Skip to main content

Archived Content

Please note this webpage is being maintained as an archive and will not be updated on a regular basis.

close

Get Program Updates
Email
Twitter

Program Publications

Publications Search by Program

Search Results

The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Author Journal Name PubMedID Journal Abbreviation Publication Date PubMedLink
OFox imidates as versatile glycosyl donors for chemical glycosylation. Nigudkar SS, Wang T, Pistorio SG, Yasomanee JP, Stine KJ, Demchenko AV Organic & biomolecular chemistry 27808325 Org Biomol Chem 2017 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/27808325
Investigation of the H-bond-mediated aglycone delivery reaction in application to the synthesis of β-glucosides. Mannino MP, Yasomanee JP, Demchenko AV Carbohydrate research 30286335 Carbohydr Res 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30286335
Extending the S-benzimidazolyl (SBiz) platform: N-alkylated SBiz glycosyl donors with the universal activation profile. Hasty SJ, Rath NP, Demchenko AV Pure and applied chemistry. Chimie pure et appliquee 29861508 Pure Appl Chem 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/29861508
Intramolecular glycosylation. Jia XG, Demchenko AV Beilstein journal of organic chemistry 29062425 Beilstein J Org Chem 2017 https://www.ncbi.nlm.nih.gov/pubmed/29062425
A pH sensitive thiolated β-cyclodextrin-modified nanoporous gold for controlled release of doxorubicin. Neupane D, Bhattarai JK, Demchenko AV, Stine KJ Journal of drug delivery science and technology 32922527 J Drug Deliv Sci Technol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32922527
HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation. Panza M, Stine KJ, Demchenko AV Chemical communications (Cambridge, England) 31930269 Chem Commun (Camb) 2020 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/31930269
A Streamlined Regenerative Glycosylation Reaction: Direct, Acid-Free Activation of Thioglycosides. Escopy S, Singh Y, Stine KJ, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 32804435 Chemistry 2021 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/32804435
Chemical synthesis of human milk oligosaccharides: lacto-N-neohexaose (Galβ1 → 4GlcNAcβ1→)(2) 3,6Galβ1 → 4Glc. Bandara MD, Stine KJ, Demchenko AV Organic & biomolecular chemistry 32048706 Org Biomol Chem 2020 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/32048706
Bromine-Promoted Glycosidation of Conformationally Superarmed Thioglycosides. Panza M, Civera M, Yasomanee JP, Belvisi L, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 31286579 Chemistry 2019 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/31286579
Investigation of Glycosyl Nitrates as Building Blocks for Chemical Glycosylation. Wang T, Singh Y, Stine KJ, Demchenko AV European journal of organic chemistry 31341403 European J Org Chem 2018 Dec 19 https://www.ncbi.nlm.nih.gov/pubmed/31341403
Chemical Synthesis of Human Milk Oligosaccharides: Lacto-N-hexaose Galβ1→3GlcNAcβ1→3 [Galβ1→4GlcNAcβ1→6] Galβ1→4Glc. Bandara MD, Stine KJ, Demchenko AV The Journal of organic chemistry 31749363 J Org Chem 2019 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/31749363
Comparative Study on the Effects of Picoloyl Groups in Sialylations Based on Their Substitution Pattern. Jones B, Behm A, Shadrick M, Geringer SA, Escopy S, Lohman M, De Meo C The Journal of organic chemistry 31718181 J Org Chem 2019 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/31718181
Iron(iii) chloride-catalyzed activation of glycosyl chlorides. Geringer SA, Demchenko AV Organic & biomolecular chemistry 30430182 Org Biomol Chem 2018 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/30430182
HPLC-Based Automated Synthesis and Purification of Carbohydrates. Kashiwagi GA, Petrosilli L, Escopy S, Lay L, Stine KJ, De Meo C, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 38684455 Chemistry 2024 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/38684455
Facile and robust methods for the regioselective acylation of N-acetylneuraminic acid. Shadrick M, Yu C, Geringer S, Ritter S, Behm A, Cox A, Lohman M, De Meo C New journal of chemistry = Nouveau journal de chimie 30147293 New J Chem 2018 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/30147293
Synthesis of 2-azido-2-deoxy- and 2-acetamido-2-deoxy-D-manno derivatives as versatile building blocks. Alex C, Visansirikul S, Zhang Y, Yasomanee JP, Codee J, Demchenko AV Carbohydrate research 31901454 Carbohydr Res 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31901454
The chemical synthesis of human milk oligosaccharides: Lacto-N-tetraose (Galβ1→3GlcNAcβ1→3Galβ1→4Glc). Bandara MD, Stine KJ, Demchenko AV Carbohydrate research 31585319 Carbohydr Res 2019 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/31585319
The chemical synthesis of human milk oligosaccharides: Lacto-N-neotetraose (Galβ1→4GlcNAcβ1→3Galβ1→4Glc). Bandara MD, Stine KJ, Demchenko AV Carbohydrate research 31319351 Carbohydr Res 2019 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31319351
Triflic acid-mediated synthesis of thioglycosides. Escopy S, Singh Y, Demchenko AV Organic & biomolecular chemistry 31490529 Org Biomol Chem 2019 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/31490529
Glycosyl nitrates in synthesis: streamlined access to glucopyranose building blocks differentiated at C-2. Wang T, Nigudkar SS, Yasomanee JP, Rath NP, Stine KJ, Demchenko AV Organic & biomolecular chemistry 29693690 Org Biomol Chem 2018 May 15 https://www.ncbi.nlm.nih.gov/pubmed/29693690
Automated Chemical Oligosaccharide Synthesis: Novel Approach to Traditional Challenges. Panza M, Pistorio SG, Stine KJ, Demchenko AV Chemical reviews 29953217 Chem Rev 2018 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/29953217
Koenigs-Knorr Glycosylation Reaction Catalyzed by Trimethylsilyl Trifluoromethanesulfonate. Singh Y, Demchenko AV Chemistry (Weinheim an der Bergstrasse, Germany) 30407673 Chemistry 2019 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/30407673
Immobilization of glycans on solid surfaces for application in glycomics. O'Neil CL, Stine KJ, Demchenko AV Journal of carbohydrate chemistry 30505067 J Carbohydr Chem 2018 https://www.ncbi.nlm.nih.gov/pubmed/30505067
The development of a dedicated polymer support for the solid-phase oligosaccharide synthesis. Panza M , Neupane D , Stine KJ , Demchenko AV Chemical communications (Cambridge, England) 32785304 Chem Commun (Camb) 2020 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/32785304
Regenerative Glycosylation. Singh Y, Wang T, Geringer SA, Stine KJ, Demchenko AV The Journal of organic chemistry 29227649 J Org Chem 2018 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/29227649
Manual and Automated Syntheses of the N-Linked Glycoprotein Core Glycans. Pistorio SG, Geringer SA, Stine KJ, Demchenko AV The Journal of organic chemistry 31066275 J Org Chem 2019 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/31066275
Synthesis of carbohydrate building blocks via regioselective uniform protection/deprotection strategies. Wang T, Demchenko AV Organic & biomolecular chemistry 31044205 Org Biomol Chem 2019 May 28 https://www.ncbi.nlm.nih.gov/pubmed/31044205
Application of Porous Materials to Carbohydrate Chemistry and Glycoscience. Stine KJ Advances in carbohydrate chemistry and biochemistry 29173727 Adv Carbohydr Chem Biochem 2017 https://www.ncbi.nlm.nih.gov/pubmed/29173727
Sialidase-catalyzed one-pot multienzyme (OPME) synthesis of sialidase transition-state analogue inhibitors. Xiao A, Li Y, Li X, Santra A, Yu H, Li W, Chen X ACS catalysis 29713561 ACS Catal 2018 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/29713561
Chemoenzymatic synthesis of Neu5Ac9NAc-containing α2-3- and α2-6-linked sialosides and their use for sialidase substrate specificity studies. Li W, Xiao A, Li Y, Yu H, Chen X Carbohydrate research 28961426 Carbohydr Res 2017 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/28961426
Catalytic Cycle of Neisseria meningitidis CMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography. Matthews MM, McArthur JB, Li Y, Yu H, Chen X, Fisher AJ Biochemistry 31583886 Biochemistry 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31583886
Converting Pasteurella multocidaα2-3-sialyltransferase 1 (PmST1) to a regioselective α2-6-sialyltransferase by saturation mutagenesis and regioselective screening. McArthur JB, Yu H, Zeng J, Chen X Organic & biomolecular chemistry 28134951 Org Biomol Chem 2017 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/28134951
Process Engineering and Glycosyltransferase Improvement for Short Route Chemoenzymatic Total Synthesis of GM1 Gangliosides. Yu H, Zhang L, Yang X, Bai Y, Chen X Chemistry (Weinheim an der Bergstrasse, Germany) 36596720 Chemistry 2023 May 2 https://www.ncbi.nlm.nih.gov/pubmed/36596720
Substrate and Process Engineering for Biocatalytic Synthesis and Facile Purification of Human Milk Oligosaccharides. Bai Y, Yang X, Yu H, Chen X ChemSusChem 35100486 ChemSusChem 2022 May 6 https://www.ncbi.nlm.nih.gov/pubmed/35100486
Chemoenzymatic Synthesis of N-Acetyl Analogues of 9-O-Acetylated b-Series Gangliosides. Yu H, Zheng Z, Zhang L, Yang X, Varki A, Chen X Tetrahedron 37981995 Tetrahedron 2023 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/37981995
Chemoenzymatic synthesis of para-nitrophenol (pNP)-tagged α2-8-sialosides and high-throughput substrate specificity studies of α2-8-sialidases. Tasnima N, Yu H, Li Y, Santra A, Chen X Organic & biomolecular chemistry 27924345 Org Biomol Chem 2016 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/27924345
Recent progress in synthesis of carbohydrates with sugar nucleotide-dependent glycosyltransferases. Na L, Li R, Chen X Current opinion in chemical biology 33310623 Curr Opin Chem Biol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33310623
One-pot multienzyme (OPME) chemoenzymatic synthesis of brain ganglioside glycans with human ST3GAL II expressed in E. coli. Yang X, Yu H, Yang X, Kooner AS, Yuan Y, Luu B, Chen X ChemCatChem 35784007 ChemCatChem 2022 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/35784007
Strategies for chemoenzymatic synthesis of carbohydrates. Li W, McArthur JB, Chen X Carbohydrate research 30529493 Carbohydr Res 2019 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/30529493
Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. Kooner AS, Yu H, Chen X Frontiers in immunology 31555264 Front Immunol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31555264
Facile chemoenzymatic synthesis of Lewis a (Le(a)) antigen in gram-scale and sialyl Lewis a (sLe(a)) antigens containing diverse sialic acid forms. Tasnima N, Yu H, Yan X, Li W, Xiao A, Chen X Carbohydrate research 30562693 Carbohydr Res 2019 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/30562693
H. pylori α1-3/4-fucosyltransferase (Hp3/4FT)-catalyzed one-pot multienzyme (OPME) synthesis of Lewis antigens and human milk fucosides. Yu H, Li Y, Wu Z, Li L, Zeng J, Zhao C, Wu Y, Tasnima N, Wang J, Liu H, Gadi MR, Guan W, Wang PG, Chen X Chemical communications (Cambridge, England) 28936496 Chem Commun (Camb) 2017 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/28936496
Chemoenzymatic Total Synthesis of GM3 Gangliosides Containing Different Sialic Acid Forms and Various Fatty Acyl Chains. Yu H, Gadi MR, Bai Y, Zhang L, Li L, Yin J, Wang PG, Chen X The Journal of organic chemistry 34152144 J Org Chem 2021 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/34152144
Chemoenzymatic Synthesis and Facile Purification of Gangliosides. Bai Y, Yu H, Chen X Current protocols 33760402 Curr Protoc 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33760402
A Bacterial β1-3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-N-tetraose (LNT) and Its Fucosides. McArthur JB, Yu H, Chen X ACS catalysis 33408950 ACS Catal 2019 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/33408950
Recent progress in chemical synthesis of bacterial surface glycans. Li R, Yu H, Chen X Current opinion in chemical biology 32920523 Curr Opin Chem Biol 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32920523
Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens. Yu H, Santra A, Li Y, McArthur JB, Ghosh T, Yang X, Wang PG, Chen X Organic & biomolecular chemistry 29789847 Org Biomol Chem 2018 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/29789847
Directed Evolution of Therapeutic Antibodies Targeting Glycosylation in Cancer. Amon R, Rosenfeld R, Perlmutter S, Grant OC, Yehuda S, Borenstein-Katz A, Alcalay R, Marshanski T, Yu H, Diskin R, Woods RJ, Chen X, Padler-Karavani V Cancers 33007970 Cancers (Basel) 2020 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/33007970
Biochemical characterization of Helicobacter pylori α1-3-fucosyltransferase and its application in the synthesis of fucosylated human milk oligosaccharides. Bai J, Wu Z, Sugiarto G, Gadi MR, Yu H, Li Y, Xiao C, Ngo A, Zhao B, Chen X, Guan W Carbohydrate research 31132553 Carbohydr Res 2019 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/31132553
Regioselective One-Pot Multienzyme (OPME) Chemoenzymatic Strategies for Systematic Synthesis of Sialyl Core 2 Glycans. Santra A, Li Y, Ghosh T, Li R, Yu H, Chen X ACS catalysis 31304048 ACS Catal 2019 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/31304048
Highly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc(4)βCer. Santra A, Li Y, Yu H, Slack TJ, Wang PG, Chen X Chemical communications (Cambridge, England) 28695219 Chem Commun (Camb) 2017 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/28695219
Advancing Chemoenzymatic Synthesis and Covalent Immobilization of a Comprehensive Ganglio-glycosphingolipid Library Enables Functional Multiplex Bead Assays. Gucchait A, Fu J, Zhang L, Agrahari AK, Zheng Z, Yang X, Yu H, Yang X, Varki A, Chen X Journal of the American Chemical Society 41017468 J Am Chem Soc 2025 Oct 8 https://www.ncbi.nlm.nih.gov/pubmed/41017468
An Improved Approach to the Direct Construction of 2-Deoxy-β-Linked Sugars: Applications to Oligosaccharide Synthesis. Lloyd D, Bennett CS Chemistry (Weinheim an der Bergstrasse, Germany) 29572995 Chemistry 2018 May 28 https://www.ncbi.nlm.nih.gov/pubmed/29572995
Challenges in the Conversion of Manual Processes to Machine-Assisted Syntheses: Activation of Thioglycoside Donors with Aryl(trifluoroethyl)iodonium Triflimide. Saliba RC, Wooke ZJ, Nieves GA, Chu AA, Bennett CS, Pohl NLB Organic letters 29336575 Org Lett 2018 Feb 2 https://www.ncbi.nlm.nih.gov/pubmed/29336575
Reagent-Controlled α-Selective Dehydrative Glycosylation of 2,6-Dideoxy Sugars: Construction of the Arugomycin Tetrasaccharide. Romeo JR, McDermott L, Bennett CS Organic letters 32281384 Org Lett 2020 May 1 https://www.ncbi.nlm.nih.gov/pubmed/32281384
Automated, Multistep Continuous-Flow Synthesis of 2,6-Dideoxy and 3-Amino-2,3,6-trideoxy Monosaccharide Building Blocks. Yalamanchili S, Nguyen TA, Zsikla A, Stamper G, DeYong AE, Florek J, Vasquez O, Pohl NLB, Bennett CS Angewandte Chemie (International ed. in English) 34463017 Angew Chem Int Ed Engl 2021 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/34463017
Matching Glycosyl Donor Reactivity to Sulfonate Leaving Group Ability Permits S(N)2 Glycosylations. Zhuo MH, Wilbur DJ, Kwan EE, Bennett CS Journal of the American Chemical Society 31550879 J Am Chem Soc 2019 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/31550879
Rapid de Novo Preparation of 2,6-Dideoxy Sugar Libraries through Gold-Catalyzed Homopropargyl Orthoester Cyclization. Yalamanchili S, Miller W, Chen X, Bennett CS Organic letters 31755271 Org Lett 2019 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/31755271
Synthesis of the Hexasaccharide Fragment of Landomycin A Using a Mild, Reagent-Controlled Approach. Yalamanchili S, Lloyd D, Bennett CS Organic letters 31021647 Org Lett 2019 May 17 https://www.ncbi.nlm.nih.gov/pubmed/31021647
Reagent Controlled Direct Dehydrative Glycosylation with 2-Deoxy Sugars: Construction of the Saquayamycin Z Pentasaccharide. Mizia JC, Bennett CS Organic letters 31305082 Org Lett 2019 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/31305082
Glycosyl Sulfonates Beyond Triflates. Bennett CS Chemical record (New York, N.Y.) 34142755 Chem Rec 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34142755
Modular continuous flow synthesis of orthogonally protected 6-deoxy glucose glycals. Yalamanchili S, Nguyen TV, Pohl NLB, Bennett CS Organic & biomolecular chemistry 32293636 Org Biomol Chem 2020 May 6 https://www.ncbi.nlm.nih.gov/pubmed/32293636
Versatile Glycosyl Sulfonates in β-Selective C-Glycosylation. Ling J, Bennett CS Angewandte Chemie (International ed. in English) 31880395 Angew Chem Int Ed Engl 2020 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/31880395
Recent Developments in Stereoselective Chemical Glycosylation. Ling J, Bennett CS Asian journal of organic chemistry 31534883 Asian J Org Chem 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31534883
Methods for 2-Deoxyglycoside Synthesis. Bennett CS, Galan MC Chemical reviews 29953219 Chem Rev 2018 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/29953219
Transformation of aldehydes into nitriles in an aqueous medium using O-phenylhydroxylamine as the nitrogen source. Cheewawisuttichai T, Hurst RD, Brichacek M Carbohydrate research 33761407 Carbohydr Res 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33761407
Expanding Glycomic Investigations through Thiol-Derivatized Glycans. Hurst RD, Nieves A, Brichacek M Molecules (Basel, Switzerland) 36838944 Molecules 2023 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/36838944
Development of a multifunctional neoglycoside auxiliary for applications in glycomics research. Cheewawisuttichai T, Brichacek M Organic & biomolecular chemistry 34264248 Org Biomol Chem 2021 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/34264248
Emerging structural insights into glycosyltransferase-mediated synthesis of glycans. Moremen KW, Haltiwanger RS Nature chemical biology 31427814 Nat Chem Biol 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31427814
Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy. Liu L, Prudden AR, Capicciotti CJ, Bosman GP, Yang JY, Chapla DG, Moremen KW, Boons GJ Nature chemistry 30532014 Nat Chem 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30532014
Chemoenzymatic Synthesis of Campylobacter jejuni Lipo-oligosaccharide Core Domains to Examine Guillain-Barré Syndrome Serum Antibody Specificities. Li T, Wolfert MA, Wei N, Huizinga R, Jacobs BC, Boons GJ Journal of the American Chemical Society 33164488 J Am Chem Soc 2020 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/33164488
Improved isolation and characterization procedure of sialylglycopeptide from egg yolk powder. Liu L, Prudden AR, Bosman GP, Boons GJ Carbohydrate research 29096185 Carbohydr Res 2017 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/29096185
An automated platform for the enzyme-mediated assembly of complex oligosaccharides. Li T, Liu L, Wei N, Yang JY, Chapla DG, Moremen KW, Boons GJ Nature chemistry 30792508 Nat Chem 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30792508
Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses. Broszeit F, van Beek RJ, Unione L, Bestebroer TM, Chapla D, Yang JY, Moremen KW, Herfst S, Fouchier RAM, de Vries RP, Boons GJ Nature communications 34521834 Nat Commun 2021 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/34521834
Guillain-Barré syndrome: expanding the concept of molecular mimicry. Laman JD, Huizinga R, Boons GJ, Jacobs BC Trends in immunology 35256276 Trends Immunol 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35256276
Appropriate aglycone modification significantly expands the glycan substrate acceptability of α1,6-fucosyltransferase (FUT8). Zhang R, Yang Q, Boruah BM, Zong G, Li C, Chapla D, Yang JY, Moremen KW, Wang LX The Biochemical journal 33734311 Biochem J 2021 Apr 30 https://www.ncbi.nlm.nih.gov/pubmed/33734311
Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function. Sheikh MO, Capicciotti CJ, Liu L, Praissman J, Ding D, Mead DG, Brindley MA, Willer T, Campbell KP, Moremen KW, Wells L, Boons GJ Nature communications 35750689 Nat Commun 2022 Jun 24 https://www.ncbi.nlm.nih.gov/pubmed/35750689
Chemoenzymatic Tagging of Tn/TF/STF Antigens in Living Systems. Yang Y, Chen M, Wu M, Hong S, Gao B, Liu Y, Yu C, Young TS, Chapla DG, Yang JY, Cappiello JR, Li JP, Sharpless KB, Moremen KW, Wu P Israel journal of chemistry 38737670 Isr J Chem 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/38737670
Chemoenzymatic Synthesis of Asymmetrical Multi-Antennary N-Glycans to Dissect Glycan-Mediated Interactions between Human Sperm and Oocytes. Chinoy ZS, Friscourt F, Capicciotti CJ, Chiu P, Boons GJ Chemistry (Weinheim an der Bergstrasse, Germany) 29603480 Chemistry 2018 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/29603480
Enantio- and Diastereoselective Synthesis of Hydroxy Bis(boronates) via Cu-Catalyzed Tandem Borylation/1,2-Addition. Green JC, Joannou MV, Murray SA, Zanghi JM, Meek SJ ACS catalysis 29520326 ACS Catal 2017 https://www.ncbi.nlm.nih.gov/pubmed/29520326
Diastereoselective sp(3) C-O Bond Formation via Visible Light-Induced, Copper-Catalyzed Cross-Couplings of Glycosyl Bromides with Aliphatic Alcohols. Yu F, Dickson JL, Loka RS, Xu H, Schaugaard RN, Schlegel HB, Luo L, Nguyen HM ACS catalysis 34168901 ACS Catal 2020 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/34168901
Phenanthroline-Catalyzed Stereoselective Formation of α-1,2-cis 2-Deoxy-2-Fluoro Glycosides. DeMent PM, Liu C, Wakpal J, Schaugaard RN, Schlegel HB, Nguyen HM ACS catalysis 34336371 ACS Catal 2021 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/34336371
Phenanthroline-Catalyzed Stereoretentive Glycosylations. Yu F, Li J, DeMent PM, Tu YJ, Schlegel HB, Nguyen HM Angewandte Chemie (International ed. in English) 30920099 Angew Chem Int Ed Engl 2019 May 20 https://www.ncbi.nlm.nih.gov/pubmed/30920099
An OGA-Resistant Probe Allows Specific Visualization and Accurate Identification of O-GlcNAc-Modified Proteins in Cells. Li J, Wang J, Wen L, Zhu H, Li S, Huang K, Jiang K, Li X, Ma C, Qu J, Parameswaran A, Song J, Zhao W, Wang PG ACS chemical biology 27622469 ACS Chem Biol 2016 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/27622469
A One-Step Chemoenzymatic Labeling Strategy for Probing Sialylated Thomsen-Friedenreich Antigen. Wen L, Liu D, Zheng Y, Huang K, Cao X, Song J, Wang PG ACS central science 29721527 ACS Cent Sci 2018 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/29721527
Sialic acid linkage-specific permethylation for improved profiling of protein glycosylation by MALDI-TOF MS. Jiang K, Zhu H, Li L, Guo Y, Gashash E, Ma C, Sun X, Li J, Zhang L, Wang PG Analytica chimica acta 28693729 Anal Chim Acta 2017 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/28693729
Machine-Driven Chemoenzymatic Synthesis of Glycopeptide. Zhang J, Liu D, Saikam V, Gadi MR, Gibbons C, Fu X, Song H, Yu J, Kondengaden SM, Wang PG, Wen L Angewandte Chemie (International ed. in English) 32677091 Angew Chem Int Ed Engl 2020 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/32677091
Facile Chemoenzymatic Synthesis of O-Mannosyl Glycans. Wang S, Zhang Q, Chen C, Guo Y, Gadi MR, Yu J, Westerlind U, Liu Y, Cao X, Wang PG, Li L Angewandte Chemie (International ed. in English) 29732660 Angew Chem Int Ed Engl 2018 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/29732660
Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia. Li J, Li S, Guo J, Li Q, Long J, Ma C, Ding Y, Yan C, Li L, Wu Z, Zhu H, Li KK, Wen L, Zhang Q, Xue Q, Zhao C, Liu N, Ivanov I, Luo M, Xi R, Long H, Wang PG, Chen Y Journal of medicinal chemistry 29641204 J Med Chem 2018 May 10 https://www.ncbi.nlm.nih.gov/pubmed/29641204
Chemoenzymatic modular assembly of O-GalNAc glycans for functional glycomics. Wang S, Chen C, Gadi MR, Saikam V, Liu D, Zhu H, Bollag R, Liu K, Chen X, Wang F, Wang PG, Ling P, Guan W, Li L Nature communications 34117223 Nat Commun 2021 Jun 11 https://www.ncbi.nlm.nih.gov/pubmed/34117223
Machine-Driven Enzymatic Oligosaccharide Synthesis by Using a Peptide Synthesizer. Zhang J, Chen C, Gadi MR, Gibbons C, Guo Y, Cao X, Edmunds G, Wang S, Liu D, Yu J, Wen L, Wang PG Angewandte Chemie (International ed. in English) 30375138 Angew Chem Int Ed Engl 2018 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/30375138
Toward Automated Enzymatic Synthesis of Oligosaccharides. Wen L, Edmunds G, Gibbons C, Zhang J, Gadi MR, Zhu H, Fang J, Liu X, Kong Y, Wang PG Chemical reviews 30011195 Chem Rev 2018 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/30011195
Chemoenzymatic synthesis of the bacterial polysaccharide repeating unit undecaprenyl pyrophosphate and its analogs. Li L, Woodward RL, Han W, Qu J, Song J, Ma C, Wang PG Nature protocols 27336706 Nat Protoc 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27336706
Site-Directed Glycosylation of Peptide/Protein with Homogeneous O-Linked Eukaryotic N-Glycans. Wu Z, Jiang K, Zhu H, Ma C, Yu Z, Li L, Guan W, Liu Y, Zhu H, Chen Y, Li S, Li J, Cheng J, Zhang L, Wang PG Bioconjugate chemistry 27529638 Bioconjug Chem 2016 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/27529638
Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes. Wu Z, Liu Y, Ma C, Li L, Bai J, Byrd-Leotis L, Lasanajak Y, Guo Y, Wen L, Zhu H, Song J, Li Y, Steinhauer DA, Smith DF, Zhao B, Chen X, Guan W, Wang PG Organic & biomolecular chemistry 27752690 Org Biomol Chem 2016 Nov 29 https://www.ncbi.nlm.nih.gov/pubmed/27752690
Microarray analyses of closely related glycoforms reveal different accessibilities of glycan determinants on N-glycan branches. Li L, Guan W, Zhang G, Wu Z, Yu H, Chen X, Wang PG Glycobiology 32026940 Glycobiology 2020 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/32026940
Identifying Sialylation Linkages at the Glycopeptide Level by Glycosyltransferase Labeling Assisted Mass Spectrometry (GLAMS). Zhu H, Wang S, Liu D, Ding L, Chen C, Liu Y, Wu Z, Bollag R, Liu K, Alexander WM, Yin J, Ma C, Li L, Wang PG Analytical chemistry 32271005 Anal Chem 2020 May 5 https://www.ncbi.nlm.nih.gov/pubmed/32271005
Decoding glycan protein interactions by a new class of asymmetric N-glycans. Wu Z, Liu Y, Li L, Wan XF, Zhu H, Guo Y, Wei M, Guan W, Wang PG Organic & biomolecular chemistry 29043371 Org Biomol Chem 2017 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/29043371
Substrate specificity of FUT8 and chemoenzymatic synthesis of core-fucosylated asymmetric N-glycans. Calderon AD, Liu Y, Li X, Wang X, Chen X, Li L, Wang PG Organic & biomolecular chemistry 27080952 Org Biomol Chem 2016 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/27080952
Biochemical characterization of an α1,2-colitosyltransferase from Escherichia coli O55:H7. Wu Z, Zhao G, Li T, Qu J, Guan W, Wang J, Ma C, Li X, Zhao W, Wang PG, Li L Glycobiology 26703456 Glycobiology 2016 May https://www.ncbi.nlm.nih.gov/pubmed/26703456
Chemoenzymatic Synthesis of a Library of Human Milk Oligosaccharides. Xiao Z, Guo Y, Liu Y, Li L, Zhang Q, Wen L, Wang X, Kondengaden SM, Wu Z, Zhou J, Cao X, Li X, Ma C, Wang PG The Journal of organic chemistry 27305319 J Org Chem 2016 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/27305319
An enzymatic strategy to asymmetrically branched N-glycans. Calderon AD, Zhou J, Guan W, Wu Z, Guo Y, Bai J, Li Q, Wang PG, Fang J, Li L Organic & biomolecular chemistry 28832049 Org Biomol Chem 2017 Sep 13 https://www.ncbi.nlm.nih.gov/pubmed/28832049
N-Linked Glycosylation Prevents Deamidation of Glycopeptide and Glycoprotein. Zhu HJ, Liu D, Tran VP, Wu Z, Jiang K, Zhu H, Zhang J, Gibbons C, Xue B, Shi H, Wang PG ACS chemical biology 33270417 ACS Chem Biol 2020 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/33270417
Synthetic oligosaccharides can replace animal-sourced low-molecular weight heparins. Xu Y, Chandarajoti K, Zhang X, Pagadala V, Dou W, Hoppensteadt DM, Sparkenbaugh EM, Cooley B, Daily S, Key NS, Severynse-Stevens D, Fareed J, Linhardt RJ, Pawlinski R, Liu J Science translational medicine 28878012 Sci Transl Med 2017 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/28878012
Tools for mammalian glycoscience research. Griffin ME, Hsieh-Wilson LC Cell 35809571 Cell 2022 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/35809571
Divergent Synthesis of Heparan Sulfate Oligosaccharides. Dulaney SB, Xu Y, Wang P, Tiruchinapally G, Wang Z, Kathawa J, El-Dakdouki MH, Yang B, Liu J, Huang X The Journal of organic chemistry 26574650 J Org Chem 2015 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/26574650
Synthesis of 3-O-Sulfated Oligosaccharides to Understand the Relationship between Structures and Functions of Heparan Sulfate. Wang Z, Hsieh PH, Xu Y, Thieker D, Chai EJE, Xie S, Cooley B, Woods RJ, Chi L, Liu J Journal of the American Chemical Society 28340300 J Am Chem Soc 2017 Apr 12 https://www.ncbi.nlm.nih.gov/pubmed/28340300
Obstacles and solutions for chemical synthesis of syndecan-3 (53-62) glycopeptides with two heparan sulfate chains. Yang W, Yoshida K, Yang B, Huang X Carbohydrate research 27810711 Carbohydr Res 2016 Nov 29 https://www.ncbi.nlm.nih.gov/pubmed/27810711
Synthesis of a Systematic 64-Membered Heparan Sulfate Tetrasaccharide Library. Baryal KN, Ramadan S, Su G, Huo C, Zhao Y, Liu J, Hsieh-Wilson LC, Huang X Angewandte Chemie (International ed. in English) 36173931 Angew Chem Int Ed Engl 2023 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/36173931
Homoserine as an Aspartic Acid Precursor for Synthesis of Proteoglycan Glycopeptide Containing Aspartic Acid and a Sulfated Glycan Chain. Yang W, Ramadan S, Yang B, Yoshida K, Huang X The Journal of organic chemistry 27809505 J Org Chem 2016 Dec 2 https://www.ncbi.nlm.nih.gov/pubmed/27809505
Synthesis of Chondroitin Sulfate A Bearing Syndecan-1 Glycopeptide. Ramadan S, Yang W, Zhang Z, Huang X Organic letters 28849661 Org Lett 2017 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/28849661
Automated Solid Phase Assisted Synthesis of a Heparan Sulfate Disaccharide Library. Ramadan S, Su G, Baryal K, Hsieh-Wilson LC, Liu J, Huang X Organic chemistry frontiers : an international journal of organic chemistry 36212917 Org Chem Front 2022 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/36212917
Expedient Synthesis of a Library of Heparan Sulfate-Like "Head-to-Tail" Linked Multimers for Structure and Activity Relationship Studies. Zhang J, Liang L, Yang W, Ramadan S, Baryal K, Huo CX, Bernard JJ, Liu J, Hsieh-Wilson L, Zhang F, Linhardt RJ, Huang X Angewandte Chemie (International ed. in English) 36199167 Angew Chem Int Ed Engl 2022 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/36199167
Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly. Pawar NJ, Wang L, Higo T, Bhattacharya C, Kancharla PK, Zhang F, Baryal K, Huo CX, Liu J, Linhardt RJ, Huang X, Hsieh-Wilson LC Angewandte Chemie (International ed. in English) 31553820 Angew Chem Int Ed Engl 2019 Dec 16 https://www.ncbi.nlm.nih.gov/pubmed/31553820
Preactivation-based chemoselective glycosylations: A powerful strategy for oligosaccharide assembly. Yang W, Yang B, Ramadan S, Huang X Beilstein journal of organic chemistry 29062430 Beilstein J Org Chem 2017 https://www.ncbi.nlm.nih.gov/pubmed/29062430
Binding and neurotoxicity mitigation of toxic tau oligomers by synthetic heparin like oligosaccharides. Wang P , Lo Cascio F , Gao J , Kayed R , Huang X Chemical communications (Cambridge, England) 30128457 Chem Commun (Camb) 2018 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/30128457
Efficient platform for synthesizing comprehensive heparan sulfate oligosaccharide libraries for decoding glycosaminoglycan-protein interactions. Wang L, Sorum AW, Huang BS, Kern MK, Su G, Pawar N, Huang X, Liu J, Pohl NLB, Hsieh-Wilson LC Nature chemistry 37349377 Nat Chem 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37349377
Recent advances in the synthesis of extensive libraries of heparan sulfate oligosaccharides for structure-activity relationship studies. Ramadan S, Mayieka M, Pohl NLB, Liu J, Hsieh-Wilson LC, Huang X Current opinion in chemical biology 38636446 Curr Opin Chem Biol 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38636446
Anthranilic Acid as a Versatile Fluorescent Tag and Linker for Functional Glycomics. Zhu Y, Liu X, Zhang Y, Wang Z, Lasanajak Y, Song X Bioconjugate chemistry 30380836 Bioconjug Chem 2018 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/30380836
Sensitive and robust MALDI-TOF-MS glycomics analysis enabled by Girard's reagent T on-target derivatization (GTOD) of reducing glycans. Zhang Y, Wang B, Jin W, Wen Y, Nan L, Yang M, Liu R, Zhu Y, Wang C, Huang L, Song X, Wang Z Analytica chimica acta 30598139 Anal Chim Acta 2019 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/30598139
Preparative scale purification of natural glycans by closed-loop recycle HPLC. Zhu Y, Bowen TJ, Song X Analytical biochemistry 32277906 Anal Biochem 2020 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/32277906
Oxidative release of natural glycans for functional glycomics. Song X, Ju H, Lasanajak Y, Kudelka MR, Smith DF, Cummings RD Nature methods 27135973 Nat Methods 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27135973
Preparation of Complex Glycans From Natural Sources for Functional Study. Zhang Q, Li Z, Song X Frontiers in chemistry 32719769 Front Chem 2020 https://www.ncbi.nlm.nih.gov/pubmed/32719769
Amplification and Preparation of Cellular O-Glycomes for Functional Glycomics. Li Z, Zhang Q, Ashline D, Zhu Y, Lasanajak Y, Chernova T, Reinhold V, Cummings RD, Wang PG, Ju T, Smith DF, Song X Analytical chemistry 32539345 Anal Chem 2020 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/32539345
History and future of shotgun glycomics. Smith DF, Cummings RD, Song X Biochemical Society transactions 30626702 Biochem Soc Trans 2019 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/30626702
Large scale preparation of high mannose and paucimannose N-glycans from soybean proteins by oxidative release of natural glycans (ORNG). Zhu Y, Yan M, Lasanajak Y, Smith DF, Song X Carbohydrate research 29803109 Carbohydr Res 2018 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/29803109
Regeneration of Free Reducing Glycans from Reductive Amination-Tagged Glycans by Oxone. Zhang Q, Wang S, Li Z, Lasanajak Y, Li L, Song X The Journal of organic chemistry 35143205 J Org Chem 2022 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/35143205
Next-Generation Glycan Microarray Enabled by DNA-Coded Glycan Library and Next-Generation Sequencing Technology. Yan M, Zhu Y, Liu X, Lasanajak Y, Xiong J, Lu J, Lin X, Ashline D, Reinhold V, Smith DF, Song X Analytical chemistry 31187982 Anal Chem 2019 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/31187982
Highly Selective β-Mannosylations and β-Rhamnosylations Catalyzed by Bis-thiourea. Li Q, Levi SM, Jacobsen EN Journal of the American Chemical Society 32527078 J Am Chem Soc 2020 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/32527078
Macrocyclic bis-thioureas catalyze stereospecific glycosylation reactions. Park Y, Harper KC, Kuhl N, Kwan EE, Liu RY, Jacobsen EN Science (New York, N.Y.) 28082586 Science 2017 Jan 13 https://www.ncbi.nlm.nih.gov/pubmed/28082586
Sensitive and Accurate (13)C Kinetic Isotope Effect Measurements Enabled by Polarization Transfer. Kwan EE, Park Y, Besser HA, Anderson TL, Jacobsen EN Journal of the American Chemical Society 28005341 J Am Chem Soc 2017 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/28005341
Stereospecific Furanosylations Catalyzed by Bis-thiourea Hydrogen-Bond Donors. Mayfield AB, Metternich JB, Trotta AH, Jacobsen EN Journal of the American Chemical Society 32013410 J Am Chem Soc 2020 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/32013410
Catalytic activation of glycosyl phosphates for stereoselective coupling reactions. Levi SM, Li Q, Rötheli AR, Jacobsen EN Proceedings of the National Academy of Sciences of the United States of America 30559190 Proc Natl Acad Sci U S A 2019 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/30559190
Site-selective, stereocontrolled glycosylation of minimally protected sugars. Li Q, Levi SM, Wagen CC, Wendlandt AE, Jacobsen EN Nature 35709829 Nature 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/35709829
Putting sugars under strain. Pohl N Science (New York, N.Y.) 31097651 Science 2019 May 17 https://www.ncbi.nlm.nih.gov/pubmed/31097651
Scope and limitations of carbohydrate hydrolysis for de novo glycan sequencing using a hydrogen peroxide/metallopeptide-based glycosidase mimetic. Peng T, Wooke Z, Pohl NLB Carbohydrate research 29475194 Carbohydr Res 2018 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/29475194
Recent Liquid Chromatographic Approaches and Developments for the Separation and Purification of Carbohydrates. Nagy G, Peng T, Pohl NLB Analytical methods : advancing methods and applications 28824713 Anal Methods 2017 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/28824713
Overcoming the limited availability of human milk oligosaccharides: challenges and opportunities for research and application. Bode L, Contractor N, Barile D, Pohl N, Prudden AR, Boons GJ, Jin YS, Jennewein S Nutrition reviews 27634978 Nutr Rev 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27634978
Protocol for the purification of protected carbohydrates: toward coupling automated synthesis to alternate-pump recycling high-performance liquid chromatography. Nagy G, Peng T, Kabotso DE, Novotny MV, Pohl NL Chemical communications (Cambridge, England) 27775116 Chem Commun (Camb) 2016 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/27775116
Recent Advances in the Analysis of Complex Glycoproteins. Gaunitz S, Nagy G, Pohl NL, Novotny MV Analytical chemistry 28105826 Anal Chem 2017 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/28105826
Automated Solution-Phase Synthesis of S-Glycosides for the Production of Oligomannopyranoside Derivatives. Kern MK, Pohl NLB Organic letters 32432478 Org Lett 2020 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/32432478
A High-Throughput Mass-Spectrometry-Based Assay for Identifying the Biochemical Functions of Putative Glycosidases. Peng T, Nagy G, Trinidad JC, Jackson JM, Pohl NLB Chembiochem : a European journal of chemical biology 28960712 Chembiochem 2017 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/28960712
Synthesis of protected glucose derivatives from levoglucosan by development of common carbohydrate protecting group reactions under continuous flow conditions. Marion KC, Wooke Z, Pohl NLB Carbohydrate research 30121415 Carbohydr Res 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30121415
Advancing Solutions to the Carbohydrate Sequencing Challenge. Gray CJ, Migas LG, Barran PE, Pagel K, Seeberger PH, Eyers CE, Boons GJ, Pohl NLB, Compagnon I, Widmalm G, Flitsch SL Journal of the American Chemical Society 31403778 J Am Chem Soc 2019 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/31403778
Introduction: Carbohydrate Chemistry. Pohl NLB Chemical reviews 30205688 Chem Rev 2018 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/30205688
Designing sugar mimetics: non-natural pyranosides as innovative chemical tools. Saliba RC, Pohl NL Current opinion in chemical biology 27621102 Curr Opin Chem Biol 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27621102
Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides. Miller MC, Cai C, Wichapong K, Bhaduri S, Pohl NLB, Linhardt RJ, Gabius HJ, Mayo KH Scientific reports 32973213 Sci Rep 2020 Sep 24 https://www.ncbi.nlm.nih.gov/pubmed/32973213
Expanding the Toolbox for Inducible Protein Expression With Automation-enabled Generation of Glycomimetics. DeYong AE, Marion KC, Ozturk M, Murali SK, Enam F, Mansell TJ, Pohl NLB Chemistry (Weinheim an der Bergstrasse, Germany) 41498688 Chemistry 2026 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/41498688
Isotopic labeling with cellular O-glycome reporter/amplification (ICORA) for comparative O-glycomics of cultured cells. Kudelka MR, Nairn AV, Sardar MY, Sun X, Chaikof EL, Ju T, Moremen KW, Cummings RD Glycobiology 29390058 Glycobiology 2018 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/29390058
Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo. Krishnamurthy VR, Sardar MY, Ying Y, Song X, Haller C, Dai E, Wang X, Hanjaya-Putra D, Sun L, Morikis V, Simon SI, Woods RJ, Cummings RD, Chaikof EL Nature communications 25824568 Nat Commun 2015 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/25824568
Intact quantitation and evaluation of a PEG-glycosulfopeptide as a therapeutic P-selectin antagonist. Park DD, Park SS, Dai E, Haller CA, Wong DJ, Wever WJ, Cummings RD, Chaikof EL RSC advances 39469021 RSC Adv 2024 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/39469021
Targeting P-selectin glycoprotein ligand-1/P-selectin interactions as a novel therapy for metabolic syndrome. Patel MS, Miranda-Nieves D, Chen J, Haller CA, Chaikof EL Translational research : the journal of laboratory and clinical medicine 28034759 Transl Res 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28034759
Immune checkpoint regulator: a new assignment proposed for the classic adhesion molecule P-selectin glycoprotein ligand-1. Chen J, Haller CA, Chaikof EL Translational cancer research 30613475 Transl Cancer Res 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/30613475
Insights Derived from the Synthesis of a Complex Core 2 Glycan. Dhakal B, Mandhapati A, Park S, Sun L, Chaikof EL The Journal of organic chemistry 39087956 J Org Chem 2024 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/39087956
Convergent Synthesis of Sialyl Lewis(X)- O-Core-1 Threonine. Sardar MYR, Mandhapati AR, Park S, Wever WJ, Cummings RD, Chaikof EL The Journal of organic chemistry 29638128 J Org Chem 2018 May 4 https://www.ncbi.nlm.nih.gov/pubmed/29638128
Synthesis of Lewis(X)-O-Core-1 threonine: A building block for O-linked Lewis(X) glycopeptides. Sardar MYR, Krishnamurthy VR, Park S, Mandhapati AR, Wever WJ, Park D, Cummings RD, Chaikof EL Carbohydrate research 29065342 Carbohydr Res 2017 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/29065342
A PSGL-1 glycomimetic reduces thrombus burden without affecting hemostasis. Wong DJ, Park DD, Park SS, Haller CA, Chen J, Dai E, Liu L, Mandhapati AR, Eradi P, Dhakal B, Wever WJ, Hanes M, Sun L, Cummings RD, Chaikof EL Blood 33945603 Blood 2021 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/33945603
Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow. Morikis VA, Chase S, Wun T, Chaikof EL, Magnani JL, Simon SI Blood 28811304 Blood 2017 Nov 9 https://www.ncbi.nlm.nih.gov/pubmed/28811304
Anomeric Fatty Acid Functionalization Prevents Nonenzymatic S-Glycosylation by Monosaccharide Metabolic Chemical Reporters. Pedowitz NJ, Jackson EG, Overhulse JM, McKenna CE, Kohler JJ, Pratt MR ACS chemical biology 34282887 ACS Chem Biol 2021 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/34282887
Disease-associated patterns of acetylation stabilize tau fibril formation. Li L, Nguyen BA, Mullapudi V, Li Y, Saelices L, Joachimiak LA Structure (London, England : 1993) 37348495 Structure 2023 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/37348495
Genome-Wide CRISPR Screening to Identify Mammalian Factors that Regulate Intron Retention. Scarborough AM, Govindan A, Conrad NK Methods in molecular biology (Clifton, N.J.) 35895270 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35895270
Synthesis of Cell-Permeable N-Acetylhexosamine 1-Phosphates. Kakde BN, Capota E, Kohler JJ, Tambar UK The Journal of organic chemistry 34618463 J Org Chem 2021 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/34618463
Disease-associated patterns of acetylation stabilize tau fibril formation. Li L, Nguyen B, Mullapudi V, Saelices L, Joachimiak LA bioRxiv : the preprint server for biology 36711822 bioRxiv 2023 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/36711822
The Disordered Amino Terminus of the Circadian Enzyme Nocturnin Modulates Its NADP(H) Phosphatase Activity by Changing Protein Dynamics. Wickramaratne AC, Li L, Hopkins JB, Joachimiak LA, Green CB Biochemistry 35535990 Biochemistry 2022 May 10 https://www.ncbi.nlm.nih.gov/pubmed/35535990
Photocrosslinking O-GlcNAcylated Proteins to Neighboring Biomolecules. Capota E, Wu H, Kohler JJ Current protocols 34288588 Curr Protoc 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34288588
SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing. Govindan A, Conrad NK bioRxiv : the preprint server for biology 39464125 bioRxiv 2025 Jan 30 https://www.ncbi.nlm.nih.gov/pubmed/39464125
Small molecule splicing modulators that disrupt O-GlcNAc homeostasis. Cheng SS, Mody AC, Vetere A, Govindan A, Lee Y, Khost DE, Narayan R, Sackton TB, Conrad NK, Wagner BK, Woo CM Nature communications 41526361 Nat Commun 2026 Jan 12 https://www.ncbi.nlm.nih.gov/pubmed/41526361
A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface. Wu H, Shajahan A, Yang JY, Capota E, Wands AM, Arthur CM, Stowell SR, Moremen KW, Azadi P, Kohler JJ Cell chemical biology 34331854 Cell Chem Biol 2022 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/34331854
What sugar does to your pores. Kohler JJ The Journal of cell biology 34132758 J Cell Biol 2021 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/34132758
SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing. Govindan A, Conrad NK eLife 40265571 Elife 2025 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/40265571
Alkylation of Galectin-1 with Iodoacetamide and Mass Spectrometric Mapping of the Sites of Incorporation. Wu SC, Paul A, Cummings RD, Feasley CL, Arthur CM, Stowell SR Methods in molecular biology (Clifton, N.J.) 35320520 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35320520
ABO blood group antigens and differential glycan expression: Perspective on the evolution of common human enzyme deficiencies. Jajosky RP, Wu SC, Zheng L, Jajosky AN, Jajosky PG, Josephson CD, Hollenhorst MA, Sackstein R, Cummings RD, Arthur CM, Stowell SR iScience 36691627 iScience 2023 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/36691627
Innate immune Galectin-7 specifically targets microbes that decorate themselves in blood group-like antigens. Wu SC, Kamili NA, Dias-Baruffi M, Josephson CD, Rathgeber MF, Yeung MY, Lane WJ, Wang J, Jan HM, Rakoff-Nahoum S, Cummings RD, Stowell SR, Arthur CM iScience 35754739 iScience 2022 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/35754739
Multifaceted role of glycosylation in transfusion medicine, platelets, and red blood cells. Lee-Sundlov MM, Stowell SR, Hoffmeister KM Journal of thrombosis and haemostasis : JTH 32350996 J Thromb Haemost 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32350996
Whole microbe arrays accurately predict interactions and overall antimicrobial activity of galectin-8 toward distinct strains of Streptococcus pneumoniae. Wu SC, Jan HM, Vallecillo-Zúniga ML, Rathgeber MF, Stowell CS, Murdock KL, Patel KR, Nakahara H, Stowell CJ, Nahm MH, Arthur CM, Cummings RD, Stowell SR Scientific reports 37005394 Sci Rep 2023 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/37005394
Purification of Recombinant Galectins from Different Species Using Distinct Affinity Chromatography Methods. Paul A, Wu SC, Patel KR, Ho AD, Allen JWL, Verkerke H, Arthur CM, Stowell SR Methods in molecular biology (Clifton, N.J.) 35320519 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35320519
Method for Identifying Galectin Ligands on Lymphocyte Membrane Glycoproteins. Patel KR, Barb AW, Stowell SR Methods in molecular biology (Clifton, N.J.) 35320529 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35320529
Generation and Use of Recombinant Galectins. Wu SC, Paul A, Ho A, Patel KR, Allen JWL, Verkerke H, Arthur CM, Stowell SR Current protocols 33656274 Curr Protoc 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33656274
Galectin-9 Is a Novel Regulator of Epithelial Restitution. Robinson BS, Saeedi B, Arthur CM, Owens J, Naudin C, Ahmed N, Luo L, Jones R, Neish A, Stowell SR The American journal of pathology 32380082 Am J Pathol 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32380082
The role of galectins in immunity and infection. Liu FT, Stowell SR Nature reviews. Immunology 36646848 Nat Rev Immunol 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/36646848
The Sweet-Side of Leukocytes: Galectins as Master Regulators of Neutrophil Function. Robinson BS, Arthur CM, Evavold B, Roback E, Kamili NA, Stowell CS, Vallecillo-Zúniga ML, Van Ry PM, Dias-Baruffi M, Cummings RD, Stowell SR Frontiers in immunology 31440233 Front Immunol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31440233
Evaluation of the Bactericidal Activity of Galectins. Kamili NA, Paul A, Wu SC, Dias-Baruffi M, Cummings RD, Arthur CM, Stowell SR Methods in molecular biology (Clifton, N.J.) 35320543 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35320543
Galectin-9 recognizes and exhibits antimicrobial activity toward microbes expressing blood group-like antigens. Blenda AV, Kamili NA, Wu SC, Abel WF, Ayona D, Gerner-Smidt C, Ho AD, Benian GM, Cummings RD, Arthur CM, Stowell SR The Journal of biological chemistry 35148986 J Biol Chem 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35148986
Full-Length Galectin-3 Is Required for High Affinity Microbial Interactions and Antimicrobial Activity. Wu SC, Ho AD, Kamili NA, Wang J, Murdock KL, Cummings RD, Arthur CM, Stowell SR Frontiers in microbiology 34690972 Front Microbiol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34690972
Aspartate Residues Far from the Active Site Drive O-GlcNAc Transferase Substrate Selection. Joiner CM, Levine ZG, Aonbangkhen C, Woo CM, Walker S Journal of the American Chemical Society 31373491 J Am Chem Soc 2019 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/31373491
Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase. Ge Y, Ramirez DH, Yang B, D'Souza AK, Aonbangkhen C, Wong S, Woo CM Nature chemical biology 33686291 Nat Chem Biol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33686291
Engineering a Proximity-Directed O-GlcNAc Transferase for Selective Protein O-GlcNAcylation in Cells. Ramirez DH, Aonbangkhen C, Wu HY, Naftaly JA, Tang S, O'Meara TR, Woo CM ACS chemical biology 32119511 ACS Chem Biol 2020 Apr 17 https://www.ncbi.nlm.nih.gov/pubmed/32119511
The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain. Mealer RG, Williams SE, Noel M, Yang B, D'Souza AK, Nakata T, Graham DB, Creasey EA, Cetinbas M, Sadreyev RI, Scolnick EM, Woo CM, Smoller JW, Xavier RJ, Cummings RD Molecular psychiatry 35260802 Mol Psychiatry 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35260802
The Crossroads of Glycoscience, Infection, and Immunology. McKitrick TR, Ackerman ME, Anthony RM, Bennett CS, Demetriou M, Hudalla GA, Ribbeck K, Ruhl S, Woo CM, Yang L, Zost SJ, Schnaar RL, Doering TL Frontiers in microbiology 34646251 Front Microbiol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34646251
Truncation of the TPR domain of OGT alters substrate and glycosite selection. Ramirez DH, Yang B, D'Souza AK, Shen D, Woo CM Analytical and bioanalytical chemistry 34725712 Anal Bioanal Chem 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34725712
Writing and erasing O-GlcNAc from target proteins in cells. Ge Y, Woo CM Biochemical Society transactions 34783346 Biochem Soc Trans 2021 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/34783346
The O-GlcNAc Modification on Kinases. Schwein PA, Woo CM ACS chemical biology 32155042 ACS Chem Biol 2020 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/32155042
O-GlcNAc Engineering on a Target Protein in Cells with Nanobody-OGT and Nanobody-splitOGA. Ramirez DH, Ge Y, Woo CM Current protocols 33950562 Curr Protoc 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33950562
O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins. Darabedian N, Yang B, Ding R, Cutolo G, Zaro BW, Woo CM, Pratt MR Frontiers in chemistry 32411667 Front Chem 2020 https://www.ncbi.nlm.nih.gov/pubmed/32411667
Small Molecule-Activated O-GlcNAcase for Spatiotemporal Removal of O-GlcNAc in Live Cells. Ge Y, Lu H, Yang B, Woo CM ACS chemical biology 36598936 ACS Chem Biol 2023 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/36598936
Writing and Erasing O-GlcNAc on Casein Kinase 2 Alpha Alters the Phosphoproteome. Schwein PA, Ge Y, Yang B, D'Souza A, Mody A, Shen D, Woo CM ACS chemical biology 35467332 ACS Chem Biol 2022 May 20 https://www.ncbi.nlm.nih.gov/pubmed/35467332
4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase. Jackson EG, Cutolo G, Yang B, Yarravarapu N, Burns MWN, Bineva-Todd G, Roustan C, Thoden JB, Lin-Jones HM, van Kuppevelt TH, Holden HM, Schumann B, Kohler JJ, Woo CM, Pratt MR ACS chemical biology 34931806 ACS Chem Biol 2022 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/34931806
On the Cutting Edge of Translational Research. Angel PM Clinical chemistry 33230521 Clin Chem 2021 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/33230521
Rapid N-Glycan Profiling of Serum and Plasma by a Novel Slide-Based Imaging Mass Spectrometry Workflow. Blaschke CRK, Black AP, Mehta AS, Angel PM, Drake RR Journal of the American Society for Mass Spectrometry 32809822 J Am Soc Mass Spectrom 2020 Dec 2 https://www.ncbi.nlm.nih.gov/pubmed/32809822
Spatial N-glycomics of the human aortic valve in development and pediatric endstage congenital aortic valve stenosis. Angel PM, Drake RR, Park Y, Clift CL, West C, Berkhiser S, Hardiman G, Mehta AS, Bichell DP, Su YR Journal of molecular and cellular cardiology 33516683 J Mol Cell Cardiol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33516683
Antibody Panel Based N-Glycan Imaging for N-Glycoprotein Biomarker Discovery. Black AP, Angel PM, Drake RR, Mehta AS Current protocols in protein science 31721442 Curr Protoc Protein Sci 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31721442
Pro-inflammatory IgG1 N-glycan signature correlates with primary graft dysfunction onset in COPD patients. McQuiston A, Scott D, Nord D, Langerude L, Pelaez A, Machuca T, Mehta A, Drake RR, Christie JD, Angel P, Atkinson C Transplant immunology 34767945 Transpl Immunol 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/34767945
Development of an Antibody-Based Platform for the Analysis of Immune Cell-Specific N-linked Glycosylation. Dressman JW, McDowell CT, Lu X, Angel PM, Drake RR, Mehta AS Analytical chemistry 37293957 Anal Chem 2023 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/37293957
The role of neuraminidase in TLR4-MAPK signalling and the release of cytokines by lupus serum-stimulated mesangial cells. Sundararaj K, Rodgers J, Angel P, Wolf B, Nowling TK Immunology 33314123 Immunology 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33314123
Applications and continued evolution of glycan imaging mass spectrometry. McDowell CT, Lu X, Mehta AS, Angel PM, Drake RR Mass spectrometry reviews 34392557 Mass Spectrom Rev 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/34392557
Protease-dependent defects in N-cadherin processing drive PMM2-CDG pathogenesis. Klaver EJ, Dukes-Rimsky L, Kumar B, Xia ZJ, Dang T, Lehrman MA, Angel P, Drake RR, Freeze HH, Steet R, Flanagan-Steet H JCI insight 34784297 JCI Insight 2021 Dec 22 https://www.ncbi.nlm.nih.gov/pubmed/34784297
Collagen fiber regulation in human pediatric aortic valve development and disease. Clift CL, Su YR, Bichell D, Jensen Smith HC, Bethard JR, Norris-Caneda K, Comte-Walters S, Ball LE, Hollingsworth MA, Mehta AS, Drake RR, Angel PM Scientific reports 33963260 Sci Rep 2021 May 7 https://www.ncbi.nlm.nih.gov/pubmed/33963260
Multiplexed imaging mass spectrometry of the extracellular matrix using serial enzyme digests from formalin-fixed paraffin-embedded tissue sections. Clift CL, Drake RR, Mehta A, Angel PM Analytical and bioanalytical chemistry 33206215 Anal Bioanal Chem 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33206215
Glycan Imaging Mass Spectrometry: Progress in Developing Clinical Diagnostic Assays for Tissues, Biofluids, and Cells. Blaschke CRK, McDowell CT, Black AP, Mehta AS, Angel PM, Drake RR Clinics in laboratory medicine 34020762 Clin Lab Med 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34020762
A Rapid Array-Based Approach to N-Glycan Profiling of Cultured Cells. Angel PM, Saunders J, Clift CL, White-Gilbertson S, Voelkel-Johnson C, Yeh E, Mehta A, Drake RR Journal of proteome research 31535553 J Proteome Res 2019 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/31535553
Metabolic Markers and Association of Biological Sex in Lupus Nephritis. Wolf B, Blaschke CRK, Mungaray S, Weselman BT, Stefanenko M, Fedoriuk M, Bai H, Rodgers J, Palygin O, Drake RR, Nowling TK International journal of molecular sciences 38003679 Int J Mol Sci 2023 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/38003679
Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression. Young LEA, Nietert PJ, Stubler R, Kittrell CG, Grimsley G, Lewin DN, Mehta AS, Hajar C, Wang K, O'Quinn EC, Angel PM, Wallace K, Drake RR Frontiers in pharmacology 38273829 Front Pharmacol 2023 https://www.ncbi.nlm.nih.gov/pubmed/38273829
Determining the N-Glycan and Collagen/Extracellular Matrix Protein Compositions in a Novel Outcome Cohort of Prostate Cancer Tissue Microarrays Using MALDI-MSI. Hartig JP, Bejar K, Young LEA, Grimsley G, Bethard JR, Troyer DA, Hernandez J, Wu JD, Ippolito JE, Ball LE, Gelfond JAL, Johnson-Pais TL, Mehta AS, Leach RJ, Angel PM, Drake RR Cancer research communications 39347566 Cancer Res Commun 2024 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/39347566
Set Up for Failure: Pre-Existing Autoantibodies in Lung Transplant. McQuiston A, Emtiazjoo A, Angel P, Machuca T, Christie J, Atkinson C Frontiers in immunology 34456920 Front Immunol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34456920
GlycoFibroTyper: A Novel Method for the Glycan Analysis of IgG and the Development of a Biomarker Signature of Liver Fibrosis. Scott DA, Wang M, Grauzam S, Pippin S, Black A, Angel PM, Drake RR, Castellino S, Kono Y, Rockey DC, Mehta AS Frontiers in immunology 35197973 Front Immunol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35197973
Array-Based N-Glycan Profiling of Cells in Culture. Angel PM, Mehta AS, Drake RR Methods in molecular biology (Clifton, N.J.) 33908018 Methods Mol Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33908018
Integrating age, BMI, and serum N-glycans detected by MALDI mass spectrometry to classify suspicious mammogram findings as benign lesions or breast cancer. Blaschke CRK, Hill EG, Mehta AS, Angel PM, Laronga C, Drake RR Scientific reports 36460712 Sci Rep 2022 Dec 2 https://www.ncbi.nlm.nih.gov/pubmed/36460712
Imaging Mass Spectrometry and Lectin Analysis of N-Linked Glycans in Carbohydrate Antigen-Defined Pancreatic Cancer Tissues. McDowell CT, Klamer Z, Hall J, West CA, Wisniewski L, Powers TW, Angel PM, Mehta AS, Lewin DN, Haab BB, Drake RR Molecular & cellular proteomics : MCP 33581409 Mol Cell Proteomics 2021 https://www.ncbi.nlm.nih.gov/pubmed/33581409
Optimization of Multiple Glycosidase and Chemical Stabilization Strategies for N-Glycan Isomer Detection by Mass Spectrometry Imaging in Formalin-Fixed, Paraffin-Embedded Tissues. West CA, Lu X, Grimsley G, Norris-Caneda K, Mehta AS, Angel PM, Drake RR Methods in molecular biology (Clifton, N.J.) 33908016 Methods Mol Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33908016
Evaluation of Therapeutic Collagen-Based Biomaterials in the Infarcted Mouse Heart by Extracellular Matrix Targeted MALDI Imaging Mass Spectrometry. Clift CL, McLaughlin S, Muñoz M, Suuronen EJ, Rotstein BH, Mehta AS, Drake RR, Alarcon EI, Angel PM Journal of the American Society for Mass Spectrometry 34713699 J Am Soc Mass Spectrom 2021 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/34713699
Bioorthogonal Chemical Labeling Probes Targeting Sialic Acid Isomers for N-Glycan MALDI Imaging Mass Spectrometry of Tissues, Cells, and Biofluids. Lu X, McDowell CT, Blaschke CRK, Liu L, Grimsley G, Wisniewski L, Gao C, Mehta AS, Haab BB, Angel PM, Drake RR Analytical chemistry 37126482 Anal Chem 2023 May 16 https://www.ncbi.nlm.nih.gov/pubmed/37126482
An N-glycome tissue atlas of 15 human normal and cancer tissue types determined by MALDI-imaging mass spectrometry. Wallace EN, West CA, McDowell CT, Lu X, Bruner E, Mehta AS, Aoki-Kinoshita KF, Angel PM, Drake RR Scientific reports 38177192 Sci Rep 2024 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/38177192
Multi-omic landscape of human gliomas from diagnosis to treatment and recurrence. Piyadasa H, Oberlton B, Ribi M, Ranek JS, Averbukh I, Leow K, Amouzgar M, Liu CC, Greenwald NF, McCaffrey EF, Kumar R, Ferrian S, Tsai AG, Filiz F, Fullaway CC, Bosse M, Varra SR, Kong A, Sowers C, Gephart MH, Nuñez-Perez P, Yang E, Travers M, Schachter MJ, Liang S, Santi MR, Bucktrout S, Gherardini PF, Connolly J, Cole K, Barish ME, Brown CE, Oldridge DA, Drake RR, Phillips JJ, Okada H, Prins R, Bendall SC, Angelo M bioRxiv : the preprint server for biology 40161803 bioRxiv 2025 Apr 9 https://www.ncbi.nlm.nih.gov/pubmed/40161803
The HSPG syndecan is a core organizer of cholinergic synapses. Zhou X, Vachon C, Cizeron M, Romatif O, Bülow HE, Jospin M, Bessereau JL The Journal of cell biology 34213535 J Cell Biol 2021 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/34213535
Imaging Glycosaminoglycan Modification Patterns In Vivo. Bülow HE Methods in molecular biology (Clifton, N.J.) 34626406 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/34626406
HSMotifDiscover: identification of motifs in sequences composed of non-single-letter elements. Singh VK, Misra R, Almo SC, Steidl UG, Bülow HE, Zheng D Bioinformatics (Oxford, England) 35771633 Bioinformatics 2022 Aug 10 https://www.ncbi.nlm.nih.gov/pubmed/35771633
Heparan sulfates and heparan sulfate proteoglycans in hematopoiesis. Piszczatowski RT, Bülow HE, Steidl U Blood 38639475 Blood 2024 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/38639475
Roles of glycoconjugates in neural patterning in C. elegans. Bülow HE Current topics in developmental biology 33992159 Curr Top Dev Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33992159
A glycan-based approach to cell characterization and isolation: Hematopoiesis as a paradigm. Piszczatowski RT, Schwenger E, Sundaravel S, Stein CM, Liu Y, Stanley P, Verma A, Zheng D, Seidel RD, Almo SC, Townley RA, Bülow HE, Steidl U The Journal of experimental medicine 36066492 J Exp Med 2022 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/36066492
Aurora Kinase A Inhibition: A Mega-Hit for Myelofibrosis Therapy? Piszczatowski RT, Steidl U Clinical cancer research : an official journal of the American Association for Cancer Research 31196854 Clin Cancer Res 2019 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/31196854
Who's in, who's out? Re-evaluation of lipid raft residents. Mlinac-Jerkovic K, Ilic K, Zjalić M, Mandić D, Debeljak Ž, Balog M, Damjanović V, Maček Hrvat N, Habek N, Kalanj-Bognar S, Schnaar RL, Heffer M Journal of neurochemistry 34081780 J Neurochem 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34081780
Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts. Ilic K, Lin X, Malci A, Stojanović M, Puljko B, Rožman M, Vukelić Ž, Heffer M, Montag D, Schnaar RL, Kalanj-Bognar S, Herrera-Molina R, Mlinac-Jerkovic K International journal of molecular sciences 34948386 Int J Mol Sci 2021 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/34948386
Tumor necrosis factor α receptor 1A transduces the inhibitory effect on axon regeneration triggered by IgG anti-ganglioside GD1a antibodies. Báez BB, Bacaglio CR, Prendergast JM, Rozés-Salvador V, Sheikh KA, Bianchet M, Farah MH, Schnaar RL, Bisbal M, Lopez PHH Biochimica et biophysica acta. Molecular basis of disease 38897255 Biochim Biophys Acta Mol Basis Dis 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/38897255
Ganglioside Extraction, Purification and Profiling. Porter MJ, Zhang GL, Schnaar RL Journal of visualized experiments : JoVE 33779615 J Vis Exp 2021 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/33779615
Siglec Ligands. Gonzalez-Gil A, Schnaar RL Cells 34065256 Cells 2021 May 20 https://www.ncbi.nlm.nih.gov/pubmed/34065256
The Human Ganglioside Interactome in Live Cells Revealed Using Clickable Photoaffinity Ganglioside Probes. Zhang GL, Porter MJ, Awol AK, Orsburn BC, Canner SW, Gray JJ, O'Meally RN, Cole RN, Schnaar RL Journal of the American Chemical Society 38887845 J Am Chem Soc 2024 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/38887845
Gangliosides as Siglec ligands. Schnaar RL Glycoconjugate journal 36701102 Glycoconj J 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36701102
Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3-O-sulfated heparan sulfate. Tiwari V, Tandon R, Sankaranarayanan NV, Beer JC, Kohlmeir EK, Swanson-Mungerson M, Desai UR bioRxiv : the preprint server for biology 33052337 bioRxiv 2020 Oct 8 https://www.ncbi.nlm.nih.gov/pubmed/33052337
Discovering small-molecule therapeutics against SARS-CoV-2. Tiwari V, Beer JC, Sankaranarayanan NV, Swanson-Mungerson M, Desai UR Drug discovery today 32574699 Drug Discov Today 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32574699
The alphaherpesvirus conserved pUS10 is important for natural infection and its expression is regulated by the conserved Herpesviridae protein kinase (CHPK). Ponnuraj N, Akbar H, Arrington JV, Spatz SJ, Nagarajan B, Desai UR, Jarosinski KW PLoS pathogens 36749787 PLoS Pathog 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/36749787
Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity. Morla S, Ravikumar O, O'Hara C, Boothello R, Vera A, Abdelfadiel EI, Fayyad R, Afosah DK, Sharon C, Fernandez L, Shah SA, Patel BB, Desai UR Journal of medicinal chemistry 36634271 J Med Chem 2023 Jan 26 https://www.ncbi.nlm.nih.gov/pubmed/36634271
Molecular dynamics simulations to understand glycosaminoglycan interactions in the free- and protein-bound states. Nagarajan B, Holmes SG, Sankaranarayanan NV, Desai UR Current opinion in structural biology 35306321 Curr Opin Struct Biol 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35306321
Alteration of Neuropilin-1 and Heparan Sulfate Interaction Impairs Murine B16 Tumor Growth. Painter CD, Sankaranarayanan NV, Nagarajan B, Mandel Clausen T, West AMV, Setiawan NJ, Park J, Porell RN, Bartels PL, Sandoval DR, Vasquez GJ, Chute JP, Godula K, Vander Kooi CW, Gordts PLSM, Corbett KD, Termini CM, Desai UR, Esko JD ACS chemical biology 39099090 ACS Chem Biol 2024 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/39099090
A Robust Proteomics-Based Method for Identifying Preferred Protein Targets of Synthetic Glycosaminoglycan Mimetics. Afosah DK, Ongolu R, Fayyad RM, Hawkridge A, Desai UR bioRxiv : the preprint server for biology 39896571 bioRxiv 2025 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/39896571
Structural Insights Into How Proteoglycans Determine Chemokine-CXCR1/CXCR2 Interactions: Progress and Challenges. Rajarathnam K, Desai UR Frontiers in immunology 32391006 Front Immunol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32391006
Combinatorial Virtual Library Screening Study of Transforming Growth Factor-β2-Chondroitin Sulfate System. Sankaranarayanan NV, Nagarajan B, Desai UR International journal of molecular sciences 34299163 Int J Mol Sci 2021 Jul 14 https://www.ncbi.nlm.nih.gov/pubmed/34299163
Computational studies on glycosaminoglycan recognition of sialyl transferases. Sankaranarayanan NV, Sistla S, Nagarajan B, Chittum JE, Lau JTY, Desai UR Glycobiology 37171590 Glycobiology 2023 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/37171590
Design and Synthesis of Small Molecule Probes of MDA-9/Syntenin. Sankaranarayanan NV, Villuri BK, Nagarajan B, Lewicki S, Das SK, Fisher PB, Desai UR Biomolecules 39456220 Biomolecules 2024 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/39456220
In-Depth Molecular Dynamics Study of All Possible Chondroitin Sulfate Disaccharides Reveals Key Insight into Structural Heterogeneity and Dynamism. Nagarajan B, Sankaranarayanan NV, Desai UR Biomolecules 35053225 Biomolecules 2022 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/35053225
Improving Statistical Certainty of Glycosylation Similarity between Influenza A Virus Variants Using Data-Independent Acquisition Mass Spectrometry. Chang D, Klein J, Hackett WE, Nalehua MR, Wan XF, Zaia J Molecular & cellular proteomics : MCP 36103992 Mol Cell Proteomics 2022 Nov https://www.ncbi.nlm.nih.gov/pubmed/36103992
Sequencing Heparan Sulfate Using HILIC LC-NETD-MS/MS. Wu J, Wei J, Chopra P, Boons GJ, Lin C, Zaia J Analytical chemistry 31423779 Anal Chem 2019 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/31423779
Measuring Site-specific Glycosylation Similarity between Influenza a Virus Variants with Statistical Certainty. Chang D, Hackett WE, Zhong L, Wan XF, Zaia J Molecular & cellular proteomics : MCP 32601173 Mol Cell Proteomics 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32601173
Multi-task learning sparse group lasso: a method for quantifying antigenicity of influenza A(H1N1) virus using mutations and variations in glycosylation of Hemagglutinin. Li L, Chang D, Han L, Zhang X, Zaia J, Wan XF BMC bioinformatics 32393178 BMC Bioinformatics 2020 May 11 https://www.ncbi.nlm.nih.gov/pubmed/32393178
N-glycosylation in Spodoptera frugiperda (Lepidoptera: Noctuidae) midgut membrane-bound glycoproteins. Fuzita FJ, Chandler KB, Haserick JR, Terra WR, Ferreira C, Costello CE Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 32553552 Comp Biochem Physiol B Biochem Mol Biol 2020 Aug-Sep https://www.ncbi.nlm.nih.gov/pubmed/32553552
Chemical Biology Tools for Examining the Bacterial Cell Wall. Brown AR, Gordon RA, Hyland SN, Siegrist MS, Grimes CL Cell chemical biology 32822617 Cell Chem Biol 2020 Aug 20 https://www.ncbi.nlm.nih.gov/pubmed/32822617
Membrane-partitioned cell wall synthesis in mycobacteria. García-Heredia A, Kado T, Sein CE, Puffal J, Osman SH, Judd J, Gray TA, Morita YS, Siegrist MS eLife 33544079 Elife 2021 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/33544079
Utility of bacterial peptidoglycan recycling enzymes in the chemoenzymatic synthesis of valuable UDP sugar substrates. Ukaegbu OI, DeMeester KE, Liang H, Brown AR, Jones ZS, Grimes CL Methods in enzymology 32416908 Methods Enzymol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32416908
Minimalist Tetrazine N-Acetyl Muramic Acid Probes for Rapid and Efficient Labeling of Commensal and Pathogenic Peptidoglycans in Living Bacterial Culture and During Macrophage Invasion. Hillman AS, Hyland SN, Wodzanowski KA, Moore DL, Ratna S, Jemas A, Sandles LD, Chaya T, Ghosh A, Fox JM, Grimes CL Journal of the American Chemical Society 38427023 J Am Chem Soc 2024 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/38427023
Identification and characterization of mono- and bifunctional galactan synthases in the pediatric pathogen Kingella kingae. Porsch EA, Allas MJ, Montoya NR, Muñoz VL, Tan L, Muszyński A, Azadi P, Hyland SN, Grimes CL, Kao TT, Lowary TL, St Geme JW 3rd The Journal of biological chemistry 40484378 J Biol Chem 2025 Jul https://www.ncbi.nlm.nih.gov/pubmed/40484378
Investigating Peptidoglycan Recycling Pathways in Tannerella forsythia with N-Acetylmuramic Acid Bioorthogonal Probes. Wodzanowski KA, Hyland SN, Chinthamani S, Sandles LD, Honma K, Sharma A, Grimes CL ACS infectious diseases 35924866 ACS Infect Dis 2022 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/35924866
Tools for probing host-bacteria interactions in the gut microenvironment: From molecular to cellular levels. Wodzanowski KA, Cassel SE, Grimes CL, Kloxin AM Bioorganic & medicinal chemistry letters 32223923 Bioorg Med Chem Lett 2020 May 15 https://www.ncbi.nlm.nih.gov/pubmed/32223923
Localizing Peptidoglycan Synthesis in Helicobacter pylori using Clickable Metabolic Probes. Taylor JA, Santiago CC, Gray J, Wodzanowski KA, DeMeester KE, Biboy J, Vollmer W, Grimes CL, Salama NR Current protocols 33844460 Curr Protoc 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33844460
Coupling Novel Probes with Molecular Localization Microscopy Reveals Cell Wall Homeostatic Mechanisms in Staphylococcus aureus. Lund VA, Gangotra H, Zhao Z, Sutton JAF, Wacnik K, DeMeester K, Liang H, Santiago C, Leimkuhler Grimes C, Jones S, Foster SJ ACS chemical biology 36414253 ACS Chem Biol 2022 Dec 16 https://www.ncbi.nlm.nih.gov/pubmed/36414253
DivIVA concentrates mycobacterial cell envelope assembly for initiation and stabilization of polar growth. Melzer ES, Sein CE, Chambers JJ, Siegrist MS Cytoskeleton (Hoboken, N.J.) 30160378 Cytoskeleton (Hoboken) 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30160378
A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW. Yang X, McQuillen R, Lyu Z, Phillips-Mason P, De La Cruz A, McCausland JW, Liang H, DeMeester KE, Santiago CC, Grimes CL, de Boer P, Xiao J Nature microbiology 33495624 Nat Microbiol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33495624
Metabolic Incorporation of N-Acetyl Muramic Acid Probes into Bacterial Peptidoglycan. DeMeester KE, Liang H, Zhou J, Wodzanowski KA, Prather BL, Santiago CC, Grimes CL Current protocols in chemical biology 31763799 Curr Protoc Chem Biol 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31763799
Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori. Taylor JA, Bratton BP, Sichel SR, Blair KM, Jacobs HM, DeMeester KE, Kuru E, Gray J, Biboy J, VanNieuwenhze MS, Vollmer W, Grimes CL, Shaevitz JW, Salama NR eLife 31916938 Elife 2020 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/31916938
Synthesis of Functionalized N-Acetyl Muramic Acids To Probe Bacterial Cell Wall Recycling and Biosynthesis. DeMeester KE, Liang H, Jensen MR, Jones ZS, D'Ambrosio EA, Scinto SL, Zhou J, Grimes CL Journal of the American Chemical Society 29986130 J Am Chem Soc 2018 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/29986130
Cell morphology as a virulence determinant: lessons from Helicobacter pylori. Salama NR Current opinion in microbiology 32014717 Curr Opin Microbiol 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32014717
Peptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria. García-Heredia A, Pohane AA, Melzer ES, Carr CR, Fiolek TJ, Rundell SR, Lim HC, Wagner JC, Morita YS, Swarts BM, Siegrist MS eLife 30198841 Elife 2018 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/30198841
Protected N-Acetyl Muramic Acid Probes Improve Bacterial Peptidoglycan Incorporation via Metabolic Labeling. Brown AR, Wodzanowski KA, Santiago CC, Hyland SN, Follmar JL, Asare-Okai P, Grimes CL ACS chemical biology 34506714 ACS Chem Biol 2021 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/34506714
The Legionella pneumophila peptidoglycan recycling kinase, AmgK, is essential for survival and replication inside host alveolar macrophages. Ratna S, Pradhan L, Vasconcelos MP, Acharya A, Carnahan B, Wang A, Ghosh A, Bolt A, Ellis J, Hyland SN, Hillman AS, Fox JM, Kloxin A, Neunuebel MR, Grimes CL bioRxiv : the preprint server for biology 40166355 bioRxiv 2025 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/40166355
GlycoEnzOnto: a GlycoEnzyme pathway and molecular function ontology. Groth T, Diehl AD, Gunawan R, Neelamegham S Bioinformatics (Oxford, England) 36282863 Bioinformatics 2022 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/36282863
Sweet Control: MicroRNA Regulation of the Glycome. Thu CT, Mahal LK Biochemistry 31585501 Biochemistry 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31585501
High-Throughput miRFluR Platform Identifies miRNA Regulating B3GLCT That Predict Peters' Plus Syndrome Phenotype, Supporting the miRNA Proxy Hypothesis. Thu CT, Chung JY, Dhawan D, Vaiana CA, Mahal LK ACS chemical biology 34085516 ACS Chem Biol 2021 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/34085516
microRNAs Regulate Cellular Magnesium by Tuning Expression of the Plasma Membrane Protein CNNM4. Lazarou TS, Dehghan Harati H, Mahal LK, Buccella D ACS chemical biology 40862638 ACS Chem Biol 2025 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/40862638
GAG Builder: a web-tool for modeling 3D structures of glycosaminoglycans. Singh A, Montgomery D, Xue X, Foley BL, Woods RJ Glycobiology 31034567 Glycobiology 2019 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/31034567
Induction of Antibodies Directed Against Branched Core O-Mannosyl Glycopeptides-Selectivity Complimentary to the ConA Lectin. Yu J, Grant OC, Pett C, Strahl S, Stahl S, Woods RJ, Westerlind U Chemistry (Weinheim an der Bergstrasse, Germany) 28079948 Chemistry 2017 Mar 8 https://www.ncbi.nlm.nih.gov/pubmed/28079948
Predicting the Structures of Glycans, Glycoproteins, and Their Complexes. Woods RJ Chemical reviews 30091597 Chem Rev 2018 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/30091597
Structural Rearrangements Maintain the Glycan Shield of an HIV-1 Envelope Trimer After the Loss of a Glycan. Ferreira RC, Grant OC, Moyo T, Dorfman JR, Woods RJ, Travers SA, Wood NT Scientific reports 30302011 Sci Rep 2018 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/30302011
Fluorescent Trimeric Hemagglutinins Reveal Multivalent Receptor Binding Properties. Nemanichvili N, Tomris I, Turner HL, McBride R, Grant OC, van der Woude R, Aldosari MH, Pieters RJ, Woods RJ, Paulson JC, Boons GJ, Ward AB, Verheije MH, de Vries RP Journal of molecular biology 30597163 J Mol Biol 2019 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/30597163
O-glycosylation on cerebrospinal fluid and plasma apolipoprotein E differs in the lipid-binding domain. Flowers SA, Grant OC, Woods RJ, Rebeck GW Glycobiology 31616924 Glycobiology 2020 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/31616924
Three mutations switch H7N9 influenza to human-type receptor specificity. de Vries RP, Peng W, Grant OC, Thompson AJ, Zhu X, Bouwman KM, de la Pena ATT, van Breemen MJ, Ambepitiya Wickramasinghe IN, de Haan CAM, Yu W, McBride R, Sanders RW, Woods RJ, Verheije MH, Wilson IA, Paulson JC PLoS pathogens 28617868 PLoS Pathog 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28617868
The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans. Hopper JTS, Ambrose S, Grant OC, Krumm SA, Allison TM, Degiacomi MT, Tully MD, Pritchard LK, Ozorowski G, Ward AB, Crispin M, Doores KJ, Woods RJ, Benesch JLP, Robinson CV, Struwe WB Structure (London, England : 1993) 28434916 Structure 2017 May 2 https://www.ncbi.nlm.nih.gov/pubmed/28434916
Recent H3N2 Viruses Have Evolved Specificity for Extended, Branched Human-type Receptors, Conferring Potential for Increased Avidity. Peng W, de Vries RP, Grant OC, Thompson AJ, McBride R, Tsogtbaatar B, Lee PS, Razi N, Wilson IA, Woods RJ, Paulson JC Cell host & microbe 28017661 Cell Host Microbe 2017 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/28017661
Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor. Olson LJ, Misra SK, Ishihara M, Battaile KP, Grant OC, Sood A, Woods RJ, Kim JP, Tiemeyer M, Ren G, Sharp JS, Dahms NM Communications biology 32908216 Commun Biol 2020 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/32908216
Reconciling MA'AT and molecular dynamics models of linkage conformation in oligosaccharides. Meredith RJ, Woods RJ, Carmichael I, Serianni AS Physical chemistry chemical physics : PCCP 32597425 Phys Chem Chem Phys 2020 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/32597425
A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen. Amon R, Grant OC, Leviatan Ben-Arye S, Makeneni S, Nivedha AK, Marshanski T, Norn C, Yu H, Glushka JN, Fleishman SJ, Chen X, Woods RJ, Padler-Karavani V Scientific reports 30018351 Sci Rep 2018 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/30018351
Generating 3D Models of Carbohydrates with GLYCAM-Web. Grant OC, Wentworth D, Holmes SG, Kandel R, Sehnal D, Wang X, Xiao Y, Sheppard P, Grelsson T, Coulter A, Miller G, Foley BL, Woods RJ bioRxiv : the preprint server for biology 40654779 bioRxiv 2025 May 9 https://www.ncbi.nlm.nih.gov/pubmed/40654779
GLYCAM Bacterial Carbohydrate Builder: a web-tool for modelling 3D structures of bacterial glycans. Nieto-Fabregat F, Grant OC, Wang X, Wentworth D, Woods RJ, Marchetti R bioRxiv : the preprint server for biology 41659496 bioRxiv 2026 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/41659496
Generating 3D models of complex carbohydrates with GLYCAM-Web. Grant OC, Wentworth D, Holmes SG, Kandel R, Sehnal D, Wang X, Xiao Y, Sheppard P, Grelsson T, Coulter A, Miller G, Singh A, Nagarajan M, Foley BL, Woods RJ Nature methods 41872371 Nat Methods 2026 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/41872371
Cross-Ring Fragmentation Patterns in the Tandem Mass Spectra of Underivatized Sialylated Oligosaccharides and Their Special Suitability for Spectrum Library Searching. De Leoz MLA, Simón-Manso Y, Woods RJ, Stein SE Journal of the American Society for Mass Spectrometry 30565163 J Am Soc Mass Spectrom 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30565163
Synthesis and O-Glycosidic Linkage Conformational Analysis of (13)C-Labeled Oligosaccharide Fragments of an Antifreeze Glycolipid. Zhang W, Meredith R, Yoon MK, Wang X, Woods RJ, Carmichael I, Serianni AS The Journal of organic chemistry 30624062 J Org Chem 2019 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/30624062
A Traveling Wave Ion Mobility Spectrometry (TWIMS) Study of the Robo1-Heparan Sulfate Interaction. Zhao Y, Yang JY, Thieker DF, Xu Y, Zong C, Boons GJ, Liu J, Woods RJ, Moremen KW, Amster IJ Journal of the American Society for Mass Spectrometry 29520710 J Am Soc Mass Spectrom 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29520710
O(2) sensing-associated glycosylation exposes the F-box-combining site of the Dictyostelium Skp1 subunit in E3 ubiquitin ligases. Sheikh MO, Thieker D, Chalmers G, Schafer CM, Ishihara M, Azadi P, Woods RJ, Glushka JN, Bendiak B, Prestegard JH, West CM The Journal of biological chemistry 28928219 J Biol Chem 2017 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/28928219
Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor. Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L Cell host & microbe 32841605 Cell Host Microbe 2020 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/32841605
New insights into influenza A specificity: an evolution of paradigms. Ji Y, White YJ, Hadden JA, Grant OC, Woods RJ Current opinion in structural biology 28675835 Curr Opin Struct Biol 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28675835
Structural Analysis of the Glycosylated Intact HIV-1 gp120-b12 Antibody Complex Using Hydroxyl Radical Protein Footprinting. Li X, Grant OC, Ito K, Wallace A, Wang S, Zhao P, Wells L, Lu S, Woods RJ, Sharp JS Biochemistry 28102671 Biochemistry 2017 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/28102671
Conformational Populations of β-(1→4) O-Glycosidic Linkages Using Redundant NMR J-Couplings and Circular Statistics. Zhang W, Turney T, Meredith R, Pan Q, Sernau L, Wang X, Hu X, Woods RJ, Carmichael I, Serianni AS The journal of physical chemistry. B 28296420 J Phys Chem B 2017 Apr 13 https://www.ncbi.nlm.nih.gov/pubmed/28296420
Enhanced Human-Type Receptor Binding by Ferret-Transmissible H5N1 with a K193T Mutation. Peng W, Bouwman KM, McBride R, Grant OC, Woods RJ, Verheije MH, Paulson JC, de Vries RP Journal of virology 29491160 J Virol 2018 May 15 https://www.ncbi.nlm.nih.gov/pubmed/29491160
Rapidly Display Glycan Symbols in 3D Structures: 3D-SNFG in LiteMol. Sehnal D, Grant OC Journal of proteome research 30179493 J Proteome Res 2019 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/30179493
Applying Pose Clustering and MD Simulations To Eliminate False Positives in Molecular Docking. Makeneni S, Thieker DF, Woods RJ Journal of chemical information and modeling 29431438 J Chem Inf Model 2018 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/29431438
Defining the Specificity of Carbohydrate-Protein Interactions by Quantifying Functional Group Contributions. Sood A, Gerlits OO, Ji Y, Bovin NV, Coates L, Woods RJ Journal of chemical information and modeling 30086239 J Chem Inf Model 2018 Sep 24 https://www.ncbi.nlm.nih.gov/pubmed/30086239
Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase. Thieker DF, Xu Y, Chapla D, Nora C, Qiu H, Felix T, Wang L, Moremen KW, Liu J, Esko JD, Woods RJ Scientific reports 30087361 Sci Rep 2018 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/30087361
Gly-Spec: a webtool for predicting glycan specificity by integrating glycan array screening data and 3D structure. Grant OC, Xue X, Ra D, Khatamian A, Foley BL, Woods RJ Glycobiology 28120784 Glycobiology 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/28120784
Effect of hydroxylysine-O-glycosylation on the structure of type I collagen molecule: A computational study. Tang M, Wang X, Gandhi NS, Foley BL, Burrage K, Woods RJ, Gu Y Glycobiology 32188979 Glycobiology 2020 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/32188979
Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor. Zhao P, Praissman JL, Grant OC, Cai Y, Xiao T, Rosenbalm KE, Aoki K, Kellman BP, Bridger R, Barouch DH, Brindley MA, Lewis NE, Tiemeyer M, Chen B, Woods RJ, Wells L bioRxiv : the preprint server for biology 32743578 bioRxiv 2020 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/32743578
Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition. Grant OC, Montgomery D, Ito K, Woods RJ Scientific reports 32929138 Sci Rep 2020 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/32929138
Hierarchical Multivalent Effects Control Influenza Host Specificity. Overeem NJ, Hamming PHE, Grant OC, Di Iorio D, Tieke M, Bertolino MC, Li Z, Vos G, de Vries RP, Woods RJ, Tito NB, Boons GPH, van der Vries E, Huskens J ACS central science 33376792 ACS Cent Sci 2020 Dec 23 https://www.ncbi.nlm.nih.gov/pubmed/33376792
Comparison of cellooligosaccharide conformations in complexes with proteins with energy maps for cellobiose. French AD, Montgomery DW, Prevost NT, Edwards JV, Woods RJ Carbohydrate polymers 33910736 Carbohydr Polym 2021 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/33910736
Morphology of Biomaterials Affect O-Glycosylation of HUVECs. Hu X, Sheng J, Guan G, Ju T, Smith DF, Wang L Journal of functional biomaterials 36412876 J Funct Biomater 2022 Nov 11 https://www.ncbi.nlm.nih.gov/pubmed/36412876
Synthesis and Characterization of Versatile O-Glycan Precursors for Cellular O-Glycomics. Zhang Q, Li Z, Chernova T, Saikam V, Cummings R, Song X, Ju T, Smith DF, Wang PG ACS synthetic biology 31638776 ACS Synth Biol 2019 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/31638776
Cellular O-Glycome Reporter/Amplification (CORA): Analytical and Preparative Tools to Study Mucin-Type O-Glycans of Living Cells. Kudelka MR, Li Z, Chernova TA, Smith DF, Song X, Cummings RD, Ju T Current protocols 34101390 Curr Protoc 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34101390
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia. Spiciarich DR, Oh ST, Foley A, Hughes SB, Mauro MJ, Abdel-Wahab O, Press RD, Viner R, Thompson SL, Chen Q, Azadi P, Bertozzi CR, Maxson JE Cancer research 30348809 Cancer Res 2018 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/30348809
Optimal Dissociation Methods Differ for N- and O-Glycopeptides. Riley NM, Malaker SA, Driessen MD, Bertozzi CR Journal of proteome research 32500713 J Proteome Res 2020 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/32500713
Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry. Pearsall SM, Williamson SC, Humphrey S, Hughes E, Morgan D, García Marqués FJ, Awanis G, Carroll R, Burks L, Shue YT, Bermudez A, Frese KK, Galvin M, Carter M, Priest L, Kerr A, Zhou C, Oliver TG, Humphries JD, Humphries MJ, Blackhall F, Cannell IG, Pitteri SJ, Hannon GJ, Sage J, Dive C, Simpson KL Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 37455012 J Thorac Oncol 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/37455012
A Pragmatic Guide to Enrichment Strategies for Mass Spectrometry-Based Glycoproteomics. Riley NM, Bertozzi CR, Pitteri SJ Molecular & cellular proteomics : MCP 33583771 Mol Cell Proteomics 2021 https://www.ncbi.nlm.nih.gov/pubmed/33583771
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics. Spiciarich DR, Nolley R, Maund SL, Purcell SC, Herschel J, Iavarone AT, Peehl DM, Bertozzi CR Angewandte Chemie (International ed. in English) 28649697 Angew Chem Int Ed Engl 2017 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/28649697
Development of IsoTaG, a Chemical Glycoproteomics Technique for Profiling Intact N- and O-Glycopeptides from Whole Cell Proteomes. Woo CM, Felix A, Byrd WE, Zuegel DK, Ishihara M, Azadi P, Iavarone AT, Pitteri SJ, Bertozzi CR Journal of proteome research 28244757 J Proteome Res 2017 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/28244757
Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors. Rumachik NG, Malaker SA, Poweleit N, Maynard LH, Adams CM, Leib RD, Cirolia G, Thomas D, Stamnes S, Holt K, Sinn P, May AP, Paulk NK Molecular therapy. Methods & clinical development 32995354 Mol Ther Methods Clin Dev 2020 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/32995354
O-Pair Search with MetaMorpheus for O-glycopeptide characterization. Lu L, Riley NM, Shortreed MR, Bertozzi CR, Smith LM Nature methods 33106676 Nat Methods 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/33106676
Mapping and Quantification of Over 2000 O-linked Glycopeptides in Activated Human T Cells with Isotope-Targeted Glycoproteomics (Isotag). Woo CM, Lund PJ, Huang AC, Davis MM, Bertozzi CR, Pitteri SJ Molecular & cellular proteomics : MCP 29351928 Mol Cell Proteomics 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29351928
Antibodies from Lampreys as Smart Anti-Glycan Reagents (SAGRs): Perspectives on Their Specificity, Structure, and Glyco-genomics. McKitrick TR, Eris D, Mondal N, Aryal RP, McCurley N, Heimburg-Molinaro J, Cummings RD Biochemistry 32052624 Biochemistry 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/32052624
Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Collins BC, Gunn RJ, McKitrick TR, Cummings RD, Cooper MD, Herrin BR, Wilson IA Structure (London, England : 1993) 28988747 Structure 2017 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/28988747
Development of smart anti-glycan reagents using immunized lampreys. McKitrick TR, Goth CK, Rosenberg CS, Nakahara H, Heimburg-Molinaro J, McQuillan AM, Falco R, Rivers NJ, Herrin BR, Cooper MD, Cummings RD Communications biology 32111965 Commun Biol 2020 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/32111965
Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins. McKitrick TR, Bernard SM, Noll AJ, Collins BC, Goth CK, McQuillan AM, Heimburg-Molinaro J, Herrin BR, Wilson IA, Cooper MD, Cummings RD Communications biology 34083726 Commun Biol 2021 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/34083726
Crystal structure of an anti-idiotype variable lymphocyte receptor. Collins BC, Nakahara H, Acharya S, Cooper MD, Herrin BR, Wilson IA Acta crystallographica. Section F, Structural biology communications 29199989 Acta Crystallogr F Struct Biol Commun 2017 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/29199989
Identification of Glycan-Specific Variable Lymphocyte Receptors Using Yeast Surface Display and Glycan Microarrays. McKitrick TR, Hanes MS, Rosenberg CS, Heimburg-Molinaro J, Cooper MD, Herrin BR, Cummings RD Methods in molecular biology (Clifton, N.J.) 34870812 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/34870812
Blood group O expression in normal tissues and tumors. Tulin EKC, Muerner L, McKitrick TR, Tilton CA, Pepi LE, Jia T, Noel M, Zheng LY, Stowell SR, von Gunten S, Heimburg-Molinaro J, Cummings RD The FEBS journal 40589148 FEBS J 2025 Nov https://www.ncbi.nlm.nih.gov/pubmed/40589148
VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies. Gunn RJ, Herrin BR, Acharya S, Cooper MD, Wilson IA Journal of molecular biology 29596914 J Mol Biol 2018 Apr 27 https://www.ncbi.nlm.nih.gov/pubmed/29596914
Development of lamprey-derived antibodies against human blood group antigens. Kunz PB, Tulin EKC, Mehta AY, Jia T, Heimburg-Molinaro J, Otto VI, Stowell SR, Cummings RD Glycobiology 40796252 Glycobiology 2025 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/40796252
Thyroid Carcinoma Glycoproteins Express Altered N-Glycans with 3-O-Sulfated Galactose Residues. Broekhuis JM, Lu D, Aryal RP, Matsumoto Y, Pepi LE, Chaves N, Gomez-Mayorga JL, James BC, Cummings RD Biomolecules 39766189 Biomolecules 2024 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/39766189
Development and applications of sialoglycan-recognizing probes (SGRPs) with defined specificities: exploring the dynamic mammalian sialoglycome. Srivastava S, Verhagen A, Sasmal A, Wasik BR, Diaz S, Yu H, Bensing BA, Khan N, Khedri Z, Secrest P, Sullam P, Varki N, Chen X, Parrish CR, Varki A Glycobiology 35926090 Glycobiology 2022 Nov 22 https://www.ncbi.nlm.nih.gov/pubmed/35926090
An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism. Song H, Qi J, Khedri Z, Diaz S, Yu H, Chen X, Varki A, Shi Y, Gao GF PLoS pathogens 26816272 PLoS Pathog 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/26816272
Effective one-pot multienzyme (OPME) synthesis of monotreme milk oligosaccharides and other sialosides containing 4-O-acetyl sialic acid. Yu H, Zeng J, Li Y, Thon V, Shi B, Chen X Organic & biomolecular chemistry 27548611 Org Biomol Chem 2016 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/27548611
Biological roles of glycans. Varki A Glycobiology 27558841 Glycobiology 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27558841
Distribution of O-Acetylated Sialic Acids among Target Host Tissues for Influenza Virus. Wasik BR, Barnard KN, Ossiboff RJ, Khedri Z, Feng KH, Yu H, Chen X, Perez DR, Varki A, Parrish CR mSphere 28904995 mSphere 2017 Sep-Oct https://www.ncbi.nlm.nih.gov/pubmed/28904995
Novel aspects of sialoglycan recognition by the Siglec-like domains of streptococcal SRR glycoproteins. Bensing BA, Khedri Z, Deng L, Yu H, Prakobphol A, Fisher SJ, Chen X, Iverson TM, Varki A, Sullam PM Glycobiology 27037304 Glycobiology 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27037304
The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. Nguyen T, Lee S, Yang YA, Ahn C, Sim JH, Kei TG, Barnard KN, Yu H, Millano SK, Chen X, Parrish CR, Song J PLoS pathogens 32084237 PLoS Pathog 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/32084237
Effects of Sialic Acid Modifications on Virus Binding and Infection. Wasik BR, Barnard KN, Parrish CR Trends in microbiology 27491885 Trends Microbiol 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27491885
Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins. Langereis MA, Bakkers MJ, Deng L, Padler-Karavani V, Vervoort SJ, Hulswit RJ, van Vliet AL, Gerwig GJ, de Poot SA, Boot W, van Ederen AM, Heesters BA, van der Loos CM, van Kuppeveld FJ, Yu H, Huizinga EG, Chen X, Varki A, Kamerling JP, de Groot RJ Cell reports 26095364 Cell Rep 2015 Jun 30 https://www.ncbi.nlm.nih.gov/pubmed/26095364
Symbol Nomenclature for Graphical Representations of Glycans. Varki A, Cummings RD, Aebi M, Packer NH, Seeberger PH, Esko JD, Stanley P, Hart G, Darvill A, Kinoshita T, Prestegard JJ, Schnaar RL, Freeze HH, Marth JD, Bertozzi CR, Etzler ME, Frank M, Vliegenthart JF, Lütteke T, Perez S, Bolton E, Rudd P, Paulson J, Kanehisa M, Toukach P, Aoki-Kinoshita KF, Dell A, Narimatsu H, York W, Taniguchi N, Kornfeld S Glycobiology 26543186 Glycobiology 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26543186
Pre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein. Joo EJ, Wasik BR, Parrish C, Paz H, Mϋhlenhoff M, Abdel-Azim H, Groffen J, Heisterkamp N Scientific reports 30464179 Sci Rep 2018 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/30464179
Expression of 9-O- and 7,9-O-Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses. Barnard KN, Wasik BR, LaClair JR, Buchholz DW, Weichert WS, Alford-Lawrence BK, Aguilar HC, Parrish CR mBio 31796537 mBio 2019 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/31796537
Glycosaminoglycans from fish swim bladder: isolation, structural characterization and bioactive potential. Pan Y, Wang P, Zhang F, Yu Y, Zhang X, Lin L, Linhardt RJ Glycoconjugate journal 29124565 Glycoconj J 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29124565
Construction and functional characterization of truncated versions of recombinant keratanase II from Bacillus circulans. Wang H, He W, Jiang P, Yu Y, Lin L, Sun X, Koffas M, Zhang F, Linhardt RJ Glycoconjugate journal 28752383 Glycoconj J 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28752383
Sequencing the Dermatan Sulfate Chain of Decorin. Yu Y, Duan J, Leach FE 3rd, Toida T, Higashi K, Zhang H, Zhang F, Amster IJ, Linhardt RJ Journal of the American Chemical Society 29111696 J Am Chem Soc 2017 Nov 22 https://www.ncbi.nlm.nih.gov/pubmed/29111696
Negative Electron Transfer Dissociation Sequencing of Increasingly Sulfated Glycosaminoglycan Oligosaccharides on an Orbitrap Mass Spectrometer. Leach FE 3rd, Riley NM, Westphall MS, Coon JJ, Amster IJ Journal of the American Society for Mass Spectrometry 28589488 J Am Soc Mass Spectrom 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/28589488
Analysis of heparin oligosaccharides by capillary electrophoresis-negative-ion electrospray ionization mass spectrometry. Lin L, Liu X, Zhang F, Chi L, Amster IJ, Leach FE 3rd, Xia Q, Linhardt RJ Analytical and bioanalytical chemistry 27325464 Anal Bioanal Chem 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27325464
Glycosaminoglycans from bovine eye vitreous humour and interaction with collagen type II. Peng Y, Yu Y, Lin L, Liu X, Zhang X, Wang P, Hoffman P, Kim SY, Zhang F, Linhardt RJ Glycoconjugate journal 29305777 Glycoconj J 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29305777
Borrelia burgdorferi glycosaminoglycan-binding proteins: a potential target for new therapeutics against Lyme disease. Lin YP, Li L, Zhang F, Linhardt RJ Microbiology (Reading, England) 29116038 Microbiology (Reading) 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/29116038
Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission. Hart T, Nguyen NTT, Nowak NA, Zhang F, Linhardt RJ, Diuk-Wasser M, Ram S, Kraiczy P, Lin YP PLoS pathogens 29813137 PLoS Pathog 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29813137
Oligosaccharide substrate preferences of human extracellular sulfatase Sulf2 using liquid chromatography-mass spectrometry based glycomics approaches. Huang Y, Mao Y, Buczek-Thomas JA, Nugent MA, Zaia J PloS one 25127119 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/25127119
Discovery of a heparan sulfate 3-O-sulfation specific peeling reaction. Huang Y, Mao Y, Zong C, Lin C, Boons GJ, Zaia J Analytical chemistry 25486437 Anal Chem 2015 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/25486437
A liquid chromatography-mass spectrometry-based approach to characterize the substrate specificity of mammalian heparanase. Mao Y, Huang Y, Buczek-Thomas JA, Ethen CM, Nugent MA, Wu ZL, Zaia J The Journal of biological chemistry 25336655 J Biol Chem 2014 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/25336655
Complete Molecular Weight Profiling of Low-Molecular Weight Heparins Using Size Exclusion Chromatography-Ion Suppressor-High-Resolution Mass Spectrometry. Zaia J, Khatri K, Klein J, Shao C, Sheng Y, Viner R Analytical chemistry 27709905 Anal Chem 2016 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/27709905
A computational framework for heparan sulfate sequencing using high-resolution tandem mass spectra. Hu H, Huang Y, Mao Y, Yu X, Xu Y, Liu J, Zong C, Boons GJ, Lin C, Xia Y, Zaia J Molecular & cellular proteomics : MCP 24925905 Mol Cell Proteomics 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/24925905
Imaging specific cellular glycan structures using glycosyltransferases via click chemistry. Wu ZL, Person AD, Anderson M, Burroughs B, Tatge T, Khatri K, Zou Y, Wang L, Geders T, Zaia J, Sackstein R Glycobiology 29186441 Glycobiology 2018 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/29186441
X-Ray Induced Photodynamic Therapy: A Combination of Radiotherapy and Photodynamic Therapy. Wang GD, Nguyen HT, Chen H, Cox PB, Wang L, Nagata K, Hao Z, Wang A, Li Z, Xie J Theranostics 27877235 Theranostics 2016 https://www.ncbi.nlm.nih.gov/pubmed/27877235
Heparan Sulfate Microarray Reveals That Heparan Sulfate-Protein Binding Exhibits Different Ligand Requirements. Zong C, Venot A, Li X, Lu W, Xiao W, Wilkes JL, Salanga CL, Handel TM, Wang L, Wolfert MA, Boons GJ Journal of the American Chemical Society 28651046 J Am Chem Soc 2017 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/28651046
Proteomic Profiling Exosomes from Vascular Smooth Muscle Cell. Qiu H, Shi S, Wang S, Peng H, Ding SJ, Wang L Proteomics. Clinical applications 29687628 Proteomics Clin Appl 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/29687628
Endothelial heparan sulfate deficiency reduces inflammation and fibrosis in murine diabetic nephropathy. Talsma DT, Katta K, Ettema MAB, Kel B, Kusche-Gullberg M, Daha MR, Stegeman CA, van den Born J, Wang L Laboratory investigation; a journal of technical methods and pathology 29330473 Lab Invest 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29330473
Application of a Mutant Cell Library to Determine the Structure-Function Relationship of Heparan Sulfate in Facilitating FGF2-FGFR1 Signaling. Faulkner J, Song X, Wang L Methods in molecular biology (Clifton, N.J.) 34626412 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/34626412
Label-Free and Continuous-Flow Ferrohydrodynamic Separation of HeLa Cells and Blood Cells in Biocompatible Ferrofluids. Zhao W, Zhu T, Cheng R, Liu Y, He J, Qiu H, Wang L, Nagy T, Querec TD, Unger ER, Mao L Advanced functional materials 27478429 Adv Funct Mater 2016 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/27478429
A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships. Qiu H, Shi S, Yue J, Xin M, Nairn AV, Lin L, Liu X, Li G, Archer-Hartmann SA, Dela Rosa M, Galizzi M, Wang S, Zhang F, Azadi P, van Kuppevelt TH, Cardoso WV, Kimata K, Ai X, Moremen KW, Esko JD, Linhardt RJ, Wang L Nature methods 30377379 Nat Methods 2018 Nov https://www.ncbi.nlm.nih.gov/pubmed/30377379
Integrated Approach to Identify Heparan Sulfate Ligand Requirements of Robo1. Zong C, Huang R, Condac E, Chiu Y, Xiao W, Li X, Lu W, Ishihara M, Wang S, Ramiah A, Stickney M, Azadi P, Amster IJ, Moremen KW, Wang L, Sharp JS, Boons GJ Journal of the American Chemical Society 27611601 J Am Chem Soc 2016 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/27611601
High-resolution probing heparan sulfate-antithrombin interaction on a single endothelial cell surface: single-molecule AFM studies. Guo C, Fan X, Qiu H, Xiao W, Wang L, Xu B Physical chemistry chemical physics : PCCP 25921251 Phys Chem Chem Phys 2015 May 28 https://www.ncbi.nlm.nih.gov/pubmed/25921251
Gated Trapped Ion Mobility Spectrometry Coupled to Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Ridgeway ME, Wolff JJ, Silveira JA, Lin C, Costello CE, Park MA International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry 27667964 Int J Ion Mobil Spectrom 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/27667964
De Novo Glycan Sequencing by Electronic Excitation Dissociation and Fixed-Charge Derivatization. Tang Y, Pu Y, Gao J, Hong P, Costello CE, Lin C Analytical chemistry 29443510 Anal Chem 2018 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/29443510
Accurate Identification of Isomeric Glycans by Trapped Ion Mobility Spectrometry-Electronic Excitation Dissociation Tandem Mass Spectrometry. Wei J, Tang Y, Ridgeway ME, Park MA, Costello CE, Lin C Analytical chemistry 32865981 Anal Chem 2020 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/32865981
GlycoDeNovo - an Efficient Algorithm for Accurate de novo Glycan Topology Reconstruction from Tandem Mass Spectra. Hong P, Sun H, Sha L, Pu Y, Khatri K, Yu X, Tang Y, Lin C Journal of the American Society for Mass Spectrometry 28786094 J Am Soc Mass Spectrom 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28786094
Identification of Sialic Acid Linkages on Intact Glycopeptides via Differential Chemical Modification Using IntactGIG-HILIC. Yang S, Wu WW, Shen RF, Bern M, Cipollo J Journal of the American Society for Mass Spectrometry 29651731 J Am Soc Mass Spectrom 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29651731
Differential Quantitative Determination of Site-Specific Intact N-Glycopeptides in Serum Haptoglobin between Hepatocellular Carcinoma and Cirrhosis Using LC-EThcD-MS/MS. Zhu J, Chen Z, Zhang J, An M, Wu J, Yu Q, Skilton SJ, Bern M, Ilker Sen K, Li L, Lubman DM Journal of proteome research 30370771 J Proteome Res 2019 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/30370771
Tool for Rapid Analysis of Glycopeptide by Permethylation via One-Pot Site Mapping and Glycan Analysis. Shajahan A, Supekar NT, Heiss C, Ishihara M, Azadi P Analytical chemistry 28921966 Anal Chem 2017 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/28921966
High-Throughput Automated Micro-permethylation for Glycan Structure Analysis. Shajahan A, Supekar N, Heiss C, Azadi P Analytical chemistry 30572707 Anal Chem 2019 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/30572707
Glycomic and glycoproteomic analysis of glycoproteins-a tutorial. Shajahan A, Heiss C, Ishihara M, Azadi P Analytical and bioanalytical chemistry 28585084 Anal Bioanal Chem 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28585084
Mass Spectrometric Method for the Unambiguous Profiling of Cellular Dynamic Glycosylation. Shajahan A, Supekar NT, Wu H, Wands AM, Bhat G, Kalimurthy A, Matsubara M, Ranzinger R, Kohler JJ, Azadi P ACS chemical biology 32809798 ACS Chem Biol 2020 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/32809798
A map of the phosphoproteomic alterations that occur after a bout of maximal-intensity contractions. Potts GK, McNally RM, Blanco R, You JS, Hebert AS, Westphall MS, Coon JJ, Hornberger TA The Journal of physiology 28542873 J Physiol 2017 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/28542873
Full-Featured Search Algorithm for Negative Electron-Transfer Dissociation. Riley NM, Bern M, Westphall MS, Coon JJ Journal of proteome research 27402189 J Proteome Res 2016 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/27402189
Sequencing Larger Intact Proteins (30-70 kDa) with Activated Ion Electron Transfer Dissociation. Riley NM, Westphall MS, Coon JJ Journal of the American Society for Mass Spectrometry 29027149 J Am Soc Mass Spectrom 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29027149
Activated Ion-Electron Transfer Dissociation Enables Comprehensive Top-Down Protein Fragmentation. Riley NM, Westphall MS, Coon JJ Journal of proteome research 28608681 J Proteome Res 2017 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/28608681
A graphical representation of glycan heterogeneity. Zeng X, Novotny MV, Clemmer DE, Trinidad JC Glycobiology 34939082 Glycobiology 2022 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/34939082
Development of capillary liquid chromatography: A personal perspective. Novotny MV Journal of chromatography. A 28701267 J Chromatogr A 2017 Nov 10 https://www.ncbi.nlm.nih.gov/pubmed/28701267
Comprehensive Analytical Approach toward Glycomic Characterization and Profiling in Urinary Exosomes. Zou G, Benktander JD, Gizaw ST, Gaunitz S, Novotny MV Analytical chemistry 28402650 Anal Chem 2017 May 16 https://www.ncbi.nlm.nih.gov/pubmed/28402650
Analytical Scheme Leading to Integrated High-Sensitivity Profiling of Glycosphingolipids Together with N- and O-Glycans from One Sample. Benktander JD, Gizaw ST, Gaunitz S, Novotny MV Journal of the American Society for Mass Spectrometry 29744812 J Am Soc Mass Spectrom 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29744812
Highly Sensitive O-Glycan Profiling for Human Serum Proteins Reveals Gender-Dependent Changes in Colorectal Cancer Patients. Gizaw ST, Gaunitz S, Novotny MV Analytical chemistry 30983323 Anal Chem 2019 May 7 https://www.ncbi.nlm.nih.gov/pubmed/30983323
Flexible Linker Modulates Glycosaminoglycan Affinity of Decorin Binding Protein A. Morgan A, Sepuru KM, Feng W, Rajarathnam K, Wang X Biochemistry 26223367 Biochemistry 2015 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/26223367
Structural studies reveal an important role for the pleiotrophin C-terminus in mediating interactions with chondroitin sulfate. Ryan E, Shen D, Wang X The FEBS journal 26896299 FEBS J 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26896299
Structure of decorin binding protein B from Borrelia burgdorferi and its interactions with glycosaminoglycans. Feng W, Wang X Biochimica et biophysica acta 26275806 Biochim Biophys Acta 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26275806
Pleiotrophin, a multifunctional cytokine and growth factor, induces leukocyte responses through the integrin Mac-1. Shen D, Podolnikova NP, Yakubenko VP, Ardell CL, Balabiyev A, Ugarova TP, Wang X The Journal of biological chemistry 28939773 J Biol Chem 2017 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/28939773
Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling. Im J, Biswas S, Liu H, Zhao Y, Sen S, Biswas S, Ashcroft B, Borges C, Wang X, Lindsay S, Zhang P Nature communications 28000682 Nat Commun 2016 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/28000682
Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells. Schumann B, Malaker SA, Wisnovsky SP, Debets MF, Agbay AJ, Fernandez D, Wagner LJS, Lin L, Li Z, Choi J, Fox DM, Peh J, Gray MA, Pedram K, Kohler JJ, Mrksich M, Bertozzi CR Molecular cell 32325029 Mol Cell 2020 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/32325029
Photocrosslinking probes for capture of carbohydrate interactions. Wu H, Kohler J Current opinion in chemical biology 31706134 Curr Opin Chem Biol 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31706134
Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells. Calle B, Gonzalez-Rodriguez E, Mahoney KE, Cioce A, Bineva-Todd G, Tastan OY, Roustan C, Flynn H, Malaker SA, Schumann B STAR protocols 36633947 STAR Protoc 2023 Mar 17 https://www.ncbi.nlm.nih.gov/pubmed/36633947
Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Toleman CA, Schumacher MA, Yu SH, Zeng W, Cox NJ, Smith TJ, Soderblom EJ, Wands AM, Kohler JJ, Boyce M Proceedings of the National Academy of Sciences of the United States of America 29784830 Proc Natl Acad Sci U S A 2018 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/29784830
A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis. Park SK, Zhou X, Pendleton KE, Hunter OV, Kohler JJ, O'Donnell KA, Conrad NK Cell reports 28768194 Cell Rep 2017 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/28768194
O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis. Taparra K, Wang H, Malek R, Lafargue A, Barbhuiya MA, Wang X, Simons BW, Ballew M, Nugent K, Groves J, Williams RD, Shiraishi T, Verdone J, Yildirir G, Henry R, Zhang B, Wong J, Wang KK, Nelkin BD, Pienta KJ, Felsher D, Zachara NE, Tran PT The Journal of clinical investigation 30130254 J Clin Invest 2018 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/30130254
Molecular Functions of Glycoconjugates in Autophagy. Fahie K, Zachara NE Journal of molecular biology 27345664 J Mol Biol 2016 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/27345664

This page last reviewed on April 13, 2026

Scroll To Top