Part of the Common Fund's High-Risk, High-Reward Research program, the NIH Director's Transformative Research Award supports exceptionally innovative, unconventional, paradigm-shifting research projects that are inherently risky and untested.
New Technique Blasts Circulating Cancer Cells in the Blood
Lihong Wang, a 2012 Pioneer and 2013 Transformative Researcher, developed lasers that can detect and target cancerous melanoma cells circulating in the blood and vaporize them without harming surrounding tissue. The technique may be useful in preventing the spread of cancer throughout the body.
Visualizing RNA using Expansion Microscopy
Arjun Raj (a 2011 New Innovator) and Edward Boyden (a 2007 New Innovator, 2012 and 2013 Transformative Researcher, and 2013 Pioneer) describe a new technique that can image RNA in cells and tissue by using “expansion microscopy,” a method where samples are physically enlarged with an expandable polymer, making high resolution imaging possible with common laboratory microscopes.
The Office of the Director in partnership with
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- National Cancer Institute
- National Center for Complementary and Integrative Health
- National Heart, Lung, and Blood Institute
- National Human Genome Research Institute
- National Institute of Allergy and Infectious Diseases
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- National Institute of Biomedical Imaging and Bioengineering
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute of Environmental Health Sciences
- National Institute of General Medical Sciences
- National Institute of Mental Health
- National Institute of Neurological Disorders and Stroke
- National Institute on Aging