto K, Owa T, Monti S, Kukuruzinska MA, Costello CE Molecular omics 32203567 Mol Omics 2020 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/32203567
Relative Retention Time Estimation Improves N-Glycopeptide Identifications by LC-MS/MS. Klein J, Zaia J Journal of proteome research 32223173 J Proteome Res 2020 May 1 https://www.ncbi.nlm.nih.gov/pubmed/32223173
Synthesis of Functionalized N-Acetyl Muramic Acids To Probe Bacterial Cell Wall Recycling and Biosynthesis. DeMeester KE, Liang H, Jensen MR, Jones ZS, D'Ambrosio EA, Scinto SL, Zhou J, Grimes CL Journal of the American Chemical Society 29986130 J Am Chem Soc 2018 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/29986130
Investigating Peptidoglycan Recycling Pathways in Tannerella forsythia with N-Acetylmuramic Acid Bioorthogonal Probes. Wodzanowski KA, Hyland SN, Chinthamani S, Sandles LD, Honma K, Sharma A, Grimes CL ACS infectious diseases 35924866 ACS Infect Dis 2022 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/35924866
Cell morphology as a virulence determinant: lessons from Helicobacter pylori. Salama NR Current opinion in microbiology 32014717 Curr Opin Microbiol 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32014717
Membrane-partitioned cell wall synthesis in mycobacteria. García-Heredia A, Kado T, Sein CE, Puffal J, Osman SH, Judd J, Gray TA, Morita YS, Siegrist MS eLife 33544079 Elife 2021 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/33544079
Tools for probing host-bacteria interactions in the gut microenvironment: From molecular to cellular levels. Wodzanowski KA, Cassel SE, Grimes CL, Kloxin AM Bioorganic & medicinal chemistry letters 32223923 Bioorg Med Chem Lett 2020 May 15 https://www.ncbi.nlm.nih.gov/pubmed/32223923
Metabolic Incorporation of N-Acetyl Muramic Acid Probes into Bacterial Peptidoglycan. DeMeester KE, Liang H, Zhou J, Wodzanowski KA, Prather BL, Santiago CC, Grimes CL Current protocols in chemical biology 31763799 Curr Protoc Chem Biol 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31763799
Protected N-Acetyl Muramic Acid Probes Improve Bacterial Peptidoglycan Incorporation via Metabolic Labeling. Brown AR, Wodzanowski KA, Santiago CC, Hyland SN, Follmar JL, Asare-Okai P, Grimes CL ACS chemical biology 34506714 ACS Chem Biol 2021 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/34506714
Chemical Biology Tools for Examining the Bacterial Cell Wall. Brown AR, Gordon RA, Hyland SN, Siegrist MS, Grimes CL Cell chemical biology 32822617 Cell Chem Biol 2020 Aug 20 https://www.ncbi.nlm.nih.gov/pubmed/32822617
A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW. Yang X, McQuillen R, Lyu Z, Phillips-Mason P, De La Cruz A, McCausland JW, Liang H, DeMeester KE, Santiago CC, Grimes CL, de Boer P, Xiao J Nature microbiology 33495624 Nat Microbiol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33495624
Utility of bacterial peptidoglycan recycling enzymes in the chemoenzymatic synthesis of valuable UDP sugar substrates. Ukaegbu OI, DeMeester KE, Liang H, Brown AR, Jones ZS, Grimes CL Methods in enzymology 32416908 Methods Enzymol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32416908
DivIVA concentrates mycobacterial cell envelope assembly for initiation and stabilization of polar growth. Melzer ES, Sein CE, Chambers JJ, Siegrist MS Cytoskeleton (Hoboken, N.J.) 30160378 Cytoskeleton (Hoboken) 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30160378
Coupling Novel Probes with Molecular Localization Microscopy Reveals Cell Wall Homeostatic Mechanisms in Staphylococcus aureus. Lund VA, Gangotra H, Zhao Z, Sutton JAF, Wacnik K, DeMeester K, Liang H, Santiago C, Leimkuhler Grimes C, Jones S, Foster SJ ACS chemical biology 36414253 ACS Chem Biol 2022 Dec 16 https://www.ncbi.nlm.nih.gov/pubmed/36414253
Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori. Taylor JA, Bratton BP, Sichel SR, Blair KM, Jacobs HM, DeMeester KE, Kuru E, Gray J, Biboy J, VanNieuwenhze MS, Vollmer W, Grimes CL, Shaevitz JW, Salama NR eLife 31916938 Elife 2020 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/31916938
Peptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria. García-Heredia A, Pohane AA, Melzer ES, Carr CR, Fiolek TJ, Rundell SR, Lim HC, Wagner JC, Morita YS, Swarts BM, Siegrist MS eLife 30198841 Elife 2018 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/30198841
Localizing Peptidoglycan Synthesis in Helicobacter pylori using Clickable Metabolic Probes. Taylor JA, Santiago CC, Gray J, Wodzanowski KA, DeMeester KE, Biboy J, Vollmer W, Grimes CL, Salama NR Current protocols 33844460 Curr Protoc 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33844460
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Sweet Control: MicroRNA Regulation of the Glycome. Thu CT, Mahal LK Biochemistry 31585501 Biochemistry 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31585501
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Comprehensive Analytical Approach toward Glycomic Characterization and Profiling in Urinary Exosomes. Zou G, Benktander JD, Gizaw ST, Gaunitz S, Novotny MV Analytical chemistry 28402650 Anal Chem 2017 May 16 https://www.ncbi.nlm.nih.gov/pubmed/28402650
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Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction. Robinson PV, Tsai CT, de Groot AE, McKechnie JL, Bertozzi CR Journal of the American Chemical Society 27454154 J Am Chem Soc 2016 Aug 31 https://www.ncbi.nlm.nih.gov/pubmed/27454154
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Ultrasensitive quantification of tumor mRNAs in extracellular vesicles with an integrated microfluidic digital analysis chip. Zhang P, Crow J, Lella D, Zhou X, Samuel G, Godwin AK, Zeng Y Lab on a chip 30474100 Lab Chip 2018 Dec 4 https://www.ncbi.nlm.nih.gov/pubmed/30474100
Multiplexed immunophenotyping of circulating exosomes on nano-engineered ExoProfile chip towards early diagnosis of cancer. Zhang P, Zhou X, Zeng Y Chemical science 31293733 Chem Sci 2019 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/31293733
In Situ Imaging of Tryptic Peptides by MALDI Imaging Mass Spectrometry Using Fresh-Frozen or Formalin-Fixed, Paraffin-Embedded Tissue. Angel PM, Norris-Caneda K, Drake RR Current protocols in protein science 30114342 Curr Protoc Protein Sci 2018 Nov https://www.ncbi.nlm.nih.gov/pubmed/30114342
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The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. Barnett D, Liu Y, Partyka K, Huang Y, Tang H, Hostetter G, Brand RE, Singhi AD, Drake RR, Haab BB Scientific reports 28642461 Sci Rep 2017 Jun 22 https://www.ncbi.nlm.nih.gov/pubmed/28642461
Mapping Extracellular Matrix Proteins in Formalin-Fixed, Paraffin-Embedded Tissues by MALDI Imaging Mass Spectrometry. Angel PM, Comte-Walters S, Ball LE, Talbot K, Mehta A, Brockbank KGM, Drake RR Journal of proteome research 29161047 J Proteome Res 2018 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/29161047
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A Microfluidic Dual-Aptamer Sandwich Assay for Rapid and Cost-Effective Detection of Recombinant Proteins. Wen K, Chen Y, Meng X, Botros S, Dai W, Stojanovic MN, Tomer R, Lin Q Microchemical journal : devoted to the application of microtechniques in all branches of science 36992861 Microchem J 2023 May https://www.ncbi.nlm.nih.gov/pubmed/36992861
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Capillary Electrophoresis-Nanoelectrospray Ionization-Selected Reaction Monitoring Mass Spectrometry via a True Sheathless Metal-Coated Emitter Interface for Robust and High-Sensitivity Sample Quantification. Guo X, Fillmore TL, Gao Y, Tang K Analytical chemistry 27028594 Anal Chem 2016 Apr 19 https://www.ncbi.nlm.nih.gov/pubmed/27028594
Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations. Nagy G , Attah IK , Garimella SVB , Tang K , Ibrahim YM , Baker ES , Smith RD Chemical communications (Cambridge, England) 30264832 Chem Commun (Camb) 2018 Oct 25 https://www.ncbi.nlm.nih.gov/pubmed/30264832
Enhancing glycan isomer separations with metal ions and positive and negative polarity ion mobility spectrometry-mass spectrometry analyses. Zheng X, Zhang X, Schocker NS, Renslow RS, Orton DJ, Khamsi J, Ashmus RA, Almeida IC, Tang K, Costello CE, Smith RD, Michael K, Baker ES Analytical and bioanalytical chemistry 27604268 Anal Bioanal Chem 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27604268
Glycocalyx Scaffolding to Control Cell Surface Glycan Displays. Huang ML, Tota EM, Verespy S 3rd, Godula K Current protocols in chemical biology 29927116 Curr Protoc Chem Biol 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29927116
Glycocalyx crowding with mucin mimetics strengthens binding of soluble and virus-associated lectins to host cell glycan receptors. Honigfort DJ, Altman MO, Gagneux P, Godula K Proceedings of the National Academy of Sciences of the United States of America 34583992 Proc Natl Acad Sci U S A 2021 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/34583992
Mucin-mimetic glycan arrays integrating machine learning for analyzing receptor pattern recognition by influenza A viruses. Lucas TM, Gupta C, Altman MO, Sanchez E, Naticchia MR, Gagneux P, Singharoy A, Godula K Chem 34993358 Chem 2021 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/34993358
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Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries. Honigfort DJ, Zhang MH, Verespy S, Godula K Faraday discussions 31313786 Faraday Discuss 2019 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/31313786
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GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility. Reynoso S, Castillo V, Katkar GD, Lopez-Sanchez I, Taheri S, Espinoza C, Rohena C, Sahoo D, Gagneux P, Ghosh P eLife 34409938 Elife 2021 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/34409938
Global mapping of glycosylation pathways in human-derived cells. Huang YF, Aoki K, Akase S, Ishihara M, Liu YS, Yang G, Kizuka Y, Mizumoto S, Tiemeyer M, Gao XD, Aoki-Kinoshita KF, Fujita M Developmental cell 33730547 Dev Cell 2021 Apr 19 https://www.ncbi.nlm.nih.gov/pubmed/33730547
A Recurrent De Novo Heterozygous COG4 Substitution Leads to Saul-Wilson Syndrome, Disrupted Vesicular Trafficking, and Altered Proteoglycan Glycosylation. Ferreira CR, Xia ZJ, Clément A, Parry DA, Davids M, Taylan F, Sharma P, Turgeon CT, Blanco-Sánchez B, Ng BG, Logan CV, Wolfe LA, Solomon BD, Cho MT, Douglas G, Carvalho DR, Bratke H, Haug MG, Phillips JB, Wegner J, Tiemeyer M, Aoki K, Undiagnosed Diseases Network, Scottish Genome Partnership, Nordgren A, Hammarsjö A, Duker AL, Rohena L, Hove HB, Ek J, Adams D, Tifft CJ, Onyekweli T, Weixel T, Macnamara E, Radtke K, Powis Z, Earl D, Gabriel M, Russi AHS, Brick L, Kozenko M, Tham E, Raymond KM, Phillips JA 3rd, Tiller GE, Wilson WG, Hamid R, Malicdan MCV, Nishimura G, Grigelioniene G, Jackson A, Westerfield M, Bober MB, Gahl WA, Freeze HH American journal of human genetics 30290151 Am J Hum Genet 2018 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/30290151
Glucuronylated core 1 glycans are required for precise localization of neuromuscular junctions and normal formation of basement membranes on Drosophila muscles. Itoh K, Akimoto Y, Kondo S, Ichimiya T, Aoki K, Tiemeyer M, Nishihara S Developmental biology 29499182 Dev Biol 2018 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/29499182
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