Program Publications
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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
Title | Author | Journal Name | PubMedID | Journal Abbreviation | Publication Date | PubMedLink |
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Exploring Antibiotic Resistance in Diverse Homologs of the Dihydrofolate Reductase Protein Family through Broad Mutational Scanning. | Romanowicz KJ, Resnick C, Hinton SR, Plesa C | bioRxiv : the preprint server for biology | 39896582 | bioRxiv | 2025 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/39896582 |
Rational Design of Nanomedicine for Placental Disorders: Birthing a New Era in Women's Reproductive Health. | Geisler HC, Safford HC, Mitchell MJ | Small (Weinheim an der Bergstrasse, Germany) | 37191231 | Small | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37191231 |
Peptide functionalized liposomes for receptor targeted cancer therapy. | Aronson MR, Medina SH, Mitchell MJ | APL bioengineering | 33532673 | APL Bioeng | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33532673 |
An ionizable lipid toolbox for RNA delivery. | Han X, Zhang H, Butowska K, Swingle KL, Alameh MG, Weissman D, Mitchell MJ | Nature communications | 34903741 | Nat Commun | 2021 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/34903741 |
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. | Gong N, Han X, Xue L, Billingsley MM, Huang X, El-Mayta R, Qin J, Sheppard NC, June CH, Mitchell MJ | Nature biomedical engineering | 38378820 | Nat Biomed Eng | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38378820 |
Lipid-mediated intracellular delivery of recombinant bioPROTACs for the rapid degradation of undruggable proteins. | Chan A, Haley RM, Najar MA, Gonzalez-Martinez D, Bugaj LJ, Burslem GM, Mitchell MJ, Tsourkas A | Nature communications | 38987546 | Nat Commun | 2024 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/38987546 |
Flow cytometric analysis of the murine placenta to evaluate nanoparticle platforms during pregnancy. | Swingle KL, Hamilton AG, Mitchell MJ | Placenta | 39181830 | Placenta | 2024 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/39181830 |
Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain. | Nong J, Glassman PM, Myerson JW, Zuluaga-Ramirez V, Rodriguez-Garcia A, Mukalel A, Omo-Lamai S, Walsh LR, Zamora ME, Gong X, Wang Z, Bhamidipati K, Kiseleva RY, Villa CH, Greineder CF, Kasner SE, Weissman D, Mitchell MJ, Muro S, Persidsky Y, Brenner JS, Muzykantov VR, Marcos-Contreras OA | ACS nano | 37432926 | ACS Nano | 2023 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/37432926 |
Solution biophysics identifies lipid nanoparticle non-sphericity, polydispersity, and dependence on internal ordering for efficacious mRNA delivery. | Padilla MS, Shepherd SJ, Hanna AR, Kurnik M, Zhang X, Chen M, Byrnes J, Joseph RA, Yamagata HM, Ricciardi AS, Mrksich K, Issadore D, Gupta K, Mitchell MJ | bioRxiv : the preprint server for biology | 39763759 | bioRxiv | 2025 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/39763759 |
Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes. | Guimaraes PPG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CTR, Jacks T, Langer R, Mitchell MJ | Journal of controlled release : official journal of the Controlled Release Society | 30290244 | J Control Release | 2018 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/30290244 |
Chiral Supraparticles for Controllable Nanomedicine. | Yeom J, Guimaraes PPG, Ahn HM, Jung BK, Hu Q, McHugh K, Mitchell MJ, Yun CO, Langer R, Jaklenec A | Advanced materials (Deerfield Beach, Fla.) | 31686433 | Adv Mater | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31686433 |
Ionizable lipid nanoparticles for in utero mRNA delivery. | Riley RS, Kashyap MV, Billingsley MM, White B, Alameh MG, Bose SK, Zoltick PW, Li H, Zhang R, Cheng AY, Weissman D, Peranteau WH, Mitchell MJ | Science advances | 33523869 | Sci Adv | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33523869 |
Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver. | Zhang R , El-Mayta R , Murdoch TJ , Warzecha CC , Billingsley MM , Shepherd SJ , Gong N , Wang L , Wilson JM , Lee D , Mitchell MJ | Biomaterials science | 33404020 | Biomater Sci | 2021 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/33404020 |
Nanomaterials for T-cell cancer immunotherapy. | Gong N, Sheppard NC, Billingsley MM, June CH, Mitchell MJ | Nature nanotechnology | 33437036 | Nat Nanotechnol | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33437036 |
Engineering precision nanoparticles for drug delivery. | Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R | Nature reviews. Drug discovery | 33277608 | Nat Rev Drug Discov | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33277608 |
Cytosolic Delivery of Small Protein Scaffolds Enables Efficient Inhibition of Ras and Myc. | Chan A, Wang HH, Haley RM, Song C, Gonzalez-Martinez D, Bugaj L, Mitchell MJ, Tsourkas A | Molecular pharmaceutics | 35225618 | Mol Pharm | 2022 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/35225618 |
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells. | Patel SK, Billingsley MM, Frazee C, Han X, Swingle KL, Qin J, Alameh MG, Wang K, Weissman D, Mitchell MJ | Journal of controlled release : official journal of the Controlled Release Society | 35569584 | J Control Release | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35569584 |
Piperazine-Derived Bisphosphonate-Based Ionizable Lipid Nanoparticles Enhance mRNA Delivery to the Bone Microenvironment. | Yoon IC, Xue L, Chen Q, Liu J, Xu J, Siddiqui Z, Kim D, Chen B, Shi Q, Laura Han E, Cherry Ruiz M, Vining KH, Mitchell MJ | Angewandte Chemie (International ed. in English) | 39379320 | Angew Chem Int Ed Engl | 2025 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/39379320 |
Rational design of anti-inflammatory lipid nanoparticles for mRNA delivery. | Zhang H, Han X, Alameh MG, Shepherd SJ, Padilla MS, Xue L, Butowska K, Weissman D, Mitchell MJ | Journal of biomedical materials research. Part A | 35076171 | J Biomed Mater Res A | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35076171 |
In vivo bone marrow microenvironment siRNA delivery using lipid-polymer nanoparticles for multiple myeloma therapy. | Guimarães PPG, Figueroa-Espada CG, Riley RS, Gong N, Xue L, Sewastianik T, Dennis PS, Loebel C, Chung A, Shepherd SJ, Haley RM, Hamilton AG, El-Mayta R, Wang K, Langer R, Anderson DG, Carrasco RD, Mitchell MJ | Proceedings of the National Academy of Sciences of the United States of America | 37310997 | Proc Natl Acad Sci U S A | 2023 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/37310997 |
siRNA Lipid-Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy. | Figueroa-Espada CG, Guimarães PPG, Riley RS, Xue L, Wang K, Mitchell MJ | Cellular and molecular bioengineering | 37810998 | Cell Mol Bioeng | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37810998 |
Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta. | Safford HC, Swingle KL, Geisler HC, Hamilton AG, Thatte AS, Ghalsasi AA, Billingsley MM, Alameh MG, Weissman D, Mitchell MJ | Small (Weinheim an der Bergstrasse, Germany) | 37537704 | Small | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37537704 |
Nanoparticle protein corona: from structure and function to therapeutic targeting. | Bashiri G, Padilla MS, Swingle KL, Shepherd SJ, Mitchell MJ, Wang K | Lab on a chip | 36655824 | Lab Chip | 2023 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/36655824 |
Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy. | Metzloff AE, Padilla MS, Gong N, Billingsley MM, Han X, Merolle M, Mai D, Figueroa-Espada CG, Thatte AS, Haley RM, Mukalel AJ, Hamilton AG, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ | Advanced materials (Deerfield Beach, Fla.) | 38419362 | Adv Mater | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38419362 |
In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells. | Palanki R, Riley JS, Bose SK, Luks V, Dave A, Kus N, White BM, Ricciardi AS, Swingle KL, Xue L, Sung D, Thatte AS, Safford HC, Chaluvadi VS, Carpenter M, Han EL, Maganti R, Hamilton AG, Mrksich K, Billingsley MB, Zoltick PW, Alameh MG, Weissman D, Mitchell MJ, Peranteau WH | Proceedings of the National Academy of Sciences of the United States of America | 39078677 | Proc Natl Acad Sci U S A | 2024 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/39078677 |
Optimized microfluidic formulation and organic excipients for improved lipid nanoparticle mediated genome editing. | Palanki R, Han EL, Murray AM, Maganti R, Tang S, Swingle KL, Kim D, Yamagata H, Safford HC, Mrksich K, Peranteau WH, Mitchell MJ | Lab on a chip | 39037068 | Lab Chip | 2024 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/39037068 |
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo. | Han X, Alameh MG, Gong N, Xue L, Ghattas M, Bojja G, Xu J, Zhao G, Warzecha CC, Padilla MS, El-Mayta R, Dwivedi G, Xu Y, Vaughan AE, Wilson JM, Weissman D, Mitchell MJ | Nature chemistry | 38982196 | Nat Chem | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38982196 |
Breaking the final barrier: Evolution of cationic and ionizable lipid structure in lipid nanoparticles to escape the endosome. | Mrksich K, Padilla MS, Mitchell MJ | Advanced drug delivery reviews | 39293650 | Adv Drug Deliv Rev | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39293650 |
Peptide-functionalized nanoparticles for brain-targeted therapeutics. | Tang S, Han EL, Mitchell MJ | Drug delivery and translational research | 40164912 | Drug Deliv Transl Res | 2025 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/40164912 |
Microfluidic formulation of nanoparticles for biomedical applications. | Shepherd SJ, Issadore D, Mitchell MJ | Biomaterials | 33965797 | Biomaterials | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33965797 |
Nanomaterial Interactions with Human Neutrophils. | Bisso PW, Gaglione S, Guimarães PPG, Mitchell MJ, Langer R | ACS biomaterials science & engineering | 31497639 | ACS Biomater Sci Eng | 2018 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/31497639 |
Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening. | Guimaraes PPG, Zhang R, Spektor R, Tan M, Chung A, Billingsley MM, El-Mayta R, Riley RS, Wang L, Wilson JM, Mitchell MJ | Journal of controlled release : official journal of the Controlled Release Society | 31678653 | J Control Release | 2019 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/31678653 |
Cyclodextrins in drug delivery: applications in gene and combination therapy. | Haley RM, Gottardi R, Langer R, Mitchell MJ | Drug delivery and translational research | 32077052 | Drug Deliv Transl Res | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32077052 |
Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering. | Billingsley MM, Singh N, Ravikumar P, Zhang R, June CH, Mitchell MJ | Nano letters | 31951421 | Nano Lett | 2020 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/31951421 |
Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. | Zhao G, Xue L, Geisler HC, Xu J, Li X, Mitchell MJ, Vaughan AE | Proceedings of the National Academy of Sciences of the United States of America | 38315853 | Proc Natl Acad Sci U S A | 2024 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/38315853 |
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery. | Patel SK, Billingsley MM, Mukalel AJ, Thatte AS, Hamilton AG, Gong N, El-Mayta R, Safford HC, Merolle M, Mitchell MJ | Theranostics | 38164140 | Theranostics | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38164140 |
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism. | Billingsley MM, Gong N, Mukalel AJ, Thatte AS, El-Mayta R, Patel SK, Metzloff AE, Swingle KL, Han X, Xue L, Hamilton AG, Safford HC, Alameh MG, Papp TE, Parhiz H, Weissman D, Mitchell MJ | Small (Weinheim an der Bergstrasse, Germany) | 38072809 | Small | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38072809 |
Emerging strategies for nanomedicine in autoimmunity. | Thatte AS, Billingsley MM, Weissman D, Melamed JR, Mitchell MJ | Advanced drug delivery reviews | 38342243 | Adv Drug Deliv Rev | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38342243 |
Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device. | Shepherd SJ, Warzecha CC, Yadavali S, El-Mayta R, Alameh MG, Wang L, Weissman D, Wilson JM, Issadore D, Mitchell MJ | Nano letters | 34189917 | Nano Lett | 2021 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/34189917 |
Nanotechnology-based strategies against SARS-CoV-2 variants. | Huang X, Kon E, Han X, Zhang X, Kong N, Mitchell MJ, Peer D, Tao W | Nature nanotechnology | 35982317 | Nat Nanotechnol | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/35982317 |
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity. | Zhong W, Lu Y, Han X, Yang J, Qin Z, Zhang W, Yu Z, Wu B, Liu S, Xu W, Zheng C, Schuchter LM, Karakousis GC, Mitchell TC, Amaravadi R, Flowers AJ, Gimotty PA, Xiao M, Mills G, Herlyn M, Dong H, Mitchell MJ, Kim J, Xu X, Guo W | Cell reports | 37805922 | Cell Rep | 2023 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/37805922 |
Lipid Nanoparticle Delivery of Small Proteins for Potent In Vivo RAS Inhibition. | Haley RM, Chan A, Billingsley MM, Gong N, Padilla MS, Kim EH, Wang H, Yin D, Wangensteen KJ, Tsourkas A, Mitchell MJ | ACS applied materials & interfaces | 37115558 | ACS Appl Mater Interfaces | 2023 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/37115558 |
Ionizable lipid nanoparticles for RAS protease delivery to inhibit cancer cell proliferation. | Atsavapranee E, Haley RM, Billingsley MM, Chan A, Ruan B, Figueroa-Espada CG, Gong N, Mukalel AJ, Bryan PN, Mitchell MJ | Journal of controlled release : official journal of the Controlled Release Society | 38729436 | J Control Release | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38729436 |
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. | Xue L, Hamilton AG, Zhao G, Xiao Z, El-Mayta R, Han X, Gong N, Xiong X, Xu J, Figueroa-Espada CG, Shepherd SJ, Mukalel AJ, Alameh MG, Cui J, Wang K, Vaughan AE, Weissman D, Mitchell MJ | Nature communications | 38424061 | Nat Commun | 2024 Feb 29 | https://www.ncbi.nlm.nih.gov/pubmed/38424061 |
Lipid nanoparticle-mediated RNA delivery for immune cell modulation. | Kim EH, Teerdhala SV, Padilla MS, Joseph RA, Li JJ, Haley RM, Mitchell MJ | European journal of immunology | 39279550 | Eur J Immunol | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39279550 |
Plug-and-play assembly of biodegradable ionizable lipids for potent mRNA delivery and gene editing in vivo. | Han X, Xu Y, Ricciardi A, Xu J, Palanki R, Chowdhary V, Xue L, Gong N, Alameh MG, Peranteau WH, Wilson JM, Weissman D, Mitchell MJ | bioRxiv : the preprint server for biology | 40060499 | bioRxiv | 2025 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/40060499 |
Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering. | Padilla MS, Mrksich K, Wang Y, Haley RM, Li JJ, Han EL, El-Mayta R, Kim EH, Dias S, Gong N, Teerdhala SV, Han X, Chowdhary V, Xue L, Siddiqui Z, Yamagata HM, Kim D, Yoon IC, Wilson JM, Radhakrishnan R, Mitchell MJ | Nature communications | 39856035 | Nat Commun | 2025 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/39856035 |
Nanoparticles for nucleic acid delivery: Applications in cancer immunotherapy. | Mukalel AJ, Riley RS, Zhang R, Mitchell MJ | Cancer letters | 31100411 | Cancer Lett | 2019 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/31100411 |
A (Controlled) Spill of IL2 for Localized Treatment of Mesothelioma. | Palanki R, Swingle KL, Mitchell MJ | Clinical cancer research : an official journal of the American Association for Cancer Research | 36190329 | Clin Cancer Res | 2022 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/36190329 |
Testing the In Vitro and In Vivo Efficiency of mRNA-Lipid Nanoparticles Formulated by Microfluidic Mixing. | El-Mayta R, Padilla MS, Billingsley MM, Han X, Mitchell MJ | Journal of visualized experiments : JoVE | 36744791 | J Vis Exp | 2023 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/36744791 |
Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery. | Swingle KL, Billingsley MM, Bose SK, White B, Palanki R, Dave A, Patel SK, Gong N, Hamilton AG, Alameh MG, Weissman D, Peranteau WH, Mitchell MJ | Journal of controlled release : official journal of the Controlled Release Society | 34742747 | J Control Release | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34742747 |
Biomaterials for vaccine-based cancer immunotherapy. | Zhang R, Billingsley MM, Mitchell MJ | Journal of controlled release : official journal of the Controlled Release Society | 30312721 | J Control Release | 2018 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/30312721 |
Delivery technologies for cancer immunotherapy. | Riley RS, June CH, Langer R, Mitchell MJ | Nature reviews. Drug discovery | 30622344 | Nat Rev Drug Discov | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30622344 |
Delivery technologies for in utero gene therapy. | Palanki R, Peranteau WH, Mitchell MJ | Advanced drug delivery reviews | 33181188 | Adv Drug Deliv Rev | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33181188 |
Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction. | Huang M, Yang F, Zhang D, Lin M, Duan H, El-Mayta R, Zhang L, Qin L, Shewale SV, Pei L, Mitchell MJ, Rader DJ, Fan Y, Gong Y | Nature cardiovascular research | 35571674 | Nat Cardiovasc Res | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35571674 |
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA. | Zhang D, Atochina-Vasserman EN, Maurya DS, Huang N, Xiao Q, Ona N, Liu M, Shahnawaz H, Ni H, Kim K, Billingsley MM, Pochan DJ, Mitchell MJ, Weissman D, Percec V | Journal of the American Chemical Society | 34324336 | J Am Chem Soc | 2021 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/34324336 |
Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying length. | Mrksich K, Padilla MS, Joseph RA, Han EL, Kim D, Palanki R, Xu J, Mitchell MJ | Journal of biomedical materials research. Part A | 38487970 | J Biomed Mater Res A | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/38487970 |
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy. | Swingle KL, Safford HC, Geisler HC, Hamilton AG, Thatte AS, Billingsley MM, Joseph RA, Mrksich K, Padilla MS, Ghalsasi AA, Alameh MG, Weissman D, Mitchell MJ | Journal of the American Chemical Society | 36789893 | J Am Chem Soc | 2023 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/36789893 |
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines. | Han X, Alameh MG, Butowska K, Knox JJ, Lundgreen K, Ghattas M, Gong N, Xue L, Xu Y, Lavertu M, Bates P, Xu J, Nie G, Zhong Y, Weissman D, Mitchell MJ | Nature nanotechnology | 37365276 | Nat Nanotechnol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37365276 |
Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease. | Palanki R, Bose SK, Dave A, White BM, Berkowitz C, Luks V, Yaqoob F, Han E, Swingle KL, Menon P, Hodgson E, Biswas A, Billingsley MM, Li L, Yiping F, Carpenter M, Trokhan A, Yeo J, Johana N, Wan TY, Alameh MG, Bennett FC, Storm PB, Jain R, Chan J, Weissman D, Mitchell MJ, Peranteau WH | ACS nano | 37458484 | ACS Nano | 2023 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/37458484 |
Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery. | Gong N, Zhong W, Alameh MG, Han X, Xue L, El-Mayta R, Zhao G, Vaughan AE, Qin Z, Xu F, Hamilton AG, Kim D, Xu J, Kim J, Teng X, Li J, Liang XJ, Weissman D, Guo W, Mitchell MJ | Nature materials | 39223270 | Nat Mater | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39223270 |
EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta. | Geisler HC, Ghalsasi AA, Safford HC, Swingle KL, Thatte AS, Mukalel AJ, Gong N, Hamilton AG, Han EL, Nachod BE, Padilla MS, Mitchell MJ | Journal of controlled release : official journal of the Controlled Release Society | 38789090 | J Control Release | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38789090 |
Enhancing in situ cancer vaccines using delivery technologies. | Gong N, Alameh MG, El-Mayta R, Xue L, Weissman D, Mitchell MJ | Nature reviews. Drug discovery | 38951662 | Nat Rev Drug Discov | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38951662 |
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines. | Shepherd SJ, Han X, Mukalel AJ, El-Mayta R, Thatte AS, Wu J, Padilla MS, Alameh MG, Srikumar N, Lee D, Weissman D, Issadore D, Mitchell MJ | Proceedings of the National Academy of Sciences of the United States of America | 37556502 | Proc Natl Acad Sci U S A | 2023 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/37556502 |
Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering. | Hamilton AG, Swingle KL, Joseph RA, Mai D, Gong N, Billingsley MM, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ | Advanced healthcare materials | 37602495 | Adv Healthc Mater | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37602495 |
Predictive High-Throughput Platform for Dual Screening of mRNA Lipid Nanoparticle Blood-Brain Barrier Transfection and Crossing. | Han EL, Padilla MS, Palanki R, Kim D, Mrksich K, Li JJ, Tang S, Yoon IC, Mitchell MJ | Nano letters | 38259198 | Nano Lett | 2024 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/38259198 |
Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering. | Mukalel AJ, Hamilton AG, Billingsley MM, Li J, Thatte AS, Han X, Safford HC, Padilla MS, Papp T, Parhiz H, Weissman D, Mitchell MJ | Advanced functional materials | 39628840 | Adv Funct Mater | 2024 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/39628840 |
Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery. | Xue L, Zhao G, Gong N, Han X, Shepherd SJ, Xiong X, Xiao Z, Palanki R, Xu J, Swingle KL, Warzecha CC, El-Mayta R, Chowdhary V, Yoon IC, Xu J, Cui J, Shi Y, Alameh MG, Wang K, Wang L, Pochan DJ, Weissman D, Vaughan AE, Wilson JM, Mitchell MJ | Nature nanotechnology | 39354147 | Nat Nanotechnol | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39354147 |
Measuring Vascular Permeability In Vivo. | Meijer EF, Baish JW, Padera TP, Fukumura D | Methods in molecular biology (Clifton, N.J.) | 27581015 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27581015 |
Growth and Immune Evasion of Lymph Node Metastasis. | Jones D, Pereira ER, Padera TP | Frontiers in oncology | 29527513 | Front Oncol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29527513 |
Targeting CXCR4-dependent immunosuppressive Ly6C(low) monocytes improves antiangiogenic therapy in colorectal cancer. | Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D | Proceedings of the National Academy of Sciences of the United States of America | 28900008 | Proc Natl Acad Sci U S A | 2017 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/28900008 |
Simultaneous measurements of lymphatic vessel contraction, flow and valve dynamics in multiple lymphangions using optical coherence tomography. | Blatter C, Meijer EFJ, Padera TP, Vakoc BJ | Journal of biophotonics | 28700145 | J Biophotonics | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28700145 |
Lymphatic function measurements influenced by contrast agent volume and body position. | Bouta EM, Blatter C, Ruggieri TA, Meijer EF, Munn LL, Vakoc BJ, Padera TP | JCI insight | 29367467 | JCI Insight | 2018 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/29367467 |
Novel molecular pathways in Gorham disease: implications for treatment. | Hagendoorn J, Yock TI, Borel Rinkes IH, Padera TP, Ebb DH | Pediatric blood & cancer | 24214028 | Pediatr Blood Cancer | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24214028 |
Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment. | Kirkpatrick ND, Chung E, Cook DC, Han X, Gruionu G, Liao S, Munn LL, Padera TP, Fukumura D, Jain RK | Intravital | 24353926 | Intravital | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/24353926 |
Cardiac and inflammatory biomarkers do not correlate with volume of heart or lung receiving radiation. | Kuo AH, Ancukiewicz M, Kozak KR, Yock TI, Padera TP | Radiation oncology (London, England) | 25573181 | Radiat Oncol | 2015 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/25573181 |
Lymphatic vessels in health and disease. | Kesler CT, Liao S, Munn LL, Padera TP | Wiley interdisciplinary reviews. Systems biology and medicine | 23209022 | Wiley Interdiscip Rev Syst Biol Med | 2013 Jan-Feb | https://www.ncbi.nlm.nih.gov/pubmed/23209022 |
In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography. | Blatter C, Meijer EF, Nam AS, Jones D, Bouma BE, Padera TP, Vakoc BJ | Scientific reports | 27377852 | Sci Rep | 2016 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/27377852 |
Imaging the lymphatic system. | Munn LL, Padera TP | Microvascular research | 24956510 | Microvasc Res | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24956510 |
Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure. | Chauhan VP, Boucher Y, Ferrone CR, Roberge S, Martin JD, Stylianopoulos T, Bardeesy N, DePinho RA, Padera TP, Munn LL, Jain RK | Cancer cell | 25026209 | Cancer Cell | 2014 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/25026209 |
A retrospective analysis of commonly prescribed medications and the risk of developing breast cancer related lymphedema. | Meijer EF, Bouta EM, Mendonca C, Skolny MN, Salama LW, Taghian AG, Padera TP | Clinical research and trials | 32864167 | Clin Res Trials | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32864167 |
Synchronization and Random Triggering of Lymphatic Vessel Contractions. | Baish JW, Kunert C, Padera TP, Munn LL | PLoS computational biology | 27935958 | PLoS Comput Biol | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27935958 |
Murine chronic lymph node window for longitudinal intravital lymph node imaging. | Meijer EFJ, Jeong HS, Pereira ER, Ruggieri TA, Blatter C, Vakoc BJ, Padera TP | Nature protocols | 28683064 | Nat Protoc | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28683064 |
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. | Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D | The Journal of clinical investigation | 28691930 | J Clin Invest | 2017 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/28691930 |
Solid stress and elastic energy as measures of tumour mechanopathology. | Nia HT, Liu H, Seano G, Datta M, Jones D, Rahbari N, Incio J, Chauhan VP, Jung K, Martin JD, Askoxylakis V, Padera TP, Fukumura D, Boucher Y, Hornicek FJ, Grodzinsky AJ, Baish JW, Munn LL, Jain RK | Nature biomedical engineering | 28966873 | Nat Biomed Eng | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/28966873 |
Significance of lymph node metastasis in cancer dissemination of head and neck cancer. | Cho JK, Hyun SH, Choi N, Kim MJ, Padera TP, Choi JY, Jeong HS | Translational oncology | 25926078 | Transl Oncol | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25926078 |
Local failure in parameningeal rhabdomyosarcoma correlates with poor response to induction chemotherapy. | Ladra MM, Mandeville HC, Niemierko A, Padera TP, Friedmann AM, MacDonald SM, Ebb D, Chen YL, Tarbell NJ, Yock TI | International journal of radiation oncology, biology, physics | 25864172 | Int J Radiat Oncol Biol Phys | 2015 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/25864172 |
Reply to Davis: Nitric oxide regulates lymphatic contractions. | Kunert C, Baish JW, Liao S, Padera TP, Munn LL | Proceedings of the National Academy of Sciences of the United States of America | 26719425 | Proc Natl Acad Sci U S A | 2016 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/26719425 |
Inducible Nitric Oxide Synthase and CD11b(+)Gr1(+) Cells Impair Lymphatic Contraction of Tumor-Draining Lymphatic Vessels. | Liao S, Bouta EM, Morris LM, Jones D, Jain RK, Padera TP | Lymphatic research and biology | 30358484 | Lymphat Res Biol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30358484 |
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium. | Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, Wen PY, Lin NU, Grodzinsky AJ, Fukumura D, Huang P, Baish JW, Padera TP, Munn LL, Jain RK | Nature biomedical engineering | 30948807 | Nat Biomed Eng | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30948807 |
Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation. | Kesler CT, Pereira ER, Cui CH, Nelson GM, Masuck DJ, Baish JW, Padera TP | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 25977256 | FASEB J | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25977256 |
Method for the quantitative measurement of collecting lymphatic vessel contraction in mice. | Liao S, Jones D, Cheng G, Padera TP | Journal of biological methods | 25512945 | J Biol Methods | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25512945 |
Lymph node effective vascular permeability and chemotherapy uptake. | Meijer EFJ, Blatter C, Chen IX, Bouta E, Jones D, Pereira ER, Jung K, Vakoc BJ, Baish JW, Padera TP | Microcirculation (New York, N.Y. : 1994) | 28510992 | Microcirculation | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28510992 |
The Lymphatic System in Disease Processes and Cancer Progression. | Padera TP, Meijer EF, Munn LL | Annual review of biomedical engineering | 26863922 | Annu Rev Biomed Eng | 2016 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/26863922 |
Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression. | Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Kirkpatrick ND, Heishi T, Huang Y, Martin JD, Ager E, Samuel R, Wang S, Yazbek J, Vakoc BJ, Peterson RT, Padera TP, Duda DG, Fukumura D, Jain RK | Journal of the National Cancer Institute | 23899555 | J Natl Cancer Inst | 2013 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/23899555 |
Lymphatic function and immune regulation in health and disease. | Liao S, Padera TP | Lymphatic research and biology | 24024577 | Lymphat Res Biol | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/24024577 |
Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells. | Kesler CT, Kuo AH, Wong HK, Masuck DJ, Shah JL, Kozak KR, Held KD, Padera TP | Angiogenesis | 24201897 | Angiogenesis | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24201897 |
Editorial: rapid growth in the field of lymphatic biology. | Padera TP | Seminars in cell & developmental biology | 25868083 | Semin Cell Dev Biol | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25868083 |
Fate Mapping of Cancer Cells in Metastatic Lymph Nodes Using Photoconvertible Proteins. | Pereira ER, Kedrin D, Padera TP | Methods in molecular biology (Clifton, N.J.) | 33704727 | Methods Mol Biol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33704727 |
Solid stress impairs lymphocyte infiltration into lymph-node metastases. | Jones D, Wang Z, Chen IX, Zhang S, Banerji R, Lei PJ, Zhou H, Xiao V, Kwong C, van Wijnbergen JWM, Pereira ER, Vakoc BJ, Huang P, Nia HT, Padera TP | Nature biomedical engineering | 34282290 | Nat Biomed Eng | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34282290 |
Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction. | Jones D, Meijer EFJ, Blatter C, Liao S, Pereira ER, Bouta EM, Jung K, Chin SM, Huang P, Munn LL, Vakoc BJ, Otto M, Padera TP | Science translational medicine | 29343625 | Sci Transl Med | 2018 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/29343625 |
Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice. | Pereira ER, Kedrin D, Seano G, Gautier O, Meijer EFJ, Jones D, Chin SM, Kitahara S, Bouta EM, Chang J, Beech E, Jeong HS, Carroll MC, Taghian AG, Padera TP | Science (New York, N.Y.) | 29567713 | Science | 2018 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/29567713 |
The lymph node microenvironment and its role in the progression of metastatic cancer. | Pereira ER, Jones D, Jung K, Padera TP | Seminars in cell & developmental biology | 25620792 | Semin Cell Dev Biol | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25620792 |
Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases. | Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP | Journal of the National Cancer Institute | 26063793 | J Natl Cancer Inst | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26063793 |
Mechanobiological oscillators control lymph flow. | Kunert C, Baish JW, Liao S, Padera TP, Munn LL | Proceedings of the National Academy of Sciences of the United States of America | 26283382 | Proc Natl Acad Sci U S A | 2015 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/26283382 |
Kinetochore components are required for central spindle assembly. | Maton G, Edwards F, Lacroix B, Stefanutti M, Laband K, Lieury T, Kim T, Espeut J, Canman JC, Dumont J | Nature cell biology | 25866924 | Nat Cell Biol | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25866924 |
Kinetochore components are required for central spindle assembly. | Maton G, Edwards F, Lacroix B, Stefanutti M, Laband K, Lieury T, Kim T, Espeut J, Canman JC, Dumont J | Nature cell biology | 26123112 | Nat Cell Biol | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26123112 |
Using fast-acting temperature-sensitive mutants to study cell division in Caenorhabditis elegans. | Davies T, Sundaramoorthy S, Jordan SN, Shirasu-Hiza M, Dumont J, Canman JC | Methods in cell biology | 28065312 | Methods Cell Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28065312 |
CYK-4 regulates Rac, but not Rho, during cytokinesis. | Zhuravlev Y, Hirsch SM, Jordan SN, Dumont J, Shirasu-Hiza M, Canman JC | Molecular biology of the cell | 28298491 | Mol Biol Cell | 2017 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/28298491 |
High-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis. | Davies T, Jordan SN, Chand V, Sees JA, Laband K, Carvalho AX, Shirasu-Hiza M, Kovar DR, Dumont J, Canman JC | Developmental cell | 25073157 | Dev Cell | 2014 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/25073157 |
Cell-intrinsic and -extrinsic mechanisms promote cell-type-specific cytokinetic diversity. | Davies T, Kim HX, Romano Spica N, Lesea-Pringle BJ, Dumont J, Shirasu-Hiza M, Canman JC | eLife | 30028292 | Elife | 2018 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/30028292 |
Rho GTPases in animal cell cytokinesis: an occupation by the one percent. | Jordan SN, Canman JC | Cytoskeleton (Hoboken, N.J.) | 23047851 | Cytoskeleton (Hoboken) | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23047851 |
Dietary Restriction Extends the Lifespan of Circadian Mutants tim and per. | Ulgherait M, Chen A, Oliva MK, Kim HX, Canman JC, Ja WW, Shirasu-Hiza M | Cell metabolism | 27916531 | Cell Metab | 2016 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/27916531 |
A Drosophila model of Fragile X syndrome exhibits defects in phagocytosis by innate immune cells. | O'Connor RM, Stone EF, Wayne CR, Marcinkevicius EV, Ulgherait M, Delventhal R, Pantalia MM, Hill VM, Zhou CG, McAllister S, Chen A, Ziegenfuss JS, Grueber WB, Canman JC, Shirasu-Hiza MM | The Journal of cell biology | 28223318 | J Cell Biol | 2017 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/28223318 |
Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes. | Gigant E, Stefanutti M, Laband K, Gluszek-Kustusz A, Edwards F, Lacroix B, Maton G, Canman JC, Welburn JPI, Dumont J | Development (Cambridge, England) | 28289130 | Development | 2017 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/28289130 |
Stuck in the middle: Rac, adhesion, and cytokinesis. | Davies T, Canman JC | The Journal of cell biology | 22945931 | J Cell Biol | 2012 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/22945931 |
period-Regulated Feeding Behavior and TOR Signaling Modulate Survival of Infection. | Allen VW, O'Connor RM, Ulgherait M, Zhou CG, Stone EF, Hill VM, Murphy KR, Canman JC, Ja WW, Shirasu-Hiza MM | Current biology : CB | 26748856 | Curr Biol | 2016 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/26748856 |
period-Regulated Feeding Behavior and TOR Signaling Modulate Survival of Infection. | Allen VW, O'Connor RM, Ulgherait M, Zhou CG, Stone EF, Hill VM, Murphy KR, Canman JC, Ja WW, Shirasu-Hiza MM | Current biology : CB | 27218838 | Curr Biol | 2016 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/27218838 |
FLIRT: fast local infrared thermogenetics for subcellular control of protein function. | Hirsch SM, Sundaramoorthy S, Davies T, Zhuravlev Y, Waters JC, Shirasu-Hiza M, Dumont J, Canman JC | Nature methods | 30377360 | Nat Methods | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30377360 |
Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing. | Lacroix B, Letort G, Pitayu L, Sallé J, Stefanutti M, Maton G, Ladouceur AM, Canman JC, Maddox PS, Maddox AS, Minc N, Nédélec F, Dumont J | Developmental cell | 29787710 | Dev Cell | 2018 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/29787710 |
Cortical PAR polarity proteins promote robust cytokinesis during asymmetric cell division. | Jordan SN, Davies T, Zhuravlev Y, Dumont J, Shirasu-Hiza M, Canman JC | The Journal of cell biology | 26728855 | J Cell Biol | 2016 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/26728855 |
Low Efficiency Upconversion Nanoparticles for High-Resolution Coalignment of Near-Infrared and Visible Light Paths on a Light Microscope. | Sundaramoorthy S, Garcia Badaracco A, Hirsch SM, Park JH, Davies T, Dumont J, Shirasu-Hiza M, Kummel AC, Canman JC | ACS applied materials & interfaces | 28221018 | ACS Appl Mater Interfaces | 2017 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/28221018 |
Effect of Competitive Surface Functionalization on Dual-Modality Fluorescence and Magnetic Resonance Imaging of Single-Walled Carbon Nanotubes. | Hong T, Lazarenko RM, Colvin DC, Flores RL, Zhang Q, Xu YQ | The journal of physical chemistry. C, Nanomaterials and interfaces | 26644813 | J Phys Chem C Nanomater Interfaces | 2012 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/26644813 |
Ammonium chloride alters neuronal excitability and synaptic vesicle release. | Lazarenko RM, DelBove CE, Strothman CE, Zhang Q | Scientific reports | 28698583 | Sci Rep | 2017 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/28698583 |
A Stem Cell-Derived Platform for Studying Single Synaptic Vesicles in Dopaminergic Synapses. | Gu H, Lazarenko RM, Koktysh D, Iacovitti L, Zhang Q | Stem cells translational medicine | 26025981 | Stem Cells Transl Med | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26025981 |
Fluorescent Measurement of Synaptic Activity Using FM Dyes in Dissociated Hippocampal Cultured Neurons. | Lazarenko RM, DelBove CE, Zhang Q | Bio-protocol | 29552593 | Bio Protoc | 2018 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/29552593 |
Reciprocal modulation between amyloid precursor protein and synaptic membrane cholesterol revealed by live cell imaging. | DelBove CE, Strothman CE, Lazarenko RM, Huang H, Sanders CR, Zhang Q | Neurobiology of disease | 30885793 | Neurobiol Dis | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30885793 |
Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis: Implications for Scleroderma. | Mitra A, Luna JI, Marusina AI, Merleev A, Kundu-Raychaudhuri S, Fiorentino D, Raychaudhuri SP, Maverakis E | The Journal of investigative dermatology | 26134944 | J Invest Dermatol | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26134944 |
Serum levels of innate immunity cytokines are elevated in dogs with metaphyseal osteopathy (hypertrophic osteodytrophy) during active disease and remission. | Safra N, Hitchens PL, Maverakis E, Mitra A, Korff C, Johnson E, Kol A, Bannasch MJ, Pedersen NC, Bannasch DL | Veterinary immunology and immunopathology | 27590423 | Vet Immunol Immunopathol | 2016 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/27590423 |
Salmonella Typhimurium Enzymatically Landscapes the Host Intestinal Epithelial Cell (IEC) Surface Glycome to Increase Invasion. | Park D, Arabyan N, Williams CC, Song T, Mitra A, Weimer BC, Maverakis E, Lebrilla CB | Molecular & cellular proteomics : MCP | 27754876 | Mol Cell Proteomics | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27754876 |
Meta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A. | Merleev AA, Marusina AI, Ma C, Elder JT, Tsoi LC, Raychaudhuri SP, Weidinger S, Wang EA, Adamopoulos IE, Luxardi G, Gudjonsson JE, Shimoda M, Maverakis E | JCI insight | 29997305 | JCI Insight | 2018 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/29997305 |
Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. | Sun Y, Reid B, Ferreira F, Luxardi G, Ma L, Lokken KL, Zhu K, Xu G, Sun Y, Ryzhuk V, Guo BP, Lebrilla CB, Maverakis E, Mogilner A, Zhao M | PLoS biology | 30964858 | PLoS Biol | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30964858 |
NKG2C, HLA-E and their association with psoriasis. | Patel F, Marusina AI, Duong C, Adamopoulos IE, Maverakis E | Experimental dermatology | 24279916 | Exp Dermatol | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24279916 |
Characteristic Changes in Cell Surface Glycosylation Accompany Intestinal Epithelial Cell (IEC) Differentiation: High Mannose Structures Dominate the Cell Surface Glycome of Undifferentiated Enterocytes. | Park D, Brune KA, Mitra A, Marusina AI, Maverakis E, Lebrilla CB | Molecular & cellular proteomics : MCP | 26355101 | Mol Cell Proteomics | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26355101 |
Classic Ulcerative Pyoderma Gangrenosum Is a T Cell-Mediated Disease Targeting Follicular Adnexal Structures: A Hypothesis Based on Molecular and Clinicopathologic Studies. | Wang EA, Steel A, Luxardi G, Mitra A, Patel F, Cheng MY, Wilken R, Kao J, de Ga K, Sultani H, Merleev AA, Marusina AI, Brassard A, Fung MA, Konia T, Shimoda M, Maverakis E | Frontiers in immunology | 29379508 | Front Immunol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29379508 |
Trends in National Institutes of Health Funding of Principal Investigators in Dermatology Research by Academic Degree and Sex. | Cheng MY, Sukhov A, Sultani H, Kim K, Maverakis E | JAMA dermatology | 27191545 | JAMA Dermatol | 2016 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/27191545 |
Surface Glycans Regulate Salmonella Infection-Dependent Directional Switch in Macrophage Galvanotaxis Independent of NanH. | Sun YH, Luxardi G, Xu G, Zhu K, Reid B, Guo BP, Lebrilla CB, Maverakis E, Zhao M | Infection and immunity | 34662214 | Infect Immun | 2022 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/34662214 |
Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review. | Maverakis E, Kim K, Shimoda M, Gershwin ME, Patel F, Wilken R, Raychaudhuri S, Ruhaak LR, Lebrilla CB | Journal of autoimmunity | 25578468 | J Autoimmun | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25578468 |
Clonal Vγ6(+)Vδ4(+) T cells promote IL-17-mediated immunity against Staphylococcus aureus skin infection. | Marchitto MC, Dillen CA, Liu H, Miller RJ, Archer NK, Ortines RV, Alphonse MP, Marusina AI, Merleev AA, Wang Y, Pinsker BL, Byrd AS, Brown ID, Ravipati A, Zhang E, Cai SS, Limjunyawong N, Dong X, Yeaman MR, Simon SI, Shen W, Durum SK, O'Brien RL, Maverakis E, Miller LS | Proceedings of the National Academy of Sciences of the United States of America | 31088972 | Proc Natl Acad Sci U S A | 2019 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/31088972 |
Peristomal pyoderma gangrenosum: An exceedingly rare and overdiagnosed entity? | Le ST, Wang JZ, Alexanian C, Ellis S, Martinez-Alvarado YC, Johng S, Sood A, Maverakis E | Journal of the American Academy of Dermatology | 30772334 | J Am Acad Dermatol | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30772334 |
Glycan biomarkers of autoimmunity and bile acid-associated alterations of the human glycome: Primary biliary cirrhosis and primary sclerosing cholangitis-specific glycans. | Maverakis E, Merleev AA, Park D, Kailemia MJ, Xu G, Ruhaak LR, Kim K, Hong Q, Li Q, Leung P, Liakos W, Wan YY, Bowlus CL, Marusina AI, Lal NN, Xie Y, Luxardi G, Lebrilla CB | Clinical immunology (Orlando, Fla.) | 34403816 | Clin Immunol | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34403816 |
Interactions of the Immune System with Skin and Bone Tissue in Psoriatic Arthritis: A Comprehensive Review. | Sukhov A, Adamopoulos IE, Maverakis E | Clinical reviews in allergy & immunology | 26780035 | Clin Rev Allergy Immunol | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26780035 |
Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes. | Merleev AA, Le ST, Alexanian C, Toussi A, Xie Y, Marusina AI, Watkins SM, Patel F, Billi AC, Wiedemann J, Izumiya Y, Kumar A, Uppala R, Kahlenberg JM, Liu FT, Adamopoulos IE, Wang EA, Ma C, Cheng MY, Xiong H, Kirane A, Luxardi G, Andersen B, Tsoi LC, Lebrilla CB, Gudjonsson JE, Maverakis E | JCI insight | 35900871 | JCI Insight | 2022 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/35900871 |
Controlling the Release of Small, Bioactive Proteins via Dual Mechanisms with Therapeutic Potential. | Kharkar PM, Scott RA, Olney LP, LeValley PJ, Maverakis E, Kiick KL, Kloxin AM | Advanced healthcare materials | 29024487 | Adv Healthc Mater | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29024487 |
Oncolytic Reactivation of KSHV as a Therapeutic Approach for Primary Effusion Lymphoma. | Zhou F, Shimoda M, Olney L, Lyu Y, Tran K, Jiang G, Nakano K, Davis RR, Tepper CG, Maverakis E, Campbell M, Li Y, Dandekar S, Izumiya Y | Molecular cancer therapeutics | 28847988 | Mol Cancer Ther | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28847988 |
Membrane glycomics reveal heterogeneity and quantitative distribution of cell surface sialylation. | Park DD, Xu G, Wong M, Phoomak C, Liu M, Haigh NE, Wongkham S, Yang P, Maverakis E, Lebrilla CB | Chemical science | 30123482 | Chem Sci | 2018 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/30123482 |
A Method for Comprehensive Glycosite-Mapping and Direct Quantitation of Serum Glycoproteins. | Hong Q, Ruhaak LR, Stroble C, Parker E, Huang J, Maverakis E, Lebrilla CB | Journal of proteome research | 26510530 | J Proteome Res | 2015 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/26510530 |
Metastasis of cholangiocarcinoma is promoted by extended high-mannose glycans. | Park DD, Phoomak C, Xu G, Olney LP, Tran KA, Park SS, Haigh NE, Luxardi G, Lert-Itthiporn W, Shimoda M, Li Q, Matoba N, Fierro F, Wongkham S, Maverakis E, Lebrilla CB | Proceedings of the National Academy of Sciences of the United States of America | 32213588 | Proc Natl Acad Sci U S A | 2020 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/32213588 |
Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection. | Dillen CA, Pinsker BL, Marusina AI, Merleev AA, Farber ON, Liu H, Archer NK, Lee DB, Wang Y, Ortines RV, Lee SK, Marchitto MC, Cai SS, Ashbaugh AG, May LS, Holland SM, Freeman AF, Miller LG, Yeaman MR, Simon SI, Milner JD, Maverakis E, Miller LS | The Journal of clinical investigation | 29400698 | J Clin Invest | 2018 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/29400698 |
A Phase I Study of the Combination of Rituximab and Ipilimumab in Patients with Relapsed/Refractory B-Cell Lymphoma. | Tuscano JM, Maverakis E, Groshen S, Tsao-Wei D, Luxardi G, Merleev AA, Beaven A, DiPersio JF, Popplewell L, Chen R, Kirschbaum M, Schroeder MA, Newman EM | Clinical cancer research : an official journal of the American Association for Cancer Research | 31481504 | Clin Cancer Res | 2019 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/31481504 |
International consensus criteria for the diagnosis of Raynaud's phenomenon. | Maverakis E, Patel F, Kronenberg DG, Chung L, Fiorentino D, Allanore Y, Guiducci S, Hesselstrand R, Hummers LK, Duong C, Kahaleh B, Macgregor A, Matucci-Cerinic M, Wollheim FA, Mayes MD, Gershwin ME | Journal of autoimmunity | 24491823 | J Autoimmun | 2014 Feb-Mar | https://www.ncbi.nlm.nih.gov/pubmed/24491823 |
T cell clonal expansions detected in patients with primary biliary cirrhosis express CX3CR1. | Zhang W, Ono Y, Miyamura Y, Bowlus CL, Gershwin ME, Maverakis E | Journal of autoimmunity | 21636249 | J Autoimmun | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21636249 |
ITK inhibition for the targeted treatment of CTCL. | Bustos-Villalobos I, Bergstrom JW, Haigh NE, Luna JI, Mitra A, Marusina AI, Merleev AA, Wang EA, Sukhov A, Sultani H, Liu R, Bhardwaj G, Guo W, Kung HJ, Lam KS, Maverakis E | Journal of dermatological science | 28434812 | J Dermatol Sci | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28434812 |
Persistence of Autoreactive IgA-Secreting B Cells Despite Multiple Immunosuppressive Medications Including Rituximab. | He Y, Shimoda M, Ono Y, Villalobos IB, Mitra A, Konia T, Grando SA, Zone JJ, Maverakis E | JAMA dermatology | 25901938 | JAMA Dermatol | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25901938 |
CD4(+) virtual memory: Antigen-inexperienced T cells reside in the naïve, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity. | Marusina AI, Ono Y, Merleev AA, Shimoda M, Ogawa H, Wang EA, Kondo K, Olney L, Luxardi G, Miyamura Y, Yilma TD, Villalobos IB, Bergstrom JW, Kronenberg DG, Soulika AM, Adamopoulos IE, Maverakis E | Journal of autoimmunity | 27894837 | J Autoimmun | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/27894837 |
γδ T cells in rheumatic diseases: from fundamental mechanisms to autoimmunity. | Nguyen CT, Maverakis E, Eberl M, Adamopoulos IE | Seminars in immunopathology | 31506867 | Semin Immunopathol | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31506867 |
A site-specific map of the human plasma glycome and its age and gender-associated alterations. | Merleev AA, Park D, Xie Y, Kailemia MJ, Xu G, Ruhaak LR, Kim K, Hong Q, Li Q, Patel F, Wan YY, Marusina AI, Adamopoulos IE, Lal NN, Mitra A, Le ST, Shimoda M, Luxardi G, Lebrilla CB, Maverakis E | Scientific reports | 33060657 | Sci Rep | 2020 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/33060657 |
HDL Glycoprotein Composition and Site-Specific Glycosylation Differentiates Between Clinical Groups and Affects IL-6 Secretion in Lipopolysaccharide-Stimulated Monocytes. | Krishnan S, Shimoda M, Sacchi R, Kailemia MJ, Luxardi G, Kaysen GA, Parikh AN, Ngassam VN, Johansen K, Chertow GM, Grimes B, Smilowitz JT, Maverakis E, Lebrilla CB, Zivkovic AM | Scientific reports | 28287093 | Sci Rep | 2017 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/28287093 |
Regeneration and experimental orthotopic transplantation of a bioengineered kidney. | Song JJ, Guyette JP, Gilpin SE, Gonzalez G, Vacanti JP, Ott HC | Nature medicine | 23584091 | Nat Med | 2013 May | https://www.ncbi.nlm.nih.gov/pubmed/23584091 |
Perfusion Decellularization of Discarded Human Kidneys: A Valuable Platform for Organ Regeneration. | Ott HC | Transplantation | 26203856 | Transplantation | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26203856 |
Engineering pulmonary vasculature in decellularized rat and human lungs. | Ren X, Moser PT, Gilpin SE, Okamoto T, Wu T, Tapias LF, Mercier FE, Xiong L, Ghawi R, Scadden DT, Mathisen DJ, Ott HC | Nature biotechnology | 26368048 | Nat Biotechnol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26368048 |
Design and validation of a clinical-scale bioreactor for long-term isolated lung culture. | Charest JM, Okamoto T, Kitano K, Yasuda A, Gilpin SE, Mathisen DJ, Ott HC | Biomaterials | 25818415 | Biomaterials | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25818415 |
Ex vivo non-invasive assessment of cell viability and proliferation in bio-engineered whole organ constructs. | Ren X, Tapias LF, Jank BJ, Mathisen DJ, Lanuti M, Ott HC | Biomaterials | 25818417 | Biomaterials | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25818417 |
Creation of a Bioengineered Skin Flap Scaffold with a Perfusable Vascular Pedicle. | Jank BJ, Goverman J, Guyette JP, Charest JM, Randolph M, Gaudette GR, Gershlak JR, Purschke M, Javorsky E, Nazarian RM, Leonard DA, Cetrulo CL, Austen WG, Ott HC | Tissue engineering. Part A | 28323545 | Tissue Eng Part A | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28323545 |
Decellularized scaffolds as a platform for bioengineered organs. | Tapias LF, Ott HC | Current opinion in organ transplantation | 24480969 | Curr Opin Organ Transplant | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24480969 |
Enhanced lung epithelial specification of human induced pluripotent stem cells on decellularized lung matrix. | Gilpin SE, Ren X, Okamoto T, Guyette JP, Mou H, Rajagopal J, Mathisen DJ, Vacanti JP, Ott HC | The Annals of thoracic surgery | 25149047 | Ann Thorac Surg | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25149047 |
Perfusion decellularization of human and porcine lungs: bringing the matrix to clinical scale. | Gilpin SE, Guyette JP, Gonzalez G, Ren X, Asara JM, Mathisen DJ, Vacanti JP, Ott HC | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | 24365767 | J Heart Lung Transplant | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24365767 |
Bioengineering of functional human induced pluripotent stem cell-derived intestinal grafts. | Kitano K, Schwartz DM, Zhou H, Gilpin SE, Wojtkiewicz GR, Ren X, Sommer CA, Capilla AV, Mathisen DJ, Goldstein AM, Mostoslavsky G, Ott HC | Nature communications | 29018244 | Nat Commun | 2017 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/29018244 |
Bioengineering kidneys for transplantation. | Madariaga ML, Ott HC | Seminars in nephrology | 25217267 | Semin Nephrol | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25217267 |
Engineered composite tissue as a bioartificial limb graft. | Jank BJ, Xiong L, Moser PT, Guyette JP, Ren X, Cetrulo CL, Leonard DA, Fernandez L, Fagan SP, Ott HC | Biomaterials | 26004237 | Biomaterials | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26004237 |
Regenerative potential of human airway stem cells in lung epithelial engineering. | Gilpin SE, Charest JM, Ren X, Tapias LF, Wu T, Evangelista-Leite D, Mathisen DJ, Ott HC | Biomaterials | 27622532 | Biomaterials | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27622532 |
Metabolic glycan labeling and chemoselective functionalization of native biomaterials. | Ren X, Evangelista-Leite D, Wu T, Rajab TK, Moser PT, Kitano K, Economopoulos KP, Gorman DE, Bloom JP, Tan JJ, Gilpin SE, Zhou H, Mathisen DJ, Ott HC | Biomaterials | 30118980 | Biomaterials | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30118980 |
Bioengineering Human Myocardium on Native Extracellular Matrix. | Guyette JP, Charest JM, Mills RW, Jank BJ, Moser PT, Gilpin SE, Gershlak JR, Okamoto T, Gonzalez G, Milan DJ, Gaudette GR, Ott HC | Circulation research | 26503464 | Circ Res | 2016 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/26503464 |
Membrane-Targeting DCAP Analogues with Broad-Spectrum Antibiotic Activity against Pathogenic Bacteria. | Hurley KA, Heinrich VA, Hershfield JR, Demons ST, Weibel DB | ACS medicinal chemistry letters | 25941556 | ACS Med Chem Lett | 2015 Apr 9 | https://www.ncbi.nlm.nih.gov/pubmed/25941556 |
Bacterial growth and adaptation in microdroplet chemostats. | Jakiela S, Kaminski TS, Cybulski O, Weibel DB, Garstecki P | Angewandte Chemie (International ed. in English) | 23832572 | Angew Chem Int Ed Engl | 2013 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/23832572 |
Small Molecule Chelators Reveal That Iron Starvation Inhibits Late Stages of Bacterial Cytokinesis. | Santos TMA, Lammers MG, Zhou M, Sparks IL, Rajendran M, Fang D, De Jesus CLY, Carneiro GFR, Cui Q, Weibel DB | ACS chemical biology | 29227619 | ACS Chem Biol | 2018 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/29227619 |
Localization of anionic phospholipids in Escherichia coli cells. | Oliver PM, Crooks JA, Leidl M, Yoon EJ, Saghatelian A, Weibel DB | Journal of bacteriology | 25002539 | J Bacteriol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25002539 |
Structure-activity studies of divin: an inhibitor of bacterial cell division. | Zhou M, Eun YJ, Guzei IA, Weibel DB | ACS medicinal chemistry letters | 24044050 | ACS Med Chem Lett | 2013 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/24044050 |
Physicochemical regulation of biofilm formation. | Renner LD, Weibel DB | MRS bulletin | 22125358 | MRS Bull | 2011 May | https://www.ncbi.nlm.nih.gov/pubmed/22125358 |
Polar localization of Escherichia coli chemoreceptors requires an intact Tol-Pal complex. | Santos TM, Lin TY, Rajendran M, Anderson SM, Weibel DB | Molecular microbiology | 24720726 | Mol Microbiol | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24720726 |
Gyramides prevent bacterial growth by inhibiting DNA gyrase and altering chromosome topology. | Rajendram M, Hurley KA, Foss MH, Thornton KM, Moore JT, Shaw JT, Weibel DB | ACS chemical biology | 24712739 | ACS Chem Biol | 2014 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/24712739 |
Bacterial Cell Mechanics. | Auer GK, Weibel DB | Biochemistry | 28666084 | Biochemistry | 2017 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/28666084 |
Measuring the stiffness of bacterial cells from growth rates in hydrogels of tunable elasticity. | Tuson HH, Auer GK, Renner LD, Hasebe M, Tropini C, Salick M, Crone WC, Gopinathan A, Huang KC, Weibel DB | Molecular microbiology | 22548341 | Mol Microbiol | 2012 Jun | https://www.ncbi.nlm.nih.gov/pubmed/22548341 |
Using liquid crystals to reveal how mechanical anisotropy changes interfacial behaviors of motile bacteria. | Mushenheim PC, Trivedi RR, Weibel DB, Abbott NL | Biophysical journal | 24988359 | Biophys J | 2014 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/24988359 |
Microfluidics for High School Chemistry Students. | Hemling M, Crooks JA, Oliver PM, Brenner K, Gilbertson J, Lisensky GC, Weibel DB | Journal of chemical education | 25584013 | J Chem Educ | 2014 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/25584013 |
A chemist building paths to cell biology. | Weibel DB | Molecular biology of the cell | 24174456 | Mol Biol Cell | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24174456 |
Divin: a small molecule inhibitor of bacterial divisome assembly. | Eun YJ, Zhou M, Kiekebusch D, Schlimpert S, Trivedi RR, Bakshi S, Zhong Z, Wahlig TA, Thanbichler M, Weibel DB | Journal of the American Chemical Society | 23738839 | J Am Chem Soc | 2013 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/23738839 |
Anionic Phospholipids Stabilize RecA Filament Bundles in Escherichia coli. | Rajendram M, Zhang L, Reynolds BJ, Auer GK, Tuson HH, Ngo KV, Cox MM, Yethiraj A, Cui Q, Weibel DB | Molecular cell | 26481664 | Mol Cell | 2015 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/26481664 |
A Cardiolipin-Deficient Mutant of Rhodobacter sphaeroides Has an Altered Cell Shape and Is Impaired in Biofilm Formation. | Lin TY, Santos TM, Kontur WS, Donohue TJ, Weibel DB | Journal of bacteriology | 26283770 | J Bacteriol | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26283770 |
Decoding the Chemical Language of Motile Bacteria by Using High-Throughput Microfluidic Assays. | Crooks JA, Stilwell MD, Oliver PM, Zhong Z, Weibel DB | Chembiochem : a European journal of chemical biology | 26285783 | Chembiochem | 2015 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/26285783 |
5-Alkyloxytryptamines are membrane-targeting, broad-spectrum antibiotics. | Faulkner KC, Hurley KA, Weibel DB | Bioorganic & medicinal chemistry letters | 27765507 | Bioorg Med Chem Lett | 2016 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/27765507 |
Inhibitors of bacterial tubulin target bacterial membranes in vivo. | Foss MH, Eun YJ, Grove CI, Pauw DA, Sorto NA, Rensvold JW, Pagliarini DJ, Shaw JT, Weibel DB | MedChemComm | 23539337 | Medchemcomm | 2013 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/23539337 |
Bacteria-surface interactions. | Tuson HH, Weibel DB | Soft matter | 23930134 | Soft Matter | 2013 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/23930134 |
DCAP: a broad-spectrum antibiotic that targets the cytoplasmic membrane of bacteria. | Eun YJ, Foss MH, Kiekebusch D, Pauw DA, Westler WM, Thanbichler M, Weibel DB | Journal of the American Chemical Society | 22741745 | J Am Chem Soc | 2012 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/22741745 |
Bacterial Swarming Reduces Proteus mirabilis and Vibrio parahaemolyticus Cell Stiffness and Increases β-Lactam Susceptibility. | Auer GK, Oliver PM, Rajendram M, Lin TY, Yao Q, Jensen GJ, Weibel DB | mBio | 31594808 | mBio | 2019 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/31594808 |
Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness. | Trivedi RR, Crooks JA, Auer GK, Pendry J, Foik IP, Siryaporn A, Abbott NL, Gitai Z, Weibel DB | mBio | 30206169 | mBio | 2018 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/30206169 |
Draft Genome Sequences of Two Pairs of Human Intestinal Bifidobacterium longum subsp. longum Strains, 44B and 1-6B and 35B and 2-2B, Consecutively Isolated from Two Children after a 5-Year Time Period. | Shkoporov AN, Efimov BA, Khokhlova EV, Chaplin AV, Kafarskaya LI, Durkin AS, McCorrison J, Torralba M, Gillis M, Sutton G, Weibel DB, Nelson KE, Smeianov VV | Genome announcements | 23682142 | Genome Announc | 2013 May 16 | https://www.ncbi.nlm.nih.gov/pubmed/23682142 |
Flagellum density regulates Proteus mirabilis swarmer cell motility in viscous environments. | Tuson HH, Copeland MF, Carey S, Sacotte R, Weibel DB | Journal of bacteriology | 23144253 | J Bacteriol | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23144253 |
Dynamic self-assembly of motile bacteria in liquid crystals. | Mushenheim PC, Trivedi RR, Tuson HH, Weibel DB, Abbott NL | Soft matter | 24652584 | Soft Matter | 2014 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/24652584 |
Bacterial cellulose as a substrate for microbial cell culture. | Yin N, Santos TM, Auer GK, Crooks JA, Oliver PM, Weibel DB | Applied and environmental microbiology | 24441155 | Appl Environ Microbiol | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24441155 |
Studying biomolecule localization by engineering bacterial cell wall curvature. | Renner LD, Eswaramoorthy P, Ramamurthi KS, Weibel DB | PloS one | 24391905 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24391905 |
Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase. | Hurley KA, Santos TMA, Fensterwald MR, Rajendran M, Moore JT, Balmond EI, Blahnik BJ, Faulkner KC, Foss MH, Heinrich VA, Lammers MG, Moore LC, Reynolds GD, Shearn-Nance GP, Stearns BA, Yao ZW, Shaw JT, Weibel DB | MedChemComm | 30034678 | Medchemcomm | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/30034678 |
The outer membrane is an essential load-bearing element in Gram-negative bacteria. | Rojas ER, Billings G, Odermatt PD, Auer GK, Zhu L, Miguel A, Chang F, Weibel DB, Theriot JA, Huang KC | Nature | 30022160 | Nature | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30022160 |
Mechanical Genomics Identifies Diverse Modulators of Bacterial Cell Stiffness. | Auer GK, Lee TK, Rajendram M, Cesar S, Miguel A, Huang KC, Weibel DB | Cell systems | 27321372 | Cell Syst | 2016 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/27321372 |
Maspin binds to cardiolipin in mitochondria and triggers apoptosis. | Mahajan N, Hoover B, Rajendram M, Shi HY, Kawasaki K, Weibel DB, Zhang M | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 30786218 | FASEB J | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30786218 |
From swimming to swarming: Escherichia coli cell motility in two-dimensions. | Swiecicki JM, Sliusarenko O, Weibel DB | Integrative biology : quantitative biosciences from nano to macro | 24145500 | Integr Biol (Camb) | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24145500 |
Fluorogenic Enzyme-Responsive Micellar Nanoparticles. | Chien MP, Thompson MP, Lin EC, Gianneschi NC | Chemical science | 23585924 | Chem Sci | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23585924 |
Polymeric Gd-DOTA amphiphiles form spherical and fibril-shaped nanoparticle MRI contrast agents. | Randolph LM, LeGuyader CLM, Hahn ME, Andolina CM, Patterson JP, Mattrey RF, Millstone JE, Botta M, Scadeng M, Gianneschi NC | Chemical science | 30155069 | Chem Sci | 2016 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/30155069 |
Intracellular mRNA regulation with self-assembled locked nucleic acid polymer nanoparticles. | Rush AM, Nelles DA, Blum AP, Barnhill SA, Tatro ET, Yeo GW, Gianneschi NC | Journal of the American Chemical Society | 24827740 | J Am Chem Soc | 2014 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/24827740 |
Polycatechol Nanoparticle MRI Contrast Agents. | Li Y, Huang Y, Wang Z, Carniato F, Xie Y, Patterson JP, Thompson MP, Andolina CM, Ditri TB, Millstone JE, Figueroa JS, Rinehart JD, Scadeng M, Botta M, Gianneschi NC | Small (Weinheim an der Bergstrasse, Germany) | 26681255 | Small | 2016 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/26681255 |
Polymerization of a peptide-based enzyme substrate. | Hahn ME, Randolph LM, Adamiak L, Thompson MP, Gianneschi NC | Chemical communications (Cambridge, England) | 23450132 | Chem Commun (Camb) | 2013 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/23450132 |
Blending block copolymer micelles in solution; Obstacles of blending. | Wright DB, Patterson JP, Gianneschi NC, Chassenieux C, Colombani O, O'Reilly RK | Polymer chemistry | 26918033 | Polym Chem | 2016 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/26918033 |
Stimuli-responsive nanomaterials for biomedical applications. | Blum AP, Kammeyer JK, Rush AM, Callmann CE, Hahn ME, Gianneschi NC | Journal of the American Chemical Society | 25474531 | J Am Chem Soc | 2015 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/25474531 |
Biological stimuli and biomolecules in the assembly and manipulation of nanoscale polymeric particles. | Randolph LM, Chien MP, Gianneschi NC | Chemical science | 24353895 | Chem Sci | 2012 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/24353895 |
Nuclease-resistant DNA via high-density packing in polymeric micellar nanoparticle coronas. | Rush AM, Thompson MP, Tatro ET, Gianneschi NC | ACS nano | 23379679 | ACS Nano | 2013 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/23379679 |
Enzyme-directed assembly of a nanoparticle probe in tumor tissue. | Chien MP, Thompson MP, Barback CV, Ku TH, Hall DJ, Gianneschi NC | Advanced materials (Deerfield Beach, Fla.) | 23712821 | Adv Mater | 2013 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/23712821 |
Biosynthetic Polymers as Functional Materials. | Carlini AS, Adamiak L, Gianneschi NC | Macromolecules | 27375299 | Macromolecules | 2016 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/27375299 |
Polymerization of Protecting-Group-Free Peptides via ROMP. | Kammeyer JK, Blum AP, Adamiak L, Hahn ME, Gianneschi NC | Polymer chemistry | 24015154 | Polym Chem | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24015154 |
Labelling Polymers and Micellar Nanoparticles via Initiation, Propagation and Termination with ROMP. | Thompson MP, Randolph LM, James CR, Davalos AN, Hahn ME, Gianneschi NC | Polymer chemistry | 24855496 | Polym Chem | 2014 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/24855496 |
Enzyme-directed assembly of nanoparticles in tumors monitored by in vivo whole animal imaging and ex vivo super-resolution fluorescence imaging. | Chien MP, Carlini AS, Hu D, Barback CV, Rush AM, Hall DJ, Orr G, Gianneschi NC | Journal of the American Chemical Society | 24308273 | J Am Chem Soc | 2013 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/24308273 |
Dynamics of soft nanomaterials captured by transmission electron microscopy in liquid water. | Proetto MT, Rush AM, Chien MP, Abellan Baeza P, Patterson JP, Thompson MP, Olson NH, Moore CE, Rheingold AL, Andolina C, Millstone J, Howell SB, Browning ND, Evans JE, Gianneschi NC | Journal of the American Chemical Society | 24422495 | J Am Chem Soc | 2014 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/24422495 |
Cellular Delivery of Nanoparticles Revealed with Combined Optical and Isotopic Nanoscopy. | Proetto MT, Anderton CR, Hu D, Szymanski CJ, Zhu Z, Patterson JP, Kammeyer JK, Nilewski LG, Rush AM, Bell NC, Evans JE, Orr G, Howell SB, Gianneschi NC | ACS nano | 27022832 | ACS Nano | 2016 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/27022832 |
Activating Peptides for Cellular Uptake via Polymerization into High Density Brushes. | Blum AP, Kammeyer JK, Gianneschi NC | Chemical science | 26925209 | Chem Sci | 2016 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/26925209 |
Peptides displayed as high density brush polymers resist proteolysis and retain bioactivity. | Blum AP, Kammeyer JK, Yin J, Crystal DT, Rush AM, Gilson MK, Gianneschi NC | Journal of the American Chemical Society | 25314576 | J Am Chem Soc | 2014 Oct 29 | https://www.ncbi.nlm.nih.gov/pubmed/25314576 |
Characterization of a large human transgene following invasin-mediated delivery in a bacterial artificial chromosome. | Gillen AE, Lucas CA, Haussecker PL, Kosak ST, Harris A | Chromosoma | 23749207 | Chromosoma | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23749207 |
Topologically associated domains enriched for lineage-specific genes reveal expression-dependent nuclear topologies during myogenesis. | Neems DS, Garza-Gongora AG, Smith ED, Kosak ST | Proceedings of the National Academy of Sciences of the United States of America | 26957603 | Proc Natl Acad Sci U S A | 2016 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/26957603 |
A beginning of the end: new insights into the functional organization of telomeres. | Wood AM, Laster K, Rice EL, Kosak ST | Nucleus (Austin, Tex.) | 25961132 | Nucleus | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25961132 |
Architectural proteins CTCF and cohesin have distinct roles in modulating the higher order structure and expression of the CFTR locus. | Gosalia N, Neems D, Kerschner JL, Kosak ST, Harris A | Nucleic acids research | 25081205 | Nucleic Acids Res | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25081205 |
Clinical Epigenetic Therapies Disrupt Sex Chromosome Dosage Compensation in Human Female Cells. | Laskowski AI, Fanslow DA, Smith ED, Kosak ST | Gender and the genome | 30899898 | Gend Genome | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30899898 |
Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus. | Yang R, Kerschner JL, Gosalia N, Neems D, Gorsic LK, Safi A, Crawford GE, Kosak ST, Leir SH, Harris A | Nucleic acids research | 26673704 | Nucleic Acids Res | 2016 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/26673704 |
Varying levels of X chromosome coalescence in female somatic cells alters the balance of X-linked dosage compensation and is implicated in female-dominant systemic lupus erythematosus. | Laskowski AI, Neems DS, Laster K, Strojny-Okyere C, Rice EL, Konieczna IM, Voss JH, Mathew JM, Leventhal JR, Ramsey-Goldman R, Smith ED, Kosak ST | Scientific reports | 31142749 | Sci Rep | 2019 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/31142749 |
A Crowdsourced nucleus: understanding nuclear organization in terms of dynamically networked protein function. | Wood AM, Garza-Gongora AG, Kosak ST | Biochimica et biophysica acta | 24412853 | Biochim Biophys Acta | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24412853 |
Interstitial telomeric loops and implications of the interaction between TRF2 and lamin A/C. | Smith ED, Garza-Gongora AG, MacQuarrie KL, Kosak ST | Differentiation; research in biological diversity | 29979997 | Differentiation | 2018 Jul-Aug | https://www.ncbi.nlm.nih.gov/pubmed/29979997 |
TRF2 and lamin A/C interact to facilitate the functional organization of chromosome ends. | Wood AM, Rendtlew Danielsen JM, Lucas CA, Rice EL, Scalzo D, Shimi T, Goldman RD, Smith ED, Le Beau MM, Kosak ST | Nature communications | 25399868 | Nat Commun | 2014 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/25399868 |
Analysis of a high-throughput cone-and-plate apparatus for the application of defined spatiotemporal flow to cultured cells. | Spruell C, Baker AB | Biotechnology and bioengineering | 23280552 | Biotechnol Bioeng | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23280552 |
Murine model of femoral artery wire injury with implantation of a perivascular drug delivery patch. | Le V, Johnson CG, Lee JD, Baker AB | Journal of visualized experiments : JoVE | 25742368 | J Vis Exp | 2015 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/25742368 |
Loss of syndecan-1 induces a pro-inflammatory phenotype in endothelial cells with a dysregulated response to atheroprotective flow. | Voyvodic PL, Min D, Liu R, Williams E, Chitalia V, Dunn AK, Baker AB | The Journal of biological chemistry | 24554698 | J Biol Chem | 2014 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/24554698 |
Syndecan-4 enhances PDGF-BB activity in diabetic wound healing. | Das S, Majid M, Baker AB | Acta biomaterialia | 27381525 | Acta Biomater | 2016 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/27381525 |
Syndecan-1 in mechanosensing of nanotopological cues in engineered materials. | Le V, Lee J, Chaterji S, Spencer A, Liu YL, Kim P, Yeh HC, Kim DH, Baker AB | Biomaterials | 29156422 | Biomaterials | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29156422 |
Syndecan-1 regulates vascular smooth muscle cell phenotype. | Chaterji S, Lam CH, Ho DS, Proske DC, Baker AB | PloS one | 24587062 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24587062 |
Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. | Koskinas KC, Sukhova GK, Baker AB, Papafaklis MI, Chatzizisis YS, Coskun AU, Quillard T, Jonas M, Maynard C, Antoniadis AP, Shi GP, Libby P, Edelman ER, Feldman CL, Stone PH | Arteriosclerosis, thrombosis, and vascular biology | 23640495 | Arterioscler Thromb Vasc Biol | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23640495 |
Syndecan-4 Enhances Therapeutic Angiogenesis after Hind Limb Ischemia in Mice with Type 2 Diabetes. | Das S, Monteforte AJ, Singh G, Majid M, Sherman MB, Dunn AK, Baker AB | Advanced healthcare materials | 26891081 | Adv Healthc Mater | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26891081 |
A novel system for studying mechanical strain waveform-dependent responses in vascular smooth muscle cells. | Lee J, Wong M, Smith Q, Baker AB | Lab on a chip | 24096612 | Lab Chip | 2013 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/24096612 |
(*) Glioblastoma Exosomes for Therapeutic Angiogenesis in Peripheral Ischemia. | Monteforte A, Lam B, Sherman MB, Henderson K, Sligar AD, Spencer A, Tang B, Dunn AK, Baker AB | Tissue engineering. Part A | 28699397 | Tissue Eng Part A | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28699397 |
Synergistic effect of local endothelial shear stress and systemic hypercholesterolemia on coronary atherosclerotic plaque progression and composition in pigs. | Koskinas KC, Chatzizisis YS, Papafaklis MI, Coskun AU, Baker AB, Jarolim P, Antoniadis A, Edelman ER, Stone PH, Feldman CL | International journal of cardiology | 24148915 | Int J Cardiol | 2013 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/24148915 |
The role of scaffold microarchitecture in engineering endothelial cell immunomodulation. | Indolfi L, Baker AB, Edelman ER | Biomaterials | 22796162 | Biomaterials | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22796162 |
A multichannel dampened flow system for studies on shear stress-mediated mechanotransduction. | Voyvodic PL, Min D, Baker AB | Lab on a chip | 22836694 | Lab Chip | 2012 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/22836694 |
Glypican-1 nanoliposomes for potentiating growth factor activity in therapeutic angiogenesis. | Monteforte AJ, Lam B, Das S, Mukhopadhyay S, Wright CS, Martin PE, Dunn AK, Baker AB | Biomaterials | 27101205 | Biomaterials | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27101205 |
Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle. | Jang E, Albadawi H, Watkins MT, Edelman ER, Baker AB | Proceedings of the National Academy of Sciences of the United States of America | 22307630 | Proc Natl Acad Sci U S A | 2012 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/22307630 |
Overcoming disease-induced growth factor resistance in therapeutic angiogenesis using recombinant co-receptors delivered by a liposomal system. | Das S, Singh G, Baker AB | Biomaterials | 24138828 | Biomaterials | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24138828 |
Syndesome Therapeutics for Enhancing Diabetic Wound Healing. | Das S, Singh G, Majid M, Sherman MB, Mukhopadhyay S, Wright CS, Martin PE, Dunn AK, Baker AB | Advanced healthcare materials | 27385307 | Adv Healthc Mater | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27385307 |
Optimized design of a hyperflexible sieve electrode to enhance neurovascular regeneration for a peripheral neural interface. | Veith A, Li X, Modi H, Abbaspour A, Luan L, Xie C, Baker AB | Biomaterials | 34147716 | Biomaterials | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34147716 |
Synergistic effects of matrix nanotopography and stiffness on vascular smooth muscle cell function. | Chaterji S, Kim P, Choe SH, Tsui JH, Lam CH, Ho DS, Baker AB, Kim DH | Tissue engineering. Part A | 24694244 | Tissue Eng Part A | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24694244 |
High Throughput Label Free Measurement of Cancer Cell Adhesion Kinetics Under Hemodynamic Flow. | Spencer A, Baker AB | Scientific reports | 26816215 | Sci Rep | 2016 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/26816215 |
A high-throughput mechanofluidic screening platform for investigating tumor cell adhesion during metastasis. | Spencer A, Spruell C, Nandi S, Wong M, Creixell M, Baker AB | Lab on a chip | 26584160 | Lab Chip | 2016 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/26584160 |
Computational analysis of fluid flow within a device for applying biaxial strain to cultured cells. | Lee J, Baker AB | Journal of biomechanical engineering | 25611013 | J Biomech Eng | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25611013 |
Heparanase regulates thrombosis in vascular injury and stent-induced flow disturbance. | Baker AB, Gibson WJ, Kolachalama VB, Golomb M, Indolfi L, Spruell C, Zcharia E, Vlodavsky I, Edelman ER | Journal of the American College of Cardiology | 22516446 | J Am Coll Cardiol | 2012 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/22516446 |
Nonlinear scaling of surface water diffusion with bulk water viscosity of crowded solutions. | Franck JM, Scott JA, Han S | Journal of the American Chemical Society | 23347324 | J Am Chem Soc | 2013 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/23347324 |
Specific ions modulate diffusion dynamics of hydration water on lipid membrane surfaces. | Song J, Franck J, Pincus P, Kim MW, Han S | Journal of the American Chemical Society | 24456096 | J Am Chem Soc | 2014 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/24456096 |
DMSO induces dehydration near lipid membrane surfaces. | Cheng CY, Song J, Pas J, Meijer LH, Han S | Biophysical journal | 26200868 | Biophys J | 2015 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/26200868 |
Quantitative cw Overhauser effect dynamic nuclear polarization for the analysis of local water dynamics. | Franck JM, Pavlova A, Scott JA, Han S | Progress in nuclear magnetic resonance spectroscopy | 24083461 | Prog Nucl Magn Reson Spectrosc | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24083461 |
Intrinsic surface-drying properties of bioadhesive proteins. | Akdogan Y, Wei W, Huang KY, Kageyama Y, Danner EW, Miller DR, Martinez Rodriguez NR, Waite JH, Han S | Angewandte Chemie (International ed. in English) | 25168789 | Angew Chem Int Ed Engl | 2014 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/25168789 |
Overhauser Dynamic Nuclear Polarization-Enhanced NMR Relaxometry. | Franck JM, Kausik R, Han S | Microporous and mesoporous materials : the official journal of the International Zeolite Association | 23837010 | Microporous Mesoporous Mater | 2013 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/23837010 |
Tau Aggregation Propensity Engrained in Its Solution State. | Eschmann NA, Do TD, LaPointe NE, Shea JE, Feinstein SC, Bowers MT, Han S | The journal of physical chemistry. B | 26484390 | J Phys Chem B | 2015 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/26484390 |
Asymmetric collapse in biomimetic complex coacervates revealed by local polymer and water dynamics. | Ortony JH, Hwang DS, Franck JM, Waite JH, Han S | Biomacromolecules | 23540713 | Biomacromolecules | 2013 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/23540713 |
Hydration dynamics as an intrinsic ruler for refining protein structure at lipid membrane interfaces. | Cheng CY, Varkey J, Ambroso MR, Langen R, Han S | Proceedings of the National Academy of Sciences of the United States of America | 24082088 | Proc Natl Acad Sci U S A | 2013 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/24082088 |
Quantitative analysis of molecular transport across liposomal bilayer by J-mediated 13C Overhauser dynamic nuclear polarization. | Cheng CY, Goor OJ, Han S | Analytical chemistry | 23072518 | Anal Chem | 2012 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/23072518 |
Correlating steric hydration forces with water dynamics through surface force and diffusion NMR measurements in a lipid-DMSO-H2O system. | Schrader AM, Donaldson SH Jr, Song J, Cheng CY, Lee DW, Han S, Israelachvili JN | Proceedings of the National Academy of Sciences of the United States of America | 26261313 | Proc Natl Acad Sci U S A | 2015 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/26261313 |
Cholesterol enhances surface water diffusion of phospholipid bilayers. | Cheng CY, Olijve LL, Kausik R, Han S | The Journal of chemical physics | 25494784 | J Chem Phys | 2014 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/25494784 |
Functional consequences of the oligomeric assembly of proteorhodopsin. | Hussain S, Kinnebrew M, Schonenbach NS, Aye E, Han S | Journal of molecular biology | 25597999 | J Mol Biol | 2015 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/25597999 |
Dynamic nuclear polarization methods in solids and solutions to explore membrane proteins and membrane systems. | Cheng CY, Han S | Annual review of physical chemistry | 23331309 | Annu Rev Phys Chem | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23331309 |
Probing water density and dynamics in the chaperonin GroEL cavity. | Franck JM, Sokolovski M, Kessler N, Matalon E, Gordon-Grossman M, Han SI, Goldfarb D, Horovitz A | Journal of the American Chemical Society | 24888581 | J Am Chem Soc | 2014 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/24888581 |
Nanometer-scale water- and proton-diffusion heterogeneities across water channels in polymer electrolyte membranes. | Song J, Han OH, Han S | Angewandte Chemie (International ed. in English) | 25630609 | Angew Chem Int Ed Engl | 2015 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/25630609 |
Ion specific effects: decoupling ion-ion and ion-water interactions. | Song J, Kang TH, Kim MW, Han S | Physical chemistry chemical physics : PCCP | 25761273 | Phys Chem Chem Phys | 2015 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/25761273 |
Anomalously Rapid Hydration Water Diffusion Dynamics Near DNA Surfaces. | Franck JM, Ding Y, Stone K, Qin PZ, Han S | Journal of the American Chemical Society | 26256693 | J Am Chem Soc | 2015 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/26256693 |
Temporal and fluoride control of secondary metabolism regulates cellular organofluorine biosynthesis. | Walker MC, Wen M, Weeks AM, Chang MC | ACS chemical biology | 22769062 | ACS Chem Biol | 2012 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/22769062 |
Molecular recognition of fluorine impacts substrate selectivity in the fluoroacetyl-CoA thioesterase FlK. | Weeks AM, Keddie NS, Wadoux RD, O'Hagan D, Chang MC | Biochemistry | 24635371 | Biochemistry | 2014 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24635371 |
Synthetic biology approaches to fluorinated polyketides. | Thuronyi BW, Chang MC | Accounts of chemical research | 25719427 | Acc Chem Res | 2015 Mar 17 | https://www.ncbi.nlm.nih.gov/pubmed/25719427 |
Editorial overview: Opportunities and challenges in synthetic biology. | Chang MC, Zhao H | Current opinion in chemical biology | 26456417 | Curr Opin Chem Biol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26456417 |
Natural and engineered biosynthesis of fluorinated natural products. | Walker MC, Chang MC | Chemical Society reviews | 24776946 | Chem Soc Rev | 2014 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/24776946 |
Catalytic control of enzymatic fluorine specificity. | Weeks AM, Chang MC | Proceedings of the National Academy of Sciences of the United States of America | 23150553 | Proc Natl Acad Sci U S A | 2012 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/23150553 |
Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways. | Walker MC, Thuronyi BW, Charkoudian LK, Lowry B, Khosla C, Chang MC | Science (New York, N.Y.) | 24009388 | Science | 2013 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/24009388 |
Constructing de novo biosynthetic pathways for chemical synthesis inside living cells. | Weeks AM, Chang MC | Biochemistry | 21591680 | Biochemistry | 2011 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/21591680 |
Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity. | Weeks AM, Coyle SM, Jinek M, Doudna JA, Chang MC | Biochemistry | 20836570 | Biochemistry | 2010 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/20836570 |
Elucidating the mechanism of fluorinated extender unit loading for improved production of fluorine-containing polyketides. | Ad O, Thuronyi BW, Chang MC | Proceedings of the National Academy of Sciences of the United States of America | 28096394 | Proc Natl Acad Sci U S A | 2017 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/28096394 |
Fluorophore and dye-assisted dispersion of carbon nanotubes in aqueous solution. | Koh B, Kim G, Yoon HK, Park JB, Kopelman R, Cheng W | Langmuir : the ACS journal of surfaces and colloids | 22812904 | Langmuir | 2012 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/22812904 |
Detection of single fluorescent proteins inside eukaryotic cells using two-photon fluorescence. | Hou X, Cheng W | Biomedical optics express | 22312586 | Biomed Opt Express | 2012 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/22312586 |
Mechanisms of carbon nanotube aggregation and the reversion of carbon nanotube aggregates in aqueous medium. | Koh B, Cheng W | Langmuir : the ACS journal of surfaces and colloids | 25144606 | Langmuir | 2014 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/25144606 |
Mechanisms of HCV NS3 helicase monitored by optical tweezers. | Cheng W | Methods in molecular biology (Clifton, N.J.) | 25579590 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25579590 |
The Density Code for the Development of a Vaccine? | Cheng W | Journal of pharmaceutical sciences | 27649885 | J Pharm Sci | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27649885 |
Microfluidic-based high-throughput optical trapping of nanoparticles. | Kotnala A, Zheng Y, Fu J, Cheng W | Lab on a chip | 28561826 | Lab Chip | 2017 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/28561826 |
Optical manipulation of a single human virus for study of viral-cell interactions. | Hou X, DeSantis MC, Tian C, Cheng W | Proceedings of SPIE--the International Society for Optical Engineering | 27746582 | Proc SPIE Int Soc Opt Eng | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27746582 |
Reversible aggregation of HIV-1 Gag proteins mediated by nucleic acids. | Chen Z, Cheng W | Biochemical and biophysical research communications | 27965093 | Biochem Biophys Res Commun | 2017 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/27965093 |
Optical trapping of individual human immunodeficiency viruses in culture fluid reveals heterogeneity with single-molecule resolution. | Pang Y, Song H, Kim JH, Hou X, Cheng W | Nature nanotechnology | 25038779 | Nat Nanotechnol | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/25038779 |
Probability of Immobilization on Host Cell Surface Regulates Viral Infectivity. | DeSantis MC, Tian C, Kim JH, Austin JL, Cheng W | Physical review letters | 33016741 | Phys Rev Lett | 2020 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/33016741 |
Optimized Infectivity of the Cell-Free Single-Cycle Human Immunodeficiency Viruses Type 1 (HIV-1) and Its Restriction by Host Cells. | Kim JH, Song H, Austin JL, Cheng W | PloS one | 23825637 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23825637 |
Label-free detection and manipulation of single biological nanoparticles. | DeSantis MC, Cheng W | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 26846164 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26846164 |
Using optical trap to measure the refractive index of a single animal virus in culture fluid with high precision. | Pang Y, Song H, Cheng W | Biomedical optics express | 27231613 | Biomed Opt Express | 2016 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/27231613 |
Dynasore inhibition on productive infection of HIV-1 in commonly used cell lines is independent of transferrin endocytosis. | Song H, DeSantis M, Tian C, Cheng W | Matters | 31058179 | Matters (Zur) | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/31058179 |
Quantitation and Stability of Protein Conjugation on Liposomes for Controlled Density of Surface Epitopes. | Chen Z, Moon JJ, Cheng W | Bioconjugate chemistry | 29528624 | Bioconjug Chem | 2018 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/29528624 |
Step detection in single-molecule real time trajectories embedded in correlated noise. | Arunajadai SG, Cheng W | PloS one | 23533612 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23533612 |
Quantitative Correlation between Infectivity and Gp120 Density on HIV-1 Virions Revealed by Optical Trapping Virometry. | DeSantis MC, Kim JH, Song H, Klasse PJ, Cheng W | The Journal of biological chemistry | 27129237 | J Biol Chem | 2016 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/27129237 |
The Single-Molecule Centroid Localization Algorithm Improves the Accuracy of Fluorescence Binding Assays. | Hua B, Wang Y, Park S, Han KY, Singh D, Kim JH, Cheng W, Ha T | Biochemistry | 29457977 | Biochemistry | 2018 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/29457977 |
Electrowetting-driven variable-focus microlens on flexible surfaces. | Li C, Jiang H | Applied physics letters | 22904571 | Appl Phys Lett | 2012 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/22904571 |
One-step femtosecond laser patterning of light-trapping structure on dye-sensitized solar cell photoelectrodes†. | Zhang X, Liu H, Huang X, Jiang H | Journal of materials chemistry. C | 26113977 | J Mater Chem C Mater | 2015 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/26113977 |
Photovoltaically Self-Charging Cells with WO(3)·H(2)O/CNTs/PVDF Composite. | Huang X, Zhang X, Jiang H | RSC advances | 27774146 | RSC Adv | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27774146 |
Dye-sensitized solar cell with energy storage function through PVDF/ZnO nanocomposite counter electrode. | Zhang X, Huang X, Li C, Jiang H | Advanced materials (Deerfield Beach, Fla.) | 23740719 | Adv Mater | 2013 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/23740719 |
Scattering-layer-induced energy storage function in polymer-based quasi-solid-state dye-sensitized solar cells. | Zhang X, Jiang H | Applied physics letters | 25829547 | Appl Phys Lett | 2015 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/25829547 |
Artificial eye for scotopic vision with bioinspired all-optical photosensitivity enhancer. | Liu H, Huang Y, Jiang H | Proceedings of the National Academy of Sciences of the United States of America | 26976565 | Proc Natl Acad Sci U S A | 2016 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/26976565 |
Tunable dielectric liquid lens on flexible substrate. | Lu YS, Tu H, Xu Y, Jiang H | Applied physics letters | 24493877 | Appl Phys Lett | 2013 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/24493877 |
Actuators based on liquid crystalline elastomer materials. | Jiang H, Li C, Huang X | Nanoscale | 23648966 | Nanoscale | 2013 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/23648966 |
Design and fabrication of an electrohydrodynamically actuated microlens with areal density modulated electrodes. | Ashtiani AO, Jiang H | Journal of micromechanics and microengineering : structures, devices, and systems | 32773966 | J Micromech Microeng | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32773966 |
A Liquid Optical Phase Shifter with an Embedded Electrowetting Actuator. | Ashtiani AO, Jiang H | Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems | 29038640 | J Microelectromech Syst | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29038640 |
High Performance All-Solid-State Flexible Micro-Pseudocapacitor Based on Hierarchically Nanostructured Tungsten Trioxide Composite. | Huang X, Liu H, Zhang X, Jiang H | ACS applied materials & interfaces | 26618406 | ACS Appl Mater Interfaces | 2015 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/26618406 |
Lateral dye-sensitized microscale solar cells via femtosecond laser patterning. | Zhang X, Huang Y, Hao B, Hewei L, Huang X, Jiang H | Advanced materials technologies | 31341947 | Adv Mater Technol | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31341947 |
Double Sided-Design of Electrodes Driving Tunable Dielectrophoretic Miniature Lens. | Almoallem Y, Jiang H | Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems | 29606846 | J Microelectromech Syst | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29606846 |
Liquid Tunable Microlenses based on MEMS techniques. | Zeng X, Jiang H | Journal of physics D: Applied physics | 24163480 | J Phys D Appl Phys | 2013 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/24163480 |
Recovering degraded quasi-solid-state dye-sensitized solar cells by applying electrical pulses. | Zhang X, Huang X, Jiang H | Physical chemistry chemical physics : PCCP | 23545782 | Phys Chem Chem Phys | 2013 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/23545782 |
Energy Storage via Polyvinylidene Fluoride Dielectric on the Counterelectrode of Dye-Sensitized Solar Cells. | Huang X, Zhang X, Jiang H | Journal of power sources | 24327797 | J Power Sources | 2014 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/24327797 |
Remote Axial Tuning in Microscopy Utilizing Hydrogel-Driven Tunable Liquid Lens. | Kanhere A, Lin G, Jiang H | Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems | 31983867 | J Microelectromech Syst | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31983867 |
Fabrication and Characterization of Flexible Electrowetting on Dielectrics (EWOD) Microlens. | Li C, Jiang H | Micromachines | 25360324 | Micromachines (Basel) | 2014 Jul 4 | https://www.ncbi.nlm.nih.gov/pubmed/25360324 |
Tight regulation of plant immune responses by combining promoter and suicide exon elements. | Gonzalez TL, Liang Y, Nguyen BN, Staskawicz BJ, Loqué D, Hammond MC | Nucleic acids research | 26138488 | Nucleic Acids Res | 2015 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/26138488 |
Structural basis for molecular discrimination by a 3',3'-cGAMP sensing riboswitch. | Ren A, Wang XC, Kellenberger CA, Rajashankar KR, Jones RA, Hammond MC, Patel DJ | Cell reports | 25818298 | Cell Rep | 2015 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/25818298 |
Chemiluminescent Biosensors for Detection of Second Messenger Cyclic di-GMP. | Dippel AB, Anderson WA, Evans RS, Deutsch S, Hammond MC | ACS chemical biology | 29466657 | ACS Chem Biol | 2018 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/29466657 |
Structure-guided design of fluorescent S-adenosylmethionine analogs for a high-throughput screen to target SAM-I riboswitch RNAs. | Hickey SF, Hammond MC | Chemistry & biology | 24560607 | Chem Biol | 2014 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/24560607 |
Live Flow Cytometry Analysis of c-di-GMP Levels in Single Cell Populations. | Yeo J, Wang XC, Hammond MC | Methods in molecular biology (Clifton, N.J.) | 28889290 | Methods Mol Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28889290 |
In Vitro and In Vivo Enzyme Activity Screening via RNA-Based Fluorescent Biosensors for S-Adenosyl-l-homocysteine (SAH). | Su Y, Hickey SF, Keyser SG, Hammond MC | Journal of the American Chemical Society | 27191512 | J Am Chem Soc | 2016 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/27191512 |
Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-GMP (3', 3'-cGAMP). | Hallberg ZF, Wang XC, Wright TA, Nan B, Ad O, Yeo J, Hammond MC | Proceedings of the National Academy of Sciences of the United States of America | 26839412 | Proc Natl Acad Sci U S A | 2016 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/26839412 |
An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway. | Bose D, Su Y, Marcus A, Raulet DH, Hammond MC | Cell chemical biology | 27889408 | Cell Chem Biol | 2016 Dec 22 | https://www.ncbi.nlm.nih.gov/pubmed/27889408 |
GEMM-I riboswitches from Geobacter sense the bacterial second messenger cyclic AMP-GMP. | Kellenberger CA, Wilson SC, Hickey SF, Gonzalez TL, Su Y, Hallberg ZF, Brewer TF, Iavarone AT, Carlson HK, Hsieh YF, Hammond MC | Proceedings of the National Academy of Sciences of the United States of America | 25848022 | Proc Natl Acad Sci U S A | 2015 Apr 28 | https://www.ncbi.nlm.nih.gov/pubmed/25848022 |
Microfluidic screening of electrophoretic mobility shifts elucidates riboswitch binding function. | Karns K, Vogan JM, Qin Q, Hickey SF, Wilson SC, Hammond MC, Herr AE | Journal of the American Chemical Society | 23343213 | J Am Chem Soc | 2013 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/23343213 |
A minimalist biosensor: Quantitation of cyclic di-GMP using the conformational change of a riboswitch aptamer. | Kellenberger CA, Sales-Lee J, Pan Y, Gassaway MM, Herr AE, Hammond MC | RNA biology | 26114964 | RNA Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26114964 |
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING. | Diner EJ, Burdette DL, Wilson SC, Monroe KM, Kellenberger CA, Hyodo M, Hayakawa Y, Hammond MC, Vance RE | Cell reports | 23707065 | Cell Rep | 2013 May 30 | https://www.ncbi.nlm.nih.gov/pubmed/23707065 |
Next-generation RNA-based fluorescent biosensors enable anaerobic detection of cyclic di-GMP. | Wang XC, Wilson SC, Hammond MC | Nucleic acids research | 27382070 | Nucleic Acids Res | 2016 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/27382070 |
RNA-Based Fluorescent Biosensors for Live Cell Imaging of Second Messenger Cyclic di-AMP. | Kellenberger CA, Chen C, Whiteley AT, Portnoy DA, Hammond MC | Journal of the American Chemical Society | 25965978 | J Am Chem Soc | 2015 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/25965978 |
Live Cell Imaging Using Riboswitch-Spinach tRNA Fusions as Metabolite-Sensing Fluorescent Biosensors. | Kellenberger CA, Hallberg ZF, Hammond MC | Methods in molecular biology (Clifton, N.J.) | 25967055 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25967055 |
High-throughput electrophoretic mobility shift assays for quantitative analysis of molecular binding reactions. | Pan Y, Duncombe TA, Kellenberger CA, Hammond MC, Herr AE | Analytical chemistry | 25233437 | Anal Chem | 2014 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/25233437 |
Engineering and In Vivo Applications of Riboswitches. | Hallberg ZF, Su Y, Kitto RZ, Hammond MC | Annual review of biochemistry | 28375743 | Annu Rev Biochem | 2017 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/28375743 |
RNA-based fluorescent biosensors for live cell imaging of second messengers cyclic di-GMP and cyclic AMP-GMP. | Kellenberger CA, Wilson SC, Sales-Lee J, Hammond MC | Journal of the American Chemical Society | 23488798 | J Am Chem Soc | 2013 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/23488798 |
Nutritional control of epigenetic processes in yeast and human cells. | Sadhu MJ, Guan Q, Li F, Sales-Lee J, Iavarone AT, Hammond MC, Cande WZ, Rine J | Genetics | 23979574 | Genetics | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23979574 |
A neutral pH thermal hydrolysis method for quantification of structured RNAs. | Wilson SC, Cohen DT, Wang XC, Hammond MC | RNA (New York, N.Y.) | 24860014 | RNA | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24860014 |
In vitro analysis of riboswitch-Spinach aptamer fusions as metabolite-sensing fluorescent biosensors. | Kellenberger CA, Hammond MC | Methods in enzymology | 25605385 | Methods Enzymol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25605385 |
In Vivo Biochemistry: Single-Cell Dynamics of Cyclic Di-GMP in Escherichia coli in Response to Zinc Overload. | Yeo J, Dippel AB, Wang XC, Hammond MC | Biochemistry | 29052983 | Biochemistry | 2018 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/29052983 |
Designing fluorescent biosensors using circular permutations of riboswitches. | Truong J, Hsieh YF, Truong L, Jia G, Hammond MC | Methods (San Diego, Calif.) | 29458090 | Methods | 2018 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/29458090 |
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Gene duplication and co-evolution of G1/S transcription factor specificity in fungi are essential for optimizing cell fitness. | Hendler A, Medina EM, Kishkevich A, Abu-Qarn M, Klier S, Buchler NE, de Bruin RAM, Aharoni A | PLoS genetics | 28505153 | PLoS Genet | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28505153 |
BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells. | Gómez-Schiavon M, Chen LF, West AE, Buchler NE | Genome biology | 28870226 | Genome Biol | 2017 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/28870226 |
Epigenetic switching as a strategy for quick adaptation while attenuating biochemical noise. | Gómez-Schiavon M, Buchler NE | PLoS computational biology | 31658246 | PLoS Comput Biol | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31658246 |
Cell cycle Start is coupled to entry into the yeast metabolic cycle across diverse strains and growth rates. | Burnetti AJ, Aydin M, Buchler NE | Molecular biology of the cell | 26538026 | Mol Biol Cell | 2016 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/26538026 |
Redox rhythm reinforces the circadian clock to gate immune response. | Zhou M, Wang W, Karapetyan S, Mwimba M, Marqués J, Buchler NE, Dong X | Nature | 26098366 | Nature | 2015 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/26098366 |
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Measuring fast gene dynamics in single cells with time-lapse luminescence microscopy. | Mazo-Vargas A, Park H, Aydin M, Buchler NE | Molecular biology of the cell | 25232010 | Mol Biol Cell | 2014 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/25232010 |
Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes. | Chen LF, Lin YT, Gallegos DA, Hazlett MF, Gómez-Schiavon M, Yang MG, Kalmeta B, Zhou AS, Holtzman L, Gersbach CA, Grandl J, Buchler NE, West AE | Cell reports | 30699347 | Cell Rep | 2019 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/30699347 |
Different Mechanisms Confer Gradual Control and Memory at Nutrient- and Stress-Regulated Genes in Yeast. | Rienzo A, Poveda-Huertes D, Aydin S, Buchler NE, Pascual-Ahuir A, Proft M | Molecular and cellular biology | 26283730 | Mol Cell Biol | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26283730 |
Role of DNA binding sites and slow unbinding kinetics in titration-based oscillators. | Karapetyan S, Buchler NE | Physical review. E, Statistical, nonlinear, and soft matter physics | 26764732 | Phys Rev E Stat Nonlin Soft Matter Phys | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26764732 |
Programming stress-induced altruistic death in engineered bacteria. | Tanouchi Y, Pai A, Buchler NE, You L | Molecular systems biology | 23169002 | Mol Syst Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23169002 |
Punctuated evolution and transitional hybrid network in an ancestral cell cycle of fungi. | Medina EM, Turner JJ, Gordân R, Skotheim JM, Buchler NE | eLife | 27162172 | Elife | 2016 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/27162172 |
Efficient analysis of stochastic gene dynamics in the non-adiabatic regime using piecewise deterministic Markov processes. | Lin YT, Buchler NE | Journal of the Royal Society, Interface | 29386401 | J R Soc Interface | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29386401 |
RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity. | Pefanis E, Wang J, Rothschild G, Lim J, Kazadi D, Sun J, Federation A, Chao J, Elliott O, Liu ZP, Economides AN, Bradner JE, Rabadan R, Basu U | Cell | 25957685 | Cell | 2015 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/25957685 |
Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry. | Lim J, Giri PK, Kazadi D, Laffleur B, Zhang W, Grinstein V, Pefanis E, Brown LM, Ladewig E, Martin O, Chen Y, Rabadan R, Boyer F, Rothschild G, Cogné M, Pinaud E, Deng H, Basu U | Cell | 28431250 | Cell | 2017 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/28431250 |
E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells. | Sun J, Keim CD, Wang J, Kazadi D, Oliver PM, Rabadan R, Basu U | Genes & development | 23964096 | Genes Dev | 2013 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/23964096 |
Transcriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrity. | Sun J, Rothschild G, Pefanis E, Basu U | Transcription | 23584095 | Transcription | 2013 May-Jun | https://www.ncbi.nlm.nih.gov/pubmed/23584095 |
Regulation of AID, the B-cell genome mutator. | Keim C, Kazadi D, Rothschild G, Basu U | Genes & development | 23307864 | Genes Dev | 2013 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/23307864 |
RNA Exosome and Non-coding RNA-Coupled Mechanisms in AID-Mediated Genomic Alterations. | Laffleur B, Basu U, Lim J | Journal of molecular biology | 28069372 | J Mol Biol | 2017 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/28069372 |
Malaria-Induced B Cell Genomic Instability. | Rothschild G, von Krusenstiern AN, Basu U | Cell | 26276622 | Cell | 2015 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/26276622 |
Ubiquitination events that regulate recombination of immunoglobulin Loci gene segments. | Chao J, Rothschild G, Basu U | Frontiers in immunology | 24653725 | Front Immunol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24653725 |
RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome. | Pefanis E, Basu U | Advances in immunology | 26073986 | Adv Immunol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26073986 |
Transcriptomics Identify CD9 as a Marker of Murine IL-10-Competent Regulatory B Cells. | Sun J, Wang J, Pefanis E, Chao J, Rothschild G, Tachibana I, Chen JK, Ivanov II, Rabadan R, Takeda Y, Basu U | Cell reports | 26527007 | Cell Rep | 2015 Nov 10 | https://www.ncbi.nlm.nih.gov/pubmed/26527007 |
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The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity. | Rialdi A, Hultquist J, Jimenez-Morales D, Peralta Z, Campisi L, Fenouil R, Moshkina N, Wang ZZ, Laffleur B, Kaake RM, McGregor MJ, Haas K, Pefanis E, Albrecht RA, Pache L, Chanda S, Jen J, Ochando J, Byun M, Basu U, García-Sastre A, Krogan N, van Bakel H, Marazzi I | Cell | 28475896 | Cell | 2017 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/28475896 |
Lingering Questions about Enhancer RNA and Enhancer Transcription-Coupled Genomic Instability. | Rothschild G, Basu U | Trends in genetics : TIG | 28087167 | Trends Genet | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/28087167 |
Medical documentation in the electronic era. | Wang CJ | JAMA | 23188023 | JAMA | 2012 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/23188023 |
The HIPAA conundrum in the era of mobile health and communications. | Wang CJ, Huang DJ | JAMA | 23978879 | JAMA | 2013 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/23978879 |
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Activation of Xist by an evolutionarily conserved function of KDM5C demethylase. | Samanta MK, Gayen S, Harris C, Maclary E, Murata-Nakamura Y, Malcore RM, Porter RS, Garay PM, Vallianatos CN, Samollow PB, Iwase S, Kalantry S | Nature communications | 35545632 | Nat Commun | 2022 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/35545632 |
A Primary Role for the Tsix lncRNA in Maintaining Random X-Chromosome Inactivation. | Gayen S, Maclary E, Buttigieg E, Hinten M, Kalantry S | Cell reports | 25981039 | Cell Rep | 2015 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/25981039 |
Experimental Analysis of Imprinted Mouse X-Chromosome Inactivation. | Cloutier M, Harris C, Gayen S, Maclary E, Kalantry S | Methods in molecular biology (Clifton, N.J.) | 30218368 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30218368 |
Sex-specific silencing of X-linked genes by Xist RNA. | Gayen S, Maclary E, Hinten M, Kalantry S | Proceedings of the National Academy of Sciences of the United States of America | 26739568 | Proc Natl Acad Sci U S A | 2016 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/26739568 |
MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency. | Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Karatas H, Liu L, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y | Cell stem cell | 26996599 | Cell Stem Cell | 2016 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/26996599 |
Regulation of Sex-biased Gene Expression by the Ancestral X-Y Chromosomal Gene Pair Kdm5c-Kdm5d. | Malcore RM, Samanta MK, Kalantry S, Iwase S | bioRxiv : the preprint server for biology | 39484414 | bioRxiv | 2024 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/39484414 |
Long nonoding RNAs in the X-inactivation center. | Maclary E, Hinten M, Harris C, Kalantry S | Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology | 24297756 | Chromosome Res | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24297756 |
Functional Dissection of the m6A RNA Modification. | Huisman B, Manske G, Carney S, Kalantry S | Trends in biochemical sciences | 28063638 | Trends Biochem Sci | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/28063638 |
Highly Resolved Detection of Long Non-coding RNAs In Situ. | Trotter M, Harris C, Cloutier M, Samanta M, Kalantry S | Methods in molecular biology (Clifton, N.J.) | 34417748 | Methods Mol Biol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34417748 |
Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells. | Taniguchi K, Shao Y, Townshend RF, Tsai YH, DeLong CJ, Lopez SA, Gayen S, Freddo AM, Chue DJ, Thomas DJ, Spence JR, Margolis B, Kalantry S, Fu J, O'Shea KS, Gumucio DL | Stem cell reports | 26626176 | Stem Cell Reports | 2015 Dec 8 | https://www.ncbi.nlm.nih.gov/pubmed/26626176 |
Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis. | Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L, Rao A | Proceedings of the National Academy of Sciences of the United States of America | 26199412 | Proc Natl Acad Sci U S A | 2015 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/26199412 |
Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2. | Harris C, Cloutier M, Trotter M, Hinten M, Gayen S, Du Z, Xie W, Kalantry S | eLife | 30938678 | Elife | 2019 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/30938678 |
Chromatin-enriched lncRNAs: a novel class of enhancer RNAs. | Gayen S, Kalantry S | Nature structural & molecular biology | 28686230 | Nat Struct Mol Biol | 2017 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/28686230 |
Differentiation-dependent requirement of Tsix long non-coding RNA in imprinted X-chromosome inactivation. | Maclary E, Buttigieg E, Hinten M, Gayen S, Harris C, Sarkar MK, Purushothaman S, Kalantry S | Nature communications | 24979243 | Nat Commun | 2014 Jun 30 | https://www.ncbi.nlm.nih.gov/pubmed/24979243 |
Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. | Jiao B, Ma H, Shokhirev MN, Drung A, Yang Q, Shin J, Lu S, Byron M, Kalantry S, Mercurio AM, Lawrence JB, Hoffmann A, Bach I | Cell | 22541433 | Cell | 2012 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/22541433 |
PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes. | Kang J, Kalantry S, Rao A | Cell research | 22868271 | Cell Res | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22868271 |
A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance. | Ku CJ, Lim KC, Kalantry S, Maillard I, Engel JD, Hosoya T | Genes & development | 26385963 | Genes Dev | 2015 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/26385963 |
Mary Lyon: A Tribute. | Kalantry S, Mueller JL | American journal of human genetics | 26713337 | Am J Hum Genet | 2015 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/26713337 |
The central role of EED in the orchestration of polycomb group complexes. | Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, Poliakov A, Yocum AK, Li Y, Chen W, Cao X, Jiang X, Dahiya A, Harris C, Feng FY, Kalantry S, Qin ZS, Dhanasekaran SM, Chinnaiyan AM | Nature communications | 24457600 | Nat Commun | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24457600 |
An Xist-activating antisense RNA required for X-chromosome inactivation. | Sarkar MK, Gayen S, Kumar S, Maclary E, Buttigieg E, Hinten M, Kumari A, Harris C, Sado T, Kalantry S | Nature communications | 26477563 | Nat Commun | 2015 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/26477563 |
Visualizing Long Noncoding RNAs on Chromatin. | Hinten M, Maclary E, Gayen S, Harris C, Kalantry S | Methods in molecular biology (Clifton, N.J.) | 26721489 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26721489 |
PRC2 represses transcribed genes on the imprinted inactive X chromosome in mice. | Maclary E, Hinten M, Harris C, Sethuraman S, Gayen S, Kalantry S | Genome biology | 28468635 | Genome Biol | 2017 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/28468635 |
An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells. | Taniguchi K, Shao Y, Townshend RF, Cortez CL, Harris CE, Meshinchi S, Kalantry S, Fu J, O'Shea KS, Gumucio DL | The Journal of cell biology | 29021220 | J Cell Biol | 2017 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/29021220 |
Phonetic feature encoding in human superior temporal gyrus. | Mesgarani N, Cheung C, Johnson K, Chang EF | Science (New York, N.Y.) | 24482117 | Science | 2014 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/24482117 |
The Control of Vocal Pitch in Human Laryngeal Motor Cortex. | Dichter BK, Breshears JD, Leonard MK, Chang EF | Cell | 29958109 | Cell | 2018 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/29958109 |
Encoding of Articulatory Kinematic Trajectories in Human Speech Sensorimotor Cortex. | Chartier J, Anumanchipalli GK, Johnson K, Chang EF | Neuron | 29779940 | Neuron | 2018 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/29779940 |
Real-time classification of auditory sentences using evoked cortical activity in humans. | Moses DA, Leonard MK, Chang EF | Journal of neural engineering | 29378977 | J Neural Eng | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29378977 |
Control of spoken vowel acoustics and the influence of phonetic context in human speech sensorimotor cortex. | Bouchard KE, Chang EF | The Journal of neuroscience : the official journal of the Society for Neuroscience | 25232105 | J Neurosci | 2014 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/25232105 |
Are preoperative chlorhexidine gluconate showers associated with a reduction in surgical site infection following craniotomy? A retrospective cohort analysis of 3126 surgical procedures. | Ammanuel SG, Edwards CS, Chan AK, Mummaneni PV, Kidane J, Vargas E, D'Souza S, Nichols AD, Sankaran S, Abla AA, Aghi MK, Chang EF, Hervey-Jumper SL, Kunwar S, Larson PS, Lawton MT, Starr PA, Theodosopoulos PV, Berger MS, McDermott MW | Journal of neurosurgery | 33930864 | J Neurosurg | 2021 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/33930864 |
Inhibitory control of speech production in the human premotor frontal cortex. | Zhao L, Silva AB, Kurteff GL, Chang EF | Nature human behaviour | 40033133 | Nat Hum Behav | 2025 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/40033133 |
Speech map in the human ventral sensory-motor cortex. | Conant D, Bouchard KE, Chang EF | Current opinion in neurobiology | 24492080 | Curr Opin Neurobiol | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24492080 |
Persistent neuronal activity in human prefrontal cortex links perception and action. | Haller M, Case J, Crone NE, Chang EF, King-Stephens D, Laxer KD, Weber PB, Parvizi J, Knight RT, Shestyuk AY | Nature human behaviour | 29963646 | Nat Hum Behav | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29963646 |
Contemporary model of language organization: an overview for neurosurgeons. | Chang EF, Raygor KP, Berger MS | Journal of neurosurgery | 25423277 | J Neurosurg | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25423277 |
The peri-Sylvian cortical network underlying single word repetition revealed by electrocortical stimulation and direct neural recordings. | Leonard MK, Cai R, Babiak MC, Ren A, Chang EF | Brain and language | 27450996 | Brain Lang | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27450996 |
The influence of lexical statistics on temporal lobe cortical dynamics during spoken word listening. | Cibelli ES, Leonard MK, Johnson K, Chang EF | Brain and language | 26072003 | Brain Lang | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26072003 |
Neural speech recognition: continuous phoneme decoding using spatiotemporal representations of human cortical activity. | Moses DA, Mesgarani N, Leonard MK, Chang EF | Journal of neural engineering | 27484713 | J Neural Eng | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27484713 |
Cortical Encoding of Manual Articulatory and Linguistic Features in American Sign Language. | Leonard MK, Lucas B, Blau S, Corina DP, Chang EF | Current biology : CB | 32888480 | Curr Biol | 2020 Nov 16 | https://www.ncbi.nlm.nih.gov/pubmed/32888480 |
Human cortical sensorimotor network underlying feedback control of vocal pitch. | Chang EF, Niziolek CA, Knight RT, Nagarajan SS, Houde JF | Proceedings of the National Academy of Sciences of the United States of America | 23345447 | Proc Natl Acad Sci U S A | 2013 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/23345447 |
Speech synthesis from neural decoding of spoken sentences. | Anumanchipalli GK, Chartier J, Chang EF | Nature | 31019317 | Nature | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31019317 |
Functional organization of human sensorimotor cortex for speech articulation. | Bouchard KE, Mesgarani N, Johnson K, Chang EF | Nature | 23426266 | Nature | 2013 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/23426266 |
Syllabic (∼2-5 Hz) and fluctuation (∼1-10 Hz) ranges in speech and auditory processing. | Edwards E, Chang EF | Hearing research | 24035819 | Hear Res | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24035819 |
Transient aphasias after left hemisphere resective surgery. | Wilson SM, Lam D, Babiak MC, Perry DW, Shih T, Hess CP, Berger MS, Chang EF | Journal of neurosurgery | 26115463 | J Neurosurg | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26115463 |
Arresting a Torsin ATPase reshapes the endoplasmic reticulum. | Rose AE, Zhao C, Turner EM, Steyer AM, Schlieker C | The Journal of biological chemistry | 24275647 | J Biol Chem | 2014 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/24275647 |
Regulation of Torsin ATPases by LAP1 and LULL1. | Zhao C, Brown RS, Chase AR, Eisele MR, Schlieker C | Proceedings of the National Academy of Sciences of the United States of America | 23569223 | Proc Natl Acad Sci U S A | 2013 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/23569223 |
The mechanism of Torsin ATPase activation. | Brown RS, Zhao C, Chase AR, Wang J, Schlieker C | Proceedings of the National Academy of Sciences of the United States of America | 25352667 | Proc Natl Acad Sci U S A | 2014 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/25352667 |
Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum (ER) in Response to ER Stress and B Cell Stimulation. | Zhao C, Brown RS, Tang CH, Hu CC, Schlieker C | The Journal of biological chemistry | 26953341 | J Biol Chem | 2016 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/26953341 |
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The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations. | Tsai PL, Zhao C, Turner E, Schlieker C | eLife | 27336722 | Elife | 2016 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/27336722 |
The Torsin Activator LULL1 Is Required for Efficient Growth of Herpes Simplex Virus 1. | Turner EM, Brown RS, Laudermilch E, Tsai PL, Schlieker C | Journal of virology | 26041288 | J Virol | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26041288 |
Torsins: not your typical AAA+ ATPases. | Rose AE, Brown RS, Schlieker C | Critical reviews in biochemistry and molecular biology | 26592310 | Crit Rev Biochem Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26592310 |
Dissecting Torsin/cofactor function at the nuclear envelope: a genetic study. | Laudermilch E, Tsai PL, Graham M, Turner E, Zhao C, Schlieker C | Molecular biology of the cell | 27798237 | Mol Biol Cell | 2016 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/27798237 |
Alternative nuclear transport for cellular protein quality control. | Rose A, Schlieker C | Trends in cell biology | 22858153 | Trends Cell Biol | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22858153 |
Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle. | Little HC, Tan SY, Cali FM, Rodriguez S, Lei X, Wolfe A, Hug C, Wong GW | Molecular & cellular proteomics : MCP | 29735541 | Mol Cell Proteomics | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29735541 |
Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice. | Kasahara DI, Kim HY, Mathews JA, Verbout NG, Williams AS, Wurmbrand AP, Ninin FM, Neto FL, Benedito LA, Hug C, Umetsu DT, Shore SA | American journal of physiology. Lung cellular and molecular physiology | 24381131 | Am J Physiol Lung Cell Mol Physiol | 2014 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/24381131 |
Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. | Furuse Y, Finethy R, Saka HA, Xet-Mull AM, Sisk DM, Smith KL, Lee S, Coers J, Valdivia RH, Tobin DM, Cullen BR | PloS one | 25184567 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25184567 |
Interception of host angiogenic signalling limits mycobacterial growth. | Oehlers SH, Cronan MR, Scott NR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS, Tobin DM | Nature | 25470057 | Nature | 2015 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/25470057 |
Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases. | McClean CM, Tobin DM | Pathogens and disease | 27402783 | Pathog Dis | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27402783 |
Infection-Induced Vascular Permeability Aids Mycobacterial Growth. | Oehlers SH, Cronan MR, Beerman RW, Johnson MG, Huang J, Kontos CD, Stout JE, Tobin DM | The Journal of infectious diseases | 27496976 | J Infect Dis | 2017 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/27496976 |
The Macrophage-Specific Promoter mfap4 Allows Live, Long-Term Analysis of Macrophage Behavior during Mycobacterial Infection in Zebrafish. | Walton EM, Cronan MR, Beerman RW, Tobin DM | PloS one | 26445458 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26445458 |
CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections. | Cronan MR, Rosenberg AF, Oehlers SH, Saelens JW, Sisk DM, Jurcic Smith KL, Lee S, Tobin DM | Disease models & mechanisms | 26449262 | Dis Model Mech | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26449262 |
Epigenetic control of intestinal barrier function and inflammation in zebrafish. | Marjoram L, Alvers A, Deerhake ME, Bagwell J, Mankiewicz J, Cocchiaro JL, Beerman RW, Willer J, Sumigray KD, Katsanis N, Tobin DM, Rawls JF, Goll MG, Bagnat M | Proceedings of the National Academy of Sciences of the United States of America | 25730872 | Proc Natl Acad Sci U S A | 2015 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/25730872 |
TB: the Yin and Yang of lipid mediators. | Tobin DM, Ramakrishnan L | Current opinion in pharmacology | 23849093 | Curr Opin Pharmacol | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23849093 |
CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. | Wang L, Oehlers SH, Espenschied ST, Rawls JF, Tobin DM, Ko DC | Genome biology | 26374098 | Genome Biol | 2015 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/26374098 |
Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. | Cronan MR, Beerman RW, Rosenberg AF, Saelens JW, Johnson MG, Oehlers SH, Sisk DM, Jurcic Smith KL, Medvitz NA, Miller SE, Trinh LA, Fraser SE, Madden JF, Turner J, Stout JE, Lee S, Tobin DM | Immunity | 27760340 | Immunity | 2016 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/27760340 |
Host-Directed Therapies for Tuberculosis. | Tobin DM | Cold Spring Harbor perspectives in medicine | 25986592 | Cold Spring Harb Perspect Med | 2015 May 18 | https://www.ncbi.nlm.nih.gov/pubmed/25986592 |
Adventures within the speckled band: heterogeneity, angiogenesis, and balanced inflammation in the tuberculous granuloma. | Matty MA, Roca FJ, Cronan MR, Tobin DM | Immunological reviews | 25703566 | Immunol Rev | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25703566 |
Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion. | Tenor JL, Oehlers SH, Yang JL, Tobin DM, Perfect JR | mBio | 26419880 | mBio | 2015 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/26419880 |
Zebrafish: a see-through host and a fluorescent toolbox to probe host-pathogen interaction. | Tobin DM, May RC, Wheeler RT | PLoS pathogens | 22241986 | PLoS Pathog | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22241986 |
Live Imaging of Host-Pathogen Interactions in Zebrafish Larvae. | Matty MA, Oehlers SH, Tobin DM | Methods in molecular biology (Clifton, N.J.) | 27464810 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27464810 |
Drug-Inducible, Cell-Specific Manipulation of Intracellular Calcium in Zebrafish Through Mammalian TRPV1 Expression. | Matty MA, Beerman RW, Tobin DM | Zebrafish | 27058231 | Zebrafish | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27058231 |
An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection. | Tobin DM, Roca FJ, Ray JP, Ko DC, Ramakrishnan L | PloS one | 23874453 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23874453 |
Fit for consumption: zebrafish as a model for tuberculosis. | Cronan MR, Tobin DM | Disease models & mechanisms | 24973748 | Dis Model Mech | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24973748 |
Direct In Vivo Manipulation and Imaging of Calcium Transients in Neutrophils Identify a Critical Role for Leading-Edge Calcium Flux. | Beerman RW, Matty MA, Au GG, Looger LL, Choudhury KR, Keller PJ, Tobin DM | Cell reports | 26673320 | Cell Rep | 2015 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/26673320 |
Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration. | Berg RD, Levitte S, O'Sullivan MP, O'Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L | Cell | 27015311 | Cell | 2016 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/27015311 |
Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. | Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TT, Vary JC, Hawn TR, Dunstan SJ, Farrar JJ, Thwaites GE, King MC, Serhan CN, Ramakrishnan L | Cell | 22304914 | Cell | 2012 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/22304914 |
Thrombocyte Inhibition Restores Protective Immunity to Mycobacterial Infection in Zebrafish. | Hortle E, Johnson KE, Johansen MD, Nguyen T, Shavit JA, Britton WJ, Tobin DM, Oehlers SH | The Journal of infectious diseases | 30877311 | J Infect Dis | 2019 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/30877311 |
All signals lost. | Wilke KE, Carlson EE | Science translational medicine | 24048521 | Sci Transl Med | 2013 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/24048521 |
Mechanistic Studies of Bioorthogonal ATP Analogues for Assessment of Histidine Kinase Autophosphorylation. | Espinasse A, Wen X, Goodpaster JD, Carlson EE | ACS chemical biology | 32043868 | ACS Chem Biol | 2020 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/32043868 |
Disarming the virulence arsenal of Pseudomonas aeruginosa by blocking two-component system signaling. | Goswami M, Espinasse A, Carlson EE | Chemical science | 30542536 | Chem Sci | 2018 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/30542536 |
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases. | Goswami M, Wilke KE, Carlson EE | Journal of medicinal chemistry | 28933546 | J Med Chem | 2017 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/28933546 |
Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition. | Wilke KE, Fihn CA, Carlson EE | Bioorganic & medicinal chemistry | 29706527 | Bioorg Med Chem | 2018 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/29706527 |
Exploration of the Effects of γ-Phosphate-Modified ATP Analogues on Histidine Kinase Autophosphorylation. | Chase OM, Espinasse A, Wilke KE, Carlson EE | Biochemistry | 29944360 | Biochemistry | 2018 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/29944360 |
Profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39. | Kocaoglu O, Tsui HC, Winkler ME, Carlson EE | Antimicrobial agents and chemotherapy | 25845878 | Antimicrob Agents Chemother | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25845878 |
Chemoselective hydroxyl group transformation: an elusive target. | Trader DJ, Carlson EE | Molecular bioSystems | 22695722 | Mol Biosyst | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22695722 |
Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division. | Kocaoglu O, Calvo RA, Sham LT, Cozy LM, Lanning BR, Francis S, Winkler ME, Kearns DB, Carlson EE | ACS chemical biology | 22909777 | ACS Chem Biol | 2012 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/22909777 |
Thiol-ene enabled detection of thiophosphorylated kinase substrates. | Garber KC, Carlson EE | ACS chemical biology | 23668631 | ACS Chem Biol | 2013 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/23668631 |
Mechanistic insight into inhibition of two-component system signaling. | Francis S, Wilke KE, Brown DE, Carlson EE | MedChemComm | 23336064 | Medchemcomm | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23336064 |
2-Aminobenzothiazoles Inhibit Virulence Gene Expression and Block Polymyxin Resistance in Salmonella enterica. | Thielen MK, Vaneerd CK, Goswami M, Carlson EE, May JF | Chembiochem : a European journal of chemical biology | 32750193 | Chembiochem | 2020 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/32750193 |
Targeting multidrug resistant Staphylococcus infections with bacterial histidine kinase inhibitors. | Espinasse A, Goswami M, Yang J, Vorasin O, Ji Y, Carlson EE | Chemical science | 37206395 | Chem Sci | 2023 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/37206395 |
Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumoniae D39. | Tsui HT, Boersma MJ, Vella SA, Kocaoglu O, Kuru E, Peceny JK, Carlson EE, VanNieuwenhze MS, Brun YV, Shaw SL, Winkler ME | Molecular microbiology | 25099088 | Mol Microbiol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25099088 |
Progress and prospects for small-molecule probes of bacterial imaging. | Kocaoglu O, Carlson EE | Nature chemical biology | 27315537 | Nat Chem Biol | 2016 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/27315537 |
Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39. | Land AD, Tsui HC, Kocaoglu O, Vella SA, Shaw SL, Keen SK, Sham LT, Carlson EE, Winkler ME | Molecular microbiology | 24118410 | Mol Microbiol | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24118410 |
Penicillin-binding protein imaging probes. | Kocaoglu O, Carlson EE | Current protocols in chemical biology | 24391095 | Curr Protoc Chem Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24391095 |
Thiol-ene-Enabled Detection of Thiophosphorylation as a Labeling Strategy for Phosphoproteins. | Wilke KE, Carlson EE | Methods in molecular biology (Clifton, N.J.) | 26584915 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26584915 |
Profiling of β-lactam selectivity for penicillin-binding proteins in Escherichia coli strain DC2. | Kocaoglu O, Carlson EE | Antimicrobial agents and chemotherapy | 25733506 | Antimicrob Agents Chemother | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25733506 |
Activity-based probe for histidine kinase signaling. | Wilke KE, Francis S, Carlson EE | Journal of the American Chemical Society | 22606938 | J Am Chem Soc | 2012 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/22606938 |
Harnessing β-Lactam Antibiotics for Illumination of the Activity of Penicillin-Binding Proteins in Bacillus subtilis. | Sharifzadeh S, Dempwolff F, Kearns DB, Carlson EE | ACS chemical biology | 32155044 | ACS Chem Biol | 2020 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/32155044 |
Inactivation of multiple bacterial histidine kinases by targeting the ATP-binding domain. | Wilke KE, Francis S, Carlson EE | ACS chemical biology | 25531939 | ACS Chem Biol | 2015 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/25531939 |
Novel Electrophilic Scaffold for Imaging of Essential Penicillin-Binding Proteins in Streptococcus pneumoniae. | Sharifzadeh S, Boersma MJ, Kocaoglu O, Shokri A, Brown CL, Shirley JD, Winkler ME, Carlson EE | ACS chemical biology | 28990753 | ACS Chem Biol | 2017 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/28990753 |
Equilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics. | Pan L, Aller SG | Scientific reports | 25600711 | Sci Rep | 2015 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/25600711 |
In vitro evolution and affinity-maturation with Coliphage qβ display. | Skamel C, Aller SG, Bopda Waffo A | PloS one | 25393763 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25393763 |
Refined structures of mouse P-glycoprotein. | Li J, Jaimes KF, Aller SG | Protein science : a publication of the Protein Society | 24155053 | Protein Sci | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24155053 |
Tools and procedures for visualization of proteins and other biomolecules. | Pan L, Aller SG | Current protocols in molecular biology | 25827086 | Curr Protoc Mol Biol | 2015 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/25827086 |
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. | Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA | Nature methods | 26501517 | Nat Methods | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26501517 |
Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors. | Thakore PI, Gersbach CA | Methods in molecular biology (Clifton, N.J.) | 26443215 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26443215 |
A CRISPR/Cas9-based system for reprogramming cell lineage specification. | Chakraborty S, Ji H, Kabadi AM, Gersbach CA, Christoforou N, Leong KW | Stem cell reports | 25448066 | Stem Cell Reports | 2014 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/25448066 |
Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis. | Chakraborty S, Ji H, Chen J, Gersbach CA, Leong KW | Scientific reports | 25492703 | Sci Rep | 2014 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/25492703 |
Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain. | Kabadi AM, Thakore PI, Vockley CM, Ousterout DG, Gibson TM, Guilak F, Reddy TE, Gersbach CA | ACS synthetic biology | 25494287 | ACS Synth Biol | 2015 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/25494287 |
Increasing the specificity of CRISPR systems with engineered RNA secondary structures. | Kocak DD, Josephs EA, Bhandarkar V, Adkar SS, Kwon JB, Gersbach CA | Nature biotechnology | 30988504 | Nat Biotechnol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30988504 |
Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing. | Klann TS, Crawford GE, Reddy TE, Gersbach CA | Methods in molecular biology (Clifton, N.J.) | 29524151 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29524151 |
An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis. | Polstein LR, Juhas M, Hanna G, Bursac N, Gersbach CA | ACS synthetic biology | 28793186 | ACS Synth Biol | 2017 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/28793186 |
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells. | Pickar-Oliver A, Black JB, Lewis MM, Mutchnick KJ, Klann TS, Gilcrest KA, Sitton MJ, Nelson CE, Barrera A, Bartelt LC, Reddy TE, Beisel CL, Barrangou R, Gersbach CA | Nature biotechnology | 31548729 | Nat Biotechnol | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31548729 |
Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells. | Black JB, Adler AF, Wang HG, D'Ippolito AM, Hutchinson HA, Reddy TE, Pitt GS, Leong KW, Gersbach CA | Cell stem cell | 27524438 | Cell Stem Cell | 2016 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/27524438 |
Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine. | Gersbach CA, Perez-Pinera P | Expert opinion on therapeutic targets | 24917359 | Expert Opin Ther Targets | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24917359 |
Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. | Gersbach CA, Gaj T, Barbas CF 3rd | Accounts of chemical research | 24877793 | Acc Chem Res | 2014 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/24877793 |
Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens. | Black JB, McCutcheon SR, Dube S, Barrera A, Klann TS, Rice GA, Adkar SS, Soderling SH, Reddy TE, Gersbach CA | Cell reports | 33264623 | Cell Rep | 2020 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/33264623 |
Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. | Brunger JM, Huynh NP, Guenther CM, Perez-Pinera P, Moutos FT, Sanchez-Adams J, Gersbach CA, Guilak F | Proceedings of the National Academy of Sciences of the United States of America | 24550481 | Proc Natl Acad Sci U S A | 2014 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/24550481 |
Setting objective thresholds for rare event detection in flow cytometry. | Richards AJ, Staats J, Enzor J, McKinnon K, Frelinger J, Denny TN, Weinhold KJ, Chan C | Journal of immunological methods | 24727143 | J Immunol Methods | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24727143 |
Genome editing: the end of the beginning. | Doudna JA, Gersbach CA | Genome biology | 26700220 | Genome Biol | 2015 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/26700220 |
CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome. | Klann TS, Black JB, Chellappan M, Safi A, Song L, Hilton IB, Crawford GE, Reddy TE, Gersbach CA | Nature biotechnology | 28369033 | Nat Biotechnol | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28369033 |
Genome Engineering for Personalized Arthritis Therapeutics. | Adkar SS, Brunger JM, Willard VP, Wu CL, Gersbach CA, Guilak F | Trends in molecular medicine | 28887050 | Trends Mol Med | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28887050 |
Genome engineering: the next genomic revolution. | Gersbach CA | Nature methods | 25264777 | Nat Methods | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25264777 |
Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression. | Kabadi AM, Gersbach CA | Methods (San Diego, Calif.) | 25010559 | Methods | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25010559 |
Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector. | Kabadi AM, Ousterout DG, Hilton IB, Gersbach CA | Nucleic acids research | 25122746 | Nucleic Acids Res | 2014 Oct 29 | https://www.ncbi.nlm.nih.gov/pubmed/25122746 |
A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. | Polstein LR, Gersbach CA | Nature chemical biology | 25664691 | Nat Chem Biol | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25664691 |
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy. | Ousterout DG, Kabadi AM, Thakore PI, Majoros WH, Reddy TE, Gersbach CA | Nature communications | 25692716 | Nat Commun | 2015 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/25692716 |
The Development of TALE Nucleases for Biotechnology. | Ousterout DG, Gersbach CA | Methods in molecular biology (Clifton, N.J.) | 26443211 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26443211 |
Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases. | Ousterout DG, Kabadi AM, Thakore PI, Perez-Pinera P, Brown MT, Majoros WH, Reddy TE, Gersbach CA | Molecular therapy : the journal of the American Society of Gene Therapy | 25492562 | Mol Ther | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25492562 |
Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. | Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, Wu X, Zhu J, Boyington JC, Chen X, Shi W, Yang ZY, Doria-Rose NA, McKee K, O'Dell S, Schmidt SD, Chuang GY, Druz A, Soto C, Yang Y, Zhang B, Zhou T, Todd JP, Lloyd KE, Eudailey J, Roberts KE, Donald BR, Bailer RT, Ledgerwood J, NISC Comparative Sequencing Program, Mullikin JC, Shapiro L, Koup RA, Graham BS, Nason MC, Connors M, Haynes BF, Rao SS, Roederer M, Kwong PD, Mascola JR, Nabel GJ | Journal of virology | 25142607 | J Virol | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25142607 |
Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment. | Gibson TM, Gersbach CA | Integrative biology : quantitative biosciences from nano to macro | 25953198 | Integr Biol (Camb) | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25953198 |
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. | Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, Crawford GE, Reddy TE, Gersbach CA | Nature biotechnology | 25849900 | Nat Biotechnol | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25849900 |
Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage. | Josephs EA, Kocak DD, Fitzgibbon CJ, McMenemy J, Gersbach CA, Marszalek PE | Nucleic acids research | 26384421 | Nucleic Acids Res | 2015 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/26384421 |
Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors. | Polstein LR, Gersbach CA | Journal of the American Chemical Society | 22963237 | J Am Chem Soc | 2012 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/22963237 |
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. | Gaj T, Gersbach CA, Barbas CF 3rd | Trends in biotechnology | 23664777 | Trends Biotechnol | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23664777 |
Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy. | Nelson CE, Wu Y, Gemberling MP, Oliver ML, Waller MA, Bohning JD, Robinson-Hamm JN, Bulaklak K, Castellanos Rivera RM, Collier JH, Asokan A, Gersbach CA | Nature medicine | 30778238 | Nat Med | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30778238 |
RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. | Thakore PI, Kwon JB, Nelson CE, Rouse DC, Gemberling MP, Oliver ML, Gersbach CA | Nature communications | 29700298 | Nat Commun | 2018 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/29700298 |
Engineering Delivery Vehicles for Genome Editing. | Nelson CE, Gersbach CA | Annual review of chemical and biomolecular engineering | 27146557 | Annu Rev Chem Biomol Eng | 2016 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/27146557 |
Editing the epigenome: technologies for programmable transcription and epigenetic modulation. | Thakore PI, Black JB, Hilton IB, Gersbach CA | Nature methods | 26820547 | Nat Methods | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26820547 |
Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. | Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F | Stem cell reports | 28457885 | Stem Cell Reports | 2017 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/28457885 |
RNA-guided gene activation by CRISPR-Cas9-based transcription factors. | Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA | Nature methods | 23892895 | Nat Methods | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23892895 |
Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients. | Ousterout DG, Perez-Pinera P, Thakore PI, Kabadi AM, Brown MT, Qin X, Fedrigo O, Mouly V, Tremblay JP, Gersbach CA | Molecular therapy : the journal of the American Society of Gene Therapy | 23732986 | Mol Ther | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23732986 |
In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy. | Kwon JB, Ettyreddy AR, Vankara A, Bohning JD, Devlin G, Hauschka SD, Asokan A, Gersbach CA | Molecular therapy. Methods & clinical development | 33145368 | Mol Ther Methods Clin Dev | 2020 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/33145368 |
Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts. | Lee J, Xu L, Gibson TM, Gersbach CA, Sullenger BA | Biochemical and biophysical research communications | 27586271 | Biochem Biophys Res Commun | 2016 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/27586271 |
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. | Housden BE, Muhar M, Gemberling M, Gersbach CA, Stainier DY, Seydoux G, Mohr SE, Zuber J, Perrimon N | Nature reviews. Genetics | 27795562 | Nat Rev Genet | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27795562 |
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. | Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA | Science (New York, N.Y.) | 26721684 | Science | 2016 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/26721684 |
Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy. | Robinson-Hamm JN, Gersbach CA | Human genetics | 27542949 | Hum Genet | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27542949 |
CRISPR-based methods for high-throughput annotation of regulatory DNA. | Klann TS, Black JB, Gersbach CA | Current opinion in biotechnology | 29500989 | Curr Opin Biotechnol | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29500989 |
The role of single-cell analyses in understanding cell lineage commitment. | Gibson TM, Gersbach CA | Biotechnology journal | 23520130 | Biotechnol J | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23520130 |
Synergistic and tunable human gene activation by combinations of synthetic transcription factors. | Perez-Pinera P, Ousterout DG, Brunger JM, Farin AM, Glass KA, Guilak F, Crawford GE, Hartemink AJ, Gersbach CA | Nature methods | 23377379 | Nat Methods | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23377379 |
Advances in targeted genome editing. | Perez-Pinera P, Ousterout DG, Gersbach CA | Current opinion in chemical biology | 22819644 | Curr Opin Chem Biol | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22819644 |
Tissue-engineered cartilage with inducible and tunable immunomodulatory properties. | Glass KA, Link JM, Brunger JM, Moutos FT, Gersbach CA, Guilak F | Biomaterials | 24767790 | Biomaterials | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24767790 |
Light-inducible gene regulation with engineered zinc finger proteins. | Polstein LR, Gersbach CA | Methods in molecular biology (Clifton, N.J.) | 24718797 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24718797 |
Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases. | Perez-Pinera P, Ousterout DG, Brown MT, Gersbach CA | Nucleic acids research | 22169954 | Nucleic Acids Res | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22169954 |
CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues. | Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F | Arthritis & rheumatology (Hoboken, N.J.) | 27813286 | Arthritis Rheumatol | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/27813286 |
Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing. | Adkar SS, Wu CL, Willard VP, Dicks A, Ettyreddy A, Steward N, Bhutani N, Gersbach CA, Guilak F | Stem cells (Dayton, Ohio) | 30378731 | Stem Cells | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30378731 |
Enabling functional genomics with genome engineering. | Hilton IB, Gersbach CA | Genome research | 26430154 | Genome Res | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26430154 |
Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. | Diekman BO, Thakore PI, O'Connor SK, Willard VP, Brunger JM, Christoforou N, Leong KW, Gersbach CA, Guilak F | Tissue engineering. Part A | 25517798 | Tissue Eng Part A | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25517798 |
Genome-editing Technologies for Gene and Cell Therapy. | Maeder ML, Gersbach CA | Molecular therapy : the journal of the American Society of Gene Therapy | 26755333 | Mol Ther | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26755333 |
Transferable model for chromosome architecture. | Di Pierro M, Zhang B, Aiden EL, Wolynes PG, Onuchic JN | Proceedings of the National Academy of Sciences of the United States of America | 27688758 | Proc Natl Acad Sci U S A | 2016 Oct 25 | https://www.ncbi.nlm.nih.gov/pubmed/27688758 |
De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds. | Dudchenko O, Batra SS, Omer AD, Nyquist SK, Hoeger M, Durand NC, Shamim MS, Machol I, Lander ES, Aiden AP, Aiden EL | Science (New York, N.Y.) | 28336562 | Science | 2017 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/28336562 |
A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. | El Khattabi L, Zhao H, Kalchschmidt J, Young N, Jung S, Van Blerkom P, Kieffer-Kwon P, Kieffer-Kwon KR, Park S, Wang X, Krebs J, Tripathi S, Sakabe N, Sobreira DR, Huang SC, Rao SSP, Pruett N, Chauss D, Sadler E, Lopez A, Nóbrega MA, Aiden EL, Asturias FJ, Casellas R | Cell | 31402173 | Cell | 2019 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/31402173 |
Nuclear biology: what's been most surprising? | Dekker J, Wysocka J, Mattaj I, Lieberman Aiden E, Pikaard C | Cell | 23616995 | Cell | 2013 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/23616995 |
Cohesin Loss Eliminates All Loop Domains. | Rao SSP, Huang SC, Glenn St Hilaire B, Engreitz JM, Perez EM, Kieffer-Kwon KR, Sanborn AL, Johnstone SE, Bascom GD, Bochkov ID, Huang X, Shamim MS, Shin J, Turner D, Ye Z, Omer AD, Robinson JT, Schlick T, Bernstein BE, Casellas R, Lander ES, Aiden EL | Cell | 28985562 | Cell | 2017 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/28985562 |
Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development. | Phanstiel DH, Van Bortle K, Spacek D, Hess GT, Shamim MS, Machol I, Love MI, Aiden EL, Bassik MC, Snyder MP | Molecular cell | 28890333 | Mol Cell | 2017 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/28890333 |
Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom. | Durand NC, Robinson JT, Shamim MS, Machol I, Mesirov JP, Lander ES, Aiden EL | Cell systems | 27467250 | Cell Syst | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27467250 |
Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function. | Lawlor N, Márquez EJ, Orchard P, Narisu N, Shamim MS, Thibodeau A, Varshney A, Kursawe R, Erdos MR, Kanke M, Gu H, Pak E, Dutra A, Russell S, Li X, Piecuch E, Luo O, Chines PS, Fuchbserger C, NIH Intramural Sequencing Center, Sethupathy P, Aiden AP, Ruan Y, Aiden EL, Collins FS, Ucar D, Parker SCJ, Stitzel ML | Cell reports | 30650367 | Cell Rep | 2019 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/30650367 |
Juicebox.js Provides a Cloud-Based Visualization System for Hi-C Data. | Robinson JT, Turner D, Durand NC, Thorvaldsdóttir H, Mesirov JP, Aiden EL | Cell systems | 29428417 | Cell Syst | 2018 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/29428417 |
Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments. | Durand NC, Shamim MS, Machol I, Rao SS, Huntley MH, Lander ES, Aiden EL | Cell systems | 27467249 | Cell Syst | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27467249 |
The Energetics and Physiological Impact of Cohesin Extrusion. | Vian L, Pękowska A, Rao SSP, Kieffer-Kwon KR, Jung S, Baranello L, Huang SC, El Khattabi L, Dose M, Pruett N, Sanborn AL, Canela A, Maman Y, Oksanen A, Resch W, Li X, Lee B, Kovalchuk AL, Tang Z, Nelson S, Di Pierro M, Cheng RR, Machol I, St Hilaire BG, Durand NC, Shamim MS, Stamenova EK, Onuchic JN, Ruan Y, Nussenzweig A, Levens D, Aiden EL, Casellas R | Cell | 29706548 | Cell | 2018 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/29706548 |
The expanding scope of DNA sequencing. | Shendure J, Lieberman Aiden E | Nature biotechnology | 23138308 | Nat Biotechnol | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23138308 |
Improved reference genome of Aedes aegypti informs arbovirus vector control. | Matthews BJ, Dudchenko O, Kingan SB, Koren S, Antoshechkin I, Crawford JE, Glassford WJ, Herre M, Redmond SN, Rose NH, Weedall GD, Wu Y, Batra SS, Brito-Sierra CA, Buckingham SD, Campbell CL, Chan S, Cox E, Evans BR, Fansiri T, Filipović I, Fontaine A, Gloria-Soria A, Hall R, Joardar VS, Jones AK, Kay RGG, Kodali VK, Lee J, Lycett GJ, Mitchell SN, Muehling J, Murphy MR, Omer AD, Partridge FA, Peluso P, Aiden AP, Ramasamy V, Rašić G, Roy S, Saavedra-Rodriguez K, Sharan S, Sharma A, Smith ML, Turner J, Weakley AM, Zhao Z, Akbari OS, Black WC 4th, Cao H, Darby AC, Hill CA, Johnston JS, Murphy TD, Raikhel AS, Sattelle DB, Sharakhov IV, White BJ, Zhao L, Aiden EL, Mann RS, Lambrechts L, Powell JR, Sharakhova MV, Tu Z, Robertson HM, McBride CS, Hastie AR, Korlach J, Neafsey DE, Phillippy AM, Vosshall LB | Nature | 30429615 | Nature | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30429615 |
High-resolution antibody dynamics of vaccine-induced immune responses. | Laserson U, Vigneault F, Gadala-Maria D, Yaari G, Uduman M, Vander Heiden JA, Kelton W, Taek Jung S, Liu Y, Laserson J, Chari R, Lee JH, Bachelet I, Hickey B, Lieberman-Aiden E, Hanczaruk B, Simen BB, Egholm M, Koller D, Georgiou G, Kleinstein SH, Church GM | Proceedings of the National Academy of Sciences of the United States of America | 24639495 | Proc Natl Acad Sci U S A | 2014 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24639495 |
Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity. | Zhang X, Jeong M, Huang X, Wang XQ, Wang X, Zhou W, Shamim MS, Gore H, Himadewi P, Liu Y, Bochkov ID, Reyes J, Doty M, Huang YH, Jung H, Heikamp E, Aiden AP, Li W, Su J, Aiden EL, Goodell MA | Molecular cell | 32386543 | Mol Cell | 2020 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/32386543 |
A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. | Rao SS, Huntley MH, Durand NC, Stamenova EK, Bochkov ID, Robinson JT, Sanborn AL, Machol I, Omer AD, Lander ES, Aiden EL | Cell | 25497547 | Cell | 2014 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/25497547 |
GE Prize essay. Zoom! | Lieberman Aiden E | Science (New York, N.Y.) | 22144611 | Science | 2011 Dec 2 | https://www.ncbi.nlm.nih.gov/pubmed/22144611 |
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes. | Sanborn AL, Rao SS, Huang SC, Durand NC, Huntley MH, Jewett AI, Bochkov ID, Chinnappan D, Cutkosky A, Li J, Geeting KP, Gnirke A, Melnikov A, McKenna D, Stamenova EK, Lander ES, Aiden EL | Proceedings of the National Academy of Sciences of the United States of America | 26499245 | Proc Natl Acad Sci U S A | 2015 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/26499245 |
Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling. | Nir G, Farabella I, Pérez Estrada C, Ebeling CG, Beliveau BJ, Sasaki HM, Lee SD, Nguyen SC, McCole RB, Chattoraj S, Erceg J, AlHaj Abed J, Martins NMC, Nguyen HQ, Hannan MA, Russell S, Durand NC, Rao SSP, Kishi JY, Soler-Vila P, Di Pierro M, Onuchic JN, Callahan SP, Schreiner JM, Stuckey JA, Yin P, Aiden EL, Marti-Renom MA, Wu CT | PLoS genetics | 30586358 | PLoS Genet | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30586358 |
De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture. | Di Pierro M, Cheng RR, Lieberman Aiden E, Wolynes PG, Onuchic JN | Proceedings of the National Academy of Sciences of the United States of America | 29087948 | Proc Natl Acad Sci U S A | 2017 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/29087948 |
Polycomb-mediated chromatin loops revealed by a subkilobase-resolution chromatin interaction map. | Eagen KP, Aiden EL, Kornberg RD | Proceedings of the National Academy of Sciences of the United States of America | 28765367 | Proc Natl Acad Sci U S A | 2017 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/28765367 |
Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture. | Darrow EM, Huntley MH, Dudchenko O, Stamenova EK, Durand NC, Sun Z, Huang SC, Sanborn AL, Machol I, Shamim M, Seberg AP, Lander ES, Chadwick BP, Aiden EL | Proceedings of the National Academy of Sciences of the United States of America | 27432957 | Proc Natl Acad Sci U S A | 2016 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/27432957 |
Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation. | Kieffer-Kwon KR, Nimura K, Rao SSP, Xu J, Jung S, Pekowska A, Dose M, Stevens E, Mathe E, Dong P, Huang SC, Ricci MA, Baranello L, Zheng Y, Tomassoni Ardori F, Resch W, Stavreva D, Nelson S, McAndrew M, Casellas A, Finn E, Gregory C, St Hilaire BG, Johnson SM, Dubois W, Cosma MP, Batchelor E, Levens D, Phair RD, Misteli T, Tessarollo L, Hager G, Lakadamyali M, Liu Z, Floer M, Shroff H, Aiden EL, Casellas R | Molecular cell | 28803781 | Mol Cell | 2017 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/28803781 |
An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening. | MacConnell AB, Price AK, Paegel BM | ACS combinatorial science | 28199790 | ACS Comb Sci | 2017 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/28199790 |
hνSABR: Photochemical Dose-Response Bead Screening in Droplets. | Price AK, MacConnell AB, Paegel BM | Analytical chemistry | 26815064 | Anal Chem | 2016 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26815064 |
Evolution of a mass spectrometry-grade protease with PTM-directed specificity. | Tran DT, Cavett VJ, Dang VQ, Torres HL, Paegel BM | Proceedings of the National Academy of Sciences of the United States of America | 27940920 | Proc Natl Acad Sci U S A | 2016 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/27940920 |
DNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library Synthesis. | MacConnell AB, McEnaney PJ, Cavett VJ, Paegel BM | ACS combinatorial science | 26290177 | ACS Comb Sci | 2015 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/26290177 |
Microfluidic bead suspension hopper. | Price AK, MacConnell AB, Paegel BM | Analytical chemistry | 24761972 | Anal Chem | 2014 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/24761972 |
Chemoselective Coupling Preserves the Substrate Integrity of Surface-Immobilized Oligonucleotides for Emulsion PCR-Based Gene Library Construction. | Malone ML, Cavett VJ, Paegel BM | ACS combinatorial science | 28064476 | ACS Comb Sci | 2017 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/28064476 |
High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections. | Mendes KR, Malone ML, Ndungu JM, Suponitsky-Kroyter I, Cavett VJ, McEnaney PJ, MacConnell AB, Doran TM, Ronacher K, Stanley K, Utset O, Walzl G, Paegel BM, Kodadek T | ACS chemical biology | 27957856 | ACS Chem Biol | 2017 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/27957856 |
Discovery in Droplets. | Price AK, Paegel BM | Analytical chemistry | 26558892 | Anal Chem | 2016 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/26558892 |
What is a "DNA-Compatible" Reaction? | Malone ML, Paegel BM | ACS combinatorial science | 26971959 | ACS Comb Sci | 2016 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/26971959 |
Small-Molecule Patterning via Prefunctionalized Alkanethiols. | Cao HH, Nakatsuka N, Deshayes S, Abendroth JM, Yang H, Weiss PS, Kasko AM, Andrews AM | Chemistry of materials : a publication of the American Chemical Society | 30828130 | Chem Mater | 2018 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/30828130 |
Steric effects in peptide and protein exchange with activated disulfides. | Kerr J, Schlosser JL, Griffin DR, Wong DY, Kasko AM | Biomacromolecules | 23865598 | Biomacromolecules | 2013 Aug 12 | https://www.ncbi.nlm.nih.gov/pubmed/23865598 |
Engineering persister-specific antibiotics with synergistic antimicrobial functions. | Schmidt NW, Deshayes S, Hawker S, Blacker A, Kasko AM, Wong GC | ACS nano | 25130648 | ACS Nano | 2014 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/25130648 |
Pentobra: A Potent Antibiotic with Multiple Layers of Selective Antimicrobial Mechanisms against Propionibacterium Acnes. | Schmidt NW, Agak GW, Deshayes S, Yu Y, Blacker A, Champer J, Xian W, Kasko AM, Kim J, Wong GCL | The Journal of investigative dermatology | 25668237 | J Invest Dermatol | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25668237 |
Complex dynamic substrate control: dual-tone hydrogel photoresists allow double-dissociation of topography and modulus. | Xue C, Wong DY, Kasko AM | Advanced materials (Deerfield Beach, Fla.) | 24339260 | Adv Mater | 2014 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/24339260 |
Photodegradable macromers and hydrogels for live cell encapsulation and release. | Griffin DR, Kasko AM | Journal of the American Chemical Society | 22765384 | J Am Chem Soc | 2012 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/22765384 |
Photo-selective delivery of model therapeutics from hydrogels. | Griffin DR, Kasko AM | ACS macro letters | 25285242 | ACS Macro Lett | 2012 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/25285242 |
Low-Dose, Long-Wave UV Light Does Not Affect Gene Expression of Human Mesenchymal Stem Cells. | Wong DY, Ranganath T, Kasko AM | PloS one | 26418040 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26418040 |
Synthesis of photodegradable macromers for conjugation and release of bioactive molecules. | Griffin DR, Schlosser JL, Lam SF, Nguyen TH, Maynard HD, Kasko AM | Biomacromolecules | 23506440 | Biomacromolecules | 2013 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/23506440 |
Shape-Changing Photodegradable Hydrogels for Dynamic 3D Cell Culture. | Käpylä E, Delgado SM, Kasko AM | ACS applied materials & interfaces | 27322508 | ACS Appl Mater Interfaces | 2016 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/27322508 |
Aptamer Recognition of Multiplexed Small-Molecule-Functionalized Substrates. | Nakatsuka N, Cao HH, Deshayes S, Melkonian AL, Kasko AM, Weiss PS, Andrews AM | ACS applied materials & interfaces | 29851335 | ACS Appl Mater Interfaces | 2018 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/29851335 |
Magnetic field activated drug delivery using thermodegradable azo-functionalised PEG-coated core-shell mesoporous silica nanoparticles. | Saint-Cricq P, Deshayes S, Zink JI, Kasko AM | Nanoscale | 26181577 | Nanoscale | 2015 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/26181577 |
Single-cell systems biology by super-resolution imaging and combinatorial labeling. | Lubeck E, Cai L | Nature methods | 22660740 | Nat Methods | 2012 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/22660740 |
Turning single cells into microarrays by super-resolution barcoding. | Cai L | Briefings in functional genomics | 23178478 | Brief Funct Genomics | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23178478 |
In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus. | Shah S, Lubeck E, Zhou W, Cai L | Neuron | 27764670 | Neuron | 2016 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/27764670 |
Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing. | Shah S, Lubeck E, Schwarzkopf M, He TF, Greenbaum A, Sohn CH, Lignell A, Choi HM, Gradinaru V, Pierce NA, Cai L | Development (Cambridge, England) | 27342713 | Development | 2016 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/27342713 |
Identification of a neural crest stem cell niche by Spatial Genomic Analysis. | Lignell A, Kerosuo L, Streichan SJ, Cai L, Bronner ME | Nature communications | 29184067 | Nat Commun | 2017 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/29184067 |
Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA. | Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, Hughes C, Fonseca-Pereira D, Veiga-Fernandes H, Raj A, Kambayashi T, Brodsky IE, O'Shea JJ, Wherry EJ, Goff LA, Rinn JL, Williams A, Flavell RA, Henao-Mejia J | Immunity | 28930659 | Immunity | 2017 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/28930659 |
Intercellular mRNA trafficking via membrane nanotube-like extensions in mammalian cells. | Haimovich G, Ecker CM, Dunagin MC, Eggan E, Raj A, Gerst JE, Singer RH | Proceedings of the National Academy of Sciences of the United States of America | 29078295 | Proc Natl Acad Sci U S A | 2017 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/29078295 |
Half dozen of one, six billion of the other: What can small- and large-scale molecular systems biology learn from one another? | Mellis IA, Raj A | Genome research | 26430156 | Genome Res | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26430156 |
Visualizing allele-specific expression in single cells reveals epigenetic mosaicism in an H19 loss-of-imprinting mutant. | Ginart P, Kalish JM, Jiang CL, Yu AC, Bartolomei MS, Raj A | Genes & development | 26944681 | Genes Dev | 2016 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26944681 |
What's Luck Got to Do with It: Single Cells, Multiple Fates, and Biological Nondeterminism. | Symmons O, Raj A | Molecular cell | 27259209 | Mol Cell | 2016 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/27259209 |
A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition. | Hsiung CC, Bartman CR, Huang P, Ginart P, Stonestrom AJ, Keller CA, Face C, Jahn KS, Evans P, Sankaranarayanan L, Giardine B, Hardison RC, Raj A, Blobel GA | Genes & development | 27340175 | Genes Dev | 2016 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/27340175 |
Using variability in gene expression as a tool for studying gene regulation. | Padovan-Merhar O, Raj A | Wiley interdisciplinary reviews. Systems biology and medicine | 23996796 | Wiley Interdiscip Rev Syst Biol Med | 2013 Nov-Dec | https://www.ncbi.nlm.nih.gov/pubmed/23996796 |
Targeting tumor vasculature: expanding the potential of DNA cancer vaccines. | Ugel S, Facciponte JG, De Sanctis F, Facciabene A | Cancer immunology, immunotherapy : CII | 26267042 | Cancer Immunol Immunother | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26267042 |
Amendments: Author Correction: ClampFISH detects individual nucleic acid molecules using click chemistry-based amplification. | Rouhanifard SH, Mellis IA, Dunagin M, Bayatpour S, Jiang CL, Dardani I, Symmons O, Emert B, Torre E, Cote A, Sullivan A, Stamatoyannopoulos JA, Raj A | Nature biotechnology | 30605160 | Nat Biotechnol | 2019 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/30605160 |
Spo0A~P imposes a temporal gate for the bimodal expression of competence in Bacillus subtilis. | Mirouze N, Desai Y, Raj A, Dubnau D | PLoS genetics | 22412392 | PLoS Genet | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22412392 |
The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. | Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA | Molecular cell | 28388437 | Mol Cell | 2017 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/28388437 |
Visualizing adenosine-to-inosine RNA editing in single mammalian cells. | Mellis IA, Gupte R, Raj A, Rouhanifard SH | Nature methods | 28604724 | Nat Methods | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28604724 |
Gene transcription is coordinated with, but not dependent on, cell divisions during C. elegans embryonic fate specification. | Nair G, Walton T, Murray JI, Raj A | Development (Cambridge, England) | 23863485 | Development | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23863485 |
Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation. | Levesque MJ, Raj A | Nature methods | 23416756 | Nat Methods | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23416756 |
Tumor endothelial marker 1-specific DNA vaccination targets tumor vasculature. | Facciponte JG, Ugel S, De Sanctis F, Li C, Wang L, Nair G, Sehgal S, Raj A, Matthaiou E, Coukos G, Facciabene A | The Journal of clinical investigation | 24642465 | J Clin Invest | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24642465 |
Visualization of lncRNA by single-molecule fluorescence in situ hybridization. | Dunagin M, Cabili MN, Rinn J, Raj A | Methods in molecular biology (Clifton, N.J.) | 25555572 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25555572 |
Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting. | Symmons O, Chang M, Mellis IA, Kalish JM, Park J, Suszták K, Bartolomei MS, Raj A | PLoS genetics | 30625149 | PLoS Genet | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30625149 |
Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms. | Padovan-Merhar O, Nair GP, Biaesch AG, Mayer A, Scarfone S, Foley SW, Wu AR, Churchman LS, Singh A, Raj A | Molecular cell | 25866248 | Mol Cell | 2015 Apr 16 | https://www.ncbi.nlm.nih.gov/pubmed/25866248 |
Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping. | Bartman CR, Hsu SC, Hsiung CC, Raj A, Blobel GA | Molecular cell | 27067601 | Mol Cell | 2016 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/27067601 |
Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency. | Abranches E, Guedes AM, Moravec M, Maamar H, Svoboda P, Raj A, Henrique D | Development (Cambridge, England) | 25005472 | Development | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25005472 |
The Bicoid class homeodomain factors ceh-36/OTX and unc-30/PITX cooperate in C. elegans embryonic progenitor cells to regulate robust development. | Walton T, Preston E, Nair G, Zacharias AL, Raj A, Murray JI | PLoS genetics | 25738873 | PLoS Genet | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25738873 |
Dynamic enhancer-gene body contacts during transcription elongation. | Lee K, Hsiung CC, Huang P, Raj A, Blobel GA | Genes & development | 26443845 | Genes Dev | 2015 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/26443845 |
LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint. | Dimitrova N, Zamudio JR, Jong RM, Soukup D, Resnick R, Sarma K, Ward AJ, Raj A, Lee JT, Sharp PA, Jacks T | Molecular cell | 24857549 | Mol Cell | 2014 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/24857549 |
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance. | Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M, Eggan E, Anastopoulos IN, Vargas-Garcia CA, Singh A, Nathanson KL, Herlyn M, Raj A | Nature | 28607484 | Nature | 2017 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/28607484 |
Quantitative assessment of ratiometric bimolecular beacons as a tool for imaging single engineered RNA transcripts and measuring gene expression in living cells. | Zhang X, Song Y, Shah AY, Lekova V, Raj A, Huang L, Behlke MA, Tsourkas A | Nucleic acids research | 23814183 | Nucleic Acids Res | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23814183 |
Turbo FISH: a method for rapid single molecule RNA FISH. | Shaffer SM, Wu MT, Levesque MJ, Raj A | PloS one | 24066168 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24066168 |
linc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cis. | Maamar H, Cabili MN, Rinn J, Raj A | Genes & development | 23723417 | Genes Dev | 2013 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/23723417 |
The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. | Kotzin JJ, Spencer SP, McCright SJ, Kumar DBU, Collet MA, Mowel WK, Elliott EN, Uyar A, Makiya MA, Dunagin MC, Harman CCD, Virtue AT, Zhu S, Bailis W, Stein J, Hughes C, Raj A, Wherry EJ, Goff LA, Klion AD, Rinn JL, Williams A, Flavell RA, Henao-Mejia J | Nature | 27525555 | Nature | 2016 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/27525555 |
SAVER: gene expression recovery for single-cell RNA sequencing. | Huang M, Wang J, Torre E, Dueck H, Shaffer S, Bonasio R, Murray JI, Raj A, Li M, Zhang NR | Nature methods | 29941873 | Nat Methods | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29941873 |
Nanoscale imaging of RNA with expansion microscopy. | Chen F, Wassie AT, Cote AJ, Sinha A, Alon S, Asano S, Daugharthy ER, Chang JB, Marblestone A, Church GM, Raj A, Boyden ES | Nature methods | 27376770 | Nat Methods | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27376770 |
Visualizing SNVs to quantify allele-specific expression in single cells. | Levesque MJ, Ginart P, Wei Y, Raj A | Nature methods | 23913259 | Nat Methods | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23913259 |
Control of somatic tissue differentiation by the long non-coding RNA TINCR. | Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, Aiyer S, Raj A, Rinn JL, Chang HY, Khavari PA | Nature | 23201690 | Nature | 2013 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/23201690 |
Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a. | Weis B, Schmidt J, Maamar H, Raj A, Lin H, Tóth C, Riedmann K, Raddatz G, Seitz HK, Ho AD, Lyko F, Linhart HG | Oncogene | 24837369 | Oncogene | 2015 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/24837369 |
Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila. | Panda D, Pascual-Garcia P, Dunagin M, Tudor M, Hopkins KC, Xu J, Gold B, Raj A, Capelson M, Cherry S | Proceedings of the National Academy of Sciences of the United States of America | 25197089 | Proc Natl Acad Sci U S A | 2014 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/25197089 |
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. | Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov AV, Anderson SM, Dunagin M, Pimkin M, Gore M, Sun D, Konuthula N, Raj A, An X, Mohandas N, Bodine DM, Hardison RC, Weiss MJ | Blood | 24497530 | Blood | 2014 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/24497530 |
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. | Hacisuleyman E, Goff LA, Trapnell C, Williams A, Henao-Mejia J, Sun L, McClanahan P, Hendrickson DG, Sauvageau M, Kelley DR, Morse M, Engreitz J, Lander ES, Guttman M, Lodish HF, Flavell R, Raj A, Rinn JL | Nature structural & molecular biology | 24463464 | Nat Struct Mol Biol | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24463464 |
Single-cell differences in matrix gene expression do not predict matrix deposition. | Cote AJ, McLeod CM, Farrell MJ, McClanahan PD, Dunagin MC, Raj A, Mauck RL | Nature communications | 26936319 | Nat Commun | 2016 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/26936319 |
Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH. | Torre E, Dueck H, Shaffer S, Gospocic J, Gupte R, Bonasio R, Kim J, Murray J, Raj A | Cell systems | 29454938 | Cell Syst | 2018 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/29454938 |
Transcriptional Bursting Explains the Noise-Versus-Mean Relationship in mRNA and Protein Levels. | Dar RD, Shaffer SM, Singh A, Razooky BS, Simpson ML, Raj A, Weinberger LS | PloS one | 27467384 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27467384 |
Heterogeneous lineage marker expression in naive embryonic stem cells is mostly due to spontaneous differentiation. | Nair G, Abranches E, Guedes AM, Henrique D, Raj A | Scientific reports | 26292941 | Sci Rep | 2015 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/26292941 |
Multiplexed detection of viral infections using rapid in situ RNA analysis on a chip. | Shaffer SM, Joshi RP, Chambers BS, Sterken D, Biaesch AG, Gabrieli DJ, Li Y, Feemster KA, Hensley SE, Issadore D, Raj A | Lab on a chip | 26113495 | Lab Chip | 2015 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/26113495 |
Robust hematopoietic progenitor cell commitment in the presence of a conflicting cue. | Shah NA, Levesque MJ, Raj A, Sarkar CA | Journal of cell science | 26159733 | J Cell Sci | 2015 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/26159733 |
Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution. | Cabili MN, Dunagin MC, McClanahan PD, Biaesch A, Padovan-Merhar O, Regev A, Rinn JL, Raj A | Genome biology | 25630241 | Genome Biol | 2015 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/25630241 |
Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I. | Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, López CB | mBio | 26443454 | mBio | 2015 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/26443454 |
Translating the genome in time and space: specialized ribosomes, RNA regulons, and RNA-binding proteins. | Shi Z, Barna M | Annual review of cell and developmental biology | 26443190 | Annu Rev Cell Dev Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26443190 |
RNA regulons in Hox 5' UTRs confer ribosome specificity to gene regulation. | Xue S, Tian S, Fujii K, Kladwang W, Das R, Barna M | Nature | 25409156 | Nature | 2015 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/25409156 |
Differential Requirements for eIF4E Dose in Normal Development and Cancer. | Truitt ML, Conn CS, Shi Z, Pang X, Tokuyasu T, Coady AM, Seo Y, Barna M, Ruggero D | Cell | 26095252 | Cell | 2015 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/26095252 |
Ribosomes take control. | Barna M | Proceedings of the National Academy of Sciences of the United States of America | 23243144 | Proc Natl Acad Sci U S A | 2013 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/23243144 |
Cis-regulatory RNA elements that regulate specialized ribosome activity. | Xue S, Barna M | RNA biology | 26327194 | RNA Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26327194 |
Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide. | Shi Z, Fujii K, Kovary KM, Genuth NR, Röst HL, Teruel MN, Barna M | Molecular cell | 28625553 | Mol Cell | 2017 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/28625553 |
Specialized ribosomes: a new frontier in gene regulation and organismal biology. | Xue S, Barna M | Nature reviews. Molecular cell biology | 22617470 | Nat Rev Mol Cell Biol | 2012 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/22617470 |
Tailor made protein synthesis for HSCs. | Barna M, Ruggero D | Cell stem cell | 24702992 | Cell Stem Cell | 2014 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/24702992 |
The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. | Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M | Cell | 28575669 | Cell | 2017 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/28575669 |
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. | Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Ishijima J, Shiroishi T, Barna M | Cell | 21529712 | Cell | 2011 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/21529712 |
Force Feedback Controls Motor Activity and Mechanical Properties of Self-Assembling Branched Actin Networks. | Bieling P, Li TD, Weichsel J, McGorty R, Jreij P, Huang B, Fletcher DA, Mullins RD | Cell | 26771487 | Cell | 2016 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/26771487 |
Single cell optical imaging and spectroscopy. | Stender AS, Marchuk K, Liu C, Sander S, Meyer MW, Smith EA, Neupane B, Wang G, Li J, Cheng JX, Huang B, Fang N | Chemical reviews | 23410134 | Chem Rev | 2013 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/23410134 |
Versatile protein tagging in cells with split fluorescent protein. | Kamiyama D, Sekine S, Barsi-Rhyne B, Hu J, Chen B, Gilbert LA, Ishikawa H, Leonetti MD, Marshall WF, Weissman JS, Huang B | Nature communications | 26988139 | Nat Commun | 2016 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/26988139 |
Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization. | Mennella V, Keszthelyi B, McDonald KL, Chhun B, Kan F, Rogers GC, Huang B, Agard DA | Nature cell biology | 23086239 | Nat Cell Biol | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23086239 |
2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas. | Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM | Cancer research | 29358170 | Cancer Res | 2018 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/29358170 |
Correction of depth-dependent aberrations in 3D single-molecule localization and super-resolution microscopy. | McGorty R, Schnitzbauer J, Zhang W, Huang B | Optics letters | 24562125 | Opt Lett | 2014 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/24562125 |
Active Microscope Stabilization in Three Dimensions Using Image Correlation. | McGorty R, Kamiyama D, Huang B | Optical nanoscopy | 24380058 | Opt Nanoscopy | 2013 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/24380058 |
Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory. | Puchner EM, Walter JM, Kasper R, Huang B, Lim WA | Proceedings of the National Academy of Sciences of the United States of America | 24043832 | Proc Natl Acad Sci U S A | 2013 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/24043832 |
Localization events-based sample drift correction for localization microscopy with redundant cross-correlation algorithm. | Wang Y, Schnitzbauer J, Hu Z, Li X, Cheng Y, Huang ZL, Huang B | Optics express | 24977854 | Opt Express | 2014 Jun 30 | https://www.ncbi.nlm.nih.gov/pubmed/24977854 |
Deformed alignment of super-resolution images for semi-flexible structures. | Shi X, Garcia G 3rd, Wang Y, Reiter JF, Huang B | PloS one | 30865666 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30865666 |
Improved split fluorescent proteins for endogenous protein labeling. | Feng S, Sekine S, Pessino V, Li H, Leonetti MD, Huang B | Nature communications | 28851864 | Nat Commun | 2017 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/28851864 |
Covalent Protein Labeling by SpyTag-SpyCatcher in Fixed Cells for Super-Resolution Microscopy. | Pessino V, Citron YR, Feng S, Huang B | Chembiochem : a European journal of chemical biology | 28514494 | Chembiochem | 2017 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/28514494 |
Amorphous no more: subdiffraction view of the pericentriolar material architecture. | Mennella V, Agard DA, Huang B, Pelletier L | Trends in cell biology | 24268653 | Trends Cell Biol | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24268653 |
A scalable strategy for high-throughput GFP tagging of endogenous human proteins. | Leonetti MD, Sekine S, Kamiyama D, Weissman JS, Huang B | Proceedings of the National Academy of Sciences of the United States of America | 27274053 | Proc Natl Acad Sci U S A | 2016 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/27274053 |
Imaging Specific Genomic DNA in Living Cells. | Chen B, Guan J, Huang B | Annual review of biophysics | 27145877 | Annu Rev Biophys | 2016 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/27145877 |
Live Cell Imaging of Endogenous mRNA Using RNA-Based Fluorescence "Turn-On" Probe. | Ong WQ, Citron YR, Sekine S, Huang B | ACS chemical biology | 28103687 | ACS Chem Biol | 2017 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/28103687 |
Correlation analysis framework for localization-based superresolution microscopy. | Schnitzbauer J, Wang Y, Zhao S, Bakalar M, Nuwal T, Chen B, Huang B | Proceedings of the National Academy of Sciences of the United States of America | 29531072 | Proc Natl Acad Sci U S A | 2018 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/29531072 |
Development in the STORM. | Kamiyama D, Huang B | Developmental cell | 23237944 | Dev Cell | 2012 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/23237944 |
Faster STORM using compressed sensing. | Zhu L, Zhang W, Elnatan D, Huang B | Nature methods | 22522657 | Nat Methods | 2012 Apr 22 | https://www.ncbi.nlm.nih.gov/pubmed/22522657 |
4Pi fluorescence detection and 3D particle localization with a single objective. | Schnitzbauer J, McGorty R, Huang B | Optics express | 24105517 | Opt Express | 2013 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/24105517 |
SnapShot: Light microscopy. | Kasper R, Huang B | Cell | 22118471 | Cell | 2011 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/22118471 |
The centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles. | Citron YR, Fagerstrom CJ, Keszthelyi B, Huang B, Rusan NM, Kelly MJS, Agard DA | PloS one | 29315319 | PLoS One | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29315319 |
Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome. | Shi X, Garcia G 3rd, Van De Weghe JC, McGorty R, Pazour GJ, Doherty D, Huang B, Reiter JF | Nature cell biology | 28846093 | Nat Cell Biol | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28846093 |
EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms. | van Lengerich B, Agnew C, Puchner EM, Huang B, Jura N | Proceedings of the National Academy of Sciences of the United States of America | 28320942 | Proc Natl Acad Sci U S A | 2017 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/28320942 |
Heavy water: a simple solution to increasing the brightness of fluorescent proteins in super-resolution imaging. | Ong WQ, Citron YR, Schnitzbauer J, Kamiyama D, Huang B | Chemical communications (Cambridge, England) | 26226621 | Chem Commun (Camb) | 2015 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/26226621 |
Label-retention expansion microscopy. | Shi X, Li Q, Dai Z, Tran AA, Feng S, Ramirez AD, Lin Z, Wang X, Chow TT, Chen J, Kumar D, McColloch AR, Reiter JF, Huang EJ, Seiple IB, Huang B | The Journal of cell biology | 34228783 | J Cell Biol | 2021 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/34228783 |
Cross-hierarchy systems principles. | Goentoro L | Current opinion in systems biology | 28983520 | Curr Opin Syst Biol | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/28983520 |
Signaling pathways as linear transmitters. | Nunns H, Goentoro L | eLife | 30222104 | Elife | 2018 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/30222104 |
The functional role of astrocyte calcium signaling in cortical blood flow regulation. | Biesecker KR, Srienc AI | The Journal of neuroscience : the official journal of the Society for Neuroscience | 25609605 | J Neurosci | 2015 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/25609605 |
Sensing relative signal in the Tgf-β/Smad pathway. | Frick CL, Yarka C, Nunns H, Goentoro L | Proceedings of the National Academy of Sciences of the United States of America | 28320972 | Proc Natl Acad Sci U S A | 2017 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/28320972 |
Two-Element Transcriptional Regulation in the Canonical Wnt Pathway. | Kim K, Cho J, Hilzinger TS, Nunns H, Liu A, Ryba BE, Goentoro L | Current biology : CB | 28756947 | Curr Biol | 2017 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/28756947 |
The tbx2a/b transcription factors direct pronephros segmentation and corpuscle of Stannius formation in zebrafish. | Drummond BE, Li Y, Marra AN, Cheng CN, Wingert RA | Developmental biology | 27840199 | Dev Biol | 2017 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/27840199 |
Evolving technology: creating kidney organoids from stem cells. | Chambers JM, McKee RA, Drummond BE, Wingert RA | AIMS bioengineering | 28393110 | AIMS Bioeng | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/28393110 |
Roles of Iroquois Transcription Factors in Kidney Development. | Marra AN, Wingert RA | Cell & developmental biology | 24855634 | Cell Dev Biol | 2014 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/24855634 |
Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta. | Gerlach GF, Wingert RA | Developmental biology | 25446529 | Dev Biol | 2014 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/25446529 |
Molecular Mechanisms of Podocyte Development Revealed by Zebrafish Kidney Research. | Miceli R, Kroeger P, Wingert R | Cell & developmental biology | 25485314 | Cell Dev Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25485314 |
Renal stem cell reprogramming: Prospects in regenerative medicine. | Morales EE, Wingert RA | World journal of stem cells | 25258667 | World J Stem Cells | 2014 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/25258667 |
Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish. | Cheng CN, Wingert RA | Developmental biology | 25542995 | Dev Biol | 2015 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/25542995 |
Analysis of nephron composition and function in the adult zebrafish kidney. | McCampbell KK, Springer KN, Wingert RA | Journal of visualized experiments : JoVE | 25145398 | J Vis Exp | 2014 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/25145398 |
Regenerative medicine for the kidney: stem cell prospects & challenges. | Li Y, Wingert RA | Clinical and translational medicine | 23688352 | Clin Transl Med | 2013 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/23688352 |
Insights into kidney stem cell development and regeneration using zebrafish. | Drummond BE, Wingert RA | World journal of stem cells | 26981168 | World J Stem Cells | 2016 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/26981168 |
Zebrafish nephrogenesis is regulated by interactions between retinoic acid, mecom, and Notch signaling. | Li Y, Cheng CN, Verdun VA, Wingert RA | Developmental biology | 24309209 | Dev Biol | 2014 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/24309209 |
Zebrafish Renal Pathology: Emerging Models of Acute Kidney Injury. | McKee RA, Wingert RA | Current pathobiology reports | 25973344 | Curr Pathobiol Rep | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25973344 |
Production of haploid zebrafish embryos by in vitro fertilization. | Kroeger PT Jr, Poureetezadi SJ, McKee R, Jou J, Miceli R, Wingert RA | Journal of visualized experiments : JoVE | 25046024 | J Vis Exp | 2014 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/25046024 |
Microbead Implantation in the Zebrafish Embryo. | Gerlach GF, Morales EE, Wingert RA | Journal of visualized experiments : JoVE | 26274386 | J Vis Exp | 2015 Jul 30 | https://www.ncbi.nlm.nih.gov/pubmed/26274386 |
Atlas of Cellular Dynamics during Zebrafish Adult Kidney Regeneration. | McCampbell KK, Springer KN, Wingert RA | Stem cells international | 26089919 | Stem Cells Int | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26089919 |
Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury. | McKee RA, Wingert RA | Journal of visualized experiments : JoVE | 27500823 | J Vis Exp | 2016 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/27500823 |
Kidney organogenesis in the zebrafish: insights into vertebrate nephrogenesis and regeneration. | Gerlach GF, Wingert RA | Wiley interdisciplinary reviews. Developmental biology | 24014448 | Wiley Interdiscip Rev Dev Biol | 2013 Sep-Oct | https://www.ncbi.nlm.nih.gov/pubmed/24014448 |
Temporal and spatial expression of tight junction genes during zebrafish pronephros development. | McKee R, Gerlach GF, Jou J, Cheng CN, Wingert RA | Gene expression patterns : GEP | 25460834 | Gene Expr Patterns | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25460834 |
Using zebrafish to study podocyte genesis during kidney development and regeneration. | Kroeger PT Jr, Wingert RA | Genesis (New York, N.Y. : 2000) | 24920186 | Genesis | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/24920186 |
Renal stem cells: fact or science fiction? | McCampbell KK, Wingert RA | The Biochemical journal | 22574774 | Biochem J | 2012 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/22574774 |
Little fish, big catch: zebrafish as a model for kidney disease. | Poureetezadi SJ, Wingert RA | Kidney international | 27165832 | Kidney Int | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27165832 |
Flat mount preparation for observation and analysis of zebrafish embryo specimens stained by whole mount in situ hybridization. | Cheng CN, Li Y, Marra AN, Verdun V, Wingert RA | Journal of visualized experiments : JoVE | 25078510 | J Vis Exp | 2014 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/25078510 |
Congenital and Acute Kidney Disease: Translational Research Insights from Zebrafish Chemical Genetics. | Poureetezadi SJ, Wingert RA | General medicine (Los Angeles, Calif.) | 24653992 | Gen Med (Los Angel) | 2013 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/24653992 |
Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development. | Marra AN, Wingert RA | Developmental biology | 26827902 | Dev Biol | 2016 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/26827902 |
Renal progenitors: Roles in kidney disease and regeneration. | Chambers BE, Wingert RA | World journal of stem cells | 27928463 | World J Stem Cells | 2016 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/27928463 |
Repopulating Decellularized Kidney Scaffolds: An Avenue for Ex Vivo Organ Generation. | McKee RA, Wingert RA | Materials (Basel, Switzerland) | 27375844 | Materials (Basel) | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/27375844 |
New tides: using zebrafish to study renal regeneration. | McCampbell KK, Wingert RA | Translational research : the journal of laboratory and clinical medicine | 24183931 | Transl Res | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24183931 |
A manual small molecule screen approaching high-throughput using zebrafish embryos. | Poureetezadi SJ, Donahue EK, Wingert RA | Journal of visualized experiments : JoVE | 25407322 | J Vis Exp | 2014 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/25407322 |
Early transcriptional and epigenetic regulation of CD8(+) T cell differentiation revealed by single-cell RNA sequencing. | Kakaradov B, Arsenio J, Widjaja CE, He Z, Aigner S, Metz PJ, Yu B, Wehrens EJ, Lopez J, Kim SH, Zuniga EI, Goldrath AW, Chang JT, Yeo GW | Nature immunology | 28218746 | Nat Immunol | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/28218746 |
Geometrically controlled asymmetric division of CD4+ T cells studied by immunological synapse arrays. | Jung HR, Song KH, Chang JT, Doh J | PloS one | 24632942 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24632942 |
Cutting edge: Asymmetric memory T cell division in response to rechallenge. | Ciocca ML, Barnett BE, Burkhardt JK, Chang JT, Reiner SL | Journal of immunology (Baltimore, Md. : 1950) | 22467651 | J Immunol | 2012 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/22467651 |
Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance. | Klann JE, Kim SH, Remedios KA, He Z, Metz PJ, Lopez J, Tysl T, Olvera JG, Ablack JN, Cantor JM, Boland BS, Yeo G, Zheng Y, Lu LF, Bui JD, Ginsberg MH, Petrich BG, Chang JT | Journal of immunology (Baltimore, Md. : 1950) | 29703862 | J Immunol | 2018 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/29703862 |
Molecular regulation of effector and memory T cell differentiation. | Chang JT, Wherry EJ, Goldrath AW | Nature immunology | 25396352 | Nat Immunol | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25396352 |
Reply to: "CD8(+) T cell diversification by asymmetric cell division". | Arsenio J, Kakaradov B, Metz PJ, Yeo GW, Chang JT | Nature immunology | 26287585 | Nat Immunol | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26287585 |
Regulation of asymmetric division and CD8+ T lymphocyte fate specification by protein kinase Cζ and protein kinase Cλ/ι. | Metz PJ, Arsenio J, Kakaradov B, Kim SH, Remedios KA, Oakley K, Akimoto K, Ohno S, Yeo GW, Chang JT | Journal of immunology (Baltimore, Md. : 1950) | 25617472 | J Immunol | 2015 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/25617472 |
A gp130-Src-YAP module links inflammation to epithelial regeneration. | Taniguchi K, Wu LW, Grivennikov SI, de Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS, Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, Zucman-Rossi J, Guan KL, Karin M | Nature | 25731159 | Nature | 2015 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/25731159 |
Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide. | Corriden R, Hollands A, Olson J, Derieux J, Lopez J, Chang JT, Gonzalez DJ, Nizet V | Nature communications | 26458291 | Nat Commun | 2015 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/26458291 |
Ubiquitylation of CD98 limits cell proliferation and clonal expansion. | Ablack JN, Metz PJ, Chang JT, Cantor JM, Ginsberg MH | Journal of cell science | 26493331 | J Cell Sci | 2015 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/26493331 |
Validation of gene expression biomarker analysis for biopsy-based clinical trials in Crohn's disease. | Boland BS, Boyle DL, Sandborn WJ, Firestein GS, Levesque BG, Hillman J, Zhang B, Proudfoot J, Eckmann L, Ernst PB, Rivera-Nieves J, Pola S, Copur-Dahi N, Zou G, Chang JT | Inflammatory bowel diseases | 25545378 | Inflamm Bowel Dis | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25545378 |
Update on Janus kinase antagonists in inflammatory bowel disease. | Boland BS, Sandborn WJ, Chang JT | Gastroenterology clinics of North America | 25110261 | Gastroenterol Clin North Am | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25110261 |
Polarity and lymphocyte fate determination. | Chang JT | Current opinion in cell biology | 22658837 | Curr Opin Cell Biol | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22658837 |
Asymmetric Cell Division in T Lymphocyte Fate Diversification. | Arsenio J, Metz PJ, Chang JT | Trends in immunology | 26474675 | Trends Immunol | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26474675 |
The Microtubule-Associated Protein Lis1 Regulates T Lymphocyte Homeostasis and Differentiation. | Ngoi SM, Lopez JM, Chang JT | Journal of immunology (Baltimore, Md. : 1950) | 27029586 | J Immunol | 2016 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/27029586 |
Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification. | Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, Leestemaker Y, Berkers CR, de Jong A, Florea BI, Fisch K, Lopez J, Kim SH, Garcia DA, Searles S, Bui JD, Chang AN, Yates JR 3rd, Goldrath AW, Overkleeft HS, Ovaa H, Chang JT | The Journal of clinical investigation | 28846070 | J Clin Invest | 2017 Oct 2 | https://www.ncbi.nlm.nih.gov/pubmed/28846070 |
Talin Plays a Critical Role in the Maintenance of the Regulatory T Cell Pool. | Klann JE, Remedios KA, Kim SH, Metz PJ, Lopez J, Mack LA, Zheng Y, Ginsberg MH, Petrich BG, Chang JT | Journal of immunology (Baltimore, Md. : 1950) | 28515282 | J Immunol | 2017 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/28515282 |
Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates. | Metz PJ, Lopez J, Kim SH, Akimoto K, Ohno S, Chang JT | Scientific reports | 26765121 | Sci Rep | 2016 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/26765121 |
Early specification of CD8+ T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses. | Arsenio J, Kakaradov B, Metz PJ, Kim SH, Yeo GW, Chang JT | Nature immunology | 24584088 | Nat Immunol | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24584088 |
Validated gene expression biomarker analysis for biopsy-based clinical trials in ulcerative colitis. | Boland BS, Boyle DL, Sandborn WJ, Firestein GS, Levesque BG, Hillman J, Zhang B, Proudfoot J, Eckmann L, Ernst PB, Rivera-Nieves J, Pola S, Copur-Dahi N, Chang JT | Alimentary pharmacology & therapeutics | 25041724 | Aliment Pharmacol Ther | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25041724 |
Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition. | Banno A, Garcia DA, van Baarsel ED, Metz PJ, Fisch K, Widjaja CE, Kim SH, Lopez J, Chang AN, Geurink PP, Florea BI, Overkleeft HS, Ovaa H, Bui JD, Yang J, Chang JT | Oncotarget | 26930717 | Oncotarget | 2016 Apr 19 | https://www.ncbi.nlm.nih.gov/pubmed/26930717 |
USP11 Enhances TGFβ-Induced Epithelial-Mesenchymal Plasticity and Human Breast Cancer Metastasis. | Garcia DA, Baek C, Estrada MV, Tysl T, Bennett EJ, Yang J, Chang JT | Molecular cancer research : MCR | 29724812 | Mol Cancer Res | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29724812 |
Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency. | Boland BS, Widjaja CE, Banno A, Zhang B, Kim SH, Stoven S, Peterson MR, Jones MC, Su HI, Crowe SE, Bui JD, Ho SB, Okugawa Y, Goel A, Marietta EV, Khosroheidari M, Jepsen K, Aramburu J, López-Rodríguez C, Sandborn WJ, Murray JA, Harismendy O, Chang JT | Journal of immunology (Baltimore, Md. : 1950) | 25667416 | J Immunol | 2015 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/25667416 |
Virulence Factor Targeting of the Bacterial Pathogen Staphylococcus aureus for Vaccine and Therapeutics. | Kane TL, Carothers KE, Lee SW | Current drug targets | 27894236 | Curr Drug Targets | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/27894236 |
Using bacterial genomes and essential genes for the development of new antibiotics. | Fields FR, Lee SW, McConnell MJ | Biochemical pharmacology | 27940263 | Biochem Pharmacol | 2017 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/27940263 |
Knowing is half the battle: targeting virulence factors of group A Streptococcus for vaccine and therapeutics. | Thomas CL, Lee SW | Current drug targets | 22206254 | Curr Drug Targets | 2012 Mar | https://www.ncbi.nlm.nih.gov/pubmed/22206254 |
A large scale prediction of bacteriocin gene blocks suggests a wide functional spectrum for bacteriocins. | Morton JT, Freed SD, Lee SW, Friedberg I | BMC bioinformatics | 26558535 | BMC Bioinformatics | 2015 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/26558535 |
Design and evaluation of a peptide-based immunotoxin for breast cancer therapeutics. | Weigel KJ, Shen L, Thomas CL, Alber D, Drapalik L, Schafer ZT, Lee SW | FEBS open bio | 25853036 | FEBS Open Bio | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25853036 |
CovRS-Regulated Transcriptome Analysis of a Hypervirulent M23 Strain of Group A Streptococcus pyogenes Provides New Insights into Virulence Determinants. | Bao YJ, Liang Z, Mayfield JA, Lee SW, Ploplis VA, Castellino FJ | Journal of bacteriology | 26216843 | J Bacteriol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26216843 |
Rationally Designed Minimal Bioactive Domains of AS-48 Bacteriocin Homologs Possess Potent Antileishmanial Properties. | Corman HN, Ross JN, Fields FR, Shoue DA, McDowell MA, Lee SW | Microbiology spectrum | 36342284 | Microbiol Spectr | 2022 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/36342284 |
Rational design of syn-safencin, a novel linear antimicrobial peptide derived from the circular bacteriocin safencin AS-48. | Fields FR, Carothers KE, Balsara RD, Ploplis VA, Castellino FJ, Lee SW | The Journal of antibiotics | 29463889 | J Antibiot (Tokyo) | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29463889 |
Synthesis, biological evaluation, and in silico study of novel library sulfonates containing quinazolin-4(3H)-one derivatives as potential aldose reductase inhibitors. | Tokalı FS, Demir Y, Demircioğlu İH, Türkeş C, Kalay E, Şendil K, Beydemir Ş | Drug development research | 34585414 | Drug Dev Res | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/34585414 |
HIV protease inhibitors block streptolysin S production. | Maxson T, Deane CD, Molloy EM, Cox CL, Markley AL, Lee SW, Mitchell DA | ACS chemical biology | 25668590 | ACS Chem Biol | 2015 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/25668590 |
Neutralization of Streptolysin S-Dependent and Independent Inflammatory Cytokine IL-1β Activity Reduces Pathology During Early Group A Streptococcal Skin Infection. | Flaherty RA, Donahue DL, Carothers KE, Ross JN, Ploplis VA, Castellino FJ, Lee SW | Frontiers in cellular and infection microbiology | 30018884 | Front Cell Infect Microbiol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30018884 |
Synthetic Peptide Libraries Designed From a Minimal Alpha-Helical Domain of AS-48-Bacteriocin Homologs Exhibit Potent Antibacterial Activity. | Ross JN, Fields FR, Kalwajtys VR, Gonzalez AJ, O'Connor S, Zhang A, Moran TE, Hammers DE, Carothers KE, Lee SW | Frontiers in microbiology | 33281785 | Front Microbiol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33281785 |
The wide world of ribosomally encoded bacterial peptides. | Flaherty RA, Freed SD, Lee SW | PLoS pathogens | 25079075 | PLoS Pathog | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25079075 |
Implementation of a Permeable Membrane Insert-based Infection System to Study the Effects of Secreted Bacterial Toxins on Mammalian Host Cells. | Flaherty RA, Lee SW | Journal of visualized experiments : JoVE | 27585035 | J Vis Exp | 2016 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/27585035 |
A multiparametric computational algorithm for comprehensive assessment of genetic mutations in mucopolysaccharidosis type IIIA (Sanfilippo syndrome). | Ugrinov KG, Freed SD, Thomas CL, Lee SW | PloS one | 25807448 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25807448 |
Streptolysin S Promotes Programmed Cell Death and Enhances Inflammatory Signaling in Epithelial Keratinocytes during Group A Streptococcus Infection. | Flaherty RA, Puricelli JM, Higashi DL, Park CJ, Lee SW | Infection and immunity | 26238711 | Infect Immun | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26238711 |
Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains. | Fields FR, Freed SD, Carothers KE, Hamid MN, Hammers DE, Ross JN, Kalwajtys VR, Gonzalez AJ, Hildreth AD, Friedberg I, Lee SW | Drug development research | 31483516 | Drug Dev Res | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31483516 |
Group A Streptococcus-Induced Activation of Human Plasminogen Is Required for Keratinocyte Wound Retraction and Rapid Clot Dissolution. | Vu HM, Hammers DE, Liang Z, Nguyen GL, Benz ME, Moran TE, Higashi DL, Park CJ, Ayinuola YA, Donahue DL, Flores-Mireles AL, Ploplis VA, Castellino FJ, Lee SW | Frontiers in cardiovascular medicine | 34179133 | Front Cardiovasc Med | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34179133 |
Comparative effects of teriparatide, denosumab, and combination therapy on peripheral compartmental bone density, microarchitecture, and estimated strength: the DATA-HRpQCT Study. | Tsai JN, Uihlein AV, Burnett-Bowie SA, Neer RM, Zhu Y, Derrico N, Lee H, Bouxsein ML, Leder BZ | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 25043459 | J Bone Miner Res | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25043459 |
Interactions between B lymphocytes and the osteoblast lineage in bone marrow. | Panaroni C, Wu JY | Calcified tissue international | 23839529 | Calcif Tissue Int | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23839529 |
Differential regulation of myeloid leukemias by the bone marrow microenvironment. | Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT | Nature medicine | 24162813 | Nat Med | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24162813 |
Pluripotent Stem Cells and Skeletal Regeneration--Promise and Potential. | Wu JY | Current osteoporosis reports | 26260198 | Curr Osteoporos Rep | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26260198 |
Pluripotent stem cells as a source of osteoblasts for bone tissue regeneration. | Zhu H, Kimura T, Swami S, Wu JY | Biomaterials | 29456164 | Biomaterials | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29456164 |
In Vivo Rescue of the Hematopoietic Niche By Pluripotent Stem Cell Complementation of Defective Osteoblast Compartments. | Chubb R, Oh J, Riley AK, Kimura T, Wu SM, Wu JY | Stem cells (Dayton, Ohio) | 28741855 | Stem Cells | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28741855 |
Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling. | Fulzele K, Krause DS, Panaroni C, Saini V, Barry KJ, Liu X, Lotinun S, Baron R, Bonewald L, Feng JQ, Chen M, Weinstein LS, Wu JY, Kronenberg HM, Scadden DT, Divieti Pajevic P | Blood | 23160461 | Blood | 2013 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/23160461 |
Direct Reprogramming of Mouse Fibroblasts into Functional Osteoblasts. | Zhu H, Swami S, Yang P, Shapiro F, Wu JY | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 31793059 | J Bone Miner Res | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31793059 |
Mesenchymal lineage cells and their importance in B lymphocyte niches. | Green AC, Rudolph-Stringer V, Chantry AD, Wu JY, Purton LE | Bone | 29183783 | Bone | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29183783 |
Teriparatide (PTH 1-34) treatment increases peripheral hematopoietic stem cells in postmenopausal women. | Yu EW, Kumbhani R, Siwila-Sackman E, DeLelys M, Preffer FI, Leder BZ, Wu JY | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 24420643 | J Bone Miner Res | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24420643 |
Bone Density Loss Is Associated With Blood Cell Counts. | Valderrábano RJ, Lui LY, Lee J, Cummings SR, Orwoll ES, Hoffman AR, Wu JY, Osteoporotic Fractures in Men (MrOS) Study Research Group | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 27653240 | J Bone Miner Res | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/27653240 |
Mesenchymal progenitors and the osteoblast lineage in bone marrow hematopoietic niches. | Panaroni C, Tzeng YS, Saeed H, Wu JY | Current osteoporosis reports | 24477415 | Curr Osteoporos Rep | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24477415 |
Bone and blood interactions in human health and disease. | Valderrábano RJ, Wu JY | Bone | 29476979 | Bone | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29476979 |
Prevention of breast cancer skeletal metastases with parathyroid hormone. | Swami S, Johnson J, Bettinson LA, Kimura T, Zhu H, Albertelli MA, Johnson RW, Wu JY | JCI insight | 28878134 | JCI Insight | 2017 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/28878134 |
Older Men With Anemia Have Increased Fracture Risk Independent of Bone Mineral Density. | Valderrábano RJ, Lee J, Lui LY, Hoffman AR, Cummings SR, Orwoll ES, Wu JY, Osteoporotic Fractures in Men (MrOS) Study Research Group | The Journal of clinical endocrinology and metabolism | 28368469 | J Clin Endocrinol Metab | 2017 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/28368469 |
Induction of Osteoblasts by Direct Reprogramming of Mouse Fibroblasts. | Zhu H, Wu JY | Methods in molecular biology (Clifton, N.J.) | 32474879 | Methods Mol Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32474879 |
PTH Signaling in Osteoprogenitors Is Essential for B-Lymphocyte Differentiation and Mobilization. | Panaroni C, Fulzele K, Saini V, Chubb R, Pajevic PD, Wu JY | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 26191777 | J Bone Miner Res | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26191777 |
Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates. | Melby JO, Nard NJ, Mitchell DA | Current opinion in chemical biology | 21429787 | Curr Opin Chem Biol | 2011 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21429787 |
Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis. | Lee J, Hao Y, Blair PM, Melby JO, Agarwal V, Burkhart BJ, Nair SK, Mitchell DA | Proceedings of the National Academy of Sciences of the United States of America | 23878226 | Proc Natl Acad Sci U S A | 2013 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/23878226 |
A new genome-mining tool redefines the lasso peptide biosynthetic landscape. | Tietz JI, Schwalen CJ, Patel PS, Maxson T, Blair PM, Tai HC, Zakai UI, Mitchell DA | Nature chemical biology | 28244986 | Nat Chem Biol | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28244986 |
Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete. | Metelev M, Tietz JI, Melby JO, Blair PM, Zhu L, Livnat I, Severinov K, Mitchell DA | Chemistry & biology | 25601074 | Chem Biol | 2015 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/25601074 |
YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations. | Dunbar KL, Melby JO, Mitchell DA | Nature chemical biology | 22522320 | Nat Chem Biol | 2012 Apr 22 | https://www.ncbi.nlm.nih.gov/pubmed/22522320 |
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. | Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian KD, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJ, Rebuffat S, Ross RP, Sahl HG, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Süssmuth RD, Tagg JR, Tang GL, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA | Natural product reports | 23165928 | Nat Prod Rep | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23165928 |
Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products. | Molloy EM, Tietz JI, Blair PM, Mitchell DA | Bioorganic & medicinal chemistry | 27234886 | Bioorg Med Chem | 2016 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/27234886 |
In Vitro Biosynthesis and Substrate Tolerance of the Plantazolicin Family of Natural Products. | Deane CD, Burkhart BJ, Saint-Vincent PMB, Tietz JI, Lin A, Mitchell DA | ACS chemical biology | 27248686 | ACS Chem Biol | 2016 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/27248686 |
Lessons learned from the transformation of natural product discovery to a genome-driven endeavor. | Deane CD, Mitchell DA | Journal of industrial microbiology & biotechnology | 24142337 | J Ind Microbiol Biotechnol | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24142337 |
YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function. | Burkhart BJ, Schwalen CJ, Mann G, Naismith JH, Mitchell DA | Chemical reviews | 28256131 | Chem Rev | 2017 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/28256131 |
Streptolysin S-like virulence factors: the continuing sagA. | Molloy EM, Cotter PD, Hill C, Mitchell DA, Ross RP | Nature reviews. Microbiology | 21822292 | Nat Rev Microbiol | 2011 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/21822292 |
Identification of the minimal cytolytic unit for streptolysin S and an expansion of the toxin family. | Molloy EM, Casjens SR, Cox CL, Maxson T, Ethridge NA, Margos G, Fingerle V, Mitchell DA | BMC microbiology | 26204951 | BMC Microbiol | 2015 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/26204951 |
Targeting Reactive Carbonyls for Identifying Natural Products and Their Biosynthetic Origins. | Maxson T, Tietz JI, Hudson GA, Guo XR, Tai HC, Mitchell DA | Journal of the American Chemical Society | 27797509 | J Am Chem Soc | 2016 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/27797509 |
HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis. | Zhang Y, Fu-Yang Lin, Li K, Zhu W, Liu YL, Cao R, Pang R, Lee E, Axelson J, Hensler M, Wang K, Molohon KJ, Wang Y, Mitchell DA, Nizet V, Oldfield E | ACS medicinal chemistry letters | 22662288 | ACS Med Chem Lett | 2012 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/22662288 |
Engineering unnatural variants of plantazolicin through codon reprogramming. | Deane CD, Melby JO, Molohon KJ, Susarrey AR, Mitchell DA | ACS chemical biology | 23823732 | ACS Chem Biol | 2013 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/23823732 |
Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. | Hao Y, Saint-Vincent PMB, Sharma A, Mitchell DA, Nair SK | ACS chemical biology | 25635336 | ACS Chem Biol | 2015 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/25635336 |
Undecaprenyl diphosphate synthase inhibitors: antibacterial drug leads. | Sinko W, Wang Y, Zhu W, Zhang Y, Feixas F, Cox CL, Mitchell DA, Oldfield E, McCammon JA | Journal of medicinal chemistry | 24827744 | J Med Chem | 2014 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/24827744 |
Nucleophilic 1,4-additions for natural product discovery. | Cox CL, Tietz JI, Sokolowski K, Melby JO, Doroghazi JR, Mitchell DA | ACS chemical biology | 24937678 | ACS Chem Biol | 2014 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/24937678 |
Selectivity, directionality, and promiscuity in peptide processing from a Bacillus sp. Al Hakam cyclodehydratase. | Melby JO, Dunbar KL, Trinh NQ, Mitchell DA | Journal of the American Chemical Society | 22401305 | J Am Chem Soc | 2012 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/22401305 |
Multitarget drug discovery for tuberculosis and other infectious diseases. | Li K, Schurig-Briccio LA, Feng X, Upadhyay A, Pujari V, Lechartier B, Fontes FL, Yang H, Rao G, Zhu W, Gulati A, No JH, Cintra G, Bogue S, Liu YL, Molohon K, Orlean P, Mitchell DA, Freitas-Junior L, Ren F, Sun H, Jiang T, Li Y, Guo RT, Cole ST, Gennis RB, Crick DC, Oldfield E | Journal of medicinal chemistry | 24568559 | J Med Chem | 2014 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/24568559 |
Head-to-Head Prenyl Synthases in Pathogenic Bacteria. | Schwalen CJ, Feng X, Liu W, O-Dowd B, Ko TP, Shin CJ, Guo RT, Mitchell DA, Oldfield E | Chembiochem : a European journal of chemical biology | 28340291 | Chembiochem | 2017 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/28340291 |
Synthesis of plantazolicin analogues enables dissection of ligand binding interactions of a highly selective methyltransferase. | Sharma A, Saint-Vincent PMB, Mitchell DA | Organic letters | 24063702 | Org Lett | 2013 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/24063702 |
Targeted Treatment for Bacterial Infections: Prospects for Pathogen-Specific Antibiotics Coupled with Rapid Diagnostics. | Maxson T, Mitchell DA | Tetrahedron | 27429480 | Tetrahedron | 2016 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/27429480 |
Crystal structure and absolute configuration of (3S,4aS,8aS)-N-tert-butyl-2-[(S)-3-(2-chloro-4-nitro-benzamido)-2-hy-droxy-prop-yl]deca-hydro-isoquinoline-3-carboxamide and (3S,4aS,8aS)-N-tert-butyl-2-{(S)-2-[(S)-1-(2-chloro-4-nitro-benzoyl)pyrrolidin-2-yl]-2-hy-droxy-eth-yl}deca-hydro-iso-quinoline-3-carboxamide. | Maxson T, Bertke JA, Gray DL, Mitchell DA | Acta crystallographica. Section E, Crystallographic communications | 26594520 | Acta Crystallogr E Crystallogr Commun | 2015 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/26594520 |
The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles. | Cox CL, Doroghazi JR, Mitchell DA | BMC genomics | 26462797 | BMC Genomics | 2015 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/26462797 |
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin. | Hudson GA, Zhang Z, Tietz JI, Mitchell DA, van der Donk WA | Journal of the American Chemical Society | 26675417 | J Am Chem Soc | 2015 Dec 30 | https://www.ncbi.nlm.nih.gov/pubmed/26675417 |
Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis. | Njire M, Wang N, Wang B, Tan Y, Cai X, Liu Y, Mugweru J, Guo J, Hameed HMA, Tan S, Liu J, Yew WW, Nuermberger E, Lamichhane G, Liu J, Zhang T | Antimicrobial agents and chemotherapy | 28438933 | Antimicrob Agents Chemother | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28438933 |
Carbapenems against Mycobacterium tuberculosis: a review of the evidence. | Jaganath D, Lamichhane G, Shah M | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | 27776583 | Int J Tuberc Lung Dis | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27776583 |
Non-classical transpeptidases yield insight into new antibacterials. | Kumar P, Kaushik A, Lloyd EP, Li SG, Mattoo R, Ammerman NC, Bell DT, Perryman AL, Zandi TA, Ekins S, Ginell SL, Townsend CA, Freundlich JS, Lamichhane G | Nature chemical biology | 27820797 | Nat Chem Biol | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27820797 |
Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactams. | Schoonmaker MK, Bishai WR, Lamichhane G | Journal of bacteriology | 24464457 | J Bacteriol | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24464457 |
REMap: Operon map of M. tuberculosis based on RNA sequence data. | Pelly S, Winglee K, Xia FF, Stevens RL, Bishai WR, Lamichhane G | Tuberculosis (Edinburgh, Scotland) | 27450008 | Tuberculosis (Edinb) | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27450008 |
Ldt(Mav2), a nonclassical transpeptidase and susceptibility of Mycobacterium avium to carbapenems. | Mattoo R, Lloyd EP, Kaushik A, Kumar P, Brunelle JL, Townsend CA, Lamichhane G | Future microbiology | 28555497 | Future Microbiol | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28555497 |
Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2. | Silva JR, Bishai WR, Govender T, Lamichhane G, Maguire GE, Kruger HG, Lameira J, Alves CN | Journal of biomolecular structure & dynamics | 25762064 | J Biomol Struct Dyn | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/25762064 |
Intrabacterial Metabolism Obscures the Successful Prediction of an InhA Inhibitor of Mycobacterium tuberculosis. | Wang X, Perryman AL, Li SG, Paget SD, Stratton TP, Lemenze A, Olson AJ, Ekins S, Kumar P, Freundlich JS | ACS infectious diseases | 31625383 | ACS Infect Dis | 2019 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/31625383 |
Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development. | Moraes GL, Gomes GC, Monteiro de Sousa PR, Alves CN, Govender T, Kruger HG, Maguire GE, Lamichhane G, Lameira J | Tuberculosis (Edinburgh, Scotland) | 25701501 | Tuberculosis (Edinb) | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25701501 |
Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis. | Brammer Basta LA, Ghosh A, Pan Y, Jakoncic J, Lloyd EP, Townsend CA, Lamichhane G, Bianchet MA | The Journal of biological chemistry | 26304120 | J Biol Chem | 2015 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/26304120 |
Carbapenems and Rifampin Exhibit Synergy against Mycobacterium tuberculosis and Mycobacterium abscessus. | Kaushik A, Makkar N, Pandey P, Parrish N, Singh U, Lamichhane G | Antimicrobial agents and chemotherapy | 26259792 | Antimicrob Agents Chemother | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26259792 |
Targeting the cell wall of Mycobacterium tuberculosis: structure and mechanism of L,D-transpeptidase 2. | Erdemli SB, Gupta R, Bishai WR, Lamichhane G, Amzel LM, Bianchet MA | Structure (London, England : 1993) | 23103390 | Structure | 2012 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/23103390 |
Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt(Mt2) by biapenem and tebipenem. | Bianchet MA, Pan YH, Basta LAB, Saavedra H, Lloyd EP, Kumar P, Mattoo R, Townsend CA, Lamichhane G | BMC biochemistry | 28545389 | BMC Biochem | 2017 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/28545389 |
An evolved oxazolidinone with selective potency against Mycobacterium tuberculosis and gram positive bacteria. | Kaushik A, Heuer AM, Bell DT, Culhane JC, Ebner DC, Parrish N, Ippoliti JT, Lamichhane G | Bioorganic & medicinal chemistry letters | 27329794 | Bioorg Med Chem Lett | 2016 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/27329794 |
A screen for non-coding RNA in Mycobacterium tuberculosis reveals a cAMP-responsive RNA that is expressed during infection. | Pelly S, Bishai WR, Lamichhane G | Gene | 22446041 | Gene | 2012 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/22446041 |
Mutation in an Unannotated Protein Confers Carbapenem Resistance in Mycobacterium tuberculosis. | Kumar P, Kaushik A, Bell DT, Chauhan V, Xia F, Stevens RL, Lamichhane G | Antimicrobial agents and chemotherapy | 28069655 | Antimicrob Agents Chemother | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28069655 |
In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis. | Kaushik A, Ammerman NC, Tasneen R, Story-Roller E, Dooley KE, Dorman SE, Nuermberger EL, Lamichhane G | The Journal of antimicrobial chemotherapy | 28575382 | J Antimicrob Chemother | 2017 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/28575382 |
Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins. | Kumar P, Chauhan V, Silva JRA, Lameira J, d'Andrea FB, Li SG, Ginell SL, Freundlich JS, Alves CN, Bailey S, Cohen KA, Lamichhane G | Antimicrobial agents and chemotherapy | 28760902 | Antimicrob Agents Chemother | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28760902 |
A virtual screen discovers novel, fragment-sized inhibitors of Mycobacterium tuberculosis InhA. | Perryman AL, Yu W, Wang X, Ekins S, Forli S, Li SG, Freundlich JS, Tonge PJ, Olson AJ | Journal of chemical information and modeling | 25636146 | J Chem Inf Model | 2015 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/25636146 |
Role of the Cys154Arg Substitution in Ribosomal Protein L3 in Oxazolidinone Resistance in Mycobacterium tuberculosis. | Makafe GG, Cao Y, Tan Y, Julius M, Liu Z, Wang C, Njire MM, Cai X, Liu T, Wang B, Pang W, Tan S, Zhang B, Yew WW, Lamichhane G, Guo J, Zhang T | Antimicrobial agents and chemotherapy | 26953211 | Antimicrob Agents Chemother | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26953211 |
Pooled ChIP-Seq Links Variation in Transcription Factor Binding to Complex Disease Risk. | Tehranchi AK, Myrthil M, Martin T, Hie BL, Golan D, Fraser HB | Cell | 27087447 | Cell | 2016 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/27087447 |
Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment. | Braas D, Ahler E, Tam B, Nathanson D, Riedinger M, Benz MR, Smith KB, Eilber FC, Witte ON, Tap WD, Wu H, Christofk HR | Cancer discovery | 23230188 | Cancer Discov | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23230188 |
MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. | Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PAL, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, Dubinett SM, Critchlow SE, Kurdistani SK, Goodglick L, Braas D, Graeber TG, Christofk HR | Cell reports | 26876179 | Cell Rep | 2016 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/26876179 |
MYC-induced reprogramming of glutamine catabolism supports optimal virus replication. | Thai M, Thaker SK, Feng J, Du Y, Hu H, Ting Wu T, Graeber TG, Braas D, Christofk HR | Nature communications | 26561297 | Nat Commun | 2015 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/26561297 |
Doxycycline alters metabolism and proliferation of human cell lines. | Ahler E, Sullivan WJ, Cass A, Braas D, York AG, Bensinger SJ, Graeber TG, Christofk HR | PloS one | 23741339 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23741339 |
Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication. | Thai M, Graham NA, Braas D, Nehil M, Komisopoulou E, Kurdistani SK, McCormick F, Graeber TG, Christofk HR | Cell metabolism | 24703700 | Cell Metab | 2014 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24703700 |
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. | Krall AS, Xu S, Graeber TG, Braas D, Christofk HR | Nature communications | 27126896 | Nat Commun | 2016 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/27126896 |
The ecological basis of morphogenesis: branching patterns in swarming colonies of bacteria. | Deng P, de Vargas Roditi L, van Ditmarsch D, Xavier JB | New journal of physics | 24587694 | New J Phys | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24587694 |
Tumour-stromal interactions generate emergent persistence in collective cancer cell migration. | Chang WK, Carmona-Fontaine C, Xavier JB | Interface focus | 24511381 | Interface Focus | 2013 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/24511381 |
Cell-Size Homeostasis and the Incremental Rule in a Bacterial Pathogen. | Deforet M, van Ditmarsch D, Xavier JB | Biophysical journal | 26244734 | Biophys J | 2015 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/26244734 |
Integration of Metabolic and Quorum Sensing Signals Governing the Decision to Cooperate in a Bacterial Social Trait. | Boyle KE, Monaco H, van Ditmarsch D, Deforet M, Xavier JB | PLoS computational biology | 26102206 | PLoS Comput Biol | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/26102206 |
Towards predictive models of the human gut microbiome. | Bucci V, Xavier JB | Journal of molecular biology | 24727124 | J Mol Biol | 2014 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/24727124 |
Social interaction, noise and antibiotic-mediated switches in the intestinal microbiota. | Bucci V, Bradde S, Biroli G, Xavier JB | PLoS computational biology | 22577356 | PLoS Comput Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22577356 |
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile. | Buffie CG, Bucci V, Stein RR, McKenney PT, Ling L, Gobourne A, No D, Liu H, Kinnebrew M, Viale A, Littmann E, van den Brink MR, Jenq RR, Taur Y, Sander C, Cross JR, Toussaint NC, Xavier JB, Pamer EG | Nature | 25337874 | Nature | 2015 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/25337874 |
Cutting through the complexity of cell collectives. | Nadell CD, Bucci V, Drescher K, Levin SA, Bassler BL, Xavier JB | Proceedings. Biological sciences | 23363630 | Proc Biol Sci | 2013 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/23363630 |
Turning ecology and evolution against cancer. | Korolev KS, Xavier JB, Gore J | Nature reviews. Cancer | 24739582 | Nat Rev Cancer | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24739582 |
Multilevel selection analysis of a microbial social trait. | de Vargas Roditi L, Boyle KE, Xavier JB | Molecular systems biology | 23959025 | Mol Syst Biol | 2013 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/23959025 |
Emergence of spatial structure in the tumor microenvironment due to the Warburg effect. | Carmona-Fontaine C, Bucci V, Akkari L, Deforet M, Joyce JA, Xavier JB | Proceedings of the National Academy of Sciences of the United States of America | 24218566 | Proc Natl Acad Sci U S A | 2013 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/24218566 |
Sociomicrobiology and Pathogenic Bacteria. | Xavier JB | Microbiology spectrum | 27337482 | Microbiol Spectr | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27337482 |
Convergent evolution of hyperswarming leads to impaired biofilm formation in pathogenic bacteria. | van Ditmarsch D, Boyle KE, Sakhtah H, Oyler JE, Nadell CD, Déziel É, Dietrich LE, Xavier JB | Cell reports | 23954787 | Cell Rep | 2013 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/23954787 |
Exploiting social evolution in biofilms. | Boyle KE, Heilmann S, van Ditmarsch D, Xavier JB | Current opinion in microbiology | 23357558 | Curr Opin Microbiol | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23357558 |
Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation. | Taur Y, Xavier JB, Lipuma L, Ubeda C, Goldberg J, Gobourne A, Lee YJ, Dubin KA, Socci ND, Viale A, Perales MA, Jenq RR, van den Brink MR, Pamer EG | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 22718773 | Clin Infect Dis | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22718773 |
Hyperswarming adaptations in a bacterium improve collective motility without enhancing single cell motility. | Deforet M, van Ditmarsch D, Carmona-Fontaine C, Xavier JB | Soft matter | 24622509 | Soft Matter | 2014 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/24622509 |
Ecological modeling from time-series inference: insight into dynamics and stability of intestinal microbiota. | Stein RR, Bucci V, Toussaint NC, Buffie CG, Rätsch G, Pamer EG, Sander C, Xavier JB | PLoS computational biology | 24348232 | PLoS Comput Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24348232 |
Metabolism and the Evolution of Social Behavior. | Boyle KE, Monaco HT, Deforet M, Yan J, Wang Z, Rhee K, Xavier JB | Molecular biology and evolution | 28595344 | Mol Biol Evol | 2017 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/28595344 |
Facultative control of matrix production optimizes competitive fitness in Pseudomonas aeruginosa PA14 biofilm models. | Madsen JS, Lin YC, Squyres GR, Price-Whelan A, de Santiago Torio A, Song A, Cornell WC, Sørensen SJ, Xavier JB, Dietrich LE | Applied and environmental microbiology | 26431965 | Appl Environ Microbiol | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26431965 |
Human symbionts inject and neutralize antibacterial toxins to persist in the gut. | Wexler AG, Bao Y, Whitney JC, Bobay LM, Xavier JB, Schofield WB, Barry NA, Russell AB, Tran BQ, Goo YA, Goodlett DR, Ochman H, Mougous JD, Goodman AL | Proceedings of the National Academy of Sciences of the United States of America | 26957597 | Proc Natl Acad Sci U S A | 2016 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/26957597 |
Corynebacterium glutamicum Metabolic Engineering with CRISPR Interference (CRISPRi). | Cleto S, Jensen JV, Wendisch VF, Lu TK | ACS synthetic biology | 26829286 | ACS Synth Biol | 2016 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/26829286 |
Synthetic biology. Genomically encoded analog memory with precise in vivo DNA writing in living cell populations. | Farzadfard F, Lu TK | Science (New York, N.Y.) | 25395541 | Science | 2014 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/25395541 |
Synthetic analog and digital circuits for cellular computation and memory. | Purcell O, Lu TK | Current opinion in biotechnology | 24794536 | Curr Opin Biotechnol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24794536 |
Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. | Nissim L, Perli SD, Fridkin A, Perez-Pinera P, Lu TK | Molecular cell | 24837679 | Mol Cell | 2014 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/24837679 |
Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas. | Farzadfard F, Perli SD, Lu TK | ACS synthetic biology | 23977949 | ACS Synth Biol | 2013 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/23977949 |
Synthetic biology of antimicrobial discovery. | Zakeri B, Lu TK | ACS synthetic biology | 23654251 | ACS Synth Biol | 2013 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/23654251 |
Synthetic mixed-signal computation in living cells. | Rubens JR, Selvaggio G, Lu TK | Nature communications | 27255669 | Nat Commun | 2016 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/27255669 |
Single-molecule detection of protein efflux from microorganisms using fluorescent single-walled carbon nanotube sensor arrays. | Landry MP, Ando H, Chen AY, Cao J, Kottadiel VI, Chio L, Yang D, Dong J, Lu TK, Strano MS | Nature nanotechnology | 28114298 | Nat Nanotechnol | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28114298 |
Hydrogel-based biocontainment of bacteria for continuous sensing and computation. | Tang TC, Tham E, Liu X, Yehl K, Rovner AJ, Yuk H, de la Fuente-Nunez C, Isaacs FJ, Zhao X, Lu TK | Nature chemical biology | 33820990 | Nat Chem Biol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33820990 |
Natural combinatorial genetics and prolific polyamine production enable siderophore diversification in Serratia plymuthica. | Cleto S, Haslinger K, Prather KLJ, Lu TK | BMC biology | 33722216 | BMC Biol | 2021 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/33722216 |
Surface charge-switching polymeric nanoparticles for bacterial cell wall-targeted delivery of antibiotics. | Radovic-Moreno AF, Lu TK, Puscasu VA, Yoon CJ, Langer R, Farokhzad OC | ACS nano | 22471841 | ACS Nano | 2012 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/22471841 |
Engineering living functional materials. | Chen AY, Zhong C, Lu TK | ACS synthetic biology | 25592034 | ACS Synth Biol | 2015 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/25592034 |
Synthetic recombinase-based state machines in living cells. | Roquet N, Soleimany AP, Ferris AC, Aaronson S, Lu TK | Science (New York, N.Y.) | 27463678 | Science | 2016 Jul 22 | https://www.ncbi.nlm.nih.gov/pubmed/27463678 |
A Modular Toolkit for Generating Pichia pastoris Secretion Libraries. | Obst U, Lu TK, Sieber V | ACS synthetic biology | 28252957 | ACS Synth Biol | 2017 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/28252957 |
Advancing bacteriophage-based microbial diagnostics with synthetic biology. | Lu TK, Bowers J, Koeris MS | Trends in biotechnology | 23608522 | Trends Biotechnol | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23608522 |
Strong underwater adhesives made by self-assembling multi-protein nanofibres. | Zhong C, Gurry T, Cheng AA, Downey J, Deng Z, Stultz CM, Lu TK | Nature nanotechnology | 25240674 | Nat Nanotechnol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25240674 |
Rule-based design of synthetic transcription factors in eukaryotes. | Purcell O, Peccoud J, Lu TK | ACS synthetic biology | 24933274 | ACS Synth Biol | 2014 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/24933274 |
Synthetic biology: an emerging engineering discipline. | Cheng AA, Lu TK | Annual review of biomedical engineering | 22577777 | Annu Rev Biomed Eng | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22577777 |
Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing. | Ando H, Lemire S, Pires DP, Lu TK | Cell systems | 26973885 | Cell Syst | 2015 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/26973885 |
Foundations and Emerging Paradigms for Computing in Living Cells. | Ma KC, Perli SD, Lu TK | Journal of molecular biology | 26908220 | J Mol Biol | 2016 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/26908220 |
Engineering genetic circuits that compute and remember. | Siuti P, Yazbek J, Lu TK | Nature protocols | 24810038 | Nat Protoc | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24810038 |
Digital and analog gene circuits for biotechnology. | Roquet N, Lu TK | Biotechnology journal | 24677719 | Biotechnol J | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24677719 |
Massively parallel high-order combinatorial genetics in human cells. | Wong AS, Choi GC, Cheng AA, Purcell O, Lu TK | Nature biotechnology | 26280411 | Nat Biotechnol | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26280411 |
DNA nanotechnology: new adventures for an old warhorse. | Zakeri B, Lu TK | Current opinion in chemical biology | 26056949 | Curr Opin Chem Biol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26056949 |
A synthetic biology framework for programming eukaryotic transcription functions. | Khalil AS, Lu TK, Bashor CJ, Ramirez CL, Pyenson NC, Joung JK, Collins JJ | Cell | 22863014 | Cell | 2012 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/22863014 |
Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis. | Yehl K, Lemire S, Yang AC, Ando H, Mimee M, Torres MT, de la Fuente-Nunez C, Lu TK | Cell | 31585083 | Cell | 2019 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/31585083 |
Towards a whole-cell modeling approach for synthetic biology. | Purcell O, Jain B, Karr JR, Covert MW, Lu TK | Chaos (Woodbury, N.Y.) | 23822510 | Chaos | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23822510 |
Enhancing phage therapy through synthetic biology and genome engineering. | Lenneman BR, Fernbach J, Loessner MJ, Lu TK, Kilcher S | Current opinion in biotechnology | 33310655 | Curr Opin Biotechnol | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33310655 |
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM. | Wong AS, Choi GC, Cui CH, Pregernig G, Milani P, Adam M, Perli SD, Kazer SW, Gaillard A, Hermann M, Shalek AK, Fraenkel E, Lu TK | Proceedings of the National Academy of Sciences of the United States of America | 26864203 | Proc Natl Acad Sci U S A | 2016 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26864203 |
Programming a Human Commensal Bacterium, Bacteroides thetaiotaomicron, to Sense and Respond to Stimuli in the Murine Gut Microbiota. | Mimee M, Tucker AC, Voigt CA, Lu TK | Cell systems | 26918244 | Cell Syst | 2015 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/26918244 |
Gene networks that compensate for crosstalk with crosstalk. | Müller IE, Rubens JR, Jun T, Graham D, Xavier R, Lu TK | Nature communications | 31492904 | Nat Commun | 2019 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/31492904 |
Synthesis and patterning of tunable multiscale materials with engineered cells. | Chen AY, Deng Z, Billings AN, Seker UO, Lu MY, Citorik RJ, Zakeri B, Lu TK | Nature materials | 24658114 | Nat Mater | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24658114 |
Enhanced killing of antibiotic-resistant bacteria enabled by massively parallel combinatorial genetics. | Cheng AA, Ding H, Lu TK | Proceedings of the National Academy of Sciences of the United States of America | 25114216 | Proc Natl Acad Sci U S A | 2014 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/25114216 |
Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases. | Citorik RJ, Mimee M, Lu TK | Nature biotechnology | 25240928 | Nat Biotechnol | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25240928 |
Bacteriophage-based synthetic biology for the study of infectious diseases. | Citorik RJ, Mimee M, Lu TK | Current opinion in microbiology | 24997401 | Curr Opin Microbiol | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24997401 |
Synthetic Biogenesis of Bacterial Amyloid Nanomaterials with Tunable Inorganic-Organic Interfaces and Electrical Conductivity. | Seker UO, Chen AY, Citorik RJ, Lu TK | ACS synthetic biology | 27794590 | ACS Synth Biol | 2017 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/27794590 |
Multiplexed Sequence Encoding: A Framework for DNA Communication. | Zakeri B, Carr PA, Lu TK | PloS one | 27050646 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27050646 |
Genetically Engineered Phages: a Review of Advances over the Last Decade. | Pires DP, Cleto S, Sillankorva S, Azeredo J, Lu TK | Microbiology and molecular biology reviews : MMBR | 27250768 | Microbiol Mol Biol Rev | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27250768 |
Complete Genome Sequence of Pseudomonas aeruginosa Phage vB_PaeM_CEB_DP1. | Pires DP, Sillankorva S, Kropinski AM, Lu TK, Azeredo J | Genome announcements | 26404589 | Genome Announc | 2015 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/26404589 |
Microbiome therapeutics - Advances and challenges. | Mimee M, Citorik RJ, Lu TK | Advanced drug delivery reviews | 27158095 | Adv Drug Deliv Rev | 2016 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/27158095 |
Full-colour Jabuticaba-like nanostructures via the multiplex and orthogonal self-assembly of protein-conjugated quantum dots with engineered biofilms. | Deng Z, Chen AY, Zakeri B, Zhong C, Lu TK | Materials horizons | 36786820 | Mater Horiz | 2023 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/36786820 |
TeloPCR-seq: a high-throughput sequencing approach for telomeres. | Bennett HW, Liu N, Hu Y, King MC | FEBS letters | 27714790 | FEBS Lett | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27714790 |
A role for nuclear envelope-bridging complexes in homology-directed repair. | Swartz RK, Rodriguez EC, King MC | Molecular biology of the cell | 24943839 | Mol Biol Cell | 2014 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/24943839 |
A model for coordinating nuclear mechanics and membrane remodeling to support nuclear integrity. | King MC, Lusk CP | Current opinion in cell biology | 27031045 | Curr Opin Cell Biol | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27031045 |
A quality control mechanism linking meiotic success to release of ascospores. | Guo H, King MC | PloS one | 24312672 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24312672 |
Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks. | Leland BA, Chen AC, Zhao AY, Wharton RC, King MC | eLife | 29697047 | Elife | 2018 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/29697047 |
Forces, fluctuations, and self-organization in the nucleus. | Pederson T, King MC, Marko JF | Molecular biology of the cell | 26543199 | Mol Biol Cell | 2015 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/26543199 |
The KASH protein Kms2 coordinates mitotic remodeling of the spindle pole body. | Wälde S, King MC | Journal of cell science | 24963130 | J Cell Sci | 2014 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/24963130 |
Improved Determination of Subnuclear Position Enabled by Three-Dimensional Membrane Reconstruction. | Zhao Y, Schreiner SM, Koo PK, Colombi P, King MC, Mochrie SG | Biophysical journal | 27410730 | Biophys J | 2016 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/27410730 |
RNA-DNA Hybrids Support Recombination-Based Telomere Maintenance in Fission Yeast. | Hu Y, Bennett HW, Liu N, Moravec M, Williams JF, Azzalin CM, King MC | Genetics | 31405990 | Genetics | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31405990 |
TERRA promotes telomerase-mediated telomere elongation in Schizosaccharomyces pombe. | Moravec M, Wischnewski H, Bah A, Hu Y, Liu N, Lafranchi L, King MC, Azzalin CM | EMBO reports | 27154402 | EMBO Rep | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27154402 |
Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates. | Tillo SE, Xiong WH, Takahashi M, Miao S, Andrade AL, Fortin DA, Yang G, Qin M, Smoody BF, Stork PJS, Zhong H | Cell reports | 28423323 | Cell Rep | 2017 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/28423323 |
Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins. | Fortin DA, Tillo SE, Yang G, Rah JC, Melander JB, Bai S, Soler-Cedeño O, Qin M, Zemelman BV, Guo C, Mao T, Zhong H | The Journal of neuroscience : the official journal of the Society for Neuroscience | 25505322 | J Neurosci | 2014 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/25505322 |
Subdiffractive microscopy: techniques, applications, and challenges. | Long BR, Robinson DC, Zhong H | Wiley interdisciplinary reviews. Systems biology and medicine | 24443323 | Wiley Interdiscip Rev Syst Biol Med | 2014 Mar-Apr | https://www.ncbi.nlm.nih.gov/pubmed/24443323 |
Applying superresolution localization-based microscopy to neurons. | Zhong H | Synapse (New York, N.Y.) | 25648102 | Synapse | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25648102 |
A comprehensive thalamocortical projection map at the mesoscopic level. | Hunnicutt BJ, Long BR, Kusefoglu D, Gertz KJ, Zhong H, Mao T | Nature neuroscience | 25086607 | Nat Neurosci | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25086607 |
A comprehensive excitatory input map of the striatum reveals novel functional organization. | Hunnicutt BJ, Jongbloets BC, Birdsong WT, Gertz KJ, Zhong H, Mao T | eLife | 27892854 | Elife | 2016 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/27892854 |
Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality. | Rangaraju S, Solis GM, Thompson RC, Gomez-Amaro RL, Kurian L, Encalada SE, Niculescu AB 3rd, Salomon DR, Petrascheck M | eLife | 26623667 | Elife | 2015 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/26623667 |
The aging transcriptome: read between the lines. | Perez-Gomez A, Buxbaum JN, Petrascheck M | Current opinion in neurobiology | 32563038 | Curr Opin Neurobiol | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32563038 |
High-throughput small-molecule screening in Caenorhabditis elegans. | Rangaraju S, Solis GM, Petrascheck M | Methods in molecular biology (Clifton, N.J.) | 25618342 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25618342 |
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. | Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J | Nature | 24828042 | Nature | 2014 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/24828042 |
Mood, stress and longevity: convergence on ANK3. | Rangaraju S, Levey DF, Nho K, Jain N, Andrews KD, Le-Niculescu H, Salomon DR, Saykin AJ, Petrascheck M, Niculescu AB | Molecular psychiatry | 27217151 | Mol Psychiatry | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27217151 |
Atypical antidepressants extend lifespan of Caenorhabditis elegans by activation of a non-cell-autonomous stress response. | Rangaraju S, Solis GM, Andersson SI, Gomez-Amaro RL, Kardakaris R, Broaddus CD, Niculescu AB 3rd, Petrascheck M | Aging cell | 26255886 | Aging Cell | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26255886 |
Measuring Food Intake and Nutrient Absorption in Caenorhabditis elegans. | Gomez-Amaro RL, Valentine ER, Carretero M, LeBoeuf SE, Rangaraju S, Broaddus CD, Solis GM, Williamson JR, Petrascheck M | Genetics | 25903497 | Genetics | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25903497 |
Measuring Caenorhabditis elegans life span in 96 well microtiter plates. | Solis GM, Petrascheck M | Journal of visualized experiments : JoVE | 21445049 | J Vis Exp | 2011 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/21445049 |
A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia. | Perez-Gomez A, Carretero M, Weber N, Peterka V, To A, Titova V, Solis G, Osborn O, Petrascheck M | Nature communications | 30532051 | Nat Commun | 2018 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/30532051 |
Computational Analysis of Lifespan Experiment Reproducibility. | Petrascheck M, Miller DL | Frontiers in genetics | 28713422 | Front Genet | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28713422 |
Proteostasis is differentially modulated by inhibition of translation initiation or elongation. | Clay KJ, Yang Y, Clark C, Petrascheck M | eLife | 37795690 | Elife | 2023 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/37795690 |
A pharmacological network for lifespan extension in Caenorhabditis elegans. | Ye X, Linton JM, Schork NJ, Buck LB, Petrascheck M | Aging cell | 24134630 | Aging Cell | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24134630 |
Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms. | Solis GM, Kardakaris R, Valentine ER, Bar-Peled L, Chen AL, Blewett MM, McCormick MA, Williamson JR, Kennedy B, Cravatt BF, Petrascheck M | eLife | 30479271 | Elife | 2018 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/30479271 |
Pharmacological classes that extend lifespan of Caenorhabditis elegans. | Carretero M, Gomez-Amaro RL, Petrascheck M | Frontiers in genetics | 25784926 | Front Genet | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25784926 |
A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease. | Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW Jr, Birnbaumer L, Staruschenko A | Journal of the American Society of Nephrology : JASN | 29793963 | J Am Soc Nephrol | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29793963 |
Chronic central serotonin depletion attenuates ventilation and body temperature in young but not adult Tph2 knockout rats. | Kaplan K, Echert AE, Massat B, Puissant MM, Palygin O, Geurts AM, Hodges MR | Journal of applied physiology (Bethesda, Md. : 1985) | 26869713 | J Appl Physiol (1985) | 2016 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/26869713 |
2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research. | Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A, International Committee on Standardized Genetic Nomenclature for Mice, Rat Genome and Nomenclature Committee | Journal of cardiovascular translational research | 25920443 | J Cardiovasc Transl Res | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25920443 |
p66Shc regulates renal vascular tone in hypertension-induced nephropathy. | Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW Jr, Geurts AM, Staruschenko A, Imig JD, Sorokin A | The Journal of clinical investigation | 27270176 | J Clin Invest | 2016 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/27270176 |
Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure. | Kuijk EW, Rasmussen S, Blokzijl F, Huch M, Gehart H, Toonen P, Begthel H, Clevers H, Geurts AM, Cuppen E | Scientific reports | 26915950 | Sci Rep | 2016 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/26915950 |
Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats. | Fan F, Geurts AM, Pabbidi MR, Smith SV, Harder DR, Jacob H, Roman RJ | PloS one | 25397684 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25397684 |
Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cells. | Hegan PS, Ostertag E, Geurts AM, Mooseker MS | Cytoskeleton (Hoboken, N.J.) | 26446290 | Cytoskeleton (Hoboken) | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26446290 |
Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection. | Mitzelfelt KA, McDermott-Roe C, Grzybowski MN, Marquez M, Kuo CT, Riedel M, Lai S, Choi MJ, Kolander KD, Helbling D, Dimmock DP, Battle MA, Jou CJ, Tristani-Firouzi M, Verbsky JW, Benjamin IJ, Geurts AM | Stem cell reports | 28238794 | Stem Cell Reports | 2017 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/28238794 |
Identifying multiple causative genes at a single GWAS locus. | Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C | Genome research | 24006081 | Genome Res | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24006081 |
Rab38 modulates proteinuria in model of hypertension-associated renal disease. | Rangel-Filho A, Lazar J, Moreno C, Geurts A, Jacob HJ | Journal of the American Society of Nephrology : JASN | 23291471 | J Am Soc Nephrol | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23291471 |
The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility. | Mitzelfelt KA, Limphong P, Choi MJ, Kondrat FD, Lai S, Kolander KD, Kwok WM, Dai Q, Grzybowski MN, Zhang H, Taylor GM, Lui Q, Thao MT, Hudson JA, Barresi R, Bushby K, Jungbluth H, Wraige E, Geurts AM, Benesch JL, Riedel M, Christians ES, Minella AC, Benjamin IJ | The Journal of biological chemistry | 27226619 | J Biol Chem | 2016 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/27226619 |
Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats. | Geurts AM, Mattson DL, Liu P, Cabacungan E, Skelton MM, Kurth TM, Yang C, Endres BT, Klotz J, Liang M, Cowley AW Jr | Hypertension (Dallas, Tex. : 1979) | 25452472 | Hypertension | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25452472 |
CXM: a new tool for mapping breast cancer risk in the tumor microenvironment. | Flister MJ, Endres BT, Rudemiller N, Sarkis AB, Santarriaga S, Roy I, Lemke A, Geurts AM, Moreno C, Ran S, Tsaih SW, De Pons J, Carlson DF, Tan W, Fahrenkrug SC, Lazarova Z, Lazar J, North PE, LaViolette PS, Dwinell MB, Shull JD, Jacob HJ | Cancer research | 25172839 | Cancer Res | 2014 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/25172839 |
Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. | Endres BT, Priestley JR, Palygin O, Flister MJ, Hoffman MJ, Weinberg BD, Grzybowski M, Lombard JH, Staruschenko A, Moreno C, Jacob HJ, Geurts AM | Proceedings of the National Academy of Sciences of the United States of America | 25136115 | Proc Natl Acad Sci U S A | 2014 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/25136115 |
Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. | Carlson DF, Geurts AM, Garbe JR, Park CW, Rangel-Filho A, O'Grady SM, Jacob HJ, Steer CJ, Largaespada DA, Fahrenkrug SC | Transgenic research | 20352328 | Transgenic Res | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/20352328 |
Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension. | Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA | Purinergic signalling | 26385692 | Purinergic Signal | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26385692 |
Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons. | Ivics Z, Mátés L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, Bösze Z, Geurts A, Pravenec M, Rülicke T, Izsvák Z | Nature protocols | 24625778 | Nat Protoc | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24625778 |
Essential role of Kir5.1 channels in renal salt handling and blood pressure control. | Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Pochynyuk OM, Jacob HJ, Geurts AM, Hodges MR, Staruschenko A | JCI insight | 28931751 | JCI Insight | 2017 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/28931751 |
Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. | Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M | Journal of the American Heart Association | 26888427 | J Am Heart Assoc | 2016 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/26888427 |
The NRF2 knockout rat: a new animal model to study endothelial dysfunction, oxidant stress, and microvascular rarefaction. | Priestley JR, Kautenburg KE, Casati MC, Endres BT, Geurts AM, Lombard JH | American journal of physiology. Heart and circulatory physiology | 26637559 | Am J Physiol Heart Circ Physiol | 2016 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/26637559 |
Intravital imaging of the kidney in a rat model of salt-sensitive hypertension. | Endres BT, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Kamocka MM, McDermott-Roe C, Staruschenko A, Molitoris BA, Geurts AM, Palygin O | American journal of physiology. Renal physiology | 28404591 | Am J Physiol Renal Physiol | 2017 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/28404591 |
Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics. | Parker CC, Chen H, Flagel SB, Geurts AM, Richards JB, Robinson TE, Solberg Woods LC, Palmer AA | Neuropharmacology | 23791960 | Neuropharmacology | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23791960 |
Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats. | McPherson KC, Taylor L, Johnson AC, Didion SP, Geurts AM, Garrett MR, Williams JM | American journal of physiology. Renal physiology | 27465994 | Am J Physiol Renal Physiol | 2016 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/27465994 |
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. | Katter K, Geurts AM, Hoffmann O, Mátés L, Landa V, Hiripi L, Moreno C, Lazar J, Bashir S, Zidek V, Popova E, Jerchow B, Becker K, Devaraj A, Walter I, Grzybowksi M, Corbett M, Filho AR, Hodges MR, Bader M, Ivics Z, Jacob HJ, Pravenec M, Bosze Z, Rülicke T, Izsvák Z | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 23195032 | FASEB J | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23195032 |
Nitric oxide production by glomerular podocytes. | Palygin O, Ilatovskaya DV, Levchenko V, Endres BT, Geurts AM, Staruschenko A | Nitric oxide : biology and chemistry | 29128399 | Nitric Oxide | 2018 Jan 30 | https://www.ncbi.nlm.nih.gov/pubmed/29128399 |
Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta. | Endres BT, Staruschenko A, Schulte M, Geurts AM, Palygin O | Journal of visualized experiments : JoVE | 26132549 | J Vis Exp | 2015 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/26132549 |
Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat. | Fan F, Geurts AM, Murphy SR, Pabbidi MR, Jacob HJ, Roman RJ | American journal of physiology. Regulatory, integrative and comparative physiology | 25540098 | Am J Physiol Regul Integr Comp Physiol | 2015 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/25540098 |
A monoclonal antibody that targets a NaV1.7 channel voltage sensor for pain and itch relief. | Lee JH, Park CK, Chen G, Han Q, Xie RG, Liu T, Ji RR, Lee SY | Cell | 24856969 | Cell | 2014 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/24856969 |
Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin. | Wang C, Chung BC, Yan H, Lee SY, Pitt GS | Structure (London, England : 1993) | 22705208 | Structure | 2012 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/22705208 |
Current view on regulation of voltage-gated sodium channels by calcium and auxiliary proteins. | Pitt GS, Lee SY | Protein science : a publication of the Protein Society | 27262167 | Protein Sci | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27262167 |
Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å. | Johnson ZL, Cheong CG, Lee SY | Nature | 22407322 | Nature | 2012 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/22407322 |
Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation. | Wang C, Chung BC, Yan H, Wang HG, Lee SY, Pitt GS | Nature communications | 25232683 | Nat Commun | 2014 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/25232683 |
Cryo-electron microscopy structure of the TRPV2 ion channel. | Zubcevic L, Herzik MA Jr, Chung BC, Liu Z, Lander GC, Lee SY | Nature structural & molecular biology | 26779611 | Nat Struct Mol Biol | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26779611 |
Variability in a Short Tandem Repeat Mediates Complex Epistatic Interactions in Arabidopsis thaliana. | Press MO, Queitsch C | Genetics | 27866166 | Genetics | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27866166 |
The Mechanistic Underpinnings of an ago1-Mediated, Environmentally Dependent, and Stochastic Phenotype. | Mason GA, Lemus T, Queitsch C | Plant physiology | 26872948 | Plant Physiol | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26872948 |
Background-dependent effects of polyglutamine variation in the Arabidopsis thaliana gene ELF3. | Undurraga SF, Press MO, Legendre M, Bujdoso N, Bale J, Wang H, Davis SJ, Verstrepen KJ, Queitsch C | Proceedings of the National Academy of Sciences of the United States of America | 23129635 | Proc Natl Acad Sci U S A | 2012 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/23129635 |
Molecular mechanisms governing differential robustness of development and environmental responses in plants. | Lachowiec J, Queitsch C, Kliebenstein DJ | Annals of botany | 26473020 | Ann Bot | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26473020 |
Redundancy, Feedback, and Robustness in the Arabidopsis thaliana BZR/BEH Gene Family. | Lachowiec J, Mason GA, Schultz K, Queitsch C | Frontiers in genetics | 30542366 | Front Genet | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30542366 |
It's not magic - Hsp90 and its effects on genetic and epigenetic variation. | Zabinsky RA, Mason GA, Queitsch C, Jarosz DF | Seminars in cell & developmental biology | 29807130 | Semin Cell Dev Biol | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29807130 |
Molecular mechanisms of robustness in plants. | Lempe J, Lachowiec J, Sullivan AM, Queitsch C | Current opinion in plant biology | 23279801 | Curr Opin Plant Biol | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23279801 |
The protein chaperone HSP90 can facilitate the divergence of gene duplicates. | Lachowiec J, Lemus T, Thomas JH, Murphy PJ, Nemhauser JL, Queitsch C | Genetics | 23410833 | Genetics | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23410833 |
Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. | Xia J, Chiu LY, Nehring RB, Bravo Núñez MA, Mei Q, Perez M, Zhai Y, Fitzgerald DM, Pribis JP, Wang Y, Hu CW, Powell RT, LaBonte SA, Jalali A, Matadamas Guzmán ML, Lentzsch AM, Szafran AT, Joshi MC, Richters M, Gibson JL, Frisch RL, Hastings PJ, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C, Miller KM, Rosenberg SM | Cell | 30633903 | Cell | 2019 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/30633903 |
Corrigendum: MIPSTR: a method for multiplex genotyping of germline and somatic STR variation across many individuals. | Carlson KD, Sudmant PH, Press MO, Eichler EE, Shendure J, Queitsch C | Genome research | 26240161 | Genome Res | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26240161 |
Evolutionary assembly patterns of prokaryotic genomes. | Press MO, Queitsch C, Borenstein E | Genome research | 27197212 | Genome Res | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27197212 |
The overdue promise of short tandem repeat variation for heritability. | Press MO, Carlson KD, Queitsch C | Trends in genetics : TIG | 25182195 | Trends Genet | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25182195 |
Hsp90 promotes kinase evolution. | Lachowiec J, Lemus T, Borenstein E, Queitsch C | Molecular biology and evolution | 25246701 | Mol Biol Evol | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25246701 |
Lessons from model organisms: phenotypic robustness and missing heritability in complex disease. | Queitsch C, Carlson KD, Girirajan S | PLoS genetics | 23166511 | PLoS Genet | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23166511 |
Medicine. Combating evolution to fight disease. | Rosenberg SM, Queitsch C | Science (New York, N.Y.) | 24604189 | Science | 2014 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/24604189 |
Genome-scale co-evolutionary inference identifies functions and clients of bacterial Hsp90. | Press MO, Li H, Creanza N, Kramer G, Queitsch C, Sourjik V, Borenstein E | PLoS genetics | 23874229 | PLoS Genet | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23874229 |
AGO1 and HSP90 buffer different genetic variants in Arabidopsis thaliana. | Lemus T, Mason GA, Bubb KL, Alexandre CM, Queitsch C, Cuperus JT | Genetics | 36303325 | Genetics | 2023 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/36303325 |
Massive variation of short tandem repeats with functional consequences across strains of Arabidopsis thaliana. | Press MO, McCoy RC, Hall AN, Akey JM, Queitsch C | Genome research | 29970452 | Genome Res | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29970452 |
PIF4 and ELF3 Act Independently in Arabidopsis thaliana Thermoresponsive Flowering. | Press MO, Lanctot A, Queitsch C | PloS one | 27564448 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27564448 |
GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris. | Liachko I, Youngblood RA, Tsui K, Bubb KL, Queitsch C, Raghuraman MK, Nislow C, Brewer BJ, Dunham MJ | PLoS genetics | 24603708 | PLoS Genet | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24603708 |
The conserved PFT1 tandem repeat is crucial for proper flowering in Arabidopsis thaliana. | Rival P, Press MO, Bale J, Grancharova T, Undurraga SF, Queitsch C | Genetics | 25116137 | Genetics | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25116137 |
A Genome-Wide Association Analysis Reveals Epistatic Cancellation of Additive Genetic Variance for Root Length in Arabidopsis thaliana. | Lachowiec J, Shen X, Queitsch C, Carlborg Ö | PLoS genetics | 26397943 | PLoS Genet | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26397943 |
HSP90 Contributes to Entrainment of the Arabidopsis Circadian Clock via the Morning Loop. | Davis AM, Ronald J, Ma Z, Wilkinson AJ, Philippou K, Shindo T, Queitsch C, Davis SJ | Genetics | 30337341 | Genetics | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30337341 |
MIPSTR: a method for multiplex genotyping of germline and somatic STR variation across many individuals. | Carlson KD, Sudmant PH, Press MO, Eichler EE, Shendure J, Queitsch C | Genome research | 25659649 | Genome Res | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25659649 |
REDOR NMR for drug discovery. | Cegelski L | Bioorganic & medicinal chemistry letters | 24035486 | Bioorg Med Chem Lett | 2013 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/24035486 |
Dimethyl sulfoxide and ethanol elicit increased amyloid biogenesis and amyloid-integrated biofilm formation in Escherichia coli. | Lim JY, May JM, Cegelski L | Applied and environmental microbiology | 22389366 | Appl Environ Microbiol | 2012 May | https://www.ncbi.nlm.nih.gov/pubmed/22389366 |
Cell-Based High-Throughput Screening Identifies Rifapentine as an Inhibitor of Amyloid and Biofilm Formation in Escherichia coli. | Maher MC, Lim JY, Gunawan C, Cegelski L | ACS infectious diseases | 27623312 | ACS Infect Dis | 2015 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/27623312 |
Curcumin as an amyloid-indicator dye in E. coli. | McCrate OA, Zhou X, Cegelski L | Chemical communications (Cambridge, England) | 23287899 | Chem Commun (Camb) | 2013 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/23287899 |
Sum of the parts: composition and architecture of the bacterial extracellular matrix. | McCrate OA, Zhou X, Reichhardt C, Cegelski L | Journal of molecular biology | 23827139 | J Mol Biol | 2013 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/23827139 |
Nutrient-dependent structural changes in S. aureus peptidoglycan revealed by solid-state NMR spectroscopy. | Zhou X, Cegelski L | Biochemistry | 22974326 | Biochemistry | 2012 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/22974326 |
Quantitative analysis of amyloid-integrated biofilms formed by uropathogenic Escherichia coli at the air-liquid interface. | Wu C, Lim JY, Fuller GG, Cegelski L | Biophysical journal | 22947862 | Biophys J | 2012 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/22947862 |
Disruption of Escherichia coli amyloid-integrated biofilm formation at the air-liquid interface by a polysorbate surfactant. | Wu C, Lim JY, Fuller GG, Cegelski L | Langmuir : the ACS journal of surfaces and colloids | 23259693 | Langmuir | 2013 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/23259693 |
Analysis of the Aspergillus fumigatus Biofilm Extracellular Matrix by Solid-State Nuclear Magnetic Resonance Spectroscopy. | Reichhardt C, Ferreira JA, Joubert LM, Clemons KV, Stevens DA, Cegelski L | Eukaryotic cell | 26163318 | Eukaryot Cell | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26163318 |
Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR. | Nygaard R, Romaniuk JAH, Rice DM, Cegelski L | Biophysical journal | 25809251 | Biophys J | 2015 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/25809251 |
Toward a biorelevant structure of protein kinase C bound modulators: design, synthesis, and evaluation of labeled bryostatin analogues for analysis with rotational echo double resonance NMR spectroscopy. | Loy BA, Lesser AB, Staveness D, Billingsley KL, Cegelski L, Wender PA | Journal of the American Chemical Society | 25710634 | J Am Chem Soc | 2015 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/25710634 |
Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR. | Romaniuk JA, Cegelski L | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 26370936 | Philos Trans R Soc Lond B Biol Sci | 2015 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/26370936 |
Bottom-up and top-down solid-state NMR approaches for bacterial biofilm matrix composition. | Cegelski L | Journal of magnetic resonance (San Diego, Calif. : 1997) | 25797008 | J Magn Reson | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25797008 |
Community behavior and amyloid-associated phenotypes among a panel of uropathogenic E. coli. | Lim JY, Pinkner JS, Cegelski L | Biochemical and biophysical research communications | 24239885 | Biochem Biophys Res Commun | 2014 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/24239885 |
Solid-State NMR for Bacterial Biofilms. | Reichhardt C, Cegelski L | Molecular physics | 24976646 | Mol Phys | 2014 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/24976646 |
Putative hydrogen bond to tyrosine M208 in photosynthetic reaction centers from Rhodobacter capsulatus significantly slows primary charge separation. | Saggu M, Carter B, Zhou X, Faries K, Cegelski L, Holten D, Boxer SG, Kirmaier C | The journal of physical chemistry. B | 24902471 | J Phys Chem B | 2014 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/24902471 |
Characterization of the Vibrio cholerae extracellular matrix: a top-down solid-state NMR approach. | Reichhardt C, Fong JC, Yildiz F, Cegelski L | Biochimica et biophysica acta | 24911407 | Biochim Biophys Acta | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24911407 |
Frequency-selective REDOR and spin-diffusion relays in uniformly labeled whole cells. | Rice DM, Romaniuk JA, Cegelski L | Solid state nuclear magnetic resonance | 26493462 | Solid State Nucl Magn Reson | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26493462 |
Molecular determinants of mechanical properties of V. cholerae biofilms at the air-liquid interface. | Hollenbeck EC, Fong JC, Lim JY, Yildiz FH, Fuller GG, Cegelski L | Biophysical journal | 25418293 | Biophys J | 2014 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/25418293 |
Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. | Tucker BA, Anfinson KR, Mullins RF, Stone EM, Young MJ | Stem cells translational medicine | 23283489 | Stem Cells Transl Med | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23283489 |
Intravesical and alternative bladder-preservation therapies in the management of non-muscle-invasive bladder cancer unresponsive to bacillus Calmette-Guérin. | Steinberg RL, Thomas LJ, Nepple KG | Urologic oncology | 26777259 | Urol Oncol | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26777259 |
SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. | Ozden O, Park SH, Wagner BA, Song HY, Zhu Y, Vassilopoulos A, Jung B, Buettner GR, Gius D | Free radical biology & medicine | 25152236 | Free Radic Biol Med | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25152236 |
Is age-related macular degeneration a microvascular disease? | Mullins RF, Khanna A, Schoo DP, Tucker BA, Sohn EH, Drack AV, Stone EM | Advances in experimental medicine and biology | 24664709 | Adv Exp Med Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24664709 |
CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype. | Burnight ER, Wiley LA, Drack AV, Braun TA, Anfinson KR, Kaalberg EE, Halder JA, Affatigato LM, Mullins RF, Stone EM, Tucker BA | Gene therapy | 24807808 | Gene Ther | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24807808 |
Stem cells for investigation and treatment of inherited retinal disease. | Tucker BA, Mullins RF, Stone EM | Human molecular genetics | 24647603 | Hum Mol Genet | 2014 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/24647603 |
Prognostic factors for survival in patients with high-grade osteosarcoma using the Surveillance, Epidemiology, and End Results (SEER) Program database. | Duchman KR, Gao Y, Miller BJ | Cancer epidemiology | 26002013 | Cancer Epidemiol | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26002013 |
Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration. | Songstad AE, Wiley LA, Duong K, Kaalberg E, Flamme-Wiese MJ, Cranston CM, Riker MJ, Levasseur D, Stone EM, Mullins RF, Tucker BA | Investigative ophthalmology & visual science | 26720480 | Invest Ophthalmol Vis Sci | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26720480 |
Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease. | Giacalone JC, Wiley LA, Burnight ER, Songstad AE, Mullins RF, Stone EM, Tucker BA | Stem cells translational medicine | 26683869 | Stem Cells Transl Med | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26683869 |
Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds. | Worthington KS, Wiley LA, Guymon CA, Salem AK, Tucker BA | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics | 26692377 | J Ocul Pharmacol Ther | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26692377 |
Molecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration. | Zeng S, Whitmore SS, Sohn EH, Riker MJ, Wiley LA, Scheetz TE, Stone EM, Tucker BA, Mullins RF | The Journal of pathology | 26564985 | J Pathol | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26564985 |
Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. | Tucker BA, Mullins RF, Streb LM, Anfinson K, Eyestone ME, Kaalberg E, Riker MJ, Drack AV, Braun TA, Stone EM | eLife | 23991284 | Elife | 2013 Aug 27 | https://www.ncbi.nlm.nih.gov/pubmed/23991284 |
Vending Assessment and Program Implementation in Four Iowa Worksites. | Lillehoj CJ, Nothwehr F, Shipley K, Voss C | Health promotion practice | 26220278 | Health Promot Pract | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26220278 |
Controlled drug delivery from 3D printed two-photon polymerized poly(ethylene glycol) dimethacrylate devices. | Do AV, Worthington KS, Tucker BA, Salem AK | International journal of pharmaceutics | 30268853 | Int J Pharm | 2018 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/30268853 |
Gene therapy using stem cells. | Burnight ER, Wiley LA, Mullins RF, Stone EM, Tucker BA | Cold Spring Harbor perspectives in medicine | 25395375 | Cold Spring Harb Perspect Med | 2014 Nov 13 | https://www.ncbi.nlm.nih.gov/pubmed/25395375 |
Allogenic iPSC-derived RPE cell transplants induce immune response in pigs: a pilot study. | Sohn EH, Jiao C, Kaalberg E, Cranston C, Mullins RF, Stone EM, Tucker BA | Scientific reports | 26138532 | Sci Rep | 2015 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/26138532 |
Perception of patient appearance following various methods of reconstruction after orbital exenteration. | Kuiper JJ, Zimmerman MB, Pagedar NA, Carter KD, Allen RC, Shriver EM | Orbit (Amsterdam, Netherlands) | 27341072 | Orbit | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27341072 |
Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy. | Whitmore SS, Sohn EH, Chirco KR, Drack AV, Stone EM, Tucker BA, Mullins RF | Progress in retinal and eye research | 25486088 | Prog Retin Eye Res | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25486088 |
Mechanical properties of murine and porcine ocular tissues in compression. | Worthington KS, Wiley LA, Bartlett AM, Stone EM, Mullins RF, Salem AK, Guymon CA, Tucker BA | Experimental eye research | 24613781 | Exp Eye Res | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24613781 |
ABCB5 is a limbal stem cell gene required for corneal development and repair. | Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY | Nature | 25030174 | Nature | 2014 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/25030174 |
Sources of bias in peoples' social-comparative estimates of food consumption. | Scherer AM, Bruchmann K, Windschitl PD, Rose JP, Smith AR, Koestner B, Snetselaar L, Suls J | Journal of experimental psychology. Applied | 27054551 | J Exp Psychol Appl | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27054551 |
Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases. | Wiley LA, Burnight ER, Songstad AE, Drack AV, Mullins RF, Stone EM, Tucker BA | Progress in retinal and eye research | 25448922 | Prog Retin Eye Res | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25448922 |
Stem cells as tools for studying the genetics of inherited retinal degenerations. | Wiley LA, Burnight ER, Mullins RF, Stone EM, Tucker BA | Cold Spring Harbor perspectives in medicine | 25502747 | Cold Spring Harb Perspect Med | 2014 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/25502747 |
Natural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy. | Boye SE, Huang WC, Roman AJ, Sumaroka A, Boye SL, Ryals RC, Olivares MB, Ruan Q, Tucker BA, Stone EM, Swaroop A, Cideciyan AV, Hauswirth WW, Jacobson SG | PloS one | 24671090 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24671090 |
The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning. | Mullins RF, Schoo DP, Sohn EH, Flamme-Wiese MJ, Workamelahu G, Johnston RM, Wang K, Tucker BA, Stone EM | The American journal of pathology | 25204844 | Am J Pathol | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25204844 |
Structural and biochemical analyses of choroidal thickness in human donor eyes. | Sohn EH, Khanna A, Tucker BA, Abràmoff MD, Stone EM, Mullins RF | Investigative ophthalmology & visual science | 24519422 | Invest Ophthalmol Vis Sci | 2014 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/24519422 |
Use of the Teres Major Muscle in Chimeric Subscapular System Free Flaps for Head and Neck Reconstruction. | Tomlinson AR, Jameson MJ, Pagedar NA, Schoeff SS, Shearer AE, Boyd NH | JAMA otolaryngology-- head & neck surgery | 26312435 | JAMA Otolaryngol Head Neck Surg | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26312435 |
Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis. | DeLuca AP, Whitmore SS, Barnes J, Sharma TP, Westfall TA, Scott CA, Weed MC, Wiley JS, Wiley LA, Johnston RM, Schnieders MJ, Lentz SR, Tucker BA, Mullins RF, Scheetz TE, Stone EM, Slusarski DC | Human molecular genetics | 26494905 | Hum Mol Genet | 2016 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/26494905 |
Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease. | Braun TA, Mullins RF, Wagner AH, Andorf JL, Johnston RM, Bakall BB, Deluca AP, Fishman GA, Lam BL, Weleber RG, Cideciyan AV, Jacobson SG, Sheffield VC, Tucker BA, Stone EM | Human molecular genetics | 23918662 | Hum Mol Genet | 2013 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/23918662 |
Two-Photon Polymerization as a Tool for Studying 3D Printed Topography-Induced Stem Cell Fate. | Worthington KS, Do AV, Smith R, Tucker BA, Salem AK | Macromolecular bioscience | 30430755 | Macromol Biosci | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30430755 |
Weight loss after head and neck cancer: A dynamic relationship with depressive symptoms. | Van Liew JR, Brock RL, Christensen AJ, Karnell LH, Pagedar NA, Funk GF | Head & neck | 27704695 | Head Neck | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/27704695 |
A Method for Sectioning and Immunohistochemical Analysis of Stem Cell-Derived 3-D Organoids. | Wiley LA, Beebe DC, Mullins RF, Stone EM, Tucker BA | Current protocols in stem cell biology | 27171793 | Curr Protoc Stem Cell Biol | 2016 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/27171793 |
Photoreceptor cells with profound structural deficits can support useful vision in mice. | Thompson S, Blodi FR, Lee S, Welder CR, Mullins RF, Tucker BA, Stasheff SF, Stone EM | Investigative ophthalmology & visual science | 24569582 | Invest Ophthalmol Vis Sci | 2014 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/24569582 |
Low-oxygen culture conditions extend the multipotent properties of human retinal progenitor cells. | Baranov PY, Tucker BA, Young MJ | Tissue engineering. Part A | 24320879 | Tissue Eng Part A | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24320879 |
Loss of CD34 expression in aging human choriocapillaris endothelial cells. | Sohn EH, Flamme-Wiese MJ, Whitmore SS, Wang K, Tucker BA, Mullins RF | PloS one | 24466138 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24466138 |
Risk of recurrent preterm birth among women according to change in partner. | Baer RJ, Yang J, Chambers CD, Ryckman KK, Saftlas AF, Berghella V, Schetter CD, Shaw GM, Stevenson DK, Jelliffe-Pawlowski LL | Journal of perinatal medicine | 27718495 | J Perinat Med | 2017 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/27718495 |
Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma. | Tucker BA, Solivan-Timpe F, Roos BR, Anfinson KR, Robin AL, Wiley LA, Mullins RF, Fingert JH | Journal of stem cell research & therapy | 24883232 | J Stem Cell Res Ther | 2014 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/24883232 |
Treatment and Survival Trends in Glottic Carcinoma in Situ and Stage I Cancer From 1988 to 2012. | Khaja SF, Hoffman HT, Pagedar NA | The Annals of otology, rhinology, and laryngology | 26481178 | Ann Otol Rhinol Laryngol | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26481178 |
cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. | Wiley LA, Burnight ER, DeLuca AP, Anfinson KR, Cranston CM, Kaalberg EE, Penticoff JA, Affatigato LM, Mullins RF, Stone EM, Tucker BA | Scientific reports | 27471043 | Sci Rep | 2016 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/27471043 |
Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa. | Tucker BA, Scheetz TE, Mullins RF, DeLuca AP, Hoffmann JM, Johnston RM, Jacobson SG, Sheffield VC, Stone EM | Proceedings of the National Academy of Sciences of the United States of America | 21825139 | Proc Natl Acad Sci U S A | 2011 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/21825139 |
Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis. | Drivas TG, Wojno AP, Tucker BA, Stone EM, Bennett J | Science translational medicine | 26062849 | Sci Transl Med | 2015 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/26062849 |
Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq. | Whitmore SS, Wagner AH, DeLuca AP, Drack AV, Stone EM, Tucker BA, Zeng S, Braun TA, Mullins RF, Scheetz TE | Experimental eye research | 25446321 | Exp Eye Res | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25446321 |
Using patient-specific induced pluripotent stem cells to interrogate the pathogenicity of a novel retinal pigment epithelium-specific 65 kDa cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial. | Tucker BA, Cranston CM, Anfinson KA, Shrestha S, Streb LM, Leon A, Mullins RF, Stone EM | Translational research : the journal of laboratory and clinical medicine | 26364624 | Transl Res | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26364624 |
Prevascularized silicon membranes for the enhancement of transport to implanted medical devices. | Worthington KS, Wiley LA, Mullins RF, Tucker BA, Nuxoll E | Journal of biomedical materials research. Part B, Applied biomaterials | 26316050 | J Biomed Mater Res B Appl Biomater | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26316050 |
Influence of a loop electrosurgical excision procedure (LEEP) on levels of cytokines in cervical secretions. | Saftlas AF, Spracklen CN, Ryckman KK, Stockdale CK, Penrose K, Ault K, Rubenstein LM, Pinto LA | Journal of reproductive immunology | 25721621 | J Reprod Immunol | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25721621 |
Velocity profiles in pores with undulating opening diameter and their importance for resistive-pulse experiments. | Innes LM, Chen CH, Schiel M, Pevarnik M, Haurais F, Toimil-Molares ME, Vlassiouk I, Theogarajan L, Siwy ZS | Analytical chemistry | 25245282 | Anal Chem | 2014 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/25245282 |
Tailored Polymeric Membranes for Mycobacterium Smegmatis Porin A (MspA) Based Biosensors. | Morton D, Mortezaei S, Yemenicioglu S, Isaacman MJ, Nova IC, Gundlach JH, Theogarajan L | Journal of materials chemistry. B | 26413301 | J Mater Chem B | 2015 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/26413301 |
Solid-state nanopore based biomimetic voltage gated ion channels. | Pevarnik M, Cui W, Yemenicioglu S, Rofeh J, Theogarajan L | Bioinspiration & biomimetics | 28726670 | Bioinspir Biomim | 2017 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/28726670 |
Wafer Scale Integration of CMOS Chips for Biomedical Applications via Self-Aligned Masking. | Uddin A, Milaninia K, Chen CH, Theogarajan L | IEEE transactions on components, packaging, and manufacturing technology | 22400126 | IEEE Trans Compon Packaging Manuf Technol | 2011 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/22400126 |
A CMOS enhanced solid-state nanopore based single molecule detection platform. | Chen C, Yemenicioglu S, Uddin A, Corgliano E, Theogarajan L | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 24109650 | Annu Int Conf IEEE Eng Med Biol Soc | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24109650 |
Clickable Amphiphilic Triblock Copolymers. | Isaacman MJ, Barron KA, Theogarajan LS | Journal of polymer science. Part A, Polymer chemistry | 23100856 | J Polym Sci A Polym Chem | 2012 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/23100856 |
Rapid Metal -free Macromolecular Coupling via in situ Nitrile Oxide-Activated Alkene Cycloaddition. | Isaacman MJ, Cui W, Theogarajan LS | Journal of polymer science. Part A, Polymer chemistry | 26811566 | J Polym Sci A Polym Chem | 2014 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/26811566 |
Integration of solid-state nanopores in a 0.5 μm CMOS foundry process. | Uddin A, Yemenicioglu S, Chen CH, Corigliano E, Milaninia K, Theogarajan L | Nanotechnology | 23519330 | Nanotechnology | 2013 Apr 19 | https://www.ncbi.nlm.nih.gov/pubmed/23519330 |
Stealth polymeric vesicles via metal-free click coupling. | Isaacman MJ, Corigliano EM, Theogarajan LS | Biomacromolecules | 23952743 | Biomacromolecules | 2013 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/23952743 |
Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease. | Yoruk B, Gillers BS, Chi NC, Scott IC | Developmental biology | 22182521 | Dev Biol | 2012 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/22182521 |
Zebrafish cardiac injury and regeneration models: a noninvasive and invasive in vivo model of cardiac regeneration. | Dickover MS, Zhang R, Han P, Chi NC | Methods in molecular biology (Clifton, N.J.) | 24029953 | Methods Mol Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24029953 |
Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure. | Hashem SI, Perry CN, Bauer M, Han S, Clegg SD, Ouyang K, Deacon DC, Spinharney M, Panopoulos AD, Izpisua Belmonte JC, Frazer KA, Chen J, Gong Q, Zhou Z, Chi NC, Adler ED | Stem cells (Dayton, Ohio) | 25826782 | Stem Cells | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25826782 |
In vivo cardiac reprogramming contributes to zebrafish heart regeneration. | Zhang R, Han P, Yang H, Ouyang K, Lee D, Lin YF, Ocorr K, Kang G, Chen J, Stainier DY, Yelon D, Chi NC | Nature | 23783515 | Nature | 2013 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/23783515 |
The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. | Dickover M, Hegarty JM, Ly K, Lopez D, Yang H, Zhang R, Tedeschi N, Hsiai TK, Chi NC | Developmental biology | 24607366 | Dev Biol | 2014 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/24607366 |
Zebrafish models in cardiac development and congenital heart birth defects. | Tu S, Chi NC | Differentiation; research in biological diversity | 22704690 | Differentiation | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22704690 |
Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function. | Palencia-Desai S, Kohli V, Kang J, Chi NC, Black BL, Sumanas S | Development (Cambridge, England) | 21989916 | Development | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21989916 |
Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development. | Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC | Developmental biology | 26004360 | Dev Biol | 2015 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/26004360 |
Epigenomic analysis of multilineage differentiation of human embryonic stem cells. | Xie W, Schultz MD, Lister R, Hou Z, Rajagopal N, Ray P, Whitaker JW, Tian S, Hawkins RD, Leung D, Yang H, Wang T, Lee AY, Swanson SA, Zhang J, Zhu Y, Kim A, Nery JR, Urich MA, Kuan S, Yen CA, Klugman S, Yu P, Suknuntha K, Propson NE, Chen H, Edsall LE, Wagner U, Li Y, Ye Z, Kulkarni A, Xuan Z, Chung WY, Chi NC, Antosiewicz-Bourget JE, Slukvin I, Stewart R, Zhang MQ, Wang W, Thomson JA, Ecker JR, Ren B | Cell | 23664764 | Cell | 2013 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/23664764 |
Wearable multi-channel microelectrode membranes for elucidating electrophysiological phenotypes of injured myocardium. | Cao H, Yu F, Zhao Y, Zhang X, Tai J, Lee J, Darehzereshki A, Bersohn M, Lien CL, Chi NC, Tai YC, Hsiai TK | Integrative biology : quantitative biosciences from nano to macro | 24945366 | Integr Biol (Camb) | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24945366 |
Myocardial plasticity: cardiac development, regeneration and disease. | Bloomekatz J, Galvez-Santisteban M, Chi NC | Current opinion in genetics & development | 27498024 | Curr Opin Genet Dev | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27498024 |
Disease Burden and Symptom Structure of Autism in Neurofibromatosis Type 1: A Study of the International NF1-ASD Consortium Team (INFACT). | Morris SM, Acosta MT, Garg S, Green J, Huson S, Legius E, North KN, Payne JM, Plasschaert E, Frazier TW, Weiss LA, Zhang Y, Gutmann DH, Constantino JN | JAMA psychiatry | 27760236 | JAMA Psychiatry | 2016 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/27760236 |
Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. | Deshpande A, Yadav S, Dao DQ, Wu ZY, Hokanson KC, Cahill MK, Wiita AP, Jan YN, Ullian EM, Weiss LA | Cell reports | 29212016 | Cell Rep | 2017 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/29212016 |
Age and ASD symptoms in Costello syndrome. | Young O, Perati S, Weiss LA, Rauen KA | American journal of medical genetics. Part A | 29575620 | Am J Med Genet A | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29575620 |
Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. | Josowitz R, Mulero-Navarro S, Rodriguez NA, Falce C, Cohen N, Ullian EM, Weiss LA, Rauen KA, Sobie EA, Gelb BD | Stem cell reports | 27569062 | Stem Cell Reports | 2016 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/27569062 |
Craniofacial and dental development in cardio-facio-cutaneous syndrome: the importance of Ras signaling homeostasis. | Goodwin AF, Oberoi S, Landan M, Charles C, Groth J, Martinez A, Fairley C, Weiss LA, Tidyman WE, Klein OD, Rauen KA | Clinical genetics | 22946697 | Clin Genet | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/22946697 |
Dysregulation of astrocyte extracellular signaling in Costello syndrome. | Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney GE, Rauen KA, Weiss LA, Rowitch DH, Ullian EM | Science translational medicine | 25947161 | Sci Transl Med | 2015 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/25947161 |
Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. | Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM | The Journal of neuroscience : the official journal of the Society for Neuroscience | 26740656 | J Neurosci | 2016 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/26740656 |
Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders. | Mitra I, Lavillaureix A, Yeh E, Traglia M, Tsang K, Bearden CE, Rauen KA, Weiss LA | PLoS genetics | 28076348 | PLoS Genet | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28076348 |
Autism traits in the RASopathies. | Adviento B, Corbin IL, Widjaja F, Desachy G, Enrique N, Rosser T, Risi S, Marco EJ, Hendren RL, Bearden CE, Rauen KA, Weiss LA | Journal of medical genetics | 24101678 | J Med Genet | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24101678 |
Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment. | Yeh E, Dao DQ, Wu ZY, Kandalam SM, Camacho FM, Tom C, Zhang W, Krencik R, Rauen KA, Ullian EM, Weiss LA | Molecular psychiatry | 29158583 | Mol Psychiatry | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29158583 |
RASopathies are associated with a distinct personality profile. | Bizaoui V, Gage J, Brar R, Rauen KA, Weiss LA | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics | 29659143 | Am J Med Genet B Neuropsychiatr Genet | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29659143 |
Global turnover of histone post-translational modifications and variants in human cells. | Zee BM, Levin RS, DiMaggio PA, Garcia BA | Epigenetics & chromatin | 21134274 | Epigenetics Chromatin | 2010 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/21134274 |
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. | Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K | Nature cell biology | 23748610 | Nat Cell Biol | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23748610 |
A Novel Quantitative Mass Spectrometry Platform for Determining Protein O-GlcNAcylation Dynamics. | Wang X, Yuan ZF, Fan J, Karch KR, Ball LE, Denu JM, Garcia BA | Molecular & cellular proteomics : MCP | 27114449 | Mol Cell Proteomics | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27114449 |
Quantitative proteomic analysis of histone modifications. | Huang H, Lin S, Garcia BA, Zhao Y | Chemical reviews | 25688442 | Chem Rev | 2015 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/25688442 |
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. | Kanno T, Kanno Y, LeRoy G, Campos E, Sun HW, Brooks SR, Vahedi G, Heightman TD, Garcia BA, Reinberg D, Siebenlist U, O'Shea JJ, Ozato K | Nature structural & molecular biology | 25383670 | Nat Struct Mol Biol | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25383670 |
In vivo proximity labeling for the detection of protein-protein and protein-RNA interactions. | Beck DB, Narendra V, Drury WJ 3rd, Casey R, Jansen PW, Yuan ZF, Garcia BA, Vermeulen M, Bonasio R | Journal of proteome research | 25311790 | J Proteome Res | 2014 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/25311790 |
Post-Translational Modification Profiling--a High-Content Assay for Identifying Protein Modifications in Mammalian Cellular Systems. | Merbl Y, Kirschner MW | Current protocols in protein science | 25081743 | Curr Protoc Protein Sci | 2014 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/25081743 |
A proteomic glimpse into the initial global epigenetic changes during HIV infection. | Britton LM, Sova P, Belisle S, Liu S, Chan EY, Katze MG, Garcia BA | Proteomics | 25116026 | Proteomics | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25116026 |
PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism. | Jain SU, Do TJ, Lund PJ, Rashoff AQ, Diehl KL, Cieslik M, Bajic A, Juretic N, Deshmukh S, Venneti S, Muir TW, Garcia BA, Jabado N, Lewis PW | Nature communications | 31086175 | Nat Commun | 2019 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/31086175 |
LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. | Nguyen H, Allali-Hassani A, Antonysamy S, Chang S, Chen LH, Curtis C, Emtage S, Fan L, Gheyi T, Li F, Liu S, Martin JR, Mendel D, Olsen JB, Pelletier L, Shatseva T, Wu S, Zhang FF, Arrowsmith CH, Brown PJ, Campbell RM, Garcia BA, Barsyte-Lovejoy D, Mader M, Vedadi M | The Journal of biological chemistry | 25825497 | J Biol Chem | 2015 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/25825497 |
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. | Chicas A, Kapoor A, Wang X, Aksoy O, Evertts AG, Zhang MQ, Garcia BA, Bernstein E, Lowe SW | Proceedings of the National Academy of Sciences of the United States of America | 22615382 | Proc Natl Acad Sci U S A | 2012 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/22615382 |
Comprehending dynamic protein methylation with mass spectrometry. | Afjehi-Sadat L, Garcia BA | Current opinion in chemical biology | 23333572 | Curr Opin Chem Biol | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23333572 |
Asymmetrically modified nucleosomes. | Voigt P, LeRoy G, Drury WJ 3rd, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D | Cell | 23021224 | Cell | 2012 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/23021224 |
Breaking the histone code with quantitative mass spectrometry. | Britton LM, Gonzales-Cope M, Zee BM, Garcia BA | Expert review of proteomics | 21999833 | Expert Rev Proteomics | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21999833 |
Proteomic interrogation of human chromatin. | Torrente MP, Zee BM, Young NL, Baliban RC, LeRoy G, Floudas CA, Hake SB, Garcia BA | PloS one | 21935452 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/21935452 |
Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression. | Peixoto LL, Wimmer ME, Poplawski SG, Tudor JC, Kenworthy CA, Liu S, Mizuno K, Garcia BA, Zhang NR, Giese K, Abel T | BMC genomics | 26040834 | BMC Genomics | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26040834 |
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. | Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, Hother C, Liu S, Cao XJ, Tam W, Shaknovich R, Garcia BA, Gascoyne RD, Ge K, Shilatifard A, Elemento O, Nussenzweig A, Melnick AM, Wendel HG | Nature medicine | 26366710 | Nat Med | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26366710 |
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression. | Jain SU, Khazaei S, Marchione DM, Lundgren SM, Wang X, Weinberg DN, Deshmukh S, Juretic N, Lu C, Allis CD, Garcia BA, Jabado N, Lewis PW | Proceedings of the National Academy of Sciences of the United States of America | 33067396 | Proc Natl Acad Sci U S A | 2020 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/33067396 |
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. | Vedadi M, Barsyte-Lovejoy D, Liu F, Rival-Gervier S, Allali-Hassani A, Labrie V, Wigle TJ, Dimaggio PA, Wasney GA, Siarheyeva A, Dong A, Tempel W, Wang SC, Chen X, Chau I, Mangano TJ, Huang XP, Simpson CD, Pattenden SG, Norris JL, Kireev DB, Tripathy A, Edwards A, Roth BL, Janzen WP, Garcia BA, Petronis A, Ellis J, Brown PJ, Frye SV, Arrowsmith CH, Jin J | Nature chemical biology | 21743462 | Nat Chem Biol | 2011 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/21743462 |
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. | Ratnakumar K, Duarte LF, LeRoy G, Hasson D, Smeets D, Vardabasso C, Bönisch C, Zeng T, Xiang B, Zhang DY, Li H, Wang X, Hake SB, Schermelleh L, Garcia BA, Bernstein E | Genes & development | 22391447 | Genes Dev | 2012 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/22391447 |
The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. | Wu L, Zee BM, Wang Y, Garcia BA, Dou Y | Molecular cell | 21726816 | Mol Cell | 2011 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/21726816 |
High resolution is not a strict requirement for characterization and quantification of histone post-translational modifications. | Karch KR, Zee BM, Garcia BA | Journal of proteome research | 25325711 | J Proteome Res | 2014 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/25325711 |
Low Resolution Data-Independent Acquisition in an LTQ-Orbitrap Allows for Simplified and Fully Untargeted Analysis of Histone Modifications. | Sidoli S, Simithy J, Karch KR, Kulej K, Garcia BA | Analytical chemistry | 26505526 | Anal Chem | 2015 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/26505526 |
Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations. | Önder Ö, Sidoli S, Carroll M, Garcia BA | Expert review of proteomics | 26400466 | Expert Rev Proteomics | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26400466 |
Heavy methyl-SILAC labeling coupled with liquid chromatography and high-resolution mass spectrometry to study the dynamics of site-specific histone methylation. | Cao XJ, Zee BM, Garcia BA | Methods in molecular biology (Clifton, N.J.) | 23436372 | Methods Mol Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23436372 |
Large-scale global identification of protein lysine methylation in vivo. | Cao XJ, Arnaudo AM, Garcia BA | Epigenetics | 23644510 | Epigenetics | 2013 May | https://www.ncbi.nlm.nih.gov/pubmed/23644510 |
Validation of protein acetylation by mass spectrometry. | Zee BM, Garcia BA | Methods in molecular biology (Clifton, N.J.) | 23381849 | Methods Mol Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23381849 |
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. | Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, Gozani O | Nature | 24847881 | Nature | 2014 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/24847881 |
Middle-Down and Top-Down Mass Spectrometric Analysis of Co-occurring Histone Modifications. | Molden RC, Garcia BA | Current protocols in protein science | 25081742 | Curr Protoc Protein Sci | 2014 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/25081742 |
Evaluation of proteomic search engines for the analysis of histone modifications. | Yuan ZF, Lin S, Molden RC, Garcia BA | Journal of proteome research | 25167464 | J Proteome Res | 2014 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/25167464 |
Characterization of BRD4 during mammalian postmeiotic sperm development. | Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL | Molecular and cellular biology | 25691659 | Mol Cell Biol | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25691659 |
Mass spectrometric analysis of histone proteoforms. | Yuan ZF, Arnaudo AM, Garcia BA | Annual review of analytical chemistry (Palo Alto, Calif.) | 24896311 | Annu Rev Anal Chem (Palo Alto Calif) | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24896311 |
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. | Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF | Nature | 22722849 | Nature | 2012 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/22722849 |
Global secretome analysis identifies novel mediators of bone metastasis. | Blanco MA, LeRoy G, Khan Z, Alečković M, Zee BM, Garcia BA, Kang Y | Cell research | 22688892 | Cell Res | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22688892 |
Discovery of lysine post-translational modifications through mass spectrometric detection. | Zee BM, Garcia BA | Essays in biochemistry | 22708569 | Essays Biochem | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22708569 |
EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra. | Yuan ZF, Lin S, Molden RC, Cao XJ, Bhanu NV, Wang X, Sidoli S, Liu S, Garcia BA | Molecular & cellular proteomics : MCP | 25805797 | Mol Cell Proteomics | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25805797 |
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. | Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW | Science (New York, N.Y.) | 27174990 | Science | 2016 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/27174990 |
Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis. | Sidoli S, Yuan ZF, Lin S, Karch K, Wang X, Bhanu N, Arnaudo AM, Britton LM, Cao XJ, Gonzales-Cope M, Han Y, Liu S, Molden RC, Wein S, Afjehi-Sadat L, Garcia BA | Proteomics | 25641854 | Proteomics | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25641854 |
Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. | Kang S, Tsai LT, Zhou Y, Evertts A, Xu S, Griffin MJ, Issner R, Whitton HJ, Garcia BA, Epstein CB, Mikkelsen TS, Rosen ED | Nature cell biology | 25503565 | Nat Cell Biol | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25503565 |
Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry. | Lin S, Wein S, Gonzales-Cope M, Otte GL, Yuan ZF, Afjehi-Sadat L, Maile T, Berger SL, Rush J, Lill JR, Arnott D, Garcia BA | Molecular & cellular proteomics : MCP | 25000943 | Mol Cell Proteomics | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25000943 |
Revealing histone variant induced changes via quantitative proteomics. | Arnaudo AM, Molden RC, Garcia BA | Critical reviews in biochemistry and molecular biology | 21526979 | Crit Rev Biochem Mol Biol | 2011 Aug | https://www.ncbi.nlm.nih.gov/pubmed/21526979 |
Examining histone posttranslational modification patterns by high-resolution mass spectrometry. | Lin S, Garcia BA | Methods in enzymology | 22910200 | Methods Enzymol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22910200 |
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. | Binda O, Sevilla A, LeRoy G, Lemischka IR, Garcia BA, Richard S | Epigenetics | 23324626 | Epigenetics | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23324626 |
Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. | Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton LM, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI | Nature structural & molecular biology | 23295261 | Nat Struct Mol Biol | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23295261 |
Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells. | Gonzales-Cope M, Sidoli S, Bhanu NV, Won KJ, Garcia BA | BMC genomics | 26847871 | BMC Genomics | 2016 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/26847871 |
Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. | Van Aller GS, Reynoird N, Barbash O, Huddleston M, Liu S, Zmoos AF, McDevitt P, Sinnamon R, Le B, Mas G, Annan R, Sage J, Garcia BA, Tummino PJ, Gozani O, Kruger RG | Epigenetics | 22419068 | Epigenetics | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22419068 |
Combining genomic and proteomic approaches for epigenetics research. | Han Y, Garcia BA | Epigenomics | 23895656 | Epigenomics | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23895656 |
Proteomic characterization of novel histone post-translational modifications. | Arnaudo AM, Garcia BA | Epigenetics & chromatin | 23916056 | Epigenetics Chromatin | 2013 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/23916056 |
H4K20 methylation regulates quiescence and chromatin compaction. | Evertts AG, Manning AL, Wang X, Dyson NJ, Garcia BA, Coller HA | Molecular biology of the cell | 23924899 | Mol Biol Cell | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23924899 |
Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies. | Rothbart SB, Lin S, Britton LM, Krajewski K, Keogh MC, Garcia BA, Strahl BD | Scientific reports | 22761995 | Sci Rep | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22761995 |
Origins and formation of histone methylation across the human cell cycle. | Zee BM, Britton LM, Wolle D, Haberman DM, Garcia BA | Molecular and cellular biology | 22547680 | Mol Cell Biol | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22547680 |
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. | Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E | Nature communications | 23463008 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23463008 |
An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions. | Sevilla A, Papatsenko D, Mazloom AR, Xu H, Vasileva A, Unwin RD, LeRoy G, Chen EY, Garrett-Bakelman FE, Lee DF, Trinite B, Webb RL, Wang Z, Su J, Gingold J, Melnick A, Garcia BA, Whetton AD, MacArthur BD, Ma'ayan A, Lemischka IR | Frontiers in cell and developmental biology | 33816475 | Front Cell Dev Biol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33816475 |
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. | Lewis PW, Müller MM, Koletsky MS, Cordero F, Lin S, Banaszynski LA, Garcia BA, Muir TW, Becher OJ, Allis CD | Science (New York, N.Y.) | 23539183 | Science | 2013 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/23539183 |
Quantitative dynamics of the link between cellular metabolism and histone acetylation. | Evertts AG, Zee BM, Dimaggio PA, Gonzales-Cope M, Coller HA, Garcia BA | The Journal of biological chemistry | 23482559 | J Biol Chem | 2013 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/23482559 |
Initial characterization of histone H3 serine 10 O-acetylation. | Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA | Epigenetics | 23949383 | Epigenetics | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23949383 |
Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. | Wu Y, DiMaggio PA Jr, Perlman DH, Zakian VA, Garcia BA | Journal of proteome research | 23181431 | J Proteome Res | 2013 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/23181431 |
Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins. | LeRoy G, Chepelev I, DiMaggio PA, Blanco MA, Zee BM, Zhao K, Garcia BA | Genome biology | 22897906 | Genome Biol | 2012 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/22897906 |
De novo peptide design and experimental validation of histone methyltransferase inhibitors. | Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, Giannis A, Trojer P, Garcia BA, Floudas CA | PloS one | 24587223 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24587223 |
Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection. | O'Connor CM, DiMaggio PA Jr, Shenk T, Garcia BA | Molecular & cellular proteomics : MCP | 24987098 | Mol Cell Proteomics | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/24987098 |
Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. | Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, Won KJ, Chodosh LA, Garcia BA, Stanger BZ, Feldman MD, Blair IA, Wellen KE | Cell metabolism | 24998913 | Cell Metab | 2014 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/24998913 |
H3R42me2a is a histone modification with positive transcriptional effects. | Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD | Proceedings of the National Academy of Sciences of the United States of America | 23980157 | Proc Natl Acad Sci U S A | 2013 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/23980157 |
Neutron-encoded mass signatures for quantitative top-down proteomics. | Rhoads TW, Rose CM, Bailey DJ, Riley NM, Molden RC, Nestler AJ, Merrill AE, Smith LM, Hebert AS, Westphall MS, Pagliarini DJ, Garcia BA, Coon JJ | Analytical chemistry | 24475910 | Anal Chem | 2014 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/24475910 |
Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses. | Green EM, Mas G, Young NL, Garcia BA, Gozani O | Nature structural & molecular biology | 22343720 | Nat Struct Mol Biol | 2012 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/22343720 |
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. | Kuo AJ, Cheung P, Chen K, Zee BM, Kioi M, Lauring J, Xi Y, Park BH, Shi X, Garcia BA, Li W, Gozani O | Molecular cell | 22099308 | Mol Cell | 2011 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/22099308 |
Complete Workflow for Analysis of Histone Post-translational Modifications Using Bottom-up Mass Spectrometry: From Histone Extraction to Data Analysis. | Sidoli S, Bhanu NV, Karch KR, Wang X, Garcia BA | Journal of visualized experiments : JoVE | 27286567 | J Vis Exp | 2016 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/27286567 |
SnapShot: histone modifications. | Huang H, Sabari BR, Garcia BA, Allis CD, Zhao Y | Cell | 25303536 | Cell | 2014 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/25303536 |
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia. | Xu B, On DM, Ma A, Parton T, Konze KD, Pattenden SG, Allison DF, Cai L, Rockowitz S, Liu S, Liu Y, Li F, Vedadi M, Frye SV, Garcia BA, Zheng D, Jin J, Wang GG | Blood | 25395428 | Blood | 2015 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/25395428 |
Quantitative proteomic approaches to studying histone modifications. | Zee BM, Young NL, Garcia BA | Current chemical genomics | 21966350 | Curr Chem Genomics | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/21966350 |
Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications. | Molden RC, Bhanu NV, LeRoy G, Arnaudo AM, Garcia BA | Epigenetics & chromatin | 25922622 | Epigenetics Chromatin | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25922622 |
Bottom-up and middle-down proteomics have comparable accuracies in defining histone post-translational modification relative abundance and stoichiometry. | Sidoli S, Lin S, Karch KR, Garcia BA | Analytical chemistry | 25719549 | Anal Chem | 2015 Mar 17 | https://www.ncbi.nlm.nih.gov/pubmed/25719549 |
Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications. | Vasudevan D, Hickok JR, Bovee RC, Pham V, Mantell LL, Bahroos N, Kanabar P, Cao XJ, Maienschein-Cline M, Garcia BA, Thomas DD | Cancer research | 26542213 | Cancer Res | 2015 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/26542213 |
Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2. | Garrigues JM, Sidoli S, Garcia BA, Strome S | Genome research | 25467431 | Genome Res | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25467431 |
Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain. | Menni C, Jackson MA, Pallister T, Steves CJ, Spector TD, Valdes AM | International journal of obesity (2005) | 28286339 | Int J Obes (Lond) | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28286339 |
Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice. | Ji Y, Sun S, Goodrich JK, Kim H, Poole AC, Duhamel GE, Ley RE, Qi L | Cell reports | 24953658 | Cell Rep | 2014 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/24953658 |
Signatures of early frailty in the gut microbiota. | Jackson MA, Jeffery IB, Beaumont M, Bell JT, Clark AG, Ley RE, O'Toole PW, Spector TD, Steves CJ | Genome medicine | 26822992 | Genome Med | 2016 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/26822992 |
Host remodeling of the gut microbiome and metabolic changes during pregnancy. | Koren O, Goodrich JK, Cullender TC, Spor A, Laitinen K, Bäckhed HK, Gonzalez A, Werner JJ, Angenent LT, Knight R, Bäckhed F, Isolauri E, Salminen S, Ley RE | Cell | 22863002 | Cell | 2012 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/22863002 |
Innate and adaptive immunity interact to quench microbiome flagellar motility in the gut. | Cullender TC, Chassaing B, Janzon A, Kumar K, Muller CE, Werner JJ, Angenent LT, Bell ME, Hay AG, Peterson DA, Walter J, Vijay-Kumar M, Gewirtz AT, Ley RE | Cell host & microbe | 24237702 | Cell Host Microbe | 2013 Nov 13 | https://www.ncbi.nlm.nih.gov/pubmed/24237702 |
Human genetics shape the gut microbiome. | Goodrich JK, Waters JL, Poole AC, Sutter JL, Koren O, Blekhman R, Beaumont M, Van Treuren W, Knight R, Bell JT, Spector TD, Clark AG, Ley RE | Cell | 25417156 | Cell | 2014 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/25417156 |
Resilience of small intestinal beneficial bacteria to the toxicity of soybean oil fatty acids. | Di Rienzi SC, Jacobson J, Kennedy EA, Bell ME, Shi Q, Waters JL, Lawrence P, Brenna JT, Britton RA, Walter J, Ley RE | eLife | 29580380 | Elife | 2018 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/29580380 |
Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women. | Menni C, Zierer J, Pallister T, Jackson MA, Long T, Mohney RP, Steves CJ, Spector TD, Valdes AM | Scientific reports | 28894110 | Sci Rep | 2017 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/28894110 |
A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units. | Jackson MA, Bell JT, Spector TD, Steves CJ | PeerJ | 27635321 | PeerJ | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27635321 |
Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice. | Carvalho FA, Koren O, Goodrich JK, Johansson ME, Nalbantoglu I, Aitken JD, Su Y, Chassaing B, Walters WA, González A, Clemente JC, Cullender TC, Barnich N, Darfeuille-Michaud A, Vijay-Kumar M, Knight R, Ley RE, Gewirtz AT | Cell host & microbe | 22863420 | Cell Host Microbe | 2012 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/22863420 |
Virome Diversity Correlates with Intestinal Microbiome Diversity in Adult Monozygotic Twins. | Moreno-Gallego JL, Chou SP, Di Rienzi SC, Goodrich JK, Spector TD, Bell JT, Youngblut ND, Hewson I, Reyes A, Ley RE | Cell host & microbe | 30763537 | Cell Host Microbe | 2019 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/30763537 |
Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis. | Carvalho FA, Nalbantoglu I, Ortega-Fernandez S, Aitken JD, Su Y, Koren O, Walters WA, Knight R, Ley RE, Vijay-Kumar M, Gewirtz AT | Gut | 21646247 | Gut | 2012 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21646247 |
An Investigation Into Physical Frailty as a Link Between the Gut Microbiome and Cognitive Health. | Verdi S, Jackson MA, Beaumont M, Bowyer RCE, Bell JT, Spector TD, Steves CJ | Frontiers in aging neuroscience | 30564113 | Front Aging Neurosci | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30564113 |
Red Wine Consumption Associated With Increased Gut Microbiota α-Diversity in 3 Independent Cohorts. | Le Roy CI, Wells PM, Si J, Raes J, Bell JT, Spector TD | Gastroenterology | 31472153 | Gastroenterology | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31472153 |
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. | Wang J, Kurilshikov A, Radjabzadeh D, Turpin W, Croitoru K, Bonder MJ, Jackson MA, Medina-Gomez C, Frost F, Homuth G, Rühlemann M, Hughes D, Kim HN, MiBioGen Consortium Initiative, Spector TD, Bell JT, Steves CJ, Timpson N, Franke A, Wijmenga C, Meyer K, Kacprowski T, Franke L, Paterson AD, Raes J, Kraaij R, Zhernakova A | Microbiome | 29880062 | Microbiome | 2018 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/29880062 |
Genetic Determinants of the Gut Microbiome in UK Twins. | Goodrich JK, Davenport ER, Beaumont M, Jackson MA, Knight R, Ober C, Spector TD, Bell JT, Clark AG, Ley RE | Cell host & microbe | 27173935 | Cell Host Microbe | 2016 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/27173935 |
Proton pump inhibitors alter the composition of the gut microbiota. | Jackson MA, Goodrich JK, Maxan ME, Freedberg DE, Abrams JA, Poole AC, Sutter JL, Welter D, Ley RE, Bell JT, Spector TD, Steves CJ | Gut | 26719299 | Gut | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26719299 |
AIEC pathobiont instigates chronic colitis in susceptible hosts by altering microbiota composition. | Chassaing B, Koren O, Carvalho FA, Ley RE, Gewirtz AT | Gut | 23896971 | Gut | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23896971 |
The microbiome affects liver sphingolipids and plasma fatty acids in a murine model of the Western diet based on soybean oil. | Di Rienzi SC, Johnson EL, Waters JL, Kennedy EA, Jacobson J, Lawrence P, Wang DH, Worgall TS, Brenna JT, Ley RE | The Journal of nutritional biochemistry | 34186211 | J Nutr Biochem | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34186211 |
Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome. | Xie H, Guo R, Zhong H, Feng Q, Lan Z, Qin B, Ward KJ, Jackson MA, Xia Y, Chen X, Chen B, Xia H, Xu C, Li F, Xu X, Al-Aama JY, Yang H, Wang J, Kristiansen K, Wang J, Steves CJ, Bell JT, Li J, Spector TD, Jia H | Cell systems | 27818083 | Cell Syst | 2016 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/27818083 |
ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins. | Davenport ER, Goodrich JK, Bell JT, Spector TD, Ley RE, Clark AG | BMC genomics | 27871240 | BMC Genomics | 2016 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/27871240 |
Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome. | Pallister T, Jackson MA, Martin TC, Zierer J, Jennings A, Mohney RP, MacGregor A, Steves CJ, Cassidy A, Spector TD, Menni C | Scientific reports | 29057986 | Sci Rep | 2017 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/29057986 |
Gut microbial diversity is associated with lower arterial stiffness in women. | Menni C, Lin C, Cecelja M, Mangino M, Matey-Hernandez ML, Keehn L, Mohney RP, Steves CJ, Spector TD, Kuo CF, Chowienczyk P, Valdes AM | European heart journal | 29750272 | Eur Heart J | 2018 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/29750272 |
Detection of stable community structures within gut microbiota co-occurrence networks from different human populations. | Jackson MA, Bonder MJ, Kuncheva Z, Zierer J, Fu J, Kurilshikov A, Wijmenga C, Zhernakova A, Bell JT, Spector TD, Steves CJ | PeerJ | 29441232 | PeerJ | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29441232 |
Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels. | Johnson EL, Heaver SL, Waters JL, Kim BI, Bretin A, Goodman AL, Gewirtz AT, Worgall TS, Ley RE | Nature communications | 32424203 | Nat Commun | 2020 May 18 | https://www.ncbi.nlm.nih.gov/pubmed/32424203 |
Gut microbiota associations with common diseases and prescription medications in a population-based cohort. | Jackson MA, Verdi S, Maxan ME, Shin CM, Zierer J, Bowyer RCE, Martin T, Williams FMK, Menni C, Bell JT, Spector TD, Steves CJ | Nature communications | 29985401 | Nat Commun | 2018 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/29985401 |
Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome. | Le Roy CI, Kurilshikov A, Leeming ER, Visconti A, Bowyer RCE, Menni C, Falchi M, Koutnikova H, Veiga P, Zhernakova A, Derrien M, Spector TD | BMC microbiology | 35114943 | BMC Microbiol | 2022 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/35114943 |
Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD. | Awojoodu AO, Keegan PM, Lane AR, Zhang Y, Lynch KR, Platt MO, Botchwey EA | Blood | 25075126 | Blood | 2014 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/25075126 |
Pro-atherogenic shear stress and HIV proteins synergistically upregulate cathepsin K in endothelial cells. | Parker IK, Roberts LM, Hansen L, Gleason RL Jr, Sutliff RL, Platt MO | Annals of biomedical engineering | 24719048 | Ann Biomed Eng | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24719048 |
Biomechanical and biochemical regulation of cathepsin K expression in endothelial cells converge at AP-1 and NF-κB. | Keegan PM, Anbazhakan S, Kang B, Pace BS, Platt MO | Biological chemistry | 26760306 | Biol Chem | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26760306 |
Patient specific proteolytic activity of monocyte-derived macrophages and osteoclasts predicted with temporal kinase activation states during differentiation. | Park KY, Li WA, Platt MO | Integrative biology : quantitative biosciences from nano to macro | 23114878 | Integr Biol (Camb) | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23114878 |
Endothelial cells and cathepsins: Biochemical and biomechanical regulation. | Platt MO, Shockey WA | Biochimie | 26458976 | Biochimie | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26458976 |
PACMANS: A bioinformatically informed algorithm to predict, design, and disrupt protease-on-protease hydrolysis. | Ferrall-Fairbanks MC, Barry ZT, Affer M, Shuler MA, Moomaw EW, Platt MO | Protein science : a publication of the Protein Society | 28078782 | Protein Sci | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/28078782 |
Experimental and imaging techniques for examining fibrin clot structures in normal and diseased states. | Fan NK, Keegan PM, Platt MO, Averett RD | Journal of visualized experiments : JoVE | 25867016 | J Vis Exp | 2015 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/25867016 |
Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues. | Wilder CL, Park KY, Keegan PM, Platt MO | Archives of biochemistry and biophysics | 21982919 | Arch Biochem Biophys | 2011 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/21982919 |
Age-dependent characterization of carotid and cerebral artery geometries in a transgenic mouse model of sickle cell anemia using ultrasound and microcomputed tomography. | Rivera CP, Li L, Cai S, Pei N, McAlear GE, Bollavaram K, Ariyo OV, Omojola VO, Song H, Alfonso AL, Tan W, Huo Y, Platt MO | Blood cells, molecules & diseases | 32841841 | Blood Cells Mol Dis | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32841841 |
Microarchitectural and mechanical characterization of the sickle bone. | Green M, Akinsami I, Lin A, Banton S, Ghosh S, Chen B, Platt M, Osunkwo I, Ofori-Acquah S, Guldberg R, Barabino G | Journal of the mechanical behavior of biomedical materials | 25957113 | J Mech Behav Biomed Mater | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/25957113 |
Sickle cell disease activates peripheral blood mononuclear cells to induce cathepsins k and v activity in endothelial cells. | Keegan PM, Surapaneni S, Platt MO | Anemia | 22550569 | Anemia | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22550569 |
Reassessing enzyme kinetics: Considering protease-as-substrate interactions in proteolytic networks. | Ferrall-Fairbanks MC, Kieslich CA, Platt MO | Proceedings of the National Academy of Sciences of the United States of America | 31980525 | Proc Natl Acad Sci U S A | 2020 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/31980525 |
Original Research: Sickle cell anemia and pediatric strokes: Computational fluid dynamics analysis in the middle cerebral artery. | Rivera CP, Veneziani A, Ware RE, Platt MO | Experimental biology and medicine (Maywood, N.J.) | 26946534 | Exp Biol Med (Maywood) | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26946534 |
Tumor necrosis factor alpha stimulates cathepsin K and V activity via juxtacrine monocyte-endothelial cell signaling and JNK activation. | Keegan PM, Wilder CL, Platt MO | Molecular and cellular biochemistry | 22562303 | Mol Cell Biochem | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22562303 |
Cathepsin S cannibalism of cathepsin K as a mechanism to reduce type I collagen degradation. | Barry ZT, Platt MO | The Journal of biological chemistry | 22730330 | J Biol Chem | 2012 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/22730330 |
Cathepsin Protease Inhibition Reduces Endometriosis Lesion Establishment. | Porter KM, Wieser FA, Wilder CL, Sidell N, Platt MO | Reproductive sciences (Thousand Oaks, Calif.) | 26482207 | Reprod Sci | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26482207 |
Sickle Cell Anemia Mediates Carotid Artery Expansive Remodeling That Can Be Prevented by Inhibition of JNK (c-Jun N-Terminal Kinase). | Song H, Keegan PM, Anbazhakan S, Rivera CP, Feng Y, Omojola VO, Clark AA, Cai S, Selma J, Gleason RL Jr, Botchwey EA, Huo Y, Tan W, Platt MO | Arteriosclerosis, thrombosis, and vascular biology | 32160775 | Arterioscler Thromb Vasc Biol | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32160775 |
Low-Cost Method to Monitor Patient Adherence to HIV Antiretroviral Therapy Using Multiplex Cathepsin Zymography. | Platt MO, Evans D, Keegan PM, McNamara L, Parker IK, Roberts LM, Caulk AW, Gleason RL Jr, Seifu D, Amogne W, Penny C | Molecular biotechnology | 26589706 | Mol Biotechnol | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/26589706 |
Optogenetic Approaches to Drug Discovery in Neuroscience and Beyond. | Zhang H, Cohen AE | Trends in biotechnology | 28552428 | Trends Biotechnol | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28552428 |
Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing. | Werley CA, Chien MP, Gaublomme J, Shekhar K, Butty V, Yi BA, Kralj JM, Bloxham BB, Boyer LA, Regev A, Cohen AE | PloS one | 28333933 | PLoS One | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28333933 |
Bright and fast multicoloured voltage reporters via electrochromic FRET. | Zou P, Zhao Y, Douglass AD, Hochbaum DR, Brinks D, Werley CA, Harrison DJ, Campbell RE, Cohen AE | Nature communications | 25118186 | Nat Commun | 2014 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/25118186 |
A Bright and Fast Red Fluorescent Protein Voltage Indicator That Reports Neuronal Activity in Organotypic Brain Slices. | Abdelfattah AS, Farhi SL, Zhao Y, Brinks D, Zou P, Ruangkittisakul A, Platisa J, Pieribone VA, Ballanyi K, Cohen AE, Campbell RE | The Journal of neuroscience : the official journal of the Society for Neuroscience | 26911693 | J Neurosci | 2016 Feb 24 | https://www.ncbi.nlm.nih.gov/pubmed/26911693 |
All-Optical Electrophysiology for High-Throughput Functional Characterization of a Human iPSC-Derived Motor Neuron Model of ALS. | Kiskinis E, Kralj JM, Zou P, Weinstein EN, Zhang H, Tsioras K, Wiskow O, Ortega JA, Eggan K, Cohen AE | Stem cell reports | 29779896 | Stem Cell Reports | 2018 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/29779896 |
Ultrasensitive measurements of microbial rhodopsin photocycles using photochromic FRET. | Bayraktar H, Fields AP, Kralj JM, Spudich JL, Rothschild KJ, Cohen AE | Photochemistry and photobiology | 22010969 | Photochem Photobiol | 2012 Jan-Feb | https://www.ncbi.nlm.nih.gov/pubmed/22010969 |
Imaging GFP-based reporters in neurons with multiwavelength optogenetic control. | Venkatachalam V, Cohen AE | Biophysical journal | 25296307 | Biophys J | 2014 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/25296307 |
Optogenetics: Turning the Microscope on Its Head. | Cohen AE | Biophysical journal | 26958872 | Biophys J | 2016 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/26958872 |
Mechanism of voltage-sensitive fluorescence in a microbial rhodopsin. | Maclaurin D, Venkatachalam V, Lee H, Cohen AE | Proceedings of the National Academy of Sciences of the United States of America | 23530193 | Proc Natl Acad Sci U S A | 2013 Apr 9 | https://www.ncbi.nlm.nih.gov/pubmed/23530193 |
All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins. | Hochbaum DR, Zhao Y, Farhi SL, Klapoetke N, Werley CA, Kapoor V, Zou P, Kralj JM, Maclaurin D, Smedemark-Margulies N, Saulnier JL, Boulting GL, Straub C, Cho YK, Melkonian M, Wong GK, Harrison DJ, Murthy VN, Sabatini BL, Boyden ES, Campbell RE, Cohen AE | Nature methods | 24952910 | Nat Methods | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24952910 |
Simultaneous mapping of membrane voltage and calcium in zebrafish heart in vivo reveals chamber-specific developmental transitions in ionic currents. | Hou JH, Kralj JM, Douglass AD, Engert F, Cohen AE | Frontiers in physiology | 25309445 | Front Physiol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25309445 |
Photostick: a method for selective isolation of target cells from culture. | Chien MP, Werley CA, Farhi SL, Cohen AE | Chemical science | 25705368 | Chem Sci | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25705368 |
Flash memory: photochemical imprinting of neuronal action potentials onto a microbial rhodopsin. | Venkatachalam V, Brinks D, Maclaurin D, Hochbaum D, Kralj J, Cohen AE | Journal of the American Chemical Society | 24428326 | J Am Chem Soc | 2014 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/24428326 |
A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store. | Henderson MJ, Baldwin HA, Werley CA, Boccardo S, Whitaker LR, Yan X, Holt GT, Schreiter ER, Looger LL, Cohen AE, Kim DS, Harvey BK | PloS one | 26451944 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26451944 |
Measuring membrane voltage with microbial rhodopsins. | Cohen AE, Hochbaum DR | Methods in molecular biology (Clifton, N.J.) | 24052383 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24052383 |
Bringing bioelectricity to light. | Cohen AE, Venkatachalam V | Annual review of biophysics | 24773017 | Annu Rev Biophys | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24773017 |
Screening fluorescent voltage indicators with spontaneously spiking HEK cells. | Park J, Werley CA, Venkatachalam V, Kralj JM, Dib-Hajj SD, Waxman SG, Cohen AE | PloS one | 24391999 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24391999 |
Convex lens-induced confinement for imaging single molecules. | Leslie SR, Fields AP, Cohen AE | Analytical chemistry | 20557026 | Anal Chem | 2010 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/20557026 |
All-Optical Interrogation of Neural Circuits. | Emiliani V, Cohen AE, Deisseroth K, Häusser M | The Journal of neuroscience : the official journal of the Society for Neuroscience | 26468193 | J Neurosci | 2015 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/26468193 |
Temporal dynamics of microbial rhodopsin fluorescence reports absolute membrane voltage. | Hou JH, Venkatachalam V, Cohen AE | Biophysical journal | 24507604 | Biophys J | 2014 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/24507604 |
Optical recording of action potentials in mammalian neurons using a microbial rhodopsin. | Kralj JM, Douglass AD, Hochbaum DR, Maclaurin D, Cohen AE | Nature methods | 22120467 | Nat Methods | 2011 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/22120467 |
Voltage imaging with genetically encoded indicators. | Xu Y, Zou P, Cohen AE | Current opinion in chemical biology | 28460291 | Curr Opin Chem Biol | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28460291 |
Two-Photon Lifetime Imaging of Voltage Indicating Proteins as a Probe of Absolute Membrane Voltage. | Brinks D, Klein AJ, Cohen AE | Biophysical journal | 26331249 | Biophys J | 2015 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/26331249 |
Ribosomal elongation factor 4 promotes cell death associated with lethal stress. | Li L, Hong Y, Luan G, Mosel M, Malik M, Drlica K, Zhao X | mBio | 25491353 | mBio | 2014 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/25491353 |
Suppression of Reactive Oxygen Species Accumulation Accounts for Paradoxical Bacterial Survival at High Quinolone Concentration. | Luan G, Hong Y, Drlica K, Zhao X | Antimicrobial agents and chemotherapy | 29229642 | Antimicrob Agents Chemother | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29229642 |
Contribution of reactive oxygen species to thymineless death in Escherichia coli. | Hong Y, Li L, Luan G, Drlica K, Zhao X | Nature microbiology | 28970486 | Nat Microbiol | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/28970486 |
Inhibitors of reactive oxygen species accumulation delay and/or reduce the lethality of several antistaphylococcal agents. | Liu Y, Liu X, Qu Y, Wang X, Li L, Zhao X | Antimicrobial agents and chemotherapy | 22948880 | Antimicrob Agents Chemother | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/22948880 |
Moving forward with reactive oxygen species involvement in antimicrobial lethality. | Zhao X, Hong Y, Drlica K | The Journal of antimicrobial chemotherapy | 25422287 | J Antimicrob Chemother | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25422287 |
Resveratrol Antagonizes Antimicrobial Lethality and Stimulates Recovery of Bacterial Mutants. | Liu Y, Zhou J, Qu Y, Yang X, Shi G, Wang X, Hong Y, Drlica K, Zhao X | PloS one | 27045517 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27045517 |
YihE kinase is a central regulator of programmed cell death in bacteria. | Dorsey-Oresto A, Lu T, Mosel M, Wang X, Salz T, Drlica K, Zhao X | Cell reports | 23416055 | Cell Rep | 2013 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/23416055 |
Dimethyl Sulfoxide Protects Escherichia coli from Rapid Antimicrobial-Mediated Killing. | Mi H, Wang D, Xue Y, Zhang Z, Niu J, Hong Y, Drlica K, Zhao X | Antimicrobial agents and chemotherapy | 27246776 | Antimicrob Agents Chemother | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27246776 |
Lethal synergy involving bicyclomycin: an approach for reviving old antibiotics. | Malik M, Li L, Zhao X, Kerns RJ, Berger JM, Drlica K | The Journal of antimicrobial chemotherapy | 25085655 | J Antimicrob Chemother | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25085655 |
Superoxide-mediated protection of Escherichia coli from antimicrobials. | Mosel M, Li L, Drlica K, Zhao X | Antimicrobial agents and chemotherapy | 23979754 | Antimicrob Agents Chemother | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23979754 |
Reactive oxygen species and the bacterial response to lethal stress. | Zhao X, Drlica K | Current opinion in microbiology | 25078317 | Curr Opin Microbiol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25078317 |
Post-stress bacterial cell death mediated by reactive oxygen species. | Hong Y, Zeng J, Wang X, Drlica K, Zhao X | Proceedings of the National Academy of Sciences of the United States of America | 30948634 | Proc Natl Acad Sci U S A | 2019 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/30948634 |
Involvement of Holliday junction resolvase in fluoroquinolone-mediated killing of Mycobacterium smegmatis. | Long Q, Du Q, Fu T, Drlica K, Zhao X, Xie J | Antimicrobial agents and chemotherapy | 25534729 | Antimicrob Agents Chemother | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25534729 |
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. | Blaschke K, Ebata KT, Karimi MM, Zepeda-Martínez JA, Goyal P, Mahapatra S, Tam A, Laird DJ, Hirst M, Rao A, Lorincz MC, Ramalho-Santos M | Nature | 23812591 | Nature | 2013 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/23812591 |
Follicle dynamics and global organization in the intact mouse ovary. | Faire M, Skillern A, Arora R, Nguyen DH, Wang J, Chamberlain C, German MS, Fung JC, Laird DJ | Developmental biology | 25889274 | Dev Biol | 2015 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/25889274 |
Wnt and Bmp fit germ cells to a T. | Cantú AV, Laird DJ | Developmental cell | 24331924 | Dev Cell | 2013 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/24331924 |
A Roadmap for Three-Dimensional Analysis of the Intact Mouse Ovary. | Soygur B, Foecke MH, Gaylord EA, Fries A, Li J, Arora R, Laird DJ | Methods in molecular biology (Clifton, N.J.) | 37464244 | Methods Mol Biol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37464244 |
Sustained fertility from first-wave follicle oocytes that pause their growth. | Soygur B, Gaylord EA, Foecke MH, Cincotta SA, Horan TS, Wood A, Cohen PE, Laird DJ | bioRxiv : the preprint server for biology | 39253445 | bioRxiv | 2024 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/39253445 |
Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling. | Cantú AV, Altshuler-Keylin S, Laird DJ | The Journal of cell biology | 27402951 | J Cell Biol | 2016 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/27402951 |
Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates. | Susman MW, Karuna EP, Kunz RC, Gujral TS, Cantú AV, Choi SS, Jong BY, Okada K, Scales MK, Hum J, Hu LS, Kirschner MW, Nishinakamura R, Yamada S, Laird DJ, Jao LE, Gygi SP, Greenberg ME, Ho HH | eLife | 28885975 | Elife | 2017 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/28885975 |
Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele. | Chen L, Faire M, Kissner MD, Laird DJ | Human molecular genetics | 23077213 | Hum Mol Genet | 2013 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/23077213 |
Novel domains of expression for orphan receptor tyrosine kinase Ror2 in the human and mouse reproductive system. | Arora R, Altman E, Tran ND, Laird DJ | Developmental dynamics : an official publication of the American Association of Anatomists | 24753105 | Dev Dyn | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24753105 |
Meiotic onset is reliant on spatial distribution but independent of germ cell number in the mouse ovary. | Arora R, Abby E, Ross AD, Cantu AV, Kissner MD, Castro V, Ho HY, Livera G, Laird DJ | Journal of cell science | 27199373 | J Cell Sci | 2016 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/27199373 |
Apoptosis in the fetal testis eliminates developmentally defective germ cell clones. | Nguyen DH, Soygur B, Peng SP, Malki S, Hu G, Laird DJ | Nature cell biology | 33199844 | Nat Cell Biol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33199844 |
Humans put their eggs in more than one basket. | Laird DJ | Nature cell biology | 23263370 | Nat Cell Biol | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23263370 |
Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity. | Chen JC, Hoffman JR, Arora R, Perrone LA, Gonzalez-Gomez CJ, Vo KC, Laird DJ, Irwin JC, Giudice LC | Fertility and sterility | 26515378 | Fertil Steril | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26515378 |
A miR-372/let-7 Axis Regulates Human Germ Versus Somatic Cell Fates. | Tran ND, Kissner M, Subramanyam D, Parchem RJ, Laird DJ, Blelloch RH | Stem cells (Dayton, Ohio) | 27066911 | Stem Cells | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27066911 |
A pilgrim's progress: Seeking meaning in primordial germ cell migration. | Cantú AV, Laird DJ | Stem cell research | 28754603 | Stem Cell Res | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28754603 |
Smad4 regulates growth plate matrix production and chondrocyte polarity. | Whitaker AT, Berthet E, Cantu A, Laird DJ, Alliston T | Biology open | 28167493 | Biol Open | 2017 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/28167493 |
Heterogeneity of primordial germ cells. | Nguyen DH, Jaszczak RG, Laird DJ | Current topics in developmental biology | 31155358 | Curr Top Dev Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31155358 |
Ror2 enhances polarity and directional migration of primordial germ cells. | Laird DJ, Altshuler-Keylin S, Kissner MD, Zhou X, Anderson KV | PLoS genetics | 22216013 | PLoS Genet | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22216013 |
Insights from imaging the implanting embryo and the uterine environment in three dimensions. | Arora R, Fries A, Oelerich K, Marchuk K, Sabeur K, Giudice LC, Laird DJ | Development (Cambridge, England) | 27836961 | Development | 2016 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/27836961 |
Patterning of sharp cellular interfaces with a reconfigurable elastic substrate. | Curtis A, Li DJ, DeVeale B, Onishi K, Kim MY, Blelloch R, Laird DJ, Hui EE | Integrative biology : quantitative biosciences from nano to macro | 28001149 | Integr Biol (Camb) | 2017 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/28001149 |
Natural selection at the cellular level: insights from male germ cell differentiation. | Nguyen DH, Laird DJ | Cell death and differentiation | 34079077 | Cell Death Differ | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34079077 |
DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation. | Sousa Martins JP, Liu X, Oke A, Arora R, Franciosi F, Viville S, Laird DJ, Fung JC, Conti M | Journal of cell science | 26826184 | J Cell Sci | 2016 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/26826184 |
Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrants. | Jaszczak RG, Zussman JW, Wagner DE, Laird DJ | bioRxiv : the preprint server for biology | 39257761 | bioRxiv | 2024 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/39257761 |
Comparative epigenomics: defining and utilizing epigenomic variations across species, time-course, and individuals. | Xiao S, Cao X, Zhong S | Wiley interdisciplinary reviews. Systems biology and medicine | 25044241 | Wiley Interdiscip Rev Syst Biol Med | 2014 Sep-Oct | https://www.ncbi.nlm.nih.gov/pubmed/25044241 |
Cell fate inclination within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing. | Biase FH, Cao X, Zhong S | Genome research | 25096407 | Genome Res | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25096407 |
Comparative epigenomic annotation of regulatory DNA. | Xiao S, Xie D, Cao X, Yu P, Xing X, Chen CC, Musselman M, Xie M, West FD, Lewin HA, Wang T, Zhong S | Cell | 22682255 | Cell | 2012 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/22682255 |
SMARCAD1 Contributes to the Regulation of Naive Pluripotency by Interacting with Histone Citrullination. | Xiao S, Lu J, Sridhar B, Cao X, Yu P, Zhao T, Chen CC, McDee D, Sloofman L, Wang Y, Rivas-Astroza M, Telugu BPVL, Levasseur D, Zhang K, Liang H, Zhao JC, Tanaka TS, Stormo G, Zhong S | Cell reports | 28355564 | Cell Rep | 2017 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/28355564 |
Spatiotemporal clustering of the epigenome reveals rules of dynamic gene regulation. | Yu P, Xiao S, Xin X, Song CX, Huang W, McDee D, Tanaka T, Wang T, He C, Zhong S | Genome research | 23033340 | Genome Res | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23033340 |
From genomes to societies: a holistic view of determinants of human health. | Shi Y, Zhong S | Current opinion in biotechnology | 24686286 | Curr Opin Biotechnol | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24686286 |
Enabling interspecies epigenomic comparison with CEpBrowser. | Cao X, Zhong S | Bioinformatics (Oxford, England) | 23543396 | Bioinformatics | 2013 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/23543396 |
The p23 molecular chaperone and GCN5 acetylase jointly modulate protein-DNA dynamics and open chromatin status. | Zelin E, Zhang Y, Toogun OA, Zhong S, Freeman BC | Molecular cell | 23022381 | Mol Cell | 2012 Nov 9 | https://www.ncbi.nlm.nih.gov/pubmed/23022381 |
Time-variant clustering model for understanding cell fate decisions. | Huang W, Cao X, Biase FH, Yu P, Zhong S | Proceedings of the National Academy of Sciences of the United States of America | 25339442 | Proc Natl Acad Sci U S A | 2014 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/25339442 |
Understanding variation in transcription factor binding by modeling transcription factor genome-epigenome interactions. | Chen CC, Xiao S, Xie D, Cao X, Song CX, Wang T, He C, Zhong S | PLoS computational biology | 24339764 | PLoS Comput Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24339764 |
Mapping personal functional data to personal genomes. | Rivas-Astroza M, Xie D, Cao X, Zhong S | Bioinformatics (Oxford, England) | 22006915 | Bioinformatics | 2011 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/22006915 |
Towards an evolutionary model of transcription networks. | Xie D, Chen CC, He X, Cao X, Zhong S | PLoS computational biology | 21695281 | PLoS Comput Biol | 2011 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21695281 |
The epichaperome is an integrated chaperome network that facilitates tumour survival. | Rodina A, Wang T, Yan P, Gomes ED, Dunphy MP, Pillarsetty N, Koren J, Gerecitano JF, Taldone T, Zong H, Caldas-Lopes E, Alpaugh M, Corben A, Riolo M, Beattie B, Pressl C, Peter RI, Xu C, Trondl R, Patel HJ, Shimizu F, Bolaender A, Yang C, Panchal P, Farooq MF, Kishinevsky S, Modi S, Lin O, Chu F, Patil S, Erdjument-Bromage H, Zanzonico P, Hudis C, Studer L, Roboz GJ, Cesarman E, Cerchietti L, Levine R, Melnick A, Larson SM, Lewis JS, Guzman ML, Chiosis G | Nature | 27706135 | Nature | 2016 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/27706135 |
Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia. | Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC | Molecular cancer therapeutics | 24934933 | Mol Cancer Ther | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24934933 |
Concise review: Leukemia stem cells in personalized medicine. | Guzman ML, Allan JN | Stem cells (Dayton, Ohio) | 24214290 | Stem Cells | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24214290 |
In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche. | Zong H, Sen S, Zhang G, Mu C, Albayati ZF, Gorenstein DG, Liu X, Ferrari M, Crooks PA, Roboz GJ, Shen H, Guzman ML | Leukemia | 26669973 | Leukemia | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26669973 |
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. | Geng H, Brennan S, Milne TA, Chen WY, Li Y, Hurtz C, Kweon SM, Zickl L, Shojaee S, Neuberg D, Huang C, Biswas D, Xin Y, Racevskis J, Ketterling RP, Luger SM, Lazarus H, Tallman MS, Rowe JM, Litzow MR, Guzman ML, Allis CD, Roeder RG, Müschen M, Paietta E, Elemento O, Melnick AM | Cancer discovery | 23107779 | Cancer Discov | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23107779 |
A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species. | Zong H, Gozman A, Caldas-Lopes E, Taldone T, Sturgill E, Brennan S, Ochiana SO, Gomes-DaGama EM, Sen S, Rodina A, Koren J 3rd, Becker MW, Rudin CM, Melnick A, Levine RL, Roboz GJ, Nimer SD, Chiosis G, Guzman ML | Cell reports | 26628369 | Cell Rep | 2015 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/26628369 |
Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia. | Roboz GJ, Ritchie EK, Dault Y, Lam L, Marshall DC, Cruz NM, Hsu HC, Hassane DC, Christos PJ, Ippoliti C, Scandura JM, Guzman ML | Haematologica | 29724902 | Haematologica | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29724902 |
Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity. | Sen S, Hassane DC, Corbett C, Becker MW, Jordan CT, Guzman ML | Experimental hematology | 23660068 | Exp Hematol | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23660068 |
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia. | Klossowski S, Miao H, Kempinska K, Wu T, Purohit T, Kim E, Linhares BM, Chen D, Jih G, Perkey E, Huang H, He M, Wen B, Wang Y, Yu K, Lee SC, Danet-Desnoyers G, Trotman W, Kandarpa M, Cotton A, Abdel-Wahab O, Lei H, Dou Y, Guzman M, Peterson L, Gruber T, Choi S, Sun D, Ren P, Li LS, Liu Y, Burrows F, Maillard I, Cierpicki T, Grembecka J | The Journal of clinical investigation | 31855575 | J Clin Invest | 2020 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/31855575 |
Single-cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3-ITD-mutated AML stem/progenitor cells. | Han L, Qiu P, Zeng Z, Jorgensen JL, Mak DH, Burks JK, Schober W, McQueen TJ, Cortes J, Tanner SD, Roboz GJ, Kantarjian HM, Kornblau SM, Guzman ML, Andreeff M, Konopleva M | Cytometry. Part A : the journal of the International Society for Analytical Cytology | 25598437 | Cytometry A | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25598437 |
Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy. | Taldone T, Gomes-DaGama EM, Zong H, Sen S, Alpaugh ML, Zatorska D, Alonso-Sabadell R, Guzman ML, Chiosis G | Bioorganic & medicinal chemistry letters | 21802945 | Bioorg Med Chem Lett | 2011 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/21802945 |
Acute myelogenous leukemia stem cells: from Bench to Bedside. | Felipe Rico J, Hassane DC, Guzman ML | Cancer letters | 22713929 | Cancer Lett | 2013 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/22713929 |
Acute myeloid leukemia stem cells: seek and destroy. | Roboz GJ, Guzman M | Expert review of hematology | 21082958 | Expert Rev Hematol | 2009 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21082958 |
Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin. | Madadi NR, Zong H, Ketkar A, Zheng C, Penthala NR, Janganati V, Bommagani S, Eoff RL, Guzman ML, Crooks PA | MedChemComm | 26257861 | Medchemcomm | 2015 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/26257861 |
Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. | Illendula A, Gilmour J, Grembecka J, Tirumala VSS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, Mishra L, Adli M, Castilla LH, Rajewski RA, Janes KA, Guzman ML, Bonifer C, Bushweller JH | EBioMedicine | 27428424 | EBioMedicine | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27428424 |
Is minimal residual disease monitoring clinically relevant in adults with acute myelogenous leukemia? | Carlson KS, Guzman ML | Current hematologic malignancy reports | 23563936 | Curr Hematol Malig Rep | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23563936 |
A phase I study using bortezomib with weekly idarubicin for treatment of elderly patients with acute myeloid leukemia. | Howard DS, Liesveld J, Phillips GL 2nd, Hayslip J, Weiss H, Jordan CT, Guzman ML | Leukemia research | 24075534 | Leuk Res | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24075534 |
Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells. | Bystrom LM, Bezerra DP, Hsu HT, Zong H, Lara-Martínez LA, De Leon JP, Emmanuel M, Méry D, Gardenghi S, Hassane D, Neto CC, Cunningham-Rundles S, Becker MW, Rivella S, Guzman ML | Blood advances | 31698457 | Blood Adv | 2019 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/31698457 |
Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture. | Nasim S, Guzman ML, Jordan CT, Crooks PA | Bioorganic & medicinal chemistry letters | 21757349 | Bioorg Med Chem Lett | 2011 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/21757349 |
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90. | Moulick K, Ahn JH, Zong H, Rodina A, Cerchietti L, Gomes DaGama EM, Caldas-Lopes E, Beebe K, Perna F, Hatzi K, Vu LP, Zhao X, Zatorska D, Taldone T, Smith-Jones P, Alpaugh M, Gross SS, Pillarsetty N, Ku T, Lewis JS, Larson SM, Levine R, Erdjument-Bromage H, Guzman ML, Nimer SD, Melnick A, Neckers L, Chiosis G | Nature chemical biology | 21946277 | Nat Chem Biol | 2011 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/21946277 |
Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents. | Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA | European journal of medicinal chemistry | 25557492 | Eur J Med Chem | 2015 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/25557492 |
Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. | Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, Sen S, Zhou Y, Boulton A, Kuntimaddi A, Gao Y, Rajewski RA, Guzman ML, Castilla LH, Bushweller JH | Science (New York, N.Y.) | 25678665 | Science | 2015 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/25678665 |
Dehydroleucodine, a Sesquiterpene Lactone from Gynoxys verrucosa, Demonstrates Cytotoxic Activity against Human Leukemia Cells. | Ordóñez PE, Sharma KK, Bystrom LM, Alas MA, Enriquez RG, Malagón O, Jones DE, Guzman ML, Compadre CM | Journal of natural products | 27057812 | J Nat Prod | 2016 Apr 22 | https://www.ncbi.nlm.nih.gov/pubmed/27057812 |
Three-dimensional carbon nanotube scaffolds for long-term maintenance and expansion of human mesenchymal stem cells. | Lalwani G, D'agati M, Gopalan A, Patel SC, Talukdar Y, Sitharaman B | Journal of biomedical materials research. Part A | 28295953 | J Biomed Mater Res A | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28295953 |
Structural disruption increases toxicity of graphene nanoribbons. | Mullick Chowdhury S, Dasgupta S, McElroy AE, Sitharaman B | Journal of applied toxicology : JAT | 25224919 | J Appl Toxicol | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25224919 |
Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme. | Chowdhury SM, Surhland C, Sanchez Z, Chaudhary P, Suresh Kumar MA, Lee S, Peña LA, Waring M, Sitharaman B, Naidu M | Nanomedicine : nanotechnology, biology, and medicine | 25131339 | Nanomedicine | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25131339 |
The effects of graphene nanostructures on mesenchymal stem cells. | Talukdar Y, Rashkow J, Lalwani G, Kanakia S, Sitharaman B | Biomaterials | 24674462 | Biomaterials | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24674462 |
Quantification of single-cell nanoparticle concentrations and the distribution of these concentrations in cell population. | Rashkow JT, Patel SC, Tappero R, Sitharaman B | Journal of the Royal Society, Interface | 24554576 | J R Soc Interface | 2014 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/24554576 |
Two-dimensional nanostructure-reinforced biodegradable polymeric nanocomposites for bone tissue engineering. | Lalwani G, Henslee AM, Farshid B, Lin L, Kasper FK, Qin YX, Mikos AG, Sitharaman B | Biomacromolecules | 23405887 | Biomacromolecules | 2013 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/23405887 |
Multiscale photoacoustic microscopy of single-walled carbon nanotube-incorporated tissue engineering scaffolds. | Cai X, Paratala BS, Hu S, Sitharaman B, Wang LV | Tissue engineering. Part C, Methods | 22082018 | Tissue Eng Part C Methods | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22082018 |
A novel nanoparticle-enhanced photoacoustic stimulus for bone tissue engineering. | Sitharaman B, Avti PK, Schaefer K, Talukdar Y, Longtin JP | Tissue engineering. Part A | 21395444 | Tissue Eng Part A | 2011 Jul | https://www.ncbi.nlm.nih.gov/pubmed/21395444 |
Graphene-based platforms for cancer therapeutics. | Patel SC, Lee S, Lalwani G, Suhrland C, Chowdhury SM, Sitharaman B | Therapeutic delivery | 26769305 | Ther Deliv | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26769305 |
Fabrication and cytocompatibility of in situ crosslinked carbon nanomaterial films. | Patel SC, Lalwani G, Grover K, Qin YX, Sitharaman B | Scientific reports | 26018775 | Sci Rep | 2015 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/26018775 |
In Vitro Bioactivity of One- and Two-Dimensional Nanoparticle-Incorporated Bone Tissue Engineering Scaffolds. | Rashkow JT, Lalwani G, Sitharaman B | Tissue engineering. Part A | 28762866 | Tissue Eng Part A | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/28762866 |
In vitro cytocompatibility of one-dimensional and two-dimensional nanostructure-reinforced biodegradable polymeric nanocomposites. | Farshid B, Lalwani G, Sitharaman B | Journal of biomedical materials research. Part A | 25367032 | J Biomed Mater Res A | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25367032 |
Toxicology of graphene-based nanomaterials. | Lalwani G, D'Agati M, Khan AM, Sitharaman B | Advanced drug delivery reviews | 27154267 | Adv Drug Deliv Rev | 2016 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/27154267 |
Delivery of long chain C(16) and C(24) ceramide in HeLa cells using oxidized graphene nanoribbons. | Suhrland C, Truman JP, Obeid LM, Sitharaman B | Journal of biomedical materials research. Part B, Applied biomaterials | 31444959 | J Biomed Mater Res B Appl Biomater | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31444959 |
Enzymatic Degradation of Oxidized and Reduced Graphene Nanoribbons by Lignin Peroxidase. | Lalwani G, Xing W, Sitharaman B | Journal of materials chemistry. B | 25215188 | J Mater Chem B | 2014 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/25215188 |
Graphene-based contrast agents for photoacoustic and thermoacoustic tomography. | Lalwani G, Cai X, Nie L, Wang LV, Sitharaman B | Photoacoustics | 24490141 | Photoacoustics | 2013 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/24490141 |
Graphene nanoribbons elicit cell specific uptake and delivery via activation of epidermal growth factor receptor enhanced by human papillomavirus E5 protein. | Mullick Chowdhury S, Manepalli P, Sitharaman B | Acta biomaterialia | 24980059 | Acta Biomater | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24980059 |
Synthesis, Characterization, In Vitro Phantom Imaging, and Cytotoxicity of A Novel Graphene-Based Multimodal Magnetic Resonance Imaging - X-Ray Computed Tomography Contrast Agent. | Lalwani G, Sundararaj JL, Schaefer K, Button T, Sitharaman B | Journal of materials chemistry. B | 24999431 | J Mater Chem B | 2014 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/24999431 |
Physicochemical characterization, and relaxometry studies of micro-graphite oxide, graphene nanoplatelets, and nanoribbons. | Paratala BS, Jacobson BD, Kanakia S, Francis LD, Sitharaman B | PloS one | 22685555 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22685555 |
Porous three-dimensional carbon nanotube scaffolds for tissue engineering. | Lalwani G, Gopalan A, D'Agati M, Sankaran JS, Judex S, Qin YX, Sitharaman B | Journal of biomedical materials research. Part A | 25788440 | J Biomed Mater Res A | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25788440 |
Interactions of 1D- and 2D-layered inorganic nanoparticles with fibroblasts and human mesenchymal stem cells. | Rashkow JT, Talukdar Y, Lalwani G, Sitharaman B | Nanomedicine (London, England) | 26080694 | Nanomedicine (Lond) | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26080694 |
Cytotoxicity, cytocompatibility, cell-labeling efficiency, and in vitro cellular magnetic resonance imaging of gadolinium-catalyzed single-walled carbon nanotubes. | Avti PK, Caparelli ED, Sitharaman B | Journal of biomedical materials research. Part A | 23686792 | J Biomed Mater Res A | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23686792 |
Boron nitride nanotubes and nanoplatelets as reinforcing agents of polymeric matrices for bone tissue engineering. | Farshid B, Lalwani G, Shir Mohammadi M, Simonsen J, Sitharaman B | Journal of biomedical materials research. Part B, Applied biomaterials | 26526153 | J Biomed Mater Res B Appl Biomater | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26526153 |
Nanofilm generated non-pharmacological anabolic bone stimulus. | Talukdar Y, Rashkow JT, Patel S, Lalwani G, Bastidas J, Khan S, Sitharaman B | Journal of biomedical materials research. Part A | 31581364 | J Biomed Mater Res A | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31581364 |
Detection, mapping, and quantification of single walled carbon nanotubes in histological specimens with photoacoustic microscopy. | Avti PK, Hu S, Favazza C, Mikos AG, Jansen JA, Shroyer KR, Wang LV, Sitharaman B | PloS one | 22496892 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22496892 |
Multimodal ultrasound-photoacoustic imaging of tissue engineering scaffolds and blood oxygen saturation in and around the scaffolds. | Talukdar Y, Avti P, Sun J, Sitharaman B | Tissue engineering. Part C, Methods | 24107069 | Tissue Eng Part C Methods | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24107069 |
Fabrication and Characterization of Three-Dimensional Macroscopic All-Carbon Scaffolds. | Lalwani G, Kwaczala AT, Kanakia S, Patel SC, Judex S, Sitharaman B | Carbon | 23436939 | Carbon N Y | 2013 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/23436939 |
The magnetic, relaxometric, and optical properties of gadolinium-catalyzed single walled carbon nanotubes. | Sitharaman B, Jacobson BD, Wadghiri YZ, Bryant H, Frank J | Journal of applied physics | 23653487 | J Appl Phys | 2013 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/23653487 |
Tungsten disulfide nanotubes reinforced biodegradable polymers for bone tissue engineering. | Lalwani G, Henslee AM, Farshid B, Parmar P, Lin L, Qin YX, Kasper FK, Mikos AG, Sitharaman B | Acta biomaterialia | 23727293 | Acta Biomater | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23727293 |
Interaction of graphene nanoribbons with components of the blood vascular system. | Chowdhury SM, Fang J, Sitharaman B | Future science OA | 26925250 | Future Sci OA | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26925250 |
Toward single-walled carbon nanotube-gadolinium complex as advanced MRI contrast agents: pharmacodynamics and global genomic response in small animals. | Avti PK, Talukdar Y, Sirotkin MV, Shroyer KR, Sitharaman B | Journal of biomedical materials research. Part B, Applied biomaterials | 23559429 | J Biomed Mater Res B Appl Biomater | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23559429 |
Cell specific cytotoxicity and uptake of graphene nanoribbons. | Mullick Chowdhury S, Lalwani G, Zhang K, Yang JY, Neville K, Sitharaman B | Biomaterials | 23072942 | Biomaterials | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23072942 |
Vasoactive effects of stable aqueous suspensions of single walled carbon nanotubes in hamsters and mice. | Frame MD, Dewar AM, Mullick Chowdhury S, Sitharaman B | Nanotoxicology | 23992463 | Nanotoxicology | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23992463 |
Determination of binding kinetics using whispering gallery mode microcavities. | Soteropulos CE, Hunt HK, Armani AM | Applied physics letters | 21990943 | Appl Phys Lett | 2011 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/21990943 |
Label free detection of 5'hydroxymethylcytosine within CpG islands using optical sensors. | Hawk RM, Armani AM | Biosensors & bioelectronics | 25461158 | Biosens Bioelectron | 2015 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/25461158 |
Temperature sensor based on a hybrid ITO-silica resonant cavity. | Socorro AB, Soltani S, Del Villar I, Corres JM, Armani AM | Optics express | 25836065 | Opt Express | 2015 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/25836065 |
Attaching biological probes to silica optical biosensors using silane coupling agents. | Soteropulos CE, Hunt HK | Journal of visualized experiments : JoVE | 22588224 | J Vis Exp | 2012 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/22588224 |
Selective patterning of Si-based biosensor surfaces using isotropic silicon etchants. | Biggs BW, Hunt HK, Armani AM | Journal of colloid and interface science | 22196345 | J Colloid Interface Sci | 2012 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/22196345 |
Monitoring DNA hybridization using optical microcavities. | Hawk RM, Chistiakova MV, Armani AM | Optics letters | 24322107 | Opt Lett | 2013 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/24322107 |
Titanium-enhanced Raman microcavity laser. | Deka N, Maker AJ, Armani AM | Optics letters | 24690786 | Opt Lett | 2014 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/24690786 |
Nanowatt threshold, alumina sensitized neodymium laser integrated on silicon. | Maker AJ, Armani AM | Optics express | 24216946 | Opt Express | 2013 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/24216946 |
Recycling microcavity optical biosensors. | Hunt HK, Armani AM | Optics letters | 21478993 | Opt Lett | 2011 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/21478993 |
Real-time detection of lipid bilayer assembly and detergent-initiated solubilization using optical cavities. | Sun V, Armani AM | Applied physics letters | 25759510 | Appl Phys Lett | 2015 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/25759510 |
Classifying human brain tumors by lipid imaging with mass spectrometry. | Eberlin LS, Norton I, Dill AL, Golby AJ, Ligon KL, Santagata S, Cooks RG, Agar NY | Cancer research | 22139378 | Cancer Res | 2012 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/22139378 |
Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors. | Eberlin LS, Norton I, Orringer D, Dunn IF, Liu X, Ide JL, Jarmusch AK, Ligon KL, Jolesz FA, Golby AJ, Santagata S, Agar NY, Cooks RG | Proceedings of the National Academy of Sciences of the United States of America | 23300285 | Proc Natl Acad Sci U S A | 2013 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/23300285 |
The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma. | Pokorny JL, Calligaris D, Gupta SK, Iyekegbe DO Jr, Mueller D, Bakken KK, Carlson BL, Schroeder MA, Evans DL, Lou Z, Decker PA, Eckel-Passow JE, Pucci V, Ma B, Shumway SD, Elmquist WF, Agar NY, Sarkaria JN | Clinical cancer research : an official journal of the American Association for Cancer Research | 25609063 | Clin Cancer Res | 2015 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/25609063 |
Reconstruction and Feature Selection for Desorption Electrospray Ionization Mass Spectroscopy Imagery. | Gao Y, Zhu L, Norton I, Agar NY, Tannenbaum A | Proceedings of SPIE--the International Society for Optical Engineering | 25302009 | Proc SPIE Int Soc Opt Eng | 2014 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/25302009 |
Molecular typing of Meningiomas by Desorption Electrospray Ionization Mass Spectrometry Imaging for Surgical Decision-Making. | Calligaris D, Feldman DR, Norton I, Brastianos PK, Dunn IF, Santagata S, Agar NY | International journal of mass spectrometry | 25844057 | Int J Mass Spectrom | 2015 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/25844057 |
First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development. | Jonas O, Calligaris D, Methuku KR, Poe MM, Francois JP, Tranghese F, Changelian A, Sieghart W, Ernst M, Krummel DA, Cook JM, Pomeroy SL, Cima M, Agar NY, Langer R, Sengupta S | Journal of biomedical nanotechnology | 27319222 | J Biomed Nanotechnol | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27319222 |
Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC-ESI-MS-MS. | Kertesz V, Calligaris D, Feldman DR, Changelian A, Laws ER, Santagata S, Agar NY, Van Berkel GJ | Analytical and bioanalytical chemistry | 26084546 | Anal Bioanal Chem | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26084546 |
A statistical modeling approach for tumor-type identification in surgical neuropathology using tissue mass spectrometry imaging. | Gholami B, Norton I, Eberlin LS, Agar NY | IEEE journal of biomedical and health informatics | 24592474 | IEEE J Biomed Health Inform | 2013 May | https://www.ncbi.nlm.nih.gov/pubmed/24592474 |
Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery. | Santagata S, Eberlin LS, Norton I, Calligaris D, Feldman DR, Ide JL, Liu X, Wiley JS, Vestal ML, Ramkissoon SH, Orringer DA, Gill KK, Dunn IF, Dias-Santagata D, Ligon KL, Jolesz FA, Golby AJ, Cooks RG, Agar NY | Proceedings of the National Academy of Sciences of the United States of America | 24982150 | Proc Natl Acad Sci U S A | 2014 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/24982150 |
Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System. | Parrish KE, Cen L, Murray J, Calligaris D, Kizilbash S, Mittapalli RK, Carlson BL, Schroeder MA, Sludden J, Boddy AV, Agar NY, Curtin NJ, Elmquist WF, Sarkaria JN | Molecular cancer therapeutics | 26438157 | Mol Cancer Ther | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26438157 |
Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis. | Calligaris D, Caragacianu D, Liu X, Norton I, Thompson CJ, Richardson AL, Golshan M, Easterling ML, Santagata S, Dillon DA, Jolesz FA, Agar NY | Proceedings of the National Academy of Sciences of the United States of America | 25246570 | Proc Natl Acad Sci U S A | 2014 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/25246570 |
A compressive sensing approach for glioma margin delineation using mass spectrometry. | Gholami B, Agar NY, Jolesz FA, Haddad WM, Tannenbaum AR | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22255629 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22255629 |
Desorption electrospray ionization then MALDI mass spectrometry imaging of lipid and protein distributions in single tissue sections. | Eberlin LS, Liu X, Ferreira CR, Santagata S, Agar NY, Cooks RG | Analytical chemistry | 21975048 | Anal Chem | 2011 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/21975048 |
Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging. | Liu X, Ide JL, Norton I, Marchionni MA, Ebling MC, Wang LY, Davis E, Sauvageot CM, Kesari S, Kellersberger KA, Easterling ML, Santagata S, Stuart DD, Alberta J, Agar JN, Stiles CD, Agar NY | Scientific reports | 24091529 | Sci Rep | 2013 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/24091529 |
Mass spectrometry imaging as a tool for surgical decision-making. | Calligaris D, Norton I, Feldman DR, Ide JL, Dunn IF, Eberlin LS, Cooks RG, Jolesz FA, Golby AJ, Santagata S, Agar NY | Journal of mass spectrometry : JMS | 24259206 | J Mass Spectrom | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24259206 |
Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy. | Ji M, Orringer DA, Freudiger CW, Ramkissoon S, Liu X, Lau D, Golby AJ, Norton I, Hayashi M, Agar NY, Young GS, Spino C, Santagata S, Camelo-Piragua S, Ligon KL, Sagher O, Xie XS | Science translational medicine | 24005159 | Sci Transl Med | 2013 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/24005159 |
Prostate cancer diagnosis and characterization with mass spectrometry imaging. | Kurreck A, Vandergrift LA, Fuss TL, Habbel P, Agar NYR, Cheng LL | Prostate cancer and prostatic diseases | 29209003 | Prostate Cancer Prostatic Dis | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/29209003 |
Recursive feature elimination for brain tumor classification using desorption electrospray ionization mass spectrometry imaging. | Gholami B, Norton I, Tannenbaum AR, Agar NY | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23367115 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23367115 |
Classification of astrocytomas and oligodendrogliomas from mass spectrometry data using sparse kernel machines. | Huang J, Gholami B, Agar NY, Norton I, Haddad WM, Tannenbaum AR | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22256188 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22256188 |
MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation. | Calligaris D, Feldman DR, Norton I, Olubiyi O, Changelian AN, Machaidze R, Vestal ML, Laws ER, Dunn IF, Santagata S, Agar NY | Proceedings of the National Academy of Sciences of the United States of America | 26216958 | Proc Natl Acad Sci U S A | 2015 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/26216958 |
Label-Free Neurosurgical Pathology with Stimulated Raman Imaging. | Lu FK, Calligaris D, Olubiyi OI, Norton I, Yang W, Santagata S, Xie XS, Golby AJ, Agar NY | Cancer research | 27197198 | Cancer Res | 2016 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/27197198 |
Genomics of Loa loa, a Wolbachia-free filarial parasite of humans. | Desjardins CA, Cerqueira GC, Goldberg JM, Dunning Hotopp JC, Haas BJ, Zucker J, Ribeiro JM, Saif S, Levin JZ, Fan L, Zeng Q, Russ C, Wortman JR, Fink DL, Birren BW, Nutman TB | Nature genetics | 23525074 | Nat Genet | 2013 May | https://www.ncbi.nlm.nih.gov/pubmed/23525074 |
Targeted Enrichment and Sequencing of Recent Endosymbiont-Host Lateral Gene Transfers. | Dunning Hotopp JC, Slatko BE, Foster JM | Scientific reports | 28405008 | Sci Rep | 2017 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/28405008 |
Extensive duplication of the Wolbachia DNA in chromosome four of Drosophila ananassae. | Klasson L, Kumar N, Bromley R, Sieber K, Flowers M, Ott SH, Tallon LJ, Andersson SG, Dunning Hotopp JC | BMC genomics | 25496002 | BMC Genomics | 2014 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/25496002 |
Mobile elements and viral integrations prompt considerations for bacterial DNA integration as a novel carcinogen. | Robinson KM, Dunning Hotopp JC | Cancer letters | 24956175 | Cancer Lett | 2014 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/24956175 |
Extensively duplicated and transcriptionally active recent lateral gene transfer from a bacterial Wolbachia endosymbiont to its host filarial nematode Brugia malayi. | Ioannidis P, Johnston KL, Riley DR, Kumar N, White JR, Olarte KT, Ott S, Tallon LJ, Foster JM, Taylor MJ, Dunning Hotopp JC | BMC genomics | 24053607 | BMC Genomics | 2013 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/24053607 |
Modeling the integration of bacterial rRNA fragments into the human cancer genome. | Sieber KB, Gajer P, Dunning Hotopp JC | BMC bioinformatics | 27001685 | BMC Bioinformatics | 2016 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/27001685 |
Lateral gene transfer between prokaryotes and eukaryotes. | Sieber KB, Bromley RE, Dunning Hotopp JC | Experimental cell research | 28189637 | Exp Cell Res | 2017 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/28189637 |
Efficient Enrichment of Bacterial mRNA from Host-Bacteria Total RNA Samples. | Kumar N, Lin M, Zhao X, Ott S, Santana-Cruz I, Daugherty S, Rikihisa Y, Sadzewicz L, Tallon LJ, Fraser CM, Dunning Hotopp JC | Scientific reports | 27713560 | Sci Rep | 2016 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/27713560 |
Biology wars: the eukaryotes strike back. | Dunning Hotopp JC, Estes AM | Cell host & microbe | 25498339 | Cell Host Microbe | 2014 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/25498339 |
A review of bacteria-animal lateral gene transfer may inform our understanding of diseases like cancer. | Robinson KM, Sieber KB, Dunning Hotopp JC | PLoS genetics | 24146634 | PLoS Genet | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24146634 |
Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples. | Riley DR, Sieber KB, Robinson KM, White JR, Ganesan A, Nourbakhsh S, Dunning Hotopp JC | PLoS computational biology | 23840181 | PLoS Comput Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23840181 |
Distinguishing potential bacteria-tumor associations from contamination in a secondary data analysis of public cancer genome sequence data. | Robinson KM, Crabtree J, Mattick JS, Anderson KE, Dunning Hotopp JC | Microbiome | 28118849 | Microbiome | 2017 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/28118849 |
Horizontal gene transfer between bacteria and animals. | Dunning Hotopp JC | Trends in genetics : TIG | 21334091 | Trends Genet | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21334091 |
Single molecule sequencing and genome assembly of a clinical specimen of Loa loa, the causative agent of loiasis. | Tallon LJ, Liu X, Bennuru S, Chibucos MC, Godinez A, Ott S, Zhao X, Sadzewicz L, Fraser CM, Nutman TB, Dunning Hotopp JC | BMC genomics | 25217238 | BMC Genomics | 2014 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/25217238 |
The genome of Onchocerca volvulus, agent of river blindness. | Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, Ribeiro JM, Rogers MB, Stanley E, Swapna LS, Tsai IJ, Unnasch TR, Voronin D, Parkinson J, Nutman TB, Ghedin E, Berriman M, Lustigman S | Nature microbiology | 27869790 | Nat Microbiol | 2016 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/27869790 |
MORC1 represses transposable elements in the mouse male germline. | Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE | Nature communications | 25503965 | Nat Commun | 2014 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/25503965 |
A transgenerational process defines piRNA biogenesis in Drosophila virilis. | Le Thomas A, Marinov GK, Aravin AA | Cell reports | 25199836 | Cell Rep | 2014 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/25199836 |
Production of artificial piRNAs in flies and mice. | Muerdter F, Olovnikov I, Molaro A, Rozhkov NV, Czech B, Gordon A, Hannon GJ, Aravin AA | RNA (New York, N.Y.) | 22096018 | RNA | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22096018 |
MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation. | Manakov SA, Pezic D, Marinov GK, Pastor WA, Sachidanandam R, Aravin AA | Cell reports | 26279574 | Cell Rep | 2015 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/26279574 |
A framework for piRNA cluster manipulation. | Olovnikov I, Le Thomas A, Aravin AA | Methods in molecular biology (Clifton, N.J.) | 24178556 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24178556 |
Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors. | Chen YA, Stuwe E, Luo Y, Ninova M, Le Thomas A, Rozhavskaya E, Li S, Vempati S, Laver JD, Patel DJ, Smibert CA, Lipshitz HD, Toth KF, Aravin AA | Molecular cell | 27292797 | Mol Cell | 2016 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/27292797 |
Prokaryotic Argonautes defend genomes against invasive DNA. | Hur JK, Olovnikov I, Aravin AA | Trends in biochemical sciences | 24836995 | Trends Biochem Sci | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24836995 |
Bacterial argonaute samples the transcriptome to identify foreign DNA. | Olovnikov I, Chan K, Sachidanandam R, Newman DK, Aravin AA | Molecular cell | 24034694 | Mol Cell | 2013 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/24034694 |
Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. | Liu Y, Esyunina D, Olovnikov I, Teplova M, Kulbachinskiy A, Aravin AA, Patel DJ | Cell reports | 29996105 | Cell Rep | 2018 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/29996105 |
Small RNA in the nucleus: the RNA-chromatin ping-pong. | Olovnikov I, Aravin AA, Fejes Toth K | Current opinion in genetics & development | 22349141 | Curr Opin Genet Dev | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22349141 |
Non-Coding RNAs in Transcriptional Regulation: The review for Current Molecular Biology Reports. | Chen YA, Aravin AA | Current molecular biology reports | 26120554 | Curr Mol Biol Rep | 2015 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26120554 |
Small but sturdy: small RNAs in cellular memory and epigenetics. | Stuwe E, Tóth KF, Aravin AA | Genes & development | 24589774 | Genes Dev | 2014 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/24589774 |
Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state. | Le Thomas A, Rogers AK, Webster A, Marinov GK, Liao SE, Perkins EM, Hur JK, Aravin AA, Tóth KF | Genes & development | 23392610 | Genes Dev | 2013 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/23392610 |
Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. | Le Thomas A, Stuwe E, Li S, Du J, Marinov G, Rozhkov N, Chen YC, Luo Y, Sachidanandam R, Toth KF, Patel D, Aravin AA | Genes & development | 25085419 | Genes Dev | 2014 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/25085419 |
To be or not to be a piRNA: genomic origin and processing of piRNAs. | Le Thomas A, Tóth KF, Aravin AA | Genome biology | 24467990 | Genome Biol | 2014 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/24467990 |
piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells. | Pezic D, Manakov SA, Sachidanandam R, Aravin AA | Genes & development | 24939875 | Genes Dev | 2014 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/24939875 |
Splicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila. | Hur JK, Luo Y, Moon S, Ninova M, Marinov GK, Chung YD, Aravin AA | Genes & development | 27036967 | Genes Dev | 2016 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/27036967 |
Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper. | Webster A, Li S, Hur JK, Wachsmuth M, Bois JS, Perkins EM, Patel DJ, Aravin AA | Molecular cell | 26295961 | Mol Cell | 2015 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/26295961 |
Psychiatric blood biomarkers: avoiding jumping to premature negative or positive conclusions. | Niculescu AB, Levey D, Le-Niculescu H, Niculescu E, Kurian SM, Salomon D | Molecular psychiatry | 25582618 | Mol Psychiatry | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25582618 |
Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs. | Niculescu AB, Le-Niculescu H, Roseberry K, Wang S, Hart J, Kaur A, Robertson H, Jones T, Strasburger A, Williams A, Kurian SM, Lamb B, Shekhar A, Lahiri DK, Saykin AJ | Molecular psychiatry | 31792364 | Mol Psychiatry | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31792364 |
Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs. | Le-Niculescu H, Roseberry K, Levey DF, Rogers J, Kosary K, Prabha S, Jones T, Judd S, McCormick MA, Wessel AR, Williams A, Phalen PL, Mamdani F, Sequeira A, Kurian SM, Niculescu AB | Molecular psychiatry | 30862937 | Mol Psychiatry | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/30862937 |
Convergent functional genomics of stem cell-derived cells. | Niculescu AB | Translational psychiatry | 24022510 | Transl Psychiatry | 2013 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/24022510 |
Discovery and validation of blood biomarkers for suicidality. | Le-Niculescu H, Levey DF, Ayalew M, Palmer L, Gavrin LM, Jain N, Winiger E, Bhosrekar S, Shankar G, Radel M, Bellanger E, Duckworth H, Olesek K, Vergo J, Schweitzer R, Yard M, Ballew A, Shekhar A, Sandusky GE, Schork NJ, Kurian SM, Salomon DR, Niculescu AB 3rd | Molecular psychiatry | 23958961 | Mol Psychiatry | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23958961 |
Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. | Ayalew M, Le-Niculescu H, Levey DF, Jain N, Changala B, Patel SD, Winiger E, Breier A, Shekhar A, Amdur R, Koller D, Nurnberger JI, Corvin A, Geyer M, Tsuang MT, Salomon D, Schork NJ, Fanous AH, O'Donovan MC, Niculescu AB | Molecular psychiatry | 22584867 | Mol Psychiatry | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22584867 |
Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms. | Le-Niculescu H, Balaraman Y, Patel SD, Ayalew M, Gupta J, Kuczenski R, Shekhar A, Schork N, Geyer MA, Niculescu AB | Translational psychiatry | 22832404 | Transl Psychiatry | 2011 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/22832404 |
A brief proposal for improving clinical trials. | Niculescu AB | Molecular psychiatry | 27021813 | Mol Psychiatry | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27021813 |
Towards understanding and predicting suicidality in women: biomarkers and clinical risk assessment. | Levey DF, Niculescu EM, Le-Niculescu H, Dainton HL, Phalen PL, Ladd TB, Weber H, Belanger E, Graham DL, Khan FN, Vanipenta NP, Stage EC, Ballew A, Yard M, Gelbart T, Shekhar A, Schork NJ, Kurian SM, Sandusky GE, Salomon DR, Niculescu AB | Molecular psychiatry | 27046645 | Mol Psychiatry | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27046645 |
Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs. | Le-Niculescu H, Roseberry K, Gill SS, Levey DF, Phalen PL, Mullen J, Williams A, Bhairo S, Voegtline T, Davis H, Shekhar A, Kurian SM, Niculescu AB | Molecular psychiatry | 33828235 | Mol Psychiatry | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33828235 |
Genetic risk prediction and neurobiological understanding of alcoholism. | Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Wodarz N, Müller-Myhsok B, Dahmen N, GESGA Consortium, Nöthen M, Sherva R, Farrer L, Smith AH, Kranzler HR, Rietschel M, Gelernter J, Niculescu AB | Translational psychiatry | 24844177 | Transl Psychiatry | 2014 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/24844177 |
Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach. | Niculescu AB, Levey DF, Phalen PL, Le-Niculescu H, Dainton HD, Jain N, Belanger E, James A, George S, Weber H, Graham DL, Schweitzer R, Ladd TB, Learman R, Niculescu EM, Vanipenta NP, Khan FN, Mullen J, Shankar G, Cook S, Humbert C, Ballew A, Yard M, Gelbart T, Shekhar A, Schork NJ, Kurian SM, Sandusky GE, Salomon DR | Molecular psychiatry | 26283638 | Mol Psychiatry | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26283638 |
Precision medicine for suicidality: from universality to subtypes and personalization. | Niculescu AB, Le-Niculescu H, Levey DF, Phalen PL, Dainton HL, Roseberry K, Niculescu EM, Niezer JO, Williams A, Graham DL, Jones TJ, Venugopal V, Ballew A, Yard M, Gelbart T, Kurian SM, Shekhar A, Schork NJ, Sandusky GE, Salomon DR | Molecular psychiatry | 28809398 | Mol Psychiatry | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28809398 |
Convergent functional genomics of psychiatric disorders. | Niculescu AB | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics | 23728881 | Am J Med Genet B Neuropsychiatr Genet | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23728881 |
Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs. | Niculescu AB, Le-Niculescu H, Levey DF, Roseberry K, Soe KC, Rogers J, Khan F, Jones T, Judd S, McCormick MA, Wessel AR, Williams A, Kurian SM, White FA | Molecular psychiatry | 30755720 | Mol Psychiatry | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30755720 |
Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism. | Le-Niculescu H, Case NJ, Hulvershorn L, Patel SD, Bowker D, Gupta J, Bell R, Edenberg HJ, Tsuang MT, Kuczenski R, Geyer MA, Rodd ZA, Niculescu AB | Translational psychiatry | 22832392 | Transl Psychiatry | 2011 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/22832392 |
Dissecting Suicidality Using a Combined Genomic and Clinical Approach. | Niculescu AB, Le-Niculescu H | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 27909331 | Neuropsychopharmacology | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27909331 |
The role of nanomaterials in translational medicine. | Lavik E, von Recum H | ACS nano | 21604811 | ACS Nano | 2011 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/21604811 |
Short term interactions with long term consequences: modulation of chimeric vessels by neural progenitors. | Williams C, Rauch MF, Michaud M, Robinson R, Xu H, Madri J, Lavik E | PloS one | 23300890 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23300890 |
Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: the role of size for intraocular drug delivery. | Robinson R, Viviano SR, Criscione JM, Williams CA, Jun L, Tsai JC, Lavik EB | ACS nano | 21619059 | ACS Nano | 2011 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/21619059 |
Steroid-Loaded Hemostatic Nanoparticles Combat Lung Injury after Blast Trauma. | Hubbard WB, Lashof-Sullivan MM, Lavik EB, VandeVord PJ | ACS macro letters | 27668129 | ACS Macro Lett | 2015 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/27668129 |
Hemostatic Nanoparticles Improve Survival Following Blunt Trauma Even after 1 Week Incubation at 50 (°)C. | Lashof-Sullivan M, Holland M, Groynom R, Campbell D, Shoffstall A, Lavik E | ACS biomaterials science & engineering | 27672679 | ACS Biomater Sci Eng | 2016 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/27672679 |
Intravenously administered nanoparticles increase survival following blast trauma. | Lashof-Sullivan MM, Shoffstall E, Atkins KT, Keane N, Bir C, VandeVord P, Lavik EB | Proceedings of the National Academy of Sciences of the United States of America | 24982180 | Proc Natl Acad Sci U S A | 2014 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/24982180 |
Intravenous hemostats: challenges in translation to patients. | Lashof-Sullivan M, Shoffstall A, Lavik E | Nanoscale | 24088870 | Nanoscale | 2013 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/24088870 |
A hydrogel-endothelial cell implant mimics infantile hemangioma: modulation by survivin and the Hippo pathway. | Tsuneki M, Hardee S, Michaud M, Morotti R, Lavik E, Madri JA | Laboratory investigation; a journal of technical methods and pathology | 25961170 | Lab Invest | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25961170 |
Engineering Intravenously Administered Nanoparticles to Reduce Infusion Reaction and Stop Bleeding in a Large Animal Model of Trauma. | Onwukwe C, Maisha N, Holland M, Varley M, Groynom R, Hickman D, Uppal N, Shoffstall A, Ustin J, Lavik E | Bioconjugate chemistry | 29965731 | Bioconjug Chem | 2018 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/29965731 |
Engineering therapies in the CNS: what works and what can be translated. | Shoffstall AJ, Taylor DM, Lavik EB | Neuroscience letters | 22330751 | Neurosci Lett | 2012 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/22330751 |
Novel drug delivery systems for glaucoma. | Lavik E, Kuehn MH, Kwon YH | Eye (London, England) | 21475311 | Eye (Lond) | 2011 May | https://www.ncbi.nlm.nih.gov/pubmed/21475311 |
Controlled release of photoswitch drugs by degradable polymer microspheres. | Groynom R, Shoffstall E, Wu LS, Kramer RH, Lavik EB | Journal of drug targeting | 26453166 | J Drug Target | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26453166 |
Materials design at the interface of nanoparticles and innate immunity. | Szeto GL, Lavik EB | Journal of materials chemistry. B | 27453783 | J Mater Chem B | 2016 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/27453783 |
Tuning ligand density on intravenous hemostatic nanoparticles dramatically increases survival following blunt trauma. | Shoffstall AJ, Everhart LM, Varley ME, Soehnlen ES, Shick AM, Ustin JS, Lavik EB | Biomacromolecules | 23841817 | Biomacromolecules | 2013 Aug 12 | https://www.ncbi.nlm.nih.gov/pubmed/23841817 |
Intravenous hemostatic nanoparticles increase survival following blunt trauma injury. | Shoffstall AJ, Atkins KT, Groynom RE, Varley ME, Everhart LM, Lashof-Sullivan MM, Martyn-Dow B, Butler RS, Ustin JS, Lavik EB | Biomacromolecules | 22998772 | Biomacromolecules | 2012 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/22998772 |
Olfactory ensheathing cells promote differentiation of neural stem cells and robust neurite extension. | Sethi R, Sethi R, Redmond A, Lavik E | Stem cell reviews and reports | 24996386 | Stem Cell Rev Rep | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24996386 |
Sustained Delivery of Timolol Maleate for Over 90 Days by Subconjunctival Injection. | Lavik E, Kuehn MH, Shoffstall AJ, Atkins K, Dumitrescu AV, Kwon YH | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics | 27835065 | J Ocul Pharmacol Ther | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27835065 |
Examining lethality risk for rodent studies of primary blast lung injury. | Hubbard WB, Hall C, Siva Sai Suijith Sajja V, Lavik E, VandeVord P | Biomedical sciences instrumentation | 25405409 | Biomed Sci Instrum | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25405409 |
Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues. | Wang R, Zheng W, Yu H, Deng H, Luo M | Journal of the American Chemical Society | 21539310 | J Am Chem Soc | 2011 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/21539310 |
A sensitive mass spectrum assay to characterize engineered methionine adenosyltransferases with S-alkyl methionine analogues as substrates. | Wang R, Zheng W, Luo M | Analytical biochemistry | 24374249 | Anal Biochem | 2014 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24374249 |
Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. | Islam K, Chen Y, Wu H, Bothwell IR, Blum GJ, Zeng H, Dong A, Zheng W, Min J, Deng H, Luo M | Proceedings of the National Academy of Sciences of the United States of America | 24082136 | Proc Natl Acad Sci U S A | 2013 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/24082136 |
A high throughput scintillation proximity imaging assay for protein methyltransferases. | Ibanez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, Luo M, Djaballah H | Combinatorial chemistry & high throughput screening | 22256970 | Comb Chem High Throughput Screen | 2012 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/22256970 |
Current chemical biology approaches to interrogate protein methyltransferases. | Luo M | ACS chemical biology | 22220966 | ACS Chem Biol | 2012 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/22220966 |
Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors. | Wang R, Ibáñez G, Islam K, Zheng W, Blum G, Sengelaub C, Luo M | Molecular bioSystems | 21866297 | Mol Biosyst | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21866297 |
Facile synthesis and altered ionization efficiency of diverse Nε-alkyllysine-containing peptides. | Chakraborty D, Islam K, Luo M | Chemical communications (Cambridge, England) | 21959946 | Chem Commun (Camb) | 2012 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/21959946 |
Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling. | Islam K, Zheng W, Yu H, Deng H, Luo M | ACS chemical biology | 21495674 | ACS Chem Biol | 2011 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/21495674 |
A journey toward Bioorthogonal Profiling of Protein Methylation inside living cells. | Wang R, Luo M | Current opinion in chemical biology | 24035694 | Curr Opin Chem Biol | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24035694 |
Small-molecule inhibitors of SETD8 with cellular activity. | Blum G, Ibáñez G, Rao X, Shum D, Radu C, Djaballah H, Rice JC, Luo M | ACS chemical biology | 25137013 | ACS Chem Biol | 2014 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/25137013 |
Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine. | Islam K, Bothwell I, Chen Y, Sengelaub C, Wang R, Deng H, Luo M | Journal of the American Chemical Society | 22404544 | J Am Chem Soc | 2012 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/22404544 |
Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents. | Aldawsari FS, Aguayo-Ortiz R, Kapilashrami K, Yoo J, Luo M, Medina-Franco JL, Velázquez-Martínez CA | Journal of enzyme inhibition and medicinal chemistry | 26118420 | J Enzyme Inhib Med Chem | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26118420 |
Profiling substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues. | Guo H, Wang R, Zheng W, Chen Y, Blum G, Deng H, Luo M | ACS chemical biology | 24320160 | ACS Chem Biol | 2014 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/24320160 |
Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation. | Bothwell IR, Islam K, Chen Y, Zheng W, Blum G, Deng H, Luo M | Journal of the American Chemical Society | 22917021 | J Am Chem Soc | 2012 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/22917021 |
Bioorthogonal profiling of protein methylation (BPPM) using an azido analog of S-adenosyl-L-methionine. | Blum G, Islam K, Luo M | Current protocols in chemical biology | 23667794 | Curr Protoc Chem Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23667794 |
Inhibitors of protein methyltransferases as chemical tools. | Luo M | Epigenomics | 26646500 | Epigenomics | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26646500 |
Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. | Winter JM, Chiou G, Bothwell IR, Xu W, Garg NK, Luo M, Tang Y | Organic letters | 23837609 | Org Lett | 2013 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/23837609 |
Profiling protein methylation with cofactor analog containing terminal alkyne functionality. | Blum G, Bothwell IR, Islam K, Luo M | Current protocols in chemical biology | 23788324 | Curr Protoc Chem Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23788324 |
Profiling genome-wide chromatin methylation with engineered posttranslation apparatus within living cells. | Wang R, Islam K, Liu Y, Zheng W, Tang H, Lailler N, Blum G, Deng H, Luo M | Journal of the American Chemical Society | 23244065 | J Am Chem Soc | 2013 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/23244065 |
Large-scale, protection-free synthesis of Se-adenosyl-L-selenomethionine analogues and their application as cofactor surrogates of methyltransferases. | Bothwell IR, Luo M | Organic letters | 24852128 | Org Lett | 2014 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/24852128 |
Speckle-scale focusing in the diffusive regime with time-reversal of variance-encoded light (TROVE). | Judkewitz B, Wang YM, Horstmeyer R, Mathy A, Yang C | Nature photonics | 23814605 | Nat Photonics | 2013 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/23814605 |
Optical phase conjugation (OPC)-assisted isotropic focusing. | Jang M, Sentenac A, Yang C | Optics express | 23571967 | Opt Express | 2013 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/23571967 |
Analyzing the relationship between decorrelation time and tissue thickness in acute rat brain slices using multispeckle diffusing wave spectroscopy. | Brake J, Jang M, Yang C | Journal of the Optical Society of America. A, Optics, image science, and vision | 26831778 | J Opt Soc Am A Opt Image Sci Vis | 2016 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/26831778 |
Axial standing-wave illumination frequency-domain imaging (SWIF). | Judkewitz B, Yang C | Optics express | 24921798 | Opt Express | 2014 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/24921798 |
Relation between speckle decorrelation and optical phase conjugation (OPC)-based turbidity suppression through dynamic scattering media: a study on in vivo mouse skin. | Jang M, Ruan H, Vellekoop IM, Judkewitz B, Chung E, Yang C | Biomedical optics express | 25657876 | Biomed Opt Express | 2015 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/25657876 |
Model for estimating the penetration depth limit of the time-reversed ultrasonically encoded optical focusing technique. | Jang M, Ruan H, Judkewitz B, Yang C | Optics express | 24663917 | Opt Express | 2014 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/24663917 |
Optical phase conjugation assisted scattering lens: variable focusing and 3D patterning. | Ryu J, Jang M, Eom TJ, Yang C, Chung E | Scientific reports | 27049442 | Sci Rep | 2016 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/27049442 |
Counting White Blood Cells from a Blood Smear Using Fourier Ptychographic Microscopy. | Chung J, Ou X, Kulkarni RP, Yang C | PloS one | 26186353 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26186353 |
Guidestar-assisted wavefront-shaping methods for focusing light into biological tissue. | Horstmeyer R, Ruan H, Yang C | Nature photonics | 27293480 | Nat Photonics | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/27293480 |
Iterative time-reversed ultrasonically encoded light focusing in backscattering mode. | Ruan H, Jang M, Judkewitz B, Yang C | Scientific reports | 25412687 | Sci Rep | 2014 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/25412687 |
Solving ptychography with a convex relaxation. | Horstmeyer R, Chen RY, Ou X, Ames B, Tropp JA, Yang C | New journal of physics | 26146480 | New J Phys | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/26146480 |
Embedded pupil function recovery for Fourier ptychographic microscopy. | Ou X, Zheng G, Yang C | Optics express | 24663835 | Opt Express | 2014 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/24663835 |
Wide-field, high-resolution Fourier ptychographic microscopy. | Zheng G, Horstmeyer R, Yang C | Nature photonics | 25243016 | Nat Photonics | 2013 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/25243016 |
Digital pathology with Fourier ptychography. | Horstmeyer R, Ou X, Zheng G, Willems P, Yang C | Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society | 25481664 | Comput Med Imaging Graph | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25481664 |
Optical focusing inside scattering media with time-reversed ultrasound microbubble encoded light. | Ruan H, Jang M, Yang C | Nature communications | 26597439 | Nat Commun | 2015 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/26597439 |
Overlapped Fourier coding for optical aberration removal. | Horstmeyer R, Ou X, Chung J, Zheng G, Yang C | Optics express | 25321982 | Opt Express | 2014 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/25321982 |
Method for auto-alignment of digital optical phase conjugation systems based on digital propagation. | Jang M, Ruan H, Zhou H, Judkewitz B, Yang C | Optics express | 24977504 | Opt Express | 2014 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/24977504 |
Digital optical phase conjugation of fluorescence in turbid tissue. | Vellekoop IM, Cui M, Yang C | Applied physics letters | 22991478 | Appl Phys Lett | 2012 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/22991478 |
Deep-tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light. | Wang YM, Judkewitz B, Dimarzio CA, Yang C | Nature communications | 22735456 | Nat Commun | 2012 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/22735456 |
A phase space model of Fourier ptychographic microscopy. | Horstmeyer R, Yang C | Optics express | 24514995 | Opt Express | 2014 Jan 13 | https://www.ncbi.nlm.nih.gov/pubmed/24514995 |
Optical Phase Conjugation with Less Than a Photon per Degree of Freedom. | Jang M, Yang C, Vellekoop IM | Physical review letters | 28306287 | Phys Rev Lett | 2017 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/28306287 |
Deep tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light. | Ruan H, Brake J, Robinson JE, Liu Y, Jang M, Xiao C, Zhou C, Gradinaru V, Yang C | Science advances | 29226248 | Sci Adv | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29226248 |
Focusing on moving targets through scattering samples. | Zhou EH, Ruan H, Yang C, Judkewitz B | Optica | 25621302 | Optica | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25621302 |
Focusing through dynamic tissue with millisecond digital optical phase conjugation. | Wang D, Zhou EH, Brake J, Ruan H, Jang M, Yang C | Optica | 26677458 | Optica | 2015 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/26677458 |
Solution structure of a designed cyclic peptide ligand for nickel and copper ions. | Eshelman MR, Aldous AR, Neupane KP, Kritzer JA | Tetrahedron | 25414527 | Tetrahedron | 2014 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/25414527 |
Structured cyclic peptides that bind the EH domain of EHD1. | Kamens AJ, Eisert RJ, Corlin T, Baleja JD, Kritzer JA | Biochemistry | 25014215 | Biochemistry | 2014 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/25014215 |
Comprehensive analysis of loops at protein-protein interfaces for macrocycle design. | Gavenonis J, Sheneman BA, Siegert TR, Eshelman MR, Kritzer JA | Nature chemical biology | 25038791 | Nat Chem Biol | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25038791 |
A bicyclic peptide scaffold promotes phosphotyrosine mimicry and cellular uptake. | Quartararo JS, Eshelman MR, Peraro L, Yu H, Baleja JD, Lin YS, Kritzer JA | Bioorganic & medicinal chemistry | 25438762 | Bioorg Med Chem | 2014 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/25438762 |
Thioether-stapled macrocyclic inhibitors of the EH domain of EHD1. | Kamens AJ, Mientkiewicz KM, Eisert RJ, Walz JA, Mace CR, Kritzer JA | Bioorganic & medicinal chemistry | 28951093 | Bioorg Med Chem | 2018 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/28951093 |
Analysis of Loops that Mediate Protein-Protein Interactions and Translation into Submicromolar Inhibitors. | Siegert TR, Bird MJ, Makwana KM, Kritzer JA | Journal of the American Chemical Society | 27611902 | J Am Chem Soc | 2016 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/27611902 |
Peptide bicycles that inhibit the Grb2 SH2 domain. | Quartararo JS, Wu P, Kritzer JA | Chembiochem : a European journal of chemical biology | 22689355 | Chembiochem | 2012 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/22689355 |
Microchamber integration unifies distinct separation modes for two-dimensional electrophoresis. | Tentori AM, Hughes AJ, Herr AE | Analytical chemistry | 23565932 | Anal Chem | 2013 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/23565932 |
Protein post-translational modification analyses using on-chip immunoprobed isoelectric focusing. | Tia SQ, Brown K, Chen D, Herr AE | Analytical chemistry | 23363036 | Anal Chem | 2013 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/23363036 |
Detection of Isoforms Differing by a Single Charge Unit in Individual Cells. | Tentori AM, Yamauchi KA, Herr AE | Angewandte Chemie (International ed. in English) | 27595864 | Angew Chem Int Ed Engl | 2016 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/27595864 |
Single cell-resolution western blotting. | Kang CC, Yamauchi KA, Vlassakis J, Sinkala E, Duncombe TA, Herr AE | Nature protocols | 27466711 | Nat Protoc | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27466711 |
Chip-based immunoassays. | Apori AA, Herr AE | Methods in molecular biology (Clifton, N.J.) | 22976105 | Methods Mol Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/22976105 |
Microfluidic multiplexing in bioanalyses. | Araz MK, Tentori AM, Herr AE | Journal of laboratory automation | 23757343 | J Lab Autom | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23757343 |
Electrophoretic cytopathology resolves ERBB2 forms with single-cell resolution. | Kang CC, Ward TM, Bockhorn J, Schiffman C, Huang H, Pegram MD, Herr AE | NPJ precision oncology | 29872719 | NPJ Precis Oncol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29872719 |
Single-cell Western blotting after whole-cell imaging to assess cancer chemotherapeutic response. | Kang CC, Lin JM, Xu Z, Kumar S, Herr AE | Analytical chemistry | 25226230 | Anal Chem | 2014 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/25226230 |
Single-cell western blotting. | Hughes AJ, Spelke DP, Xu Z, Kang CC, Schaffer DV, Herr AE | Nature methods | 24880876 | Nat Methods | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24880876 |
Membrane-assisted online renaturation for automated microfluidic lectin blotting. | He M, Novak J, Julian BA, Herr AE | Journal of the American Chemical Society | 22070432 | J Am Chem Soc | 2011 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/22070432 |
Multianalyte on-chip native Western blotting. | Tia SQ, He M, Kim D, Herr AE | Analytical chemistry | 21456518 | Anal Chem | 2011 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/21456518 |
Microfluidics: reframing biological enquiry. | Duncombe TA, Tentori AM, Herr AE | Nature reviews. Molecular cell biology | 26296163 | Nat Rev Mol Cell Biol | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26296163 |
Bistable isoelectric point photoswitching in green fluorescent proteins observed by dynamic immunoprobed isoelectric focusing. | Hughes AJ, Tentori AM, Herr AE | Journal of the American Chemical Society | 23017083 | J Am Chem Soc | 2012 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/23017083 |
Microfluidic Western blotting. | Hughes AJ, Herr AE | Proceedings of the National Academy of Sciences of the United States of America | 23223527 | Proc Natl Acad Sci U S A | 2012 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/23223527 |
Effect of Polymer Hydration State on In-Gel Immunoassays. | Vlassakis J, Herr AE | Analytical chemistry | 26457450 | Anal Chem | 2015 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/26457450 |
Profiling protein expression in circulating tumour cells using microfluidic western blotting. | Sinkala E, Sollier-Christen E, Renier C, Rosàs-Canyelles E, Che J, Heirich K, Duncombe TA, Vlassakis J, Yamauchi KA, Huang H, Jeffrey SS, Herr AE | Nature communications | 28332571 | Nat Commun | 2017 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/28332571 |
Homogeneous immunosubtraction integrated with sample preparation enabled by a microfluidic format. | Apori AA, Herr AE | Analytical chemistry | 21375345 | Anal Chem | 2011 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/21375345 |
Microfluidic integration for automated targeted proteomic assays. | Hughes AJ, Lin RK, Peehl DM, Herr AE | Proceedings of the National Academy of Sciences of the United States of America | 22474344 | Proc Natl Acad Sci U S A | 2012 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/22474344 |
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Microfluidic validation of diagnostic protein markers for spontaneous cerebrospinal fluid rhinorrhea. | Apori AA, Brozynski MN, El-Sayed IH, Herr AE | Journal of proteome research | 23343621 | J Proteome Res | 2013 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/23343621 |
Microfluidic Western blotting of low-molecular-mass proteins. | Gerver RE, Herr AE | Analytical chemistry | 25268977 | Anal Chem | 2014 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/25268977 |
Photopatterned materials in bioanalytical microfluidic technology. | Tentori AM, Herr AE | Journal of micromechanics and microengineering : structures, devices, and systems | 21857772 | J Micromech Microeng | 2011 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/21857772 |
Hydrogel Pore-Size Modulation for Enhanced Single-Cell Western Blotting. | Duncombe TA, Kang CC, Maity S, Ward TM, Pegram MD, Murthy N, Herr AE | Advanced materials (Deerfield Beach, Fla.) | 26567472 | Adv Mater | 2016 Jan 13 | https://www.ncbi.nlm.nih.gov/pubmed/26567472 |
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Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT. | Jungmann R, Avendaño MS, Woehrstein JB, Dai M, Shih WM, Yin P | Nature methods | 24487583 | Nat Methods | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24487583 |
Three-dimensional structures self-assembled from DNA bricks. | Ke Y, Ong LL, Shih WM, Yin P | Science (New York, N.Y.) | 23197527 | Science | 2012 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/23197527 |
Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane. | Werbin JL, Avendaño MS, Becker V, Jungmann R, Yin P, Danuser G, Sorger PK | Scientific reports | 28939861 | Sci Rep | 2017 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/28939861 |
Ribocomputing: Cellular Logic Computation Using RNA Devices. | Kim J, Yin P, Green AA | Biochemistry | 29256603 | Biochemistry | 2018 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/29256603 |
Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA. | Lin C, Jungmann R, Leifer AM, Li C, Levner D, Church GM, Shih WM, Yin P | Nature chemistry | 23000997 | Nat Chem | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23000997 |
Quantitative super-resolution imaging with qPAINT. | Jungmann R, Avendaño MS, Dai M, Woehrstein JB, Agasti SS, Feiger Z, Rodal A, Yin P | Nature methods | 27018580 | Nat Methods | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27018580 |
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes. | Beliveau BJ, Boettiger AN, Avendaño MS, Jungmann R, McCole RB, Joyce EF, Kim-Kiselak C, Bantignies F, Fonseka CY, Erceg J, Hannan MA, Hoang HG, Colognori D, Lee JT, Shih WM, Yin P, Zhuang X, Wu CT | Nature communications | 25962338 | Nat Commun | 2015 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/25962338 |
Sub-100-nm metafluorophores with digitally tunable optical properties self-assembled from DNA. | Woehrstein JB, Strauss MT, Ong LL, Wei B, Zhang DY, Jungmann R, Yin P | Science advances | 28691083 | Sci Adv | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28691083 |
Super-resolution Geometric Barcoding for Multiplexed miRNA Profiling. | Xu W, Yin P, Dai M | Angewandte Chemie (International ed. in English) | 30182521 | Angew Chem Int Ed Engl | 2018 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/30182521 |
Optimizing the specificity of nucleic acid hybridization. | Zhang DY, Chen SX, Yin P | Nature chemistry | 22354435 | Nat Chem | 2012 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/22354435 |
Casting inorganic structures with DNA molds. | Sun W, Boulais E, Hakobyan Y, Wang WL, Guan A, Bathe M, Yin P | Science (New York, N.Y.) | 25301973 | Science | 2014 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/25301973 |
Complex reconfiguration of DNA nanostructures. | Wei B, Ong LL, Chen J, Jaffe AS, Yin P | Angewandte Chemie (International ed. in English) | 24899518 | Angew Chem Int Ed Engl | 2014 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/24899518 |
The emerging landscape of single-molecule protein sequencing technologies. | Alfaro JA, Bohländer P, Dai M, Filius M, Howard CJ, van Kooten XF, Ohayon S, Pomorski A, Schmid S, Aksimentiev A, Anslyn EV, Bedran G, Cao C, Chinappi M, Coyaud E, Dekker C, Dittmar G, Drachman N, Eelkema R, Goodlett D, Hentz S, Kalathiya U, Kelleher NL, Kelly RT, Kelman Z, Kim SH, Kuster B, Rodriguez-Larrea D, Lindsay S, Maglia G, Marcotte EM, Marino JP, Masselon C, Mayer M, Samaras P, Sarthak K, Sepiashvili L, Stein D, Wanunu M, Wilhelm M, Yin P, Meller A, Joo C | Nature methods | 34099939 | Nat Methods | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34099939 |
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Informing brain connectivity with optogenetic functional magnetic resonance imaging. | Lee JH | NeuroImage | 22326987 | Neuroimage | 2012 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/22326987 |
High spatial resolution compressed sensing (HSPARSE) functional MRI. | Fang Z, Van Le N, Choy M, Lee JH | Magnetic resonance in medicine | 26511101 | Magn Reson Med | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26511101 |
MRI compatible optrodes for simultaneous LFP and optogenetic fMRI investigation of seizure-like afterdischarges. | Duffy BA, Choy M, Chuapoco MR, Madsen M, Lee JH | NeuroImage | 26208873 | Neuroimage | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26208873 |
Silicon coupled with plasmon nanocavity generates bright visible hot-luminescence. | Cho CH, Aspetti CO, Park J, Agarwal R | Nature photonics | 23710256 | Nat Photonics | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23710256 |
Enhanced second-harmonic generation from metal-integrated semiconductor nanowires via highly confined whispering gallery modes. | Ren ML, Liu W, Aspetti CO, Sun L, Agarwal R | Nature communications | 25388766 | Nat Commun | 2014 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/25388766 |
Tailoring light-matter coupling in semiconductor and hybrid-plasmonic nanowires. | Piccione B, Aspetti CO, Cho CH, Agarwal R | Reports on progress in physics. Physical Society (Great Britain) | 25093385 | Rep Prog Phys | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/25093385 |
Studies of hot photoluminescence in plasmonically coupled silicon via variable energy excitation and temperature-dependent spectroscopy. | Aspetti CO, Cho CH, Agarwal R, Agarwal R | Nano letters | 25120156 | Nano Lett | 2014 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/25120156 |
Size-dependent chemical transformation, structural phase-change, and optical properties of nanowires. | Piccione B, Agarwal R, Jung Y, Agarwal R | Philosophical magazine (Abingdon, England) | 23997656 | Philos Mag (Abingdon) | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23997656 |
Strain-induced large exciton energy shifts in buckled CdS nanowires. | Sun L, Kim DH, Oh KH, Agarwal R | Nano letters | 23899018 | Nano Lett | 2013 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/23899018 |
Redox-Responsive, Core Cross-Linked Polyester Micelles. | Zhang Z, Yin L, Tu C, Song Z, Zhang Y, Xu Y, Tong R, Zhou Q, Ren J, Cheng J | ACS macro letters | 23536920 | ACS Macro Lett | 2013 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/23536920 |
Drug-Initiated, Controlled Ring-Opening Polymerization for the Synthesis of Polymer-Drug Conjugates. | Tong R, Cheng J | Macromolecules | 23357880 | Macromolecules | 2012 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/23357880 |
Non-invasive, real-time reporting drug release in vitro and in vivo. | Zhang Y, Yin Q, Yen J, Li J, Ying H, Wang H, Hua Y, Chaney EJ, Boppart SA, Cheng J | Chemical communications (Cambridge, England) | 25798457 | Chem Commun (Camb) | 2015 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/25798457 |
CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells. | Myers DE, Yiv S, Qazi S, Ma H, Cely I, Shahidzadeh A, Arellano M, Finestone E, Gaynon PS, Termuhlen A, Cheng J, Uckun FM | Integrative biology : quantitative biosciences from nano to macro | 24910947 | Integr Biol (Camb) | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24910947 |
Redox-responsive, reversibly-crosslinked thiolated cationic helical polypeptides for efficient siRNA encapsulation and delivery. | Zheng N, Song Z, Liu Y, Zhang R, Zhang R, Yao C, Uckun FM, Yin L, Cheng J | Journal of controlled release : official journal of the Controlled Release Society | 25683619 | J Control Release | 2015 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/25683619 |
Investigating the optimal size of anticancer nanomedicine. | Tang L, Yang X, Yin Q, Cai K, Wang H, Chaudhury I, Yao C, Zhou Q, Kwon M, Hartman JA, Dobrucki IT, Dobrucki LW, Borst LB, Lezmi S, Helferich WG, Ferguson AL, Fan TM, Cheng J | Proceedings of the National Academy of Sciences of the United States of America | 25316794 | Proc Natl Acad Sci U S A | 2014 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/25316794 |
Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cells. | Yen J, Zhang Y, Gabrielson NP, Yin L, Guan L, Chaudhury I, Lu H, Wang F, Cheng J | Biomaterials science | 23997932 | Biomater Sci | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23997932 |
Polypeptides with quaternary phosphonium side chains: synthesis, characterization, and cell-penetrating properties. | Song Z, Zheng N, Ba X, Yin L, Zhang R, Ma L, Cheng J | Biomacromolecules | 24635536 | Biomacromolecules | 2014 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/24635536 |
Water-soluble poly(L-serine)s with elongated and charged side-chains: synthesis, conformations, and cell-penetrating properties. | Tang H, Yin L, Lu H, Cheng J | Biomacromolecules | 22853191 | Biomacromolecules | 2012 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/22853191 |
Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A. | Tang L, Azzi J, Kwon M, Mounayar M, Tong R, Yin Q, Moore R, Skartsis N, Fan TM, Abdi R, Cheng J | Journal of transplantation | 22545201 | J Transplant | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22545201 |
Design of Albumin-Coated Microbubbles Loaded With Polylactide Nanoparticles. | Gauthier M, Yin Q, Cheng J, O'Brien WD Jr | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine | 26206822 | J Ultrasound Med | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26206822 |
Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-Site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-Precursor Leukemia and Yield Superior Survival Outcomes in Mice. | Uckun FM, Myers DE, Cheng J, Qazi S | EBioMedicine | 26285772 | EBioMedicine | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26285772 |
Poly(iohexol) nanoparticles as contrast agents for in vivo X-ray computed tomography imaging. | Yin Q, Yap FY, Yin L, Ma L, Zhou Q, Dobrucki LW, Fan TM, Gaba RC, Cheng J | Journal of the American Chemical Society | 23987119 | J Am Chem Soc | 2013 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/23987119 |
PEG-Polypeptide Dual Brush Block Copolymers: Synthesis and Application in Nanoparticle Surface PEGylation. | Zhang Y, Yin Q, Lu H, Xia H, Lin Y, Cheng J | ACS macro letters | 24159425 | ACS Macro Lett | 2013 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/24159425 |
Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting. | Zheng N, Yin L, Song Z, Ma L, Tang H, Gabrielson NP, Lu H, Cheng J | Biomaterials | 24211080 | Biomaterials | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24211080 |
Dimeric drug polymeric nanoparticles with exceptionally high drug loading and quantitative loading efficiency. | Cai K, He X, Song Z, Yin Q, Zhang Y, Uckun FM, Jiang C, Cheng J | Journal of the American Chemical Society | 25741752 | J Am Chem Soc | 2015 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/25741752 |
Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics. | Cai K, Yen J, Yin Q, Liu Y, Song Z, Lezmi S, Zhang Y, Yang X, Helferich WG, Cheng J | Biomaterials science | 26146551 | Biomater Sci | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26146551 |
In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates. | Wang H, Tang L, Liu Y, Dobrucka IT, Dobrucki LW, Yin L, Cheng J | Theranostics | 27375793 | Theranostics | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27375793 |
Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultra-Stable Helical Conformations. | Zhang Y, Lu H, Lin Y, Cheng J | Macromolecules | 22049249 | Macromolecules | 2011 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/22049249 |
Ring-Opening Polymerization of γ-(4-Vinylbenzyl)-(L)-Glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides. | Lu H, Bai Y, Wang J, Gabrielson NP, Wang F, Lin Y, Cheng J | Macromolecules | 22121300 | Macromolecules | 2011 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/22121300 |
Dynamic urea bond for the design of reversible and self-healing polymers. | Ying H, Zhang Y, Cheng J | Nature communications | 24492620 | Nat Commun | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24492620 |
The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides. | Zhang R, Zheng N, Song Z, Yin L, Cheng J | Biomaterials | 24439403 | Biomaterials | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24439403 |
Targeted Ultrasound-Assisted Cancer-Selective Chemical Labeling and Subsequent Cancer Imaging using Click Chemistry. | Wang H, Gauthier M, Kelly JR, Miller RJ, Xu M, O'Brien WD Jr, Cheng J | Angewandte Chemie (International ed. in English) | 27010510 | Angew Chem Int Ed Engl | 2016 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/27010510 |
Selective in vivo metabolic cell-labeling-mediated cancer targeting. | Wang H, Wang R, Cai K, He H, Liu Y, Yen J, Wang Z, Xu M, Sun Y, Zhou X, Yin Q, Tang L, Dobrucki IT, Dobrucki LW, Chaney EJ, Boppart SA, Fan TM, Lezmi S, Chen X, Yin L, Cheng J | Nature chemical biology | 28192414 | Nat Chem Biol | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/28192414 |
Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates. | Tang L, Gabrielson NP, Uckun FM, Fan TM, Cheng J | Molecular pharmaceutics | 23301497 | Mol Pharm | 2013 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/23301497 |
Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles. | Cely I, Yiv S, Yin Q, Shahidzadeh A, Tang L, Cheng J, Uckun FM | Journal of analytical oncology | 23730399 | J Anal Oncol | 2012 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/23730399 |
Polymeric Nanomedicines Based on Poly(lactide) and Poly(lactide-co-glycolide). | Tong R, Gabrielson NP, Fan TM, Cheng J | Current opinion in solid state & materials science | 23914135 | Curr Opin Solid State Mater Sci | 2012 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/23914135 |
Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery. | Yin L, Song Z, Kim KH, Zheng N, Tang H, Lu H, Gabrielson N, Cheng J | Biomaterials | 23283350 | Biomaterials | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23283350 |
Non-viral gene delivery via membrane-penetrating, mannose-targeting supramolecular self-assembled nanocomplexes. | Yin L, Song Z, Kim KH, Zheng N, Gabrielson NP, Cheng J | Advanced materials (Deerfield Beach, Fla.) | 23417835 | Adv Mater | 2013 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/23417835 |
Trigger-responsive, fast-degradable poly(β-amino ester)s for enhanced DNA unpackaging and reduced toxicity. | Deng X, Zheng N, Song Z, Yin L, Cheng J | Biomaterials | 24674461 | Biomaterials | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24674461 |
Redox-responsive, core-cross-linked micelles capable of on-demand, concurrent drug release and structure disassembly. | Wang H, Tang L, Tu C, Song Z, Yin Q, Yin L, Zhang Z, Cheng J | Biomacromolecules | 24003893 | Biomacromolecules | 2013 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/24003893 |
CD22ΔE12 as a molecular target for RNAi therapy. | Uckun FM, Ma H, Cheng J, Myers DE, Qazi S | British journal of haematology | 25659406 | Br J Haematol | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25659406 |
Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo. | Xing H, Tang L, Yang X, Hwang K, Wang W, Yin Q, Wong NY, Dobrucki LW, Yasui N, Katzenellenbogen JA, Helferich WG, Cheng J, Lu Y | Journal of materials chemistry. B | 24159374 | J Mater Chem B | 2013 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/24159374 |
Helical Poly(arginine) Mimics with Superior Cell-Penetrating and Molecular Transporting Properties. | Tang H, Yin L, Kim KH, Cheng J | Chemical science | 25400902 | Chem Sci | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25400902 |
Hydrolyzable polyureas bearing hindered urea bonds. | Ying H, Cheng J | Journal of the American Chemical Society | 25406025 | J Am Chem Soc | 2014 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/25406025 |
A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies. | Uckun FM, Qazi S, Ma H, Yin L, Cheng J | EBioMedicine | 25599086 | EBioMedicine | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25599086 |
Reactive and bioactive cationic α-helical polypeptide template for nonviral gene delivery. | Gabrielson NP, Lu H, Yin L, Li D, Wang F, Cheng J | Angewandte Chemie (International ed. in English) | 22162307 | Angew Chem Int Ed Engl | 2012 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/22162307 |
Enhanced Non-Viral Gene Delivery to Human Embryonic Stem Cells via Small Molecule-Mediated Transient Alteration of Cell Structure. | Yen J, Yin L, Cheng J | Journal of materials chemistry. B | 26005572 | J Mater Chem B | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/26005572 |
Targeting tumor vasculature with aptamer-functionalized doxorubicin-polylactide nanoconjugates for enhanced cancer therapy. | Tang L, Tong R, Coyle VJ, Yin Q, Pondenis H, Borst LB, Cheng J, Fan TM | ACS nano | 25938427 | ACS Nano | 2015 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/25938427 |
Targeting leukemic stem cells with multifunctional bioactive polypeptide nanoparticles. | Uckun FM, Qazi S, Cheng J | Future oncology (London, England) | 25832872 | Future Oncol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25832872 |
Development of Polypeptide-based Nanoparticles for Non-viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL. | Uckun FM, Mitchell LG, Qazi S, Liu Y, Zheng N, Myers DE, Song Z, Ma H, Cheng J | EBioMedicine | 26288837 | EBioMedicine | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26288837 |
Facile functionalization of polyesters through thiol-yne chemistry for the design of degradable, cell-penetrating and gene delivery dual-functional agents. | Zhang Z, Yin L, Xu Y, Tong R, Lu Y, Ren J, Cheng J | Biomacromolecules | 23098261 | Biomacromolecules | 2012 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/23098261 |
Polyvalent mesoporous silica nanoparticle-aptamer bioconjugates target breast cancer cells. | Li LL, Yin Q, Cheng J, Lu Y | Advanced healthcare materials | 23184791 | Adv Healthc Mater | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23184791 |
Synthesis of water-soluble poly(α-hydroxy acids) from living ring-opening polymerization of O-benzyl-L-serine carboxyanhydrides. | Lu Y, Yin L, Zhang Y, Zhonghai Z, Xu Y, Tong R, Cheng J | ACS macro letters | 23359651 | ACS Macro Lett | 2012 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/23359651 |
Manipulating the membrane penetration mechanism of helical polypeptides via aromatic modification for efficient gene delivery. | Zheng N, Song Z, Yang J, Liu Y, Li F, Cheng J, Yin L | Acta biomaterialia | 28476586 | Acta Biomater | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28476586 |
Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation. | Yin L, Song Z, Qu Q, Kim KH, Zheng N, Yao C, Chaudhury I, Tang H, Gabrielson NP, Uckun FM, Cheng J | Angewandte Chemie (International ed. in English) | 23610013 | Angew Chem Int Ed Engl | 2013 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/23610013 |
Chain-shattering polymeric therapeutics with on-demand drug-release capability. | Zhang Y, Yin Q, Yin L, Ma L, Tang L, Cheng J | Angewandte Chemie (International ed. in English) | 23650111 | Angew Chem Int Ed Engl | 2013 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/23650111 |
Nonporous Silica Nanoparticles for Nanomedicine Application. | Tang L, Cheng J | Nano today | 23997809 | Nano Today | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23997809 |
Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis. | Yin Q, Tang L, Cai K, Tong R, Sternberg R, Yang X, Dobrucki LW, Borst LB, Kamstock D, Song Z, Helferich WG, Cheng J, Fan TM | Proceedings of the National Academy of Sciences of the United States of America | 27457945 | Proc Natl Acad Sci U S A | 2016 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/27457945 |
In vivo cancer targeting via glycopolyester nanoparticle mediated metabolic cell labeling followed by click reaction. | Wang H, Bo Y, Liu Y, Xu M, Cai K, Wang R, Cheng J | Biomaterials | 31323538 | Biomaterials | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31323538 |
Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia. | Uckun FM, Qazi S, Cely I, Sahin K, Shahidzadeh A, Ozercan I, Yin Q, Gaynon P, Termuhlen A, Cheng J, Yiv S | Blood | 23568490 | Blood | 2013 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/23568490 |
Drug-initiated ring-opening polymerization of O-carboxyanhydrides for the preparation of anticancer drug-poly(O-carboxyanhydride) nanoconjugates. | Yin Q, Tong R, Xu Y, Baek K, Dobrucki LW, Fan TM, Cheng J | Biomacromolecules | 23445497 | Biomacromolecules | 2013 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/23445497 |
Light-responsive helical polypeptides capable of reducing toxicity and unpacking DNA: toward nonviral gene delivery. | Yin L, Tang H, Kim KH, Zheng N, Song Z, Gabrielson NP, Lu H, Cheng J | Angewandte Chemie (International ed. in English) | 23832670 | Angew Chem Int Ed Engl | 2013 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/23832670 |
A cell-penetrating helical polymer for siRNA delivery to mammalian cells. | Gabrielson NP, Lu H, Yin L, Kim KH, Cheng J | Molecular therapy : the journal of the American Society of Gene Therapy | 22643866 | Mol Ther | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22643866 |
Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates. | Tang L, Fan TM, Borst LB, Cheng J | ACS nano | 22494403 | ACS Nano | 2012 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/22494403 |
Ionic polypeptides with unusual helical stability. | Lu H, Wang J, Bai Y, Lang JW, Liu S, Lin Y, Cheng J | Nature communications | 21343924 | Nat Commun | 2011 Feb 22 | https://www.ncbi.nlm.nih.gov/pubmed/21343924 |
Helical antimicrobial polypeptides with radial amphiphilicity. | Xiong M, Lee MW, Mansbach RA, Song Z, Bao Y, Peek RM Jr, Yao C, Chen LF, Ferguson AL, Wong GC, Cheng J | Proceedings of the National Academy of Sciences of the United States of America | 26460016 | Proc Natl Acad Sci U S A | 2015 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/26460016 |
Ionic α-helical polypeptides toward nonviral gene delivery. | Zhang R, Song Z, Yin L, Zheng N, Tang H, Lu H, Gabrielson NP, Lin Y, Kim K, Cheng J | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 25377262 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2015 Jan-Feb | https://www.ncbi.nlm.nih.gov/pubmed/25377262 |
Synthesis of hybrid block copolymers via integrated ring-opening metathesis polymerization and polymerization of NCA. | Bai Y, Lu H, Ponnusamy E, Cheng J | Chemical communications (Cambridge, England) | 21869956 | Chem Commun (Camb) | 2011 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/21869956 |
Anticancer Camptothecin-N-Poly(lactic acid) Nanoconjugates with Facile Hydrolysable Linker. | Yin Q, Tong R, Yin L, Fan TM, Cheng J | Polymer chemistry | 26005498 | Polym Chem | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/26005498 |
Dual Stimuli-Responsive Poly(β-amino ester) Nanoparticles for On-Demand Burst Release. | Lee JS, Deng X, Han P, Cheng J | Macromolecular bioscience | 26036966 | Macromol Biosci | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26036966 |
Bioorthogonal Oxime Ligation Mediated In Vivo Cancer Targeting. | Tang L, Yin Q, Xu Y, Zhou Q, Cai K, Yen J, Dobrucki LW, Cheng J | Chemical science | 26146536 | Chem Sci | 2015 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/26146536 |
Synthesis and biomedical applications of functional poly(α-hydroxy acids) via ring-opening polymerization of O-carboxyanhydrides. | Yin Q, Yin L, Wang H, Cheng J | Accounts of chemical research | 26065588 | Acc Chem Res | 2015 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/26065588 |
Biodegradable micelles capable of mannose-mediated targeted drug delivery to cancer cells. | Yin L, Chen Y, Zhang Z, Yin Q, Zheng N, Cheng J | Macromolecular rapid communications | 25619623 | Macromol Rapid Commun | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25619623 |
Reduction-responsive dithiomaleimide-based nanomedicine with high drug loading and FRET-indicated drug release. | Wang H, Xu M, Xiong M, Cheng J | Chemical communications (Cambridge, England) | 25692778 | Chem Commun (Camb) | 2015 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/25692778 |
Molecular simulations of aromatase reveal new insights into the mechanism of ligand binding. | Park J, Czapla L, Amaro RE | Journal of chemical information and modeling | 23927370 | J Chem Inf Model | 2013 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/23927370 |
The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution. | Rathore A, Carpenter MA, Demir Ö, Ikeda T, Li M, Shaban NM, Law EK, Anokhin D, Brown WL, Amaro RE, Harris RS | Journal of molecular biology | 23938202 | J Mol Biol | 2013 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/23938202 |
Designing novel inhibitors of Trypanosoma brucei. | Demir O, Amaro RE | Methods in molecular biology (Clifton, N.J.) | 23568474 | Methods Mol Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23568474 |
Electrostatic Interactions as Mediators in the Allosteric Activation of Protein Kinase A RIα. | P Barros E, Malmstrom RD, Nourbakhsh K, Del Rio JC, Kornev AP, Taylor SS, Amaro RE | Biochemistry | 28221775 | Biochemistry | 2017 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/28221775 |
WebChem Viewer: a tool for the easy dissemination of chemical and structural data sets. | Durrant JD, Amaro RE | BMC bioinformatics | 24886360 | BMC Bioinformatics | 2014 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/24886360 |
Mesoscale All-Atom Influenza Virus Simulations Suggest New Substrate Binding Mechanism. | Durrant JD, Kochanek SE, Casalino L, Ieong PU, Dommer AC, Amaro RE | ACS central science | 32123736 | ACS Cent Sci | 2020 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/32123736 |
The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release. | Bohl HO, Ieong P, Lee JK, Lee T, Kankanala J, Shi K, Demir Ö, Kurahashi K, Amaro RE, Wang Z, Aihara H | The Journal of biological chemistry | 29626094 | J Biol Chem | 2018 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/29626094 |
A novel high-throughput activity assay for the Trypanosoma brucei editosome enzyme REL1 and other RNA ligases. | Zimmermann S, Hall L, Riley S, Sørensen J, Amaro RE, Schnaufer A | Nucleic acids research | 26400159 | Nucleic Acids Res | 2016 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/26400159 |
The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches. | Richards C, Albin JS, Demir Ö, Shaban NM, Luengas EM, Land AM, Anderson BD, Holten JR, Anderson JS, Harki DA, Amaro RE, Harris RS | Cell reports | 26628363 | Cell Rep | 2015 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/26628363 |
Structural characterisation of Tpx from Yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds. | Gabrielsen M, Beckham KS, Feher VA, Zetterström CE, Wang D, Müller S, Elofsson M, Amaro RE, Byron O, Roe AJ | PloS one | 22384182 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22384182 |
Rational prediction with molecular dynamics for hit identification. | Nichols SE, Swift RV, Amaro RE | Current topics in medicinal chemistry | 23110535 | Curr Top Med Chem | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23110535 |
Molecular-level simulation of pandemic influenza glycoproteins. | Amaro RE, Li WW | Methods in molecular biology (Clifton, N.J.) | 22183559 | Methods Mol Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22183559 |
Microsecond Molecular Dynamics Simulations of Influenza Neuraminidase Suggest a Mechanism for the Increased Virulence of Stalk-Deletion Mutants. | Durrant JD, Bush RM, Amaro RE | The journal of physical chemistry. B | 27141956 | J Phys Chem B | 2016 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/27141956 |
Multiscale Estimation of Binding Kinetics Using Brownian Dynamics, Molecular Dynamics and Milestoning. | Votapka LW, Amaro RE | PLoS computational biology | 26505480 | PLoS Comput Biol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26505480 |
Bridging scales through multiscale modeling: a case study on protein kinase A. | Boras BW, Hirakis SP, Votapka LW, Malmstrom RD, Amaro RE, McCulloch AD | Frontiers in physiology | 26441670 | Front Physiol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26441670 |
Efficient Calculation of Accurate Reaction Energies-Assessment of Different Models in Electronic Structure Theory. | Friedrich J | Journal of chemical theory and computation | 26574443 | J Chem Theory Comput | 2015 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/26574443 |
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B. | Shi K, Carpenter MA, Banerjee S, Shaban NM, Kurahashi K, Salamango DJ, McCann JL, Starrett GJ, Duffy JV, Demir Ö, Amaro RE, Harki DA, Harris RS, Aihara H | Nature structural & molecular biology | 27991903 | Nat Struct Mol Biol | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/27991903 |
Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit. | Mulero MC, Shahabi S, Ko MS, Schiffer JM, Huang DB, Wang VY, Amaro RE, Huxford T, Ghosh G | Biochemistry | 29708732 | Biochemistry | 2018 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/29708732 |
Modeling the pharmacodynamics of passive membrane permeability. | Swift RV, Amaro RE | Journal of computer-aided molecular design | 22042376 | J Comput Aided Mol Des | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/22042376 |
Mechanism of 150-cavity formation in influenza neuraminidase. | Amaro RE, Swift RV, Votapka L, Li WW, Walker RC, Bush RM | Nature communications | 21750542 | Nat Commun | 2011 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/21750542 |
Machine-learning techniques applied to antibacterial drug discovery. | Durrant JD, Amaro RE | Chemical biology & drug design | 25521642 | Chem Biol Drug Des | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25521642 |
Enhancing Virtual Screening Performance of Protein Kinases with Molecular Dynamics Simulations. | Offutt TL, Swift RV, Amaro RE | Journal of chemical information and modeling | 27662181 | J Chem Inf Model | 2016 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/27662181 |
POVME 3.0: Software for Mapping Binding Pocket Flexibility. | Wagner JR, Sørensen J, Hensley N, Wong C, Zhu C, Perison T, Amaro RE | Journal of chemical theory and computation | 28800393 | J Chem Theory Comput | 2017 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/28800393 |
Capturing Invisible Motions in the Transition from Ground to Rare Excited States of T4 Lysozyme L99A. | Schiffer JM, Feher VA, Malmstrom RD, Sida R, Amaro RE | Biophysical journal | 27760351 | Biophys J | 2016 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/27760351 |
Multistructural hot spot characterization with FTProd. | Votapka L, Amaro RE | Bioinformatics (Oxford, England) | 23202744 | Bioinformatics | 2013 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/23202744 |
Exploring residue component contributions to dynamical network models of allostery. | Vanwart AT, Eargle J, Luthey-Schulten Z, Amaro RE | Journal of chemical theory and computation | 23139645 | J Chem Theory Comput | 2012 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/23139645 |
A 3-dimensional trimeric β-barrel model for Chlamydia MOMP contains conserved and novel elements of Gram-negative bacterial porins. | Feher VA, Randall A, Baldi P, Bush RM, de la Maza LM, Amaro RE | PloS one | 23935908 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23935908 |
Molecular docking to flexible targets. | Sørensen J, Demir Ö, Swift RV, Feher VA, Amaro RE | Methods in molecular biology (Clifton, N.J.) | 25330975 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25330975 |
Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester. | Castro-Falcón G, Seiler GS, Demir Ö, Rathinaswamy MK, Hamelin D, Hoffmann RM, Makowski SL, Letzel AC, Field SJ, Burke JE, Amaro RE, Hughes CC | Journal of medicinal chemistry | 30380865 | J Med Chem | 2018 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/30380865 |
Structural basis for ligand modulation of the CCR2 conformational landscape. | Taylor BC, Lee CT, Amaro RE | Proceedings of the National Academy of Sciences of the United States of America | 30975755 | Proc Natl Acad Sci U S A | 2019 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/30975755 |
Allostery through the computational microscope: cAMP activation of a canonical signalling domain. | Malmstrom RD, Kornev AP, Taylor SS, Amaro RE | Nature communications | 26145448 | Nat Commun | 2015 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/26145448 |
Quantitative Ranking of Ligand Binding Kinetics with a Multiscale Milestoning Simulation Approach. | Jagger BR, Lee CT, Amaro RE | The journal of physical chemistry letters | 30070844 | J Phys Chem Lett | 2018 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/30070844 |
Multiscale Methods in Drug Design Bridge Chemical and Biological Complexity in the Search for Cures. | Amaro RE, Mulholland AJ | Nature reviews. Chemistry | 30949587 | Nat Rev Chem | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30949587 |
On the Application of Molecular-Dynamics Based Markov State Models to Functional Proteins. | Malmstrom RD, Lee CT, Van Wart A, Amaro RE | Journal of chemical theory and computation | 25473382 | J Chem Theory Comput | 2014 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/25473382 |
A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity. | Ikram NK, Durrant JD, Muchtaridi M, Zalaludin AS, Purwitasari N, Mohamed N, Rahim AS, Lam CK, Normi YM, Rahman NA, Amaro RE, Wahab HA | Journal of chemical information and modeling | 25555059 | J Chem Inf Model | 2015 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/25555059 |
Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants. | Demir Ö, Baronio R, Salehi F, Wassman CD, Hall L, Hatfield GW, Chamberlin R, Kaiser P, Lathrop RH, Amaro RE | PLoS computational biology | 22028641 | PLoS Comput Biol | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22028641 |
Molecular dynamics analysis of antibody recognition and escape by human H1N1 influenza hemagglutinin. | Ieong P, Amaro RE, Li WW | Biophysical journal | 26039171 | Biophys J | 2015 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/26039171 |
Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands. | Durrant JD, Carlson KE, Martin TA, Offutt TL, Mayne CG, Katzenellenbogen JA, Amaro RE | Journal of chemical information and modeling | 26286148 | J Chem Inf Model | 2015 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/26286148 |
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53. | Wassman CD, Baronio R, Demir Ö, Wallentine BD, Chen CK, Hall LV, Salehi F, Lin DW, Chung BP, Hatfield GW, Richard Chamberlin A, Luecke H, Lathrop RH, Kaiser P, Amaro RE | Nature communications | 23360998 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23360998 |
Magnesium-induced nucleophile activation in the guanylyltransferase mRNA capping enzyme. | Swift RV, Ong CD, Amaro RE | Biochemistry | 23205906 | Biochemistry | 2012 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/23205906 |
Teach-Discover-Treat (TDT): collaborative computational drug discovery for neglected diseases. | Jansen JM, Cornell W, Tseng YJ, Amaro RE | Journal of molecular graphics & modelling | 23085175 | J Mol Graph Model | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23085175 |
Mechanisms for Benzene Dissociation through the Excited State of T4 Lysozyme L99A Mutant. | Feher VA, Schiffer JM, Mermelstein DJ, Mih N, Pierce LCT, McCammon JA, Amaro RE | Biophysical journal | 30606449 | Biophys J | 2019 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/30606449 |
Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B. | Shi K, Demir Ö, Carpenter MA, Banerjee S, Harki DA, Amaro RE, Harris RS, Aihara H | FASEB bioAdvances | 32123856 | FASEB Bioadv | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32123856 |
Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases. | Prabhu L, Chen L, Wei H, Demir Ö, Safa A, Zeng L, Amaro RE, O'Neil BH, Zhang ZY, Lu T | Molecular bioSystems | 29099132 | Mol Biosyst | 2017 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/29099132 |
Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B. | Shi K, Demir Ö, Carpenter MA, Wagner J, Kurahashi K, Harris RS, Amaro RE, Aihara H | Scientific reports | 29234087 | Sci Rep | 2017 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/29234087 |
Simulation-Based Approaches for Determining Membrane Permeability of Small Compounds. | Lee CT, Comer J, Herndon C, Leung N, Pavlova A, Swift RV, Tung C, Rowley CN, Amaro RE, Chipot C, Wang Y, Gumbart JC | Journal of chemical information and modeling | 27043429 | J Chem Inf Model | 2016 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/27043429 |
A Kepler Workflow Tool for Reproducible AMBER GPU Molecular Dynamics. | Purawat S, Ieong PU, Malmstrom RD, Chan GJ, Yeung AK, Walker RC, Altintas I, Amaro RE | Biophysical journal | 28636905 | Biophys J | 2017 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/28636905 |
Computation-guided discovery of influenza endonuclease inhibitors. | Chen E, Swift RV, Alderson N, Feher VA, Feng GS, Amaro RE | ACS medicinal chemistry letters | 24490002 | ACS Med Chem Lett | 2014 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/24490002 |
Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. | Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P | Nature microbiology | 27595425 | Nat Microbiol | 2016 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/27595425 |
SEEKR: Simulation Enabled Estimation of Kinetic Rates, A Computational Tool to Estimate Molecular Kinetics and Its Application to Trypsin-Benzamidine Binding. | Votapka LW, Jagger BR, Heyneman AL, Amaro RE | The journal of physical chemistry. B | 28191969 | J Phys Chem B | 2017 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/28191969 |
Variable ligand- and receptor-binding hot spots in key strains of influenza neuraminidase. | Votapka L, Demir O, Swift RV, Walker RC, Amaro RE | Journal of molecular and genetic medicine : an international journal of biomedical research | 22872804 | J Mol Genet Med | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22872804 |
Elements of nucleotide specificity in the Trypanosoma brucei mitochondrial RNA editing enzyme RET2. | Demir Ö, Amaro RE | Journal of chemical information and modeling | 22512810 | J Chem Inf Model | 2012 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/22512810 |
Back to the future: can physical models of passive membrane permeability help reduce drug candidate attrition and move us beyond QSPR? | Swift RV, Amaro RE | Chemical biology & drug design | 23066853 | Chem Biol Drug Des | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23066853 |
Computational chemistry and drug discovery: a call to action. | Jansen JM, Amaro RE, Cornell W, Tseng YJ, Walters WP | Future medicinal chemistry | 23088271 | Future Med Chem | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23088271 |
Computational approaches to mapping allosteric pathways. | Feher VA, Durrant JD, Van Wart AT, Amaro RE | Current opinion in structural biology | 24667124 | Curr Opin Struct Biol | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24667124 |
LipidWrapper: an algorithm for generating large-scale membrane models of arbitrary geometry. | Durrant JD, Amaro RE | PLoS computational biology | 25032790 | PLoS Comput Biol | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25032790 |
Weighted Implementation of Suboptimal Paths (WISP): An Optimized Algorithm and Tool for Dynamical Network Analysis. | Van Wart AT, Durrant J, Votapka L, Amaro RE | Journal of chemical theory and computation | 24803851 | J Chem Theory Comput | 2014 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/24803851 |
RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting. | Rajappa-Titu L, Suematsu T, Munoz-Tello P, Long M, Demir Ö, Cheng KJ, Stagno JR, Luecke H, Amaro RE, Aphasizheva I, Aphasizhev R, Thore S | Nucleic acids research | 27744351 | Nucleic Acids Res | 2016 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/27744351 |
Computer-aided discovery of Trypanosoma brucei RNA-editing terminal uridylyl transferase 2 inhibitors. | Demir O, Labaied M, Merritt C, Stuart K, Amaro RE | Chemical biology & drug design | 24903413 | Chem Biol Drug Des | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24903413 |
A Computational Assay that Explores the Hemagglutinin/Neuraminidase Functional Balance Reveals the Neuraminidase Secondary Site as a Novel Anti-Influenza Target. | Amaro RE, Ieong PU, Huber G, Dommer A, Steven AC, Bush RM, Durrant JD, Votapka LW | ACS central science | 30555910 | ACS Cent Sci | 2018 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/30555910 |
Determinants of Oligonucleotide Selectivity of APOBEC3B. | Wagner JR, Demir Ö, Carpenter MA, Aihara H, Harki DA, Harris RS, Amaro RE | Journal of chemical information and modeling | 30130104 | J Chem Inf Model | 2019 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/30130104 |
Progress towards automated Kepler scientific workflows for computer-aided drug discovery and molecular simulations. | Ieong PU, Sørensen J, Vemu PL, Wong CW, Demir Ö, Williams NP, Wang J, Crawl D, Swift RV, Malmstrom RD, Altintas I, Amaro RE | Procedia computer science | 29399238 | Procedia Comput Sci | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/29399238 |
Molecular Simulations Reveal an Unresolved Conformation of the Type IA Protein Kinase A Regulatory Subunit and Suggest Its Role in the cAMP Regulatory Mechanism. | Hirakis SP, Malmstrom RD, Amaro RE | Biochemistry | 28661131 | Biochemistry | 2017 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/28661131 |
A Comparative Study of the Structural Dynamics of Four Terminal Uridylyl Transferases. | Cheng KJ, Demir Ö, Amaro RE | Genes | 28632168 | Genes (Basel) | 2017 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/28632168 |
Dynamics and Molecular Mechanisms of p53 Transcriptional Activation. | Offutt TL, Ieong PU, Demir Ö, Amaro RE | Biochemistry | 30388364 | Biochemistry | 2018 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/30388364 |
Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis. | Torres R, Swift RV, Chim N, Wheatley N, Lan B, Atwood BR, Pujol C, Sankaran B, Bliska JB, Amaro RE, Goulding CW | PloS one | 21966419 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/21966419 |
How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase. | Balasubramaniam D, Schiffer J, Parnell J, Mir SP, Amaro RE, Komives EA | Biochemistry | 25654263 | Biochemistry | 2015 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/25654263 |
Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor. | Goldgof GM, Durrant JD, Ottilie S, Vigil E, Allen KE, Gunawan F, Kostylev M, Henderson KA, Yang J, Schenken J, LaMonte GM, Manary MJ, Murao A, Nachon M, Murray R, Prescott M, McNamara CW, Slayman CW, Amaro RE, Suzuki Y, Winzeler EA | Scientific reports | 27291296 | Sci Rep | 2016 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/27291296 |
Model of the Ankyrin and SOCS Box Protein, ASB9, E3 Ligase Reveals a Mechanism for Dynamic Ubiquitin Transfer. | Schiffer JM, Malmstrom RD, Parnell J, Ramirez-Sarmiento C, Reyes J, Amaro RE, Komives EA | Structure (London, England : 1993) | 27396830 | Structure | 2016 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/27396830 |
Full-length p53 tetramer bound to DNA and its quaternary dynamics. | Demir Ö, Ieong PU, Amaro RE | Oncogene | 27641333 | Oncogene | 2017 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/27641333 |
Knowledge-Based Methods To Train and Optimize Virtual Screening Ensembles. | Swift RV, Jusoh SA, Offutt TL, Li ES, Amaro RE | Journal of chemical information and modeling | 27097522 | J Chem Inf Model | 2016 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/27097522 |
Two Relations to Estimate Membrane Permeability Using Milestoning. | Votapka LW, Lee CT, Amaro RE | The journal of physical chemistry. B | 27154639 | J Phys Chem B | 2016 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/27154639 |
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs. | Wagner JR, Lee CT, Durrant JD, Malmstrom RD, Feher VA, Amaro RE | Chemical reviews | 27074285 | Chem Rev | 2016 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/27074285 |
Multiscale computational modeling of the effects of 2'-deoxy-ATP on cardiac muscle calcium handling. | Hock MT, Teitgen AE, McCabe KJ, Hirakis SP, Huber GA, Regnier M, Amaro RE, McCammon JA, McCulloch AD | Journal of applied physics | 37601331 | J Appl Phys | 2023 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/37601331 |
Equine common variable immunodeficiency: lessons from 100 clinical cases. | Julia M, Felippe B | Equine veterinary education | 39555145 | Equine Vet Educ | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39555145 |
Expression of essential B cell development genes in horses with common variable immunodeficiency. | Tallmadge RL, Such KA, Miller KC, Matychak MB, Felippe MJ | Molecular immunology | 22464097 | Mol Immunol | 2012 Jun | https://www.ncbi.nlm.nih.gov/pubmed/22464097 |
Effects of autologous stromal cells and cytokines on differentiation of equine bone marrow-derived progenitor cells. | Schwab UE, Tallmadge RL, Matychak MB, Felippe MJB | American journal of veterinary research | 28945121 | Am J Vet Res | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28945121 |
Developmental expression of B cell molecules in equine lymphoid tissues. | Prieto JMB, Tallmadge RL, Felippe MJB | Veterinary immunology and immunopathology | 28063478 | Vet Immunol Immunopathol | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28063478 |
Developmental progression of equine immunoglobulin heavy chain variable region diversity. | Tallmadge RL, Tseng CT, King RA, Felippe MJ | Developmental and comparative immunology | 23567345 | Dev Comp Immunol | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23567345 |
Diversity of immunoglobulin lambda light chain gene usage over developmental stages in the horse. | Tallmadge RL, Tseng CT, Felippe MJ | Developmental and comparative immunology | 24726757 | Dev Comp Immunol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24726757 |
Hematopoiesis in the equine fetal liver suggests immune preparedness. | Battista JM, Tallmadge RL, Stokol T, Felippe MJ | Immunogenetics | 25179685 | Immunogenetics | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25179685 |
Bone marrow transcriptome and epigenome profiles of equine common variable immunodeficiency patients unveil block of B lymphocyte differentiation. | Tallmadge RL, Shen L, Tseng CT, Miller SC, Barry J, Felippe MJ | Clinical immunology (Orlando, Fla.) | 25988861 | Clin Immunol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25988861 |
The Horse with Recurrent Fevers and Infections: Approach to Common Variable Immunodeficiency. | Mullen KR, Felippe MJB | The Veterinary clinics of North America. Equine practice | 38789347 | Vet Clin North Am Equine Pract | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38789347 |
Optofluidic tunable microlens by manipulating the liquid meniscus using a flared microfluidic structure. | Mao X, Stratton ZI, Nawaz AA, Lin SC, Huang TJ | Biomicrofluidics | 21267439 | Biomicrofluidics | 2010 Dec 30 | https://www.ncbi.nlm.nih.gov/pubmed/21267439 |
An acoustofluidic micromixer based on oscillating sidewall sharp-edges. | Huang PH, Xie Y, Ahmed D, Rufo J, Nama N, Chen Y, Chan CY, Huang TJ | Lab on a chip | 23896797 | Lab Chip | 2013 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/23896797 |
Surface acoustic wave microfluidics. | Ding X, Li P, Lin SC, Stratton ZS, Nama N, Guo F, Slotcavage D, Mao X, Shi J, Costanzo F, Huang TJ | Lab on a chip | 23900527 | Lab Chip | 2013 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/23900527 |
A reconfigurable plasmofluidic lens. | Zhao C, Liu Y, Zhao Y, Fang N, Huang TJ | Nature communications | 23929463 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23929463 |
Multifunctional porous silicon nanopillar arrays: antireflection, superhydrophobicity, photoluminescence, and surface-enhanced Raman scattering. | Kiraly B, Yang S, Huang TJ | Nanotechnology | 23703091 | Nanotechnology | 2013 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/23703091 |
Tunable nanowire patterning using standing surface acoustic waves. | Chen Y, Ding X, Steven Lin SC, Yang S, Huang PH, Nama N, Zhao Y, Nawaz AA, Guo F, Wang W, Gu Y, Mallouk TE, Huang TJ | ACS nano | 23540330 | ACS Nano | 2013 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/23540330 |
Standing surface acoustic wave based cell coculture. | Li S, Guo F, Chen Y, Ding X, Li P, Wang L, Cameron CE, Huang TJ | Analytical chemistry | 25232648 | Anal Chem | 2014 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/25232648 |
Electrochemically Created Highly Surface Roughened Ag Nanoplate Arrays for SERS Biosensing Applications. | Yang S, Slotcavage D, Mai JD, Guo F, Li S, Zhao Y, Lei Y, Cameron CE, Huang TJ | Journal of materials chemistry. C | 25383191 | J Mater Chem C Mater | 2014 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/25383191 |
Acoustofluidic chemical waveform generator and switch. | Ahmed D, Muddana HS, Lu M, French JB, Ozcelik A, Fang Y, Butler PJ, Benkovic SJ, Manz A, Huang TJ | Analytical chemistry | 25405550 | Anal Chem | 2014 Dec 2 | https://www.ncbi.nlm.nih.gov/pubmed/25405550 |
Selectively manipulable acoustic-powered microswimmers. | Ahmed D, Lu M, Nourhani A, Lammert PE, Stratton Z, Muddana HS, Crespi VH, Huang TJ | Scientific reports | 25993314 | Sci Rep | 2015 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/25993314 |
Molecular plasmonics for biology and nanomedicine. | Zheng YB, Kiraly B, Weiss PS, Huang TJ | Nanomedicine (London, England) | 22630155 | Nanomedicine (Lond) | 2012 May | https://www.ncbi.nlm.nih.gov/pubmed/22630155 |
Probing circulating tumor cells in microfluidics. | Li P, Stratton ZS, Dao M, Ritz J, Huang TJ | Lab on a chip | 23306378 | Lab Chip | 2013 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/23306378 |
Tunable patterning of microparticles and cells using standing surface acoustic waves. | Ding X, Shi J, Lin SC, Yazdi S, Kiraly B, Huang TJ | Lab on a chip | 22648600 | Lab Chip | 2012 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/22648600 |
All-Optical Modulation of Localized Surface Plasmon Coupling in a Hybrid System Composed of Photo-Switchable Gratings and Au Nanodisk Arrays. | Liu YJ, Zheng YB, Liou J, Chiang IK, Khoo IC, Huang TJ | The journal of physical chemistry. C, Nanomaterials and interfaces | 21643480 | J Phys Chem C Nanomater Interfaces | 2011 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/21643480 |
Scalable manufacturing of plasmonic nanodisk dimers and cusp nanostructures using salting-out quenching method and colloidal lithography. | Juluri BK, Chaturvedi N, Hao Q, Lu M, Velegol D, Jensen L, Huang TJ | ACS nano | 21692473 | ACS Nano | 2011 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/21692473 |
Three-dimensional continuous particle focusing in a microfluidic channel via standing surface acoustic waves (SSAW). | Shi J, Yazdi S, Lin SC, Ding X, Chiang IK, Sharp K, Huang TJ | Lab on a chip | 21709881 | Lab Chip | 2011 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/21709881 |
Shape-controlled synthesis of hybrid nanomaterials via three-dimensional hydrodynamic focusing. | Lu M, Yang S, Ho YP, Grigsby CL, Leong KW, Huang TJ | ACS nano | 25268035 | ACS Nano | 2014 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/25268035 |
In situ fabrication of 3D Ag@ZnO nanostructures for microfluidic surface-enhanced Raman scattering systems. | Xie Y, Yang S, Mao Z, Li P, Zhao C, Cohick Z, Huang PH, Huang TJ | ACS nano | 25402207 | ACS Nano | 2014 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/25402207 |
Rare cell isolation and analysis in microfluidics. | Chen Y, Li P, Huang PH, Xie Y, Mai JD, Wang L, Nguyen NT, Huang TJ | Lab on a chip | 24406985 | Lab Chip | 2014 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/24406985 |
Lab-on-a-chip technologies for single-molecule studies. | Zhao Y, Chen D, Yue H, French JB, Rufo J, Benkovic SJ, Huang TJ | Lab on a chip | 23670195 | Lab Chip | 2013 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/23670195 |
Optofluidic imaging: now and beyond. | Zhao Y, Stratton ZS, Guo F, Lapsley MI, Chan CY, Lin SC, Huang TJ | Lab on a chip | 23138193 | Lab Chip | 2013 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/23138193 |
A droplet-based, optofluidic device for high-throughput, quantitative bioanalysis. | Guo F, Lapsley MI, Nawaz AA, Zhao Y, Lin SC, Chen Y, Yang S, Zhao XZ, Huang TJ | Analytical chemistry | 23140515 | Anal Chem | 2012 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/23140515 |
Single-shot characterization of enzymatic reaction constants Km and kcat by an acoustic-driven, bubble-based fast micromixer. | Xie Y, Ahmed D, Lapsley MI, Lin SC, Nawaz AA, Wang L, Huang TJ | Analytical chemistry | 22880882 | Anal Chem | 2012 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/22880882 |
An acoustofluidic micromixer via bubble inception and cavitation from microchannel sidewalls. | Ozcelik A, Ahmed D, Xie Y, Nama N, Qu Z, Nawaz AA, Huang TJ | Analytical chemistry | 24754496 | Anal Chem | 2014 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/24754496 |
Exploiting mechanical biomarkers in microfluidics. | Mao X, Huang TJ | Lab on a chip | 22968689 | Lab Chip | 2012 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/22968689 |
A single-layer, planar, optofluidic switch powered by acoustically driven, oscillating microbubbles. | Huang PH, Ian Lapsley M, Ahmed D, Chen Y, Wang L, Jun Huang T | Applied physics letters | 23112348 | Appl Phys Lett | 2012 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/23112348 |
Standing surface acoustic wave (SSAW) based multichannel cell sorting. | Ding X, Lin SC, Lapsley MI, Li S, Guo X, Chan CY, Chiang IK, Wang L, McCoy JP, Huang TJ | Lab on a chip | 22992833 | Lab Chip | 2012 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/22992833 |
High-speed optical humidity sensors based on chiral sculptured thin films. | Liu YJ, Shi J, Zhang F, Liang H, Xu J, Lakhtakia A, Fonash SJ, Huang TJ | Sensors and actuators. B, Chemical | 30739999 | Sens Actuators B Chem | 2011 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30739999 |
Surface-Enhanced Raman Scattering Study on Graphene-Coated Metallic Nanostructure Substrates. | Hao Q, Wang B, Bossard JA, Kiraly B, Zeng Y, Chiang IK, Jensen L, Werner DH, Huang TJ | The journal of physical chemistry. C, Nanomaterials and interfaces | 24772200 | J Phys Chem C Nanomater Interfaces | 2012 Apr 5 | https://www.ncbi.nlm.nih.gov/pubmed/24772200 |
Microfluidic synthesis of multifunctional Janus particles for biomedical applications. | Yang S, Guo F, Kiraly B, Mao X, Lu M, Leong KW, Huang TJ | Lab on a chip | 22584998 | Lab Chip | 2012 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/22584998 |
Microfluidic opportunities in the field of nutrition. | Li S, Kiehne J, Sinoway LI, Cameron CE, Huang TJ | Lab on a chip | 24056522 | Lab Chip | 2013 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/24056522 |
Label-free measurements of reaction kinetics using a droplet-based optofluidic device. | Mao Z, Guo F, Xie Y, Zhao Y, Lapsley MI, Wang L, Mai JD, Costanzo F, Huang TJ | Journal of laboratory automation | 25249275 | J Lab Autom | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25249275 |
Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves. | Guo F, Zhou W, Li P, Mao Z, Yennawar NH, French JB, Huang TJ | Small (Weinheim an der Bergstrasse, Germany) | 25641793 | Small | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25641793 |
Sub-micrometer-precision, three-dimensional (3D) hydrodynamic focusing via "microfluidic drifting". | Nawaz AA, Zhang X, Mao X, Rufo J, Lin SC, Guo F, Zhao Y, Lapsley M, Li P, McCoy JP, Levine SJ, Huang TJ | Lab on a chip | 24287742 | Lab Chip | 2014 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/24287742 |
Three-dimensional hydrodynamic focusing method for polyplex synthesis. | Lu M, Ho YP, Grigsby CL, Nawaz AA, Leong KW, Huang TJ | ACS nano | 24341632 | ACS Nano | 2014 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/24341632 |
Immunological analyses of whole blood via "microfluidic drifting" based flow cytometric chip. | Nawaz AA, Nissly RH, Li P, Chen Y, Guo F, Li S, Shariff YM, Qureshi AN, Wang L, Huang TJ | Annals of biomedical engineering | 24893596 | Ann Biomed Eng | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24893596 |
Acoustofluidic relay: sequential trapping and transporting of microparticles via acoustically excited oscillating bubbles. | Xie Y, Ahmed D, Lapsley MI, Lu M, Li S, Huang TJ | Journal of laboratory automation | 23592570 | J Lab Autom | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23592570 |
Acoustic separation of circulating tumor cells. | Li P, Mao Z, Peng Z, Zhou L, Chen Y, Huang PH, Truica CI, Drabick JJ, El-Deiry WS, Dao M, Suresh S, Huang TJ | Proceedings of the National Academy of Sciences of the United States of America | 25848039 | Proc Natl Acad Sci U S A | 2015 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/25848039 |
Holographically formed, acoustically switchable gratings based on polymer-dispersed liquid crystals. | Liu YJ, Lu M, Ding X, Leong ES, Lin SC, Shi J, Teng JH, Wang L, Bunning TJ, Huang TJ | Journal of laboratory automation | 22909448 | J Lab Autom | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22909448 |
Tunable, pulsatile chemical gradient generation via acoustically driven oscillating bubbles. | Ahmed D, Chan CY, Lin SC, Muddana HS, Nama N, Benkovic SJ, Huang TJ | Lab on a chip | 23254861 | Lab Chip | 2013 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/23254861 |
Unconventional microfluidics: expanding the discipline. | Nawaz AA, Mao X, Stratton ZS, Huang TJ | Lab on a chip | 23478651 | Lab Chip | 2013 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/23478651 |
Dark-field illumination on zero-mode waveguide/microfluidic hybrid chip reveals T4 replisomal protein interactions. | Zhao Y, Chen D, Yue H, Spiering MM, Zhao C, Benkovic SJ, Huang TJ | Nano letters | 24628474 | Nano Lett | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24628474 |
Large-Scale Fabrication of Three-Dimensional Surface Patterns Using Template-Defined Electrochemical Deposition. | Yang S, Lapsley MI, Cao B, Zhao C, Zhao Y, Hao Q, Kiraly B, Scott J, Li W, Wang L, Lei Y, Huang TJ | Advanced functional materials | 31588203 | Adv Funct Mater | 2013 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/31588203 |
Microfluidic diagnostics for the developing world. | Mao X, Huang TJ | Lab on a chip | 22406768 | Lab Chip | 2012 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/22406768 |
An integrated, multiparametric flow cytometry chip using "microfluidic drifting" based three-dimensional hydrodynamic focusing. | Mao X, Nawaz AA, Lin SC, Lapsley MI, Zhao Y, McCoy JP, El-Deiry WS, Huang TJ | Biomicrofluidics | 22567082 | Biomicrofluidics | 2012 Jun | https://www.ncbi.nlm.nih.gov/pubmed/22567082 |
Continuous enrichment of low-abundance cell samples using standing surface acoustic waves (SSAW). | Chen Y, Li S, Gu Y, Li P, Ding X, Wang L, McCoy JP, Levine SJ, Huang TJ | Lab on a chip | 24413889 | Lab Chip | 2014 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/24413889 |
An on-chip, multichannel droplet sorter using standing surface acoustic waves. | Li S, Ding X, Guo F, Chen Y, Lapsley MI, Lin SC, Wang L, McCoy JP, Cameron CE, Huang TJ | Analytical chemistry | 23647057 | Anal Chem | 2013 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/23647057 |
Optoacoustic tweezers: a programmable, localized cell concentrator based on opto-thermally generated, acoustically activated, surface bubbles. | Xie Y, Zhao C, Zhao Y, Li S, Rufo J, Yang S, Guo F, Huang TJ | Lab on a chip | 23511348 | Lab Chip | 2013 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/23511348 |
Probing cell-cell communication with microfluidic devices. | Guo F, French JB, Li P, Zhao H, Chan CY, Fick JR, Benkovic SJ, Huang TJ | Lab on a chip | 23843092 | Lab Chip | 2013 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/23843092 |
Surface acoustic wave (SAW) acoustophoresis: now and beyond. | Lin SC, Mao X, Huang TJ | Lab on a chip | 22781941 | Lab Chip | 2012 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/22781941 |
Revisiting lab-on-a-chip technology for drug discovery. | Neuži P, Giselbrecht S, Länge K, Huang TJ, Manz A | Nature reviews. Drug discovery | 22850786 | Nat Rev Drug Discov | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22850786 |
Fabrication and characterization of beaded SiC quantum rings with anomalous red spectral shift. | Yang S, Kiraly B, Wang WY, Shang S, Cao B, Zeng H, Zhao Y, Li W, Liu ZK, Cai W, Huang TJ | Advanced materials (Deerfield Beach, Fla.) | 22911493 | Adv Mater | 2012 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/22911493 |
On-chip manipulation of single microparticles, cells, and organisms using surface acoustic waves. | Ding X, Lin SC, Kiraly B, Yue H, Li S, Chiang IK, Shi J, Benkovic SJ, Huang TJ | Proceedings of the National Academy of Sciences of the United States of America | 22733731 | Proc Natl Acad Sci U S A | 2012 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/22733731 |
Superhydrophobic Surface Enhanced Raman Scattering Sensing using Janus Particle Arrays Realized by Site-Specific Electrochemical Growth. | Yang S, Hricko PJ, Huang PH, Li S, Zhao Y, Xie Y, Guo F, Wang L, Huang TJ | Journal of materials chemistry. C | 24748991 | J Mater Chem C Mater | 2014 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/24748991 |
Investigation of acoustic streaming patterns around oscillating sharp edges. | Nama N, Huang PH, Huang TJ, Costanzo F | Lab on a chip | 24903475 | Lab Chip | 2014 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/24903475 |
Cell separation using tilted-angle standing surface acoustic waves. | Ding X, Peng Z, Lin SC, Geri M, Li S, Li P, Chen Y, Dao M, Suresh S, Huang TJ | Proceedings of the National Academy of Sciences of the United States of America | 25157150 | Proc Natl Acad Sci U S A | 2014 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/25157150 |
A reliable and programmable acoustofluidic pump powered by oscillating sharp-edge structures. | Huang PH, Nama N, Mao Z, Li P, Rufo J, Chen Y, Xie Y, Wei CH, Wang L, Huang TJ | Lab on a chip | 25188786 | Lab Chip | 2014 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/25188786 |
Acoustic propulsion of nanorod motors inside living cells. | Wang W, Li S, Mair L, Ahmed S, Huang TJ, Mallouk TE | Angewandte Chemie (International ed. in English) | 24677393 | Angew Chem Int Ed Engl | 2014 Mar 17 | https://www.ncbi.nlm.nih.gov/pubmed/24677393 |
Accelerating drug discovery via organs-on-chips. | Chan CY, Huang PH, Guo F, Ding X, Kapur V, Mai JD, Yuen PK, Huang TJ | Lab on a chip | 24193241 | Lab Chip | 2013 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/24193241 |
Standing surface acoustic wave (SSAW)-based microfluidic cytometer. | Chen Y, Nawaz AA, Zhao Y, Huang PH, McCoy JP, Levine SJ, Wang L, Huang TJ | Lab on a chip | 24406848 | Lab Chip | 2014 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/24406848 |
Theory and experiment on particle trapping and manipulation via optothermally generated bubbles. | Zhao C, Xie Y, Mao Z, Zhao Y, Rufo J, Yang S, Guo F, Mai JD, Huang TJ | Lab on a chip | 24276624 | Lab Chip | 2014 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/24276624 |
Standing surface acoustic wave (SSAW)-based cell washing. | Li S, Ding X, Mao Z, Chen Y, Nama N, Guo F, Li P, Wang L, Cameron CE, Huang TJ | Lab on a chip | 25372273 | Lab Chip | 2015 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/25372273 |
A single-layer, planar, optofluidic Mach-Zehnder interferometer for label-free detection. | Lapsley MI, Chiang IK, Zheng YB, Ding X, Mao X, Huang TJ | Lab on a chip | 21479332 | Lab Chip | 2011 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/21479332 |
Combining the Masking and Scaffolding Modalities of Colloidal Crystal Templates: Plasmonic Nanoparticle Arrays with Multiple Periodicities. | Yang S, Slotcavage D, Mai JD, Liang W, Xie Y, Chen Y, Huang TJ | Chemistry of materials : a publication of the American Chemical Society | 25620849 | Chem Mater | 2014 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/25620849 |
Controlling cell-cell interactions using surface acoustic waves. | Guo F, Li P, French JB, Mao Z, Zhao H, Li S, Nama N, Fick JR, Benkovic SJ, Huang TJ | Proceedings of the National Academy of Sciences of the United States of America | 25535339 | Proc Natl Acad Sci U S A | 2015 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/25535339 |
Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms. | Chavez MG, Yu W, Biehs B, Harada H, Snead ML, Lee JS, Desai TA, Klein OD | Tissue engineering. Part C, Methods | 22742471 | Tissue Eng Part C Methods | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22742471 |
Spry1 and spry2 are essential for development of the temporomandibular joint. | Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD | Journal of dental research | 22328578 | J Dent Res | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22328578 |
Stem cell and biomaterials research in dental tissue engineering and regeneration. | Horst OV, Chavez MG, Jheon AH, Desai T, Klein OD | Dental clinics of North America | 22835534 | Dent Clin North Am | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22835534 |
From molecules to mastication: the development and evolution of teeth. | Jheon AH, Seidel K, Biehs B, Klein OD | Wiley interdisciplinary reviews. Developmental biology | 24009032 | Wiley Interdiscip Rev Dev Biol | 2013 Mar-Apr | https://www.ncbi.nlm.nih.gov/pubmed/24009032 |
Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects. | Jheon AH, Prochazkova M, Meng B, Wen T, Lim YJ, Naveau A, Espinoza R, Cox TC, Sone ED, Ganss B, Siebel CW, Klein OD | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 26179131 | J Bone Miner Res | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/26179131 |
Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. | Castillo D, Seidel K, Salcedo E, Ahn C, de Sauvage FJ, Klein OD, Barlow LA | Development (Cambridge, England) | 24993944 | Development | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24993944 |
On the cutting edge of organ renewal: Identification, regulation, and evolution of incisor stem cells. | Kuang-Hsien Hu J, Mushegyan V, Klein OD | Genesis (New York, N.Y. : 2000) | 24307456 | Genesis | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24307456 |
Identification of novel Fgf enhancers and their role in dental evolution. | Tapaltsyan V, Charles C, Hu J, Mindell D, Ahituv N, Wilson GM, Black BL, Viriot L, Klein OD | Evolution & development | 26086993 | Evol Dev | 2016 Jan-Feb | https://www.ncbi.nlm.nih.gov/pubmed/26086993 |
Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster). | Jheon AH, Prochazkova M, Sherman M, Manoli DS, Shah NM, Carbone L, Klein O | International journal of oral science | 25634121 | Int J Oral Sci | 2015 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/25634121 |
Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. | Charles C, Hovorakova M, Ahn Y, Lyons DB, Marangoni P, Churava S, Biehs B, Jheon A, Lesot H, Balooch G, Krumlauf R, Viriot L, Peterkova R, Klein OD | Development (Cambridge, England) | 21862563 | Development | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21862563 |
FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size. | Petersen CI, Jheon AH, Mostowfi P, Charles C, Ching S, Thirumangalathu S, Barlow LA, Klein OD | PLoS genetics | 21655085 | PLoS Genet | 2011 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21655085 |
Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. | Tian H, Biehs B, Chiu C, Siebel CW, Wu Y, Costa M, de Sauvage FJ, Klein OD | Cell reports | 25818302 | Cell Rep | 2015 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/25818302 |
Replaying evolutionary transitions from the dental fossil record. | Harjunmaa E, Seidel K, Häkkinen T, Renvoisé E, Corfe IJ, Kallonen A, Zhang ZQ, Evans AR, Mikkola ML, Salazar-Ciudad I, Klein OD, Jernvall J | Nature | 25079326 | Nature | 2014 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/25079326 |
Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors. | Juuri E, Saito K, Ahtiainen L, Seidel K, Tummers M, Hochedlinger K, Klein OD, Thesleff I, Michon F | Developmental cell | 22819339 | Dev Cell | 2012 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/22819339 |
Developmental disorders of the dentition: an update. | Klein OD, Oberoi S, Huysseune A, Hovorakova M, Peterka M, Peterkova R | American journal of medical genetics. Part C, Seminars in medical genetics | 24124058 | Am J Med Genet C Semin Med Genet | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24124058 |
Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation. | Goodwin AF, Tidyman WE, Jheon AH, Sharir A, Zheng X, Charles C, Fagin JA, McMahon M, Diekwisch TG, Ganss B, Rauen KA, Klein OD | Human molecular genetics | 24057668 | Hum Mol Genet | 2014 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/24057668 |
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. | Tian H, Biehs B, Warming S, Leong KG, Rangell L, Klein OD, de Sauvage FJ | Nature | 21927002 | Nature | 2011 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/21927002 |
Continuously growing rodent molars result from a predictable quantitative evolutionary change over 50 million years. | Tapaltsyan V, Eronen JT, Lawing AM, Sharir A, Janis C, Jernvall J, Klein OD | Cell reports | 25921530 | Cell Rep | 2015 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/25921530 |
Identification and characterization of small RNAs in Yersinia pestis. | Beauregard A, Smith EA, Petrone BL, Singh N, Karch C, McDonough KA, Wade JT | RNA biology | 23324607 | RNA Biol | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23324607 |
Mapping the Regulatory Network for Salmonella enterica Serovar Typhimurium Invasion. | Smith C, Stringer AM, Mao C, Palumbo MJ, Wade JT | mBio | 27601571 | mBio | 2016 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/27601571 |
FRUIT, a scar-free system for targeted chromosomal mutagenesis, epitope tagging, and promoter replacement in Escherichia coli and Salmonella enterica. | Stringer AM, Singh N, Yermakova A, Petrone BL, Amarasinghe JJ, Reyes-Diaz L, Mantis NJ, Wade JT | PloS one | 23028641 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23028641 |
SuhB Associates with Nus Factors To Facilitate 30S Ribosome Biogenesis in Escherichia coli. | Singh N, Bubunenko M, Smith C, Abbott DM, Stringer AM, Shi R, Court DL, Wade JT | mBio | 26980831 | mBio | 2016 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/26980831 |
Genome-scale analyses of Escherichia coli and Salmonella enterica AraC reveal noncanonical targets and an expanded core regulon. | Stringer AM, Currenti S, Bonocora RP, Baranowski C, Petrone BL, Palumbo MJ, Reilly AA, Zhang Z, Erill I, Wade JT | Journal of bacteriology | 24272778 | J Bacteriol | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24272778 |
Identification of bacterial sRNA regulatory targets using ribosome profiling. | Wang J, Rennie W, Liu C, Carmack CS, Prévost K, Caron MP, Massé E, Ding Y, Wade JT | Nucleic acids research | 26546513 | Nucleic Acids Res | 2015 Dec 2 | https://www.ncbi.nlm.nih.gov/pubmed/26546513 |
Horizontally acquired AT-rich genes in Escherichia coli cause toxicity by sequestering RNA polymerase. | Lamberte LE, Baniulyte G, Singh SS, Stringer AM, Bonocora RP, Stracy M, Kapanidis AN, Wade JT, Grainger DC | Nature microbiology | 28067866 | Nat Microbiol | 2017 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/28067866 |
Genome-Wide Transcriptional Response to Varying RpoS Levels in Escherichia coli K-12. | Wong GT, Bonocora RP, Schep AN, Beeler SM, Lee Fong AJ, Shull LM, Batachari LE, Dillon M, Evans C, Becker CJ, Bush EC, Hardin J, Wade JT, Stoebel DM | Journal of bacteriology | 28115545 | J Bacteriol | 2017 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/28115545 |
Maestro of regulation: Riboswitches orchestrate gene expression at the levels of translation, transcription and mRNA decay. | Bastet L, Turcotte P, Wade JT, Lafontaine DA | RNA biology | 29537923 | RNA Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29537923 |
Non-canonical protein-DNA interactions identified by ChIP are not artifacts. | Bonocora RP, Fitzgerald DM, Stringer AM, Wade JT | BMC genomics | 23586855 | BMC Genomics | 2013 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/23586855 |
Identification of HilD-regulated genes in Salmonella enterica serovar Typhimurium. | Petrone BL, Stringer AM, Wade JT | Journal of bacteriology | 24375101 | J Bacteriol | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24375101 |
Pervasive transcription: illuminating the dark matter of bacterial transcriptomes. | Wade JT, Grainger DC | Nature reviews. Microbiology | 25069631 | Nat Rev Microbiol | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25069631 |
Genome-Scale Mapping of Escherichia coli σ54 Reveals Widespread, Conserved Intragenic Binding. | Bonocora RP, Smith C, Lapierre P, Wade JT | PLoS genetics | 26425847 | PLoS Genet | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26425847 |
Genome-Wide Mapping of the Escherichia coli PhoB Regulon Reveals Many Transcriptionally Inert, Intragenic Binding Sites. | Fitzgerald DM, Stringer AM, Smith C, Lapierre P, Wade JT | mBio | 37067422 | mBio | 2023 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/37067422 |
Comprehensive mapping of the Escherichia coli flagellar regulatory network. | Fitzgerald DM, Bonocora RP, Wade JT | PLoS genetics | 25275371 | PLoS Genet | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25275371 |
ChIP-seq for genome-scale analysis of bacterial DNA-binding proteins. | Bonocora RP, Wade JT | Methods in molecular biology (Clifton, N.J.) | 25665574 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25665574 |
Identification of regulatory RNA in bacterial genomes by genome-scale mapping of transcription start sites. | Singh N, Wade JT | Methods in molecular biology (Clifton, N.J.) | 24318882 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24318882 |
Identification of regulatory targets for the bacterial Nus factor complex. | Baniulyte G, Singh N, Benoit C, Johnson R, Ferguson R, Paramo M, Stringer AM, Scott A, Lapierre P, Wade JT | Nature communications | 29229908 | Nat Commun | 2017 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/29229908 |
Translational control and Rho-dependent transcription termination are intimately linked in riboswitch regulation. | Bastet L, Chauvier A, Singh N, Lussier A, Lamontagne AM, Prévost K, Massé E, Wade JT, Lafontaine DA | Nucleic acids research | 28520932 | Nucleic Acids Res | 2017 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/28520932 |
Coordinated regulation of acid resistance in Escherichia coli. | Aquino P, Honda B, Jaini S, Lyubetskaya A, Hosur K, Chiu JG, Ekladious I, Hu D, Jin L, Sayeg MK, Stettner AI, Wang J, Wong BG, Wong WS, Alexander SL, Ba C, Bensussen SI, Bernstein DB, Braff D, Cha S, Cheng DI, Cho JH, Chou K, Chuang J, Gastler DE, Grasso DJ, Greifenberger JS, Guo C, Hawes AK, Israni DV, Jain SR, Kim J, Lei J, Li H, Li D, Li Q, Mancuso CP, Mao N, Masud SF, Meisel CL, Mi J, Nykyforchyn CS, Park M, Peterson HM, Ramirez AK, Reynolds DS, Rim NG, Saffie JC, Su H, Su WR, Su Y, Sun M, Thommes MM, Tu T, Varongchayakul N, Wagner TE, Weinberg BH, Yang R, Yaroslavsky A, Yoon C, Zhao Y, Zollinger AJ, Stringer AM, Foster JW, Wade J, Raman S, Broude N, Wong WW, Galagan JE | BMC systems biology | 28061857 | BMC Syst Biol | 2017 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/28061857 |
The BvgAS Regulon of Bordetella pertussis. | Moon K, Bonocora RP, Kim DD, Chen Q, Wade JT, Stibitz S, Hinton DM | mBio | 29018122 | mBio | 2017 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/29018122 |
Mapping the Escherichia coli DnaA-binding landscape reveals a preference for binding pairs of closely spaced DNA sites. | Stringer AM, Fitzgerald DM, Wade JT | Microbiology (Reading, England) | 39012340 | Microbiology (Reading) | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/39012340 |
Identification of novel sRNAs in mycobacterial species. | Tsai CH, Baranowski C, Livny J, McDonough KA, Wade JT, Contreras LM | PloS one | 24244498 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24244498 |
Widespread suppression of intragenic transcription initiation by H-NS. | Singh SS, Singh N, Bonocora RP, Fitzgerald DM, Wade JT, Grainger DC | Genes & development | 24449106 | Genes Dev | 2014 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/24449106 |
Regulatory roles of Escherichia coli 5' UTR and ORF-internal RNAs detected by 3' end mapping. | Adams PP, Baniulyte G, Esnault C, Chegireddy K, Singh N, Monge M, Dale RK, Storz G, Wade JT | eLife | 33460557 | Elife | 2021 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/33460557 |
The evolutionary impact of intragenic FliA promoters in proteobacteria. | Fitzgerald DM, Smith C, Lapierre P, Wade JT | Molecular microbiology | 29476659 | Mol Microbiol | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29476659 |
MrpJ Directly Regulates Proteus mirabilis Virulence Factors, Including Fimbriae and Type VI Secretion, during Urinary Tract Infection. | Debnath I, Stringer AM, Smith SN, Bae E, Mobley HLT, Wade JT, Pearson MM | Infection and immunity | 30082479 | Infect Immun | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30082479 |
Chemical Inhibition of Kynureninase Reduces Pseudomonas aeruginosa Quorum Sensing and Virulence Factor Expression. | Kasper SH, Bonocora RP, Wade JT, Musah RA, Cady NC | ACS chemical biology | 26785289 | ACS Chem Biol | 2016 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/26785289 |
Genome-wide mapping of the Escherichia coli PhoB regulon reveals many transcriptionally inert, intragenic binding sites. | Fitzgerald D, Stringer A, Smith C, Lapierre P, Wade JT | bioRxiv : the preprint server for biology | 36798257 | bioRxiv | 2023 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/36798257 |
Probing cell migration in confined environments by plasma lithography. | Junkin M, Wong PK | Biomaterials | 21134692 | Biomaterials | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21134692 |
Electrokinetic stringency control in self-assembled monolayer-based biosensors for multiplex urinary tract infection diagnosis. | Liu T, Sin ML, Pyne JD, Gau V, Liao JC, Wong PK | Nanomedicine : nanotechnology, biology, and medicine | 23891989 | Nanomedicine | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23891989 |
Mechanically induced intercellular calcium communication in confined endothelial structures. | Junkin M, Lu Y, Long J, Deymier PA, Hoying JB, Wong PK | Biomaterials | 23267827 | Biomaterials | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23267827 |
Intelligent Systems and Technology for Integrative and Predictive Medicine: An ACP Approach. | Wang FY, Wong PK | ACM transactions on intelligent systems and technology | 24883228 | ACM Trans Intell Syst Technol | 2013 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/24883228 |
Oncogenic KRAS confers chemoresistance by upregulating NRF2. | Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD | Cancer research | 25339352 | Cancer Res | 2014 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/25339352 |
Cellular self-organization by autocatalytic alignment feedback. | Junkin M, Leung SL, Whitman S, Gregorio CC, Wong PK | Journal of cell science | 22193956 | J Cell Sci | 2011 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/22193956 |
Cellular Architecture Regulates Collective Calcium Signaling and Cell Contractility. | Sun J, Hoying JB, Deymier PA, Zhang DD, Wong PK | PLoS computational biology | 27196735 | PLoS Comput Biol | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27196735 |
Single cell gene expression analysis in injury-induced collective cell migration. | Riahi R, Long M, Yang Y, Dean Z, Zhang DD, Slepian MJ, Wong PK | Integrative biology : quantitative biosciences from nano to macro | 24336811 | Integr Biol (Camb) | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24336811 |
A UAV-Mounted Whole Cell Biosensor System for Environmental Monitoring Applications. | Lu Y, Macias D, Dean ZS, Kreger NR, Wong PK | IEEE transactions on nanobioscience | 26584498 | IEEE Trans Nanobioscience | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26584498 |
Advances in wound-healing assays for probing collective cell migration. | Riahi R, Yang Y, Zhang DD, Wong PK | Journal of laboratory automation | 22357609 | J Lab Autom | 2012 Feb | https://www.ncbi.nlm.nih.gov/pubmed/22357609 |
A nanobiosensor for dynamic single cell analysis during microvascular self-organization. | Wang S, Sun J, Zhang DD, Wong PK | Nanoscale | 27547924 | Nanoscale | 2016 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/27547924 |
Calcium wave propagation in networks of endothelial cells: model-based theoretical and experimental study. | Long J, Junkin M, Wong PK, Hoying J, Deymier P | PLoS computational biology | 23300426 | PLoS Comput Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23300426 |
Single cell antimicrobial susceptibility testing by confined microchannels and electrokinetic loading. | Lu Y, Gao J, Zhang DD, Gau V, Liao JC, Wong PK | Analytical chemistry | 23445209 | Anal Chem | 2013 Apr 16 | https://www.ncbi.nlm.nih.gov/pubmed/23445209 |
An AC electrokinetics facilitated biosensor cassette for rapid pathogen identification. | Ouyang M, Mohan R, Lu Y, Liu T, Mach KE, Sin ML, McComb M, Joshi J, Gau V, Wong PK, Liao JC | The Analyst | 23626988 | Analyst | 2013 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/23626988 |
Electrokinetic focusing and separation of mammalian cells in conductive biological fluids. | Gao J, Riahi R, Sin ML, Zhang S, Wong PK | The Analyst | 22937529 | Analyst | 2012 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/22937529 |
Mapping photothermally induced gene expression in living cells and tissues by nanorod-locked nucleic acid complexes. | Riahi R, Wang S, Long M, Li N, Chiou PY, Zhang DD, Wong PK | ACS nano | 24645754 | ACS Nano | 2014 Apr 22 | https://www.ncbi.nlm.nih.gov/pubmed/24645754 |
Advances in techniques for probing mechanoregulation of tissue morphogenesis. | Sun J, Xiao Y, Wang S, Slepian MJ, Wong PK | Journal of laboratory automation | 25331491 | J Lab Autom | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25331491 |
Spatiotemporal dynamics of microRNA during epithelial collective cell migration. | Dean ZS, Riahi R, Wong PK | Biomaterials | 25453946 | Biomaterials | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25453946 |
AC Electrokinetics of Physiological Fluids for Biomedical Applications. | Lu Y, Liu T, Lamanda AC, Sin ML, Gau V, Liao JC, Wong PK | Journal of laboratory automation | 25487557 | J Lab Autom | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25487557 |
Intercellular Tension Negatively Regulates Angiogenic Sprouting of Endothelial Tip Cells via Notch1-Dll4 Signaling. | Wang S, Sun J, Xiao Y, Lu Y, Zhang DD, Wong PK | Advanced biosystems | 30662935 | Adv Biosyst | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30662935 |
Notch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration. | Riahi R, Sun J, Wang S, Long M, Zhang DD, Wong PK | Nature communications | 25766473 | Nat Commun | 2015 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/25766473 |
Long-range electrothermal fluid motion in microfluidic systems. | Lu Y, Ren Q, Liu T, Leung SL, Gau V, Liao JC, Chan CL, Wong PK | International journal of heat and mass transfer | 27127306 | Int J Heat Mass Transf | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27127306 |
Probing Leader Cells in Endothelial Collective Migration by Plasma Lithography Geometric Confinement. | Yang Y, Jamilpour N, Yao B, Dean ZS, Riahi R, Wong PK | Scientific reports | 26936382 | Sci Rep | 2016 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/26936382 |
Probing mechanoregulation of neuronal differentiation by plasma lithography patterned elastomeric substrates. | Nam KH, Jamilpour N, Mfoumou E, Wang FY, Zhang DD, Wong PK | Scientific reports | 25376886 | Sci Rep | 2014 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/25376886 |
A microfluidic model for organ-specific extravasation of circulating tumor cells. | Riahi R, Yang YL, Kim H, Jiang L, Wong PK, Zohar Y | Biomicrofluidics | 24803959 | Biomicrofluidics | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24803959 |
Biosensor diagnosis of urinary tract infections: a path to better treatment? | Mach KE, Wong PK, Liao JC | Trends in pharmacological sciences | 21458868 | Trends Pharmacol Sci | 2011 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21458868 |
Hybrid electrokinetic manipulation in high-conductivity media. | Gao J, Sin ML, Liu T, Gau V, Liao JC, Wong PK | Lab on a chip | 21487576 | Lab Chip | 2011 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/21487576 |
Plasma lithography surface patterning for creation of cell networks. | Junkin M, Leung SL, Yang Y, Lu Y, Volmering J, Wong PK | Journal of visualized experiments : JoVE | 21694697 | J Vis Exp | 2011 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/21694697 |
Single cell nanobiosensors for dynamic gene expression profiling in native tissue microenvironments. | Wang S, Riahi R, Li N, Zhang DD, Wong PK | Advanced materials (Deerfield Beach, Fla.) | 26314800 | Adv Mater | 2015 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/26314800 |
Molecular detection of bacterial pathogens using microparticle enhanced double-stranded DNA probes. | Riahi R, Mach KE, Mohan R, Liao JC, Wong PK | Analytical chemistry | 21718053 | Anal Chem | 2011 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/21718053 |
In situ electrokinetic enhancement for self-assembled-monolayer-based electrochemical biosensing. | Sin ML, Liu T, Pyne JD, Gau V, Liao JC, Wong PK | Analytical chemistry | 22397486 | Anal Chem | 2012 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/22397486 |
Geometric control of capillary architecture via cell-matrix mechanical interactions. | Sun J, Jamilpour N, Wang FY, Wong PK | Biomaterials | 24439400 | Biomaterials | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24439400 |
Detection of mRNA in living cells by double-stranded locked nucleic acid probes. | Riahi R, Dean Z, Wu TH, Teitell MA, Chiou PY, Zhang DD, Wong PK | The Analyst | 23772441 | Analyst | 2013 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/23772441 |
A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single cells. | Wang S, Xiao Y, Zhang DD, Wong PK | Biomaterials | 29190498 | Biomaterials | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29190498 |
Collective Cell Migration in 3D Epithelial Wound Healing. | Xiao Y, Riahi R, Torab P, Zhang DD, Wong PK | ACS nano | 30758172 | ACS Nano | 2019 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/30758172 |
Statistical metamodeling for revealing synergistic antimicrobial interactions. | Chen HC, Gau V, Zhang DD, Liao JC, Wang FY, Wong PK | PloS one | 21124958 | PLoS One | 2010 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/21124958 |
Rapid antimicrobial susceptibility testing with electrokinetics enhanced biosensors for diagnosis of acute bacterial infections. | Liu T, Lu Y, Gau V, Liao JC, Wong PK | Annals of biomedical engineering | 24889716 | Ann Biomed Eng | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24889716 |
A Universal Electrode Approach for Automated Electrochemical Molecular Analyses. | Sin ML, Gau V, Liao JC, Wong PK | Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems | 24860248 | J Microelectromech Syst | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24860248 |
A Microfiltration Device for Urogenital Schistosomiasis Diagnostics. | Xiao Y, Lu Y, Hsieh M, Liao J, Wong PK | PloS one | 27124499 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27124499 |
Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality. | Pappas CT, Mayfield RM, Henderson C, Jamilpour N, Cover C, Hernandez Z, Hutchinson KR, Chu M, Nam KH, Valdez JM, Wong PK, Granzier HL, Gregorio CC | Proceedings of the National Academy of Sciences of the United States of America | 26487682 | Proc Natl Acad Sci U S A | 2015 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/26487682 |
Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1. | Chu M, Novak SM, Cover C, Wang AA, Chinyere IR, Juneman EB, Zarnescu DC, Wong PK, Gregorio CC | Circulation | 29101288 | Circulation | 2018 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/29101288 |
Intestinal stem cell growth and differentiation on a tubular scaffold with evaluation in small and large animals. | Shaffiey SA, Jia H, Keane T, Costello C, Wasserman D, Quidgley M, Dziki J, Badylak S, Sodhi CP, March JC, Hackam DJ | Regenerative medicine | 26395928 | Regen Med | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/26395928 |
Engineering commensal bacteria for prophylaxis against infection. | Goh YL, He H, March JC | Current opinion in biotechnology | 22459613 | Curr Opin Biotechnol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22459613 |
Engineered commensal bacteria reprogram intestinal cells into glucose-responsive insulin-secreting cells for the treatment of diabetes. | Duan FF, Liu JH, March JC | Diabetes | 25626737 | Diabetes | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25626737 |
3-D intestinal scaffolds for evaluating the therapeutic potential of probiotics. | Costello CM, Sorna RM, Goh YL, Cengic I, Jain NK, March JC | Molecular pharmaceutics | 24798584 | Mol Pharm | 2014 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/24798584 |
Secretion of insulinotropic proteins by commensal bacteria: rewiring the gut to treat diabetes. | Duan F, Curtis KL, March JC | Applied and environmental microbiology | 18836005 | Appl Environ Microbiol | 2008 Dec | https://www.ncbi.nlm.nih.gov/pubmed/18836005 |
Generation of an artificial intestine for the management of short bowel syndrome. | Ladd MR, Niño DF, March JC, Sodhi CP, Hackam DJ | Current opinion in organ transplantation | 26867049 | Curr Opin Organ Transplant | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26867049 |
Salmonella enterica Serovar Typhimurium Increases Functional PD-L1 Synergistically with Gamma Interferon in Intestinal Epithelial Cells via Salmonella Pathogenicity Island 2. | Sahler JM, Eade CR, Altier C, March JC | Infection and immunity | 29440366 | Infect Immun | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29440366 |
Synthetic small intestinal scaffolds for improved studies of intestinal differentiation. | Costello CM, Hongpeng J, Shaffiey S, Yu J, Jain NK, Hackam D, March JC | Biotechnology and bioengineering | 24390638 | Biotechnol Bioeng | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24390638 |
A universal DNA-based protein detection system. | Tran TN, Cui J, Hartman MR, Peng S, Funabashi H, Duan F, Yang D, March JC, Lis JT, Cui H, Luo D | Journal of the American Chemical Society | 23978265 | J Am Chem Soc | 2013 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/23978265 |
SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development. | Wei D, Goldfarb D, Song S, Cannon C, Yan F, Sakellariou-Thompson D, Emanuele M, Major MB, Weissman BE, Kuwahara Y | Molecular cancer research : MCR | 25009291 | Mol Cancer Res | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25009291 |
Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination. | Hast BE, Cloer EW, Goldfarb D, Li H, Siesser PF, Yan F, Walter V, Zheng N, Hayes DN, Major MB | Cancer research | 24322982 | Cancer Res | 2014 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/24322982 |
The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase. | Onyenwoke RU, Sexton JZ, Yan F, Díaz MC, Forsberg LJ, Major MB, Brenman JE | The Biochemical journal | 26195823 | Biochem J | 2015 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/26195823 |
Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination. | Hast BE, Goldfarb D, Mulvaney KM, Hast MA, Siesser PF, Yan F, Hayes DN, Major MB | Cancer research | 23382044 | Cancer Res | 2013 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/23382044 |
Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase. | Kim TY, Siesser PF, Rossman KL, Goldfarb D, Mackinnon K, Yan F, Yi X, MacCoss MJ, Moon RT, Der CJ, Major MB | Molecular and cellular biology | 25332235 | Mol Cell Biol | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25332235 |
FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma. | Walker MP, Stopford CM, Cederlund M, Fang F, Jahn C, Rabinowitz AD, Goldfarb D, Graham DM, Yan F, Deal AM, Fedoriw Y, Richards KL, Davis IJ, Weidinger G, Damania B, Major MB | Science signaling | 25650440 | Sci Signal | 2015 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/25650440 |
BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization. | Orvis T, Hepperla A, Walter V, Song S, Simon J, Parker J, Wilkerson MD, Desai N, Major MB, Hayes DN, Davis IJ, Weissman B | Cancer research | 25115300 | Cancer Res | 2014 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/25115300 |
USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds. | Madan B, Walker MP, Young R, Quick L, Orgel KA, Ryan M, Gupta P, Henrich IC, Ferrer M, Marine S, Roberts BS, Arthur WT, Berndt JD, Oliveira AM, Moon RT, Virshup DM, Chou MM, Major MB | Proceedings of the National Academy of Sciences of the United States of America | 27162353 | Proc Natl Acad Sci U S A | 2016 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/27162353 |
FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. | Siesser PF, Motolese M, Walker MP, Goldfarb D, Gewain K, Yan F, Kulikauskas RM, Chien AJ, Wordeman L, Major MB | Science signaling | 22949735 | Sci Signal | 2012 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/22949735 |
Dynamics and evolution of β-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening. | Shah PK, Walker MP, Sims CE, Major MB, Allbritton NL | Integrative biology : quantitative biosciences from nano to macro | 24871928 | Integr Biol (Camb) | 2014 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/24871928 |
Modulation of Kaposi's sarcoma-associated herpesvirus interleukin-6 function by hypoxia-upregulated protein 1. | Giffin L, Yan F, Ben Major M, Damania B | Journal of virology | 24920810 | J Virol | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24920810 |
Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens. | Amberg-Johnson K, Hari SB, Ganesan SM, Lorenzi HA, Sauer RT, Niles JC, Yeh E | eLife | 28826494 | Elife | 2017 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/28826494 |
Direct and specific chemical control of eukaryotic translation with a synthetic RNA-protein interaction. | Goldfless SJ, Belmont BJ, de Paz AM, Liu JF, Niles JC | Nucleic acids research | 22275521 | Nucleic Acids Res | 2012 May | https://www.ncbi.nlm.nih.gov/pubmed/22275521 |
Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite. | Dankwa S, Lim C, Bei AK, Jiang RH, Abshire JR, Patel SD, Goldberg JM, Moreno Y, Kono M, Niles JC, Duraisingh MT | Nature communications | 27041489 | Nat Commun | 2016 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/27041489 |
An integrated platform for genome engineering and gene expression perturbation in Plasmodium falciparum. | Nasamu AS, Falla A, Pasaje CFA, Wall BA, Wagner JC, Ganesan SM, Goldfless SJ, Niles JC | Scientific reports | 33431920 | Sci Rep | 2021 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/33431920 |
Versatile control of Plasmodium falciparum gene expression with an inducible protein-RNA interaction. | Goldfless SJ, Wagner JC, Niles JC | Nature communications | 25370483 | Nat Commun | 2014 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/25370483 |
Inducible control of subcellular RNA localization using a synthetic protein-RNA aptamer interaction. | Belmont BJ, Niles JC | PloS one | 23056498 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23056498 |
Synthetic RNA-protein modules integrated with native translation mechanisms to control gene expression in malaria parasites. | Ganesan SM, Falla A, Goldfless SJ, Nasamu AS, Niles JC | Nature communications | 26925876 | Nat Commun | 2016 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26925876 |
Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum. | Wagner JC, Platt RJ, Goldfless SJ, Zhang F, Niles JC | Nature methods | 25108687 | Nat Methods | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25108687 |
Quantification of labile heme in live malaria parasites using a genetically encoded biosensor. | Abshire JR, Rowlands CJ, Ganesan SM, So PT, Niles JC | Proceedings of the National Academy of Sciences of the United States of America | 28242687 | Proc Natl Acad Sci U S A | 2017 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/28242687 |
An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum. | Wagner JC, Goldfless SJ, Ganesan SM, Lee MC, Fidock DA, Niles JC | Malaria journal | 24160265 | Malar J | 2013 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/24160265 |
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. | Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS, Thiru P, Saeij JPJ, Carruthers VB, Niles JC, Lourido S | Cell | 27594426 | Cell | 2016 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/27594426 |
Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis. | Istvan ES, Das S, Bhatnagar S, Beck JR, Owen E, Llinas M, Ganesan SM, Niles JC, Winzeler E, Vaidya AB, Goldberg DE | eLife | 30888318 | Elife | 2019 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/30888318 |
Identification of malaria parasite-infected red blood cell surface aptamers by inertial microfluidic SELEX (I-SELEX). | Birch CM, Hou HW, Han J, Niles JC | Scientific reports | 26126714 | Sci Rep | 2015 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/26126714 |
ATG8 Is Essential Specifically for an Autophagy-Independent Function in Apicoplast Biogenesis in Blood-Stage Malaria Parasites. | Walczak M, Ganesan SM, Niles JC, Yeh E | mBio | 29295911 | mBio | 2018 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/29295911 |
The star-nosed mole reveals clues to the molecular basis of mammalian touch. | Gerhold KA, Pellegrino M, Tsunozaki M, Morita T, Leitch DB, Tsuruda PR, Brem RB, Catania KC, Bautista DM | PloS one | 23383028 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23383028 |
TRPA1: A gatekeeper for inflammation. | Bautista DM, Pellegrino M, Tsunozaki M | Annual review of physiology | 23020579 | Annu Rev Physiol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23020579 |
The ion channel TRPA1 is required for chronic itch. | Wilson SR, Nelson AM, Batia L, Morita T, Estandian D, Owens DM, Lumpkin EA, Bautista DM | The Journal of neuroscience : the official journal of the Society for Neuroscience | 23719797 | J Neurosci | 2013 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/23719797 |
The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch. | Wilson SR, Thé L, Batia LM, Beattie K, Katibah GE, McClain SP, Pellegrino M, Estandian DM, Bautista DM | Cell | 24094650 | Cell | 2013 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/24094650 |
Mammalian touch catches up. | Walsh CM, Bautista DM, Lumpkin EA | Current opinion in neurobiology | 26100741 | Curr Opin Neurobiol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26100741 |
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch. | Wilson SR, Gerhold KA, Bifolck-Fisher A, Liu Q, Patel KN, Dong X, Bautista DM | Nature neuroscience | 21460831 | Nat Neurosci | 2011 May | https://www.ncbi.nlm.nih.gov/pubmed/21460831 |
Engineering cortical neuron polarity with nanomagnets on a chip. | Kunze A, Tseng P, Godzich C, Murray C, Caputo A, Schweizer FE, Di Carlo D | ACS nano | 25801533 | ACS Nano | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25801533 |
Flexible and stretchable micromagnet arrays for tunable biointerfacing. | Tseng P, Lin J, Owsley K, Kong J, Kunze A, Murray C, Di Carlo D | Advanced materials (Deerfield Beach, Fla.) | 25537971 | Adv Mater | 2015 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/25537971 |
Magnetic nanoparticle-mediated massively parallel mechanical modulation of single-cell behavior. | Tseng P, Judy JW, Di Carlo D | Nature methods | 23064517 | Nat Methods | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23064517 |
Probing Cell Adhesion Profiles with a Microscale Adhesive Choice Assay. | Kittur H, Tay A, Hua A, Yu M, Di Carlo D | Biophysical journal | 29045879 | Biophys J | 2017 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/29045879 |
Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner. | Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA Jr | British journal of pharmacology | 27352269 | Br J Pharmacol | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27352269 |
Metallization and biopatterning on ultra-flexible substrates via dextran sacrificial layers. | Tseng P, Pushkarsky I, Di Carlo D | PloS one | 25153326 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25153326 |
Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks. | Griffin DR, Weaver WM, Scumpia PO, Di Carlo D, Segura T | Nature materials | 26030305 | Nat Mater | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26030305 |
The Age of Cortical Neural Networks Affects Their Interactions with Magnetic Nanoparticles. | Tay A, Kunze A, Jun D, Hoek E, Di Carlo D | Small (Weinheim an der Bergstrasse, Germany) | 27228954 | Small | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27228954 |
High-Throughput Microfluidic Sorting of Live Magnetotactic Bacteria. | Tay A, Pfeiffer D, Rowe K, Tannenbaum A, Popp F, Strangeway R, Schüler D, Di Carlo D | Applied and environmental microbiology | 29959254 | Appl Environ Microbiol | 2018 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/29959254 |
Advances in high-throughput single-cell microtechnologies. | Weaver WM, Tseng P, Kunze A, Masaeli M, Chung AJ, Dudani JS, Kittur H, Kulkarni RP, Di Carlo D | Current opinion in biotechnology | 24484889 | Curr Opin Biotechnol | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24484889 |
Substrates with patterned extracellular matrix and subcellular stiffness gradients reveal local biomechanical responses. | Tseng P, Di Carlo D | Advanced materials (Deerfield Beach, Fla.) | 24323894 | Adv Mater | 2014 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/24323894 |
Modulating motility of intracellular vesicles in cortical neurons with nanomagnetic forces on-chip. | Kunze A, Murray CT, Godzich C, Lin J, Owsley K, Tay A, Di Carlo D | Lab on a chip | 28164203 | Lab Chip | 2017 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/28164203 |
Elastomeric sensor surfaces for high-throughput single-cell force cytometry. | Pushkarsky I, Tseng P, Black D, France B, Warfe L, Koziol-White CJ, Jester WF Jr, Trinh RK, Lin J, Scumpia PO, Morrison SL, Panettieri RA Jr, Damoiseaux R, Di Carlo D | Nature biomedical engineering | 31015629 | Nat Biomed Eng | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31015629 |
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Induction of Calcium Influx in Cortical Neural Networks by Nanomagnetic Forces. | Tay A, Kunze A, Murray C, Di Carlo D | ACS nano | 26805612 | ACS Nano | 2016 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/26805612 |
Quantitative Magnetic Separation of Particles and Cells Using Gradient Magnetic Ratcheting. | Murray C, Pao E, Tseng P, Aftab S, Kulkarni R, Rettig M, Di Carlo D | Small (Weinheim an der Bergstrasse, Germany) | 26890496 | Small | 2016 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/26890496 |
Optical highlighter molecules in neurobiology. | Datta SR, Patterson GH | Current opinion in neurobiology | 22129781 | Curr Opin Neurobiol | 2012 Feb | https://www.ncbi.nlm.nih.gov/pubmed/22129781 |
Mapping Sub-Second Structure in Mouse Behavior. | Wiltschko AB, Johnson MJ, Iurilli G, Peterson RE, Katon JM, Pashkovski SL, Abraira VE, Adams RP, Datta SR | Neuron | 26687221 | Neuron | 2015 Dec 16 | https://www.ncbi.nlm.nih.gov/pubmed/26687221 |
Detection and avoidance of a carnivore odor by prey. | Ferrero DM, Lemon JK, Fluegge D, Pashkovski SL, Korzan WJ, Datta SR, Spehr M, Fendt M, Liberles SD | Proceedings of the National Academy of Sciences of the United States of America | 21690383 | Proc Natl Acad Sci U S A | 2011 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/21690383 |
Shh-proteoglycan interactions regulate maturation of olfactory glomerular circuitry. | Persson L, Witt RM, Galligan M, Greer PL, Eisner A, Pazyra-Murphy MF, Datta SR, Segal RA | Developmental neurobiology | 24913191 | Dev Neurobiol | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24913191 |
Olfactory maps, circuits and computations. | Giessel AJ, Datta SR | Current opinion in neurobiology | 24492088 | Curr Opin Neurobiol | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24492088 |
Distinct representations of olfactory information in different cortical centres. | Sosulski DL, Bloom ML, Cutforth T, Axel R, Datta SR | Nature | 21451525 | Nature | 2011 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/21451525 |
A Family of non-GPCR Chemosensors Defines an Alternative Logic for Mammalian Olfaction. | Greer PL, Bear DM, Lassance JM, Bloom ML, Tsukahara T, Pashkovski SL, Masuda FK, Nowlan AC, Kirchner R, Hoekstra HE, Datta SR | Cell | 27238024 | Cell | 2016 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/27238024 |
Non-invasive transdermal two-dimensional mapping of cutaneous oxygenation with a rapid-drying liquid bandage. | Li Z, Roussakis E, Koolen PG, Ibrahim AM, Kim K, Rose LF, Wu J, Nichols AJ, Baek Y, Birngruber R, Apiou-Sbirlea G, Matyal R, Huang T, Chan R, Lin SJ, Evans CL | Biomedical optics express | 25426308 | Biomed Opt Express | 2014 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/25426308 |
Click-assembled, oxygen-sensing nanoconjugates for depth-resolved, near-infrared imaging in a 3D cancer model. | Nichols AJ, Roussakis E, Klein OJ, Evans CL | Angewandte Chemie (International ed. in English) | 24590700 | Angew Chem Int Ed Engl | 2014 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24590700 |
In vitro optimization of EtNBS-PDT against hypoxic tumor environments with a tiered, high-content, 3D model optical screening platform. | Klein OJ, Bhayana B, Park YJ, Evans CL | Molecular pharmaceutics | 22946843 | Mol Pharm | 2012 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/22946843 |
Longitudinal, label-free, quantitative tracking of cell death and viability in a 3D tumor model with OCT. | Jung Y, Klein OJ, Wang H, Evans CL | Scientific reports | 27248849 | Sci Rep | 2016 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/27248849 |
An Integrin-Targeted, Highly Diffusive Construct for Photodynamic Therapy. | Klein OJ, Yuan H, Nowell NH, Kaittanis C, Josephson L, Evans CL | Scientific reports | 29042620 | Sci Rep | 2017 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/29042620 |
Structure-function relationships of Nile blue (EtNBS) derivatives as antimicrobial photosensitizers. | Vecchio D, Bhayana B, Huang L, Carrasco E, Evans CL, Hamblin MR | European journal of medicinal chemistry | 24561676 | Eur J Med Chem | 2014 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/24561676 |
PLGA nanoparticle encapsulation reduces toxicity while retaining the therapeutic efficacy of EtNBS-PDT in vitro. | Hung HI, Klein OJ, Peterson SW, Rokosh SR, Osseiran S, Nowell NH, Evans CL | Scientific reports | 27686626 | Sci Rep | 2016 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/27686626 |
Label-Free, Longitudinal Visualization of PDT Response In Vitro with Optical Coherence Tomography. | Jung Y, Nichols AJ, Klein OJ, Roussakis E, Evans CL | Israel journal of chemistry | 23316088 | Isr J Chem | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23316088 |
3D-resolved targeting of photodynamic therapy using temporal focusing. | Rowlands CJ, Wu J, Uzel SG, Klein O, Evans CL, So PT | Laser physics letters | 25620902 | Laser Phys Lett | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25620902 |
Comprehensive evaluation of peripheral nerve regeneration in the acute healing phase using tissue clearing and optical microscopy in a rodent model. | Jung Y, Ng JH, Keating CP, Senthil-Kumar P, Zhao J, Randolph MA, Winograd JM, Evans CL | PloS one | 24714405 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24714405 |
Video-rate scanning confocal microscopy and microendoscopy. | Nichols AJ, Evans CL | Journal of visualized experiments : JoVE | 22042305 | J Vis Exp | 2011 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/22042305 |
Bright, "Clickable" Porphyrins for the Visualization of Oxygenation under Ambient Light. | Roussakis E, Li Z, Nowell NH, Nichols AJ, Evans CL | Angewandte Chemie (International ed. in English) | 26510549 | Angew Chem Int Ed Engl | 2015 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/26510549 |
Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy. | Kessel D, Evans CL | Photochemistry and photobiology | 27096545 | Photochem Photobiol | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27096545 |
Longitudinal, quantitative monitoring of therapeutic response in 3D in vitro tumor models with OCT for high-content therapeutic screening. | Klein OJ, Jung YK, Evans CL | Methods (San Diego, Calif.) | 24013042 | Methods | 2014 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/24013042 |
Longitudinal, 3D in vivo imaging of sebaceous glands by coherent anti-stokes Raman scattering microscopy: normal function and response to cryotherapy. | Jung Y, Tam J, Ray Jalian H, Rox Anderson R, Evans CL | The Journal of investigative dermatology | 25026458 | J Invest Dermatol | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25026458 |
Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT. | Evans CL, Abu-Yousif AO, Park YJ, Klein OJ, Celli JP, Rizvi I, Zheng X, Hasan T | PloS one | 21876751 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/21876751 |
Molecular tension sensors report forces generated by single integrin molecules in living cells. | Morimatsu M, Mekhdjian AH, Adhikari AS, Dunn AR | Nano letters | 23859772 | Nano Lett | 2013 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/23859772 |
Single Molecule Force Measurements in Living Cells Reveal a Minimally Tensioned Integrin State. | Chang AC, Mekhdjian AH, Morimatsu M, Denisin AK, Pruitt BL, Dunn AR | ACS nano | 27779848 | ACS Nano | 2016 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/27779848 |
Mechanical systems biology of C. elegans touch sensation. | Krieg M, Dunn AR, Goodman MB | BioEssays : news and reviews in molecular, cellular and developmental biology | 25597279 | Bioessays | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25597279 |
Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force. | Buckley CD, Tan J, Anderson KL, Hanein D, Volkmann N, Weis WI, Nelson WJ, Dunn AR | Science (New York, N.Y.) | 25359979 | Science | 2014 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/25359979 |
Mechanical control of the sense of touch by β-spectrin. | Krieg M, Dunn AR, Goodman MB | Nature cell biology | 24561618 | Nat Cell Biol | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24561618 |
E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch. | Borghi N, Sorokina M, Shcherbakova OG, Weis WI, Pruitt BL, Nelson WJ, Dunn AR | Proceedings of the National Academy of Sciences of the United States of America | 22802638 | Proc Natl Acad Sci U S A | 2012 Jul 31 | https://www.ncbi.nlm.nih.gov/pubmed/22802638 |
How Hydra Eats. | Dunn AR | Biophysical journal | 27074672 | Biophys J | 2016 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/27074672 |
Strain tunes proteolytic degradation and diffusive transport in fibrin networks. | Adhikari AS, Mekhdjian AH, Dunn AR | Biomacromolecules | 22185486 | Biomacromolecules | 2012 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/22185486 |
Multiplexed Fluid Flow Device to Study Cellular Response to Tunable Shear Stress Gradients. | Ostrowski MA, Huang EY, Surya VN, Poplawski C, Barakat JM, Lin GL, Fuller GG, Dunn AR | Annals of biomedical engineering | 26589597 | Ann Biomed Eng | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26589597 |
Multiplexed single-molecule force proteolysis measurements using magnetic tweezers. | Adhikari AS, Chai J, Dunn AR | Journal of visualized experiments : JoVE | 22871786 | J Vis Exp | 2012 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/22871786 |
Quantification of nanowire penetration into living cells. | Xu AM, Aalipour A, Leal-Ortiz S, Mekhdjian AH, Xie X, Dunn AR, Garner CC, Melosh NA | Nature communications | 24710350 | Nat Commun | 2014 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/24710350 |
Microvascular endothelial cells migrate upstream and align against the shear stress field created by impinging flow. | Ostrowski MA, Huang NF, Walker TW, Verwijlen T, Poplawski C, Khoo AS, Cooke JP, Fuller GG, Dunn AR | Biophysical journal | 24461011 | Biophys J | 2014 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/24461011 |
Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress. | Surya VN, Michalaki E, Huang EY, Fuller GG, Dunn AR | Journal of the Royal Society, Interface | 27974574 | J R Soc Interface | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27974574 |
Conformational dynamics accompanying the proteolytic degradation of trimeric collagen I by collagenases. | Adhikari AS, Glassey E, Dunn AR | Journal of the American Chemical Society | 22720833 | J Am Chem Soc | 2012 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/22720833 |
The CDC42-interacting protein 4 controls epithelial cell cohesion and tumor dissemination. | Rolland Y, Marighetti P, Malinverno C, Confalonieri S, Luise C, Ducano N, Palamidessi A, Bisi S, Kajiho H, Troglio F, Shcherbakova OG, Dunn AR, Oldani A, Lanzetti L, Di Fiore PP, Disanza A, Scita G | Developmental cell | 25203208 | Dev Cell | 2014 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/25203208 |
Mechanical load induces a 100-fold increase in the rate of collagen proteolysis by MMP-1. | Adhikari AS, Chai J, Dunn AR | Journal of the American Chemical Society | 21247159 | J Am Chem Soc | 2011 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/21247159 |
A force balance can explain local and global cell movements during early zebrafish development. | Chai J, Hamilton AL, Krieg M, Buckley CD, Riedel-Kruse IH, Dunn AR | Biophysical journal | 26200877 | Biophys J | 2015 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/26200877 |
Visualizing the interior architecture of focal adhesions with high-resolution traction maps. | Morimatsu M, Mekhdjian AH, Chang AC, Tan SJ, Dunn AR | Nano letters | 25730141 | Nano Lett | 2015 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/25730141 |
Spatial distribution of cell-cell and cell-ECM adhesions regulates force balance while main-taining E-cadherin molecular tension in cell pairs. | Sim JY, Moeller J, Hart KC, Ramallo D, Vogel V, Dunn AR, Nelson WJ, Pruitt BL | Molecular biology of the cell | 25971797 | Mol Biol Cell | 2015 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/25971797 |
Iron addiction: a novel therapeutic target in ovarian cancer. | Basuli D, Tesfay L, Deng Z, Paul B, Yamamoto Y, Ning G, Xian W, McKeon F, Lynch M, Crum CP, Hegde P, Brewer M, Wang X, Miller LD, Dyment N, Torti FM, Torti SV | Oncogene | 28319068 | Oncogene | 2017 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/28319068 |
Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis. | Dai C, Santagata S, Tang Z, Shi J, Cao J, Kwon H, Bronson RT, Whitesell L, Lindquist S | The Journal of clinical investigation | 22945628 | J Clin Invest | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22945628 |
Metabolic stressors disrupt proteome homeostasis to suppress malignancy. | Dai C | Molecular & cellular oncology | 26973866 | Mol Cell Oncol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26973866 |
HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. | Su KH, Cao J, Tang Z, Dai S, He Y, Sampson SB, Benjamin IJ, Dai C | Nature cell biology | 27043084 | Nat Cell Biol | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27043084 |
HSF1 physically neutralizes amyloid oligomers to empower overgrowth and bestow neuroprotection. | Tang Z, Su KH, Xu M, Dai C | Science advances | 33177089 | Sci Adv | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33177089 |
MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1. | Tang Z, Dai S, He Y, Doty RA, Shultz LD, Sampson SB, Dai C | Cell | 25679764 | Cell | 2015 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/25679764 |
HSF1: Guardian of Proteostasis in Cancer. | Dai C, Sampson SB | Trends in cell biology | 26597576 | Trends Cell Biol | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/26597576 |
Visualization of RAS/MAPK Signaling In Situ by the Proximity Ligation Assay (PLA). | Tang Z, Dai C | Methods in molecular biology (Clifton, N.J.) | 27924568 | Methods Mol Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/27924568 |
Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK. | Dai S, Tang Z, Cao J, Zhou W, Li H, Sampson S, Dai C | The EMBO journal | 25425574 | EMBO J | 2015 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/25425574 |
Proteotoxic stress of cancer: implication of the heat-shock response in oncogenesis. | Dai C, Dai S, Cao J | Journal of cellular physiology | 22105155 | J Cell Physiol | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22105155 |
Metabolic control of the proteotoxic stress response: implications in diabetes mellitus and neurodegenerative disorders. | Su KH, Dai C | Cellular and molecular life sciences : CMLS | 27289378 | Cell Mol Life Sci | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27289378 |
Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response. | Xu M, Lin L, Ram BM, Shriwas O, Chuang KH, Dai S, Su KH, Tang Z, Dai C | Cell reports | 37224019 | Cell Rep | 2023 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/37224019 |
Manganese binding properties of human calprotectin under conditions of high and low calcium: X-ray crystallographic and advanced electron paramagnetic resonance spectroscopic analysis. | Gagnon DM, Brophy MB, Bowman SE, Stich TA, Drennan CL, Britt RD, Nolan EM | Journal of the American Chemical Society | 25597447 | J Am Chem Soc | 2015 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/25597447 |
Reduction of human defensin 5 affords a high-affinity zinc-chelating peptide. | Zhang Y, Cougnon FB, Wanniarachchi YA, Hayden JA, Nolan EM | ACS chemical biology | 23841778 | ACS Chem Biol | 2013 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/23841778 |
Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247. | Shabab M, Arnold MF, Penterman J, Wommack AJ, Bocker HT, Price PA, Griffitts JS, Nolan EM, Walker GC | Proceedings of the National Academy of Sciences of the United States of America | 27551097 | Proc Natl Acad Sci U S A | 2016 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/27551097 |
A bacterial mutant library as a tool to study the attack of a defensin peptide. | Moser S, Chileveru HR, Tomaras J, Nolan EM | Chembiochem : a European journal of chemical biology | 25430675 | Chembiochem | 2014 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/25430675 |
Human defensin 5 disulfide array mutants: disulfide bond deletion attenuates antibacterial activity against Staphylococcus aureus. | Wanniarachchi YA, Kaczmarek P, Wan A, Nolan EM | Biochemistry | 21861459 | Biochemistry | 2011 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/21861459 |
Discovery and characterization of a disulfide-locked C(2)-symmetric defensin peptide. | Wommack AJ, Ziarek JJ, Tomaras J, Chileveru HR, Zhang Y, Wagner G, Nolan EM | Journal of the American Chemical Society | 25181039 | J Am Chem Soc | 2014 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/25181039 |
Human α-Defensin 6: A Small Peptide That Self-Assembles and Protects the Host by Entangling Microbes. | Chairatana P, Nolan EM | Accounts of chemical research | 28296382 | Acc Chem Res | 2017 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/28296382 |
Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut. | Chairatana P, Nolan EM | Critical reviews in biochemistry and molecular biology | 27841019 | Crit Rev Biochem Mol Biol | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/27841019 |
Visualizing attack of Escherichia coli by the antimicrobial peptide human defensin 5. | Chileveru HR, Lim SA, Chairatana P, Wommack AJ, Chiang IL, Nolan EM | Biochemistry | 25664683 | Biochemistry | 2015 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/25664683 |
Human calprotectin is an iron-sequestering host-defense protein. | Nakashige TG, Zhang B, Krebs C, Nolan EM | Nature chemical biology | 26302479 | Nat Chem Biol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26302479 |
Calcium ion gradients modulate the zinc affinity and antibacterial activity of human calprotectin. | Brophy MB, Hayden JA, Nolan EM | Journal of the American Chemical Society | 23082970 | J Am Chem Soc | 2012 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/23082970 |
NMR solution structure and condition-dependent oligomerization of the antimicrobial peptide human defensin 5. | Wommack AJ, Robson SA, Wanniarachchi YA, Wan A, Turner CJ, Wagner G, Nolan EM | Biochemistry | 23163963 | Biochemistry | 2012 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/23163963 |
Calcium Ions Tune the Zinc-Sequestering Properties and Antimicrobial Activity of Human S100A12. | Cunden LS, Gaillard A, Nolan EM | Chemical science | 26913170 | Chem Sci | 2016 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/26913170 |
Manganese and microbial pathogenesis: sequestration by the Mammalian immune system and utilization by microorganisms. | Brophy MB, Nolan EM | ACS chemical biology | 25594606 | ACS Chem Biol | 2015 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/25594606 |
Calcium-induced Tetramerization and Zinc Chelation Shield Human Calprotectin from Degradation by Host and Bacterial Extracellular Proteases. | Stephan JR, Nolan EM | Chemical science | 26925211 | Chem Sci | 2016 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26925211 |
Proteolysis Triggers Self-Assembly and Unmasks Innate Immune Function of a Human α-Defensin Peptide. | Chairatana P, Chu H, Castillo PA, Shen B, Bevins CL, Nolan EM | Chemical science | 27076903 | Chem Sci | 2016 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/27076903 |
Molecular basis for self-assembly of a human host-defense peptide that entraps bacterial pathogens. | Chairatana P, Nolan EM | Journal of the American Chemical Society | 25158166 | J Am Chem Soc | 2014 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/25158166 |
The Hexahistidine Motif of Host-Defense Protein Human Calprotectin Contributes to Zinc Withholding and Its Functional Versatility. | Nakashige TG, Stephan JR, Cunden LS, Brophy MB, Wommack AJ, Keegan BC, Shearer JM, Nolan EM | Journal of the American Chemical Society | 27541598 | J Am Chem Soc | 2016 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/27541598 |
Morphometry-based measurements of the structural response to whole-brain radiation. | Fuentes D, Contreras J, Yu J, He R, Castillo E, Castillo R, Guerrero T | International journal of computer assisted radiology and surgery | 25408306 | Int J Comput Assist Radiol Surg | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25408306 |
Pre-Radiation Therapy Fluorine 18 Fluorodeoxyglucose PET Helps Identify Patients with Esophageal Cancer at High Risk for Radiation Pneumonitis. | Castillo R, Pham N, Castillo E, Aso-Gonzalez S, Ansari S, Hobbs B, Palacio D, Skinner H, Guerrero TM | Radiology | 25584706 | Radiology | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25584706 |
Clinical validation of 4-dimensional computed tomography ventilation with pulmonary function test data. | Brennan D, Schubert L, Diot Q, Castillo R, Castillo E, Guerrero T, Martel MK, Linderman D, Gaspar LE, Miften M, Kavanagh BD, Vinogradskiy Y | International journal of radiation oncology, biology, physics | 25817531 | Int J Radiat Oncol Biol Phys | 2015 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/25817531 |
Computing global minimizers to a constrained B-spline image registration problem from optimal l1 perturbations to block match data. | Castillo E, Castillo R, Fuentes D, Guerrero T | Medical physics | 24694135 | Med Phys | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24694135 |
Results of a Multi-Institutional Phase 2 Clinical Trial for 4DCT-Ventilation Functional Avoidance Thoracic Radiation Therapy. | Vinogradskiy Y, Castillo R, Castillo E, Schubert L, Jones BL, Faught A, Gaspar LE, Kwak J, Bowles DW, Waxweiler T, Dougherty JM, Gao D, Stevens C, Miften M, Kavanagh B, Grills I, Rusthoven CG, Guerrero T | International journal of radiation oncology, biology, physics | 34767934 | Int J Radiat Oncol Biol Phys | 2022 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/34767934 |
Pre-radiotherapy FDG PET predicts radiation pneumonitis in lung cancer. | Castillo R, Pham N, Ansari S, Meshkov D, Castillo S, Li M, Olanrewaju A, Hobbs B, Castillo E, Guerrero T | Radiation oncology (London, England) | 24625207 | Radiat Oncol | 2014 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/24625207 |
Evaluation of image registration spatial accuracy using a Bayesian hierarchical model. | Liu S, Yuan Y, Castillo R, Guerrero T, Johnson VE | Biometrics | 24575781 | Biometrics | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24575781 |
A reference dataset for deformable image registration spatial accuracy evaluation using the COPDgene study archive. | Castillo R, Castillo E, Fuentes D, Ahmad M, Wood AM, Ludwig MS, Guerrero T | Physics in medicine and biology | 23571679 | Phys Med Biol | 2013 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/23571679 |
Least median of squares filtering of locally optimal point matches for compressible flow image registration. | Castillo E, Castillo R, White B, Rojo J, Guerrero T | Physics in medicine and biology | 22797602 | Phys Med Biol | 2012 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/22797602 |
Modeling lung deformation: a combined deformable image registration method with spatially varying Young's modulus estimates. | Li M, Castillo E, Zheng XL, Luo HY, Castillo R, Wu Y, Guerrero T | Medical physics | 23927316 | Med Phys | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23927316 |
Spatial correspondence of 4D CT ventilation and SPECT pulmonary perfusion defects in patients with malignant airway stenosis. | Castillo R, Castillo E, McCurdy M, Gomez DR, Block AM, Bergsma D, Joy S, Guerrero T | Physics in medicine and biology | 22411124 | Phys Med Biol | 2012 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/22411124 |
Deformable image registration for temporal subtraction of chest radiographs. | Li M, Castillo E, Luo HY, Zheng XL, Castillo R, Meshkov D, Guerrero T | International journal of computer assisted radiology and surgery | 24078349 | Int J Comput Assist Radiol Surg | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24078349 |
Comparison of 4-dimensional computed tomography ventilation with nuclear medicine ventilation-perfusion imaging: a clinical validation study. | Vinogradskiy Y, Koo PJ, Castillo R, Castillo E, Guerrero T, Gaspar LE, Miften M, Kavanagh BD | International journal of radiation oncology, biology, physics | 24725702 | Int J Radiat Oncol Biol Phys | 2014 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/24725702 |
Assessment of a quantitative metric for 4D CT artifact evaluation by observer consensus. | Castillo SJ, Castillo R, Balter P, Pan T, Ibbott G, Hobbs B, Yuan Y, Guerrero T | Journal of applied clinical medical physics | 24892346 | J Appl Clin Med Phys | 2014 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/24892346 |
Proton therapy radiation pneumonitis local dose-response in esophagus cancer patients. | Echeverria AE, McCurdy M, Castillo R, Bernard V, Ramos NV, Buckley W, Castillo E, Liu P, Martinez J, Guerrero T | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | 23127772 | Radiother Oncol | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23127772 |
Use of 4-dimensional computed tomography-based ventilation imaging to correlate lung dose and function with clinical outcomes. | Vinogradskiy Y, Castillo R, Castillo E, Tucker SL, Liao Z, Guerrero T, Martel MK | International journal of radiation oncology, biology, physics | 23474113 | Int J Radiat Oncol Biol Phys | 2013 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/23474113 |
Quality assurance assessment of diagnostic and radiation therapy-simulation CT image registration for head and neck radiation therapy: anatomic region of interest-based comparison of rigid and deformable algorithms. | Mohamed AS, Ruangskul MN, Awan MJ, Baron CA, Kalpathy-Cramer J, Castillo R, Castillo E, Guerrero TM, Kocak-Uzel E, Yang J, Court LE, Kantor ME, Gunn GB, Colen RR, Frank SJ, Garden AS, Rosenthal DI, Fuller CD | Radiology | 25380454 | Radiology | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25380454 |
Evaluation of 4D CT acquisition methods designed to reduce artifacts. | Castillo SJ, Castillo R, Castillo E, Pan T, Ibbott G, Balter P, Hobbs B, Guerrero T | Journal of applied clinical medical physics | 26103169 | J Appl Clin Med Phys | 2015 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/26103169 |
Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes. | Levy H, Wang X, Kaldunski M, Jia S, Kramer J, Pavletich SJ, Reske M, Gessel T, Yassai M, Quasney MW, Dahmer MK, Gorski J, Hessner MJ | Genes and immunity | 22972474 | Genes Immun | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22972474 |
Changing incidence of cystic fibrosis in Wisconsin, USA. | Parker-McGill K, Nugent M, Bersie R, Hoffman G, Rock M, Baker M, Farrell PM, Simpson P, Levy H | Pediatric pulmonology | 26258862 | Pediatr Pulmonol | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26258862 |
Variants in Solute Carrier SLC26A9 Modify Prenatal Exocrine Pancreatic Damage in Cystic Fibrosis. | Miller MR, Soave D, Li W, Gong J, Pace RG, Boëlle PY, Cutting GR, Drumm ML, Knowles MR, Sun L, Rommens JM, Accurso F, Durie PR, Corvol H, Levy H, Sontag MK, Strug LJ | The Journal of pediatrics | 25771386 | J Pediatr | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25771386 |
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Comparison of WHO and CDC growth charts in predicting pulmonary outcomes in cystic fibrosis. | Machogu E, Cao Y, Miller T, Simpson P, Levy H, Quintero D, Goday PS | Journal of pediatric gastroenterology and nutrition | 25714581 | J Pediatr Gastroenterol Nutr | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25714581 |
Cystic fibrosis mutations for p.F508del compound heterozygotes predict sweat chloride levels and pancreatic sufficiency. | Sebro R, Levy H, Schneck K, Dimmock D, Raby BA, Cannon CL, Broeckel U, Risch NJ | Clinical genetics | 22035343 | Clin Genet | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22035343 |
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Risk factors for the progression of cystic fibrosis lung disease throughout childhood. | Sanders DB, Li Z, Laxova A, Rock MJ, Levy H, Collins J, Ferec C, Farrell PM | Annals of the American Thoracic Society | 24261460 | Ann Am Thorac Soc | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24261460 |
Transcriptional consequences of impaired immune cell responses induced by cystic fibrosis plasma characterized via dual RNA sequencing. | Ideozu JE, Rangaraj V, Abdala-Valencia H, Zhang X, Kandpal M, Sala MA, Davuluri RV, Levy H | BMC medical genomics | 31118097 | BMC Med Genomics | 2019 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/31118097 |
Increased Expression of Plasma-Induced ABCC1 mRNA in Cystic Fibrosis. | Ideozu JE, Zhang X, Pan A, Ashrafi Z, Woods KJ, Hessner MJ, Simpson P, Levy H | International journal of molecular sciences | 28800122 | Int J Mol Sci | 2017 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/28800122 |
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Refining the continuum of CFTR-associated disorders in the era of newborn screening. | Levy H, Nugent M, Schneck K, Stachiw-Hietpas D, Laxova A, Lakser O, Rock M, Dahmer MK, Biller J, Nasr SZ, Baker M, McColley SA, Simpson P, Farrell PM | Clinical genetics | 26671754 | Clin Genet | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26671754 |
CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons. | Zhang X, Moore CM, Harmacek LD, Domenico J, Rangaraj VR, Ideozu JE, Knapp JR, Woods KJ, Jump S, Jia S, Prokop JW, Bowler R, Hessner MJ, Gelfand EW, Levy H | JCI insight | 35315363 | JCI Insight | 2022 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/35315363 |
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New challenges in the diagnosis and management of cystic fibrosis. | Levy H, Farrell PM | The Journal of pediatrics | 26008169 | J Pediatr | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26008169 |
Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy. | Beraldi R, Li X, Martinez Fernandez A, Reyes S, Secreto F, Terzic A, Olson TM, Nelson TJ | Human molecular genetics | 24584570 | Hum Mol Genet | 2014 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/24584570 |
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Human umbilical cord blood-derived mononuclear cells improve murine ventricular function upon intramyocardial delivery in right ventricular chronic pressure overload. | Oommen S, Yamada S, Cantero Peral S, Campbell KA, Bruinsma ES, Terzic A, Nelson TJ | Stem cell research & therapy | 25890300 | Stem Cell Res Ther | 2015 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/25890300 |
Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines. | Martinez-Fernandez A, Li X, Hartjes KA, Terzic A, Nelson TJ | Circulation. Cardiovascular genetics | 24036272 | Circ Cardiovasc Genet | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24036272 |
Disease-causing mitochondrial heteroplasmy segregated within induced pluripotent stem cell clones derived from a patient with MELAS. | Folmes CD, Martinez-Fernandez A, Perales-Clemente E, Li X, McDonald A, Oglesbee D, Hrstka SC, Perez-Terzic C, Terzic A, Nelson TJ | Stem cells (Dayton, Ohio) | 23553816 | Stem Cells | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23553816 |
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Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient-Derived iPSC Model. | Wyles SP, Hrstka SC, Reyes S, Terzic A, Olson TM, Nelson TJ | Clinical and translational science | 27105042 | Clin Transl Sci | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27105042 |
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Inhibition of DNA topoisomerase II selectively reduces the threat of tumorigenicity following induced pluripotent stem cell-based myocardial therapy. | Wyles SP, Yamada S, Oommen S, Maleszewski JJ, Beraldi R, Martinez-Fernandez A, Terzic A, Nelson TJ | Stem cells and development | 25036735 | Stem Cells Dev | 2014 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/25036735 |
Transcriptional atlas of cardiogenesis maps congenital heart disease interactome. | Li X, Martinez-Fernandez A, Hartjes KA, Kocher JP, Olson TM, Terzic A, Nelson TJ | Physiological genomics | 24803680 | Physiol Genomics | 2014 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/24803680 |
Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability. | Perales-Clemente E, Cook AN, Evans JM, Roellinger S, Secreto F, Emmanuele V, Oglesbee D, Mootha VK, Hirano M, Schon EA, Terzic A, Nelson TJ | The EMBO journal | 27436875 | EMBO J | 2016 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/27436875 |
Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cells. | Wyles SP, Li X, Hrstka SC, Reyes S, Oommen S, Beraldi R, Edwards J, Terzic A, Olson TM, Nelson TJ | Human molecular genetics | 26604136 | Hum Mol Genet | 2016 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/26604136 |
Selection via pluripotency-related transcriptional screen minimizes the influence of somatic origin on iPSC differentiation propensity. | Hartjes KA, Li X, Martinez-Fernandez A, Roemmich AJ, Larsen BT, Terzic A, Nelson TJ | Stem cells (Dayton, Ohio) | 24802033 | Stem Cells | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/24802033 |
Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discovery. | Campbell KA, Terzic A, Nelson TJ | Regenerative medicine | 26439809 | Regen Med | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26439809 |
Systems-based technologies in profiling the stem cell molecular framework for cardioregenerative medicine. | Wyles SP, Faustino RS, Li X, Terzic A, Nelson TJ | Stem cell reviews and reports | 25218144 | Stem Cell Rev Rep | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25218144 |
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Cell-autonomous regulation of brown fat identity gene UCP1 by unliganded vitamin D receptor. | Malloy PJ, Feldman BJ | Molecular endocrinology (Baltimore, Md.) | 23906633 | Mol Endocrinol | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23906633 |
A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes. | Zhang B, Kumar RB, Dai H, Feldman BJ | Nature medicine | 25038825 | Nat Med | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/25038825 |
Tumor Autonomous Effects of Vitamin D Deficiency Promote Breast Cancer Metastasis. | Williams JD, Aggarwal A, Swami S, Krishnan AV, Ji L, Albertelli MA, Feldman BJ | Endocrinology | 26934299 | Endocrinology | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26934299 |
A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo. | Wong JC, Krueger KC, Costa MJ, Aggarwal A, Du H, McLaughlin TL, Feldman BJ | Science signaling | 27811141 | Sci Signal | 2016 Oct 25 | https://www.ncbi.nlm.nih.gov/pubmed/27811141 |
Adipose circadian clocks: coordination of metabolic rhythms by clock genes, steroid hormones, and PPARs. | Krueger KC, Feldman BJ | Hormone molecular biology and clinical investigation | 25436716 | Horm Mol Biol Clin Investig | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/25436716 |
Vitamin D Regulates Fatty Acid Composition in Subcutaneous Adipose Tissue Through Elovl3. | Ji L, Gupta M, Feldman BJ | Endocrinology | 26488808 | Endocrinology | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/26488808 |
Circadian rhythm gene period 3 is an inhibitor of the adipocyte cell fate. | Costa MJ, So AY, Kaasik K, Krueger KC, Pillsbury ML, Fu YH, Ptacek LJ, Yamamoto KR, Feldman BJ | The Journal of biological chemistry | 21228270 | J Biol Chem | 2011 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/21228270 |
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The development of next-generation screening and diagnostic platforms will change diabetes care. | Kumar RB, Gupta M, Feldman BJ | Expert review of molecular diagnostics | 25583407 | Expert Rev Mol Diagn | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25583407 |
Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice. | Ota A, Kovary KM, Wu OH, Ahrends R, Shen WJ, Costa MJ, Feldman BJ, Kraemer FB, Teruel MN | Journal of lipid research | 25840986 | J Lipid Res | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25840986 |
BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension. | Diebold I, Hennigs JK, Miyagawa K, Li CG, Nickel NP, Kaschwich M, Cao A, Wang L, Reddy S, Chen PI, Nakahira K, Alcazar MA, Hopper RK, Ji L, Feldman BJ, Rabinovitch M | Cell metabolism | 25863249 | Cell Metab | 2015 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/25863249 |
Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D. | Jeong Y, Swami S, Krishnan AV, Williams JD, Martin S, Horst RL, Albertelli MA, Feldman BJ, Feldman D, Diehn M | Molecular cancer therapeutics | 25934710 | Mol Cancer Ther | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/25934710 |
Macrophage-released ADAMTS1 promotes muscle stem cell activation. | Du H, Shih CH, Wosczyna MN, Mueller AA, Cho J, Aggarwal A, Rando TA, Feldman BJ | Nature communications | 28939843 | Nat Commun | 2017 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/28939843 |
The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15. | Aggarwal A, Costa MJ, Rivero-Gutiérrez B, Ji L, Morgan SL, Feldman BJ | Cell reports | 29186676 | Cell Rep | 2017 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/29186676 |
The Low Noise Limit in Gene Expression. | Dar RD, Razooky BS, Weinberger LS, Cox CD, Simpson ML | PloS one | 26488303 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26488303 |
Feedback-mediated signal conversion promotes viral fitness. | Vardi N, Chaturvedi S, Weinberger LS | Proceedings of the National Academy of Sciences of the United States of America | 30150412 | Proc Natl Acad Sci U S A | 2018 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/30150412 |
Post-Transcriptional Noise Control. | Hansen MMK, Weinberger LS | BioEssays : news and reviews in molecular, cellular and developmental biology | 31222776 | Bioessays | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31222776 |
Cytoplasmic Amplification of Transcriptional Noise Generates Substantial Cell-to-Cell Variability. | Hansen MMK, Desai RV, Simpson ML, Weinberger LS | Cell systems | 30243562 | Cell Syst | 2018 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/30243562 |
A minimal fate-selection switch. | Weinberger LS | Current opinion in cell biology | 26611210 | Curr Opin Cell Biol | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26611210 |
A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization. | Hansen MMK, Wen WY, Ingerman E, Razooky BS, Thompson CE, Dar RD, Chin CW, Simpson ML, Weinberger LS | Cell | 29754821 | Cell | 2018 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/29754821 |
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Screening for noise in gene expression identifies drug synergies. | Dar RD, Hosmane NN, Arkin MR, Siliciano RF, Weinberger LS | Science (New York, N.Y.) | 24903562 | Science | 2014 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/24903562 |
RanDeL-Seq: a High-Throughput Method to Map Viral cis- and trans-Acting Elements. | Notton T, Glazier JJ, Saykally VR, Thompson CE, Weinberger LS | mBio | 33468683 | mBio | 2021 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/33468683 |
Transcriptional burst frequency and burst size are equally modulated across the human genome. | Dar RD, Razooky BS, Singh A, Trimeloni TV, McCollum JM, Cox CD, Simpson ML, Weinberger LS | Proceedings of the National Academy of Sciences of the United States of America | 23064634 | Proc Natl Acad Sci U S A | 2012 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/23064634 |
Dynamics of protein noise can distinguish between alternate sources of gene-expression variability. | Singh A, Razooky BS, Dar RD, Weinberger LS | Molecular systems biology | 22929617 | Mol Syst Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22929617 |
Microwell devices with finger-like channels for long-term imaging of HIV-1 expression kinetics in primary human lymphocytes. | Razooky BS, Gutierrez E, Terry VH, Spina CA, Groisman A, Weinberger LS | Lab on a chip | 22976503 | Lab Chip | 2012 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/22976503 |
A molecular mechanism for probabilistic bet hedging and its role in viral latency. | Chaturvedi S, Klein J, Vardi N, Bolovan-Fritts C, Wolf M, Du K, Mlera L, Calvert M, Moorman NJ, Goodrum F, Huang B, Weinberger LS | Proceedings of the National Academy of Sciences of the United States of America | 32632017 | Proc Natl Acad Sci U S A | 2020 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/32632017 |
A Bioreactor Method to Generate High-titer, Genetically Stable, Clinical-isolate Human Cytomegalovirus. | Saykally VR, Rast LI, Sasaki J, Jung SY, Bolovan-Fritts C, Weinberger LS | Bio-protocol | 29226181 | Bio Protoc | 2017 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/29226181 |
Transient Thresholding: A Mechanism Enabling Noncooperative Transcriptional Circuitry to Form a Switch. | Aull KH, Tanner EJ, Thomson M, Weinberger LS | Biophysical journal | 28591615 | Biophys J | 2017 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/28591615 |
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Disrupting autorepression circuitry generates "open-loop lethality" to yield escape-resistant antiviral agents. | Chaturvedi S, Pablo M, Wolf M, Rosas-Rivera D, Calia G, Kumar AJ, Vardi N, Du K, Glazier J, Ke R, Chan MF, Perelson AS, Weinberger LS | Cell | 35561685 | Cell | 2022 Jun 9 | https://www.ncbi.nlm.nih.gov/pubmed/35561685 |
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Mapping the architecture of the HIV-1 Tat circuit: A decision-making circuit that lacks bistability and exploits stochastic noise. | Razooky BS, Weinberger LS | Methods (San Diego, Calif.) | 21167940 | Methods | 2011 Jan | https://www.ncbi.nlm.nih.gov/pubmed/21167940 |
The HSV-1 ICP4 Transcriptional Auto-Repression Circuit Functions as a Transcriptional "Accelerator" Circuit. | Chaturvedi S, Engel R, Weinberger L | Frontiers in cellular and infection microbiology | 32670890 | Front Cell Infect Microbiol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32670890 |
Engineered deletions of HIV replicate conditionally to reduce disease in nonhuman primates. | Pitchai FNN, Tanner EJ, Khetan N, Vasen G, Levrel C, Kumar AJ, Pandey S, Ordonez T, Barnette P, Spencer D, Jung SY, Glazier J, Thompson C, Harvey-Vera A, Son HI, Son HI, Strathdee SA, Holguin L, Urak R, Burnett J, Burgess W, Busman-Sahay K, Estes JD, Hessell A, Fennessey CM, Keele BF, Haigwood NL, Weinberger LS | Science (New York, N.Y.) | 39116226 | Science | 2024 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/39116226 |
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High-Throughput Microfluidic Labyrinth for the Label-free Isolation of Circulating Tumor Cells. | Lin E, Rivera-Báez L, Fouladdel S, Yoon HJ, Guthrie S, Wieger J, Deol Y, Keller E, Sahai V, Simeone DM, Burness ML, Azizi E, Wicha MS, Nagrath S | Cell systems | 28941584 | Cell Syst | 2017 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/28941584 |
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Detection of CTC Clusters and a Dedifferentiated RNA-Expression Survival Signature in Prostate Cancer. | Kozminsky M, Fouladdel S, Chung JS, Wang Y, Smith DC, Alva A, Azizi E, Morgan T, Nagrath S | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 30693182 | Adv Sci (Weinh) | 2019 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/30693182 |
A radial flow microfluidic device for ultra-high-throughput affinity-based isolation of circulating tumor cells. | Murlidhar V, Zeinali M, Grabauskiene S, Ghannad-Rezaie M, Wicha MS, Simeone DM, Ramnath N, Reddy RM, Nagrath S | Small (Weinheim an der Bergstrasse, Germany) | 25074448 | Small | 2014 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/25074448 |
Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes. | Kanwar SS, Dunlay CJ, Simeone DM, Nagrath S | Lab on a chip | 24722878 | Lab Chip | 2014 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/24722878 |
Expanded Circulating Tumor Cells from a Patient with ALK-Positive Lung Cancer Present with EML4-ALK Rearrangement Along with Resistance Mutation and Enable Drug Sensitivity Testing: A Case Study. | Zhang Z, Shiratsuchi H, Palanisamy N, Nagrath S, Ramnath N | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer | 27507192 | J Thorac Oncol | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/27507192 |
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Pulmonary venous blood sampling significantly increases the yield of circulating tumor cells in early-stage lung cancer. | Reddy RM, Murlidhar V, Zhao L, Grabauskiene S, Zhang Z, Ramnath N, Lin J, Chang AC, Carrott P, Lynch W, Orringer MB, Beer DG, Nagrath S | The Journal of thoracic and cardiovascular surgery | 26614417 | J Thorac Cardiovasc Surg | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26614417 |
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An empirical analysis of White privilege, social position and health. | Kwate NO, Goodman MS | Social science & medicine (1982) | 25014267 | Soc Sci Med | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25014267 |
Racism at the intersections: Gender and socioeconomic differences in the experience of racism among African Americans. | Kwate NO, Goodman MS | The American journal of orthopsychiatry | 26460700 | Am J Orthopsychiatry | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26460700 |
Perceiving the Black female body: Race and gender in police constructions of body weight. | Kwate NO, Threadcraft S | Race and social problems | 26478750 | Race Soc Probl | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26478750 |
"Racism still exists": a public health intervention using racism "countermarketing" outdoor advertising in a Black neighborhood. | Kwate NO | Journal of urban health : bulletin of the New York Academy of Medicine | 24849616 | J Urban Health | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24849616 |
Does learning about race prevent substance abuse? Racial discrimination, racial socialization and substance use among African Americans. | Thompson AB, Goodman MS, Kwate NO | Addictive behaviors | 27182620 | Addict Behav | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27182620 |
MyD88 and retinoic acid signaling pathways interact to modulate gastrointestinal activities of dendritic cells. | Villablanca EJ, Wang S, de Calisto J, Gomes DC, Kane MA, Napoli JL, Blaner WS, Kagechika H, Blomhoff R, Rosemblatt M, Bono MR, von Andrian UH, Mora JR | Gastroenterology | 21596042 | Gastroenterology | 2011 Jul | https://www.ncbi.nlm.nih.gov/pubmed/21596042 |
Blocking lymphocyte localization to the gastrointestinal mucosa as a therapeutic strategy for inflammatory bowel diseases. | Villablanca EJ, Cassani B, von Andrian UH, Mora JR | Gastroenterology | 21530744 | Gastroenterology | 2011 May | https://www.ncbi.nlm.nih.gov/pubmed/21530744 |
MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties. | Wang S, Villablanca EJ, De Calisto J, Gomes DC, Nguyen DD, Mizoguchi E, Kagan JC, Reinecker HC, Hacohen N, Nagler C, Xavier RJ, Rossi-Bergmann B, Chen YB, Blomhoff R, Snapper SB, Mora JR | Journal of immunology (Baltimore, Md. : 1950) | 21646294 | J Immunol | 2011 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/21646294 |
Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice. | Cassani B, Villablanca EJ, Quintana FJ, Love PE, Lacy-Hulbert A, Blaner WS, Sparwasser T, Snapper SB, Weiner HL, Mora JR | Gastroenterology | 21925467 | Gastroenterology | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21925467 |
Clinical assessment incorporating a personal genome. | Ashley EA, Butte AJ, Wheeler MT, Chen R, Klein TE, Dewey FE, Dudley JT, Ormond KE, Pavlovic A, Morgan AA, Pushkarev D, Neff NF, Hudgins L, Gong L, Hodges LM, Berlin DS, Thorn CF, Sangkuhl K, Hebert JM, Woon M, Sagreiya H, Whaley R, Knowles JW, Chou MF, Thakuria JV, Rosenbaum AM, Zaranek AW, Church GM, Greely HT, Quake SR, Altman RB | Lancet (London, England) | 20435227 | Lancet | 2010 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/20435227 |
Cardiac structural and sarcomere genes associated with cardiomyopathy exhibit marked intolerance of genetic variation. | Pan S, Caleshu CA, Dunn KE, Foti MJ, Moran MK, Soyinka O, Ashley EA | Circulation. Cardiovascular genetics | 23074333 | Circ Cardiovasc Genet | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23074333 |
Molecular diagnosis of long QT syndrome at 10 days of life by rapid whole genome sequencing. | Priest JR, Ceresnak SR, Dewey FE, Malloy-Walton LE, Dunn K, Grove ME, Perez MV, Maeda K, Dubin AM, Ashley EA | Heart rhythm | 24973560 | Heart Rhythm | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24973560 |
Gene coexpression network topology of cardiac development, hypertrophy, and failure. | Dewey FE, Perez MV, Wheeler MT, Watt C, Spin J, Langfelder P, Horvath S, Hannenhalli S, Cappola TP, Ashley EA | Circulation. Cardiovascular genetics | 21127201 | Circ Cardiovasc Genet | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/21127201 |
Early somatic mosaicism is a rare cause of long-QT syndrome. | Priest JR, Gawad C, Kahlig KM, Yu JK, O'Hara T, Boyle PM, Rajamani S, Clark MJ, Garcia ST, Ceresnak S, Harris J, Boyle S, Dewey FE, Malloy-Walton L, Dunn K, Grove M, Perez MV, Neff NF, Chen R, Maeda K, Dubin A, Belardinelli L, West J, Antolik C, Macaya D, Quertermous T, Trayanova NA, Quake SR, Ashley EA | Proceedings of the National Academy of Sciences of the United States of America | 27681629 | Proc Natl Acad Sci U S A | 2016 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/27681629 |
Neuronal pentraxins mediate silent synapse conversion in the developing visual system. | Koch SM, Ullian EM | The Journal of neuroscience : the official journal of the Society for Neuroscience | 20392962 | J Neurosci | 2010 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/20392962 |
Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. | Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, Madireddy L, Chan JR, Baranzini SE, Ullian EM, Rowitch DH | Nature | 24776795 | Nature | 2014 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/24776795 |
A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies. | Krencik R, Ullian EM | Frontiers in cellular neuroscience | 23503583 | Front Cell Neurosci | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23503583 |
Correlation of outer nuclear layer thickness with cone density values in patients with retinitis pigmentosa and healthy subjects. | Menghini M, Lujan BJ, Zayit-Soudry S, Syed R, Porco TC, Bayabo K, Carroll J, Roorda A, Duncan JL | Investigative ophthalmology & visual science | 25515570 | Invest Ophthalmol Vis Sci | 2014 Dec 16 | https://www.ncbi.nlm.nih.gov/pubmed/25515570 |
Extracellular metabolic energetics can promote cancer progression. | Loo JM, Scherl A, Nguyen A, Man FY, Weinberg E, Zeng Z, Saltz L, Paty PB, Tavazoie SF | Cell | 25601461 | Cell | 2015 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/25601461 |
PKLR promotes colorectal cancer liver colonization through induction of glutathione synthesis. | Nguyen A, Loo JM, Mital R, Weinberg EM, Man FY, Zeng Z, Paty PB, Saltz L, Janjigian YY, de Stanchina E, Tavazoie SF | The Journal of clinical investigation | 26784545 | J Clin Invest | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26784545 |
Control of metastatic progression by microRNA regulatory networks. | Pencheva N, Tavazoie SF | Nature cell biology | 23728460 | Nat Cell Biol | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23728460 |
Radially branched deployment for more efficient cell transplantation at the scale of the human brain. | Silvestrini MT, Yin D, Coppes VG, Mann P, Martin AJ, Larson PS, Starr PA, Gupta N, Panter SS, Desai TA, Lim DA | Stereotactic and functional neurosurgery | 23343609 | Stereotact Funct Neurosurg | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23343609 |
The Ink4a/Arf locus is a barrier to direct neuronal transdifferentiation. | Price JD, Park KY, Chen J, Salinas RD, Cho MJ, Kriegstein AR, Lim DA | The Journal of neuroscience : the official journal of the Society for Neuroscience | 25209293 | J Neurosci | 2014 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/25209293 |
Analysis of Mll1 deficiency identifies neurogenic transcriptional modules and Brn4 as a factor for direct astrocyte-to-neuron reprogramming. | Potts MB, Siu JJ, Price JD, Salinas RD, Cho MJ, Ramos AD, Hahn J, Margeta M, Oldham MC, Lim DA | Neurosurgery | 24887289 | Neurosurgery | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24887289 |
Embryonic Nkx2.1-expressing neural precursor cells contribute to the regional heterogeneity of adult V-SVZ neural stem cells. | Delgado RN, Lim DA | Developmental biology | 26387477 | Dev Biol | 2015 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/26387477 |
Maintenance of neural stem cell positional identity by mixed-lineage leukemia 1. | Delgado RN, Mansky B, Ahanger SH, Lu C, Andersen RE, Dou Y, Alvarez-Buylla A, Lim DA | Science (New York, N.Y.) | 32241942 | Science | 2020 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/32241942 |
Distinct and separable roles for EZH2 in neurogenic astroglia. | Hwang WW, Salinas RD, Siu JJ, Kelley KW, Delgado RN, Paredes MF, Alvarez-Buylla A, Oldham MC, Lim DA | eLife | 24867641 | Elife | 2014 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/24867641 |
Interventional magnetic resonance imaging-guided cell transplantation into the brain with radially branched deployment. | Silvestrini MT, Yin D, Martin AJ, Coppes VG, Mann P, Larson PS, Starr PA, Zeng X, Gupta N, Panter SS, Desai TA, Lim DA | Molecular therapy : the journal of the American Society of Gene Therapy | 25138755 | Mol Ther | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25138755 |
Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo. | Ramos AD, Diaz A, Nellore A, Delgado RN, Park KY, Gonzales-Roybal G, Oldham MC, Song JS, Lim DA | Cell stem cell | 23583100 | Cell Stem Cell | 2013 May 2 | https://www.ncbi.nlm.nih.gov/pubmed/23583100 |
Chromatin-based epigenetics of adult subventricular zone neural stem cells. | Gonzales-Roybal G, Lim DA | Frontiers in genetics | 24115953 | Front Genet | 2013 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/24115953 |
Adult neural stem cells stake their ground. | Lim DA, Alvarez-Buylla A | Trends in neurosciences | 25223700 | Trends Neurosci | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25223700 |
The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells. | Ramos AD, Andersen RE, Liu SJ, Nowakowski TJ, Hong SJ, Gertz C, Salinas RD, Zarabi H, Kriegstein AR, Lim DA | Cell stem cell | 25800779 | Cell Stem Cell | 2015 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/25800779 |
An old drug for new ideas: metformin promotes adult neurogenesis and spatial memory formation. | Potts MB, Lim DA | Cell stem cell | 22770236 | Cell Stem Cell | 2012 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/22770236 |
Normalization, bias correction, and peak calling for ChIP-seq. | Diaz A, Park K, Lim DA, Song JS | Statistical applications in genetics and molecular biology | 22499706 | Stat Appl Genet Mol Biol | 2012 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/22499706 |
Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis. | Park DH, Hong SJ, Salinas RD, Liu SJ, Sun SW, Sgualdino J, Testa G, Matzuk MM, Iwamori N, Lim DA | Cell reports | 25176653 | Cell Rep | 2014 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/25176653 |
β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines. | Madden KS, Szpunar MJ, Brown EB | Breast cancer research and treatment | 21234673 | Breast Cancer Res Treat | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21234673 |
In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice. | Bouta EM, Wood RW, Brown EB, Rahimi H, Ritchlin CT, Schwarz EM | The Journal of physiology | 24421350 | J Physiol | 2014 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/24421350 |
Tumor-associated macrophages and stromal TNF-α regulate collagen structure in a breast tumor model as visualized by second harmonic generation. | Burke RM, Madden KS, Perry SW, Zettel ML, Brown EB 3rd | Journal of biomedical optics | 23912760 | J Biomed Opt | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23912760 |
Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells. | Perry SW, Schueckler JM, Burke K, Arcuri GL, Brown EB | BMC cancer | 24010522 | BMC Cancer | 2013 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/24010522 |
Measurement of the ratio of forward-propagating to back-propagating second harmonic signal using a single objective. | Han X, Brown E | Optics express | 20588906 | Opt Express | 2010 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/20588906 |
Measuring intranodal pressure and lymph viscosity to elucidate mechanisms of arthritic flare and therapeutic outcomes. | Bouta EM, Wood RW, Perry SW, Brown EB, Ritchlin CT, Xing L, Schwarz EM | Annals of the New York Academy of Sciences | 22172039 | Ann N Y Acad Sci | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22172039 |
Two-photon and second harmonic microscopy in clinical and translational cancer research. | Perry SW, Burke RM, Brown EB | Annals of biomedical engineering | 22258888 | Ann Biomed Eng | 2012 Feb | https://www.ncbi.nlm.nih.gov/pubmed/22258888 |
The antidepressant desipramine and α2-adrenergic receptor activation promote breast tumor progression in association with altered collagen structure. | Szpunar MJ, Burke KA, Dawes RP, Brown EB, Madden KS | Cancer prevention research (Philadelphia, Pa.) | 24309563 | Cancer Prev Res (Phila) | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24309563 |
In vivo imaging of tumors. | Brown E, Munn LL, Fukumura D, Jain RK | Cold Spring Harbor protocols | 20647356 | Cold Spring Harb Protoc | 2010 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/20647356 |
Fluoxetine modulates breast cancer metastasis to the brain in a murine model. | Shapovalov Y, Zettel M, Spielman SC, Amico-Ruvio SA, Kelly EA, Sipe GO, Dickerson IM, Majewska AK, Brown EB | BMC cancer | 25129445 | BMC Cancer | 2014 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/25129445 |
Second-harmonic generation scattering directionality predicts tumor cell motility in collagen gels. | Burke KA, Dawes RP, Cheema MK, Van Hove A, Benoit DS, Perry SW, Brown E | Journal of biomedical optics | 25625899 | J Biomed Opt | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25625899 |
The role of the lymphatic system in inflammatory-erosive arthritis. | Bouta EM, Li J, Ju Y, Brown EB, Ritchlin CT, Xing L, Schwarz EM | Seminars in cell & developmental biology | 25598390 | Semin Cell Dev Biol | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25598390 |
Chronic Stress Exposure Suppresses Mammary Tumor Growth and Reduces Circulating Exosome TGF-β Content via β-Adrenergic Receptor Signaling in MMTV-PyMT Mice. | Dawes RP, Burke KA, Byun DK, Xu Z, Stastka P, Chan L, Brown EB, Madden KS | Breast cancer : basic and clinical research | 32595275 | Breast Cancer (Auckl) | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32595275 |
Second harmonic generation reveals matrix alterations during breast tumor progression. | Burke K, Tang P, Brown E | Journal of biomedical optics | 23172133 | J Biomed Opt | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23172133 |
Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. | Perry SW, Norman JP, Barbieri J, Brown EB, Gelbard HA | BioTechniques | 21486251 | Biotechniques | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/21486251 |
Engineering superficial zone features in tissue engineered cartilage. | Chen T, Hilton MJ, Brown EB, Zuscik MJ, Awad HA | Biotechnology and bioengineering | 23239161 | Biotechnol Bioeng | 2013 May | https://www.ncbi.nlm.nih.gov/pubmed/23239161 |
Power Doppler ultrasound phenotyping of expanding versus collapsed popliteal lymph nodes in murine inflammatory arthritis. | Bouta EM, Ju Y, Rahimi H, de Mesy-Bentley KL, Wood RW, Xing L, Schwarz EM | PloS one | 24040061 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24040061 |
Early impact of social isolation and breast tumor progression in mice. | Madden KS, Szpunar MJ, Brown EB | Brain, behavior, and immunity | 22610067 | Brain Behav Immun | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/22610067 |
Using second harmonic generation to predict patient outcome in solid tumors. | Burke K, Smid M, Dawes RP, Timmermans MA, Salzman P, van Deurzen CH, Beer DG, Foekens JA, Brown E | BMC cancer | 26603532 | BMC Cancer | 2015 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/26603532 |
Second harmonic generation microscopy reveals altered collagen microstructure in usual interstitial pneumonia versus healthy lung. | Kottmann RM, Sharp J, Owens K, Salzman P, Xiao GQ, Phipps RP, Sime PJ, Brown EB, Perry SW | Respiratory research | 26013144 | Respir Res | 2015 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/26013144 |
Multiphoton fluorescence recovery after photobleaching in bounded systems. | Sullivan KD, Brown EB | Physical review. E, Statistical, nonlinear, and soft matter physics | 21728580 | Phys Rev E Stat Nonlin Soft Matter Phys | 2011 May | https://www.ncbi.nlm.nih.gov/pubmed/21728580 |
Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair. | Huang C, Ness VP, Yang X, Chen H, Luo J, Brown EB, Zhang X | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 25640220 | J Bone Miner Res | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25640220 |
An extracellular MRI polymeric contrast agent that degrades at physiological pH. | Schopf E, Sankaranarayanan J, Chan M, Mattrey R, Almutairi A | Molecular pharmaceutics | 22657107 | Mol Pharm | 2012 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/22657107 |
Inflammation responsive logic gate nanoparticles for the delivery of proteins. | Mahmoud EA, Sankaranarayanan J, Morachis JM, Kim G, Almutairi A | Bioconjugate chemistry | 21688843 | Bioconjug Chem | 2011 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/21688843 |
Light-responsive nanoparticle depot to control release of a small molecule angiogenesis inhibitor in the posterior segment of the eye. | Huu VA, Luo J, Zhu J, Zhu J, Patel S, Boone A, Mahmoud E, McFearin C, Olejniczak J, de Gracia Lux C, Lux J, Fomina N, Huynh M, Zhang K, Almutairi A | Journal of controlled release : official journal of the Controlled Release Society | 25571784 | J Control Release | 2015 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/25571784 |
Gold Nanoparticle-assisted Selective Photothermolysis of Adipose Tissue (NanoLipo). | Sheng W, Alhasan AH, DiBernardo G, Almutairi KM, Rubin JP, DiBernardo BE, Almutairi A | Plastic and reconstructive surgery. Global open | 25587517 | Plast Reconstr Surg Glob Open | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25587517 |
Application of time-resolved fluorescence for direct and continuous probing of release from polymeric delivery vehicles. | Viger ML, Sheng W, McFearin CL, Berezin MY, Almutairi A | Journal of controlled release : official journal of the Controlled Release Society | 23792808 | J Control Release | 2013 Nov 10 | https://www.ncbi.nlm.nih.gov/pubmed/23792808 |
UV and near-IR triggered release from polymeric nanoparticles. | Fomina N, McFearin C, Sermsakdi M, Edigin O, Almutairi A | Journal of the American Chemical Society | 20568765 | J Am Chem Soc | 2010 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/20568765 |
Density gradient multilayer polymerization for creating complex tissue. | Karpiak JV, Ner Y, Almutairi A | Advanced materials (Deerfield Beach, Fla.) | 22318771 | Adv Mater | 2012 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/22318771 |
Increasing materials' response to two-photon NIR light via self-immolative dendritic scaffolds. | Fomina N, McFearin CL, Almutairi A | Chemical communications (Cambridge, England) | 22475792 | Chem Commun (Camb) | 2012 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/22475792 |
Low power, biologically benign NIR light triggers polymer disassembly. | Fomina N, McFearin CL, Sermsakdi M, Morachis JM, Almutairi A | Macromolecules | 22096258 | Macromolecules | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22096258 |
Metal Chelating Crosslinkers Form Nanogels with High Chelation Stability. | Lux J, Chan M, Elst LV, Schopf E, Mahmoud E, Laurent S, Almutairi A | Journal of materials chemistry. B | 24505553 | J Mater Chem B | 2013 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/24505553 |
Exploiting oxidative microenvironments in the body as triggers for drug delivery systems. | Joshi-Barr S, de Gracia Lux C, Mahmoud E, Almutairi A | Antioxidants & redox signaling | 24328819 | Antioxid Redox Signal | 2014 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/24328819 |
Multiresponse strategies to modulate burst degradation and release from nanoparticles. | Sankaranarayanan J, Mahmoud EA, Kim G, Morachis JM, Almutairi A | ACS nano | 20828178 | ACS Nano | 2010 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/20828178 |
Application of fiber-optic attenuated total reflection-FT-IR methods for in situ characterization of protein delivery systems in real time. | McFearin CL, Sankaranarayanan J, Almutairi A | Analytical chemistry | 21476582 | Anal Chem | 2011 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/21476582 |
In vivo time-gated fluorescence imaging with biodegradable luminescent porous silicon nanoparticles. | Gu L, Hall DJ, Qin Z, Anglin E, Joo J, Mooney DJ, Howell SB, Sailor MJ | Nature communications | 23933660 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23933660 |
Biocompatible polymeric nanoparticles degrade and release cargo in response to biologically relevant levels of hydrogen peroxide. | de Gracia Lux C, Joshi-Barr S, Nguyen T, Mahmoud E, Schopf E, Fomina N, Almutairi A | Journal of the American Chemical Society | 22946840 | J Am Chem Soc | 2012 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/22946840 |
Antigen-loaded pH-sensitive hydrogel microparticles are taken up by dendritic cells with no requirement for targeting antibodies. | Ruff LE, Mahmoud EA, Sankaranarayanan J, Morachis JM, Katayama CD, Corr M, Hedrick SM, Almutairi A | Integrative biology : quantitative biosciences from nano to macro | 23060228 | Integr Biol (Camb) | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23060228 |
Nanogels as imaging agents for modalities spanning the electromagnetic spectrum. | Chan M, Almutairi A | Materials horizons | 27398218 | Mater Horiz | 2016 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/27398218 |
Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. | Zhang ZN, Freitas BC, Qian H, Lux J, Acab A, Trujillo CA, Herai RH, Nguyen Huu VA, Wen JH, Joshi-Barr S, Karpiak JV, Engler AJ, Fu XD, Muotri AR, Almutairi A | Proceedings of the National Academy of Sciences of the United States of America | 26944080 | Proc Natl Acad Sci U S A | 2016 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/26944080 |
Iron oxide nanoparticle-based magnetic resonance method to monitor release kinetics from polymeric particles with high resolution. | Chan M, Schopf E, Sankaranarayanan J, Almutairi A | Analytical chemistry | 22891894 | Anal Chem | 2012 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/22891894 |
Tunable protein release from acetalated dextran microparticles: a platform for delivery of protein therapeutics to the heart post-MI. | Suarez S, Grover GN, Braden RL, Christman KL, Almutairi A | Biomacromolecules | 24053580 | Biomacromolecules | 2013 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/24053580 |
Intramolecular Cyclization for Stimuli-Controlled Depolymerization of Polycaprolactone Particles Leading to Disassembly and Payload Release. | de Gracia Lux C, Almutairi A | ACS macro letters | 23814697 | ACS Macro Lett | 2013 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/23814697 |
Physical and chemical strategies for therapeutic delivery by using polymeric nanoparticles. | Morachis JM, Mahmoud EA, Almutairi A | Pharmacological reviews | 22544864 | Pharmacol Rev | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22544864 |
Density gradient multilayered polymerization (DGMP): a novel technique for creating multi-compartment, customizable scaffolds for tissue engineering. | Joshi-Barr S, Karpiak JV, Ner Y, Wen JH, Engler AJ, Almutairi A | Journal of visualized experiments : JoVE | 23426045 | J Vis Exp | 2013 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/23426045 |
Highest Efficiency Two-Photon Degradable Copolymer for Remote Controlled Release. | Olejniczak J, Sankaranarayanan J, Viger ML, Almutairi A | ACS macro letters | 24044102 | ACS Macro Lett | 2013 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/24044102 |
Low power upconverted near-IR light for efficient polymeric nanoparticle degradation and cargo release. | Viger ML, Grossman M, Fomina N, Almutairi A | Advanced materials (Deerfield Beach, Fla.) | 23722298 | Adv Mater | 2013 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/23722298 |
Near-infrared-induced heating of confined water in polymeric particles for efficient payload release. | Viger ML, Sheng W, Doré K, Alhasan AH, Carling CJ, Lux J, de Gracia Lux C, Grossman M, Malinow R, Almutairi A | ACS nano | 24717072 | ACS Nano | 2014 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/24717072 |
A Single UV or Near IR Triggering Event Leads to Polymer Degradation into Small Molecules. | de Gracia Lux C, McFearin CL, Joshi-Barr S, Sankaranarayanan J, Fomina N, Almutairi A | ACS macro letters | 23066523 | ACS Macro Lett | 2012 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/23066523 |
Collective activation of MRI agents via encapsulation and disease-triggered release. | Viger ML, Sankaranarayanan J, de Gracia Lux C, Chan M, Almutairi A | Journal of the American Chemical Society | 23672342 | J Am Chem Soc | 2013 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/23672342 |
Light-triggered chemical amplification to accelerate degradation and release from polymeric particles. | Olejniczak J, Nguyen Huu VA, Lux J, Grossman M, He S, Almutairi A | Chemical communications (Cambridge, England) | 26445896 | Chem Commun (Camb) | 2015 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/26445896 |
Nanogels from metal-chelating crosslinkers as versatile platforms applied to copper-64 PET imaging of tumors and metastases. | Lux J, White AG, Chan M, Anderson CJ, Almutairi A | Theranostics | 25553115 | Theranostics | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25553115 |
In Vivo Visible Light-Triggered Drug Release From an Implanted Depot. | Carling CJ, Viger ML, Huu VA, Garcia AV, Almutairi A | Chemical science | 25598962 | Chem Sci | 2015 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/25598962 |
Photochemical mechanisms of light-triggered release from nanocarriers. | Fomina N, Sankaranarayanan J, Almutairi A | Advanced drug delivery reviews | 22386560 | Adv Drug Deliv Rev | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22386560 |
Intramyocardial injection of hydrogel with high interstitial spread does not impact action potential propagation. | Suarez SL, Rane AA, Muñoz A, Wright AT, Zhang SX, Braden RL, Almutairi A, McCulloch AD, Christman KL | Acta biomaterialia | 26265060 | Acta Biomater | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26265060 |
Long-Lasting and Efficient Tumor Imaging Using a High Relaxivity Polysaccharide Nanogel Magnetic Resonance Imaging Contrast Agent. | Chan M, Lux J, Nishimura T, Akiyoshi K, Almutairi A | Biomacromolecules | 26278775 | Biomacromolecules | 2015 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/26278775 |
Photocontrolled release using one-photon absorption of visible or NIR light. | Olejniczak J, Carling CJ, Almutairi A | Journal of controlled release : official journal of the Controlled Release Society | 26394063 | J Control Release | 2015 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/26394063 |
Adaptation to a new environment allows cooperators to purge cheaters stochastically. | Waite AJ, Shou W | Proceedings of the National Academy of Sciences of the United States of America | 23091010 | Proc Natl Acad Sci U S A | 2012 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/23091010 |
Spatial self-organization favors heterotypic cooperation over cheating. | Momeni B, Waite AJ, Shou W | eLife | 24220506 | Elife | 2013 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/24220506 |
Simulations reveal challenges to artificial community selection and possible strategies for success. | Xie L, Yuan AE, Shou W | PLoS biology | 31237866 | PLoS Biol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31237866 |
Constructing synthetic microbial communities to explore the ecology and evolution of symbiosis. | Waite AJ, Shou W | Methods in molecular biology (Clifton, N.J.) | 24838876 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24838876 |
Using artificial systems to explore the ecology and evolution of symbioses. | Momeni B, Chen CC, Hillesland KL, Waite A, Shou W | Cellular and molecular life sciences : CMLS | 21424911 | Cell Mol Life Sci | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21424911 |
Developing a low-cost milliliter-scale chemostat array for precise control of cellular growth. | Skelding D, Hart SFM, Vidyasagar T, Pozhitkov AE, Shou W | Quantitative biology (Beijing, China) | 31598380 | Quant Biol | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31598380 |
Uncovering and resolving challenges of quantitative modeling in a simplified community of interacting cells. | Hart SFM, Mi H, Green R, Xie L, Pineda JMB, Momeni B, Shou W | PLoS biology | 30794534 | PLoS Biol | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30794534 |
Metabolic excretion associated with nutrient-growth dysregulation promotes the rapid evolution of an overt metabolic defect. | Green R, Sonal, Wang L, Hart SFM, Lu W, Skelding D, Burton JC, Mi H, Capel A, Chen HA, Lin A, Subramaniam AR, Rabinowitz JD, Shou W | PLoS biology | 32833957 | PLoS Biol | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32833957 |
Modeling community population dynamics with the open-source language R. | Green R, Shou W | Methods in molecular biology (Clifton, N.J.) | 24838889 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24838889 |
Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community. | Hart SFM, Pineda JMB, Chen CC, Green R, Shou W | eLife | 31162049 | Elife | 2019 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/31162049 |
High-throughput quantification of microbial birth and death dynamics using fluorescence microscopy. | Hart SFM, Skelding D, Waite AJ, Burton JC, Shou W | Quantitative biology (Beijing, China) | 31598381 | Quant Biol | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31598381 |
Strong inter-population cooperation leads to partner intermixing in microbial communities. | Momeni B, Brileya KA, Fields MW, Shou W | eLife | 23359860 | Elife | 2013 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/23359860 |
Defectors Can Create Conditions That Rescue Cooperation. | Waite AJ, Cannistra C, Shou W | PLoS computational biology | 26690946 | PLoS Comput Biol | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26690946 |
Pleiotropic mutations can rapidly evolve to directly benefit self and cooperative partner despite unfavorable conditions. | Hart SFM, Chen CC, Shou W | eLife | 33501915 | Elife | 2021 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/33501915 |
LINE-1 retrotransposition in the nervous system. | Thomas CA, Paquola AC, Muotri AR | Annual review of cell and developmental biology | 23057747 | Annu Rev Cell Dev Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23057747 |
Modeling anorexia nervosa: transcriptional insights from human iPSC-derived neurons. | Negraes PD, Cugola FR, Herai RH, Trujillo CA, Cristino AS, Chailangkarn T, Muotri AR, Duvvuri V | Translational psychiatry | 28291261 | Transl Psychiatry | 2017 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/28291261 |
Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. | Kim JJ, Savas JN, Miller MT, Hu X, Carromeu C, Lavallée-Adam M, Freitas BCG, Muotri AR, Yates JR 3rd, Ghosh A | PloS one | 30789962 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30789962 |
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. | Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria K, Beltrao-Braga P, Trujillo CA, Mendes APD, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand K, Pierce K, Eichenfield L, Pramparo T, Eyler L, Barnes CC, Courchesne E, Geschwind DH, Gage FH, Wynshaw-Boris A, Muotri AR | Molecular psychiatry | 27378147 | Mol Psychiatry | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27378147 |
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation. | Thomas CA, Tejwani L, Trujillo CA, Negraes PD, Herai RH, Mesci P, Macia A, Crow YJ, Muotri AR | Cell stem cell | 28803918 | Cell Stem Cell | 2017 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/28803918 |
Severe Hypoxia: Consequences to Neural Stem Cells and Neurons. | Felfly H, Zambon AC, Xue J, Muotri A, Zhou D, Snyder EY, Haddad GG | Journal of neurology research | 24348887 | J Neurol Res | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/24348887 |
Evolution, development, and plasticity of the human brain: from molecules to bones. | Hrvoj-Mihic B, Bienvenu T, Stefanacci L, Muotri AR, Semendeferi K | Frontiers in human neuroscience | 24194709 | Front Hum Neurosci | 2013 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/24194709 |
Altered neuronal network and rescue in a human MECP2 duplication model. | Nageshappa S, Carromeu C, Trujillo CA, Mesci P, Espuny-Camacho I, Pasciuto E, Vanderhaeghen P, Verfaillie CM, Raitano S, Kumar A, Carvalho CM, Bagni C, Ramocki MB, Araujo BH, Torres LB, Lupski JR, Van Esch H, Muotri AR | Molecular psychiatry | 26347316 | Mol Psychiatry | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26347316 |
Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome. | Andrade LN, Nathanson JL, Yeo GW, Menck CF, Muotri AR | Human molecular genetics | 22661500 | Hum Mol Genet | 2012 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/22661500 |
Stem cells and modeling of autism spectrum disorders. | Freitas BC, Trujillo CA, Carromeu C, Yusupova M, Herai RH, Muotri AR | Experimental neurology | 23036599 | Exp Neurol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23036599 |
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. | Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR | Molecular psychiatry | 25385366 | Mol Psychiatry | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25385366 |
Micro RNA detection in long-term fixed tissue of cortical glutamatergic pyramidal neurons after targeted laser-capture neuroanatomical microdissection. | Herai RR, Stefanacci L, Hrvoj-Mihic B, Chailangkarn T, Hanson K, Semendeferi K, Muotri AR | Journal of neuroscience methods | 24992573 | J Neurosci Methods | 2014 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/24992573 |
Altered iPSC-derived neurons' sodium channel properties in subjects with Monge's disease. | Zhao HW, Gu XQ, Chailangkarn T, Perkins G, Callacondo D, Appenzeller O, Poulsen O, Zhou D, Muotri AR, Haddad GG | Neuroscience | 25559931 | Neuroscience | 2015 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/25559931 |
The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment. | Acab A, Muotri AR | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics | 25851569 | Neurotherapeutics | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25851569 |
Brains, genes, and primates. | Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, Ringach D, Sejnowski TJ, Silva AC, Strick PL, Wu J, Zhang F | Neuron | 25950631 | Neuron | 2015 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/25950631 |
Modeling neurodevelopmental disorders using human neurons. | Chailangkarn T, Acab A, Muotri AR | Current opinion in neurobiology | 22717528 | Curr Opin Neurobiol | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22717528 |
Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. | Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G | Stem cell research | 23759711 | Stem Cell Res | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23759711 |
Modeling autism spectrum disorders with human neurons. | Beltrão-Braga PC, Muotri AR | Brain research | 26854137 | Brain Res | 2017 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/26854137 |
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids. | Trujillo CA, Adams JW, Negraes PD, Carromeu C, Tejwani L, Acab A, Tsuda B, Thomas CA, Sodhi N, Fichter KM, Romero S, Zanella F, Sejnowski TJ, Ulrich H, Muotri AR | EMBO molecular medicine | 33501759 | EMBO Mol Med | 2021 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/33501759 |
Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment. | Adams JW, Vinokur A, de Souza JS, Austria C, Guerra BS, Herai RH, Wahlin KJ, Muotri AR | Cell reports | 38416640 | Cell Rep | 2024 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/38416640 |
Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. | Cortes CJ, Miranda HC, Frankowski H, Batlevi Y, Young JE, Le A, Ivanov N, Sopher BL, Carromeu C, Muotri AR, Garden GA, La Spada AR | Nature neuroscience | 25108912 | Nat Neurosci | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25108912 |
Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus. | Lovatel GA, Elsner VR, Bertoldi K, Vanzella C, Moysés Fdos S, Vizuete A, Spindler C, Cechinel LR, Netto CA, Muotri AR, Siqueira IR | Neurobiology of learning and memory | 23357282 | Neurobiol Learn Mem | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23357282 |
Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells. | Hrvoj-Mihic B, Marchetto MC, Gage FH, Semendeferi K, Muotri AR | Biological psychiatry | 24041506 | Biol Psychiatry | 2014 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/24041506 |
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. | Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR | Cell | 21074045 | Cell | 2010 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/21074045 |
KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. | Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G | Proceedings of the National Academy of Sciences of the United States of America | 26733678 | Proc Natl Acad Sci U S A | 2016 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/26733678 |
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. | Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, Fredlender C, Randolph-Moore L, Kshirsagar R, Xenitopoulos R, Chou G, Hah N, Muotri AR, Padmanabhan K, Semendeferi K, Gage FH | eLife | 30730291 | Elife | 2019 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/30730291 |
The Human Model: Changing Focus on Autism Research. | Muotri AR | Biological psychiatry | 25861701 | Biol Psychiatry | 2016 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/25861701 |
L1 Retrotransposition in Neural Progenitor Cells. | Muotri AR | Methods in molecular biology (Clifton, N.J.) | 26895053 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26895053 |
Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: a preliminary study. | Elsner VR, Lovatel GA, Moysés F, Bertoldi K, Spindler C, Cechinel LR, Muotri AR, Siqueira IR | Experimental gerontology | 23201423 | Exp Gerontol | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23201423 |
Kinin-B2 receptor activity determines the differentiation fate of neural stem cells. | Trujillo CA, Negraes PD, Schwindt TT, Lameu C, Carromeu C, Muotri AR, Pesquero JB, Cerqueira DM, Pillat MM, de Souza HD, Turaça LT, Abreu JG, Ulrich H | The Journal of biological chemistry | 23132855 | J Biol Chem | 2012 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/23132855 |
Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. | Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH | Proceedings of the National Academy of Sciences of the United States of America | 22159035 | Proc Natl Acad Sci U S A | 2011 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/22159035 |
Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony. | Vessoni AT, Herai RH, Karpiak JV, Leal AM, Trujillo CA, Quinet A, Agnez Lima LF, Menck CF, Muotri AR | Human molecular genetics | 26755826 | Hum Mol Genet | 2016 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/26755826 |
Systematic optimization of human pluripotent stem cells media using Design of Experiments. | Marinho PA, Chailangkarn T, Muotri AR | Scientific reports | 25940691 | Sci Rep | 2015 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/25940691 |
L1 retrotransposition in neurons is modulated by MeCP2. | Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, Gage FH | Nature | 21085180 | Nature | 2010 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/21085180 |
LINE-1: creators of neuronal diversity. | Thomas CA, Muotri AR | Frontiers in bioscience (Elite edition) | 22201983 | Front Biosci (Elite Ed) | 2012 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/22201983 |
A human neurodevelopmental model for Williams syndrome. | Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR | Nature | 27509850 | Nature | 2016 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/27509850 |
Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation. | Pillat MM, Lameu C, Trujillo CA, Glaser T, Cappellari AR, Negraes PD, Battastini AM, Schwindt TT, Muotri AR, Ulrich H | Journal of cell science | 27528403 | J Cell Sci | 2016 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/27528403 |
Characterizing complex structural variation in germline and somatic genomes. | Quinlan AR, Hall IM | Trends in genetics : TIG | 22094265 | Trends Genet | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22094265 |
Defining the DNA uptake specificity of naturally competent Haemophilus influenzae cells. | Mell JC, Hall IM, Redfield RJ | Nucleic acids research | 22753031 | Nucleic Acids Res | 2012 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/22753031 |
YAHA: fast and flexible long-read alignment with optimal breakpoint detection. | Faust GG, Hall IM | Bioinformatics (Oxford, England) | 22829624 | Bioinformatics | 2012 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/22829624 |
Mosaic copy number variation in human neurons. | McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch JR, Hall IM, Gage FH | Science (New York, N.Y.) | 24179226 | Science | 2013 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/24179226 |
Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome. | Quinlan AR, Clark RA, Sokolova S, Leibowitz ML, Zhang Y, Hurles ME, Mell JC, Hall IM | Genome research | 20308636 | Genome Res | 2010 May | https://www.ncbi.nlm.nih.gov/pubmed/20308636 |
Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming. | Quinlan AR, Boland MJ, Leibowitz ML, Shumilina S, Pehrson SM, Baldwin KK, Hall IM | Cell stem cell | 21982236 | Cell Stem Cell | 2011 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/21982236 |
SAMBLASTER: fast duplicate marking and structural variant read extraction. | Faust GG, Hall IM | Bioinformatics (Oxford, England) | 24812344 | Bioinformatics | 2014 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/24812344 |
Identification of Drivers of Aneuploidy in Breast Tumors. | Pfister K, Pipka JL, Chiang C, Liu Y, Clark RA, Keller R, Skoglund P, Guertin MJ, Hall IM, Stukenberg PT | Cell reports | 29847804 | Cell Rep | 2018 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/29847804 |
BEDTools: a flexible suite of utilities for comparing genomic features. | Quinlan AR, Hall IM | Bioinformatics (Oxford, England) | 20110278 | Bioinformatics | 2010 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/20110278 |
LUMPY: a probabilistic framework for structural variant discovery. | Layer RM, Chiang C, Quinlan AR, Hall IM | Genome biology | 24970577 | Genome Biol | 2014 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/24970577 |
Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms. | Malhotra A, Lindberg M, Faust GG, Leibowitz ML, Clark RA, Layer RM, Quinlan AR, Hall IM | Genome research | 23410887 | Genome Res | 2013 May | https://www.ncbi.nlm.nih.gov/pubmed/23410887 |
Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations. | Malhotra A, Wang Y, Waters J, Chen K, Meric-Bernstam F, Hall IM, Navin NE | Genome medicine | 25729435 | Genome Med | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25729435 |
SpeedSeq: ultra-fast personal genome analysis and interpretation. | Chiang C, Layer RM, Faust GG, Lindberg MR, Rose DB, Garrison EP, Marth GT, Quinlan AR, Hall IM | Nature methods | 26258291 | Nat Methods | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26258291 |
The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning. | Hazen JL, Faust GG, Rodriguez AR, Ferguson WC, Shumilina S, Clark RA, Boland MJ, Martin G, Chubukov P, Tsunemoto RK, Torkamani A, Kupriyanov S, Hall IM, Baldwin KK | Neuron | 26948891 | Neuron | 2016 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/26948891 |
Noninvasive determination of 2-[18F]-fluoroisonicotinic acid hydrazide pharmacokinetics by positron emission tomography in Mycobacterium tuberculosis-infected mice. | Weinstein EA, Liu L, Ordonez AA, Wang H, Hooker JM, Tonge PJ, Jain SK | Antimicrobial agents and chemotherapy | 23006755 | Antimicrob Agents Chemother | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23006755 |
Role of Mycobacterium tuberculosis pknD in the pathogenesis of central nervous system tuberculosis. | Be NA, Bishai WR, Jain SK | BMC microbiology | 22243650 | BMC Microbiol | 2012 Jan 13 | https://www.ncbi.nlm.nih.gov/pubmed/22243650 |
Template Registration with Missing Parts: Application to the Segmentation of M. Tuberculosis Infected Lungs. | Vidal C, Hewitt J, Davis S, Younes L, Jain S, Jedynak B | Proceedings. IEEE International Symposium on Biomedical Imaging | 26146531 | Proc IEEE Int Symp Biomed Imaging | 2009 Jun-Jul | https://www.ncbi.nlm.nih.gov/pubmed/26146531 |
Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation. | Kübler A, Luna B, Larsson C, Ammerman NC, Andrade BB, Orandle M, Bock KW, Xu Z, Bagci U, Mollura DJ, Marshall J, Burns J, Winglee K, Ahidjo BA, Cheung LS, Klunk M, Jain SK, Kumar NP, Babu S, Sher A, Friedland JS, Elkington PT, Bishai WR | The Journal of pathology | 25186281 | J Pathol | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25186281 |
Efficient ribcage segmentation from CT scans using shape features. | Xu Z, Bagci U, Jonsson C, Jain S, Mollura DJ | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 25570597 | Annu Int Conf IEEE Eng Med Biol Soc | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25570597 |
Accurate and efficient separation of left and right lungs from 3D CT scans: A generic hysteresis approach. | Ziyue Xu, Bagci U, Jonsson C, Jain S, Mollura DJ | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 25571373 | Annu Int Conf IEEE Eng Med Biol Soc | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25571373 |
Microglia activation in a pediatric rabbit model of tuberculous meningitis. | Tucker EW, Pokkali S, Zhang Z, DeMarco VP, Klunk M, Smith ES, Ordonez AA, Penet MF, Bhujwalla Z, Jain SK, Kannan S | Disease models & mechanisms | 27935825 | Dis Model Mech | 2016 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/27935825 |
Modifiable risk factors associated with tuberculosis disease in children in Pune, India. | Jubulis J, Kinikar A, Ithape M, Khandave M, Dixit S, Hotalkar S, Kulkarni V, Mave V, Gupte N, Kagal A, Jain S, Bharadwaj R, Gupta A | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | 24429313 | Int J Tuberc Lung Dis | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24429313 |
Novel vaccine strategies against tuberculosis: a road less travelled. | Pokkali S, Jain S | Expert review of vaccines | 24195477 | Expert Rev Vaccines | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24195477 |
Pediatric tuberculosis in young children in India: a prospective study. | Jain SK, Ordonez A, Kinikar A, Gupte N, Thakar M, Mave V, Jubulis J, Dharmshale S, Desai S, Hatolkar S, Kagal A, Lalvani A, Gupta A, Bharadwaj R | BioMed research international | 24386640 | Biomed Res Int | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24386640 |
Imaging Chronic Tuberculous Lesions Using Sodium [(18)F]Fluoride Positron Emission Tomography in Mice. | Ordonez AA, DeMarco VP, Klunk MH, Pokkali S, Jain SK | Molecular imaging and biology | 25750032 | Mol Imaging Biol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25750032 |
Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology. | Ordonez AA, Pokkali S, Sanchez-Bautista J, Klunk MH, Urbanowski ME, Kübler A, Bishai WR, Elkington PT, Jain SK | The Journal of infectious diseases | 29920600 | J Infect Dis | 2019 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/29920600 |
Incorporating User Input in Template-Based Segmentation. | Vidal C, Beggs D, Younes L, Jain SK, Jedynak B | Proceedings. IEEE International Symposium on Biomedical Imaging | 26146532 | Proc IEEE Int Symp Biomed Imaging | 2011 Mar-Apr | https://www.ncbi.nlm.nih.gov/pubmed/26146532 |
White paper report of the 2011 RAD-AID Conference on International Radiology for Developing Countries: integrating multidisciplinary strategies for imaging services in the developing world. | Everton KL, Mazal J, Mollura DJ, RAD-AID Conference Writing Group | Journal of the American College of Radiology : JACR | 22748790 | J Am Coll Radiol | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22748790 |
Strain-dependent CNS dissemination in guinea pigs after Mycobacterium tuberculosis aerosol challenge. | Be NA, Klinkenberg LG, Bishai WR, Karakousis PC, Jain SK | Tuberculosis (Edinburgh, Scotland) | 21831713 | Tuberculosis (Edinb) | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21831713 |
Imaging Enterobacteriaceae infection in vivo with 18F-fluorodeoxysorbitol positron emission tomography. | Weinstein EA, Ordonez AA, DeMarco VP, Murawski AM, Pokkali S, MacDonald EM, Klunk M, Mease RC, Pomper MG, Jain SK | Science translational medicine | 25338757 | Sci Transl Med | 2014 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/25338757 |
Segmentation of PET images for computer-aided functional quantification of tuberculosis in small animal models. | Foster B, Bagci U, Ziyue Xu, Dey B, Luna B, Bishai W, Jain S, Mollura DJ | IEEE transactions on bio-medical engineering | 24235292 | IEEE Trans Biomed Eng | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24235292 |
Extensively drug-resistant tuberculosis in a young child after travel to India. | Salazar-Austin N, Ordonez AA, Hsu AJ, Benson JE, Mahesh M, Menachery E, Razeq JH, Salfinger M, Starke JR, Milstone AM, Parrish N, Nuermberger EL, Jain SK | The Lancet. Infectious diseases | 26607130 | Lancet Infect Dis | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26607130 |
The biodistribution of 5-[18F]fluoropyrazinamide in Mycobacterium tuberculosis-infected mice determined by positron emission tomography. | Zhang Z, Ordonez AA, Smith-Jones P, Wang H, Gogarty KR, Daryaee F, Bambarger LE, Chang YS, Jain SK, Tonge PJ | PloS one | 28151985 | PLoS One | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28151985 |
In vivo prediction of tuberculosis-associated cavity formation in rabbits. | Luna B, Kubler A, Larsson C, Foster B, Bagci U, Mollura DJ, Jain SK, Bishai WR | The Journal of infectious diseases | 25117755 | J Infect Dis | 2015 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/25117755 |
Noninvasive molecular imaging of tuberculosis-associated inflammation with radioiodinated DPA-713. | Foss CA, Harper JS, Wang H, Pomper MG, Jain SK | The Journal of infectious diseases | 23901092 | J Infect Dis | 2013 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/23901092 |
Novel interferon-gamma assays for diagnosing tuberculosis in young children in India. | Shaikh N, Gupte A, Dharmshale S, Pokkali S, Thakar M, Upadhye VJ, Ordonez AA, Kinikar A, Gupte N, Mave V, Kagal A, Gupta A, Lalvani A, Paranjpe R, Bharadwaj R, Jain SK | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | 28284256 | Int J Tuberc Lung Dis | 2017 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/28284256 |
The Promise of Molecular Imaging in the Study and Treatment of Infectious Diseases. | Jain SK | Molecular imaging and biology | 28155078 | Mol Imaging Biol | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28155078 |
Nuclear imaging: a powerful novel approach for tuberculosis. | Johnson DH, Via LE, Kim P, Laddy D, Lau CY, Weinstein EA, Jain S | Nuclear medicine and biology | 25195017 | Nucl Med Biol | 2014 Nov-Dec | https://www.ncbi.nlm.nih.gov/pubmed/25195017 |
Determination of [11C]rifampin pharmacokinetics within Mycobacterium tuberculosis-infected mice by using dynamic positron emission tomography bioimaging. | DeMarco VP, Ordonez AA, Klunk M, Prideaux B, Wang H, Zhuo Z, Tonge PJ, Dannals RF, Holt DP, Lee CK, Weinstein EA, Dartois V, Dooley KE, Jain SK | Antimicrobial agents and chemotherapy | 26169396 | Antimicrob Agents Chemother | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26169396 |
A Systematic Approach for Developing Bacteria-Specific Imaging Tracers. | Ordonez AA, Weinstein EA, Bambarger LE, Saini V, Chang YS, DeMarco VP, Klunk MH, Urbanowski ME, Moulton KL, Murawski AM, Pokkali S, Kalinda AS, Jain SK | Journal of nuclear medicine : official publication, Society of Nuclear Medicine | 27635025 | J Nucl Med | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27635025 |
Vaccination with recombinant Mycobacterium tuberculosis PknD attenuates bacterial dissemination to the brain in guinea pigs. | Skerry C, Pokkali S, Pinn M, Be NA, Harper J, Karakousis PC, Jain SK | PloS one | 23776655 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23776655 |
A computational pipeline for quantification of pulmonary infections in small animal models using serial PET-CT imaging. | Bagci U, Foster B, Miller-Jaster K, Luna B, Dey B, Bishai WR, Jonsson CB, Jain S, Mollura DJ | EJNMMI research | 23879987 | EJNMMI Res | 2013 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/23879987 |
Novel adjunctive therapies for the treatment of tuberculosis. | Ordonez AA, Maiga M, Gupta S, Weinstein EA, Bishai WR, Jain SK | Current molecular medicine | 24236454 | Curr Mol Med | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24236454 |
Imaging the evolution of reactivation pulmonary tuberculosis in mice using 18F-FDG PET. | Murawski AM, Gurbani S, Harper JS, Klunk M, Younes L, Jain SK, Jedynak BM | Journal of nuclear medicine : official publication, Society of Nuclear Medicine | 25082854 | J Nucl Med | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25082854 |
Characterization of a novel necrotic granuloma model of latent tuberculosis infection and reactivation in mice. | Dutta NK, Illei PB, Jain SK, Karakousis PC | The American journal of pathology | 24815353 | Am J Pathol | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24815353 |
Pathogenesis of central nervous system tuberculosis. | Be NA, Kim KS, Bishai WR, Jain SK | Current molecular medicine | 19275620 | Curr Mol Med | 2009 Mar | https://www.ncbi.nlm.nih.gov/pubmed/19275620 |
Adjunctive TNF inhibition with standard treatment enhances bacterial clearance in a murine model of necrotic TB granulomas. | Skerry C, Harper J, Klunk M, Bishai WR, Jain SK | PloS one | 22761866 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22761866 |
Computer-aided detection and quantification of cavitary tuberculosis from CT scans. | Xu Z, Bagci U, Kubler A, Luna B, Jain S, Bishai WR, Mollura DJ | Medical physics | 24320475 | Med Phys | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24320475 |
Oral-Only Linezolid-Rifampin Is Highly Effective Compared with Other Antibiotics for Periprosthetic Joint Infection: Study of a Mouse Model. | Thompson JM, Saini V, Ashbaugh AG, Miller RJ, Ordonez AA, Ortines RV, Wang Y, Sterling RS, Jain SK, Miller LS | The Journal of bone and joint surgery. American volume | 28419033 | J Bone Joint Surg Am | 2017 Apr 19 | https://www.ncbi.nlm.nih.gov/pubmed/28419033 |
Positron Emission Tomography Imaging with 2-[(18)F]F- p-Aminobenzoic Acid Detects Staphylococcus aureus Infections and Monitors Drug Response. | Zhang Z, Ordonez AA, Wang H, Li Y, Gogarty KR, Weinstein EA, Daryaee F, Merino J, Yoon GE, Kalinda AS, Mease RC, Iuliano JN, Smith-Jones PM, Jain SK, Tonge PJ | ACS infectious diseases | 30067329 | ACS Infect Dis | 2018 Nov 9 | https://www.ncbi.nlm.nih.gov/pubmed/30067329 |
Radioiodinated DPA-713 imaging correlates with bactericidal activity of tuberculosis treatments in mice. | Ordonez AA, Pokkali S, DeMarco VP, Klunk M, Mease RC, Foss CA, Pomper MG, Jain SK | Antimicrobial agents and chemotherapy | 25403669 | Antimicrob Agents Chemother | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25403669 |
Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions. | Harper J, Skerry C, Davis SL, Tasneen R, Weir M, Kramnik I, Bishai WR, Pomper MG, Nuermberger EL, Jain SK | The Journal of infectious diseases | 22198962 | J Infect Dis | 2012 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/22198962 |
Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9. | Ordonez AA, Tasneen R, Pokkali S, Xu Z, Converse PJ, Klunk MH, Mollura DJ, Nuermberger EL, Jain SK | Disease models & mechanisms | 27482816 | Dis Model Mech | 2016 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/27482816 |
Regulatory interactions maintaining self-renewal of human embryonic stem cells as revealed through a systems analysis of PI3K/AKT pathway. | Mathew S, Sundararaj S, Mamiya H, Banerjee I | Bioinformatics (Oxford, England) | 24778109 | Bioinformatics | 2014 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/24778109 |
Global sensitivity analysis of a mathematical model of acute inflammation identifies nonlinear dependence of cumulative tissue damage on host interleukin-6 responses. | Mathew S, Bartels J, Banerjee I, Vodovotz Y | Journal of theoretical biology | 24909493 | J Theor Biol | 2014 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/24909493 |
Inducing endoderm differentiation by modulating mechanical properties of soft substrates. | Jaramillo M, Singh SS, Velankar S, Kumta PN, Banerjee I | Journal of tissue engineering and regenerative medicine | 23008262 | J Tissue Eng Regen Med | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23008262 |
Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering. | Goh SK, Bertera S, Olsen P, Candiello JE, Halfter W, Uechi G, Balasubramani M, Johnson SA, Sicari BM, Kollar E, Badylak SF, Banerjee I | Biomaterials | 23787110 | Biomaterials | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23787110 |
Quantitative Analysis of Robustness of Dynamic Response and Signal Transfer in Insulin mediated PI3K/AKT Pathway. | Mathew S, Banerjee I | Computers & chemical engineering | 25506104 | Comput Chem Eng | 2014 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/25506104 |
Cse1l is a negative regulator of CFTR-dependent fluid secretion. | Bagnat M, Navis A, Herbstreith S, Brand-Arzamendi K, Curado S, Gabriel S, Mostov K, Huisken J, Stainier DY | Current biology : CB | 20933420 | Curr Biol | 2010 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/20933420 |
The vacuole within: how cellular organization dictates notochord function. | Ellis K, Hoffman BD, Bagnat M | Bioarchitecture | 23887209 | Bioarchitecture | 2013 May-Jun | https://www.ncbi.nlm.nih.gov/pubmed/23887209 |
Distinct roles for luminal acidification in apical protein sorting and trafficking in zebrafish. | Levic DS, Ryan S, Marjoram L, Honeycutt J, Bagwell J, Bagnat M | The Journal of cell biology | 32328632 | J Cell Biol | 2020 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/32328632 |
Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling. | Alvers AL, Ryan S, Scherz PJ, Huisken J, Bagnat M | Development (Cambridge, England) | 24504339 | Development | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24504339 |
Cftr controls lumen expansion and function of Kupffer's vesicle in zebrafish. | Navis A, Marjoram L, Bagnat M | Development (Cambridge, England) | 23487313 | Development | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23487313 |
Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract. | Kanther M, Sun X, Mühlbauer M, Mackey LC, Flynn EJ 3rd, Bagnat M, Jobin C, Rawls JF | Gastroenterology | 21439961 | Gastroenterology | 2011 Jul | https://www.ncbi.nlm.nih.gov/pubmed/21439961 |
Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish. | Ryan S, Willer J, Marjoram L, Bagwell J, Mankiewicz J, Leshchiner I, Goessling W, Bagnat M, Katsanis N | Development (Cambridge, England) | 24130329 | Development | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24130329 |
Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis. | Ellis K, Bagwell J, Bagnat M | The Journal of cell biology | 23460678 | J Cell Biol | 2013 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/23460678 |
Loss of cftr function leads to pancreatic destruction in larval zebrafish. | Navis A, Bagnat M | Developmental biology | 25592226 | Dev Biol | 2015 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/25592226 |
Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs. | Rodríguez-Fraticelli AE, Bagwell J, Bosch-Fortea M, Boncompain G, Reglero-Real N, García-León MJ, Andrés G, Toribio ML, Alonso MA, Millán J, Perez F, Bagnat M, Martín-Belmonte F | Nature cell biology | 25706235 | Nat Cell Biol | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25706235 |
SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells. | Shimozaki K, Zhang CL, Suh H, Denli AM, Evans RM, Gage FH | The Journal of biological chemistry | 22194602 | J Biol Chem | 2012 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/22194602 |
Engineering new neurons: in vivo reprogramming in mammalian brain and spinal cord. | Wang LL, Zhang CL | Cell and tissue research | 29170823 | Cell Tissue Res | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29170823 |
TLX: A master regulator for neural stem cell maintenance and neurogenesis. | Islam MM, Zhang CL | Biochimica et biophysica acta | 24930777 | Biochim Biophys Acta | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24930777 |
Orphan nuclear receptor TLX regulates astrogenesis by modulating BMP signaling. | Qin S, Niu W, Iqbal N, Smith DK, Zhang CL | Frontiers in neuroscience | 24782704 | Front Neurosci | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24782704 |
In vivo reprogramming of astrocytes to neuroblasts in the adult brain. | Niu W, Zang T, Zou Y, Fang S, Smith DK, Bachoo R, Zhang CL | Nature cell biology | 24056302 | Nat Cell Biol | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24056302 |
The p53 Pathway Controls SOX2-Mediated Reprogramming in the Adult Mouse Spinal Cord. | Wang LL, Su Z, Tai W, Zou Y, Xu XM, Zhang CL | Cell reports | 27732862 | Cell Rep | 2016 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/27732862 |
Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron Reprogramming. | Smith DK, Yang J, Liu ML, Zhang CL | Stem cell reports | 28157484 | Stem Cell Reports | 2016 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/28157484 |
MicroRNA-146a inhibits glioma development by targeting Notch1. | Mei J, Bachoo R, Zhang CL | Molecular and cellular biology | 21730286 | Mol Cell Biol | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21730286 |
Activation of postnatal neural stem cells requires nuclear receptor TLX. | Niu W, Zou Y, Shen C, Zhang CL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 21957244 | J Neurosci | 2011 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/21957244 |
The nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche. | Zou Y, Niu W, Qin S, Downes M, Burns DK, Zhang CL | Molecular and cellular biology | 23028043 | Mol Cell Biol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23028043 |
Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons. | Liu ML, Zang T, Zou Y, Chang JC, Gibson JR, Huber KM, Zhang CL | Nature communications | 23873306 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23873306 |
Cross-talk between KLF4 and STAT3 regulates axon regeneration. | Qin S, Zou Y, Zhang CL | Nature communications | 24129709 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24129709 |
In vivo conversion of astrocytes to neurons in the injured adult spinal cord. | Su Z, Niu W, Liu ML, Zou Y, Zhang CL | Nature communications | 24569435 | Nat Commun | 2014 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/24569435 |
Role of Kruppel-like factor 4 in neurogenesis and radial neuronal migration in the developing cerebral cortex. | Qin S, Zhang CL | Molecular and cellular biology | 22907754 | Mol Cell Biol | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/22907754 |
Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice. | Qin S, Liu M, Niu W, Zhang CL | Proceedings of the National Academy of Sciences of the United States of America | 22160720 | Proc Natl Acad Sci U S A | 2011 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/22160720 |
Enhancer Analysis Unveils Genetic Interactions between TLX and SOX2 in Neural Stem Cells and In Vivo Reprogramming. | Islam MM, Smith DK, Niu W, Fang S, Iqbal N, Sun G, Shi Y, Zhang CL | Stem cell reports | 26607952 | Stem Cell Reports | 2015 Nov 10 | https://www.ncbi.nlm.nih.gov/pubmed/26607952 |
Transcription-Factor-Dependent Control of Adult Hippocampal Neurogenesis. | Beckervordersandforth R, Zhang CL, Lie DC | Cold Spring Harbor perspectives in biology | 26430216 | Cold Spring Harb Perspect Biol | 2015 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/26430216 |
Direct Reprogramming Rather than iPSC-Based Reprogramming Maintains Aging Hallmarks in Human Motor Neurons. | Tang Y, Liu ML, Zang T, Zhang CL | Frontiers in molecular neuroscience | 29163034 | Front Mol Neurosci | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29163034 |
Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain. | Niu W, Zang T, Wang LL, Zou Y, Zhang CL | Stem cell reports | 30318292 | Stem Cell Reports | 2018 Nov 13 | https://www.ncbi.nlm.nih.gov/pubmed/30318292 |
Systemic redox regulation of cellular information processing. | Dwivedi G, Kemp ML | Antioxidants & redox signaling | 21939387 | Antioxid Redox Signal | 2012 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/21939387 |
A switching mechanism in doxorubicin bioactivation can be exploited to control doxorubicin toxicity. | Finn NA, Findley HW, Kemp ML | PLoS computational biology | 21935349 | PLoS Comput Biol | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21935349 |
A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses. | Adimora NJ, Jones DP, Kemp ML | Antioxidants & redox signaling | 20121341 | Antioxid Redox Signal | 2010 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/20121341 |
Calcium Dynamics of Ex Vivo Long-Term Cultured CD8+ T Cells Are Regulated by Changes in Redox Metabolism. | Rivet CA, Kniss-James AS, Gran MA, Potnis A, Hill A, Lu H, Kemp ML | PloS one | 27526200 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27526200 |
Spatially-resolved intracellular sensing of hydrogen peroxide in living cells. | Warren EA, Netterfield TS, Sarkar S, Kemp ML, Payne CK | Scientific reports | 26585385 | Sci Rep | 2015 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/26585385 |
Pro-oxidant and antioxidant effects of N-acetylcysteine regulate doxorubicin-induced NF-kappa B activity in leukemic cells. | Finn NA, Kemp ML | Molecular bioSystems | 22134636 | Mol Biosyst | 2012 Feb | https://www.ncbi.nlm.nih.gov/pubmed/22134636 |
Kinetic Modeling of ABCG2 Transporter Heterogeneity: A Quantitative, Single-Cell Analysis of the Side Population Assay. | Prasanphanich AF, White DE, Gran MA, Kemp ML | PLoS computational biology | 27851764 | PLoS Comput Biol | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27851764 |
TiO(2) Nanoparticle-Induced Oxidation of the Plasma Membrane: Importance of the Protein Corona. | Runa S, Lakadamyali M, Kemp ML, Payne CK | The journal of physical chemistry. B | 28844138 | J Phys Chem B | 2017 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/28844138 |
Quantification of degeneracy in biological systems for characterization of functional interactions between modules. | Li Y, Dwivedi G, Huang W, Kemp ML, Yi Y | Journal of theoretical biology | 22619750 | J Theor Biol | 2012 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/22619750 |
Single cell transcriptional analysis reveals novel innate immune cell types. | Kippner LE, Kim J, Gibson G, Kemp ML | PeerJ | 25024920 | PeerJ | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25024920 |
Redox processes inform multivariate transdifferentiation trajectories associated with TGFβ-induced epithelial-mesenchymal transition. | Prasanphanich AF, Arencibia CA, Kemp ML | Free radical biology & medicine | 25088330 | Free Radic Biol Med | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25088330 |
Dynamic Redox Regulation of IL-4 Signaling. | Dwivedi G, Gran MA, Bagchi P, Kemp ML | PLoS computational biology | 26562652 | PLoS Comput Biol | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26562652 |
Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenase. | Kippner LE, Finn NA, Shukla S, Kemp ML | BMC systems biology | 21995976 | BMC Syst Biol | 2011 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/21995976 |
Network reconstruction reveals new links between aging and calorie restriction in yeast. | Balázsi G | HFSP journal | 21119761 | HFSP J | 2010 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21119761 |
Cellular decision making and biological noise: from microbes to mammals. | Balázsi G, van Oudenaarden A, Collins JJ | Cell | 21414483 | Cell | 2011 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/21414483 |
A common repressor pool results in indeterminacy of extrinsic noise. | Stamatakis M, Adams RM, Balázsi G | Chaos (Woodbury, N.Y.) | 22225397 | Chaos | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22225397 |
Network inference and network response identification: moving genome-scale data to the next level of biological discovery. | Veiga DF, Dutta B, Balázsi G | Molecular bioSystems | 20174676 | Mol Biosyst | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20174676 |
Tuning and controlling gene expression noise in synthetic gene networks. | Murphy KF, Adams RM, Wang X, Balázsi G, Collins JJ | Nucleic acids research | 20211838 | Nucleic Acids Res | 2010 May | https://www.ncbi.nlm.nih.gov/pubmed/20211838 |
Coherent feedforward transcriptional regulatory motifs enhance drug resistance. | Charlebois DA, Balázsi G, Kærn M | Physical review. E, Statistical, nonlinear, and soft matter physics | 25353830 | Phys Rev E Stat Nonlin Soft Matter Phys | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/25353830 |
Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions. | Lee J, Lee J, Farquhar KS, Yun J, Frankenberger CA, Bevilacqua E, Yeung K, Kim EJ, Balázsi G, Rosner MR | Proceedings of the National Academy of Sciences of the United States of America | 24395801 | Proc Natl Acad Sci U S A | 2014 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/24395801 |
Transferring a synthetic gene circuit from yeast to mammalian cells. | Nevozhay D, Zal T, Balázsi G | Nature communications | 23385595 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23385595 |
Efflux Pump Control Alters Synthetic Gene Circuit Function. | Diao J, Charlebois DA, Nevozhay D, Bódi Z, Pál C, Balázsi G | ACS synthetic biology | 27111147 | ACS Synth Biol | 2016 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/27111147 |
Role of network-mediated stochasticity in mammalian drug resistance. | Farquhar KS, Charlebois DA, Szenk M, Cohen J, Nevozhay D, Balázsi G | Nature communications | 31235692 | Nat Commun | 2019 Jun 24 | https://www.ncbi.nlm.nih.gov/pubmed/31235692 |
Adaptive evolution of the lactose utilization network in experimentally evolved populations of Escherichia coli. | Quan S, Ray JC, Kwota Z, Duong T, Balázsi G, Cooper TF, Monds RD | PLoS genetics | 22253602 | PLoS Genet | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22253602 |
Mapping the environmental fitness landscape of a synthetic gene circuit. | Nevozhay D, Adams RM, Van Itallie E, Bennett MR, Balázsi G | PLoS computational biology | 22511863 | PLoS Comput Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22511863 |
Stress-response balance drives the evolution of a network module and its host genome. | González C, Ray JC, Manhart M, Adams RM, Nevozhay D, Morozov AV, Balázsi G | Molecular systems biology | 26324468 | Mol Syst Biol | 2015 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/26324468 |
The interplay of multiple feedback loops with post-translational kinetics results in bistability of mycobacterial stress response. | Tiwari A, Balázsi G, Gennaro ML, Igoshin OA | Physical biology | 20733247 | Phys Biol | 2010 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/20733247 |
Negative Regulation Gene Circuits for Efflux Pump Control. | Charlebois DA, Diao J, Nevozhay D, Balázsi G | Methods in molecular biology (Clifton, N.J.) | 29754221 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29754221 |
Cellular Growth Arrest and Persistence from Enzyme Saturation. | Ray JC, Wickersheim ML, Jalihal AP, Adeshina YO, Cooper TF, Balázsi G | PLoS computational biology | 27010473 | PLoS Comput Biol | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/27010473 |
Disadvantages and benefits of evolved unicellularity versus multicellularity in budding yeast. | Kuzdzal-Fick JJ, Chen L, Balázsi G | Ecology and evolution | 31410258 | Ecol Evol | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31410258 |
Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection. | Rohde KH, Veiga DF, Caldwell S, Balázsi G, Russell DG | PLoS pathogens | 22737072 | PLoS Pathog | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22737072 |
Two-dimensionality of yeast colony expansion accompanied by pattern formation. | Chen L, Noorbakhsh J, Adams RM, Samaniego-Evans J, Agollah G, Nevozhay D, Kuzdzal-Fick J, Mehta P, Balázsi G | PLoS computational biology | 25504059 | PLoS Comput Biol | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25504059 |
Phenotypic heterogeneity promotes adaptive evolution. | Bódi Z, Farkas Z, Nevozhay D, Kalapis D, Lázár V, Csörgő B, Nyerges Á, Szamecz B, Fekete G, Papp B, Araújo H, Oliveira JL, Moura G, Santos MAS, Székely T Jr, Balázsi G, Pál C | PLoS biology | 28486496 | PLoS Biol | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28486496 |
Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo. | Chenaux G, Matt L, Hill TC, Kaur I, Liu XB, Kirk LM, Speca DJ, McMahon SA, Zito K, Hell JW, Díaz E | eNeuro | 27800545 | eNeuro | 2016 Sep-Oct | https://www.ncbi.nlm.nih.gov/pubmed/27800545 |
Role of MXD3 in proliferation of DAOY human medulloblastoma cells. | Barisone GA, Ngo T, Tran M, Cortes D, Shahi MH, Nguyen TV, Perez-Lanza D, Matayasuwan W, Díaz E | PloS one | 22808009 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22808009 |
Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia. | Satake N, Duong C, Chen C, Barisone GA, Diaz E, Tuscano J, Rocke DM, Nolta J, Nitin N | British journal of haematology | 25196579 | Br J Haematol | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25196579 |
Alternative Splicing of MXD3 and Its Regulation of MXD3 Levels in Glioblastoma. | Ngo T, Corrales A, Bourne T, Elmojahid S, Lam KS, Díaz E | Frontiers in molecular biosciences | 30838212 | Front Mol Biosci | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30838212 |
Mechanisms of excitatory synapse maturation by trans-synaptic organizing complexes. | McMahon SA, Díaz E | Current opinion in neurobiology | 21242087 | Curr Opin Neurobiol | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21242087 |
SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function. | Matt L, Kirk LM, Chenaux G, Speca DJ, Puhger KR, Pride MC, Qneibi M, Haham T, Plambeck KE, Stern-Bach Y, Silverman JL, Crawley JN, Hell JW, Díaz E | Cell reports | 29490264 | Cell Rep | 2018 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/29490264 |
Distribution of the SynDIG4/proline-rich transmembrane protein 1 in rat brain. | Kirk LM, Ti SW, Bishop HI, Orozco-Llamas M, Pham M, Trimmer JS, Díaz E | The Journal of comparative neurology | 26660156 | J Comp Neurol | 2016 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/26660156 |
Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells. | Barisone GA, Satake N, Lewis C, Duong C, Chen C, Lam KS, Nolta J, Dίaz E | Blood cells, molecules & diseases | 25554682 | Blood Cells Mol Dis | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25554682 |
Focus formation: a cell-based assay to determine the oncogenic potential of a gene. | Alvarez A, Barisone GA, Diaz E | Journal of visualized experiments : JoVE | 25590282 | J Vis Exp | 2014 Dec 31 | https://www.ncbi.nlm.nih.gov/pubmed/25590282 |
DNA microarrays: sample quality control, array hybridization and scanning. | Diaz E, Barisone GA | Journal of visualized experiments : JoVE | 21445042 | J Vis Exp | 2011 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/21445042 |
MXD3 regulation of DAOY cell proliferation dictated by time course of activation. | Ngo T, Barisone GA, Lam KS, Dίaz E | BMC cell biology | 25053245 | BMC Cell Biol | 2014 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/25053245 |
Activity-Dependent Palmitoylation Controls SynDIG1 Stability, Localization, and Function. | Kaur I, Yarov-Yarovoy V, Kirk LM, Plambeck KE, Barragan EV, Ontiveros ES, Díaz E | The Journal of neuroscience : the official journal of the Society for Neuroscience | 27445135 | J Neurosci | 2016 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/27445135 |
Whole exome sequencing reveals a functional mutation in the GAIN domain of the Bai2 receptor underlying a forward mutagenesis hyperactivity QTL. | Speca DJ, Trimmer JS, Peterson AS, Díaz E | Mammalian genome : official journal of the International Mammalian Genome Society | 28894906 | Mamm Genome | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/28894906 |
Designing artificial enzymes by intuition and computation. | Nanda V, Koder RL | Nature chemistry | 21124375 | Nat Chem | 2010 Jan | https://www.ncbi.nlm.nih.gov/pubmed/21124375 |
Metal Stabilization of Collagen and de Novo Designed Mimetic Peptides. | Parmar AS, Xu F, Pike DH, Belure SV, Hasan NF, Drzewiecki KE, Shreiber DI, Nanda V | Biochemistry | 26225466 | Biochemistry | 2015 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/26225466 |
Circular Dichroism Spectroscopy of Collagen Fibrillogenesis: A New Use for an Old Technique. | Drzewiecki KE, Grisham DR, Parmar AS, Nanda V, Shreiber DI | Biophysical journal | 27926839 | Biophys J | 2016 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/27926839 |
Structural principles for computational and de novo design of 4Fe-4S metalloproteins. | Nanda V, Senn S, Pike DH, Rodriguez-Granillo A, Hansen WA, Khare SD, Noy D | Biochimica et biophysica acta | 26449207 | Biochim Biophys Acta | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26449207 |
Collagen mimetic peptide discs promote assembly of a broad range of natural protein fibers through hydrophobic interactions. | McGuinness K, Nanda V | Organic & biomolecular chemistry | 28678287 | Org Biomol Chem | 2017 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/28678287 |
Control of Collagen Stability and Heterotrimer Specificity through Repulsive Electrostatic Interactions. | Parmar AS, Joshi M, Nosker PL, Hasan NF, Nanda V | Biomolecules | 24970200 | Biomolecules | 2013 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/24970200 |
Dissecting Electrostatic Contributions to Folding and Self-Assembly Using Designed Multicomponent Peptide Systems. | Parmar AS, James JK, Grisham DR, Pike DH, Nanda V | Journal of the American Chemical Society | 26966815 | J Am Chem Soc | 2016 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/26966815 |
Computational design of a collagen A:B:C-type heterotrimer. | Xu F, Zahid S, Silva T, Nanda V | Journal of the American Chemical Society | 21902217 | J Am Chem Soc | 2011 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/21902217 |
Circular permutation directs orthogonal assembly in complex collagen peptide mixtures. | Xu F, Silva T, Joshi M, Zahid S, Nanda V | The Journal of biological chemistry | 24043622 | J Biol Chem | 2013 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/24043622 |
Marginal protein stability drives subcellular proteome isoelectric point. | Loell K, Nanda V | Proceedings of the National Academy of Sciences of the United States of America | 30385634 | Proc Natl Acad Sci U S A | 2018 Nov 13 | https://www.ncbi.nlm.nih.gov/pubmed/30385634 |
Methacrylation induces rapid, temperature-dependent, reversible self-assembly of type-I collagen. | Drzewiecki KE, Parmar AS, Gaudet ID, Branch JR, Pike DH, Nanda V, Shreiber DI | Langmuir : the ACS journal of surfaces and colloids | 25208340 | Langmuir | 2014 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/25208340 |
Design of net-charged abc-type collagen heterotrimers. | Parmar AS, Zahid S, Belure SV, Young R, Hasan N, Nanda V | Journal of structural biology | 23603270 | J Struct Biol | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23603270 |
Empirical estimation of local dielectric constants: Toward atomistic design of collagen mimetic peptides. | Pike DH, Nanda V | Biopolymers | 25784456 | Biopolymers | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25784456 |
Hydrodynamic radius coincides with the slip plane position in the electrokinetic behavior of lysozyme. | Grisham DR, Nanda V | Proteins | 29383755 | Proteins | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29383755 |
Parallels between DNA and collagen - comparing elastic models of the double and triple helix. | Xu F, Zheng H, Clauvelin N, Lu XJ, Olson WK, Nanda V | Scientific reports | 29038480 | Sci Rep | 2017 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/29038480 |
De novo self-assembling collagen heterotrimers using explicit positive and negative design. | Xu F, Zhang L, Koder RL, Nanda V | Biochemistry | 20170197 | Biochemistry | 2010 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/20170197 |
Sequence recombination improves target specificity in a redesigned collagen peptide abc-type heterotrimer. | Giddu S, Xu F, Nanda V | Proteins | 23042255 | Proteins | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23042255 |
Morphological diversity and polymorphism of self-assembling collagen peptides controlled by length of hydrophobic domains. | McGuinness K, Khan IJ, Nanda V | ACS nano | 25390880 | ACS Nano | 2014 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/25390880 |
Compositional control of higher order assembly using synthetic collagen peptides. | Xu F, Li J, Jain V, Tu RS, Huang Q, Nanda V | Journal of the American Chemical Society | 22171825 | J Am Chem Soc | 2012 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/22171825 |
Self-assembly of left- and right-handed molecular screws. | Xu F, Khan IJ, McGuinness K, Parmar AS, Silva T, Murthy NS, Nanda V | Journal of the American Chemical Society | 24283407 | J Am Chem Soc | 2013 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/24283407 |
Molecular Self-Assembly Strategy for Generating Catalytic Hybrid Polypeptides. | Maeda Y, Fang J, Ikezoe Y, Pike DH, Nanda V, Matsui H | PloS one | 27116246 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27116246 |
Zeta Potential Prediction from Protein Structure in General Aqueous Electrolyte Solutions. | Grisham DR, Nanda V | Langmuir : the ACS journal of surfaces and colloids | 33186035 | Langmuir | 2020 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/33186035 |
Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124. | Kuhnert F, Mancuso MR, Shamloo A, Wang HT, Choksi V, Florek M, Su H, Fruttiger M, Young WL, Heilshorn SC, Kuo CJ | Science (New York, N.Y.) | 21071672 | Science | 2010 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/21071672 |
Protein-engineered biomaterials to generate human skeletal muscle mimics. | Sengupta D, Gilbert PM, Johnson KJ, Blau HM, Heilshorn SC | Advanced healthcare materials | 23184832 | Adv Healthc Mater | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23184832 |
Hydrogel crosslinking density regulates temporal contractility of human embryonic stem cell-derived cardiomyocytes in 3D cultures. | Chung C, Anderson E, Pera RR, Pruitt BL, Heilshorn SC | Soft matter | 23226161 | Soft Matter | 2012 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/23226161 |
Protein-engineered scaffolds for in vitro 3D culture of primary adult intestinal organoids. | DiMarco RL, Dewi RE, Bernal G, Kuo C, Heilshorn SC | Biomaterials science | 26371971 | Biomater Sci | 2015 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/26371971 |
Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells. | Cai L, Dewi RE, Heilshorn SC | Advanced functional materials | 26273242 | Adv Funct Mater | 2015 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/26273242 |
Microfluidic analysis of extracellular matrix-bFGF crosstalk on primary human myoblast chemoproliferation, chemokinesis, and chemotaxis. | Ferreira MM, Dewi RE, Heilshorn SC | Integrative biology : quantitative biosciences from nano to macro | 25909157 | Integr Biol (Camb) | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25909157 |
Complex chemoattractive and chemorepellent Kit signals revealed by direct imaging of murine mast cells in microfluidic gradient chambers. | Shamloo A, Manchandia M, Ferreira M, Mani M, Nguyen C, Jahn T, Weinberg K, Heilshorn S | Integrative biology : quantitative biosciences from nano to macro | 23835699 | Integr Biol (Camb) | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23835699 |
Adaptable hydrogel networks with reversible linkages for tissue engineering. | Wang H, Heilshorn SC | Advanced materials (Deerfield Beach, Fla.) | 25989348 | Adv Mater | 2015 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/25989348 |
Protein-engineered hydrogel encapsulation for 3-D culture of murine cochlea. | Chang DT, Chai R, DiMarco R, Heilshorn SC, Cheng AG | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology | 25111520 | Otol Neurotol | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25111520 |
Designing ECM-mimetic materials using protein engineering. | Cai L, Heilshorn SC | Acta biomaterialia | 24365704 | Acta Biomater | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24365704 |
Molecular-level engineering of protein physical hydrogels for predictive sol-gel phase behavior. | Mulyasasmita W, Lee JS, Heilshorn SC | Biomacromolecules | 21861461 | Biomacromolecules | 2011 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/21861461 |
Avidity-controlled delivery of angiogenic peptides from injectable molecular-recognition hydrogels. | Mulyasasmita W, Cai L, Hori Y, Heilshorn SC | Tissue engineering. Part A | 24490588 | Tissue Eng Part A | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24490588 |
Engineering of three-dimensional microenvironments to promote contractile behavior in primary intestinal organoids. | DiMarco RL, Su J, Yan KS, Dewi R, Kuo CJ, Heilshorn SC | Integrative biology : quantitative biosciences from nano to macro | 24343706 | Integr Biol (Camb) | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24343706 |
Avidity-controlled hydrogels for injectable co-delivery of induced pluripotent stem cell-derived endothelial cells and growth factors. | Mulyasasmita W, Cai L, Dewi RE, Jha A, Ullmann SD, Luong RH, Huang NF, Heilshorn SC | Journal of controlled release : official journal of the Controlled Release Society | 24848744 | J Control Release | 2014 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/24848744 |
Matrix density mediates polarization and lumen formation of endothelial sprouts in VEGF gradients. | Shamloo A, Heilshorn SC | Lab on a chip | 20820484 | Lab Chip | 2010 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/20820484 |
Microfluidic investigation of BDNF-enhanced neural stem cell chemotaxis in CXCL12 gradients. | Xu H, Heilshorn SC | Small (Weinheim an der Bergstrasse, Germany) | 23109183 | Small | 2013 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/23109183 |
Design of three-dimensional engineered protein hydrogels for tailored control of neurite growth. | Lampe KJ, Antaris AL, Heilshorn SC | Acta biomaterialia | 23128159 | Acta Biomater | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23128159 |
Mechanisms of vascular endothelial growth factor-induced pathfinding by endothelial sprouts in biomaterials. | Shamloo A, Xu H, Heilshorn S | Tissue engineering. Part A | 21888475 | Tissue Eng Part A | 2012 Feb | https://www.ncbi.nlm.nih.gov/pubmed/21888475 |
A microfluidic-based genetic screen to identify microbial virulence factors that inhibit dendritic cell migration. | McLaughlin LM, Xu H, Carden SE, Fisher S, Reyes M, Heilshorn SC, Monack DM | Integrative biology : quantitative biosciences from nano to macro | 24599496 | Integr Biol (Camb) | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24599496 |
One-pot Synthesis of Elastin-like Polypeptide Hydrogels with Grafted VEGF-Mimetic Peptides. | Cai L, Dinh CB, Heilshorn SC | Biomaterials science | 24729868 | Biomater Sci | 2014 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/24729868 |
Hybrid elastin-like polypeptide-polyethylene glycol (ELP-PEG) hydrogels with improved transparency and independent control of matrix mechanics and cell ligand density. | Wang H, Cai L, Paul A, Enejder A, Heilshorn SC | Biomacromolecules | 25111283 | Biomacromolecules | 2014 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/25111283 |
Small-molecule axon-polarization studies enabled by a shear-free microfluidic gradient generator. | Xu H, Ferreira MM, Heilshorn SC | Lab on a chip | 24781157 | Lab Chip | 2014 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/24781157 |
Sequence-specific crosslinking of electrospun, elastin-like protein preserves bioactivity and native-like mechanics. | Benitez PL, Sweet JA, Fink H, Chennazhi KP, Nair SV, Enejder A, Heilshorn SC | Advanced healthcare materials | 23184558 | Adv Healthc Mater | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23184558 |
Building stem cell niches from the molecule up through engineered peptide materials. | Lampe KJ, Heilshorn SC | Neuroscience letters | 22322073 | Neurosci Lett | 2012 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/22322073 |
Multifunctional materials through modular protein engineering. | DiMarco RL, Heilshorn SC | Advanced materials (Deerfield Beach, Fla.) | 22730248 | Adv Mater | 2012 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/22730248 |
Matrix interactions modulate neurotrophin-mediated neurite outgrowth and pathfinding. | Madl CM, Heilshorn SC | Neural regeneration research | 26170800 | Neural Regen Res | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26170800 |
Matrix RGD ligand density and L1CAM-mediated Schwann cell interactions synergistically enhance neurite outgrowth. | Romano NH, Madl CM, Heilshorn SC | Acta biomaterialia | 25308870 | Acta Biomater | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25308870 |
Chemotaxis of human induced pluripotent stem cell-derived endothelial cells. | Huang NF, Dewi RE, Okogbaa J, Lee JC, Jalilrufaihah A, Heilshorn SC, Cooke JP | American journal of translational research | 23977410 | Am J Transl Res | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23977410 |
Tetrakis(hydroxymethyl) phosphonium chloride as a covalent cross-linking agent for cell encapsulation within protein-based hydrogels. | Chung C, Lampe KJ, Heilshorn SC | Biomacromolecules | 23151175 | Biomacromolecules | 2012 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/23151175 |
Protein-engineered injectable hydrogel to improve retention of transplanted adipose-derived stem cells. | Parisi-Amon A, Mulyasasmita W, Chung C, Heilshorn SC | Advanced healthcare materials | 23184882 | Adv Healthc Mater | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23184882 |
Spontaneous cardiomyocyte differentiation of mouse embryoid bodies regulated by hydrogel crosslink density. | Chung C, Pruitt BL, Heilshorn SC | Biomaterials science | 24748962 | Biomater Sci | 2013 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/24748962 |
Photoreactive elastin-like proteins for use as versatile bioactive materials and surface coatings. | Raphel J, Parisi-Amon A, Heilshorn S | Journal of materials chemistry | 23015764 | J Mater Chem | 2012 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/23015764 |
Protein-engineered biomaterials: nanoscale mimics of the extracellular matrix. | Romano NH, Sengupta D, Chung C, Heilshorn SC | Biochimica et biophysica acta | 20647034 | Biochim Biophys Acta | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20647034 |
Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers. | Aguado BA, Mulyasasmita W, Su J, Lampe KJ, Heilshorn SC | Tissue engineering. Part A | 22011213 | Tissue Eng Part A | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22011213 |
Microfluidic gradients reveal enhanced neurite outgrowth but impaired guidance within 3D matrices with high integrin ligand densities. | Romano NH, Lampe KJ, Xu H, Ferreira MM, Heilshorn SC | Small (Weinheim an der Bergstrasse, Germany) | 25315156 | Small | 2015 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/25315156 |
Robust Iterative Stimulation with Self-Antigens Overcomes CD8(+) T Cell Tolerance to Self- and Tumor Antigens. | Nelson CE, Thompson EA, Quarnstrom CF, Fraser KA, Seelig DM, Bhela S, Burbach BJ, Masopust D, Vezys V | Cell reports | 31533033 | Cell Rep | 2019 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/31533033 |
Shortened Intervals during Heterologous Boosting Preserve Memory CD8 T Cell Function but Compromise Longevity. | Thompson EA, Beura LK, Nelson CE, Anderson KG, Vezys V | Journal of immunology (Baltimore, Md. : 1950) | 26903479 | J Immunol | 2016 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/26903479 |
Cutting edge: generation of effector cells that localize to mucosal tissues and form resident memory CD8 T cells is controlled by mTOR. | Sowell RT, Rogozinska M, Nelson CE, Vezys V, Marzo AL | Journal of immunology (Baltimore, Md. : 1950) | 25070853 | J Immunol | 2014 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/25070853 |
Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade. | Pauken KE, Nelson CE, Martinov T, Spanier JA, Heffernan JR, Sahli NL, Quarnstrom CF, Osum KC, Schenkel JM, Jenkins MK, Blazar BR, Vezys V, Fife BT | Journal of immunology (Baltimore, Md. : 1950) | 25769925 | J Immunol | 2015 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/25769925 |
The Hippo signaling pathway and stem cell biology. | Ramos A, Camargo FD | Trends in cell biology | 22658639 | Trends Cell Biol | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22658639 |
Reprogramming responsiveness to checkpoint blockade in dysfunctional CD8 T cells. | Nelson CE, Mills LJ, McCurtain JL, Thompson EA, Seelig DM, Bhela S, Quarnstrom CF, Fife BT, Vezys V | Proceedings of the National Academy of Sciences of the United States of America | 30679280 | Proc Natl Acad Sci U S A | 2019 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/30679280 |
Clonal dynamics of native haematopoiesis. | Sun J, Ramos A, Chapman B, Johnnidis JB, Le L, Ho YJ, Klein A, Hofmann O, Camargo FD | Nature | 25296256 | Nature | 2014 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/25296256 |
Cellular binding of nanoparticles in the presence of serum proteins. | Doorley GW, Payne CK | Chemical communications (Cambridge, England) | 20886139 | Chem Commun (Camb) | 2011 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/20886139 |
Cellular binding of nanoparticles disrupts the membrane potential. | Warren EA, Payne CK | RSC advances | 25685328 | RSC Adv | 2015 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/25685328 |
Lysosome transport as a function of lysosome diameter. | Bandyopadhyay D, Cyphersmith A, Zapata JA, Kim YJ, Payne CK | PloS one | 24497985 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24497985 |
Secondary structure of corona proteins determines the cell surface receptors used by nanoparticles. | Fleischer CC, Payne CK | The journal of physical chemistry. B | 24779411 | J Phys Chem B | 2014 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/24779411 |
Single particle tracking as a method to resolve differences in highly colocalized proteins. | Szymanski CJ, Humphries WH 4th, Payne CK | The Analyst | 21283889 | Analyst | 2011 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/21283889 |
Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells. | Wilder CL, Walton C, Watson V, Stewart FAA, Johnson J, Peyton SR, Payne CK, Odero-Marah V, Platt MO | The international journal of biochemistry & cell biology | 27592448 | Int J Biochem Cell Biol | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27592448 |
Cellular Binding of Anionic Nanoparticles is Inhibited by Serum Proteins Independent of Nanoparticle Composition. | Fleischer CC, Kumar U, Payne CK | Biomaterials science | 23956836 | Biomater Sci | 2013 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/23956836 |
Endo-lysosomal vesicles positive for Rab7 and LAMP1 are terminal vesicles for the transport of dextran. | Humphries WH 4th, Szymanski CJ, Payne CK | PloS one | 22039519 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22039519 |
Membrane potential mediates the cellular binding of nanoparticles. | Shin EH, Li Y, Kumar U, Sureka HV, Zhang X, Payne CK | Nanoscale | 23698734 | Nanoscale | 2013 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/23698734 |
Nanoparticle-cell interactions: molecular structure of the protein corona and cellular outcomes. | Fleischer CC, Payne CK | Accounts of chemical research | 25014679 | Acc Chem Res | 2014 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/25014679 |
Impact of Serum Proteins on MRI Contrast Agents: Cellular Binding and T(2) relaxation. | Hill A, Payne CK | RSC advances | 25485101 | RSC Adv | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25485101 |
Nanoparticle surface charge mediates the cellular receptors used by protein-nanoparticle complexes. | Fleischer CC, Payne CK | The journal of physical chemistry. B | 22774860 | J Phys Chem B | 2012 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/22774860 |
Nanoparticles act as protein carriers during cellular internalization. | Doorley GW, Payne CK | Chemical communications (Cambridge, England) | 22328990 | Chem Commun (Camb) | 2012 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/22328990 |
Imaging lysosomal enzyme activity in live cells using self-quenched substrates. | Humphries WH 4th, Payne CK | Analytical biochemistry | 22387398 | Anal Biochem | 2012 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/22387398 |
Different cortical involvement pattern of generalized and localized spasms: a magnetoencephalography study. | Kakisaka Y, Gupta A, Wang ZI, Dubarry AS, Alexopoulos AV, Mosher JC, Burgess RC | Epilepsy & behavior : E&B | 21944062 | Epilepsy Behav | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21944062 |
Brain stimulation in the treatment of chronic neuropathic and non-cancerous pain. | Plow EB, Pascual-Leone A, Machado A | The journal of pain | 22484179 | J Pain | 2012 May | https://www.ncbi.nlm.nih.gov/pubmed/22484179 |
Effectiveness and neural mechanisms associated with tDCS delivered to premotor cortex in stroke rehabilitation: study protocol for a randomized controlled trial. | Plow EB, Cunningham DA, Beall E, Jones S, Wyant A, Bonnett C, Yue GH, Lowe M, Wang XF, Sakaie K, Machado A | Trials | 24119615 | Trials | 2013 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/24119615 |
Central neuromodulation for refractory pain. | Moore NZ, Lempka SF, Machado A | Neurosurgery clinics of North America | 24262901 | Neurosurg Clin N Am | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24262901 |
Deep brain stimulation of the ventral striatum/anterior limb of the internal capsule in thalamic pain syndrome: study protocol for a pilot randomized controlled trial. | Plow EB, Malone DA Jr, Machado A | Trials | 23902631 | Trials | 2013 Jul 31 | https://www.ncbi.nlm.nih.gov/pubmed/23902631 |
Functional Magnetic Resonance Imaging Correlates of Ventral Striatal Deep Brain Stimulation for Poststroke Pain. | Jones SE, Lempka SF, Gopalakrishnan R, Baker KB, Beall EB, Bhattacharyya P, Huang X, Lin J, Chen J, Lowe MJ, Malone DA, Machado AG | Neuromodulation : journal of the International Neuromodulation Society | 32744789 | Neuromodulation | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32744789 |
Clinical evidence for the utility of movement compensation algorithm in magnetoencephalography: successful localization during focal seizure. | Kakisaka Y, Wang ZI, Mosher JC, Dubarry AS, Alexopoulos AV, Enatsu R, Kotagal P, Burgess RC | Epilepsy research | 22503605 | Epilepsy Res | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22503605 |
Deep brain stimulation of the ventral striatal area for poststroke pain syndrome: a magnetoencephalography study. | Gopalakrishnan R, Burgess RC, Malone DA, Lempka SF, Gale JT, Floden DP, Baker KB, Machado AG | Journal of neurophysiology | 29384450 | J Neurophysiol | 2018 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/29384450 |
Magnetoencephalography correlate of EEG POSTS (positive occipital sharp transients of sleep). | Kakisaka Y, Wang ZI, Enatsu R, Dubarry AS, Mosher JC, Alexopoulos AV, Burgess RC | Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society | 23733086 | J Clin Neurophysiol | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23733086 |
Magnetoencephalography's higher sensitivity to epileptic spikes may elucidate the profile of electroencephalographically negative epileptic seizures. | Kakisaka Y, Wang ZI, Mosher JC, Nair DR, Alexopoulos AV, Burgess RC | Epilepsy & behavior : E&B | 22227034 | Epilepsy Behav | 2012 Feb | https://www.ncbi.nlm.nih.gov/pubmed/22227034 |
Randomized clinical trial of deep brain stimulation for poststroke pain. | Lempka SF, Malone DA Jr, Hu B, Baker KB, Wyant A, Ozinga JG 4th, Plow EB, Pandya M, Kubu CS, Ford PJ, Machado AG | Annals of neurology | 28380672 | Ann Neurol | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28380672 |
Challenges in Recruitment for the Study of Noninvasive Brain Stimulation in Stroke: Lessons from Deep Brain Stimulation. | Potter-Baker KA, Bonnett CE, Chabra P, Roelle S, Varnerin N, Cunningham DA, Sankarasubramanian V, Pundik S, Conforto AB, Machado AG, Plow EB | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | 26851211 | J Stroke Cerebrovasc Dis | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26851211 |
The use of contact heat evoked potential stimulator (CHEPS) in magnetoencephalography for pain research. | Gopalakrishnan R, Machado AG, Burgess RC, Mosher JC | Journal of neuroscience methods | 23994044 | J Neurosci Methods | 2013 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/23994044 |
Cerebral stimulation for the affective component of neuropathic pain. | Machado AG, Baker KB, Plow E, Malone DA | Neuromodulation : journal of the International Neuromodulation Society | 23094938 | Neuromodulation | 2013 Nov-Dec | https://www.ncbi.nlm.nih.gov/pubmed/23094938 |
Voxel-based morphometric MRI post-processing in MRI-negative focal cortical dysplasia followed by simultaneously recorded MEG and stereo-EEG. | Wang ZI, Jones SE, Ristic AJ, Wong C, Kakisaka Y, Jin K, Schneider F, Gonzalez-Martinez JA, Mosher JC, Nair D, Burgess RC, Najm IM, Alexopoulos AV | Epilepsy research | 22391138 | Epilepsy Res | 2012 Jun | https://www.ncbi.nlm.nih.gov/pubmed/22391138 |
A magnetoencephalography study of multi-modal processing of pain anticipation in primary sensory cortices. | Gopalakrishnan R, Burgess RC, Plow EB, Floden DP, Machado AG | Neuroscience | 26210576 | Neuroscience | 2015 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/26210576 |
Early event related fields during visually evoked pain anticipation. | Gopalakrishnan R, Burgess RC, Plow EB, Floden DP, Machado AG | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 26733321 | Clin Neurophysiol | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26733321 |
The integration of T cell migration, differentiation and function. | Masopust D, Schenkel JM | Nature reviews. Immunology | 23598650 | Nat Rev Immunol | 2013 May | https://www.ncbi.nlm.nih.gov/pubmed/23598650 |
Preexisting high frequencies of memory CD8+ T cells favor rapid memory differentiation and preservation of proliferative potential upon boosting. | Fraser KA, Schenkel JM, Jameson SC, Vezys V, Masopust D | Immunity | 23890070 | Immunity | 2013 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/23890070 |
Intravascular staining for discrimination of vascular and tissue leukocytes. | Anderson KG, Mayer-Barber K, Sung H, Beura L, James BR, Taylor JJ, Qunaj L, Griffith TS, Vezys V, Barber DL, Masopust D | Nature protocols | 24385150 | Nat Protoc | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24385150 |
T cell memory. Resident memory CD8 T cells trigger protective innate and adaptive immune responses. | Schenkel JM, Fraser KA, Beura LK, Pauken KE, Vezys V, Masopust D | Science (New York, N.Y.) | 25170049 | Science | 2014 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/25170049 |
Sensing and alarm function of resident memory CD8⁺ T cells. | Schenkel JM, Fraser KA, Vezys V, Masopust D | Nature immunology | 23542740 | Nat Immunol | 2013 May | https://www.ncbi.nlm.nih.gov/pubmed/23542740 |
Cutting edge: resident memory CD8 T cells occupy frontline niches in secondary lymphoid organs. | Schenkel JM, Fraser KA, Masopust D | Journal of immunology (Baltimore, Md. : 1950) | 24600038 | J Immunol | 2014 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24600038 |
The molecular origins of chiral growth in walled cells. | Huang KC, Ehrhardt DW, Shaevitz JW | Current opinion in microbiology | 23194654 | Curr Opin Microbiol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23194654 |
Helical insertion of peptidoglycan produces chiral ordering of the bacterial cell wall. | Wang S, Furchtgott L, Huang KC, Shaevitz JW | Proceedings of the National Academy of Sciences of the United States of America | 22343529 | Proc Natl Acad Sci U S A | 2012 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/22343529 |
Posttranslational acetylation of α-tubulin constrains protofilament number in native microtubules. | Cueva JG, Hsin J, Huang KC, Goodman MB | Current biology : CB | 22658592 | Curr Biol | 2012 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/22658592 |
Interplay between the localization and kinetics of phosphorylation in flagellar pole development of the bacterium Caulobacter crescentus. | Tropini C, Huang KC | PLoS computational biology | 22876167 | PLoS Comput Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22876167 |
Mechanics of membrane bulging during cell-wall disruption in gram-negative bacteria. | Daly KE, Huang KC, Wingreen NS, Mukhopadhyay R | Physical review. E, Statistical, nonlinear, and soft matter physics | 21599215 | Phys Rev E Stat Nonlin Soft Matter Phys | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21599215 |
Physics of Intracellular Organization in Bacteria. | Wingreen NS, Huang KC | Annual review of microbiology | 26488278 | Annu Rev Microbiol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26488278 |
Bacterial division. Mechanical crack propagation drives millisecond daughter cell separation in Staphylococcus aureus. | Zhou X, Halladin DK, Rojas ER, Koslover EF, Lee TK, Huang KC, Theriot JA | Science (New York, N.Y.) | 25931560 | Science | 2015 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/25931560 |
FtsZ-Dependent Elongation of a Coccoid Bacterium. | Pereira AR, Hsin J, Król E, Tavares AC, Flores P, Hoiczyk E, Ng N, Dajkovic A, Brun YV, VanNieuwenhze MS, Roemer T, Carballido-Lopez R, Scheffers DJ, Huang KC, Pinho MG | mBio | 27601570 | mBio | 2016 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/27601570 |
Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells. | Lee TK, Meng K, Shi H, Huang KC | Nature communications | 27774981 | Nat Commun | 2016 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/27774981 |
GTPase activity-coupled treadmilling of the bacterial tubulin FtsZ organizes septal cell wall synthesis. | Yang X, Lyu Z, Miguel A, McQuillen R, Huang KC, Xiao J | Science (New York, N.Y.) | 28209899 | Science | 2017 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/28209899 |
Strain Library Imaging Protocol for high-throughput, automated single-cell microscopy of large bacterial collections arrayed on multiwell plates. | Shi H, Colavin A, Lee TK, Huang KC | Nature protocols | 28125106 | Nat Protoc | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/28125106 |
Motility enhancement through surface modification is sufficient for cyanobacterial community organization during phototaxis. | Ursell T, Chau RM, Wisen S, Bhaya D, Huang KC | PLoS computational biology | 24039562 | PLoS Comput Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24039562 |
A dynamically assembled cell wall synthesis machinery buffers cell growth. | Lee TK, Tropini C, Hsin J, Desmarais SM, Ursell TS, Gong E, Gitai Z, Monds RD, Huang KC | Proceedings of the National Academy of Sciences of the United States of America | 24550500 | Proc Natl Acad Sci U S A | 2014 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/24550500 |
Rod-like bacterial shape is maintained by feedback between cell curvature and cytoskeletal localization. | Ursell TS, Nguyen J, Monds RD, Colavin A, Billings G, Ouzounov N, Gitai Z, Shaevitz JW, Huang KC | Proceedings of the National Academy of Sciences of the United States of America | 24550515 | Proc Natl Acad Sci U S A | 2014 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/24550515 |
Cutting the Gordian Knot of the Microbiota. | Vasquez KS, Shiver AL, Huang KC | Molecular cell | 29883604 | Mol Cell | 2018 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/29883604 |
How to Build a Bacterial Cell: MreB as the Foreman of E. coli Construction. | Shi H, Bratton BP, Gitai Z, Huang KC | Cell | 29522748 | Cell | 2018 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/29522748 |
Response of Escherichia coli growth rate to osmotic shock. | Rojas E, Theriot JA, Huang KC | Proceedings of the National Academy of Sciences of the United States of America | 24821776 | Proc Natl Acad Sci U S A | 2014 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/24821776 |
Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance. | Aranda-Díaz A, Obadia B, Dodge R, Thomsen T, Hallberg ZF, Güvener ZT, Ludington WB, Huang KC | eLife | 31995029 | Elife | 2020 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/31995029 |
Macromolecules that prefer their membranes curvy. | Huang KC, Ramamurthi KS | Molecular microbiology | 20444099 | Mol Microbiol | 2010 May | https://www.ncbi.nlm.nih.gov/pubmed/20444099 |
Dynamic SpoIIIE assembly mediates septal membrane fission during Bacillus subtilis sporulation. | Fleming TC, Shin JY, Lee SH, Becker E, Huang KC, Bustamante C, Pogliano K | Genes & development | 20516200 | Genes Dev | 2010 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/20516200 |
Effects of polymerization and nucleotide identity on the conformational dynamics of the bacterial actin homolog MreB. | Colavin A, Hsin J, Huang KC | Proceedings of the National Academy of Sciences of the United States of America | 24550504 | Proc Natl Acad Sci U S A | 2014 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/24550504 |
Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium. | Chen YE, Tropini C, Jonas K, Tsokos CG, Huang KC, Laub MT | Proceedings of the National Academy of Sciences of the United States of America | 21191097 | Proc Natl Acad Sci U S A | 2011 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/21191097 |
Mechanisms for maintaining cell shape in rod-shaped Gram-negative bacteria. | Furchtgott L, Wingreen NS, Huang KC | Molecular microbiology | 21501250 | Mol Microbiol | 2011 Jul | https://www.ncbi.nlm.nih.gov/pubmed/21501250 |
Analysis of surface protein expression reveals the growth pattern of the gram-negative outer membrane. | Ursell TS, Trepagnier EH, Huang KC, Theriot JA | PLoS computational biology | 23028278 | PLoS Comput Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23028278 |
How and why cells grow as rods. | Chang F, Huang KC | BMC biology | 25185019 | BMC Biol | 2014 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/25185019 |
De novo morphogenesis in L-forms via geometric control of cell growth. | Billings G, Ouzounov N, Ursell T, Desmarais SM, Shaevitz J, Gitai Z, Huang KC | Molecular microbiology | 24995493 | Mol Microbiol | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/24995493 |
Recovery of the Gut Microbiota after Antibiotics Depends on Host Diet, Community Context, and Environmental Reservoirs. | Ng KM, Aranda-Díaz A, Tropini C, Frankel MR, Van Treuren W, O'Loughlin CT, Merrill BD, Yu FB, Pruss KM, Oliveira RA, Higginbottom SK, Neff NF, Fischbach MA, Xavier KB, Sonnenburg JL, Huang KC | Cell host & microbe | 31726029 | Cell Host Microbe | 2019 Nov 13 | https://www.ncbi.nlm.nih.gov/pubmed/31726029 |
Nucleotide-dependent conformations of FtsZ dimers and force generation observed through molecular dynamics simulations. | Hsin J, Gopinathan A, Huang KC | Proceedings of the National Academy of Sciences of the United States of America | 22647609 | Proc Natl Acad Sci U S A | 2012 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/22647609 |
Peptidoglycan at its peaks: how chromatographic analyses can reveal bacterial cell wall structure and assembly. | Desmarais SM, De Pedro MA, Cava F, Huang KC | Molecular microbiology | 23679048 | Mol Microbiol | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23679048 |
How Does the Xenopus laevis Embryonic Cell Cycle Avoid Spatial Chaos? | Gelens L, Huang KC, Ferrell JE Jr | Cell reports | 26212326 | Cell Rep | 2015 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/26212326 |
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. | Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CHS, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA | Cell | 27238023 | Cell | 2016 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/27238023 |
Homeostatic Cell Growth Is Accomplished Mechanically through Membrane Tension Inhibition of Cell-Wall Synthesis. | Rojas ER, Huang KC, Theriot JA | Cell systems | 29203279 | Cell Syst | 2017 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/29203279 |
Isolation and preparation of bacterial cell walls for compositional analysis by ultra performance liquid chromatography. | Desmarais SM, Cava F, de Pedro MA, Huang KC | Journal of visualized experiments : JoVE | 24457605 | J Vis Exp | 2014 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/24457605 |
The contractile ring coordinates curvature-dependent septum assembly during fission yeast cytokinesis. | Zhou Z, Munteanu EL, He J, Ursell T, Bathe M, Huang KC, Chang F | Molecular biology of the cell | 25355954 | Mol Biol Cell | 2015 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/25355954 |
Principles of bacterial cell-size determination revealed by cell-wall synthesis perturbations. | Tropini C, Lee TK, Hsin J, Desmarais SM, Ursell T, Monds RD, Huang KC | Cell reports | 25456140 | Cell Rep | 2014 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/25456140 |
Chiral twisting in a bacterial cytoskeletal polymer affects filament size and orientation. | Shi H, Quint DA, Grason GM, Gopinathan A, Huang KC | Nature communications | 32179732 | Nat Commun | 2020 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/32179732 |
High-throughput, Highly Sensitive Analyses of Bacterial Morphogenesis Using Ultra Performance Liquid Chromatography. | Desmarais SM, Tropini C, Miguel A, Cava F, Monds RD, de Pedro MA, Huang KC | The Journal of biological chemistry | 26468288 | J Biol Chem | 2015 Dec 25 | https://www.ncbi.nlm.nih.gov/pubmed/26468288 |
RodZ modulates geometric localization of the bacterial actin MreB to regulate cell shape. | Colavin A, Shi H, Huang KC | Nature communications | 29599448 | Nat Commun | 2018 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/29599448 |
The role of hydrolases in bacterial cell-wall growth. | Lee TK, Huang KC | Current opinion in microbiology | 24035761 | Curr Opin Microbiol | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24035761 |
FtsZ protofilaments use a hinge-opening mechanism for constrictive force generation. | Li Y, Hsin J, Zhao L, Cheng Y, Shang W, Huang KC, Wang HW, Ye S | Science (New York, N.Y.) | 23888039 | Science | 2013 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/23888039 |
Dimer dynamics and filament organization of the bacterial cell division protein FtsA. | Hsin J, Fu R, Huang KC | Journal of molecular biology | 23871894 | J Mol Biol | 2013 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/23871894 |
Optimal dynamics for quality control in spatially distributed mitochondrial networks. | Patel PK, Shirihai O, Huang KC | PLoS computational biology | 23874166 | PLoS Comput Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23874166 |
Mechanical consequences of cell-wall turnover in the elongation of a Gram-positive bacterium. | Misra G, Rojas ER, Gopinathan A, Huang KC | Biophysical journal | 23746506 | Biophys J | 2013 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/23746506 |
Physical constraints on the establishment of intracellular spatial gradients in bacteria. | Tropini C, Rabbani N, Huang KC | BMC biophysics | 22931750 | BMC Biophys | 2012 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/22931750 |
Does the potential for chaos constrain the embryonic cell-cycle oscillator? | McIsaac RS, Huang KC, Sengupta A, Wingreen NS | PLoS computational biology | 21779158 | PLoS Comput Biol | 2011 Jul | https://www.ncbi.nlm.nih.gov/pubmed/21779158 |
The bacterial actin MreB rotates, and rotation depends on cell-wall assembly. | van Teeffelen S, Wang S, Furchtgott L, Huang KC, Wingreen NS, Shaevitz JW, Gitai Z | Proceedings of the National Academy of Sciences of the United States of America | 21903929 | Proc Natl Acad Sci U S A | 2011 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/21903929 |
Systematic perturbation of cytoskeletal function reveals a linear scaling relationship between cell geometry and fitness. | Monds RD, Lee TK, Colavin A, Ursell T, Quan S, Cooper TF, Huang KC | Cell reports | 25456141 | Cell Rep | 2014 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/25456141 |
Multimodal magnetic core-shell nanoparticles for effective stem-cell differentiation and imaging. | Shah B, Yin PT, Ghoshal S, Lee KB | Angewandte Chemie (International ed. in English) | 23650180 | Angew Chem Int Ed Engl | 2013 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/23650180 |
Integrating epigenetic modulators into NanoScript for enhanced chondrogenesis of stem cells. | Patel S, Pongkulapa T, Yin PT, Pandian GN, Rathnam C, Bando T, Vaijayanthi T, Sugiyama H, Lee KB | Journal of the American Chemical Society | 25789886 | J Am Chem Soc | 2015 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/25789886 |
Versatile fluorescence resonance energy transfer-based mesoporous silica nanoparticles for real-time monitoring of drug release. | Lai J, Shah BP, Garfunkel E, Lee KB | ACS nano | 23445171 | ACS Nano | 2013 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/23445171 |
3D graphene oxide-encapsulated gold nanoparticles to detect neural stem cell differentiation. | Kim TH, Lee KB, Choi JW | Biomaterials | 23937915 | Biomaterials | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23937915 |
Guiding stem cell differentiation into oligodendrocytes using graphene-nanofiber hybrid scaffolds. | Shah S, Yin PT, Uehara TM, Chueng ST, Yang L, Lee KB | Advanced materials (Deerfield Beach, Fla.) | 24668911 | Adv Mater | 2014 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/24668911 |
Nanotechnology-Based Approaches for Guiding Neural Regeneration. | Shah S, Solanki A, Lee KB | Accounts of chemical research | 26653885 | Acc Chem Res | 2016 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/26653885 |
Photo-triggerable Hydrogel-Nanoparticle Hybrid Scaffolds for Remotely Controlled Drug Delivery. | Shah S, Sasmal PK, Lee KB | Journal of materials chemistry. B | 25580246 | J Mater Chem B | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25580246 |
Probing stem cell behavior using nanoparticle-based approaches. | Patel S, Lee KB | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 25903468 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2015 Nov-Dec | https://www.ncbi.nlm.nih.gov/pubmed/25903468 |
Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions. | Kamei K, Ohashi M, Gschweng E, Ho Q, Suh J, Tang J, For Yu ZT, Clark AT, Pyle AD, Teitell MA, Lee KB, Witte ON, Tseng HR | Lab on a chip | 20390128 | Lab Chip | 2010 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/20390128 |
Carbon nanotube monolayer cues for osteogenesis of mesenchymal stem cells. | Baik KY, Park SY, Heo K, Lee KB, Hong S | Small (Weinheim an der Bergstrasse, Germany) | 21425459 | Small | 2011 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/21425459 |
Graphite-coated magnetic nanoparticles as multimodal imaging probes and cooperative therapeutic agents for tumor cells. | Park JK, Jung J, Subramaniam P, Shah BP, Kim C, Lee JK, Cho JH, Lee C, Lee KB | Small (Weinheim an der Bergstrasse, Germany) | 21560243 | Small | 2011 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/21560243 |
Development of Photoactivated Fluorescent N-Hydroxyoxindoles and Their Application for Cell-Selective Imaging. | Lai J, Yu A, Yang L, Zhang Y, Shah BP, Lee KB | Chemistry (Weinheim an der Bergstrasse, Germany) | 27004772 | Chemistry | 2016 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/27004772 |
Inducing Stem Cell Myogenesis Using NanoScript. | Patel S, Yin PT, Sugiyama H, Lee KB | ACS nano | 26108385 | ACS Nano | 2015 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/26108385 |
Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex. | Liu H, Agam Y, Madsen JR, Kreiman G | Neuron | 19409272 | Neuron | 2009 Apr 30 | https://www.ncbi.nlm.nih.gov/pubmed/19409272 |
From neurons to circuits: linear estimation of local field potentials. | Rasch M, Logothetis NK, Kreiman G | The Journal of neuroscience : the official journal of the Society for Neuroscience | 19889990 | J Neurosci | 2009 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/19889990 |
Short temporal asynchrony disrupts visual object recognition. | Singer JM, Kreiman G | Journal of vision | 24819738 | J Vis | 2014 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/24819738 |
Robust selectivity to two-object images in human visual cortex. | Agam Y, Liu H, Papanastassiou A, Buia C, Golby AJ, Madsen JR, Kreiman G | Current biology : CB | 20417105 | Curr Biol | 2010 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/20417105 |
Mesoscopic physiological interactions in the human brain reveal small-world properties. | Wang J, Tao A, Anderson WS, Madsen JR, Kreiman G | Cell reports | 34433053 | Cell Rep | 2021 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/34433053 |
Theory on the coupled stochastic dynamics of transcription and splice-site recognition. | Murugan R, Kreiman G | PLoS computational biology | 23133354 | PLoS Comput Biol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23133354 |
Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. | Cohen S, Gabel HW, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME | Neuron | 21982370 | Neuron | 2011 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/21982370 |
Spatiotemporal dynamics underlying object completion in human ventral visual cortex. | Tang H, Buia C, Madhavan R, Crone NE, Madsen JR, Anderson WS, Kreiman G | Neuron | 25043420 | Neuron | 2014 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/25043420 |
Integrated genome analysis suggests that most conserved non-coding sequences are regulatory factor binding sites. | Hemberg M, Gray JM, Cloonan N, Kuersten S, Grimmond S, Greenberg ME, Kreiman G | Nucleic acids research | 22684627 | Nucleic Acids Res | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22684627 |
Toward unmasking the dynamics of visual perception. | Singer J, Kreiman G | Neuron | 19945387 | Neuron | 2009 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/19945387 |
Cascade of neural processing orchestrates cognitive control in human frontal cortex. | Tang H, Yu HY, Chou CC, Crone NE, Madsen JR, Anderson WS, Kreiman G | eLife | 26888070 | Elife | 2016 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/26888070 |
Can Deep Learning Recognize Subtle Human Activities? | Jacquot V, Ying Z, Kreiman G | Conference on Computer Vision and Pattern Recognition Workshops. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. Workshops | 34290902 | Conf Comput Vis Pattern Recognit Workshops | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34290902 |
Measuring sparseness in the brain: comment on Bowers (2009). | Quian Quiroga R, Kreiman G | Psychological review | 20063978 | Psychol Rev | 2010 Jan | https://www.ncbi.nlm.nih.gov/pubmed/20063978 |
How cortical neurons help us see: visual recognition in the human brain. | Blumberg J, Kreiman G | The Journal of clinical investigation | 20811161 | J Clin Invest | 2010 Sep | https://www.ncbi.nlm.nih.gov/pubmed/20811161 |
Neuroscience: what we cannot model, we do not understand. | Anderson WS, Kreiman G | Current biology : CB | 21300278 | Curr Biol | 2011 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/21300278 |
Widespread transcription at neuronal activity-regulated enhancers. | Kim TK, Hemberg M, Gray JM, Costa AM, Bear DM, Wu J, Harmin DA, Laptewicz M, Barbara-Haley K, Kuersten S, Markenscoff-Papadimitriou E, Kuhl D, Bito H, Worley PF, Kreiman G, Greenberg ME | Nature | 20393465 | Nature | 2010 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/20393465 |
Internally generated preactivation of single neurons in human medial frontal cortex predicts volition. | Fried I, Mukamel R, Kreiman G | Neuron | 21315264 | Neuron | 2011 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/21315264 |
Face recognition: vision and emotions beyond the bubble. | Tang H, Kreiman G | Current biology : CB | 22075428 | Curr Biol | 2011 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/22075428 |
Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro. | Young JL, Engler AJ | Biomaterials | 21071078 | Biomaterials | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/21071078 |
Cell instructive microporous scaffolds through interface engineering. | Viswanathan P, Chirasatitsin S, Ngamkham K, Engler AJ, Battaglia G | Journal of the American Chemical Society | 23163574 | J Am Chem Soc | 2012 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/23163574 |
Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength. | Vincent LG, Choi YS, Alonso-Latorre B, del Álamo JC, Engler AJ | Biotechnology journal | 23390141 | Biotechnol J | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23390141 |
Wet nanoscale imaging and testing of polymersomes. | Battaglia G, LoPresti C, Massignani M, Warren NJ, Madsen J, Forster S, Vasilev C, Hobbs JK, Armes SP, Chirasatitsin S, Engler AJ | Small (Weinheim an der Bergstrasse, Germany) | 21695783 | Small | 2011 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/21695783 |
Digital Plasmonic Patterning for Localized Tuning of Hydrogel Stiffness. | Hribar KC, Choi YS, Ondeck M, Engler AJ, Chen S | Advanced functional materials | 26120293 | Adv Funct Mater | 2014 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/26120293 |
3D surface topology guides stem cell adhesion and differentiation. | Viswanathan P, Ondeck MG, Chirasatitsin S, Ngamkham K, Reilly GC, Engler AJ, Battaglia G | Biomaterials | 25818420 | Biomaterials | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25818420 |
Epimuscular Fat in the Human Rotator Cuff Is a Novel Beige Depot. | Meyer GA, Gibbons MC, Sato E, Lane JG, Ward SR, Engler AJ | Stem cells translational medicine | 25999520 | Stem Cells Transl Med | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25999520 |
Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels. | Hadden WJ, Young JL, Holle AW, McFetridge ML, Kim DY, Wijesinghe P, Taylor-Weiner H, Wen JH, Lee AR, Bieback K, Vo BN, Sampson DD, Kennedy BF, Spatz JP, Engler AJ, Choi YS | Proceedings of the National Academy of Sciences of the United States of America | 28507138 | Proc Natl Acad Sci U S A | 2017 May 30 | https://www.ncbi.nlm.nih.gov/pubmed/28507138 |
High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. | Holle AW, McIntyre AJ, Kehe J, Wijesekara P, Young JL, Vincent LG, Engler AJ | Integrative biology : quantitative biosciences from nano to macro | 27723854 | Integr Biol (Camb) | 2016 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/27723854 |
Stimulation of adipogenesis of adult adipose-derived stem cells using substrates that mimic the stiffness of adipose tissue. | Young DA, Choi YS, Engler AJ, Christman KL | Biomaterials | 23953825 | Biomaterials | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23953825 |
Haptotaxis is cell type specific and limited by substrate adhesiveness. | Wen JH, Choi O, Taylor-Weiner H, Fuhrmann A, Karpiak JV, Almutairi A, Engler AJ | Cellular and molecular bioengineering | 26640598 | Cell Mol Bioeng | 2015 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/26640598 |
Nanoscopic mechanical anisotropy in hydrogel surfaces. | Flores-Merino MV, Chirasatitsin S, Lopresti C, Reilly GC, Battaglia G, Engler AJ | Soft matter | 20953281 | Soft Matter | 2010 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/20953281 |
Muscle progenitor cell regenerative capacity in the torn rotator cuff. | Meyer GA, Farris AL, Sato E, Gibbons M, Lane JG, Ward SR, Engler AJ | Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 25410765 | J Orthop Res | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25410765 |
Extracellular matrix regulation in the muscle satellite cell niche. | Thomas K, Engler AJ, Meyer GA | Connective tissue research | 25047058 | Connect Tissue Res | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25047058 |
Acute shear stress direction dictates adherent cell remodeling and verifies shear profile of spinning disk assays. | Fuhrmann A, Engler AJ | Physical biology | 25619322 | Phys Biol | 2015 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/25619322 |
Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan. | Sessions AO, Kaushik G, Parker S, Raedschelders K, Bodmer R, Van Eyk JE, Engler AJ | Matrix biology : journal of the International Society for Matrix Biology | 27793636 | Matrix Biol | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27793636 |
Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart. | Kaushik G, Spenlehauer A, Sessions AO, Trujillo AS, Fuhrmann A, Fu Z, Venkatraman V, Pohl D, Tuler J, Wang M, Lakatta EG, Ocorr K, Bodmer R, Bernstein SI, Van Eyk JE, Cammarato A, Engler AJ | Science translational medicine | 26084806 | Sci Transl Med | 2015 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/26084806 |
Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation. | Happe CL, Tenerelli KP, Gromova AK, Kolb F, Engler AJ | Molecular biology of the cell | 28495800 | Mol Biol Cell | 2017 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/28495800 |
Effect of platelet-rich plasma on degeneration change of rotator cuff muscles: In vitro and in vivo evaluations. | Takase F, Inui A, Mifune Y, Sakata R, Muto T, Harada Y, Ueda Y, Kokubu T, Kurosaka M | Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 27684960 | J Orthop Res | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27684960 |
In situ mechanical analysis of myofibrillar perturbation and aging on soft, bilayered Drosophila myocardium. | Kaushik G, Fuhrmann A, Cammarato A, Engler AJ | Biophysical journal | 22261050 | Biophys J | 2011 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/22261050 |
More than a feeling: discovering, understanding, and influencing mechanosensing pathways. | Holle AW, Engler AJ | Current opinion in biotechnology | 21536426 | Curr Opin Biotechnol | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21536426 |
Interplay of matrix stiffness and protein tethering in stem cell differentiation. | Wen JH, Vincent LG, Fuhrmann A, Choi YS, Hribar KC, Taylor-Weiner H, Chen S, Engler AJ | Nature materials | 25108614 | Nat Mater | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25108614 |
Stiffness gradients mimicking in vivo tissue variation regulate mesenchymal stem cell fate. | Tse JR, Engler AJ | PloS one | 21246050 | PLoS One | 2011 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/21246050 |
Detecting cell-adhesive sites in extracellular matrix using force spectroscopy mapping. | Chirasatitsin S, Engler AJ | Journal of physics. Condensed matter : an Institute of Physics journal | 21152375 | J Phys Condens Matter | 2010 May 19 | https://www.ncbi.nlm.nih.gov/pubmed/21152375 |
In situ mechanotransduction via vinculin regulates stem cell differentiation. | Holle AW, Tang X, Vijayraghavan D, Vincent LG, Fuhrmann A, Choi YS, del Álamo JC, Engler AJ | Stem cells (Dayton, Ohio) | 23897765 | Stem Cells | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23897765 |
A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function. | Viswanathan MC, Kaushik G, Engler AJ, Lehman W, Cammarato A | Circulation research | 24221941 | Circ Res | 2014 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/24221941 |
The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices. | Choi YS, Vincent LG, Lee AR, Kretchmer KC, Chirasatitsin S, Dobke MK, Engler AJ | Biomaterials | 22800539 | Biomaterials | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22800539 |
Traction forces mediated by integrin signaling are necessary for definitive endoderm specification. | Taylor-Weiner H, Ravi N, Engler AJ | Journal of cell science | 25908864 | J Cell Sci | 2015 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/25908864 |
Mechanical regulation of cardiac fibroblast profibrotic phenotypes. | Herum KM, Choppe J, Kumar A, Engler AJ, McCulloch AD | Molecular biology of the cell | 28468977 | Mol Biol Cell | 2017 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/28468977 |
RAP2 mediates mechanoresponses of the Hippo pathway. | Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL | Nature | 30135582 | Nature | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30135582 |
A co-culture device with a tunable stiffness to understand combinatorial cell-cell and cell-matrix interactions. | Rao N, Grover GN, Vincent LG, Evans SC, Choi YS, Spencer KH, Hui EE, Engler AJ, Christman KL | Integrative biology : quantitative biosciences from nano to macro | 24061208 | Integr Biol (Camb) | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24061208 |
Dynamic and reversible surface topography influences cell morphology. | Kiang JD, Wen JH, del Álamo JC, Engler AJ | Journal of biomedical materials research. Part A | 23355509 | J Biomed Mater Res A | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23355509 |
Materials as stem cell regulators. | Murphy WL, McDevitt TC, Engler AJ | Nature materials | 24845994 | Nat Mater | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24845994 |
Cation type specific cell remodeling regulates attachment strength. | Fuhrmann A, Li J, Chien S, Engler AJ | PloS one | 25014042 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25014042 |
Mechanical Characterization of a Dynamic and Tunable Methacrylated Hyaluronic Acid Hydrogel. | Ondeck MG, Engler AJ | Journal of biomechanical engineering | 26746491 | J Biomech Eng | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26746491 |
Rotator cuff tear state modulates self-renewal and differentiation capacity of human skeletal muscle progenitor cells. | Thomas KA, Gibbons MC, Lane JG, Singh A, Ward SR, Engler AJ | Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 27699827 | J Orthop Res | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27699827 |
Metastatic State of Cancer Cells May Be Indicated by Adhesion Strength. | Fuhrmann A, Banisadr A, Beri P, Tlsty TD, Engler AJ | Biophysical journal | 28256233 | Biophys J | 2017 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/28256233 |
Mechanical derivation of functional myotubes from adipose-derived stem cells. | Choi YS, Vincent LG, Lee AR, Dobke MK, Engler AJ | Biomaterials | 22197570 | Biomaterials | 2012 Mar | https://www.ncbi.nlm.nih.gov/pubmed/22197570 |
The cytoskeleton regulates cell attachment strength. | Fuhrmann A, Engler AJ | Biophysical journal | 26153702 | Biophys J | 2015 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/26153702 |
A doublet microlens array for imaging micron-sized objects. | Tripathi A, Chronis N | Journal of micromechanics and microengineering : structures, devices, and systems | 22003271 | J Micromech Microeng | 2011 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/22003271 |
Chemically induced oxidative stress affects ASH neuronal function and behavior in C. elegans. | Gourgou E, Chronis N | Scientific reports | 27922032 | Sci Rep | 2016 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/27922032 |
A Biochip with a 3D microfluidic architecture for trapping white blood cells. | Tripathi A, Riddell J 4th, Chronis N | Sensors and actuators. B, Chemical | 23935241 | Sens Actuators B Chem | 2013 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/23935241 |
An automated compound screening for anti-aging effects on the function of C. elegans sensory neurons. | Bazopoulou D, Chaudhury AR, Pantazis A, Chronis N | Scientific reports | 28839194 | Sci Rep | 2017 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/28839194 |
Global hormone profiling of murine placenta reveals Secretin expression. | Knox K, Leuenberger D, Penn AA, Baker JC | Placenta | 21944867 | Placenta | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21944867 |
Plasma vasopressin concentrations positively predict cerebrospinal fluid vasopressin concentrations in human neonates. | Carson DS, Howerton CL, Garner JP, Hyde SA, Clark CL, Hardan AY, Penn AA, Parker KJ | Peptides | 25148831 | Peptides | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25148831 |
Correlation of preterm infant illness severity with placental histology. | Chisholm KM, Heerema-McKenney A, Tian L, Rajani AK, Saria S, Koller D, Penn AA | Placenta | 26992676 | Placenta | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26992676 |
Integration of early physiological responses predicts later illness severity in preterm infants. | Saria S, Rajani AK, Gould J, Koller D, Penn AA | Science translational medicine | 20826840 | Sci Transl Med | 2010 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/20826840 |
Is infection a factor in neonatal encephalopathy? | Nelson KB, Penn AA | Archives of disease in childhood. Fetal and neonatal edition | 25169244 | Arch Dis Child Fetal Neonatal Ed | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25169244 |
Sex-specific cognitive deficits and regional brain volume loss in mice exposed to chronic, sublethal hypoxia. | Lan WC, Priestley M, Mayoral SR, Tian L, Shamloo M, Penn AA | Pediatric research | 21436761 | Pediatr Res | 2011 Jul | https://www.ncbi.nlm.nih.gov/pubmed/21436761 |
Neonatal CSF oxytocin levels are associated with parent report of infant soothability and sociability. | Clark CL, St John N, Pasca AM, Hyde SA, Hornbeak K, Abramova M, Feldman H, Parker KJ, Penn AA | Psychoneuroendocrinology | 23507187 | Psychoneuroendocrinology | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23507187 |
Sex differences in a hypoxia model of preterm brain damage. | Mayoral SR, Omar G, Penn AA | Pediatric research | 19542909 | Pediatr Res | 2009 Sep | https://www.ncbi.nlm.nih.gov/pubmed/19542909 |
Controversies in preterm brain injury. | Penn AA, Gressens P, Fleiss B, Back SA, Gallo V | Neurobiology of disease | 26477300 | Neurobiol Dis | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26477300 |
Placental function assessed visually using half-Fourier acquisition single-shot turbo spin-echo (HASTE) magnetic resonance imaging. | Himoto Y, Kido A, Mogami H, Moribata Y, Minamiguchi S, Shitano F, Kiguchi K, Kurata Y, Konishi I, Togashi K | Placenta | 26992675 | Placenta | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26992675 |
Dynamic assessment of baroreflex control of heart rate during induction of propofol anesthesia using a point process method. | Chen Z, Purdon PL, Harrell G, Pierce ET, Walsh J, Brown EN, Barbieri R | Annals of biomedical engineering | 20945159 | Ann Biomed Eng | 2011 Jan | https://www.ncbi.nlm.nih.gov/pubmed/20945159 |
A fast iterative greedy algorithm for MEG source localization. | Obregon-Henao G, Babadi B, Lamus C, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23367478 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23367478 |
A neurophysiological-metabolic model for burst suppression. | Ching S, Purdon PL, Vijayan S, Kopell NJ, Brown EN | Proceedings of the National Academy of Sciences of the United States of America | 22323592 | Proc Natl Acad Sci U S A | 2012 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/22323592 |
Phase-based measures of cross-frequency coupling in brain electrical dynamics under general anesthesia. | Mukamel EA, Wong KF, Prerau MJ, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22254722 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22254722 |
Reference-free removal of EEG-fMRI ballistocardiogram artifacts with harmonic regression. | Krishnaswamy P, Bonmassar G, Poulsen C, Pierce ET, Purdon PL, Brown EN | NeuroImage | 26151100 | Neuroimage | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26151100 |
The Ageing Brain: Age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia. | Purdon PL, Pavone KJ, Akeju O, Smith AC, Sampson AL, Lee J, Zhou DW, Solt K, Brown EN | British journal of anaesthesia | 26174300 | Br J Anaesth | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26174300 |
Age-dependency of sevoflurane-induced electroencephalogram dynamics in children. | Akeju O, Pavone KJ, Thum JA, Firth PG, Westover MB, Puglia M, Shank ES, Brown EN, Purdon PL | British journal of anaesthesia | 26174303 | Br J Anaesth | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26174303 |
Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants. | Cornelissen L, Kim SE, Purdon PL, Brown EN, Berde CB | eLife | 26102526 | Elife | 2015 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/26102526 |
Statistical modeling of behavioral dynamics during propofol-induced loss of consciousness. | Wong KF, Smith AC, Pierce ET, Harrell PG, Walsh JL, Salazar-Gómez AF, Tavares CL, Purdon PL, Brown EN | Journal of neuroscience methods | 24530701 | J Neurosci Methods | 2014 Apr 30 | https://www.ncbi.nlm.nih.gov/pubmed/24530701 |
An enhanced cerebral recovery index for coma prognostication following cardiac arrest. | Ghassemi MM, Amorim E, Pati SB, Mark RG, Brown EN, Purdon PL, Westover MB | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 26736317 | Annu Int Conf IEEE Eng Med Biol Soc | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26736317 |
A Prospective Study of Age-dependent Changes in Propofol-induced Electroencephalogram Oscillations in Children. | Lee JM, Akeju O, Terzakis K, Pavone KJ, Deng H, Houle TT, Firth PG, Shank ES, Brown EN, Purdon PL | Anesthesiology | 28657957 | Anesthesiology | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28657957 |
Computationally Efficient Algorithms for Sparse, Dynamic Solutions to the EEG Source Localization Problem. | Pirondini E, Babadi B, Obregon-Henao G, Lamus C, Malik WQ, Hamalainen MS, Purdon PL | IEEE transactions on bio-medical engineering | 28920892 | IEEE Trans Biomed Eng | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28920892 |
A transient cortical state with sleep-like sensory responses precedes emergence from general anesthesia in humans. | Lewis LD, Piantoni G, Peterfreund RA, Eskandar EN, Harrell PG, Akeju O, Aglio LS, Cash SS, Brown EN, Mukamel EA, Purdon PL | eLife | 30095069 | Elife | 2018 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/30095069 |
Real-time segmentation of burst suppression patterns in critical care EEG monitoring. | Brandon Westover M, Shafi MM, Ching S, Chemali JJ, Purdon PL, Cash SS, Brown EN | Journal of neuroscience methods | 23891828 | J Neurosci Methods | 2013 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/23891828 |
A spatiotemporal dynamic distributed solution to the MEG inverse problem. | Lamus C, Hämäläinen MS, Temereanca S, Brown EN, Purdon PL | NeuroImage | 22155043 | Neuroimage | 2012 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/22155043 |
Bayesian analysis of trinomial data in behavioral experiments and its application to human studies of general anesthesia. | Wong KF, Smith AC, Pierce ET, Harrell PG, Walsh JL, Salazar AF, Tavares CL, Cimenser A, Prerau MJ, Mukamel EA, Sampson A, Purdon PL, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22255388 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22255388 |
Local cortical dynamics of burst suppression in the anaesthetized brain. | Lewis LD, Ching S, Weiner VS, Peterfreund RA, Eskandar EN, Cash SS, Brown EN, Purdon PL | Brain : a journal of neurology | 23887187 | Brain | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23887187 |
Electroencephalographic markers of brain development during sevoflurane anaesthesia in children up to 3 years old. | Cornelissen L, Kim SE, Lee JM, Brown EN, Purdon PL, Berde CB | British journal of anaesthesia | 29793594 | Br J Anaesth | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29793594 |
Biophysical Modeling of Alpha Rhythms During Halothane-Induced Unconsciousness. | Vijayan S, Ching S, Purdon PL, Brown EN, Kopell NJ | International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering | 25284633 | Int IEEE EMBS Conf Neural Eng | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/25284633 |
A comparison of propofol- and dexmedetomidine-induced electroencephalogram dynamics using spectral and coherence analysis. | Akeju O, Pavone KJ, Westover MB, Vazquez R, Prerau MJ, Harrell PG, Hartnack KE, Rhee J, Sampson AL, Habeeb K, Gao L, Pierce ET, Walsh JL, Brown EN, Purdon PL | Anesthesiology | 25187999 | Anesthesiology | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25187999 |
The human burst suppression electroencephalogram of deep hypothermia. | Westover MB, Ching S, Kumaraswamy VM, Akeju SO, Pierce E, Cash SS, Kilbride R, Brown EN, Purdon PL | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 25649968 | Clin Neurophysiol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25649968 |
Burst suppression probability algorithms: state-space methods for tracking EEG burst suppression. | Chemali J, Ching S, Purdon PL, Solt K, Brown EN | Journal of neural engineering | 24018288 | J Neural Eng | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24018288 |
Effects of sevoflurane and propofol on frontal electroencephalogram power and coherence. | Akeju O, Westover MB, Pavone KJ, Sampson AL, Hartnack KE, Brown EN, Purdon PL | Anesthesiology | 25233374 | Anesthesiology | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25233374 |
Beamforming approach to phase-amplitude modulation analysis of multi-channel EEG. | Sampson AL, Babadi B, Prerau MJ, Mukamel EA, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23367474 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23367474 |
The aging brain and anesthesia. | Brown EN, Purdon PL | Current opinion in anaesthesiology | 23820102 | Curr Opin Anaesthesiol | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23820102 |
Spatial variation in automated burst suppression detection in pharmacologically induced coma. | An J, Jonnalagadda D, Moura V, Purdon PL, Brown EN, Westover MB | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 26738009 | Annu Int Conf IEEE Eng Med Biol Soc | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26738009 |
In reply. | Purdon PL, Zhou DW, Akeju O, Brown EN | Anesthesiology | 26284863 | Anesthesiology | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26284863 |
Thalamocortical control of propofol phase-amplitude coupling. | Soplata AE, McCarthy MM, Sherfey J, Lee S, Purdon PL, Brown EN, Kopell N | PLoS computational biology | 29227992 | PLoS Comput Biol | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29227992 |
A study of problems encountered in Granger causality analysis from a neuroscience perspective. | Stokes PA, Purdon PL | Proceedings of the National Academy of Sciences of the United States of America | 28778996 | Proc Natl Acad Sci U S A | 2017 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/28778996 |
Robust time-varying multivariate coherence estimation: application to electroencephalogram recordings during general anesthesia. | Wong KF, Mukamel EA, Salazar AF, Pierce ET, Harrell PG, Walsh JL, Sampson A, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22255393 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22255393 |
STATE-SPACE SOLUTIONS TO THE DYNAMIC MAGNETOENCEPHALOGRAPHY INVERSE PROBLEM USING HIGH PERFORMANCE COMPUTING. | Long CJ, Purdon PL, Temereanca S, Desai NU, Hämäläinen MS, Brown EN | The annals of applied statistics | 22081780 | Ann Appl Stat | 2011 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/22081780 |
Tracking brain states under general anesthesia by using global coherence analysis. | Cimenser A, Purdon PL, Pierce ET, Walsh JL, Salazar-Gomez AF, Harrell PG, Tavares-Stoeckel C, Habeeb K, Brown EN | Proceedings of the National Academy of Sciences of the United States of America | 21555565 | Proc Natl Acad Sci U S A | 2011 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/21555565 |
A transition in brain state during propofol-induced unconsciousness. | Mukamel EA, Pirondini E, Babadi B, Wong KF, Pierce ET, Harrell PG, Walsh JL, Salazar-Gomez AF, Cash SS, Eskandar EN, Weiner VS, Brown EN, Purdon PL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24431442 | J Neurosci | 2014 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/24431442 |
A spatially-regularized dynamic source localization algorithm for EEG. | Pirondini E, Babadi B, Lamus C, Brown EN, Purdon PL | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 23367479 | Annu Int Conf IEEE Eng Med Biol Soc | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23367479 |
Electroencephalogram signatures of loss and recovery of consciousness from propofol. | Purdon PL, Pierce ET, Mukamel EA, Prerau MJ, Walsh JL, Wong KF, Salazar-Gomez AF, Harrell PG, Sampson AL, Cimenser A, Ching S, Kopell NJ, Tavares-Stoeckel C, Habeeb K, Merhar R, Brown EN | Proceedings of the National Academy of Sciences of the United States of America | 23487781 | Proc Natl Acad Sci U S A | 2013 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/23487781 |
Thalamocortical model for a propofol-induced alpha-rhythm associated with loss of consciousness. | Ching S, Cimenser A, Purdon PL, Brown EN, Kopell NJ | Proceedings of the National Academy of Sciences of the United States of America | 21149695 | Proc Natl Acad Sci U S A | 2010 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/21149695 |
A differential autoregressive modeling approach within a point process framework for non-stationary heartbeat intervals analysis. | Chen Z, Purdon PL, Brown EN, Barbieri R | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 21096829 | Annu Int Conf IEEE Eng Med Biol Soc | 2010 | https://www.ncbi.nlm.nih.gov/pubmed/21096829 |
Reference-free harmonic regression technique to remove EEG-fMRI ballistocardiogram artifacts. | Krishnaswamy P, Bonmassar G, Purdon PL, Brown EN | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 24110963 | Annu Int Conf IEEE Eng Med Biol Soc | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24110963 |
A Subspace Pursuit-based Iterative Greedy Hierarchical solution to the neuromagnetic inverse problem. | Babadi B, Obregon-Henao G, Lamus C, Hämäläinen MS, Brown EN, Purdon PL | NeuroImage | 24055554 | Neuroimage | 2014 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/24055554 |
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Functionally diverse dendritic mRNAs rapidly associate with ribosomes following a novel experience. | Ainsley JA, Drane L, Jacobs J, Kittelberger KA, Reijmers LG | Nature communications | 25072471 | Nat Commun | 2014 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/25072471 |
Translational profiling of clock cells reveals circadianly synchronized protein synthesis. | Huang Y, Ainsley JA, Reijmers LG, Jackson FR | PLoS biology | 24348200 | PLoS Biol | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24348200 |
Fear extinction causes target-specific remodeling of perisomatic inhibitory synapses. | Trouche S, Sasaki JM, Tu T, Reijmers LG | Neuron | 24183705 | Neuron | 2013 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/24183705 |
Functional Characterization of the Basal Amygdala-Dorsal BNST Pathway during Contextual Fear Conditioning. | Sasaki Russell J, Trouche S, Reijmers LG | eNeuro | 32601096 | eNeuro | 2020 Jul/Aug | https://www.ncbi.nlm.nih.gov/pubmed/32601096 |
Ribosomal Proteins RPS11 and RPS20, Two Stress-Response Markers of Glioblastoma Stem Cells, Are Novel Predictors of Poor Prognosis in Glioblastoma Patients. | Yong WH, Shabihkhani M, Telesca D, Yang S, Tso JL, Menjivar JC, Wei B, Lucey GM, Mareninov S, Chen Z, Liau LM, Lai A, Nelson SF, Cloughesy TF, Tso CL | PloS one | 26506620 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26506620 |
Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence. | Yamada K, Tso J, Ye F, Choe J, Liu Y, Liau LM, Tso CL | Cancers | 24212792 | Cancers (Basel) | 2011 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/24212792 |
Autocrine endothelin-3/endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells. | Liu Y, Ye F, Yamada K, Tso JL, Zhang Y, Nguyen DH, Dong Q, Soto H, Choe J, Dembo A, Wheeler H, Eskin A, Schmid I, Yong WH, Mischel PS, Cloughesy TF, Kornblum HI, Nelson SF, Liau LM, Tso CL | Molecular cancer research : MCR | 22013079 | Mol Cancer Res | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22013079 |
Protective properties of radio-chemoresistant glioblastoma stem cell clones are associated with metabolic adaptation to reduced glucose dependence. | Ye F, Zhang Y, Liu Y, Yamada K, Tso JL, Menjivar JC, Tian JY, Yong WH, Schaue D, Mischel PS, Cloughesy TF, Nelson SF, Liau LM, McBride W, Tso CL | PloS one | 24260384 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24260384 |
Bone morphogenetic protein 7 sensitizes O6-methylguanine methyltransferase expressing-glioblastoma stem cells to clinically relevant dose of temozolomide. | Tso JL, Yang S, Menjivar JC, Yamada K, Zhang Y, Hong I, Bui Y, Stream A, McBride WH, Liau LM, Nelson SF, Cloughesy TF, Yong WH, Lai A, Tso CL | Molecular cancer | 26546412 | Mol Cancer | 2015 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/26546412 |
Cost-effective and compact wide-field fluorescent imaging on a cell-phone. | Zhu H, Yaglidere O, Su TW, Tseng D, Ozcan A | Lab on a chip | 21063582 | Lab Chip | 2011 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/21063582 |
Killing of targets by CD8 T cells in the mouse spleen follows the law of mass action. | Ganusov VV, Barber DL, De Boer RJ | PloS one | 21283669 | PLoS One | 2011 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/21283669 |
Wide-field lensless fluorescent microscopy using a tapered fiber-optic faceplate on a chip. | Coskun AF, Sencan I, Su TW, Ozcan A | The Analyst | 21283900 | Analyst | 2011 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/21283900 |
Compact and light-weight automated semen analysis platform using lensfree on-chip microscopy. | Su TW, Erlinger A, Tseng D, Ozcan A | Analytical chemistry | 20836503 | Anal Chem | 2010 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/20836503 |
A personalized food allergen testing platform on a cellphone. | Coskun AF, Wong J, Khodadadi D, Nagi R, Tey A, Ozcan A | Lab on a chip | 23254910 | Lab Chip | 2013 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/23254910 |
Lens-free computational imaging of capillary morphogenesis within three-dimensional substrates. | Weidling J, Isikman SO, Greenbaum A, Ozcan A, Botvinick E | Journal of biomedical optics | 23235893 | J Biomed Opt | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23235893 |
Quantum dot enabled detection of Escherichia coli using a cell-phone. | Zhu H, Sikora U, Ozcan A | The Analyst | 22396952 | Analyst | 2012 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/22396952 |
Giga-pixel lensfree holographic microscopy and tomography using color image sensors. | Isikman SO, Greenbaum A, Luo W, Coskun AF, Ozcan A | PloS one | 22984606 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22984606 |
Lensfree microscopy on a cellphone. | Tseng D, Mudanyali O, Oztoprak C, Isikman SO, Sencan I, Yaglidere O, Ozcan A | Lab on a chip | 20445943 | Lab Chip | 2010 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/20445943 |
Holographic pixel super-resolution in portable lensless on-chip microscopy using a fiber-optic array. | Bishara W, Sikora U, Mudanyali O, Su TW, Yaglidere O, Luckhart S, Ozcan A | Lab on a chip | 21365087 | Lab Chip | 2011 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/21365087 |
Combined reflection and transmission microscope for telemedicine applications in field settings. | Biener G, Greenbaum A, Isikman SO, Lee K, Tseng D, Ozcan A | Lab on a chip | 21709875 | Lab Chip | 2011 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/21709875 |
Lensfree fluorescent on-chip imaging of transgenic Caenorhabditis elegans over an ultra-wide field-of-view. | Coskun AF, Sencan I, Su TW, Ozcan A | PloS one | 21253611 | PLoS One | 2011 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/21253611 |
Maskless imaging of dense samples using pixel super-resolution based multi-height lensfree on-chip microscopy. | Greenbaum A, Ozcan A | Optics express | 22330550 | Opt Express | 2012 Jan 30 | https://www.ncbi.nlm.nih.gov/pubmed/22330550 |
Toward giga-pixel nanoscopy on a chip: a computational wide-field look at the nano-scale without the use of lenses. | McLeod E, Luo W, Mudanyali O, Greenbaum A, Ozcan A | Lab on a chip | 23592185 | Lab Chip | 2013 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/23592185 |
Quantification of plant chlorophyll content using Google Glass. | Cortazar B, Koydemir HC, Tseng D, Feng S, Ozcan A | Lab on a chip | 25669673 | Lab Chip | 2015 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/25669673 |
Cellphone-based devices for bioanalytical sciences. | Vashist SK, Mudanyali O, Schneider EM, Zengerle R, Ozcan A | Analytical and bioanalytical chemistry | 24287630 | Anal Bioanal Chem | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24287630 |
Spectral demultiplexing in holographic and fluorescent on-chip microscopy. | Sencan I, Coskun AF, Sikora U, Ozcan A | Scientific reports | 24441627 | Sci Rep | 2014 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/24441627 |
Albumin testing in urine using a smart-phone. | Coskun AF, Nagi R, Sadeghi K, Phillips S, Ozcan A | Lab on a chip | 23995895 | Lab Chip | 2013 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/23995895 |
Giga-pixel fluorescent imaging over an ultra-large field-of-view using a flatbed scanner. | Göröcs Z, Ling Y, Yu MD, Karahalios D, Mogharabi K, Lu K, Wei Q, Ozcan A | Lab on a chip | 24080766 | Lab Chip | 2013 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/24080766 |
On-chip biomedical imaging. | Göröcs Z, Ozcan A | IEEE reviews in biomedical engineering | 23558399 | IEEE Rev Biomed Eng | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23558399 |
Cellphone-based detection platform for rbST biomarker analysis in milk extracts using a microsphere fluorescence immunoassay. | Ludwig SK, Zhu H, Phillips S, Shiledar A, Feng S, Tseng D, van Ginkel LA, Nielen MW, Ozcan A | Analytical and bioanalytical chemistry | 24972876 | Anal Bioanal Chem | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24972876 |
Optical detection and sizing of single nanoparticles using continuous wetting films. | Hennequin Y, Allier CP, McLeod E, Mudanyali O, Migliozzi D, Ozcan A, Dinten JM | ACS nano | 23889001 | ACS Nano | 2013 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/23889001 |
Nanofabrication using near-field optical probes. | McLeod E, Ozcan A | Journal of laboratory automation | 22713756 | J Lab Autom | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22713756 |
Detection of waterborne parasites using field-portable and cost-effective lensfree microscopy. | Mudanyali O, Oztoprak C, Tseng D, Erlinger A, Ozcan A | Lab on a chip | 20694255 | Lab Chip | 2010 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/20694255 |
Lensless wide-field fluorescent imaging on a chip using compressive decoding of sparse objects. | Coskun AF, Sencan I, Su TW, Ozcan A | Optics express | 20588904 | Opt Express | 2010 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/20588904 |
Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution. | Bishara W, Su TW, Coskun AF, Ozcan A | Optics express | 20588977 | Opt Express | 2010 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/20588977 |
Lensfree holographic imaging of antibody microarrays for high-throughput detection of leukocyte numbers and function. | Stybayeva G, Mudanyali O, Seo S, Silangcruz J, Macal M, Ramanculov E, Dandekar S, Erlinger A, Ozcan A, Revzin A | Analytical chemistry | 20359168 | Anal Chem | 2010 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/20359168 |
Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications. | Mudanyali O, Tseng D, Oh C, Isikman SO, Sencan I, Bishara W, Oztoprak C, Seo S, Khademhosseini B, Ozcan A | Lab on a chip | 20401422 | Lab Chip | 2010 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/20401422 |
Optofluidic fluorescent imaging cytometry on a cell phone. | Zhu H, Mavandadi S, Coskun AF, Yaglidere O, Ozcan A | Analytical chemistry | 21774454 | Anal Chem | 2011 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/21774454 |
Wide-field fluorescent microscopy on a cell-phone. | Zhu H, Yaglidere O, Su TW, Tseng D, Ozcan A | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22255900 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22255900 |
Field-portable reflection and transmission microscopy based on lensless holography. | Lee M, Yaglidere O, Ozcan A | Biomedical optics express | 21991559 | Biomed Opt Express | 2011 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/21991559 |
Field-portable lensfree tomographic microscope. | Isikman SO, Bishara W, Sikora U, Yaglidere O, Yeah J, Ozcan A | Lab on a chip | 21573311 | Lab Chip | 2011 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/21573311 |
On-chip differential interference contrast microscopy using lensless digital holography. | Oh C, Isikman SO, Khademhosseinieh B, Ozcan A | Optics express | 20389485 | Opt Express | 2010 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/20389485 |
Lensfree On-Chip Microscopy and Tomography for Bio-Medical Applications. | Isikman SO, Bishara W, Mudanyali O, Sencan I, Su TW, Tseng D, Yaglidere O, Sikora U, Ozcan A | IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society | 24478572 | IEEE J Sel Top Quantum Electron | 2011 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/24478572 |
Wide-field optical detection of nanoparticles using on-chip microscopy and self-assembled nanolenses. | Mudanyali O, McLeod E, Luo W, Greenbaum A, Coskun AF, Hennequin Y, Allier CP, Ozcan A | Nature photonics | 24358054 | Nat Photonics | 2013 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/24358054 |
Holographic opto-fluidic microscopy. | Bishara W, Zhu H, Ozcan A | Optics express | 21197025 | Opt Express | 2010 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/21197025 |
Lensfree on-chip holography facilitates novel microscopy applications. | Ozcan A, Isikman S, Mudanyali O, Tseng D, Sencan I | SPIE newsroom | 21643449 | SPIE Newsroom | 2010 May 19 | https://www.ncbi.nlm.nih.gov/pubmed/21643449 |
Optical imaging techniques for point-of-care diagnostics. | Zhu H, Isikman SO, Mudanyali O, Greenbaum A, Ozcan A | Lab on a chip | 23044793 | Lab Chip | 2013 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/23044793 |
Lensfree optofluidic plasmonic sensor for real-time and label-free monitoring of molecular binding events over a wide field-of-view. | Coskun AF, Cetin AE, Galarreta BC, Alvarez DA, Altug H, Ozcan A | Scientific reports | 25346102 | Sci Rep | 2014 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/25346102 |
Crowd-sourced BioGames: managing the big data problem for next-generation lab-on-a-chip platforms. | Mavandadi S, Dimitrov S, Feng S, Yu F, Yu R, Sikora U, Ozcan A | Lab on a chip | 22918378 | Lab Chip | 2012 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/22918378 |
Optoelectronic tweezers integrated with lensfree holographic microscopy for wide-field interactive cell and particle manipulation on a chip. | Huang KW, Su TW, Ozcan A, Chiou PY | Lab on a chip | 23661233 | Lab Chip | 2013 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/23661233 |
Nano-imaging enabled via self-assembly. | McLeod E, Ozcan A | Nano today | 25506387 | Nano Today | 2014 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/25506387 |
Lensfree super-resolution holographic microscopy using wetting films on a chip. | Mudanyali O, Bishara W, Ozcan A | Optics express | 21935102 | Opt Express | 2011 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/21935102 |
Lensless fluorescent microscopy on a chip. | Coskun AF, Su TW, Sencan I, Ozcan A | Journal of visualized experiments : JoVE | 21876522 | J Vis Exp | 2011 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/21876522 |
Lensfree Fluorescent On-Chip Imaging using Compressive Sampling. | Coskun AF, Su TW, Sencan I, Ozcan A | Optics and photonics news | 21546979 | Opt Photonics News | 2010 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/21546979 |
Lens-free optical tomographic microscope with a large imaging volume on a chip. | Isikman SO, Bishara W, Mavandadi S, Yu FW, Feng S, Lau R, Ozcan A | Proceedings of the National Academy of Sciences of the United States of America | 21504943 | Proc Natl Acad Sci U S A | 2011 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/21504943 |
Biomedical imaging and sensing using flatbed scanners. | Göröcs Z, Ozcan A | Lab on a chip | 24965011 | Lab Chip | 2014 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/24965011 |
Tunable vapor-condensed nanolenses. | McLeod E, Nguyen C, Huang P, Luo W, Veli M, Ozcan A | ACS nano | 24979060 | ACS Nano | 2014 Jul 22 | https://www.ncbi.nlm.nih.gov/pubmed/24979060 |
Immunochromatographic diagnostic test analysis using Google Glass. | Feng S, Caire R, Cortazar B, Turan M, Wong A, Ozcan A | ACS nano | 24571349 | ACS Nano | 2014 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/24571349 |
Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools. | Ozcan A | Lab on a chip | 24647550 | Lab Chip | 2014 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/24647550 |
Color and monochrome lensless on-chip imaging of Caenorhabditis elegans over a wide field-of-view. | Isikman SO, Sencan I, Mudanyali O, Bishara W, Oztoprak C, Ozcan A | Lab on a chip | 20390127 | Lab Chip | 2010 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/20390127 |
Multi-angle lensless digital holography for depth resolved imaging on a chip. | Su TW, Isikman SO, Bishara W, Tseng D, Erlinger A, Ozcan A | Optics express | 20588819 | Opt Express | 2010 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/20588819 |
Fluorescent imaging of single nanoparticles and viruses on a smart phone. | Wei Q, Qi H, Luo W, Tseng D, Ki SJ, Wan Z, Göröcs Z, Bentolila LA, Wu TT, Sun R, Ozcan A | ACS nano | 24016065 | ACS Nano | 2013 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/24016065 |
BioGames: A Platform for Crowd-Sourced Biomedical Image Analysis and Telediagnosis. | Mavandadi S, Feng S, Yu F, Dimitrov S, Yu R, Ozcan A | Games for health journal | 23724363 | Games Health J | 2012 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/23724363 |
Wide-field computational color imaging using pixel super-resolved on-chip microscopy. | Greenbaum A, Feizi A, Akbari N, Ozcan A | Optics express | 23736466 | Opt Express | 2013 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/23736466 |
High-throughput lens-free blood analysis on a chip. | Seo S, Isikman SO, Sencan I, Mudanyali O, Su TW, Bishara W, Erlinger A, Ozcan A | Analytical chemistry | 20450181 | Anal Chem | 2010 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/20450181 |
High-throughput screening of large volumes of whole blood using structured illumination and fluorescent on-chip imaging. | Arpali SA, Arpali C, Coskun AF, Chiang HH, Ozcan A | Lab on a chip | 23047492 | Lab Chip | 2012 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/23047492 |
High-throughput lensfree 3D tracking of human sperms reveals rare statistics of helical trajectories. | Su TW, Xue L, Ozcan A | Proceedings of the National Academy of Sciences of the United States of America | 22988076 | Proc Natl Acad Sci U S A | 2012 Oct 2 | https://www.ncbi.nlm.nih.gov/pubmed/22988076 |
Partially coherent lensfree tomographic microscopy [Invited]. | Isikman SO, Bishara W, Ozcan A | Applied optics | 22193016 | Appl Opt | 2011 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/22193016 |
Lensless fluorescent on-chip microscopy using a fiber-optic taper. | Coskun AF, Sencan I, Su TW, Ozcan A | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22255702 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22255702 |
Portable and cost-effective pixel super-resolution on-chip microscope for telemedicine applications. | Bishara W, Sikora U, Mudanyali O, Su TW, Yaglidere O, Luckhart S, Ozcan A | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22256247 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22256247 |
Integrated rapid-diagnostic-test reader platform on a cellphone. | Mudanyali O, Dimitrov S, Sikora U, Padmanabhan S, Navruz I, Ozcan A | Lab on a chip | 22596243 | Lab Chip | 2012 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/22596243 |
Lensfree computational microscopy tools for cell and tissue imaging at the point-of-care and in low-resource settings. | Isikman SO, Greenbaum A, Lee M, Bishara W, Mudanyali O, Su TW, Ozcan A | Analytical cellular pathology (Amsterdam) | 22433451 | Anal Cell Pathol (Amst) | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22433451 |
Wide-field fluorescent microscopy and fluorescent imaging flow cytometry on a cell-phone. | Zhu H, Ozcan A | Journal of visualized experiments : JoVE | 23603893 | J Vis Exp | 2013 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/23603893 |
On-chip cytometry using plasmonic nanoparticle enhanced lensfree holography. | Wei Q, McLeod E, Qi H, Wan Z, Sun R, Ozcan A | Scientific reports | 23608952 | Sci Rep | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23608952 |
Flexible Plasmonic Sensors. | Shir D, Ballard ZS, Ozcan A | IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society | 27547023 | IEEE J Sel Top Quantum Electron | 2016 Jul-Aug | https://www.ncbi.nlm.nih.gov/pubmed/27547023 |
Democratization of Nanoscale Imaging and Sensing Tools Using Photonics. | McLeod E, Wei Q, Ozcan A | Analytical chemistry | 26068279 | Anal Chem | 2015 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/26068279 |
Sperm trajectories form chiral ribbons. | Su TW, Choi I, Feng J, Huang K, McLeod E, Ozcan A | Scientific reports | 23588811 | Sci Rep | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23588811 |
Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array. | Navruz I, Coskun AF, Wong J, Mohammad S, Tseng D, Nagi R, Phillips S, Ozcan A | Lab on a chip | 23939637 | Lab Chip | 2013 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/23939637 |
Field-portable pixel super-resolution colour microscope. | Greenbaum A, Akbari N, Feizi A, Luo W, Ozcan A | PloS one | 24086742 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24086742 |
Automated single-cell motility analysis on a chip using lensfree microscopy. | Pushkarsky I, Liu Y, Weaver W, Su TW, Mudanyali O, Ozcan A, Di Carlo D | Scientific reports | 24739819 | Sci Rep | 2014 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/24739819 |
Detection and spatial mapping of mercury contamination in water samples using a smart-phone. | Wei Q, Nagi R, Sadeghi K, Feng S, Yan E, Ki SJ, Caire R, Tseng D, Ozcan A | ACS nano | 24437470 | ACS Nano | 2014 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/24437470 |
Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy. | Greenbaum A, Luo W, Su TW, Göröcs Z, Xue L, Isikman SO, Coskun AF, Mudanyali O, Ozcan A | Nature methods | 22936170 | Nat Methods | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22936170 |
A mathematical framework for combining decisions of multiple experts toward accurate and remote diagnosis of malaria using tele-microscopy. | Mavandadi S, Feng S, Yu F, Dimitrov S, Nielsen-Saines K, Prescott WR, Ozcan A | PloS one | 23071544 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23071544 |
Cost-effective and rapid blood analysis on a cell-phone. | Zhu H, Sencan I, Wong J, Dimitrov S, Tseng D, Nagashima K, Ozcan A | Lab on a chip | 23392286 | Lab Chip | 2013 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/23392286 |
Computational imaging, sensing and diagnostics for global health applications. | Coskun AF, Ozcan A | Current opinion in biotechnology | 24484875 | Curr Opin Biotechnol | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24484875 |
Wide field-of-view lens-free fluorescent imaging on a chip. | Coskun AF, Su TW, Ozcan A | Lab on a chip | 20379564 | Lab Chip | 2010 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/20379564 |
Smart technology for global access to healthcare. | Ozcan A | SPIE newsroom | 20582244 | SPIE Newsroom | 2010 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/20582244 |
Optofluidic on-chip tomography. | Isikman SO, Bishara W, Zhu H, Ozcan A | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 22256312 | Annu Int Conf IEEE Eng Med Biol Soc | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22256312 |
Optofluidic Tomography on a Chip. | Isikman SO, Bishara W, Zhu H, Ozcan A | Applied physics letters | 21580801 | Appl Phys Lett | 2011 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/21580801 |
Analysis of Diffractive Optical Neural Networks and Their Integration with Electronic Neural Networks. | Mengu D, Luo Y, Rivenson Y, Ozcan A | IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society | 33223801 | IEEE J Sel Top Quantum Electron | 2020 Jan-Feb | https://www.ncbi.nlm.nih.gov/pubmed/33223801 |
High-throughput and label-free single nanoparticle sizing based on time-resolved on-chip microscopy. | McLeod E, Dincer TU, Veli M, Ertas YN, Nguyen C, Luo W, Greenbaum A, Feizi A, Ozcan A | ACS nano | 25688665 | ACS Nano | 2015 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/25688665 |
Promoters recognized by forkhead proteins exist for individual 21U-RNAs. | Cecere G, Zheng GX, Mansisidor AR, Klymko KE, Grishok A | Molecular cell | 22819322 | Mol Cell | 2012 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/22819322 |
Endogenous RNAi and adaptation to environment in C. elegans. | Grishok A | Worm | 24058837 | Worm | 2012 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24058837 |
CSR-1 RNAi pathway positively regulates histone expression in C. elegans. | Avgousti DC, Palani S, Sherman Y, Grishok A | The EMBO journal | 22863779 | EMBO J | 2012 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/22863779 |
A nuclear perspective on RNAi pathways in metazoans. | Cecere G, Grishok A | Biochimica et biophysica acta | 24361586 | Biochim Biophys Acta | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24361586 |
The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcription. | Cecere G, Hoersch S, Jensen MB, Dixit S, Grishok A | Molecular cell | 23806335 | Mol Cell | 2013 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/23806335 |
Development and interlaboratory validation of a QuEChERS-based liquid chromatography-tandem mass spectrometry method for multiresidue pesticide analysis. | Wong J, Hao C, Zhang K, Yang P, Banerjee K, Hayward D, Iftakhar I, Schreiber A, Tech K, Sack C, Smoker M, Chen X, Utture SC, Oulkar DP | Journal of agricultural and food chemistry | 20196606 | J Agric Food Chem | 2010 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/20196606 |
Organohalogen and organophosphorous pesticide method for ginseng root--a comparison of gas chromatography-single quadrupole mass spectrometry with high resolution time-of-flight mass spectrometry. | Hayward DG, Wong JW | Analytical chemistry | 19548696 | Anal Chem | 2009 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/19548696 |
A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in Caenorhabditis elegans. | Mansisidor AR, Cecere G, Hoersch S, Jensen MB, Kawli T, Kennedy LM, Chavez V, Tan MW, Lieb JD, Grishok A | PLoS genetics | 21980302 | PLoS Genet | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21980302 |
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Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity. | Xiang Z, Ren H, Hu YS, Coin I, Wei J, Cang H, Wang L | Nature methods | 23913257 | Nat Methods | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23913257 |
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Genetically encoding unnatural amino acids in neural stem cells and optically reporting voltage-sensitive domain changes in differentiated neurons. | Shen B, Xiang Z, Miller B, Louie G, Wang W, Noel JP, Gage FH, Wang L | Stem cells (Dayton, Ohio) | 21681861 | Stem Cells | 2011 Aug | https://www.ncbi.nlm.nih.gov/pubmed/21681861 |
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Expanding the library and substrate diversity of the pyrrolysyl-tRNA synthetase to incorporate unnatural amino acids containing conjugated rings. | Lacey VK, Louie GV, Noel JP, Wang L | Chembiochem : a European journal of chemical biology | 24019075 | Chembiochem | 2013 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/24019075 |
Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR. | Coin I, Katritch V, Sun T, Xiang Z, Siu FY, Beyermann M, Stevens RC, Wang L | Cell | 24290358 | Cell | 2013 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/24290358 |
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A fluorescent reporter of the phosphorylation status of the substrate protein STAT3. | Lacey VK, Parrish AR, Han S, Shen Z, Briggs SP, Ma Y, Wang L | Angewandte Chemie (International ed. in English) | 21805546 | Angew Chem Int Ed Engl | 2011 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/21805546 |
Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA pairs. | Parrish AR, She X, Xiang Z, Coin I, Shen Z, Briggs SP, Dillin A, Wang L | ACS chemical biology | 22554080 | ACS Chem Biol | 2012 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/22554080 |
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Advances in lectin microarray technology: optimized protocols for piezoelectric print conditions. | Pilobello KT, Agrawal P, Rouse R, Mahal LK | Current protocols in chemical biology | 23788322 | Curr Protoc Chem Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23788322 |
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Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode. | Agrawal P, Kurcon T, Pilobello KT, Rakus JF, Koppolu S, Liu Z, Batista BS, Eng WS, Hsu KL, Liang Y, Mahal LK | Proceedings of the National Academy of Sciences of the United States of America | 24591635 | Proc Natl Acad Sci U S A | 2014 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/24591635 |
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Insights into miRNA regulation of the human glycome. | Kasper BT, Koppolu S, Mahal LK | Biochemical and biophysical research communications | 24463102 | Biochem Biophys Res Commun | 2014 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/24463102 |
Identification of a conserved glycan signature for microvesicles. | Batista BS, Eng WS, Pilobello KT, Hendricks-Muñoz KD, Mahal LK | Journal of proteome research | 21859146 | J Proteome Res | 2011 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/21859146 |
Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. | Liang Y, Eng WS, Colquhoun DR, Dinglasan RR, Graham DR, Mahal LK | The Journal of biological chemistry | 25261472 | J Biol Chem | 2014 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/25261472 |
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Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. | Koh FM, Lizama CO, Wong P, Hawkins JS, Zovein AC, Ramalho-Santos M | Proceedings of the National Academy of Sciences of the United States of America | 25831528 | Proc Natl Acad Sci U S A | 2015 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/25831528 |
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Bivalent chromatin marks developmental regulatory genes in the mouse embryonic germline in vivo. | Sachs M, Onodera C, Blaschke K, Ebata KT, Song JS, Ramalho-Santos M | Cell reports | 23727241 | Cell Rep | 2013 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/23727241 |
Histone variant H3.3 maintains a decondensed chromatin state essential for mouse preimplantation development. | Lin CJ, Conti M, Ramalho-Santos M | Development (Cambridge, England) | 23903189 | Development | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23903189 |
Systematic identification of barriers to human iPSC generation. | Qin H, Diaz A, Blouin L, Lebbink RJ, Patena W, Tanbun P, LeProust EM, McManus MT, Song JS, Ramalho-Santos M | Cell | 25036638 | Cell | 2014 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/25036638 |
Hira-mediated H3.3 incorporation is required for DNA replication and ribosomal RNA transcription in the mouse zygote. | Lin CJ, Koh FM, Wong P, Conti M, Ramalho-Santos M | Developmental cell | 25087892 | Dev Cell | 2014 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/25087892 |
Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast. | Guzman-Ayala M, Sachs M, Koh FM, Onodera C, Bulut-Karslioglu A, Lin CJ, Wong P, Nitta R, Song JS, Ramalho-Santos M | Development (Cambridge, England) | 25480920 | Development | 2015 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/25480920 |
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Recent developments in single-molecule DNA mechanics. | Bryant Z, Oberstrass FC, Basu A | Current opinion in structural biology | 22658779 | Curr Opin Struct Biol | 2012 Jun | https://www.ncbi.nlm.nih.gov/pubmed/22658779 |
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ATP binding controls distinct structural transitions of Escherichia coli DNA gyrase in complex with DNA. | Basu A, Schoeffler AJ, Berger JM, Bryant Z | Nature structural & molecular biology | 22484318 | Nat Struct Mol Biol | 2012 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/22484318 |
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Remote control of myosin and kinesin motors using light-activated gearshifting. | Nakamura M, Chen L, Howes SC, Schindler TD, Nogales E, Bryant Z | Nature nanotechnology | 25086603 | Nat Nanotechnol | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25086603 |
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Processive ATP-driven substrate disassembly by the N-ethylmaleimide-sensitive factor (NSF) molecular machine. | Cipriano DJ, Jung J, Vivona S, Fenn TD, Brunger AT, Bryant Z | The Journal of biological chemistry | 23775070 | J Biol Chem | 2013 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/23775070 |
Engineering myosins for long-range transport on actin filaments. | Schindler TD, Chen L, Lebel P, Nakamura M, Bryant Z | Nature nanotechnology | 24240432 | Nat Nanotechnol | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24240432 |
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Torque spectroscopy of DNA: base-pair stability, boundary effects, backbending, and breathing dynamics. | Oberstrass FC, Fernandes LE, Lebel P, Bryant Z | Physical review letters | 23679785 | Phys Rev Lett | 2013 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/23679785 |
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Mechanism of fatty-acid-dependent UCP1 uncoupling in brown fat mitochondria. | Fedorenko A, Lishko PV, Kirichok Y | Cell | 23063128 | Cell | 2012 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/23063128 |
Folding DNA origami from a double-stranded source of scaffold. | Högberg B, Liedl T, Shih WM | Journal of the American Chemical Society | 19566089 | J Am Chem Soc | 2009 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/19566089 |
Recovery of intact DNA nanostructures after agarose gel-based separation. | Bellot G, McClintock MA, Lin C, Shih WM | Nature methods | 21358621 | Nat Methods | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21358621 |
Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching. | Berardi MJ, Shih WM, Harrison SC, Chou JJ | Nature | 21785437 | Nature | 2011 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/21785437 |
Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape. | Bastings MMC, Anastassacos FM, Ponnuswamy N, Leifer FG, Cuneo G, Lin C, Ingber DE, Ryu JH, Shih WM | Nano letters | 29756442 | Nano Lett | 2018 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/29756442 |
Disruption of helix-capping residues 671 and 674 reveals a role in HIV-1 entry for a specialized hinge segment of the membrane proximal external region of gp41. | Sun ZY, Cheng Y, Kim M, Song L, Choi J, Kudahl UJ, Brusic V, Chowdhury B, Yu L, Seaman MS, Bellot G, Shih WM, Wagner G, Reinherz EL | Journal of molecular biology | 24075869 | J Mol Biol | 2014 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/24075869 |
Multilayer DNA origami packed on hexagonal and hybrid lattices. | Ke Y, Voigt NV, Gothelf KV, Shih WM | Journal of the American Chemical Society | 22187940 | J Am Chem Soc | 2012 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/22187940 |
DNA origami structures directly assembled from intact bacteriophages. | Nickels PC, Ke Y, Jungmann R, Smith DM, Leichsenring M, Shih WM, Liedl T, Högberg B | Small (Weinheim an der Bergstrasse, Germany) | 24532395 | Small | 2014 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/24532395 |
Two design strategies for enhancement of multilayer-DNA-origami folding: underwinding for specific intercalator rescue and staple-break positioning. | Ke Y, Bellot G, Voigt NV, Fradkov E, Shih WM | Chemical science | 24653832 | Chem Sci | 2012 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/24653832 |
Purification of DNA-origami nanostructures by rate-zonal centrifugation. | Lin C, Perrault SD, Kwak M, Graf F, Shih WM | Nucleic acids research | 23155067 | Nucleic Acids Res | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23155067 |
Regulation at a distance of biomolecular interactions using a DNA origami nanoactuator. | Ke Y, Meyer T, Shih WM, Bellot G | Nature communications | 26988942 | Nat Commun | 2016 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/26988942 |
Virus-inspired membrane encapsulation of DNA nanostructures to achieve in vivo stability. | Perrault SD, Shih WM | ACS nano | 24694301 | ACS Nano | 2014 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/24694301 |
Self-assembly of DNA into nanoscale three-dimensional shapes. | Douglas SM, Dietz H, Liedl T, Högberg B, Graf F, Shih WM | Nature | 19458720 | Nature | 2009 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/19458720 |
Enzymatic production of 'monoclonal stoichiometric' single-stranded DNA oligonucleotides. | Ducani C, Kaul C, Moche M, Shih WM, Högberg B | Nature methods | 23727986 | Nat Methods | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23727986 |
Designing DNA Nanotube Liquid Crystals as a Weak-Alignment Medium for NMR Structure Determination of Membrane Proteins. | Min J, Shih WM, Bellot G | Methods in molecular biology (Clifton, N.J.) | 27813010 | Methods Mol Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/27813010 |
Knitting complex weaves with DNA origami. | Shih WM, Lin C | Current opinion in structural biology | 20456942 | Curr Opin Struct Biol | 2010 Jun | https://www.ncbi.nlm.nih.gov/pubmed/20456942 |
Rapid prototyping of 3D DNA-origami shapes with caDNAno. | Douglas SM, Marblestone AH, Teerapittayanon S, Vazquez A, Church GM, Shih WM | Nucleic acids research | 19531737 | Nucleic Acids Res | 2009 Aug | https://www.ncbi.nlm.nih.gov/pubmed/19531737 |
Multilayer DNA origami packed on a square lattice. | Ke Y, Douglas SM, Liu M, Sharma J, Cheng A, Leung A, Liu Y, Shih WM, Yan H | Journal of the American Chemical Society | 19807088 | J Am Chem Soc | 2009 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/19807088 |
A Programmable DNA Origami Platform to Organize SNAREs for Membrane Fusion. | Xu W, Nathwani B, Lin C, Wang J, Karatekin E, Pincet F, Shih W, Rothman JE | Journal of the American Chemical Society | 26938705 | J Am Chem Soc | 2016 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/26938705 |
Tug-of-war in motor protein ensembles revealed with a programmable DNA origami scaffold. | Derr ND, Goodman BS, Jungmann R, Leschziner AE, Shih WM, Reck-Peterson SL | Science (New York, N.Y.) | 23065903 | Science | 2012 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/23065903 |
Scalable amplification of strand subsets from chip-synthesized oligonucleotide libraries. | Schmidt TL, Beliveau BJ, Uca YO, Theilmann M, Da Cruz F, Wu CT, Shih WM | Nature communications | 26567534 | Nat Commun | 2015 Nov 16 | https://www.ncbi.nlm.nih.gov/pubmed/26567534 |
Self-assembly of size-controlled liposomes on DNA nanotemplates. | Yang Y, Wang J, Shigematsu H, Xu W, Shih WM, Rothman JE, Lin C | Nature chemistry | 27102682 | Nat Chem | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27102682 |
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Self-assembly of three-dimensional prestressed tensegrity structures from DNA. | Liedl T, Högberg B, Tytell J, Ingber DE, Shih WM | Nature nanotechnology | 20562873 | Nat Nanotechnol | 2010 Jul | https://www.ncbi.nlm.nih.gov/pubmed/20562873 |
Programming Self-Assembly of DNA Origami Honeycomb Two-Dimensional Lattices and Plasmonic Metamaterials. | Wang P, Gaitanaros S, Lee S, Bathe M, Shih WM, Ke Y | Journal of the American Chemical Society | 27224641 | J Am Chem Soc | 2016 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/27224641 |
Structural determinants of PERK inhibitor potency and selectivity. | Wang H, Blais J, Ron D, Cardozo T | Chemical biology & drug design | 21070610 | Chem Biol Drug Des | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21070610 |
Triazolo[4,5-d]pyrimidines as Validated General Control Nonderepressible 2 (GCN2) Protein Kinase Inhibitors Reduce Growth of Leukemia Cells. | Lough L, Sherman D, Beccera-Flores M, Lavinda O, Ni E, Wang H, Tibes R, Cardozo T | Computational and structural biotechnology journal | 30364637 | Comput Struct Biotechnol J | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30364637 |
Can the energy gap in the protein-ligand binding energy landscape be used as a descriptor in virtual ligand screening? | Grigoryan AV, Wang H, Cardozo TJ | PloS one | 23071584 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23071584 |
Visualizing the phage T4 activated transcription complex of DNA and E. coli RNA polymerase. | James TD, Cardozo T, Abell LE, Hsieh ML, Jenkins LM, Jha SS, Hinton DM | Nucleic acids research | 27458207 | Nucleic Acids Res | 2016 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/27458207 |
Statins Increase Plasminogen Activator Inhibitor Type 1 Gene Transcription through a Pregnane X Receptor Regulated Element. | Stanley FM, Linder KM, Cardozo TJ | PloS one | 26379245 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26379245 |
Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer. | Pavlides SC, Huang KT, Reid DA, Wu L, Blank SV, Mittal K, Guo L, Rothenberg E, Rueda B, Cardozo T, Gold LI | Endocrinology | 24035998 | Endocrinology | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24035998 |
Structural Model of the Extracellular Assembly of the TCR-CD3 Complex. | Natarajan A, Nadarajah V, Felsovalyi K, Wang W, Jeyachandran VR, Wasson RA, Cardozo T, Bracken C, Krogsgaard M | Cell reports | 26997265 | Cell Rep | 2016 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/26997265 |
Tagetitoxin inhibits RNA polymerase through trapping of the trigger loop. | Artsimovitch I, Svetlov V, Nemetski SM, Epshtein V, Cardozo T, Nudler E | The Journal of biological chemistry | 21976682 | J Biol Chem | 2011 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/21976682 |
Indirect detection of an epitope-specific response to HIV-1 gp120 immunization in human subjects. | Shmelkov E, Nadas A, Swetnam J, Zolla-Pazner S, Cardozo T | PloS one | 22076145 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22076145 |
Assessment of immunologically relevant dynamic tertiary structural features of the HIV-1 V3 loop crown R2 sequence by ab initio folding. | Almond D, Cardozo T | Journal of visualized experiments : JoVE | 20864931 | J Vis Exp | 2010 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/20864931 |
Worldwide distribution of HIV type 1 epitopes recognized by human anti-V3 monoclonal antibodies. | Cardozo T, Swetnam J, Pinter A, Krachmarov C, Nadas A, Almond D, Zolla-Pazner S | AIDS research and human retroviruses | 19320565 | AIDS Res Hum Retroviruses | 2009 Apr | https://www.ncbi.nlm.nih.gov/pubmed/19320565 |
An Improved Method for Modeling Voltage-Gated Ion Channels at Atomic Accuracy Applied to Human Ca(v) Channels. | Martinez-Ortiz W, Cardozo TJ | Cell reports | 29719253 | Cell Rep | 2018 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/29719253 |
Ro52 autoantibodies arise from self-reactive progenitors in a mother of a child with neonatal lupus. | Reed JH, Gorny MK, Li L, Cardozo T, Buyon JP, Clancy RM | Journal of autoimmunity | 28118945 | J Autoimmun | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28118945 |
Recombinant derivatives of botulinum neurotoxin A engineered for trafficking studies and neuronal delivery. | Band PA, Blais S, Neubert TA, Cardozo TJ, Ichtchenko K | Protein expression and purification | 20045734 | Protein Expr Purif | 2010 May | https://www.ncbi.nlm.nih.gov/pubmed/20045734 |
Vaccine focusing to cross-subtype HIV-1 gp120 variable loop epitopes. | Cardozo T, Wang S, Jiang X, Kong XP, Hioe C, Krachmarov C | Vaccine | 25045827 | Vaccine | 2014 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/25045827 |
Specific small molecule inhibitors of Skp2-mediated p27 degradation. | Wu L, Grigoryan AV, Li Y, Hao B, Pagano M, Cardozo TJ | Chemistry & biology | 23261596 | Chem Biol | 2012 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/23261596 |
Specific increase in potency via structure-based design of a TCR. | Malecek K, Grigoryan A, Zhong S, Gu WJ, Johnson LA, Rosenberg SA, Cardozo T, Krogsgaard M | Journal of immunology (Baltimore, Md. : 1950) | 25070852 | J Immunol | 2014 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/25070852 |
Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations. | Martin L, Grigoryan A, Wang D, Wang J, Breda L, Rivella S, Cardozo T, Gardner LB | Cancer research | 24662918 | Cancer Res | 2014 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/24662918 |
Quantitative assessment of masking of neutralization epitopes in HIV-1. | Agarwal A, Hioe CE, Swetnam J, Zolla-Pazner S, Cardozo T | Vaccine | 21216319 | Vaccine | 2011 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/21216319 |
Nuclear receptor engineering based on novel structure activity relationships revealed by farnesyl pyrophosphate. | Goyanka R, Das S, Samuels HH, Cardozo T | Protein engineering, design & selection : PEDS | 20817759 | Protein Eng Des Sel | 2010 Nov | https://www.ncbi.nlm.nih.gov/pubmed/20817759 |
Modulation of Macrophage Gene Expression via Liver X Receptor α Serine 198 Phosphorylation. | Wu C, Hussein MA, Shrestha E, Leone S, Aiyegbo MS, Lambert WM, Pourcet B, Cardozo T, Gustafson JA, Fisher EA, Pineda-Torra I, Garabedian MJ | Molecular and cellular biology | 25825525 | Mol Cell Biol | 2015 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/25825525 |
Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex. | Nemetski SM, Cardozo TJ, Bosch G, Weltzer R, O'Malley K, Ejigiri I, Kumar KA, Buscaglia CA, Nussenzweig V, Sinnis P, Levitskaya J, Bosch J | Malaria journal | 26289816 | Malar J | 2015 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/26289816 |
Translational induction of ATF4 during integrated stress response requires noncanonical initiation factors eIF2D and DENR. | Vasudevan D, Neuman SD, Yang A, Lough L, Brown B, Bashirullah A, Cardozo T, Ryoo HD | Nature communications | 32938929 | Nat Commun | 2020 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/32938929 |
HIV's Nef interacts with β-catenin of the Wnt signaling pathway in HEK293 cells. | Weiser K, Barton M, Gershoony D, Dasgupta R, Cardozo T | PloS one | 24130899 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24130899 |
Quantitative analysis of T cell receptor complex interaction sites using genetically encoded photo-cross-linkers. | Wang W, Li T, Felsovalyi K, Chen C, Cardozo T, Krogsgaard M | ACS chemical biology | 25061810 | ACS Chem Biol | 2014 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/25061810 |
Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite. | Bosch J, Buscaglia CA, Krumm B, Ingason BP, Lucas R, Roach C, Cardozo T, Nussenzweig V, Hol WG | Proceedings of the National Academy of Sciences of the United States of America | 17426153 | Proc Natl Acad Sci U S A | 2007 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/17426153 |
Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes. | Cardozo T, Pagano M | BMC biochemistry | 18047746 | BMC Biochem | 2007 Nov 22 | https://www.ncbi.nlm.nih.gov/pubmed/18047746 |
The architecture of CopA from Archeaoglobus fulgidus studied by cryo-electron microscopy and computational docking. | Allen GS, Wu CC, Cardozo T, Stokes DL | Structure (London, England : 1993) | 21820315 | Structure | 2011 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/21820315 |
Assessing quality and completeness of human transcriptional regulatory pathways on a genome-wide scale. | Shmelkov E, Tang Z, Aifantis I, Statnikov A | Biology direct | 21356087 | Biol Direct | 2011 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/21356087 |
Structure-function relationships of HIV-1 envelope sequence-variable regions refocus vaccine design. | Zolla-Pazner S, Cardozo T | Nature reviews. Immunology | 20577269 | Nat Rev Immunol | 2010 Jul | https://www.ncbi.nlm.nih.gov/pubmed/20577269 |
Resistance of Subtype C HIV-1 Strains to Anti-V3 Loop Antibodies. | Almond D, Krachmarov C, Swetnam J, Zolla-Pazner S, Cardozo T | Advances in virology | 22548061 | Adv Virol | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22548061 |
Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation. | Sun Y, Nien CY, Chen K, Liu HY, Johnston J, Zeitlinger J, Rushlow C | Genome research | 26335633 | Genome Res | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26335633 |
TRF2, but not TBP, mediates the transcription of ribosomal protein genes. | Wang YL, Duttke SH, Chen K, Johnston J, Kassavetis GA, Zeitlinger J, Kadonaga JT | Genes & development | 24958592 | Genes Dev | 2014 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/24958592 |
TATA and paused promoters active in differentiated tissues have distinct expression characteristics. | Ramalingam V, Natarajan M, Johnston J, Zeitlinger J | Molecular systems biology | 33543829 | Mol Syst Biol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33543829 |
ChIP-nexus enables improved detection of in vivo transcription factor binding footprints. | He Q, Johnston J, Zeitlinger J | Nature biotechnology | 25751057 | Nat Biotechnol | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25751057 |
A global change in RNA polymerase II pausing during the Drosophila midblastula transition. | Chen K, Johnston J, Shao W, Meier S, Staber C, Zeitlinger J | eLife | 23951546 | Elife | 2013 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/23951546 |
Hippo Reprograms the Transcriptional Response to Ras Signaling. | Pascual J, Jacobs J, Sansores-Garcia L, Natarajan M, Zeitlinger J, Aerts S, Halder G, Hamaratoglu F | Developmental cell | 28950103 | Dev Cell | 2017 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/28950103 |
Identification of transcription factor binding sites from ChIP-seq data at high resolution. | Bardet AF, Steinmann J, Bafna S, Knoblich JA, Zeitlinger J, Stark A | Bioinformatics (Oxford, England) | 23980024 | Bioinformatics | 2013 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/23980024 |
Poised RNA polymerase II changes over developmental time and prepares genes for future expression. | Gaertner B, Johnston J, Chen K, Wallaschek N, Paulson A, Garruss AS, Gaudenz K, De Kumar B, Krumlauf R, Zeitlinger J | Cell reports | 23260668 | Cell Rep | 2012 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/23260668 |
Drosophila poised enhancers are generated during tissue patterning with the help of repression. | Koenecke N, Johnston J, He Q, Meier S, Zeitlinger J | Genome research | 27979994 | Genome Res | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27979994 |
Lola-I is a promoter pioneer factor that establishes de novo Pol II pausing during development. | Ramalingam V, Yu X, Slaughter BD, Unruh JR, Brennan KJ, Onyshchenko A, Lange JJ, Natarajan M, Buck M, Zeitlinger J | Nature communications | 37735176 | Nat Commun | 2023 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/37735176 |
One size may not fit all: anti-aging therapies and sarcopenia. | Burks TN, Cohn RD | Aging | 22184279 | Aging (Albany NY) | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22184279 |
Maintaining skeletal muscle mass: lessons learned from hibernation. | Ivakine EA, Cohn RD | Experimental physiology | 24443348 | Exp Physiol | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24443348 |
Regulation of muscle mass by follistatin and activins. | Lee SJ, Lee YS, Zimmers TA, Soleimani A, Matzuk MM, Tsuchida K, Cohn RD, Barton ER | Molecular endocrinology (Baltimore, Md.) | 20810712 | Mol Endocrinol | 2010 Oct | https://www.ncbi.nlm.nih.gov/pubmed/20810712 |
TGFβ signaling: its role in fibrosis formation and myopathies. | MacDonald EM, Cohn RD | Current opinion in rheumatology | 22918531 | Curr Opin Rheumatol | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/22918531 |
Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels. | Andres-Mateos E, Mejias R, Soleimani A, Lin BM, Burks TN, Marx R, Lin B, Zellars RC, Zhang Y, Huso DL, Marr TG, Leinwand LA, Merriman DK, Cohn RD | PloS one | 23155423 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23155423 |
Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy. | Andres-Mateos E, Brinkmeier H, Burks TN, Mejias R, Files DC, Steinberger M, Soleimani A, Marx R, Simmers JL, Lin B, Finanger Hedderick E, Marr TG, Lin BM, Hourdé C, Leinwand LA, Kuhl D, Föller M, Vogelsang S, Hernandez-Diaz I, Vaughan DK, Alvarez de la Rosa D, Lang F, Cohn RD | EMBO molecular medicine | 23161797 | EMBO Mol Med | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23161797 |
Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization. | Xu R, Andres-Mateos E, Mejias R, MacDonald EM, Leinwand LA, Merriman DK, Fink RH, Cohn RD | Experimental neurology | 23333568 | Exp Neurol | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23333568 |
Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibition. | MacDonald EM, Andres-Mateos E, Mejias R, Simmers JL, Mi R, Park JS, Ying S, Hoke A, Lee SJ, Cohn RD | Disease models & mechanisms | 24504412 | Dis Model Mech | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24504412 |
Loss of sarcolemmal nNOS is common in acquired and inherited neuromuscular disorders. | Finanger Hedderick EL, Simmers JL, Soleimani A, Andres-Mateos E, Marx R, Files DC, King L, Crawford TO, Corse AM, Cohn RD | Neurology | 21403107 | Neurology | 2011 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/21403107 |
Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. | Burks TN, Andres-Mateos E, Marx R, Mejias R, Van Erp C, Simmers JL, Walston JD, Ward CW, Cohn RD | Science translational medicine | 21562229 | Sci Transl Med | 2011 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/21562229 |
Gle1 functions during mRNA export in an oligomeric complex that is altered in human disease. | Folkmann AW, Collier SE, Zhan X, Aditi, Ohi MD, Wente SR | Cell | 24243016 | Cell | 2013 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/24243016 |
Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. | Livesay SB, Collier SE, Bitton DA, Bähler J, Ohi MD | Eukaryotic cell | 24014766 | Eukaryot Cell | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24014766 |
The Prp19 WD40 domain contains a conserved protein interaction region essential for its function. | Vander Kooi CW, Ren L, Xu P, Ohi MD, Gould KL, Chazin WJ | Structure (London, England : 1993) | 20462492 | Structure | 2010 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/20462492 |
Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation. | Chen JS, Lu LX, Ohi MD, Creamer KM, English C, Partridge JF, Ohi R, Gould KL | The Journal of cell biology | 22065639 | J Cell Biol | 2011 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/22065639 |
Structural and functional insights into the N-terminus of Schizosaccharomyces pombe Cdc5. | Collier SE, Voehler M, Peng D, Ohi R, Gould KL, Reiter NJ, Ohi MD | Biochemistry | 25263959 | Biochemistry | 2014 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/25263959 |
Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. | Ren L, McLean JR, Hazbun TR, Fields S, Vander Kooi C, Ohi MD, Gould KL | PloS one | 21386897 | PLoS One | 2011 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/21386897 |
Tailoring of membrane proteins by alternative splicing of pre-mRNA. | Mittendorf KF, Deatherage CL, Ohi MD, Sanders CR | Biochemistry | 22708632 | Biochemistry | 2012 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/22708632 |
Glycolytic enzymes localize to ribonucleoprotein granules in Drosophila germ cells, bind Tudor and protect from transposable elements. | Gao M, Thomson TC, Creed TM, Tu S, Loganathan SN, Jackson CA, McCluskey P, Lin Y, Collier SE, Weng Z, Lasko P, Ohi MD, Arkov AL | EMBO reports | 25600116 | EMBO Rep | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25600116 |
Cysteine proteinase-1 and cut protein isoform control dendritic innervation of two distinct sensory fields by a single neuron. | Lyons GR, Andersen RO, Abdi K, Song WS, Kuo CT | Cell reports | 24582961 | Cell Rep | 2014 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/24582961 |
Identification of distinct ChAT⁺ neurons and activity-dependent control of postnatal SVZ neurogenesis. | Paez-Gonzalez P, Asrican B, Rodriguez E, Kuo CT | Nature neuroscience | 24880216 | Nat Neurosci | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24880216 |
Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. | Benner EJ, Luciano D, Jo R, Abdi K, Paez-Gonzalez P, Sheng H, Warner DS, Liu C, Eroglu C, Kuo CT | Nature | 23615612 | Nature | 2013 May 16 | https://www.ncbi.nlm.nih.gov/pubmed/23615612 |
Ank3-dependent SVZ niche assembly is required for the continued production of new neurons. | Paez-Gonzalez P, Abdi K, Luciano D, Liu Y, Soriano-Navarro M, Rawlins E, Bennett V, Garcia-Verdugo JM, Kuo CT | Neuron | 21745638 | Neuron | 2011 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/21745638 |
Prefrontal cortex and executive function impairments in primary breast cancer. | Kesler SR, Kent JS, O'Hara R | Archives of neurology | 22084128 | Arch Neurol | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/22084128 |
Subjective cancer-related cognitive impairments and salience network connectivity in breast cancer survivors. | Henneghan AM, Kesler SR | Journal of cancer survivorship : research and practice | 36464750 | J Cancer Surviv | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/36464750 |
Brain network alterations and vulnerability to simulated neurodegeneration in breast cancer. | Kesler SR, Watson CL, Blayney DW | Neurobiology of aging | 26004016 | Neurobiol Aging | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26004016 |
Influence of choice of null network on small-world parameters of structural correlation networks. | Hosseini SM, Kesler SR | PloS one | 23840672 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23840672 |
GAT: a graph-theoretical analysis toolbox for analyzing between-group differences in large-scale structural and functional brain networks. | Hosseini SM, Hoeft F, Kesler SR | PloS one | 22808240 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22808240 |
Evidence of compensatory neural hyperactivity in a subgroup of chemotherapy-treated breast cancer survivors and its association with brain aging. | Mulholland MM, Stuifbergen A, De La Torre Schutz A, Franco Rocha OY, Blayney DW, Kesler SR | medRxiv : the preprint server for health sciences | 38712178 | medRxiv | 2024 Apr 22 | https://www.ncbi.nlm.nih.gov/pubmed/38712178 |
Cognitive profile of Turner syndrome. | Hong D, Scaletta Kent J, Kesler S | Developmental disabilities research reviews | 20014362 | Dev Disabil Res Rev | 2009 | https://www.ncbi.nlm.nih.gov/pubmed/20014362 |
The association of genetic polymorphisms with neuroconnectivity in breast cancer patients. | Harrison RA, Rao V, Kesler SR | Scientific reports | 33731765 | Sci Rep | 2021 Mar 17 | https://www.ncbi.nlm.nih.gov/pubmed/33731765 |
Altered resting state functional brain network topology in chemotherapy-treated breast cancer survivors. | Bruno J, Hosseini SM, Kesler S | Neurobiology of disease | 22820143 | Neurobiol Dis | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22820143 |
Reduced hippocampal volume and verbal memory performance associated with interleukin-6 and tumor necrosis factor-alpha levels in chemotherapy-treated breast cancer survivors. | Kesler S, Janelsins M, Koovakkattu D, Palesh O, Mustian K, Morrow G, Dhabhar FS | Brain, behavior, and immunity | 22698992 | Brain Behav Immun | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/22698992 |
Elevated prefrontal myo-inositol and choline following breast cancer chemotherapy. | Kesler SR, Watson C, Koovakkattu D, Lee C, O'Hara R, Mahaffey ML, Wefel JS | Brain imaging and behavior | 23536015 | Brain Imaging Behav | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23536015 |
Comparing connectivity pattern and small-world organization between structural correlation and resting-state networks in healthy adults. | Hosseini SM, Kesler SR | NeuroImage | 23603348 | Neuroimage | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23603348 |
Cognitive training for improving executive function in chemotherapy-treated breast cancer survivors. | Kesler S, Hadi Hosseini SM, Heckler C, Janelsins M, Palesh O, Mustian K, Morrow G | Clinical breast cancer | 23647804 | Clin Breast Cancer | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23647804 |
Functional connectome biotypes of chemotherapy-related cognitive impairment. | Kesler SR, Petersen ML, Rao V, Harrison RA, Palesh O | Journal of cancer survivorship : research and practice | 32157609 | J Cancer Surviv | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32157609 |
Predicting clinical outcome using brain activation associated with set-shifting and central coherence skills in Anorexia Nervosa. | Garrett AS, Lock J, Datta N, Beenhaker J, Kesler SR, Reiss AL | Journal of psychiatric research | 25027478 | J Psychiatr Res | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25027478 |
Default mode network connectivity distinguishes chemotherapy-treated breast cancer survivors from controls. | Kesler SR, Wefel JS, Hosseini SM, Cheung M, Watson CL, Hoeft F | Proceedings of the National Academy of Sciences of the United States of America | 23798392 | Proc Natl Acad Sci U S A | 2013 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/23798392 |
Multivariate pattern analysis of FMRI in breast cancer survivors and healthy women. | Hosseini SM, Kesler SR | Journal of the International Neuropsychological Society : JINS | 24135221 | J Int Neuropsychol Soc | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24135221 |
Altered small-world properties of gray matter networks in breast cancer. | Hosseini SM, Koovakkattu D, Kesler SR | BMC neurology | 22632066 | BMC Neurol | 2012 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/22632066 |
Anomalous gray matter structural networks in major depressive disorder. | Singh MK, Kesler SR, Hadi Hosseini SM, Kelley RG, Amatya D, Hamilton JP, Chen MC, Gotlib IH | Biological psychiatry | 23601854 | Biol Psychiatry | 2013 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/23601854 |
Neurotoxic Effects of Anthracycline- vs Nonanthracycline-Based Chemotherapy on Cognition in Breast Cancer Survivors. | Kesler SR, Blayney DW | JAMA oncology | 26633037 | JAMA Oncol | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26633037 |
Regional brain activation during verbal declarative memory in metastatic breast cancer. | Kesler SR, Bennett FC, Mahaffey ML, Spiegel D | Clinical cancer research : an official journal of the American Association for Cancer Research | 19843664 | Clin Cancer Res | 2009 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/19843664 |
Exploring Relationships Among Peripheral Amyloid Beta, Tau, Cytokines, Cognitive Function, and Psychosomatic Symptoms in Breast Cancer Survivors. | Henneghan A, Haley AP, Kesler S | Biological research for nursing | 31707784 | Biol Res Nurs | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31707784 |
Evidence of compensatory neural hyperactivity in a subgroup of breast cancer survivors treated with chemotherapy and its association with brain aging. | Mulholland MM, Stuifbergen A, De La Torre Schutz A, Franco Rocha OY, Blayney DW, Kesler SR | Frontiers in aging neuroscience | 39723153 | Front Aging Neurosci | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/39723153 |
Default mode network as a potential biomarker of chemotherapy-related brain injury. | Kesler SR | Neurobiology of aging | 24913897 | Neurobiol Aging | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/24913897 |
Task-based neurofeedback training: A novel approach toward training executive functions. | Hosseini SMH, Pritchard-Berman M, Sosa N, Ceja A, Kesler SR | NeuroImage | 27015711 | Neuroimage | 2016 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/27015711 |
MicroRNA profiling of human-induced pluripotent stem cells. | Wilson KD, Venkatasubrahmanyam S, Jia F, Sun N, Butte AJ, Wu JC | Stem cells and development | 19284351 | Stem Cells Dev | 2009 Jun | https://www.ncbi.nlm.nih.gov/pubmed/19284351 |
Effects of long-term culture on human embryonic stem cell aging. | Xie X, Hiona A, Lee AS, Cao F, Huang M, Li Z, Cherry A, Pei X, Wu JC | Stem cells and development | 20629482 | Stem Cells Dev | 2011 Jan | https://www.ncbi.nlm.nih.gov/pubmed/20629482 |
Sacrificial layer technique for axial force post assay of immature cardiomyocytes. | Taylor RE, Kim K, Sun N, Park SJ, Sim JY, Fajardo G, Bernstein D, Wu JC, Pruitt BL | Biomedical microdevices | 23007494 | Biomed Microdevices | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23007494 |
Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes. | Fu JD, Rushing SN, Lieu DK, Chan CW, Kong CW, Geng L, Wilson KD, Chiamvimonvat N, Boheler KR, Wu JC, Keller G, Hajjar RJ, Li RA | PloS one | 22110643 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22110643 |
Induced pluripotent stem cells as a disease modeling and drug screening platform. | Ebert AD, Liang P, Wu JC | Journal of cardiovascular pharmacology | 22240913 | J Cardiovasc Pharmacol | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22240913 |
Derivation of human induced pluripotent stem cells for cardiovascular disease modeling. | Narsinh K, Narsinh KH, Wu JC | Circulation research | 21527744 | Circ Res | 2011 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/21527744 |
Comparison of human induced pluripotent and embryonic stem cells: fraternal or identical twins? | Narsinh KH, Plews J, Wu JC | Molecular therapy : the journal of the American Society of Gene Therapy | 21455209 | Mol Ther | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21455209 |
Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells. | Lee AS, Xu D, Plews JR, Nguyen PK, Nag D, Lyons JK, Han L, Hu S, Lan F, Liu J, Huang M, Narsinh KH, Long CT, de Almeida PE, Levi B, Kooreman N, Bangs C, Pacharinsak C, Ikeno F, Yeung AC, Gambhir SS, Robbins RC, Longaker MT, Wu JC | The Journal of biological chemistry | 21719696 | J Biol Chem | 2011 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/21719696 |
Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. | Burridge PW, Keller G, Gold JD, Wu JC | Cell stem cell | 22226352 | Cell Stem Cell | 2012 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/22226352 |
Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells. | Ghosh Z, Wilson KD, Wu Y, Hu S, Quertermous T, Wu JC | PloS one | 20126639 | PLoS One | 2010 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/20126639 |
Epigenetic Modulations of Induced Pluripotent Stem Cells: Novel Therapies and Disease Models. | Huang C, Wu JC | Drug discovery today. Disease models | 23646061 | Drug Discov Today Dis Models | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23646061 |
Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns. | Sanchez-Freire V, Ebert AD, Kalisky T, Quake SR, Wu JC | Nature protocols | 22481529 | Nat Protoc | 2012 Apr 5 | https://www.ncbi.nlm.nih.gov/pubmed/22481529 |
A nonviral minicircle vector for deriving human iPS cells. | Jia F, Wilson KD, Sun N, Gupta DM, Huang M, Li Z, Panetta NJ, Chen ZY, Robbins RC, Kay MA, Longaker MT, Wu JC | Nature methods | 20139967 | Nat Methods | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20139967 |
Pushing the reset button: chemical-induced conversion of amniotic fluid stem cells into a pluripotent state. | Diecke S, Wu JC | Molecular therapy : the journal of the American Society of Gene Therapy | 23023056 | Mol Ther | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23023056 |
Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases. | Churko JM, Mantalas GL, Snyder MP, Wu JC | Circulation research | 23743227 | Circ Res | 2013 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/23743227 |
Safe genetic modification of cardiac stem cells using a site-specific integration technique. | Lan F, Liu J, Narsinh KH, Hu S, Han L, Lee AS, Karow M, Nguyen PK, Nag D, Calos MP, Robbins RC, Wu JC | Circulation | 22965984 | Circulation | 2012 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/22965984 |
Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. | Liang P, Lan F, Lee AS, Gong T, Sanchez-Freire V, Wang Y, Diecke S, Sallam K, Knowles JW, Wang PJ, Nguyen PK, Bers DM, Robbins RC, Wu JC | Circulation | 23519760 | Circulation | 2013 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/23519760 |
The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. | Sharma A, Diecke S, Zhang WY, Lan F, He C, Mordwinkin NM, Chua KF, Wu JC | The Journal of biological chemistry | 23653361 | J Biol Chem | 2013 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/23653361 |
Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors. | Narsinh KH, Jia F, Robbins RC, Kay MA, Longaker MT, Wu JC | Nature protocols | 21212777 | Nat Protoc | 2011 Jan | https://www.ncbi.nlm.nih.gov/pubmed/21212777 |
Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA. | Karow M, Chavez CL, Farruggio AP, Geisinger JM, Keravala A, Jung WE, Lan F, Wu JC, Chen-Tsai Y, Calos MP | Stem cells (Dayton, Ohio) | 21898697 | Stem Cells | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21898697 |
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. | Lan F, Lee AS, Liang P, Sanchez-Freire V, Nguyen PK, Wang L, Han L, Yen M, Wang Y, Sun N, Abilez OJ, Hu S, Ebert AD, Navarrete EG, Simmons CS, Wheeler M, Pruitt B, Lewis R, Yamaguchi Y, Ashley EA, Bers DM, Robbins RC, Longaker MT, Wu JC | Cell stem cell | 23290139 | Cell Stem Cell | 2013 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/23290139 |
Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation. | Gu M, Nguyen PK, Lee AS, Xu D, Hu S, Plews JR, Han L, Huber BC, Lee WH, Gong Y, de Almeida PE, Lyons J, Ikeno F, Pacharinsak C, Connolly AJ, Gambhir SS, Robbins RC, Longaker MT, Wu JC | Circulation research | 22821929 | Circ Res | 2012 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/22821929 |
Human iPS cell-based therapy: considerations before clinical applications. | Sun N, Longaker MT, Wu JC | Cell cycle (Georgetown, Tex.) | 20160515 | Cell Cycle | 2010 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/20160515 |
MicroRNA expression profiling of human-induced pluripotent and embryonic stem cells. | Sharma A, Wu JC | Methods in molecular biology (Clifton, N.J.) | 23007513 | Methods Mol Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23007513 |
MicroRNA-302 increases reprogramming efficiency via repression of NR2F2. | Hu S, Wilson KD, Ghosh Z, Han L, Wang Y, Lan F, Ransohoff KJ, Burridge P, Wu JC | Stem cells (Dayton, Ohio) | 23136034 | Stem Cells | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23136034 |
Atomic force mechanobiology of pluripotent stem cell-derived cardiomyocytes. | Liu J, Sun N, Bruce MA, Wu JC, Butte MJ | PloS one | 22624048 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22624048 |
Novel minicircle vector for gene therapy in murine myocardial infarction. | Huang M, Chen Z, Hu S, Jia F, Li Z, Hoyt G, Robbins RC, Kay MA, Wu JC | Circulation | 19752373 | Circulation | 2009 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/19752373 |
Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. | Navarrete EG, Liang P, Lan F, Sanchez-Freire V, Simmons C, Gong T, Sharma A, Burridge PW, Patlolla B, Lee AS, Wu H, Beygui RE, Wu SM, Robbins RC, Bers DM, Wu JC | Circulation | 24030418 | Circulation | 2013 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/24030418 |
Long term non-invasive imaging of embryonic stem cells using reporter genes. | Sun N, Lee A, Wu JC | Nature protocols | 19617890 | Nat Protoc | 2009 | https://www.ncbi.nlm.nih.gov/pubmed/19617890 |
Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging. | Wang Y, Zhang WY, Hu S, Lan F, Lee AS, Huber B, Lisowski L, Liang P, Huang M, de Almeida PE, Won JH, Sun N, Robbins RC, Kay MA, Urnov FD, Wu JC | Circulation research | 22967807 | Circ Res | 2012 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/22967807 |
In vivo directed differentiation of pluripotent stem cells for skeletal regeneration. | Levi B, Hyun JS, Montoro DT, Lo DD, Chan CK, Hu S, Sun N, Lee M, Grova M, Connolly AJ, Wu JC, Gurtner GC, Weissman IL, Wan DC, Longaker MT | Proceedings of the National Academy of Sciences of the United States of America | 23169671 | Proc Natl Acad Sci U S A | 2012 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/23169671 |
Dynamic microRNA expression during the transition from right ventricular hypertrophy to failure. | Reddy S, Zhao M, Hu DQ, Fajardo G, Hu S, Ghosh Z, Rajagopalan V, Wu JC, Bernstein D | Physiological genomics | 22454450 | Physiol Genomics | 2012 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/22454450 |
Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499. | Wilson KD, Hu S, Venkatasubrahmanyam S, Fu JD, Sun N, Abilez OJ, Baugh JJ, Jia F, Ghosh Z, Li RA, Butte AJ, Wu JC | Circulation. Cardiovascular genetics | 20733065 | Circ Cardiovasc Genet | 2010 Oct | https://www.ncbi.nlm.nih.gov/pubmed/20733065 |
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. | Sun N, Panetta NJ, Gupta DM, Wilson KD, Lee A, Jia F, Hu S, Cherry AM, Robbins RC, Longaker MT, Wu JC | Proceedings of the National Academy of Sciences of the United States of America | 19805220 | Proc Natl Acad Sci U S A | 2009 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/19805220 |
Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells. | Narsinh KH, Sun N, Sanchez-Freire V, Lee AS, Almeida P, Hu S, Jan T, Wilson KD, Leong D, Rosenberg J, Yao M, Robbins RC, Wu JC | The Journal of clinical investigation | 21317531 | J Clin Invest | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21317531 |
Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells. | Pearl JI, Lee AS, Leveson-Gower DB, Sun N, Ghosh Z, Lan F, Ransohoff J, Negrin RS, Davis MM, Wu JC | Cell stem cell | 21362570 | Cell Stem Cell | 2011 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/21362570 |
Functional characterization and expression profiling of human induced pluripotent stem cell- and embryonic stem cell-derived endothelial cells. | Li Z, Hu S, Ghosh Z, Han Z, Wu JC | Stem cells and development | 21235328 | Stem Cells Dev | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21235328 |
Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead. | Narsinh KH, Wu JC | Molecular therapy : the journal of the American Society of Gene Therapy | 20514030 | Mol Ther | 2010 Jun | https://www.ncbi.nlm.nih.gov/pubmed/20514030 |
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. | Sun N, Yazawa M, Liu J, Han L, Sanchez-Freire V, Abilez OJ, Navarrete EG, Hu S, Wang L, Lee A, Pavlovic A, Lin S, Chen R, Hajjar RJ, Snyder MP, Dolmetsch RE, Butte MJ, Ashley EA, Longaker MT, Robbins RC, Wu JC | Science translational medicine | 22517884 | Sci Transl Med | 2012 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/22517884 |
Dissecting the oncogenic and tumorigenic potential of differentiated human induced pluripotent stem cells and human embryonic stem cells. | Ghosh Z, Huang M, Hu S, Wilson KD, Dey D, Wu JC | Cancer research | 21646469 | Cancer Res | 2011 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/21646469 |
A suite of molecular markers for identifying species, detecting introgression and describing population structure in spadefoot toads (Spea spp.). | Pfennig KS, Allenby A, Martin RA, Monroy A, Jones CD | Molecular ecology resources | 22564443 | Mol Ecol Resour | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22564443 |
Leptin Manipulation Reduces Appetite and Causes a Switch in Mating Preference in the Plains Spadefoot Toad (Spea bombifrons). | Garcia NW, Pfennig KS, Burmeister SS | PloS one | 25919309 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25919309 |
Sexual selection's impacts on ecological specialization: an experimental test. | Pfennig KS, Pfennig DW, Porter C, Martin RA | Proceedings. Biological sciences | 25925102 | Proc Biol Sci | 2015 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/25925102 |
Age-dependent male mating investment in Drosophila pseudoobscura. | Dhole S, Pfennig KS | PloS one | 24586373 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24586373 |
Character displacement: ecological and reproductive responses to a common evolutionary problem. | Pfennig KS, Pfennig DW | The Quarterly review of biology | 19764283 | Q Rev Biol | 2009 Sep | https://www.ncbi.nlm.nih.gov/pubmed/19764283 |
Reinforcement generates reproductive isolation between neighbouring conspecific populations of spadefoot toads. | Pfennig KS, Rice AM | Proceedings. Biological sciences | 24990680 | Proc Biol Sci | 2014 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/24990680 |
Genome of Spea multiplicata, a Rapidly Developing, Phenotypically Plastic, and Desert-Adapted Spadefoot Toad. | Seidl F, Levis NA, Schell R, Pfennig DW, Pfennig KS, Ehrenreich IM | G3 (Bethesda, Md.) | 31578218 | G3 (Bethesda) | 2019 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/31578218 |
Monoaminergic integration of diet and social signals in the brains of juvenile spadefoot toads. | Burmeister SS, Rodriguez Moncalvo VG, Pfennig KS | The Journal of experimental biology | 28659306 | J Exp Biol | 2017 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/28659306 |
Vortex Formation and Foraging in Polyphenic Spadefoot Toad Tadpoles. | Bazazi S, Pfennig KS, Handegard NO, Couzin ID | Behavioral ecology and sociobiology | 23185101 | Behav Ecol Sociobiol | 2012 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23185101 |
Diet alters species recognition in juvenile toads. | Pfennig KS, Rodriguez Moncalvo VG, Burmeister SS | Biology letters | 24088562 | Biol Lett | 2013 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/24088562 |
Failed sperm development as a reproductive isolating barrier between species. | Wünsch LK, Pfennig KS | Evolution & development | 24261446 | Evol Dev | 2013 Nov-Dec | https://www.ncbi.nlm.nih.gov/pubmed/24261446 |
Development and evolution of character displacement. | Pfennig DW, Pfennig KS | Annals of the New York Academy of Sciences | 22257002 | Ann N Y Acad Sci | 2012 May | https://www.ncbi.nlm.nih.gov/pubmed/22257002 |
Variation in hybrid gene expression: Implications for the evolution of genetic incompatibilities in interbreeding species. | Seidl F, Levis NA, Jones CD, Monroy-Eklund A, Ehrenreich IM, Pfennig KS | Molecular ecology | 31541560 | Mol Ecol | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31541560 |
Social signals increase monoamine levels in the tegmentum of juvenile Mexican spadefoot toads (Spea multiplicata). | Rodriguez Moncalvo VG, Burmeister SS, Pfennig KS | Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology | 23681220 | J Comp Physiol A Neuroethol Sens Neural Behav Physiol | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23681220 |
Heterospecific interactions and the proliferation of sexually dimorphic traits. | Pfennig KS, Hurlbert AH | Current zoology | 24639684 | Curr Zool | 2012 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/24639684 |
Character displacement and the origins of diversity. | Pfennig DW, Pfennig KS | The American naturalist | 21043778 | Am Nat | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21043778 |
Relaxed genetic constraint is ancestral to the evolution of phenotypic plasticity. | Leichty AR, Pfennig DW, Jones CD, Pfennig KS | Integrative and comparative biology | 22526866 | Integr Comp Biol | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22526866 |
Differential encoding of signals and preferences by noradrenaline in the anuran brain. | Burmeister SS, Rodriguez Moncalvo VG, Pfennig KS | The Journal of experimental biology | 32647019 | J Exp Biol | 2020 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/32647019 |
Hybrid female mate choice as a species isolating mechanism: environment matters. | Schmidt EM, Pfennig KS | Journal of evolutionary biology | 26717048 | J Evol Biol | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26717048 |
Metabolism, cell growth and the bacterial cell cycle. | Wang JD, Levin PA | Nature reviews. Microbiology | 19806155 | Nat Rev Microbiol | 2009 Nov | https://www.ncbi.nlm.nih.gov/pubmed/19806155 |
DksA guards elongating RNA polymerase against ribosome-stalling-induced arrest. | Zhang Y, Mooney RA, Grass JA, Sivaramakrishnan P, Herman C, Landick R, Wang JD | Molecular cell | 24606919 | Mol Cell | 2014 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/24606919 |
Co-orientation of replication and transcription preserves genome integrity. | Srivatsan A, Tehranchi A, MacAlpine DM, Wang JD | PLoS genetics | 20090829 | PLoS Genet | 2010 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/20090829 |
The nature of mutations induced by replication–transcription collisions. | Sankar TS, Wastuwidyaningtyas BD, Dong Y, Lewis SA, Wang JD | Nature | 27362223 | Nature | 2016 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/27362223 |
ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications. | Hart MP, Gitler AD | The Journal of neuroscience : the official journal of the Society for Neuroscience | 22764223 | J Neurosci | 2012 Jul 4 | https://www.ncbi.nlm.nih.gov/pubmed/22764223 |
Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients. | Lee T, Li YR, Ingre C, Weber M, Grehl T, Gredal O, de Carvalho M, Meyer T, Tysnes OB, Auburger G, Gispert S, Bonini NM, Andersen PM, Gitler AD | Human molecular genetics | 21292779 | Hum Mol Genet | 2011 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/21292779 |
Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions. | Hart MP, Brettschneider J, Lee VM, Trojanowski JQ, Gitler AD | Acta neuropathologica | 22526021 | Acta Neuropathol | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22526021 |
Evaluating noncoding nucleotide repeat expansions in amyotrophic lateral sclerosis. | Figley MD, Thomas A, Gitler AD | Neurobiology of aging | 24269018 | Neurobiol Aging | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24269018 |
Yeast genetic screen reveals novel therapeutic strategy for ALS. | Figley MD, Gitler AD | Rare diseases (Austin, Tex.) | 25002991 | Rare Dis | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/25002991 |
Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics. | Figley MD, Bieri G, Kolaitis RM, Taylor JP, Gitler AD | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24920614 | J Neurosci | 2014 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/24920614 |
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. | Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Mojsilovic-Petrovic J, Panossian S, Kim CE, Frackelton EC, Solski JA, Williams KL, Clay-Falcone D, Elman L, McCluskey L, Greene R, Hakonarson H, Kalb RG, Lee VM, Trojanowski JQ, Nicholson GA, Blair IP, Bonini NM, Van Deerlin VM, Mourelatos Z, Shorter J, Gitler AD | Human molecular genetics | 22454397 | Hum Mol Genet | 2012 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/22454397 |
The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast. | Chesi A, Kilaru A, Fang X, Cooper AA, Gitler AD | PloS one | 22457822 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22457822 |
The modulation of Amyotrophic Lateral Sclerosis risk by ataxin-2 intermediate polyglutamine expansions is a specific effect. | Gispert S, Kurz A, Waibel S, Bauer P, Liepelt I, Geisen C, Gitler AD, Becker T, Weber M, Berg D, Andersen PM, Krüger R, Riess O, Ludolph AC, Auburger G | Neurobiology of disease | 21889984 | Neurobiol Dis | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/21889984 |
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. | King OD, Gitler AD, Shorter J | Brain research | 22445064 | Brain Res | 2012 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/22445064 |
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS. | Sun Z, Diaz Z, Fang X, Hart MP, Chesi A, Shorter J, Gitler AD | PLoS biology | 21541367 | PLoS Biol | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21541367 |
TDP-43 toxicity in yeast. | Armakola M, Hart MP, Gitler AD | Methods (San Diego, Calif.) | 21115123 | Methods | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21115123 |
PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats. | Yu Z, Zhu Y, Chen-Plotkin AS, Clay-Falcone D, McCluskey L, Elman L, Kalb RG, Trojanowski JQ, Lee VM, Van Deerlin VM, Gitler AD, Bonini NM | PloS one | 21479228 | PLoS One | 2011 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/21479228 |
Parkinson's Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein. | Dhungel N, Eleuteri S, Li LB, Kramer NJ, Chartron JW, Spencer B, Kosberg K, Fields JA, Stafa K, Adame A, Lashuel H, Frydman J, Shen K, Masliah E, Gitler AD | Neuron | 36603548 | Neuron | 2023 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/36603548 |
RNA-binding proteins with prion-like domains in ALS and FTLD-U. | Gitler AD, Shorter J | Prion | 21847013 | Prion | 2011 Jul-Sep | https://www.ncbi.nlm.nih.gov/pubmed/21847013 |
A yeast model for polyalanine-expansion aggregation and toxicity. | Konopka CA, Locke MN, Gallagher PS, Pham N, Hart MP, Walker CJ, Gitler AD, Gardner RG | Molecular biology of the cell | 21508314 | Mol Biol Cell | 2011 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/21508314 |
A yeast functional screen predicts new candidate ALS disease genes. | Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, Liu AX, Ramos D, Jethava N, Hosangadi D, Epstein J, Chiang A, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Solski JA, Williams KL, Mojsilovic-Petrovic J, Ingre C, Boylan K, Graff-Radford NR, Dickson DW, Clay-Falcone D, Elman L, McCluskey L, Greene R, Kalb RG, Lee VM, Trojanowski JQ, Ludolph A, Robberecht W, Andersen PM, Nicholson GA, Blair IP, King OD, Bonini NM, Van Deerlin V, Rademakers R, Mourelatos Z, Gitler AD | Proceedings of the National Academy of Sciences of the United States of America | 22065782 | Proc Natl Acad Sci U S A | 2011 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/22065782 |
Stress granules as crucibles of ALS pathogenesis. | Li YR, King OD, Shorter J, Gitler AD | The Journal of cell biology | 23629963 | J Cell Biol | 2013 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/23629963 |
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity. | Johnson BS, Snead D, Lee JJ, McCaffery JM, Shorter J, Gitler AD | The Journal of biological chemistry | 19465477 | J Biol Chem | 2009 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/19465477 |
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. | Elden AC, Kim HJ, Hart MP, Chen-Plotkin AS, Johnson BS, Fang X, Armakola M, Geser F, Greene R, Lu MM, Padmanabhan A, Clay-Falcone D, McCluskey L, Elman L, Juhr D, Gruber PJ, Rüb U, Auburger G, Trojanowski JQ, Lee VM, Van Deerlin VM, Bonini NM, Gitler AD | Nature | 20740007 | Nature | 2010 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/20740007 |
A template for new drugs against Alzheimer's disease. | Aguzzi A, Gitler AD | Cell | 24034239 | Cell | 2013 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/24034239 |
Exome sequencing to identify de novo mutations in sporadic ALS trios. | Chesi A, Staahl BT, Jovičić A, Couthouis J, Fasolino M, Raphael AR, Yamazaki T, Elias L, Polak M, Kelly C, Williams KL, Fifita JA, Maragakis NJ, Nicholson GA, King OD, Reed R, Crabtree GR, Blair IP, Glass JD, Gitler AD | Nature neuroscience | 23708140 | Nat Neurosci | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23708140 |
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. | Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV Jr, Gitler AD | Nature genetics | 23104007 | Nat Genet | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23104007 |
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. | Gitler AD, Chesi A, Geddie ML, Strathearn KE, Hamamichi S, Hill KJ, Caldwell KA, Caldwell GA, Cooper AA, Rochet JC, Lindquist S | Nature genetics | 19182805 | Nat Genet | 2009 Mar | https://www.ncbi.nlm.nih.gov/pubmed/19182805 |
High-throughput yeast plasmid overexpression screen. | Fleming MS, Gitler AD | Journal of visualized experiments : JoVE | 21841759 | J Vis Exp | 2011 Jul 27 | https://www.ncbi.nlm.nih.gov/pubmed/21841759 |
Model organisms reveal insight into human neurodegenerative disease: ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS. | Bonini NM, Gitler AD | Journal of molecular neuroscience : MN | 21660502 | J Mol Neurosci | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21660502 |
Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis. | Lee T, Li YR, Chesi A, Hart MP, Ramos D, Jethava N, Hosangadi D, Epstein J, Hodges B, Bonini NM, Gitler AD | Neurology | 21562248 | Neurology | 2011 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/21562248 |
Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models. | Kim HJ, Raphael AR, LaDow ES, McGurk L, Weber RA, Trojanowski JQ, Lee VM, Finkbeiner S, Gitler AD, Bonini NM | Nature genetics | 24336168 | Nat Genet | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24336168 |
Prion-like disorders: blurring the divide between transmissibility and infectivity. | Cushman M, Johnson BS, King OD, Gitler AD, Shorter J | Journal of cell science | 20356930 | J Cell Sci | 2010 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/20356930 |
Promises and pitfalls in cell replacement therapy for heart failure. | Krane M, Wernet O, Wu SM | Drug discovery today. Disease mechanisms | 21180399 | Drug Discov Today Dis Mech | 2010 Summer | https://www.ncbi.nlm.nih.gov/pubmed/21180399 |
iPS cell modeling of cardiometabolic diseases. | Nakamura K, Hirano K, Wu SM | Journal of cardiovascular translational research | 23070616 | J Cardiovasc Transl Res | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23070616 |
Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation. | Gregoire S, Karra R, Passer D, Deutsch MA, Krane M, Feistritzer R, Sturzu A, Domian I, Saga Y, Wu SM | Circulation research | 23307821 | Circ Res | 2013 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/23307821 |
Induced pluripotent stem cell modeling of complex genetic diseases. | Hinson JT, Nakamura K, Wu SM | Drug discovery today. Disease models | 23690830 | Drug Discov Today Dis Models | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23690830 |
Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes. | Tarnawski L, Xian X, Monnerat G, Macaulay IC, Malan D, Borgman A, Wu SM, Fleischmann BK, Jovinge S | PloS one | 26323090 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26323090 |
Derivation of highly purified cardiomyocytes from human induced pluripotent stem cells using small molecule-modulated differentiation and subsequent glucose starvation. | Sharma A, Li G, Rajarajan K, Hamaguchi R, Burridge PW, Wu SM | Journal of visualized experiments : JoVE | 25867738 | J Vis Exp | 2015 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/25867738 |
Identification of cardiovascular lineage descendants at single-cell resolution. | Li G, Plonowska K, Kuppusamy R, Sturzu A, Wu SM | Development (Cambridge, England) | 25633351 | Development | 2015 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/25633351 |
Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. | Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE | Cell reports | 28009297 | Cell Rep | 2016 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/28009297 |
Pharmacological inhibition of TGFβ receptor improves Nkx2.5 cardiomyoblast-mediated regeneration. | Chen WP, Liu YH, Ho YJ, Wu SM | Cardiovascular research | 25362681 | Cardiovasc Res | 2015 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/25362681 |
Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss. | Sturzu AC, Rajarajan K, Passer D, Plonowska K, Riley A, Tan TC, Sharma A, Xu AF, Engels MC, Feistritzer R, Li G, Selig MK, Geissler R, Robertson KD, Scherrer-Crosbie M, Domian IJ, Wu SM | Circulation | 25995316 | Circulation | 2015 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/25995316 |
Nkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal Heart. | Serpooshan V, Liu YH, Buikema JW, Galdos FX, Chirikian O, Paige S, Venkatraman S, Kumar A, Rawnsley DR, Huang X, Pijnappels DA, Wu SM | Scientific reports | 28974782 | Sci Rep | 2017 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/28974782 |
Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform. | Sharma A, Marceau C, Hamaguchi R, Burridge PW, Rajarajan K, Churko JM, Wu H, Sallam KI, Matsa E, Sturzu AC, Che Y, Ebert A, Diecke S, Liang P, Red-Horse K, Carette JE, Wu SM, Wu JC | Circulation research | 25015077 | Circ Res | 2014 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/25015077 |
Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes. | Buikema JW, Lee S, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, Paige SL, Lee D, Wu H, Paik DT, Rhee S, Tian L, Galdos FX, Puluca N, Beyersdorf B, Hu J, Beck A, Venkamatran S, Swami S, Wijnker P, Schuldt M, Dorsch LM, van Mil A, Red-Horse K, Wu JY, Geisen C, Hesse M, Serpooshan V, Jovinge S, Fleischmann BK, Doevendans PA, van der Velden J, Garcia KC, Wu JC, Sluijter JPG, Wu SM | Cell stem cell | 32619518 | Cell Stem Cell | 2020 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/32619518 |
Origin of cardiac progenitor cells in the developing and postnatal heart. | Kuhn EN, Wu SM | Journal of cellular physiology | 20568226 | J Cell Physiol | 2010 Nov | https://www.ncbi.nlm.nih.gov/pubmed/20568226 |
Harnessing the potential of induced pluripotent stem cells for regenerative medicine. | Wu SM, Hochedlinger K | Nature cell biology | 21540845 | Nat Cell Biol | 2011 May | https://www.ncbi.nlm.nih.gov/pubmed/21540845 |
Somatic Cell Reprogramming into Cardiovascular Lineages. | Chen JX, Plonowska K, Wu SM | Journal of cardiovascular pharmacology and therapeutics | 24764131 | J Cardiovasc Pharmacol Ther | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24764131 |
Of fish and men: clonal lineage analysis identifies divergence in myocardial development. | Sharma A, Wu SM | Circulation research | 23410876 | Circ Res | 2013 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/23410876 |
Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes. | Maas RGC, Lee S, Harakalova M, Snijders Blok CJB, Goodyer WR, Hjortnaes J, Doevendans PAFM, Van Laake LW, van der Velden J, Asselbergs FW, Wu JC, Sluijter JPG, Wu SM, Buikema JW | STAR protocols | 33615277 | STAR Protoc | 2021 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/33615277 |
Epigenetic mechanisms in cardiac development and disease. | Vallaster M, Vallaster CD, Wu SM | Acta biochimica et biophysica Sinica | 22194017 | Acta Biochim Biophys Sin (Shanghai) | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22194017 |
Developmental and regenerative biology of multipotent cardiovascular progenitor cells. | Sturzu AC, Wu SM | Circulation research | 21293007 | Circ Res | 2011 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/21293007 |
Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening. | Sharma A, Wu JC, Wu SM | Stem cell research & therapy | 24476344 | Stem Cell Res Ther | 2013 Dec 24 | https://www.ncbi.nlm.nih.gov/pubmed/24476344 |
Insulin-like growth factor promotes cardiac lineage induction in vitro by selective expansion of early mesoderm. | Engels MC, Rajarajan K, Feistritzer R, Sharma A, Nielsen UB, Schalij MJ, de Vries AA, Pijnappels DA, Wu SM | Stem cells (Dayton, Ohio) | 24496962 | Stem Cells | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24496962 |
Isolation and functional characterization of pluripotent stem cell-derived cardiac progenitor cells. | Huang X, Wu SM | Current protocols in stem cell biology | 20814937 | Curr Protoc Stem Cell Biol | 2010 Sep | https://www.ncbi.nlm.nih.gov/pubmed/20814937 |
Reprogramming the beat: kicking it up a notch. | Wu SM, Milan DJ | Circulation | 22837161 | Circulation | 2012 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/22837161 |
At a crossroad: cell therapy for cardiac repair. | Deutsch MA, Sturzu A, Wu SM | Circulation research | 23493304 | Circ Res | 2013 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/23493304 |
VISIONS: the art of science. | Wu SM | Molecular reproduction and development | 19358263 | Mol Reprod Dev | 2009 Jun | https://www.ncbi.nlm.nih.gov/pubmed/19358263 |
The integrative aspects of cardiac physiology and their implications for cell-based therapy. | Pijnappels DA, Gregoire S, Wu SM | Annals of the New York Academy of Sciences | 20201880 | Ann N Y Acad Sci | 2010 Feb | https://www.ncbi.nlm.nih.gov/pubmed/20201880 |
YY1 Expression Is Sufficient for the Maintenance of Cardiac Progenitor Cell State. | Gregoire S, Li G, Sturzu AC, Schwartz RJ, Wu SM | Stem cells (Dayton, Ohio) | 28580685 | Stem Cells | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28580685 |
Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons. | Chuang W, Sharma A, Shukla P, Li G, Mall M, Rajarajan K, Abilez OJ, Hamaguchi R, Wu JC, Wernig M, Wu SM | Scientific reports | 28327614 | Sci Rep | 2017 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/28327614 |
Reprogramming of mouse, rat, pig, and human fibroblasts into iPS cells. | Rajarajan K, Engels MC, Wu SM | Current protocols in molecular biology | 22237859 | Curr Protoc Mol Biol | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22237859 |
Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. | Chen JX, Krane M, Deutsch MA, Wang L, Rav-Acha M, Gregoire S, Engels MC, Rajarajan K, Karra R, Abel ED, Wu JC, Milan D, Wu SM | Circulation research | 22581928 | Circ Res | 2012 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/22581928 |
Small molecule regulators of postnatal Nkx2.5 cardiomyoblast proliferation and differentiation. | Chen WP, Wu SM | Journal of cellular and molecular medicine | 22212626 | J Cell Mol Med | 2012 May | https://www.ncbi.nlm.nih.gov/pubmed/22212626 |
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. | Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC | Science translational medicine | 28202772 | Sci Transl Med | 2017 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/28202772 |
TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance. | Luo S, Kleemann GA, Ashraf JM, Shaw WM, Murphy CT | Cell | 20946987 | Cell | 2010 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/20946987 |
The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling. | Shaw WM, Luo S, Landis J, Ashraf J, Murphy CT | Current biology : CB | 17900898 | Curr Biol | 2007 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/17900898 |
An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology. | Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q | PLoS genetics | 24675767 | PLoS Genet | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24675767 |
Mating induces shrinking and death in Caenorhabditis mothers. | Shi C, Murphy CT | Science (New York, N.Y.) | 24356112 | Science | 2014 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/24356112 |
PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity. | Tepper RG, Ashraf J, Kaletsky R, Kleemann G, Murphy CT, Bussemaker HJ | Cell | 23911329 | Cell | 2013 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/23911329 |
Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. | Moore RS, Kaletsky R, Murphy CT | Cell | 31178117 | Cell | 2019 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/31178117 |
Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. | Templeman NM, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy CT | Current biology : CB | 29478855 | Curr Biol | 2018 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/29478855 |
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Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO. | Landis JN, Murphy CT | Developmental dynamics : an official publication of the American Association of Anatomists | 20140911 | Dev Dyn | 2010 May | https://www.ncbi.nlm.nih.gov/pubmed/20140911 |
Caenorhabditis elegans reproductive aging: Regulation and underlying mechanisms. | Luo S, Murphy CT | Genesis (New York, N.Y. : 2000) | 21105070 | Genesis | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/21105070 |
CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling. | Templeman NM, Cota V, Keyes W, Kaletsky R, Murphy CT | Developmental cell | 32544391 | Dev Cell | 2020 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/32544391 |
Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. | Arey RN, Kaletsky R, Murphy CT | Scientific reports | 31889133 | Sci Rep | 2019 Dec 30 | https://www.ncbi.nlm.nih.gov/pubmed/31889133 |
A microfluidic device and automatic counting system for the study of C. elegans reproductive aging. | Li S, Stone HA, Murphy CT | Lab on a chip | 25407755 | Lab Chip | 2015 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/25407755 |
The metabolic enzyme CTP synthase forms cytoskeletal filaments. | Ingerson-Mahar M, Briegel A, Werner JN, Jensen GJ, Gitai Z | Nature cell biology | 20639870 | Nat Cell Biol | 2010 Aug | https://www.ncbi.nlm.nih.gov/pubmed/20639870 |
BapE DNA endonuclease induces an apoptotic-like response to DNA damage in Caulobacter. | Bos J, Yakhnina AA, Gitai Z | Proceedings of the National Academy of Sciences of the United States of America | 23074244 | Proc Natl Acad Sci U S A | 2012 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/23074244 |
Filament depolymerization can explain chromosome pulling during bacterial mitosis. | Banigan EJ, Gelbart MA, Gitai Z, Wingreen NS, Liu AJ | PLoS computational biology | 21966261 | PLoS Comput Biol | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21966261 |
Specific control of Pseudomonas aeruginosa surface-associated behaviors by two c-di-GMP diguanylate cyclases. | Merritt JH, Ha DG, Cowles KN, Lu W, Morales DK, Rabinowitz J, Gitai Z, O'Toole GA | mBio | 20978535 | mBio | 2010 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/20978535 |
Image analysis in fluorescence microscopy: bacterial dynamics as a case study. | van Teeffelen S, Shaevitz JW, Gitai Z | BioEssays : news and reviews in molecular, cellular and developmental biology | 22415868 | Bioessays | 2012 May | https://www.ncbi.nlm.nih.gov/pubmed/22415868 |
The putative Poc complex controls two distinct Pseudomonas aeruginosa polar motility mechanisms. | Cowles KN, Moser TS, Siryaporn A, Nyakudarika N, Dixon W, Turner JJ, Gitai Z | Molecular microbiology | 24102920 | Mol Microbiol | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24102920 |
New fluorescence microscopy methods for microbiology: sharper, faster, and quantitative. | Gitai Z | Current opinion in microbiology | 19356974 | Curr Opin Microbiol | 2009 Jun | https://www.ncbi.nlm.nih.gov/pubmed/19356974 |
A growing family: the expanding universe of the bacterial cytoskeleton. | Ingerson-Mahar M, Gitai Z | FEMS microbiology reviews | 22092065 | FEMS Microbiol Rev | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22092065 |
Surface association and the MreB cytoskeleton regulate pilus production, localization and function in Pseudomonas aeruginosa. | Cowles KN, Gitai Z | Molecular microbiology | 20398206 | Mol Microbiol | 2010 Jun | https://www.ncbi.nlm.nih.gov/pubmed/20398206 |
Caulobacter chromosome segregation is an ordered multistep process. | Shebelut CW, Guberman JM, van Teeffelen S, Yakhnina AA, Gitai Z | Proceedings of the National Academy of Sciences of the United States of America | 20660743 | Proc Natl Acad Sci U S A | 2010 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/20660743 |
The small protein MbiA interacts with MreB and modulates cell shape in Caulobacter crescentus. | Yakhnina AA, Gitai Z | Molecular microbiology | 22804814 | Mol Microbiol | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22804814 |
Beyond the cytoskeleton: mesoscale assemblies and their function in spatial organization. | Wilson MZ, Gitai Z | Current opinion in microbiology | 23601587 | Curr Opin Microbiol | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23601587 |
Bacterial evolution: rewiring modules to get in shape. | Persat A, Gitai Z | Current biology : CB | 24892912 | Curr Biol | 2014 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/24892912 |
Colonization, competition, and dispersal of pathogens in fluid flow networks. | Siryaporn A, Kim MK, Shen Y, Stone HA, Gitai Z | Current biology : CB | 25843031 | Curr Biol | 2015 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/25843031 |
Surface attachment induces Pseudomonas aeruginosa virulence. | Siryaporn A, Kuchma SL, O'Toole GA, Gitai Z | Proceedings of the National Academy of Sciences of the United States of America | 25385640 | Proc Natl Acad Sci U S A | 2014 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/25385640 |
Dynamic polar sequestration of excess MurG may regulate enzymatic function. | Michaelis AM, Gitai Z | Journal of bacteriology | 20644141 | J Bacteriol | 2010 Sep | https://www.ncbi.nlm.nih.gov/pubmed/20644141 |
Draft Genome Sequence of Uropathogenic Escherichia coli Strain J96. | Klein EA, Gitai Z | Genome announcements | 23469357 | Genome Announc | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23469357 |
Physiological role of stalk lengthening in Caulobacter crescentus. | Klein EA, Schlimpert S, Hughes V, Brun YV, Thanbichler M, Gitai Z | Communicative & integrative biology | 23986806 | Commun Integr Biol | 2013 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/23986806 |
General protein diffusion barriers create compartments within bacterial cells. | Schlimpert S, Klein EA, Briegel A, Hughes V, Kahnt J, Bolte K, Maier UG, Brun YV, Jensen GJ, Gitai Z, Thanbichler M | Cell | 23201141 | Cell | 2012 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/23201141 |
Diverse functions for six glycosyltransferases in Caulobacter crescentus cell wall assembly. | Yakhnina AA, Gitai Z | Journal of bacteriology | 23935048 | J Bacteriol | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23935048 |
The curved shape of Caulobacter crescentus enhances surface colonization in flow. | Persat A, Stone HA, Gitai Z | Nature communications | 24806788 | Nat Commun | 2014 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/24806788 |
High-throughput screening of bacterial protein localization. | Werner JN, Gitai Z | Methods in enzymology | 20946849 | Methods Enzymol | 2010 | https://www.ncbi.nlm.nih.gov/pubmed/20946849 |
Flow directs surface-attached bacteria to twitch upstream. | Shen Y, Siryaporn A, Lecuyer S, Gitai Z, Stone HA | Biophysical journal | 22828341 | Biophys J | 2012 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/22828341 |
Self-assembling enzymes and the origins of the cytoskeleton. | Barry RM, Gitai Z | Current opinion in microbiology | 22014508 | Curr Opin Microbiol | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22014508 |
Enzyme clustering accelerates processing of intermediates through metabolic channeling. | Castellana M, Wilson MZ, Xu Y, Joshi P, Cristea IM, Rabinowitz JD, Gitai Z, Wingreen NS | Nature biotechnology | 25262299 | Nat Biotechnol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25262299 |
Mode of action and resistance studies unveil new roles for tropodithietic acid as an anticancer agent and the γ-glutamyl cycle as a proton sink. | Wilson MZ, Wang R, Gitai Z, Seyedsayamdost MR | Proceedings of the National Academy of Sciences of the United States of America | 26802120 | Proc Natl Acad Sci U S A | 2016 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/26802120 |
Specific chemotaxis of magnetically labeled mesenchymal stem cells: implications for MRI of glioma. | Bennewitz MF, Tang KS, Markakis EA, Shapiro EM | Molecular imaging and biology | 22418788 | Mol Imaging Biol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22418788 |
Poly(lactic-co-glycolic acid) encapsulated gadolinium oxide nanoparticles for MRI-based cell tracking. | Bennewitz MF, Williams SS, Nkansah MK, Shapiro EM | Journal of nanoscience and nanotechnology | 23862407 | J Nanosci Nanotechnol | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23862407 |
Clinically viable magnetic poly(lactide-co-glycolide) particles for MRI-based cell tracking. | Granot D, Nkansah MK, Bennewitz MF, Tang KS, Markakis EA, Shapiro EM | Magnetic resonance in medicine | 23568825 | Magn Reson Med | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23568825 |
Biodegradable, polymer encapsulated, metal oxide particles for MRI-based cell tracking. | Shapiro EM | Magnetic resonance in medicine | 24753150 | Magn Reson Med | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24753150 |
The effect of cryoprotection on the use of PLGA encapsulated iron oxide nanoparticles for magnetic cell labeling. | Tang KS, Hashmi SM, Shapiro EM | Nanotechnology | 23459030 | Nanotechnology | 2013 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/23459030 |
Magnetic poly(lactide-co-glycolide) and cellulose particles for MRI-based cell tracking. | Nkansah MK, Thakral D, Shapiro EM | Magnetic resonance in medicine | 21404328 | Magn Reson Med | 2011 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21404328 |
In vivo serial MRI of age-dependent neural progenitor cell migration in the rat brain. | Shuboni-Mulligan DD, Chakravarty S, Mallett CL, Wolf AM, Dmitriev PM, Forton SM, Shapiro EM | NeuroImage | 31152841 | Neuroimage | 2019 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/31152841 |
On Automated Source Selection for Transfer Learning in Convolutional Neural Networks. | Afridi MJ, Ross A, Shapiro EM | Pattern recognition | 30774153 | Pattern Recognit | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30774153 |
Accumulation of micron sized iron oxide particles in endothelin-1 induced focal cortical ischemia in rats is independent of cell migration. | Granot D, Shapiro EM | Magnetic resonance in medicine | 23661604 | Magn Reson Med | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23661604 |
Release activation of iron oxide nanoparticles: (REACTION) a novel environmentally sensitive MRI paradigm. | Granot D, Shapiro EM | Magnetic resonance in medicine | 21360745 | Magn Reson Med | 2011 May | https://www.ncbi.nlm.nih.gov/pubmed/21360745 |
Acquired resistance of EGFR-mutant lung adenocarcinomas to afatinib plus cetuximab is associated with activation of mTORC1. | Pirazzoli V, Nebhan C, Song X, Wurtz A, Walther Z, Cai G, Zhao Z, Jia P, de Stanchina E, Shapiro EM, Gale M, Yin R, Horn L, Carbone DP, Stephens PJ, Miller V, Gettinger S, Pao W, Politi K | Cell reports | 24813888 | Cell Rep | 2014 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/24813888 |
Fabrication of magnetic and fluorescent chitin and dibutyrylchitin sub-micron particles by oil-in-water emulsification. | Blanco-Fernandez B, Chakravarty S, Nkansah MK, Shapiro EM | Acta biomaterialia | 27592817 | Acta Biomater | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27592817 |
Intelligent and automatic in vivo detection and quantification of transplanted cells in MRI. | Afridi MJ, Ross A, Liu X, Bennewitz MF, Shuboni DD, Shapiro EM | Magnetic resonance in medicine | 28019017 | Magn Reson Med | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28019017 |
On the use of micron-sized iron oxide particles (MPIOS) to label resting monocytes in bone marrow. | Tang KS, Hann B, Shapiro EM | Molecular imaging and biology | 20936363 | Mol Imaging Biol | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/20936363 |
Dual-modality, fluorescent, PLGA encapsulated bismuth nanoparticles for molecular and cellular fluorescence imaging and computed tomography. | Swy ER, Schwartz-Duval AS, Shuboni DD, Latourette MT, Mallet CL, Parys M, Cormode DP, Shapiro EM | Nanoscale | 25248645 | Nanoscale | 2014 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/25248645 |
Enhanced magnetic cell labeling efficiency using -NH2 coated MPIOs. | Tang KS, Shapiro EM | Magnetic resonance in medicine | 21446031 | Magn Reson Med | 2011 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21446031 |
Biocompatible and pH-sensitive PLGA encapsulated MnO nanocrystals for molecular and cellular MRI. | Bennewitz MF, Lobo TL, Nkansah MK, Ulas G, Brudvig GW, Shapiro EM | ACS nano | 21495676 | ACS Nano | 2011 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/21495676 |
Serial monitoring of endogenous neuroblast migration by cellular MRI. | Granot D, Scheinost D, Markakis EA, Papademetris X, Shapiro EM | NeuroImage | 21571076 | Neuroimage | 2011 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/21571076 |
Mapping of long-range associations throughout the fission yeast genome reveals global genome organization linked to transcriptional regulation. | Tanizawa H, Iwasaki O, Tanaka A, Capizzi JR, Wickramasinghe P, Lee M, Fu Z, Noma K | Nucleic acids research | 21030438 | Nucleic Acids Res | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21030438 |
Epigenetic regulation of condensin-mediated genome organization during the cell cycle and upon DNA damage through histone H3 lysine 56 acetylation. | Tanaka A, Tanizawa H, Sriswasdi S, Iwasaki O, Chatterjee AG, Speicher DW, Levin HL, Noguchi E, Noma K | Molecular cell | 23084836 | Mol Cell | 2012 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/23084836 |
Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes. | Iwasaki O, Tanizawa H, Kim KD, Yokoyama Y, Corcoran CJ, Tanaka A, Skordalakes E, Showe LC, Noma K | Molecular cell | 26257282 | Mol Cell | 2015 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/26257282 |
Centromeric motion facilitates the mobility of interphase genomic regions in fission yeast. | Kim KD, Tanizawa H, Iwasaki O, Corcoran CJ, Capizzi JR, Hayden JE, Noma K | Journal of cell science | 23986481 | J Cell Sci | 2013 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/23986481 |
Condensin-mediated chromosome organization in fission yeast. | Iwasaki O, Noma KI | Current genetics | 27061734 | Curr Genet | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27061734 |
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Global genome organization mediated by RNA polymerase III-transcribed genes in fission yeast. | Iwasaki O, Noma K | Gene | 21195141 | Gene | 2012 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/21195141 |
Architectural alterations of the fission yeast genome during the cell cycle. | Tanizawa H, Kim KD, Iwasaki O, Noma KI | Nature structural & molecular biology | 28991264 | Nat Struct Mol Biol | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28991264 |
Centromeric localization of dispersed Pol III genes in fission yeast. | Iwasaki O, Tanaka A, Tanizawa H, Grewal SI, Noma K | Molecular biology of the cell | 19910488 | Mol Biol Cell | 2010 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/19910488 |
New vectors for epitope tagging and gene disruption in Schizosaccharomyces pombe. | Gadaleta MC, Iwasaki O, Noguchi C, Noma K, Noguchi E | BioTechniques | 24215641 | Biotechniques | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24215641 |
The Yeast Genomes in Three Dimensions: Mechanisms and Functions. | Noma KI | Annual review of genetics | 28853923 | Annu Rev Genet | 2017 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/28853923 |
Unravelling global genome organization by 3C-seq. | Tanizawa H, Noma K | Seminars in cell & developmental biology | 22120510 | Semin Cell Dev Biol | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22120510 |
An IF-FISH Approach for Covisualization of Gene Loci and Nuclear Architecture in Fission Yeast. | Kim KD, Iwasaki O, Noma K | Methods in enzymology | 27423862 | Methods Enzymol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27423862 |
Involvement of condensin-directed gene associations in the organization and regulation of chromosome territories during the cell cycle. | Iwasaki O, Corcoran CJ, Noma K | Nucleic acids research | 26704981 | Nucleic Acids Res | 2016 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/26704981 |
Transcription factors mediate condensin recruitment and global chromosomal organization in fission yeast. | Kim KD, Tanizawa H, Iwasaki O, Noma K | Nature genetics | 27548313 | Nat Genet | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27548313 |
Enzymatically triggered actuation of miniaturized tools. | Bassik N, Brafman A, Zarafshar AM, Jamal M, Luvsanjav D, Selaru FM, Gracias DH | Journal of the American Chemical Society | 20849106 | J Am Chem Soc | 2010 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/20849106 |
Differentially photo-crosslinked polymers enable self-assembling microfluidics. | Jamal M, Zarafshar AM, Gracias DH | Nature communications | 22068594 | Nat Commun | 2011 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/22068594 |
Self-folding polymeric containers for encapsulation and delivery of drugs. | Fernandes R, Gracias DH | Advanced drug delivery reviews | 22425612 | Adv Drug Deliv Rev | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/22425612 |
Directed growth of fibroblasts into three dimensional micropatterned geometries via self-assembling scaffolds. | Jamal M, Bassik N, Cho JH, Randall CL, Gracias DH | Biomaterials | 20022106 | Biomaterials | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20022106 |
Stimuli-responsive theragrippers for chemomechanical controlled release. | Malachowski K, Breger J, Kwag HR, Wang MO, Fisher JP, Selaru FM, Gracias DH | Angewandte Chemie (International ed. in English) | 24634136 | Angew Chem Int Ed Engl | 2014 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/24634136 |
Biopsy using a magnetic capsule endoscope carrying, releasing, and retrieving untethered microgrippers. | Yim S, Gultepe E, Gracias DH, Sitti M | IEEE transactions on bio-medical engineering | 24108454 | IEEE Trans Biomed Eng | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24108454 |
Curving nanostructures using extrinsic stress. | Cho JH, James T, Gracias DH | Advanced materials (Deerfield Beach, Fla.) | 20376856 | Adv Mater | 2010 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/20376856 |
Plastic deformation drives wrinkling, saddling, and wedging of annular bilayer nanostructures. | Cho JH, Datta D, Park SY, Shenoy VB, Gracias DH | Nano letters | 21090597 | Nano Lett | 2010 Dec 8 | https://www.ncbi.nlm.nih.gov/pubmed/21090597 |
Enabling cargo-carrying bacteria via surface attachment and triggered release. | Fernandes R, Zuniga M, Sassine FR, Karakoy M, Gracias DH | Small (Weinheim an der Bergstrasse, Germany) | 21370460 | Small | 2011 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/21370460 |
Bio-origami hydrogel scaffolds composed of photocrosslinked PEG bilayers. | Jamal M, Kadam SS, Xiao R, Jivan F, Onn TM, Fernandes R, Nguyen TD, Gracias DH | Advanced healthcare materials | 23386382 | Adv Healthc Mater | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23386382 |
Self-folding single cell grippers. | Malachowski K, Jamal M, Jin Q, Polat B, Morris CJ, Gracias DH | Nano letters | 24937214 | Nano Lett | 2014 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/24937214 |
Three-dimensional chemical patterns for cellular self-organization. | Kalinin YV, Randhawa JS, Gracias DH | Angewandte Chemie (International ed. in English) | 21370335 | Angew Chem Int Ed Engl | 2011 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/21370335 |
Self-folding devices and materials for biomedical applications. | Randall CL, Gultepe E, Gracias DH | Trends in biotechnology | 21764161 | Trends Biotechnol | 2012 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21764161 |
3D printed bionic ears. | Mannoor MS, Jiang Z, James T, Kong YL, Malatesta KA, Soboyejo WO, Verma N, Gracias DH, McAlpine MC | Nano letters | 23635097 | Nano Lett | 2013 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/23635097 |
Three-dimensional fabrication at small size scales. | Leong TG, Zarafshar AM, Gracias DH | Small (Weinheim an der Bergstrasse, Germany) | 20349446 | Small | 2010 Apr 9 | https://www.ncbi.nlm.nih.gov/pubmed/20349446 |
Reversible actuation of microstructures by surface-chemical modification of thin-film bilayers. | Randhawa JS, Keung MD, Tyagi P, Gracias DH | Advanced materials (Deerfield Beach, Fla.) | 20217729 | Adv Mater | 2010 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/20217729 |
Patternable nanowire sensors for electrochemical recording of dopamine. | Tyagi P, Postetter D, Saragnese DL, Randall CL, Mirski MA, Gracias DH | Analytical chemistry | 19904993 | Anal Chem | 2009 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/19904993 |
Biopsy with thermally-responsive untethered microtools. | Gultepe E, Randhawa JS, Kadam S, Yamanaka S, Selaru FM, Shin EJ, Kalloo AN, Gracias DH | Advanced materials (Deerfield Beach, Fla.) | 23047708 | Adv Mater | 2013 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/23047708 |
Silane surface modification for improved bioadhesion of esophageal stents. | Karakoy M, Gultepe E, Pandey S, Khashab MA, Gracias DH | Applied surface science | 25663731 | Appl Surf Sci | 2014 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/25663731 |
Self-folding thermo-magnetically responsive soft microgrippers. | Breger JC, Yoon C, Xiao R, Kwag HR, Wang MO, Fisher JP, Nguyen TD, Gracias DH | ACS applied materials & interfaces | 25594664 | ACS Appl Mater Interfaces | 2015 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/25594664 |
Microassembly based on hands free origami with bidirectional curvature. | Bassik N, Stern GM, Gracias DH | Applied physics letters | 19787072 | Appl Phys Lett | 2009 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/19787072 |
Three dimensional nanofabrication using surface forces. | Cho JH, Azam A, Gracias DH | Langmuir : the ACS journal of surfaces and colloids | 20507147 | Langmuir | 2010 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/20507147 |
Chemistry with spatial control using particles and streams(). | Kalinin YV, Murali A, Gracias DH | RSC advances | 23145348 | RSC Adv | 2012 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/23145348 |
Hierarchical self-assembly of complex polyhedral microcontainers. | Filipiak DJ, Azam A, Leong TG, Gracias DH | Journal of micromechanics and microengineering : structures, devices, and systems | 20161118 | J Micromech Microeng | 2009 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/20161118 |
Self-folding micropatterned polymeric containers. | Azam A, Laflin KE, Jamal M, Fernandes R, Gracias DH | Biomedical microdevices | 20838901 | Biomed Microdevices | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/20838901 |
Three-dimensional microwell arrays for cell culture. | Randall CL, Kalinin YV, Jamal M, Manohar T, Gracias DH | Lab on a chip | 21063585 | Lab Chip | 2011 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/21063585 |
Self-assembly of lithographically patterned nanoparticles. | Cho JH, Gracias DH | Nano letters | 19681638 | Nano Lett | 2009 Dec | https://www.ncbi.nlm.nih.gov/pubmed/19681638 |
Voltage-gated ion transport through semiconducting conical nanopores formed by metal nanoparticle-assisted plasma etching. | James T, Kalinin YV, Chan CC, Randhawa JS, Gaevski M, Gracias DH | Nano letters | 22725714 | Nano Lett | 2012 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/22725714 |
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. | Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, Apostolou E, Stadtfeld M, Li Y, Shioda T, Natesan S, Wagers AJ, Melnick A, Evans T, Hochedlinger K | Nature biotechnology | 20644536 | Nat Biotechnol | 2010 Aug | https://www.ncbi.nlm.nih.gov/pubmed/20644536 |
Systemic signals regulate ageing and rejuvenation of blood stem cell niches. | Mayack SR, Shadrach JL, Kim FS, Wagers AJ | Nature | 20110993 | Nature | 2010 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/20110993 |
Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. | Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT | Cell | 23663781 | Cell | 2013 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/23663781 |
In vivo gene editing in dystrophic mouse muscle and muscle stem cells. | Tabebordbar M, Zhu K, Cheng JKW, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ | Science (New York, N.Y.) | 26721686 | Science | 2016 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/26721686 |
High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice. | Rao TN, Marks-Bluth J, Sullivan J, Gupta MK, Chandrakanthan V, Fitch SR, Ottersbach K, Jang YC, Piao X, Kulkarni RN, Serwold T, Pimanda JE, Wagers AJ | Stem cell research | 25840412 | Stem Cell Res | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25840412 |
Engineering Escherichia coli into a protein delivery system for mammalian cells. | Reeves AZ, Spears WE, Du J, Tan KY, Wagers AJ, Lesser CF | ACS synthetic biology | 25853840 | ACS Synth Biol | 2015 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/25853840 |
Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states. | El Ouaamari A, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qian WJ, Wagers AJ, Kulkarni RN | Cell reports | 23375376 | Cell Rep | 2013 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/23375376 |
Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors. | Rao TN, Gupta MK, Softic S, Wang LD, Jang YC, Thomou T, Bezy O, Kulkarni RN, Kahn CR, Wagers AJ | The EMBO journal | 30446598 | EMBO J | 2018 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/30446598 |
Mutations in Hedgehog pathway genes in fetal rhabdomyomas. | Hettmer S, Teot LA, van Hummelen P, MacConaill L, Bronson RT, Dall'Osso C, Mao J, McMahon AP, Gruber PJ, Grier HE, Rodriguez-Galindo C, Fletcher CD, Wagers AJ | The Journal of pathology | 23780909 | J Pathol | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23780909 |
Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors. | Katsimpardi L, Litterman NK, Schein PA, Miller CM, Loffredo FS, Wojtkiewicz GR, Chen JW, Lee RT, Wagers AJ, Rubin LL | Science (New York, N.Y.) | 24797482 | Science | 2014 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/24797482 |
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle. | Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ | Science (New York, N.Y.) | 24797481 | Science | 2014 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/24797481 |
A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. | Xu C, Tabebordbar M, Iovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Liu M, Barton ER, Kahn CR, Wagers AJ, Zon LI | Cell | 24209627 | Cell | 2013 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/24209627 |
Rejuvenation of regeneration in the aging central nervous system. | Ruckh JM, Zhao JW, Shadrach JL, van Wijngaarden P, Rao TN, Wagers AJ, Franklin RJ | Cell stem cell | 22226359 | Cell Stem Cell | 2012 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/22226359 |
The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation. | Tremblay AM, Missiaglia E, Galli GG, Hettmer S, Urcia R, Carrara M, Judson RN, Thway K, Nadal G, Selfe JL, Murray G, Calogero RA, De Bari C, Zammit PS, Delorenzi M, Wagers AJ, Shipley J, Wackerhage H, Camargo FD | Cancer cell | 25087979 | Cancer Cell | 2014 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/25087979 |
Young, proliferative thymic epithelial cells engraft and function in aging thymuses. | Kim MJ, Miller CM, Shadrach JL, Wagers AJ, Serwold T | Journal of immunology (Baltimore, Md. : 1950) | 25870244 | J Immunol | 2015 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/25870244 |
Graphene-Dielectric Integration for Graphene Transistors. | Liao L, Duan X | Materials science & engineering. R, Reports : a review journal | 21278913 | Mater Sci Eng R Rep | 2010 Nov 22 | https://www.ncbi.nlm.nih.gov/pubmed/21278913 |
High-capacity silicon-air battery in alkaline solution. | Zhong X, Zhang H, Liu Y, Bai J, Liao L, Huang Y, Duan X | ChemSusChem | 22144348 | ChemSusChem | 2012 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/22144348 |
Domain wall motion in synthetic Co2Si nanowires. | Liu G, Lin YC, Liao L, Liu L, Chen Y, Liu Y, Weiss NO, Zhou H, Huang Y, Duan X | Nano letters | 22469009 | Nano Lett | 2012 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/22469009 |
Plasmonic enhancements of photocatalytic activity of Pt/n-Si/Ag photodiodes using Au/Ag core/shell nanorods. | Qu Y, Cheng R, Su Q, Duan X | Journal of the American Chemical Society | 21961900 | J Am Chem Soc | 2011 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/21961900 |
Graphene nanomesh. | Bai J, Zhong X, Jiang S, Huang Y, Duan X | Nature nanotechnology | 20154685 | Nat Nanotechnol | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20154685 |
Rational design and synthesis of freestanding photoelectric nanodevices as highly efficient photocatalysts. | Qu Y, Liao L, Cheng R, Wang Y, Lin YC, Huang Y, Duan X | Nano letters | 20373781 | Nano Lett | 2010 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/20373781 |
Top-gated graphene nanoribbon transistors with ultrathin high-k dielectrics. | Liao L, Bai J, Cheng R, Lin YC, Jiang S, Huang Y, Duan X | Nano letters | 20380441 | Nano Lett | 2010 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/20380441 |
Highly spectral dependent enhancement of upconversion emission with sputtered gold island films. | Zhang H, Xu D, Huang Y, Duan X | Chemical communications (Cambridge, England) | 21079884 | Chem Commun (Camb) | 2011 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/21079884 |
Porous silicon nanowires. | Qu Y, Zhou H, Duan X | Nanoscale | 21869999 | Nanoscale | 2011 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/21869999 |
Plasmonic modulation of the upconversion fluorescence in NaYF4 :Yb/Tm hexaplate nanocrystals using gold nanoparticles or nanoshells. | Zhang H, Li Y, Ivanov IA, Qu Y, Huang Y, Duan X | Angewandte Chemie (International ed. in English) | 20235253 | Angew Chem Int Ed Engl | 2010 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/20235253 |
Sub-100 nm channel length graphene transistors. | Liao L, Bai J, Cheng R, Lin YC, Jiang S, Qu Y, Huang Y, Duan X | Nano letters | 20815334 | Nano Lett | 2010 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/20815334 |
pH-Operated mechanized porous silicon nanoparticles. | Xue M, Zhong X, Shaposhnik Z, Qu Y, Tamanoi F, Duan X, Zink JI | Journal of the American Chemical Society | 21595466 | J Am Chem Soc | 2011 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/21595466 |
Composition tuning the upconversion emission in NaYF4:Yb/Tm hexaplate nanocrystals. | Zhang H, Li Y, Lin Y, Huang Y, Duan X | Nanoscale | 21264435 | Nanoscale | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21264435 |
Electrically conductive and optically active porous silicon nanowires. | Qu Y, Liao L, Li Y, Zhang H, Huang Y, Duan X | Nano letters | 19807130 | Nano Lett | 2009 Dec | https://www.ncbi.nlm.nih.gov/pubmed/19807130 |
High-performance top-gated graphene-nanoribbon transistors using zirconium oxide nanowires as high-dielectric-constant gate dielectrics. | Liao L, Bai J, Lin YC, Qu Y, Huang Y, Duan X | Advanced materials (Deerfield Beach, Fla.) | 20526997 | Adv Mater | 2010 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/20526997 |
Nanoscale morphology, dimensional control, and electrical properties of oligoanilines. | Wang Y, Tran HD, Liao L, Duan X, Kaner RB | Journal of the American Chemical Society | 20662516 | J Am Chem Soc | 2010 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/20662516 |
Unveiling the formation pathway of single crystalline porous silicon nanowires. | Zhong X, Qu Y, Lin YC, Liao L, Duan X | ACS applied materials & interfaces | 21244020 | ACS Appl Mater Interfaces | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/21244020 |
Rational fabrication of graphene nanoribbons using a nanowire etch mask. | Bai J, Duan X, Huang Y | Nano letters | 19344151 | Nano Lett | 2009 May | https://www.ncbi.nlm.nih.gov/pubmed/19344151 |
Very large magnetoresistance in graphene nanoribbons. | Bai J, Cheng R, Xiu F, Liao L, Wang M, Shailos A, Wang KL, Huang Y, Duan X | Nature nanotechnology | 20693988 | Nat Nanotechnol | 2010 Sep | https://www.ncbi.nlm.nih.gov/pubmed/20693988 |
High-speed graphene transistors with a self-aligned nanowire gate. | Liao L, Lin YC, Bao M, Cheng R, Bai J, Liu Y, Qu Y, Wang KL, Huang Y, Duan X | Nature | 20811365 | Nature | 2010 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/20811365 |
Photocatalytic Properties of Porous Silicon Nanowires. | Qu Y, Zhong X, Li Y, Liao L, Huang Y, Duan X | Journal of materials chemistry | 22190767 | J Mater Chem | 2010 | https://www.ncbi.nlm.nih.gov/pubmed/22190767 |
Single-layer graphene on Al2O3/Si substrate: better contrast and higher performance of graphene transistors. | Liao L, Bai J, Qu Y, Huang Y, Duan X | Nanotechnology | 19946170 | Nanotechnology | 2010 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/19946170 |
Heterointegration of Pt/Si/Ag Nanowire Photodiodes and Their Photocatalytic Properties. | Qu Y, Xue T, Zhong X, Lin YC, Liao L, Choi J, Duan X | Advanced functional materials | 21629399 | Adv Funct Mater | 2010 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/21629399 |
Toward tunable band gap and tunable dirac point in bilayer graphene with molecular doping. | Yu WJ, Liao L, Chae SH, Lee YH, Duan X | Nano letters | 21985035 | Nano Lett | 2011 Nov 9 | https://www.ncbi.nlm.nih.gov/pubmed/21985035 |
High-kappa oxide nanoribbons as gate dielectrics for high mobility top-gated graphene transistors. | Liao L, Bai J, Qu Y, Lin YC, Li Y, Huang Y, Duan X | Proceedings of the National Academy of Sciences of the United States of America | 20308584 | Proc Natl Acad Sci U S A | 2010 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/20308584 |
Patient-to-patient variability in autologous pericardial matrix scaffolds for cardiac repair. | Seif-Naraghi SB, Horn D, Schup-Magoffin PA, Madani MM, Christman KL | Journal of cardiovascular translational research | 21695575 | J Cardiovasc Transl Res | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21695575 |
Modulation of material properties of a decellularized myocardial matrix scaffold. | Singelyn JM, Christman KL | Macromolecular bioscience | 21322109 | Macromol Biosci | 2011 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/21322109 |
Award winner for outstanding research in the PhD category, 2014 Society for Biomaterials annual meeting and exposition, Denver, Colorado, April 16-19, 2014: Decellularized adipose matrix hydrogels stimulate in vivo neovascularization and adipose formation. | Adam Young D, Bajaj V, Christman KL | Journal of biomedical materials research. Part A | 24510423 | J Biomed Mater Res A | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24510423 |
Injectable extracellular matrix derived hydrogel provides a platform for enhanced retention and delivery of a heparin-binding growth factor. | Seif-Naraghi SB, Horn D, Schup-Magoffin PJ, Christman KL | Acta biomaterialia | 22750737 | Acta Biomater | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22750737 |
Tailoring material properties of a nanofibrous extracellular matrix derived hydrogel. | Johnson TD, Lin SY, Christman KL | Nanotechnology | 22101810 | Nanotechnology | 2011 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/22101810 |
NANOPATTERNED INTERFACES FOR CONTROLLING CELL BEHAVIOR. | Chung K, DeQUACH JA, Christman KL | Nano LIFE | 25383101 | Nano Life | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25383101 |
Design and characterization of an injectable pericardial matrix gel: a potentially autologous scaffold for cardiac tissue engineering. | Seif-Naraghi SB, Salvatore MA, Schup-Magoffin PJ, Hu DP, Christman KL | Tissue engineering. Part A | 20100033 | Tissue Eng Part A | 2010 Jun | https://www.ncbi.nlm.nih.gov/pubmed/20100033 |
Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering. | Singelyn JM, DeQuach JA, Seif-Naraghi SB, Littlefield RB, Schup-Magoffin PJ, Christman KL | Biomaterials | 19608268 | Biomaterials | 2009 Oct | https://www.ncbi.nlm.nih.gov/pubmed/19608268 |
Surface patterning for generating defined nanoscale matrices. | Christman KL, Maynard HD | Methods in molecular biology (Clifton, N.J.) | 20680824 | Methods Mol Biol | 2010 | https://www.ncbi.nlm.nih.gov/pubmed/20680824 |
Injectable materials for the treatment of myocardial infarction and heart failure: the promise of decellularized matrices. | Singelyn JM, Christman KL | Journal of cardiovascular translational research | 20632221 | J Cardiovasc Transl Res | 2010 Oct | https://www.ncbi.nlm.nih.gov/pubmed/20632221 |
Fabrication of biologically derived injectable materials for myocardial tissue engineering. | Seif-Naraghi S, Singelyn J, Dequach J, Schup-Magoffin P, Christman K | Journal of visualized experiments : JoVE | 22158083 | J Vis Exp | 2010 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/22158083 |
Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction. | Rane AA, Chuang JS, Shah A, Hu DP, Dalton ND, Gu Y, Peterson KL, Omens JH, Christman KL | PloS one | 21731777 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/21731777 |
Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds. | DeQuach JA, Yuan SH, Goldstein LS, Christman KL | Tissue engineering. Part A | 21883047 | Tissue Eng Part A | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21883047 |
Antibacterial and cell-adhesive polypeptide and poly(ethylene glycol) hydrogel as a potential scaffold for wound healing. | Song A, Rane AA, Christman KL | Acta biomaterialia | 22023748 | Acta Biomater | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22023748 |
Fibroblasts influence muscle progenitor differentiation and alignment in contact independent and dependent manners in organized co-culture devices. | Rao N, Evans S, Stewart D, Spencer KH, Sheikh F, Hui EE, Christman KL | Biomedical microdevices | 22983793 | Biomed Microdevices | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/22983793 |
Human cardiomyogenesis and the need for systems biology analysis. | Young DA, DeQuach JA, Christman KL | Wiley interdisciplinary reviews. Systems biology and medicine | 21197666 | Wiley Interdiscip Rev Syst Biol Med | 2011 Nov-Dec | https://www.ncbi.nlm.nih.gov/pubmed/21197666 |
Catheter-deliverable hydrogel derived from decellularized ventricular extracellular matrix increases endogenous cardiomyocytes and preserves cardiac function post-myocardial infarction. | Singelyn JM, Sundaramurthy P, Johnson TD, Schup-Magoffin PJ, Hu DP, Faulk DM, Wang J, Mayle KM, Bartels K, Salvatore M, Kinsey AM, Demaria AN, Dib N, Christman KL | Journal of the American College of Cardiology | 22340268 | J Am Coll Cardiol | 2012 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/22340268 |
Oxime cross-linked injectable hydrogels for catheter delivery. | Grover GN, Braden RL, Christman KL | Advanced materials (Deerfield Beach, Fla.) | 23495015 | Adv Mater | 2013 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/23495015 |
Injectable skeletal muscle matrix hydrogel promotes neovascularization and muscle cell infiltration in a hindlimb ischemia model. | DeQuach JA, Lin JE, Cam C, Hu D, Salvatore MA, Sheikh F, Christman KL | European cells & materials | 22665162 | Eur Cell Mater | 2012 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/22665162 |
Injectable biomaterials for adipose tissue engineering. | Young DA, Christman KL | Biomedical materials (Bristol, England) | 22456805 | Biomed Mater | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22456805 |
Injectable hydrogel scaffold from decellularized human lipoaspirate. | Young DA, Ibrahim DO, Hu D, Christman KL | Acta biomaterialia | 20932943 | Acta Biomater | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20932943 |
Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture. | DeQuach JA, Mezzano V, Miglani A, Lange S, Keller GM, Sheikh F, Christman KL | PloS one | 20885963 | PLoS One | 2010 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/20885963 |
Cytoplasmic dynein is required for the spatial organization of protein aggregates in filamentous fungi. | Egan MJ, McClintock MA, Hollyer IH, Elliott HL, Reck-Peterson SL | Cell reports | 25865884 | Cell Rep | 2015 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/25865884 |
A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity. | Tan K, Roberts AJ, Chonofsky M, Egan MJ, Reck-Peterson SL | Molecular biology of the cell | 24403603 | Mol Biol Cell | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24403603 |
Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters. | Laan L, Pavin N, Husson J, Romet-Lemonne G, van Duijn M, López MP, Vale RD, Jülicher F, Reck-Peterson SL, Dogterom M | Cell | 22304918 | Cell | 2012 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/22304918 |
Engineered, harnessed, and hijacked: synthetic uses for cytoskeletal systems. | Goodman BS, Derr ND, Reck-Peterson SL | Trends in cell biology | 23059001 | Trends Cell Biol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23059001 |
Microtubule-based transport in filamentous fungi. | Egan MJ, McClintock MA, Reck-Peterson SL | Current opinion in microbiology | 23127389 | Curr Opin Microbiol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23127389 |
Aspergillus myosin-V supports polarized growth in the absence of microtubule-based transport. | Zhang J, Tan K, Wu X, Chen G, Sun J, Reck-Peterson SL, Hammer JA 3rd, Xiang X | PloS one | 22194856 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22194856 |
Structural basis for microtubule binding and release by dynein. | Redwine WB, Hernandez-Lopez R, Zou S, Huang J, Reck-Peterson SL, Leschziner AE | Science (New York, N.Y.) | 22997337 | Science | 2012 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/22997337 |
Lis1 is an initiation factor for dynein-driven organelle transport. | Egan MJ, Tan K, Reck-Peterson SL | The Journal of cell biology | 22711696 | J Cell Biol | 2012 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/22711696 |
Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor. | Huang J, Roberts AJ, Leschziner AE, Reck-Peterson SL | Cell | 22939623 | Cell | 2012 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/22939623 |
Characterization of the mutagenic spectrum of 4-nitroquinoline 1-oxide (4-NQO) in Aspergillus nidulans by whole genome sequencing. | Downes DJ, Chonofsky M, Tan K, Pfannenstiel BT, Reck-Peterson SL, Todd RB | G3 (Bethesda, Md.) | 25352541 | G3 (Bethesda) | 2014 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/25352541 |
Dynein achieves processive motion using both stochastic and coordinated stepping. | Qiu W, Derr ND, Goodman BS, Villa E, Wu D, Shih W, Reck-Peterson SL | Nature structural & molecular biology | 22231401 | Nat Struct Mol Biol | 2012 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/22231401 |
Peroxisomes move by hitchhiking on early endosomes using the novel linker protein PxdA. | Salogiannis J, Egan MJ, Reck-Peterson SL | The Journal of cell biology | 26811422 | J Cell Biol | 2016 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/26811422 |
GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding. | Dippold HC, Ng MM, Farber-Katz SE, Lee SK, Kerr ML, Peterman MC, Sim R, Wiharto PA, Galbraith KA, Madhavarapu S, Fuchs GJ, Meerloo T, Farquhar MG, Zhou H, Field SJ | Cell | 19837035 | Cell | 2009 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/19837035 |
Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation. | Nhek S, Ngo M, Yang X, Ng MM, Field SJ, Asara JM, Ridgway ND, Toker A | Molecular biology of the cell | 20444975 | Mol Biol Cell | 2010 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/20444975 |
GOLPH3 links the Golgi, DNA damage, and cancer. | Buschman MD, Rahajeng J, Field SJ | Cancer research | 25634214 | Cancer Res | 2015 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/25634214 |
Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression. | Schmid MC, Avraamides CJ, Dippold HC, Franco I, Foubert P, Ellies LG, Acevedo LM, Manglicmot JR, Song X, Wrasidlo W, Blair SL, Ginsberg MH, Cheresh DA, Hirsch E, Field SJ, Varner JA | Cancer cell | 21665146 | Cancer Cell | 2011 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/21665146 |
Role of phosphatidylinositol 4-phosphate (PI4P) and its binding protein GOLPH3 in hepatitis C virus secretion. | Bishé B, Syed GH, Field SJ, Siddiqui A | The Journal of biological chemistry | 22745132 | J Biol Chem | 2012 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/22745132 |
Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies. | Bielas SL, Silhavy JL, Brancati F, Kisseleva MV, Al-Gazali L, Sztriha L, Bayoumi RA, Zaki MS, Abdel-Aleem A, Rosti RO, Kayserili H, Swistun D, Scott LC, Bertini E, Boltshauser E, Fazzi E, Travaglini L, Field SJ, Gayral S, Jacoby M, Schurmans S, Dallapiccola B, Majerus PW, Valente EM, Gleeson JG | Nature genetics | 19668216 | Nat Genet | 2009 Sep | https://www.ncbi.nlm.nih.gov/pubmed/19668216 |
GOLPH3L antagonizes GOLPH3 to determine Golgi morphology. | Ng MM, Dippold HC, Buschman MD, Noakes CJ, Field SJ | Molecular biology of the cell | 23345592 | Mol Biol Cell | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23345592 |
Regulation of Drosophila mesoderm migration by phosphoinositides and the PH domain of the Rho GTP exchange factor Pebble. | Murray MJ, Ng MM, Fraval H, Tan J, Liu W, Smallhorn M, Brill JA, Field SJ, Saint R | Developmental biology | 23000359 | Dev Biol | 2012 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/23000359 |
DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3. | Farber-Katz SE, Dippold HC, Buschman MD, Peterman MC, Xing M, Noakes CJ, Tat J, Ng MM, Rahajeng J, Cowan DM, Fuchs GJ, Zhou H, Field SJ | Cell | 24485452 | Cell | 2014 Jan 30 | https://www.ncbi.nlm.nih.gov/pubmed/24485452 |
Electrochemical measurement of endogenous serotonin release from human blood platelets. | Ge S, Woo E, White JG, Haynes CL | Analytical chemistry | 21384903 | Anal Chem | 2011 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/21384903 |
Critical role of membrane cholesterol in exocytosis revealed by single platelet study. | Ge S, White JG, Haynes CL | ACS chemical biology | 20590163 | ACS Chem Biol | 2010 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/20590163 |
Checkpoints for Preliminary Identification of Small Molecules found Enriched in Autophagosomes and Activated Mast Cell Secretions Analyzed by Comparative UPLC/MS(e). | Satori CP, Ramezani M, Koopmeiners JS, Meyer AF, Rodriguez-Navarro JA, Kuhns MM, Taylor TH, Haynes CL, Dalluge JJ, Arriaga EA | Analytical methods : advancing methods and applications | 28194233 | Anal Methods | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28194233 |
Exploring inflammatory disease drug effects on neutrophil function. | Wu X, Kim D, Young AT, Haynes CL | The Analyst | 24946254 | Analyst | 2014 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/24946254 |
Cytoskeleton dynamics in drug-treated platelets. | Finkenstaedt-Quinn SA, Ge S, Haynes CL | Analytical and bioanalytical chemistry | 25701419 | Anal Bioanal Chem | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25701419 |
Electroanalytical eavesdropping on single cell communication. | Kim D, Koseoglu S, Manning BM, Meyer AF, Haynes CL | Analytical chemistry | 21766792 | Anal Chem | 2011 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/21766792 |
On-chip evaluation of platelet adhesion and aggregation upon exposure to mesoporous silica nanoparticles. | Kim D, Finkenstaedt-Quinn S, Hurley KR, Buchman JT, Haynes CL | The Analyst | 24300894 | Analyst | 2014 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/24300894 |
The role of p38 MAPK in neutrophil functions: single cell chemotaxis and surface marker expression. | Kim D, Haynes CL | The Analyst | 24061073 | Analyst | 2013 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/24061073 |
Analytical characterization of the role of phospholipids in platelet adhesion and secretion. | Koseoglu S, Meyer AF, Kim D, Meyer BM, Wang Y, Dalluge JJ, Haynes CL | Analytical chemistry | 25439269 | Anal Chem | 2015 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/25439269 |
Time- and concentration-dependent effects of exogenous serotonin and inflammatory cytokines on mast cell function. | Gruba SM, Meyer AF, Manning BM, Wang Y, Thompson JW, Dalluge JJ, Haynes CL | ACS chemical biology | 24304209 | ACS Chem Biol | 2014 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/24304209 |
Microfluidics-based in vivo mimetic systems for the study of cellular biology. | Kim D, Wu X, Young AT, Haynes CL | Accounts of chemical research | 24555566 | Acc Chem Res | 2014 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/24555566 |
Platelet membrane variations and their effects on δ-granule secretion kinetics and aggregation spreading among different species. | Gruba SM, Koseoglu S, Meyer AF, Meyer BM, Maurer-Jones MA, Haynes CL | Biochimica et biophysica acta | 25906946 | Biochim Biophys Acta | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25906946 |
Carbon-fiber microelectrode amperometry reveals sickle-cell-induced inflammation and chronic morphine effects on single mast cells. | Manning BM, Hebbel RP, Gupta K, Haynes CL | ACS chemical biology | 22217155 | ACS Chem Biol | 2012 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/22217155 |
Cytoskeletal F-actin, not the circumferential coil of microtubules, regulates platelet dense-body granule secretion. | Ge S, White JG, Haynes CL | Platelets | 21988315 | Platelets | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/21988315 |
Recent progress in SERS biosensing. | Bantz KC, Meyer AF, Wittenberg NJ, Im H, Kurtuluş O, Lee SH, Lindquist NC, Oh SH, Haynes CL | Physical chemistry chemical physics : PCCP | 21509385 | Phys Chem Chem Phys | 2011 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/21509385 |
Dynamin-related protein-1 controls fusion pore dynamics during platelet granule exocytosis. | Koseoglu S, Dilks JR, Peters CG, Fitch-Tewfik JL, Fadel NA, Jasuja R, Italiano JE Jr, Haynes CL, Flaumenhaft R | Arteriosclerosis, thrombosis, and vascular biology | 23288151 | Arterioscler Thromb Vasc Biol | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23288151 |
Neutrophil chemotaxis within a competing gradient of chemoattractants. | Kim D, Haynes CL | Analytical chemistry | 22816782 | Anal Chem | 2012 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/22816782 |
On-chip evaluation of neutrophil activation and neutrophil-endothelial cell interaction during neutrophil chemotaxis. | Kim D, Haynes CL | Analytical chemistry | 24127752 | Anal Chem | 2013 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/24127752 |
Neuropeptide-Induced Mast Cell Degranulation and Characterization of Signaling Modulation in Response to IgE Conditioning. | Manning BM, Gruba SM, Meyer AF, Haynes CL | ACS chemical biology | 27580075 | ACS Chem Biol | 2016 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/27580075 |
Microfluidic-SERS devices for one shot limit-of-detection. | Kim D, Campos AR, Datt A, Gao Z, Rycenga M, Burrows ND, Greeneltch NG, Mirkin CA, Murphy CJ, Van Duyne RP, Haynes CL | The Analyst | 24756225 | Analyst | 2014 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/24756225 |
On-chip evaluation of shear stress effect on cytotoxicity of mesoporous silica nanoparticles. | Kim D, Lin YS, Haynes CL | Analytical chemistry | 22032307 | Anal Chem | 2011 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/22032307 |
Single-cell analysis of mast cell degranulation induced by airway smooth muscle-secreted chemokines. | Manning BM, Meyer AF, Gruba SM, Haynes CL | Biochimica et biophysica acta | 25986989 | Biochim Biophys Acta | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25986989 |
Variations in Fusion Pore Formation in Cholesterol-Treated Platelets. | Finkenstaedt-Quinn SA, Gruba SM, Haynes CL | Biophysical journal | 26910428 | Biophys J | 2016 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/26910428 |
Platelet Response to Allergens, CXCL10, and CXCL5 in the Context of Asthma. | Gruba S, Wu X, Spanolios E, He J, Xiong-Hang K, Haynes CL | ACS bio & med chem Au | 36820311 | ACS Bio Med Chem Au | 2023 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/36820311 |
Bacterial capsular polysaccharide prevents the onset of asthma through T-cell activation. | Johnson JL, Jones MB, Cobb BA | Glycobiology | 25347992 | Glycobiology | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25347992 |
Infection, inflammation and host carbohydrates: a Glyco-Evasion Hypothesis. | Kreisman LS, Cobb BA | Glycobiology | 22492234 | Glycobiology | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22492234 |
Carbohydrate oxidation acidifies endosomes, regulating antigen processing and TLR9 signaling. | Lewis CJ, Cobb BA | Journal of immunology (Baltimore, Md. : 1950) | 20200279 | J Immunol | 2010 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/20200279 |
Host glycans and antigen presentation. | Ryan SO, Cobb BA | Microbes and infection | 22580092 | Microbes Infect | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22580092 |
B-cell-independent sialylation of IgG. | Jones MB, Oswald DM, Joshi S, Whiteheart SW, Orlando R, Cobb BA | Proceedings of the National Academy of Sciences of the United States of America | 27303031 | Proc Natl Acad Sci U S A | 2016 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/27303031 |
Roles for major histocompatibility complex glycosylation in immune function. | Ryan SO, Cobb BA | Seminars in immunopathology | 22461020 | Semin Immunopathol | 2012 May | https://www.ncbi.nlm.nih.gov/pubmed/22461020 |
MHCII glycosylation modulates Bacteroides fragilis carbohydrate antigen presentation. | Ryan SO, Bonomo JA, Zhao F, Cobb BA | The Journal of experimental medicine | 21502329 | J Exp Med | 2011 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/21502329 |
Type I Streptococcus pneumoniae carbohydrate utilizes a nitric oxide and MHC II-dependent pathway for antigen presentation. | Velez CD, Lewis CJ, Kasper DL, Cobb BA | Immunology | 18778282 | Immunology | 2009 May | https://www.ncbi.nlm.nih.gov/pubmed/18778282 |
The regulatory power of glycans and their binding partners in immunity. | Johnson JL, Jones MB, Ryan SO, Cobb BA | Trends in immunology | 23485517 | Trends Immunol | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23485517 |
Polysaccharide A from the capsule of Bacteroides fragilis induces clonal CD4+ T cell expansion. | Johnson JL, Jones MB, Cobb BA | The Journal of biological chemistry | 25540199 | J Biol Chem | 2015 Feb 20 | https://www.ncbi.nlm.nih.gov/pubmed/25540199 |
Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses. | Ryan SO, Leal SM Jr, Abbott DW, Pearlman E, Cobb BA | Glycobiology | 24310166 | Glycobiology | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24310166 |
Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells. | Bloem K, García-Vallejo JJ, Vuist IM, Cobb BA, van Vliet SJ, van Kooyk Y | Frontiers in immunology | 23653626 | Front Immunol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23653626 |
Glycoantigens induce human peripheral Tr1 cell differentiation with gut-homing specialization. | Kreisman LS, Cobb BA | The Journal of biological chemistry | 21228275 | J Biol Chem | 2011 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/21228275 |
Structural characterization and MHCII-dependent immunological properties of the zwitterionic O-chain antigen of Morganella morganii. | Young NM, Kreisman LS, Stupak J, MacLean LL, Cobb BA, Richards JC | Glycobiology | 21321054 | Glycobiology | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21321054 |
Glycobiology of immune responses. | Rabinovich GA, van Kooyk Y, Cobb BA | Annals of the New York Academy of Sciences | 22524422 | Ann N Y Acad Sci | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22524422 |
Neutrophils confer T cell resistance to myeloid-derived suppressor cell-mediated suppression to promote chronic inflammation. | Ryan SO, Johnson JL, Cobb BA | Journal of immunology (Baltimore, Md. : 1950) | 23576679 | J Immunol | 2013 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/23576679 |
Mycobacterium tuberculosis synergizes with ATP to induce release of microvesicles and exosomes containing major histocompatibility complex class II molecules capable of antigen presentation. | Ramachandra L, Qu Y, Wang Y, Lewis CJ, Cobb BA, Takatsu K, Boom WH, Dubyak GR, Harding CV | Infection and immunity | 20837713 | Infect Immun | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/20837713 |
Myeloid glycosylation defects lead to a spontaneous common variable immunodeficiency-like condition with associated hemolytic anemia and antilymphocyte autoimmunity. | Ryan SO, Abbott DW, Cobb BA | Journal of immunology (Baltimore, Md. : 1950) | 24795453 | J Immunol | 2014 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/24795453 |
Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production. | Lewis CJ, Cobb BA | European journal of immunology | 21630251 | Eur J Immunol | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21630251 |
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness. | Pathak A, Kumar S | Integrative biology : quantitative biosciences from nano to macro | 21210057 | Integr Biol (Camb) | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21210057 |
Biophysics and dynamics of natural and engineered stem cell microenvironments. | Keung AJ, Healy KE, Kumar S, Schaffer DV | Wiley interdisciplinary reviews. Systems biology and medicine | 20836010 | Wiley Interdiscip Rev Syst Biol Med | 2010 Jan-Feb | https://www.ncbi.nlm.nih.gov/pubmed/20836010 |
Cell-Matrix De-Adhesion Dynamics Reflect Contractile Mechanics. | Sen S, Kumar S | Cellular and molecular bioengineering | 21297858 | Cell Mol Bioeng | 2009 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21297858 |
Combining mechanical and optical approaches to dissect cellular mechanobiology. | Sen S, Kumar S | Journal of biomechanics | 19819457 | J Biomech | 2010 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/19819457 |
Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression. | Lam WA, Cao L, Umesh V, Keung AJ, Sen S, Kumar S | Molecular cancer | 20144241 | Mol Cancer | 2010 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/20144241 |
Cell-matrix mechanobiology: applications to brain tumors and design of tissue engineering scaffolds. | Kumar S | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19964076 | Annu Int Conf IEEE Eng Med Biol Soc | 2009 | https://www.ncbi.nlm.nih.gov/pubmed/19964076 |
The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. | Ulrich TA, de Juan Pardo EM, Kumar S | Cancer research | 19435897 | Cancer Res | 2009 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/19435897 |
A fluorescent peroxidase probe increases the sensitivity of commercial ELISAs by two orders of magnitude. | Acharya AP, Nafisi PM, Gardner A, Mackay JL, Kundu K, Kumar S, Murthy N | Chemical communications (Cambridge, England) | 24071916 | Chem Commun (Camb) | 2013 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/24071916 |
Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform. | Ananthanarayanan B, Kim Y, Kumar S | Biomaterials | 21820737 | Biomaterials | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21820737 |
Independent regulation of tumor cell migration by matrix stiffness and confinement. | Pathak A, Kumar S | Proceedings of the National Academy of Sciences of the United States of America | 22689955 | Proc Natl Acad Sci U S A | 2012 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/22689955 |
Rho GTPases mediate the mechanosensitive lineage commitment of neural stem cells. | Keung AJ, de Juan-Pardo EM, Schaffer DV, Kumar S | Stem cells (Dayton, Ohio) | 21956892 | Stem Cells | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21956892 |
From molecular signal activation to locomotion: an integrated, multiscale analysis of cell motility on defined matrices. | Pathak A, Kumar S | PloS one | 21483802 | PLoS One | 2011 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/21483802 |
A composite hydrogel platform for the dissection of tumor cell migration at tissue interfaces. | Rape AD, Kumar S | Biomaterials | 25047626 | Biomaterials | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25047626 |
Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve. | Gould RA, Yalcin HC, MacKay JL, Sauls K, Norris R, Kumar S, Butcher JT | Current biology : CB | 26725196 | Curr Biol | 2016 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/26725196 |
Vinculin tension distributions of individual stress fibers within cell-matrix adhesions. | Chang CW, Kumar S | Journal of cell science | 23687380 | J Cell Sci | 2013 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/23687380 |
Microenvironmental stiffness enhances glioma cell proliferation by stimulating epidermal growth factor receptor signaling. | Umesh V, Rape AD, Ulrich TA, Kumar S | PloS one | 25000176 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25000176 |
Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells. | Keung AJ, Asuri P, Kumar S, Schaffer DV | Integrative biology : quantitative biosciences from nano to macro | 22854634 | Integr Biol (Camb) | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22854634 |
Measuring the elastic properties of living cells with atomic force microscopy indentation. | Mackay JL, Kumar S | Methods in molecular biology (Clifton, N.J.) | 23027009 | Methods Mol Biol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23027009 |
Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters. | MacKay JL, Kumar S | Integrative biology : quantitative biosciences from nano to macro | 25044255 | Integr Biol (Camb) | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25044255 |
Probing cellular mechanobiology in three-dimensional culture with collagen-agarose matrices. | Ulrich TA, Jain A, Tanner K, MacKay JL, Kumar S | Biomaterials | 19926126 | Biomaterials | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/19926126 |
Mechanics, malignancy, and metastasis: the force journey of a tumor cell. | Kumar S, Weaver VM | Cancer metastasis reviews | 19153673 | Cancer Metastasis Rev | 2009 Jun | https://www.ncbi.nlm.nih.gov/pubmed/19153673 |
Contributions of talin-1 to glioma cell-matrix tensional homeostasis. | Sen S, Ng WP, Kumar S | Journal of the Royal Society, Interface | 22158841 | J R Soc Interface | 2012 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/22158841 |
Microtopographical assembly of cardiomyocytes. | Patel AA, Desai TA, Kumar S | Integrative biology : quantitative biosciences from nano to macro | 21863181 | Integr Biol (Camb) | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21863181 |
Microscale mechanisms of agarose-induced disruption of collagen remodeling. | Ulrich TA, Lee TG, Shon HK, Moon DW, Kumar S | Biomaterials | 21575987 | Biomaterials | 2011 Aug | https://www.ncbi.nlm.nih.gov/pubmed/21575987 |
Dissecting regional variations in stress fiber mechanics in living cells with laser nanosurgery. | Tanner K, Boudreau A, Bissell MJ, Kumar S | Biophysical journal | 21044574 | Biophys J | 2010 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/21044574 |
Pan-neuronal maturation but not neuronal subtype differentiation of adult neural stem cells is mechanosensitive. | Keung AJ, Dong M, Schaffer DV, Kumar S | Scientific reports | 23660869 | Sci Rep | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23660869 |
Differential Contributions of Nonmuscle Myosin II Isoforms and Functional Domains to Stress Fiber Mechanics. | Chang CW, Kumar S | Scientific reports | 26336830 | Sci Rep | 2015 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/26336830 |
Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration. | Pathak A, Kumar S | Integrative biology : quantitative biosciences from nano to macro | 23832051 | Integr Biol (Camb) | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23832051 |
Contractility dominates adhesive ligand density in regulating cellular de-adhesion and retraction kinetics. | Sen S, Ng WP, Kumar S | Annals of biomedical engineering | 21046466 | Ann Biomed Eng | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21046466 |
Three-dimensional patterning of multiple cell populations through orthogonal genetic control of cell motility. | MacKay JL, Sood A, Kumar S | Soft matter | 24622945 | Soft Matter | 2014 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/24622945 |
A genetic strategy for the dynamic and graded control of cell mechanics, motility, and matrix remodeling. | MacKay JL, Keung AJ, Kumar S | Biophysical journal | 22325265 | Biophys J | 2012 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/22325265 |
CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility. | Kim Y, Kumar S | Molecular cancer research : MCR | 24962319 | Mol Cancer Res | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24962319 |
Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology. | Sen S, Dong M, Kumar S | PloS one | 20037648 | PLoS One | 2009 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/20037648 |
Modulating malignant epithelial tumor cell adhesion, migration and mechanics with nanorod surfaces. | Lee J, Chu BH, Sen S, Gupte A, Chancellor TJ, Chang CY, Ren F, Kumar S, Lele TP | Biomedical microdevices | 20830527 | Biomed Microdevices | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/20830527 |
Presentation counts: microenvironmental regulation of stem cells by biophysical and material cues. | Keung AJ, Kumar S, Schaffer DV | Annual review of cell and developmental biology | 20590452 | Annu Rev Cell Dev Biol | 2010 | https://www.ncbi.nlm.nih.gov/pubmed/20590452 |
Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion. | Wong SY, Ulrich TA, Deleyrolle LP, MacKay JL, Lin JM, Martuscello RT, Jundi MA, Reynolds BA, Kumar S | Cancer research | 25634210 | Cancer Res | 2015 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/25634210 |
Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival. | Silva IA, Bai S, McLean K, Yang K, Griffith K, Thomas D, Ginestier C, Johnston C, Kueck A, Reynolds RK, Wicha MS, Buckanovich RJ | Cancer research | 21498635 | Cancer Res | 2011 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/21498635 |
EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells. | Bai S, Ingram P, Chen YC, Deng N, Pearson A, Niknafs YS, O'Hayer P, Wang Y, Zhang ZY, Boscolo E, Bischoff J, Yoon E, Buckanovich RJ | Cancer research | 27803106 | Cancer Res | 2016 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/27803106 |
Ovarian cancer stem cell markers: prognostic and therapeutic implications. | Burgos-Ojeda D, Rueda BR, Buckanovich RJ | Cancer letters | 22334034 | Cancer Lett | 2012 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/22334034 |
A novel model for evaluating therapies targeting human tumor vasculature and human cancer stem-like cells. | Burgos-Ojeda D, McLean K, Bai S, Pulaski H, Gong Y, Silva I, Skorecki K, Tzukerman M, Buckanovich RJ | Cancer research | 23576551 | Cancer Res | 2013 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/23576551 |
Metformin targets ovarian cancer stem cells in vitro and in vivo. | Shank JJ, Yang K, Ghannam J, Cabrera L, Johnston CJ, Reynolds RK, Buckanovich RJ | Gynecologic oncology | 22864111 | Gynecol Oncol | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/22864111 |
F3-targeted cisplatin-hydrogel nanoparticles as an effective therapeutic that targets both murine and human ovarian tumor endothelial cells in vivo. | Winer I, Wang S, Lee YE, Fan W, Gong Y, Burgos-Ojeda D, Spahlinger G, Kopelman R, Buckanovich RJ | Cancer research | 20959470 | Cancer Res | 2010 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/20959470 |
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. | Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K | Cell stem cell | 18371336 | Cell Stem Cell | 2007 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/18371336 |
Chromatin connections to pluripotency and cellular reprogramming. | Orkin SH, Hochedlinger K | Cell | 21663790 | Cell | 2011 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/21663790 |
Modeling Rett syndrome with stem cells. | Walsh RM, Hochedlinger K | Cell | 21074040 | Cell | 2010 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/21074040 |
The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. | Sarkar A, Hochedlinger K | Cell stem cell | 23290134 | Cell Stem Cell | 2013 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/23290134 |
A reprogrammable mouse strain from gene-targeted embryonic stem cells. | Stadtfeld M, Maherali N, Borkent M, Hochedlinger K | Nature methods | 20010832 | Nat Methods | 2010 Jan | https://www.ncbi.nlm.nih.gov/pubmed/20010832 |
Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium. | Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y | Development (Cambridge, England) | 23222438 | Development | 2013 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/23222438 |
Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice. | Arnold K, Sarkar A, Yram MA, Polo JM, Bronson R, Sengupta S, Seandel M, Geijsen N, Hochedlinger K | Cell stem cell | 21982232 | Cell Stem Cell | 2011 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/21982232 |
Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc. | Maherali N, Hochedlinger K | Current biology : CB | 19765992 | Curr Biol | 2009 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/19765992 |
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. | Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, Natesan S, Kono T, Shioda T, Hochedlinger K | Nature | 20418860 | Nature | 2010 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/20418860 |
Induced pluripotent stem cells generated without viral integration. | Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K | Science (New York, N.Y.) | 18818365 | Science | 2008 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/18818365 |
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. | Stadtfeld M, Maherali N, Breault DT, Hochedlinger K | Cell stem cell | 18371448 | Cell Stem Cell | 2008 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/18371448 |
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. | Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, Walsh RM, Khalil A, Rheinwald JG, Hochedlinger K | Nature | 19668190 | Nature | 2009 Aug 27 | https://www.ncbi.nlm.nih.gov/pubmed/19668190 |
A high-efficiency system for the generation and study of human induced pluripotent stem cells. | Maherali N, Ahfeldt T, Rigamonti A, Utikal J, Cowan C, Hochedlinger K | Cell stem cell | 18786420 | Cell Stem Cell | 2008 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/18786420 |
Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. | Eminli S, Foudi A, Stadtfeld M, Maherali N, Ahfeldt T, Mostoslavsky G, Hock H, Hochedlinger K | Nature genetics | 19668214 | Nat Genet | 2009 Sep | https://www.ncbi.nlm.nih.gov/pubmed/19668214 |
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. | Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, Mostoslavsky G | Stem cells (Dayton, Ohio) | 19096035 | Stem Cells | 2009 Mar | https://www.ncbi.nlm.nih.gov/pubmed/19096035 |
Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming. | Apostolou E, Ferrari F, Walsh RM, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart HT, Polo JM, Ohsumi TK, Borowsky ML, Kharchenko PV, Park PJ, Hochedlinger K | Cell stem cell | 23665121 | Cell Stem Cell | 2013 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/23665121 |
Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. | Stadtfeld M, Apostolou E, Ferrari F, Choi J, Walsh RM, Chen T, Ooi SS, Kim SY, Bestor TH, Shioda T, Park PJ, Hochedlinger K | Nature genetics | 22387999 | Nat Genet | 2012 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/22387999 |
A molecular roadmap of reprogramming somatic cells into iPS cells. | Polo JM, Anderssen E, Walsh RM, Schwarz BA, Nefzger CM, Lim SM, Borkent M, Apostolou E, Alaei S, Cloutier J, Bar-Nur O, Cheloufi S, Stadtfeld M, Figueroa ME, Robinton D, Natesan S, Melnick A, Zhu J, Ramaswamy S, Hochedlinger K | Cell | 23260147 | Cell | 2012 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/23260147 |
Reprogramming of pancreatic beta cells into induced pluripotent stem cells. | Stadtfeld M, Brennand K, Hochedlinger K | Current biology : CB | 18501604 | Curr Biol | 2008 Jun 24 | https://www.ncbi.nlm.nih.gov/pubmed/18501604 |
Efficient generation of iPS cells from skeletal muscle stem cells. | Tan KY, Eminli S, Hettmer S, Hochedlinger K, Wagers AJ | PloS one | 22028872 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22028872 |
Isolevuglandin-modified phosphatidylethanolamine is metabolized by NAPE-hydrolyzing phospholipase D. | Guo L, Gragg SD, Chen Z, Zhang Y, Amarnath V, Davies SS | Journal of lipid research | 24018423 | J Lipid Res | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24018423 |
F2-isoprostanes as an indicator and risk factor for coronary heart disease. | Davies SS, Roberts LJ 2nd | Free radical biology & medicine | 21126576 | Free Radic Biol Med | 2011 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/21126576 |
A liquid chromatography-tandem mass spectrometry method for measurement of N-modified phosphatidylethanolamines. | Guo L, Amarnath V, Davies SS | Analytical biochemistry | 20599652 | Anal Biochem | 2010 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/20599652 |
Incorporation of therapeutically modified bacteria into gut microbiota inhibits obesity. | Chen Z, Guo L, Zhang Y, Walzem RL, Pendergast JS, Printz RL, Morris LC, Matafonova E, Stien X, Kang L, Coulon D, McGuinness OP, Niswender KD, Davies SS | The Journal of clinical investigation | 24960158 | J Clin Invest | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24960158 |
Identification of novel bioactive aldehyde-modified phosphatidylethanolamines formed by lipid peroxidation. | Guo L, Chen Z, Amarnath V, Davies SS | Free radical biology & medicine | 22898174 | Free Radic Biol Med | 2012 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/22898174 |
Phosphatidylethanolamines modified by γ-ketoaldehyde (γKA) induce endoplasmic reticulum stress and endothelial activation. | Guo L, Chen Z, Cox BE, Amarnath V, Epand RF, Epand RM, Davies SS | The Journal of biological chemistry | 21454544 | J Biol Chem | 2011 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/21454544 |
Regulation of ubiquitin chain initiation to control the timing of substrate degradation. | Williamson A, Banerjee S, Zhu X, Philipp I, Iavarone AT, Rape M | Molecular cell | 21700221 | Mol Cell | 2011 Jun 24 | https://www.ncbi.nlm.nih.gov/pubmed/21700221 |
The multiple layers of ubiquitin-dependent cell cycle control. | Wickliffe K, Williamson A, Jin L, Rape M | Chemical reviews | 19146381 | Chem Rev | 2009 Apr | https://www.ncbi.nlm.nih.gov/pubmed/19146381 |
Reverse the curse--the role of deubiquitination in cell cycle control. | Song L, Rape M | Current opinion in cell biology | 18346885 | Curr Opin Cell Biol | 2008 Apr | https://www.ncbi.nlm.nih.gov/pubmed/18346885 |
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. | Jin L, Williamson A, Banerjee S, Philipp I, Rape M | Cell | 18485873 | Cell | 2008 May 16 | https://www.ncbi.nlm.nih.gov/pubmed/18485873 |
Processive ubiquitin chain formation by the anaphase-promoting complex. | Meyer HJ, Rape M | Seminars in cell & developmental biology | 21477659 | Semin Cell Dev Biol | 2011 Aug | https://www.ncbi.nlm.nih.gov/pubmed/21477659 |
The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2. | Wickliffe KE, Lorenz S, Wemmer DE, Kuriyan J, Rape M | Cell | 21376237 | Cell | 2011 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/21376237 |
Ubiquitin-dependent regulation of COPII coat size and function. | Jin L, Pahuja KB, Wickliffe KE, Gorur A, Baumgärtel C, Schekman R, Rape M | Nature | 22358839 | Nature | 2012 Feb 22 | https://www.ncbi.nlm.nih.gov/pubmed/22358839 |
K11-linked ubiquitin chains as novel regulators of cell division. | Wickliffe KE, Williamson A, Meyer HJ, Kelly A, Rape M | Trends in cell biology | 21978762 | Trends Cell Biol | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21978762 |
Regulated degradation of spindle assembly factors by the anaphase-promoting complex. | Song L, Rape M | Molecular cell | 20471943 | Mol Cell | 2010 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/20471943 |
Do Dog Behavioral Characteristics Predict the Quality of the Relationship between Dogs and Their Owners? | Hoffman CL, Chen P, Serpell JA, Jacobson KC | Human-animal interaction bulletin | 25685855 | Hum Anim Interact Bull | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/25685855 |
Community Violence Exposure and Adolescent Delinquency: Examining a Spectrum of Promotive Factors. | Chen P, Voisin DR, Jacobson KC | Youth & society | 33364640 | Youth Soc | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33364640 |
Moderating effects of childhood maltreatment on associations between social information processing and adult aggression. | Chen P, Coccaro EF, Lee R, Jacobson KC | Psychological medicine | 22008562 | Psychol Med | 2012 Jun | https://www.ncbi.nlm.nih.gov/pubmed/22008562 |
Developmental trajectories of substance use from early adolescence to young adulthood: gender and racial/ethnic differences. | Chen P, Jacobson KC | The Journal of adolescent health : official publication of the Society for Adolescent Medicine | 22265111 | J Adolesc Health | 2012 Feb | https://www.ncbi.nlm.nih.gov/pubmed/22265111 |
Longitudinal relationships between college education and patterns of heavy drinking: a comparison between Caucasians and African-Americans. | Chen P, Jacobson KC | The Journal of adolescent health : official publication of the Society for Adolescent Medicine | 23707401 | J Adolesc Health | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23707401 |
Hostile attributional bias, negative emotional responding, and aggression in adults: moderating effects of gender and impulsivity. | Chen P, Coccaro EF, Jacobson KC | Aggressive behavior | 24833604 | Aggress Behav | 2012 Jan-Feb | https://www.ncbi.nlm.nih.gov/pubmed/24833604 |
Community Violence Exposure and Sexual Behaviors in a Nationally Representative Sample of Young Adults: The Effects of Race/Ethnicity and Gender. | Voisin DR, Chen P, Fullilove R, Jacobson KC | Journal of social service research | 34321702 | J Soc Serv Res | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/34321702 |
The Differential Impact of Parenting on Adolescent Externalizing Behaviors in the Context of Maternal Stress. | Miller KN, Jacobson KC | Journal of youth and adolescence | 36807232 | J Youth Adolesc | 2023 Jul | https://www.ncbi.nlm.nih.gov/pubmed/36807232 |
Impulsivity moderates promotive environmental influences on adolescent delinquency: a comparison across family, school, and neighborhood contexts. | Chen P, Jacobson KC | Journal of abnormal child psychology | 23673971 | J Abnorm Child Psychol | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23673971 |
Associations Between Pet Ownership and Attitudes Toward Pets With Youth Socioemotional Outcomes. | Jacobson KC, Chang L | Frontiers in psychology | 30534102 | Front Psychol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30534102 |
Racial and ethnic comparison of ecological risk factors and youth outcomes: A test of the desensitization hypothesis. | Chen P, Voisin DR, Marotta PL, Jacobson KC | Journal of child and family studies | 33814876 | J Child Fam Stud | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33814876 |
Child psychopathic traits moderate relationships between parental affect and child aggression. | Yeh MT, Chen P, Raine A, Baker LA, Jacobson KC | Journal of the American Academy of Child and Adolescent Psychiatry | 21961779 | J Am Acad Child Adolesc Psychiatry | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21961779 |
Introduction to the special issue, pathways between genes, brain, and behavior. | Kremen WS, Jacobson KC | Behavior genetics | 20155393 | Behav Genet | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20155393 |
Microfluidic immobilization of physiologically active Caenorhabditis elegans. | Gilleland CL, Rohde CB, Zeng F, Yanik MF | Nature protocols | 21127483 | Nat Protoc | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21127483 |
Microfluidic in vivo screen identifies compounds enhancing neuronal regeneration. | Rohde CB, Gilleland C, Samara C, Norton S, Haggarty S, Yanik MF | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19965065 | Annu Int Conf IEEE Eng Med Biol Soc | 2009 | https://www.ncbi.nlm.nih.gov/pubmed/19965065 |
High-throughput in vivo vertebrate screening. | Pardo-Martin C, Chang TY, Koo BK, Gilleland CL, Wasserman SC, Yanik MF | Nature methods | 20639868 | Nat Methods | 2010 Aug | https://www.ncbi.nlm.nih.gov/pubmed/20639868 |
High-throughput in vivo genetic and drug screening using femtosecond laser nano-surgery, and microfluidics. | Rohde C, Gilleland C, Samara C, Zeng F, Yanik MF | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 19163246 | Annu Int Conf IEEE Eng Med Biol Soc | 2008 | https://www.ncbi.nlm.nih.gov/pubmed/19163246 |
Computer-Assisted Transgenesis of Caenorhabditis elegans for Deep Phenotyping. | Gilleland CL, Falls AT, Noraky J, Heiman MG, Yanik MF | Genetics | 26163188 | Genetics | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26163188 |
High-throughput hyperdimensional vertebrate phenotyping. | Pardo-Martin C, Allalou A, Medina J, Eimon PM, Wählby C, Fatih Yanik M | Nature communications | 23403568 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23403568 |
Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration. | Samara C, Rohde CB, Gilleland CL, Norton S, Haggarty SJ, Yanik MF | Proceedings of the National Academy of Sciences of the United States of America | 20937901 | Proc Natl Acad Sci U S A | 2010 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/20937901 |
Organ-targeted high-throughput in vivo biologics screen identifies materials for RNA delivery. | Chang TY, Shi P, Steinmeyer JD, Chatnuntawech I, Tillberg P, Love KT, Eimon PM, Anderson DG, Yanik MF | Integrative biology : quantitative biosciences from nano to macro | 25184623 | Integr Biol (Camb) | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25184623 |
Sub-cellular precision on-chip small-animal immobilization, multi-photon imaging and femtosecond-laser manipulation. | Zeng F, Rohde CB, Yanik MF | Lab on a chip | 18432331 | Lab Chip | 2008 May | https://www.ncbi.nlm.nih.gov/pubmed/18432331 |
Fully automated cellular-resolution vertebrate screening platform with parallel animal processing. | Chang TY, Pardo-Martin C, Allalou A, Wählby C, Yanik MF | Lab on a chip | 22159032 | Lab Chip | 2012 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/22159032 |
Large-scale analysis of neurite growth dynamics on micropatterned substrates. | Wissner-Gross ZD, Scott MA, Ku D, Ramaswamy P, Fatih Yanik M | Integrative biology : quantitative biosciences from nano to macro | 20976322 | Integr Biol (Camb) | 2011 Jan | https://www.ncbi.nlm.nih.gov/pubmed/20976322 |
Subcellular in vivo time-lapse imaging and optical manipulation of Caenorhabditis elegans in standard multiwell plates. | Rohde CB, Yanik MF | Nature communications | 21468023 | Nat Commun | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/21468023 |
Construction of a femtosecond laser microsurgery system. | Steinmeyer JD, Gilleland CL, Pardo-Martin C, Angel M, Rohde CB, Scott MA, Yanik MF | Nature protocols | 20203659 | Nat Protoc | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20203659 |
Dual-mode of insulin action controls GLUT4 vesicle exocytosis. | Xu Y, Rubin BR, Orme CM, Karpikov A, Yu C, Bogan JS, Toomre DK | The Journal of cell biology | 21555461 | J Cell Biol | 2011 May 16 | https://www.ncbi.nlm.nih.gov/pubmed/21555461 |
3-D reconstruction of microtubules from multi-angle total internal reflection fluorescence microscopy using Bayesian framework. | Yang Q, Karpikov A, Toomre D, Duncan JS | IEEE transactions on image processing : a publication of the IEEE Signal Processing Society | 21324778 | IEEE Trans Image Process | 2011 Aug | https://www.ncbi.nlm.nih.gov/pubmed/21324778 |
Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis. | Xu Y, Toomre DK, Bogan JS, Hao M | Journal of cellular and molecular medicine | 28544529 | J Cell Mol Med | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28544529 |
The Legionella pneumophila effector DrrA is sufficient to stimulate SNARE-dependent membrane fusion. | Arasaki K, Toomre DK, Roy CR | Cell host & microbe | 22264512 | Cell Host Microbe | 2012 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/22264512 |
Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells. | Tkachenko E, Tse D, Sideleva O, Deharvengt SJ, Luciano MR, Xu Y, McGarry CL, Chidlow J, Pilch PF, Sessa WC, Toomre DK, Stan RV | PloS one | 22403691 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22403691 |
Using light to see and control membrane traffic. | Xu Y, Melia TJ, Toomre DK | Current opinion in chemical biology | 22079055 | Curr Opin Chem Biol | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22079055 |
A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. | Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P | Cell | 19303853 | Cell | 2009 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/19303853 |
Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis. | Goss JW, Toomre DK | The Journal of cell biology | 18573914 | J Cell Biol | 2008 Jun 30 | https://www.ncbi.nlm.nih.gov/pubmed/18573914 |
The IN/OUT assay: a new tool to study ciliogenesis. | Kukic I, Rivera-Molina F, Toomre D | Cilia | 27493724 | Cilia | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27493724 |
Live-cell imaging of exocyst links its spatiotemporal dynamics to various stages of vesicle fusion. | Rivera-Molina F, Toomre D | The Journal of cell biology | 23690179 | J Cell Biol | 2013 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/23690179 |
Deciphering subcellular processes in live imaging datasets via dynamic probabilistic networks. | Letinic K, Sebastian R, Barthel A, Toomre D | Bioinformatics (Oxford, England) | 20581401 | Bioinformatics | 2010 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/20581401 |
A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils. | Zhang Y, Tang W, Zhang H, Niu X, Xu Y, Zhang J, Gao K, Pan W, Boggon TJ, Toomre D, Min W, Wu D | Developmental cell | 24176643 | Dev Cell | 2013 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/24176643 |
An expectation maximization based method for subcellular particle tracking using multi-angle TIRF microscopy. | Liang L, Shen H, De Camilli P, Toomre DK, Duncan JS | Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention | 22003671 | Med Image Comput Comput Assist Interv | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22003671 |
Super-resolution imaging of the Golgi in live cells with a bioorthogonal ceramide probe. | Erdmann RS, Takakura H, Thompson AD, Rivera-Molina F, Allgeyer ES, Bewersdorf J, Toomre D, Schepartz A | Angewandte Chemie (International ed. in English) | 25081303 | Angew Chem Int Ed Engl | 2014 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/25081303 |
A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules. | Nelson JW, Chamessian AG, McEnaney PJ, Murelli RP, Kazmierczak BI, Spiegel DA | ACS chemical biology | 20923200 | ACS Chem Biol | 2010 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/20923200 |
Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators. | Jakobsche CE, Parker CG, Tao RN, Kolesnikova MD, Douglass EF Jr, Spiegel DA | ACS chemical biology | 24053626 | ACS Chem Biol | 2013 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/24053626 |
Exploring post-translational arginine modification using chemically synthesized methylglyoxal hydroimidazolones. | Wang T, Kartika R, Spiegel DA | Journal of the American Chemical Society | 22591136 | J Am Chem Soc | 2012 May 30 | https://www.ncbi.nlm.nih.gov/pubmed/22591136 |
Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus. | Gautam S, Kim T, Lester E, Deep D, Spiegel DA | ACS chemical biology | 26502318 | ACS Chem Biol | 2016 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/26502318 |
An antibody-recruiting small molecule that targets HIV gp120. | Parker CG, Domaoal RA, Anderson KS, Spiegel DA | Journal of the American Chemical Society | 19839582 | J Am Chem Soc | 2009 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/19839582 |
Chemical probes reveal an extraseptal mode of cross-linking in Staphylococcus aureus. | Gautam S, Kim T, Spiegel DA | Journal of the American Chemical Society | 26035224 | J Am Chem Soc | 2015 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/26035224 |
A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules. | Zhang AX, Murelli RP, Barinka C, Michel J, Cocleaza A, Jorgensen WL, Lubkowski J, Spiegel DA | Journal of the American Chemical Society | 20726553 | J Am Chem Soc | 2010 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/20726553 |
Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease. | McEnaney PJ, Parker CG, Zhang AX, Spiegel DA | ACS chemical biology | 22758917 | ACS Chem Biol | 2012 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/22758917 |
Exterior design: strategies for redecorating the bacterial surface with small molecules. | Gautam S, Gniadek TJ, Kim T, Spiegel DA | Trends in biotechnology | 23490213 | Trends Biotechnol | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23490213 |
A comprehensive mathematical model for three-body binding equilibria. | Douglass EF Jr, Miller CJ, Sparer G, Shapiro H, Spiegel DA | Journal of the American Chemical Society | 23544844 | J Am Chem Soc | 2013 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/23544844 |
Spatiotemporal control over molecular delivery and cellular encapsulation from electropolymerized micro- and nanopatterned surfaces. | Stern E, Jay SM, Demento SL, Murelli RP, Reed MA, Malinski T, Spiegel DA, Mooney DJ, Fahmy TM | Advanced functional materials | 20445826 | Adv Funct Mater | 2009 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/20445826 |
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Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules. | Parker CG, Dahlgren MK, Tao RN, Li DT, Douglass EF Jr, Shoda T, Jawanda N, Spasov KA, Lee S, Zhou N, Domaoal RA, Sutton RE, Anderson KS, Jorgensen WL, Krystal M, Spiegel DA | Chemical science | 25379167 | Chem Sci | 2014 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/25379167 |
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Functional analysis of protein targets by metabolomic approaches. | Kim YG, Saghatelian A | Topics in current chemistry | 22083210 | Top Curr Chem | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22083210 |
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Peptidomics approach to elucidate the proteolytic regulation of bioactive peptides. | Kim YG, Lone AM, Nolte WM, Saghatelian A | Proceedings of the National Academy of Sciences of the United States of America | 22586115 | Proc Natl Acad Sci U S A | 2012 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/22586115 |
Proteolysis controls endogenous substance P levels. | Mitchell AJ, Lone AM, Tinoco AD, Saghatelian A | PloS one | 23894327 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23894327 |
Peptidomics methods for the identification of peptidase-substrate interactions. | Lone AM, Kim YG, Saghatelian A | Current opinion in chemical biology | 23332665 | Curr Opin Chem Biol | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23332665 |
Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. | Maianti JP, McFedries A, Foda ZH, Kleiner RE, Du XQ, Leissring MA, Tang WJ, Charron MJ, Seeliger MA, Saghatelian A, Liu DR | Nature | 24847884 | Nature | 2014 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/24847884 |
Discovery of a protein-metabolite interaction between unsaturated fatty acids and the nuclear receptor Nur77 using a metabolomics approach. | Vinayavekhin N, Saghatelian A | Journal of the American Chemical Society | 21973308 | J Am Chem Soc | 2011 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/21973308 |
Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling. | Rodgers MA, Saghatelian A, Yang PL | Journal of the American Chemical Society | 19301856 | J Am Chem Soc | 2009 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/19301856 |
Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform. | Tinoco AD, Tagore DM, Saghatelian A | Journal of the American Chemical Society | 20178363 | J Am Chem Soc | 2010 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/20178363 |
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Analysis of the proteolysis of bioactive peptides using a peptidomics approach. | Kim YG, Lone AM, Saghatelian A | Nature protocols | 23949379 | Nat Protoc | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23949379 |
Peptidase substrates via global peptide profiling. | Tagore DM, Nolte WM, Neveu JM, Rangel R, Guzman-Rojas L, Pasqualini R, Arap W, Lane WS, Saghatelian A | Nature chemical biology | 19011639 | Nat Chem Biol | 2009 Jan | https://www.ncbi.nlm.nih.gov/pubmed/19011639 |
Peptidomics of prolyl endopeptidase in the central nervous system. | Nolte WM, Tagore DM, Lane WS, Saghatelian A | Biochemistry | 19911840 | Biochemistry | 2009 Dec 22 | https://www.ncbi.nlm.nih.gov/pubmed/19911840 |
A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones. | Tinoco AD, Kim YG, Tagore DM, Wiwczar J, Lane WS, Danial NN, Saghatelian A | Biochemistry | 21299233 | Biochemistry | 2011 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/21299233 |
A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors. | Lone AM, Bachovchin DA, Westwood DB, Speers AE, Spicer TP, Fernandez-Vega V, Chase P, Hodder PS, Rosen H, Cravatt BF, Saghatelian A | Journal of the American Chemical Society | 21692504 | J Am Chem Soc | 2011 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/21692504 |
Alternative splicing of CHEK2 and codeletion with NF2 promote chromosomal instability in meningioma. | Yang HW, Kim TM, Song SS, Shrinath N, Park R, Kalamarides M, Park PJ, Black PM, Carroll RS, Johnson MD | Neoplasia (New York, N.Y.) | 22355270 | Neoplasia | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22355270 |
MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma. | Zhao Y, Huang W, Kim TM, Jung Y, Menon LG, Xing H, Li H, Carroll RS, Park PJ, Yang HW, Johnson MD | Journal of experimental & clinical cancer research : CR | 30683134 | J Exp Clin Cancer Res | 2019 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/30683134 |
Functional genomic analysis of chromosomal aberrations in a compendium of 8000 cancer genomes. | Kim TM, Xi R, Luquette LJ, Park RW, Johnson MD, Park PJ | Genome research | 23132910 | Genome Res | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23132910 |
The imprinted gene PEG3 inhibits Wnt signaling and regulates glioma growth. | Jiang X, Yu Y, Yang HW, Agar NY, Frado L, Johnson MD | The Journal of biological chemistry | 20064927 | J Biol Chem | 2010 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/20064927 |
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Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers. | Dreyfuss JM, Johnson MD, Park PJ | Molecular cancer | 19732454 | Mol Cancer | 2009 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/19732454 |
Numb regulates glioma stem cell fate and growth by altering epidermal growth factor receptor and Skp1-Cullin-F-box ubiquitin ligase activity. | Jiang X, Xing H, Kim TM, Jung Y, Huang W, Yang HW, Song S, Park PJ, Carroll RS, Johnson MD | Stem cells (Dayton, Ohio) | 22553175 | Stem Cells | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22553175 |
KAP regulates ROCK2 and Cdk2 in an RNA-activated glioblastoma invasion pathway. | Li H, Jiang X, Yu Y, Huang W, Xing H, Agar NY, Yang HW, Yang B, Carroll RS, Johnson MD | Oncogene | 24704824 | Oncogene | 2015 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/24704824 |
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Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli. | Gat-Viks I, Chevrier N, Wilentzik R, Eisenhaure T, Raychowdhury R, Steuerman Y, Shalek AK, Hacohen N, Amit I, Regev A | Nature biotechnology | 23503680 | Nat Biotechnol | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23503680 |
RNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels. | Astier AL, Beriou G, Eisenhaure TM, Anderton SM, Hafler DA, Hacohen N | Journal of immunology (Baltimore, Md. : 1950) | 20018615 | J Immunol | 2010 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/20018615 |
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Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia. | Shalek AK, Gaublomme JT, Wang L, Yosef N, Chevrier N, Andersen MS, Robinson JT, Pochet N, Neuberg D, Gertner RS, Amit I, Brown JR, Hacohen N, Regev A, Wu CJ, Park H | Nano letters | 23190424 | Nano Lett | 2012 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/23190424 |
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Systematic discovery of TLR signaling components delineates viral-sensing circuits. | Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF, Gat-Viks I, Tonti E, DeGrace MM, Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, Andersen MS, Root DE, von Andrian U, Jones RB, Park H, Carr SA, Regev A, Amit I, Hacohen N | Cell | 22078882 | Cell | 2011 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/22078882 |
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CD209a expression on dendritic cells is critical for the development of pathogenic Th17 cell responses in murine schistosomiasis. | Ponichtera HE, Shainheit MG, Liu BC, Raychowdhury R, Larkin BM, Russo JM, Salantes DB, Lai CQ, Parnell LD, Yun TJ, Cheong C, Bunnell SC, Hacohen N, Stadecker MJ | Journal of immunology (Baltimore, Md. : 1950) | 24729611 | J Immunol | 2014 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/24729611 |
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IRF3 inhibits IFN-γ-mediated restriction of intracellular pathogens in macrophages independently of IFNAR. | Maciag K, Raychowdhury R, Smith K, Schneider AM, Coers J, Mumbach MR, Schwartz S, Hacohen N | Journal of leukocyte biology | 34826345 | J Leukoc Biol | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34826345 |
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A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. | Garber M, Yosef N, Goren A, Raychowdhury R, Thielke A, Guttman M, Robinson J, Minie B, Chevrier N, Itzhaki Z, Blecher-Gonen R, Bornstein C, Amann-Zalcenstein D, Weiner A, Friedrich D, Meldrim J, Ram O, Cheng C, Gnirke A, Fisher S, Friedman N, Wong B, Bernstein BE, Nusbaum C, Hacohen N, Regev A, Amit I | Molecular cell | 22940246 | Mol Cell | 2012 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/22940246 |
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A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection. | Shapira SD, Gat-Viks I, Shum BO, Dricot A, de Grace MM, Wu L, Gupta PB, Hao T, Silver SJ, Root DE, Hill DE, Regev A, Hacohen N | Cell | 20064372 | Cell | 2009 Dec 24 | https://www.ncbi.nlm.nih.gov/pubmed/20064372 |
High-Q optical sensors for chemical and biological analysis. | Luchansky MS, Bailey RC | Analytical chemistry | 22111937 | Anal Chem | 2012 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/22111937 |
Label-free virus detection using silicon photonic microring resonators. | McClellan MS, Domier LL, Bailey RC | Biosensors & bioelectronics | 22138465 | Biosens Bioelectron | 2012 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/22138465 |
Real-time monitoring of surface-initiated atom transfer radical polymerization using silicon photonic microring resonators: implications for combinatorial screening of polymer brush growth conditions. | Limpoco FT, Bailey RC | Journal of the American Chemical Society | 21899288 | J Am Chem Soc | 2011 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/21899288 |
Biomolecular analysis with microring resonators: applications in multiplexed diagnostics and interaction screening. | Kindt JT, Bailey RC | Current opinion in chemical biology | 23871688 | Curr Opin Chem Biol | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23871688 |
Interfacing lipid bilayer nanodiscs and silicon photonic sensor arrays for multiplexed protein-lipid and protein-membrane protein interaction screening. | Sloan CD, Marty MT, Sligar SG, Bailey RC | Analytical chemistry | 23425255 | Anal Chem | 2013 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/23425255 |
Label-free quantitation of a cancer biomarker in complex media using silicon photonic microring resonators. | Washburn AL, Gunn LC, Bailey RC | Analytical chemistry | 19848413 | Anal Chem | 2009 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/19848413 |
Nonlinear analyte concentration gradients for one-step kinetic analysis employing optical microring resonators. | Marty MT, Sloan CD, Bailey RC, Sligar SG | Analytical chemistry | 22686186 | Anal Chem | 2012 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/22686186 |
Isothermal discrimination of single-nucleotide polymorphisms via real-time kinetic desorption and label-free detection of DNA using silicon photonic microring resonator arrays. | Qavi AJ, Mysz TM, Bailey RC | Analytical chemistry | 21834517 | Anal Chem | 2011 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/21834517 |
Rapid, multiparameter profiling of cellular secretion using silicon photonic microring resonator arrays. | Luchansky MS, Bailey RC | Journal of the American Chemical Society | 22040005 | J Am Chem Soc | 2011 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/22040005 |
Multiplexed cancer biomarker detection using chip-integrated silicon photonic sensor arrays. | Washburn AL, Shia WW, Lenkeit KA, Lee SH, Bailey RC | The Analyst | 27400767 | Analyst | 2016 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/27400767 |
Silicon photonic microring resonators for quantitative cytokine detection and T-cell secretion analysis. | Luchansky MS, Bailey RC | Analytical chemistry | 20143780 | Anal Chem | 2010 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/20143780 |
Anti-DNA:RNA antibodies and silicon photonic microring resonators: increased sensitivity for multiplexed microRNA detection. | Qavi AJ, Kindt JT, Gleeson MA, Bailey RC | Analytical chemistry | 21711056 | Anal Chem | 2011 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/21711056 |
DNA-encoding to improve performance and allow parallel evaluation of the binding characteristics of multiple antibodies in a surface-bound immunoassay format. | Washburn AL, Gomez J, Bailey RC | Analytical chemistry | 21438633 | Anal Chem | 2011 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/21438633 |
Quantitative, label-free detection of five protein biomarkers using multiplexed arrays of silicon photonic microring resonators. | Washburn AL, Luchansky MS, Bowman AL, Bailey RC | Analytical chemistry | 20000326 | Anal Chem | 2010 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/20000326 |
Nanostructured Substrates for Optical Sensing. | Kemling JW, Qavi AJ, Bailey RC, Suslick KS | The journal of physical chemistry letters | 22174955 | J Phys Chem Lett | 2011 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/22174955 |
Efficient bioconjugation of protein capture agents to biosensor surfaces using aniline-catalyzed hydrazone ligation. | Byeon JY, Limpoco FT, Bailey RC | Langmuir : the ACS journal of surfaces and colloids | 20809595 | Langmuir | 2010 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/20809595 |
Sensitive on-chip detection of a protein biomarker in human serum and plasma over an extended dynamic range using silicon photonic microring resonators and sub-micron beads. | Luchansky MS, Washburn AL, McClellan MS, Bailey RC | Lab on a chip | 21541438 | Lab Chip | 2011 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/21541438 |
Grand challenge commentary: Informative diagnostics for personalized medicine. | Bailey RC | Nature chemical biology | 21079587 | Nat Chem Biol | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21079587 |
Photonics-on-a-chip: recent advances in integrated waveguides as enabling detection elements for real-world, lab-on-a-chip biosensing applications. | Washburn AL, Bailey RC | The Analyst | 20957245 | Analyst | 2011 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/20957245 |
Chaperone probes and bead-based enhancement to improve the direct detection of mRNA using silicon photonic sensor arrays. | Kindt JT, Bailey RC | Analytical chemistry | 22913333 | Anal Chem | 2012 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/22913333 |
Single domain antibodies for the detection of ricin using silicon photonic microring resonator arrays. | Shia WW, Bailey RC | Analytical chemistry | 23268548 | Anal Chem | 2013 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/23268548 |
Subpicogram per milliliter detection of interleukins using silicon photonic microring resonators and an enzymatic signal enhancement strategy. | Kindt JT, Luchansky MS, Qavi AJ, Lee SH, Bailey RC | Analytical chemistry | 24171505 | Anal Chem | 2013 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/24171505 |
Sizing up the future of microRNA analysis. | Qavi AJ, Kindt JT, Bailey RC | Analytical and bioanalytical chemistry | 20680616 | Anal Bioanal Chem | 2010 Nov | https://www.ncbi.nlm.nih.gov/pubmed/20680616 |
Multiplexed evaluation of capture agent binding kinetics using arrays of silicon photonic microring resonators. | Byeon JY, Bailey RC | The Analyst | 21085731 | Analyst | 2011 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/21085731 |
Label-free technologies for quantitative multiparameter biological analysis. | Qavi AJ, Washburn AL, Byeon JY, Bailey RC | Analytical and bioanalytical chemistry | 19221722 | Anal Bioanal Chem | 2009 May | https://www.ncbi.nlm.nih.gov/pubmed/19221722 |
Label-free, multiplexed detection of bacterial tmRNA using silicon photonic microring resonators. | Scheler O, Kindt JT, Qavi AJ, Kaplinski L, Glynn B, Barry T, Kurg A, Bailey RC | Biosensors & bioelectronics | 22541813 | Biosens Bioelectron | 2012 Jun-Jul | https://www.ncbi.nlm.nih.gov/pubmed/22541813 |
Research Spotlight: New multiparameter bioanalytical technologies for applications in personalized medicine, drug discovery and fundamental biology. | Bailey RC | Bioanalysis | 21083072 | Bioanalysis | 2009 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21083072 |
Characterization of the evanescent field profile and bound mass sensitivity of a label-free silicon photonic microring resonator biosensing platform. | Luchansky MS, Washburn AL, Martin TA, Iqbal M, Gunn LC, Bailey RC | Biosensors & bioelectronics | 20708399 | Biosens Bioelectron | 2010 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/20708399 |
Magnetically-actuated, bead-enhanced silicon photonic immunosensor. | Valera E, McClellan MS, Bailey RC | Analytical methods : advancing methods and applications | 26528374 | Anal Methods | 2015 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/26528374 |
Multiplexed detection and label-free quantitation of microRNAs using arrays of silicon photonic microring resonators. | Qavi AJ, Bailey RC | Angewandte Chemie (International ed. in English) | 20491114 | Angew Chem Int Ed Engl | 2010 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/20491114 |
Countering amyloid polymorphism and drug resistance with minimal drug cocktails. | Duennwald ML, Shorter J | Prion | 20935457 | Prion | 2010 Oct-Dec | https://www.ncbi.nlm.nih.gov/pubmed/20935457 |
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. | Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, MacLea KS, Freibaum B, Li S, Molliex A, Kanagaraj AP, Carter R, Boylan KB, Wojtas AM, Rademakers R, Pinkus JL, Greenberg SA, Trojanowski JQ, Traynor BJ, Smith BN, Topp S, Gkazi AS, Miller J, Shaw CE, Kottlors M, Kirschner J, Pestronk A, Li YR, Ford AF, Gitler AD, Benatar M, King OD, Kimonis VE, Ross ED, Weihl CC, Shorter J, Taylor JP | Nature | 23455423 | Nature | 2013 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/23455423 |
Applying Hsp104 to protein-misfolding disorders. | Vashist S, Cushman M, Shorter J | Biochemistry and cell biology = Biochimie et biologie cellulaire | 20130674 | Biochem Cell Biol | 2010 Feb | https://www.ncbi.nlm.nih.gov/pubmed/20130674 |
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Multiwaveguide implantable probe for light delivery to sets of distributed brain targets. | Zorzos AN, Boyden ES, Fonstad CG | Optics letters | 21165114 | Opt Lett | 2010 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/21165114 |
Striatal origin of the pathologic beta oscillations in Parkinson's disease. | McCarthy MM, Moore-Kochlacs C, Gu X, Boyden ES, Han X, Kopell N | Proceedings of the National Academy of Sciences of the United States of America | 21697509 | Proc Natl Acad Sci U S A | 2011 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/21697509 |
Face-selective electrostatic control of hydrothermal zinc oxide nanowire synthesis. | Joo J, Chow BY, Prakash M, Boyden ES, Jacobson JM | Nature materials | 21743451 | Nat Mater | 2011 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/21743451 |
Mechanistic insights into radical formation and functionalization in copper/N-fluorobenzenesulfonimide radical-relay reactions. | Mandal M, Buss JA, Chen SJ, Cramer CJ, Stahl SS | Chemical science | 38274066 | Chem Sci | 2024 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/38274066 |
Capturing the herpes simplex virus core fusion complex (gB-gH/gL) in an acidic environment. | Cairns TM, Whitbeck JC, Lou H, Heldwein EE, Chowdary TK, Eisenberg RJ, Cohen GH | Journal of virology | 21507973 | J Virol | 2011 Jul | https://www.ncbi.nlm.nih.gov/pubmed/21507973 |
Entry of herpesviruses into cells: more than one way to pull the trigger. | Heldwein EE | Structure (London, England : 1993) | 19217384 | Structure | 2009 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/19217384 |
Fusion-deficient insertion mutants of herpes simplex virus type 1 glycoprotein B adopt the trimeric postfusion conformation. | Silverman JL, Sharma S, Cairns TM, Heldwein EE | Journal of virology | 19939928 | J Virol | 2010 Feb | https://www.ncbi.nlm.nih.gov/pubmed/19939928 |
Characterization of Vesicular Stomatitis Virus Pseudotypes Bearing Essential Entry Glycoproteins gB, gD, gH, and gL of Herpes Simplex Virus 1. | Rogalin HB, Heldwein EE | Journal of virology | 27605677 | J Virol | 2016 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/27605677 |
HCMV gB shares structural and functional properties with gB proteins from other herpesviruses. | Sharma S, Wisner TW, Johnson DC, Heldwein EE | Virology | 23089254 | Virology | 2013 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/23089254 |
Syncytial phenotype of C-terminally truncated herpes simplex virus type 1 gB is associated with diminished membrane interactions. | Chowdary TK, Heldwein EE | Journal of virology | 20200237 | J Virol | 2010 May | https://www.ncbi.nlm.nih.gov/pubmed/20200237 |
Entry of herpesviruses into mammalian cells. | Heldwein EE, Krummenacher C | Cellular and molecular life sciences : CMLS | 18351291 | Cell Mol Life Sci | 2008 Jun | https://www.ncbi.nlm.nih.gov/pubmed/18351291 |
Mutations in the cytoplasmic tail of herpes simplex virus 1 gH reduce the fusogenicity of gB in transfected cells. | Silverman JL, Heldwein EE | Journal of virology | 23843635 | J Virol | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23843635 |
Expression, purification, and crystallization of HSV-1 glycoproteins for structure determination. | Stampfer SD, Heldwein EE | Methods in molecular biology (Clifton, N.J.) | 24671689 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24671689 |
Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. | Stampfer SD, Lou H, Cohen GH, Eisenberg RJ, Heldwein EE | Journal of virology | 20943984 | J Virol | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/20943984 |
Stuck in the middle: structural insights into the role of the gH/gL heterodimer in herpesvirus entry. | Stampfer SD, Heldwein EE | Current opinion in virology | 23107819 | Curr Opin Virol | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23107819 |
Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL. | Chowdary TK, Cairns TM, Atanasiu D, Cohen GH, Eisenberg RJ, Heldwein EE | Nature structural & molecular biology | 20601960 | Nat Struct Mol Biol | 2010 Jul | https://www.ncbi.nlm.nih.gov/pubmed/20601960 |
Crystal structure of the herpesvirus inner tegument protein UL37 supports its essential role in control of viral trafficking. | Pitts JD, Klabis J, Richards AL, Smith GA, Heldwein EE | Journal of virology | 24599989 | J Virol | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24599989 |
Expression, Purification, and Crystallization of HSV-1 Glycoproteins for Structure Determination. | White EM, Stampfer SD, Heldwein EE | Methods in molecular biology (Clifton, N.J.) | 31617192 | Methods Mol Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/31617192 |
Expression, Purification, and Crystallization of Full-Length HSV-1 gB for Structure Determination. | Cooper RS, Heldwein EE | Methods in molecular biology (Clifton, N.J.) | 31617193 | Methods Mol Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/31617193 |
A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer. | Sparano JA, Gray R, Oktay MH, Entenberg D, Rohan T, Xue X, Donovan M, Peterson M, Shuber A, Hamilton DA, D'Alfonso T, Goldstein LJ, Gertler F, Davidson NE, Condeelis J, Jones J | NPJ breast cancer | 29138761 | NPJ Breast Cancer | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29138761 |
Data publication with the structural biology data grid supports live analysis. | Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P | Nature communications | 26947396 | Nat Commun | 2016 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/26947396 |
Extensive mutagenesis of the HSV-1 gB ectodomain reveals remarkable stability of its postfusion form. | Vitu E, Sharma S, Stampfer SD, Heldwein EE | Journal of molecular biology | 23500487 | J Mol Biol | 2013 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/23500487 |
Membrane requirement for folding of the herpes simplex virus 1 gB cytodomain suggests a unique mechanism of fusion regulation. | Silverman JL, Greene NG, King DS, Heldwein EE | Journal of virology | 22623783 | J Virol | 2012 Aug | https://www.ncbi.nlm.nih.gov/pubmed/22623783 |
Signaling cell death from the endoplasmic reticulum stress response. | Shore GC, Papa FR, Oakes SA | Current opinion in cell biology | 21146390 | Curr Opin Cell Biol | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21146390 |
Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress. | Igbaria A, Merksamer PI, Trusina A, Tilahun F, Johnson JR, Brandman O, Krogan NJ, Weissman JS, Papa FR | Proceedings of the National Academy of Sciences of the United States of America | 31101715 | Proc Natl Acad Sci U S A | 2019 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/31101715 |
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. | Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, Oakes SA, Papa FR | Cell metabolism | 22883233 | Cell Metab | 2012 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/22883233 |
Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions. | Merksamer PI, Trusina A, Papa FR | Cell | 19026441 | Cell | 2008 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/19026441 |
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. | Ghosh R, Wang L, Wang ES, Perera BG, Igbaria A, Morita S, Prado K, Thamsen M, Caswell D, Macias H, Weiberth KF, Gliedt MJ, Alavi MV, Hari SB, Mitra AK, Bhhatarai B, Schürer SC, Snapp EL, Gould DB, German MS, Backes BJ, Maly DJ, Oakes SA, Papa FR | Cell | 25018104 | Cell | 2014 Jul 31 | https://www.ncbi.nlm.nih.gov/pubmed/25018104 |
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Han D, Lerner AG, Vande Walle L, Upton JP, Xu W, Hagen A, Backes BJ, Oakes SA, Papa FR | Cell | 19665977 | Cell | 2009 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/19665977 |
The UPR and cell fate at a glance. | Merksamer PI, Papa FR | Journal of cell science | 20332117 | J Cell Sci | 2010 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/20332117 |
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. | Upton JP, Wang L, Han D, Wang ES, Huskey NE, Lim L, Truitt M, McManus MT, Ruggero D, Goga A, Papa FR, Oakes SA | Science (New York, N.Y.) | 23042294 | Science | 2012 Nov 9 | https://www.ncbi.nlm.nih.gov/pubmed/23042294 |
Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors. | Wang L, Perera BG, Hari SB, Bhhatarai B, Backes BJ, Seeliger MA, Schürer SC, Oakes SA, Papa FR, Maly DJ | Nature chemical biology | 23086298 | Nat Chem Biol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23086298 |
Druggable sensors of the unfolded protein response. | Maly DJ, Papa FR | Nature chemical biology | 25325700 | Nat Chem Biol | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25325700 |
Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress. | Upton JP, Austgen K, Nishino M, Coakley KM, Hagen A, Han D, Papa FR, Oakes SA | Molecular and cellular biology | 18426910 | Mol Cell Biol | 2008 Jun | https://www.ncbi.nlm.nih.gov/pubmed/18426910 |
An oracle: antituberculosis pharmacokinetics-pharmacodynamics, clinical correlation, and clinical trial simulations to predict the future. | Pasipanodya J, Gumbo T | Antimicrobial agents and chemotherapy | 20937778 | Antimicrob Agents Chemother | 2011 Jan | https://www.ncbi.nlm.nih.gov/pubmed/20937778 |
A new evolutionary and pharmacokinetic-pharmacodynamic scenario for rapid emergence of resistance to single and multiple anti-tuberculosis drugs. | Pasipanodya JG, Gumbo T | Current opinion in pharmacology | 21807559 | Curr Opin Pharmacol | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21807559 |
Therapy duration and long-term outcomes in extra-pulmonary tuberculosis. | Pusch T, Pasipanodya JG, Hall RG 2nd, Gumbo T | BMC infectious diseases | 24580808 | BMC Infect Dis | 2014 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/24580808 |
Thioridazine pharmacokinetic-pharmacodynamic parameters "Wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congeners. | Musuka S, Srivastava S, Siyambalapitiyage Dona CW, Meek C, Leff R, Pasipanodya J, Gumbo T | Antimicrobial agents and chemotherapy | 24041886 | Antimicrob Agents Chemother | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24041886 |
New susceptibility breakpoints for first-line antituberculosis drugs based on antimicrobial pharmacokinetic/pharmacodynamic science and population pharmacokinetic variability. | Gumbo T | Antimicrobial agents and chemotherapy | 20086150 | Antimicrob Agents Chemother | 2010 Apr | https://www.ncbi.nlm.nih.gov/pubmed/20086150 |
Redefining multidrug-resistant tuberculosis based on clinical response to combination therapy. | Gumbo T, Pasipanodya JG, Wash P, Burger A, McIlleron H | Antimicrobial agents and chemotherapy | 25092691 | Antimicrob Agents Chemother | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25092691 |
Transformation Morphisms and Time-to-Extinction Analysis That Map Therapy Duration From Preclinical Models to Patients With Tuberculosis: Translating From Apples to Oranges. | Magombedze G, Pasipanodya JG, Srivastava S, Deshpande D, Visser ME, Chigutsa E, McIlleron H, Gumbo T | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 30496464 | Clin Infect Dis | 2018 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/30496464 |
A Long-term Co-perfused Disseminated Tuberculosis-3D Liver Hollow Fiber Model for Both Drug Efficacy and Hepatotoxicity in Babies. | Srivastava S, Pasipanodya JG, Ramachandran G, Deshpande D, Shuford S, Crosswell HE, Cirrincione KN, Sherman CM, Swaminathan S, Gumbo T | EBioMedicine | 27211555 | EBioMedicine | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/27211555 |
Susceptibility Testing of Antibiotics That Degrade Faster than the Doubling Time of Slow-Growing Mycobacteria: Ertapenem Sterilizing Effect versus Mycobacterium tuberculosis. | Srivastava S, van Rijn SP, Wessels AM, Alffenaar JW, Gumbo T | Antimicrobial agents and chemotherapy | 26926650 | Antimicrob Agents Chemother | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26926650 |
Pharmacokinetics-pharmacodynamics of pyrazinamide in a novel in vitro model of tuberculosis for sterilizing effect: a paradigm for faster assessment of new antituberculosis drugs. | Gumbo T, Dona CS, Meek C, Leff R | Antimicrobial agents and chemotherapy | 19451303 | Antimicrob Agents Chemother | 2009 Aug | https://www.ncbi.nlm.nih.gov/pubmed/19451303 |
Clinical and toxicodynamic evidence that high-dose pyrazinamide is not more hepatotoxic than the low doses currently used. | Pasipanodya JG, Gumbo T | Antimicrobial agents and chemotherapy | 20439617 | Antimicrob Agents Chemother | 2010 Jul | https://www.ncbi.nlm.nih.gov/pubmed/20439617 |
Pegylated interferon fractal pharmacokinetics: individualized dosing for hepatitis C virus infection. | Jain MK, Pasipanodya JG, Alder L, Lee WM, Gumbo T | Antimicrobial agents and chemotherapy | 23183434 | Antimicrob Agents Chemother | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23183434 |
Clofazimine for the Treatment of Mycobacterium kansasii. | Srivastava S, Gumbo T | Antimicrobial agents and chemotherapy | 29844047 | Antimicrob Agents Chemother | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29844047 |
The antibiotic resistance arrow of time: efflux pump induction is a general first step in the evolution of mycobacterial drug resistance. | Schmalstieg AM, Srivastava S, Belkaya S, Deshpande D, Meek C, Leff R, van Oers NS, Gumbo T | Antimicrobial agents and chemotherapy | 22751536 | Antimicrob Agents Chemother | 2012 Sep | https://www.ncbi.nlm.nih.gov/pubmed/22751536 |
Mycobacterial shuttle vectors designed for high-level protein expression in infected macrophages. | Eitson JL, Medeiros JJ, Hoover AR, Srivastava S, Roybal KT, Aínsa JA, Hansen EJ, Gumbo T, van Oers NS | Applied and environmental microbiology | 22820329 | Appl Environ Microbiol | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/22820329 |
Sterilizing Effect of Ertapenem-Clavulanate in a Hollow-Fiber Model of Tuberculosis and Implications on Clinical Dosing. | van Rijn SP, Srivastava S, Wessels MA, van Soolingen D, Alffenaar JC, Gumbo T | Antimicrobial agents and chemotherapy | 28696238 | Antimicrob Agents Chemother | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28696238 |
Serum drug concentrations predictive of pulmonary tuberculosis outcomes. | Pasipanodya JG, McIlleron H, Burger A, Wash PA, Smith P, Gumbo T | The Journal of infectious diseases | 23901086 | J Infect Dis | 2013 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/23901086 |
Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing. | Dheda K, Lenders L, Srivastava S, Magombedze G, Wainwright H, Raj P, Bush SJ, Pollara G, Steyn R, Davids M, Pooran A, Pennel T, Linegar A, McNerney R, Moodley L, Pasipanodya JG, Turner CT, Noursadeghi M, Warren RM, Wakeland E, Gumbo T | American journal of respiratory and critical care medicine | 30694692 | Am J Respir Crit Care Med | 2019 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/30694692 |
Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance. | Srivastava S, Deshpande D, Gumbo T | The Journal of antimicrobial chemotherapy | 28922805 | J Antimicrob Chemother | 2017 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/28922805 |
Efficacy Versus Hepatotoxicity of High-dose Rifampin, Pyrazinamide, and Moxifloxacin to Shorten Tuberculosis Therapy Duration: There Is Still Fight in the Old Warriors Yet! | Srivastava S, Deshpande D, Magombedze G, Gumbo T | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 30496465 | Clin Infect Dis | 2018 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/30496465 |
Rapid drug tolerance and dramatic sterilizing effect of moxifloxacin monotherapy in a novel hollow-fiber model of intracellular Mycobacterium kansasii disease. | Srivastava S, Pasipanodya J, Sherman CM, Meek C, Leff R, Gumbo T | Antimicrobial agents and chemotherapy | 25645830 | Antimicrob Agents Chemother | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25645830 |
In vitro activity of RX-P873 against Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. | Flamm RK, Rhomberg PR, Jones RN, Farrell DJ | Antimicrobial agents and chemotherapy | 25645834 | Antimicrob Agents Chemother | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25645834 |
Thioridazine as Chemotherapy for Mycobacterium avium Complex Diseases. | Deshpande D, Srivastava S, Musuka S, Gumbo T | Antimicrobial agents and chemotherapy | 27216055 | Antimicrob Agents Chemother | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27216055 |
Efflux-pump-derived multiple drug resistance to ethambutol monotherapy in Mycobacterium tuberculosis and the pharmacokinetics and pharmacodynamics of ethambutol. | Srivastava S, Musuka S, Sherman C, Meek C, Leff R, Gumbo T | The Journal of infectious diseases | 20210628 | J Infect Dis | 2010 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/20210628 |
Remote sites of structural atrophy predict later amyloid formation in a mouse model of Alzheimer's disease. | Badea A, Johnson GA, Jankowsky JL | NeuroImage | 20035883 | Neuroimage | 2010 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/20035883 |
Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. | Fowler SW, Chiang AC, Savjani RR, Larson ME, Sherman MA, Schuler DR, Cirrito JR, Lesné SE, Jankowsky JL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24899710 | J Neurosci | 2014 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/24899710 |
Intracerebroventricular viral injection of the neonatal mouse brain for persistent and widespread neuronal transduction. | Kim JY, Grunke SD, Levites Y, Golde TE, Jankowsky JL | Journal of visualized experiments : JoVE | 25286085 | J Vis Exp | 2014 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/25286085 |
Impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease. | Zhao R, Fowler SW, Chiang AC, Ji D, Jankowsky JL | Hippocampus | 24752989 | Hippocampus | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24752989 |
Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex. | Yetman MJ, Lillehaug S, Bjaalie JG, Leergaard TB, Jankowsky JL | Brain structure & function | 25869275 | Brain Struct Funct | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/25869275 |
Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability. | Zhao R, Grunke SD, Keralapurath MM, Yetman MJ, Lam A, Lee TC, Sousounis K, Jiang Y, Swing DA, Tessarollo L, Ji D, Jankowsky JL | Cell reports | 27373150 | Cell Rep | 2016 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/27373150 |
Wild-type neural progenitors divide and differentiate normally in an amyloid-rich environment. | Yetman MJ, Jankowsky JL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24174666 | J Neurosci | 2013 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/24174666 |
Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo. | Kim JY, Ash RT, Ceballos-Diaz C, Levites Y, Golde TE, Smirnakis SM, Jankowsky JL | The European journal of neuroscience | 23347239 | Eur J Neurosci | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/23347239 |
Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult. | Rodgers SP, Born HA, Das P, Jankowsky JL | Molecular neurodegeneration | 22709352 | Mol Neurodegener | 2012 Jun 18 | https://www.ncbi.nlm.nih.gov/pubmed/22709352 |
Strain background influences neurotoxicity and behavioral abnormalities in mice expressing the tetracycline transactivator. | Han HJ, Allen CC, Buchovecky CM, Yetman MJ, Born HA, Marin MA, Rodgers SP, Song BJ, Lu HC, Justice MJ, Probst FJ, Jankowsky JL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 22855807 | J Neurosci | 2012 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/22855807 |
Amyloid-β plaques disrupt axon initial segments. | Marin MA, Ziburkus J, Jankowsky J, Rasband MN | Experimental neurology | 27109181 | Exp Neurol | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27109181 |
Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis. | Chiang ACA, Fowler SW, Reddy R, Pletnikova O, Troncoso JC, Sherman MA, Lesne SE, Jankowsky JL | The American journal of pathology | 29248459 | Am J Pathol | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29248459 |
Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse. | Cowin RM, Roscic A, Bui N, Graham D, Paganetti P, Jankowsky JL, Weiss A, Paylor R | Behavioural brain research | 22306231 | Behav Brain Res | 2012 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/22306231 |
Brain-wide distribution of reporter expression in five transgenic tetracycline-transactivator mouse lines. | Lillehaug S, Yetman MJ, Puchades MA, Checinska MM, Kleven H, Jankowsky JL, Bjaalie JG, Leergaard TB | Scientific data | 30806643 | Sci Data | 2019 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/30806643 |
Robust amyloid clearance in a mouse model of Alzheimer's disease provides novel insights into the mechanism of amyloid-beta immunotherapy. | Wang A, Das P, Switzer RC 3rd, Golde TE, Jankowsky JL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 21411653 | J Neurosci | 2011 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/21411653 |
Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease. | Born HA, Kim JY, Savjani RR, Das P, Dabaghian YA, Guo Q, Yoo JW, Schuler DR, Cirrito JR, Zheng H, Golde TE, Noebels JL, Jankowsky JL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24623762 | J Neurosci | 2014 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/24623762 |
Specificity and efficiency of reporter expression in adult neural progenitors vary substantially among nestin-CreER(T2) lines. | Sun MY, Yetman MJ, Lee TC, Chen Y, Jankowsky JL | The Journal of comparative neurology | 24519019 | J Comp Neurol | 2014 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24519019 |
Progress in understanding reprogramming to the induced pluripotent state. | Plath K, Lowry WE | Nature reviews. Genetics | 21415849 | Nat Rev Genet | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21415849 |
Epigenetics of reprogramming to induced pluripotency. | Papp B, Plath K | Cell | 23498940 | Cell | 2013 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/23498940 |
The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo. | Minkovsky A, Barakat TS, Sellami N, Chin MH, Gunhanlar N, Gribnau J, Plath K | Cell reports | 23523354 | Cell Rep | 2013 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/23523354 |
Role of the murine reprogramming factors in the induction of pluripotency. | Sridharan R, Tchieu J, Mason MJ, Yachechko R, Kuoy E, Horvath S, Zhou Q, Plath K | Cell | 19167336 | Cell | 2009 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/19167336 |
Female human iPSCs retain an inactive X chromosome. | Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K | Cell stem cell | 20727844 | Cell Stem Cell | 2010 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/20727844 |
Pluripotency in 3D: genome organization in pluripotent cells. | Denholtz M, Plath K | Current opinion in cell biology | 23199754 | Curr Opin Cell Biol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23199754 |
X chromosome reactivation in reprogramming and in development. | Pasque V, Plath K | Current opinion in cell biology | 26540406 | Curr Opin Cell Biol | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26540406 |
Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. | Papp B, Plath K | Cell research | 21321600 | Cell Res | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21321600 |
X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. | Pasque V, Tchieu J, Karnik R, Uyeda M, Sadhu Dimashkie A, Case D, Papp B, Bonora G, Patel S, Ho R, Schmidt R, McKee R, Sado T, Tada T, Meissner A, Plath K | Cell | 25525883 | Cell | 2014 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/25525883 |
The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. | Minkovsky A, Sahakyan A, Rankin-Gee E, Bonora G, Patel S, Plath K | Epigenetics & chromatin | 25028596 | Epigenetics Chromatin | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25028596 |
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. | Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, Croce CM, Clark AT, Baxter T, Pyle AD, Teitell MA, Pelegrini M, Plath K, Lowry WE | Cell stem cell | 19570518 | Cell Stem Cell | 2009 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/19570518 |
Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. | Mason MJ, Fan G, Plath K, Zhou Q, Horvath S | BMC genomics | 19619308 | BMC Genomics | 2009 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/19619308 |
Concise review: Pluripotency and the transcriptional inactivation of the female Mammalian X chromosome. | Minkovsky A, Patel S, Plath K | Stem cells (Dayton, Ohio) | 21997775 | Stem Cells | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/21997775 |
Small RNAs loom large during reprogramming. | Sridharan R, Plath K | Cell stem cell | 21624799 | Cell Stem Cell | 2011 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/21624799 |
Mechanistic insights into reprogramming to induced pluripotency. | Ho R, Chronis C, Plath K | Journal of cellular physiology | 20945378 | J Cell Physiol | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/20945378 |
A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase. | Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K | Epigenetics & chromatin | 26468331 | Epigenetics Chromatin | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26468331 |
Stage-specific regulation of reprogramming to induced pluripotent stem cells by Wnt signaling and T cell factor proteins. | Ho R, Papp B, Hoffman JA, Merrill BJ, Plath K | Cell reports | 23791530 | Cell Rep | 2013 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/23791530 |
Identification of context-dependent motifs by contrasting ChIP binding data. | Mason MJ, Plath K, Zhou Q | Bioinformatics (Oxford, England) | 20870645 | Bioinformatics | 2010 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/20870645 |
Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. | Chin MH, Pellegrini M, Plath K, Lowry WE | Cell stem cell | 20682452 | Cell Stem Cell | 2010 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/20682452 |
Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. | Denholtz M, Bonora G, Chronis C, Splinter E, de Laat W, Ernst J, Pellegrini M, Plath K | Cell stem cell | 24035354 | Cell Stem Cell | 2013 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/24035354 |
High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome. | Keegan A, Plath K, Damoiseaux R | Methods in molecular biology (Clifton, N.J.) | 29671264 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29671264 |
Mediator coordinates PIC assembly with recruitment of CHD1. | Lin JJ, Lehmann LW, Bonora G, Sridharan R, Vashisht AA, Tran N, Plath K, Wohlschlegel JA, Carey M | Genes & development | 21979373 | Genes Dev | 2011 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/21979373 |
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. | McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M | Nature | 25915022 | Nature | 2015 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/25915022 |
Developmental shifts in the behavioral phenotypes of inbred mice: the role of postnatal and juvenile social experiences. | Curley JP, Rock V, Moynihan AM, Bateson P, Keverne EB, Champagne FA | Behavior genetics | 20130977 | Behav Genet | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20130977 |
Epigenetic influences on brain development and plasticity. | Fagiolini M, Jensen CL, Champagne FA | Current opinion in neurobiology | 19545993 | Curr Opin Neurobiol | 2009 Apr | https://www.ncbi.nlm.nih.gov/pubmed/19545993 |
The meaning of weaning: influence of the weaning period on behavioral development in mice. | Curley JP, Jordan ER, Swaney WT, Izraelit A, Kammel S, Champagne FA | Developmental neuroscience | 19546569 | Dev Neurosci | 2009 | https://www.ncbi.nlm.nih.gov/pubmed/19546569 |
Epigenetic influence of stress and the social environment. | Gudsnuk K, Champagne FA | ILAR journal | 23744967 | ILAR J | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23744967 |
Concordance in hippocampal and fecal Nr3c1 methylation is moderated by maternal behavior in the mouse. | Liberman SA, Mashoodh R, Thompson RC, Dolinoy DC, Champagne FA | Ecology and evolution | 23301177 | Ecol Evol | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23301177 |
Early interactions with mother and peers independently build adult social skills and shape BDNF and oxytocin receptor brain levels. | Branchi I, Curley JP, D'Andrea I, Cirulli F, Champagne FA, Alleva E | Psychoneuroendocrinology | 22910688 | Psychoneuroendocrinology | 2013 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22910688 |
How enrichment affects exploration trade-offs in rats: implications for welfare and well-being. | Franks B, Champagne FA, Higgins ET | PloS one | 24376721 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24376721 |
Maternal modulation of paternal effects on offspring development. | Mashoodh R, Habrylo IB, Gudsnuk KM, Pelle G, Champagne FA | Proceedings. Biological sciences | 29514964 | Proc Biol Sci | 2018 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/29514964 |
Sexual experience affects reproductive behavior and preoptic androgen receptors in male mice. | Swaney WT, Dubose BN, Curley JP, Champagne FA | Hormones and behavior | 22266118 | Horm Behav | 2012 Apr | https://www.ncbi.nlm.nih.gov/pubmed/22266118 |
Evidence for individual differences in regulatory focus in rats, Rattus norvegicus. | Franks B, Higgins ET, Champagne FA | Journal of comparative psychology (Washington, D.C. : 1983) | 22390620 | J Comp Psychol | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/22390620 |
Epigenetic influence of social experiences across the lifespan. | Champagne FA | Developmental psychobiology | 20175106 | Dev Psychobiol | 2010 May | https://www.ncbi.nlm.nih.gov/pubmed/20175106 |
Social influences on neurobiology and behavior: epigenetic effects during development. | Curley JP, Jensen CL, Mashoodh R, Champagne FA | Psychoneuroendocrinology | 20650569 | Psychoneuroendocrinology | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/20650569 |
Epigenetics and the origins of paternal effects. | Curley JP, Mashoodh R, Champagne FA | Hormones and behavior | 20620140 | Horm Behav | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20620140 |
Epigenetic mechanisms and the transgenerational effects of maternal care. | Champagne FA | Frontiers in neuroendocrinology | 18462782 | Front Neuroendocrinol | 2008 Jun | https://www.ncbi.nlm.nih.gov/pubmed/18462782 |
Maternal regulation of estrogen receptor alpha methylation. | Champagne FA, Curley JP | Current opinion in pharmacology | 18644464 | Curr Opin Pharmacol | 2008 Dec | https://www.ncbi.nlm.nih.gov/pubmed/18644464 |
Effects of maternal care on the development of midbrain dopamine pathways and reward-directed behavior in female offspring. | Peña CJ, Neugut YD, Calarco CA, Champagne FA | The European journal of neuroscience | 24446918 | Eur J Neurosci | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24446918 |
Epigenetic perspective on the developmental effects of bisphenol A. | Kundakovic M, Champagne FA | Brain, behavior, and immunity | 21333735 | Brain Behav Immun | 2011 Aug | https://www.ncbi.nlm.nih.gov/pubmed/21333735 |
DNA methylation of BDNF as a biomarker of early-life adversity. | Kundakovic M, Gudsnuk K, Herbstman JB, Tang D, Perera FP, Champagne FA | Proceedings of the National Academy of Sciences of the United States of America | 25385582 | Proc Natl Acad Sci U S A | 2015 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/25385582 |
Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. | Tang G, Gudsnuk K, Kuo SH, Cotrina ML, Rosoklija G, Sosunov A, Sonders MS, Kanter E, Castagna C, Yamamoto A, Yue Z, Arancio O, Peterson BS, Champagne F, Dwork AJ, Goldman J, Sulzer D | Neuron | 25155956 | Neuron | 2014 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/25155956 |
Neonatal overexpression of estrogen receptor-α alters midbrain dopamine neuron development and reverses the effects of low maternal care in female offspring. | Peña CJ, Champagne FA | Developmental neurobiology | 25044746 | Dev Neurobiol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25044746 |
Social enrichment during postnatal development induces transgenerational effects on emotional and reproductive behavior in mice. | Curley JP, Davidson S, Bateson P, Champagne FA | Frontiers in behavioral neuroscience | 19826497 | Front Behav Neurosci | 2009 | https://www.ncbi.nlm.nih.gov/pubmed/19826497 |
Parent-of-origin and trans-generational germline influences on behavioral development: the interacting roles of mothers, fathers, and grandparents. | Curley JP, Mashoodh R | Developmental psychobiology | 20373326 | Dev Psychobiol | 2010 May | https://www.ncbi.nlm.nih.gov/pubmed/20373326 |
Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways. | Monk C, Spicer J, Champagne FA | Development and psychopathology | 23062303 | Dev Psychopathol | 2012 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23062303 |
Epigenetic and Neurodevelopmental Perspectives on Variation in Parenting Behavior. | Jensen CL, Champagne FA | Parenting, science and practice | 23162380 | Parent Sci Pract | 2012 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/23162380 |
Maternal imprints and the origins of variation. | Champagne FA | Hormones and behavior | 21376726 | Horm Behav | 2011 Jun | https://www.ncbi.nlm.nih.gov/pubmed/21376726 |
Sex-specific and strain-dependent effects of early life adversity on behavioral and epigenetic outcomes. | Kundakovic M, Lim S, Gudsnuk K, Champagne FA | Frontiers in psychiatry | 23914177 | Front Psychiatry | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23914177 |
Developmental timing of the effects of maternal care on gene expression and epigenetic regulation of hormone receptor levels in female rats. | Peña CJ, Neugut YD, Champagne FA | Endocrinology | 24002038 | Endocrinology | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24002038 |
Sex-specific epigenetic disruption and behavioral changes following low-dose in utero bisphenol A exposure. | Kundakovic M, Gudsnuk K, Franks B, Madrid J, Miller RL, Perera FP, Champagne FA | Proceedings of the National Academy of Sciences of the United States of America | 23716699 | Proc Natl Acad Sci U S A | 2013 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/23716699 |
Developmental effects of serotonin 1A autoreceptors on anxiety and social behavior. | Donaldson ZR, Piel DA, Santos TL, Richardson-Jones J, Leonardo ED, Beck SG, Champagne FA, Hen R | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 23907404 | Neuropsychopharmacology | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23907404 |
Implications of temporal variation in maternal care for the prediction of neurobiological and behavioral outcomes in offspring. | Jensen Peña C, Champagne FA | Behavioral neuroscience | 23398440 | Behav Neurosci | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23398440 |
Interplay between social experiences and the genome: epigenetic consequences for behavior. | Champagne FA | Advances in genetics | 22902125 | Adv Genet | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22902125 |
Epigenetic effects of prenatal stress on 11β-hydroxysteroid dehydrogenase-2 in the placenta and fetal brain. | Jensen Peña C, Monk C, Champagne FA | PloS one | 22761903 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22761903 |
Epigenetics and developmental plasticity across species. | Champagne FA | Developmental psychobiology | 22711291 | Dev Psychobiol | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22711291 |
A theoretically based model of rat personality with implications for welfare. | Franks B, Higgins ET, Champagne FA | PloS one | 24755737 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24755737 |
Paternal social enrichment effects on maternal behavior and offspring growth. | Mashoodh R, Franks B, Curley JP, Champagne FA | Proceedings of the National Academy of Sciences of the United States of America | 23045657 | Proc Natl Acad Sci U S A | 2012 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/23045657 |
Variation in maternal and anxiety-like behavior associated with discrete patterns of oxytocin and vasopressin 1a receptor density in the lateral septum. | Curley JP, Jensen CL, Franks B, Champagne FA | Hormones and behavior | 22300676 | Horm Behav | 2012 Mar | https://www.ncbi.nlm.nih.gov/pubmed/22300676 |
Sex-specific effects of chronic paternal stress on offspring development are partially mediated via mothers. | Mashoodh R, Habrylo IB, Gudsnuk K, Champagne FA | Hormones and behavior | 37062113 | Horm Behav | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37062113 |
Obstructive sleep apnea screening in pregnancy, perinatal outcomes, and impact of maternal obesity. | Olivarez SA, Ferres M, Antony K, Mattewal A, Maheshwari B, Sangi-Haghpeykar H, Aagaard-Tillery K | American journal of perinatology | 21480159 | Am J Perinatol | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21480159 |
Genetic and epigenetic influences associated with intrauterine growth restriction due to in utero tobacco exposure. | Suter M, Abramovici A, Aagaard-Tillery K | Pediatric endocrinology reviews : PER | 21150839 | Pediatr Endocrinol Rev | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/21150839 |
Environmental influences on epigenetic profiles. | Suter MA, Aagaard-Tillery KM | Seminars in reproductive medicine | 19711248 | Semin Reprod Med | 2009 Sep | https://www.ncbi.nlm.nih.gov/pubmed/19711248 |
Obstructive sleep apnea in pregnancy: reliability of prevalence and prediction estimates. | Antony KM, Agrawal A, Arndt ME, Murphy AM, Alapat PM, Guntupalli KK, Aagaard KM | Journal of perinatology : official journal of the California Perinatal Association | 24674980 | J Perinatol | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24674980 |
Association of adverse perinatal outcomes with screening measures of obstructive sleep apnea. | Antony KM, Agrawal A, Arndt ME, Murphy AM, Alapat PM, Guntupalli KK, Aagaard KM | Journal of perinatology : official journal of the California Perinatal Association | 24603455 | J Perinatol | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24603455 |
Evolutionary genetics and implications of small size and twinning in callitrichine primates. | Harris RA, Tardif SD, Vinar T, Wildman DE, Rutherford JN, Rogers J, Worley KC, Aagaard KM | Proceedings of the National Academy of Sciences of the United States of America | 24379383 | Proc Natl Acad Sci U S A | 2014 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/24379383 |
Alterations in expression of imprinted genes from the H19/IGF2 loci in a multigenerational model of intrauterine growth restriction (IUGR). | Gonzalez-Rodriguez P, Cantu J, O'Neil D, Seferovic MD, Goodspeed DM, Suter MA, Aagaard KM | American journal of obstetrics and gynecology | 26880735 | Am J Obstet Gynecol | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26880735 |
Maternal smoking as a model for environmental epigenetic changes affecting birthweight and fetal programming. | Suter MA, Anders AM, Aagaard KM | Molecular human reproduction | 23139402 | Mol Hum Reprod | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23139402 |
Maternal tobacco use is associated with increased markers of oxidative stress in the placenta. | Sbrana E, Suter MA, Abramovici AR, Hawkins HK, Moss JE, Patterson L, Shope C, Aagaard-Tillery K | American journal of obstetrics and gynecology | 21803321 | Am J Obstet Gynecol | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21803321 |
Structural and transcriptomic response to antenatal corticosteroids in an Erk3-null mouse model of respiratory distress. | Pew BK, Harris RA, Sbrana E, Guaman MC, Shope C, Chen R, Meloche S, Aagaard K | American journal of obstetrics and gynecology | 27143398 | Am J Obstet Gynecol | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27143398 |
The placental membrane microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis. | Prince AL, Ma J, Kannan PS, Alvarez M, Gisslen T, Harris RA, Sweeney EL, Knox CL, Lambers DS, Jobe AH, Chougnet CA, Kallapur SG, Aagaard KM | American journal of obstetrics and gynecology | 26965447 | Am J Obstet Gynecol | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26965447 |
The early infant gut microbiome varies in association with a maternal high-fat diet. | Chu DM, Antony KM, Ma J, Prince AL, Showalter L, Moller M, Aagaard KM | Genome medicine | 27503374 | Genome Med | 2016 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/27503374 |
Geospatial analysis of food environment demonstrates associations with gestational diabetes. | Kahr MK, Suter MA, Ballas J, Ramin SM, Monga M, Lee W, Hu M, Shope CD, Chesnokova A, Krannich L, Griffin EN, Mastrobattista J, Dildy GA, Strehlow SL, Ramphul R, Hamilton WJ, Aagaard KM | American journal of obstetrics and gynecology | 26319053 | Am J Obstet Gynecol | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/26319053 |
In utero tobacco exposure epigenetically modifies placental CYP1A1 expression. | Suter M, Abramovici A, Showalter L, Hu M, Shope CD, Varner M, Aagaard-Tillery K | Metabolism: clinical and experimental | 20462615 | Metabolism | 2010 Oct | https://www.ncbi.nlm.nih.gov/pubmed/20462615 |
Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome. | Aagaard-Tillery KM, Grove K, Bishop J, Ke X, Fu Q, McKnight R, Lane RH | Journal of molecular endocrinology | 18515302 | J Mol Endocrinol | 2008 Aug | https://www.ncbi.nlm.nih.gov/pubmed/18515302 |
A maternal high-fat diet is accompanied by alterations in the fetal primate metabolome. | Cox J, Williams S, Grove K, Lane RH, Aagaard-Tillery KM | American journal of obstetrics and gynecology | 19733280 | Am J Obstet Gynecol | 2009 Sep | https://www.ncbi.nlm.nih.gov/pubmed/19733280 |
Epigenomics: maternal high-fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates. | Suter M, Bocock P, Showalter L, Hu M, Shope C, McKnight R, Grove K, Lane R, Aagaard-Tillery K | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 21097519 | FASEB J | 2011 Feb | https://www.ncbi.nlm.nih.gov/pubmed/21097519 |
Modulations in the offspring gut microbiome are refractory to postnatal synbiotic supplementation among juvenile primates. | Pace RM, Prince AL, Ma J, Belfort BDW, Harvey AS, Hu M, Baquero K, Blundell P, Takahashi D, Dean T, Kievit P, Sullivan EL, Friedman JE, Grove K, Aagaard KM | BMC microbiology | 29621980 | BMC Microbiol | 2018 Apr 5 | https://www.ncbi.nlm.nih.gov/pubmed/29621980 |
Conditional postnatal deletion of the neonatal murine hepatic circadian gene, Npas2, alters the gut microbiome following restricted feeding. | O'Neil DS, Stewart CJ, Chu DM, Goodspeed DM, Gonzalez-Rodriguez PJ, Shope CD, Aagaard KM | American journal of obstetrics and gynecology | 28373017 | Am J Obstet Gynecol | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28373017 |
A metagenomic approach to characterization of the vaginal microbiome signature in pregnancy. | Aagaard K, Riehle K, Ma J, Segata N, Mistretta TA, Coarfa C, Raza S, Rosenbaum S, Van den Veyver I, Milosavljevic A, Gevers D, Huttenhower C, Petrosino J, Versalovic J | PloS one | 22719832 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22719832 |
High-fat maternal diet during pregnancy persistently alters the offspring microbiome in a primate model. | Ma J, Prince AL, Bader D, Hu M, Ganu R, Baquero K, Blundell P, Alan Harris R, Frias AE, Grove KL, Aagaard KM | Nature communications | 24846660 | Nat Commun | 2014 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/24846660 |
The placenta harbors a unique microbiome. | Aagaard K, Ma J, Antony KM, Ganu R, Petrosino J, Versalovic J | Science translational medicine | 24848255 | Sci Transl Med | 2014 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/24848255 |
Dysregulation of Npas2 leads to altered metabolic pathways in a murine knockout model. | O'Neil D, Mendez-Figueroa H, Mistretta TA, Su C, Lane RH, Aagaard KM | Molecular genetics and metabolism | 24067359 | Mol Genet Metab | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24067359 |
The microbiome, parturition, and timing of birth: more questions than answers. | Prince AL, Antony KM, Chu DM, Aagaard KM | Journal of reproductive immunology | 24793619 | J Reprod Immunol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24793619 |
Obesity and the risk and detection of fetal malformations. | Racusin D, Stevens B, Campbell G, Aagaard KM | Seminars in perinatology | 22713503 | Semin Perinatol | 2012 Jun | https://www.ncbi.nlm.nih.gov/pubmed/22713503 |
Heritable IUGR and adult metabolic syndrome are reversible and associated with alterations in the metabolome following dietary supplementation of 1-carbon intermediates. | Seferovic MD, Goodspeed DM, Chu DM, Krannich LA, Gonzalez-Rodriguez PJ, Cox JE, Aagaard KM | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 25757570 | FASEB J | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25757570 |
The perinatal microbiome and pregnancy: moving beyond the vaginal microbiome. | Prince AL, Chu DM, Seferovic MD, Antony KM, Ma J, Aagaard KM | Cold Spring Harbor perspectives in medicine | 25775922 | Cold Spring Harb Perspect Med | 2015 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/25775922 |
Metagenomic profiling of placental tissue suggests DNA virus infection of the placenta is rare. | Witney AA, Aller S, Strang BL | The Journal of general virology | 34723784 | J Gen Virol | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34723784 |
Family history is a predictor of current preterm birth. | Koire A, Chu DM, Aagaard K | American journal of obstetrics & gynecology MFM | 33451608 | Am J Obstet Gynecol MFM | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33451608 |
Essential nutrient supplementation prevents heritable metabolic disease in multigenerational intrauterine growth-restricted rats. | Goodspeed D, Seferovic MD, Holland W, Mcknight RA, Summers SA, Branch DW, Lane RH, Aagaard KM | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 25395450 | FASEB J | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25395450 |
In utero exposure to a maternal high-fat diet alters the epigenetic histone code in a murine model. | Suter MA, Ma J, Vuguin PM, Hartil K, Fiallo A, Harris RA, Charron MJ, Aagaard KM | American journal of obstetrics and gynecology | 24793723 | Am J Obstet Gynecol | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24793723 |
Qualitative assessment of attitudes and knowledge on preterm birth in Malawi and within country framework of care. | Levison J, Nanthuru D, Chiudzu G, Kazembe PN, Phiri H, Ramin SM, Aagaard KM | BMC pregnancy and childbirth | 24690288 | BMC Pregnancy Childbirth | 2014 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/24690288 |
Animal models of epigenetic inheritance. | Bocock PN, Aagaard-Tillery KM | Seminars in reproductive medicine | 19711247 | Semin Reprod Med | 2009 Sep | https://www.ncbi.nlm.nih.gov/pubmed/19711247 |
Genome-wide array-based copy number profiling in human placentas from unexplained stillbirths. | Harris RA, Ferrari F, Ben-Shachar S, Wang X, Saade G, Van Den Veyver I, Facchinetti F, Aagaard-Tillery K | Prenatal diagnosis | 21732394 | Prenat Diagn | 2011 Oct | https://www.ncbi.nlm.nih.gov/pubmed/21732394 |
Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression. | Suter M, Ma J, Harris A, Patterson L, Brown KA, Shope C, Showalter L, Abramovici A, Aagaard-Tillery KM | Epigenetics | 21937876 | Epigenetics | 2011 Nov | https://www.ncbi.nlm.nih.gov/pubmed/21937876 |
A framework for human microbiome research. | Human Microbiome Project Consortium | Nature | 22699610 | Nature | 2012 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/22699610 |
Pharmacogenomics of maternal tobacco use: metabolic gene polymorphisms and risk of adverse pregnancy outcomes. | Aagaard-Tillery K, Spong CY, Thom E, Sibai B, Wendel G Jr, Wenstrom K, Samuels P, Simhan H, Sorokin Y, Miodovnik M, Meis P, O'Sullivan MJ, Conway D, Wapner RJ, Eunice Kennedy Shriver National Institute of Child Health, Human Development (NICHD) Maternal–Fetal Medicine Units Network (MFMU) | Obstetrics and gynecology | 20177288 | Obstet Gynecol | 2010 Mar | https://www.ncbi.nlm.nih.gov/pubmed/20177288 |
A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. | Suter MA, Chen A, Burdine MS, Choudhury M, Harris RA, Lane RH, Friedman JE, Grove KL, Tackett AJ, Aagaard KM | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 22982377 | FASEB J | 2012 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22982377 |
Early origins of adult disease: approaches for investigating the programmable epigenome in humans, nonhuman primates, and rodents. | Ganu RS, Harris RA, Collins K, Aagaard KM | ILAR journal | 23744969 | ILAR J | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23744969 |
Transcriptome profiling of microRNA by Next-Gen deep sequencing reveals known and novel miRNA species in the lipid fraction of human breast milk. | Munch EM, Harris RA, Mohammad M, Benham AL, Pejerrey SM, Showalter L, Hu M, Shope CD, Maningat PD, Gunaratne PH, Haymond M, Aagaard K | PloS one | 23418415 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23418415 |
Postweaning exposure to a high-fat diet is associated with alterations to the hepatic histone code in Japanese macaques. | Suter MA, Takahashi D, Grove KL, Aagaard KM | Pediatric research | 23788059 | Pediatr Res | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23788059 |
The Genboree Microbiome Toolset and the analysis of 16S rRNA microbial sequences. | Riehle K, Coarfa C, Jackson A, Ma J, Tandon A, Paithankar S, Raghuraman S, Mistretta TA, Saulnier D, Raza S, Diaz MA, Shulman R, Aagaard K, Versalovic J, Milosavljevic A | BMC bioinformatics | 23320832 | BMC Bioinformatics | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23320832 |
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The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location. | Liu I, Jiang L, Samuelsson ER, Marco Salas S, Beck A, Hack OA, Jeong D, Shaw ML, Englinger B, LaBelle J, Mire HM, Madlener S, Mayr L, Quezada MA, Trissal M, Panditharatna E, Ernst KJ, Vogelzang J, Gatesman TA, Halbert ME, Palova H, Pokorna P, Sterba J, Slaby O, Geyeregger R, Diaz A, Findlay IJ, Dun MD, Resnick A, Suvà ML, Jones DTW, Agnihotri S, Svedlund J, Koschmann C, Haberler C, Czech T, Slavc I, Cotter JA, Ligon KL, Alexandrescu S, Yung WKA, Arrillaga-Romany I, Gojo J, Monje M, Nilsson M, Filbin MG | Nature genetics | 36471067 | Nat Genet | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36471067 |
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma. | Panditharatna E, Marques JG, Wang T, Trissal MC, Liu I, Jiang L, Beck A, Groves A, Dharia NV, Li D, Hoffman SE, Kugener G, Shaw ML, Mire HM, Hack OA, Dempster JM, Lareau C, Dai L, Sigua LH, Quezada MA, Stanton AJ, Wyatt M, Kalani Z, Goodale A, Vazquez F, Piccioni F, Doench JG, Root DE, Anastas JN, Jones KL, Conway AS, Stopka S, Regan MS, Liang Y, Seo HS, Song K, Bashyal P, Jerome WP, Mathewson ND, Dhe-Paganon S, Suvà ML, Carcaboso AM, Lavarino C, Mora J, Nguyen QD, Ligon KL, Shi Y, Agnihotri S, Agar NYR, Stegmaier K, Stiles CD, Monje M, Golub TR, Qi J, Filbin MG | Cancer discovery | 36305736 | Cancer Discov | 2022 Dec 2 | https://www.ncbi.nlm.nih.gov/pubmed/36305736 |
Associations Between Brain Metabolites Measured With MR Spectroscopy and Head Impacts in High School American Football Athletes. | Liu Z, Dudley JA, Diekfuss JA, Ahmed N, Edmondson AD, Cecil KM, Yuan W, Zuleger TM, Slutsky-Ganesh AB, Barber Foss KD, Myer GD, Fleischer CC | Journal of magnetic resonance imaging : JMRI | 39177233 | J Magn Reson Imaging | 2025 Apr | https://www.ncbi.nlm.nih.gov/pubmed/39177233 |
Label-Free Chemically and Molecularly Selective Magnetic Resonance Imaging. | Wu T, Liu C, Thamizhchelvan AM, Fleischer C, Peng X, Liu G, Mao H | Chemical & biomedical imaging | 37235188 | Chem Biomed Imaging | 2023 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/37235188 |
An Update on MR Spectroscopy in Cancer Management: Advances in Instrumentation, Acquisition, and Analysis. | Martinez Luque E, Liu Z, Sung D, Goldberg RM, Agarwal R, Bhattacharya A, Ahmed NS, Allen JW, Fleischer CC | Radiology. Imaging cancer | 38578207 | Radiol Imaging Cancer | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38578207 |
Reply to "Letter to the Editor - Critical Omissions Compromise Internal Validity in Jugular Vein Compression Collar Studies". | Fleischer CC, authors of the original manuscript | Journal of magnetic resonance imaging : JMRI | 39506603 | J Magn Reson Imaging | 2025 May | https://www.ncbi.nlm.nih.gov/pubmed/39506603 |
Reversal of National Coverage Determination for MR Spectroscopy Increases Reimbursement Rates. | Fleischer CC, Lin AP, Allen JW | Radiology. Imaging cancer | 39212523 | Radiol Imaging Cancer | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39212523 |
Climate change and neurological diseases: report from the Hot Brain 2: Climate Change and Brain Health meeting, 2024. | Mills JD, Gulcebi MI, Allatt J, Amos A, Atkinson J, Berwick J, Clayton S, Dijk DJ, Doell KC, Ebi K, Fleischer CC, Hajat S, Howarth C, Jones O, Maslin M, Page L, Romanello M, Vanhala L, Sisodiya SM | BMJ neurology open | 39737344 | BMJ Neurol Open | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/39737344 |
BRAND: a platform for closed-loop experiments with deep network models. | Ali YH, Bodkin K, Rigotti-Thompson M, Patel K, Card NS, Bhaduri B, Nason-Tomaszewski SR, Mifsud DM, Hou X, Nicolas C, Allcroft S, Hochberg LR, Au Yong N, Stavisky SD, Miller LE, Brandman DM, Pandarinath C | Journal of neural engineering | 38579696 | J Neural Eng | 2024 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/38579696 |
Myomatrix arrays for high-definition muscle recording. | Chung B, Zia M, Thomas KA, Michaels JA, Jacob A, Pack A, Williams MJ, Nagapudi K, Teng LH, Arrambide E, Ouellette L, Oey N, Gibbs R, Anschutz P, Lu J, Wu Y, Kashefi M, Oya T, Kersten R, Mosberger AC, O'Connell S, Wang R, Marques H, Mendes AR, Lenschow C, Kondakath G, Kim JJ, Olson W, Quinn KN, Perkins P, Gatto G, Thanawalla A, Coltman S, Kim T, Smith T, Binder-Markey B, Zaback M, Thompson CK, Giszter S, Person A, Goulding M, Azim E, Thakor N, O'Connor D, Trimmer B, Lima SQ, Carey MR, Pandarinath C, Costa RM, Pruszynski JA, Bakir M, Sober SJ | bioRxiv : the preprint server for biology | 36865176 | bioRxiv | 2023 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/36865176 |
A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution. | Zhu F, Grier HA, Tandon R, Cai C, Agarwal A, Giovannucci A, Kaufman MT, Pandarinath C | Nature neuroscience | 36424431 | Nat Neurosci | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36424431 |
Diffusion-Based Generation of Neural Activity from Disentangled Latent Codes. | McCart JD, Sedler AR, Versteeg C, Mifsud D, Rigotti-Thompson M, Pandarinath C | ArXiv | 39130199 | ArXiv | 2024 Jul 30 | https://www.ncbi.nlm.nih.gov/pubmed/39130199 |
Identifying Distinct Neural Features between the Initial and Corrective Phases of Precise Reaching Using AutoLFADS. | Lee WH, Karpowicz BM, Pandarinath C, Rouse AG | The Journal of neuroscience : the official journal of the Society for Neuroscience | 38538142 | J Neurosci | 2024 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/38538142 |
Computation-through-Dynamics Benchmark: Simulated datasets and quality metrics for dynamical models of neural activity. | Versteeg C, McCart JD, Ostrow M, Zoltowski DM, Washington CB, Driscoll L, Codol O, Michaels JA, Linderman SW, Sussillo D, Pandarinath C | bioRxiv : the preprint server for biology | 39975240 | bioRxiv | 2025 Feb 20 | https://www.ncbi.nlm.nih.gov/pubmed/39975240 |
Estimating muscle activation from EMG using deep learning-based dynamical systems models. | Wimalasena LN, Braun JF, Keshtkaran MR, Hofmann D, Gallego JÁ, Alessandro C, Tresch MC, Miller LE, Pandarinath C | Journal of neural engineering | 35366649 | J Neural Eng | 2022 May 19 | https://www.ncbi.nlm.nih.gov/pubmed/35366649 |
High-performance neural population dynamics modeling enabled by scalable computational infrastructure. | Patel AN, Sedler AR, Huang J, Pandarinath C, Gilja V | Journal of open source software | 37520691 | J Open Source Softw | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37520691 |
Myomatrix arrays for high-definition muscle recording. | Chung B, Zia M, Thomas KA, Michaels JA, Jacob A, Pack A, Williams MJ, Nagapudi K, Teng LH, Arrambide E, Ouellette L, Oey N, Gibbs R, Anschutz P, Lu J, Wu Y, Kashefi M, Oya T, Kersten R, Mosberger AC, O'Connell S, Wang R, Marques H, Mendes AR, Lenschow C, Kondakath G, Kim JJ, Olson W, Quinn KN, Perkins P, Gatto G, Thanawalla A, Coltman S, Kim T, Smith T, Binder-Markey B, Zaback M, Thompson CK, Giszter S, Person A, Goulding M, Azim E, Thakor N, O'Connor D, Trimmer B, Lima SQ, Carey MR, Pandarinath C, Costa RM, Pruszynski JA, Bakir M, Sober SJ | eLife | 38113081 | Elife | 2023 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/38113081 |
Expressive dynamics models with nonlinear injective readouts enable reliable recovery of latent features from neural activity. | Versteeg C, Sedler AR, McCart JD, Pandarinath C | ArXiv | 37744459 | ArXiv | 2023 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/37744459 |
A large-scale neural network training framework for generalized estimation of single-trial population dynamics. | Keshtkaran MR, Sedler AR, Chowdhury RH, Tandon R, Basrai D, Nguyen SL, Sohn H, Jazayeri M, Miller LE, Pandarinath C | Nature methods | 36443486 | Nat Methods | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36443486 |
Spinal interneuron population dynamics underlying flexible pattern generation. | Wimalasena LN, Pandarinath C, Yong NA | bioRxiv : the preprint server for biology | 38948833 | bioRxiv | 2024 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/38948833 |
Expressive architectures enhance interpretability of dynamics-based neural population models. | Sedler AR, Versteeg C, Pandarinath C | Neurons, behavior, data analysis, and theory | 38699512 | Neuron Behav Data Anal Theory | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/38699512 |
Reducing power requirements for high-accuracy decoding in iBCIs. | Karpowicz BM, Bhaduri B, Nason-Tomaszewski SR, Jacques BG, Ali YH, Flint RD, Bechefsky PH, Hochberg LR, AuYong N, Slutzky MW, Pandarinath C | Journal of neural engineering | 39423832 | J Neural Eng | 2024 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/39423832 |
A DRG genetic toolkit reveals molecular, morphological, and functional diversity of somatosensory neuron subtypes. | Qi L, Iskols M, Shi D, Reddy P, Walker C, Lezgiyeva K, Voisin T, Pawlak M, Kuchroo VK, Chiu I, Ginty DD, Sharma N | bioRxiv : the preprint server for biology | 37131664 | bioRxiv | 2023 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/37131664 |
DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon. | Wolfson RL, Abdelaziz A, Rankin G, Kushner S, Qi L, Mazor O, Choi S, Sharma N, Ginty DD | Cell | 37541195 | Cell | 2023 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/37541195 |
A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes. | Qi L, Iskols M, Shi D, Reddy P, Walker C, Lezgiyeva K, Voisin T, Pawlak M, Kuchroo VK, Chiu IM, Ginty DD, Sharma N | Cell | 38442711 | Cell | 2024 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/38442711 |
Activity-dependent development of the body's touch receptors. | Santiago C, Sharma N, Africawala N, Siegrist J, Handler A, Tasnim A, Anjum R, Turecek J, Lehnert BP, Renauld S, Nolan-Tamariz M, Iskols M, Magee AR, Paradis S, Ginty DD | bioRxiv : the preprint server for biology | 37790437 | bioRxiv | 2023 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/37790437 |
Zebrafish: an underutilized tool for discovery in host-microbe interactions. | Stream A, Madigan CA | Trends in immunology | 35527182 | Trends Immunol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35527182 |
Inference of network connectivity from temporally binned spike trains. | Vareberg AD, Bok I, Eizadi J, Ren X, Hai A | Journal of neuroscience methods | 38309313 | J Neurosci Methods | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38309313 |
Wireless in vivo Recording of Cortical Activity by an Ion-Sensitive Field Effect Transistor. | Bhatt S, Masterson E, Zhu T, Eizadi J, George J, Graupe N, Vareberg A, Phillips J, Bok I, Dwyer M, Ashtiani A, Hai A | bioRxiv : the preprint server for biology | 36711824 | bioRxiv | 2023 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/36711824 |
Enhanced magnetic transduction of neuronal activity by nanofabricated inductors quantified via finite element analysis. | Phillips J, Glodowski M, Gokhale Y, Dwyer M, Ashtiani A, Hai A | Journal of neural engineering | 35705065 | J Neural Eng | 2022 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/35705065 |
In silico assessment of electrophysiological neuronal recordings mediated by magnetoelectric nanoparticles. | Bok I, Haber I, Qu X, Hai A | Scientific reports | 35589877 | Sci Rep | 2022 May 19 | https://www.ncbi.nlm.nih.gov/pubmed/35589877 |
Direct observation of NMR transverse relaxation in nanopatterned clusters of iron oxide particles. | Bok I, Rauch B, Ashtiani A, Hai A | Magnetic resonance in medicine | 37867452 | Magn Reson Med | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/37867452 |
Wireless agents for brain recording and stimulation modalities. | Bok I, Vareberg A, Gokhale Y, Bhatt S, Masterson E, Phillips J, Zhu T, Ren X, Hai A | Bioelectronic medicine | 37726851 | Bioelectron Med | 2023 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/37726851 |
Wireless in vivo Recording of Cortical Activity by an Ion-Sensitive Field Effect Transistor. | Bhatt S, Masterson E, Zhu T, Eizadi J, George J, Graupe N, Vareberg A, Phillips J, Bok I, Dwyer M, Ashtiani A, Hai A | Sensors and actuators. B, Chemical | 36970106 | Sens Actuators B Chem | 2023 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/36970106 |
Stimulation-mediated reverse engineering of silent neural networks. | Ren X, Bok I, Vareberg A, Hai A | Journal of neurophysiology | 37222450 | J Neurophysiol | 2023 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/37222450 |
Magnetic Detection of Neural Activity by Nanocoil Transducers. | Bok I, Phillips J, Zhu T, Lu J, Detienne E, Lima EA, Weiss BP, Jasanoff A, Hai A | Nano letters | 39319575 | Nano Lett | 2024 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/39319575 |
β-Adrenergic Signaling Promotes Morphological Maturation of Astrocytes in Female Mice. | Rosenberg MF, Godoy MI, Wade SD, Paredes MF, Zhang Y, Molofsky AV | The Journal of neuroscience : the official journal of the Society for Neuroscience | 37845031 | J Neurosci | 2023 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/37845031 |
Implications of Extended Inhibitory Neuron Development. | Kim JY, Paredes MF | International journal of molecular sciences | 34066025 | Int J Mol Sci | 2021 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/34066025 |
The development and evolution of inhibitory neurons in primate cerebrum. | Schmitz MT, Sandoval K, Chen CP, Mostajo-Radji MA, Seeley WW, Nowakowski TJ, Ye CJ, Paredes MF, Pollen AA | Nature | 35322231 | Nature | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35322231 |
Interneuron Origins in the Embryonic Porcine Medial Ganglionic Eminence. | Casalia ML, Li T, Ramsay H, Ross PJ, Paredes MF, Baraban SC | The Journal of neuroscience : the official journal of the Society for Neuroscience | 33637558 | J Neurosci | 2021 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/33637558 |
Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus. | Sorrells SF, Paredes MF, Zhang Z, Kang G, Pastor-Alonso O, Biagiotti S, Page CE, Sandoval K, Knox A, Connolly A, Huang EJ, Garcia-Verdugo JM, Oldham MC, Yang Z, Alvarez-Buylla A | The Journal of neuroscience : the official journal of the Society for Neuroscience | 33762407 | J Neurosci | 2021 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/33762407 |
A CRISPR-engineered isogenic model of the 22q11.2 A-B syndromic deletion. | Paranjape N, Lin YT, Flores-Ramirez Q, Sarin V, Johnson AB, Chu J, Paredes M, Wiita AP | Scientific reports | 37169815 | Sci Rep | 2023 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/37169815 |
Amplification of human interneuron progenitors promotes brain tumors and neurological defects. | Eichmüller OL, Corsini NS, Vértesy Á, Morassut I, Scholl T, Gruber VE, Peer AM, Chu J, Novatchkova M, Hainfellner JA, Paredes MF, Feucht M, Knoblich JA | Science (New York, N.Y.) | 35084981 | Science | 2022 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/35084981 |
Large-scale neurophysiology and single-cell profiling in human neuroscience. | Lee AT, Chang EF, Paredes MF, Nowakowski TJ | Nature | 38898291 | Nature | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38898291 |
Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy. | Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V | Neurology. Genetics | 38586598 | Neurol Genet | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38586598 |
The information bottleneck as a principle underlying multi-area cortical representations during decision-making. | Kleinman M, Wang T, Xiao D, Feghhi E, Lee K, Carr N, Li Y, Hadidi N, Chandrasekaran C, Kao JC | bioRxiv : the preprint server for biology | 37502862 | bioRxiv | 2025 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/37502862 |
An artificial intelligence that increases simulated brain-computer interface performance. | Olsen S, Zhang J, Liang KF, Lam M, Riaz U, Kao JC | Journal of neural engineering | 33978599 | J Neural Eng | 2021 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/33978599 |
Measurement, manipulation and modeling of brain-wide neural population dynamics. | Shenoy KV, Kao JC | Nature communications | 33504773 | Nat Commun | 2021 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/33504773 |
Non-invasive brain-machine interface control with artificial intelligence copilots. | Lee JY, Lee S, Mishra A, Yan X, McMahan B, Gaisford B, Kobashigawa C, Qu M, Xie C, Kao JC | bioRxiv : the preprint server for biology | 39416032 | bioRxiv | 2024 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/39416032 |
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease. | Koide M, Harraz OF, Dabertrand F, Longden TA, Ferris HR, Wellman GC, Hill-Eubanks DC, Greenstein AS, Nelson MT | The Journal of clinical investigation | 34351870 | J Clin Invest | 2021 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/34351870 |
Brain capillary pericytes are metabolic sentinels that control blood flow through a K(ATP) channel-dependent energy switch. | Hariharan A, Robertson CD, Garcia DCG, Longden TA | Cell reports | 36577387 | Cell Rep | 2022 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/36577387 |
Pathologically Entangled: Brain Trauma-Evoked ROS Imbalance Disrupts Kir Channel Function in Distant Peripheral Vessels. | Weir N, Longden TA | Function (Oxford, England) | 35330675 | Function (Oxf) | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/35330675 |
Electro-metabolic signaling. | Longden TA, Lederer WJ | The Journal of general physiology | 38197953 | J Gen Physiol | 2024 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/38197953 |
Pericyte Electrical Signalling and Brain Haemodynamics. | Longden TA, Isaacs D | Basic & clinical pharmacology & toxicology | 40159653 | Basic Clin Pharmacol Toxicol | 2025 May | https://www.ncbi.nlm.nih.gov/pubmed/40159653 |
Pericytes and the Control of Blood Flow in Brain and Heart. | Longden TA, Zhao G, Hariharan A, Lederer WJ | Annual review of physiology | 36763972 | Annu Rev Physiol | 2023 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/36763972 |
Local IP(3) receptor-mediated Ca(2+) signals compound to direct blood flow in brain capillaries. | Longden TA, Mughal A, Hennig GW, Harraz OF, Shui B, Lee FK, Lee JC, Reining S, Kotlikoff MI, König GM, Kostenis E, Hill-Eubanks D, Nelson MT | Science advances | 34290098 | Sci Adv | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34290098 |
Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow. | Lim XR, Abd-Alhaseeb MM, Ippolito M, Koide M, Senatore AJ, Plante C, Hariharan A, Weir N, Longden TA, Laprade KA, Stafford JM, Ziemens D, Schwaninger M, Wenzel J, Postnov DD, Harraz OF | Nature communications | 39375369 | Nat Commun | 2024 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/39375369 |
The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes. | Hariharan A, Weir N, Robertson C, He L, Betsholtz C, Longden TA | Frontiers in cellular neuroscience | 33390906 | Front Cell Neurosci | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33390906 |
K(ATP) channel-dependent electrical signaling links capillary pericytes to arterioles during neurovascular coupling. | Isaacs D, Xiang L, Hariharan A, Longden TA | Proceedings of the National Academy of Sciences of the United States of America | 39630860 | Proc Natl Acad Sci U S A | 2024 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/39630860 |
Towards Cell and Subtype Resolved Functional Organization: Mouse as a Model for the Cortical Control of Movement. | Warriner CL, Fageiry SK, Carmona LM, Miri A | Neuroscience | 32771500 | Neuroscience | 2020 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/32771500 |
Motor cortical influence relies on task-specific activity covariation. | Warriner CL, Fageiry S, Saxena S, Costa RM, Miri A | Cell reports | 36170841 | Cell Rep | 2022 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/36170841 |
Tetris in the Nervous System: What Principles of Neuronal Tiling Can Tell Us About How Glia Play the Game. | DeSantis DF, Smith CJ | Frontiers in cellular neuroscience | 34512272 | Front Cell Neurosci | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34512272 |
A Subset of Oligodendrocyte Lineage Cells Interact With the Developing Dorsal Root Entry Zone During Its Genesis. | Green LA, Gallant RM, Brandt JP, Nichols EL, Smith CJ | Frontiers in cellular neuroscience | 35734217 | Front Cell Neurosci | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35734217 |
The embryonic zebrafish brain is seeded by a lymphatic-dependent population of mrc1(+) microglia precursors. | Green LA, O'Dea MR, Hoover CA, DeSantis DF, Smith CJ | Nature neuroscience | 35710983 | Nat Neurosci | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35710983 |
Functional Regeneration of the Sensory Root via Axonal Invasion. | Nichols EL, Smith CJ | Cell reports | 31914401 | Cell Rep | 2020 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/31914401 |
Microglia cannibalism and efferocytosis leads to shorter lifespans of developmental microglia. | Gordon H, Schafer ZT, Smith CJ | PLoS biology | 39475879 | PLoS Biol | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39475879 |
Microglia cannibalism and efferocytosis leads to shorter lifespans of developmental microglia. | Gordon H, Schafer Z, Smith CJ | bioRxiv : the preprint server for biology | 36993267 | bioRxiv | 2024 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/36993267 |
An ultrastructural map of a spinal sensorimotor circuit reveals the potential of astroglial modulation. | Koh ZM, Arceo RA, Hammer J, Chau K, Light SEW, Dolojan A, Januszewski M, Svara F, Smith CJ | bioRxiv : the preprint server for biology | 40093104 | bioRxiv | 2025 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/40093104 |
Piezo1-mediated spontaneous calcium transients in satellite glia impact dorsal root ganglia development. | Brandt JP, Smith CJ | PLoS biology | 37747915 | PLoS Biol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37747915 |
Pioneer Axons Utilize a Dcc Signaling-Mediated Invasion Brake to Precisely Complete Their Pathfinding Odyssey. | Kikel-Coury NL, Green LA, Nichols EL, Zellmer AM, Pai S, Hedlund SA, Marsden KC, Smith CJ | The Journal of neuroscience : the official journal of the Society for Neuroscience | 34131031 | J Neurosci | 2021 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/34131031 |
Identification of astroglia-like cardiac nexus glia that are critical regulators of cardiac development and function. | Kikel-Coury NL, Brandt JP, Correia IA, O'Dea MR, DeSantis DF, Sterling F, Vaughan K, Ozcebe G, Zorlutuna P, Smith CJ | PLoS biology | 34793438 | PLoS Biol | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34793438 |
Evolutionarily conserved concepts in glial cell biology. | Smith CJ | Current opinion in neurobiology | 36577179 | Curr Opin Neurobiol | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36577179 |
Androgen Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. | Ghazizadeh Z, Majd H, Richter M, Samuel R, Zekavat SM, Asgharian H, Farahvashi S, Kalantari A, Ramirez J, Zhao H, Natarajan P, Goodarzi H, Fattahi F | bioRxiv : the preprint server for biology | 32511360 | bioRxiv | 2020 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/32511360 |
A call for a unified and multimodal definition of cellular identity in the enteric nervous system. | Majd H, Cesiulis A, Samuel RM, Richter MN, Elder N, Guyer RA, Hao MM, Stamp LA, Goldstein AM, Fattahi F | bioRxiv : the preprint server for biology | 38293133 | bioRxiv | 2024 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/38293133 |
Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy. | Majd H, Amin S, Ghazizadeh Z, Cesiulis A, Arroyo E, Lankford K, Majd A, Farahvashi S, Chemel AK, Okoye M, Scantlen MD, Tchieu J, Calder EL, Le Rouzic V, Shibata B, Arab A, Goodarzi H, Pasternak G, Kocsis JD, Chen S, Studer L, Fattahi F | Cell stem cell | 37146583 | Cell Stem Cell | 2023 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/37146583 |
Modeling enteric glia development, physiology and disease using human pluripotent stem cells. | Scantlen MD, Majd H, Fattahi F | Neuroscience letters | 37315730 | Neurosci Lett | 2023 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/37315730 |
Combined GWAS and single cell transcriptomics uncover the underlying genes and cell types in disorders of gut-brain interaction. | Majd A, Richter MN, Samuel RM, Cesiulis A, Ghazizadeh Z, Wang J, Fattahi F | medRxiv : the preprint server for health sciences | 37333423 | medRxiv | 2023 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/37333423 |
Stem Cell-Based Models for Studying the Effects of Cancer and Cancer Therapies on the Peripheral Nervous System. | Richter MN, Fattahi F | Advanced biology | 35666079 | Adv Biol (Weinh) | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/35666079 |
Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a interneurons. | Elder NH, Majd A, Bulger EA, Samuel RM, Zholudeva LV, McDevitt TC, Fattahi F | bioRxiv : the preprint server for biology | 39677634 | bioRxiv | 2024 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/39677634 |
Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. | Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F | Cell stem cell | 33232663 | Cell Stem Cell | 2020 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/33232663 |
Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma. | Samuel RM, Navickas A, Maynard A, Gaylord EA, Garcia K, Bhat S, Majd H, Richter MN, Elder N, Le D, Nguyen P, Shibata B, Llabata ML, Selleri L, Laird DJ, Darmanis S, Goodarzi H, Fattahi F | bioRxiv : the preprint server for biology | 36945537 | bioRxiv | 2023 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/36945537 |
TWISP: A Transgenic Worm for Interrogating Signal Propagation in C. elegans. | Sharma AK, Randi F, Kumar S, Dvali S, Leifer AM | bioRxiv : the preprint server for biology | 37577580 | bioRxiv | 2023 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/37577580 |
A high-throughput method to deliver targeted optogenetic stimulation to moving C. elegans populations. | Liu M, Kumar S, Sharma AK, Leifer AM | PLoS biology | 35089912 | PLoS Biol | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/35089912 |
Light evokes stereotyped global brain dynamics in Caenorhabditis elegans. | Gauthey W, Randi F, Sharma AK, Kumar S, Leifer AM | Current biology : CB | 38194919 | Curr Biol | 2024 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/38194919 |
Measuring and modeling whole-brain neural dynamics in Caenorhabditis elegans. | Randi F, Leifer AM | Current opinion in neurobiology | 33279794 | Curr Opin Neurobiol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33279794 |
An inhibitory acetylcholine receptor gates context dependent mechanosensory processing in C. elegans. | Kumar S, Sharma AK, Leifer AM | bioRxiv : the preprint server for biology | 38585821 | bioRxiv | 2024 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/38585821 |
Inhibitory feedback from the motor circuit gates mechanosensory processing in Caenorhabditis elegans. | Kumar S, Sharma AK, Tran A, Liu M, Leifer AM | PLoS biology | 37733772 | PLoS Biol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37733772 |
Continuous odor profile monitoring to study olfactory navigation in small animals. | Chen KS, Wu R, Gershow MH, Leifer AM | eLife | 37489570 | Elife | 2023 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/37489570 |
An inhibitory acetylcholine receptor gates context-dependent mechanosensory processing in C. elegans. | Kumar S, Sharma AK, Leifer AM | iScience | 39381742 | iScience | 2024 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/39381742 |
Diverging network architecture of the C. elegans connectome and signaling network. | Dvali S, Seguin C, Betzel R, Leifer AM | ArXiv | 39764398 | ArXiv | 2024 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/39764398 |
Large-scale neural recordings call for new insights to link brain and behavior. | Urai AE, Doiron B, Leifer AM, Churchland AK | Nature neuroscience | 34980926 | Nat Neurosci | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34980926 |
Neural signal propagation atlas of Caenorhabditis elegans. | Randi F, Sharma AK, Dvali S, Leifer AM | Nature | 37914938 | Nature | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37914938 |
TWISP: a transgenic worm for interrogating signal propagation in Caenorhabditis elegans. | Sharma AK, Randi F, Kumar S, Dvali S, Leifer AM | Genetics | 38733622 | Genetics | 2024 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/38733622 |
Nonequilibrium Green's Functions for Functional Connectivity in the Brain. | Randi F, Leifer AM | Physical review letters | 33798383 | Phys Rev Lett | 2021 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/33798383 |
Correcting motion induced fluorescence artifacts in two-channel neural imaging. | Creamer MS, Chen KS, Leifer AM, Pillow JW | PLoS computational biology | 36170268 | PLoS Comput Biol | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36170268 |
Adrenergic C1 neurons enhance anxiety via projections to PAG. | Fernández-Peña C, Pace RL, Fernando LM, Pittman BG, Schwarz LA | bioRxiv : the preprint server for biology | 39314285 | bioRxiv | 2024 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/39314285 |
A Novel Single Vector Intersectional AAV Strategy for Interrogating Cellular Diversity and Brain Function. | Hughes AC, Pollard BG, Xu B, Gammons JW, Chapman P, Bikoff JB, Schwarz LA | bioRxiv : the preprint server for biology | 36798174 | bioRxiv | 2023 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/36798174 |
A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function. | Hughes AC, Pittman BG, Xu B, Gammons JW, Webb CM, Nolen HG, Chapman P, Bikoff JB, Schwarz LA | Nature neuroscience | 38802592 | Nat Neurosci | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38802592 |
The chromatin remodeler ISWI acts during Drosophila development to regulate adult sleep. | Gong NN, Dilley LC, Williams CE, Moscato EH, Szuperak M, Wang Q, Jensen M, Girirajan S, Tan TY, Deardorff MA, Li D, Song Y, Kayser MS | Science advances | 33597246 | Sci Adv | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33597246 |
Synaptic dysfunction connects autism spectrum disorder and sleep disturbances: A perspective from studies in model organisms. | Doldur-Balli F, Imamura T, Veatch OJ, Gong NN, Lim DC, Hart MP, Abel T, Kayser MS, Brodkin ES, Pack AI | Sleep medicine reviews | 35158305 | Sleep Med Rev | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35158305 |
Pathogenic variants in SMARCA5, a chromatin remodeler, cause a range of syndromic neurodevelopmental features. | Li D, Wang Q, Gong NN, Kurolap A, Feldman HB, Boy N, Brugger M, Grand K, McWalter K, Guillen Sacoto MJ, Wakeling E, Hurst J, March ME, Bhoj EJ, Nowaczyk MJM, Gonzaga-Jauregui C, Mathew M, Dava-Wala A, Siemon A, Bartholomew D, Huang Y, Lee H, Martinez-Agosto JA, Schwaibold EMC, Brunet T, Choukair D, Pais LS, White SM, Christodoulou J, Brown D, Lindstrom K, Grebe T, Tiosano D, Kayser MS, Tan TY, Deardorff MA, Song Y, Hakonarson H | Science advances | 33980485 | Sci Adv | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33980485 |
Intrinsic maturation of sleep output neurons regulates sleep ontogeny in Drosophila. | Gong NN, Luong HNB, Dang AH, Mainwaring B, Shields E, Schmeckpeper K, Bonasio R, Kayser MS | Current biology : CB | 35985328 | Curr Biol | 2022 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/35985328 |
Social Behavioral Deficits with Loss of Neurofibromin Emerge from Peripheral Chemosensory Neuron Dysfunction. | Moscato EH, Dubowy C, Walker JA, Kayser MS | Cell reports | 32640222 | Cell Rep | 2020 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/32640222 |
Developmental emergence of sleep rhythms enables long-term memory in Drosophila. | Poe AR, Zhu L, Szuperak M, McClanahan PD, Anafi RC, Scholl B, Thum AS, Cavanaugh DJ, Kayser MS | Science advances | 37683005 | Sci Adv | 2023 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/37683005 |
Identification of a molecular basis for the juvenile sleep state. | Chakravarti Dilley L, Szuperak M, Gong NN, Williams CE, Saldana RL, Garbe DS, Syed MH, Jain R, Kayser MS | eLife | 32202500 | Elife | 2020 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/32202500 |
Getting into rhythm: developmental emergence of circadian clocks and behaviors. | Poe AR, Mace KD, Kayser MS | The FEBS journal | 34375504 | FEBS J | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34375504 |
Quantitative imaging of sleep behavior in Caenorhabditis elegans and larval Drosophila melanogaster. | Churgin MA, Szuperak M, Davis KC, Raizen DM, Fang-Yen C, Kayser MS | Nature protocols | 30953041 | Nat Protoc | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30953041 |
Neurofibromin 1 regulates early developmental sleep in Drosophila. | Durkin J, Poe AR, Belfer SJ, Rodriguez A, Tang SH, Walker JA, Kayser MS | Neurobiology of sleep and circadian rhythms | 37593040 | Neurobiol Sleep Circadian Rhythms | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37593040 |
Stem cell-specific ecdysone signaling regulates the development and function of a Drosophila sleep homeostat. | Wani AR, Chowdhury B, Luong J, Chaya GM, Patel K, Isaacman-Beck J, Shafer O, Kayser MS, Syed MH | bioRxiv : the preprint server for biology | 37873323 | bioRxiv | 2023 Oct 2 | https://www.ncbi.nlm.nih.gov/pubmed/37873323 |
Energetic Demands Regulate Sleep-Wake Rhythm Circuit Development. | Poe AR, Zhu L, Tang SH, Valencia E, Kayser MS | bioRxiv : the preprint server for biology | 37786713 | bioRxiv | 2024 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/37786713 |
Stem cell-specific ecdysone signaling regulates the development of dorsal fan-shaped body neurons and sleep homeostasis. | Wani AR, Chowdhury B, Luong J, Chaya GM, Patel K, Isaacman-Beck J, Kayser MS, Syed MH | Current biology : CB | 39383867 | Curr Biol | 2024 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/39383867 |
The CHD8/CHD7/Kismet family links blood-brain barrier glia and serotonin to ASD-associated sleep defects. | Coll-Tané M, Gong NN, Belfer SJ, van Renssen LV, Kurtz-Nelson EC, Szuperak M, Eidhof I, van Reijmersdal B, Terwindt I, Durkin J, Verheij MMM, Kim CN, Hudac CM, Nowakowski TJ, Bernier RA, Pillen S, Earl RK, Eichler EE, Kleefstra T, Kayser MS, Schenck A | Science advances | 34088660 | Sci Adv | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34088660 |
Starvation resistance is associated with developmentally specified changes in sleep, feeding and metabolic rate. | Brown EB, Slocumb ME, Szuperak M, Kerbs A, Gibbs AG, Kayser MS, Keene AC | The Journal of experimental biology | 30606795 | J Exp Biol | 2019 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/30606795 |
Energetic demands regulate sleep-wake rhythm circuit development. | Poe AR, Zhu L, Tang SH, Valencia E, Kayser MS | eLife | 39037919 | Elife | 2024 Jul 22 | https://www.ncbi.nlm.nih.gov/pubmed/39037919 |
Stem Cell Aging? Blame It on the Niche. | Morrow CS, Moore DL | Cell stem cell | 30849364 | Cell Stem Cell | 2019 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/30849364 |
Autofluorescence is a biomarker of neural stem cell activation state. | Morrow CS, Tweed K, Farhadova S, Walsh AJ, Lear BP, Roopra A, Risgaard RD, Klosa PC, Arndt ZP, Peterson ER, Chi MM, Harris AG, Skala MC, Moore DL | Cell stem cell | 38521057 | Cell Stem Cell | 2024 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/38521057 |
Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49(th) Annual Meeting of the American Aging Association. | Murphy ME, Narasimhan A, Adrian A, Kumar A, Green CL, Soto-Palma C, Henpita C, Camell C, Morrow CS, Yeh CY, Richardson CE, Hill CM, Moore DL, Lamming DW, McGregor ER, Simmons HA, Pak HH, Bai H, Denu JM, Clark J, Simcox J, Chittimalli K, Dahlquist K, Lee KA, Calubag M, Bouska M, Yousefzadeh MJ, Sonsalla M, Babygirija R, Yuan R, Tsuji T, Rhoads T, Menon V, Jarajapu YP, Zhu Y | GeroScience | 34714522 | Geroscience | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34714522 |
Adult fibroblasts use aggresomes only in distinct cell-states. | Morrow CS, Arndt ZP, Klosa PC, Peng B, Zewdie EY, Benayoun BA, Moore DL | Scientific reports | 36056070 | Sci Rep | 2022 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/36056070 |
Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit. | Morrow CS, Porter TJ, Xu N, Arndt ZP, Ako-Asare K, Heo HJ, Thompson EAN, Moore DL | Cell stem cell | 32109376 | Cell Stem Cell | 2020 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/32109376 |
Vimentin's side gig: Regulating cellular proteostasis in mammalian systems. | Morrow CS, Moore DL | Cytoskeleton (Hoboken, N.J.) | 33190414 | Cytoskeleton (Hoboken) | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33190414 |
Neural stem cell metabolism revisited: a critical role for mitochondria. | Scandella V, Petrelli F, Moore DL, Braun SMG, Knobloch M | Trends in endocrinology and metabolism: TEM | 37380501 | Trends Endocrinol Metab | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37380501 |
Fluorescent tagging of endogenous proteins with CRISPR/Cas9 in primary mouse neural stem cells. | Morrow CS, Porter TJ, Moore DL | STAR protocols | 34430917 | STAR Protoc | 2021 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/34430917 |
Low frequency independent components: Internal neuromarkers linking cortical LFPs to behavior. | Orellana V D, Donoghue JP, Vargas-Irwin CE | iScience | 38303697 | iScience | 2024 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/38303697 |
Auditory cues reveal intended movement information in middle frontal gyrus neuronal ensemble activity of a person with tetraplegia. | Hosman T, Hynes JB, Saab J, Wilcoxen KG, Buchbinder BR, Schmansky N, Cash SS, Eskandar EN, Simeral JD, Franco B, Kelemen J, Vargas-Irwin CE, Hochberg LR | Scientific reports | 33431994 | Sci Rep | 2021 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/33431994 |
The Precision of Place Fields Governs Their Fate across Epochs of Experience. | Chiu Y, Dong C, Krishnan S, Sheffield MEJ | eNeuro | 37973379 | eNeuro | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37973379 |
Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during navigation in familiar and novel environments. | Heer C, Sheffield M | eLife | 39504262 | Elife | 2024 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/39504262 |
Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during navigation in familiar and novel environments. | Heer CM, Sheffield MEJ | bioRxiv : the preprint server for biology | 38076843 | bioRxiv | 2024 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/38076843 |
Reward Expectation Reduces Representational Drift in the Hippocampus. | Krishnan S, Sheffield MEJ | bioRxiv : the preprint server for biology | 38187677 | bioRxiv | 2023 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/38187677 |
A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality. | Krishnan S, Dong C, Ratigan H, Morales-Rodriguez D, Cherian C, Sheffield M | bioRxiv : the preprint server for biology | 39651122 | bioRxiv | 2024 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/39651122 |
Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal. | Krishnan S, Heer C, Cherian C, Sheffield MEJ | Nature communications | 36333323 | Nat Commun | 2022 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/36333323 |
A thalamic-hippocampal CA1 signal for contextual fear memory suppression, extinction, and discrimination. | Ratigan HC, Krishnan S, Smith S, Sheffield MEJ | Nature communications | 37875465 | Nat Commun | 2023 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/37875465 |
Distinct place cell dynamics in CA1 and CA3 encode experience in new environments. | Dong C, Madar AD, Sheffield MEJ | Nature communications | 34016996 | Nat Commun | 2021 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/34016996 |
Direct Thalamic Inputs to Hippocampal CA1 Transmit a Signal That Suppresses Ongoing Contextual Fear Memory Retrieval. | Ratigan HC, Krishnan S, Smith S, Sheffield MEJ | Research square | 37034716 | Res Sq | 2023 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/37034716 |
Direct Thalamic Inputs to Hippocampal CA1 Transmit a Signal That Suppresses Ongoing Contextual Fear Memory Retrieval. | Ratigan HC, Krishnan S, Smith S, Sheffield MEJ | bioRxiv : the preprint server for biology | 37034812 | bioRxiv | 2023 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/37034812 |
BTSP, not STDP, Drives Shifts in Hippocampal Representations During Familiarization. | Madar AD, Dong C, Sheffield MEJ | bioRxiv : the preprint server for biology | 37904999 | bioRxiv | 2023 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/37904999 |
A preprocessing toolbox for 2-photon subcellular calcium imaging. | Jiang A, Zhao C, Sheffield M | bioRxiv : the preprint server for biology | 39605689 | bioRxiv | 2024 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/39605689 |
Synaptic plasticity rules driving representational shifting in the hippocampus. | Madar AD, Jiang A, Dong C, Sheffield MEJ | Nature neuroscience | 40113934 | Nat Neurosci | 2025 Apr | https://www.ncbi.nlm.nih.gov/pubmed/40113934 |
An Activity-Based Nanosensor for Traumatic Brain Injury. | Kudryashev JA, Waggoner LE, Leng HT, Mininni NH, Kwon EJ | ACS sensors | 32100994 | ACS Sens | 2020 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/32100994 |
Pharmacokinetic Analysis of Peptide-Modified Nanoparticles with Engineered Physicochemical Properties in a Mouse Model of Traumatic Brain Injury. | Waggoner LE, Madias MI, Hurtado AA, Kwon EJ | The AAPS journal | 34401968 | AAPS J | 2021 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/34401968 |
Targeting the Extracellular Matrix in Traumatic Brain Injury Increases Signal Generation from an Activity-Based Nanosensor. | Kandell RM, Kudryashev JA, Kwon EJ | ACS nano | 34870408 | ACS Nano | 2021 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/34870408 |
Porous Silicon Nanoparticles Targeted to the Extracellular Matrix for Therapeutic Protein Delivery in Traumatic Brain Injury. | Waggoner LE, Kang J, Zuidema JM, Vijayakumar S, Hurtado AA, Sailor MJ, Kwon EJ | Bioconjugate chemistry | 36017941 | Bioconjug Chem | 2022 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/36017941 |
An Activity-Based Nanosensor for Minimally-Invasive Measurement of Protease Activity in Traumatic Brain Injury. | Kudryashev JA, Madias MI, Kandell RM, Lin QX, Kwon EJ | Advanced functional materials | 37873031 | Adv Funct Mater | 2023 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/37873031 |
Analysis of PEG-lipid anchor length on lipid nanoparticle pharmacokinetics and activity in a mouse model of traumatic brain injury. | Waggoner LE, Miyasaki KF, Kwon EJ | Biomaterials science | 36987922 | Biomater Sci | 2023 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/36987922 |
Infusible Extracellular Matrix Biomaterial Promotes Vascular Integrity and Modulates the Inflammatory Response in Acute Traumatic Brain Injury. | Diaz MD, Kandell RM, Wu JR, Chen A, Christman KL, Kwon EJ | Advanced healthcare materials | 37390094 | Adv Healthc Mater | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37390094 |
Mechanobiological Modulation of In Vitro Astrocyte Reactivity Using Variable Gel Stiffness. | C Benincasa J, Madias MI, Kandell RM, Delgado-Garcia LM, Engler AJ, Kwon EJ, Porcionatto MA | ACS biomaterials science & engineering | 38870483 | ACS Biomater Sci Eng | 2024 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/38870483 |
Spatial Measurement and Inhibition of Calpain Activity in Traumatic Brain Injury with an Activity-Based Nanotheranostic Platform. | Madias MI, Stessman LN, Warlof SJ, Kudryashev JA, Kwon EJ | ACS nano | 39236689 | ACS Nano | 2024 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/39236689 |
PEGylated Multimeric RNA Nanoparticles for siRNA Delivery in Traumatic Brain Injury. | Han S, Yoo W, Carton O, Joo J, Kwon EJ | Small (Weinheim an der Bergstrasse, Germany) | 39498752 | Small | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39498752 |
Nanomedicine for Acute Brain Injuries: Insight from Decades of Cancer Nanomedicine. | Kandell RM, Waggoner LE, Kwon EJ | Molecular pharmaceutics | 32584042 | Mol Pharm | 2021 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/32584042 |
Reprograming Clots for In Vivo Chemical Targeting in Traumatic Brain Injury. | Kandell RM, Wu JR, Kwon EJ | Advanced materials (Deerfield Beach, Fla.) | 38780012 | Adv Mater | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38780012 |
Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain. | Wu JR, Hernandez Y, Miyasaki KF, Kwon EJ | Advanced drug delivery reviews | 37054953 | Adv Drug Deliv Rev | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37054953 |
Poison exons in neurodevelopment and disease. | Carvill GL, Mefford HC | Current opinion in genetics & development | 32615329 | Curr Opin Genet Dev | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32615329 |
Ultrasound-mediated blood-brain barrier opening increases cell-free DNA in a time-dependent manner. | Zhang DY, Gould A, Happ HC, Youngblood MW, Dmello C, Kang SJ, Canney M, Stupp R, Carvill GL, Sonabend AM | Neuro-oncology advances | 34993480 | Neurooncol Adv | 2021 Jan-Dec | https://www.ncbi.nlm.nih.gov/pubmed/34993480 |
Accurate neuron segmentation method for one-photon calcium imaging videos combining convolutional neural networks and clustering. | Bao Y, Gong Y | Communications biology | 39122882 | Commun Biol | 2024 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/39122882 |
Rational engineering of ratiometric calcium sensors with bright green and red fluorescent proteins. | Zhang D, Redington E, Gong Y | Communications biology | 34326458 | Commun Biol | 2021 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/34326458 |
Identifying properties of pattern completion neurons in a computational model of the visual cortex. | Baker CM, Gong Y | PLoS computational biology | 37279242 | PLoS Comput Biol | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37279242 |
A kinetic-optimized CoChR variant with enhanced high-frequency spiking fidelity. | Bi X, Beck C, Gong Y | Biophysical journal | 36151721 | Biophys J | 2022 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/36151721 |
Enhanced genetically encoded voltage indicators advance their applications in neuroscience. | Beck C, Zhang D, Gong Y | Current opinion in biomedical engineering | 32864526 | Curr Opin Biomed Eng | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32864526 |
A high-speed, bright, red fluorescent voltage sensor to detect neural activity. | Beck C, Gong Y | Scientific reports | 31685893 | Sci Rep | 2019 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/31685893 |
Engineering rhodopsins' activation spectra using a FRET-based approach. | Beck C, Gong Y | Biophysical journal | 35331688 | Biophys J | 2022 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/35331688 |
Genetically Encoded Fluorescent Indicators for Imaging Brain Chemistry. | Bi X, Beck C, Gong Y | Biosensors | 33920418 | Biosensors (Basel) | 2021 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/33920418 |
A Semi-supervised Pipeline for Accurate Neuron Segmentation with Fewer Ground Truth Labels. | Baker CM, Gong Y | eNeuro | 38242690 | eNeuro | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38242690 |
Decontaminate Traces From Fluorescence Calcium Imaging Videos Using Targeted Non-negative Matrix Factorization. | Bao Y, Redington E, Agarwal A, Gong Y | Frontiers in neuroscience | 35126042 | Front Neurosci | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/35126042 |
Segmentation of Neurons from Fluorescence Calcium Recordings Beyond Real-time. | Bao Y, Soltanian-Zadeh S, Farsiu S, Gong Y | Nature machine intelligence | 34485824 | Nat Mach Intell | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34485824 |
In-Cell NMR of Intact Mammalian Cells Preserved with the Cryoprotectants DMSO and Glycerol Have Similar DNP Performance. | Xiao Y, Ghosh R, Frederick KK | Frontiers in molecular biosciences | 35145995 | Front Mol Biosci | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/35145995 |
DNP-Assisted NMR Investigation of Proteins at Endogenous Levels in Cellular Milieu. | Costello WN, Xiao Y, Frederick KK | Methods in enzymology | 30638534 | Methods Enzymol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30638534 |
Spatially resolved DNP-assisted NMR illuminates the conformational ensemble of α-synuclein in intact viable cells. | Kragelj J, Ghosh R, Xiao Y, Dumarieh R, Lagasca D, Krishna S, Frederick KK | bioRxiv : the preprint server for biology | 37961511 | bioRxiv | 2025 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/37961511 |
In-Cell Sensitivity-Enhanced NMR of Intact Viable Mammalian Cells. | Ghosh R, Xiao Y, Kragelj J, Frederick KK | Journal of the American Chemical Society | 34724614 | J Am Chem Soc | 2021 Nov 10 | https://www.ncbi.nlm.nih.gov/pubmed/34724614 |
Michler's hydrol blue elucidates structural differences in prion strains. | Xiao Y, Rocha S, Kitts CC, Reymer A, Beke-Somfai T, Frederick KK, Nordén B | Proceedings of the National Academy of Sciences of the United States of America | 33168711 | Proc Natl Acad Sci U S A | 2020 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/33168711 |
Stability of the nitroxide biradical AMUPol in intact and lysed mammalian cells. | Ghosh R, Dumarieh R, Xiao Y, Frederick KK | Journal of magnetic resonance (San Diego, Calif. : 1997) | 35151975 | J Magn Reson | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35151975 |
Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability. | Ghosh R, Kragelj J, Xiao Y, Frederick KK | Journal of visualized experiments : JoVE | 32955491 | J Vis Exp | 2020 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/32955491 |
Conformational ensembles explain NMR spectra of frozen intrinsically disordered proteins. | Kragelj J, Dumarieh R, Xiao Y, Frederick KK | Protein science : a publication of the Protein Society | 36930141 | Protein Sci | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/36930141 |
In cell NMR reveals cells selectively amplify and structurally remodel amyloid fibrils. | Ansari S, Lagasca D, Dumarieh R, Xiao Y, Krishna S, Li Y, Frederick KK | bioRxiv : the preprint server for biology | 39314304 | bioRxiv | 2024 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/39314304 |
Structural context modulates the conformational ensemble of the intrinsically disordered amino terminus of α-synuclein. | Dumarieh R, Lagasca D, Krishna S, Kragelj J, Xiao Y, Frederick KK | bioRxiv : the preprint server for biology | 39553926 | bioRxiv | 2024 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/39553926 |
Stability of the polarization agent AsymPolPOK in intact and lysed mammalian cells. | Lagasca D, Ghosh R, Xiao Y, Frederick KK | bioRxiv : the preprint server for biology | 39605460 | bioRxiv | 2024 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/39605460 |
Context-Dependent Sensory Processing across Primary and Secondary Somatosensory Cortex. | Condylis C, Lowet E, Ni J, Bistrong K, Ouellette T, Josephs N, Chen JL | Neuron | 32164873 | Neuron | 2020 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/32164873 |
Transcriptional determinants of goal-directed learning and representational drift in the parahippocampal cortex. | McLachlan CA, Lee DG, Kwon O, Delgado KM, Manjrekar N, Yao Z, Zeng H, Tasic B, Chen JL | Cell reports | 39792551 | Cell Rep | 2025 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/39792551 |
CELLULAR RESOLUTION IMAGING OF NEURONAL ACTIVITY ACROSS SPACE AND TIME IN THE MAMMALIAN BRAIN. | Clough M, Chen JL | Current opinion in biomedical engineering | 32104747 | Curr Opin Biomed Eng | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32104747 |
Perirhinal cortex learns a predictive map of the task environment. | Lee DG, McLachlan CA, Nogueira R, Kwon O, Carey AE, House G, Lagani GD, LaMay D, Fusi S, Chen JL | Nature communications | 38956015 | Nat Commun | 2024 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/38956015 |
High-speed low-light in vivo two-photon voltage imaging of large neuronal populations. | Platisa J, Ye X, Ahrens AM, Liu C, Chen IA, Davison IG, Tian L, Pieribone VA, Chen JL | Nature methods | 36973547 | Nat Methods | 2023 Jul | https://www.ncbi.nlm.nih.gov/pubmed/36973547 |
PERIRHINAL CORTEX LEARNS A PREDICTIVE MAP (INTERNAL MODEL) OF THE TASK ENVIRONMENT. | Lee DG, McLachlan CA, Nogueira R, Kwon O, Carey AE, House G, Lagani GD, LaMay D, Fusi S, Chen JL | bioRxiv : the preprint server for biology | 36993645 | bioRxiv | 2023 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/36993645 |
Flexible simultaneous mesoscale two-photon imaging of neural activity at high speeds. | Clough M, Chen IA, Park SW, Ahrens AM, Stirman JN, Smith SL, Chen JL | Nature communications | 34789730 | Nat Commun | 2021 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/34789730 |
Dense functional and molecular readout of a circuit hub in sensory cortex. | Condylis C, Ghanbari A, Manjrekar N, Bistrong K, Yao S, Yao Z, Nguyen TN, Zeng H, Tasic B, Chen JL | Science (New York, N.Y.) | 34990233 | Science | 2022 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/34990233 |
SynapsEM: Computer-Assisted Synapse Morphometry. | Watanabe S, Davis MW, Kusick GF, Iwasa J, Jorgensen EM | Frontiers in synaptic neuroscience | 33390925 | Front Synaptic Neurosci | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33390925 |
Intersectin and Endophilin condensates prime synaptic vesicles for release site replenishment. | Ogunmowo T, Hoffmann C, Pepper R, Wang H, Gowrisankaran S, Ho A, Raychaudhuri S, Cooper BH, Milosevic I, Milovanovic D, Watanabe S | bioRxiv : the preprint server for biology | 37662300 | bioRxiv | 2023 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/37662300 |
Synaptic Vesicle Endocytosis in Different Model Systems. | Gan Q, Watanabe S | Frontiers in cellular neuroscience | 30002619 | Front Cell Neurosci | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30002619 |
Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses. | Li S, Raychaudhuri S, Lee SA, Brockmann MM, Wang J, Kusick G, Prater C, Syed S, Falahati H, Ramos R, Bartol TM, Hosy E, Watanabe S | Nature communications | 33514725 | Nat Commun | 2021 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/33514725 |
Membrane mechanics dictate axonal pearls-on-a-string morphology and function. | Griswold JM, Bonilla-Quintana M, Pepper R, Lee CT, Raychaudhuri S, Ma S, Gan Q, Syed S, Zhu C, Bell M, Suga M, Yamaguchi Y, Chéreau R, Nägerl UV, Knott G, Rangamani P, Watanabe S | Nature neuroscience | 39623218 | Nat Neurosci | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39623218 |
Synaptic vesicles transiently dock to refill release sites. | Kusick GF, Chin M, Raychaudhuri S, Lippmann K, Adula KP, Hujber EJ, Vu T, Davis MW, Jorgensen EM, Watanabe S | Nature neuroscience | 32989294 | Nat Neurosci | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32989294 |
Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons. | Vevea JD, Kusick GF, Courtney KC, Chen E, Watanabe S, Chapman ER | eLife | 34543184 | Elife | 2021 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/34543184 |
ActuAtor, a Listeria-inspired molecular tool for physical manipulation of intracellular organizations through de novo actin polymerization. | Nakamura H, Rho E, Lee CT, Itoh K, Deng D, Watanabe S, Razavi S, Matsubayashi HT, Zhu C, Jung E, Rangamani P, Watanabe S, Inoue T | Cell reports | 37734382 | Cell Rep | 2023 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/37734382 |
Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis. | Ogunmowo TH, Jing H, Raychaudhuri S, Kusick GF, Imoto Y, Li S, Itoh K, Ma Y, Jafri H, Dalva MB, Chapman ER, Ha T, Watanabe S, Liu J | Nature communications | 37210439 | Nat Commun | 2023 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/37210439 |
Membrane mechanics dictate axonal morphology and function. | Griswold JM, Bonilla-Quintana M, Pepper R, Lee CT, Raychaudhuri S, Ma S, Gan Q, Syed S, Zhu C, Bell M, Suga M, Yamaguchi Y, Chéreau R, Nägerl UV, Knott G, Rangamani P, Watanabe S | bioRxiv : the preprint server for biology | 37503105 | bioRxiv | 2023 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/37503105 |
Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis. | Imoto Y, Xue J, Luo L, Raychaudhuri S, Itoh K, Ma Y, Craft GE, Kwan AH, Mackay JP, Ha T, Watanabe S, Robinson PJ | bioRxiv : the preprint server for biology | 37790502 | bioRxiv | 2023 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/37790502 |
Beyond Clathrin: Decoding the Mechanism of Ultrafast Endocytosis. | Imoto Y, Watanabe S | Physiology (Bethesda, Md.) | 40062769 | Physiology (Bethesda) | 2025 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/40062769 |
The Synaptic Vesicle Cycle Revisited: New Insights into the Modes and Mechanisms. | Chanaday NL, Cousin MA, Milosevic I, Watanabe S, Morgan JR | The Journal of neuroscience : the official journal of the Society for Neuroscience | 31619489 | J Neurosci | 2019 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/31619489 |
Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release. | Wu Z, Kusick GF, Berns MMM, Raychaudhuri S, Itoh K, Walter AM, Chapman ER, Watanabe S | eLife | 38536730 | Elife | 2024 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/38536730 |
Transient docking of synaptic vesicles: Implications and mechanisms. | Kusick GF, Ogunmowo TH, Watanabe S | Current opinion in neurobiology | 35398664 | Curr Opin Neurobiol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35398664 |
Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A/acyltransferases. | Watanabe S, Nihongaki Y, Itoh K, Uyama T, Toda S, Watanabe S, Inoue T | Nature communications | 35906209 | Nat Commun | 2022 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/35906209 |
Dynamin is primed at endocytic sites for ultrafast endocytosis. | Imoto Y, Raychaudhuri S, Ma Y, Fenske P, Sandoval E, Itoh K, Blumrich EM, Matsubayashi HT, Mamer L, Zarebidaki F, Söhl-Kielczynski B, Trimbuch T, Nayak S, Iwasa JH, Liu J, Wu B, Ha T, Inoue T, Jorgensen EM, Cousin MA, Rosenmund C, Watanabe S | Neuron | 35809574 | Neuron | 2022 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/35809574 |
Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles. | Vettkötter D, Schneider M, Goulden BD, Dill H, Liewald J, Zeiler S, Guldan J, Ateş YA, Watanabe S, Gottschalk A | Nature communications | 36535932 | Nat Commun | 2022 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/36535932 |
Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis. | Imoto Y, Xue J, Luo L, Raychaudhuri S, Itoh K, Ma Y, Craft GE, Kwan AH, Ogunmowo TH, Ho A, Mackay JP, Ha T, Watanabe S, Robinson PJ | The EMBO journal | 38907032 | EMBO J | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38907032 |
Ultrastructural membrane dynamics of mouse and human cortical synapses. | Eddings CR, Fan M, Imoto Y, Itoh K, McDonald X, Eilers J, Anderson WS, Worley PF, Lippmann K, Nauen DW, Watanabe S | bioRxiv : the preprint server for biology | 39763840 | bioRxiv | 2024 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/39763840 |
Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons. | Moakley D, Koh J, Pereira JD, DuBreuil DM, Devlin AC, Berezovski E, Zhu K, Wainger BJ | Scientific reports | 31346219 | Sci Rep | 2019 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/31346219 |
Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial. | Weiss MD, Macklin EA, McIlduff CE, Vucic S, Wainger BJ, Kiernan MC, Goutman SA, Goyal NA, Rutkove SB, Ladha SS, Chen IA, Harms MB, Brannagan TH, Lacomis D, Zivkovic S, Ma M, Wang LH, Simmons Z, Rivner MH, Shefner JM, Cudkowicz ME, Atassi N, Mexiletine-2 ALS Study Group | Muscle & nerve | 33340120 | Muscle Nerve | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33340120 |
Modeling cell-autonomous motor neuron phenotypes in ALS using iPSCs. | Hawrot J, Imhof S, Wainger BJ | Neurobiology of disease | 31759135 | Neurobiol Dis | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31759135 |
Heat But Not Mechanical Hypersensitivity Depends on Voltage-Gated Ca(V)2.2 Calcium Channel Activity in Peripheral Axon Terminals Innervating Skin. | DuBreuil DM, Lopez Soto EJ, Daste S, Meir R, Li D, Wainger B, Fleischmann A, Lipscombe D | The Journal of neuroscience : the official journal of the Society for Neuroscience | 34353899 | J Neurosci | 2021 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/34353899 |
Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions. | Pereira JD, DuBreuil DM, Devlin AC, Held A, Sapir Y, Berezovski E, Hawrot J, Dorfman K, Chander V, Wainger BJ | Nature communications | 34362895 | Nat Commun | 2021 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/34362895 |
A high-content platform for physiological profiling and unbiased classification of individual neurons. | DuBreuil DM, Chiang BM, Zhu K, Lai X, Flynn P, Sapir Y, Wainger BJ | Cell reports methods | 34318289 | Cell Rep Methods | 2021 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/34318289 |
Phenotypic screen identifies the natural product silymarin as a novel anti-inflammatory analgesic. | DuBreuil DM, Lai X, Zhu K, Chahyadinata G, Perner C, Chiang BM, Battenberg A, Sokol CL, Wainger BJ | Molecular pain | 36526437 | Mol Pain | 2023 Jan-Dec | https://www.ncbi.nlm.nih.gov/pubmed/36526437 |
Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial. | Wainger BJ, Macklin EA, Vucic S, McIlduff CE, Paganoni S, Maragakis NJ, Bedlack R, Goyal NA, Rutkove SB, Lange DJ, Rivner MH, Goutman SA, Ladha SS, Mauricio EA, Baloh RH, Simmons Z, Pothier L, Kassis SB, La T, Hall M, Evora A, Klements D, Hurtado A, Pereira JD, Koh J, Celnik PA, Chaudhry V, Gable K, Juel VC, Phielipp N, Marei A, Rosenquist P, Meehan S, Oskarsson B, Lewis RA, Kaur D, Kiskinis E, Woolf CJ, Eggan K, Weiss MD, Berry JD, David WS, Davila-Perez P, Camprodon JA, Pascual-Leone A, Kiernan MC, Shefner JM, Atassi N, Cudkowicz ME | JAMA neurology | 33226425 | JAMA Neurol | 2021 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/33226425 |
iPSC motor neurons, but not other derived cell types, capture gene expression changes in postmortem sporadic ALS motor neurons. | Held A, Adler M, Marques C, Reyes CJ, Kavuturu AS, Quadros ARAA, Ndayambaje IS, Lara E, Ward M, Lagier-Tourenne C, Wainger BJ | Cell reports | 37651231 | Cell Rep | 2023 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/37651231 |
Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia. | Marques C, Held A, Dorfman K, Sung J, Song C, Kavuturu AS, Aguilar C, Russo T, Oakley DH, Albers MW, Hyman BT, Petrucelli L, Lagier-Tourenne C, Wainger BJ | Acta neuropathologica | 38478117 | Acta Neuropathol | 2024 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/38478117 |
Task-specific modulation of corticospinal neuron activity during motor learning in mice. | Serradj N, Marino F, Moreno-López Y, Bernstein A, Agger S, Soliman M, Sloan A, Hollis E | Nature communications | 37169765 | Nat Commun | 2023 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/37169765 |
Nicotinic acetylcholine signaling is required for motor learning but not for rehabilitation from spinal cord injury. | Li Y, Hollis Ii ER | Neural regeneration research | 35900431 | Neural Regen Res | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35900431 |
A Kinematic Deviation Index (KDI) for Evaluation of Forelimb Function in Rodents. | Torres-Espin A, Bernstein A, Soliman M, Jara JS, Moreno-López Y, Hollis E | bioRxiv : the preprint server for biology | 39386493 | bioRxiv | 2024 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/39386493 |
Acute Extrinsic Activation of the RANKL Pathway Decreases Wound Healing and Functional Recovery After Spinal Cord Injury in Mice. | Vivinetto AL, Bernstein A, Soliman M, Cave JW, Hollis E | Glia | 39828951 | Glia | 2025 May | https://www.ncbi.nlm.nih.gov/pubmed/39828951 |
Functional Electrical Stimulation and the Modulation of the Axon Regeneration Program. | Jara JS, Agger S, Hollis ER 2nd | Frontiers in cell and developmental biology | 33015031 | Front Cell Dev Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33015031 |
Basal Forebrain Cholinergic Neurons Selectively Drive Coordinated Motor Learning in Mice. | Li Y, Hollis E | The Journal of neuroscience : the official journal of the Society for Neuroscience | 34750228 | J Neurosci | 2021 Dec 8 | https://www.ncbi.nlm.nih.gov/pubmed/34750228 |
Cortical Reorganization of Sensorimotor Systems and the Role of Intracortical Circuits After Spinal Cord Injury. | Mohammed H, Hollis ER 2nd | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics | 29882081 | Neurotherapeutics | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29882081 |
Corticospinal Modulation of Precision Movements. | Marino F, Moreno-López Y, Hollis E | Neuroscience insights | 38680210 | Neurosci Insights | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38680210 |
Targeted Enhancer Activation by a Subunit of the Integrator Complex. | Barbieri E, Trizzino M, Welsh SA, Owens TA, Calabretta B, Carroll M, Sarma K, Gardini A | Molecular cell | 30008316 | Mol Cell | 2018 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/30008316 |
TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures. | Shukla V, Samaniego-Castruita D, Dong Z, González-Avalos E, Yan Q, Sarma K, Rao A | Nature immunology | 34937926 | Nat Immunol | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34937926 |
Targeted Nuclease Approaches for Mapping Native R-Loops. | Wulfridge P, Yan Q, Sarma K | Methods in molecular biology (Clifton, N.J.) | 35704205 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35704205 |
Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function. | Ren W, Medeiros N, Warneford-Thomson R, Wulfridge P, Yan Q, Bian J, Sidoli S, Garcia BA, Skordalakes E, Joyce E, Bonasio R, Sarma K | Nature communications | 32376827 | Nat Commun | 2020 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/32376827 |
A nuclease- and bisulfite-based strategy captures strand-specific R-loops genome-wide. | Wulfridge P, Sarma K | eLife | 33620319 | Elife | 2021 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/33620319 |
Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach. | Yan Q, Shields EJ, Bonasio R, Sarma K | Cell reports | 31665646 | Cell Rep | 2019 Oct 29 | https://www.ncbi.nlm.nih.gov/pubmed/31665646 |
MapR: A Method for Identifying Native R-Loops Genome Wide. | Yan Q, Sarma K | Current protocols in molecular biology | 31943854 | Curr Protoc Mol Biol | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31943854 |
ATRX histone binding and helicase activities have distinct roles in neuronal differentiation. | Bieluszewska A, Wulfridge P, Doherty J, Ren W, Sarma K | Nucleic acids research | 35998910 | Nucleic Acids Res | 2022 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/35998910 |
G-quadruplexes associated with R-loops promote CTCF binding. | Wulfridge P, Yan Q, Rell N, Doherty J, Jacobson S, Offley S, Deliard S, Feng K, Phillips-Cremins JE, Gardini A, Sarma K | Molecular cell | 37552993 | Mol Cell | 2023 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/37552993 |
Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. | Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang CA, Wu S, Zhou W, Guo D, Karakashev S, Hu CA, Sarma K, Kossenkov AV, Zhang R | Nature communications | 34493732 | Nat Commun | 2021 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/34493732 |
Proximity labeling identifies a repertoire of site-specific R-loop modulators. | Yan Q, Wulfridge P, Doherty J, Fernandez-Luna JL, Real PJ, Tang HY, Sarma K | Nature communications | 35013239 | Nat Commun | 2022 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/35013239 |
SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia. | Han C, Khodadadi-Jamayran A, Lorch AH, Jin Q, Serafin V, Zhu P, Politanska Y, Sun L, Gutierrez-Diaz BT, Pryzhkova MV, Abdala-Valencia H, Bartom ET, Buldini B, Basso G, Velu SE, Sarma K, Mattamana BB, Cho BK, Obeng RC, Goo YA, Jordan PW, Tsirigos A, Zhou Y, Ntziachristos P | Science advances | 35061527 | Sci Adv | 2022 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/35061527 |
The Cerebellar Nuclei and Dexterous Limb Movements. | Thanawalla AR, Chen AI, Azim E | Neuroscience | 32652173 | Neuroscience | 2020 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/32652173 |
Anipose: A toolkit for robust markerless 3D pose estimation. | Karashchuk P, Rupp KL, Dickinson ES, Walling-Bell S, Sanders E, Azim E, Brunton BW, Tuthill JC | Cell reports | 34592148 | Cell Rep | 2021 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/34592148 |
Reverse-translational identification of a cerebellar satiation network. | Low AYT, Goldstein N, Gaunt JR, Huang KP, Zainolabidin N, Yip AKK, Carty JRE, Choi JY, Miller AM, Ho HST, Lenherr C, Baltar N, Azim E, Sessions OM, Ch'ng TH, Bruce AS, Martin LE, Halko MA, Brady RO Jr, Holsen LM, Alhadeff AL, Chen AI, Betley JN | Nature | 34789878 | Nature | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34789878 |
Selective Targeting of a Defined Subpopulation of Corticospinal Neurons using a Novel Klhl14-Cre Mouse Line Enables Molecular and Anatomical Investigations through Development into Maturity. | Lustig J, Lammers A, Kaiser J, Patel P, Raghu A, Conner JM, Nguyen P, Azim E, Sahni V | bioRxiv : the preprint server for biology | 39713479 | bioRxiv | 2024 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/39713479 |
Proprioception. | Tuthill JC, Azim E | Current biology : CB | 29510103 | Curr Biol | 2018 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/29510103 |
Gain control in the sensorimotor system. | Azim E, Seki K | Current opinion in physiology | 31403088 | Curr Opin Physiol | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31403088 |
Modulation of tactile feedback for the execution of dexterous movement. | Conner JM, Bohannon A, Igarashi M, Taniguchi J, Baltar N, Azim E | Science (New York, N.Y.) | 34648327 | Science | 2021 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/34648327 |
Large-scale capture of hidden fluorescent labels for training generalizable markerless motion capture models. | Butler DJ, Keim AP, Ray S, Azim E | Nature communications | 37752123 | Nat Commun | 2023 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/37752123 |
The Sensorimotor Basis of Whisker-Guided Anteroposterior Object Localization in Head-Fixed Mice. | Cheung J, Maire P, Kim J, Sy J, Hires SA | Current biology : CB | 31474537 | Curr Biol | 2019 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/31474537 |
Behavioral and Neural Bases of Tactile Shape Discrimination Learning in Head-Fixed Mice. | Kim J, Erskine A, Cheung JA, Hires SA | Neuron | 33002411 | Neuron | 2020 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/33002411 |
Dynamic cues for whisker-based object localization: An analytical solution to vibration during active whisker touch. | Vaxenburg R, Wyche I, Svoboda K, Efros AL, Hires SA | PLoS computational biology | 29584719 | PLoS Comput Biol | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29584719 |
GABA co-released from striatal dopamine axons dampens phasic dopamine release through autoregulatory GABA(A) receptors. | Patel JC, Sherpa AD, Melani R, Witkovsky P, Wiseman MR, O'Neill B, Aoki C, Tritsch NX, Rice ME | Cell reports | 38431842 | Cell Rep | 2024 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/38431842 |
Intrinsic dopamine and acetylcholine dynamics in the striatum of mice. | Krok AC, Maltese M, Mistry P, Miao X, Li Y, Tritsch NX | Nature | 37558873 | Nature | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37558873 |
Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum. | Maltese M, March JR, Bashaw AG, Tritsch NX | eLife | 33983121 | Elife | 2021 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/33983121 |
Inhibitory co-transmission from midbrain dopamine neurons relies on presynaptic GABA uptake. | Melani R, Tritsch NX | Cell reports | 35443174 | Cell Rep | 2022 Apr 19 | https://www.ncbi.nlm.nih.gov/pubmed/35443174 |
Posterior amygdala regulates sexual and aggressive behaviors in male mice. | Yamaguchi T, Wei D, Song SC, Lim B, Tritsch NX, Lin D | Nature neuroscience | 32719562 | Nat Neurosci | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32719562 |
Unraveling the dynamics of dopamine release and its actions on target cells. | Sippy T, Tritsch NX | Trends in neurosciences | 36635111 | Trends Neurosci | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36635111 |
Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice. | Longo F, Aryal S, Anastasiades PG, Maltese M, Baimel C, Albanese F, Tabor J, Zhu JD, Oliveira MM, Gastaldo D, Bagni C, Santini E, Tritsch NX, Carter AG, Klann E | Cell reports | 37505982 | Cell Rep | 2023 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/37505982 |
Acetylcholine waves and dopamine release in the striatum. | Matityahu L, Gilin N, Sarpong GA, Atamna Y, Tiroshi L, Tritsch NX, Wickens JR, Goldberg JA | Nature communications | 37891198 | Nat Commun | 2023 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/37891198 |
A Hypothalamic Midbrain Pathway Essential for Driving Maternal Behaviors. | Fang YY, Yamaguchi T, Song SC, Tritsch NX, Lin D | Neuron | 29621487 | Neuron | 2018 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/29621487 |
G protein-coupled receptors cooperate to silence dopamine neurons. | Liu H, Tritsch NX | The Journal of physiology | 36214545 | J Physiol | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/36214545 |
Silicon Nanowires for Intracellular Optical Interrogation with Subcellular Resolution. | Rotenberg MY, Elbaz B, Nair V, Schaumann EN, Yamamoto N, Sarma N, Matino L, Santoro F, Tian B | Nano letters | 31904975 | Nano Lett | 2020 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/31904975 |
Inorganic semiconductor biointerfaces. | Jiang Y, Tian B | Nature reviews. Materials | 31656635 | Nat Rev Mater | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31656635 |
Biomimetic Approaches Toward Smart Bio-hybrid Systems. | Luo Z, Weiss DE, Liu Q, Tian B | Nano research | 30906509 | Nano Res | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30906509 |
Rational design of silicon structures for optically controlled multiscale biointerfaces. | Jiang Y, Li X, Liu B, Yi J, Fang Y, Shi F, Gao X, Sudzilovsky E, Parameswaran R, Koehler K, Nair V, Yue J, Guo K, Fang Y, Tsai HM, Freyermuth G, Wong RCS, Kao CM, Chen CT, Nicholls AW, Wu X, Shepherd GMG, Tian B | Nature biomedical engineering | 30906646 | Nat Biomed Eng | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30906646 |
Alloy-assisted deposition of three-dimensional arrays of atomic gold catalyst for crystal growth studies. | Fang Y, Jiang Y, Cherukara MJ, Shi F, Koehler K, Freyermuth G, Isheim D, Narayanan B, Nicholls AW, Seidman DN, Sankaranarayanan SKRS, Tian B | Nature communications | 29222439 | Nat Commun | 2017 Dec 8 | https://www.ncbi.nlm.nih.gov/pubmed/29222439 |
Nongenetic Optical Methods for Measuring and Modulating Neuronal Response. | Zimmerman JF, Tian B | ACS nano | 29727159 | ACS Nano | 2018 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/29727159 |
Learning from Solar Energy Conversion: Biointerfaces for Artificial Photosynthesis and Biological Modulation. | Lee YV, Tian B | Nano letters | 30888185 | Nano Lett | 2019 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/30888185 |
Talking to cells: semiconductor nanomaterials at the cellular interface. | Rotenberg MY, Tian B | Advanced biosystems | 30906852 | Adv Biosyst | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30906852 |
Dissecting Biological and Synthetic Soft-Hard Interfaces for Tissue-Like Systems. | Fang Y, Yang X, Lin Y, Shi J, Prominski A, Clayton C, Ostroff E, Tian B | Chemical reviews | 34677943 | Chem Rev | 2022 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/34677943 |
Soft-Hard Composites for Bioelectric Interfaces. | Lin Y, Fang Y, Yue J, Tian B | Trends in chemistry | 34296076 | Trends Chem | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34296076 |
Laser writing of nitrogen-doped silicon carbide for biological modulation. | Nair V, Yi J, Isheim D, Rotenberg M, Meng L, Shi F, Chen X, Gao X, Prominski A, Jiang Y, Yue J, Gallagher CT, Seidman DN, Tian B | Science advances | 32937377 | Sci Adv | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32937377 |
Recent advances in bioelectronics chemistry. | Fang Y , Meng L , Prominski A , Schaumann EN , Seebald M , Tian B | Chemical Society reviews | 32672777 | Chem Soc Rev | 2020 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/32672777 |
Photoelectrochemical modulation of neuronal activity with free-standing coaxial silicon nanowires. | Parameswaran R, Carvalho-de-Souza JL, Jiang Y, Burke MJ, Zimmerman JF, Koehler K, Phillips AW, Yi J, Adams EJ, Bezanilla F, Tian B | Nature nanotechnology | 29459654 | Nat Nanotechnol | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29459654 |
Nano-enabled cellular engineering for bioelectric studies. | Shi J, Clayton C, Tian B | Nano research | 34295455 | Nano Res | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/34295455 |
Nongenetic optical neuromodulation with silicon-based materials. | Jiang Y, Parameswaran R, Li X, Carvalho-de-Souza JL, Gao X, Meng L, Bezanilla F, Shepherd GMG, Tian B | Nature protocols | 30980031 | Nat Protoc | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30980031 |
Nanowired Bioelectric Interfaces. | Tian B, Lieber CM | Chemical reviews | 30995019 | Chem Rev | 2019 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/30995019 |
Optical stimulation of cardiac cells with a polymer-supported silicon nanowire matrix. | Parameswaran R, Koehler K, Rotenberg MY, Burke MJ, Kim J, Jeong KY, Hissa B, Paul MD, Moreno K, Sarma N, Hayes T, Sudzilovsky E, Park HG, Tian B | Proceedings of the National Academy of Sciences of the United States of America | 30538202 | Proc Natl Acad Sci U S A | 2019 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/30538202 |
Living myofibroblast-silicon composites for probing electrical coupling in cardiac systems. | Rotenberg MY, Yamamoto N, Schaumann EN, Matino L, Santoro F, Tian B | Proceedings of the National Academy of Sciences of the United States of America | 31624124 | Proc Natl Acad Sci U S A | 2019 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/31624124 |
An atlas of nano-enabled neural interfaces. | Acarón Ledesma H, Li X, Carvalho-de-Souza JL, Wei W, Bezanilla F, Tian B | Nature nanotechnology | 31270446 | Nat Nanotechnol | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31270446 |
Texturing Silicon Nanowires for Highly Localized Optical Modulation of Cellular Dynamics. | Fang Y, Jiang Y, Acaron Ledesma H, Yi J, Gao X, Weiss DE, Shi F, Tian B | Nano letters | 29894630 | Nano Lett | 2018 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/29894630 |
Micelle-enabled self-assembly of porous and monolithic carbon membranes for bioelectronic interfaces. | Fang Y, Prominski A, Rotenberg MY, Meng L, Acarón Ledesma H, Lv Y, Yue J, Schaumann E, Jeong J, Yamamoto N, Jiang Y, Elbaz B, Wei W, Tian B | Nature nanotechnology | 33288948 | Nat Nanotechnol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33288948 |
Tracking Longitudinal Rotation of Silicon Nanowires for Biointerfaces. | Lee YV, Wu D, Fang Y, Peng Y, Tian B | Nano letters | 32208712 | Nano Lett | 2020 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/32208712 |
Biological Interfaces, Modulation, and Sensing with Inorganic Nano-Bioelectronic Materials. | Schaumann EN, Tian B | Small methods | 34295965 | Small Methods | 2020 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/34295965 |
Electrical signals in the ER are cell type and stimulus specific with extreme spatial compartmentalization in neurons. | Campbell EP, Abushawish AA, Valdez LA, Bell MK, Haryono M, Rangamani P, Bloodgood BL | Cell reports | 36640310 | Cell Rep | 2023 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/36640310 |
Experimental and statistical reevaluation provides no evidence for Drosophila courtship song rhythms. | Stern DL, Clemens J, Coen P, Calhoun AJ, Hogenesch JB, Arthur BJ, Murthy M | Proceedings of the National Academy of Sciences of the United States of America | 28851830 | Proc Natl Acad Sci U S A | 2017 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/28851830 |
Singing on the fly: sensorimotor integration and acoustic communication in Drosophila. | Coen P, Murthy M | Current opinion in neurobiology | 26874218 | Curr Opin Neurobiol | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26874218 |
Discovery of a New Song Mode in Drosophila Reveals Hidden Structure in the Sensory and Neural Drivers of Behavior. | Clemens J, Coen P, Roemschied FA, Pereira TD, Mazumder D, Aldarondo DE, Pacheco DA, Murthy M | Current biology : CB | 30057309 | Curr Biol | 2018 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/30057309 |
Cell-Type-Specific Transcriptome Analysis in the Drosophila Mushroom Body Reveals Memory-Related Changes in Gene Expression. | Crocker A, Guan XJ, Murphy CT, Murthy M | Cell reports | 27160913 | Cell Rep | 2016 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/27160913 |
Auditory activity is diverse and widespread throughout the central brain of Drosophila. | Pacheco DA, Thiberge SY, Pnevmatikakis E, Murthy M | Nature neuroscience | 33230320 | Nat Neurosci | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33230320 |
Connecting Neural Codes with Behavior in the Auditory System of Drosophila. | Clemens J, Girardin CC, Coen P, Guan XJ, Dickson BJ, Murthy M | Neuron | 26365767 | Neuron | 2015 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/26365767 |
Fast intensity adaptation enhances the encoding of sound in Drosophila. | Clemens J, Ozeri-Engelhard N, Murthy M | Nature communications | 29317624 | Nat Commun | 2018 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/29317624 |
Neural network organization for courtship-song feature detection in Drosophila. | Baker CA, McKellar C, Pang R, Nern A, Dorkenwald S, Pacheco DA, Eckstein N, Funke J, Dickson BJ, Murthy M | Current biology : CB | 35793679 | Curr Biol | 2022 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/35793679 |
Acoustic Pattern Recognition and Courtship Songs: Insights from Insects. | Baker CA, Clemens J, Murthy M | Annual review of neuroscience | 30786225 | Annu Rev Neurosci | 2019 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/30786225 |
Quantifying behavior to solve sensorimotor transformations: advances from worms and flies. | Calhoun AJ, Murthy M | Current opinion in neurobiology | 28850885 | Curr Opin Neurobiol | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28850885 |
Shared Song Detector Neurons in Drosophila Male and Female Brains Drive Sex-Specific Behaviors. | Deutsch D, Clemens J, Thiberge SY, Guan G, Murthy M | Current biology : CB | 31564492 | Curr Biol | 2019 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/31564492 |
Sensorimotor Transformations Underlying Variability in Song Intensity during Drosophila Courtship. | Coen P, Xie M, Clemens J, Murthy M | Neuron | 26844835 | Neuron | 2016 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/26844835 |
Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types. | Ravindra Kumar S, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V | Nature methods | 32313222 | Nat Methods | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32313222 |
Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems. | Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sánchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V | Nature neuroscience | 28671695 | Nat Neurosci | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28671695 |
Extracting structural and functional features of widely distributed biological circuits with single cell resolution via tissue clearing and delivery vectors. | Treweek JB, Gradinaru V | Current opinion in biotechnology | 27393829 | Curr Opin Biotechnol | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27393829 |
Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors. | Patriarchi T, Cho JR, Merten K, Howe MW, Marley A, Xiong WH, Folk RW, Broussard GJ, Liang R, Jang MJ, Zhong H, Dombeck D, von Zastrow M, Nimmerjahn A, Gradinaru V, Williams JT, Tian L | Science (New York, N.Y.) | 29853555 | Science | 2018 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/29853555 |
Single-cell phenotyping within transparent intact tissue through whole-body clearing. | Yang B, Treweek JB, Kulkarni RP, Deverman BE, Chen CK, Lubeck E, Shah S, Cai L, Gradinaru V | Cell | 25088144 | Cell | 2014 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/25088144 |
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping. | Treweek JB, Chan KY, Flytzanis NC, Yang B, Deverman BE, Greenbaum A, Lignell A, Xiao C, Cai L, Ladinsky MS, Bjorkman PJ, Fowlkes CC, Gradinaru V | Nature protocols | 26492141 | Nat Protoc | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26492141 |
AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset. | Goertsen D, Flytzanis NC, Goeden N, Chuapoco MR, Cummins A, Chen Y, Fan Y, Zhang Q, Sharma J, Duan Y, Wang L, Feng G, Chen Y, Ip NY, Pickel J, Gradinaru V | Nature neuroscience | 34887588 | Nat Neurosci | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34887588 |
Light-guided sectioning for precise in situ localization and tissue interface analysis for brain-implanted optical fibers and GRIN lenses. | Kahan A, Greenbaum A, Jang MJ, Robinson JE, Cho JR, Chen X, Kassraian P, Wagenaar DA, Gradinaru V | Cell reports | 34592157 | Cell Rep | 2021 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/34592157 |
Dopaminergic dysfunction in neurodevelopmental disorders: recent advances and synergistic technologies to aid basic research. | Robinson JE, Gradinaru V | Current opinion in neurobiology | 28850815 | Curr Opin Neurobiol | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/28850815 |
Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics. | Bedbrook CN, Yang KK, Robinson JE, Mackey ED, Gradinaru V, Arnold FH | Nature methods | 31611694 | Nat Methods | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31611694 |
Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo. | Bedbrook CN, Kato M, Ravindra Kumar S, Lakshmanan A, Nath RD, Sun F, Sternberg PW, Arnold FH, Gradinaru V | Chemistry & biology | 26211362 | Chem Biol | 2015 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/26211362 |
Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice. | Challis C, Hori A, Sampson TR, Yoo BB, Challis RC, Hamilton AM, Mazmanian SK, Volpicelli-Daley LA, Gradinaru V | Nature neuroscience | 32066981 | Nat Neurosci | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32066981 |
Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways. | Xiao C, Cho JR, Zhou C, Treweek JB, Chan K, McKinney SL, Yang B, Gradinaru V | Neuron | 27100197 | Neuron | 2016 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/27100197 |
The Jellyfish Cassiopea Exhibits a Sleep-like State. | Nath RD, Bedbrook CN, Abrams MJ, Basinger T, Bois JS, Prober DA, Sternberg PW, Gradinaru V, Goentoro L | Current biology : CB | 28943083 | Curr Biol | 2017 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/28943083 |
Use of high-content imaging to quantify transduction of AAV-PHP viruses in the brain following systemic delivery. | Smith EJ, Farshim PP, Flomen R, Jones ST, McAteer SJ, Deverman BE, Gradinaru V, Bates GP | Brain communications | 34131644 | Brain Commun | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34131644 |
Directed evolution of a far-red fluorescent rhodopsin. | McIsaac RS, Engqvist MK, Wannier T, Rosenthal AZ, Herwig L, Flytzanis NC, Imasheva ES, Lanyi JK, Balashov SP, Gradinaru V, Arnold FH | Proceedings of the National Academy of Sciences of the United States of America | 25157169 | Proc Natl Acad Sci U S A | 2014 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/25157169 |
Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons. | Flytzanis NC, Bedbrook CN, Chiu H, Engqvist MK, Xiao C, Chan KY, Sternberg PW, Arnold FH, Gradinaru V | Nature communications | 25222271 | Nat Commun | 2014 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/25222271 |
Viral Strategies for Targeting the Central and Peripheral Nervous Systems. | Bedbrook CN, Deverman BE, Gradinaru V | Annual review of neuroscience | 29709207 | Annu Rev Neurosci | 2018 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/29709207 |
Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology? | Greenbaum A, Jang MJ, Challis C, Gradinaru V | BMC biology | 28946882 | BMC Biol | 2017 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/28946882 |
Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies. | Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, Shivkumar K | Nature communications | 31028266 | Nat Commun | 2019 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/31028266 |
Hydrogel-Tissue Chemistry: Principles and Applications. | Gradinaru V, Treweek J, Overton K, Deisseroth K | Annual review of biophysics | 29792820 | Annu Rev Biophys | 2018 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/29792820 |
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. | Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, Wu WL, Yang B, Huber N, Pasca SP, Gradinaru V | Nature biotechnology | 26829320 | Nat Biotechnol | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26829320 |
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. | Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan E, Huang SF, Kumar SR, Arokiaraj CM, Plattner V, Campos LJ, Mich J, Monet D, Ngo V, Ding X, Omstead V, Weed N, Bishaw Y, Gore B, Lein ES, Akrami A, Miller C, Levi BP, Keller A, Ting JT, Fox AS, Eroglu C, Gradinaru V | bioRxiv : the preprint server for biology | 36711773 | bioRxiv | 2023 Jan 13 | https://www.ncbi.nlm.nih.gov/pubmed/36711773 |
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. | Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, Ngo V, Ding X, Omstead V, Weed N, Bishaw Y, Gore BB, Lein ES, Akrami A, Miller C, Levi BP, Keller A, Ting JT, Fox AS, Eroglu C, Gradinaru V | Nature communications | 37291094 | Nat Commun | 2023 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/37291094 |
Tools for Understanding Nanoscale Lipid Regulation of Ion Channels. | Robinson CV, Rohacs T, Hansen SB | Trends in biochemical sciences | 31060927 | Trends Biochem Sci | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31060927 |
A Soluble Fluorescent Binding Assay Reveals PIP(2) Antagonism of TREK-1 Channels. | Cabanos C, Wang M, Han X, Hansen SB | Cell reports | 28793254 | Cell Rep | 2017 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/28793254 |
A Molecular Target for an Alcohol Chain-Length Cutoff. | Chung HW, Petersen EN, Cabanos C, Murphy KR, Pavel MA, Hansen AS, Ja WW, Hansen SB | Journal of molecular biology | 30529033 | J Mol Biol | 2019 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/30529033 |
Lipid agonism: The PIP2 paradigm of ligand-gated ion channels. | Hansen SB | Biochimica et biophysica acta | 25633344 | Biochim Biophys Acta | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25633344 |
Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol. | Wang H, Kulas JA, Wang C, Holtzman DM, Ferris HA, Hansen SB | Proceedings of the National Academy of Sciences of the United States of America | 34385305 | Proc Natl Acad Sci U S A | 2021 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/34385305 |
Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling. | Petersen EN, Pavel MA, Hansen SS, Gudheti M, Wang H, Yuan Z, Murphy KR, Ja W, Ferris HA, Jorgensen E, Hansen SB | eLife | 38407149 | Elife | 2024 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/38407149 |
Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D. | Petersen EN, Chung HW, Nayebosadri A, Hansen SB | Nature communications | 27976674 | Nat Commun | 2016 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/27976674 |
Studies on the mechanism of general anesthesia. | Pavel MA, Petersen EN, Wang H, Lerner RA, Hansen SB | Proceedings of the National Academy of Sciences of the United States of America | 32467161 | Proc Natl Acad Sci U S A | 2020 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/32467161 |
Disruption of palmitate-mediated localization; a shared pathway of force and anesthetic activation of TREK-1 channels. | Petersen EN, Pavel MA, Wang H, Hansen SB | Biochimica et biophysica acta. Biomembranes | 31672538 | Biochim Biophys Acta Biomembr | 2020 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/31672538 |
Cholesterol Regulation of Membrane Proteins Revealed by Two-Color Super-Resolution Imaging. | Yuan Z, Hansen SB | Membranes | 36837753 | Membranes (Basel) | 2023 Feb 20 | https://www.ncbi.nlm.nih.gov/pubmed/36837753 |
Distinct Dopamine Receptor Pathways Underlie the Temporal Sensitivity of Associative Learning. | Handler A, Graham TGW, Cohn R, Morantte I, Siliciano AF, Zeng J, Li Y, Ruta V | Cell | 31230716 | Cell | 2019 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/31230716 |
Evolution of a central neural circuit underlies Drosophila mate preferences. | Seeholzer LF, Seppo M, Stern DL, Ruta V | Nature | 29995860 | Nature | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29995860 |
Multimodal Chemosensory Circuits Controlling Male Courtship in Drosophila. | Clowney EJ, Iguchi S, Bussell JJ, Scheer E, Ruta V | Neuron | 26279475 | Neuron | 2015 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/26279475 |
Coordinated and Compartmentalized Neuromodulation Shapes Sensory Processing in Drosophila. | Cohn R, Morantte I, Ruta V | Cell | 26687359 | Cell | 2015 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/26687359 |
Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways. | Zolin A, Cohn R, Pang R, Siliciano AF, Fairhall AL, Ruta V | Nature neuroscience | 34697455 | Nat Neurosci | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34697455 |
A Taste Circuit that Regulates Ingestion by Integrating Food and Hunger Signals. | Yapici N, Cohn R, Schusterreiter C, Ruta V, Vosshall LB | Cell | 27040496 | Cell | 2016 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/27040496 |
Cortical gamma band synchronization through somatostatin interneurons. | Veit J, Hakim R, Jadi MP, Sejnowski TJ, Adesnik H | Nature neuroscience | 28481348 | Nat Neurosci | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28481348 |
A direct translaminar inhibitory circuit tunes cortical output. | Pluta S, Naka A, Veit J, Telian G, Yao L, Hakim R, Taylor D, Adesnik H | Nature neuroscience | 26414615 | Nat Neurosci | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26414615 |
Three-dimensional scanless holographic optogenetics with temporal focusing (3D-SHOT). | Pégard NC, Mardinly AR, Oldenburg IA, Sridharan S, Waller L, Adesnik H | Nature communications | 29089483 | Nat Commun | 2017 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/29089483 |
Precise multimodal optical control of neural ensemble activity. | Mardinly AR, Oldenburg IA, Pégard NC, Sridharan S, Lyall EH, Chesnov K, Brohawn SG, Waller L, Adesnik H | Nature neuroscience | 29713079 | Nat Neurosci | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29713079 |
Cracking the Function of Layers in the Sensory Cortex. | Adesnik H, Naka A | Neuron | 30521778 | Neuron | 2018 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/30521778 |
Synthesis of a comprehensive population code for contextual features in the awake sensory cortex. | Lyall EH, Mossing DP, Pluta SR, Chu YW, Dudai A, Adesnik H | eLife | 34723796 | Elife | 2021 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/34723796 |
Superficial Layers Suppress the Deep Layers to Fine-tune Cortical Coding. | Pluta SR, Telian GI, Naka A, Adesnik H | The Journal of neuroscience : the official journal of the Society for Neuroscience | 30651326 | J Neurosci | 2019 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/30651326 |
Complementary networks of cortical somatostatin interneurons enforce layer specific control. | Naka A, Veit J, Shababo B, Chance RK, Risso D, Stafford D, Snyder B, Egladyous A, Chu D, Sridharan S, Mossing DP, Paninski L, Ngai J, Adesnik H | eLife | 30883329 | Elife | 2019 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/30883329 |
Inhibitory Circuits in Cortical Layer 5. | Naka A, Adesnik H | Frontiers in neural circuits | 27199675 | Front Neural Circuits | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27199675 |
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Light sensitization of DNA nanostructures via incorporation of photo-cleavable spacers. | Kohman RE, Han X | Chemical communications (Cambridge, England) | 25720373 | Chem Commun (Camb) | 2015 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/25720373 |
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Accurate nanoelectrode recording of human pluripotent stem cell-derived cardiomyocytes for assaying drugs and modeling disease. | Lin ZC, McGuire AF, Burridge PW, Matsa E, Lou HY, Wu JC, Cui B | Microsystems & nanoengineering | 31057850 | Microsyst Nanoeng | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/31057850 |
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Activity-dependent BDNF release via endocytic pathways is regulated by synaptotagmin-6 and complexin. | Wong YH, Lee CM, Xie W, Cui B, Poo MM | Proceedings of the National Academy of Sciences of the United States of America | 26216953 | Proc Natl Acad Sci U S A | 2015 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/26216953 |
The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress. | Ong Q, Guo S, Duan L, Zhang K, Collier EA, Cui B | PloS one | 27082641 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27082641 |
Optogenetic control of molecular motors and organelle distributions in cells. | Duan L, Che D, Zhang K, Ong Q, Guo S, Cui B | Chemistry & biology | 25963241 | Chem Biol | 2015 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/25963241 |
Dual-Functional Lipid Coating for the Nanopillar-Based Capture of Circulating Tumor Cells with High Purity and Efficiency. | Lou HY, Zhao W, Hanson L, Zeng C, Cui Y, Cui B | Langmuir : the ACS journal of surfaces and colloids | 28059522 | Langmuir | 2017 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/28059522 |
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Vertical nanopillars for highly localized fluorescence imaging. | Xie C, Hanson L, Cui Y, Cui B | Proceedings of the National Academy of Sciences of the United States of America | 21368157 | Proc Natl Acad Sci U S A | 2011 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/21368157 |
Control of cerebral ischemia with magnetic nanoparticles. | Jia JM, Chowdary PD, Gao X, Ci B, Li W, Mulgaonkar A, Plautz EJ, Hassan G, Kumar A, Stowe AM, Yang SH, Zhou W, Sun X, Cui B, Ge WP | Nature methods | 27941784 | Nat Methods | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/27941784 |
Revealing the Cell-Material Interface with Nanometer Resolution by Focused Ion Beam/Scanning Electron Microscopy. | Santoro F, Zhao W, Joubert LM, Duan L, Schnitker J, van de Burgt Y, Lou HY, Liu B, Salleo A, Cui L, Cui Y, Cui B | ACS nano | 28682058 | ACS Nano | 2017 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/28682058 |
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The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells. | Che DL, Duan L, Zhang K, Cui B | ACS synthetic biology | 25985220 | ACS Synth Biol | 2015 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/25985220 |
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Nanoscale manipulation of membrane curvature for probing endocytosis in live cells. | Zhao W, Hanson L, Lou HY, Akamatsu M, Chowdary PD, Santoro F, Marks JR, Grassart A, Drubin DG, Cui Y, Cui B | Nature nanotechnology | 28581510 | Nat Nanotechnol | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28581510 |
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Dynamic Clustering of Dyneins on Axonal Endosomes: Evidence from High-Speed Darkfield Imaging. | Chowdary PD, Kaplan L, Che DL, Cui B | Biophysical journal | 29933888 | Biophys J | 2018 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/29933888 |
Light-mediated kinetic control reveals the temporal effect of the Raf/MEK/ERK pathway in PC12 cell neurite outgrowth. | Zhang K, Duan L, Ong Q, Lin Z, Varman PM, Sung K, Cui B | PloS one | 24667437 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24667437 |
Lighting up FGFR signaling. | Zhang K, Cui B | Chemistry & biology | 25036775 | Chem Biol | 2014 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/25036775 |
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RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADR. | Matthews EA, Russ JB, Qian Y, Zhao S, Thompson P, Methani M, Vestal ML, Josh Huang Z, Southwell DG | bioRxiv : the preprint server for biology | 39677799 | bioRxiv | 2024 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/39677799 |
Circuit-Based Understanding of Fine Spatial Scale Clustering of Orientation Tuning in Mouse Visual Cortex. | Yu P, Yang Y, Gozel O, Oldenburg I, Dipoppa M, Rossi LF, Miller K, Adesnik H, Ji N, Doiron B | bioRxiv : the preprint server for biology | 39990306 | bioRxiv | 2025 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/39990306 |
Rapid, biochemical tagging of cellular activity history in vivo. | Zhang R, Anguiano M, Aarrestad IK, Lin S, Chandra J, Vadde SS, Olson DE, Kim CK | bioRxiv : the preprint server for biology | 38798353 | bioRxiv | 2024 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/38798353 |
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Neuromodulator and neuropeptide sensors and probes for precise circuit interrogation in vivo. | Muir J, Anguiano M, Kim CK | Science (New York, N.Y.) | 39325905 | Science | 2024 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/39325905 |
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A hippocampal circuit mechanism to balance memory reactivation during sleep. | Karaba LA, Robinson HL, Harvey RE, Chen W, Fernandez-Ruiz A, Oliva A | Science (New York, N.Y.) | 39146421 | Science | 2024 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/39146421 |
Associative and predictive hippocampal codes support memory-guided behaviors. | Liu C, Todorova R, Tang W, Oliva A, Fernandez-Ruiz A | Science (New York, N.Y.) | 37856604 | Science | 2023 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/37856604 |
Ventral hippocampal parvalbumin interneurons gate the acute anxiolytic action of the serotonergic psychedelic DOI. | Tiwari P, Davoudian PA, Kapri D, Vuruputuri RM, Karaba LA, Sharma M, Zanni G, Balakrishnan A, Chaudhari PR, Pradhan A, Suryavanshi S, Bath KG, Ansorge MS, Fernandez-Ruiz A, Kwan AC, Vaidya VA | Neuron | 39321791 | Neuron | 2024 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/39321791 |
Mild focal cooling selectively impacts computations in dendritic trees. | Matin MH, Xiao S, Jayant K | bioRxiv : the preprint server for biology | 39553978 | bioRxiv | 2024 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/39553978 |
A Translaminar Spacetime Code Supports Touch-Evoked Traveling Waves. | Gonzales DL, Khan HF, Keri HVS, Yadav S, Steward C, Muller LE, Pluta SR, Jayant K | bioRxiv : the preprint server for biology | 38766232 | bioRxiv | 2024 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/38766232 |
Touch-evoked traveling waves establish a translaminar spacetime code. | Gonzales DL, Khan HF, Keri HVS, Yadav S, Steward C, Muller LE, Pluta SR, Jayant K | Science advances | 39889002 | Sci Adv | 2025 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/39889002 |
The molecular landscape of vascular cells in the human brain. | Crouch EE | Nature reviews. Cardiology | 39304749 | Nat Rev Cardiol | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39304749 |
Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain. | Crouch EE, Bhaduri A, Andrews MG, Cebrian-Silla A, Diafos LN, Birrueta JO, Wedderburn-Pugh K, Valenzuela EJ, Bennett NK, Eze UC, Sandoval-Espinosa C, Chen J, Mora C, Ross JM, Howard CE, Gonzalez-Granero S, Lozano JF, Vento M, Haeussler M, Paredes MF, Nakamura K, Garcia-Verdugo JM, Alvarez-Buylla A, Kriegstein AR, Huang EJ | Cell | 36179668 | Cell | 2022 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/36179668 |
Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy. | Choudhury A, Cady MA, Lucas CG, Najem H, Phillips JJ, Palikuqi B, Zakimi N, Joseph T, Birrueta JO, Chen WC, Oberheim Bush NA, Hervey-Jumper SL, Klein OD, Toedebusch CM, Horbinski CM, Magill ST, Bhaduri A, Perry A, Dickinson PJ, Heimberger AB, Ashworth A, Crouch EE, Raleigh DR | Cancer discovery | 38742767 | Cancer Discov | 2024 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/38742767 |
The promise of cerebral organoids for neonatology. | Howard CE, Cheenath M, Crouch EE | Current opinion in pediatrics | 40013913 | Curr Opin Pediatr | 2025 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/40013913 |
Gel-assisted mass spectrometry imaging enables sub-micrometer spatial lipidomics. | Chan YH, Pathmasiri KC, Pierre-Jacques D, Hibbard MC, Tao N, Fischer JL, Yang E, Cologna SM, Gao R | Nature communications | 38866734 | Nat Commun | 2024 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/38866734 |
Gel-assisted mass spectrometry imaging. | Chan YH, Pathmasiri KC, Pierre-Jacques D, Cologna SM, Gao R | bioRxiv : the preprint server for biology | 37398444 | bioRxiv | 2023 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/37398444 |
Axonal organelle buildup from loss of AP-4 complex function causes exacerbation of amyloid plaque pathology and gliosis in Alzheimer's disease mouse model. | Orlowski A, Karippaparambil J, Paumier JM, Ghanta S, Pallares E, Chandran R, Edmison D, Tandukar J, Gao R, Gowrishankar S | bioRxiv : the preprint server for biology | 38617351 | bioRxiv | 2024 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/38617351 |
Behavioral control through the direct, focal silencing of neuronal activity. | Elleman AV, Milicic N, Williams DJ, Simko J, Liu CJ, Haynes AL, Ehrlich DE, Makinson CD, Du Bois J | Cell chemical biology | 38729162 | Cell Chem Biol | 2024 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/38729162 |
Emerging roles of oligodendrocyte precursor cells in neural circuit development and remodeling. | Buchanan J, da Costa NM, Cheadle L | Trends in neurosciences | 37286422 | Trends Neurosci | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37286422 |
The cytokine receptor Fn14 is a molecular brake on neuronal activity that mediates circadian function in vivo. | Ferro A, Arshad A, Boyd L, Stanley T, Berisha A, Vrudhula U, Gomez AM, Borniger JC, Cheadle L | bioRxiv : the preprint server for biology | 38617238 | bioRxiv | 2024 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/38617238 |
Integrated high-confidence and high-throughput approaches for quantifying synapse engulfment by oligodendrocyte precursor cells. | Kahng JA, Xavier AM, Ferro A, Auguste YSS, Cheadle L | bioRxiv : the preprint server for biology | 37662250 | bioRxiv | 2023 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/37662250 |
High-confidence and high-throughput quantification of synapse engulfment by oligodendrocyte precursor cells. | Kahng JA, Xavier AM, Ferro A, Tang SX, Auguste YSS, Cheadle L | Nature protocols | 39363108 | Nat Protoc | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39363108 |
Disruption of Cholinergic Retinal Waves Alters Visual Cortex Development and Function. | Burbridge TJ, Ratliff JM, Dwivedi D, Vrudhula U, Alvarado-Huerta F, Sjulson L, Ibrahim LA, Cheadle L, Fishell G, Batista-Brito R | bioRxiv : the preprint server for biology | 38644996 | bioRxiv | 2024 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/38644996 |
A single-cell transcriptomic atlas of sensory-dependent gene expression in developing mouse visual cortex. | Xavier AM, Lin Q, Kang CJ, Cheadle L | bioRxiv : the preprint server for biology | 38979325 | bioRxiv | 2024 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/38979325 |
Open Access Data Repository and Common Data Model for Pulse Oximeter Performance Data. | Fong N, Lipnick MS, Behnke E, Chou Y, Elmankabadi S, Ortiz L, Almond CS, Auchus I, Burnett GW, Bisegerwa R, Conrad DR, Hendrickson CM, Hooli S, Kopotic R, Leeb G, Martin D, McCollum ED, Monk EP, Moore KL Jr, Shmuylovich L, Scott JB, Wong AI, Zhou T, Pirracchio R, Bickler PE, Feiner J, Law T | medRxiv : the preprint server for health sciences | 39252896 | medRxiv | 2024 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/39252896 |
The performance of 11 fingertip pulse oximeters during hypoxemia in healthy human participants with varied, quantified skin pigment. | Leeb G, Auchus I, Law T, Bickler P, Feiner J, Hashi S, Monk E, Igaga E, Bernstein M, Chou YC, Hughes C, Schornack D, Lester J, Moore K Jr, Okunlola O, Fernandez J, Shmuylovich L, Lipnick M | EBioMedicine | 38458110 | EBioMedicine | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38458110 |
Open Access Dataset and Common Data Model for Pulse Oximeter Performance Data. | Fong N, Lipnick MS, Behnke E, Chou Y, Elmankabadi S, Ortiz L, Almond CS, Auchus I, Burnett GW, Bisegerwa R, Conrad DR, Hendrickson CM, Hooli S, Kopotic R, Leeb G, Martin D, McCollum ED, Monk EP, Moore KL Jr, Shmuylovich L, Scott JB, Wong AI, Zhou T, Pirracchio R, Bickler PE, Feiner J, Law TJ | Scientific data | 40180919 | Sci Data | 2025 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/40180919 |
Comparison of methods for characterizing skin pigment diversity in research cohorts. | Lipnick MS, Chen D, Law T, Moore K Jr, Lester JC, Monk EP, Hendrickson CM, Chou Y, Hughes C, Behnke E, Elmankabadi S, Ortiz L, Negussie F, Leeb G, Ehie O, Auchus I, Igaga EN, Bisegerwa R, Okunlola O, Bickler P, Feiner J, Shmuylovich L | medRxiv : the preprint server for health sciences | 40061342 | medRxiv | 2025 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/40061342 |
Reimagining Cortical Connectivity by Deconstructing Its Molecular Logic into Building Blocks. | Chen X | Cold Spring Harbor perspectives in biology | 38621822 | Cold Spring Harb Perspect Biol | 2024 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/38621822 |
Cross-expression analysis reveals patterns of coordinated gene expression in spatial transcriptomics. | Sarwar A, Rue M, French L, Cross H, Chen X, Gillis J | bioRxiv : the preprint server for biology | 39345494 | bioRxiv | 2024 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/39345494 |
Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing. | Zhang A, Jin L, Yao S, Matsuyama M, van Velthoven CTJ, Sullivan HA, Sun N, Kellis M, Tasic B, Wickersham I, Chen X | eLife | 38319699 | Elife | 2024 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/38319699 |
Whole-cortex in situ sequencing reveals input-dependent area identity. | Chen X, Fischer S, Rue MCP, Zhang A, Mukherjee D, Kanold PO, Gillis J, Zador AM | Nature | 38658747 | Nature | 2024 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/38658747 |
Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing. | Zhang A, Jin L, Yao S, Matsuyama M, van Velthoven C, Sullivan H, Sun N, Kellis M, Tasic B, Wickersham IR, Chen X | bioRxiv : the preprint server for biology | 36993334 | bioRxiv | 2023 Nov 10 | https://www.ncbi.nlm.nih.gov/pubmed/36993334 |
xIV-LDDMM Toolkit: A Suite of Image-Varifold Based Technologies for Representing and Mapping 3D Imaging and Spatial-omics Data Simultaneously Across Scales. | Stouffer KM, Chen X, Zeng H, Charlier B, Younes L, Trouvé A, Miller MI | bioRxiv : the preprint server for biology | 39574713 | bioRxiv | 2024 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/39574713 |
Fluorogenic chemically induced dimerization. | Wang W, Shen J | Nature methods | 37640937 | Nat Methods | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37640937 |
Accessible and Generalizable in Vitro Luminescence Assay for Detecting GPCR Activation. | Miller RM, Sescil J, Sarcinella MC, Bailey RC, Wang W | ACS measurement science au | 37868356 | ACS Meas Sci Au | 2023 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/37868356 |
Protein-Based Tools for Studying Neuromodulation. | Wang W | ACS chemical biology | 38581649 | ACS Chem Biol | 2024 Apr 19 | https://www.ncbi.nlm.nih.gov/pubmed/38581649 |
Principles and Design of Molecular Tools for Sensing and Perturbing Cell Surface Receptor Activity. | Sescil J, Havens SM, Wang W | Chemical reviews | 39999110 | Chem Rev | 2025 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/39999110 |
Genetically encoded tools for in vivo G-protein-coupled receptor agonist detection at cellular resolution. | Kroning KE, Wang W | Clinical and translational medicine | 36446954 | Clin Transl Med | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36446954 |
A general method for chemogenetic control of peptide function. | Shen J, Geng L, Li X, Emery C, Kroning K, Shingles G, Lee K, Heyden M, Li P, Wang W | Nature methods | 36481965 | Nat Methods | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36481965 |
Functionalization of a versatile fluorescent sensor for detecting protease activity and temporally gated opioid sensing. | Sescil J, Fiel H, Havens SM, Fu E, Li X, Kroning KE, Solowiej I, Li P, Wang W | RSC chemical biology | 39975583 | RSC Chem Biol | 2025 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/39975583 |
Protein Engineering for Spatiotemporally Resolved Cellular Monitoring. | Zhou G, Wang W | Annual review of analytical chemistry (Palo Alto, Calif.) | 39999860 | Annu Rev Anal Chem (Palo Alto Calif) | 2025 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/39999860 |
Measuring internalized health-related stigma across health conditions: development and validation of the I-HEARTS Scale. | Pearl RL, Li Y, Groshon LC, Hernandez M, Saunders D, Sheynblyum M, Driscoll KA, Gelfand JM, Manavalan P, Montanez-Wiscovich M, Pereira DB, Puhl RM, Wadden TA, Waxenberg LB, Westen SC, Lou XY | BMC medicine | 39379928 | BMC Med | 2024 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/39379928 |
Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination. | Pan L, Trimarco A, Zhang AJ, Fujimori K, Urade Y, Sun LO, Taveggia C, Zhang Y | eLife | 36779701 | Elife | 2023 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/36779701 |
A luciferase fragment complementation assay to detect focal adhesion kinase (FAK) signaling events. | Estep JA, Sun LO, Riccomagno MM | Heliyon | 37089315 | Heliyon | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37089315 |
Autophagy collaborates with apoptosis pathways to control oligodendrocyte number. | Zhang T, Bhambri A, Zhang Y, Barbosa D, Bae HG, Xue J, Wazir S, Mulinyawe SB, Kim JH, Sun LO | Cell reports | 37543947 | Cell Rep | 2023 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/37543947 |
Genetically Labeled Premyelinating Oligodendrocytes: Bridging Oligodendrogenesis and Neuronal Activity. | Bhambri A, Thai P, Wei S, Bae HG, Barbosa D, Sharma T, Yu Z, Xing C, Kim JH, Yu G, Sun LO | bioRxiv : the preprint server for biology | 39763780 | bioRxiv | 2024 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/39763780 |
Autophagy collaborates with apoptosis pathways to control myelination specificity and function. | Zhang T, Bae HG, Bhambri A, Zhang Y, Barbosa D, Xue J, Wazir S, Mulinyawe SB, Kim JH, Sun LO | bioRxiv : the preprint server for biology | 36712125 | bioRxiv | 2023 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/36712125 |
Gene expansions contributing to human brain evolution. | Soto DC, Uribe-Salazar JM, Kaya G, Valdarrago R, Sekar A, Haghani NK, Hino K, La GN, Mariano NAF, Ingamells C, Baraban AE, Turner TN, Green ED, Simó S, Quon G, Andrés AM, Dennis MY | bioRxiv : the preprint server for biology | 39386494 | bioRxiv | 2024 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/39386494 |
scPair: Boosting single cell multimodal analysis by leveraging implicit feature selection and single cell atlases. | Hu H, Quon G | Nature communications | 39548084 | Nat Commun | 2024 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/39548084 |
MiniXL: An open-source, large field-of-view epifluorescence miniature microscope for mice capable of single-cell resolution and multi-brain region imaging. | Zhao P, Guo C, Xie M, Chen L, Golshani P, Aharoni D | bioRxiv : the preprint server for biology | 39229051 | bioRxiv | 2024 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/39229051 |
A nociceptive amygdala-striatal pathway for chronic pain aversion. | Wojick JA, Paranjapye A, Chiu JK, Mahmood M, Oswell C, Kimmey BA, Wooldridge LM, McCall NM, Han A, Ejoh LL, Chehimi SN, Crist RC, Reiner BC, Korb E, Corder G | bioRxiv : the preprint server for biology | 38405972 | bioRxiv | 2024 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/38405972 |
SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry. | Kee J, Thudium S, Renner DM, Glastad K, Palozola K, Zhang Z, Li Y, Lan Y, Cesare J, Poleshko A, Kiseleva AA, Truitt R, Cardenas-Diaz FL, Zhang X, Xie X, Kotton DN, Alysandratos KD, Epstein JA, Shi PY, Yang W, Morrisey E, Garcia BA, Berger SL, Weiss SR, Korb E | Nature | 36198800 | Nature | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36198800 |
Loss of DOT1L function disrupts neuronal transcription, animal behavior, and leads to a novel neurodevelopmental disorder. | Maroni MJ, Barton M, Lynch K, Deshwar AR, Campbell P, Millard J, Lee R, Cohen A, Paranjapye A, Faundes V, Repetto GM, McKenna C, Shillington AL, Phornphutkul C, Mancini GM, Schot R, Barakat TS, Richmond CM, Lauzon J, Elsayed Ibrahim AI, Benito DN, Ortez C, Estevez-Arias B, Lecoquierre F, Cassinari K, Guerrot AM, Levy J, Latypova X, Verloes A, Innes AM, Yang XR, Banka S, Vill K, Jacob M, Kruer M, Skidmore P, Galaz-Montoya CI, Bakhtiari S, Mester JL, Granato M, Armache KJ, Costain G, Korb E | medRxiv : the preprint server for health sciences | 39574879 | medRxiv | 2024 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/39574879 |
Control of striatal circuit development by the chromatin regulator Zswim6. | Choi K, Henderson NT, Feierman ER, Louzon S, Galanaugh J, Davatolhagh F, Bhandaru I, Tischfield DJ, Anderson SA, Korb E, Fuccillo MV | Science advances | 39823338 | Sci Adv | 2025 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/39823338 |
Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long-term memory. | Feierman ER, Louzon S, Prescott NA, Biaco T, Gao Q, Qiu Q, Choi K, Palozola KC, Voss AJ, Mehta SD, Quaye CN, Lynch KT, Fuccillo MV, Wu H, David Y, Korb E | bioRxiv : the preprint server for biology | 38352334 | bioRxiv | 2024 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/38352334 |
Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long-term memory. | Feierman ER, Louzon S, Prescott NA, Biaco T, Gao Q, Qiu Q, Choi K, Palozola KC, Voss AJ, Mehta SD, Quaye CN, Lynch KT, Fuccillo MV, Wu H, David Y, Korb E | Molecular cell | 39025074 | Mol Cell | 2024 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/39025074 |
Identification of a transcriptional signature found in multiple models of ASD and related disorders. | Thudium S, Palozola K, L'Her É, Korb E | Genome research | 36104286 | Genome Res | 2022 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/36104286 |
Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling. | Feierman ER, Paranjapye A, Su S, Qiu Q, Wu H, Korb E | bioRxiv : the preprint server for biology | 39553997 | bioRxiv | 2024 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/39553997 |
Differences in Beliefs About Suicide by Occupation in a Representative Sample of Adults in the United States, General Social Survey 2002-2021. | Blosnich JR, Haydinger AM, Rhoades H, De Luca SM | Archives of suicide research : official journal of the International Academy for Suicide Research | 36916390 | Arch Suicide Res | 2024 Apr-Jun | https://www.ncbi.nlm.nih.gov/pubmed/36916390 |
Concept Analysis: Challenge Coins as a Caring Support Tool to Prevent Farmer Suicide. | Ward JM, Blosnich JR, Dean-Witt C | Journal of agromedicine | 39440398 | J Agromedicine | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39440398 |
Adverse Childhood Experiences Among Lesbian, Gay, Bisexual, and Queer Veterans. | Hahn HA, Blosnich JR | American journal of preventive medicine | 37037327 | Am J Prev Med | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37037327 |
Interpersonal and self-directed violence among sexual and gender minority populations: Moving research from prevalence to prevention. | Blosnich JR | Current epidemiology reports | 36845319 | Curr Epidemiol Rep | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36845319 |
Medial entorhinal cortex mediates learning of context-dependent interval timing behavior. | Bigus ER, Lee HW, Bowler JC, Shi J, Heys JG | Nature neuroscience | 38877306 | Nat Neurosci | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38877306 |
Medial entorhinal cortex plays a specialized role in learning of flexible, context-dependent interval timing behavior. | Bigus ER, Lee HW, Shi J, Heys JG | Research square | 37131646 | Res Sq | 2023 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/37131646 |
Sensitivity optimization of a rhodopsin-based fluorescent voltage indicator. | Abdelfattah AS, Zheng J, Singh A, Huang YC, Reep D, Tsegaye G, Tsang A, Arthur BJ, Rehorova M, Olson CVL, Shuai Y, Zhang L, Fu TM, Milkie DE, Moya MV, Weber TD, Lemire AL, Baker CA, Falco N, Zheng Q, Grimm JB, Yip MC, Walpita D, Chase M, Campagnola L, Murphy GJ, Wong AM, Forest CR, Mertz J, Economo MN, Turner GC, Koyama M, Lin BJ, Betzig E, Novak O, Lavis LD, Svoboda K, Korff W, Chen TW, Schreiter ER, Hasseman JP, Kolb I | Neuron | 37015225 | Neuron | 2023 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/37015225 |
Neurophotonic tools for microscopic measurements and manipulation: status report. | Abdelfattah AS, Ahuja S, Akkin T, Allu SR, Brake J, Boas DA, Buckley EM, Campbell RE, Chen AI, Cheng X, Čižmár T, Costantini I, De Vittorio M, Devor A, Doran PR, El Khatib M, Emiliani V, Fomin-Thunemann N, Fainman Y, Fernandez-Alfonso T, Ferri CGL, Gilad A, Han X, Harris A, Hillman EMC, Hochgeschwender U, Holt MG, Ji N, Kılıç K, Lake EMR, Li L, Li T, Mächler P, Miller EW, Mesquita RC, Nadella KMNS, Nägerl UV, Nasu Y, Nimmerjahn A, Ondráčková P, Pavone FS, Perez Campos C, Peterka DS, Pisano F, Pisanello F, Puppo F, Sabatini BL, Sadegh S, Sakadzic S, Shoham S, Shroff SN, Silver RA, Sims RR, Smith SL, Srinivasan VJ, Thunemann M, Tian L, Tian L, Troxler T, Valera A, Vaziri A, Vinogradov SA, Vitale F, Wang LV, Uhlířová H, Xu C, Yang C, Yang MH, Yellen G, Yizhar O, Zhao Y | Neurophotonics | 35493335 | Neurophotonics | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/35493335 |
A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo. | Villette V, Yang S, Valenti R, Macklin JJ, Bradley J, Mathieu B, Lombardini A, Podgorski K, Dieudonné S, Schreiter ER, Abdelfattah AS | bioRxiv : the preprint server for biology | 39605646 | bioRxiv | 2024 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/39605646 |
Unsupervised learning of stationary and switching dynamical system models from Poisson observations. | Song CY, Shanechi MM | Journal of neural engineering | 38083862 | J Neural Eng | 2023 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/38083862 |
Dynamical flexible inference of nonlinear latent factors and structures in neural population activity. | Abbaspourazad H, Erturk E, Pesaran B, Shanechi MM | Nature biomedical engineering | 38082181 | Nat Biomed Eng | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/38082181 |
Multimodal subspace identification for modeling discrete-continuous spiking and field potential population activity. | Ahmadipour P, Sani OG, Pesaran B, Shanechi MM | Journal of neural engineering | 38016450 | J Neural Eng | 2024 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/38016450 |
Modeling multiscale causal interactions between spiking and field potential signals during behavior. | Wang C, Pesaran B, Shanechi MM | Journal of neural engineering | 35073530 | J Neural Eng | 2022 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/35073530 |
Modeling and dissociation of intrinsic and input-driven neural population dynamics underlying behavior. | Vahidi P, Sani OG, Shanechi MM | Proceedings of the National Academy of Sciences of the United States of America | 38335258 | Proc Natl Acad Sci U S A | 2024 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/38335258 |
Challenges and opportunities of acquiring cortical recordings for chronic adaptive deep brain stimulation. | Herron J, Kullmann A, Denison T, Goodman WK, Gunduz A, Neumann WJ, Provenza NR, Shanechi MM, Sheth SA, Starr PA, Widge AS | Nature biomedical engineering | 39730913 | Nat Biomed Eng | 2024 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/39730913 |
Dissociative and prioritized modeling of behaviorally relevant neural dynamics using recurrent neural networks. | Sani OG, Pesaran B, Shanechi MM | Nature neuroscience | 39242944 | Nat Neurosci | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39242944 |
Single Cell Transcriptome of Stress Vulnerability Network in mouse Prefrontal Cortex. | Hing B, Mitchell SB, Eberle M, Filali Y, Hultman I, Matkovich M, Kasturirangan M, Wyche W, Jimenez A, Velamuri R, Johnson M, Srivastava S, Hultman R | bioRxiv : the preprint server for biology | 37662266 | bioRxiv | 2023 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/37662266 |
Transcriptomic Evaluation of a Stress Vulnerability Network Using Single-Cell RNA Sequencing in Mouse Prefrontal Cortex. | Hing B, Mitchell SB, Filali Y, Eberle M, Hultman I, Matkovich M, Kasturirangan M, Johnson M, Wyche W, Jimenez A, Velamuri R, Ghumman M, Wickramasinghe H, Christian O, Srivastava S, Hultman R | Biological psychiatry | 38866174 | Biol Psychiatry | 2024 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/38866174 |
An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies. | McCutcheon N, Johnson MS, Rea B, Ghumman M, Sowers L, Hultman R | Journal of visualized experiments : JoVE | 39555788 | J Vis Exp | 2024 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/39555788 |
Distinct value computations support rapid sequential decisions. | Mah A, Schiereck SS, Bossio V, Constantinople CM | Nature communications | 37989741 | Nat Commun | 2023 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/37989741 |
Dopamine transients encode reward prediction errors independent of learning rates. | Mah A, Golden CEM, Constantinople CM | Cell reports | 39395170 | Cell Rep | 2024 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/39395170 |
Acetylcholine demixes heterogeneous dopamine signals for learning and moving. | Jang HJ, Ward RM, Golden CEM, Constantinople CM | bioRxiv : the preprint server for biology | 38746300 | bioRxiv | 2024 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/38746300 |
Neural dynamics in the orbitofrontal cortex reveal cognitive strategies. | Schiereck SS, Pérez-Rivera DT, Mah A, DeMaegd ML, Ward RM, Hocker D, Savin C, Constantinople CM | bioRxiv : the preprint server for biology | 39554155 | bioRxiv | 2024 Oct 29 | https://www.ncbi.nlm.nih.gov/pubmed/39554155 |
Distinct value computations support rapid sequential decisions. | Mah A, Schiereck SS, Bossio V, Constantinople CM | bioRxiv : the preprint server for biology | 36993514 | bioRxiv | 2023 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/36993514 |
Dopamine transients encode reward prediction errors independent of learning rates. | Mah A, Golden CEM, Constantinople CM | bioRxiv : the preprint server for biology | 38659861 | bioRxiv | 2024 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/38659861 |
SLEAP: A deep learning system for multi-animal pose tracking. | Pereira TD, Tabris N, Matsliah A, Turner DM, Li J, Ravindranath S, Papadoyannis ES, Normand E, Deutsch DS, Wang ZY, McKenzie-Smith GC, Mitelut CC, Castro MD, D'Uva J, Kislin M, Sanes DH, Kocher SD, Wang SS, Falkner AL, Shaevitz JW, Murthy M | Nature methods | 35379947 | Nat Methods | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35379947 |
Aggression experience and observation promote shared behavioral and neural changes. | Iravedra-Garcia JM, Guthman EM, Cuturela L, Ocasio-Arce EJ, Pillow JW, Falkner AL | bioRxiv : the preprint server for biology | 39763843 | bioRxiv | 2024 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/39763843 |
Neural mechanisms of persistent aggression. | Guthman EM, Falkner AL | Current opinion in neurobiology | 35344844 | Curr Opin Neurobiol | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35344844 |
Behavioural and dopaminergic signatures of resilience. | Willmore L, Cameron C, Yang J, Witten IB, Falkner AL | Nature | 36261520 | Nature | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/36261520 |
Independent inhibitory control mechanisms for aggressive motivation and action. | Minakuchi T, Guthman EM, Acharya P, Hinson J, Fleming W, Witten IB, Oline SN, Falkner AL | Nature neuroscience | 38347201 | Nat Neurosci | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38347201 |
Toward a neurobiological model of human performance under pressure. | Saikley A, Haroush K | Proceedings of the National Academy of Sciences of the United States of America | 34470823 | Proc Natl Acad Sci U S A | 2021 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/34470823 |
Microanalytical Mass Spectrometry with Super-Resolution Microscopy Reveals a Proteome Transition During Development of the Brain's Circadian Pacemaker. | Choi SB, Vatan T, Alexander TA, Zhang C, Mitchell SM, Speer CM, Nemes P | Analytical chemistry | 37792996 | Anal Chem | 2023 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/37792996 |
Volumetric super-resolution imaging by serial ultrasectioning and stochastic optical reconstruction microscopy in mouse neural tissue. | Vatan T, Minehart JA, Zhang C, Agarwal V, Yang J, Speer CM | STAR protocols | 34901889 | STAR Protoc | 2021 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/34901889 |
A Picture Worth a Thousand Molecules-Integrative Technologies for Mapping Subcellular Molecular Organization and Plasticity in Developing Circuits. | Minehart JA, Speer CM | Frontiers in synaptic neuroscience | 33469427 | Front Synaptic Neurosci | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33469427 |
Rapid 3D-STORM imaging of diverse molecular targets in tissue. | Albrecht NE, Jiang D, Akhanov V, Hobson R, Speer CM, Robichaux MA, Samuel MA | Cell reports methods | 35880013 | Cell Rep Methods | 2022 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/35880013 |
The synaptic basis of activity-dependent eye-specific competition. | Zhang C, Yadav S, Speer CM | Cell reports | 36753422 | Cell Rep | 2023 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/36753422 |
A pheromone receptor in cichlid fish mediates attraction to females but inhibits male parental care. | Li CY, Bowers JM, Alexander TA, Behrens KA, Jackson P, Amini CJ, Juntti SA | Current biology : CB | 39094572 | Curr Biol | 2024 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/39094572 |
Activity-dependent synapse clustering underlies eye-specific competition in the developing retinogeniculate system. | Zhang C, Vatan T, Speer CM | bioRxiv : the preprint server for biology | 39484601 | bioRxiv | 2024 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/39484601 |
Plasmodium falciparum infection in humans and mosquitoes influence natural Anopheline biting behavior and transmission. | Markwalter CF, Lapp Z, Abel L, Kimachas E, Omollo E, Freedman E, Chepkwony T, Amunga M, McCormick T, Bérubé S, Mangeni JN, Wesolowski A, Obala AA, Taylor SM, Prudhomme O'Meara W | Nature communications | 38816383 | Nat Commun | 2024 May 30 | https://www.ncbi.nlm.nih.gov/pubmed/38816383 |
Consistently estimating network statistics using aggregated relational data. | Breza E, Chandrasekhar AG, Lubold S, McCormick TH, Pan M | Proceedings of the National Academy of Sciences of the United States of America | 37192169 | Proc Natl Acad Sci U S A | 2023 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/37192169 |
Using Aggregated Relational Data to Feasibly Identify Network Structure without Network Data. | Breza E, Chandrasekhar AG, McCormick TH, Pan M | The American economic review | 34526729 | Am Econ Rev | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34526729 |
Using Bayesian Latent Gaussian Graphical Models to Infer Symptom Associations in Verbal Autopsies. | Li ZR, McComick TH, Clark SJ | Bayesian analysis | 33273996 | Bayesian Anal | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/33273996 |
Comparing the Robustness of Simple Network Scale-Up Method Estimators. | Kunke JP, Laga I, Niu X, McCormick TH | Sociological methodology | 39391075 | Sociol Methodol | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/39391075 |
Quantifying heterogeneity in SARS-CoV-2 transmission during the lockdown in India. | Arinaminpathy N, Das J, McCormick TH, Mukhopadhyay P, Sircar N | Epidemics | 34171509 | Epidemics | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34171509 |
Quantifying heterogeneity in SARS-CoV-2 transmission during the lockdown in India. | Arinaminpathy N, Das J, McCormick TH, Mukhopadhyay P, Sircar N | medRxiv : the preprint server for health sciences | 32995809 | medRxiv | 2020 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/32995809 |
Methods for correcting inference based on outcomes predicted by machine learning. | Wang S, McCormick TH, Leek JT | Proceedings of the National Academy of Sciences of the United States of America | 33208538 | Proc Natl Acad Sci U S A | 2020 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/33208538 |
A FLEXIBLE BAYESIAN FRAMEWORK TO ESTIMATE AGE- AND CAUSE-SPECIFIC CHILD MORTALITY OVER TIME FROM SAMPLE REGISTRATION DATA. | Schumacher AE, McCormick TH, Wakefield J, Chu Y, Perin J, Villavicencio F, Simon N, Liu L | The annals of applied statistics | 37621750 | Ann Appl Stat | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/37621750 |
ipd: an R package for conducting inference on predicted data. | Salerno S, Miao J, Afiaz A, Hoffman K, Neufeld A, Lu Q, McCormick TH, Leek JT | Bioinformatics (Oxford, England) | 39898809 | Bioinformatics | 2025 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/39898809 |
Arousal and Locomotion Differently Modulate Activity of Somatostatin Neurons across Cortex. | Khoury CF, Fala NG, Runyan CA | eNeuro | 37169583 | eNeuro | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37169583 |
Simultaneous interneuron labeling reveals cell type-specific, population-level interactions in cortex. | Potter CT, Bassi CD, Runyan CA | iScience | 39280622 | iScience | 2024 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/39280622 |
Different state-dependence of population codes across cortex. | Bandi AC, Runyan CA | bioRxiv : the preprint server for biology | 38826351 | bioRxiv | 2024 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/38826351 |
Local Differences in Network Organization in the Auditory and Parietal Cortex, Revealed with Single Neuron Activation. | Khoury CF, Ferrone M, Runyan CA | The Journal of neuroscience : the official journal of the Society for Neuroscience | 39890466 | J Neurosci | 2025 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/39890466 |
The spatial scale of somatostatin subnetworks increases from sensory to association cortex. | Khoury CF, Fala NG, Runyan CA | Cell reports | 36070697 | Cell Rep | 2022 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/36070697 |
Simultaneous interneuron labeling reveals population-level interactions among parvalbumin, somatostatin, and pyramidal neurons in cortex. | Potter C, Bassi C, Runyan CA | bioRxiv : the preprint server for biology | 36711788 | bioRxiv | 2024 Feb 2 | https://www.ncbi.nlm.nih.gov/pubmed/36711788 |
Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants. | McAfee JC, Lee S, Lee J, Bell JL, Krupa O, Davis J, Insigne K, Bond ML, Zhao N, Boyle AP, Phanstiel DH, Love MI, Stein JL, Ruzicka WB, Davila-Velderrain J, Kosuri S, Won H | Cell genomics | 37868037 | Cell Genom | 2023 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/37868037 |
A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles. | Sey NYA, Hu B, Mah W, Fauni H, McAfee JC, Rajarajan P, Brennand KJ, Akbarian S, Won H | Nature neuroscience | 32152537 | Nat Neurosci | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32152537 |
Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism. | Matoba N, Liang D, Sun H, Aygün N, McAfee JC, Davis JE, Raffield LM, Qian H, Piven J, Li Y, Kosuri S, Won H, Stein JL | Translational psychiatry | 32747698 | Transl Psychiatry | 2020 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/32747698 |
Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders. | Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S, PsychENCODE Consortium, Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH | Nature communications | 34172755 | Nat Commun | 2021 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/34172755 |
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia. | Wen J, Trost B, Engchuan W, Halvorsen M, Pallotto LM, Mitina A, Ancalade N, Farrell M, Backstrom I, Guo K, Pellecchia G, Thiruvahindrapuram B, Giusti-Rodriguez P, Rosen JD, Li Y, Won H, Magnusson PKE, Gyllensten U, Bassett AS, Hultman CM, Sullivan PF, Yuen RKC, Szatkiewicz JP | Molecular psychiatry | 36380236 | Mol Psychiatry | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36380236 |
Annotating genetic variants to target genes using H-MAGMA. | Sey NYA, Pratt BM, Won H | Nature protocols | 36289406 | Nat Protoc | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36289406 |
Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features. | Bond ML, Davis ES, Quiroga IY, Dey A, Kiran M, Love MI, Won H, Phanstiel DH | Genome research | 37699658 | Genome Res | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37699658 |
Regulatory landscape in brain development and disease. | Spiess K, Won H | Current opinion in genetics & development | 32563855 | Curr Opin Genet Dev | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32563855 |
Focus on your locus with a massively parallel reporter assay. | McAfee JC, Bell JL, Krupa O, Matoba N, Stein JL, Won H | Journal of neurodevelopmental disorders | 36085003 | J Neurodev Disord | 2022 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/36085003 |
Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex. | Liu S, Won H, Clarke D, Matoba N, Khullar S, Mu Y, Wang D, Gerstein M | Genome medicine | 36424644 | Genome Med | 2022 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/36424644 |
Advances in profiling chromatin architecture shed light on the regulatory dynamics underlying brain disorders. | Pratt BM, Won H | Seminars in cell & developmental biology | 34483043 | Semin Cell Dev Biol | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34483043 |
Schizophrenia-Linked Protein tSNARE1 Regulates Endosomal Trafficking in Cortical Neurons. | Plooster M, Rossi G, Farrell MS, McAfee JC, Bell JL, Ye M, Diering GH, Won H, Gupton SL, Brennwald P | The Journal of neuroscience : the official journal of the Society for Neuroscience | 34642214 | J Neurosci | 2021 Nov 10 | https://www.ncbi.nlm.nih.gov/pubmed/34642214 |
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. | Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, Zellers S, Sherva R, Aliev F, Nothnagel M, Young KA, Marks JA, Young H, Carnes MU, Guo Y, Waldrop A, Sey NYA, Landi MT, McNeil DW, Drichel D, Farrer LA, Markunas CA, Vink JM, Hottenga JJ, Iacono WG, Kranzler HR, Saccone NL, Neale MC, Madden P, Rietschel M, Marazita ML, McGue M, Won H, Winterer G, Grucza R, Dick DM, Gelernter J, Caporaso NE, Baker TB, Boomsma DI, Kaprio J, Hokanson JE, Vrieze S, Bierut LJ, Johnson EO, Hancock DB | Nature communications | 33144568 | Nat Commun | 2020 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/33144568 |
Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism. | Ramaswami G, Won H, Gandal MJ, Haney J, Wang JC, Wong CCY, Sun W, Prabhakar S, Mill J, Geschwind DH | Nature communications | 32978376 | Nat Commun | 2020 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/32978376 |
Chromatin architecture provides a roadmap to improve our understanding of psychiatric disorders. | Hu B, Won H | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 32859998 | Neuropsychopharmacology | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32859998 |
Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits. | Sey NYA, Hu B, Iskhakova M, Lee S, Sun H, Shokrian N, Ben Hutta G, Marks JA, Quach BC, Johnson EO, Hancock DB, Akbarian S, Won H | Molecular psychiatry | 35422469 | Mol Psychiatry | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35422469 |
Limited Association between Schizophrenia Genetic Risk Factors and Transcriptomic Features. | Yu AW, Peery JD, Won H | Genes | 34356078 | Genes (Basel) | 2021 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/34356078 |
HIV integration in the human brain is linked to microglial activation and 3D genome remodeling. | Plaza-Jennings AL, Valada A, O'Shea C, Iskhakova M, Hu B, Javidfar B, Ben Hutta G, Lambert TY, Murray J, Kassim B, Chandrasekaran S, Chen BK, Morgello S, Won H, Akbarian S | Molecular cell | 36525955 | Mol Cell | 2022 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/36525955 |
Convergence and Divergence of Rare Genetic Disorders on Brain Phenotypes: A Review. | Raznahan A, Won H, Glahn DC, Jacquemont S | JAMA psychiatry | 35767289 | JAMA Psychiatry | 2022 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/35767289 |
Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. | Lee S, McAfee JC, Lee J, Gomez A, Ledford AT, Clarke D, Min H, Gerstein MB, Boyle AP, Sullivan PF, Beltran AS, Won H | Cell | 39848247 | Cell | 2025 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/39848247 |
Viscera affectum anno: the gut beyond eating behaviours. | Bohórquez DV | Nature reviews. Gastroenterology & hepatology | 33262502 | Nat Rev Gastroenterol Hepatol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33262502 |
Deciphering visceral instincts: a scientific quest to unravel food choices from molecules to mind. | Alway E, Reicher N, Bohórquez DV | Genes & development | 39362782 | Genes Dev | 2024 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/39362782 |
The preference for sugar over sweetener depends on a gut sensor cell. | Buchanan KL, Rupprecht LE, Kaelberer MM, Sahasrabudhe A, Klein ME, Villalobos JA, Liu WW, Yang A, Gelman J, Park S, Anikeeva P, Bohórquez DV | Nature neuroscience | 35027761 | Nat Neurosci | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35027761 |
The nerve not taken. | Rupprecht LE, Bohórquez DV | Cell metabolism | 33657390 | Cell Metab | 2021 Mar 2 | https://www.ncbi.nlm.nih.gov/pubmed/33657390 |
Neuropod Cells: The Emerging Biology of Gut-Brain Sensory Transduction. | Kaelberer MM, Rupprecht LE, Liu WW, Weng P, Bohórquez DV | Annual review of neuroscience | 32101483 | Annu Rev Neurosci | 2020 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/32101483 |
Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits. | Sahasrabudhe A, Rupprecht LE, Orguc S, Khudiyev T, Tanaka T, Sands J, Zhu W, Tabet A, Manthey M, Allen H, Loke G, Antonini MJ, Rosenfeld D, Park J, Garwood IC, Yan W, Niroui F, Fink Y, Chandrakasan A, Bohórquez DV, Anikeeva P | Nature biotechnology | 37349522 | Nat Biotechnol | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37349522 |
The neural basis of sugar preference. | Liu WW, Bohórquez DV | Nature reviews. Neuroscience | 35879409 | Nat Rev Neurosci | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/35879409 |
Dopamine, Updated: Reward Prediction Error and Beyond. | Lerner TN, Holloway AL, Seiler JL | Current opinion in neurobiology | 33197709 | Curr Opin Neurobiol | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33197709 |
Parvalbumin(+) and Npas1(+) Pallidal Neurons Have Distinct Circuit Topology and Function. | Pamukcu A, Cui Q, Xenias HS, Berceau BL, Augustine EC, Fan I, Chalasani S, Hantman AW, Lerner TN, Boca SM, Chan CS | The Journal of neuroscience : the official journal of the Society for Neuroscience | 32868462 | J Neurosci | 2020 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/32868462 |
Dopamine signaling in the dorsomedial striatum promotes compulsive behavior. | Seiler JL, Cosme CV, Sherathiya VN, Schaid MD, Bianco JM, Bridgemohan AS, Lerner TN | Current biology : CB | 35134327 | Curr Biol | 2022 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/35134327 |
Interfacing behavioral and neural circuit models for habit formation. | Lerner TN | Journal of neuroscience research | 31916623 | J Neurosci Res | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31916623 |
Editorial: Dopamine Neuron Diversity in Circuits and Diseases. | Poulin JF, Lerner TN, Howe MW | Frontiers in neural circuits | 35310549 | Front Neural Circuits | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35310549 |
GuPPy, a Python toolbox for the analysis of fiber photometry data. | Sherathiya VN, Schaid MD, Seiler JL, Lopez GC, Lerner TN | Scientific reports | 34930955 | Sci Rep | 2021 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/34930955 |
Hidden variables in stress neurobiology research. | Holloway AL, Lerner TN | Trends in neurosciences | 37985263 | Trends Neurosci | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/37985263 |
Chronically dysregulated corticosterone impairs dopaminergic transmission in the dorsomedial striatum by sex-divergent mechanisms. | Holloway AL, Schaid MD, Lerner TN | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 36810463 | Neuropsychopharmacology | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/36810463 |
How Dopamine Enables Learning from Aversion. | Lopez GC, Lerner TN | Current opinion in behavioral sciences | 39719969 | Curr Opin Behav Sci | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39719969 |
Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution. | Pollen AA, Kilik U, Lowe CB, Camp JG | Nature reviews. Genetics | 36737647 | Nat Rev Genet | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36737647 |
INTERSPECIES ORGANOIDS REVEAL HUMAN-SPECIFIC MOLECULAR FEATURES OF DOPAMINERGIC NEURON DEVELOPMENT AND VULNERABILITY. | Nolbrant S, Wallace JL, Ding J, Zhu T, Sevetson JL, Kajtez J, Baldacci IA, Corrigan EK, Hoglin K, McMullen R, Schmitz MT, Breevoort A, Swope D, Wu F, Pavlovic BJ, Salama SR, Kirkeby A, Huang H, Schaefer NK, Pollen AA | bioRxiv : the preprint server for biology | 39605599 | bioRxiv | 2024 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/39605599 |
Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex. | Deng C, Whalen S, Steyert M, Ziffra R, Przytycki PF, Inoue F, Pereira DA, Capauto D, Norton S, Vaccarino FM, Pollen A, Nowakowski TJ, Ahituv N, Pollard KS | bioRxiv : the preprint server for biology | 36824845 | bioRxiv | 2023 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/36824845 |
Three-dimensional genome rewiring in loci with human accelerated regions. | Keough KC, Whalen S, Inoue F, Przytycki PF, Fair T, Deng C, Steyert M, Ryu H, Lindblad-Toh K, Karlsson E, Zoonomia Consortium§, Nowakowski T, Ahituv N, Pollen A, Pollard KS | Science (New York, N.Y.) | 37104607 | Science | 2023 Apr 28 | https://www.ncbi.nlm.nih.gov/pubmed/37104607 |
Mapping cis- and trans-regulatory target genes of human-specific deletions. | Fair T, Pavlovic BJ, Swope D, Castillo OE, Schaefer NK, Pollen AA | bioRxiv : the preprint server for biology | 38234800 | bioRxiv | 2024 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/38234800 |
Rethinking nomenclature for interspecies cell fusions. | Pavlovic BJ, Fox D, Schaefer NK, Pollen AA | Nature reviews. Genetics | 35082442 | Nat Rev Genet | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35082442 |
UCSC Cell Browser: visualize your single-cell data. | Speir ML, Bhaduri A, Markov NS, Moreno P, Nowakowski TJ, Papatheodorou I, Pollen AA, Raney BJ, Seninge L, Kent WJ, Haeussler M | Bioinformatics (Oxford, England) | 34244710 | Bioinformatics | 2021 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/34244710 |
Comparative landscape of genetic dependencies in human and chimpanzee stem cells. | She R, Fair T, Schaefer NK, Saunders RA, Pavlovic BJ, Weissman JS, Pollen AA | bioRxiv : the preprint server for biology | 36993685 | bioRxiv | 2023 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/36993685 |
Genetic architecture of human brain evolution. | Fair T, Pollen AA | Current opinion in neurobiology | 37003107 | Curr Opin Neurobiol | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37003107 |
Machine learning dissection of human accelerated regions in primate neurodevelopment. | Whalen S, Inoue F, Ryu H, Fair T, Markenscoff-Papadimitriou E, Keough K, Kircher M, Martin B, Alvarado B, Elor O, Laboy Cintron D, Williams A, Hassan Samee MA, Thomas S, Krencik R, Ullian EM, Kriegstein A, Rubenstein JL, Shendure J, Pollen AA, Ahituv N, Pollard KS | Neuron | 36640767 | Neuron | 2023 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/36640767 |
Comparative landscape of genetic dependencies in human and chimpanzee stem cells. | She R, Fair T, Schaefer NK, Saunders RA, Pavlovic BJ, Weissman JS, Pollen AA | Cell | 37343560 | Cell | 2023 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/37343560 |
Reverse engineering human brain evolution using organoid models. | Mostajo-Radji MA, Schmitz MT, Montoya ST, Pollen AA | Brain research | 31809699 | Brain Res | 2020 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/31809699 |
Conservation, alteration, and redistribution of mammalian striatal interneurons. | Corrigan EK, DeBerardine M, Poddar A, Turrero García M, Schmitz MT, Harwell CC, Paredes MF, Krienen FM, Pollen AA | bioRxiv : the preprint server for biology | 39131311 | bioRxiv | 2024 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/39131311 |
The lab on lockdown: thinking back and looking ahead. | Poe GR, Cai DJ | Nature reviews. Neuroscience | 32699293 | Nat Rev Neurosci | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32699293 |
Chronotate: An open-source tool for manual timestamping and quantification of animal behavior. | Philipsberg PA, Christenson Wick Z, Diego KS, Vaughan N, Galas A, Jurkowski A, Feng Y, Vetere LM, Chen L, Soler I, Cai DJ, Shuman T | Neuroscience letters | 37619698 | Neurosci Lett | 2023 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/37619698 |
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior. | Blaze J, Navickas A, Phillips HL, Heissel S, Plaza-Jennings A, Miglani S, Asgharian H, Foo M, Katanski CD, Watkins CP, Pennington ZT, Javidfar B, Espeso-Gil S, Rostandy B, Alwaseem H, Hahn CG, Molina H, Cai DJ, Pan T, Yao WD, Goodarzi H, Haghighi F, Akbarian S | Nature communications | 34389722 | Nat Commun | 2021 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/34389722 |
Aversive experience drives offline ensemble reactivation to link memories across days. | Zaki Y, Pennington ZT, Morales-Rodriguez D, Francisco TR, LaBanca AR, Dong Z, Lamsifer S, Segura SC, Chen HT, Wick ZC, Silva AJ, van der Meer M, Shuman T, Fenton A, Rajan K, Cai DJ | bioRxiv : the preprint server for biology | 36993254 | bioRxiv | 2023 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/36993254 |
ezTrack-A Step-by-Step Guide to Behavior Tracking. | Pennington ZT, Diego KS, Francisco TR, LaBanca AR, Lamsifer SI, Liobimova O, Shuman T, Cai DJ | Current protocols | 34610215 | Curr Protoc | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/34610215 |
The brain in motion: How ensemble fluidity drives memory-updating and flexibility. | Mau W, Hasselmo ME, Cai DJ | eLife | 33372892 | Elife | 2020 Dec 29 | https://www.ncbi.nlm.nih.gov/pubmed/33372892 |
A Double Hit of Social and Economic Stress in Mice Precipitates Changes in Decision-Making Strategies. | Durand-de Cuttoli R, Martínez-Rivera FJ, Li L, Minier-Toribio A, Dong Z, Cai DJ, Russo SJ, Nestler EJ, Sweis BM | Biological psychiatry | 38141911 | Biol Psychiatry | 2024 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/38141911 |
Simultaneous dual-color calcium imaging in freely-behaving mice. | Dong Z, Feng Y, Diego K, Baggetta AM, Sweis BM, Pennington ZT, Lamsifer SI, Zaki Y, Sangiuliano F, Philipsberg PA, Morales-Rodriguez D, Kircher D, Slesinger P, Shuman T, Aharoni D, Cai DJ | bioRxiv : the preprint server for biology | 39005306 | bioRxiv | 2024 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/39005306 |
Memory engram stability and flexibility. | Zaki Y, Cai DJ | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 39300271 | Neuropsychopharmacology | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39300271 |
Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer's disease pathology. | Vetere LM, Galas AM, Vaughan N, Feng Y, Wick ZC, Philipsberg PA, Liobimova O, Fernandez-Ruiz A, Cai DJ, Shuman T | bioRxiv : the preprint server for biology | 39868201 | bioRxiv | 2025 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/39868201 |
Creating Space for Synaptic Formation-A New Role for Microglia in Synaptic Plasticity. | Zaki Y, Cai DJ | Cell | 32707091 | Cell | 2020 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/32707091 |
The role of intrinsic excitability in the evolution of memory: Significance in memory allocation, consolidation, and updating. | Chen L, Cummings KA, Mau W, Zaki Y, Dong Z, Rabinowitz S, Clem RL, Shuman T, Cai DJ | Neurobiology of learning and memory | 32512183 | Neurobiol Learn Mem | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32512183 |
ezTrack: An open-source video analysis pipeline for the investigation of animal behavior. | Pennington ZT, Dong Z, Feng Y, Vetere LM, Page-Harley L, Shuman T, Cai DJ | Scientific reports | 31882950 | Sci Rep | 2019 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/31882950 |
Dynamic and heterogeneous neural ensembles contribute to a memory engram. | Sweis BM, Mau W, Rabinowitz S, Cai DJ | Current opinion in neurobiology | 33388602 | Curr Opin Neurobiol | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33388602 |
Minian, an open-source miniscope analysis pipeline. | Dong Z, Mau W, Feng Y, Pennington ZT, Chen L, Zaki Y, Rajan K, Shuman T, Aharoni D, Cai DJ | eLife | 35642786 | Elife | 2022 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/35642786 |
Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior. | Pennington ZT, LaBanca AR, Sompolpong P, Abdel-Raheim SD, Ko B, Christenson Wick Z, Feng Y, Dong Z, Francisco TR, Bacon ME, Chen L, Fulton SL, Maze I, Shuman T, Cai DJ | bioRxiv : the preprint server for biology | 36945605 | bioRxiv | 2024 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/36945605 |
Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy. | Feng Y, Diego KS, Dong Z, Wick ZC, Page-Harley L, Page-Harley V, Schnipper J, Lamsifer SI, Pennington ZT, Vetere LM, Philipsberg PA, Soler I, Jurkowski A, Rosado CJ, Khan NN, Cai DJ, Shuman T | bioRxiv : the preprint server for biology | 38559224 | bioRxiv | 2024 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/38559224 |
Progressive Excitability Changes in the Medial Entorhinal Cortex in the 3xTg Mouse Model of Alzheimer's Disease Pathology. | Chen L, Christenson Wick Z, Vetere LM, Vaughan N, Jurkowski A, Galas A, Diego KS, Philipsberg PA, Soler I, Feng Y, Cai DJ, Shuman T | The Journal of neuroscience : the official journal of the Society for Neuroscience | 37714705 | J Neurosci | 2023 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/37714705 |
A distinct signaling pathway in parvalbumin-positive interneurons controls flexible memory updating. | Cai DJ, Shuman T | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 35236915 | Neuropsychopharmacology | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35236915 |
Ensemble-specific deficit in neuronal intrinsic excitability in aged mice. | Chen L, Francisco TR, Baggetta AM, Zaki Y, Ramirez S, Clem RL, Shuman T, Cai DJ | Neurobiology of aging | 36652783 | Neurobiol Aging | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36652783 |
Drift of neural ensembles driven by slow fluctuations of intrinsic excitability. | Delamare G, Zaki Y, Cai DJ, Clopath C | eLife | 38712831 | Elife | 2024 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/38712831 |
Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior. | Pennington ZT, LaBanca AR, Sompolpong P, Abdel-Raheim SD, Ko B, Christenson Wick Z, Feng Y, Dong Z, Francisco TR, Bacon ME, Chen L, Fulton SL, Maze I, Shuman T, Cai DJ | Cell reports | 39427320 | Cell Rep | 2024 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/39427320 |
Offline ensemble co-reactivation links memories across days. | Zaki Y, Pennington ZT, Morales-Rodriguez D, Bacon ME, Ko B, Francisco TR, LaBanca AR, Sompolpong P, Dong Z, Lamsifer S, Chen HT, Carrillo Segura S, Christenson Wick Z, Silva AJ, Rajan K, van der Meer M, Fenton A, Shuman T, Cai DJ | Nature | 39506117 | Nature | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39506117 |
Propranolol Inhibits Reactivation of Fear Memory. | Pennington ZT, Cai DJ | Biological psychiatry | 34082886 | Biol Psychiatry | 2021 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/34082886 |
Breakdown of spatial coding and interneuron synchronization in epileptic mice. | Shuman T, Aharoni D, Cai DJ, Lee CR, Chavlis S, Page-Harley L, Vetere LM, Feng Y, Yang CY, Mollinedo-Gajate I, Chen L, Pennington ZT, Taxidis J, Flores SE, Cheng K, Javaherian M, Kaba CC, Rao N, La-Vu M, Pandi I, Shtrahman M, Bakhurin KI, Masmanidis SC, Khakh BS, Poirazi P, Silva AJ, Golshani P | Nature neuroscience | 31907437 | Nat Neurosci | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31907437 |
Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer's disease pathology. | Chen L, Wick ZC, Vetere LM, Vaughan N, Jurkowski A, Galas A, Diego KS, Philipsberg P, Cai DJ, Shuman T | bioRxiv : the preprint server for biology | 37398359 | bioRxiv | 2023 May 30 | https://www.ncbi.nlm.nih.gov/pubmed/37398359 |
Chemotagging: a chemogenetic approach for identifying cell types with in vivo calcium imaging. | Ko B, Bacon ME, Zaki Y, Cai DJ | bioRxiv : the preprint server for biology | 39651295 | bioRxiv | 2024 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/39651295 |
An anterior hypothalamic circuit gates stress vulnerability. | Pennington ZT, LaBanca AR, Abdel-Raheim SD, Bacon ME, Mahmoud AN, Sompolpong P, Baggetta AM, Zaki Y, Ko B, Dong Z, Smith AC, Kenny PJ, Cai DJ | bioRxiv : the preprint server for biology | 39554090 | bioRxiv | 2024 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/39554090 |
Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy. | Feng Y, Diego KS, Dong Z, Christenson Wick Z, Page-Harley L, Page-Harley V, Schnipper J, Lamsifer SI, Pennington ZT, Vetere LM, Philipsberg PA, Soler I, Jurkowski A, Rosado CJ, Khan NN, Cai DJ, Shuman T | Cell reports | 39847482 | Cell Rep | 2025 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/39847482 |
Enhancing Precision and Efficiency of Cas9-Mediated Knockin Through Combinatorial Fusions of DNA Repair Proteins. | Richardson RR, Steyert M, Khim SN, Crutcher GW, Brandenburg C, Robertson CD, Romanowski AJ, Inen J, Altas B, Poulopoulos A | The CRISPR journal | 37713292 | CRISPR J | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37713292 |
Rapid modeling of an ultra-rare epilepsy variant in wild-type mice by in utero prime editing. | Robertson CD, Davis P, Richardson RR, Iffland PH 2nd, Vieira DCO, Steyert M, McKeon PN, Romanowski AJ, Crutcher G, Jašarević E, Wolff SBE, Mathur BN, Crino PB, Bale TL, Dick IE, Poulopoulos A | bioRxiv : the preprint server for biology | 38106154 | bioRxiv | 2023 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/38106154 |
Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory Versus Inhibitory Synapses. | Altas B, Tuffy LP, Patrizi A, Dimova K, Soykan T, Brandenburg C, Romanowski AJ, Whitten JR, Robertson CD, Khim SN, Crutcher GW, Ambrozkiewicz MC, Yagensky O, Krueger-Burg D, Hammer M, Hsiao HH, Laskowski PR, Dyck L, Puche AC, Sassoè-Pognetto M, Chua JJE, Urlaub H, Jahn O, Brose N, Poulopoulos A | Biological psychiatry | 38154503 | Biol Psychiatry | 2024 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/38154503 |
Neuronal mTOR Outposts: Implications for Translation, Signaling, and Plasticity. | Altas B, Romanowski AJ, Bunce GW, Poulopoulos A | Frontiers in cellular neuroscience | 35465614 | Front Cell Neurosci | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35465614 |
India ink to 3D imaging: The legacy of Dr. Deepak "Dee" N. Pandya and his influence on generations of neuroanatomists. | Blatt GJ, Brandenburg C, Poulopoulos A | The Journal of comparative neurology | 37916788 | J Comp Neurol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37916788 |
Symmetry in levels of axon-axon homophilic adhesion establishes topography in the corpus callosum and development of connectivity between brain hemispheres. | Poulopoulos A, Davis P, Brandenburg C, Itoh Y, Galazo MJ, Greig LC, Romanowski AJ, Budnik B, Macklis JD | bioRxiv : the preprint server for biology | 38585721 | bioRxiv | 2024 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/38585721 |
NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination and seizure threshold. | Iffland PH, Everett ME, Cobb-Pitstick KM, Bowser LE, Barnes AE, Babus JK, Romanowski AJ, Baybis M, Elziny S, Puffenberger EG, Gonzaga-Jauregui C, Poulopoulos A, Carson VJ, Crino PB | Brain : a journal of neurology | 35136953 | Brain | 2022 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/35136953 |
The brain's dark transcriptome: Sequencing RNA in distal compartments of neurons and glia. | Ament SA, Poulopoulos A | Current opinion in neurobiology | 37196598 | Curr Opin Neurobiol | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37196598 |
Dysfunctional Cortical Gradient Topography in Treatment-Resistant Major Depressive Disorder. | Pasquini L, Fryer SL, Eisendrath SJ, Segal ZV, Lee AJ, Brown JA, Saggar M, Mathalon DH | Biological psychiatry. Cognitive neuroscience and neuroimaging | 36754677 | Biol Psychiatry Cogn Neurosci Neuroimaging | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36754677 |
Development of top-down cortical propagations in youth. | Pines A, Keller AS, Larsen B, Bertolero M, Ashourvan A, Bassett DS, Cieslak M, Covitz S, Fan Y, Feczko E, Houghton A, Rueter AR, Saggar M, Shafiei G, Tapera TM, Vogel J, Weinstein SM, Shinohara RT, Williams LM, Fair DA, Satterthwaite TD | Neuron | 36803653 | Neuron | 2023 Apr 19 | https://www.ncbi.nlm.nih.gov/pubmed/36803653 |
Temporal Mapper: Transition networks in simulated and real neural dynamics. | Zhang M, Chowdhury S, Saggar M | Network neuroscience (Cambridge, Mass.) | 37397880 | Netw Neurosci | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37397880 |
Neural resources shift under Methylphenidate: A computational approach to examine anxiety-cognition interplay. | Saggar M, Bruno J, Gaillard C, Claudino L, Ernst M | NeuroImage | 36273770 | Neuroimage | 2022 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/36273770 |
Precision dynamical mapping using topological data analysis reveals a hub-like transition state at rest. | Saggar M, Shine JM, Liégeois R, Dosenbach NUF, Fair D | Nature communications | 35970984 | Nat Commun | 2022 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/35970984 |
Cross-attractor modeling of resting-state functional connectivity in psychiatric disorders. | Sun Y, Zhang M, Saggar M | NeuroImage | 37579998 | Neuroimage | 2023 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/37579998 |
Generating dynamical neuroimaging spatiotemporal representations (DyNeuSR) using topological data analysis. | Geniesse C, Sporns O, Petri G, Saggar M | Network neuroscience (Cambridge, Mass.) | 31410378 | Netw Neurosci | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31410378 |
Pushing the Boundaries of Psychiatric Neuroimaging to Ground Diagnosis in Biology. | Saggar M, Uddin LQ | eNeuro | 31685674 | eNeuro | 2019 Nov/Dec | https://www.ncbi.nlm.nih.gov/pubmed/31685674 |
Deconstructing the Mapper algorithm to extract richer topological and temporal features from functional neuroimaging data. | Haşegan D, Geniesse C, Chowdhury S, Saggar M | bioRxiv : the preprint server for biology | 37904918 | bioRxiv | 2023 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/37904918 |
Thalamocortical connectivity is associated with autism symptoms in high-functioning adults with autism and typically developing adults. | Ayub R, Sun KL, Flores RE, Lam VT, Jo B, Saggar M, Fung LK | Translational psychiatry | 33536431 | Transl Psychiatry | 2021 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/33536431 |
Increased anti-correlation between the left dorsolateral prefrontal cortex and the default mode network following Stanford Neuromodulation Therapy (SNT): analysis of a double-blinded, randomized, sham-controlled trial. | Gajawelli N, Geoly AD, Batail JM, Xiao X, Maron-Katz A, Cole E, Azeez A, Kratter IH, Saggar M, Williams NR | Npj mental health research | 38971869 | Npj Ment Health Res | 2024 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/38971869 |
Network effects of Stanford Neuromodulation Therapy (SNT) in treatment-resistant major depressive disorder: a randomized, controlled trial. | Batail JM, Xiao X, Azeez A, Tischler C, Kratter IH, Bishop JH, Saggar M, Williams NR | Translational psychiatry | 37400432 | Transl Psychiatry | 2023 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/37400432 |
Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice. | Rosenberg AM, Saggar M, Monzel AS, Devine J, Rogu P, Limoges A, Junker A, Sandi C, Mosharov EV, Dumitriu D, Anacker C, Picard M | Nature communications | 37563104 | Nat Commun | 2023 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/37563104 |
Cross-attractor repertoire provides new perspective on structure-function relationship in the brain. | Zhang M, Sun Y, Saggar M | NeuroImage | 35732244 | Neuroimage | 2022 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/35732244 |
NeuMapper: A scalable computational framework for multiscale exploration of the brain's dynamical organization. | Geniesse C, Chowdhury S, Saggar M | Network neuroscience (Cambridge, Mass.) | 35733428 | Netw Neurosci | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35733428 |
Spontaneous and deliberate modes of creativity: Multitask eigen-connectivity analysis captures latent cognitive modes during creative thinking. | Xie H, Beaty RE, Jahanikia S, Geniesse C, Sonalkar NS, Saggar M | NeuroImage | 34469816 | Neuroimage | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34469816 |
Altered canonical and striatal-frontal resting state functional connectivity in children with pathogenic variants in the Ras/mitogen-activated protein kinase pathway. | Bruno JL, Shrestha SB, Reiss AL, Saggar M, Green T | Molecular psychiatry | 35087195 | Mol Psychiatry | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35087195 |
Densely sampled stimulus-response map of human cortex with single pulse TMS-EEG and its relation to whole brain neuroimaging measures. | Sun Y, Lucas MV, Cline CC, Menezes MC, Kim S, Badami FS, Narayan M, Wu W, Daskalakis ZJ, Etkin A, Saggar M | bioRxiv : the preprint server for biology | 38948696 | bioRxiv | 2024 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/38948696 |
Brief intensive social gaze training reorganizes functional brain connectivity in boys with fragile X syndrome. | Saggar M, Bruno JL, Hall SS | Cerebral cortex (New York, N.Y. : 1991) | 36376964 | Cereb Cortex | 2023 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/36376964 |
Sex differences in the reward value of familiar mates in prairie voles. | Vahaba DM, Halstead ER, Donaldson ZR, Ahern TH, Beery AK | Genes, brain, and behavior | 35044087 | Genes Brain Behav | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35044087 |
Emergent intra-pair sex differences and organized behavior in pair bonded prairie voles (Microtus ochrogaster). | Brusman LE, Protter DSW, Fultz AC, Paulson MU, Chapel GD, Elges IO, Cameron RT, Beery AK, Donaldson ZR | Genes, brain, and behavior | 35044090 | Genes Brain Behav | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35044090 |
Prairie vole pair bonding and plasticity of the social brain. | Hiura LC, Donaldson ZR | Trends in neurosciences | 36369029 | Trends Neurosci | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36369029 |
Nucleus accumbens dopamine release reflects the selective nature of pair bonds. | Pierce AF, Protter DSW, Watanabe YL, Chapel GD, Cameron RT, Donaldson ZR | Current biology : CB | 38218185 | Curr Biol | 2024 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/38218185 |
Exposure to novel females increases fecundity in adult male prairie voles. | Hurd JA, Watanabe YL, Toben GJ, Ford AK, Miller CA, Sergott CE, Kelley D, Donaldson ZR, McCullagh EA | bioRxiv : the preprint server for biology | 39763992 | bioRxiv | 2024 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/39763992 |
PhAT: A flexible open-source GUI-driven toolkit for photometry analysis. | Murphy KZ, Haile E, McTigue A, Pierce AF, Donaldson ZR | bioRxiv : the preprint server for biology | 36993180 | bioRxiv | 2023 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/36993180 |
Neurobiology and treatment advances for prolonged grief disorder. | Donaldson ZR, Shear MK | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 37479860 | Neuropsychopharmacology | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/37479860 |
Prolonged partner separation erodes nucleus accumbens transcriptional signatures of pair bonding in male prairie voles. | Sadino JM, Bradeen XG, Kelly CJ, Brusman LE, Walker DM, Donaldson ZR | eLife | 36852906 | Elife | 2023 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/36852906 |
Wireless multilateral devices for optogenetic studies of individual and social behaviors. | Yang Y, Wu M, Vázquez-Guardado A, Wegener AJ, Grajales-Reyes JG, Deng Y, Wang T, Avila R, Moreno JA, Minkowicz S, Dumrongprechachan V, Lee J, Zhang S, Legaria AA, Ma Y, Mehta S, Franklin D, Hartman L, Bai W, Han M, Zhao H, Lu W, Yu Y, Sheng X, Banks A, Yu X, Donaldson ZR, Gereau RW 4th, Good CH, Xie Z, Huang Y, Kozorovitskiy Y, Rogers JA | Nature neuroscience | 33972800 | Nat Neurosci | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33972800 |
How prior pair-bonding experience affects future bonding behavior in monogamous prairie voles. | Harbert KJ, Pellegrini M, Gordon KM, Donaldson ZR | Hormones and behavior | 32910950 | Horm Behav | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32910950 |
A neuronal signature for monogamous reunion. | Scribner JL, Vance EA, Protter DSW, Sheeran WM, Saslow E, Cameron RT, Klein EM, Jimenez JC, Kheirbek MA, Donaldson ZR | Proceedings of the National Academy of Sciences of the United States of America | 32381740 | Proc Natl Acad Sci U S A | 2020 May 19 | https://www.ncbi.nlm.nih.gov/pubmed/32381740 |
Prairie voles as a model for adaptive reward remodeling following loss of a bonded partner. | Sadino JM, Donaldson ZR | Annals of the New York Academy of Sciences | 38594916 | Ann N Y Acad Sci | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38594916 |
PhAT: A Flexible Open-Source GUI-Driven Toolkit for Photometry Analysis. | Murphy KZ, Haile ED, McTigue AD, Pierce AF, Donaldson ZR | Current protocols | 37184156 | Curr Protoc | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37184156 |
Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering. | Chen Y, Jang H, Spratt PWE, Kosar S, Taylor DE, Essner RA, Bai L, Leib DE, Kuo TW, Lin YC, Patel M, Subkhangulova A, Kato S, Feinberg EH, Bender KJ, Knight ZA, Garrison JL | Neuron | 32574560 | Neuron | 2020 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/32574560 |
Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. | Cheung V, Chung P, Bjorni M, Shvareva VA, Lopez YC, Feinberg EH | Cell reports | 34936877 | Cell Rep | 2021 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/34936877 |
Hindbrain modules differentially transform activity of single collicular neurons to coordinate movements. | Zahler SH, Taylor DE, Wright BS, Wong JY, Shvareva VA, Park YA, Feinberg EH | Cell | 37343561 | Cell | 2023 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/37343561 |
Transcriptional profiling of mouse projection neurons with VECTORseq. | Cheung V, Chung P, Feinberg EH | STAR protocols | 36035788 | STAR Protoc | 2022 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/36035788 |
Superior colliculus drives stimulus-evoked directionally biased saccades and attempted head movements in head-fixed mice. | Zahler SH, Taylor DE, Wong JY, Adams JM, Feinberg EH | eLife | 34970968 | Elife | 2021 Dec 31 | https://www.ncbi.nlm.nih.gov/pubmed/34970968 |
DART.2: bidirectional synaptic pharmacology with thousandfold cellular specificity. | Shields BC, Yan H, Lim SSX, Burwell SCV, Cammarata CM, Fleming EA, Yousefzadeh SA, Goldenshtein VZ, Kahuno EW, Vagadia PP, Loughran MH, Zhiquan L, McDonnell ME, Scalabrino ML, Thapa M, Hawley TM, Field GD, Hull C, Schiltz GE, Glickfeld LL, Reitz AB, Tadross MR | Nature methods | 38877316 | Nat Methods | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38877316 |
Noradrenergic Signaling Disengages Feedforward Transmission in the Nucleus Accumbens Shell. | Manz KM, Coleman BC, Grueter CA, Shields BC, Tadross MR, Grueter BA | The Journal of neuroscience : the official journal of the Society for Neuroscience | 33737458 | J Neurosci | 2021 Apr 28 | https://www.ncbi.nlm.nih.gov/pubmed/33737458 |
Acute restraint stress redirects prefrontal cortex circuit function through mGlu(5) receptor plasticity on somatostatin-expressing interneurons. | Joffe ME, Maksymetz J, Luschinger JR, Dogra S, Ferranti AS, Luessen DJ, Gallinger IM, Xiang Z, Branthwaite H, Melugin PR, Williford KM, Centanni SW, Shields BC, Lindsley CW, Calipari ES, Siciliano CA, Niswender CM, Tadross MR, Winder DG, Conn PJ | Neuron | 35045338 | Neuron | 2022 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/35045338 |
Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations. | Fleming EA, Field GD, Tadross MR, Hull C | Nature neuroscience | 38321293 | Nat Neurosci | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38321293 |
Natural phasic inhibition of dopamine neurons signals cognitive rigidity. | Burwell SCV, Yan H, Lim SSX, Shields BC, Tadross MR | bioRxiv : the preprint server for biology | 38766037 | bioRxiv | 2024 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/38766037 |
An open-source transparent microelectrode array. | Weaver IA, Li AW, Shields BC, Tadross MR | Journal of neural engineering | 35349992 | J Neural Eng | 2022 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/35349992 |
Identification of Structural Variation in Chimpanzees Using Optical Mapping and Nanopore Sequencing. | Soto DC, Shew C, Mastoras M, Schmidt JM, Sahasrabudhe R, Kaya G, Andrés AM, Dennis MY | Genes | 32143403 | Genes (Basel) | 2020 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/32143403 |
Evaluation of CRISPR gene-editing tools in zebrafish. | Uribe-Salazar JM, Kaya G, Sekar A, Weyenberg K, Ingamells C, Dennis MY | BMC genomics | 34986794 | BMC Genomics | 2022 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/34986794 |
A complete reference genome improves analysis of human genetic variation. | Aganezov S, Yan SM, Soto DC, Kirsche M, Zarate S, Avdeyev P, Taylor DJ, Shafin K, Shumate A, Xiao C, Wagner J, McDaniel J, Olson ND, Sauria MEG, Vollger MR, Rhie A, Meredith M, Martin S, Lee J, Koren S, Rosenfeld JA, Paten B, Layer R, Chin CS, Sedlazeck FJ, Hansen NF, Miller DE, Phillippy AM, Miga KH, McCoy RC, Dennis MY, Zook JM, Schatz MC | Science (New York, N.Y.) | 35357935 | Science | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35357935 |
Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes. | Shew CJ, Carmona-Mora P, Soto DC, Mastoras M, Roberts E, Rosas J, Jagannathan D, Kaya G, O'Geen H, Dennis MY | Molecular biology and evolution | 34009325 | Mol Biol Evol | 2021 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/34009325 |
LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons. | Libé-Philippot B, Lejeune A, Wierda K, Louros N, Erkol E, Vlaeminck I, Beckers S, Gaspariunaite V, Bilheu A, Konstantoulea K, Nyitrai H, De Vleeschouwer M, Vennekens KM, Vidal N, Bird TW, Soto DC, Jaspers T, Dewilde M, Dennis MY, Rousseau F, Comoletti D, Schymkowitz J, Theys T, de Wit J, Vanderhaeghen P | Cell | 38134874 | Cell | 2023 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/38134874 |
Local genetic adaptation to habitat in wild chimpanzees. | Ostridge HJ, Fontsere C, Lizano E, Soto DC, Schmidt JM, Saxena V, Alvarez-Estape M, Barratt CD, Gratton P, Bocksberger G, Lester JD, Dieguez P, Agbor A, Angedakin S, Assumang AK, Bailey E, Barubiyo D, Bessone M, Brazzola G, Chancellor R, Cohen H, Coupland C, Danquah E, Deschner T, Dotras L, Dupain J, Egbe VE, Granjon AC, Head J, Hedwig D, Hermans V, Hernandez-Aguilar RA, Jeffery KJ, Jones S, Junker J, Kadam P, Kaiser M, Kalan AK, Kambere M, Kienast I, Kujirakwinja D, Langergraber KE, Lapuente J, Larson B, Laudisoit A, Lee KC, Llana M, Maretti G, Martín R, Meier A, Morgan D, Neil E, Nicholl S, Nixon S, Normand E, Orbell C, Ormsby LJ, Orume R, Pacheco L, Preece J, Regnaut S, Robbins MM, Rundus A, Sanz C, Sciaky L, Sommer V, Stewart FA, Tagg N, Tédonzong LR, van Schijndel J, Vendras E, Wessling EG, Willie J, Wittig RM, Yuh YG, Yurkiw K, Vigilant L, Piel A, Boesch C, Kühl HS, Dennis MY, Marques-Bonet T, Arandjelovic M, Andrés AM | bioRxiv : the preprint server for biology | 39026872 | bioRxiv | 2024 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/39026872 |
Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development. | Uribe-Salazar JM, Kaya G, Weyenberg K, Radke B, Hino K, Soto DC, Shiu JL, Zhang W, Ingamells C, Haghani NK, Xu E, Rosas J, Simó S, Miesfeld J, Glaser T, Baraban SC, Jao LE, Dennis MY | bioRxiv : the preprint server for biology | 39314374 | bioRxiv | 2024 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/39314374 |
Complete genomic and epigenetic maps of human centromeres. | Altemose N, Logsdon GA, Bzikadze AV, Sidhwani P, Langley SA, Caldas GV, Hoyt SJ, Uralsky L, Ryabov FD, Shew CJ, Sauria MEG, Borchers M, Gershman A, Mikheenko A, Shepelev VA, Dvorkina T, Kunyavskaya O, Vollger MR, Rhie A, McCartney AM, Asri M, Lorig-Roach R, Shafin K, Lucas JK, Aganezov S, Olson D, de Lima LG, Potapova T, Hartley GA, Haukness M, Kerpedjiev P, Gusev F, Tigyi K, Brooks S, Young A, Nurk S, Koren S, Salama SR, Paten B, Rogaev EI, Streets A, Karpen GH, Dernburg AF, Sullivan BA, Straight AF, Wheeler TJ, Gerton JL, Eichler EE, Phillippy AM, Timp W, Dennis MY, O'Neill RJ, Zook JM, Schatz MC, Pevzner PA, Diekhans M, Langley CH, Alexandrov IA, Miga KH | Science (New York, N.Y.) | 35357911 | Science | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35357911 |
Telomere-to-telomere assembly of a complete human X chromosome. | Miga KH, Koren S, Rhie A, Vollger MR, Gershman A, Bzikadze A, Brooks S, Howe E, Porubsky D, Logsdon GA, Schneider VA, Potapova T, Wood J, Chow W, Armstrong J, Fredrickson J, Pak E, Tigyi K, Kremitzki M, Markovic C, Maduro V, Dutra A, Bouffard GG, Chang AM, Hansen NF, Wilfert AB, Thibaud-Nissen F, Schmitt AD, Belton JM, Selvaraj S, Dennis MY, Soto DC, Sahasrabudhe R, Kaya G, Quick J, Loman NJ, Holmes N, Loose M, Surti U, Risques RA, Graves Lindsay TA, Fulton R, Hall I, Paten B, Howe K, Timp W, Young A, Mullikin JC, Pevzner PA, Gerton JL, Sullivan BA, Eichler EE, Phillippy AM | Nature | 32663838 | Nature | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32663838 |
Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. | Zhu Y, Gomez JA, Laufer BI, Mordaunt CE, Mouat JS, Soto DC, Dennis MY, Benke KS, Bakulski KM, Dou J, Marathe R, Jianu JM, Williams LA, Gutierrez Fugón OJ, Walker CK, Ozonoff S, Daniels J, Grosvenor LP, Volk HE, Feinberg JI, Fallin MD, Hertz-Picciotto I, Schmidt RJ, Yasui DH, LaSalle JM | Genome biology | 35168652 | Genome Biol | 2022 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/35168652 |
FixItFelix: improving genomic analysis by fixing reference errors. | Behera S, LeFaive J, Orchard P, Mahmoud M, Paulin LF, Farek J, Soto DC, Parker SCJ, Smith AV, Dennis MY, Zook JM, Sedlazeck FJ | Genome biology | 36810122 | Genome Biol | 2023 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/36810122 |
Assessment of Autism Zebrafish Mutant Models Using a High-Throughput Larval Phenotyping Platform. | Colón-Rodríguez A, Uribe-Salazar JM, Weyenberg KB, Sriram A, Quezada A, Kaya G, Jao E, Radke B, Lein PJ, Dennis MY | Frontiers in cell and developmental biology | 33330465 | Front Cell Dev Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33330465 |
The complete sequence of a human genome. | Nurk S, Koren S, Rhie A, Rautiainen M, Bzikadze AV, Mikheenko A, Vollger MR, Altemose N, Uralsky L, Gershman A, Aganezov S, Hoyt SJ, Diekhans M, Logsdon GA, Alonge M, Antonarakis SE, Borchers M, Bouffard GG, Brooks SY, Caldas GV, Chen NC, Cheng H, Chin CS, Chow W, de Lima LG, Dishuck PC, Durbin R, Dvorkina T, Fiddes IT, Formenti G, Fulton RS, Fungtammasan A, Garrison E, Grady PGS, Graves-Lindsay TA, Hall IM, Hansen NF, Hartley GA, Haukness M, Howe K, Hunkapiller MW, Jain C, Jain M, Jarvis ED, Kerpedjiev P, Kirsche M, Kolmogorov M, Korlach J, Kremitzki M, Li H, Maduro VV, Marschall T, McCartney AM, McDaniel J, Miller DE, Mullikin JC, Myers EW, Olson ND, Paten B, Peluso P, Pevzner PA, Porubsky D, Potapova T, Rogaev EI, Rosenfeld JA, Salzberg SL, Schneider VA, Sedlazeck FJ, Shafin K, Shew CJ, Shumate A, Sims Y, Smit AFA, Soto DC, Sović I, Storer JM, Streets A, Sullivan BA, Thibaud-Nissen F, Torrance J, Wagner J, Walenz BP, Wenger A, Wood JMD, Xiao C, Yan SM, Young AC, Zarate S, Surti U, McCoy RC, Dennis MY, Alexandrov IA, Gerton JL, O'Neill RJ, Timp W, Zook JM, Schatz MC, Eichler EE, Miga KH, Phillippy AM | Science (New York, N.Y.) | 35357919 | Science | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35357919 |
RapID Cell Counter: Semi-Automated and Mid-Throughput Estimation of Cell Density within Diverse Cortical Layers. | Sekar A, Sanches TM, Hino K, Kumar M, Wang J, Ha E, Durbin-Johnson B, Simó S, Dennis MY | eNeuro | 34725102 | eNeuro | 2021 Nov-Dec | https://www.ncbi.nlm.nih.gov/pubmed/34725102 |
Genomic structural variation: A complex but important driver of human evolution. | Soto DC, Uribe-Salazar JM, Shew CJ, Sekar A, McGinty SP, Dennis MY | American journal of biological anthropology | 36794631 | Am J Biol Anthropol | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/36794631 |
m(6)A-mRNA Reader YTHDF2 Identified as a Potential Risk Gene in Autism With Disproportionate Megalencephaly. | Nishizaki SS, Haghani NK, La GN, Mariano NAF, Uribe-Salazar JM, Kaya G, Regester M, Andrews DS, Nordahl CW, Amaral DG, Dennis MY | Autism research : official journal of the International Society for Autism Research | 39887636 | Autism Res | 2025 Jan 30 | https://www.ncbi.nlm.nih.gov/pubmed/39887636 |
Cell arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilms. | Dayton H, Kiss J, Wei M, Chauhan S, LaMarre E, Cornell WC, Morgan CJ, Janakiraman A, Min W, Tomer R, Price-Whelan A, Nirody JA, Dietrich LEP | bioRxiv : the preprint server for biology | 37645902 | bioRxiv | 2023 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/37645902 |
Focused ultrasound-mediated brain genome editing. | Lao YH, Ji R, Zhou JK, Snow KJ, Kwon N, Saville E, He S, Chauhan S, Chi CW, Datta MS, Zhang H, Quek CH, Cai SS, Li M, Gaitan Y, Bechtel L, Wu SY, Lutz CM, Tomer R, Murray SA, Chavez A, Konofagou EE, Leong KW | Proceedings of the National Academy of Sciences of the United States of America | 37579143 | Proc Natl Acad Sci U S A | 2023 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/37579143 |
Cortical overgrowth in a preclinical forebrain organoid model of CNTNAP2-associated autism spectrum disorder. | de Jong JO, Llapashtica C, Genestine M, Strauss K, Provenzano F, Sun Y, Zhu H, Cortese GP, Brundu F, Brigatti KW, Corneo B, Migliori B, Tomer R, Kushner SA, Kellendonk C, Javitch JA, Xu B, Markx S | Nature communications | 34471112 | Nat Commun | 2021 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/34471112 |
Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples. | Chen Y, Chauhan S, Gong C, Dayton H, Xu C, De La Cruz ED, Tsai YW, Datta MS, Rosoklija GB, Dwork AJ, Mann JJ, Boldrini M, Leong KW, Dietrich LEP, Tomer R | Nature biomedical engineering | 39209948 | Nat Biomed Eng | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39209948 |
A miniaturized multi-clamp CMOS amplifier for intracellular neural recording. | Shekar S, Jayant K, Rabadan MA, Tomer R, Yuste R, Shepard KL | Nature electronics | 31850397 | Nat Electron | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31850397 |
Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system. | Datta MS, Chen Y, Chauhan S, Zhang J, De La Cruz ED, Gong C, Tomer R | bioRxiv : the preprint server for biology | 37090584 | bioRxiv | 2023 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/37090584 |
A Microfluidic Dual-Aptamer Sandwich Assay for Rapid and Cost-Effective Detection of Recombinant Proteins. | Wen K, Chen Y, Meng X, Botros S, Dai W, Stojanovic MN, Tomer R, Lin Q | Microchemical journal : devoted to the application of microtechniques in all branches of science | 36992861 | Microchem J | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/36992861 |
Scalable projected Light Sheet Microscopy for high-resolution imaging of living and cleared samples. | Chen Y, Chauhan S, Gong C, Dayton H, Xu C, De La Cruz ED, Datta MS, Leong KW, Dietrich LEP, Tomer R | bioRxiv : the preprint server for biology | 37333196 | bioRxiv | 2023 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/37333196 |
Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system. | Datta MS, Chen Y, Chauhan S, Zhang J, De La Cruz ED, Gong C, Tomer R | Cell reports | 38052211 | Cell Rep | 2023 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/38052211 |
Cellular arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilms. | Dayton H, Kiss J, Wei M, Chauhan S, LaMarre E, Cornell WC, Morgan CJ, Janakiraman A, Min W, Tomer R, Price-Whelan A, Nirody JA, Dietrich LEP | PLoS biology | 38300958 | PLoS Biol | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38300958 |
Light sheet theta microscopy for rapid high-resolution imaging of large biological samples. | Migliori B, Datta MS, Dupre C, Apak MC, Asano S, Gao R, Boyden ES, Hermanson O, Yuste R, Tomer R | BMC biology | 29843722 | BMC Biol | 2018 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/29843722 |
An in vitro model of neuronal ensembles. | Rabadan MA, De La Cruz ED, Rao SB, Chen Y, Gong C, Crabtree G, Xu B, Markx S, Gogos JA, Yuste R, Tomer R | Nature communications | 35680927 | Nat Commun | 2022 Jun 9 | https://www.ncbi.nlm.nih.gov/pubmed/35680927 |
Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution. | Chakraborty T, Driscoll MK, Jeffery E, Murphy MM, Roudot P, Chang BJ, Vora S, Wong WM, Nielson CD, Zhang H, Zhemkov V, Hiremath C, De La Cruz ED, Yi Y, Bezprozvanny I, Zhao H, Tomer R, Heintzmann R, Meeks JP, Marciano DK, Morrison SJ, Danuser G, Dean KM, Fiolka R | Nature methods | 31673159 | Nat Methods | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31673159 |
Focused ultrasound-mediated brain genome editing. | Leong K, Lao YH, Ji R, Zhou J, Snow K, Kwon N, Saville E, He S, Chauhan S, Chi CW, Datta M, Zhang H, Quek CH, Cai S, Li M, Gaitan Y, Bechtel L, Wu SY, Lutz C, Tomer R, Murray S, Chavez A, Konofagou E | Research square | 36712096 | Res Sq | 2023 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/36712096 |
Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes. | Kelley KW, Nakao-Inoue H, Molofsky AV, Oldham MC | Nature neuroscience | 30154505 | Nat Neurosci | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30154505 |
Microglial pattern recognition via IL-33 promotes synaptic refinement in developing corticothalamic circuits in mice. | Han RT, Vainchtein ID, Schlachetzki JCM, Cho FS, Dorman LC, Ahn E, Kim DK, Barron JJ, Nakao-Inoue H, Molofsky AB, Glass CK, Paz JT, Molofsky AV | The Journal of experimental medicine | 36520518 | J Exp Med | 2023 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/36520518 |
Circuit and molecular architecture of a ventral hippocampal network. | Gergues MM, Han KJ, Choi HS, Brown B, Clausing KJ, Turner VS, Vainchtein ID, Molofsky AV, Kheirbek MA | Nature neuroscience | 32929245 | Nat Neurosci | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32929245 |
Dynamism of an Astrocyte In Vivo: Perspectives on Identity and Function. | Poskanzer KE, Molofsky AV | Annual review of physiology | 29166242 | Annu Rev Physiol | 2018 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/29166242 |
Astrocytes and Microglia: In Sickness and in Health. | Vainchtein ID, Molofsky AV | Trends in neurosciences | 32044129 | Trends Neurosci | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32044129 |
Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity. | Nguyen PT, Dorman LC, Pan S, Vainchtein ID, Han RT, Nakao-Inoue H, Taloma SE, Barron JJ, Molofsky AB, Kheirbek MA, Molofsky AV | Cell | 32615087 | Cell | 2020 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/32615087 |
Type I interferon responsive microglia shape cortical development and behavior. | Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Cuevas B, Vainchtein ID, Silva NJ, Xiao Y, Lidsky PV, Wang EY, Taloma SE, Nakao-Inoue H, Schwer B, Andino R, Nowakowski TJ, Molofsky AV | bioRxiv : the preprint server for biology | 35233577 | bioRxiv | 2023 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/35233577 |
Enhancing GAT-3 in thalamic astrocytes promotes resilience to brain injury in rodents. | Cho FS, Vainchtein ID, Voskobiynyk Y, Morningstar AR, Aparicio F, Higashikubo B, Ciesielska A, Broekaart DWM, Anink JJ, van Vliet EA, Yu X, Khakh BS, Aronica E, Molofsky AV, Paz JT | Science translational medicine | 35857628 | Sci Transl Med | 2022 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/35857628 |
Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior. | Szewczyk LM, Lipiec MA, Liszewska E, Meyza K, Urban-Ciecko J, Kondrakiewicz L, Goncerzewicz A, Rafalko K, Krawczyk TG, Bogaj K, Vainchtein ID, Nakao-Inoue H, Puscian A, Knapska E, Sanders SJ, Jan Nowakowski T, Molofsky AV, Wisniewska MB | Molecular psychiatry | 37798419 | Mol Psychiatry | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/37798419 |
Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development. | Vainchtein ID, Chin G, Cho FS, Kelley KW, Miller JG, Chien EC, Liddelow SA, Nguyen PT, Nakao-Inoue H, Dorman LC, Akil O, Joshita S, Barres BA, Paz JT, Molofsky AB, Molofsky AV | Science (New York, N.Y.) | 29420261 | Science | 2018 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/29420261 |
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice. | Kuhn JA, Vainchtein ID, Braz J, Hamel K, Bernstein M, Craik V, Dahlgren MW, Ortiz-Carpena J, Molofsky AB, Molofsky AV, Basbaum AI | eLife | 34652270 | Elife | 2021 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/34652270 |
In situ and transcriptomic identification of microglia in synapse-rich regions of the developing zebrafish brain. | Silva NJ, Dorman LC, Vainchtein ID, Horneck NC, Molofsky AV | Nature communications | 34625548 | Nat Commun | 2021 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/34625548 |
Location, Location, Location: Transcriptional Control of Astrocyte Heterogeneity. | Rosenberg MF, Molofsky AV | Trends in immunology | 32800455 | Trends Immunol | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32800455 |
The immune system and psychiatric disease: a basic science perspective. | Bennett FC, Molofsky AV | Clinical and experimental immunology | 31125426 | Clin Exp Immunol | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31125426 |
Type-I-interferon-responsive microglia shape cortical development and behavior. | Escoubas CC, Dorman LC, Nguyen PT, Lagares-Linares C, Nakajo H, Anderson SR, Barron JJ, Wade SD, Cuevas B, Vainchtein ID, Silva NJ, Guajardo R, Xiao Y, Lidsky PV, Wang EY, Rivera BM, Taloma SE, Kim DK, Kaminskaya E, Nakao-Inoue H, Schwer B, Arnold TD, Molofsky AB, Condello C, Andino R, Nowakowski TJ, Molofsky AV | Cell | 38490196 | Cell | 2024 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/38490196 |
Nonhuman Primate Optogenetics: Recent Advances and Future Directions. | Galvan A, Stauffer WR, Acker L, El-Shamayleh Y, Inoue KI, Ohayon S, Schmid MC | The Journal of neuroscience : the official journal of the Society for Neuroscience | 29118219 | J Neurosci | 2017 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/29118219 |
Reward and value coding by dopamine neurons in non-human primates. | Alikaya A, Rack-Wildner M, Stauffer WR | Journal of neural transmission (Vienna, Austria : 1996) | 29076112 | J Neural Transm (Vienna) | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29076112 |
Dopamine prediction error responses update demand. | Rothenhoefer KM, Stauffer WR | Proceedings of the National Academy of Sciences of the United States of America | 29233946 | Proc Natl Acad Sci U S A | 2017 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/29233946 |
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scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution. | Öztürk BE, Johnson ME, Kleyman M, Turunç S, He J, Jabalameli S, Xi Z, Visel M, Dufour VL, Iwabe S, Pompeo Marinho LFL, Aguirre GD, Sahel JA, Schaffer DV, Pfenning AR, Flannery JG, Beltran WA, Stauffer WR, Byrne LC | eLife | 34664552 | Elife | 2021 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/34664552 |
Computational complexity drives sustained deliberation. | Hong T, Stauffer WR | Nature neuroscience | 37095398 | Nat Neurosci | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37095398 |
Transcriptional and anatomical diversity of medium spiny neurons in the primate striatum. | He J, Kleyman M, Chen J, Alikaya A, Rothenhoefer KM, Ozturk BE, Wirthlin M, Bostan AC, Fish K, Byrne LC, Pfenning AR, Stauffer WR | Current biology : CB | 34727523 | Curr Biol | 2021 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/34727523 |
The biological and behavioral computations that influence dopamine responses. | Stauffer WR | Current opinion in neurobiology | 29505948 | Curr Opin Neurobiol | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29505948 |
YY1 and CTCF orchestrate a 3D chromatin looping switch during early neural lineage commitment. | Beagan JA, Duong MT, Titus KR, Zhou L, Cao Z, Ma J, Lachanski CV, Gillis DR, Phillips-Cremins JE | Genome research | 28536180 | Genome Res | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28536180 |
Dynamic Looping Interactions: Setting the 3D Stage for the Macrophage. | Rege M, Phillips-Cremins JE | Molecular cell | 28938095 | Mol Cell | 2017 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/28938095 |
LADL: light-activated dynamic looping for endogenous gene expression control. | Kim JH, Rege M, Valeri J, Dunagin MC, Metzger A, Titus KR, Gilgenast TG, Gong W, Beagan JA, Raj A, Phillips-Cremins JE | Nature methods | 31235883 | Nat Methods | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31235883 |
Chromatin structure dynamics during the mitosis-to-G1 phase transition. | Zhang H, Emerson DJ, Gilgenast TG, Titus KR, Lan Y, Huang P, Zhang D, Wang H, Keller CA, Giardine B, Hardison RC, Phillips-Cremins JE, Blobel GA | Nature | 31776509 | Nature | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31776509 |
Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression. | Beagan JA, Pastuzyn ED, Fernandez LR, Guo MH, Feng K, Titus KR, Chandrashekar H, Shepherd JD, Phillips-Cremins JE | Nature neuroscience | 32451484 | Nat Neurosci | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32451484 |
CRISPR/Cas9 genome editing throws descriptive 3-D genome folding studies for a loop. | Beagan JA, Phillips-Cremins JE | Wiley interdisciplinary reviews. Systems biology and medicine | 27265842 | Wiley Interdiscip Rev Syst Biol Med | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27265842 |
3DeFDR: statistical methods for identifying cell type-specific looping interactions in 5C and Hi-C data. | Fernandez LR, Gilgenast TG, Phillips-Cremins JE | Genome biology | 32859248 | Genome Biol | 2020 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/32859248 |
Systematic Evaluation of Statistical Methods for Identifying Looping Interactions in 5C Data. | Gilgenast TG, Phillips-Cremins JE | Cell systems | 30904376 | Cell Syst | 2019 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/30904376 |
A subset of topologically associating domains fold into mesoscale core-periphery networks. | Huang H, Chen ST, Titus KR, Emerson DJ, Bassett DS, Phillips-Cremins JE | Scientific reports | 31266973 | Sci Rep | 2019 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/31266973 |
5C-ID: Increased resolution Chromosome-Conformation-Capture-Carbon-Copy with in situ 3C and double alternating primer design. | Kim JH, Titus KR, Gong W, Beagan JA, Cao Z, Phillips-Cremins JE | Methods (San Diego, Calif.) | 29772275 | Methods | 2018 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/29772275 |
Disease-Associated Short Tandem Repeats Co-localize with Chromatin Domain Boundaries. | Sun JH, Zhou L, Emerson DJ, Phyo SA, Titus KR, Gong W, Gilgenast TG, Beagan JA, Davidson BL, Tassone F, Phillips-Cremins JE | Cell | 30173918 | Cell | 2018 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/30173918 |
Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming. | Beagan JA, Gilgenast TG, Kim J, Plona Z, Norton HK, Hu G, Hsu SC, Shields EJ, Lyu X, Apostolou E, Hochedlinger K, Corces VG, Dekker J, Phillips-Cremins JE | Cell stem cell | 27152443 | Cell Stem Cell | 2016 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/27152443 |
On the existence and functionality of topologically associating domains. | Beagan JA, Phillips-Cremins JE | Nature genetics | 31925403 | Nat Genet | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31925403 |
Detecting hierarchical genome folding with network modularity. | Norton HK, Emerson DJ, Huang H, Kim J, Titus KR, Gu S, Bassett DS, Phillips-Cremins JE | Nature methods | 29334377 | Nat Methods | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29334377 |
Intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode. | Seo C, Guru A, Jin M, Ito B, Sleezer BJ, Ho YY, Wang E, Boada C, Krupa NA, Kullakanda DS, Shen CX, Warden MR | Science (New York, N.Y.) | 30705194 | Science | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30705194 |
Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain. | Wang T, Wu C, Ouzounov DG, Gu W, Xia F, Kim M, Yang X, Warden MR, Xu C | eLife | 31999253 | Elife | 2020 Jan 30 | https://www.ncbi.nlm.nih.gov/pubmed/31999253 |
Tonic activity in lateral habenula neurons acts as a neutral valence brake on reward-seeking behavior. | Post RJ, Bulkin DA, Ebitz RB, Lee V, Han K, Warden MR | Current biology : CB | 36049479 | Curr Biol | 2022 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/36049479 |
Depression: the search for separable behaviors and circuits. | Post RJ, Warden MR | Current opinion in neurobiology | 29529482 | Curr Opin Neurobiol | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29529482 |
Gamma and beta bursts during working memory readout suggest roles in its volitional control. | Lundqvist M, Herman P, Warden MR, Brincat SL, Miller EK | Nature communications | 29374153 | Nat Commun | 2018 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/29374153 |
Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior. | Ferenczi EA, Zalocusky KA, Liston C, Grosenick L, Warden MR, Amatya D, Katovich K, Mehta H, Patenaude B, Ramakrishnan C, Kalanithi P, Etkin A, Knutson B, Glover GH, Deisseroth K | Science (New York, N.Y.) | 26722001 | Science | 2016 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/26722001 |
Infralimbic parvalbumin neural activity facilitates cued threat avoidance. | Ho YY, Yang Q, Boddu P, Bulkin DA, Warden MR | bioRxiv : the preprint server for biology | 37645876 | bioRxiv | 2024 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/37645876 |
Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice. | Sidor MM, Spencer SM, Dzirasa K, Parekh PK, Tye KM, Warden MR, Arey RN, Enwright JF, Jacobsen JP, Kumar S, Remillard EM, Caron MG, Deisseroth K, McClung CA | Molecular psychiatry | 25687774 | Mol Psychiatry | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25687774 |
Infralimbic parvalbumin neural activity facilitates cued threat avoidance. | Ho YY, Yang Q, Boddu P, Bulkin DA, Warden MR | eLife | 40168058 | Elife | 2025 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/40168058 |
Hebbian Learning in a Random Network Captures Selectivity Properties of the Prefrontal Cortex. | Lindsay GW, Rigotti M, Warden MR, Miller EK, Fusi S | The Journal of neuroscience : the official journal of the Society for Neuroscience | 28986463 | J Neurosci | 2017 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/28986463 |
Serotonin neurons in mating female mice are activated by male ejaculation. | Troconis EL, Seo C, Guru A, Warden MR | Current biology : CB | 37865094 | Curr Biol | 2023 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/37865094 |
Serotonin neurons in mating female mice are activated by male ejaculation. | Troconis EL, Seo C, Guru A, Warden MR | bioRxiv : the preprint server for biology | 37645786 | bioRxiv | 2023 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/37645786 |
Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement. | Corre J, van Zessen R, Loureiro M, Patriarchi T, Tian L, Pascoli V, Lüscher C | eLife | 30373717 | Elife | 2018 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/30373717 |
An expanded palette of dopamine sensors for multiplex imaging in vivo. | Patriarchi T, Mohebi A, Sun J, Marley A, Liang R, Dong C, Puhger K, Mizuno GO, Davis CM, Wiltgen B, von Zastrow M, Berke JD, Tian L | Nature methods | 32895537 | Nat Methods | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32895537 |
Monitoring activity in neural circuits with genetically encoded indicators. | Broussard GJ, Liang R, Tian L | Frontiers in molecular neuroscience | 25538558 | Front Mol Neurosci | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25538558 |
Imaging chemical neurotransmission with genetically encoded fluorescent sensors. | Liang R, Broussard GJ, Tian L | ACS chemical neuroscience | 25565280 | ACS Chem Neurosci | 2015 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/25565280 |
Maps of neuronal activity across the mouse brain. | Andreoni A, Tian L | Nature biomedical engineering | 31073176 | Nat Biomed Eng | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/31073176 |
Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance. | Oe Y, Wang X, Patriarchi T, Konno A, Ozawa K, Yahagi K, Hirai H, Tsuboi T, Kitaguchi T, Tian L, McHugh TJ, Hirase H | Nature communications | 31980655 | Nat Commun | 2020 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/31980655 |
An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. | Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J | Nature chemical biology | 32989297 | Nat Chem Biol | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32989297 |
Imaging voltage and brain chemistry with genetically encoded sensors and modulators. | Pal A, Tian L | Current opinion in chemical biology | 32823064 | Curr Opin Chem Biol | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32823064 |
Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning. | Unger EK, Keller JP, Altermatt M, Liang R, Matsui A, Dong C, Hon OJ, Yao Z, Sun J, Banala S, Flanigan ME, Jaffe DA, Hartanto S, Carlen J, Mizuno GO, Borden PM, Shivange AV, Cameron LP, Sinning S, Underhill SM, Olson DE, Amara SG, Temple Lang D, Rudnick G, Marvin JS, Lavis LD, Lester HA, Alvarez VA, Fisher AJ, Prescher JA, Kash TL, Yarov-Yarovoy V, Gradinaru V, Looger LL, Tian L | Cell | 33333022 | Cell | 2020 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/33333022 |
Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1. | Robinson JE, Coughlin GM, Hori AM, Cho JR, Mackey ED, Turan Z, Patriarchi T, Tian L, Gradinaru V | eLife | 31545171 | Elife | 2019 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/31545171 |
SynQuant: an automatic tool to quantify synapses from microscopy images. | Wang Y, Wang C, Ranefall P, Broussard GJ, Wang Y, Shi G, Lyu B, Wu CT, Wang Y, Tian L, Yu G | Bioinformatics (Oxford, England) | 31596456 | Bioinformatics | 2020 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/31596456 |
Psychedelic-inspired drug discovery using an engineered biosensor. | Dong C, Ly C, Dunlap LE, Vargas MV, Sun J, Hwang IW, Azinfar A, Oh WC, Wetsel WC, Olson DE, Tian L | Cell | 33915107 | Cell | 2021 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/33915107 |
Distinct sub-second dopamine signaling in dorsolateral striatum measured by a genetically-encoded fluorescent sensor. | Salinas AG, Lee JO, Augustin SM, Zhang S, Patriarchi T, Tian L, Morales M, Mateo Y, Lovinger DM | Nature communications | 37739964 | Nat Commun | 2023 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/37739964 |
In vivo measurement of afferent activity with axon-specific calcium imaging. | Broussard GJ, Liang Y, Fridman M, Unger EK, Meng G, Xiao X, Ji N, Petreanu L, Tian L | Nature neuroscience | 30127424 | Nat Neurosci | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30127424 |
Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model. | Mizuno GO, Wang Y, Shi G, Wang Y, Sun J, Papadopoulos S, Broussard GJ, Unger EK, Deng W, Weick J, Bhattacharyya A, Chen CY, Yu G, Looger LL, Tian L | Cell reports | 29996097 | Cell Rep | 2018 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/29996097 |
A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System. | de Jong JW, Afjei SA, Pollak Dorocic I, Peck JR, Liu C, Kim CK, Tian L, Deisseroth K, Lammel S | Neuron | 30503173 | Neuron | 2019 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/30503173 |
Imaging Neurotransmitter and Neuromodulator Dynamics In Vivo with Genetically Encoded Indicators. | Sabatini BL, Tian L | Neuron | 33058762 | Neuron | 2020 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/33058762 |
Nanodelivery of a functional membrane receptor to manipulate cellular phenotype. | Patriarchi T, Shen A, He W, Baikoghli M, Cheng RH, Xiang YK, Coleman MA, Tian L | Scientific reports | 29476125 | Sci Rep | 2018 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/29476125 |
Epigenetic (re)programming of caste-specific behavior in the ant Camponotus floridanus. | Simola DF, Graham RJ, Brady CM, Enzmann BL, Desplan C, Ray A, Zwiebel LJ, Bonasio R, Reinberg D, Liebig J, Berger SL | Science (New York, N.Y.) | 26722000 | Science | 2016 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/26722000 |
High-Quality Genome Assemblies Reveal Long Non-coding RNAs Expressed in Ant Brains. | Shields EJ, Sheng L, Weiner AK, Garcia BA, Bonasio R | Cell reports | 29874592 | Cell Rep | 2018 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/29874592 |
RNA Binding to CBP Stimulates Histone Acetylation and Transcription. | Bose DA, Donahue G, Reinberg D, Shiekhattar R, Bonasio R, Berger SL | Cell | 28086087 | Cell | 2017 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/28086087 |
lncRedibly versatile: biochemical and biological functions of long noncoding RNAs. | Shields EJ, Petracovici AF, Bonasio R | The Biochemical journal | 30971458 | Biochem J | 2019 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/30971458 |
H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. | Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L, Montavon T, Becker JS, Grindheim JM, Blahnik K, Garcia BA, Tan K, Bonasio R, Jenuwein T, Zaret KS | Science (New York, N.Y.) | 30606806 | Science | 2019 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/30606806 |
Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones. | Pask GM, Slone JD, Millar JG, Das P, Moreira JA, Zhou X, Bello J, Berger SL, Bonasio R, Desplan C, Reinberg D, Liebig J, Zwiebel LJ, Ray A | Nature communications | 28819196 | Nat Commun | 2017 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/28819196 |
An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants. | Yan H, Opachaloemphan C, Mancini G, Yang H, Gallitto M, Mlejnek J, Leibholz A, Haight K, Ghaninia M, Huo L, Perry M, Slone J, Zhou X, Traficante M, Penick CA, Dolezal K, Gokhale K, Stevens K, Fetter-Pruneda I, Bonasio R, Zwiebel LJ, Berger SL, Liebig J, Reinberg D, Desplan C | Cell | 28802043 | Cell | 2017 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/28802043 |
The expanding epigenetic landscape of non-model organisms. | Bonasio R | The Journal of experimental biology | 25568458 | J Exp Biol | 2015 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/25568458 |
Delineation of a Human Mendelian Disorder of the DNA Demethylation Machinery: TET3 Deficiency. | Beck DB, Petracovici A, He C, Moore HW, Louie RJ, Ansar M, Douzgou S, Sithambaram S, Cottrell T, Santos-Cortez RLP, Prijoles EJ, Bend R, Keren B, Mignot C, Nougues MC, Õunap K, Reimand T, Pajusalu S, Zahid M, Saqib MAN, Buratti J, Seaby EG, McWalter K, Telegrafi A, Baldridge D, Shinawi M, Leal SM, Schaefer GB, Stevenson RE, Banka S, Bonasio R, Fahrner JA | American journal of human genetics | 31928709 | Am J Hum Genet | 2020 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/31928709 |
Genome annotation with long RNA reads reveals new patterns of gene expression and improves single-cell analyses in an ant brain. | Shields EJ, Sorida M, Sheng L, Sieriebriennikov B, Ding L, Bonasio R | BMC biology | 34838024 | BMC Biol | 2021 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/34838024 |
The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants. | Gospocic J, Shields EJ, Glastad KM, Lin Y, Penick CA, Yan H, Mikheyev AS, Linksvayer TA, Garcia BA, Berger SL, Liebig J, Reinberg D, Bonasio R | Cell | 28802044 | Cell | 2017 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/28802044 |
Social reprogramming in ants induces longevity-associated glia remodeling. | Sheng L, Shields EJ, Gospocic J, Glastad KM, Ratchasanmuang P, Berger SL, Raj A, Little S, Bonasio R | Science advances | 32875108 | Sci Adv | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32875108 |
Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones. | Gospocic J, Glastad KM, Sheng L, Shields EJ, Berger SL, Bonasio R | Cell | 34739833 | Cell | 2021 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/34739833 |
Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2. | Choi J, Lee K, Ingvarsdottir K, Bonasio R, Saraf A, Florens L, Washburn MP, Tadros S, Green MR, Busino L | Nature cell biology | 29695787 | Nat Cell Biol | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29695787 |
Waking up to the alarm: sleep, clocks, and making memory (s)tick. | Gerstner JR, Aton SJ, Heller HC | Frontiers in systems neuroscience | 25954165 | Front Syst Neurosci | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25954165 |
Sleep loss disrupts Arc expression in dentate gyrus neurons. | Delorme JE, Kodoth V, Aton SJ | Neurobiology of learning and memory | 29635031 | Neurobiol Learn Mem | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29635031 |
Erratum: Parvalbumin-expressing interneurons coordinate hippocampal network dynamics required for memory consolidation. | Ognjanovski N, Schaeffer S, Wu J, Mofakham S, Maruyama D, Zochowski M, Aton SJ | Nature communications | 28681846 | Nat Commun | 2017 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/28681846 |
Functional network stability and average minimal distance - A framework to rapidly assess dynamics of functional network representations. | Wu J, Skilling QM, Maruyama D, Li C, Ognjanovski N, Aton S, Zochowski M | Journal of neuroscience methods | 29294309 | J Neurosci Methods | 2018 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/29294309 |
Sleep loss drives acetylcholine- and somatostatin interneuron-mediated gating of hippocampal activity to inhibit memory consolidation. | Delorme J, Wang L, Kuhn FR, Kodoth V, Ma J, Martinez JD, Raven F, Toth BA, Balendran V, Vega Medina A, Jiang S, Aton SJ | Proceedings of the National Academy of Sciences of the United States of America | 34344824 | Proc Natl Acad Sci U S A | 2021 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/34344824 |
Theta-gamma coupling emerges from spatially heterogeneous cholinergic neuromodulation. | Yang Y, Gritton H, Sarter M, Aton SJ, Booth V, Zochowski M | PLoS computational biology | 34329297 | PLoS Comput Biol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34329297 |
Sleep Promotes, and Sleep Loss Inhibits, Selective Changes in Firing Rate, Response Properties and Functional Connectivity of Primary Visual Cortex Neurons. | Clawson BC, Durkin J, Suresh AK, Pickup EJ, Broussard CG, Aton SJ | Frontiers in systems neuroscience | 30245617 | Front Syst Neurosci | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30245617 |
Hippocampal Network Oscillations Rescue Memory Consolidation Deficits Caused by Sleep Loss. | Ognjanovski N, Broussard C, Zochowski M, Aton SJ | Cerebral cortex (New York, N.Y. : 1991) | 30060138 | Cereb Cortex | 2018 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/30060138 |
CA1 hippocampal network activity changes during sleep-dependent memory consolidation. | Ognjanovski N, Maruyama D, Lashner N, Zochowski M, Aton SJ | Frontiers in systems neuroscience | 24860440 | Front Syst Neurosci | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24860440 |
The role of clock genes in sleep, stress and memory. | Bolsius YG, Zurbriggen MD, Kim JK, Kas MJ, Meerlo P, Aton SJ, Havekes R | Biochemical pharmacology | 33647263 | Biochem Pharmacol | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/33647263 |
Sleep Loss Drives Brain Region-Specific and Cell Type-Specific Alterations in Ribosome-Associated Transcripts Involved in Synaptic Plasticity and Cellular Timekeeping. | Puentes-Mestril C, Delorme J, Wang L, Donnelly M, Popke D, Jiang S, Aton SJ | The Journal of neuroscience : the official journal of the Society for Neuroscience | 34001629 | J Neurosci | 2021 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/34001629 |
Set and setting: how behavioral state regulates sensory function and plasticity. | Aton SJ | Neurobiology of learning and memory | 23792020 | Neurobiol Learn Mem | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23792020 |
Resonance with subthreshold oscillatory drive organizes activity and optimizes learning in neural networks. | Roach JP, Pidde A, Katz E, Wu J, Ognjanovski N, Aton SJ, Zochowski MR | Proceedings of the National Academy of Sciences of the United States of America | 29545273 | Proc Natl Acad Sci U S A | 2018 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/29545273 |
Hippocampal neurons' cytosolic and membrane-bound ribosomal transcript profiles are differentially regulated by learning and subsequent sleep. | Delorme J, Wang L, Kodoth V, Wang Y, Ma J, Jiang S, Aton SJ | Proceedings of the National Academy of Sciences of the United States of America | 34819370 | Proc Natl Acad Sci U S A | 2021 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/34819370 |
Hypnotic treatment reverses NREM sleep disruption and EEG desynchronization in a mouse model of Fragile X syndrome to rescue memory consolidation deficits. | Martinez JD, Wilson LG, Brancaleone WP, Peterson KG, Popke DS, Garzon VC, Perez Tremble RE, Donnelly MJ, Mendez Ortega SL, Torres D, Shaver JJ, Clawson BC, Jiang S, Yang Z, Aton SJ | bioRxiv : the preprint server for biology | 37502832 | bioRxiv | 2023 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/37502832 |
Sleep deprivation during a specific 3-hour time window post-training impairs hippocampal synaptic plasticity and memory. | Prince TM, Wimmer M, Choi J, Havekes R, Aton S, Abel T | Neurobiology of learning and memory | 24380868 | Neurobiol Learn Mem | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24380868 |
Form and Function of Sleep Spindles across the Lifespan. | Clawson BC, Durkin J, Aton SJ | Neural plasticity | 27190654 | Neural Plast | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27190654 |
Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1. | Havekes R, Park AJ, Tudor JC, Luczak VG, Hansen RT, Ferri SL, Bruinenberg VM, Poplawski SG, Day JP, Aton SJ, Radwańska K, Meerlo P, Houslay MD, Baillie GS, Abel T | eLife | 27549340 | Elife | 2016 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/27549340 |
Editorial-Methods and models in sleep research. | Aton SJ, Di Giovanni G, Leresche N | Journal of neuroscience methods | 30576680 | J Neurosci Methods | 2019 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/30576680 |
Parvalbumin-expressing interneurons coordinate hippocampal network dynamics required for memory consolidation. | Ognjanovski N, Schaeffer S, Wu J, Mofakham S, Maruyama D, Zochowski M, Aton SJ | Nature communications | 28382952 | Nat Commun | 2017 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/28382952 |
Hypnotic treatment improves sleep architecture and EEG disruptions and rescues memory deficits in a mouse model of fragile X syndrome. | Martinez JD, Wilson LG, Brancaleone WP, Peterson KG, Popke DS, Garzon VC, Perez Tremble RE, Donnelly MJ, Mendez Ortega SL, Torres D, Shaver JJ, Jiang S, Yang Z, Aton SJ | Cell reports | 38787724 | Cell Rep | 2024 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/38787724 |
Linking Network Activity to Synaptic Plasticity during Sleep: Hypotheses and Recent Data. | Puentes-Mestril C, Aton SJ | Frontiers in neural circuits | 28932187 | Front Neural Circuits | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28932187 |
Acetylcholine-gated current translates wake neuronal firing rate information into a spike timing-based code in Non-REM sleep, stabilizing neural network dynamics during memory consolidation. | Skilling QM, Eniwaye B, Clawson BC, Shaver J, Ognjanovski N, Aton SJ, Zochowski M | PLoS computational biology | 34543284 | PLoS Comput Biol | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34543284 |
New dimensions and new tools to realize the potential of RDoC: digital phenotyping via smartphones and connected devices. | Torous J, Onnela JP, Keshavan M | Translational psychiatry | 28267146 | Transl Psychiatry | 2017 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/28267146 |
Inferring mobility measures from GPS traces with missing data. | Barnett I, Onnela JP | Biostatistics (Oxford, England) | 30371736 | Biostatistics | 2020 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/30371736 |
Smartphone-based Assessment of Preoperative Decision Conflict and Postoperative Physical Activity Among Patients Undergoing Cancer Surgery: A Prospective Cohort Study. | Panda N, Solsky I, Cauley CE, Lipsitz S, Desai EV, Huang EJ, Benjamin EM, Lubitz CC, Onnela JP, Haynes AB | Annals of surgery | 32941270 | Ann Surg | 2022 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/32941270 |
Smartphone Global Positioning System (GPS) Data Enhances Recovery Assessment After Breast Cancer Surgery. | Panda N, Solsky I, Hawrusik B, Liu G, Reeder H, Lipsitz S, Desai EV, Lowery KW, Miller K, Gadd MA, Lubitz CC, Smith BL, Specht M, Onnela JP, Haynes AB | Annals of surgical oncology | 32812109 | Ann Surg Oncol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32812109 |
A comparison of passive and active estimates of sleep in a cohort with schizophrenia. | Staples P, Torous J, Barnett I, Carlson K, Sandoval L, Keshavan M, Onnela JP | NPJ schizophrenia | 29038553 | NPJ Schizophr | 2017 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/29038553 |
A crossroad for validating digital tools in schizophrenia and mental health. | Torous J, Staples P, Barnett I, Onnela JP, Keshavan M | NPJ schizophrenia | 29626190 | NPJ Schizophr | 2018 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/29626190 |
Augmented Movelet Method for Activity Classification Using Smartphone Gyroscope and Accelerometer Data. | Huang EJ, Onnela JP | Sensors (Basel, Switzerland) | 32630752 | Sensors (Basel) | 2020 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/32630752 |
Digital Phenotyping to Quantify Psychosocial Well-Being Trajectories After Spinal Cord Injury. | Mercier HW, Hamner JW, Torous J, Onnela JP, Taylor JA | American journal of physical medicine & rehabilitation | 32576743 | Am J Phys Med Rehabil | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32576743 |
Sociodemographic characteristics of missing data in digital phenotyping. | Kiang MV, Chen JT, Krieger N, Buckee CO, Alexander MJ, Baker JT, Buckner RL, Coombs G 3rd, Rich-Edwards JW, Carlson KW, Onnela JP | Scientific reports | 34326370 | Sci Rep | 2021 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/34326370 |
Open-source Longitudinal Sleep Analysis From Accelerometer Data (DPSleep): Algorithm Development and Validation. | Rahimi-Eichi H, Coombs Iii G, Vidal Bustamante CM, Onnela JP, Baker JT, Buckner RL | JMIR mHealth and uHealth | 34612831 | JMIR Mhealth Uhealth | 2021 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/34612831 |
Harnessing Smartphone-Based Digital Phenotyping to Enhance Behavioral and Mental Health. | Onnela JP, Rauch SL | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 26818126 | Neuropsychopharmacology | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26818126 |
Fluctuations in behavior and affect in college students measured using deep phenotyping. | Vidal Bustamante CM, Coombs G 3rd, Rahimi-Eichi H, Mair P, Onnela JP, Baker JT, Buckner RL | Scientific reports | 35121741 | Sci Rep | 2022 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/35121741 |
Estimating longitudinal depressive symptoms from smartphone data in a transdiagnostic cohort. | Pellegrini AM, Huang EJ, Staples PC, Hart KL, Lorme JM, Brown HE, Perlis RH, Onnela JJ | Brain and behavior | 35076166 | Brain Behav | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35076166 |
The relationship of rate and pause features to the communicative participation of people living with ALS. | Connaghan KP, Green JR, Eshghi M, Haenssler AE, Scheier ZA, Clark A, Iyer A, Richburg BD, Rowe HP, Okada J, Johnson SA, Onnela JP, Burke KM, Berry JD | Muscle & nerve | 38837773 | Muscle Nerve | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38837773 |
Determining sample size and length of follow-up for smartphone-based digital phenotyping studies. | Barnett I, Torous J, Reeder HT, Baker J, Onnela JP | Journal of the American Medical Informatics Association : JAMIA | 33043370 | J Am Med Inform Assoc | 2020 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/33043370 |
High potential but limited evidence: Using voice data from smartphones to monitor and diagnose mood disorders. | Or F, Torous J, Onnela JP | Psychiatric rehabilitation journal | 28891659 | Psychiatr Rehabil J | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28891659 |
Characterizing the clinical relevance of digital phenotyping data quality with applications to a cohort with schizophrenia. | Torous J, Staples P, Barnett I, Sandoval LR, Keshavan M, Onnela JP | NPJ digital medicine | 31304300 | NPJ Digit Med | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/31304300 |
Beyond smartphones and sensors: choosing appropriate statistical methods for the analysis of longitudinal data. | Barnett I, Torous J, Staples P, Keshavan M, Onnela JP | Journal of the American Medical Informatics Association : JAMIA | 30272176 | J Am Med Inform Assoc | 2018 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/30272176 |
Realizing the potential of mobile mental health: new methods for new data in psychiatry. | Torous J, Staples P, Onnela JP | Current psychiatry reports | 26073363 | Curr Psychiatry Rep | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26073363 |
New Tools for New Research in Psychiatry: A Scalable and Customizable Platform to Empower Data Driven Smartphone Research. | Torous J, Kiang MV, Lorme J, Onnela JP | JMIR mental health | 27150677 | JMIR Ment Health | 2016 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/27150677 |
Smartphone-Based Tracking of Sleep in Depression, Anxiety, and Psychotic Disorders. | Aledavood T, Torous J, Triana Hoyos AM, Naslund JA, Onnela JP, Keshavan M | Current psychiatry reports | 31161412 | Curr Psychiatry Rep | 2019 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/31161412 |
Precision Assessment of Real-World Associations Between Stress and Sleep Duration Using Actigraphy Data Collected Continuously for an Academic Year: Individual-Level Modeling Study. | Vidal Bustamante CM, Coombs Iii G, Rahimi-Eichi H, Mair P, Onnela JP, Baker JT, Buckner RL | JMIR formative research | 38687600 | JMIR Form Res | 2024 Apr 30 | https://www.ncbi.nlm.nih.gov/pubmed/38687600 |
Utilizing a Personal Smartphone Custom App to Assess the Patient Health Questionnaire-9 (PHQ-9) Depressive Symptoms in Patients With Major Depressive Disorder. | Torous J, Staples P, Shanahan M, Lin C, Peck P, Keshavan M, Onnela JP | JMIR mental health | 26543914 | JMIR Ment Health | 2015 Jan-Mar | https://www.ncbi.nlm.nih.gov/pubmed/26543914 |
EndNote: Feature-based classification of networks. | Barnett I, Malik N, Kuijjer ML, Mucha PJ, Onnela JP | Network science (Cambridge University Press) | 31984135 | Netw Sci (Camb Univ Press) | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31984135 |
Expected Versus Experienced Health-Related Quality of Life Among Patients Recovering From Cancer Surgery: A Prospective Cohort Study. | Panda N, Solsky I, Neal BJ, Hawrusik B, Lipsitz S, Lubitz CC, Gibbons C, Brindle M, Sinyard RD, Onnela JP, Cauley CE, Haynes AB | Annals of surgery open : perspectives of surgical history, education, and clinical approaches | 34179891 | Ann Surg Open | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34179891 |
Understanding the quality, effectiveness and attributes of top-rated smartphone health apps. | Wisniewski H, Liu G, Henson P, Vaidyam A, Hajratalli NK, Onnela JP, Torous J | Evidence-based mental health | 30635262 | Evid Based Ment Health | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30635262 |
The HOPE Pilot Study: Harnessing Patient-Reported Outcomes and Biometric Data to Enhance Cancer Care. | Wright AA, Raman N, Staples P, Schonholz S, Cronin A, Carlson K, Keating NL, Onnela JP | JCO clinical cancer informatics | 30652585 | JCO Clin Cancer Inform | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30652585 |
Design and results of a smartphone-based digital phenotyping study to quantify ALS progression. | Berry JD, Paganoni S, Carlson K, Burke K, Weber H, Staples P, Salinas J, Chan J, Green JR, Connaghan K, Barback J, Onnela JP | Annals of clinical and translational neurology | 31139685 | Ann Clin Transl Neurol | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/31139685 |
Relapse prediction in schizophrenia through digital phenotyping: a pilot study. | Barnett I, Torous J, Staples P, Sandoval L, Keshavan M, Onnela JP | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 29511333 | Neuropsychopharmacology | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29511333 |
Methodology and Reporting of Mobile Heath and Smartphone Application Studies for Schizophrenia. | Torous J, Firth J, Mueller N, Onnela JP, Baker JT | Harvard review of psychiatry | 28234658 | Harv Rev Psychiatry | 2017 May/Jun | https://www.ncbi.nlm.nih.gov/pubmed/28234658 |
Microglia states and nomenclature: A field at its crossroads. | Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Brône B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, González B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T | Neuron | 36327895 | Neuron | 2022 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/36327895 |
G9a influences neuronal subtype specification in striatum. | Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Daws SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL, Hurd YL, Shen L, Han MH, Schaefer A, Nestler EJ | Nature neuroscience | 24584053 | Nat Neurosci | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24584053 |
The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System. | Cholewa-Waclaw J, Bird A, von Schimmelmann M, Schaefer A, Yu H, Song H, Madabhushi R, Tsai LH | The Journal of neuroscience : the official journal of the Society for Neuroscience | 27911745 | J Neurosci | 2016 Nov 9 | https://www.ncbi.nlm.nih.gov/pubmed/27911745 |
Microglia enable cross-modal plasticity by removing inhibitory synapses. | Hashimoto A, Kawamura N, Tarusawa E, Takeda I, Aoyama Y, Ohno N, Inoue M, Kagamiuchi M, Kato D, Matsumoto M, Hasegawa Y, Nabekura J, Schaefer A, Moorhouse AJ, Yagi T, Wake H | Cell reports | 37086724 | Cell Rep | 2023 May 30 | https://www.ncbi.nlm.nih.gov/pubmed/37086724 |
An AUTS2-Polycomb complex activates gene expression in the CNS. | Gao Z, Lee P, Stafford JM, von Schimmelmann M, Schaefer A, Reinberg D | Nature | 25519132 | Nature | 2014 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/25519132 |
Negative feedback control of neuronal activity by microglia. | Badimon A, Strasburger HJ, Ayata P, Chen X, Nair A, Ikegami A, Hwang P, Chan AT, Graves SM, Uweru JO, Ledderose C, Kutlu MG, Wheeler MA, Kahan A, Ishikawa M, Wang YC, Loh YE, Jiang JX, Surmeier DJ, Robson SC, Junger WG, Sebra R, Calipari ES, Kenny PJ, Eyo UB, Colonna M, Quintana FJ, Wake H, Gradinaru V, Schaefer A | Nature | 32999463 | Nature | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32999463 |
Autism-like syndrome is induced by pharmacological suppression of BET proteins in young mice. | Sullivan JM, Badimon A, Schaefer U, Ayata P, Gray J, Chung CW, von Schimmelmann M, Zhang F, Garton N, Smithers N, Lewis H, Tarakhovsky A, Prinjha RK, Schaefer A | The Journal of experimental medicine | 26392221 | J Exp Med | 2015 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/26392221 |
A comparative analysis of microglial inducible Cre lines. | Faust TE, Feinberg PA, O'Connor C, Kawaguchi R, Chan A, Strasburger H, Frosch M, Boyle MA, Masuda T, Amann L, Knobeloch KP, Prinz M, Schaefer A, Schafer DP | Cell reports | 37635351 | Cell Rep | 2023 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/37635351 |
MicroRNA-128 governs neuronal excitability and motor behavior in mice. | Tan CL, Plotkin JL, Venø MT, von Schimmelmann M, Feinberg P, Mann S, Handler A, Kjems J, Surmeier DJ, O'Carroll D, Greengard P, Schaefer A | Science (New York, N.Y.) | 24311694 | Science | 2013 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/24311694 |
CSF-1 controls cerebellar microglia and is required for motor function and social interaction. | Kana V, Desland FA, Casanova-Acebes M, Ayata P, Badimon A, Nabel E, Yamamuro K, Sneeboer M, Tan IL, Flanigan ME, Rose SA, Chang C, Leader A, Le Bourhis H, Sweet ES, Tung N, Wroblewska A, Lavin Y, See P, Baccarini A, Ginhoux F, Chitu V, Stanley ER, Russo SJ, Yue Z, Brown BD, Joyner AL, De Witte LD, Morishita H, Schaefer A, Merad M | The Journal of experimental medicine | 31350310 | J Exp Med | 2019 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/31350310 |
Convergence of spectrums: neuronal gene network states in autism spectrum disorder. | Sullivan JM, De Rubeis S, Schaefer A | Current opinion in neurobiology | 31220745 | Curr Opin Neurobiol | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31220745 |
Epigenetic regulation of brain region-specific microglia clearance activity. | Ayata P, Badimon A, Strasburger HJ, Duff MK, Montgomery SE, Loh YE, Ebert A, Pimenova AA, Ramirez BR, Chan AT, Sullivan JM, Purushothaman I, Scarpa JR, Goate AM, Busslinger M, Shen L, Losic B, Schaefer A | Nature neuroscience | 30038282 | Nat Neurosci | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30038282 |
Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration. | von Schimmelmann M, Feinberg PA, Sullivan JM, Ku SM, Badimon A, Duff MK, Wang Z, Lachmann A, Dewell S, Ma'ayan A, Han MH, Tarakhovsky A, Schaefer A | Nature neuroscience | 27526204 | Nat Neurosci | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27526204 |
Argonaute-associated short introns are a novel class of gene regulators. | Hansen TB, Venø MT, Jensen TI, Schaefer A, Damgaard CK, Kjems J | Nature communications | 27173734 | Nat Commun | 2016 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/27173734 |
Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion. | Meda KS, Patel T, Braz JM, Malik R, Turner ML, Seifikar H, Basbaum AI, Sohal VS | Neuron | 31030955 | Neuron | 2019 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/31030955 |
Identifying specific prefrontal neurons that contribute to autism-associated abnormalities in physiology and social behavior. | Brumback AC, Ellwood IT, Kjaerby C, Iafrati J, Robinson S, Lee AT, Patel T, Nagaraj S, Davatolhagh F, Sohal VS | Molecular psychiatry | 29112191 | Mol Psychiatry | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29112191 |
Dynamic, Cell-Type-Specific Roles for GABAergic Interneurons in a Mouse Model of Optogenetically Inducible Seizures. | Khoshkhoo S, Vogt D, Sohal VS | Neuron | 28041880 | Neuron | 2017 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/28041880 |
VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks. | Lee AT, Cunniff MM, See JZ, Wilke SA, Luongo FJ, Ellwood IT, Ponnavolu S, Sohal VS | Neuron | 31053407 | Neuron | 2019 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/31053407 |
Pyramidal neurons in prefrontal cortex receive subtype-specific forms of excitation and inhibition. | Lee AT, Gee SM, Vogt D, Patel T, Rubenstein JL, Sohal VS | Neuron | 24361076 | Neuron | 2014 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/24361076 |
Serotonin 1B Receptors Regulate Prefrontal Function by Gating Callosal and Hippocampal Inputs. | Kjaerby C, Athilingam J, Robinson SE, Iafrati J, Sohal VS | Cell reports | 27974203 | Cell Rep | 2016 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/27974203 |
Tonic or Phasic Stimulation of Dopaminergic Projections to Prefrontal Cortex Causes Mice to Maintain or Deviate from Previously Learned Behavioral Strategies. | Ellwood IT, Patel T, Wadia V, Lee AT, Liptak AT, Bender KJ, Sohal VS | The Journal of neuroscience : the official journal of the Society for Neuroscience | 28739583 | J Neurosci | 2017 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/28739583 |
The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles. | Vogt D, Cho KKA, Lee AT, Sohal VS, Rubenstein JLR | Cell reports | 25937288 | Cell Rep | 2015 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/25937288 |
Correlations between prefrontal neurons form a small-world network that optimizes the generation of multineuron sequences of activity. | Luongo FJ, Zimmerman CA, Horn ME, Sohal VS | Journal of neurophysiology | 26888108 | J Neurophysiol | 2016 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/26888108 |
Interneuron Transplantation Rescues Social Behavior Deficits without Restoring Wild-Type Physiology in a Mouse Model of Autism with Excessive Synaptic Inhibition. | Southwell DG, Seifikar H, Malik R, Lavi K, Vogt D, Rubenstein JL, Sohal VS | The Journal of neuroscience : the official journal of the Society for Neuroscience | 31988060 | J Neurosci | 2020 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/31988060 |
Gamma rhythms link prefrontal interneuron dysfunction with cognitive inflexibility in Dlx5/6(+/-) mice. | Cho KK, Hoch R, Lee AT, Patel T, Rubenstein JL, Sohal VS | Neuron | 25754826 | Neuron | 2015 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/25754826 |
Roles of Prefrontal Cortex and Mediodorsal Thalamus in Task Engagement and Behavioral Flexibility. | Marton TF, Seifikar H, Luongo FJ, Lee AT, Sohal VS | The Journal of neuroscience : the official journal of the Society for Neuroscience | 29437889 | J Neurosci | 2018 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/29437889 |
Putative Microcircuit-Level Substrates for Attention Are Disrupted in Mouse Models of Autism. | Luongo FJ, Horn ME, Sohal VS | Biological psychiatry | 26022075 | Biol Psychiatry | 2016 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/26022075 |
Resolving the 22q11.2 deletion using CTLR-Seq reveals chromosomal rearrangement mechanisms and individual variance in breakpoints. | Zhou B, Purmann C, Guo H, Shin G, Huang Y, Pattni R, Meng Q, Greer SU, Roychowdhury T, Wood RN, Ho M, Dohna HZ, Abyzov A, Hallmayer JF, Wong WH, Ji HP, Urban AE | Proceedings of the National Academy of Sciences of the United States of America | 39042694 | Proc Natl Acad Sci U S A | 2024 Jul 30 | https://www.ncbi.nlm.nih.gov/pubmed/39042694 |
Comprehensive performance comparison of high-resolution array platforms for genome-wide Copy Number Variation (CNV) analysis in humans. | Haraksingh RR, Abyzov A, Urban AE | BMC genomics | 28438122 | BMC Genomics | 2017 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/28438122 |
Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders. | Li J, Ma Z, Shi M, Malty RH, Aoki H, Minic Z, Phanse S, Jin K, Wall DP, Zhang Z, Urban AE, Hallmayer J, Babu M, Snyder M | Cell systems | 26949739 | Cell Syst | 2015 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/26949739 |
Network Effects of the 15q13.3 Microdeletion on the Transcriptome and Epigenome in Human-Induced Neurons. | Zhang S, Zhang X, Purmann C, Ma S, Shrestha A, Davis KN, Ho M, Huang Y, Pattni R, Wong WH, Bernstein JA, Hallmayer J, Urban AE | Biological psychiatry | 32919612 | Biol Psychiatry | 2021 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/32919612 |
Local and global chromatin interactions are altered by large genomic deletions associated with human brain development. | Zhang X, Zhang Y, Zhu X, Purmann C, Haney MS, Ward T, Khechaduri A, Yao J, Weissman SM, Urban AE | Nature communications | 30559385 | Nat Commun | 2018 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/30559385 |
Mutations in human DNA methyltransferase DNMT1 induce specific genome-wide epigenomic and transcriptomic changes in neurodevelopment. | Davis KN, Qu PP, Ma S, Lin L, Plastini M, Dahl N, Plazzi G, Pizza F, O'Hara R, Wong WH, Hallmayer J, Mignot E, Zhang X, Urban AE | Human molecular genetics | 37584462 | Hum Mol Genet | 2023 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/37584462 |
Seizure Action Plans Do Not Reduce Health Care Utilization in Pediatric Epilepsy Patients. | Roundy LM, Filloux FM, Kerr L, Rimer A, Bonkowsky JL | Journal of child neurology | 26245799 | J Child Neurol | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26245799 |
Targeted leukodystrophy diagnosis based on charges and yields for testing. | Richards J, Korgenski EK, Taft RJ, Vanderver A, Bonkowsky JL | American journal of medical genetics. Part A | 26183797 | Am J Med Genet A | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26183797 |
Revised consensus statement on the preventive and symptomatic care of patients with leukodystrophies. | Adang LA, Sherbini O, Ball L, Bloom M, Darbari A, Amartino H, DiVito D, Eichler F, Escolar M, Evans SH, Fatemi A, Fraser J, Hollowell L, Jaffe N, Joseph C, Karpinski M, Keller S, Maddock R, Mancilla E, McClary B, Mertz J, Morgart K, Langan T, Leventer R, Parikh S, Pizzino A, Prange E, Renaud DL, Rizzo W, Shapiro J, Suhr D, Suhr T, Tonduti D, Waggoner J, Waldman A, Wolf NI, Zerem A, Bonkowsky JL, Bernard G, van Haren K, Vanderver A, Global Leukodystrophy Initiative (GLIA) Consortium | Molecular genetics and metabolism | 28863857 | Mol Genet Metab | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28863857 |
A zebrafish model of X-linked adrenoleukodystrophy recapitulates key disease features and demonstrates a developmental requirement for abcd1 in oligodendrocyte patterning and myelination. | Strachan LR, Stevenson TJ, Freshner B, Keefe MD, Miranda Bowles D, Bonkowsky JL | Human molecular genetics | 28911205 | Hum Mol Genet | 2017 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/28911205 |
National variation in costs and mortality for leukodystrophy patients in US children's hospitals. | Brimley CJ, Lopez J, van Haren K, Wilkes J, Sheng X, Nelson C, Korgenski EK, Srivastava R, Bonkowsky JL | Pediatric neurology | 23953952 | Pediatr Neurol | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23953952 |
Autism Spectrum Disorder and Neonatal Serum Magnesium Levels in Preterm Infants. | Bakian AV, Bilder DA, Korgenski EK, Bonkowsky JL | Child neurology open | 30246047 | Child Neurol Open | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30246047 |
A Serotonin Circuit Acts as an Environmental Sensor to Mediate Midline Axon Crossing through EphrinB2. | Xing L, Son JH, Stevenson TJ, Lillesaar C, Bally-Cuif L, Dahl T, Bonkowsky JL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 26538650 | J Neurosci | 2015 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/26538650 |
The Midline Axon Crossing Decision Is Regulated through an Activity-Dependent Mechanism by the NMDA Receptor. | Gao J, Stevenson TJ, Douglass AD, Barrios JP, Bonkowsky JL | eNeuro | 29766040 | eNeuro | 2018 Mar-Apr | https://www.ncbi.nlm.nih.gov/pubmed/29766040 |
Intrapartum magnesium sulfate and the potential for cardiopulmonary drug-drug interactions. | Campbell SC, Stockmann C, Balch A, Clark EA, Kamyar M, Varner M, Korgenski EK, Bonkowsky JL, Spigarelli MG, Sherwin CM | Therapeutic drug monitoring | 24487252 | Ther Drug Monit | 2014 Aug | https://www.ncbi.nlm.nih.gov/pubmed/24487252 |
Neonatal magnesium levels correlate with motor outcomes in premature infants: a long-term retrospective cohort study. | Doll E, Wilkes J, Cook LJ, Korgenski EK, Faix RG, Yoder BA, Srivastava R, Sherwin CM, Spigarelli MG, Clark EA, Bonkowsky JL | Frontiers in pediatrics | 25414842 | Front Pediatr | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25414842 |
Temporal Dysynchrony in brain connectivity gene expression following hypoxia. | Milash B, Gao J, Stevenson TJ, Son JH, Dahl T, Bonkowsky JL | BMC genomics | 27146468 | BMC Genomics | 2016 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/27146468 |
An automated system for rapid cellular extraction from live zebrafish embryos and larvae: Development and application to genotyping. | Lambert CJ, Freshner BC, Chung A, Stevenson TJ, Bowles DM, Samuel R, Gale BK, Bonkowsky JL | PloS one | 29543903 | PLoS One | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29543903 |
The conserved dopaminergic diencephalospinal tract mediates vertebrate locomotor development in zebrafish larvae. | Lambert AM, Bonkowsky JL, Masino MA | The Journal of neuroscience : the official journal of the Society for Neuroscience | 23015438 | J Neurosci | 2012 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/23015438 |
Neurodegeneration in a Drosophila model of adrenoleukodystrophy: the roles of the Bubblegum and Double bubble acyl-CoA synthetases. | Sivachenko A, Gordon HB, Kimball SS, Gavin EJ, Bonkowsky JL, Letsou A | Disease models & mechanisms | 26893370 | Dis Model Mech | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26893370 |
Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. | Schweitzer J, Löhr H, Bonkowsky JL, Hübscher K, Driever W | Development (Cambridge, England) | 23222439 | Development | 2013 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/23222439 |
Rapid and efficient zebrafish genotyping using PCR with high-resolution melt analysis. | Xing L, Quist TS, Stevenson TJ, Dahlem TJ, Bonkowsky JL | Journal of visualized experiments : JoVE | 24561516 | J Vis Exp | 2014 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/24561516 |
Determinants of health care use in a population-based leukodystrophy cohort. | Nelson C, Mundorff MB, Korgenski EK, Brimley CJ, Srivastava R, Bonkowsky JL | The Journal of pediatrics | 23069195 | J Pediatr | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23069195 |
Expression of arginine vasotocin receptors in the developing zebrafish CNS. | Iwasaki K, Taguchi M, Bonkowsky JL, Kuwada JY | Gene expression patterns : GEP | 23830982 | Gene Expr Patterns | 2013 Dec | https://www.ncbi.nlm.nih.gov/pubmed/23830982 |
Neonatal Magnesium Levels Between 24 and 48 Hours of Life and Outcomes for Epilepsy and Motor Impairment in Premature Infants. | Ostrander B, Bardsley T, Korgenski EK, Greene T, Bonkowsky JL | Pediatric neurology | 27025188 | Pediatr Neurol | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27025188 |
Transgenic FingRs for Live Mapping of Synaptic Dynamics in Genetically-Defined Neurons. | Son JH, Keefe MD, Stevenson TJ, Barrios JP, Anjewierden S, Newton JB, Douglass AD, Bonkowsky JL | Scientific reports | 26728131 | Sci Rep | 2016 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/26728131 |
A Novel Developmental Role for Dopaminergic Signaling to Specify Hypothalamic Neurotransmitter Identity. | Chen YC, Semenova S, Rozov S, Sundvik M, Bonkowsky JL, Panula P | The Journal of biological chemistry | 27539857 | J Biol Chem | 2016 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/27539857 |
Chiari I Malformation Causing Developmental Regression in a 4 Month Old. | Doll ES, Bonkowsky JL, Brown LL, de Havenon AH, Brockmeyer DL, Glasgow TS, Morita DC | Global pediatric health | 27335920 | Glob Pediatr Health | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/27335920 |
Whole-genome analysis for effective clinical diagnosis and gene discovery in early infantile epileptic encephalopathy. | Ostrander BEP, Butterfield RJ, Pedersen BS, Farrell AJ, Layer RM, Ward A, Miller C, DiSera T, Filloux FM, Candee MS, Newcomb T, Bonkowsky JL, Marth GT, Quinlan AR | NPJ genomic medicine | 30109124 | NPJ Genom Med | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30109124 |
Rapid clinical diagnostic variant investigation of genomic patient sequencing data with iobio web tools. | Ward A, Karren MA, Di Sera T, Miller C, Velinder M, Qiao Y, Filloux FM, Ostrander B, Butterfield R, Bonkowsky JL, Dere W, Marth GT | Journal of clinical and translational science | 29707261 | J Clin Transl Sci | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29707261 |
Costs of the diagnostic odyssey in children with inherited leukodystrophies. | Richards J, Korgenski EK, Srivastava R, Bonkowsky JL | Neurology | 26320197 | Neurology | 2015 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/26320197 |
Motor Behavior Mediated by Continuously Generated Dopaminergic Neurons in the Zebrafish Hypothalamus Recovers after Cell Ablation. | McPherson AD, Barrios JP, Luks-Morgan SJ, Manfredi JP, Bonkowsky JL, Douglass AD, Dorsky RI | Current biology : CB | 26774784 | Curr Biol | 2016 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/26774784 |
Maternal magnesium sulphate exposure predicts neonatal magnesium blood concentrations. | Sherwin CM, Balch A, Campbell SC, Fredrickson J, Clark EA, Varner M, Stockmann C, Korgenski EK, Bonkowsky JL, Spigarelli MG | Basic & clinical pharmacology & toxicology | 24164968 | Basic Clin Pharmacol Toxicol | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24164968 |
Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis. | Butterfield RJ, Stevenson TJ, Xing L, Newcomb TM, Nelson B, Zeng W, Li X, Lu HM, Lu H, Farwell Gonzalez KD, Wei JP, Chao EC, Prior TW, Snyder PJ, Bonkowsky JL, Swoboda KJ | Neurology | 24647030 | Neurology | 2014 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/24647030 |
Clinical exome sequencing identifies a novel TUBB4A mutation in a child with static hypomyelinating leukodystrophy. | Purnell SM, Bleyl SB, Bonkowsky JL | Pediatric neurology | 24742798 | Pediatr Neurol | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24742798 |
Preventable Infections in Children with Leukodystrophy. | Anderson HM, Wilkes J, Korgenski EK, Pulsipher MA, Blaschke AJ, Hersh AL, Srivastava R, Bonkowsky JL | Annals of clinical and translational neurology | 24955379 | Ann Clin Transl Neurol | 2014 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/24955379 |
Microfluidic-aided genotyping of zebrafish in the first 48 h with 100% viability. | Samuel R, Stephenson R, Roy P, Pryor R, Zhou L, Bonkowsky JL, Gale BK | Biomedical microdevices | 25773537 | Biomed Microdevices | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25773537 |
Dopaminergic Co-Regulation of Locomotor Development and Motor Neuron Synaptogenesis is Uncoupled by Hypoxia in Zebrafish. | Son JH, Stevenson TJ, Bowles MD, Scholl EA, Bonkowsky JL | eNeuro | 32001551 | eNeuro | 2020 Jan/Feb | https://www.ncbi.nlm.nih.gov/pubmed/32001551 |
Hypothalamic radial glia function as self-renewing neural progenitors in the absence of Wnt/β-catenin signaling. | Duncan RN, Xie Y, McPherson AD, Taibi AV, Bonkowsky JL, Douglass AD, Dorsky RI | Development (Cambridge, England) | 26603385 | Development | 2016 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/26603385 |
Disease specific therapies in leukodystrophies and leukoencephalopathies. | Helman G, Van Haren K, Bonkowsky JL, Bernard G, Pizzino A, Braverman N, Suhr D, Patterson MC, Ali Fatemi S, Leonard J, van der Knaap MS, Back SA, Damiani S, Goldman SA, Takanohashi A, Petryniak M, Rowitch D, Messing A, Wrabetz L, Schiffmann R, Eichler F, Escolar ML, Vanderver A, GLIA Consortium | Molecular genetics and metabolism | 25684057 | Mol Genet Metab | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25684057 |
Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP(+) exposure. | Dukes AA, Bai Q, Van Laar VS, Zhou Y, Ilin V, David CN, Agim ZS, Bonkowsky JL, Cannon JR, Watkins SC, Croix CM, Burton EA, Berman SB | Neurobiology of disease | 27452482 | Neurobiol Dis | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27452482 |
The impact of the COVID-19 pandemic on patients' experiences obtaining a tuberculosis diagnosis in Peru: a mixed-methods study. | Millones AK, Lecca L, Acosta D, Campos H, Del Águila-Rojas E, Farroñay S, Morales G, Ramirez-Sandoval J, Torres I, Jimenez J, Yuen CM | BMC infectious diseases | 36352374 | BMC Infect Dis | 2022 Nov 9 | https://www.ncbi.nlm.nih.gov/pubmed/36352374 |
Identifying barriers and facilitators to implementation of community-based tuberculosis active case finding with mobile X-ray units in Lima, Peru: a RE-AIM evaluation. | Yuen CM, Puma D, Millones AK, Galea JT, Tzelios C, Calderon RI, Brooks MB, Jimenez J, Contreras C, Nichols TC, Nicholson T, Lecca L, Becerra MC, Keshavjee S | BMJ open | 34234000 | BMJ Open | 2021 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/34234000 |
Geospatial analysis of reported activity locations to identify sites for tuberculosis screening. | Yuen CM, Brooks MB, Millones AK, Acosta D, Del Águila-Rojas E, Campos H, Farroñay S, Morales G, Ramirez-Sandoval J, Nichols TC, Jimenez J, Jenkins HE, Lecca L | Scientific reports | 35982104 | Sci Rep | 2022 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/35982104 |
A role for community-level socioeconomic indicators in targeting tuberculosis screening interventions. | Brooks MB, Jenkins HE, Puma D, Tzelios C, Millones AK, Jimenez J, Galea JT, Lecca L, Becerra MC, Keshavjee S, Yuen CM | Scientific reports | 35039612 | Sci Rep | 2022 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/35039612 |
Adapting a mobile TB screening unit to provide integrated screening services and linkage to primary care. | Millones AK, Cohen S, Acosta D, Campos H, Condeso A, Farroñay S, Torres I, Vargas C, Abanto K, Contreras C, Palomino S, Jimenez J, Lecca L, Yuen CM | Public health action | 39618835 | Public Health Action | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39618835 |
Person-centered strategies for delivering TB diagnostic services in Lima, Peru. | Yuen CM, Millones AK, Acosta D, Torres I, Farroñay S, Jimenez J, Lecca L | Public health action | 37736576 | Public Health Action | 2023 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/37736576 |
Exploring the role of the private sector in tuberculosis detection and management in Lima, Peru: a mixed-methods patient pathway analysis. | Wippel C, Farroñay S, Gilbert HN, Millones AK, Acosta D, Torres I, Jimenez J, Lecca L, Yuen CM | medRxiv : the preprint server for health sciences | 37808756 | medRxiv | 2023 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/37808756 |
Geographic accessibility to health facilities predicts uptake of community-based tuberculosis screening in an urban setting. | Jenkins HE, Ayuk S, Puma D, Brooks MB, Millones AK, Jimenez J, Lecca L, Galea JT, Becerra M, Keshavjee S, Yuen CM | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases | 35470023 | Int J Infect Dis | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35470023 |
Utility of Mycobacterium tuberculosis Genome Sequencing Snapshots to Assess Transmission Dynamics Over Time. | Yuen CM, Huang CC, Millones AK, Calderon RI, Manson AL, Jimenez J, Contreras C, Earl AM, Becerra MC, Lecca L, Murray MB | The Journal of infectious diseases | 37995298 | J Infect Dis | 2024 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/37995298 |
Impact of the private sector on spatial accessibility to chest radiography services in Lima, Peru. | Xiong Y, Millones AK, Farroñay S, Torres I, Acosta D, Jordan DR, Jimenez J, Wippel C, Jenkins HE, Lecca L, Yuen CM | IJTLD open | 38698907 | IJTLD Open | 2024 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/38698907 |
Barriers and facilitators to tuberculosis diagnosis in Lima, Peru: a mixed methods study. | Geadas C, Millones AK, Acosta D, Campos H, Del Aguila-Rojas E, Farroñay S, Morales G, Ramirez-Sandoval J, Torres I, Jimenez J, Lecca L, Yuen CM | BMC infectious diseases | 39118040 | BMC Infect Dis | 2024 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/39118040 |
Mapping local hot spots with routine tuberculosis data: A pragmatic approach to identify spatial variability. | Brooks MB, Millones AK, Puma D, Contreras C, Jimenez J, Tzelios C, Jenkins HE, Yuen CM, Keshavjee S, Lecca L, Becerra MC | PloS one | 35324987 | PLoS One | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35324987 |
Closing delivery gaps in the treatment of tuberculosis infection: Lessons from implementation research in Peru. | Yuen CM, Millones AK, Puma D, Jimenez J, Galea JT, Calderon R, Pages GS, Brooks MB, Lecca L, Nicholson T, Becerra MC, Keshavjee S | PloS one | 33606824 | PLoS One | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33606824 |
Toward patient-centered tuberculosis preventive treatment: preferences for regimens and formulations in Lima, Peru. | Yuen CM, Millones AK, Galea JT, Puma D, Jimenez J, Lecca L, Becerra MC, Keshavjee S | BMC public health | 33430823 | BMC Public Health | 2021 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/33430823 |
Exploring the Role of the Private Sector in Tuberculosis Detection and Management in Lima, Peru: A Mixed-Methods Patient Pathway Analysis. | Wippel C, Farroñay S, Gilbert HN, Millones AK, Acosta D, Torres I, Jimenez J, Alarcón VA, Lecca L, Yuen CM | The American journal of tropical medicine and hygiene | 38744270 | Am J Trop Med Hyg | 2024 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/38744270 |
Preventive parenting intervention during childhood and young black adults' unhealthful behaviors: a randomized controlled trial. | Brody GH, Yu T, Miller GE, Ehrlich KB, Chen E | Journal of child psychology and psychiatry, and allied disciplines | 30203840 | J Child Psychol Psychiatry | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30203840 |
Attachment and psychoneuroimmunology. | Ehrlich KB | Current opinion in psychology | 29631123 | Curr Opin Psychol | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29631123 |
Maltreatment exposure across childhood and low-grade inflammation: Considerations of exposure type, timing, and sex differences. | Ehrlich KB, Miller GE, Rogosch FA, Cicchetti D | Developmental psychobiology | 32896910 | Dev Psychobiol | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32896910 |
Beyond Early Adversity: The Role of Parenting in Infant Physical Health. | Stern JA, Beijers R, Ehrlich KB, Cassidy J, de Weerth C | Journal of developmental and behavioral pediatrics : JDBP | 32271266 | J Dev Behav Pediatr | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32271266 |
Emotional Distress, Targeted Rejection, and Antibody Production After Influenza Vaccination in Adolescence. | Corallo KL, Lyle SM, Carlock MA, Ross TM, Ehrlich KB | Psychosomatic medicine | 35100185 | Psychosom Med | 2022 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/35100185 |
A preliminary investigation of attachment style and inflammation in African-American young adults. | Ehrlich KB, Stern JA, Eccles J, Dinh JV, Hopper EA, Kemeny ME, Adam EK, Cassidy J | Attachment & human development | 30406721 | Attach Hum Dev | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30406721 |
Exposure to parental depression in adolescence and proinflammatory phenotypes 20 years later. | Ehrlich KB, Celia-Sanchez ML, Yu T, Heard-Garris N, Chen E, Miller GE, Brody GH | Brain, behavior, and immunity | 38242368 | Brain Behav Immun | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38242368 |
How does the social world shape health across the lifespan? Insights and new directions. | Ehrlich KB | The American psychologist | 33382288 | Am Psychol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33382288 |
The Profundity of the Everyday: Family Routines in Adolescence Predict Development in Young Adulthood. | Barton AW, Brody GH, Yu T, Kogan SM, Chen E, Ehrlich KB | The Journal of adolescent health : official publication of the Society for Adolescent Medicine | 30392861 | J Adolesc Health | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30392861 |
Recalled Neighborhood Environments, Parental Control, and Cytokine-Mediated Response to Viral Challenge. | Corallo KL, Lyle SM, Murphy MLM, vanDellen MR, Ehrlich KB | Psychosomatic medicine | 34334728 | Psychosom Med | 2021 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/34334728 |
Neighborhood poverty, allostatic load, and changes in cellular aging in African American young adults: the moderating role of attachment. | Ehrlich KB, Yu T, Sadiq A, Brody GH | Attachment & human development | 34617499 | Attach Hum Dev | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34617499 |
Changes in depressive symptoms and antibody production following influenza vaccination in adolescents and adults. | Ehrlich KB, Lyle SM, Corallo KL, Lavner JA, Ross TM | Vaccine | 38702230 | Vaccine | 2024 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/38702230 |
The protective role of parental vigilance in the link between risky childhood environments and health. | Corallo KL, Carr CP, Lavner JA, Koss KJ, Ehrlich KB | Social science & medicine (1982) | 36527897 | Soc Sci Med | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36527897 |
Attachment and physical health: introduction to the special issue. | B Ehrlich K, Cassidy J | Attachment & human development | 30406722 | Attach Hum Dev | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30406722 |
Harsh parenting and youth systemic inflammation: Modulation by the autonomic nervous system. | Oshri A, Duprey EB, Liu S, Ehrlich KB | Health psychology : official journal of the Division of Health Psychology, American Psychological Association | 32202827 | Health Psychol | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32202827 |
Socioeconomic disadvantage and high-effort coping in childhood: evidence of skin-deep resilience. | Ehrlich KB, Lyle SM, Corallo KL, Brisson JM, Wiggins ER, Yu T, Chen E, Miller GE, Brody GH | Journal of child psychology and psychiatry, and allied disciplines | 37246563 | J Child Psychol Psychiatry | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/37246563 |
The benefits of nurturant-involved parenting for children's internalizing symptoms and cardiometabolic health in high-risk contexts. | Wiggins ER, Brisson JM, Lavner JA, Ehrlich KB | Development and psychopathology | 37386849 | Dev Psychopathol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37386849 |
CAUSAL INFERENCE IN THE CONTEXT OF AN ERROR PRONE EXPOSURE: AIR POLLUTION AND MORTALITY. | Wu X, Braun D, Kioumourtzoglou MA, Choirat C, Di Q, Dominici F | The annals of applied statistics | 31649797 | Ann Appl Stat | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31649797 |
Machine Learning for Prediction in Electronic Health Data. | Rose S | JAMA network open | 30646089 | JAMA Netw Open | 2018 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/30646089 |
Intersections of machine learning and epidemiological methods for health services research. | Rose S | International journal of epidemiology | 32236476 | Int J Epidemiol | 2021 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/32236476 |
High-Dimensional Confounding Adjustment Using Continuous Spike and Slab Priors. | Antonelli J, Parmigiani G, Dominici F | Bayesian analysis | 32431779 | Bayesian Anal | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32431779 |
Considerations Across Three Cultures: Parametric Regressions, Interpretable Algorithms, and Complex Algorithms. | Eloyan A, Rose S | Observational studies | 34485997 | Obs Stud | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34485997 |
Fair regression for health care spending. | Zink A, Rose S | Biometrics | 31860120 | Biometrics | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31860120 |
Identifying undercompensated groups defined by multiple attributes in risk adjustment. | Zink A, Rose S | BMJ health & care informatics | 34535447 | BMJ Health Care Inform | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34535447 |
Reflection on modern methods: when worlds collide-prediction, machine learning and causal inference. | Blakely T, Lynch J, Simons K, Bentley R, Rose S | International journal of epidemiology | 31298274 | Int J Epidemiol | 2021 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/31298274 |
Air pollution exposure disparities across US population and income groups. | Jbaily A, Zhou X, Liu J, Lee TH, Kamareddine L, Verguet S, Dominici F | Nature | 35022594 | Nature | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/35022594 |
Conditional cross-design synthesis estimators for generalizability in Medicaid. | Degtiar I, Layton T, Wallace J, Rose S | Biometrics | 37018228 | Biometrics | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37018228 |
Evaluation of the health impacts of the 1990 Clean Air Act Amendments using causal inference and machine learning. | Nethery RC, Mealli F, Sacks JD, Dominici F | Journal of the American Statistical Association | 33424062 | J Am Stat Assoc | 2020 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/33424062 |
Causal inference in high dimensions: A marriage between Bayesian modeling and good frequentist properties. | Antonelli J, Papadogeorgou G, Dominici F | Biometrics | 33349923 | Biometrics | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33349923 |
Considerations for outcome-dependent biased sampling in health databases. | Rose S | Statistics in medicine | 31489684 | Stat Med | 2019 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/31489684 |
Measuring concordance of data sources used for infectious disease research in the USA: a retrospective data analysis. | Majumder MS, Cusick M, Rose S | BMJ open | 36854597 | BMJ Open | 2023 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/36854597 |
All Models are Wrong, but Many are Useful: Learning a Variable's Importance by Studying an Entire Class of Prediction Models Simultaneously. | Fisher A, Rudin C, Dominici F | Journal of machine learning research : JMLR | 34335110 | J Mach Learn Res | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/34335110 |
Uncertainty in lung cancer stage for survival estimation via set-valued classification. | Bergquist S, Brooks GA, Landrum MB, Keating NL, Rose S | Statistics in medicine | 35675972 | Stat Med | 2022 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/35675972 |
Discovering Heterogeneous Exposure Effects Using Randomization Inference in Air Pollution Studies. | Lee K, Small DS, Dominici F | Journal of the American Statistical Association | 36311902 | J Am Stat Assoc | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/36311902 |
Data Source Concordance for Infectious Disease Epidemiology. | Majumder M, Cusick MM, Rose S | medRxiv : the preprint server for health sciences | 35677068 | medRxiv | 2022 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/35677068 |
Limitations of P-Values and R-squared for Stepwise Regression Building: A Fairness Demonstration in Health Policy Risk Adjustment. | Rose S, McGuire TG | The American statistician | 31263291 | Am Stat | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31263291 |
A causal inference framework for cancer cluster investigations using publicly available data. | Nethery RC, Yang Y, Brown AJ, Dominici F | Journal of the Royal Statistical Society. Series A, (Statistics in Society) | 34262243 | J R Stat Soc Ser A Stat Soc | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34262243 |
Ethical Machine Learning in Healthcare. | Chen IY, Pierson E, Rose S, Joshi S, Ferryman K, Ghassemi M | Annual review of biomedical data science | 34396058 | Annu Rev Biomed Data Sci | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34396058 |
A generalizable data assembly algorithm for infectious disease outbreaks. | Majumder MS, Rose S | JAMIA open | 34350393 | JAMIA Open | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34350393 |
Improving the Performance of Risk Adjustment Systems: Constrained Regressions, Reinsurance, and Variable Selection. | McGuire TG, Zink AL, Rose S | American journal of health economics | 34869790 | Am J Health Econ | 2021 Fall | https://www.ncbi.nlm.nih.gov/pubmed/34869790 |
Discussion on "Approval policies for modifications to machine learning-based software as a medical device: A study of biocreep" by Jean Feng, Scott Emerson, and Noah Simon. | Rose S | Biometrics | 33040334 | Biometrics | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33040334 |
Evaluating Federal Policies Using Bayesian Time Series Models: Estimating the Causal Impact of the Hospital Readmissions Reduction Program. | Papadogeorgou G, Menchetti F, Choirat C, Wasfy JH, Zigler CM, Mealli F | Health services & outcomes research methodology | 39866244 | Health Serv Outcomes Res Methodol | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39866244 |
Evaluating the Health Impact of Large-Scale Public Policy Changes: Classical and Novel Approaches. | Basu S, Meghani A, Siddiqi A | Annual review of public health | 28384086 | Annu Rev Public Health | 2017 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/28384086 |
Food Insecurity and Health Care Expenditures in the United States, 2011-2013. | Berkowitz SA, Basu S, Meigs JB, Seligman HK | Health services research | 28608473 | Health Serv Res | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28608473 |
Preventing false discovery of heterogeneous treatment effect subgroups in randomized trials. | Rigdon J, Baiocchi M, Basu S | Trials | 30012181 | Trials | 2018 Jul 16 | https://www.ncbi.nlm.nih.gov/pubmed/30012181 |
Mother's education and late-life disparities in memory and dementia risk among US military veterans and non-veterans. | Vable AM, Eng CW, Mayeda ER, Basu S, Marden JR, Hamad R, Glymour MM | Journal of epidemiology and community health | 30082424 | J Epidemiol Community Health | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30082424 |
Performance of Matching Methods as Compared With Unmatched Ordinary Least Squares Regression Under Constant Effects. | Vable AM, Kiang MV, Glymour MM, Rigdon J, Drabo EF, Basu S | American journal of epidemiology | 30995301 | Am J Epidemiol | 2019 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/30995301 |
Evaluating strategies for control of tuberculosis in prisons and prevention of spillover into communities: An observational and modeling study from Brazil. | Mabud TS, de Lourdes Delgado Alves M, Ko AI, Basu S, Walter KS, Cohen T, Mathema B, Colijn C, Lemos E, Croda J, Andrews JR | PLoS medicine | 30677013 | PLoS Med | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30677013 |
Re-evaluating associations between the Supplemental Nutrition Assistance Program participation and body mass index in the context of unmeasured confounders. | Rigdon J, Berkowitz SA, Seligman HK, Basu S | Social science & medicine (1982) | 28965002 | Soc Sci Med | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28965002 |
Near-Far Matching in R: The nearfar Package. | Rigdon J, Baiocchi M, Basu S | Journal of statistical software | 30386186 | J Stat Softw | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30386186 |
Health and Economic Implications of National Treatment Coverage for Cardiovascular Disease in India: Cost-Effectiveness Analysis. | Basu S, Bendavid E, Sood N | Circulation. Cardiovascular quality and outcomes | 26555122 | Circ Cardiovasc Qual Outcomes | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26555122 |
Impact of the North American Free Trade Agreement on high-fructose corn syrup supply in Canada: a natural experiment using synthetic control methods. | Barlow P, McKee M, Basu S, Stuckler D | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | 28676578 | CMAJ | 2017 Jul 4 | https://www.ncbi.nlm.nih.gov/pubmed/28676578 |
Dynamic treatment selection and modification for personalised blood pressure therapy using a Markov decision process model: a cost-effectiveness analysis. | Choi SE, Brandeau ML, Basu S | BMJ open | 29146652 | BMJ Open | 2017 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/29146652 |
BOUNDS ON THE CONDITIONAL AND AVERAGE TREATMENT EFFECT WITH UNOBSERVED CONFOUNDING FACTORS. | Yadlowsky S, Namkoong H, Basu S, Duchi J, Tian L | Annals of statistics | 38050638 | Ann Stat | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38050638 |
Supplemental Nutrition Assistance Program (SNAP) Participation and Health Care Expenditures Among Low-Income Adults. | Berkowitz SA, Seligman HK, Rigdon J, Meigs JB, Basu S | JAMA internal medicine | 28973507 | JAMA Intern Med | 2017 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/28973507 |
Estimating the long-run relationship between state cigarette taxes and county life expectancy. | Baum A, Aguilar-Gomez S, Lightwood J, Bruzelius E, Glantz SA, Basu S | Tobacco control | 30705247 | Tob Control | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30705247 |
Huntington's disease in the United States: Variation by demographic and socioeconomic factors. | Bruzelius E, Scarpa J, Zhao Y, Basu S, Faghmous JH, Baum A | Movement disorders : official journal of the Movement Disorder Society | 30868663 | Mov Disord | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30868663 |
Opioid prescribing patterns among medical providers in the United States, 2003-17: retrospective, observational study. | Kiang MV, Humphreys K, Cullen MR, Basu S | BMJ (Clinical research ed.) | 31996352 | BMJ | 2020 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/31996352 |
Personalizing Medical Treatment Decisions: Integrating Meta-analytic Treatment Comparisons with Patient-Specific Risks and Preferences. | Weyant C, Brandeau ML, Basu S | Medical decision making : an international journal of the Society for Medical Decision Making | 31707910 | Med Decis Making | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31707910 |
Basu et al. Respond to "Interdisciplinary Approach for Policy Evaluation". | Basu S, Rehkopf DH, Siddiqi A, Glymour MM, Kawachi I | American journal of epidemiology | 26946397 | Am J Epidemiol | 2016 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/26946397 |
Machine Learning Methods for Precision Medicine Research Designed to Reduce Health Disparities: A Structured Tutorial. | Basu S, Faghmous JH, Doupe P | Ethnicity & disease | 32269464 | Ethn Dis | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32269464 |
Detecting Anomalies Among Practice Sites Within Multicenter Trials. | Berkowitz SA, Rudolph KE, Basu S | Circulation. Cardiovascular quality and outcomes | 30857413 | Circ Cardiovasc Qual Outcomes | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30857413 |
Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis. | Berkowitz SA, Basu S, Venkataramani A, Reznor G, Fleegler EW, Atlas SJ | BMJ open | 30862634 | BMJ Open | 2019 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/30862634 |
Food insecurity, healthcare utilization, and high cost: a longitudinal cohort study. | Berkowitz SA, Seligman HK, Meigs JB, Basu S | The American journal of managed care | 30222918 | Am J Manag Care | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30222918 |
Generalizing Intensive Blood Pressure Treatment to Adults With Diabetes Mellitus. | Berkowitz SA, Sussman JB, Jonas DE, Basu S | Journal of the American College of Cardiology | 30189998 | J Am Coll Cardiol | 2018 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/30189998 |
Moderation of the Relation of County-Level Cost of Living to Nutrition by the Supplemental Nutrition Assistance Program. | Basu S, Wimer C, Seligman H | American journal of public health | 27631742 | Am J Public Health | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27631742 |
Development and validation of Risk Equations for Complications Of type 2 Diabetes (RECODe) using individual participant data from randomised trials. | Basu S, Sussman JB, Berkowitz SA, Hayward RA, Yudkin JS | The lancet. Diabetes & endocrinology | 28803840 | Lancet Diabetes Endocrinol | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28803840 |
Targeting weight loss interventions to reduce cardiovascular complications of type 2 diabetes: a machine learning-based post-hoc analysis of heterogeneous treatment effects in the Look AHEAD trial. | Baum A, Scarpa J, Bruzelius E, Tamler R, Basu S, Faghmous J | The lancet. Diabetes & endocrinology | 28711469 | Lancet Diabetes Endocrinol | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28711469 |
Long-term effects of neighbourhood deprivation on diabetes risk: quasi-experimental evidence from a refugee dispersal policy in Sweden. | White JS, Hamad R, Li X, Basu S, Ohlsson H, Sundquist J, Sundquist K | The lancet. Diabetes & endocrinology | 27131930 | Lancet Diabetes Endocrinol | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27131930 |
Assessment of Changes in the Geographical Distribution of Opioid-Related Mortality Across the United States by Opioid Type, 1999-2016. | Kiang MV, Basu S, Chen J, Alexander MJ | JAMA network open | 30794299 | JAMA Netw Open | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30794299 |
Machine learning with sparse nutrition data to improve cardiovascular mortality risk prediction in the USA using nationally randomly sampled data. | Rigdon J, Basu S | BMJ open | 31784446 | BMJ Open | 2019 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/31784446 |
Matching Microsimulation Risk Factor Correlations to Cross-sectional Data: The Shortest Distance Method. | Suen SC, Goldhaber-Fiebert JD, Basu S | Medical decision making : an international journal of the Society for Medical Decision Making | 29185378 | Med Decis Making | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29185378 |
Health Behaviors, Mental Health, and Health Care Utilization Among Single Mothers After Welfare Reforms in the 1990s. | Basu S, Rehkopf DH, Siddiqi A, Glymour MM, Kawachi I | American journal of epidemiology | 26946395 | Am J Epidemiol | 2016 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/26946395 |
Comparative effectiveness and cost-effectiveness of treat-to-target versus benefit-based tailored treatment of type 2 diabetes in low-income and middle-income countries: a modelling analysis. | Basu S, Shankar V, Yudkin JS | The lancet. Diabetes & endocrinology | 27717768 | Lancet Diabetes Endocrinol | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27717768 |
Validation of Risk Equations for Complications of Type 2 Diabetes (RECODe) Using Individual Participant Data From Diverse Longitudinal Cohorts in the U.S. | Basu S, Sussman JB, Berkowitz SA, Hayward RA, Bertoni AG, Correa A, Mwasongwe S, Yudkin JS | Diabetes care | 29269511 | Diabetes Care | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29269511 |
Characteristics Associated With Decreased or Increased Mortality Risk From Glycemic Therapy Among Patients With Type 2 Diabetes and High Cardiovascular Risk: Machine Learning Analysis of the ACCORD Trial. | Basu S, Raghavan S, Wexler DJ, Berkowitz SA | Diabetes care | 29279299 | Diabetes Care | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29279299 |
Decomposition of the US black/white inequality in premature mortality, 2010-2015: an observational study. | Kiang MV, Krieger N, Buckee CO, Onnela JP, Chen JT | BMJ open | 31748287 | BMJ Open | 2019 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/31748287 |
Cost Effectiveness of Subsidizing Fruit and Vegetable Purchases Through the Supplemental Nutrition Assistance Program. | Choi SE, Seligman H, Basu S | American journal of preventive medicine | 28153648 | Am J Prev Med | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28153648 |
Anticipated burden and mitigation of carbon-dioxide-induced nutritional deficiencies and related diseases: A simulation modeling study. | Weyant C, Brandeau ML, Burke M, Lobell DB, Bendavid E, Basu S | PLoS medicine | 29969442 | PLoS Med | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29969442 |
Benefit and harm of intensive blood pressure treatment: Derivation and validation of risk models using data from the SPRINT and ACCORD trials. | Basu S, Sussman JB, Rigdon J, Steimle L, Denton BT, Hayward RA | PLoS medicine | 29040268 | PLoS Med | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29040268 |
Machine Learning for Health Services Researchers. | Doupe P, Faghmous J, Basu S | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research | 31277828 | Value Health | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31277828 |
Personalizing Second-Line Type 2 Diabetes Treatment Selection: Combining Network Meta-analysis, Individualized Risk, and Patient Preferences for Unified Decision Support. | Choi SE, Berkowitz SA, Yudkin JS, Naci H, Basu S | Medical decision making : an international journal of the Society for Medical Decision Making | 30767632 | Med Decis Making | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30767632 |
Black-White Cardiovascular Disease Disparities After Target-Based Versus Personalized Benefit-Based Lipid and Blood Pressure Treatment. | Basu S, Sussman JB, Hayward RA | MDM policy & practice | 30288429 | MDM Policy Pract | 2017 Jul-Dec | https://www.ncbi.nlm.nih.gov/pubmed/30288429 |
Association of Primary Care Physician Supply With Population Mortality in the United States, 2005-2015. | Basu S, Berkowitz SA, Phillips RL, Bitton A, Landon BE, Phillips RS | JAMA internal medicine | 30776056 | JAMA Intern Med | 2019 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/30776056 |
Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk. | Yadlowsky S, Hayward RA, Sussman JB, McClelland RL, Min YI, Basu S | Annals of internal medicine | 29868850 | Ann Intern Med | 2018 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/29868850 |
Are There Spillover Effects from the GI Bill? The Mental Health of Wives of Korean War Veterans. | Vable AM, Kawachi I, Canning D, Glymour MM, Jimenez MP, Subramanian SV | PloS one | 27186983 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27186983 |
Alternative Strategies to Achieve Cardiovascular Mortality Goals in China and India: A Microsimulation of Target- Versus Risk-Based Blood Pressure Treatment. | Basu S, Yudkin JS, Sussman JB, Millett C, Hayward RA | Circulation | 26762520 | Circulation | 2016 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26762520 |
The Monthly Cycle of Hypoglycemia: An Observational Claims-based Study of Emergency Room Visits, Hospital Admissions, and Costs in a Commercially Insured Population. | Basu S, Berkowitz SA, Seligman H | Medical care | 28481762 | Med Care | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28481762 |
Detecting Heterogeneous Treatment Effects to Guide Personalized Blood Pressure Treatment: A Modeling Study of Randomized Clinical Trials. | Basu S, Sussman JB, Hayward RA | Annals of internal medicine | 28055048 | Ann Intern Med | 2017 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/28055048 |
Illustrating a "consequential" shift in the study of health inequalities: a decomposition of racial differences in the distribution of body mass. | Siddiqi A, Shahidi FV, Hildebrand V, Hong A, Basu S | Annals of epidemiology | 29576050 | Ann Epidemiol | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29576050 |
A New Tool for Case Studies in Epidemiology-the Synthetic Control Method. | Rehkopf DH, Basu S | Epidemiology (Cambridge, Mass.) | 29613871 | Epidemiology | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29613871 |
Military Service, Childhood Socio-Economic Status, and Late-Life Lung Function: Korean War Era Military Service Associated with Smaller Disparities. | Vable AM, Kiang MV, Basu S, Rudolph KE, Kawachi I, Subramanian SV, Glymour MM | Military medicine | 29509934 | Mil Med | 2018 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/29509934 |
DiracDiffusion: Denoising and Incremental Reconstruction with Assured Data-Consistency. | Fabian Z, Tinaz B, Soltanolkotabi M | Proceedings of machine learning research | 39416230 | Proc Mach Learn Res | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/39416230 |
Adapt and Diffuse: Sample-Adaptive Reconstruction Via Latent Diffusion Models. | Fabian Z, Tinaz B, Soltanolkotabi M | Proceedings of machine learning research | 39318400 | Proc Mach Learn Res | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/39318400 |
Provable Multi-Task Representation Learning by Two-Layer ReLU Neural Networks. | Collins L, Hassani H, Soltanolkotabi M, Mokhtari A, Shakkottai S | Proceedings of machine learning research | 39421278 | Proc Mach Learn Res | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/39421278 |
Gradient Descent Provably Solves Nonlinear Tomographic Reconstruction. | Fridovich-Keil S, Valdivia F, Wetzstein G, Recht B, Soltanolkotabi M | ArXiv | 37873016 | ArXiv | 2023 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/37873016 |
Human-in-the-Loop Optimization for Deep Stimulus Encoding in Visual Prostheses. | Granley J, Fauvel T, Chalk M, Beyeler M | Advances in neural information processing systems | 38984104 | Adv Neural Inf Process Syst | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/38984104 |
Efficient Spatial Estimation of Perceptual Thresholds for Retinal Implants via Gaussian Process Regression. | Sadeghi R, Beyeler M | ArXiv | 39990794 | ArXiv | 2025 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/39990794 |
Towards aSmart Bionic Eye: AI-powered artificial vision for the treatment of incurable blindness. | Beyeler M, Sanchez-Garcia M | Journal of neural engineering | 36541463 | J Neural Eng | 2022 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/36541463 |
Aligning Visual Prosthetic Development With Implantee Needs. | Nadolskis L, Turkstra LM, Larnyo E, Beyeler M | Translational vision science & technology | 39570616 | Transl Vis Sci Technol | 2024 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/39570616 |
Aligning visual prosthetic development with implantee needs. | Nadolskis LG, Turkstra LM, Larnyo E, Beyeler M | medRxiv : the preprint server for health sciences | 38559196 | medRxiv | 2024 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/38559196 |
A systematic review of extended reality (XR) for understanding and augmenting vision loss. | Kasowski J, Johnson BA, Neydavood R, Akkaraju A, Beyeler M | Journal of vision | 37140911 | J Vis | 2023 May 2 | https://www.ncbi.nlm.nih.gov/pubmed/37140911 |
The Relative Importance of Depth Cues and Semantic Edges for Indoor Mobility Using Simulated Prosthetic Vision in Immersive Virtual Reality. | Rasla A, Beyeler M | Proceedings of the ACM Symposium on Virtual Reality Software and Technology. ACM Symposium on Virtual Reality Software and Technology | 40017497 | Proc ACM Symp Virtual Real Softw Technol | 2022 Nov-Dec | https://www.ncbi.nlm.nih.gov/pubmed/40017497 |
Causal isotonic calibration for heterogeneous treatment effects. | van der Laan L, Ulloa-Pérez E, Carone M, Luedtke A | Proceedings of machine learning research | 37575467 | Proc Mach Learn Res | 2023 Jul | https://www.ncbi.nlm.nih.gov/pubmed/37575467 |
Improving precision and power in randomized trials for COVID-19 treatments using covariate adjustment, for binary, ordinal, and time-to-event outcomes. | Benkeser D, Díaz I, Luedtke A, Segal J, Scharfstein D, Rosenblum M | Biometrics | 32978962 | Biometrics | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32978962 |
Correction to: "Optimal Individualized Decision Rules Using Instrumental Variable Methods". | Qiu H, Carone M, Sadikova E, Petukhova M, Kessler RC, Luedtke A | Journal of the American Statistical Association | 35756162 | J Am Stat Assoc | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/35756162 |
Improved efficiency for cross-arm comparisons via platform designs. | Huang TJ, Luedtke A, AMP INVESTIGATOR GROUP | Biostatistics (Oxford, England) | 35939566 | Biostatistics | 2023 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/35939566 |
Improved inference for vaccine-induced immune responses via shape-constrained methods. | Laha N, Moodie Z, Huang Y, Luedtke A | Electronic journal of statistics | 37974631 | Electron J Stat | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/37974631 |
Inference for treatment-specific survival curves using machine learning. | Westling T, Luedtke A, Gilbert PB, Carone M | Journal of the American Statistical Association | 39184837 | J Am Stat Assoc | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/39184837 |
Optimal individualized decision rules using instrumental variable methods. | Qiu H, Carone M, Sadikova E, Petukhova M, Kessler RC, Luedtke A | Journal of the American Statistical Association | 33731969 | J Am Stat Assoc | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33731969 |
Universal sieve-based strategies for efficient estimation using machine learning tools. | Qiu H, Luedtke A, Carone M | Bernoulli : official journal of the Bernoulli Society for Mathematical Statistics and Probability | 34733110 | Bernoulli (Andover) | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34733110 |
Discussion on "Estimating vaccine efficacy over time after a randomized study is unblinded" by Anastasios A. Tsiatis and Marie Davidian. | Janes H, Gao F, Luedtke A | Biometrics | 34492117 | Biometrics | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34492117 |
Performance Guarantees for Policy Learning. | Luedtke A, Chambaz A | Annales de l'I.H.P. Probabilites et statistiques | 35321441 | Ann I H P Probab Stat | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35321441 |
Discussion of and : New Objectives for Policy Learning. | Li S, Li X, Luedtke A | Journal of the American Statistical Association | 36910906 | J Am Stat Assoc | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/36910906 |
Adversarial Monte Carlo Meta-Learning of Optimal Prediction Procedures. | Luedtke A, Chung I, Sofrygin O | Journal of machine learning research : JMLR | 38476310 | J Mach Learn Res | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/38476310 |
Rejoinder: Improving precision and power in randomized trials for COVID-19 treatments using covariate adjustment, for binary, ordinal, and time-to-event outcomes. | Benkeser D, Díaz I, Luedtke A, Segal J, Scharfstein D, Rosenblum M | Biometrics | 34050931 | Biometrics | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34050931 |
Re. Selecting Optimal Subgroups for Treatment Using Many Covariates. | Penning de Vries BBL, Groenwold RHH, Luedtke A | Epidemiology (Cambridge, Mass.) | 32282408 | Epidemiology | 2020 Jul | https://www.ncbi.nlm.nih.gov/pubmed/32282408 |
Estimating the Efficiency Gain of Covariate-Adjusted Analyses in Future Clinical Trials Using External Data. | Li X, Li S, Luedtke A | Journal of the Royal Statistical Society. Series B, Statistical methodology | 37593690 | J R Stat Soc Series B Stat Methodol | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37593690 |
Efficient Estimation under Data Fusion. | Li S, Luedtke A | Biometrika | 37982010 | Biometrika | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37982010 |
EFFICIENT ESTIMATION OF THE MAXIMAL ASSOCIATION BETWEEN MULTIPLE PREDICTORS AND A SURVIVAL OUTCOME. | Huang TJ, Luedtke A, McKeague IW | Annals of statistics | 38405375 | Ann Stat | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38405375 |
Adversarial meta-learning of Gamma-minimax estimators that leverage prior knowledge. | Qiu H, Luedtke A | Electronic journal of statistics | 38463692 | Electron J Stat | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/38463692 |
Improving Precision and Power in Randomized Trials for COVID-19 Treatments Using Covariate Adjustment, for Binary, Ordinal, and Time-to-Event Outcomes. | Benkeser D, Díaz I, Luedtke A, Segal J, Scharfstein D, Rosenblum M | medRxiv : the preprint server for health sciences | 32577668 | medRxiv | 2020 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/32577668 |
Rejoinder: Optimal individualized decision rules using instrumental variable methods. | Qiu H, Carone M, Sadikova E, Petukhova M, Kessler RC, Luedtke A | Journal of the American Statistical Association | 36092993 | J Am Stat Assoc | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/36092993 |
A Mixture Model for Estimating SARS-CoV-2 Seroprevalence in Chennai, India. | Hitchings MDT, Patel EU, Khan R, Srikrishnan AK, Anderson M, Kumar KS, Wesolowski AP, Iqbal SH, Rodgers MA, Mehta SH, Cloherty G, Cummings DAT, Solomon SS | American journal of epidemiology | 37084085 | Am J Epidemiol | 2023 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/37084085 |
Trip duration drives shift in travel network structure with implications for the predictability of spatial disease spread. | Giles JR, Cummings DAT, Grenfell BT, Tatem AJ, Erbach-Schoenberg EZ, Metcalf C, Wesolowski A | PLoS computational biology | 34375331 | PLoS Comput Biol | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34375331 |
A systematic review of antibody mediated immunity to coronaviruses: antibody kinetics, correlates of protection, and association of antibody responses with severity of disease. | Huang AT, Garcia-Carreras B, Hitchings MDT, Yang B, Katzelnick LC, Rattigan SM, Borgert BA, Moreno CA, Solomon BD, Rodriguez-Barraquer I, Lessler J, Salje H, Burke D, Wesolowski A, Cummings DAT | medRxiv : the preprint server for health sciences | 32511434 | medRxiv | 2020 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/32511434 |
Coexisting attractors in the context of cross-scale population dynamics: measles in London as a case study. | Becker AD, Zhou SH, Wesolowski A, Grenfell BT | Proceedings. Biological sciences | 32315586 | Proc Biol Sci | 2020 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/32315586 |
The duration of travel impacts the spatial dynamics of infectious diseases. | Giles JR, Zu Erbach-Schoenberg E, Tatem AJ, Gardner L, Bjørnstad ON, Metcalf CJE, Wesolowski A | Proceedings of the National Academy of Sciences of the United States of America | 32839329 | Proc Natl Acad Sci U S A | 2020 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/32839329 |
A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity. | Huang AT, Garcia-Carreras B, Hitchings MDT, Yang B, Katzelnick LC, Rattigan SM, Borgert BA, Moreno CA, Solomon BD, Trimmer-Smith L, Etienne V, Rodriguez-Barraquer I, Lessler J, Salje H, Burke DS, Wesolowski A, Cummings DAT | Nature communications | 32943637 | Nat Commun | 2020 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/32943637 |
A systematic review of using population-level human mobility data to understand SARS-CoV-2 transmission. | Kostandova N, Schluth C, Arambepola R, Atuhaire F, Bérubé S, Chin T, Cleary E, Cortes-Azuero O, García-Carreras B, Grantz KH, Hitchings MDT, Huang AT, Kishore N, Lai S, Larsen SL, Loisate S, Martinez P, Meredith HR, Purbey R, Ramiadantsoa T, Read J, Rice BL, Rosman L, Ruktanonchai N, Salje H, Schaber KL, Tatem AJ, Wang J, Cummings DAT, Wesolowski A | Nature communications | 39627231 | Nat Commun | 2024 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/39627231 |
Mapping malaria by combining parasite genomic and epidemiologic data. | Wesolowski A, Taylor AR, Chang HH, Verity R, Tessema S, Bailey JA, Alex Perkins T, Neafsey DE, Greenhouse B, Buckee CO | BMC medicine | 30333020 | BMC Med | 2018 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/30333020 |
Genetic Evidence of Focal Plasmodium falciparum Transmission in a Pre-elimination Setting in Southern Province, Zambia. | Pringle JC, Tessema S, Wesolowski A, Chen A, Murphy M, Carpi G, Shields TM, Hamapumbu H, Searle KM, Kobayashi T, Katowa B, Musonda M, Stevenson JC, Thuma PE, Greenhouse B, Moss WJ, Norris DE | The Journal of infectious diseases | 30445612 | J Infect Dis | 2019 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/30445612 |
Long-term dynamics of measles in London: Titrating the impact of wars, the 1918 pandemic, and vaccination. | Becker AD, Wesolowski A, Bjørnstad ON, Grenfell BT | PLoS computational biology | 31513578 | PLoS Comput Biol | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31513578 |
Aggregated mobility data could help fight COVID-19. | Buckee CO, Balsari S, Chan J, Crosas M, Dominici F, Gasser U, Grad YH, Grenfell B, Halloran ME, Kraemer MUG, Lipsitch M, Metcalf CJE, Meyers LA, Perkins TA, Santillana M, Scarpino SV, Viboud C, Wesolowski A, Schroeder A | Science (New York, N.Y.) | 32205458 | Science | 2020 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/32205458 |
SARS-CoV-2 Testing in Florida, Illinois, and Maryland: Access and Barriers. | Clipman SJ, Wesolowski A, Mehta SH, Agarwal S, Cobey SE, Cummings DAT, Gibson DG, Labrique AB, Kirk GD, Solomon SS | medRxiv : the preprint server for health sciences | 33398298 | medRxiv | 2020 Dec 24 | https://www.ncbi.nlm.nih.gov/pubmed/33398298 |
Development and dissemination of infectious disease dynamic transmission models during the COVID-19 pandemic: what can we learn from other pathogens and how can we move forward? | Becker AD, Grantz KH, Hegde ST, Bérubé S, Cummings DAT, Wesolowski A | The Lancet. Digital health | 33735068 | Lancet Digit Health | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33735068 |
Reconstructing unseen transmission events to infer dengue dynamics from viral sequences. | Salje H, Wesolowski A, Brown TS, Kiang MV, Berry IM, Lefrancq N, Fernandez S, Jarman RG, Ruchusatsawat K, Iamsirithaworn S, Vandepitte WP, Suntarattiwong P, Read JM, Klungthong C, Thaisomboonsuk B, Engø-Monsen K, Buckee C, Cauchemez S, Cummings DAT | Nature communications | 33753725 | Nat Commun | 2021 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/33753725 |
The Challenge of Achieving Immunity Through Multiple-Dose Vaccines in Madagascar. | Jones FK, Mensah K, Heraud JM, Randriatsarafara FM, Metcalf CJE, Wesolowski A | American journal of epidemiology | 34023892 | Am J Epidemiol | 2021 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/34023892 |
Epidemiology of Plasmodium falciparum Infections in a Semi-Arid Rural African Setting: Evidence from Reactive Case Detection in Northwestern Kenya. | Meredith HR, Wesolowski A, Menya D, Esimit D, Lokoel G, Kipkoech J, Freedman B, Lokemer S, Maragia J, Ambani G, Taylor SM, Prudhomme-O'Meara W, Obala AA | The American journal of tropical medicine and hygiene | 34339387 | Am J Trop Med Hyg | 2021 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/34339387 |
The use of mobile phone data to inform analysis of COVID-19 pandemic epidemiology. | Grantz KH, Meredith HR, Cummings DAT, Metcalf CJE, Grenfell BT, Giles JR, Mehta S, Solomon S, Labrique A, Kishore N, Buckee CO, Wesolowski A | Nature communications | 32999287 | Nat Commun | 2020 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/32999287 |
High Plasmodium falciparum genetic diversity and temporal stability despite control efforts in high transmission settings along the international border between Zambia and the Democratic Republic of the Congo. | Pringle JC, Wesolowski A, Berube S, Kobayashi T, Gebhardt ME, Mulenga M, Chaponda M, Bobanga T, Juliano JJ, Meshnick S, Moss WJ, Carpi G, Norris DE | Malaria journal | 31801548 | Malar J | 2019 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/31801548 |
Mapping imported malaria in Bangladesh using parasite genetic and human mobility data. | Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A, Uddin D, Zaman SI, Hossain MA, Faiz MA, Ghose A, Sayeed AA, Rahman MR, Islam A, Karim MJ, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Drury E, Gonçalves S, Kekre M, Dhorda M, Vongpromek R, Miotto O, Engø-Monsen K, Kwiatkowski D, Maude RJ, Buckee C | eLife | 30938289 | Elife | 2019 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/30938289 |
Existing human mobility data sources poorly predicted the spatial spread of SARS-CoV-2 in Madagascar. | Ramiadantsoa T, Metcalf CJE, Raherinandrasana AH, Randrianarisoa S, Rice BL, Wesolowski A, Randriatsarafara FM, Rasambainarivo F | Epidemics | 34915300 | Epidemics | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/34915300 |
Long-term effects of increased adoption of artemisinin combination therapies in Burkina Faso. | Zupko RJ, Nguyen TD, Somé AF, Tran TN, Gerardin J, Dudas P, Giang DDH, Tran KT, Wesolowski A, Ouédraogo JB, Boni MF | PLOS global public health | 36962300 | PLOS Glob Public Health | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36962300 |
Using parasite genetic and human mobility data to infer local and cross-border malaria connectivity in Southern Africa. | Tessema S, Wesolowski A, Chen A, Murphy M, Wilheim J, Mupiri AR, Ruktanonchai NW, Alegana VA, Tatem AJ, Tambo M, Didier B, Cohen JM, Bennett A, Sturrock HJ, Gosling R, Hsiang MS, Smith DL, Mumbengegwi DR, Smith JL, Greenhouse B | eLife | 30938286 | Elife | 2019 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/30938286 |
Seasonal gaps in measles vaccination coverage in Madagascar. | Mensah K, Heraud JM, Takahashi S, Winter AK, Metcalf CJE, Wesolowski A | Vaccine | 30940486 | Vaccine | 2019 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/30940486 |
Mapping the travel patterns of people with malaria in Bangladesh. | Sinha I, Sayeed AA, Uddin D, Wesolowski A, Zaman SI, Faiz MA, Ghose A, Rahman MR, Islam A, Karim MJ, Saha A, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Chang HH, Miotto O, Kwiatkowski D, Dondorp AM, Day NPJ, Hossain MA, Buckee C, Maude RJ | BMC medicine | 32127002 | BMC Med | 2020 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/32127002 |
Using models to shape measles control and elimination strategies in low- and middle-income countries: A review of recent applications. | Cutts FT, Dansereau E, Ferrari MJ, Hanson M, McCarthy KA, Metcalf CJE, Takahashi S, Tatem AJ, Thakkar N, Truelove S, Utazi E, Wesolowski A, Winter AK | Vaccine | 31787412 | Vaccine | 2020 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/31787412 |
Infectious disease in an era of global change. | Baker RE, Mahmud AS, Miller IF, Rajeev M, Rasambainarivo F, Rice BL, Takahashi S, Tatem AJ, Wagner CE, Wang LF, Wesolowski A, Metcalf CJE | Nature reviews. Microbiology | 34646006 | Nat Rev Microbiol | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/34646006 |
Holiday gatherings, mobility and SARS-CoV-2 transmission: results from 10 US states following Thanksgiving. | Mehta SH, Clipman SJ, Wesolowski A, Solomon SS | Scientific reports | 34462499 | Sci Rep | 2021 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/34462499 |
Who is missed in a community-based survey: Assessment and implications of biases due to incomplete sampling frame in a community-based serosurvey, Choma and Ndola Districts, Zambia, 2022. | Kostandova N, Mutembo S, Prosperi C, Mwansa FD, Nakazwe C, Namukoko H, Nachinga B, Chongwe G, Chilumba I, Matakala KH, Musukwa G, Hamahuwa M, Mufwambi W, Matoba J, Situtu K, Mutale I, Kong AC, Simulundu E, Ndubani P, Hasan AZ, Truelove SA, Winter AK, Carcelen AC, Lau B, Moss WJ, Wesolowski A | PLOS global public health | 38683820 | PLOS Glob Public Health | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38683820 |
Characterizing mobility patterns and malaria risk factors in semi-nomadic populations of Northern Kenya. | Meredith HR, Wesolowski A, Okoth D, Maraga L, Ambani G, Chepkwony T, Abel L, Kipkoech J, Lokoel G, Esimit D, Lokemer S, Maragia J, Prudhomme O'Meara W, Obala AA | PLOS global public health | 38478562 | PLOS Glob Public Health | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38478562 |
Exploring how space, time, and sampling impact our ability to measure genetic structure across Plasmodium falciparum populations. | Arambepola R, Bérubé S, Freedman B, Taylor SM, Prudhomme O'Meara W, Obala AA, Wesolowski A | Frontiers in epidemiology | 38516334 | Front Epidemiol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/38516334 |
Effect of non-pharmaceutical interventions to contain COVID-19 in China. | Lai S, Ruktanonchai NW, Zhou L, Prosper O, Luo W, Floyd JR, Wesolowski A, Santillana M, Zhang C, Du X, Yu H, Tatem AJ | Nature | 32365354 | Nature | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32365354 |
National-scale simulation of human movement in a spatially coupled individual-based model of malaria in Burkina Faso. | Zupko RJ, Nguyen TD, Wesolowski A, Gerardin J, Boni MF | Scientific reports | 36609584 | Sci Rep | 2023 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/36609584 |
Using geospatial models to map zero-dose children: factors associated with zero-dose vaccination status before and after a mass measles and rubella vaccination campaign in Southern province, Zambia. | Arambepola R, Yang Y, Hutchinson K, Mwansa FD, Doherty JA, Bwalya F, Ndubani P, Musukwa G, Moss WJ, Wesolowski A, Mutembo S | BMJ global health | 34969682 | BMJ Glob Health | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34969682 |
Challenges in evaluating risks and policy options around endemic establishment or elimination of novel pathogens. | Metcalf CJE, Andriamandimby SF, Baker RE, Glennon EE, Hampson K, Hollingsworth TD, Klepac P, Wesolowski A | Epidemics | 34823222 | Epidemics | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34823222 |
Prioritizing COVID-19 vaccination efforts and dose allocation within Madagascar. | Rasambainarivo F, Ramiadantsoa T, Raherinandrasana A, Randrianarisoa S, Rice BL, Evans MV, Roche B, Randriatsarafara FM, Wesolowski A, Metcalf JC | BMC public health | 35413894 | BMC Public Health | 2022 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/35413894 |
Rapid real-time tracking of non-pharmaceutical interventions and their association with SARS-CoV-2 positivity: The COVID-19 Pandemic Pulse Study. | Clipman SJ, Wesolowski AP, Gibson DG, Agarwal S, Lambrou AS, Kirk GD, Labrique AB, Mehta SH, Solomon SS | medRxiv : the preprint server for health sciences | 32766598 | medRxiv | 2020 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/32766598 |
Rapid Real-time Tracking of Nonpharmaceutical Interventions and Their Association With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Positivity: The Coronavirus Disease 2019 (COVID-19) Pandemic Pulse Study. | Clipman SJ, Wesolowski AP, Gibson DG, Agarwal S, Lambrou AS, Kirk GD, Labrique AB, Mehta SH, Solomon SS | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 32877921 | Clin Infect Dis | 2021 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/32877921 |
Existing human mobility data sources poorly predicted the spatial spread of SARS-CoV-2 in Madagascar. | Ramiadantsoa T, Metcalf CJE, Raherinandrasana AH, Randrianarisoa S, Rice BL, Wesolowski A, Randriatsarafara FM, Rasambainarivo F | medRxiv : the preprint server for health sciences | 34373863 | medRxiv | 2021 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/34373863 |
Improvements in Severe Acute Respiratory Syndrome Coronavirus 2 Testing Cascade in the United States: Data From Serial Cross-sectional Assessments. | Clipman SJ, Wesolowski A, Mehta SH, Cobey S, Cummings DAT, Solomon SS | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 34374758 | Clin Infect Dis | 2022 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/34374758 |
Characterizing human mobility patterns in rural settings of sub-Saharan Africa. | Meredith HR, Giles JR, Perez-Saez J, Mande T, Rinaldo A, Mutembo S, Kabalo EN, Makungo K, Buckee CO, Tatem AJ, Metcalf CJE, Wesolowski A | eLife | 34533456 | Elife | 2021 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/34533456 |
Towards better targeting: lessons from a posthoneymoon measles outbreak in Madagascar, 2018-2019. | Raherindrasana A, Metcalf CJ, Heraud JM, Cauchemez S, Winter A, Wesolowski A, Razafindratsimandresy R, Randriamampionona L, Rafalimanantsoa SA, Masembe Y, Ndiaye C, Rakotonirina J | BMJ global health | 33082133 | BMJ Glob Health | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33082133 |
Seroprevalence of pertussis in Madagascar and implications for vaccination. | Razafimahatratra SL, Wesolowski A, Rafetrarivony L, Heraud JM, Jones FK, Cauchemez S, Razafindratsimandresy R, Raharinantoanina SJ, Harimanana A, Collard JM, Metcalf CJE | Epidemiology and infection | 33190665 | Epidemiol Infect | 2020 Nov 16 | https://www.ncbi.nlm.nih.gov/pubmed/33190665 |
Changes in mobility patterns during the COVID-19 pandemic in Zambia: Implications for the effectiveness of NPIs in Sub-Saharan Africa. | Loisate S, Mutembo S, Arambepola R, Makungo K, Kabalo EN, Sinyange NB, Kapata N, Liwewe M, Silumezi A, Chongwe G, Kostandova N, Truelove S, Wesolowski A | PLOS global public health | 37906535 | PLOS Glob Public Health | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37906535 |
Impact of disruptions to routine vaccination programs, quantifying burden of measles, and mapping targeted supplementary immunization activities. | Kostandova N, Loisate S, Winter A, Moss WJ, Giles JR, Metcalf CJE, Mutembo S, Wesolowski A | Epidemics | 36343498 | Epidemics | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36343498 |
Fine scale human mobility changes within 26 US cities in 2020 in response to the COVID-19 pandemic were associated with distance and income. | Arambepola R, Schaber KL, Schluth C, Huang AT, Labrique AB, Mehta SH, Solomon SS, Cummings DAT, Wesolowski A | PLOS global public health | 37478056 | PLOS Glob Public Health | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37478056 |
Characterizing mobility patterns and malaria risk factors in semi-nomadic populations of Northern Kenya. | Meredith HR, Wesolowski A, Okoth D, Maraga L, Ambani G, Chepkwony T, Abel L, Kipkoech J, Lokoel G, Esimit D, Lokemer S, Maragia J, O'Meara WP, Obala AA | medRxiv : the preprint server for health sciences | 38106223 | medRxiv | 2023 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/38106223 |
Geography versus sociodemographics as predictors of changes in daily mobility across the USA during the COVID-19 pandemic: a two-stage regression analysis across 26 metropolitan areas. | Schaber K, Arambepola R, Schluth C, Labrique AB, Mehta SH, Solomon SS, Cummings DAT, Wesolowski A | BMJ open | 38986558 | BMJ Open | 2024 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/38986558 |
Clinician Conceptualization of the Benefits of Treatments for Individual Patients. | Morgan DJ, Pineles L, Owczarzak J, Magder L, Scherer L, Brown JP, Pfeiffer C, Terndrup C, Leykum L, Feldstein D, Foy A, Stevens D, Koch C, Masnick M, Weisenberg S, Korenstein D | JAMA network open | 34287630 | JAMA Netw Open | 2021 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/34287630 |
Clinician Attitudes and Beliefs Associated with More Aggressive Diagnostic Testing. | Korenstein D, Scherer LD, Foy A, Pineles L, Lydecker AD, Owczarzak J, Magder L, Brown JP, Pfeiffer CD, Terndrup C, Leykum L, Stevens D, Feldstein DA, Weisenberg SA, Baghdadi JD, Morgan DJ | The American journal of medicine | 35307357 | Am J Med | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35307357 |
Game-based learning to improve diagnostic accuracy: a pilot randomized-controlled trial. | Morgan DJ, Scherer L, Pineles L, Baghdadi J, Magder L, Thom K, Koch C, Wilkins N, LeGrand M, Stevens D, Walker R, Shirrell B, Harris AD, Korenstein D | Diagnosis (Berlin, Germany) | 38284830 | Diagnosis (Berl) | 2024 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/38284830 |
Reply to Fakih and Advani. | Trautner BW, Morgan DJ | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 33821997 | Clin Infect Dis | 2021 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/33821997 |
Exploration of Primary Care Clinician Attitudes and Cognitive Characteristics Associated With Prescribing Antibiotics for Asymptomatic Bacteriuria. | Baghdadi JD, Korenstein D, Pineles L, Scherer LD, Lydecker AD, Magder L, Stevens DN, Morgan DJ | JAMA network open | 35622364 | JAMA Netw Open | 2022 May 2 | https://www.ncbi.nlm.nih.gov/pubmed/35622364 |
Medical overuse of therapies and diagnostics in rheumatology. | Khawaja MN, Alhassan E, Bilal J, Jatwani S, Mehta B, Bhalla V, Morgan DJ, Siaton BC, Hochberg MC | Clinical rheumatology | 33569709 | Clin Rheumatol | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33569709 |
Accuracy of Practitioner Estimates of Probability of Diagnosis Before and After Testing. | Morgan DJ, Pineles L, Owczarzak J, Magder L, Scherer L, Brown JP, Pfeiffer C, Terndrup C, Leykum L, Feldstein D, Foy A, Stevens D, Koch C, Masnick M, Weisenberg S, Korenstein D | JAMA internal medicine | 33818595 | JAMA Intern Med | 2021 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/33818595 |
Clinician Testing and Treatment Thresholds for Management of Urinary Tract Infection. | Harris A, Pineles L, Baghdadiv JD, Magder L, Dhaliwal G, Korenstein D, Harris AD, Morgan DJ | Open forum infectious diseases | 37720701 | Open Forum Infect Dis | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37720701 |
Not Thinking Clearly? Play a Game, Seriously! | Mohan D, Schell J, Angus DC | JAMA | 27825014 | JAMA | 2016 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/27825014 |
Testing a videogame intervention to recalibrate physician heuristics in trauma triage: study protocol for a randomized controlled trial. | Mohan D, Rosengart MR, Fischhoff B, Angus DC, Farris C, Yealy DM, Wallace DJ, Barnato AE | BMC emergency medicine | 27835981 | BMC Emerg Med | 2016 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/27835981 |
Selection bias, interventions and outcomes for survivors of cardiac arrest. | Wallace DJ, Coppler P, Callaway C, Rittenberger JC, Dezfulian C, Mohan D, Toma C, Elmer J | Heart (British Cardiac Society) | 29463613 | Heart | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29463613 |
Using Virtual Reality Simulation Environments to Assess Competence for Emergency Medicine Learners. | McGrath JL, Taekman JM, Dev P, Danforth DR, Mohan D, Kman N, Crichlow A, Bond WF | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | 28888070 | Acad Emerg Med | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/28888070 |
Nudges in the Care of the Critically Ill. | Wallace DJ, Drake C, Mohan D | Critical care medicine | 31305299 | Crit Care Med | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31305299 |
Association of Practitioner Interfacility Triage Performance With Outcomes for Severely Injured Patients With Fee-for-Service Medicare Insurance. | Mohan D, Wallace DJ, Kerti SJ, Angus DC, Rosengart MR, Barnato AE, Yealy DM, Fischhoff B, Chang CC, Kahn JM | JAMA surgery | 31642889 | JAMA Surg | 2019 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/31642889 |
Efficacy of educational video game versus traditional educational apps at improving physician decision making in trauma triage: randomized controlled trial. | Mohan D, Farris C, Fischhoff B, Rosengart MR, Angus DC, Yealy DM, Wallace DJ, Barnato AE | BMJ (Clinical research ed.) | 29233854 | BMJ | 2017 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/29233854 |
Using incentives to recruit physicians into behavioral trials: lessons learned from four studies. | Mohan D, Rosengart MR, Fischhoff B, Angus DC, Wallace DJ, Farris C, Yealy DM, Barnato AE | BMC research notes | 29282154 | BMC Res Notes | 2017 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/29282154 |
Constructing within and between hospital physician social networks for modeling physician research participation. | Bobak CA, Mohan D, Murphy MA, Barnato AE, O'Malley AJ | BMC medical research methodology | 37898745 | BMC Med Res Methodol | 2023 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/37898745 |
Outcomes after a Digital Behavior Change Intervention to Improve Trauma Triage: An Analysis of Medicare Claims. | Mohan D, Chang CC, Fischhoff B, Rosengart MR, Angus DC, Yealy DM, Barnato AE | The Journal of surgical research | 34464890 | J Surg Res | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34464890 |
Serious games may improve physician heuristics in trauma triage. | Mohan D, Fischhoff B, Angus DC, Rosengart MR, Wallace DJ, Yealy DM, Farris C, Chang CH, Kerti S, Barnato AE | Proceedings of the National Academy of Sciences of the United States of America | 30150397 | Proc Natl Acad Sci U S A | 2018 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/30150397 |
Referral Regions for Time-Sensitive Acute Care Conditions in the United States. | Wallace DJ, Mohan D, Angus DC, Driessen JR, Seymour CM, Yealy DM, Roberts MM, Kurland KS, Kahn JM | Annals of emergency medicine | 29606286 | Ann Emerg Med | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29606286 |
Development of a theory-based video-game intervention to increase advance care planning conversations by healthcare providers. | Mohan D, MacMartin MA, Chelen JSC, Maezes CB, Barnato AE | Implementation science communications | 34645515 | Implement Sci Commun | 2021 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/34645515 |
Using a Video Game Intervention to Increase Hospitalists' Advance Care Planning Conversations with Older Adults: a Stepped Wedge Randomized Clinical Trial. | Mohan D, O'Malley AJ, Chelen J, MacMartin M, Murphy M, Rudolph M, Engel JA, Barnato AE | Journal of general internal medicine | 37429972 | J Gen Intern Med | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37429972 |
Using a theory-based, customized video game as an educational tool to improve physicians' trauma triage decisions: study protocol for a randomized cluster trial. | Mohan D, Angus DC, Chang CH, Elmer J, Fischhoff B, Rak KJ, Barnes JL, Peitzman AB, White DB | Trials | 38365758 | Trials | 2024 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/38365758 |
Videogame intervention to increase advance care planning conversations by hospitalists with older adults: study protocol for a stepped-wedge clinical trial. | Mohan D, O'Malley AJ, Chelen J, MacMartin M, Murphy M, Rudolph M, Barnato A | BMJ open | 33753443 | BMJ Open | 2021 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/33753443 |
Does Preexisting Practice Modify How Video Games Recalibrate Physician Heuristics in Trauma Triage? | Kulkarni SS, Barnato AE, Rosengart MR, Fischhoff B, Angus DC, Yealy DM, Wallace DJ, Mohan D | The Journal of surgical research | 31071605 | J Surg Res | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31071605 |
Inner Deliberations of Surgeons Treating Critically-ill Emergency General Surgery Patients: A Qualitative Analysis. | Kulkarni SS, Briggs A, Sacks OA, Rosengart MR, White DB, Barnato AE, Peitzman AB, Mohan D | Annals of surgery | 31714316 | Ann Surg | 2021 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/31714316 |
Defining the representativeness heuristic in trauma triage: A retrospective observational cohort study. | Kulkarni SS, Dewitt B, Fischhoff B, Rosengart MR, Angus DC, Saul M, Yealy DM, Mohan D | PloS one | 30735553 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30735553 |
Testing a Novel Deliberate Practice Intervention to Improve Diagnostic Reasoning in Trauma Triage: A Pilot Randomized Clinical Trial. | Mohan D, Elmer J, Arnold RM, Forsythe RM, Fischhoff B, Rak K, Barnes JL, White DB | JAMA network open | 37195666 | JAMA Netw Open | 2023 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/37195666 |
Testing the feasibility, acceptability, and preliminary effect of a novel deliberate practice intervention to reduce diagnostic error in trauma triage: a study protocol for a randomized pilot trial. | Mohan D, Elmer J, Arnold RM, Forsythe RM, Fischhoff B, Rak K, Barnes JL, White DB | Pilot and feasibility studies | 36510328 | Pilot Feasibility Stud | 2022 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/36510328 |
Localization of EccA(3) at the growing pole in Mycobacterium smegmatis. | Kriel NL, Newton-Foot M, Bennion OT, Aldridge BB, Mehaffy C, Belisle JT, Walzl G, Warren RM, Sampson SL, Gey van Pittius NC | BMC microbiology | 35590245 | BMC Microbiol | 2022 May 19 | https://www.ncbi.nlm.nih.gov/pubmed/35590245 |
Spatially distinct and metabolically active membrane domain in mycobacteria. | Hayashi JM, Luo CY, Mayfield JA, Hsu T, Fukuda T, Walfield AL, Giffen SR, Leszyk JD, Baer CE, Bennion OT, Madduri A, Shaffer SA, Aldridge BB, Sassetti CM, Sandler SJ, Kinoshita T, Moody DB, Morita YS | Proceedings of the National Academy of Sciences of the United States of America | 27114527 | Proc Natl Acad Sci U S A | 2016 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/27114527 |
Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection. | Sukumar N, Tan S, Aldridge BB, Russell DG | PLoS pathogens | 25233380 | PLoS Pathog | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25233380 |
Morphological profiling of tubercle bacilli identifies drug pathways of action. | Smith TC 2nd, Pullen KM, Olson MC, McNellis ME, Richardson I, Hu S, Larkins-Ford J, Wang X, Freundlich JS, Ando DM, Aldridge BB | Proceedings of the National Academy of Sciences of the United States of America | 32680963 | Proc Natl Acad Sci U S A | 2020 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/32680963 |
Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis. | Cokol M, Kuru N, Bicak E, Larkins-Ford J, Aldridge BB | Science advances | 29026882 | Sci Adv | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29026882 |
A Parallel Adder Coordinates Mycobacterial Cell-Cycle Progression and Cell-Size Homeostasis in the Context of Asymmetric Growth and Organization. | Logsdon MM, Ho PY, Papavinasasundaram K, Richardson K, Cokol M, Sassetti CM, Amir A, Aldridge BB | Current biology : CB | 29107550 | Curr Biol | 2017 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/29107550 |
Rv0004 is a new essential member of the mycobacterial DNA replication machinery. | Mann KM, Huang DL, Hooppaw AJ, Logsdon MM, Richardson K, Lee HJ, Kimmey JM, Aldridge BB, Stallings CL | PLoS genetics | 29176877 | PLoS Genet | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/29176877 |
Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling. | Li M, Patel HV, Cognetta AB 3rd, Smith TC 2nd, Mallick I, Cavalier JF, Previti ML, Canaan S, Aldridge BB, Cravatt BF, Seeliger JC | Cell chemical biology | 34599873 | Cell Chem Biol | 2022 May 19 | https://www.ncbi.nlm.nih.gov/pubmed/34599873 |
Stress-Induced Reorganization of the Mycobacterial Membrane Domain. | Hayashi JM, Richardson K, Melzer ES, Sandler SJ, Aldridge BB, Siegrist MS, Morita YS | mBio | 29362232 | mBio | 2018 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/29362232 |
Temporal and intrinsic factors of rifampicin tolerance in mycobacteria. | Richardson K, Bennion OT, Tan S, Hoang AN, Cokol M, Aldridge BB | Proceedings of the National Academy of Sciences of the United States of America | 27357669 | Proc Natl Acad Sci U S A | 2016 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/27357669 |
Prediction of ultra-high-order antibiotic combinations based on pairwise interactions. | Katzir I, Cokol M, Aldridge BB, Alon U | PLoS computational biology | 30699106 | PLoS Comput Biol | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30699106 |
Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis. | Ma S, Jaipalli S, Larkins-Ford J, Lohmiller J, Aldridge BB, Sherman DR, Chandrasekaran S | mBio | 31719182 | mBio | 2019 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/31719182 |
Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action. | Boot M, Commandeur S, Subudhi AK, Bahira M, Smith TC 2nd, Abdallah AM, van Gemert M, Lelièvre J, Ballell L, Aldridge BB, Pain A, Speer A, Bitter W | Antimicrobial agents and chemotherapy | 29661879 | Antimicrob Agents Chemother | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29661879 |
Stable Regulation of Cell Cycle Events in Mycobacteria: Insights From Inherently Heterogeneous Bacterial Populations. | Logsdon MM, Aldridge BB | Frontiers in microbiology | 29619019 | Front Microbiol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29619019 |
Influence of Stress and Antibiotic Resistance on Cell-Length Distribution in Mycobacterium tuberculosis Clinical Isolates. | Vijay S, Vinh DN, Hai HT, Ha VTN, Dung VTM, Dinh TD, Nhung HN, Tram TTB, Aldridge BB, Hanh NT, Thu DDA, Phu NH, Thwaites GE, Thuong NTT | Frontiers in microbiology | 29209302 | Front Microbiol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29209302 |
Foundation models for generalizable electrocardiogram interpretation: comparison of supervised and self-supervised electrocardiogram foundation models. | Nolin-Lapalme A, Sowa A, Delfrate J, Tastet O, Corbin D, Kulbay M, Ozdemir D, Noël MJ, Marois-Blanchet FC, Harvey F, Sharma S, Ansari M, Chiu IM, Dsouza V, Friedman SF, Chassé M, Potter BJ, Afilalo J, Elias PA, Jabbour G, Bahani M, Dubé MP, Boyle PM, Chatterjee NA, Barrios J, Tison GH, Ouyang D, Maddah M, Khurshid S, Cadrin-Tourigny J, Tadros R, Hussin J, Avram R | medRxiv : the preprint server for health sciences | 40093248 | medRxiv | 2025 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/40093248 |
Substrate stiffness modulates cardiac fibroblast activation, senescence, and proinflammatory secretory phenotype. | Felisbino MB, Rubino M, Travers JG, Schuetze KB, Lemieux ME, Anseth KS, Aguado BA, McKinsey TA | American journal of physiology. Heart and circulatory physiology | 37889253 | Am J Physiol Heart Circ Physiol | 2024 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/37889253 |
Secreted Cytokines From Inflammatory Macrophages Modulate Sex Differences in Valvular Interstitial Cells on Hydrogel Biomaterials. | Félix Vélez NE, Tu K, Guo P, Reeves RR, Aguado BA | Journal of biomedical materials research. Part A | 39995146 | J Biomed Mater Res A | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39995146 |
Y chromosome-linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues. | Gorashi RM, Baddour T, Chittle SJ, Félix Vélez NE, Wenning MA, Anseth KS, Mestroni L, Peña B, Guo P, Aguado BA | Science advances | 40073144 | Sci Adv | 2025 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/40073144 |
Y chromosome linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues. | Gorashi RM, Baddour T, Chittle SJ, Vélez NEF, Wenning MA, Anseth KS, Mestroni L, Peña B, Guo P, Aguado BA | bioRxiv : the preprint server for biology | 38798394 | bioRxiv | 2024 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/38798394 |
Reactivation of an Embryonic Cardiac Neural Crest Transcriptional Subcircuit During Zebrafish Heart Regeneration. | Dhillon-Richardson RM, Haugan AK, Lyons LW, McKenna JK, Bronner ME, Martik ML | bioRxiv : the preprint server for biology | 39868190 | bioRxiv | 2025 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/39868190 |
Daily social comparisons among women in midlife with elevated risk for cardiovascular disease: A within-person test of the identification/contrast model. | Baga K, Salvatore GM, Bercovitz I, Mogle JA, Arigo D | Applied psychology. Health and well-being | 38785210 | Appl Psychol Health Well Being | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/38785210 |
A Visual, In-Expensive, and Wireless Capillary Rheometer for Characterizing Wholly-Cellular Bioinks. | Du J, Lee S, Sinha S, Solberg FS, Ho DLL, Sampson JP, Wang Q, Tam T, Skylar-Scott MA | Small (Weinheim an der Bergstrasse, Germany) | 38085139 | Small | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38085139 |
Rapid model-guided design of organ-scale synthetic vasculature for biomanufacturing. | Sexton ZA, Hudson AR, Herrmann JE, Shiwarski DJ, Pham J, Szafron JM, Wu SM, Skylar-Scott M, Feinberg AW, Marsden A | ArXiv | 37645046 | ArXiv | 2023 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/37645046 |
A Low-Cost, Open-Source 3D Printer for Multimaterial and High-Throughput Direct Ink Writing of Soft and Living Materials. | Weiss JD, Mermin-Bunnell A, Solberg FS, Tam T, Rosalia L, Sharir A, Rütsche D, Sinha S, Choi PS, Shibata M, Palagani Y, Nilkant R, Paulvannan K, Ma M, Skylar-Scott MA | Advanced materials (Deerfield Beach, Fla.) | 39748617 | Adv Mater | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39748617 |
Multiscale elasticity mapping of biological samples in 3D at optical resolution. | Regan K, LeBourdais R, Banerji R, Zhang S, Muhvich J, Zheng S, Nia HT | Acta biomaterialia | 38160857 | Acta Biomater | 2024 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/38160857 |
Emergence of nanoscale viscoelasticity from single cancer cells to established tumors. | Hadzipasic M, Zhang S, Huang Z, Passaro R, Sten MS, Shankar GM, Nia HT | Biomaterials | 38169188 | Biomaterials | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38169188 |
The peritumor microenvironment: physics and immunity. | Zhang S, Regan K, Najera J, Grinstaff MW, Datta M, Nia HT | Trends in cancer | 37156677 | Trends Cancer | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37156677 |
Crystal ribcage: a platform for probing real-time lung function at cellular resolution. | Banerji R, Grifno GN, Shi L, Smolen D, LeBourdais R, Muhvich J, Eberman C, Hiller BE, Lee J, Regan K, Zheng S, Zhang S, Jiang J, Raslan AA, Breda JC, Pihl R, Traber K, Mazzilli S, Ligresti G, Mizgerd JP, Suki B, Nia HT | Nature methods | 37710017 | Nat Methods | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37710017 |
B cells in the pneumococcus-infected lung are heterogeneous and require CD4(+) T cell help including CD40L to become resident memory B cells. | Etesami NS, Barker KA, Shenoy AT, De Ana CL, Arafa EI, Grifno GN, Matschulat AM, Vannini ME, Pihl RMF, Breen MP, Soucy AM, Goltry WN, Ha CT, Betsuyaku H, Browning JL, Varelas X, Traber KE, Jones MR, Quinton LJ, Maglione PJ, Nia HT, Belkina AC, Mizgerd JP | Frontiers in immunology | 38715601 | Front Immunol | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38715601 |
Mapping the strain-stiffening behavior of the lung and lung cancer at microscale resolution using the crystal ribcage. | LeBourdais R, Grifno GN, Banerji R, Regan K, Suki B, Nia HT | Frontiers in network physiology | 39050550 | Front Netw Physiol | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/39050550 |
Alteration of mechanical stresses in the murine brain by age and hemorrhagic stroke. | Zheng S, Banerji R, LeBourdais R, Zhang S, DuBois E, O'Shea T, Nia HT | PNAS nexus | 38659974 | PNAS Nexus | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38659974 |
Intravital measurements of solid stresses in tumours reveal length-scale and microenvironmentally dependent force transmission. | Zhang S, Grifno G, Passaro R, Regan K, Zheng S, Hadzipasic M, Banerji R, O'Connor L, Chu V, Kim SY, Yang J, Shi L, Karrobi K, Roblyer D, Grinstaff MW, Nia HT | Nature biomedical engineering | 37640900 | Nat Biomed Eng | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37640900 |
A CAR enhancer increases the activity and persistence of CAR T cells. | Rakhshandehroo T, Mantri SR, Moravej H, Louis BBV, Salehi Farid A, Munaretto L, Regan K, Khan RMM, Wolff A, Farkash Z, Cong M, Kuhnast A, Nili A, Lee UJ, Allen HH, Berland L, Simkova E, Uslu SC, Tavakolpour S, Rowley JE, Codet E, Shahbazian H, Baral J, Pyrdol J, Jacobson CA, Nadeem O, Nia HT, Wucherpfennig KW, Rashidian M | Nature biotechnology | 39079964 | Nat Biotechnol | 2024 Jul 30 | https://www.ncbi.nlm.nih.gov/pubmed/39079964 |
Dreaming of electrical waves: Generative modeling of cardiac excitation waves using diffusion models. | Baranwal T, Lebert J, Christoph J | APL machine learning | 39364376 | APL Mach Learn | 2024 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/39364376 |
Reconstruction of three-dimensional scroll waves in excitable media from two-dimensional observations using deep neural networks. | Lebert J, Mittal M, Christoph J | Physical review. E | 36797900 | Phys Rev E | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36797900 |
Paralysis by analysis: Overcoming cardiac contraction with computer vision. | Christoph J, Ripplinger CM | Proceedings of the National Academy of Sciences of the United States of America | 37792520 | Proc Natl Acad Sci U S A | 2023 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/37792520 |
Author Correction: O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology. | Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR | Nature chemical biology | 38413747 | Nat Chem Biol | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38413747 |
Update on Disease-Specific Biomarkers in Transthyretin Cardiac Amyloidosis. | Hood CJ, Hendren NS, Pedretti R, Roth LR, Saelices L, Grodin JL | Current heart failure reports | 35930129 | Curr Heart Fail Rep | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/35930129 |
Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2. | Tayeb-Fligelman E, Cheng X, Tai C, Bowler JT, Griner S, Sawaya MR, Seidler PM, Jiang YX, Lu J, Rosenberg GM, Salwinski L, Abskharon R, Zee CT, Hou K, Li Y, Boyer DR, Murray KA, Falcon G, Anderson DH, Cascio D, Saelices L, Damoiseaux R, Guo F, Eisenberg DS | bioRxiv : the preprint server for biology | 33688654 | bioRxiv | 2021 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/33688654 |
O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology. | Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR | Nature chemical biology | 38347213 | Nat Chem Biol | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38347213 |
Detection of Circulating Transthyretin Amyloid Aggregates in Plasma: A Novel Biomarker for Transthyretin Amyloidosis. | Pedretti R, Wang L, Hanna M, Benson MD, Grodin JL, Tang WHW, Masri A, Saelices L | Circulation | 38768274 | Circulation | 2024 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/38768274 |
The inhibition of cellular toxicity of amyloid-β by dissociated transthyretin. | Cao Q, Anderson DH, Liang WY, Chou J, Saelices L | The Journal of biological chemistry | 32769117 | J Biol Chem | 2020 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/32769117 |
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. | Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS | Nature communications | 37185252 | Nat Commun | 2023 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/37185252 |
Amyloid fibril polymorphism in the heart of an ATTR amyloidosis patient with polyneuropathy attributed to the V122Δ variant. | Ahmed Y, Nguyen BA, Afrin S, Singh V, Evers B, Singh P, Pedretti R, Wang L, Bassett P, Del Carmen Fernandez-Ramirez M, Pekala M, Kluve-Beckerman B, Saelices L | bioRxiv : the preprint server for biology | 38766262 | bioRxiv | 2024 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/38766262 |
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis. | Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski P, Chhapra F, Saelices L | bioRxiv : the preprint server for biology | 38496656 | bioRxiv | 2024 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/38496656 |
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. | Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pękała M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L | Nature communications | 38233397 | Nat Commun | 2024 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/38233397 |
Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores. | Cao Q, Boyer DR, Sawaya MR, Abskharon R, Saelices L, Nguyen BA, Lu J, Murray KA, Kandeel F, Eisenberg DS | Nature structural & molecular biology | 34518699 | Nat Struct Mol Biol | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34518699 |
Disease-associated patterns of acetylation stabilize tau fibril formation. | Li L, Nguyen B, Mullapudi V, Saelices L, Joachimiak LA | bioRxiv : the preprint server for biology | 36711822 | bioRxiv | 2023 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/36711822 |
O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology. | Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR | bioRxiv : the preprint server for biology | 36945566 | bioRxiv | 2023 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/36945566 |
ATTRv-V30M amyloid fibrils from heart and nerves exhibit structural homogeneity. | Nguyen BA, Afrin S, Yakubovska A, Singh V, Pedretti R, Bassett P, Pekala M, Alicea JV, Kunach P, Wang L, Lemoff A, Kluve-Beckerman B, Saelices L | Structure (London, England : 1993) | 39423808 | Structure | 2024 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/39423808 |
Structure-Based Probe Reveals the Presence of Large Transthyretin Aggregates in Plasma of ATTR Amyloidosis Patients. | Pedretti R, Wang L, Yakubovska A, Zhang QS, Nguyen B, Grodin JL, Masri A, Saelices L | JACC. Basic to translational science | 39444930 | JACC Basic Transl Sci | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39444930 |
Biomarkers in Subclinical Transthyretin Cardiac Amyloidosis. | Gulati JS, Pedretti R, Hendren N, Kozlitina J, Saelices L, Roth LR, Grodin JL | Current heart failure reports | 39945945 | Curr Heart Fail Rep | 2025 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/39945945 |
Conformational inhibitors of protein aggregation. | Fernández Ramírez MDC, Afrin S, Saelices L | Current opinion in structural biology | 37717490 | Curr Opin Struct Biol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37717490 |
Multi-organ structural homogeneity of amyloid fibrils in ATTRv-T60A amyloidosis patients, revealed by Cryo-EM. | Fernandez-Ramirez MDC, Nguyen BA, Singh V, Afrin S, Evers B, Basset P, Wang L, Pękała M, Ahmed Y, Singh P, Canepa J, Wosztyl A, Li Y, Saelices L | bioRxiv : the preprint server for biology | 38798519 | bioRxiv | 2024 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/38798519 |
Disease-associated patterns of acetylation stabilize tau fibril formation. | Li L, Nguyen BA, Mullapudi V, Li Y, Saelices L, Joachimiak LA | Structure (London, England : 1993) | 37348495 | Structure | 2023 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/37348495 |
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis. | Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski PM, Chhapra F, Saelices L | Communications biology | 39068302 | Commun Biol | 2024 Jul 27 | https://www.ncbi.nlm.nih.gov/pubmed/39068302 |
ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity. | Nguyen BA, Afrin S, Yakubovska A, Singh V, Alicea JV, Kunach P, Singh P, Pekala M, Ahmed Y, Fernandez-Ramirez MDC, Hernandez LOC, Pedretti R, Bassett P, Wang L, Lemoff A, Villalon L, Kluve-Beckerman B, Saelices L | bioRxiv : the preprint server for biology | 38798361 | bioRxiv | 2024 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/38798361 |
Detection of ATTR aggregates in the plasma of polyneuropathic patients with ATTR-V30M amyloidosis. | Pedretti R, Wang L, Grodin JL, Masri A, Kelly J, Saelices L | Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis | 39283068 | Amyloid | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39283068 |
Heterogeneity and Functional Analysis of Cardiac Fibroblasts in Heart Development. | Deng Y, He Y, Xu J, He H, Li G | bioRxiv : the preprint server for biology | 37577541 | bioRxiv | 2023 Jul 31 | https://www.ncbi.nlm.nih.gov/pubmed/37577541 |
Cardiac Fibroblasts regulate myocardium and coronary vasculature development via the collagen signaling pathway. | Deng Y, He Y, Xu J, He H, Zhang M, Li G | bioRxiv : the preprint server for biology | 39314489 | bioRxiv | 2025 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/39314489 |
Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency. | Feng W, Schriever H, Jiang S, Bais A, Wu H, Kostka D, Li G | Communications biology | 35488063 | Commun Biol | 2022 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/35488063 |
Modeling Human Heart Development and Congenital Defects Using Organoids: How Close Are We? | Jiang S, Feng W, Chang C, Li G | Journal of cardiovascular development and disease | 35621836 | J Cardiovasc Dev Dis | 2022 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/35621836 |
Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages. | Feng W, Bais A, He H, Rios C, Jiang S, Xu J, Chang C, Kostka D, Li G | Nature communications | 36575170 | Nat Commun | 2022 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/36575170 |
Keratin 19 (Krt19) is a novel marker gene for epicardial cells. | Xu J, Deng Y, Li G | Frontiers in genetics | 38831775 | Front Genet | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38831775 |
Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias. | Haghighi K, Gardner G, Vafiadaki E, Kumar M, Green LC, Ma J, Crocker JS, Koch S, Arvanitis DA, Bidwell P, Rubinstein J, van de Leur R, Doevendans PA, Akar FG, Tranter M, Wang HS, Sadayappan S, DeMazumder D, Sanoudou D, Hajjar RJ, Stillitano F, Kranias EG | Journal of personalized medicine | 34204946 | J Pers Med | 2021 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/34204946 |
Contemporary Applications of Machine Learning for Device Therapy in Heart Failure. | Gautam N, Ghanta SN, Clausen A, Saluja P, Sivakumar K, Dhar G, Chang Q, DeMazumder D, Rabbat MG, Greene SJ, Fudim M, Al'Aref SJ | JACC. Heart failure | 36049812 | JACC Heart Fail | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36049812 |
Artificial Intelligence, Wearables and Remote Monitoring for Heart Failure: Current and Future Applications. | Gautam N, Ghanta SN, Mueller J, Mansour M, Chen Z, Puente C, Ha YM, Tarun T, Dhar G, Sivakumar K, Zhang Y, Halimeh AA, Nakarmi U, Al-Kindi S, DeMazumder D, Al'Aref SJ | Diagnostics (Basel, Switzerland) | 36552971 | Diagnostics (Basel) | 2022 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/36552971 |
Reply: Pathophysiology of Takotsubo Syndrome Explored in the Cardiac Electrophysiology Laboratory. | DeMazumder D, Thirumal R, Wittstein IS, Calkins H | JACC. Clinical electrophysiology | 35589185 | JACC Clin Electrophysiol | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35589185 |
Cardiac sympathetic denervation prevents sudden cardiac arrest and improves cardiac function by enhancing mitochondrial-antioxidant capacity. | Dey S, Joshi P, O'Rourke B, Estes S, DeMazumder D | bioRxiv : the preprint server for biology | 36778270 | bioRxiv | 2023 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/36778270 |
Neurocardiac Changes Preceding and During the Onset of Takotsubo Cardiomyopathy in the Cardiac Electrophysiology Laboratory. | Thirumal R, Wittstein IS, Calkins H, DeMazumder D | JACC. Clinical electrophysiology | 35210091 | JACC Clin Electrophysiol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35210091 |
Ryanodine receptor 2 inhibition reduces dispersion of cardiac repolarization, improves contractile function, and prevents sudden arrhythmic death in failing hearts. | Joshi P, Estes S, DeMazumder D, Knollmann BC, Dey S | eLife | 38078905 | Elife | 2023 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/38078905 |
Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease. | Uddin MDM, Nguyen NQH, Yu B, Brody JA, Pampana A, Nakao T, Fornage M, Bressler J, Sotoodehnia N, Weinstock JS, Honigberg MC, Nachun D, Bhattacharya R, Griffin GK, Chander V, Gibbs RA, Rotter JI, Liu C, Baccarelli AA, Chasman DI, Whitsel EA, Kiel DP, Murabito JM, Boerwinkle E, Ebert BL, Jaiswal S, Floyd JS, Bick AG, Ballantyne CM, Psaty BM, Natarajan P, Conneely KN | Nature communications | 36097025 | Nat Commun | 2022 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/36097025 |
Clonal hematopoiesis associated with epigenetic aging and clinical outcomes. | Nachun D, Lu AT, Bick AG, Natarajan P, Weinstock J, Szeto MD, Kathiresan S, Abecasis G, Taylor KD, Guo X, Tracy R, Durda P, Liu Y, Johnson C, Rich SS, Van Den Berg D, Laurie C, Blackwell T, Papanicolaou GJ, Correa A, Raffield LM, Johnson AD, Murabito J, Manson JE, Desai P, Kooperberg C, Assimes TL, Levy D, Rotter JI, Reiner AP, Whitsel EA, Wilson JG, Horvath S, Jaiswal S, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium | Aging cell | 34050697 | Aging Cell | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34050697 |
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis. | Kim PG, Niroula A, Shkolnik V, McConkey M, Lin AE, Słabicki M, Kemp JP, Bick A, Gibson CJ, Griffin G, Sekar A, Brooks DJ, Wong WJ, Cohen DN, Uddin MM, Shin WJ, Pirruccello J, Tsai JM, Agrawal M, Kiel DP, Bouxsein ML, Richards JB, Evans DM, Wein MN, Charles JF, Jaiswal S, Natarajan P, Ebert BL | The Journal of experimental medicine | 34698806 | J Exp Med | 2021 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/34698806 |
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk. | Yu Z, Fidler TP, Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T, Niroula A, Heimlich JB, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, Levy D, Vasan RS, Aguet F, Ardlie KG, Taylor KD, Rich SS, Rotter JI, Libby P, Jaiswal S, Ebert BL, Bick AG, Tall AR, Natarajan P | The Journal of clinical investigation | 37498674 | J Clin Invest | 2023 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/37498674 |
Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease. | Jaiswal S, Libby P | Nature reviews. Cardiology | 31406340 | Nat Rev Cardiol | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31406340 |
ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. | Beauchamp EM, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Gallì A, Castellano CA, McConkey M, Tarun A, Wong W, Schenone M, Stanclift C, Tanenbaum B, Malolepsza E, Nilsson B, Bick AG, Weinstock JS, Miller M, Niroula A, Dunford A, Taylor-Weiner A, Wood T, Barbera A, Anand S, Psaty BM, Desai P, Cho MH, Johnson AD, Loos R, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, MacArthur DG, Lek M, Exome Aggregation Consortium, Neuberg DS, Lage K, Carr SA, Hellstrom-Lindberg E, Malcovati L, Papaemmanuil E, Stewart C, Getz G, Bradley RK, Jaiswal S, Ebert BL | Blood cancer discovery | 34568833 | Blood Cancer Discov | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34568833 |
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential. | Nakao T, Bick AG, Taub MA, Zekavat SM, Uddin MM, Niroula A, Carty CL, Lane J, Honigberg MC, Weinstock JS, Pampana A, Gibson CJ, Griffin GK, Clarke SL, Bhattacharya R, Assimes TL, Emery LS, Stilp AM, Wong Q, Broome J, Laurie CA, Khan AT, Smith AV, Blackwell TW, Codd V, Nelson CP, Yoneda ZT, Peralta JM, Bowden DW, Irvin MR, Boorgula M, Zhao W, Yanek LR, Wiggins KL, Hixson JE, Gu CC, Peloso GM, Roden DM, Reupena MS, Hwu CM, DeMeo DL, North KE, Kelly S, Musani SK, Bis JC, Lloyd-Jones DM, Johnsen JM, Preuss M, Tracy RP, Peyser PA, Qiao D, Desai P, Curran JE, Freedman BI, Tiwari HK, Chavan S, Smith JA, Smith NL, Kelly TN, Hidalgo B, Cupples LA, Weeks DE, Hawley NL, Minster RL, Samoan Obesity, Lifestyle and Genetic Adaptations Study (OLaGA) Group, Deka R, Naseri TT, de las Fuentes L, Raffield LM, Morrison AC, Vries PS, Ballantyne CM, Kenny EE, Rich SS, Whitsel EA, Cho MH, Shoemaker MB, Pace BS, Blangero J, Palmer ND, Mitchell BD, Shuldiner AR, Barnes KC, Redline S, Kardia SLR, Abecasis GR, Becker LC, Heckbert SR, He J, Post W, Arnett DK, Vasan RS, Darbar D, Weiss ST, McGarvey ST, de Andrade M, Chen YI, Kaplan RC, Meyers DA, Custer BS, Correa A, Psaty BM, Fornage M, Manson JE, Boerwinkle E, Konkle BA, Loos RJF, Rotter JI, Silverman EK, Kooperberg C, Danesh J, Samani NJ, Jaiswal S, Libby P, Ellinor PT, Pankratz N, Ebert BL, Reiner AP, Mathias RA, Do R, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Natarajan P | Science advances | 35385311 | Sci Adv | 2022 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/35385311 |
TET2-mutant clonal hematopoiesis and risk of gout. | Agrawal M, Niroula A, Cunin P, McConkey M, Shkolnik V, Kim PG, Wong WJ, Weeks LD, Lin AE, Miller PG, Gibson CJ, Sekar A, Schaefer IM, Neuberg D, Stone RM, Bick AG, Uddin MM, Griffin GK, Jaiswal S, Natarajan P, Nigrovic PA, Rao DA, Ebert BL | Blood | 35714308 | Blood | 2022 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/35714308 |
Prediction of risk for myeloid malignancy in clonal hematopoiesis. | Weeks LD, Niroula A, Neuberg D, Wong W, Lindsley RC, Luskin M, Berliner N, Stone RM, DeAngelo DJ, Soiffer R, Uddin MM, Griffin G, Vlasschaert C, Gibson CJ, Jaiswal S, Bick AG, Malcovati L, Natarajan P, Ebert BL | NEJM evidence | 37483562 | NEJM Evid | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37483562 |
Clonal haematopoiesis and atherosclerotic cardiovascular disease. | Ahmad H, Jaiswal S | Nature reviews. Cardiology | 37169832 | Nat Rev Cardiol | 2023 Jul | https://www.ncbi.nlm.nih.gov/pubmed/37169832 |
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes. | Weinstock JS, Laurie CA, Broome JG, Taylor KD, Guo X, Shuldiner AR, O'Connell JR, Lewis JP, Boerwinkle E, Barnes KC, Chami N, Kenny EE, Loos RJF, Fornage M, Redline S, Cade BE, Gilliland FD, Chen Z, Gauderman WJ, Kumar R, Grammer L, Schleimer RP, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Qiao D, Weiss ST, Lasky-Su J, DeMeo DL, Palmer ND, Freedman BI, Bowden DW, Cho MH, Vasan RS, Johnson AD, Yanek LR, Becker LC, Kardia S, He J, Kaplan R, Heckbert SR, Smith NL, Wiggins KL, Arnett DK, Irvin MR, Tiwari H, Correa A, Raffield LM, Gao Y, de Andrade M, Rotter JI, Rich SS, Manichaikul AW, Konkle BA, Johnsen JM, Wheeler MM, Custer BS, Duggirala R, Curran JE, Blangero J, Gui H, Xiao S, Williams LK, Meyers DA, Li X, Ortega V, McGarvey S, Gu CC, Chen YI, Lee WJ, Shoemaker MB, Darbar D, Roden D, Albert C, Kooperberg C, Desai P, Blackwell TW, Abecasis GR, Smith AV, Kang HM, Mathias R, Natarajan P, Jaiswal S, Reiner AP, Bick AG, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium | Science advances | 37126548 | Sci Adv | 2023 Apr 28 | https://www.ncbi.nlm.nih.gov/pubmed/37126548 |
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis. | Weinstock JS, Gopakumar J, Burugula BB, Uddin MM, Jahn N, Belk JA, Bouzid H, Daniel B, Miao Z, Ly N, Mack TM, Luna SE, Prothro KP, Mitchell SR, Laurie CA, Broome JG, Taylor KD, Guo X, Sinner MF, von Falkenhausen AS, Kääb S, Shuldiner AR, O'Connell JR, Lewis JP, Boerwinkle E, Barnes KC, Chami N, Kenny EE, Loos RJF, Fornage M, Hou L, Lloyd-Jones DM, Redline S, Cade BE, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Qiao D, Palmer ND, Freedman BI, Bowden DW, Cho MH, DeMeo DL, Vasan RS, Yanek LR, Becker LC, Kardia SLR, Peyser PA, He J, Rienstra M, Van der Harst P, Kaplan R, Heckbert SR, Smith NL, Wiggins KL, Arnett DK, Irvin MR, Tiwari H, Cutler MJ, Knight S, Muhlestein JB, Correa A, Raffield LM, Gao Y, de Andrade M, Rotter JI, Rich SS, Tracy RP, Konkle BA, Johnsen JM, Wheeler MM, Smith JG, Melander O, Nilsson PM, Custer BS, Duggirala R, Curran JE, Blangero J, McGarvey S, Williams LK, Xiao S, Yang M, Gu CC, Chen YI, Lee WJ, Marcus GM, Kane JP, Pullinger CR, Shoemaker MB, Darbar D, Roden DM, Albert C, Kooperberg C, Zhou Y, Manson JE, Desai P, Johnson AD, Mathias RA, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Blackwell TW, Abecasis GR, Smith AV, Kang HM, Satpathy AT, Natarajan P, Kitzman JO, Whitsel EA, Reiner AP, Bick AG, Jaiswal S | Nature | 37046083 | Nature | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37046083 |
Clonal haematopoiesis and risk of chronic liver disease. | Wong WJ, Emdin C, Bick AG, Zekavat SM, Niroula A, Pirruccello JP, Dichtel L, Griffin G, Uddin MM, Gibson CJ, Kovalcik V, Lin AE, McConkey ME, Vromman A, Sellar RS, Kim PG, Agrawal M, Weinstock J, Long MT, Yu B, Banerjee R, Nicholls RC, Dennis A, Kelly M, Loh PR, McCarroll S, Boerwinkle E, Vasan RS, Jaiswal S, Johnson AD, Chung RT, Corey K, Levy D, Ballantyne C, NHLBI TOPMed Hematology Working Group, Ebert BL, Natarajan P | Nature | 37046084 | Nature | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37046084 |
Clonal Hematopoiesis and Its Impact on Human Health. | Ahmad H, Jahn N, Jaiswal S | Annual review of medicine | 36450282 | Annu Rev Med | 2023 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/36450282 |
Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias. | Schuermans A, Vlasschaert C, Nauffal V, Cho SMJ, Uddin MM, Nakao T, Niroula A, Klarqvist MDR, Weeks LD, Lin AE, Saadatagah S, Lannery K, Wong M, Hornsby W, Lubitz SA, Ballantyne C, Jaiswal S, Libby P, Ebert BL, Bick AG, Ellinor PT, Natarajan P, Honigberg MC | European heart journal | 37952204 | Eur Heart J | 2024 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/37952204 |
Human Coronary Plaque T Cells Are Clonal and Cross-React to Virus and Self. | Chowdhury RR, D'Addabbo J, Huang X, Veizades S, Sasagawa K, Louis DM, Cheng P, Sokol J, Jensen A, Tso A, Shankar V, Wendel BS, Bakerman I, Liang G, Koyano T, Fong R, Nau AN, Ahmad H, Gopakumar J, Wirka R, Lee AS, Boyd J, Woo YJ, Quertermous T, Gulati GS, Jaiswal S, Chien YH, Chan CKF, Davis MM, Nguyen PK | Circulation research | 35430876 | Circ Res | 2022 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/35430876 |
Inherited causes of clonal haematopoiesis in 97,691 whole genomes. | Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Sabino EC, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, NHLBI Trans-Omics for Precision Medicine Consortium, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan P | Nature | 33057201 | Nature | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33057201 |
Insights into clonal hematopoiesis and its relation to cancer risk. | Mitchell SR, Gopakumar J, Jaiswal S | Current opinion in genetics & development | 33422951 | Curr Opin Genet Dev | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33422951 |
Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease. | Gumuser ED, Schuermans A, Cho SMJ, Sporn ZA, Uddin MM, Paruchuri K, Nakao T, Yu Z, Haidermota S, Hornsby W, Weeks LD, Niroula A, Jaiswal S, Libby P, Ebert BL, Bick AG, Natarajan P, Honigberg MC | Journal of the American College of Cardiology | 37197843 | J Am Coll Cardiol | 2023 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/37197843 |
Clonal hematopoiesis and nonhematologic disorders. | Jaiswal S | Blood | 32736379 | Blood | 2020 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/32736379 |
Author Correction: Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease. | Jaiswal S, Libby P | Nature reviews. Cardiology | 32616879 | Nat Rev Cardiol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32616879 |
Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood. | Schuermans A, Nakao T, Ruan Y, Koyama S, Yu Z, Uddin MM, Haidermota S, Hornsby W, Lewandowski AJ, Bick AG, Niroula A, Jaiswal S, Ebert BL, Natarajan P, Honigberg MC | Journal of the American Heart Association | 37345823 | J Am Heart Assoc | 2023 Jul 4 | https://www.ncbi.nlm.nih.gov/pubmed/37345823 |
Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics. | Uddin MM, Zhou Y, Bick AG, Burugula BB, Jaiswal S, Desai P, Honigberg MC, Love SA, Barac A, Hayden KM, Manson JE, Whitsel EA, Kooperberg C, Natarajan P, Reiner AP, Kitzman JO | Immunity & ageing : I & A | 35610705 | Immun Ageing | 2022 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/35610705 |
Clonal Hematopoiesis Is Associated With Higher Risk of Stroke. | Bhattacharya R, Zekavat SM, Haessler J, Fornage M, Raffield L, Uddin MM, Bick AG, Niroula A, Yu B, Gibson C, Griffin G, Morrison AC, Psaty BM, Longstreth WT, Bis JC, Rich SS, Rotter JI, Tracy RP, Correa A, Seshadri S, Johnson A, Collins JM, Hayden KM, Madsen TE, Ballantyne CM, Jaiswal S, Ebert BL, Kooperberg C, Manson JE, Whitsel EA, NHLBI Trans-Omics for Precision Medicine Program, Natarajan P, Reiner AP | Stroke | 34743536 | Stroke | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/34743536 |
Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia. | Duncavage EJ, Bagg A, Hasserjian RP, DiNardo CD, Godley LA, Iacobucci I, Jaiswal S, Malcovati L, Vannucchi AM, Patel KP, Arber DA, Arcila ME, Bejar R, Berliner N, Borowitz MJ, Branford S, Brown AL, Cargo CA, Döhner H, Falini B, Garcia-Manero G, Haferlach T, Hellström-Lindberg E, Kim AS, Klco JM, Komrokji R, Lee-Cheun Loh M, Loghavi S, Mullighan CG, Ogawa S, Orazi A, Papaemmanuil E, Reiter A, Ross DM, Savona M, Shimamura A, Skoda RC, Solé F, Stone RM, Tefferi A, Walter MJ, Wu D, Ebert BL, Cazzola M | Blood | 36130297 | Blood | 2022 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/36130297 |
Association of clonal hematopoiesis with chronic obstructive pulmonary disease. | Miller PG, Qiao D, Rojas-Quintero J, Honigberg MC, Sperling AS, Gibson CJ, Bick AG, Niroula A, McConkey ME, Sandoval B, Miller BC, Shi W, Viswanathan K, Leventhal M, Werner L, Moll M, Cade BE, Barr RG, Correa A, Cupples LA, Gharib SA, Jain D, Gogarten SM, Lange LA, London SJ, Manichaikul A, O'Connor GT, Oelsner EC, Redline S, Rich SS, Rotter JI, Ramachandran V, Yu B, Sholl L, Neuberg D, Jaiswal S, Levy BD, Owen CA, Natarajan P, Silverman EK, van Galen P, Tesfaigzi Y, Cho MH, Ebert BL, COPDGene Study Investigators, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium | Blood | 34855941 | Blood | 2022 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/34855941 |
Clonal hematopoiesis is associated with protection from Alzheimer's disease. | Bouzid H, Belk JA, Jan M, Qi Y, Sarnowski C, Wirth S, Ma L, Chrostek MR, Ahmad H, Nachun D, Yao W, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Beiser A, Bick AG, Bis JC, Fornage M, Longstreth WT Jr, Lopez OL, Natarajan P, Psaty BM, Satizabal CL, Weinstock J, Larson EB, Crane PK, Keene CD, Seshadri S, Satpathy AT, Montine TJ, Jaiswal S | Nature medicine | 37322115 | Nat Med | 2023 Jul | https://www.ncbi.nlm.nih.gov/pubmed/37322115 |
Epigenetic and proteomic signatures associate with clonal hematopoiesis expansion rate. | Mack TM, Raddatz MA, Pershad Y, Nachun DC, Taylor KD, Guo X, Shuldiner AR, O'Connell JR, Kenny EE, Loos RJF, Redline S, Cade BE, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Cho MH, DeMeo DL, Levy D, Johnson AD, Mathias RA, Yanek LR, Heckbert SR, Smith NL, Wiggins KL, Raffield LM, Carson AP, Rotter JI, Rich SS, Manichaikul AW, Gu CC, Chen YI, Lee WJ, Shoemaker MB, Roden DM, Kooperberg C, Auer PL, Desai P, Blackwell TW, Smith AV, Reiner AP, Jaiswal S, Weinstock JS, Bick AG | Nature aging | 38834882 | Nat Aging | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38834882 |
Human Plasma Proteomic Profile of Clonal Hematopoiesis. | Yu Z, Vromman A, Nguyen NQH, Schuermans A, Rentz T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir U, Fang S, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Ramachandran VS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg CL, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, NHLBI Trans-Omics for Precision Medicine, Libby P, Gupta RM, Natarajan P | bioRxiv : the preprint server for biology | 39554199 | bioRxiv | 2024 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/39554199 |
InUtero Gene Therapy: Progress and Challenges. | Bose SK, Menon P, Peranteau WH | Trends in molecular medicine | 34176774 | Trends Mol Med | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34176774 |
Foetal genome editing. | Bose SK, Kennedy K, Peranteau WH | Current opinion in obstetrics & gynecology | 36924409 | Curr Opin Obstet Gynecol | 2023 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/36924409 |
In utero pulse injection of isotopic amino acids quantifies protein turnover rates during murine fetal development. | Baeza J, Coons BE, Lin Z, Riley J, Mendoza M, Peranteau WH, Garcia BA | bioRxiv : the preprint server for biology | 37293076 | bioRxiv | 2023 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/37293076 |
Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice. | Riley JS, Luks VL, Berkowitz CL, Dumitru AM, Kus NJ, Dave A, Menon P, De Paepe ME, Jain R, Li L, Dugoff L, Teefey CP, Alameh MG, Zoltick PW, Peranteau WH | The Journal of clinical investigation | 38950310 | J Clin Invest | 2024 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/38950310 |
Molecular and Cellular In Utero Therapy. | Berkowitz CL, Luks VL, Puc M, Peranteau WH | Clinics in perinatology | 36328600 | Clin Perinatol | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36328600 |
Fetal allotransplant recipients are resistant to graft-versus-host disease. | Riley JS, McClain LE, Stratigis JD, Coons BE, Bose SK, Dave A, White BM, Li H, Loukogeorgakis SP, Fachin CG, Dias AIBS, Flake AW, Peranteau WH | Experimental hematology | 36535408 | Exp Hematol | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36535408 |
Improved specificity and efficacy of base-editing therapies with hybrid guide RNAs. | Whittaker MN, Brooks DL, Quigley A, Jindal I, Said H, Qu P, Wang JZ, Ahrens-Nicklas RC, Musunuru K, Alameh MG, Peranteau WH, Wang X | bioRxiv : the preprint server for biology | 38712058 | bioRxiv | 2024 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/38712058 |
Immune modulation permits tolerance and engraftment in a murine model of late-gestation transplantation. | Riley JS, Berkowitz CL, Luks VL, Dave A, Cyril-Olutayo MC, Pogoriler J, Flake AW, Abdulmalik O, Peranteau WH | Blood advances | 38941538 | Blood Adv | 2024 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/38941538 |
In utero hematopoietic cell transplantation leads to sustained engraftment in a mouse model of Fanconi anemia. | Dave A, Liu S, Riley JS, Bose S, Luks V, Berkowitz C, Menon P, Jung S, Li H, Kurre P, Peranteau WH | Blood advances | 37906519 | Blood Adv | 2024 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/37906519 |
Fetal and Maternal Safety Considerations for In Utero Therapy Clinical Trials: iFeTiS Consensus Statement. | Sagar R, Almeida-Porada G, Blakemore K, Chan JKY, Choolani M, Götherström C, Jaulent A, MacKenzie TC, Mattar C, Porada CD, Peranteau WH, Schneider H, Shaw SW, Waddington SN, Westgren M, David AL | Molecular therapy : the journal of the American Society of Gene Therapy | 33069884 | Mol Ther | 2020 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/33069884 |
The Future of In Utero Gene Therapy. | Peranteau WH, Flake AW | Molecular diagnosis & therapy | 32020561 | Mol Diagn Ther | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32020561 |
In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease. | Bose SK, White BM, Kashyap MV, Dave A, De Bie FR, Li H, Singh K, Menon P, Wang T, Teerdhala S, Swaminathan V, Hartman HA, Jayachandran S, Chandrasekaran P, Musunuru K, Jain R, Frank DB, Zoltick P, Peranteau WH | Nature communications | 34257302 | Nat Commun | 2021 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/34257302 |
Prenatal Gene Therapy for Metabolic Disorders. | Coons B, Peranteau WH | Clinical obstetrics and gynecology | 34652302 | Clin Obstet Gynecol | 2021 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/34652302 |
Comment on: Premature delivery in the domestic sow in response to in utero delivery of AAV9 to fetal piglets. | Dave A, Berkowitz CL, Luks VL, White BM, Palanki R, Carpenter MD, Riley JS, Bose SK, Li H, Li L, Menon PV, Teerdhala S, Ebrahimi M, Zoltick PW, Peranteau WH | Gene therapy | 36918654 | Gene Ther | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36918654 |
Fetal gene therapy. | Waddington SN, Peranteau WH, Rahim AA, Boyle AK, Kurian MA, Gissen P, Chan JKY, David AL | Journal of inherited metabolic disease | 37470194 | J Inherit Metab Dis | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/37470194 |
The emerging role of extracellular vesicles in bronchopulmonary dysplasia. | Ransom MA, Blatt AM, Pua HH, Sucre JMS | American journal of physiology. Lung cellular and molecular physiology | 38469633 | Am J Physiol Lung Cell Mol Physiol | 2024 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/38469633 |
Extracellular RNA in oncogenesis, metastasis and drug resistance. | Nelson H, Qu S, Franklin JL, Liu Q, Pua HH, Vickers KC, Weaver AM, Coffey RJ, Patton JG | RNA biology | 39107918 | RNA Biol | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39107918 |
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. | Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ, MISEV Consortium, Théry C, Witwer KW | Journal of extracellular vesicles | 38326288 | J Extracell Vesicles | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38326288 |
Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases. | Song W, Postoak JL, Yang G, Guo X, Pua HH, Bader J, Rathmell JC, Kobayashi H, Haase VH, Leaptrot KL, Schrimpe-Rutledge AC, Sherrod SD, McLean JA, Zhang J, Wu L, Van Kaer L | Proceedings of the National Academy of Sciences of the United States of America | 36574710 | Proc Natl Acad Sci U S A | 2023 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/36574710 |
Extracellular vesicles: mediators of intercellular communication in tissue injury and disease. | Berumen Sánchez G, Bunn KE, Pua HH, Rafat M | Cell communication and signaling : CCS | 34656117 | Cell Commun Signal | 2021 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/34656117 |
Transcriptome Complexity Disentangled: A Regulatory Molecules Approach. | Asiaee A, Abrams ZB, Pua HH, Coombes KR | bioRxiv : the preprint server for biology | 37131792 | bioRxiv | 2025 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/37131792 |
Developmental trajectory of extracellular vesicle characteristics from the lungs of preterm infants. | Ransom MA, Bunn KE, Negretti NM, Jetter CS, Bressman ZJ, Sucre JMS, Pua HH | American journal of physiology. Lung cellular and molecular physiology | 36719083 | Am J Physiol Lung Cell Mol Physiol | 2023 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/36719083 |
MicroRNAs in Macrophages: Regulators of Activation and Function. | Sprenkle NT, Serezani CH, Pua HH | Journal of immunology (Baltimore, Md. : 1950) | 36724439 | J Immunol | 2023 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/36724439 |
RNA regulation in immunity. | Pua H, Ansel KM | Immunological reviews | 34816450 | Immunol Rev | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34816450 |
Multiparametric Single-Vesicle Flow Cytometry Resolves Extracellular Vesicle Heterogeneity and Reveals Selective Regulation of Biogenesis and Cargo Distribution. | von Lersner AK, Fernandes F, Ozawa PMM, Jackson M, Masureel M, Ho H, Lima SM, Vagner T, Sung BH, Wehbe M, Franze K, Pua H, Wilson JT, Irish JM, Weaver AM, Di Vizio D, Zijlstra A | ACS nano | 38578701 | ACS Nano | 2024 Apr 16 | https://www.ncbi.nlm.nih.gov/pubmed/38578701 |
Secret messengers: Extracellular RNA communication in the immune system. | Nation GK, Saffold CE, Pua HH | Immunological reviews | 34542176 | Immunol Rev | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34542176 |
Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors. | Zhu L, Choudhary K, Gonzalez-Teran B, Ang YS, Thomas R, Stone NR, Liu L, Zhou P, Zhu C, Ruan H, Huang Y, Jin S, Pelonero A, Koback F, Padmanabhan A, Sadagopan N, Hsu A, Costa MW, Gifford CA, van Bemmel JG, Hüttenhain R, Vedantham V, Conklin BR, Black BL, Bruneau BG, Steinmetz L, Krogan NJ, Pollard KS, Srivastava D | Circulation | 35938400 | Circulation | 2022 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/35938400 |
Epigenetic Regulation of Cardiomyocyte Maturation by Arginine Methyltransferase CARM1. | Garbutt TA, Wang Z, Wang H, Ma H, Ruan H, Dong Y, Xie Y, Tan L, Phookan R, Stouffer JA, Vedantham V, Yang Y, Qian L, Liu J | Circulation | 38223978 | Circulation | 2024 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/38223978 |
Single Cell Multi-Omics of an iPSC Model of Human Sinoatrial Node Development Reveals Genetic Determinants of Heart Rate and Arrhythmia Susceptibility. | Engel JL, Zhang X, Lu DR, Vila OF, Arias V, Lee J, Hale C, Hsu YH, Li CM, Wu RS, Vedantham V, Ang YS | bioRxiv : the preprint server for biology | 37425707 | bioRxiv | 2023 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/37425707 |
Cholecystokinin-A signaling regulates automaticity of pacemaker cardiomyocytes. | Ruan H, Mandla R, Ravi N, Galang G, Soe AW, Olgin JE, Lang D, Vedantham V | Frontiers in physiology | 38179138 | Front Physiol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/38179138 |
ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function. | Galang G, Mandla R, Ruan H, Jung C, Sinha T, Stone NR, Wu RS, Mannion BJ, Allu PKR, Chang K, Rammohan A, Shi MB, Pennacchio LA, Black BL, Vedantham V | Circulation research | 33044128 | Circ Res | 2020 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/33044128 |
Cholecystokinin-A Signaling Regulates Automaticity of Pacemaker Cardiomyocytes. | Ruan H, Mandla R, Ravi N, Galang G, Soe AW, Olgin JE, Lang D, Vedantham V | bioRxiv : the preprint server for biology | 36747643 | bioRxiv | 2023 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/36747643 |
Transcriptional and Epigenetic Landscape of Cardiac Pacemaker Cells: Insights Into Cellular Specialization in the Sinoatrial Node. | Mandla R, Jung C, Vedantham V | Frontiers in physiology | 34335313 | Front Physiol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34335313 |
Dynamic bioinspired coculture model for probing ER(+) breast cancer dormancy in the bone marrow niche. | Pradhan L, Moore D, Ovadia EM, Swedzinski SL, Cossette T, Sikes RA, van Golen K, Kloxin AM | Science advances | 36888709 | Sci Adv | 2023 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/36888709 |
Tools for probing host-bacteria interactions in the gut microenvironment: From molecular to cellular levels. | Wodzanowski KA, Cassel SE, Grimes CL, Kloxin AM | Bioorganic & medicinal chemistry letters | 32223923 | Bioorg Med Chem Lett | 2020 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/32223923 |
Sequence-defined vinyl sulfonamide click nucleic acids (VS-CNAs) and their assembly into dynamically responsive materials. | Sutherland BP, LeValley PJ, Bischoff DJ, Kloxin AM, Kloxin CJ | Chemical communications (Cambridge, England) | 32820777 | Chem Commun (Camb) | 2020 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/32820777 |
Biomaterials-Based Opportunities to Engineer the Pulmonary Host Immune Response in COVID-19. | Jarai BM, Stillman Z, Bomb K, Kloxin AM, Fromen CA | ACS biomaterials science & engineering | 33356134 | ACS Biomater Sci Eng | 2021 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/33356134 |
Microgels Formed by Spontaneous Click Chemistries Utilizing Microfluidic Flow Focusing for Cargo Release in Response to Endogenous or Exogenous Stimuli. | LeValley PJ, Parsons AL, Sutherland BP, Kiick KL, Oakey JS, Kloxin AM | Pharmaceutics | 35631649 | Pharmaceutics | 2022 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/35631649 |
Systematic d-Amino Acid Substitutions to Control Peptide and Hydrogel Degradation in Cellular Microenvironments. | Bomb K, Zhang Q, Ford EM, Fromen CA, Kloxin AM | ACS macro letters | 37195203 | ACS Macro Lett | 2023 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/37195203 |
Multiscale Invasion Assay for Probing Macrophage Response to Gram-Negative Bacteria. | Wodzanowski KA, Caplan JL, Kloxin AM, Grimes CL | Frontiers in chemistry | 35242744 | Front Chem | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35242744 |
Bridging the gender gap in autoimmunity with T-cell-targeted biomaterials. | López Ruiz A, Slaughter ED, Kloxin AM, Fromen CA | Current opinion in biotechnology | 38377884 | Curr Opin Biotechnol | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38377884 |
Dynamic reporters for probing real-time activation of human fibroblasts from single cells to populations. | Cassel SE, Huntington BM, Chen W, Lei P, Andreadis ST, Kloxin AM | APL bioengineering | 38938687 | APL Bioeng | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38938687 |
Destructive fibrotic teamwork: how both microenvironment stiffness and profibrotic interleukin 13 impair alveolar macrophage phenotype and function. | Bomb K, Pradhan L, Zhang Q, Jarai BM, Bhattacharjee A, Burris DL, Kloxin AM, Fromen CA | Biomaterials science | 36018297 | Biomater Sci | 2022 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/36018297 |
On-demand and tunable dual wavelength release of antibody using light-responsive hydrogels. | LeValley PJ, Sutherland BP, Jaje J, Gibbs S, Jones M, Gala R, Kloxin CJ, Kiick KL, Kloxin AM | ACS applied bio materials | 34327309 | ACS Appl Bio Mater | 2020 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/34327309 |
Rational Design of Hydrogel Networks with Dynamic Mechanical Properties to Mimic Matrix Remodeling. | Wiley KL, Sutherland BP, Ogunnaike BA, Kloxin AM | Advanced healthcare materials | 34936227 | Adv Healthc Mater | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/34936227 |
Combining simulations and experiments for the molecular engineering of multifunctional collagen mimetic peptide-based materials. | Hilderbrand AM, Taylor PA, Stanzione F, LaRue M, Guo C, Jayaraman A, Kloxin AM | Soft matter | 33434255 | Soft Matter | 2021 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/33434255 |
Engineered hydrogels for mechanobiology. | Blache U, Ford EM, Ha B, Rijns L, Chaudhuri O, Dankers PYW, Kloxin AM, Snedeker JG, Gentleman E | Nature reviews. Methods primers | 37461429 | Nat Rev Methods Primers | 2022 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/37461429 |
On the path to predicting immune responses in the lung: Modeling the pulmonary innate immune system at the air-liquid interface (ALI). | Graf J, Trautmann-Rodriguez M, Sabnis S, Kloxin AM, Fromen CA | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences | 37770004 | Eur J Pharm Sci | 2023 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/37770004 |
Harnessing multifunctional collagen mimetic peptides to create bioinspired stimuli responsive hydrogels for controlled cell culture. | Ford EM, Hilderbrand AM, Kloxin AM | Journal of materials chemistry. B | 39211975 | J Mater Chem B | 2024 Oct 2 | https://www.ncbi.nlm.nih.gov/pubmed/39211975 |
Effects of solvent conditions on the self-assembly of heterotrimeric collagen-like peptide (CLP) triple helices: a coarse-grained simulation study. | Taylor PA, Kronenberger S, Kloxin AM, Jayaraman A | Soft matter | 37340986 | Soft Matter | 2023 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/37340986 |
Impact of collagen-like peptide (CLP) heterotrimeric triple helix design on helical thermal stability and hierarchical assembly: a coarse-grained molecular dynamics simulation study. | Taylor PA, Kloxin AM, Jayaraman A | Soft matter | 35380571 | Soft Matter | 2022 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/35380571 |
Rapid Production of Multifunctional Self-Assembling Peptides for Incorporation and Visualization within Hydrogel Biomaterials. | Ford EM, Kloxin AM | ACS biomaterials science & engineering | 34283566 | ACS Biomater Sci Eng | 2021 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/34283566 |
Polygenic prediction of preeclampsia and gestational hypertension. | Honigberg MC, Truong B, Khan RR, Xiao B, Bhatta L, Vy HMT, Guerrero RF, Schuermans A, Selvaraj MS, Patel AP, Koyama S, Cho SMJ, Vellarikkal SK, Trinder M, Urbut SM, Gray KJ, Brumpton BM, Patil S, Zöllner S, Antopia MC, Saxena R, Nadkarni GN, Do R, Yan Q, Pe'er I, Verma SS, Gupta RM, Haas DM, Martin HC, van Heel DA, Laisk T, Natarajan P | Nature medicine | 37248299 | Nat Med | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37248299 |
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases. | Weeks EM, Ulirsch JC, Cheng NY, Trippe BL, Fine RS, Miao J, Patwardhan TA, Kanai M, Nasser J, Fulco CP, Tashman KC, Aguet F, Li T, Ordovas-Montanes J, Smillie CS, Biton M, Shalek AK, Ananthakrishnan AN, Xavier RJ, Regev A, Gupta RM, Lage K, Ardlie KG, Hirschhorn JN, Lander ES, Engreitz JM, Finucane HK | Nature genetics | 37443254 | Nat Genet | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37443254 |
Linking regulation of nitric oxide to endothelin-1: The Yin and Yang of vascular tone in the atherosclerotic plaque. | Gupta RM, Libby P, Barton M | Atherosclerosis | 31810569 | Atherosclerosis | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31810569 |
The March of Monocytes in Atherosclerosis: One Cell at a Time. | Gupta RM, Lee-Kim VS, Libby P | Circulation research | 32379573 | Circ Res | 2020 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/32379573 |
Causal Gene Confusion: The Complicated EDN1/PHACTR1 Locus for Coronary Artery Disease. | Gupta RM | Arteriosclerosis, thrombosis, and vascular biology | 35387481 | Arterioscler Thromb Vasc Biol | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35387481 |
The Role of Endothelial Cells in Atherosclerosis: Insights from Genetic Association Studies. | Pepin ME, Gupta RM | The American journal of pathology | 37827214 | Am J Pathol | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37827214 |
Missing Regulation Between Genetic Association and Transcriptional Abundance for Hypercholesterolemia Genes. | Hakim A, Connally NJ, Schnitzler GR, Cho MH, Jiang ZG, Sunyaev SR, Gupta RM | Genes | 39858631 | Genes (Basel) | 2025 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/39858631 |
The Aging Aorta: Are We Only as Old as Our Endothelium? | Gupta RM, Plutzky J | Arteriosclerosis, thrombosis, and vascular biology | 35080899 | Arterioscler Thromb Vasc Biol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35080899 |
CRISPR-Cas9 Genome Editing of Primary Human Vascular Cells In Vitro. | Atri DS, Lee-Kim VS, Vellarikkal SK, Sias-Garcia O, Yanamandala M, Schniztler GR, Gupta RM | Current protocols | 34748284 | Curr Protoc | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34748284 |
Convergence of coronary artery disease genes onto endothelial cell programs. | Schnitzler GR, Kang H, Fang S, Angom RS, Lee-Kim VS, Ma XR, Zhou R, Zeng T, Guo K, Taylor MS, Vellarikkal SK, Barry AE, Sias-Garcia O, Bloemendal A, Munson G, Guckelberger P, Nguyen TH, Bergman DT, Hinshaw S, Cheng N, Cleary B, Aragam K, Lander ES, Finucane HK, Mukhopadhyay D, Gupta RM, Engreitz JM | Nature | 38326615 | Nature | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38326615 |
Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease. | Zhu QM, Hsu YH, Lassen FH, MacDonald BT, Stead S, Malolepsza E, Kim A, Li T, Mizoguchi T, Schenone M, Guzman G, Tanenbaum B, Fornelos N, Carr SA, Gupta RM, Ellinor PT, Lage K | Communications biology | 38216744 | Commun Biol | 2024 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/38216744 |
Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses. | Wang M, Lee-Kim VS, Atri DS, Elowe NH, Yu J, Garvie CW, Won HH, Hadaya JE, MacDonald BT, Trindade K, Melander O, Rader DJ, Natarajan P, Kathiresan S, Kaushik VK, Khera AV, Gupta RM | Circulation. Genomic and precision medicine | 34592835 | Circ Genom Precis Med | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/34592835 |
Multiomic Analysis and CRISPR Perturbation Screens Identify Endothelial Cell Programs and Novel Therapeutic Targets for Coronary Artery Disease. | Gupta RM, Schnitzler GR, Fang S, Lee-Kim VS, Barry A | Arteriosclerosis, thrombosis, and vascular biology | 36994731 | Arterioscler Thromb Vasc Biol | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/36994731 |
The Coding Logic of Interoception. | Wang RL, Chang RB | Annual review of physiology | 38061018 | Annu Rev Physiol | 2024 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/38061018 |
A multidimensional coding architecture of the vagal interoceptive system. | Zhao Q, Yu CD, Wang R, Xu QJ, Dai Pra R, Zhang L, Chang RB | Nature | 35296859 | Nature | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35296859 |
The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine. | Rajendran PS, Hadaya J, Khalsa SS, Yu C, Chang R, Shivkumar K | Seminars in cell & developmental biology | 36641366 | Semin Cell Dev Biol | 2024 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/36641366 |
Differential developmental blueprints of organ-intrinsic nervous systems. | Hsu IU, Lin Y, Guo Y, Xu QJ, Shao Y, Wang RL, Yin D, Zhao J, Young LH, Zhao H, Zhang L, Chang RB | bioRxiv : the preprint server for biology | 38168446 | bioRxiv | 2023 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/38168446 |
Vagal sensory neurons and gut-brain signaling. | Yu CD, Xu QJ, Chang RB | Current opinion in neurobiology | 32380360 | Curr Opin Neurobiol | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32380360 |
Cardiovascular Brain Circuits. | Mohanta SK, Yin C, Weber C, Godinho-Silva C, Veiga-Fernandes H, Xu QJ, Chang RB, Habenicht AJR | Circulation research | 37228235 | Circ Res | 2023 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/37228235 |
Regulation of Cardiac Function by the Autonomic Nervous System. | Hafez OA, Chang RB | Physiology (Bethesda, Md.) | 39585760 | Physiology (Bethesda) | 2025 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/39585760 |
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues. | Zhao T, Chiang ZD, Morriss JW, LaFave LM, Murray EM, Del Priore I, Meli K, Lareau CA, Nadaf NM, Li J, Earl AS, Macosko EZ, Jacks T, Buenrostro JD, Chen F | Nature | 34912115 | Nature | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34912115 |
Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma. | LaFave LM, Kartha VK, Ma S, Meli K, Del Priore I, Lareau C, Naranjo S, Westcott PMK, Duarte FM, Sankar V, Chiang Z, Brack A, Law T, Hauck H, Okimoto A, Regev A, Buenrostro JD, Jacks T | Cancer cell | 32707078 | Cancer Cell | 2020 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/32707078 |
Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements. | Hu Y, Ma S, Kartha VK, Duarte FM, Horlbeck M, Zhang R, Shrestha R, Labade A, Kletzien H, Meliki A, Castillo A, Durand N, Mattei E, Anderson LJ, Tay T, Earl AS, Shoresh N, Epstein CB, Wagers A, Buenrostro JD | bioRxiv : the preprint server for biology | 37034577 | bioRxiv | 2023 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/37034577 |
A transcription factor atlas of directed differentiation. | Joung J, Ma S, Tay T, Geiger-Schuller KR, Kirchgatterer PC, Verdine VK, Guo B, Arias-Garcia MA, Allen WE, Singh A, Kuksenko O, Abudayyeh OO, Gootenberg JS, Fu Z, Macrae RK, Buenrostro JD, Regev A, Zhang F | Cell | 36608654 | Cell | 2023 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/36608654 |
A microRNA expression and regulatory element activity atlas of the mouse immune system. | Rose SA, Wroblewska A, Dhainaut M, Yoshida H, Shaffer JM, Bektesevic A, Ben-Zvi B, Rhoads A, Kim EY, Yu B, Lavin Y, Merad M, Buenrostro JD, Brown BD, Immunological Genome Consortium | Nature immunology | 34099919 | Nat Immunol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34099919 |
Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin. | Ma S, Zhang B, LaFave LM, Earl AS, Chiang Z, Hu Y, Ding J, Brack A, Kartha VK, Tay T, Law T, Lareau C, Hsu YC, Regev A, Buenrostro JD | Cell | 33098772 | Cell | 2020 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/33098772 |
Functional inference of gene regulation using single-cell multi-omics. | Kartha VK, Duarte FM, Hu Y, Ma S, Chew JG, Lareau CA, Earl A, Burkett ZD, Kohlway AS, Lebofsky R, Buenrostro JD | Cell genomics | 36204155 | Cell Genom | 2022 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/36204155 |
Multiscale footprints reveal the organization of cis-regulatory elements. | Hu Y, Horlbeck MA, Zhang R, Ma S, Shrestha R, Kartha VK, Duarte FM, Hock C, Savage RE, Labade A, Kletzien H, Meliki A, Castillo A, Durand NC, Mattei E, Anderson LJ, Tay T, Earl AS, Shoresh N, Epstein CB, Wagers AJ, Buenrostro JD | Nature | 39843737 | Nature | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39843737 |
Reprogramming identifies functionally distinct stages of clonal evolution in myelodysplastic syndromes. | Hsu J, Reilly A, Hayes BJ, Clough CA, Konnick EQ, Torok-Storb B, Gulsuner S, Wu D, Becker PS, Keel SB, Abkowitz JL, Doulatov S | Blood | 31010849 | Blood | 2019 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/31010849 |
R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts. | Liu ZS, Sinha S, Bannister M, Song A, Arriaga-Gomez E, McKeeken AJ, Bonner EA, Hanson BK, Sarchi M, Takashima K, Zong D, Corral VM, Nguyen E, Yoo J, Chiraphapphaiboon W, Leibson C, McMahon MC, Rai S, Swisher EM, Sachs Z, Chatla S, Stirewalt DL, Deeg HJ, Skorski T, Papapetrou EP, Walter MJ, Graubert TA, Doulatov S, Lee SC, Nguyen HD | Cancer research | 37967363 | Cancer Res | 2024 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/37967363 |
ATG4A regulates human erythroid maturation and mitochondrial clearance. | Stolla MC, Reilly A, Bergantinos R, Stewart S, Thom N, Clough CA, Wellington RC, Stolitenko R, Abkowitz JL, Doulatov S | Blood advances | 35443024 | Blood Adv | 2022 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/35443024 |
Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function. | Reilly A, Philip Creamer J, Stewart S, Stolla MC, Wang Y, Du J, Wellington R, Busch S, Estey EH, Becker PS, Fang M, Keel SB, Abkowitz JL, Soma LA, Ma J, Duan Z, Doulatov S | Cell stem cell | 35278369 | Cell Stem Cell | 2022 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/35278369 |
Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells. | Wellington R, Cheng X, Campbell CA, Trapnell C, Espin-Palazon R, Hadland B, Doulatov S | bioRxiv : the preprint server for biology | 39386462 | bioRxiv | 2024 Nov 22 | https://www.ncbi.nlm.nih.gov/pubmed/39386462 |
Induced pluripotent stem cell line (SDQLCHi041-A) from a male patient with mucopolysaccharidosis type IIIB. | Guan J, Tian G, Dong R, Zhang H, Yang X, Li Y, Gai Z, Liu Y | Stem cell research | 33550137 | Stem Cell Res | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33550137 |
Induced pluripotent stem cell models of myeloid malignancies and clonal evolution. | Reilly A, Doulatov S | Stem cell research | 33592565 | Stem Cell Res | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33592565 |
Studying clonal evolution of myeloid malignancies using induced pluripotent stem cells. | Doulatov S, Papapetrou EP | Current opinion in hematology | 33264225 | Curr Opin Hematol | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33264225 |
Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome. | Clough CA, Pangallo J, Sarchi M, Ilagan JO, North K, Bergantinos R, Stolla MC, Naru J, Nugent P, Kim E, Stirewalt DL, Subramaniam AR, Abdel-Wahab O, Abkowitz JL, Bradley RK, Doulatov S | Blood | 34861039 | Blood | 2022 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/34861039 |
Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition. | Sarchi M, Clough CA, Crosse EI, Kim J, Baquero Galvis LD, Aydinyan N, Wellington R, Yang F, Gallì A, Creamer JP, Stewart S, Bradley RK, Malcovati L, Doulatov S | Blood cancer discovery | 38856693 | Blood Cancer Discov | 2024 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/38856693 |
Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate. | Shiraishi K, Shah PP, Morley MP, Loebel C, Santini GT, Katzen J, Basil MC, Lin SM, Planer JD, Cantu E, Jones DL, Nottingham AN, Li S, Cardenas-Diaz FL, Zhou S, Burdick JA, Jain R, Morrisey EE | Cell | 36870331 | Cell | 2023 Mar 30 | https://www.ncbi.nlm.nih.gov/pubmed/36870331 |
Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors. | Smith CL, Lan Y, Jain R, Epstein JA, Poleshko A | Science advances | 34559565 | Sci Adv | 2021 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/34559565 |
Picking Winners and Losers: Cell Competition in Tissue Development and Homeostasis. | Kim W, Jain R | Trends in genetics : TIG | 32418713 | Trends Genet | 2020 Jul | https://www.ncbi.nlm.nih.gov/pubmed/32418713 |
Early lineage specification defines alveolar epithelial ontogeny in the murine lung. | Frank DB, Penkala IJ, Zepp JA, Sivakumar A, Linares-Saldana R, Zacharias WJ, Stolz KG, Pankin J, Lu M, Wang Q, Babu A, Li L, Zhou S, Morley MP, Jain R, Morrisey EE | Proceedings of the National Academy of Sciences of the United States of America | 30782824 | Proc Natl Acad Sci U S A | 2019 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/30782824 |
H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis. | Poleshko A, Smith CL, Nguyen SC, Sivaramakrishnan P, Wong KG, Murray JI, Lakadamyali M, Joyce EF, Jain R, Epstein JA | eLife | 31573510 | Elife | 2019 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/31573510 |
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. | Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, Owens AT, Margulies KB, Frank DB, Wu JC, Rader DJ, Yang W, Prosser BL, Musunuru K, Jain R | Cell stem cell | 33529599 | Cell Stem Cell | 2021 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/33529599 |
PRR14 organizes H3K9me3-modified heterochromatin at the nuclear lamina. | Kiseleva AA, Cheng YC, Smith CL, Katz RA, Poleshko A | Nucleus (Austin, Tex.) | 36633363 | Nucleus | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36633363 |
A Balance Between Intermediate Filaments and Microtubules Maintains Nuclear Architecture in the Cardiomyocyte. | Heffler J, Shah PP, Robison P, Phyo S, Veliz K, Uchida K, Bogush A, Rhoades J, Jain R, Prosser BL | Circulation research | 31822208 | Circ Res | 2020 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/31822208 |
A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis. | Berg DA, Su Y, Jimenez-Cyrus D, Patel A, Huang N, Morizet D, Lee S, Shah R, Ringeling FR, Jain R, Epstein JA, Wu QF, Canzar S, Ming GL, Song H, Bond AM | Cell | 30929900 | Cell | 2019 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/30929900 |
Aberrant chromatin organization at the nexus of laminopathy disease pathways. | Santini GT, Shah PP, Karnay A, Jain R | Nucleus (Austin, Tex.) | 36503349 | Nucleus | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36503349 |
An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype. | Shah PP, Keough KC, Gjoni K, Santini GT, Abdill RJ, Wickramasinghe NM, Dundes CE, Karnay A, Chen A, Salomon REA, Walsh PJ, Nguyen SC, Whalen S, Joyce EF, Loh KM, Dubois N, Pollard KS, Jain R | Genome biology | 36691074 | Genome Biol | 2023 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/36691074 |
Lineage-specific reorganization of nuclear peripheral heterochromatin and H3K9me2 domains. | See K, Lan Y, Rhoades J, Jain R, Smith CL, Epstein JA | Development (Cambridge, England) | 30723106 | Development | 2019 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/30723106 |
Core Components of the Nuclear Pore Bind Distinct States of Chromatin and Contribute to Polycomb Repression. | Gozalo A, Duke A, Lan Y, Pascual-Garcia P, Talamas JA, Nguyen SC, Shah PP, Jain R, Joyce EF, Capelson M | Molecular cell | 31784359 | Mol Cell | 2020 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/31784359 |
A LAMP sequencing approach for high-throughput co-detection of SARS-CoV-2 and influenza virus in human saliva. | Warneford-Thomson R, Shah PP, Lundgren P, Lerner J, Morgan J, Davila A, Abella BS, Zaret K, Schug J, Jain R, Thaiss CA, Bonasio R | eLife | 35532013 | Elife | 2022 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/35532013 |
Cell type determination for cardiac differentiation occurs soon after seeding of human-induced pluripotent stem cells. | Jiang CL, Goyal Y, Jain N, Wang Q, Truitt RE, Coté AJ, Emert B, Mellis IA, Kiani K, Yang W, Jain R, Raj A | Genome biology | 35382863 | Genome Biol | 2022 Apr 5 | https://www.ncbi.nlm.nih.gov/pubmed/35382863 |
InterLINCing Chromatin Organization and Mechanobiology in Laminopathies. | Shah PP, Santini GT, Shen KM, Jain R | Current cardiology reports | 37052760 | Curr Cardiol Rep | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37052760 |
Nanotherapeutics Engineered to Cross the Blood-Brain Barrier for Advanced Drug Delivery to the Central Nervous System. | Kim J, Ahn SI, Kim Y | Journal of industrial and engineering chemistry (Seoul, Korea) | 31588177 | J Ind Eng Chem | 2019 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/31588177 |
Advanced Human BBB-on-a-Chip: A New Platform for Alzheimer's Disease Studies. | Yoon JK, Kim J, Shah Z, Awasthi A, Mahajan A, Kim Y | Advanced healthcare materials | 34075728 | Adv Healthc Mater | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34075728 |
Engineered biomimetic nanoparticle for dual targeting of the cancer stem-like cell population in sonic hedgehog medulloblastoma. | Kim J, Dey A, Malhotra A, Liu J, Ahn SI, Sei YJ, Kenney AM, MacDonald TJ, Kim Y | Proceedings of the National Academy of Sciences of the United States of America | 32934143 | Proc Natl Acad Sci U S A | 2020 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/32934143 |
Engineered Heterochronic Parabiosis in 3D Microphysiological System for Identification of Muscle Rejuvenating Factors. | Lee Y, Choi JJ, Ahn SI, Lee NH, Han WM, Mohiuddin M, Shin EJ, Wood L, Park KD, Kim Y, Jang YC | Advanced functional materials | 38053980 | Adv Funct Mater | 2020 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/38053980 |
Detecting the functional complexities between high-density lipoprotein mimetics. | Sei YJ, Ahn J, Kim T, Shin E, Santiago-Lopez AJ, Jang SS, Jeon NL, Jang YC, Kim Y | Biomaterials | 29653287 | Biomaterials | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29653287 |
Microvascularized tumor organoids-on-chips: advancing preclinical drug screening with pathophysiological relevance. | Lim J, Ching H, Yoon JK, Jeon NL, Kim Y | Nano convergence | 33846849 | Nano Converg | 2021 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/33846849 |
Polymeric Nanoparticles Controlled by On-Chip Self-Assembly Enhance Cancer Treatment Effectiveness. | Jung S, Lee J, Lim J, Suh J, Kim T, Ahn J, Kim WJ, Kim Y | Advanced healthcare materials | 33073526 | Adv Healthc Mater | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33073526 |
Estimating Cardiac Sympathetic Activity From Subcutaneous Nerve Recordings: More Than Skin Deep? | Dusi V, Ajijola OA | JACC. Clinical electrophysiology | 29798800 | JACC Clin Electrophysiol | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29798800 |
Neuromodulation Approaches for Cardiac Arrhythmias: Recent Advances. | Dusi V, Zhu C, Ajijola OA | Current cardiology reports | 30887264 | Curr Cardiol Rep | 2019 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/30887264 |
Aorticorenal ganglion as a novel target for renal neuromodulation. | Hori Y, Temma T, Wooten C, Sobowale C, Tahmasian S, Chan C, Swid MA, Zuckerman JE, Peacock W, Ajijola OA | Heart rhythm | 34182169 | Heart Rhythm | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/34182169 |
Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity. | Liu K, Li D, Hao G, McCaffary D, Neely O, Woodward L, Ioannides D, Lu CJ, Brescia M, Zaccolo M, Tandri H, Ajijola OA, Ardell JL, Shivkumar K, Paterson DJ | JCI insight | 29720569 | JCI Insight | 2018 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/29720569 |
Cardiac vanilloid receptor-1 afferent depletion enhances stellate ganglion neuronal activity and efferent sympathetic response to cardiac stress. | Yoshie K, Rajendran PS, Massoud L, Kwon O, Tadimeti V, Salavatian S, Ardell JL, Shivkumar K, Ajijola OA | American journal of physiology. Heart and circulatory physiology | 29351450 | Am J Physiol Heart Circ Physiol | 2018 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/29351450 |
Transcriptional profiling of stellate ganglia from normotensive and spontaneously hypertensive rat strains. | Davis H, Bardsley EN, Paterson DJ | Scientific data | 29944142 | Sci Data | 2018 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/29944142 |
Managing ventricular arrhythmias after failed catheter ablation: Interrupting the reentrant loop of repeat ablation. | Yoshie K, Ajijola OA | Heart rhythm | 28958931 | Heart Rhythm | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28958931 |
Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review. | Meng L, Tseng CH, Shivkumar K, Ajijola O | JACC. Clinical electrophysiology | 29270467 | JACC Clin Electrophysiol | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/29270467 |
RNA Sequencing Reveals Novel Transcripts from Sympathetic Stellate Ganglia During Cardiac Sympathetic Hyperactivity. | Bardsley EN, Davis H, Ajijola OA, Buckler KJ, Ardell JL, Shivkumar K, Paterson DJ | Scientific reports | 29872217 | Sci Rep | 2018 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/29872217 |
Prognostic impact of atrial rhythm and dimension in patients with structural heart disease undergoing cardiac sympathetic denervation for ventricular arrhythmias. | Dusi V, Sorg JM, Gornbein J, Gima J, Yanagawa J, Lee JM, Vecerek N, Vaseghi M, Bradfield JS, De Ferrari GM, Shivkumar K, Ajijola OA | Heart rhythm | 31837474 | Heart Rhythm | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/31837474 |
Cardiac TRPV1 afferent signaling promotes arrhythmogenic ventricular remodeling after myocardial infarction. | Yoshie K, Rajendran PS, Massoud L, Mistry J, Swid MA, Wu X, Sallam T, Zhang R, Goldhaber JI, Salavatian S, Ajijola OA | JCI insight | 31846438 | JCI Insight | 2020 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/31846438 |
Chronic Kidney Disease: A Nerve-Racking Situation for the Heart. | Ajijola OA | Circulation research | 35209720 | Circ Res | 2022 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/35209720 |
The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade. | Kalla M, Hao G, Tapoulal N, Tomek J, Liu K, Woodward L, ‘Oxford Acute Myocardial Infarction (OxAMI) Study’, Dall'Armellina E, Banning AP, Choudhury RP, Neubauer S, Kharbanda RK, Channon KM, Ajijola OA, Shivkumar K, Paterson DJ, Herring N | European heart journal | 31834357 | Eur Heart J | 2020 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/31834357 |
3D-Printed Coronary Implants Are Effective for Percutaneous Creation of Swine Models with Focal Coronary Stenosis. | Colbert CM, Shao J, Hollowed JJ, Currier JW, Ajijola OA, Fishbein GA, Duarte-Vogel SM, Dharmakumar R, Hu P, Nguyen KL | Journal of cardiovascular translational research | 32394352 | J Cardiovasc Transl Res | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32394352 |
Inflammation, oxidative stress, and glial cell activation characterize stellate ganglia from humans with electrical storm. | Ajijola OA, Hoover DB, Simerly TM, Brown TC, Yanagawa J, Biniwale RM, Lee JM, Sadeghi A, Khanlou N, Ardell JL, Shivkumar K | JCI insight | 28931760 | JCI Insight | 2017 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/28931760 |
Cardiac afferent signaling partially underlies premature ventricular contraction-induced cardiomyopathy. | Hori Y, Temma T, Wooten C, Sobowale C, Chan C, Swid M, Ajijola OA | Heart rhythm | 33845214 | Heart Rhythm | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/33845214 |
Tiered sympathetic control of cardiac function revealed by viral tracing and single cell transcriptome profiling. | Sharma S, Littman R, Tompkins JD, Arneson D, Contreras J, Dajani AH, Ang K, Tsanhani A, Sun X, Jay PY, Herzog H, Yang X, Ajijola OA | eLife | 37162194 | Elife | 2023 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/37162194 |
Cardiac sympathetic denervation and mental health. | Khalsa SS, Clausen AN, Shahabi L, Sorg J, Gonzalez SE, Naliboff B, Shivkumar K, Ajijola OA | Autonomic neuroscience : basic & clinical | 33631539 | Auton Neurosci | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33631539 |
Single-cell transcriptomic profiling of satellite glial cells in stellate ganglia reveals developmental and functional axial dynamics. | van Weperen VYH, Littman RJ, Arneson DV, Contreras J, Yang X, Ajijola OA | Glia | 33432730 | Glia | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33432730 |
Cardiovascular autonomic reflex function after bilateral cardiac sympathetic denervation for ventricular arrhythmias. | Dusi V, Shahabi L, Lapidus RC, Sorg JM, Naliboff BD, Shivkumar K, Khalsa SS, Ajijola OA | Heart rhythm | 32325196 | Heart Rhythm | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32325196 |
Circulating Neuropeptide Y as a Biomarker for Neuromodulation in Atrial Fibrillation. | Stavrakis S, Morris L, Takashima AD, Elkholey K, Van Wagoner DR, Ajijola OA | JACC. Clinical electrophysiology | 33213819 | JACC Clin Electrophysiol | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33213819 |
Coronary Sinus Neuropeptide Y Levels and Adverse Outcomes in Patients With Stable Chronic Heart Failure. | Ajijola OA, Chatterjee NA, Gonzales MJ, Gornbein J, Liu K, Li D, Paterson DJ, Shivkumar K, Singh JP, Herring N | JAMA cardiology | 31876927 | JAMA Cardiol | 2020 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/31876927 |
A novel metric linking stellate ganglion neuronal population dynamics to cardiopulmonary physiology. | Sudarshan KB, Hori Y, Swid MA, Karavos AC, Wooten C, Armour JA, Kember G, Ajijola OA | American journal of physiology. Heart and circulatory physiology | 34213390 | Am J Physiol Heart Circ Physiol | 2021 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/34213390 |
The derivative of tissue activation as a marker of arrhythmogenic myocardium. | Temma T, Lux RL, Yoshie K, Hayase J, Bradfield JS, Shivkumar K, Ajijola OA | Heart rhythm | 36270579 | Heart Rhythm | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36270579 |
Dissecting Cell-Type Composition and Activity-Dependent Transcriptional State in Mammalian Brains by Massively Parallel Single-Nucleus RNA-Seq. | Hu P, Fabyanic E, Kwon DY, Tang S, Zhou Z, Wu H | Molecular cell | 29220646 | Mol Cell | 2017 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/29220646 |
Massively parallel and time-resolved RNA sequencing in single cells with scNT-seq. | Qiu Q, Hu P, Qiu X, Govek KW, Cámara PG, Wu H | Nature methods | 32868927 | Nat Methods | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32868927 |
Tet2-mediated epigenetic drive for astrocyte differentiation from embryonic neural stem cells. | He F, Wu H, Zhou L, Lin Q, Cheng Y, Sun YE | Cell death discovery | 32377393 | Cell Death Discov | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32377393 |
Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects. | Fabyanic EB, Hu P, Qiu Q, Berríos KN, Connolly DR, Wang T, Flournoy J, Zhou Z, Kohli RM, Wu H | Nature biotechnology | 37640946 | Nat Biotechnol | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37640946 |
Single-cell transcriptomic analysis of adult mouse pituitary reveals sexual dimorphism and physiologic demand-induced cellular plasticity. | Ho Y, Hu P, Peel MT, Chen S, Camara PG, Epstein DJ, Wu H, Liebhaber SA | Protein & cell | 32193873 | Protein Cell | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32193873 |
Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts. | Hu P, Liu J, Zhao J, Wilkins BJ, Lupino K, Wu H, Pei L | Genes & development | 30254108 | Genes Dev | 2018 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/30254108 |
Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase. | Schutsky EK, DeNizio JE, Hu P, Liu MY, Nabel CS, Fabyanic EB, Hwang Y, Bushman FD, Wu H, Kohli RM | Nature biotechnology | 30295673 | Nat Biotechnol | 2018 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/30295673 |
Mammalian DNA methylome dynamics: mechanisms, functions and new frontiers. | Wei A, Wu H | Development (Cambridge, England) | 36519514 | Development | 2022 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/36519514 |
Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia. | Chen C, Yu W, Alikarami F, Qiu Q, Chen CH, Flournoy J, Gao P, Uzun Y, Fang L, Davenport JW, Hu Y, Zhu Q, Wang K, Libbrecht C, Felmeister A, Rozich I, Ding YY, Hunger SP, Felix CA, Wu H, Brown PA, Guest EM, Barrett DM, Bernt KM, Tan K | Blood | 34864916 | Blood | 2022 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/34864916 |
Inflammatory Bowel Disease-Associated Gut Commensals Degrade Components of the Extracellular Matrix. | Porras AM, Zhou H, Shi Q, Xiao X, JRI Live Cell Bank, Longman R, Brito IL | mBio | 36445085 | mBio | 2022 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/36445085 |
Host-microbiome protein-protein interactions capture disease-relevant pathways. | Zhou H, Beltrán JF, Brito IL | Genome biology | 35246229 | Genome Biol | 2022 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/35246229 |
Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C. | Kent AG, Vill AC, Shi Q, Satlin MJ, Brito IL | Nature communications | 32873785 | Nat Commun | 2020 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/32873785 |
Structural insight into protein-protein interactions between intestinal microbiome and host. | Post SE, Brito IL | Current opinion in structural biology | 35390637 | Curr Opin Struct Biol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35390637 |
Clinically relevant antibiotic resistance genes are linked to a limited set of taxa within gut microbiome worldwide. | Diebold PJ, Rhee MW, Shi Q, Trung NV, Umrani F, Ahmed S, Kulkarni V, Deshpande P, Alexander M, Thi Hoa N, Christakis NA, Iqbal NT, Ali SA, Mathad JS, Brito IL | Nature communications | 37963868 | Nat Commun | 2023 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/37963868 |
Structural host immune-microbiota interactions. | Brito IL, Kriegel MA | Current opinion in structural biology | 36063760 | Curr Opin Struct Biol | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36063760 |
Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming. | Jones J, Shi Q, Nath RR, Brito IL | PloS one | 38363784 | PLoS One | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38363784 |
Lupus and inflammatory bowel disease share a common set of microbiome features distinct from other autoimmune disorders. | Zhou H, Balint D, Shi Q, Vartanian T, Kriegel MA, Brito I | Annals of the rheumatic diseases | 39874239 | Ann Rheum Dis | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39874239 |
Examining horizontal gene transfer in microbial communities. | Brito IL | Nature reviews. Microbiology | 33846600 | Nat Rev Microbiol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33846600 |
Highly multiplexed spatial mapping of microbial communities. | Shi H, Shi Q, Grodner B, Lenz JS, Zipfel WR, Brito IL, De Vlaminck I | Nature | 33268897 | Nature | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33268897 |
Prevotella copri variants among a single host diverge in sphingolipid production. | Xiao X, Le HH, Lee M-T, Lamm D, Johnson EL, Brito IL | mBio | 38236049 | mBio | 2024 Feb 14 | https://www.ncbi.nlm.nih.gov/pubmed/38236049 |
Collective effects of human genomic variation on microbiome function. | New FN, Baer BR, Clark AG, Wells MT, Brito IL | Scientific reports | 35264618 | Sci Rep | 2022 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/35264618 |
Functions predict horizontal gene transfer and the emergence of antibiotic resistance. | Zhou H, Beltrán JF, Brito IL | Science advances | 34678056 | Sci Adv | 2021 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/34678056 |
Linking plasmid-based beta-lactamases to their bacterial hosts using single-cell fusion PCR. | Diebold PJ, New FN, Hovan M, Satlin MJ, Brito IL | eLife | 34282723 | Elife | 2021 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/34282723 |
Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming. | Jones J, Shi Q, Nath RR, Brito IL | bioRxiv : the preprint server for biology | 37066368 | bioRxiv | 2023 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/37066368 |
Segatella clades adopt distinct roles within a single individual's gut. | Xiao X, Singh A, Giometto A, Brito IL | NPJ biofilms and microbiomes | 39465298 | NPJ Biofilms Microbiomes | 2024 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/39465298 |
Advances in genome editing through control of DNA repair pathways. | Yeh CD, Richardson CD, Corn JE | Nature cell biology | 31792376 | Nat Cell Biol | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31792376 |
A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation. | Liang JR, Lingeman E, Luong T, Ahmed S, Muhar M, Nguyen T, Olzmann JA, Corn JE | Cell | 32160526 | Cell | 2020 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/32160526 |
Genome editing to model and reverse a prevalent mutation associated with myeloproliferative neoplasms. | Baik R, Wyman SK, Kabir S, Corn JE | PloS one | 33661998 | PLoS One | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33661998 |
The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells. | Kabir S, Cidado J, Andersen C, Dick C, Lin PC, Mitros T, Ma H, Baik SH, Belmonte MA, Drew L, Corn JE | eLife | 31294695 | Elife | 2019 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/31294695 |
Double stranded DNA breaks and genome editing trigger loss of ribosomal protein RPS27A. | Riepe C, Zelin E, Frankino PA, Meacham ZA, Fernandez SG, Ingolia NT, Corn JE | The FEBS journal | 34914197 | FEBS J | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34914197 |
Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells. | Shin JJ, Schröder MS, Caiado F, Wyman SK, Bray NL, Bordi M, Dewitt MA, Vu JT, Kim WT, Hockemeyer D, Manz MG, Corn JE | Cell reports | 32877675 | Cell Rep | 2020 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/32877675 |
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq. | Wienert B, Wyman SK, Richardson CD, Yeh CD, Akcakaya P, Porritt MJ, Morlock M, Vu JT, Kazane KR, Watry HL, Judge LM, Conklin BR, Maresca M, Corn JE | Science (New York, N.Y.) | 31000663 | Science | 2019 Apr 19 | https://www.ncbi.nlm.nih.gov/pubmed/31000663 |
SLC19A1 transports immunoreactive cyclic dinucleotides. | Luteijn RD, Zaver SA, Gowen BG, Wyman SK, Garelis NE, Onia L, McWhirter SM, Katibah GE, Corn JE, Woodward JJ, Raulet DH | Nature | 31511694 | Nature | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31511694 |
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair. | Wienert B, Nguyen DN, Guenther A, Feng SJ, Locke MN, Wyman SK, Shin J, Kazane KR, Gregory GL, Carter MAM, Wright F, Conklin BR, Marson A, Richardson CD, Corn JE | Nature communications | 32355159 | Nat Commun | 2020 Apr 30 | https://www.ncbi.nlm.nih.gov/pubmed/32355159 |
In vitro-transcribed guide RNAs trigger an innate immune response via the RIG-I pathway. | Wienert B, Shin J, Zelin E, Pestal K, Corn JE | PLoS biology | 30011268 | PLoS Biol | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30011268 |
Atlastins remodel the endoplasmic reticulum for selective autophagy. | Liang JR, Lingeman E, Ahmed S, Corn JE | The Journal of cell biology | 30143524 | J Cell Biol | 2018 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/30143524 |
DENT-seq for genome-wide strand-specific identification of DNA single-strand break sites with single-nucleotide resolution. | Elacqua JJ, Ranu N, DiIorio SE, Blainey PC | Genome research | 33355294 | Genome Res | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33355294 |
Heterochromatin fidelity is a therapeutic vulnerability in lymphoma and other human cancers. | Najia MA, Jha DK, Zhang C, Laurent B, Kubaczka C, Markel A, Li C, Morris V, Tompkins A, Hensch L, Qin Y, Chapuy B, Huang YC, Morse M, Marunde MR, Vaidya A, Gillespie ZB, Howard SA, North TE, Dominguez D, Keogh MC, Schlaeger TM, Shi Y, Li H, Shipp MM, Blainey PC, Daley GQ | bioRxiv : the preprint server for biology | 39975048 | bioRxiv | 2025 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/39975048 |
Quantification of somatic mutation flow across individual cell division events by lineage sequencing. | Brody Y, Kimmerling RJ, Maruvka YE, Benjamin D, Elacqua JJ, Haradhvala NJ, Kim J, Mouw KW, Frangaj K, Koren A, Getz G, Manalis SR, Blainey PC | Genome research | 30459213 | Genome Res | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30459213 |
Programmable multi-kilobase RNA editing using CRISPR-mediated trans-splicing. | Borrajo J, Javanmardi K, Griffin J, St Martin SJ, Yao D, Hill K, Blainey PC, Al-Shayeb B | bioRxiv : the preprint server for biology | 37645763 | bioRxiv | 2023 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/37645763 |
CRISPResso2 provides accurate and rapid genome editing sequence analysis. | Clement K, Rees H, Canver MC, Gehrke JM, Farouni R, Hsu JY, Cole MA, Liu DR, Joung JK, Bauer DE, Pinello L | Nature biotechnology | 30809026 | Nat Biotechnol | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30809026 |
Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia. | Xu S, Luk K, Yao Q, Shen AH, Zeng J, Wu Y, Luo HY, Brendel C, Pinello L, Chui DHK, Wolfe SA, Bauer DE | Blood | 30704988 | Blood | 2019 May 23 | https://www.ncbi.nlm.nih.gov/pubmed/30704988 |
Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS. | Yamauchi T, Masuda T, Canver MC, Seiler M, Semba Y, Shboul M, Al-Raqad M, Maeda M, Schoonenberg VAC, Cole MA, Macias-Trevino C, Ishikawa Y, Yao Q, Nakano M, Arai F, Orkin SH, Reversade B, Buonamici S, Pinello L, Akashi K, Bauer DE, Maeda T | Cancer cell | 29478914 | Cancer Cell | 2018 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/29478914 |
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities. | Gehrke JM, Cervantes O, Clement MK, Wu Y, Zeng J, Bauer DE, Pinello L, Joung JK | Nature biotechnology | 30059493 | Nat Biotechnol | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30059493 |
Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits. | Choudhuri A, Trompouki E, Abraham BJ, Colli LM, Kock KH, Mallard W, Yang ML, Vinjamur DS, Ghamari A, Sporrij A, Hoi K, Hummel B, Boatman S, Chan V, Tseng S, Nandakumar SK, Yang S, Lichtig A, Superdock M, Grimes SN, Bowman TV, Zhou Y, Takahashi S, Joehanes R, Cantor AB, Bauer DE, Ganesh SK, Rinn J, Albert PS, Bulyk ML, Chanock SJ, Young RA, Zon LI | Nature genetics | 33230299 | Nat Genet | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33230299 |
Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci. | Canver MC, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern EN, Needleman AJ, Galactéros F, Brugnara C, Kutlar A, McKenzie C, Reid M, Chen DD, Das PP, A Cole M, Zeng J, Kurita R, Nakamura Y, Yuan GC, Lettre G, Bauer DE, Orkin SH | Nature genetics | 28218758 | Nat Genet | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/28218758 |
Functional interrogation of non-coding DNA through CRISPR genome editing. | Canver MC, Bauer DE, Orkin SH | Methods (San Diego, Calif.) | 28288828 | Methods | 2017 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/28288828 |
An erythroid-specific ATP2B4 enhancer mediates red blood cell hydration and malaria susceptibility. | Lessard S, Gatof ES, Beaudoin M, Schupp PG, Sher F, Ali A, Prehar S, Kurita R, Nakamura Y, Baena E, Ledoux J, Oceandy D, Bauer DE, Lettre G | The Journal of clinical investigation | 28714864 | J Clin Invest | 2017 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/28714864 |
Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis. | Sher F, Hossain M, Seruggia D, Schoonenberg VAC, Yao Q, Cifani P, Dassama LMK, Cole MA, Ren C, Vinjamur DS, Macias-Trevino C, Luk K, McGuckin C, Schupp PG, Canver MC, Kurita R, Nakamura Y, Fujiwara Y, Wolfe SA, Pinello L, Maeda T, Kentsis A, Orkin SH, Bauer DE | Nature genetics | 31253978 | Nat Genet | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31253978 |
CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis. | Schoonenberg VAC, Cole MA, Yao Q, Macias-Treviño C, Sher F, Schupp PG, Canver MC, Maeda T, Pinello L, Bauer DE | Genome biology | 30340514 | Genome Biol | 2018 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/30340514 |
Author Correction: Transcription factor competition at the γ-globin promoters controls hemoglobin switching. | Liu N, Xu S, Yao Q, Zhu Q, Kai Y, Hsu JY, Sakon P, Pinello L, Yuan GC, Bauer DE, Orkin SH | Nature genetics | 33731942 | Nat Genet | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33731942 |
Transcription factor competition at the γ-globin promoters controls hemoglobin switching. | Liu N, Xu S, Yao Q, Zhu Q, Kai Y, Hsu JY, Sakon P, Pinello L, Yuan GC, Bauer DE, Orkin SH | Nature genetics | 33649594 | Nat Genet | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33649594 |
Motif-Raptor: a cell type-specific and transcription factor centric approach for post-GWAS prioritization of causal regulators. | Yao Q, Ferragina P, Reshef Y, Lettre G, Bauer DE, Pinello L | Bioinformatics (Oxford, England) | 33532840 | Bioinformatics | 2021 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/33532840 |
ZNF410 represses fetal globin by singular control of CHD4. | Vinjamur DS, Yao Q, Cole MA, McGuckin C, Ren C, Zeng J, Hossain M, Luk K, Wolfe SA, Pinello L, Bauer DE | Nature genetics | 33859416 | Nat Genet | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33859416 |
Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. | Hu Y, Stilp AM, McHugh CP, Rao S, Jain D, Zheng X, Lane J, Méric de Bellefon S, Raffield LM, Chen MH, Yanek LR, Wheeler M, Yao Y, Ren C, Broome J, Moon JY, de Vries PS, Hobbs BD, Sun Q, Surendran P, Brody JA, Blackwell TW, Choquet H, Ryan K, Duggirala R, Heard-Costa N, Wang Z, Chami N, Preuss MH, Min N, Ekunwe L, Lange LA, Cushman M, Faraday N, Curran JE, Almasy L, Kundu K, Smith AV, Gabriel S, Rotter JI, Fornage M, Lloyd-Jones DM, Vasan RS, Smith NL, North KE, Boerwinkle E, Becker LC, Lewis JP, Abecasis GR, Hou L, O'Connell JR, Morrison AC, Beaty TH, Kaplan R, Correa A, Blangero J, Jorgenson E, Psaty BM, Kooperberg C, Walton RT, Kleinstiver BP, Tang H, Loos RJF, Soranzo N, Butterworth AS, Nickerson D, Rich SS, Mitchell BD, Johnson AD, Auer PL, Li Y, Mathias RA, Lettre G, Pankratz N, Laurie CC, Laurie CA, Bauer DE, Conomos MP, Reiner AP, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium | American journal of human genetics | 33887194 | Am J Hum Genet | 2021 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/33887194 |
Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency. | Wessels MW, Cnossen MH, van Dijk TB, Gillemans N, Schmidt KLJ, van Lom K, Vinjamur DS, Coyne S, Kurita R, Nakamura Y, de Man SA, Pfundt R, Azmani Z, Brouwer RWW, Bauer DE, van den Hout MCGN, van IJcken WFJ, Philipsen S | Blood advances | 33938942 | Blood Adv | 2021 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/33938942 |
Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program. | Wheeler MM, Stilp AM, Rao S, Halldórsson BV, Beyter D, Wen J, Mihkaylova AV, McHugh CP, Lane J, Jiang MZ, Raffield LM, Jun G, Sedlazeck FJ, Metcalf G, Yao Y, Bis JB, Chami N, de Vries PS, Desai P, Floyd JS, Gao Y, Kammers K, Kim W, Moon JY, Ratan A, Yanek LR, Almasy L, Becker LC, Blangero J, Cho MH, Curran JE, Fornage M, Kaplan RC, Lewis JP, Loos RJF, Mitchell BD, Morrison AC, Preuss M, Psaty BM, Rich SS, Rotter JI, Tang H, Tracy RP, Boerwinkle E, Abecasis GR, Blackwell TW, Smith AV, Johnson AD, Mathias RA, Nickerson DA, Conomos MP, Li Y, Þorsteinsdóttir U, Magnússon MK, Stefansson K, Pankratz ND, Bauer DE, Auer PL, Reiner AP | Nature communications | 36481753 | Nat Commun | 2022 Dec 8 | https://www.ncbi.nlm.nih.gov/pubmed/36481753 |
Technical considerations for the use of CRISPR/Cas9 in hematology research. | Gundry MC, Dever DP, Yudovich D, Bauer DE, Haas S, Wilkinson AC, Singbrant S | Experimental hematology | 28757433 | Exp Hematol | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28757433 |
DrugThatGene: integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens. | Canver MC, Bauer DE, Maeda T, Pinello L | Bioinformatics (Oxford, England) | 30395160 | Bioinformatics | 2019 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/30395160 |
Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation. | Rao S, Yao Y, Bauer DE | Genome medicine | 33691767 | Genome Med | 2021 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/33691767 |
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data. | Hsu JY, Fulco CP, Cole MA, Canver MC, Pellin D, Sher F, Farouni R, Clement K, Guo JA, Biasco L, Orkin SH, Engreitz JM, Lander ES, Joung JK, Bauer DE, Pinello L | Nature methods | 30504875 | Nat Methods | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30504875 |
AmpUMI: design and analysis of unique molecular identifiers for deep amplicon sequencing. | Clement K, Farouni R, Bauer DE, Pinello L | Bioinformatics (Oxford, England) | 29949956 | Bioinformatics | 2018 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/29949956 |
14q32 and let-7 microRNAs regulate transcriptional networks in fetal and adult human erythroblasts. | Lessard S, Beaudoin M, Orkin SH, Bauer DE, Lettre G | Human molecular genetics | 29432581 | Hum Mol Genet | 2018 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/29432581 |
Highly efficient therapeutic gene editing of human hematopoietic stem cells. | Wu Y, Zeng J, Roscoe BP, Liu P, Yao Q, Lazzarotto CR, Clement K, Cole MA, Luk K, Baricordi C, Shen AH, Ren C, Esrick EB, Manis JP, Dorfman DM, Williams DA, Biffi A, Brugnara C, Biasco L, Brendel C, Pinello L, Tsai SQ, Wolfe SA, Bauer DE | Nature medicine | 30911135 | Nat Med | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30911135 |
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM. | Chen H, Albergante L, Hsu JY, Lareau CA, Lo Bosco G, Guan J, Zhou S, Gorban AN, Bauer DE, Aryee MJ, Langenau DM, Zinovyev A, Buenrostro JD, Yuan GC, Pinello L | Nature communications | 31015418 | Nat Commun | 2019 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/31015418 |
Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells. | Nagpal N, Wang J, Zeng J, Lo E, Moon DH, Luk K, Braun RO, Burroughs LM, Keel SB, Reilly C, Lindsley RC, Wolfe SA, Tai AK, Cahan P, Bauer DE, Fong YW, Agarwal S | Cell stem cell | 32320679 | Cell Stem Cell | 2020 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/32320679 |
A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and Their Differentiated Derivatives. | El-Nachef D, Shi K, Beussman KM, Martinez R, Regier MC, Everett GW, Murry CE, Stevens KR, Young JE, Sniadecki NJ, Davis J | Stem cell reports | 32619493 | Stem Cell Reports | 2020 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/32619493 |
Human Pluripotent Stem Cell-Derived Engineered Tissues: Clinical Considerations. | Stevens KR, Murry CE | Cell stem cell | 29499147 | Cell Stem Cell | 2018 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/29499147 |
Guided vascularization in the rat heart leads to transient vessel patterning. | Brady EL, Kirby MA, Olszewski E, Grosjean P, Johansson F, Davis J, Wang RK, Stevens KR | APL bioengineering | 32161835 | APL Bioeng | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32161835 |
Photopatterned biomolecule immobilization to guide three-dimensional cell fate in natural protein-based hydrogels. | Batalov I, Stevens KR, DeForest CA | Proceedings of the National Academy of Sciences of the United States of America | 33468675 | Proc Natl Acad Sci U S A | 2021 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/33468675 |
User-defined morphogen patterning for directing human cell fate stratification. | Regier MC, Tokar JJ, Warrick JW, Pabon L, Berthier E, Beebe DJ, Stevens KR | Scientific reports | 31015521 | Sci Rep | 2019 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/31015521 |
Author Correction: Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates. | Kinstlinger IS, Saxton SH, Calderon GA, Ruiz KV, Yalacki DR, Deme PR, Rosenkrantz JE, Louis-Rosenberg JD, Johansson F, Janson KD, Sazer DW, Panchavati SS, Bissig KD, Stevens KR, Miller JS | Nature biomedical engineering | 34135476 | Nat Biomed Eng | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34135476 |
A FRESH Take on Resolution in 3D Bioprinting. | Corbett DC, Olszewski E, Stevens K | Trends in biotechnology | 31623960 | Trends Biotechnol | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31623960 |
Infarct Collagen Topography Regulates Fibroblast Fate via p38-Yes-Associated Protein Transcriptional Enhanced Associate Domain Signals. | Bugg D, Bretherton R, Kim P, Olszewski E, Nagle A, Schumacher AE, Chu N, Gunaje J, DeForest CA, Stevens K, Kim DH, Davis J | Circulation research | 32883176 | Circ Res | 2020 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/32883176 |
Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates. | Kinstlinger IS, Saxton SH, Calderon GA, Ruiz KV, Yalacki DR, Deme PR, Rosenkrantz JE, Louis-Rosenberg JD, Johansson F, Janson KD, Sazer DW, Panchavati SS, Bissig KD, Stevens KR, Miller JS | Nature biomedical engineering | 32601395 | Nat Biomed Eng | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32601395 |
Embryo-scale, single-cell spatial transcriptomics. | Srivatsan SR, Regier MC, Barkan E, Franks JM, Packer JS, Grosjean P, Duran M, Saxton S, Ladd JJ, Spielmann M, Lois C, Lampe PD, Shendure J, Stevens KR, Trapnell C | Science (New York, N.Y.) | 34210887 | Science | 2021 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/34210887 |
Engineered tissue vascularization and engraftment depends on host model. | Brady EL, Prado O, Johansson F, Mitchell SN, Martinson AM, Karbassi E, Reinecke H, Murry CE, Davis J, Stevens KR | Scientific reports | 36737618 | Sci Rep | 2023 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/36737618 |
Thermofluidic heat exchangers for actuation of transcription in artificial tissues. | Corbett DC, Fabyan WB, Grigoryan B, O'Connor CE, Johansson F, Batalov I, Regier MC, DeForest CA, Miller JS, Stevens KR | Science advances | 32998880 | Sci Adv | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32998880 |
Spatial presentation of biological molecules to cells by localized diffusive transfer. | Regier MC, Olszewski E, Carter CC, Aitchison JD, Kaushansky A, Davis J, Berthier E, Beebe DJ, Stevens KR | Lab on a chip | 31111131 | Lab Chip | 2019 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/31111131 |
Multivascular networks and functional intravascular topologies within biocompatible hydrogels. | Grigoryan B, Paulsen SJ, Corbett DC, Sazer DW, Fortin CL, Zaita AJ, Greenfield PT, Calafat NJ, Gounley JP, Ta AH, Johansson F, Randles A, Rosenkrantz JE, Louis-Rosenberg JD, Galie PA, Stevens KR, Miller JS | Science (New York, N.Y.) | 31048486 | Science | 2019 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/31048486 |
Human Organ-Specific Endothelial Cell Heterogeneity. | Marcu R, Choi YJ, Xue J, Fortin CL, Wang Y, Nagao RJ, Xu J, MacDonald JW, Bammler TK, Murry CE, Muczynski K, Stevens KR, Himmelfarb J, Schwartz SM, Zheng Y | iScience | 30240741 | iScience | 2018 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/30240741 |
Engineering Heart Morphogenesis. | Mandrycky CJ, Williams NP, Batalov I, El-Nachef D, de Bakker BS, Davis J, Kim DH, DeForest CA, Zheng Y, Stevens KR, Sniadecki NJ | Trends in biotechnology | 32673587 | Trends Biotechnol | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32673587 |
Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions. | Lemaster JE, Jeevarathinam AS, Kumar A, Chandrasekar B, Chen F, Jokerst JV | ACS applied bio materials | 31930189 | ACS Appl Bio Mater | 2019 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/31930189 |
Increasing the Efficacy of Stem Cell Therapy via Triple-Function Inorganic Nanoparticles. | Chen F, Zhao ER, Hableel G, Hu T, Kim T, Li J, Gonzalez-Pech NI, Cheng DJ, Lemaster JE, Xie Y, Grassian VH, Sen GL, Jokerst JV | ACS nano | 31188564 | ACS Nano | 2019 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/31188564 |
The characterization of an economic and portable LED-based photoacoustic imaging system to facilitate molecular imaging. | Hariri A, Lemaster J, Wang J, Jeevarathinam AS, Chao DL, Jokerst JV | Photoacoustics | 29234601 | Photoacoustics | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29234601 |
Photoacoustic Imaging for Noninvasive Periodontal Probing Depth Measurements. | Lin CY, Chen F, Hariri A, Chen CJ, Wilder-Smith P, Takesh T, Jokerst JV | Journal of dental research | 28880116 | J Dent Res | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28880116 |
Deep learning improves contrast in low-fluence photoacoustic imaging. | Hariri A, Alipour K, Mantri Y, Schulze JP, Jokerst JV | Biomedical optics express | 32637260 | Biomed Opt Express | 2020 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/32637260 |
Phenolic-enabled nanotechnology: versatile particle engineering for biomedicine. | Wu D , Zhou J , Creyer MN , Yim W , Chen Z , Messersmith PB , Jokerst JV | Chemical Society reviews | 33595004 | Chem Soc Rev | 2021 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/33595004 |
Enhanced Photoacoustic Detection of Heparin in Whole Blood via Melanin Nanocapsules Carrying Molecular Agents. | Yim W, Takemura K, Zhou J, Zhou J, Jin Z, Borum RM, Xu M, Cheng Y, He T, Penny W, Miller BR 3rd, Jokerst JV | ACS nano | 34962765 | ACS Nano | 2022 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/34962765 |
A Photoacoustic Contrast Agent for miR-21 via NIR Fluorescent Hybridization Chain Reaction. | Borum RM, Moore C, Chan SK, Steinmetz NF, Jokerst JV | Bioconjugate chemistry | 34406744 | Bioconjug Chem | 2022 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/34406744 |
Photoacoustic Imaging of Human Mesenchymal Stem Cells Labeled with Prussian Blue-Poly(l-lysine) Nanocomplexes. | Kim T, Lemaster JE, Chen F, Li J, Jokerst JV | ACS nano | 28759195 | ACS Nano | 2017 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/28759195 |
A cellulose-based photoacoustic sensor to measure heparin concentration and activity in human blood samples. | Jeevarathinam AS, Pai N, Huang K, Hariri A, Wang J, Bai Y, Wang L, Hancock T, Keys S, Penny W, Jokerst JV | Biosensors & bioelectronics | 30602265 | Biosens Bioelectron | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30602265 |
Hybridizing clinical translatability with enzyme-free DNA signal amplifiers: recent advances in nucleic acid detection and imaging. | Borum RM , Jokerst JV | Biomaterials science | 32734995 | Biomater Sci | 2021 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/32734995 |
Organosilica Nanoparticles with an Intrinsic Secondary Amine: An Efficient and Reusable Adsorbent for Dyes. | Chen F, Zhao E, Kim T, Wang J, Hableel G, Reardon PJT, Ananthakrishna SJ, Wang T, Arconada-Alvarez S, Knowles JC, Jokerst JV | ACS applied materials & interfaces | 28422482 | ACS Appl Mater Interfaces | 2017 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/28422482 |
In vivo photoacoustic imaging of chorioretinal oxygen gradients. | Hariri A, Wang J, Kim Y, Jhunjhunwala A, Chao DL, Jokerst JV | Journal of biomedical optics | 29524321 | J Biomed Opt | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29524321 |
Switchable Photoacoustic Intensity of Methylene Blue via Sodium Dodecyl Sulfate Micellization. | Wang J, Lin CY, Moore C, Jhunjhunwala A, Jokerst JV | Langmuir : the ACS journal of surfaces and colloids | 29232146 | Langmuir | 2018 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/29232146 |
Listening for the therapeutic window: Advances in drug delivery utilizing photoacoustic imaging. | Moore C, Chen F, Wang J, Jokerst JV | Advanced drug delivery reviews | 31295522 | Adv Drug Deliv Rev | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31295522 |
Cellular toxicity of silicon carbide nanomaterials as a function of morphology. | Chen F, Li G, Zhao ER, Li J, Hableel G, Lemaster JE, Bai Y, Sen GL, Jokerst JV | Biomaterials | 29980075 | Biomaterials | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29980075 |
Versatile Polymer Nanocapsules via Redox Competition. | Zhou J, Xu M, Jin Z, Borum RM, Avakyan N, Cheng Y, Yim W, He T, Zhou J, Wu Z, Mantri Y, Jokerst JV | Angewandte Chemie (International ed. in English) | 34580967 | Angew Chem Int Ed Engl | 2021 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/34580967 |
The in vivo fate of tobacco mosaic virus nanoparticle theranostic agents modified by the addition of a polydopamine coat. | Nkanga CI, Chung YH, Shukla S, Zhou J, Jokerst JV, Steinmetz NF | Biomaterials science | 34591046 | Biomater Sci | 2021 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/34591046 |
Motion-compensated noninvasive periodontal health monitoring using handheld and motor-based photoacoustic-ultrasound imaging systems. | Mozaffarzadeh M, Moore C, Golmoghani EB, Mantri Y, Hariri A, Jorns A, Fu L, Verweij MD, Orooji M, de Jong N, Jokerst JV | Biomedical optics express | 33796371 | Biomed Opt Express | 2021 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/33796371 |
Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity. | Moore C, Borum RM, Mantri Y, Xu M, Fajtová P, O'Donoghue AJ, Jokerst JV | ACS sensors | 34038103 | ACS Sens | 2021 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/34038103 |
Stereoselective Growth of Small Molecule Patches on Nanoparticles. | Zhou J, Creyer MN, Chen A, Yim W, Lafleur RPM, He T, Lin Z, Xu M, Abbasi P, Wu J, Pascal TA, Caruso F, Jokerst JV | Journal of the American Chemical Society | 34270250 | J Am Chem Soc | 2021 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/34270250 |
Ultrasmall gold nanorod-polydopamine hybrids for enhanced photoacoustic imaging and photothermal therapy in second near-infrared window. | Yim W, Borum RM, Zhou J, Mantri Y, Wu Z, Zhou J, Jin Z, Creyer M, Jokerst JV | Nanotheranostics | 34976582 | Nanotheranostics | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/34976582 |
Copper Sulfide Nanodisks and Nanoprisms for Photoacoustic Ovarian Tumor Imaging. | Wang J, Hsu SW, Gonzalez-Pech N, Jhunjhunwala A, Chen F, Hariri A, Grassian V, Tao A, Jokerst JV | Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems | 32863594 | Part Part Syst Charact | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32863594 |
Assessment of Respiratory Droplet Transmission During the Ophthalmic Slit-Lamp Exam: A Particle Tracking Analysis. | Shah SH, Garg AK, Patel S, Yim W, Jokerst JV, Chao DL | American journal of ophthalmology | 32980331 | Am J Ophthalmol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32980331 |
Assessing the Physiological Relevance of Cough Simulators for Respiratory Droplet Dispersion. | Patel SH, Yim W, Garg AK, Shah SH, Jokerst JV, Chao DL | Journal of clinical medicine | 32957639 | J Clin Med | 2020 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/32957639 |
Silicon Carbide Nanoparticles as a Photoacoustic and Photoluminescent Dual-Imaging Contrast Agent for Long-Term Cell Tracking. | Chen F, Zhao ER, Hu T, Shi Y, Sirbuly DJ, Jokerst JV | Nanoscale advances | 33313479 | Nanoscale Adv | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/33313479 |
A Photoacoustic-Fluorescent Imaging Probe for Proteolytic Gingipains Expressed by Porphyromonas gingivalis. | Moore C, Cheng Y, Tjokro N, Zhang B, Kerr M, Hayati M, Chang KCJ, Shah N, Chen C, Jokerst JV | Angewandte Chemie (International ed. in English) | 35583940 | Angew Chem Int Ed Engl | 2022 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/35583940 |
Dictionary learning technique enhances signal in LED-based photoacoustic imaging. | Farnia P, Najafzadeh E, Hariri A, Lavasani SN, Makkiabadi B, Ahmadian A, Jokerst JV | Biomedical optics express | 32499941 | Biomed Opt Express | 2020 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/32499941 |
Iodide-doped precious metal nanoparticles: measuring oxidative stress in vivo via photoacoustic imaging. | Mantri Y, Davidi B, Lemaster JE, Hariri A, Jokerst JV | Nanoscale | 32396928 | Nanoscale | 2020 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/32396928 |
A Gold/Silver Hybrid Nanoparticle for Treatment and Photoacoustic Imaging of Bacterial Infection. | Kim T, Zhang Q, Li J, Zhang L, Jokerst JV | ACS nano | 29746090 | ACS Nano | 2018 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/29746090 |
Peptide-Induced Fractal Assembly of Silver Nanoparticles for Visual Detection of Disease Biomarkers. | Retout M, Mantri Y, Jin Z, Zhou J, Noël G, Donovan B, Yim W, Jokerst JV | ACS nano | 35377141 | ACS Nano | 2022 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/35377141 |
Synchronization of RF Data in Ultrasound Open Platforms (UOPs) for High-Accuracy and High-Resolution Photoacoustic Tomography Using the "Scissors" Programming Method. | Fu L, Jin Z, Qi B, Yim W, Wu Z, He T, Jokerst JV | IEEE transactions on ultrasonics, ferroelectrics, and frequency control | 35377843 | IEEE Trans Ultrason Ferroelectr Freq Control | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35377843 |
Gold nanoparticles to enhance ophthalmic imaging. | Chen F , Si P , de la Zerda A , Jokerst JV , Myung D | Biomaterials science | 33057463 | Biomater Sci | 2021 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/33057463 |
KN95 and N95 Respirators Retain Filtration Efficiency despite a Loss of Dipole Charge during Decontamination. | Yim W, Cheng D, Patel SH, Kou R, Meng YS, Jokerst JV | ACS applied materials & interfaces | 33253527 | ACS Appl Mater Interfaces | 2020 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/33253527 |
A fiber optic photoacoustic sensor for real-time heparin monitoring. | Zhou J, Yim W, Zhou J, Jin Z, Xu M, Mantri Y, He T, Cheng Y, Fu L, Wu Z, Hancock T, Penny W, Jokerst JV | Biosensors & bioelectronics | 34653712 | Biosens Bioelectron | 2022 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/34653712 |
A Wearable Colorimetric Dosimeter to Monitor Sunlight Exposure. | Wang J, Jeevarathinam AS, Jhunjhunwala A, Ren H, Lemaster J, Luo Y, Fenning DP, Fullerton EE, Jokerst JV | Advanced materials technologies | 33928184 | Adv Mater Technol | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33928184 |
Photoacoustic imaging with fiber optic technology: A review. | Zhou J, Jokerst JV | Photoacoustics | 33163358 | Photoacoustics | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33163358 |
Exosome-like silica nanoparticles: a novel ultrasound contrast agent for stem cell imaging. | Chen F, Ma M, Wang J, Wang F, Chern SX, Zhao ER, Jhunjhunwala A, Darmadi S, Chen H, Jokerst JV | Nanoscale | 27924340 | Nanoscale | 2017 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/27924340 |
Gold Nanorod-Melanin Hybrids for Enhanced and Prolonged Photoacoustic Imaging in the Near-Infrared-II Window. | Yim W, Zhou J, Mantri Y, Creyer MN, Moore CA, Jokerst JV | ACS applied materials & interfaces | 33761255 | ACS Appl Mater Interfaces | 2021 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/33761255 |
Gadolinium Doping Enhances the Photoacoustic Signal of Synthetic Melanin Nanoparticles: A Dual Modality Contrast Agent for Stem Cell Imaging. | Lemaster JE, Wang Z, Hariri A, Chen F, Hu Z, Huang Y, Barback CV, Cochran R, Gianneschi NC, Jokerst JV | Chemistry of materials : a publication of the American Chemical Society | 33859455 | Chem Mater | 2019 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/33859455 |
Simultaneous Enhancement of Photoluminescence, MRI Relaxivity, and CT Contrast by Tuning the Interfacial Layer of Lanthanide Heteroepitaxial Nanoparticles. | He S, Johnson NJJ, Nguyen Huu VA, Cory E, Huang Y, Sah RL, Jokerst JV, Almutairi A | Nano letters | 28657755 | Nano Lett | 2017 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/28657755 |
Polyphenol-stabilized coacervates for enzyme-triggered drug delivery. | Yim W, Jin Z, Chang YC, Brambila C, Creyer MN, Ling C, He T, Li Y, Retout M, Penny WF, Zhou J, Jokerst JV | Nature communications | 39181884 | Nat Commun | 2024 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/39181884 |
Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system. | Hariri A, Zhao E, Jeevarathinam AS, Lemaster J, Zhang J, Jokerst JV | Scientific reports | 31388020 | Sci Rep | 2019 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/31388020 |
Tuning the ultrasonic and photoacoustic response of polydopamine-stabilized perfluorocarbon contrast agents. | Xie Y, Wang J, Wang J, Hu Z, Hariri A, Tu N, Krug KA, Burkart MD, Gianneschi NC, Jokerst JV, Rinehart JD | Journal of materials chemistry. B | 31389967 | J Mater Chem B | 2019 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/31389967 |
A Nanoscale Tool for Photoacoustic-Based Measurements of Clotting Time and Therapeutic Drug Monitoring of Heparin. | Wang J, Chen F, Arconada-Alvarez SJ, Hartanto J, Yap LP, Park R, Wang F, Vorobyova I, Dagliyan G, Conti PS, Jokerst JV | Nano letters | 27668964 | Nano Lett | 2016 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/27668964 |
The development and characterization of a novel yet simple 3D printed tool to facilitate phantom imaging of photoacoustic contrast agents. | Arconada-Alvarez SJ, Lemaster JE, Wang J, Jokerst JV | Photoacoustics | 28239554 | Photoacoustics | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28239554 |
Development of a Trimodal Contrast Agent for Acoustic and Magnetic Particle Imaging of Stem Cells. | Lemaster JE, Chen F, Kim T, Hariri A, Jokerst JV | ACS applied nano materials | 33860154 | ACS Appl Nano Mater | 2018 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/33860154 |
Smart-Dust-Nanorice for Enhancement of Endogenous Raman Signal, Contrast in Photoacoustic Imaging, and T2-Shortening in Magnetic Resonance Imaging. | Pohling C, Campbell JL, Larson TA, Van de Sompel D, Levi J, Bachmann MH, Bohndiek SE, Jokerst JV, Gambhir SS | Small (Weinheim an der Bergstrasse, Germany) | 29635739 | Small | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29635739 |
A Mechanistic Investigation of Methylene Blue and Heparin Interactions and Their Photoacoustic Enhancement. | Wang J, Jeevarathinam AS, Humphries K, Jhunjhunwala A, Chen F, Hariri A, Miller BR 3rd, Jokerst JV | Bioconjugate chemistry | 30281976 | Bioconjug Chem | 2018 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/30281976 |
Optics-Free, Non-Contact Measurements of Fluids, Bubbles, and Particles in Microchannels Using Metallic Nano-Islands on Graphene. | Dhong C, Edmunds SJ, Ramírez J, Kayser LV, Chen F, Jokerst JV, Lipomi DJ | Nano letters | 30024767 | Nano Lett | 2018 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/30024767 |
Multifunctional nanomedicine with silica: Role of silica in nanoparticles for theranostic, imaging, and drug monitoring. | Chen F, Hableel G, Zhao ER, Jokerst JV | Journal of colloid and interface science | 29510868 | J Colloid Interface Sci | 2018 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/29510868 |
Noninvasive staging of pressure ulcers using photoacoustic imaging. | Hariri A, Chen F, Moore C, Jokerst JV | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society | 31301258 | Wound Repair Regen | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31301258 |
Photoacoustic Imaging Quantifies Drug Release from Nanocarriers via Redox Chemistry of Dye-Labeled Cargo. | Jeevarathinam AS, Lemaster JE, Chen F, Zhao E, Jokerst JV | Angewandte Chemie (International ed. in English) | 31840357 | Angew Chem Int Ed Engl | 2020 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/31840357 |
Enhanced Performance of a Molecular Photoacoustic Imaging Agent by Encapsulation in Mesoporous Silicon Nanoparticles. | Kang J, Kim D, Wang J, Han Y, Zuidema JM, Hariri A, Park JH, Jokerst JV, Sailor MJ | Advanced materials (Deerfield Beach, Fla.) | 29782671 | Adv Mater | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29782671 |
Photoacoustic imaging for monitoring periodontal health: A first human study. | Moore C, Bai Y, Hariri A, Sanchez JB, Lin CY, Koka S, Sedghizadeh P, Chen C, Jokerst JV | Photoacoustics | 30450281 | Photoacoustics | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30450281 |
Strategies for Image-Guided Therapy, Surgery, and Drug Delivery Using Photoacoustic Imaging. | Moore C, Jokerst JV | Theranostics | 31037123 | Theranostics | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31037123 |
Multispectral Nanoparticle Tracking Analysis for the Real-Time and Label-Free Characterization of Amyloid-β Self-Assembly In Vitro. | Moore C, Wing R, Pham T, Jokerst JV | Analytical chemistry | 32786456 | Anal Chem | 2020 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/32786456 |
Stem Cell Tracking with Nanoparticle-Based Ultrasound Contrast Agents. | Chen F, Jokerst JV | Methods in molecular biology (Clifton, N.J.) | 32112386 | Methods Mol Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32112386 |
Engineering Plasmonic Nanoparticles for Enhanced Photoacoustic Imaging. | Mantri Y, Jokerst JV | ACS nano | 32806027 | ACS Nano | 2020 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/32806027 |
A Protease-Responsive Polymer/Peptide Conjugate and Reversible Assembly of Silver Clusters for the Detection of Porphyromonas gingivalis Enzymatic Activity. | Retout M, Amer L, Yim W, Creyer MN, Lam B, Trujillo DF, Potempa J, O'Donoghue AJ, Chen C, Jokerst JV | ACS nano | 37602819 | ACS Nano | 2023 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/37602819 |
Robust and Versatile Coatings Engineered via Simultaneous Covalent and Noncovalent Interactions. | Zhou J, Penna M, Lin Z, Han Y, Lafleur RPM, Qu Y, Richardson JJ, Yarovsky I, Jokerst JV, Caruso F | Angewandte Chemie (International ed. in English) | 34258845 | Angew Chem Int Ed Engl | 2021 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/34258845 |
Supramolecular Loading of DNA Hydrogels with Dye-Drug Conjugates for Real-Time Photoacoustic Monitoring of Chemotherapy. | Borum RM, Moore C, Mantri Y, Xu M, Jokerst JV | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 36403233 | Adv Sci (Weinh) | 2022 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/36403233 |
Cryo-electron tomography with mixed-scale dense neural networks reveals key steps in deployment of Toxoplasma invasion machinery. | Segev-Zarko LA, Dahlberg PD, Sun SY, Pelt DM, Kim CY, Egan ES, Sethian JA, Chiu W, Boothroyd JC | PNAS nexus | 36329726 | PNAS Nexus | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36329726 |
Cryogenic electron tomography reveals novel structures in the apical complex of Plasmodium falciparum. | Sun SY, Segev-Zarko L-a, Pintilie GD, Kim CY, Staggers SR, Schmid MF, Egan ES, Chiu W, Boothroyd JC | mBio | 38456679 | mBio | 2024 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/38456679 |
A common polymorphism in the mechanosensitive ion channel PIEZO1 is associated with protection from severe malaria in humans. | Nguetse CN, Purington N, Ebel ER, Shakya B, Tetard M, Kremsner PG, Velavan TP, Egan ES | Proceedings of the National Academy of Sciences of the United States of America | 32265284 | Proc Natl Acad Sci U S A | 2020 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/32265284 |
Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasion. | Baro B, Kim CY, Lin C, Kongsomboonvech AK, Tetard M, Peterson NA, Salinas ND, Tolia NH, Egan ES | Blood | 37832027 | Blood | 2023 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/37832027 |
Erythrocyte CD55 mediates the internalization of Plasmodium falciparum parasites. | Shakya B, Patel SD, Tani Y, Egan ES | eLife | 34028351 | Elife | 2021 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/34028351 |
Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum. | Egan ES, Weekes MP, Kanjee U, Manzo J, Srinivasan A, Lomas-Francis C, Westhoff C, Takahashi J, Tanaka M, Watanabe S, Brugnara C, Gygi SP, Tani Y, Duraisingh MT | Communications biology | 30271928 | Commun Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30271928 |
Beyond Hemoglobin: Screening for Malaria Host Factors. | Egan ES | Trends in genetics : TIG | 29249333 | Trends Genet | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29249333 |
Uncovering a Cryptic Site of Malaria Pathogenesis: Models to Study Interactions Between Plasmodium and the Bone Marrow. | Feldman TP, Egan ES | Frontiers in cellular and infection microbiology | 35719356 | Front Cell Infect Microbiol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35719356 |
Revisiting the malaria hypothesis: accounting for polygenicity and pleiotropy. | Ebel ER, Uricchio LH, Petrov DA, Egan ES | Trends in parasitology | 35065882 | Trends Parasitol | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35065882 |
CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion. | Mou H, Smith JL, Peng L, Yin H, Moore J, Zhang XO, Song CQ, Sheel A, Wu Q, Ozata DM, Li Y, Anderson DG, Emerson CP, Sontheimer EJ, Moore MJ, Weng Z, Xue W | Genome biology | 28615073 | Genome Biol | 2017 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/28615073 |
Depletion of TRRAP Induces p53-Independent Senescence in Liver Cancer by Down-Regulating Mitotic Genes. | Kwan SY, Sheel A, Song CQ, Zhang XO, Jiang T, Dang H, Cao Y, Ozata DM, Mou H, Yin H, Weng Z, Wang XW, Xue W | Hepatology (Baltimore, Md.) | 31188495 | Hepatology | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31188495 |
A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver. | Zheng C, Liang SQ, Liu B, Liu P, Kwan SY, Wolfe SA, Xue W | Molecular therapy : the journal of the American Society of Gene Therapy | 34998953 | Mol Ther | 2022 Mar 2 | https://www.ncbi.nlm.nih.gov/pubmed/34998953 |
A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing. | Edraki A, Mir A, Ibraheim R, Gainetdinov I, Yoon Y, Song CQ, Cao Y, Gallant J, Xue W, Rivera-Pérez JA, Sontheimer EJ | Molecular cell | 30581144 | Mol Cell | 2019 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/30581144 |
In Vivo Genome Editing Partially Restores Alpha1-Antitrypsin in a Murine Model of AAT Deficiency. | Song CQ, Wang D, Jiang T, O'Connor K, Tang Q, Cai L, Li X, Weng Z, Yin H, Gao G, Mueller C, Flotte TR, Xue W | Human gene therapy | 29597895 | Hum Gene Ther | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29597895 |
Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function. | Jiang T, Sánchez-Rivera FJ, Soto-Feliciano YM, Yang Q, Song CQ, Bhuatkar A, Haynes CM, Hemann MT, Xue W | Hepatology (Baltimore, Md.) | 33336367 | Hepatology | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33336367 |
Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice. | Song CQ, Li Y, Mou H, Moore J, Park A, Pomyen Y, Hough S, Kennedy Z, Fischer A, Yin H, Anderson DG, Conte D Jr, Zender L, Wang XW, Thorgeirsson S, Weng Z, Xue W | Gastroenterology | 27956228 | Gastroenterology | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/27956228 |
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity. | Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG | Nature chemical biology | 29377001 | Nat Chem Biol | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29377001 |
CRISPR-Cas-related technologies in basic and translational liver research. | Song CQ, Xue W | Nature reviews. Gastroenterology & hepatology | 29443117 | Nat Rev Gastroenterol Hepatol | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29443117 |
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice. | Wang D, Li J, Song CQ, Tran K, Mou H, Wu PH, Tai PWL, Mendonca CA, Ren L, Wang BY, Su Q, Gessler DJ, Zamore PD, Xue W, Gao G | Nature biotechnology | 30102296 | Nat Biotechnol | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30102296 |
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo. | Ibraheim R, Tai PWL, Mir A, Javeed N, Wang J, Rodríguez TC, Namkung S, Nelson S, Khokhar ES, Mintzer E, Maitland S, Chen Z, Cao Y, Tsagkaraki E, Wolfe SA, Wang D, Pai AA, Xue W, Gao G, Sontheimer EJ | Nature communications | 34725353 | Nat Commun | 2021 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/34725353 |
Genome-wide detection of CRISPR editing in vivo using GUIDE-tag. | Liang SQ, Liu P, Smith JL, Mintzer E, Maitland S, Dong X, Yang Q, Lee J, Haynes CM, Zhu LJ, Watts JK, Sontheimer EJ, Wolfe SA, Xue W | Nature communications | 35064134 | Nat Commun | 2022 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/35064134 |
CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling. | Mou H, Ozata DM, Smith JL, Sheel A, Kwan SY, Hough S, Kucukural A, Kennedy Z, Cao Y, Xue W | Genome medicine | 30987660 | Genome Med | 2019 Apr 16 | https://www.ncbi.nlm.nih.gov/pubmed/30987660 |
Multiomics characterization of mouse hepatoblastoma identifies yes-associated protein 1 target genes. | Rodríguez TC, Kwan SY, Smith JL, Dadafarin S, Wu CH, Sontheimer EJ, Xue W | Hepatology (Baltimore, Md.) | 35932276 | Hepatology | 2023 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/35932276 |
Adenine base editing in an adult mouse model of tyrosinaemia. | Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W | Nature biomedical engineering | 31740768 | Nat Biomed Eng | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31740768 |
Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope. | Jiang T, Henderson JM, Coote K, Cheng Y, Valley HC, Zhang XO, Wang Q, Rhym LH, Cao Y, Newby GA, Bihler H, Mense M, Weng Z, Anderson DG, McCaffrey AP, Liu DR, Xue W | Nature communications | 32332735 | Nat Commun | 2020 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/32332735 |
Deletion and replacement of long genomic sequences using prime editing. | Jiang T, Zhang XO, Weng Z, Xue W | Nature biotechnology | 34650270 | Nat Biotechnol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34650270 |
Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag. | Liang SQ, Liu P, Ponnienselvan K, Suresh S, Chen Z, Kramme C, Chatterjee P, Zhu LJ, Sontheimer EJ, Xue W, Wolfe SA | Nature methods | 37156841 | Nat Methods | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37156841 |
YAP1 Withdrawal in Hepatoblastoma Drives Therapeutic Differentiation of Tumor Cells to Functional Hepatocyte-Like Cells. | Smith JL, Rodríguez TC, Mou H, Kwan SY, Pratt H, Zhang XO, Cao Y, Liang S, Ozata DM, Yu T, Yin Q, Hazeltine M, Weng Z, Sontheimer EJ, Xue W | Hepatology (Baltimore, Md.) | 32452550 | Hepatology | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32452550 |
The temporal landscape of recursive splicing during Pol II transcription elongation in human cells. | Zhang XO, Fu Y, Mou H, Xue W, Weng Z | PLoS genetics | 30148885 | PLoS Genet | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30148885 |
A split prime editor with untethered reverse transcriptase and circular RNA template. | Liu B, Dong X, Cheng H, Zheng C, Chen Z, Rodríguez TC, Liang SQ, Xue W, Sontheimer EJ | Nature biotechnology | 35379962 | Nat Biotechnol | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/35379962 |
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice. | Liu P, Liang SQ, Zheng C, Mintzer E, Zhao YG, Ponnienselvan K, Mir A, Sontheimer EJ, Gao G, Flotte TR, Wolfe SA, Xue W | Nature communications | 33837189 | Nat Commun | 2021 Apr 9 | https://www.ncbi.nlm.nih.gov/pubmed/33837189 |
Understanding and repurposing CRISPR-mediated alternative splicing. | Smith JL, Mou H, Xue W | Genome biology | 30400804 | Genome Biol | 2018 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/30400804 |
All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo. | Ibraheim R, Song CQ, Mir A, Amrani N, Xue W, Sontheimer EJ | Genome biology | 30231914 | Genome Biol | 2018 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/30231914 |
Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing. | Li B, Manan RS, Liang SQ, Gordon A, Jiang A, Varley A, Gao G, Langer R, Xue W, Anderson D | Nature biotechnology | 36997680 | Nat Biotechnol | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36997680 |
Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis. | Mou H, Moore J, Malonia SK, Li Y, Ozata DM, Hough S, Song CQ, Smith JL, Fischer A, Weng Z, Green MR, Xue W | Proceedings of the National Academy of Sciences of the United States of America | 28320962 | Proc Natl Acad Sci U S A | 2017 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/28320962 |
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing. | Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson DG | Nature biotechnology | 29131148 | Nat Biotechnol | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29131148 |
Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins. | Lee J, Mou H, Ibraheim R, Liang SQ, Liu P, Xue W, Sontheimer EJ | RNA (New York, N.Y.) | 31439808 | RNA | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31439808 |
Advances in CRISPR/Cas-based Gene Therapy in Human Genetic Diseases. | Wu SS, Li QC, Yin CQ, Xue W, Song CQ | Theranostics | 32292501 | Theranostics | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32292501 |
AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys. | Liang SQ, Navia AW, Ramseier M, Zhou X, Martinez M, Lee C, Zhou C, Wu J, Xie J, Su Q, Wang D, Flotte TR, Anderson DG, Tarantal AF, Shalek AK, Gao G, Xue W | Human gene therapy | 38767512 | Hum Gene Ther | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38767512 |
AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway. | Liang SQ, Walkey CJ, Martinez AE, Su Q, Dickinson ME, Wang D, Lagor WR, Heaney JD, Gao G, Xue W | Molecular therapy : the journal of the American Society of Gene Therapy | 34695545 | Mol Ther | 2022 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/34695545 |
Template-jumping prime editing enables large insertion and exon rewriting in vivo. | Zheng C, Liu B, Dong X, Gaston N, Sontheimer EJ, Xue W | Nature communications | 37291100 | Nat Commun | 2023 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/37291100 |
A salt-sensing kinase in T lymphocytes, SGK1, drives hypertension and hypertensive end-organ damage. | Norlander AE, Saleh MA, Pandey AK, Itani HA, Wu J, Xiao L, Kang J, Dale BL, Goleva SB, Laroumanie F, Du L, Harrison DG, Madhur MS | JCI insight | 28679951 | JCI Insight | 2017 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/28679951 |
LNK deficiency promotes acute aortic dissection and rupture. | Laroumanie F, Korneva A, Bersi MR, Alexander MR, Xiao L, Zhong X, Van Beusecum JP, Chen Y, Saleh MA, McMaster WG, Gavulic KA, Dale BL, Zhao S, Guo Y, Shyr Y, Perrien DS, Cox NJ, Curci JA, Humphrey JD, Madhur MS | JCI insight | 30333305 | JCI Insight | 2018 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/30333305 |
Immune profiling of murine cardiac leukocytes identifies triggering receptor expressed on myeloid cells 2 as a novel mediator of hypertensive heart failure. | Smart CD, Fehrenbach DJ, Wassenaar JW, Agrawal V, Fortune NL, Dixon DD, Cottam MA, Hasty AH, Hemnes AR, Doran AC, Gupta DK, Madhur MS | Cardiovascular research | 37314125 | Cardiovasc Res | 2023 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/37314125 |
Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species. | Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 33015868 | FASEB J | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33015868 |
The immunology of hypertension. | Norlander AE, Madhur MS, Harrison DG | The Journal of experimental medicine | 29247045 | J Exp Med | 2018 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/29247045 |
From Rags to Riches: Moving Beyond RAG1 in Studies of Hypertension. | Madhur MS, Kirabo A, Guzik TJ, Harrison DG | Hypertension (Dallas, Tex. : 1979) | 32078385 | Hypertension | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32078385 |
Inflammation Resolution in the Cardiovascular System: Arterial Hypertension, Atherosclerosis, and Ischemic Heart Disease. | Gonzalez AL, Dungan MM, Smart CD, Madhur MS, Doran AC | Antioxidants & redox signaling | 37125445 | Antioxid Redox Signal | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/37125445 |
Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease. | Wassenaar JW, Smart CD, Fehrenbach DJ, Agrawal V, Dungan MM, Fortune NL, Zhong L, Hemnes AR, Peebles RS Jr, Miller FJ Jr, Doran AC, Madhur MS | JACC. Basic to translational science | 39958476 | JACC Basic Transl Sci | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39958476 |
A Single Nucleotide Polymorphism in SH2B3/LNK Promotes Hypertension Development and Renal Damage. | Alexander MR, Hank S, Dale BL, Himmel L, Zhong X, Smart CD, Fehrenbach DJ, Chen Y, Prabakaran N, Tirado B, Centrella M, Ao M, Du L, Shyr Y, Levy D, Madhur MS | Circulation research | 36169218 | Circ Res | 2022 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/36169218 |
Interleukin 17A: Key Player in the Pathogenesis of Hypertension and a Potential Therapeutic Target. | Davis GK, Fehrenbach DJ, Madhur MS | Current hypertension reports | 33666761 | Curr Hypertens Rep | 2021 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/33666761 |
Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic? | Madhur MS, Elijovich F, Alexander MR, Pitzer A, Ishimwe J, Van Beusecum JP, Patrick DM, Smart CD, Kleyman TR, Kingery J, Peck RN, Laffer CL, Kirabo A | Circulation research | 33793336 | Circ Res | 2021 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/33793336 |
Critical role of Interleukin 21 and T follicular helper cells in hypertension and vascular dysfunction. | Dale BL, Pandey AK, Chen Y, Smart CD, Laroumanie F, Ao M, Xiao L, Dikalova AE, Dikalov SI, Elijovich F, Foss JD, Barbaro NR, Van Beusecum JP, Deger SM, Alsouqi A, Itani HA, Norlander AE, Alexander MR, Zhao S, Ikizler TA, Algood HMS, Madhur MS | JCI insight | 31013256 | JCI Insight | 2019 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/31013256 |
Human monocyte transcriptional profiling identifies IL-18 receptor accessory protein and lactoferrin as novel immune targets in hypertension. | Alexander MR, Norlander AE, Elijovich F, Atreya RV, Gaye A, Gnecco JS, Laffer CL, Galindo CL, Madhur MS | British journal of pharmacology | 29774543 | Br J Pharmacol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29774543 |
Status of Early-Career Academic Cardiology: A Global Perspective. | Tong CW, Madhur MS, Rzeszut AK, Abdalla M, Abudayyeh I, Alexanderson E, Buber J, Feldman DN, Gopinathannair R, Hira RS, Kates AM, Kessler T, Leung S, Raj SR, Spatz ES, Turner MB, Valente AM, West K, Sivaram CA, Hill JA, Mann DL, Freeman AM | Journal of the American College of Cardiology | 29073958 | J Am Coll Cardiol | 2017 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/29073958 |
Evidence for a Causal Role of the SH2B3-β(2)M Axis in Blood Pressure Regulation. | Keefe JA, Hwang SJ, Huan T, Mendelson M, Yao C, Courchesne P, Saleh MA, Madhur MS, Levy D | Hypertension (Dallas, Tex. : 1979) | 30624993 | Hypertension | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30624993 |
Adaptive immune cells in calcific aortic valve disease. | Raddatz MA, Madhur MS, Merryman WD | American journal of physiology. Heart and circulatory physiology | 31050556 | Am J Physiol Heart Circ Physiol | 2019 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/31050556 |
Class switching and high-affinity immunoglobulin G production by B cells is dispensable for the development of hypertension in mice. | Chen Y, Dale BL, Alexander MR, Xiao L, Ao M, Pandey AK, Smart CD, Davis GK, Madhur MS | Cardiovascular research | 32609312 | Cardiovasc Res | 2021 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/32609312 |
Coordinate adaptations of skeletal muscle and kidney to maintain extracellular [K(+)] during K(+)-deficient diet. | McFarlin BE, Chen Y, Priver TS, Ralph DL, Mercado A, Gamba G, Madhur MS, McDonough AA | American journal of physiology. Cell physiology | 32845718 | Am J Physiol Cell Physiol | 2020 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/32845718 |
COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. | Guzik TJ, Mohiddin SA, Dimarco A, Patel V, Savvatis K, Marelli-Berg FM, Madhur MS, Tomaszewski M, Maffia P, D'Acquisto F, Nicklin SA, Marian AJ, Nosalski R, Murray EC, Guzik B, Berry C, Touyz RM, Kreutz R, Wang DW, Bhella D, Sagliocco O, Crea F, Thomson EC, McInnes IB | Cardiovascular research | 32352535 | Cardiovasc Res | 2020 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/32352535 |
Super-Resolution Imaging of Self-Assembled Nanocarriers Using Quantitative Spectroscopic Analysis for Cluster Extraction. | Davis JL, Zhang Y, Yi S, Du F, Song KH, Scott EA, Sun C, Zhang HF | Langmuir : the ACS journal of surfaces and colloids | 32069413 | Langmuir | 2020 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/32069413 |
Acute CD47 Blockade During Ischemic Myocardial Reperfusion Enhances Phagocytosis-Associated Cardiac Repair. | Zhang S, Yeap XY, DeBerge M, Naresh NK, Wang K, Jiang Z, Wilcox JE, White SM, Morrow JP, Burridge PW, Procissi D, Scott EA, Frazier W, Thorp EB | JACC. Basic to translational science | 28920097 | JACC Basic Transl Sci | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28920097 |
Tailoring Nanostructure Morphology for Enhanced Targeting of Dendritic Cells in Atherosclerosis. | Yi S, Allen SD, Liu YG, Ouyang BZ, Li X, Augsornworawat P, Thorp EB, Scott EA | ACS nano | 27935698 | ACS Nano | 2016 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/27935698 |
Leveraging self-assembled nanobiomaterials for improved cancer immunotherapy. | Vincent MP, Navidzadeh JO, Bobbala S, Scott EA | Cancer cell | 35148814 | Cancer Cell | 2022 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/35148814 |
Facile assembly and loading of theranostic polymersomes via multi-impingement flash nanoprecipitation. | Allen S, Osorio O, Liu YG, Scott E | Journal of controlled release : official journal of the Controlled Release Society | 28736263 | J Control Release | 2017 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/28736263 |
Sustained micellar delivery via inducible transitions in nanostructure morphology. | Karabin NB, Allen S, Kwon HK, Bobbala S, Firlar E, Shokuhfar T, Shull KR, Scott EA | Nature communications | 29434200 | Nat Commun | 2018 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/29434200 |
Influences of nanocarrier morphology on therapeutic immunomodulation. | Frey M, Bobbala S, Karabin N, Scott E | Nanomedicine (London, England) | 30084296 | Nanomedicine (Lond) | 2018 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/30084296 |
The Combination of Morphology and Surface Chemistry Defines the Immunological Identity of Nanocarriers in Human Blood. | Vincent MP, Karabin NB, Allen SD, Bobbala S, Frey MA, Yi S, Yang Y, Scott EA | Advanced therapeutics | 34485684 | Adv Ther (Weinh) | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34485684 |
Dendritic peptide-conjugated polymeric nanovectors for non-toxic delivery of plasmid DNA and enhanced non-viral transfection of immune cells. | Yi S, Kim SY, Vincent MP, Yuk SA, Bobbala S, Du F, Scott EA | iScience | 35769884 | iScience | 2022 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/35769884 |
Engineering nanomaterials to address cell-mediated inflammation in atherosclerosis. | Allen S, Liu YG, Scott E | Regenerative engineering and translational medicine | 27135051 | Regen Eng Transl Med | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/27135051 |
Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy. | Vincent MP, Stack T, Vahabikashi A, Li G, Perkumas KM, Ren R, Gong H, Stamer WD, Johnson M, Scott EA | ACS applied materials & interfaces | 34232612 | ACS Appl Mater Interfaces | 2021 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/34232612 |
Just add water: hydratable, morphologically diverse nanocarrier powders for targeted delivery. | Bobbala S, Vincent MP, Scott EA | Nanoscale | 34160529 | Nanoscale | 2021 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/34160529 |
Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability. | Burke JA, Zhang X, Bobbala S, Frey MA, Bohorquez Fuentes C, Freire Haddad H, Allen SD, Richardson RAK, Ameer GA, Scott EA | Nature nanotechnology | 35039683 | Nat Nanotechnol | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35039683 |
On the advancement of polymeric bicontinuous nanospheres toward biomedical applications. | Allen SD, Bobbala S, Karabin NB, Scott EA | Nanoscale horizons | 32254084 | Nanoscale Horiz | 2019 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/32254084 |
Employment of targeted nanoparticles for imaging of cellular processes in cardiovascular disease. | Modak M, Frey MA, Yi S, Liu Y, Scott EA | Current opinion in biotechnology | 32682272 | Curr Opin Biotechnol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32682272 |
Minimizing Molecular Misidentification in Imaging Low-Abundance Protein Interactions Using Spectroscopic Single-Molecule Localization Microscopy. | Zhang Y, Wang G, Huang P, Sun E, Kweon J, Li Q, Zhe J, Ying LL, Zhang HF | Analytical chemistry | 36165784 | Anal Chem | 2022 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/36165784 |
An Injectable Hydrogel Platform for Sustained Delivery of Anti-inflammatory Nanocarriers and Induction of Regulatory T Cells in Atherosclerosis. | Yi S, Karabin NB, Zhu J, Bobbala S, Lyu H, Li S, Liu Y, Frey M, Vincent M, Scott EA | Frontiers in bioengineering and biotechnology | 32582667 | Front Bioeng Biotechnol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32582667 |
Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis. | Allen SD , Liu YG , Kim T , Bobbala S , Yi S , Zhang X , Choi J , Scott EA | Biomaterials science | 30601470 | Biomater Sci | 2019 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/30601470 |
Induction of Mycobacterium Tuberculosis Lipid-Specific T Cell Responses by Pulmonary Delivery of Mycolic Acid-Loaded Polymeric Micellar Nanocarriers. | Shang S, Kats D, Cao L, Morgun E, Velluto D, He Y, Xu Q, Wang CR, Scott EA | Frontiers in immunology | 30538700 | Front Immunol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30538700 |
Employing bicontinuous-to-micellar transitions in nanostructure morphology for on-demand photo-oxidation responsive cytosolic delivery and off-on cytotoxicity. | Bobbala S, Allen SD, Yi S, Vincent M, Frey M, Karabin NB, Scott EA | Nanoscale | 32090217 | Nanoscale | 2020 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/32090217 |
Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation. | Allen S, Vincent M, Scott E | Journal of visualized experiments : JoVE | 30148497 | J Vis Exp | 2018 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/30148497 |
Immunotheranostic Polymersomes Modularly Assembled from Tetrablock and Diblock Copolymers with Oxidation-Responsive Fluorescence. | Du F, Liu YG, Scott EA | Cellular and molecular bioengineering | 28989540 | Cell Mol Bioeng | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28989540 |
Modulation of Schlemm's canal endothelial cell stiffness via latrunculin loaded block copolymer micelles. | Stack T, Vahabikashi A, Johnson M, Scott E | Journal of biomedical materials research. Part A | 29468812 | J Biomed Mater Res A | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29468812 |
Surface engineered polymersomes for enhanced modulation of dendritic cells during cardiovascular immunotherapy. | Yi S, Zhang X, Sangji H, Liu Y, Allen SD, Xiao B, Bobbala S, Braverman CL, Cai L, Hecker PI, DeBerge M, Thorp EB, Temel RE, Stupp SI, Scott EA | Advanced functional materials | 34335131 | Adv Funct Mater | 2019 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/34335131 |
Homopolymer self-assembly of poly(propylene sulfone) hydrogels via dynamic noncovalent sulfone-sulfone bonding. | Du F, Qiao B, Nguyen TD, Vincent MP, Bobbala S, Yi S, Lescott C, Dravid VP, Olvera de la Cruz M, Scott EA | Nature communications | 32994414 | Nat Commun | 2020 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/32994414 |
Targeted Delivery of Cell Softening Micelles to Schlemm's Canal Endothelial Cells for Treatment of Glaucoma. | Stack T, Vincent M, Vahabikashi A, Li G, Perkumas KM, Stamer WD, Johnson M, Scott E | Small (Weinheim an der Bergstrasse, Germany) | 33015961 | Small | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33015961 |
Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets. | Vincent MP, Bobbala S, Karabin NB, Frey M, Liu Y, Navidzadeh JO, Stack T, Scott EA | Nature communications | 33510170 | Nat Commun | 2021 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/33510170 |
Enhancing subcutaneous injection and target tissue accumulation of nanoparticles via co-administration with macropinocytosis inhibitory nanoparticles (MiNP). | Stack T, Liu Y, Frey M, Bobbala S, Vincent M, Scott E | Nanoscale horizons | 33884386 | Nanoscale Horiz | 2021 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/33884386 |
Sequential intracellular release of water-soluble cargos from Shell-crosslinked polymersomes. | Du F, Bobbala S, Yi S, Scott EA | Journal of controlled release : official journal of the Controlled Release Society | 29601932 | J Control Release | 2018 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/29601932 |
Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection. | Li X, Yi S, Scariot DB, Martinez SJ, Falk BA, Olson CL, Romano PS, Scott EA, Engman DM | JCI insight | 33986194 | JCI Insight | 2021 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/33986194 |
Flash nanoprecipitation permits versatile assembly and loading of polymeric bicontinuous cubic nanospheres. | Bobbala S , Allen SD , Scott EA | Nanoscale | 29255814 | Nanoscale | 2018 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/29255814 |
Pi-stacking Enhances Stability, Scalability of Formation, Control over Flexibility and Circulation Time of Polymeric Filaments. | Li S, Bobbala S, Vincent MP, Modak M, Liu Y, Scott EA | Advanced nanobiomed research | 34870281 | Adv Nanobiomed Res | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34870281 |
Microstructural Infarct Border Zone Remodeling in the Post-infarct Swine Heart Measured by Diffusion Tensor MRI. | Kung GL, Vaseghi M, Gahm JK, Shevtsov J, Garfinkel A, Shivkumar K, Ennis DB | Frontiers in physiology | 30246802 | Front Physiol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30246802 |
Editorial Commentary: Chronic obstructive pulmonary disease and sudden cardiac death: Cause and effect or simply an association? | Hoffman J, Vaseghi M | Trends in cardiovascular medicine | 27238054 | Trends Cardiovasc Med | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27238054 |
Cardiac sympathetic denervation for intractable ventricular arrhythmias in Chagas disease. | Saenz LC, Corrales FM, Bautista W, Traina M, Meymandi S, Rodriguez DA, Tellez LJ, Vaseghi M, Garcia F, Shivkumar K, Bradfield JS | Heart rhythm | 26969783 | Heart Rhythm | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26969783 |
Cardiac Sympathetic Denervation for Refractory Ventricular Arrhythmias. | Vaseghi M, Barwad P, Malavassi Corrales FJ, Tandri H, Mathuria N, Shah R, Sorg JM, Gima J, Mandal K, Sàenz Morales LC, Lokhandwala Y, Shivkumar K | Journal of the American College of Cardiology | 28641796 | J Am Coll Cardiol | 2017 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/28641796 |
Cardiac sympathetic innervation via middle cervical and stellate ganglia and antiarrhythmic mechanism of bilateral stellectomy. | Irie T, Yamakawa K, Hamon D, Nakamura K, Shivkumar K, Vaseghi M | American journal of physiology. Heart and circulatory physiology | 28011590 | Am J Physiol Heart Circ Physiol | 2017 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/28011590 |
Outcomes of Catheter Ablation of Ventricular Tachycardia Based on Etiology in Nonischemic Heart Disease: An International Ventricular Tachycardia Ablation Center Collaborative Study. | Vaseghi M, Hu TY, Tung R, Vergara P, Frankel DS, Di Biase L, Tedrow UB, Gornbein JA, Yu R, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Burkhardt JD, Tholakanahalli VN, Dickfeld TM, Weiss JP, Bunch TJ, Reddy M, Callans DJ, Lakkireddy DR, Natale A, Marchlinski FE, Stevenson WG, Della Bella P, Shivkumar K | JACC. Clinical electrophysiology | 30236386 | JACC Clin Electrophysiol | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30236386 |
Sex and Race/Ethnicity Differences in Atrial Fibrillation. | Volgman AS, Bairey Merz CN, Benjamin EJ, Curtis AB, Fang MC, Lindley KJ, Pepine CJ, Vaseghi M, Waldo AL, Wenger NK, Russo AM | Journal of the American College of Cardiology | 31779796 | J Am Coll Cardiol | 2019 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/31779796 |
The autonomic nervous system and ventricular arrhythmias in myocardial infarction and heart failure. | Wu P, Vaseghi M | Pacing and clinical electrophysiology : PACE | 31823401 | Pacing Clin Electrophysiol | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31823401 |
European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on risk assessment in cardiac arrhythmias: use the right tool for the right outcome, in the right population. | Nielsen JC, Lin YJ, de Oliveira Figueiredo MJ, Sepehri Shamloo A, Alfie A, Boveda S, Dagres N, Di Toro D, Eckhardt LL, Ellenbogen K, Hardy C, Ikeda T, Jaswal A, Kaufman E, Krahn A, Kusano K, Kutyifa V, Lim HS, Lip GYH, Nava-Townsend S, Pak HN, Rodríguez Diez G, Sauer W, Saxena A, Svendsen JH, Vanegas D, Vaseghi M, Wilde A, Bunch TJ, ESC Scientific Document Group, Buxton AE, Calvimontes G, Chao TF, Eckardt L, Estner H, Gillis AM, Isa R, Kautzner J, Maury P, Moss JD, Nam GB, Olshansky B, Pava Molano LF, Pimentel M, Prabhu M, Tzou WS, Sommer P, Swampillai J, Vidal A, Deneke T, Hindricks G, Leclercq C | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology | 32538434 | Europace | 2020 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/32538434 |
Update on prevention and treatment of sudden cardiac arrest. | Krokhaleva Y, Vaseghi M | Trends in cardiovascular medicine | 30449537 | Trends Cardiovasc Med | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30449537 |
Risk Stratification and Sudden Cardiac Death: Is It Time to Include Autonomic Variables? | Khakpour H, Vaseghi M | Circulation. Cardiovascular imaging | 28794140 | Circ Cardiovasc Imaging | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28794140 |
Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics. | Shivkumar K, Ajijola OA, Anand I, Armour JA, Chen PS, Esler M, De Ferrari GM, Fishbein MC, Goldberger JJ, Harper RM, Joyner MJ, Khalsa SS, Kumar R, Lane R, Mahajan A, Po S, Schwartz PJ, Somers VK, Valderrabano M, Vaseghi M, Zipes DP | The Journal of physiology | 27114333 | J Physiol | 2016 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/27114333 |
Parasympathetic dysfunction and antiarrhythmic effect of vagal nerve stimulation following myocardial infarction. | Vaseghi M, Salavatian S, Rajendran PS, Yagishita D, Woodward WR, Hamon D, Yamakawa K, Irie T, Habecker BA, Shivkumar K | JCI insight | 28814663 | JCI Insight | 2017 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/28814663 |
Thoracic Epidural Anesthesia Can Be Effective for the Short-Term Management of Ventricular Tachycardia Storm. | Do DH, Bradfield J, Ajijola OA, Vaseghi M, Le J, Rahman S, Mahajan A, Nogami A, Boyle NG, Shivkumar K | Journal of the American Heart Association | 29079570 | J Am Heart Assoc | 2017 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/29079570 |
Antiarrhythmic effects of vagal nerve stimulation after cardiac sympathetic denervation in the setting of chronic myocardial infarction. | Yamaguchi N, Yamakawa K, Rajendran PS, Takamiya T, Vaseghi M | Heart rhythm | 29530832 | Heart Rhythm | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29530832 |
Premature ventricular contractions activate vagal afferents and alter autonomic tone: implications for premature ventricular contraction-induced cardiomyopathy. | Salavatian S, Yamaguchi N, Hoang J, Lin N, Patel S, Ardell JL, Armour JA, Vaseghi M | American journal of physiology. Heart and circulatory physiology | 31322427 | Am J Physiol Heart Circ Physiol | 2019 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/31322427 |
Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y. | Hoang JD, Salavatian S, Yamaguchi N, Swid MA, David H, Vaseghi M | JCI insight | 32493842 | JCI Insight | 2020 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/32493842 |
Arrhythmic Risk Profile and Outcomes of Patients Undergoing Cardiac Sympathetic Denervation for Recurrent Monomorphic Ventricular Tachycardia After Ablation. | Dusi V, Gornbein J, Do DH, Sorg JM, Khakpour H, Krokhaleva Y, Ajijola OA, Macias C, Bradfield JS, Buch E, Fujimura OA, Boyle NG, Yanagawa J, Lee JM, Shivkumar K, Vaseghi M | Journal of the American Heart Association | 33441022 | J Am Heart Assoc | 2021 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/33441022 |
A novel mechanism for regulation of cardiac Ca(2+) current by estradiol: cAMP-ing out at the basal epicardium. | Hoang JD, Vaseghi M | Heart rhythm | 29382545 | Heart Rhythm | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29382545 |
Cardiac neuroanatomy - Imaging nerves to define functional control. | Hanna P, Rajendran PS, Ajijola OA, Vaseghi M, Andrew Armour J, Ardell JL, Shivkumar K | Autonomic neuroscience : basic & clinical | 28802636 | Auton Neurosci | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28802636 |
Cardiac Innervation and the Autonomic Nervous System in Sudden Cardiac Death. | Huang WA, Boyle NG, Vaseghi M | Cardiac electrophysiology clinics | 29173409 | Card Electrophysiol Clin | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29173409 |
No sympathy for the hypoxic: the role of fetal oxygenation in autonomic dysfunction. | Hoang JD, Vaseghi M | The Journal of physiology | 29774552 | J Physiol | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29774552 |
Liver Disease as a Predictor of New-Onset Atrial Fibrillation. | Huang WA, Dunipace EA, Sorg JM, Vaseghi M | Journal of the American Heart Association | 30371253 | J Am Heart Assoc | 2018 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/30371253 |
Ventricular Tachycardia in Dilated Cardiomyopathy: Is it Time for Genetic Testing in All Patients? | Nguyen HL, Vaseghi M | JACC. Clinical electrophysiology | 32972545 | JACC Clin Electrophysiol | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32972545 |
Relationship between sinus rhythm late activation zones and critical sites for scar-related ventricular tachycardia: systematic analysis of isochronal late activation mapping. | Irie T, Yu R, Bradfield JS, Vaseghi M, Buch EF, Ajijola O, Macias C, Fujimura O, Mandapati R, Boyle NG, Shivkumar K, Tung R | Circulation. Arrhythmia and electrophysiology | 25740836 | Circ Arrhythm Electrophysiol | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25740836 |
Arrhythmogenic Right Ventricular Cardiomyopathy: Electroarchitecture of the Substrate. | Watanabe A, Seki A, Fishbein MC, Shivkumar K, Vaseghi M | HeartRhythm case reports | 26955520 | HeartRhythm Case Rep | 2016 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/26955520 |
Recurrent ventricular tachycardia after cardiac sympathetic denervation: Prolonged cycle length with improved hemodynamic tolerance and ablation outcomes. | Hayase J, Dusi V, Do D, Ajijola OA, Vaseghi M, Lee JM, Yanagawa J, Hoftman N, Revels S, Buch EF, Khakpour H, Fujimura O, Krokhaleva Y, Macias C, Sorg J, Gima J, Pavez G, Boyle NG, Shivkumar K, Bradfield JS | Journal of cardiovascular electrophysiology | 32558054 | J Cardiovasc Electrophysiol | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32558054 |
Looking Beyond Storm: Forecast Remains Gloomy for Clustered Ventricular Arrhythmias. | Khakpour H, Vaseghi M | JACC. Clinical electrophysiology | 32192685 | JACC Clin Electrophysiol | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32192685 |
Myocardial infarction reduces cardiac nociceptive neurotransmission through the vagal ganglia. | Salavatian S, Hoang JD, Yamaguchi N, Lokhandwala ZA, Swid MA, Armour JA, Ardell JL, Vaseghi M | JCI insight | 35015733 | JCI Insight | 2022 Feb 22 | https://www.ncbi.nlm.nih.gov/pubmed/35015733 |
Phase-noise analysis of swept-source optical coherence tomography systems. | Ling Y, Gan Y, Yao X, Hendon CP | Optics letters | 28362762 | Opt Lett | 2017 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/28362762 |
Comparative study of texture features in OCT images at different scales for human breast tissue classification. | Yu Gan, Xinwen Yao, Chang E, Bin Amir S, Hibshoosh H, Feldman S, Hendon CP | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 28269144 | Annu Int Conf IEEE Eng Med Biol Soc | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28269144 |
An automated 3D registration method for optical coherence tomography volumes. | Gan Y, Yao W, Myers KM, Hendon CP | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 25570837 | Annu Int Conf IEEE Eng Med Biol Soc | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25570837 |
Analyzing three-dimensional ultrastructure of human cervical tissue using optical coherence tomography. | Gan Y, Yao W, Myers KM, Vink JY, Wapner RJ, Hendon CP | Biomedical optics express | 25908997 | Biomed Opt Express | 2015 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/25908997 |
Near-infrared spectroscopy integrated catheter for characterization of myocardial tissues: preliminary demonstrations to radiofrequency ablation therapy for atrial fibrillation. | Singh-Moon RP, Marboe CC, Hendon CP | Biomedical optics express | 26203376 | Biomed Opt Express | 2015 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/26203376 |
Compressed sensing of human breast optical coherence 3-D image volume data using predictive coding. | Song Cho DM, Jerome MJ, Hendon CP | Biomedical optics express | 38021138 | Biomed Opt Express | 2023 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/38021138 |
Visualization and tissue classification of human breast cancer images using ultrahigh-resolution OCT. | Yao X, Gan Y, Chang E, Hibshoosh H, Feldman S, Hendon C | Lasers in surgery and medicine | 28264146 | Lasers Surg Med | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28264146 |
Multicontrast endomyocardial imaging by single-channel high-resolution cross-polarization optical coherence tomography. | Yao X, Gan Y, Ling Y, Marboe CC, Hendon CP | Journal of biophotonics | 29165902 | J Biophotonics | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29165902 |
Millimeter-scale chip-based supercontinuum generation for optical coherence tomography. | Ji X, Mojahed D, Okawachi Y, Gaeta AL, Hendon CP, Lipson M | Science advances | 34533990 | Sci Adv | 2021 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/34533990 |
Optical coherence tomography-enabled classification of the human venoatrial junction. | Joasil AS, Therien AM, Hendon CP | Journal of biomedical optics | 39840147 | J Biomed Opt | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39840147 |
Myocardial imaging using ultrahigh-resolution spectral domain optical coherence tomography. | Yao X, Gan Y, Marboe CC, Hendon CP | Journal of biomedical optics | 27001162 | J Biomed Opt | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27001162 |
Frequency-constrained robust principal component analysis: a sparse representation approach to segmentation of dynamic features in optical coherence tomography imaging. | McLean JP, Ling Y, Hendon CP | Optics express | 29041245 | Opt Express | 2017 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/29041245 |
Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector. | Ling Y, Yao X, Hendon CP | Biomedical optics express | 29082103 | Biomed Opt Express | 2017 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/29082103 |
Feasibility of near-infrared spectroscopy as a tool for anatomical mapping of the human epicardium. | Singh-Moon RP, Park SY, Song Cho DM, Vaidya A, Marboe CC, Wan EY, Hendon CP | Biomedical optics express | 32923031 | Biomed Opt Express | 2020 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/32923031 |
Chip-based frequency comb sources for optical coherence tomography. | Ji X, Yao X, Klenner A, Gan Y, Gaeta AL, Hendon CP, Lipson M | Optics express | 31503744 | Opt Express | 2019 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/31503744 |
Monitoring of irrigated lesion formation with single fiber based multispectral system using machine learning. | Park SY, Singh-Moon RP, Yang H, Hendon CP | Journal of biophotonics | 35666015 | J Biophotonics | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/35666015 |
Heterogeneity Measurement of Cardiac Tissues Leveraging Uncertainty Information from Image Segmentation. | Huang Z, Gan Y, Lye T, Zhang H, Laine A, Angelini ED, Hendon C | Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention | 34169298 | Med Image Comput Comput Assist Interv | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/34169298 |
A continuous fiber distribution material model for human cervical tissue. | Myers KM, Hendon CP, Gan Y, Yao W, Yoshida K, Fernandez M, Vink J, Wapner RJ | Journal of biomechanics | 25817474 | J Biomech | 2015 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/25817474 |
Real-time optical spectroscopic monitoring of nonirrigated lesion progression within atrial and ventricular tissues. | Singh-Moon RP, Yao X, Iyer V, Marboe C, Whang W, Hendon CP | Journal of biophotonics | 30058239 | J Biophotonics | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30058239 |
3-D compressed sensing optical coherence tomography using predictive coding. | McLean JP, Hendon CP | Biomedical optics express | 33996246 | Biomed Opt Express | 2021 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/33996246 |
Three-dimensional collagen fiber mapping and tractography of human uterine tissue using OCT. | McLean JP, Fang S, Gallos G, Myers KM, Hendon CP | Biomedical optics express | 33149968 | Biomed Opt Express | 2020 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/33149968 |
Ex vivo visualization of human ciliated epithelium and quantitative analysis of induced flow dynamics by using optical coherence tomography. | Ling Y, Yao X, Gamm UA, Arteaga-Solis E, Emala CW, Choma MA, Hendon CP | Lasers in surgery and medicine | 28231402 | Lasers Surg Med | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28231402 |
Tissue-Specific Optical Mapping Models of Swine Atria Informed by Optical Coherence Tomography. | Lye TH, Vincent KP, McCulloch AD, Hendon CP | Biophysical journal | 29590604 | Biophys J | 2018 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/29590604 |
Compressed sensing-enabled phase-sensitive swept-source optical coherence tomography. | Ling Y, Meiniel W, Singh-Moon R, Angelini E, Olivo-Marin JC, Hendon CP | Optics express | 30696165 | Opt Express | 2019 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/30696165 |
Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women. | Yao W, Gan Y, Myers KM, Vink JY, Wapner RJ, Hendon CP | PloS one | 27898677 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27898677 |
Automated classification of optical coherence tomography images of human atrial tissue. | Gan Y, Tsay D, Amir SB, Marboe CC, Hendon CP | Journal of biomedical optics | 26926869 | J Biomed Opt | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26926869 |
Mapping the human pulmonary venoatrial junction with optical coherence tomography. | Lye TH, Iyer V, Marboe CC, Hendon CP | Biomedical optics express | 30800491 | Biomed Opt Express | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30800491 |
Fully Automated Postlumpectomy Breast Margin Assessment Utilizing Convolutional Neural Network Based Optical Coherence Tomography Image Classification Method. | Mojahed D, Ha RS, Chang P, Gan Y, Yao X, Angelini B, Hibshoosh H, Taback B, Hendon CP | Academic radiology | 31324579 | Acad Radiol | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/31324579 |
Characterization of the human myocardium by optical coherence tomography. | Gan Y, Lye TH, Marboe CC, Hendon CP | Journal of biophotonics | 31400074 | J Biophotonics | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31400074 |
Imaging of subendocardial adipose tissue and fiber orientation distributions in the human left atrium using optical coherence tomography. | Lye TH, Marboe CC, Hendon CP | Journal of cardiovascular electrophysiology | 31661178 | J Cardiovasc Electrophysiol | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31661178 |
Optical coherence tomography imaging of cardiac substrates. | Hendon CP, Lye TH, Yao X, Gan Y, Marboe CC | Quantitative imaging in medicine and surgery | 31281782 | Quant Imaging Med Surg | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/31281782 |
Optical coherence tomography holds promise to transform the diagnostic anatomic pathology gross evaluation process. | Mojahed D, Applegate M, Guo H, Taback B, Ha R, Hibshoosh H, Hendon C | Journal of biomedical optics | 36050827 | J Biomed Opt | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36050827 |
Cardiac endocardial left atrial substrate and lesion depth mapping using near-infrared spectroscopy. | Park SY, Yang H, Marboe C, Ziv O, Laurita K, Rollins A, Saluja D, Hendon CP | Biomedical optics express | 35519253 | Biomed Opt Express | 2022 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/35519253 |
Quantification of irrigated lesion morphology using near-infrared spectroscopy. | Park SY, Singh-Moon R, Yang H, Saluja D, Hendon C | Scientific reports | 34635764 | Sci Rep | 2021 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/34635764 |
Cardiac Adipose Tissue Segmentation via Image-Level Annotations. | Huang Z, Gan Y, Lye T, Liu Y, Zhang H, Laine A, Angelini E, Hendon C | IEEE journal of biomedical and health informatics | 37023157 | IEEE J Biomed Health Inform | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37023157 |
Cardiac Light-Sheet Fluorescent Microscopy for Multi-Scale and Rapid Imaging of Architecture and Function. | Fei P, Lee J, Packard RR, Sereti KI, Xu H, Ma J, Ding Y, Kang H, Chen H, Sung K, Kulkarni R, Ardehali R, Kuo CC, Xu X, Ho CM, Hsiai TK | Scientific reports | 26935567 | Sci Rep | 2016 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/26935567 |
Harnessing the versatility of PLGA nanoparticles for targeted Cre-mediated recombination. | Nguyen NB, Chen CH, Zhang Y, Zhao P, Wu BM, Ardehali R | Nanomedicine : nanotechnology, biology, and medicine | 31026512 | Nanomedicine | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31026512 |
Translational aspects of cardiac cell therapy. | Chen CH, Sereti KI, Wu BM, Ardehali R | Journal of cellular and molecular medicine | 26119413 | J Cell Mol Med | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26119413 |
Sendai virus based direct cardiac reprogramming: what lies ahead? | Engel JL, Ardehali R | Stem cell investigation | 30498748 | Stem Cell Investig | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30498748 |
Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. | Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, Mikkola HKA, Iruela-Arispe ML, Ardehali R | Nature communications | 29467410 | Nat Commun | 2018 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/29467410 |
In Vivo Clonal Analysis of Cardiomyocytes. | Nguyen NB, Fernandez GE, Ding Y, Hsiai T, Ardehali R | Methods in molecular biology (Clifton, N.J.) | 32857378 | Methods Mol Biol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/32857378 |
Direct Cardiac Reprogramming: Progress and Promise. | Engel JL, Ardehali R | Stem cells international | 29731772 | Stem Cells Int | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29731772 |
Cardiac fibrosis: potential therapeutic targets. | Park S, Nguyen NB, Pezhouman A, Ardehali R | Translational research : the journal of laboratory and clinical medicine | 30930180 | Transl Res | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30930180 |
Direct cardiac reprogramming: A new frontier in heart regeneration. | Ardehali R | Seminars in cell & developmental biology | 34538519 | Semin Cell Dev Biol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34538519 |
Environmental factors influence somatic cell reprogramming to cardiomyocyte-like cells. | Van Handel B, Wang L, Ardehali R | Seminars in cell & developmental biology | 34083115 | Semin Cell Dev Biol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34083115 |
Cardiac Fibrosis Is Associated With Decreased Circulating Levels of Full-Length CILP in Heart Failure. | Park S, Ranjbarvaziri S, Zhao P, Ardehali R | JACC. Basic to translational science | 32478206 | JACC Basic Transl Sci | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32478206 |
Heart Regeneration by Endogenous Stem Cells and Cardiomyocyte Proliferation: Controversy, Fallacy, and Progress. | He L, Nguyen NB, Ardehali R, Zhou B | Circulation | 32687441 | Circulation | 2020 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/32687441 |
Biomarkers of Human Pluripotent Stem Cell-Derived Cardiac Lineages. | Skelton RJP, Kamp TJ, Elliott DA, Ardehali R | Trends in molecular medicine | 28576602 | Trends Mol Med | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28576602 |
Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. | Park S, Ranjbarvaziri S, Lay FD, Zhao P, Miller MJ, Dhaliwal JS, Huertas-Vazquez A, Wu X, Qiao R, Soffer JM, Rau C, Wang Y, Mikkola HKA, Lusis AJ, Ardehali R | Circulation | 29950403 | Circulation | 2018 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/29950403 |
Generation of Nkx2-5/CreER transgenic mice for inducible Cre expression in developing hearts. | Ranjbarvaziri S, Park S, Nguyen NB, Gilmore WB, Zhao P, Ardehali R | Genesis (New York, N.Y. : 2000) | 28589709 | Genesis | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28589709 |
Arrhythmia in stem cell transplantation. | Almeida SO, Skelton RJ, Adigopula S, Ardehali R | Cardiac electrophysiology clinics | 26002399 | Card Electrophysiol Clin | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26002399 |
HBL1 Is a Human Long Noncoding RNA that Modulates Cardiomyocyte Development from Pluripotent Stem Cells by Counteracting MIR1. | Liu J, Li Y, Lin B, Sheng Y, Yang L | Developmental cell | 28829943 | Dev Cell | 2017 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/28829943 |
HBL1 Is a Human Long Noncoding RNA that Modulates Cardiomyocyte Development from Pluripotent Stem Cells by Counteracting MIR1. | Liu J, Li Y, Lin B, Sheng Y, Yang L | Developmental cell | 29112854 | Dev Cell | 2017 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/29112854 |
Mechanism of automaticity in cardiomyocytes derived from human induced pluripotent stem cells. | Kim JJ, Yang L, Lin B, Zhu X, Sun B, Kaplan AD, Bett GC, Rasmusson RL, London B, Salama G | Journal of molecular and cellular cardiology | 25644533 | J Mol Cell Cardiol | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25644533 |
Genome-wide studies reveal the essential and opposite roles of ARID1A in controlling human cardiogenesis and neurogenesis from pluripotent stem cells. | Liu J, Liu S, Gao H, Han L, Chu X, Sheng Y, Shou W, Wang Y, Liu Y, Wan J, Yang L | Genome biology | 32646524 | Genome Biol | 2020 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/32646524 |
Comparative transcriptomic analysis of multiple cardiovascular fates from embryonic stem cells predicts novel regulators in human cardiogenesis. | Li Y, Lin B, Yang L | Scientific reports | 25997157 | Sci Rep | 2015 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/25997157 |
Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy. | Lin B, Li Y, Han L, Kaplan AD, Ao Y, Kalra S, Bett GC, Rasmusson RL, Denning C, Yang L | Disease models & mechanisms | 25791035 | Dis Model Mech | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25791035 |
Multiscale reverse engineering of the human ocular surface. | Seo J, Byun WY, Alisafaei F, Georgescu A, Yi YS, Massaro-Giordano M, Shenoy VB, Lee V, Bunya VY, Huh D | Nature medicine | 31384041 | Nat Med | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31384041 |
Microphysiological Engineering of Self-Assembled and Perfusable Microvascular Beds for the Production of Vascularized Three-Dimensional Human Microtissues. | Paek J, Park SE, Lu Q, Park KT, Cho M, Oh JM, Kwon KW, Yi YS, Song JW, Edelstein HI, Ishibashi J, Yang W, Myerson JW, Kiseleva RY, Aprelev P, Hood ED, Stambolian D, Seale P, Muzykantov VR, Huh D | ACS nano | 31194909 | ACS Nano | 2019 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/31194909 |
Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue. | Mondrinos MJ, Alisafaei F, Yi AY, Ahmadzadeh H, Lee I, Blundell C, Seo J, Osborn M, Jeon TJ, Kim SM, Shenoy VB, Huh D | Science advances | 33712463 | Sci Adv | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33712463 |
In Vitro Granuloma Models of Tuberculosis: Potential and Challenges. | Elkington P, Lerm M, Kapoor N, Mahon R, Pienaar E, Huh D, Kaushal D, Schlesinger LS | The Journal of infectious diseases | 30929010 | J Infect Dis | 2019 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/30929010 |
Placenta-on-a-chip: a novel platform to study the biology of the human placenta. | Lee JS, Romero R, Han YM, Kim HC, Kim CJ, Hong JS, Huh D | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians | 26075842 | J Matern Fetal Neonatal Med | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26075842 |
A microphysiological model of the human placental barrier. | Blundell C, Tess ER, Schanzer AS, Coutifaris C, Su EJ, Parry S, Huh D | Lab on a chip | 27229450 | Lab Chip | 2016 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/27229450 |
Soft robotic constrictor for in vitro modeling of dynamic tissue compression. | Paek J, Song JW, Ban E, Morimitsu Y, Osuji CO, Shenoy VB, Huh DD | Scientific reports | 34389738 | Sci Rep | 2021 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/34389738 |
Polydopamine-Based Interfacial Engineering of Extracellular Matrix Hydrogels for the Construction and Long-Term Maintenance of Living Three-Dimensional Tissues. | Park SE, Georgescu A, Oh JM, Kwon KW, Huh D | ACS applied materials & interfaces | 31199616 | ACS Appl Mater Interfaces | 2019 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/31199616 |
Self-organization of the hematopoietic vascular niche and emergent innate immunity on a chip. | Georgescu A, Oved JH, Galarraga JH, Cantrell T, Mehta S, Dulmovits BM, Olson TS, Fattahi P, Wang A, Candarlioglu PL, Muvaffak A, Kim MM, Aydin SA, Seo J, Diffenderfer ES, Lynch A, Worthen GS, Huh DD | Cell stem cell | 39642865 | Cell Stem Cell | 2024 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/39642865 |
Native extracellular matrix-derived semipermeable, optically transparent, and inexpensive membrane inserts for microfluidic cell culture. | Mondrinos MJ, Yi YS, Wu NK, Ding X, Huh D | Lab on a chip | 28809418 | Lab Chip | 2017 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/28809418 |
A Human Vascular Injury-on-a-Chip Model of Hemostasis. | Poventud-Fuentes I, Kwon KW, Seo J, Tomaiuolo M, Stalker TJ, Brass LF, Huh D | Small (Weinheim an der Bergstrasse, Germany) | 33150735 | Small | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33150735 |
Organoids-on-a-chip. | Park SE, Georgescu A, Huh D | Science (New York, N.Y.) | 31171693 | Science | 2019 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/31171693 |
A bioinspired microfluidic model of liquid plug-induced mechanical airway injury. | Song JW, Paek J, Park KT, Seo J, Huh D | Biomicrofluidics | 29887935 | Biomicrofluidics | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29887935 |
Placental Drug Transport-on-a-Chip: A Microengineered In Vitro Model of Transporter-Mediated Drug Efflux in the Human Placental Barrier. | Blundell C, Yi YS, Ma L, Tess ER, Farrell MJ, Georgescu A, Aleksunes LM, Huh D | Advanced healthcare materials | 29121458 | Adv Healthc Mater | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29121458 |
A microengineered pathophysiological model of early-stage breast cancer. | Choi Y, Hyun E, Seo J, Blundell C, Kim HC, Lee E, Lee SH, Moon A, Moon WK, Huh D | Lab on a chip | 26158500 | Lab Chip | 2015 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/26158500 |
Geometric engineering of organoid culture for enhanced organogenesis in a dish. | Park SE, Kang S, Paek J, Georgescu A, Chang J, Yi AY, Wilkins BJ, Karakasheva TA, Hamilton KE, Huh DD | Nature methods | 36280722 | Nat Methods | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/36280722 |
Bacterial Pneumonia in Patients with Cancer: Novel Risk Factors and Management. | Wong JL, Evans SE | Clinics in chest medicine | 28477638 | Clin Chest Med | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28477638 |
Progression of the Radiologic Severity Index predicts mortality in patients with parainfluenza virus-associated lower respiratory infections. | Sheshadri A, Shah DP, Godoy M, Erasmus JJ, Song J, Li L, Evans SE, Chemaly RF, Dickey BF, Ost DE | PloS one | 29771962 | PLoS One | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29771962 |
Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense. | Leiva-Juárez MM, Kolls JK, Evans SE | Mucosal immunology | 28812547 | Mucosal Immunol | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28812547 |
Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir. | Leiva-Juarez MM, Kirkpatrick CT, Gilbert BE, Scott B, Tuvim MJ, Dickey BF, Evans SE, Markesich D | European journal of pharmacology | 29066417 | Eur J Pharmacol | 2018 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/29066417 |
Editorial: Purinergic Signaling and Inflammation. | Yuan X, Ferrari D, Mills T, Wang Y, Czopik A, Doursout MF, Evans SE, Idzko M, Eltzschig HK | Frontiers in immunology | 34093597 | Front Immunol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34093597 |
OBIF: an omics-based interaction framework to reveal molecular drivers of synergy. | Pantaleón García J, Kulkarni VV, Reese TC, Wali S, Wase SJ, Zhang J, Singh R, Caetano MS, Kadara H, Moghaddam SJ, Johnson FM, Wang J, Wang Y, Evans SE | NAR genomics and bioinformatics | 35387383 | NAR Genom Bioinform | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35387383 |
Muc5b is required for airway defence. | Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM | Nature | 24317696 | Nature | 2014 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/24317696 |
The development and plasticity of alveolar type 1 cells. | Yang J, Hernandez BJ, Martinez Alanis D, Narvaez del Pilar O, Vila-Ellis L, Akiyama H, Evans SE, Ostrin EJ, Chen J | Development (Cambridge, England) | 26586225 | Development | 2016 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/26586225 |
Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice. | Goldblatt DL, Flores JR, Valverde Ha G, Jaramillo AM, Tkachman S, Kirkpatrick CT, Wali S, Hernandez B, Ost DE, Scott BL, Chen J, Evans SE, Tuvim MJ, Dickey BF | British journal of pharmacology | 31968123 | Br J Pharmacol | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/31968123 |
Targeting the Hypoxia-Adenosine Link for Controlling Excessive Inflammation. | Czopik A, Yuan X, Evans SE, Eltzschig HK | Anesthesiology | 34046661 | Anesthesiology | 2021 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/34046661 |
Selective Modulation of the Pulmonary Innate Immune Response Does Not Change Lung Microbiota in Healthy Mice. | Pantaleón García J, Hinkle KJ, Falkowski NR, Evans SE, Dickson RP | American journal of respiratory and critical care medicine | 34153197 | Am J Respir Crit Care Med | 2021 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/34153197 |
Pneumonia in the neutropenic cancer patient. | Evans SE, Ost DE | Current opinion in pulmonary medicine | 25784246 | Curr Opin Pulm Med | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25784246 |
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis. | Abe JI, Ko KA, Kotla S, Wang Y, Paez-Mayorga J, Shin IJ, Imanishi M, Vu HT, Tao Y, Leiva-Juarez MM, Thomas TN, Medina JL, Won JH, Fujii Y, Giancursio CJ, McBeath E, Shin JH, Guzman L, Abe RJ, Taunton J, Mochizuki N, Faubion W, Cooke JP, Fujiwara K, Evans SE, Le NT | JCI insight | 30944250 | JCI Insight | 2019 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/30944250 |
Future Research Directions in Pneumonia. NHLBI Working Group Report. | Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, Orihuela CJ, Peyrani P, Prince AS, Ramírez JA, Ridge KM, Sethi S, Suratt BT, Sznajder JI, Tsalik EL, Walkey AJ, Yende S, Aggarwal NR, Caler EV, Mizgerd JP | American journal of respiratory and critical care medicine | 29546996 | Am J Respir Crit Care Med | 2018 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/29546996 |
Minimizing caging effects in murine lung microbiome studies. | Pantaleón García J, Dickson RP, Evans SE | American journal of physiology. Lung cellular and molecular physiology | 35944140 | Am J Physiol Lung Cell Mol Physiol | 2022 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/35944140 |
Epithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice. | Goldblatt DL, Valverde Ha G, Wali S, Kulkarni VV, Longmire MK, Jaramillo AM, Chittuluru RP, Fouts A, Martinez-Moczygemba M, Lei JT, Huston DP, Tuvim MJ, Dickey BF, Evans SE | Frontiers in pharmacology | 36105216 | Front Pharmacol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36105216 |
Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial immunometabolic modulation. | Wang Y, Kulkarni VV, Pantaleón García J, Leiva-Juárez MM, Goldblatt DL, Gulraiz F, Vila Ellis L, Chen J, Longmire MK, Donepudi SR, Lorenzi PL, Wang H, Wong LJ, Tuvim MJ, Evans SE | PLoS pathogens | 37695784 | PLoS Pathog | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37695784 |
Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands. | Alfaro VY, Goldblatt DL, Valverde GR, Munsell MF, Quinton LJ, Walker AK, Dantzer R, Varadhachary A, Scott BL, Evans SE, Tuvim MJ, Dickey BF | Frontiers in pharmacology | 24567720 | Front Pharmacol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24567720 |
Fungal Pneumonia in Patients with Hematologic Malignancy and Hematopoietic Stem Cell Transplantation. | Young AY, Leiva Juarez MM, Evans SE | Clinics in chest medicine | 28797490 | Clin Chest Med | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28797490 |
Inducible epithelial resistance protects mice against leukemia-associated pneumonia. | Leiva-Juárez MM, Ware HH, Kulkarni VV, Zweidler-McKay PA, Tuvim MJ, Evans SE | Blood | 27317793 | Blood | 2016 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/27317793 |
Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial metabolic reprogramming. | Wang Y, Kulkarni VV, Pantaleón García J, Leiva-Juárez MM, Goldblatt DL, Gulraiz F, Chen J, Donepudi SR, Lorenzi PL, Wang H, Wong LJ, Tuvim MJ, Evans SE | bioRxiv : the preprint server for biology | 36711510 | bioRxiv | 2023 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/36711510 |
Redox-Dependent Activation of Lung Epithelial STAT3 Is Required for Inducible Protection against Bacterial Pneumonia. | Kulkarni VV, Wang Y, Pantaleon Garcia J, Evans SE | American journal of respiratory cell and molecular biology | 36826841 | Am J Respir Cell Mol Biol | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/36826841 |
Toll-like receptor-2/6 and Toll-like receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs. | Drake MG, Evans SE, Dickey BF, Fryer AD, Jacoby DB | American journal of respiratory cell and molecular biology | 23449736 | Am J Respir Cell Mol Biol | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23449736 |
Lung epithelial cells are essential effectors of inducible resistance to pneumonia. | Cleaver JO, You D, Michaud DR, Pruneda FA, Juarez MM, Zhang J, Weill PM, Adachi R, Gong L, Moghaddam SJ, Poynter ME, Tuvim MJ, Evans SE | Mucosal immunology | 23632328 | Mucosal Immunol | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/23632328 |
Porous silicon microparticle potentiates anti-tumor immunity by enhancing cross-presentation and inducing type I interferon response. | Xia X, Mai J, Xu R, Perez JET, Guevara ML, Shen Q, Mu C, Tung HY, Corry DB, Evans SE, Liu X, Ferrari M, Zhang Z, Li XC, Wang RF, Shen H | Cell reports | 25937283 | Cell Rep | 2015 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/25937283 |
Viral Pneumonia in Patients with Hematologic Malignancy or Hematopoietic Stem Cell Transplantation. | Vakil E, Evans SE | Clinics in chest medicine | 28159165 | Clin Chest Med | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28159165 |
A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo. | Covés-Datson EM, King SR, Legendre M, Gupta A, Chan SM, Gitlin E, Kulkarni VV, Pantaleón García J, Smee DF, Lipka E, Evans SE, Tarbet EB, Ono A, Markovitz DM | Proceedings of the National Academy of Sciences of the United States of America | 31932446 | Proc Natl Acad Sci U S A | 2020 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/31932446 |
Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections. | Kirkpatrick CT, Wang Y, Leiva Juarez MM, Shivshankar P, Pantaleón García J, Plumer AK, Kulkarni VV, Ware HH, Gulraiz F, Chavez Cavasos MA, Martinez Zayas G, Wali S, Rice AP, Liu H, Tour JM, Sikkema WKA, Cruz Solbes AS, Youker KA, Tuvim MJ, Dickey BF, Evans SE | mBio | 29764948 | mBio | 2018 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/29764948 |
Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against bacterial infections. | Ware HH, Kulkarni VV, Wang Y, Pantaleón García J, Leiva Juarez M, Kirkpatrick CT, Wali S, Syed S, Kontoyiannis AD, Sikkema WKA, Tour JM, Evans SE | PloS one | 30794556 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30794556 |
Immune Modulation to Improve Survival of Viral Pneumonia in Mice. | Wali S, Flores JR, Jaramillo AM, Goldblatt DL, Pantaleón García J, Tuvim MJ, Dickey BF, Evans SE | American journal of respiratory cell and molecular biology | 32853024 | Am J Respir Cell Mol Biol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32853024 |
Repetitive aeroallergen challenges elucidate maladaptive epithelial and inflammatory traits that underpin allergic airway diseases. | Smith AM, Harper N, Meunier JA, Branum AP, Jimenez F, Pandranki L, Carrillo A, Dela Cruz CS, Restrepo MI, Maselli DJ, Rather CG, Heisser AH, Ramirez DA, He W, Clark RA, Andrews CP, Evans SE, Pugh JA, Zhang N, Lee GC, Moreira AG, Segal LN, Ramirez RM, Jacobs RL, Manoharan MS, Okulicz JF, Ahuja SK | The Journal of allergy and clinical immunology | 33493557 | J Allergy Clin Immunol | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/33493557 |
The RNA receptor RIG-I binding synthetic oligodeoxynucleotide promotes pneumonia survival. | Wang Y, Kulkarni VV, PantaleónGarcía J, Longmire MK, Lethier M, Cusack S, Evans SE | JCI insight | 39352770 | JCI Insight | 2024 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/39352770 |
Alternative Splicing, Internal Promoter, Nonsense-Mediated Decay, or All Three: Explaining the Distribution of Truncation Variants in Titin. | Deo RC | Circulation. Cardiovascular genetics | 27625338 | Circ Cardiovasc Genet | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27625338 |
Response by Zhang and Deo to Letter Regarding Article, "Fully Automated Echocardiogram Interpretation in Clinical Practice: Feasibility and Diagnostic Accuracy". | Zhang J, Deo RC | Circulation | 30908098 | Circulation | 2019 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/30908098 |
An International Multicenter Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2-Catecholaminergic Polymorphic Ventricular Tachycardia. | Ng K, Titus EW, Lieve KV, Roston TM, Mazzanti A, Deiter FH, Denjoy I, Ingles J, Till J, Robyns T, Connors SP, Steinberg C, Abrams DJ, Pang B, Scheinman MM, Bos JM, Duffett SA, van der Werf C, Maltret A, Green MS, Rutberg J, Balaji S, Cadrin-Tourigny J, Orland KM, Knight LM, Brateng C, Wu J, Tang AS, Skanes AC, Manlucu J, Healey JS, January CT, Krahn AD, Collins KK, Maginot KR, Fischbach P, Etheridge SP, Eckhardt LL, Hamilton RM, Ackerman MJ, Noguer FRI, Semsarian C, Jura N, Leenhardt A, Gollob MH, Priori SG, Sanatani S, Wilde AAM, Deo RC, Roberts JD | Circulation | 32693635 | Circulation | 2020 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/32693635 |
Targeted deep sequencing reveals no definitive evidence for somatic mosaicism in atrial fibrillation. | Roberts JD, Longoria J, Poon A, Gollob MH, Dewland TA, Kwok PY, Olgin JE, Deo RC, Marcus GM | Circulation. Cardiovascular genetics | 25406240 | Circ Cardiovasc Genet | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25406240 |
Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary. | Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB | Circulation | 32202936 | Circulation | 2020 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/32202936 |
The structure of a calsequestrin filament reveals mechanisms of familial arrhythmia. | Titus EW, Deiter FH, Shi C, Wojciak J, Scheinman M, Jura N, Deo RC | Nature structural & molecular biology | 33046906 | Nat Struct Mol Biol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33046906 |
Learning About Machine Learning: The Promise and Pitfalls of Big Data and the Electronic Health Record. | Deo RC, Nallamothu BK | Circulation. Cardiovascular quality and outcomes | 28263936 | Circ Cardiovasc Qual Outcomes | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28263936 |
RNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells. | Vedantham V, Galang G, Evangelista M, Deo RC, Srivastava D | Circulation research | 25623957 | Circ Res | 2015 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/25623957 |
Prioritizing causal disease genes using unbiased genomic features. | Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok PY, MacRae CA, Roth FP | Genome biology | 25633252 | Genome Biol | 2014 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/25633252 |
Machine Learning in Medicine. | Deo RC | Circulation | 26572668 | Circulation | 2015 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/26572668 |
An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish. | Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC | eLife | 26473617 | Elife | 2015 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/26473617 |
Automated and Interpretable Patient ECG Profiles for Disease Detection, Tracking, and Discovery. | Tison GH, Zhang J, Delling FN, Deo RC | Circulation. Cardiovascular quality and outcomes | 31525078 | Circ Cardiovasc Qual Outcomes | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31525078 |
Precision Phenotyping of Dilated Cardiomyopathy Using Multidimensional Data. | Tayal U, Verdonschot JAJ, Hazebroek MR, Howard J, Gregson J, Newsome S, Gulati A, Pua CJ, Halliday BP, Lota AS, Buchan RJ, Whiffin N, Kanapeckaite L, Baruah R, Jarman JWE, O'Regan DP, Barton PJR, Ware JS, Pennell DJ, Adriaans BP, Bekkers SCAM, Donovan J, Frenneaux M, Cooper LT, Januzzi JL Jr, Cleland JGF, Cook SA, Deo RC, Heymans SRB, Prasad SK | Journal of the American College of Cardiology | 35654493 | J Am Coll Cardiol | 2022 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/35654493 |
Phenomapping for novel classification of heart failure with preserved ejection fraction. | Shah SJ, Katz DH, Selvaraj S, Burke MA, Yancy CW, Gheorghiade M, Bonow RO, Huang CC, Deo RC | Circulation | 25398313 | Circulation | 2015 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/25398313 |
Regulatory constraints in the generation and differentiation of IgE-expressing B cells. | Yang Z, Robinson MJ, Allen CD | Current opinion in immunology | 24632082 | Curr Opin Immunol | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24632082 |
Expression of Exogenous Genes in Murine Primary B Cells and B Cell Lines Using Retroviral Vectors. | Yang Z, Allen CDC | Methods in molecular biology (Clifton, N.J.) | 29388098 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29388098 |
A case of mistaken identity: The MAR-1 antibody to mouse FcεRIα cross-reacts with FcγRI and FcγRIV. | Tang XZ, Jung JB, Allen CDC | The Journal of allergy and clinical immunology | 30639345 | J Allergy Clin Immunol | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30639345 |
Study of IgE-Producing B Cells Using the Verigem Fluorescent Reporter Mouse. | Yang Z, Jung JB, Allen CDC | Methods in molecular biology (Clifton, N.J.) | 29956157 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29956157 |
Integrin α2β1 regulates collagen I tethering to modulate hyperresponsiveness in reactive airway disease models. | Liu S, Ngo U, Tang XZ, Ren X, Qiu W, Huang X, DeGrado W, Allen CD, Jo H, Sheppard D, Sundaram AB | The Journal of clinical investigation | 33956668 | J Clin Invest | 2021 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/33956668 |
Macrophage Cx43 Is Necessary for Fibroblast Cytosolic Calcium and Lung Fibrosis After Injury. | Bhattacharyya A, Torre P, Yadav P, Boostanpour K, Chen TY, Tsukui T, Sheppard D, Muramatsu R, Seed RI, Nishimura SL, Jung JB, Tang XZ, Allen CDC, Bhattacharya M | Frontiers in immunology | 35634278 | Front Immunol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35634278 |
Bronchus-associated macrophages efficiently capture and present soluble inhaled antigens and are capable of local Th2 cell activation. | Tang XZ, Kreuk LSM, Cho C, Metzger RJ, Allen CDC | eLife | 36173678 | Elife | 2022 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/36173678 |
Fabrication of freestanding alginate microfibers and microstructures for tissue engineering applications. | Szymanski JM, Feinberg AW | Biofabrication | 24695323 | Biofabrication | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24695323 |
Extracellular Matrix Structure and Composition in the Early Four-Chambered Embryonic Heart. | Jallerat Q, Feinberg AW | Cells | 31991580 | Cells | 2020 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/31991580 |
Measuring the Poisson's Ratio of Fibronectin Using Engineered Nanofibers. | Szymanski JM, Zhang K, Feinberg AW | Scientific reports | 29042643 | Sci Rep | 2017 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/29042643 |
Fibronectin-based nanomechanical biosensors to map 3D surface strains in live cells and tissue. | Shiwarski DJ, Tashman JW, Tsamis A, Bliley JM, Blundon MA, Aranda-Michel E, Jallerat Q, Szymanski JM, McCartney BM, Feinberg AW | Nature communications | 33208732 | Nat Commun | 2020 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/33208732 |
3D Printing PDMS Elastomer in a Hydrophilic Support Bath via Freeform Reversible Embedding. | Hinton TJ, Hudson A, Pusch K, Lee A, Feinberg AW | ACS biomaterials science & engineering | 27747289 | ACS Biomater Sci Eng | 2016 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/27747289 |
Shrink Wrapping Cells in a Defined Extracellular Matrix to Modulate the Chemo-Mechanical Microenvironment. | Palchesko RN, Szymanski JM, Sahu A, Feinberg AW | Cellular and molecular bioengineering | 25530816 | Cell Mol Bioeng | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25530816 |
In vitro expansion of corneal endothelial cells on biomimetic substrates. | Palchesko RN, Lathrop KL, Funderburgh JL, Feinberg AW | Scientific reports | 25609008 | Sci Rep | 2015 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/25609008 |
Cryopreserved cell-laden alginate microgel bioink for 3D bioprinting of living tissues. | Jeon O, Bin Lee Y, Hinton TJ, Feinberg AW, Alsberg E | Materials today. Chemistry | 30778400 | Mater Today Chem | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30778400 |
ECM protein nanofibers and nanostructures engineered using surface-initiated assembly. | Szymanski JM, Jallerat Q, Feinberg AW | Journal of visualized experiments : JoVE | 24799041 | J Vis Exp | 2014 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/24799041 |
Engineering Aligned Skeletal Muscle Tissue Using Decellularized Plant-Derived Scaffolds. | Cheng YW, Shiwarski DJ, Ball RL, Whitehead KA, Feinberg AW | ACS biomaterials science & engineering | 33463300 | ACS Biomater Sci Eng | 2020 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/33463300 |
Conformal nanopatterning of extracellular matrix proteins onto topographically complex surfaces. | Sun Y, Jallerat Q, Szymanski JM, Feinberg AW | Nature methods | 25506720 | Nat Methods | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25506720 |
Stretch-dependent changes in molecular conformation in fibronectin nanofibers. | Szymanski JM, Sevcik EN, Zhang K, Feinberg AW | Biomaterials science | 28612067 | Biomater Sci | 2017 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/28612067 |
Engineered Basement Membranes for Regenerating the Corneal Endothelium. | Palchesko RN, Funderburgh JL, Feinberg AW | Advanced healthcare materials | 27723276 | Adv Healthc Mater | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27723276 |
Understanding the Role of ECM Protein Composition and Geometric Micropatterning for Engineering Human Skeletal Muscle. | Duffy RM, Sun Y, Feinberg AW | Annals of biomedical engineering | 26983843 | Ann Biomed Eng | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26983843 |
Spontaneous Helical Structure Formation in Laminin Nanofibers. | Szymanski JM, Ba M, Feinberg AW | Journal of materials chemistry. B | 26693018 | J Mater Chem B | 2015 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/26693018 |
3D bioprinting of collagen to rebuild components of the human heart. | Lee A, Hudson AR, Shiwarski DJ, Tashman JW, Hinton TJ, Yerneni S, Bliley JM, Campbell PG, Feinberg AW | Science (New York, N.Y.) | 31371612 | Science | 2019 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/31371612 |
Engineering aligned human cardiac muscle using developmentally inspired fibronectin micropatterns. | Batalov I, Jallerat Q, Kim S, Bliley J, Feinberg AW | Scientific reports | 34075068 | Sci Rep | 2021 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/34075068 |
Patterning on Topography for Generation of Cell Culture Substrates with Independent Nanoscale Control of Chemical and Topographical Extracellular Matrix Cues. | Sevcik EN, Szymanski JM, Jallerat Q, Feinberg AW | Current protocols in cell biology | 28627752 | Curr Protoc Cell Biol | 2017 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/28627752 |
Large volume syringe pump extruder for desktop 3D printers. | Pusch K, Hinton TJ, Feinberg AW | HardwareX | 30498799 | HardwareX | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30498799 |
Three-dimensional printing of complex biological structures by freeform reversible embedding of suspended hydrogels. | Hinton TJ, Jallerat Q, Palchesko RN, Park JH, Grodzicki MS, Shue HJ, Ramadan MH, Hudson AR, Feinberg AW | Science advances | 26601312 | Sci Adv | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26601312 |
Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype. | Bliley JM, Vermeer MCSC, Duffy RM, Batalov I, Kramer D, Tashman JW, Shiwarski DJ, Lee A, Teplenin AS, Volkers L, Coffin B, Hoes MF, Kalmykov A, Palchesko RN, Sun Y, Jongbloed JDH, Bomer N, de Boer RA, Suurmeijer AJH, Pijnappels DA, Bolling MC, van der Meer P, Feinberg AW | Science translational medicine | 34290054 | Sci Transl Med | 2021 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/34290054 |
Engineering artificial cells by combining HeLa-based cell-free expression and ultrathin double emulsion template. | Ho KK, Murray VL, Liu AP | Methods in cell biology | 25997354 | Methods Cell Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25997354 |
Cell-sized mechanosensitive and biosensing compartment programmed with DNA. | Majumder S, Garamella J, Wang YL, DeNies M, Noireaux V, Liu AP | Chemical communications (Cambridge, England) | 28524182 | Chem Commun (Camb) | 2017 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/28524182 |
Development of an advanced microfluidic micropipette aspiration device for single cell mechanics studies. | Lee LM, Lee JW, Chase D, Gebrezgiabhier D, Liu AP | Biomicrofluidics | 27703591 | Biomicrofluidics | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27703591 |
Synergistic and non-specific nucleic acid production by T7 RNA polymerase and Bsu DNA polymerase catalyzed by single-stranded polynucleotides. | Emery NJ, Majumder S, Liu AP | Synthetic and systems biotechnology | 29900426 | Synth Syst Biotechnol | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29900426 |
Cofactoring and dimerization of proteinase-activated receptors. | Lin H, Liu AP, Smith TH, Trejo J | Pharmacological reviews | 24064459 | Pharmacol Rev | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24064459 |
The rise of bottom-up synthetic biology and cell-free biology. | Liu AP | Physical biology | 31018188 | Phys Biol | 2019 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/31018188 |
Bottom-up synthetic biology: modular design for making artificial platelets. | Majumder S, Liu AP | Physical biology | 29091050 | Phys Biol | 2017 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/29091050 |
Uniaxial cell stretching device for live-cell imaging of mechanosensitive cellular functions. | Shao Y, Tan X, Novitski R, Muqaddam M, List P, Williamson L, Fu J, Liu AP | The Review of scientific instruments | 24289415 | Rev Sci Instrum | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/24289415 |
Lipid bilayer vesicle generation using microfluidic jetting. | Coyne CW, Patel K, Heureaux J, Stachowiak J, Fletcher DA, Liu AP | Journal of visualized experiments : JoVE | 24637415 | J Vis Exp | 2014 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/24637415 |
Advanced Microfluidic Device Designed for Cyclic Compression of Single Adherent Cells. | Ho KKY, Wang YL, Wu J, Liu AP | Frontiers in bioengineering and biotechnology | 30386779 | Front Bioeng Biotechnol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30386779 |
Biophysical Tools for Cellular and Subcellular Mechanical Actuation of Cell Signaling. | Liu AP | Biophysical journal | 27456131 | Biophys J | 2016 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/27456131 |
Multiplex detection of homo- and heterodimerization of g protein-coupled receptors by proximity biotinylation. | Steel E, Murray VL, Liu AP | PloS one | 24691126 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24691126 |
Mechanically activated artificial cell by using microfluidics. | Ho KK, Lee LM, Liu AP | Scientific reports | 27610921 | Sci Rep | 2016 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/27610921 |
Simultaneous monitoring of transcription and translation in mammalian cell-free expression in bulk and in cell-sized droplets. | Wang S, Majumder S, Emery NJ, Liu AP | Synthetic biology (Oxford, England) | 30003145 | Synth Biol (Oxf) | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30003145 |
Protein aggregation with poly(vinyl) alcohol surfactant reduces double emulsion-encapsulated mammalian cell-free expression. | Ho KK, Lee JW, Durand G, Majumder S, Liu AP | PloS one | 28358875 | PLoS One | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28358875 |
Cell-free compartmentalized protein synthesis inside double emulsion templated liposomes with in vitro synthesized and assembled ribosomes. | Caschera F, Lee JW, Ho KK, Liu AP, Jewett MC | Chemical communications (Cambridge, England) | 27019994 | Chem Commun (Camb) | 2016 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/27019994 |
Activation of a bacterial mechanosensitive channel in mammalian cells by cytoskeletal stress. | Heureaux J, Chen D, Murray VL, Deng CX, Liu AP | Cellular and molecular bioengineering | 25606062 | Cell Mol Bioeng | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25606062 |
A microfluidic pipette array for mechanophenotyping of cancer cells and mechanical gating of mechanosensitive channels. | Lee LM, Liu AP | Lab on a chip | 25361042 | Lab Chip | 2015 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/25361042 |
The Application of Micropipette Aspiration in Molecular Mechanics of Single Cells. | Lee LM, Liu AP | Journal of nanotechnology in engineering and medicine | 26155329 | J Nanotechnol Eng Med | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26155329 |
Sonographic evidence of abnormal tracheal cartilage ring structure in cystic fibrosis. | Diwakar A, Adam RJ, Michalski AS, Tamegnon MM, Fischer AJ, Launspach JL, Horan RA, Kao SC, Chaloner K, Meyerholz DK, Stoltz DA | The Laryngoscope | 25827636 | Laryngoscope | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25827636 |
CF airway smooth muscle transcriptome reveals a role for PYK2. | Cook DP, Adam RJ, Zarei K, Deonovic B, Stroik MR, Gansemer ND, Meyerholz DK, Au KF, Stoltz DA | JCI insight | 28878137 | JCI Insight | 2017 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/28878137 |
Air trapping and airflow obstruction in newborn cystic fibrosis piglets. | Adam RJ, Michalski AS, Bauer C, Abou Alaiwa MH, Gross TJ, Awadalla MS, Bouzek DC, Gansemer ND, Taft PJ, Hoegger MJ, Diwakar A, Ochs M, Reinhardt JM, Hoffman EA, Beichel RR, Meyerholz DK, Stoltz DA | American journal of respiratory and critical care medicine | 24168209 | Am J Respir Crit Care Med | 2013 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/24168209 |
Airway acidification initiates host defense abnormalities in cystic fibrosis mice. | Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB Jr, Ostedgaard LS, Stoltz DA, Randak CO, Welsh MJ | Science (New York, N.Y.) | 26823428 | Science | 2016 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/26823428 |
Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs. | Hoegger MJ, Awadalla M, Namati E, Itani OA, Fischer AJ, Tucker AJ, Adam RJ, McLennan G, Hoffman EA, Stoltz DA, Welsh MJ | Proceedings of the National Academy of Sciences of the United States of America | 24474805 | Proc Natl Acad Sci U S A | 2014 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/24474805 |
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. | Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Abou Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, Wallen TJ, Wohlford-Lenane C, McMenimen JD, Chen JH, Bogan KL, Adam RJ, Hornick EE, Nelson GA 4th, Hoffman EA, Chang EH, Zabner J, McCray PB Jr, Prather RS, Meyerholz DK, Welsh MJ | The Journal of clinical investigation | 23676501 | J Clin Invest | 2013 Jun | https://www.ncbi.nlm.nih.gov/pubmed/23676501 |
Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans. | Meyerholz DK, Lambertz AM, Reznikov LR, Ofori-Amanfo GK, Karp PH, McCray PB Jr, Welsh MJ, Stoltz DA | Toxicologic pathology | 26511846 | Toxicol Pathol | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26511846 |
Cystic Fibrosis Transmembrane Conductance Regulator in Sarcoplasmic Reticulum of Airway Smooth Muscle. Implications for Airway Contractility. | Cook DP, Rector MV, Bouzek DC, Michalski AS, Gansemer ND, Reznikov LR, Li X, Stroik MR, Ostedgaard LS, Abou Alaiwa MH, Thompson MA, Prakash YS, Krishnan R, Meyerholz DK, Seow CY, Stoltz DA | American journal of respiratory and critical care medicine | 26488271 | Am J Respir Crit Care Med | 2016 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/26488271 |
Acidic pH increases airway surface liquid viscosity in cystic fibrosis. | Tang XX, Ostedgaard LS, Hoegger MJ, Moninger TO, Karp PH, McMenimen JD, Choudhury B, Varki A, Stoltz DA, Welsh MJ | The Journal of clinical investigation | 26808501 | J Clin Invest | 2016 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26808501 |
Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis. | Hoegger MJ, Fischer AJ, McMenimen JD, Ostedgaard LS, Tucker AJ, Awadalla MA, Moninger TO, Michalski AS, Hoffman EA, Zabner J, Stoltz DA, Welsh MJ | Science (New York, N.Y.) | 25124441 | Science | 2014 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/25124441 |
Gel-forming mucins form distinct morphologic structures in airways. | Ostedgaard LS, Moninger TO, McMenimen JD, Sawin NM, Parker CP, Thornell IM, Powers LS, Gansemer ND, Bouzek DC, Cook DP, Meyerholz DK, Abou Alaiwa MH, Stoltz DA, Welsh MJ | Proceedings of the National Academy of Sciences of the United States of America | 28607090 | Proc Natl Acad Sci U S A | 2017 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/28607090 |
Origins of cystic fibrosis lung disease. | Stoltz DA, Meyerholz DK, Welsh MJ | The New England journal of medicine | 25607428 | N Engl J Med | 2015 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/25607428 |
Mucociliary Transport in Healthy and Cystic Fibrosis Pig Airways. | Xie Y, Ostedgaard L, Abou Alaiwa MH, Lu L, Fischer AJ, Stoltz DA | Annals of the American Thoracic Society | 30431346 | Ann Am Thorac Soc | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30431346 |
Polarizing pathways: balancing endothelial polarity, permeability, and lumen formation. | Lizama CO, Zovein AC | Experimental cell research | 23567183 | Exp Cell Res | 2013 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/23567183 |
Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice. | Jiang X, Hawkins JS, Lee J, Lizama CO, Bos FL, Zape JP, Ghatpande P, Peng Y, Louie J, Lagna G, Zovein AC, Hata A | Nature communications | 28743859 | Nat Commun | 2017 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/28743859 |
Single-cell resolution of morphological changes in hemogenic endothelium. | Bos FL, Hawkins JS, Zovein AC | Development (Cambridge, England) | 26243871 | Development | 2015 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/26243871 |
Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition. | Lizama CO, Hawkins JS, Schmitt CE, Bos FL, Zape JP, Cautivo KM, Borges Pinto H, Rhyner AM, Yu H, Donohoe ME, Wythe JD, Zovein AC | Nature communications | 26204127 | Nat Commun | 2015 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/26204127 |
Cell cycle dynamics and complement expression distinguishes mature haematopoietic subsets arising from hemogenic endothelium. | Zape JP, Lizama CO, Cautivo KM, Zovein AC | Cell cycle (Georgetown, Tex.) | 28820341 | Cell Cycle | 2017 Oct 2 | https://www.ncbi.nlm.nih.gov/pubmed/28820341 |
Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart. | Ma XR, Conley SD, Kosicki M, Bredikhin D, Cui R, Tran S, Sheth MU, Qiu WL, Chen S, Kundu S, Kang HY, Amgalan D, Munger CJ, Duan L, Dang K, Rubio OM, Kany S, Zamirpour S, DePaolo J, Padmanabhan A, Birth Defects Research Laboratory, Olgin J, Damrauer S, Andersson R, Gu M, Priest JR, Quertermous T, Qiu X, Rabinovitch M, Visel A, Pennacchio L, Kundaje A, Glass IA, Gifford CA, Pirruccello JP, Goodyer WR, Engreitz JM | medRxiv : the preprint server for health sciences | 39606363 | medRxiv | 2024 Nov 22 | https://www.ncbi.nlm.nih.gov/pubmed/39606363 |
A Panoramic View of Cell Population Dynamics in Mammalian Aging. | Zhang Z, Schaefer C, Jiang W, Lu Z, Lee J, Sziraki A, Abdulraouf A, Wick B, Haeussler M, Li Z, Molla G, Satija R, Zhou W, Cao J | bioRxiv : the preprint server for biology | 38496474 | bioRxiv | 2024 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/38496474 |
Tracking cell-type-specific temporal dynamics in human and mouse brains. | Lu Z, Zhang M, Lee J, Sziraki A, Anderson S, Zhang Z, Xu Z, Jiang W, Ge S, Nelson PT, Zhou W, Cao J | Cell | 37774676 | Cell | 2023 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/37774676 |
Single-cell, whole-embryo phenotyping of mammalian developmental disorders. | Huang X, Henck J, Qiu C, Sreenivasan VKA, Balachandran S, Amarie OV, Hrabě de Angelis M, Behncke RY, Chan WL, Despang A, Dickel DE, Duran M, Feuchtinger A, Fuchs H, Gailus-Durner V, Haag N, Hägerling R, Hansmeier N, Hennig F, Marshall C, Rajderkar S, Ringel A, Robson M, Saunders LM, da Silva-Buttkus P, Spielmann N, Srivatsan SR, Ulferts S, Wittler L, Zhu Y, Kalscheuer VM, Ibrahim DM, Kurth I, Kornak U, Visel A, Pennacchio LA, Beier DR, Trapnell C, Cao J, Shendure J, Spielmann M | Nature | 37968388 | Nature | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37968388 |
A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains. | Sziraki A, Lu Z, Lee J, Banyai G, Anderson S, Abdulraouf A, Metzner E, Liao A, Banfelder J, Epstein A, Schaefer C, Xu Z, Zhang Z, Gan L, Nelson PT, Zhou W, Cao J | Nature genetics | 38036784 | Nat Genet | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/38036784 |
Optics-free Spatial Genomics for Mapping Mouse Brain Aging. | Abdulraouf A, Jiang W, Xu Z, Zhang Z, Isakov S, Raihan T, Zhou W, Cao J | bioRxiv : the preprint server for biology | 39149282 | bioRxiv | 2024 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/39149282 |
Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens. | Xu Z, Sziraki A, Lee J, Zhou W, Cao J | Nature biotechnology | 37749268 | Nat Biotechnol | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37749268 |
A panoramic view of cell population dynamics in mammalian aging. | Zhang Z, Schaefer C, Jiang W, Lu Z, Lee J, Sziraki A, Abdulraouf A, Wick B, Haeussler M, Li Z, Molla G, Satija R, Zhou W, Cao J | Science (New York, N.Y.) | 39607904 | Science | 2025 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/39607904 |
Early peanut introduction wins over the HLA-DQA1*01:02 allele in the interplay between environment and genetics. | Manohar M, Nadeau KC, Kasowski M | The Journal of clinical investigation | 34981779 | J Clin Invest | 2022 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/34981779 |
Condensate-Promoting ENL Mutation Drives Tumorigenesis In Vivo Through Dynamic Regulation of Histone Modifications and Gene Expression. | Liu Y, Li Q, Song L, Gong C, Tang S, Budinich KA, Vanderbeck A, Mathias KM, Wertheim GB, Nguyen SC, Outen R, Joyce EF, Maillard I, Wan L | Cancer discovery | 38655899 | Cancer Discov | 2024 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/38655899 |
DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance. | Zhou N, Choi J, Grothusen G, Kim BJ, Ren D, Cao Z, Liu Y, Li Q, Inamdar A, Beer T, Tang HY, Perkey E, Maillard I, Bonasio R, Shi J, Ruella M, Wan L, Busino L | Blood | 37235754 | Blood | 2023 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/37235754 |
Dysregulation of transcriptional condensates in human disease: mechanisms, biological functions, and open questions. | Mathias KM, Liu Y, Wan L | Current opinion in genetics & development | 38788489 | Curr Opin Genet Dev | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38788489 |
Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia. | Wang XQD, Fan D, Han Q, Liu Y, Miao H, Wang X, Li Q, Chen D, Gore H, Himadewi P, Pfeifer GP, Cierpicki T, Grembecka J, Su J, Chong S, Wan L, Zhang X | Cancer discovery | 36455589 | Cancer Discov | 2023 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/36455589 |
Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. | Song L, Yao X, Li H, Peng B, Boka AP, Liu Y, Chen G, Liu Z, Mathias KM, Xia L, Li Q, Mir M, Li Y, Li H, Wan L | Molecular cell | 36272410 | Mol Cell | 2022 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/36272410 |
Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia. | Liu Y, Li Q, Alikarami F, Barrett DR, Mahdavi L, Li H, Tang S, Khan TA, Michino M, Hill C, Song L, Yang L, Li Y, Pokharel SP, Stamford AW, Liverton N, Renzetti LM, Taylor S, Watt GF, Ladduwahetty T, Kargman S, Meinke PT, Foley MA, Shi J, Li H, Carroll M, Chen CW, Gardini A, Maillard I, Huggins DJ, Bernt KM, Wan L | Cancer discovery | 36053276 | Cancer Discov | 2022 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/36053276 |
Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape. | Song L, Li Q, Xia L, Sahay AE, Qiu Q, Li Y, Li H, Sasaki K, Susztak K, Wu H, Wan L | Nature communications | 39009564 | Nat Commun | 2024 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/39009564 |
HMGB1 restores a dynamic chromatin environment in the presence of linker histone by deforming nucleosomal DNA. | Saunders HS, Chio US, Moore CM, Ramani V, Cheng Y, Narlikar GJ | bioRxiv : the preprint server for biology | 39229246 | bioRxiv | 2024 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/39229246 |
Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers. | Yang MG, Richter HJ, Wang S, McNally CP, Harris N, Dhillon S, Maresca M, de Wit E, Willenbring H, Maher J, Goodarzi H, Ramani V | bioRxiv : the preprint server for biology | 39896524 | bioRxiv | 2025 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/39896524 |
Nucleosome density shapes kilobase-scale regulation by a mammalian chromatin remodeler. | Abdulhay NJ, Hsieh LJ, McNally CP, Ostrowski MS, Moore CM, Ketavarapu M, Kasinathan S, Nanda AS, Wu K, Chio US, Zhou Z, Goodarzi H, Narlikar GJ, Ramani V | Nature structural & molecular biology | 37696956 | Nat Struct Mol Biol | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37696956 |
A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies. | Freie B, Carroll PA, Varnum-Finney BJ, Ramsey EL, Ramani V, Bernstein I, Eisenman RN | Genes & development | 38565249 | Genes Dev | 2024 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/38565249 |
ATP-dependent remodeling of chromatin condensates uncovers distinct mesoscale effects of two remodelers. | Moore C, Wong E, Kaur U, Chio US, Zhou Z, Ostrowski M, Wu K, Irkliyenko I, Wang S, Ramani V, Narlikar GJ | bioRxiv : the preprint server for biology | 39314305 | bioRxiv | 2024 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/39314305 |
Direct transposition of native DNA for sensitive multimodal single-molecule sequencing. | Nanda AS, Wu K, Irkliyenko I, Woo B, Ostrowski MS, Clugston AS, Sayles LC, Xu L, Satpathy AT, Nguyen HG, Alejandro Sweet-Cordero E, Goodarzi H, Kasinathan S, Ramani V | Nature genetics | 38724748 | Nat Genet | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38724748 |
A Germline Point Mutation in the MYC-FBW7 Phosphodegron Initiates Hematopoietic Malignancies. | Freie B, Carroll PA, Varnum-Finney BJ, Ramani V, Bernstein I, Eisenman RN | bioRxiv : the preprint server for biology | 37961183 | bioRxiv | 2023 Oct 25 | https://www.ncbi.nlm.nih.gov/pubmed/37961183 |
The Long Noncoding RNA PRANCR Is Associated with Alternative Splicing of Fibronectin-1 in Keratinocytes. | Otten ABC, Amarbayar O, Cai P, Cheng B, Qu K, Sun BK | The Journal of investigative dermatology | 36906126 | J Invest Dermatol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36906126 |
Alternative mRNA splicing events and regulators in epidermal differentiation. | Takashima S, Sun W, Otten ABC, Cai P, Peng SI, Tong E, Bui J, Mai M, Amarbayar O, Cheng B, Odango RJ, Li Z, Qu K, Sun BK | Cell reports | 38402585 | Cell Rep | 2024 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/38402585 |
The role of enhancers in psoriasis and atopic dermatitis. | Sui JY, Eichenfield DZ, Sun BK | The British journal of dermatology | 37658835 | Br J Dermatol | 2023 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/37658835 |
Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. | Hoffmann FT, Kim M, Beh LY, Wang J, Vo PLH, Gelsinger DR, George JT, Acree C, Mohabir JT, Fernández IS, Sternberg SH | Nature | 36002573 | Nature | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36002573 |
Transposon-encoded nucleases use guide RNAs to promote their selfish spread. | Meers C, Le HC, Pesari SR, Hoffmann FT, Walker MWG, Gezelle J, Tang S, Sternberg SH | Nature | 37758954 | Nature | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37758954 |
Novel molecular requirements for CRISPR RNA-guided transposition. | Walker MWG, Klompe SE, Zhang DJ, Sternberg SH | Nucleic acids research | 37078593 | Nucleic Acids Res | 2023 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/37078593 |
Mechanism of target site selection by type V-K CRISPR-associated transposases. | George JT, Acree C, Park JU, Kong M, Wiegand T, Pignot YL, Kellogg EH, Greene EC, Sternberg SH | bioRxiv : the preprint server for biology | 37503092 | bioRxiv | 2023 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/37503092 |
Bacterial genome engineering using CRISPR RNA-guided transposases. | Gelsinger DR, Vo PLH, Klompe SE, Ronda C, Wang H, Sternberg SH | bioRxiv : the preprint server for biology | 36993567 | bioRxiv | 2023 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/36993567 |
TnpB homologues exapted from transposons are RNA-guided transcription factors. | Wiegand T, Hoffmann FT, Walker MWG, Tang S, Richard E, Le HC, Meers C, Sternberg SH | Nature | 38926585 | Nature | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38926585 |
Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells. | Lampe GD, Liang AR, Zhang DJ, Fernández IS, Sternberg SH | bioRxiv : the preprint server for biology | 39345383 | bioRxiv | 2024 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/39345383 |
Novel recombinases for large DNA insertions. | Lampe GD, Sternberg SH | Nature biotechnology | 36424492 | Nat Biotechnol | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36424492 |
Transposon mutagenesis libraries reveal novel molecular requirements during CRISPR RNA-guided DNA integration. | Walker MWG, Klompe SE, Zhang DJ, Sternberg SH | bioRxiv : the preprint server for biology | 36711804 | bioRxiv | 2023 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/36711804 |
Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases. | Lampe GD, King RT, Halpin-Healy TS, Klompe SE, Hogan MI, Vo PLH, Tang S, Chavez A, Sternberg SH | Nature biotechnology | 36991112 | Nat Biotechnol | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36991112 |
Evolutionary origins of archaeal and eukaryotic RNA-guided RNA modification in bacterial IS110 transposons. | Vaysset H, Meers C, Cury J, Bernheim A, Sternberg SH | Nature microbiology | 39747689 | Nat Microbiol | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39747689 |
Unbiased profiling of CRISPR RNA-guided transposition products by long-read sequencing. | Vo PLH, Acree C, Smith ML, Sternberg SH | Mobile DNA | 34103093 | Mob DNA | 2021 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/34103093 |
Evolutionary and mechanistic diversity of Type I-F CRISPR-associated transposons. | Klompe SE, Jaber N, Beh LY, Mohabir JT, Bernheim A, Sternberg SH | Molecular cell | 35051352 | Mol Cell | 2022 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/35051352 |
Mechanism of target site selection by type V-K CRISPR-associated transposases. | George JT, Acree C, Park JU, Kong M, Wiegand T, Pignot YL, Kellogg EH, Greene EC, Sternberg SH | Science (New York, N.Y.) | 37972161 | Science | 2023 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/37972161 |
Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases. | Lampe GD, King RT, Halpin-Healy TS, Klompe SE, Hogan MI, Vo PLH, Tang S, Chavez A, Sternberg SH | bioRxiv : the preprint server for biology | 36993517 | bioRxiv | 2023 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/36993517 |
Genome editing with retroelements. | Tang S, Sternberg SH | Science (New York, N.Y.) | 37883564 | Science | 2023 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/37883564 |
Bacterial genome engineering using CRISPR-associated transposases. | Gelsinger DR, Vo PLH, Klompe SE, Ronda C, Wang HH, Sternberg SH | Nature protocols | 38216671 | Nat Protoc | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38216671 |
De novo gene synthesis by an antiviral reverse transcriptase. | Tang S, Conte V, Zhang DJ, Žedaveinytė R, Lampe GD, Wiegand T, Tang LC, Wang M, Walker MWG, George JT, Berchowitz LE, Jovanovic M, Sternberg SH | Science (New York, N.Y.) | 39116258 | Science | 2024 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/39116258 |
Antagonistic conflict between transposon-encoded introns and guide RNAs. | Žedaveinytė R, Meers C, Le HC, Mortman EE, Tang S, Lampe GD, Pesari SR, Gelsinger DR, Wiegand T, Sternberg SH | Science (New York, N.Y.) | 38991068 | Science | 2024 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/38991068 |
Geared Toward Applications: A Perspective on Functional Sequence-Controlled Polymers. | Yang C, Wu KB, Deng Y, Yuan J, Niu J | ACS macro letters | 34336395 | ACS Macro Lett | 2021 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/34336395 |
Harnessing the power of directed evolution to improve genome editing systems. | Su Q, Zhou M, Cheng C, Niu J | Current opinion in chemical biology | 33725650 | Curr Opin Chem Biol | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33725650 |
A General Approach to O-Sulfation by a Sulfur(VI) Fluoride Exchange Reaction. | Liu C, Yang C, Hwang S, Ferraro SL, Flynn JP, Niu J | Angewandte Chemie (International ed. in English) | 32644280 | Angew Chem Int Ed Engl | 2020 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/32644280 |
Fluorosulfate as a Latent Sulfate in Peptides and Proteins. | Liu C, Liu X, Zhou M, Xia C, Lyu Y, Peng Q, Soni C, Zhou Z, Su Q, Wu Y, Weerapana E, Gao J, Chatterjee A, Lin C, Niu J | Journal of the American Chemical Society | 37647087 | J Am Chem Soc | 2023 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/37647087 |
Genome editor-directed in vivo library diversification. | Cheng C, Zhou M, Su Q, Steigmeyer A, Niu J | Cell chemical biology | 34107297 | Cell Chem Biol | 2021 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/34107297 |
"Click handle"-modified 2'-deoxy-2'-fluoroarabino nucleic acid as a synthetic genetic polymer capable of post-polymerization functionalization. | Wu KB, Skrodzki CJA, Su Q, Lin J, Niu J | Chemical science | 35774169 | Chem Sci | 2022 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/35774169 |
Heparan sulfate glycomimetics via iterative assembly of "clickable" disaccharides. | Yang C, Deng Y, Wang Y, Xia C, Mehta AY, Baker KJ, Samal A, Booneimsri P, Lertmaneedang C, Hwang S, Flynn JP, Cao M, Liu C, Zhu AC, Cummings RD, Lin C, Mohanty U, Niu J | Chemical science | 37006675 | Chem Sci | 2023 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/37006675 |
Origin recognition complex harbors an intrinsic nucleosome remodeling activity. | Li S, Wasserman MR, Yurieva O, Bai L, O'Donnell ME, Liu S | Proceedings of the National Academy of Sciences of the United States of America | 36215487 | Proc Natl Acad Sci U S A | 2022 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/36215487 |
Structure and DNA bridging activity of the essential Rec114â€"Mei4 trimer interface. | Liu K, Grasso EM, Pu S, Liu S, Eliezer D, Keeney S | bioRxiv : the preprint server for biology | 36711595 | bioRxiv | 2023 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/36711595 |
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. | Abini-Agbomson S, Gretarsson K, Shih RM, Hsieh L, Lou T, De Ioannes P, Vasilyev N, Lee R, Wang M, Simon M, Armache JP, Nudler E, Narlikar G, Liu S, Lu C, Armache KJ | bioRxiv : the preprint server for biology | 36993485 | bioRxiv | 2023 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/36993485 |
Structure and DNA-bridging activity of the essential Rec114-Mei4 trimer interface. | Liu K, Grasso EM, Pu S, Zou M, Liu S, Eliezer D, Keeney S | Genes & development | 37442580 | Genes Dev | 2023 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/37442580 |
Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes. | Chua GNL, Watters JW, Olinares PDB, Luo JA, Chait BT, Liu S | bioRxiv : the preprint server for biology | 37333354 | bioRxiv | 2023 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/37333354 |
Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination. | Wang L, Watters JW, Ju X, Lu G, Liu S | Molecular cell | 36917983 | Mol Cell | 2023 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/36917983 |
Nonreciprocal and Conditional Cooperativity Directs the Pioneer Activity of Pluripotency Transcription Factors. | Li S, Zheng EB, Zhao L, Liu S | Cell reports | 31484078 | Cell Rep | 2019 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/31484078 |
Cooperative DNA looping by PRC2 complexes. | Lin X, Leicher R, Liu S, Zhang B | Nucleic acids research | 34057467 | Nucleic Acids Res | 2021 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/34057467 |
Single-stranded nucleic acid binding and coacervation by linker histone H1. | Leicher R, Osunsade A, Chua GNL, Faulkner SC, Latham AP, Watters JW, Nguyen T, Beckwitt EC, Christodoulou-Rubalcava S, Young PG, Zhang B, David Y, Liu S | Nature structural & molecular biology | 35484234 | Nat Struct Mol Biol | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35484234 |
Optical tweezers in single-molecule biophysics. | Bustamante CJ, Chemla YR, Liu S, Wang MD | Nature reviews. Methods primers | 34849486 | Nat Rev Methods Primers | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34849486 |
The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates. | Mickolajczyk KJ, Olinares PDB, Chait BT, Liu S, Kapoor TM | eLife | 35147499 | Elife | 2022 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/35147499 |
Nucleosome-directed replication origin licensing independent of a consensus DNA sequence. | Li S, Wasserman MR, Yurieva O, Bai L, O'Donnell ME, Liu S | Nature communications | 35999198 | Nat Commun | 2022 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/35999198 |
Molecular mechanism for direct actin force-sensing by α-catenin. | Mei L, Espinosa de Los Reyes S, Reynolds MJ, Leicher R, Liu S, Alushin GM | eLife | 32969337 | Elife | 2020 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/32969337 |
Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses. | Wang L, Johnson ZL, Wasserman MR, Levring J, Chen J, Liu S | eLife | 32458799 | Elife | 2020 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/32458799 |
Probing the Interaction Between Chromatin and Chromatin-Associated Complexes with Optical Tweezers. | Leicher R, Liu S | Methods in molecular biology (Clifton, N.J.) | 36063325 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36063325 |
Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA. | Nguyen T, Li S, Chang JT, Watters JW, Ng H, Osunsade A, David Y, Liu S | Nature communications | 35810158 | Nat Commun | 2022 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/35810158 |
Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA. | Chua GNL, Watters JW, Olinares PDB, Begum M, Vostal LE, Luo JA, Chait BT, Liu S | Nature structural & molecular biology | 39164525 | Nat Struct Mol Biol | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39164525 |
Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase. | Wasserman MR, Schauer GD, O'Donnell ME, Liu S | Cell | 31348887 | Cell | 2019 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/31348887 |
A Tour de Force on the Double Helix: Exploiting DNA Mechanics To Study DNA-Based Molecular Machines. | Wasserman MR, Liu S | Biochemistry | 31251042 | Biochemistry | 2019 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/31251042 |
Full-length RNA profiling reveals pervasive bidirectional transcription terminators in bacteria. | Ju X, Li D, Liu S | Nature microbiology | 31308523 | Nat Microbiol | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31308523 |
Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase. | Mickolajczyk KJ, Shelton PMM, Grasso M, Cao X, Warrington SE, Aher A, Liu S, Kapoor TM | Biophysical journal | 33340543 | Biophys J | 2021 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/33340543 |
Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin. | Leicher R, Ge EJ, Lin X, Reynolds MJ, Xie W, Walz T, Zhang B, Muir TW, Liu S | Proceedings of the National Academy of Sciences of the United States of America | 33208532 | Proc Natl Acad Sci U S A | 2020 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/33208532 |
Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome. | Ju X, Li S, Froom R, Wang L, Lilic M, Delbeau M, Campbell EA, Rock JM, Liu S | Nature | 38418874 | Nature | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38418874 |
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. | Abini-Agbomson S, Gretarsson K, Shih RM, Hsieh L, Lou T, De Ioannes P, Vasilyev N, Lee R, Wang M, Simon MD, Armache JP, Nudler E, Narlikar G, Liu S, Lu C, Armache KJ | Molecular cell | 37595555 | Mol Cell | 2023 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/37595555 |
Tracking cell lineages to improve research reproducibility. | Zaaijer S, Groen SC, Sanjana NE | Nature biotechnology | 34012093 | Nat Biotechnol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34012093 |
Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens. | Liscovitch-Brauer N, Montalbano A, Deng J, Méndez-Mancilla A, Wessels HH, Moss NG, Kung CY, Sookdeo A, Guo X, Geller E, Jaini S, Smibert P, Sanjana NE | Nature biotechnology | 33927415 | Nat Biotechnol | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33927415 |
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells. | Daniloski Z, Jordan TX, Wessels HH, Hoagland DA, Kasela S, Legut M, Maniatis S, Mimitou EP, Lu L, Geller E, Danziger O, Rosenberg BR, Phatnani H, Smibert P, Lappalainen T, tenOever BR, Sanjana NE | Cell | 33147445 | Cell | 2021 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/33147445 |
Essential transcription factors for induced neuron differentiation. | Lu C, Garipler G, Dai C, Roush T, Salome-Correa J, Martin A, Liscovitch-Brauer N, Mazzoni EO, Sanjana NE | Nature communications | 38102126 | Nat Commun | 2023 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/38102126 |
Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling. | Yan RE, Corman A, Katgara L, Wang X, Xue X, Gajic ZZ, Sam R, Farid M, Friedman SM, Choo J, Raimondi I, Ganesan S, Katsevich E, Greenfield JP, Dahmane N, Sanjana NE | Nature biotechnology | 39572737 | Nat Biotechnol | 2024 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/39572737 |
Prediction of on-target and off-target activity of CRISPR-Cas13d guide RNAs using deep learning. | Wessels HH, Stirn A, Méndez-Mancilla A, Kim EJ, Hart SK, Knowles DA, Sanjana NE | Nature biotechnology | 37400521 | Nat Biotechnol | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37400521 |
Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy. | Lek A, Zhang Y, Woodman KG, Huang S, DeSimone AM, Cohen J, Ho V, Conner J, Mead L, Kodani A, Pakula A, Sanjana N, King OD, Jones PL, Wagner KR, Lek M, Kunkel LM | Science translational medicine | 32213627 | Sci Transl Med | 2020 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/32213627 |
Generation of a knock-in MAP2-tdTomato reporter human embryonic stem cell line with inducible expression of NEUROG2/1 (NYGCe001-A). | Lu C, Sanjana NE | Stem cell research | 31707212 | Stem Cell Res | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31707212 |
Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus. | Kasela S, Daniloski Z, Bollepalli S, Jordan TX, tenOever BR, Sanjana NE, Lappalainen T | Genome biology | 34425859 | Genome Biol | 2021 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/34425859 |
GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease. | Li L, Tian E, Chen X, Chao J, Klein J, Qu Q, Sun G, Sun G, Huang Y, Warden CD, Ye P, Feng L, Li X, Cui Q, Sultan A, Douvaras P, Fossati V, Sanjana NE, Riggs AD, Shi Y | Cell stem cell | 30075130 | Cell Stem Cell | 2018 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/30075130 |
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes. | Garipler G, Lu C, Morrissey A, Lopez-Zepeda LS, Pei Y, Vidal SE, Zen Petisco Fiore AP, Aydin B, Stadtfeld M, Ohler U, Mahony S, Sanjana NE, Mazzoni EO | Cell reports | 35294876 | Cell Rep | 2022 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/35294876 |
Cancer genes disfavoring T cell immunity identified via integrated systems approach. | Kishton RJ, Patel SJ, Decker AE, Vodnala SK, Cam M, Yamamoto TN, Patel Y, Sukumar M, Yu Z, Ji M, Henning AN, Gurusamy D, Palmer DC, Stefanescu RA, Girvin AT, Lo W, Pasetto A, Malekzadeh P, Deniger DC, Wood KC, Sanjana NE, Restifo NP | Cell reports | 35926468 | Cell Rep | 2022 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/35926468 |
Comprehensive dissection of cis-regulatory elements in a 2.8 Mb topologically associated domain in six human cancers. | Caragine CM, Le VT, Mustafa M, Diaz BJ, Morris JA, Müller S, Mendez-Mancilla A, Geller E, Liscovitch-Brauer N, Sanjana NE | Nature communications | 39948336 | Nat Commun | 2025 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/39948336 |
Massively parallel Cas13 screens reveal principles for guide RNA design. | Wessels HH, Méndez-Mancilla A, Guo X, Legut M, Daniloski Z, Sanjana NE | Nature biotechnology | 32518401 | Nat Biotechnol | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32518401 |
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types. | Daniloski Z, Jordan TX, Ilmain JK, Guo X, Bhabha G, tenOever BR, Sanjana NE | eLife | 33570490 | Elife | 2021 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/33570490 |
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome. | Montalbano A, Canver MC, Sanjana NE | Molecular cell | 28985510 | Mol Cell | 2017 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/28985510 |
Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells. | Mimitou EP, Cheng A, Montalbano A, Hao S, Stoeckius M, Legut M, Roush T, Herrera A, Papalexi E, Ouyang Z, Satija R, Sanjana NE, Koralov SB, Smibert P | Nature methods | 31011186 | Nat Methods | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/31011186 |
Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes. | Liu EM, Martinez-Fundichely A, Diaz BJ, Aronson B, Cuykendall T, MacKay M, Dhingra P, Wong EWP, Chi P, Apostolou E, Sanjana NE, Khurana E | Cell systems | 31078526 | Cell Syst | 2019 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/31078526 |
High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation. | Legut M, Daniloski Z, Xue X, McKenzie D, Guo X, Wessels HH, Sanjana NE | Cell reports | 32130891 | Cell Rep | 2020 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/32130891 |
A genome-wide net to catch and understand cancer. | Sanjana NE | Science translational medicine | 30089637 | Sci Transl Med | 2018 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/30089637 |
Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells. | Méndez-Mancilla A, Wessels HH, Legut M, Kadina A, Mabuchi M, Walker J, Robb GB, Holden K, Sanjana NE | Cell chemical biology | 34343484 | Cell Chem Biol | 2022 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/34343484 |
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. | Wei W, Geer MJ, Guo X, Dolgalev I, Sanjana NE, Neel BG | The Journal of experimental medicine | 36820830 | J Exp Med | 2023 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/36820830 |
Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq. | Wessels HH, Méndez-Mancilla A, Hao Y, Papalexi E, Mauck WM 3rd, Lu L, Morris JA, Mimitou EP, Smibert P, Sanjana NE, Satija R | Nature methods | 36550277 | Nat Methods | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36550277 |
Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction. | Shi X, Lu C, Corman A, Nikish A, Zhou Y, Platt RJ, Iossifov I, Zhang F, Pan JQ, Sanjana NE | American journal of human genetics | 37802044 | Am J Hum Genet | 2023 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/37802044 |
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens. | Morris JA, Caragine C, Daniloski Z, Domingo J, Barry T, Lu L, Davis K, Ziosi M, Glinos DA, Hao S, Mimitou EP, Smibert P, Roeder K, Katsevich E, Lappalainen T, Sanjana NE | Science (New York, N.Y.) | 37141313 | Science | 2023 May 19 | https://www.ncbi.nlm.nih.gov/pubmed/37141313 |
Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells. | Liang WW, Müller S, Hart SK, Wessels HH, Méndez-Mancilla A, Sookdeo A, Choi O, Caragine CM, Corman A, Lu L, Kolumba O, Williams B, Sanjana NE | Cell | 39532094 | Cell | 2024 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/39532094 |
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types. | Daniloski Z, Jordan TX, Ilmain JK, Guo X, Bhabha G, tenOever BR, Sanjana NE | bioRxiv : the preprint server for biology | 32587969 | bioRxiv | 2020 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/32587969 |
Expanding the Scope of Bacterial CRISPR Activation with PAM-Flexible dCas9 Variants. | Kiattisewee C, Karanjia AV, Legut M, Daniloski Z, Koplik SE, Nelson J, Kleinstiver BP, Sanjana NE, Carothers JM, Zalatan JG | ACS synthetic biology | 36378874 | ACS Synth Biol | 2022 Dec 16 | https://www.ncbi.nlm.nih.gov/pubmed/36378874 |
A genome-scale screen for synthetic drivers of T cell proliferation. | Legut M, Gajic Z, Guarino M, Daniloski Z, Rahman JA, Xue X, Lu C, Lu L, Mimitou EP, Hao S, Davoli T, Diefenbach C, Smibert P, Sanjana NE | Nature | 35296855 | Nature | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35296855 |
Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens. | Guo X, Rahman JA, Wessels HH, Méndez-Mancilla A, Haro D, Chen X, Sanjana NE | Cell genomics | 35664829 | Cell Genom | 2021 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/35664829 |
Recurrent somatic mutations as predictors of immunotherapy response. | Gajic ZZ, Deshpande A, Legut M, Imieliński M, Sanjana NE | Nature communications | 35803911 | Nat Commun | 2022 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/35803911 |
Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus. | Kasela S, Daniloski Z, Jordan TX, tenOever BR, Sanjana NE, Lappalainen T | medRxiv : the preprint server for health sciences | 33880488 | medRxiv | 2021 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/33880488 |
Overexpression of NEUROG2 and NEUROG1 in human embryonic stem cells produces a network of excitatory and inhibitory neurons. | Lu C, Shi X, Allen A, Baez-Nieto D, Nikish A, Sanjana NE, Pan JQ | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 30698461 | FASEB J | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30698461 |
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. | Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H | Proceedings of the National Academy of Sciences of the United States of America | 38743625 | Proc Natl Acad Sci U S A | 2024 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/38743625 |
Next-generation forward genetic screens: uniting high-throughput perturbations with single-cell analysis. | Morris JA, Sun JS, Sanjana NE | Trends in genetics : TIG | 37989654 | Trends Genet | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/37989654 |
Non-linear transcriptional responses to gradual modulation of transcription factor dosage. | Domingo J, Minaeva M, Morris JA, Ghatan S, Ziosi M, Sanjana NE, Lappalainen T | bioRxiv : the preprint server for biology | 38464330 | bioRxiv | 2024 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/38464330 |
Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox. | Schertzer MD, Stirn A, Isaev K, Pereira L, Das A, Harbison C, Park SH, Wessels HH, Sanjana NE, Knowles DA | bioRxiv : the preprint server for biology | 37745416 | bioRxiv | 2023 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/37745416 |
Precise RNA targeting with CRISPR-Cas13d. | Hart SK, Müller S, Wessels HH, Méndez-Mancilla A, Drabavicius G, Choi O, Sanjana NE | Nature biotechnology | 39934271 | Nat Biotechnol | 2025 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/39934271 |
3D genomics across the tree of life reveals condensin II as a determinant of architecture type. | Hoencamp C, Dudchenko O, Elbatsh AMO, Brahmachari S, Raaijmakers JA, van Schaik T, Sedeño Cacciatore Á, Contessoto VG, van Heesbeen RGHP, van den Broek B, Mhaskar AN, Teunissen H, St Hilaire BG, Weisz D, Omer AD, Pham M, Colaric Z, Yang Z, Rao SSP, Mitra N, Lui C, Yao W, Khan R, Moroz LL, Kohn A, St Leger J, Mena A, Holcroft K, Gambetta MC, Lim F, Farley E, Stein N, Haddad A, Chauss D, Mutlu AS, Wang MC, Young ND, Hildebrandt E, Cheng HH, Knight CJ, Burnham TLU, Hovel KA, Beel AJ, Mattei PJ, Kornberg RD, Warren WC, Cary G, Gómez-Skarmeta JL, Hinman V, Lindblad-Toh K, Di Palma F, Maeshima K, Multani AS, Pathak S, Nel-Themaat L, Behringer RR, Kaur P, Medema RH, van Steensel B, de Wit E, Onuchic JN, Di Pierro M, Lieberman Aiden E, Rowland BD | Science (New York, N.Y.) | 34045355 | Science | 2021 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/34045355 |
Predictive analyses of regulatory sequences with EUGENe. | Klie A, Laub D, Talwar JV, Stites H, Jores T, Solvason JJ, Farley EK, Carter H | Nature computational science | 38177592 | Nat Comput Sci | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/38177592 |
Conserved enhancers control notochord expression of vertebrate Brachyury. | Kemmler CL, Smolikova J, Moran HR, Mannion BJ, Knapp D, Lim F, Czarkwiani A, Hermosilla Aguayo V, Rapp V, Fitch OE, Bötschi S, Selleri L, Farley E, Braasch I, Yun M, Visel A, Osterwalder M, Mosimann C, Kozmik Z, Burger A | Nature communications | 37852970 | Nat Commun | 2023 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/37852970 |
Single-nucleotide variants within heart enhancers increase binding affinity and disrupt heart development. | Jindal GA, Bantle AT, Solvason JJ, Grudzien JL, D'Antonio-Chronowska A, Lim F, Le SH, Song BP, Ragsac MF, Klie A, Larsen RO, Frazer KA, Farley EK | Developmental cell | 37848026 | Dev Cell | 2023 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/37848026 |
Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer. | D Antonio M, Weghorn D, D Antonio-Chronowska A, Coulet F, Olson KM, DeBoever C, Drees F, Arias A, Alakus H, Richardson AL, Schwab RB, Farley EK, Sunyaev SR, Frazer KA | Nature communications | 28874753 | Nat Commun | 2017 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/28874753 |
Affinity-optimizing enhancer variants disrupt development. | Lim F, Solvason JJ, Ryan GE, Le SH, Jindal GA, Steffen P, Jandu SK, Farley EK | Nature | 38233525 | Nature | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38233525 |
Conserved enhancer logic controls the notochord expression of vertebrate Brachyury. | Kemmler CL, Smolikova J, Moran HR, Mannion BJ, Knapp D, Lim F, Czarkwiani A, Hermosilla Aguayo V, Rapp V, Fitch OE, Bötschi S, Selleri L, Farley E, Braasch I, Yun M, Visel A, Osterwalder M, Mosimann C, Kozmik Z, Burger A | bioRxiv : the preprint server for biology | 37131681 | bioRxiv | 2023 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/37131681 |
Functional genomic approaches to elucidate the role of enhancers during development. | Ryan GE, Farley EK | Wiley interdisciplinary reviews. Systems biology and medicine | 31808313 | Wiley Interdiscip Rev Syst Biol Med | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31808313 |
Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells. | DeBoever C, Li H, Jakubosky D, Benaglio P, Reyna J, Olson KM, Huang H, Biggs W, Sandoval E, D'Antonio M, Jepsen K, Matsui H, Arias A, Ren B, Nariai N, Smith EN, D'Antonio-Chronowska A, Farley EK, Frazer KA | Cell stem cell | 28388430 | Cell Stem Cell | 2017 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/28388430 |
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression. | Zhang W, Bojorquez-Gomez A, Velez DO, Xu G, Sanchez KS, Shen JP, Chen K, Licon K, Melton C, Olson KM, Yu MK, Huang JK, Carter H, Farley EK, Snyder M, Fraley SI, Kreisberg JF, Ideker T | Nature genetics | 29610481 | Nat Genet | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29610481 |
Diverse logics and grammar encode notochord enhancers. | Song BP, Ragsac MF, Tellez K, Jindal GA, Grudzien JL, Le SH, Farley EK | Cell reports | 36729834 | Cell Rep | 2023 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/36729834 |
Enhancer grammar in development, evolution, and disease: dependencies and interplay. | Jindal GA, Farley EK | Developmental cell | 33689769 | Dev Cell | 2021 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/33689769 |
Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. | Villani AC, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, Griesbeck M, Butler A, Zheng S, Lazo S, Jardine L, Dixon D, Stephenson E, Nilsson E, Grundberg I, McDonald D, Filby A, Li W, De Jager PL, Rozenblatt-Rosen O, Lane AA, Haniffa M, Regev A, Hacohen N | Science (New York, N.Y.) | 28428369 | Science | 2017 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/28428369 |
Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation. | Stephenson W, Donlin LT, Butler A, Rozo C, Bracken B, Rashidfarrokhi A, Goodman SM, Ivashkiv LB, Bykerk VP, Orange DE, Darnell RB, Swerdlow HP, Satija R | Nature communications | 29476078 | Nat Commun | 2018 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/29476078 |
Comprehensive Integration of Single-Cell Data. | Stuart T, Butler A, Hoffman P, Hafemeister C, Papalexi E, Mauck WM 3rd, Hao Y, Stoeckius M, Smibert P, Satija R | Cell | 31178118 | Cell | 2019 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/31178118 |
Phospho-seq: integrated, multi-modal profiling of intracellular protein dynamics in single cells. | Blair JD, Hartman A, Zenk F, Wahle P, Brancati G, Dalgarno C, Treutlein B, Satija R | Nature communications | 39905064 | Nat Commun | 2025 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/39905064 |
Human dendritic cells (DCs) are derived from distinct circulating precursors that are precommitted to become CD1c+ or CD141+ DCs. | Breton G, Zheng S, Valieris R, Tojal da Silva I, Satija R, Nussenzweig MC | The Journal of experimental medicine | 27864467 | J Exp Med | 2016 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/27864467 |
Characterizing the molecular regulation of inhibitory immune checkpoints with multimodal single-cell screens. | Papalexi E, Mimitou EP, Butler AW, Foster S, Bracken B, Mauck WM 3rd, Wessels HH, Hao Y, Yeung BZ, Smibert P, Satija R | Nature genetics | 33649593 | Nat Genet | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33649593 |
Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics. | Stoeckius M, Zheng S, Houck-Loomis B, Hao S, Yeung BZ, Mauck WM 3rd, Smibert P, Satija R | Genome biology | 30567574 | Genome Biol | 2018 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/30567574 |
Simultaneous epitope and transcriptome measurement in single cells. | Stoeckius M, Hafemeister C, Stephenson W, Houck-Loomis B, Chattopadhyay PK, Swerdlow H, Satija R, Smibert P | Nature methods | 28759029 | Nat Methods | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28759029 |
Dictionary learning for integrative, multimodal and scalable single-cell analysis. | Hao Y, Stuart T, Kowalski MH, Choudhary S, Hoffman P, Hartman A, Srivastava A, Molla G, Madad S, Fernandez-Granda C, Satija R | Nature biotechnology | 37231261 | Nat Biotechnol | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/37231261 |
Phenotypic Convergence: Distinct Transcription Factors Regulate Common Terminal Features. | Konstantinides N, Kapuralin K, Fadil C, Barboza L, Satija R, Desplan C | Cell | 29909983 | Cell | 2018 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/29909983 |
Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression. | Hafemeister C, Satija R | Genome biology | 31870423 | Genome Biol | 2019 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/31870423 |
Developmental diversification of cortical inhibitory interneurons. | Mayer C, Hafemeister C, Bandler RC, Machold R, Batista Brito R, Jaglin X, Allaway K, Butler A, Fishell G, Satija R | Nature | 29513653 | Nature | 2018 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/29513653 |
A single-cell transcriptional roadmap for cardiopharyngeal fate diversification. | Wang W, Niu X, Stuart T, Jullian E, Mauck WM 3rd, Kelly RG, Satija R, Christiaen L | Nature cell biology | 31160712 | Nat Cell Biol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31160712 |
Toward a Common Coordinate Framework for the Human Body. | Rood JE, Stuart T, Ghazanfar S, Biancalani T, Fisher E, Butler A, Hupalowska A, Gaffney L, Mauck W, Eraslan G, Marioni JC, Regev A, Satija R | Cell | 31835027 | Cell | 2019 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/31835027 |
Single-cell chromatin state analysis with Signac. | Stuart T, Srivastava A, Madad S, Lareau CA, Satija R | Nature methods | 34725479 | Nat Methods | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34725479 |
Comparison and evaluation of statistical error models for scRNA-seq. | Choudhary S, Satija R | Genome biology | 35042561 | Genome Biol | 2022 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/35042561 |
A Reproducibility Focused Meta-Analysis Method for Single-Cell Transcriptomic Case-Control Studies Uncovers Robust Differentially Expressed Genes. | Nakatsuka N, Adler D, Jiang L, Hartman A, Cheng E, Klann E, Satija R | bioRxiv : the preprint server for biology | 39463993 | bioRxiv | 2025 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/39463993 |
A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells. | Velasco S, Ibrahim MM, Kakumanu A, Garipler G, Aydin B, Al-Sayegh MA, Hirsekorn A, Abdul-Rahman F, Satija R, Ohler U, Mahony S, Mazzoni EO | Cell stem cell | 27939218 | Cell Stem Cell | 2017 Feb 2 | https://www.ncbi.nlm.nih.gov/pubmed/27939218 |
Single cell transcriptomics in human osteoarthritis synovium and in silico deconvoluted bulk RNA sequencing. | Huang ZY, Luo ZY, Cai YR, Chou CH, Yao ML, Pei FX, Kraus VB, Zhou ZK | Osteoarthritis and cartilage | 34971754 | Osteoarthritis Cartilage | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/34971754 |
Characterizing cellular heterogeneity in chromatin state with scCUT&Tag-pro. | Zhang B, Srivastava A, Mimitou E, Stuart T, Raimondi I, Hao Y, Smibert P, Satija R | Nature biotechnology | 35332340 | Nat Biotechnol | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35332340 |
Integrated analysis of multimodal single-cell data. | Hao Y, Hao S, Andersen-Nissen E, Mauck WM 3rd, Zheng S, Butler A, Lee MJ, Wilk AJ, Darby C, Zager M, Hoffman P, Stoeckius M, Papalexi E, Mimitou EP, Jain J, Srivastava A, Stuart T, Fleming LM, Yeung B, Rogers AJ, McElrath JM, Blish CA, Gottardo R, Smibert P, Satija R | Cell | 34062119 | Cell | 2021 Jun 24 | https://www.ncbi.nlm.nih.gov/pubmed/34062119 |
The bone marrow microenvironment at single-cell resolution. | Tikhonova AN, Dolgalev I, Hu H, Sivaraj KK, Hoxha E, Cuesta-Domínguez Á, Pinho S, Akhmetzyanova I, Gao J, Witkowski M, Guillamot M, Gutkin MC, Zhang Y, Marier C, Diefenbach C, Kousteni S, Heguy A, Zhong H, Fooksman DR, Butler JM, Economides A, Frenette PS, Adams RH, Satija R, Tsirigos A, Aifantis I | Nature | 30971824 | Nature | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30971824 |
Integrating single-cell transcriptomic data across different conditions, technologies, and species. | Butler A, Hoffman P, Smibert P, Papalexi E, Satija R | Nature biotechnology | 29608179 | Nat Biotechnol | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29608179 |
Navigating human embryogenesis through tailored model selection. | Sozen B | Nature cell biology | 39528699 | Nat Cell Biol | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39528699 |
A brief history of metabolic gradient theory. | Sozen B | Nature reviews. Genetics | 39414955 | Nat Rev Genet | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39414955 |
Selective utilization of glucose metabolism guides mammalian gastrulation. | Cao D, Bergmann J, Zhong L, Hemalatha A, Dingare C, Jensen T, Cox AL, Greco V, Steventon B, Sozen B | Nature | 39415005 | Nature | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39415005 |
Shifting early embryology paradigms: Applications of stem cell-based embryo models in bioengineering. | Abel A, Sozen B | Current opinion in genetics & development | 37392541 | Curr Opin Genet Dev | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37392541 |
A Spatiotemporal Compartmentalization of Glucose Metabolism Guides Mammalian Gastrulation Progression. | Cao D, Zhong L, Hemalatha A, Bergmann J, Cox AL, Greco V, Sozen B | bioRxiv : the preprint server for biology | 37333168 | bioRxiv | 2023 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/37333168 |
A Review of Current State-of-the-Art Control Methods for Lower-Limb Powered Prostheses. | Gehlhar R, Tucker M, Young AJ, Ames AD | Annual reviews in control | 37635763 | Annu Rev Control | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37635763 |
Dynamic Duo: Design and Validation of an Autonomous Frontal and Sagittal Actuating Hip Exoskeleton for Balance Modulation During Perturbed Locomotion. | Leestma JK, Mathur S, Anderton MD, Sawicki GS, Young AJ | IEEE robotics and automation letters | 40012859 | IEEE Robot Autom Lett | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/40012859 |
A Deep Learning Framework for End-to-End Control of Powered Prostheses. | Nuesslein CPO, Young AJ | IEEE robotics and automation letters | 40012860 | IEEE Robot Autom Lett | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/40012860 |
Improving Biological Joint Moment Estimation During Real-World Tasks With EMG and Instrumented Insoles. | Scherpereel KL, Molinaro DD, Shepherd MK, Inan OT, Young AJ | IEEE transactions on bio-medical engineering | 38619965 | IEEE Trans Biomed Eng | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/38619965 |
A Data-Driven Approach to Estimate Human Center of Mass State During Perturbed Locomotion Using Simulated Wearable Sensors. | Leestma JK, Smith CR, Sawicki GS, Young AJ | Annals of biomedical engineering | 38558352 | Ann Biomed Eng | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38558352 |
Mode-Unified Intent Estimation of a Robotic Prosthesis using Deep-Learning. | Kim H, Lee D, Maldonado-Contreras JY, Zhou S, Herrin KR, Young AJ | IEEE robotics and automation letters | 40124848 | IEEE Robot Autom Lett | 2025 Apr | https://www.ncbi.nlm.nih.gov/pubmed/40124848 |
Emerging frontiers in regenerative medicine. | McKinley KL, Longaker MT, Naik S | Science (New York, N.Y.) | 37228215 | Science | 2023 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/37228215 |
Mechanisms of Regeneration and Fibrosis in the Endometrium. | Ang CJ, Skokan TD, McKinley KL | Annual review of cell and developmental biology | 37843929 | Annu Rev Cell Dev Biol | 2023 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/37843929 |
Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids. | Bolondi A, Law BK, Kretzmer H, Gassaloglu SI, Buschow R, Riemenschneider C, Yang D, Walther M, Veenvliet JV, Meissner A, Smith ZD, Chan MM | Developmental cell | 38579718 | Dev Cell | 2024 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/38579718 |
Inferring cell differentiation maps from lineage tracing data. | Sashittal P, Zhang RY, Law BK, Strzalkowski A, Schmidt H, Bolondi A, Chan MM, Raphael BJ | bioRxiv : the preprint server for biology | 39314473 | bioRxiv | 2024 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/39314473 |
Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis. | Li X, Gordon PJ, Gaynes JA, Fuller AW, Ringuette R, Santiago CP, Wallace V, Blackshaw S, Li P, Levine EM | eLife | 36459481 | Elife | 2022 Dec 2 | https://www.ncbi.nlm.nih.gov/pubmed/36459481 |
Diffusion barriers imposed by tissue topology shape Hedgehog morphogen gradients. | Schlissel G, Meziane M, Narducci D, Hansen AS, Li P | Proceedings of the National Academy of Sciences of the United States of America | 39190357 | Proc Natl Acad Sci U S A | 2024 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/39190357 |
A fine kinetic balance of interactions directs transcription factor hubs to genes. | Fallacaro S, Mukherjee A, Ratchasanmuang P, Zinski J, Haloush YI, Shankta K, Mir M | bioRxiv : the preprint server for biology | 38659757 | bioRxiv | 2024 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/38659757 |
Dynamic microenvironments shape nuclear organization and gene expression. | Hayward-Lara G, Fischer MD, Mir M | Current opinion in genetics & development | 38461773 | Curr Opin Genet Dev | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38461773 |
Localization of the Drosophila pioneer factor GAF to subnuclear foci is driven by DNA binding and required to silence satellite repeat expression. | Gaskill MM, Soluri IV, Branks AE, Boka AP, Stadler MR, Vietor K, Huang HS, Gibson TJ, Mukherjee A, Mir M, Blythe SA, Harrison MM | Developmental cell | 37478844 | Dev Cell | 2023 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/37478844 |
A cluster of RNA Polymerase II molecules is stably associated with an active gene. | Mukherjee A, Kapoor M, Shankta K, Fallacaro S, Carter RD, Ratchasanmuang P, Haloush YI, Mir M | bioRxiv : the preprint server for biology | 39990393 | bioRxiv | 2025 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/39990393 |
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres. | Malla AB, Yu H, Farris D, Kadimi S, Lam TT, Cox AL, Smith ZD, Lesch BJ | EMBO reports | 37317657 | EMBO Rep | 2023 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/37317657 |
Autonomous transposons tune their sequences to ensure somatic suppression. | Ilık İA, Glažar P, Tse K, Brändl B, Meierhofer D, Müller FJ, Smith ZD, Aktaş T | Nature | 38355802 | Nature | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38355802 |
DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement. | Malla AB, Rainsford SR, Smith ZD, Lesch BJ | Development (Cambridge, England) | 37082969 | Development | 2023 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/37082969 |
DNA methylation in mammalian development and disease. | Smith ZD, Hetzel S, Meissner A | Nature reviews. Genetics | 39134824 | Nat Rev Genet | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39134824 |
Dynamic antagonism between key repressive pathways maintains the placental epigenome. | Weigert R, Hetzel S, Bailly N, Haggerty C, Ilik IA, Yung PYK, Navarro C, Bolondi A, Kumar AS, Anania C, Brändl B, Meierhofer D, Lupiáñez DG, Müller FJ, Aktas T, Elsässer SJ, Kretzmer H, Smith ZD, Meissner A | Nature cell biology | 37024684 | Nat Cell Biol | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37024684 |
Neurophysin I is an analytically robust surrogate biomarker for oxytocin. | MacLean EL, Carranza E, Gnanadesikan GE, King KM, Allen AM, Linde-Krieger LB, Feldman R, White-Traut RC, Hammock EAD, Carter CS, Leng G, Tecot SR, Bell AF | Psychoneuroendocrinology | 38194845 | Psychoneuroendocrinology | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38194845 |
Opportunities to expand postpartum support for those in recovery from opioid use disorder: Results from a qualitative study. | Allen A, Bueno Y, Mallahan S, MacPherson AH, Armin J | Drug and alcohol dependence reports | 37334156 | Drug Alcohol Depend Rep | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37334156 |
Babywearing Reduces Urges to Use Substances in the Postpartum Period Among Mothers With OUDs. | Rankin L, Grisham LM, Mendoza N, Allen A | Substance use & misuse | 38404001 | Subst Use Misuse | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38404001 |
A qualitative exploration of the eight dimensions of wellness in opioid use disorder recovery during the postpartum period. | Mallahan S, Armin J, Bueno Y, Huff A, Allen A | Drug and alcohol dependence reports | 37131999 | Drug Alcohol Depend Rep | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37131999 |
Post-transcriptional tuning of FGF signaling mediates neural crest induction. | Copeland J, Simoes-Costa M | Proceedings of the National Academy of Sciences of the United States of America | 33376218 | Proc Natl Acad Sci U S A | 2020 Dec 29 | https://www.ncbi.nlm.nih.gov/pubmed/33376218 |
Aggressive but not reproductive boldness in male green anole lizards correlates with baseline vasopressin activity. | Kabelik D, Julien AR, Waddell BR, Batschelett MA, O'Connell LA | Hormones and behavior | 35066329 | Horm Behav | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35066329 |
Frank Beach Award Winner: Lessons from poison frogs on ecological drivers of behavioral diversification. | O'Connell LA | Hormones and behavior | 33039350 | Horm Behav | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33039350 |
The Parental Dilemma: How Evolution of Diverse Strategies for Infant Care Informs Social Behavior Circuits. | Autry AE, O'Connell LA | Frontiers in neural circuits | 34867211 | Front Neural Circuits | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34867211 |
Activity of FoxP2-positive neurons is associated with tadpole begging behavior. | Ludington SC, McKinney JE, Butler JM, Goolsby BC, Callan AA, Gaines-Richardson M, O'Connell LA | bioRxiv : the preprint server for biology | 37292748 | bioRxiv | 2024 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/37292748 |
Home security cameras as a tool for behavior observations and science affordability. | Goolsby BC, Fischer MT, Chen TG, Pareja-Mejía D, Shaykevich DA, Lewis AR, Raboisson G, Lacey MP, O'Connell LA | bioRxiv : the preprint server for biology | 37131676 | bioRxiv | 2024 Apr 22 | https://www.ncbi.nlm.nih.gov/pubmed/37131676 |
Effects of parental care on skin microbial community composition in poison frogs. | Fischer MT, Xue KS, Costello EK, Dvorak M, Raboisson G, Robaczewska A, Caty SN, Relman DA, O'Connell LA | bioRxiv : the preprint server for biology | 39314287 | bioRxiv | 2024 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/39314287 |
Social boldness correlates with brain gene expression in male green anoles. | Kabelik D, Julien AR, Ramirez D, O'Connell LA | Hormones and behavior | 34102460 | Horm Behav | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34102460 |
A toxic environment selects for specialist microbiome in poison frogs. | Caty SN, Alvarez-Buylla A, Vasek C, Tapia EE, Martin NA, McLaughlin T, Weber PK, Mayali X, Coloma LA, Morris MM, O'Connell LA | bioRxiv : the preprint server for biology | 38260330 | bioRxiv | 2024 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/38260330 |
Physiological state matching in a pair bonded poison frog. | Nowicki JP, Rodríguez C, Lee JC, Goolsby BC, Yang C, Cleland TA, O'Connell LA | Royal Society open science | 39076367 | R Soc Open Sci | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/39076367 |
Evolutionary insights into sexual behavior from whiptail lizards. | O'Connell LA, Crews D | Journal of experimental zoology. Part A, Ecological and integrative physiology | 33929097 | J Exp Zool A Ecol Integr Physiol | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33929097 |
Studying convergent evolution to relate genotype to behavioral phenotype. | Gallant JR, O'Connell LA | The Journal of experimental biology | 32034050 | J Exp Biol | 2020 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/32034050 |
Infanticide is driven by unfamiliarity with offspring location and associated with androgenic shifts in mimic poison frogs. | Lewis AR, Goolsby BC, Juarez BH, Lacey MP, O'Connell LA | bioRxiv : the preprint server for biology | 39484385 | bioRxiv | 2024 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/39484385 |
Infanticide is driven by unfamiliarity with offspring location and associated with androgenic shifts in mimic poison frogs. | Lewis AR, Goolsby BC, Juarez BH, Lacey MP, O'Connell LA | Hormones and behavior | 39514924 | Horm Behav | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39514924 |
Adherent-invasive E. coli metabolism of propanediol in Crohn's disease regulates phagocytes to drive intestinal inflammation. | Viladomiu M, Metz ML, Lima SF, Jin WB, Chou L, JRI Live Cell Bank, Guo CJ, Diehl GE, Simpson KW, Scherl EJ, Longman RS | Cell host & microbe | 33539767 | Cell Host Microbe | 2021 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/33539767 |
Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome. | Jin WB, Li TT, Huo D, Qu S, Li XV, Arifuzzaman M, Lima SF, Shi HQ, Wang A, Putzel GG, Longman RS, Artis D, Guo CJ | Cell | 35051369 | Cell | 2022 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/35051369 |
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression. | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J | Nature communications | 36266345 | Nat Commun | 2022 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/36266345 |
Nutritional regulation of microbiota-derived metabolites: Implications for immunity and inflammation. | Arifuzzaman M, Collins N, Guo CJ, Artis D | Immunity | 38198849 | Immunity | 2024 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/38198849 |
Functional characterization of helminth-associated Clostridiales reveals covariates of Treg differentiation. | Sargsian S, Lejeune A, Ercelen D, Jin WB, Varghese A, Loke P, Lim YAL, Guo CJ, Cadwell K | bioRxiv : the preprint server for biology | 37333296 | bioRxiv | 2023 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/37333296 |
Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation. | Arifuzzaman M, Won TH, Li TT, Yano H, Digumarthi S, Heras AF, Zhang W, Parkhurst CN, Kashyap S, Jin WB, Putzel GG, Tsou AM, Chu C, Wei Q, Grier A, JRI IBD Live Cell Bank Consortium, Worgall S, Guo CJ, Schroeder FC, Artis D | Nature | 36323778 | Nature | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/36323778 |
Host metabolism balances microbial regulation of bile acid signalling. | Won TH, Arifuzzaman M, Parkhurst CN, Miranda IC, Zhang B, Hu E, Kashyap S, Letourneau J, Jin WB, Fu Y, Guzior DV, JRI Live Cell Bank, Quinn RA, Guo CJ, David LA, Artis D, Schroeder FC | Nature | 39779854 | Nature | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39779854 |
A metabolic pathway for bile acid dehydroxylation by the gut microbiome. | Funabashi M, Grove TL, Wang M, Varma Y, McFadden ME, Brown LC, Guo C, Higginbottom S, Almo SC, Fischbach MA | Nature | 32555455 | Nature | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32555455 |
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. | Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY | Nature | 32461639 | Nature | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32461639 |
Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection. | Zhang W, Lyu M, Bessman NJ, Xie Z, Arifuzzaman M, Yano H, Parkhurst CN, Chu C, Zhou L, Putzel GG, Li TT, Jin WB, Zhou J, JRI Live Cell Bank, Hu H, Tsou AM, Guo CJ, Artis D | Cell | 36240781 | Cell | 2022 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/36240781 |
Gut bacteria-derived serotonin promotes immune tolerance in early life. | Sanidad KZ, Rager SL, Carrow HC, Ananthanarayanan A, Callaghan R, Hart LR, Li T, Ravisankar P, Brown JA, Amir M, Jin JC, Savage AR, Luo R, Rowdo FM, Martin ML, Silver RB, Guo CJ, Krumsiek J, Inohara N, Zeng MY | Science immunology | 38489352 | Sci Immunol | 2024 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/38489352 |
Dietary fiber is a critical determinant of pathologic ILC2 responses and intestinal inflammation. | Arifuzzaman M, Won TH, Yano H, Uddin J, Emanuel ER, Hu E, Zhang W, Li TT, Jin WB, Grier A, Kashyap S, JRI Live Cell Bank, Guo CJ, Schroeder FC, Artis D | The Journal of experimental medicine | 38506708 | J Exp Med | 2024 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/38506708 |
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology. | Li TT, Chen X, Huo D, Arifuzzaman M, Qiao S, Jin WB, Shi H, Li XV, JRI Live Cell Bank Consortium, Iliev ID, Artis D, Guo CJ | Cell host & microbe | 38657606 | Cell Host Microbe | 2024 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/38657606 |
Depletion of microbiome-derived molecules in the host using Clostridium genetics. | Guo CJ, Allen BM, Hiam KJ, Dodd D, Van Treuren W, Higginbottom S, Nagashima K, Fischer CR, Sonnenburg JL, Spitzer MH, Fischbach MA | Science (New York, N.Y.) | 31831639 | Science | 2019 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/31831639 |
Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection. | Brown JA, Sanidad KZ, Lucotti S, Lieber CM, Cox RM, Ananthanarayanan A, Basu S, Chen J, Shan M, Amir M, Schmidt F, Weisblum Y, Cioffi M, Li T, Rowdo FM, Martin ML, Guo CJ, Lyssiotis C, Layden BT, Dannenberg AJ, Bieniasz PD, Lee B, Inohara N, Matei I, Plemper RK, Zeng MY | Gut microbes | 35915556 | Gut Microbes | 2022 Jan-Dec | https://www.ncbi.nlm.nih.gov/pubmed/35915556 |
Functional characterization of helminth-associated Clostridiales reveals covariates of Treg differentiation. | Sargsian S, Mondragón-Palomino O, Lejeune A, Ercelen D, Jin WB, Varghese A, Lim YAL, Guo CJ, Loke P, Cadwell K | Microbiome | 38730492 | Microbiome | 2024 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/38730492 |
Automated detection of axonal damage along white matter tracts in acute severe traumatic brain injury. | Maffei C, Gilmore N, Snider SB, Foulkes AS, Bodien YG, Yendiki A, Edlow BL | NeuroImage. Clinical | 36529035 | Neuroimage Clin | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36529035 |
Measuring Consciousness in the Intensive Care Unit. | Edlow BL, Fecchio M, Bodien YG, Comanducci A, Rosanova M, Casarotto S, Young MJ, Li J, Dougherty DD, Koch C, Tononi G, Massimini M, Boly M | Neurocritical care | 37029315 | Neurocrit Care | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37029315 |
Emerging Consciousness at a Clinical Crossroads. | Young MJ, Edlow BL | AJOB neuroscience | 33960885 | AJOB Neurosci | 2021 Apr-Sep | https://www.ncbi.nlm.nih.gov/pubmed/33960885 |
Update on neuroimaging in disorders of consciousness. | Sanz LRD, Thibaut A, Edlow BL, Laureys S, Gosseries O | Current opinion in neurology | 34054109 | Curr Opin Neurol | 2021 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/34054109 |
Joint cortical registration of geometry and function using semi-supervised learning. | Li J, Tuckute G, Fedorenko E, Edlow BL, Fischl B, Dalca AV | ArXiv | 37744470 | ArXiv | 2023 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/37744470 |
A state-space model for dynamic functional connectivity. | Chakravarty S, Threlkeld ZD, Bodien YG, Edlow BL, Brown EN | Conference record. Asilomar Conference on Signals, Systems & Computers | 32801606 | Conf Rec Asilomar Conf Signals Syst Comput | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32801606 |
Common Data Elements for COVID-19 Neuroimaging: A GCS-NeuroCOVID Proposal. | Edlow BL, Boly M, Chou SH, Fischer D, Kondziella D, Li LM, Mac Donald CL, McNett M, Newcombe VFJ, Stevens RD, Menon DK, GCS-NeuroCOVID | Neurocritical care | 33575956 | Neurocrit Care | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33575956 |
Personalized Connectome Mapping to Guide Targeted Therapy and Promote Recovery of Consciousness in the Intensive Care Unit. | Edlow BL, Barra ME, Zhou DW, Foulkes AS, Snider SB, Threlkeld ZD, Chakravarty S, Kirsch JE, Chan ST, Meisler SL, Bleck TP, Fins JJ, Giacino JT, Hochberg LR, Solt K, Brown EN, Bodien YG | Neurocritical care | 32794142 | Neurocrit Care | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32794142 |
Mapping the subcortical connectivity of the human default mode network. | Li J, Curley WH, Guerin B, Dougherty DD, Dalca AV, Fischl B, Horn A, Edlow BL | NeuroImage | 34838949 | Neuroimage | 2021 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/34838949 |
Common data elements for disorders of consciousness. | Edlow BL, Claassen J, Suarez JI | Neurocritical care | 38291278 | Neurocrit Care | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38291278 |
Model-based navigation of transcranial focused ultrasound neuromodulation in humans: Application to targeting the amygdala and thalamus. | Daneshzand M, Guerin B, Kotlarz P, Chou T, Dougherty DD, Edlow BL, Nummenmaa A | Brain stimulation | 39094682 | Brain Stimul | 2024 Jul-Aug | https://www.ncbi.nlm.nih.gov/pubmed/39094682 |
Cortical Lesion Expansion in Chronic Traumatic Brain Injury. | Freeman HJ, Atalay AS, Li J, Sobczak E, Gilmore N, Snider SB, Healy BC, Carrington H, Selmanovic E, Pruyser A, Bura L, Sheppard D, Hunt D, Seifert AC, Bodien YG, Hoffman JM, Mac Donald CL, Dams-O'Connor K, Edlow BL | medRxiv : the preprint server for health sciences | 38978662 | medRxiv | 2025 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/38978662 |
A human brain network linked to restoration of consciousness after deep brain stimulation. | Warren AEL, Raguž M, Friedrich H, Schaper FLWVJ, Tasserie J, Snider SB, Li J, Chua MMJ, Butenko K, Friedrich MU, Jha R, Iglesias JE, Carney PW, Fischer D, Fox MD, Boes AD, Edlow BL, Horn A, Chudy D, Rolston JD | medRxiv : the preprint server for health sciences | 39484242 | medRxiv | 2024 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/39484242 |
Cortical lesions and focal white matter injury are associated with attentional performance in chronic traumatic brain injury. | Snider SB, Gilmore N, Freeman HJ, Maffei C, Atalay A, Kumar RG, Li LM, Shi H, Bodien YG, Mac Donald CL, Dams-O'Connor K, Edlow BL | Brain communications | 39926612 | Brain Commun | 2025 | https://www.ncbi.nlm.nih.gov/pubmed/39926612 |
7 Tesla MRI of the ex vivo human brain at 100 micron resolution. | Edlow BL, Mareyam A, Horn A, Polimeni JR, Witzel T, Tisdall MD, Augustinack JC, Stockmann JP, Diamond BR, Stevens A, Tirrell LS, Folkerth RD, Wald LL, Fischl B, van der Kouwe A | Scientific data | 31666530 | Sci Data | 2019 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/31666530 |
EEG Correlates of Language Function in Traumatic Disorders of Consciousness. | Chatelle C, Rosenthal ES, Bodien YG, Spencer-Salmon CA, Giacino JT, Edlow BL | Neurocritical care | 31900883 | Neurocrit Care | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31900883 |
Ascending arousal network connectivity during recovery from traumatic coma. | Snider SB, Bodien YG, Frau-Pascual A, Bianciardi M, Foulkes AS, Edlow BL | NeuroImage. Clinical | 33395992 | Neuroimage Clin | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33395992 |
Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study. | Nolan AL, Petersen C, Iacono D, Mac Donald CL, Mukherjee P, van der Kouwe A, Jain S, Stevens A, Diamond BR, Wang R, Markowitz AJ, Fischl B, Perl DP, Manley GT, Keene CD, Diaz-Arrastia R, Edlow BL, TRACK-TBI Investigators | Journal of neurotrauma | 33412995 | J Neurotrauma | 2021 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/33412995 |
Early Seizures Are Predictive of Worse Health-Related Quality of Life at Follow-Up After Intracerebral Hemorrhage. | Naidech AM, Weaver B, Maas M, Bleck TP, VanHaerents S, Schuele SU | Critical care medicine | 33729725 | Crit Care Med | 2021 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/33729725 |
Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies. | Edlow BL, Claassen J, Schiff ND, Greer DM | Nature reviews. Neurology | 33318675 | Nat Rev Neurol | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33318675 |
Reemergence of the language network during recovery from severe traumatic brain injury: A pilot functional MRI study. | Coffey BJ, Threlkeld ZD, Foulkes AS, Bodien YG, Edlow BL | Brain injury | 34546806 | Brain Inj | 2021 Nov 10 | https://www.ncbi.nlm.nih.gov/pubmed/34546806 |
Dopaminergic modulation of human consciousness via default mode network connectivity. | Edlow BL | Proceedings of the National Academy of Sciences of the United States of America | 34330840 | Proc Natl Acad Sci U S A | 2021 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/34330840 |
Early Rehabilitation for Patients with Disorders of Consciousness after Severe COVID-19. | Edlow BL | Neurocritical care | 34617252 | Neurocrit Care | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/34617252 |
The Quest for Covert Consciousness: Bringing Neuroethics to the Bedside. | Young MJ, Edlow BL | Neurology | 33653901 | Neurology | 2021 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/33653901 |
Neuroprognostication: a conceptual framework. | Fischer D, Edlow BL, Giacino JT, Greer DM | Nature reviews. Neurology | 35352033 | Nat Rev Neurol | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35352033 |
Electrophysiological correlates of thalamocortical function in acute severe traumatic brain injury. | Curley WH, Bodien YG, Zhou DW, Conte MM, Foulkes AS, Giacino JT, Victor JD, Schiff ND, Edlow BL | Cortex; a journal devoted to the study of the nervous system and behavior | 35569326 | Cortex | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35569326 |
Predicting Functional Dependency in Patients with Disorders of Consciousness: A TBI-Model Systems and TRACK-TBI Study. | Snider SB, Temkin NR, Barber J, Edlow BL, Giacino JT, Hammond FM, Izzy S, Kowalski RG, Markowitz AJ, Rovito CA, Shih SL, Zafonte RD, Manley GT, Bodien YG, TRACK-TBI investigators | Annals of neurology | 37470289 | Ann Neurol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37470289 |
Severe cerebral edema in substance-related cardiac arrest patients. | Kulpanowski AM, Copen WA, Hancock BL, Rosenthal ES, Schoenfeld DA, Dodelson JA, Edlow BL, Kimberly WT, Amorim E, Westover MB, Ning MM, Schaefer PW, Malhotra R, Giacino JT, Greer DM, Wu O | Resuscitation | 35149137 | Resuscitation | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35149137 |
Conventional and Investigational Approaches Leveraging Clinical EEG for Prognosis in Acute Disorders of Consciousness. | Curley WH, Comanducci A, Fecchio M | Seminars in neurology | 36100227 | Semin Neurol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/36100227 |
Brain-Computer Interfaces for Communication in Patients with Disorders of Consciousness: A Gap Analysis and Scientific Roadmap. | Schiff ND, Diringer M, Diserens K, Edlow BL, Gosseries O, Hill NJ, Hochberg LR, Ismail FY, Meyer IA, Mikell CB, Mofakham S, Molteni E, Polizzotto L, Shah SA, Stevens RD, Thengone D, and the Curing Coma Campaign and its Contributing Members | Neurocritical care | 38286946 | Neurocrit Care | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38286946 |
Defining the boundary between life and death: New insights from neuropathology. | Edlow BL, Kinney HC | Journal of neuropathology and experimental neurology | 36519398 | J Neuropathol Exp Neurol | 2022 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/36519398 |
One-Year Outcomes in Disorders of Consciousness Associated with COVID-19. | Fischer D, Edlow BL | Neurocritical care | 36324001 | Neurocrit Care | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36324001 |
Correcting cardiorespiratory noise in resting-state functional MRI data acquired in critically ill patients. | Chan ST, Sanders WR, Fischer D, Kirsch JE, Napadow V, Bodien YG, Edlow BL | Brain communications | 36382222 | Brain Commun | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36382222 |
What is a minimal clinically important difference for clinical trials in patients with disorders of consciousness? a novel probabilistic approach. | Monti MM, Spivak NM, Edlow BL, Bodien YG | PloS one | 37616196 | PLoS One | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37616196 |
Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness. | Edlow BL, Olchanyi M, Freeman HJ, Li J, Maffei C, Snider SB, Zöllei L, Iglesias JE, Augustinack J, Bodien YG, Haynes RL, Greve DN, Diamond BR, Stevens A, Giacino JT, Destrieux C, van der Kouwe A, Brown EN, Folkerth RD, Fischl B, Kinney HC | Science translational medicine | 38691619 | Sci Transl Med | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38691619 |
Cross-regional coordination of activity in the human brain during autobiographical self-referential processing. | Stieger JR, Pinheiro-Chagas P, Fang Y, Li J, Lusk Z, Perry CM, Girn M, Contreras D, Chen Q, Huguenard JR, Spreng RN, Edlow BL, Wagner AD, Buch V, Parvizi J | Proceedings of the National Academy of Sciences of the United States of America | 39078679 | Proc Natl Acad Sci U S A | 2024 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/39078679 |
Three-dimensional fiber orientation mapping of the human brain at micrometer resolution. | Liu CJ, Ammon W, Jones RJ, Nolan JC, Gong D, Maffei C, Edlow BL, Augustinack JC, Magnain C, Yendiki A, Villiger M, Fischl B, Wang H | Research square | 39149445 | Res Sq | 2024 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/39149445 |
Automated Measurement of Cerebral Hemorrhagic Contusions and Outcomes After Traumatic Brain Injury in the TRACK-TBI Study. | Snider SB, Temkin NR, Sun X, Stubbs JL, Rademaker QJ, Markowitz AJ, Rosenthal ES, Diaz-Arrastia R, Fox MD, Manley GT, Jain S, Edlow BL, TRACK-TBI Investigators | JAMA network open | 39212991 | JAMA Netw Open | 2024 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/39212991 |
MRI in disorders of consciousness. | Snider SB, Edlow BL | Current opinion in neurology | 33044234 | Curr Opin Neurol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33044234 |
Unmasking Covert Language Processing in the Intensive Care Unit with Electroencephalography. | Edlow BL, Naccache L | Annals of neurology | 33491250 | Ann Neurol | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33491250 |
Multicenter prospective study on predictors of short-term outcome in disorders of consciousness. | Estraneo A, Fiorenza S, Magliacano A, Formisano R, Mattia D, Grippo A, Romoli AM, Angelakis E, Cassol H, Thibaut A, Gosseries O, Lamberti G, Noé E, Bagnato S, Edlow BL, Chatelle C, Lejeune N, Veeramuthu V, Bartolo M, Toppi J, Zasler N, Schnakers C, Trojano L, IBIA DoC-SIG | Neurology | 32661102 | Neurology | 2020 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/32661102 |
Toward Uniform Insurer Coverage for Functional MRI Following Severe Brain Injury. | Young MJ, Bodien YG, Freeman HJ, Fecchio M, Edlow BL | The Journal of head trauma rehabilitation | 36854104 | J Head Trauma Rehabil | 2023 Jul-Aug 01 | https://www.ncbi.nlm.nih.gov/pubmed/36854104 |
Sustaining wakefulness: Brainstem connectivity in human consciousness. | Edlow BL, Olchanyi M, Freeman HJ, Li J, Maffei C, Snider SB, Zöllei L, Iglesias JE, Augustinack J, Bodien YG, Haynes RL, Greve DN, Diamond BR, Stevens A, Giacino JT, Destrieux C, van der Kouwe A, Brown EN, Folkerth RD, Fischl B, Kinney HC | bioRxiv : the preprint server for biology | 37502983 | bioRxiv | 2023 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/37502983 |
Stability of extemporaneously prepared preservative-free methylphenidate 5 mg/mL intravenous solution. | Barra ME, Edlow BL, Lund JT, DeSanctis KS, Vetrano J, Reilly-Tremblay C, Zhang ER, Bodien YG, Brown EN, Solt K | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists | 34788364 | Am J Health Syst Pharm | 2022 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/34788364 |
Feasibility and Validity of the Coma Recovery Scale-Revised for Accelerated Standardized Testing: A Practical Assessment Tool for Detecting Consciousness in the Intensive Care Unit. | Bodien YG, Vora I, Barra A, Chiang K, Chatelle C, Goostrey K, Martens G, Malone C, Mello J, Parlman K, Ranford J, Sterling A, Waters AB, Hirschberg R, Katz DI, Mazwi N, Ni P, Velmahos G, Waak K, Edlow BL, Giacino JT | Annals of neurology | 37488068 | Ann Neurol | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37488068 |
Prognostication in Acute Neurological Emergencies. | Sloane KL, Miller JJ, Piquet A, Edlow BL, Rosenthal ES, Singhal AB | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | 35007934 | J Stroke Cerebrovasc Dis | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35007934 |
Risk factors for 2-year mortality in patients with prolonged disorders of consciousness: An international multicentre study. | Estraneo A, Magliacano A, Fiorenza S, Formisano R, Grippo A, Angelakis E, Cassol H, Thibaut A, Gosseries O, Lamberti G, Noé E, Bagnato S, Edlow BL, Chatelle C, Lejeune N, Veeramuthu V, Bartolo M, Mattia D, Toppi J, Zasler N, Schnakers C, Trojano L | European journal of neurology | 34657359 | Eur J Neurol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34657359 |
Mapping a memory disorder using functional network analysis. | Edlow BL | Acta neurologica Scandinavica | 34231225 | Acta Neurol Scand | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34231225 |
Joint super-resolution and synthesis of 1 mm isotropic MP-RAGE volumes from clinical MRI exams with scans of different orientation, resolution and contrast. | Iglesias JE, Billot B, Balbastre Y, Tabari A, Conklin J, Gilberto González R, Alexander DC, Golland P, Edlow BL, Fischl B, Alzheimer’s Disease Neuroimaging Initiative | NeuroImage | 34048902 | Neuroimage | 2021 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/34048902 |
Pharmacologic Therapies to Promote Recovery of Consciousness. | Barra ME, Edlow BL, Brophy GM | Seminars in neurology | 36100228 | Semin Neurol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/36100228 |
Disclosing Results of Tests for Covert Consciousness: A Framework for Ethical Translation. | Young MJ, Kazazian K, Fischer D, Lissak IA, Bodien YG, Edlow BL | Neurocritical care | 38243150 | Neurocrit Care | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38243150 |
SynthSR: A public AI tool to turn heterogeneous clinical brain scans into high-resolution T1-weighted images for 3D morphometry. | Iglesias JE, Billot B, Balbastre Y, Magdamo C, Arnold SE, Das S, Edlow BL, Alexander DC, Golland P, Fischl B | Science advances | 36724222 | Sci Adv | 2023 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/36724222 |
Characterizing coma in large vessel occlusion stroke. | Young MJ, Awad A, Andreev A, Bonkhoff AK, Schirmer MD, Dmytriw AA, Vranic JE, Rabinov JD, Doron O, Stapleton CJ, Das AS, Edlow BL, Singhal AB, Rost NS, Patel AB, Regenhardt RW | Journal of neurology | 38366071 | J Neurol | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38366071 |
Coma Prognostication After Acute Brain Injury: A Review. | Fischer D, Edlow BL | JAMA neurology | 38436946 | JAMA Neurol | 2024 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/38436946 |
Cognitive Motor Dissociation in Disorders of Consciousness. | Bodien YG, Allanson J, Cardone P, Bonhomme A, Carmona J, Chatelle C, Chennu S, Conte M, Dehaene S, Finoia P, Heinonen G, Hersh JE, Kamau E, Lawrence PK, Lupson VC, Meydan A, Rohaut B, Sanders WR, Sitt JD, Soddu A, Valente M, Velazquez A, Voss HU, Vrosgou A, Claassen J, Edlow BL, Fins JJ, Gosseries O, Laureys S, Menon D, Naccache L, Owen AM, Pickard J, Stamatakis EA, Thibaut A, Victor JD, Giacino JT, Bagiella E, Schiff ND | The New England journal of medicine | 39141852 | N Engl J Med | 2024 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/39141852 |
Visualizing Effective Connectivity in the Human Brain. | Atalay AS, Fecchio M, Edlow BL | bioRxiv : the preprint server for biology | 40161749 | bioRxiv | 2025 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/40161749 |
Acute biomarkers of consciousness are associated with recovery after severe traumatic brain injury. | Bodien YG, Fecchio M, Gilmore N, Freeman HJ, Sanders WR, Meydan A, Lawrence PK, Atalay AS, Kirsch J, Healy BC, Edlow BL | medRxiv : the preprint server for health sciences | 40093212 | medRxiv | 2025 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/40093212 |
Predicting Long-Term Recovery of Consciousness in Prolonged Disorders of Consciousness Based on Coma Recovery Scale-Revised Subscores: Validation of a Machine Learning-Based Prognostic Index. | Magliacano A, Liuzzi P, Formisano R, Grippo A, Angelakis E, Thibaut A, Gosseries O, Lamberti G, Noé E, Bagnato S, Edlow BL, Lejeune N, Veeramuthu V, Trojano L, Zasler N, Schnakers C, Bartolo M, Mannini A, Estraneo A, IBIA DoC-SIG | Brain sciences | 36672033 | Brain Sci | 2022 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/36672033 |
Prolonged Unconsciousness is Common in COVID-19 and Associated with Hypoxemia. | Waldrop G, Safavynia SA, Barra ME, Agarwal S, Berlin DA, Boehme AK, Brodie D, Choi JM, Doyle K, Fins JJ, Ganglberger W, Hoffman K, Mittel AM, Roh D, Mukerji SS, Der Nigoghossian C, Park S, Schenck EJ, Salazar-Schicchi J, Shen Q, Sholle E, Velazquez AG, Walline MC, Westover MB, Brown EN, Victor J, Edlow BL, Schiff ND, Claassen J | Annals of neurology | 35254675 | Ann Neurol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35254675 |
Transcranial Pulsed-Current Stimulation versus Transcranial Direct Current Stimulation in Patients with Disorders of Consciousness: A Pilot, Sham-Controlled Cross-Over Double-Blind Study. | Barra A, Rosenfelder M, Mortaheb S, Carrière M, Martens G, Bodien YG, Morales-Quezada L, Bender A, Laureys S, Thibaut A, Fregni F | Brain sciences | 35447961 | Brain Sci | 2022 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/35447961 |
Therapies to Restore Consciousness in Patients with Severe Brain Injuries: A Gap Analysis and Future Directions. | Edlow BL, Sanz LRD, Polizzotto L, Pouratian N, Rolston JD, Snider SB, Thibaut A, Stevens RD, Gosseries O, Curing Coma Campaign and its contributing members | Neurocritical care | 34236624 | Neurocrit Care | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34236624 |
Optimizing the accuracy of cortical volumetric analysis in traumatic brain injury. | Diamond BR, Donald CLM, Frau-Pascual A, Snider SB, Fischl B, Dams-O'Connor K, Edlow BL | MethodsX | 32760659 | MethodsX | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32760659 |
Location of Subcortical Microbleeds and Recovery of Consciousness After Severe Traumatic Brain Injury. | Bianciardi M, Izzy S, Rosen BR, Wald LL, Edlow BL | Neurology | 34050005 | Neurology | 2021 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/34050005 |
The neuroethics of disorders of consciousness: a brief history of evolving ideas. | Young MJ, Bodien YG, Giacino JT, Fins JJ, Truog RD, Hochberg LR, Edlow BL | Brain : a journal of neurology | 34347037 | Brain | 2021 Dec 16 | https://www.ncbi.nlm.nih.gov/pubmed/34347037 |
Long-Term Recovery from Disordered Consciousness Associated with COVID-19. | Fischer D, Edlow BL | Neurocritical care | 34642843 | Neurocrit Care | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34642843 |
Intact Brain Network Function in an Unresponsive Patient with COVID-19. | Fischer D, Threlkeld ZD, Bodien YG, Kirsch JE, Huang SY, Schaefer PW, Rapalino O, Hochberg LR, Rosen BR, Edlow BL | Annals of neurology | 32613682 | Ann Neurol | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32613682 |
Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19. | Conklin J, Frosch MP, Mukerji SS, Rapalino O, Maher MD, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, Shaw B, Lemieux JE, Sabeti PC, Branda JA, Brown EN, Westover MB, Huang SY, Edlow BL | Journal of the neurological sciences | 33497950 | J Neurol Sci | 2021 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/33497950 |
Recovery Potential in Patients Who Died After Withdrawal of Life-Sustaining Treatment: A TRACK-TBI Propensity Score Analysis. | Sanders WR, Barber JK, Temkin NR, Foreman B, Giacino JT, Williamson T, Edlow BL, Manley GT, Bodien YG | Journal of neurotrauma | 38739032 | J Neurotrauma | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38739032 |
Ictal fMRI: Mapping Seizure Topography with Rhythmic BOLD Oscillations. | Fischer D, Rapalino O, Fecchio M, Edlow BL | Brain sciences | 36552169 | Brain Sci | 2022 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/36552169 |
Increased task-relevant fMRI responsiveness in comatose cardiac arrest patients is associated with improved neurologic outcomes. | Dhakal K, Rosenthal ES, Kulpanowski AM, Dodelson JA, Wang Z, Cudemus-Deseda G, Villien M, Edlow BL, Presciutti AM, Januzzi JL, Ning M, Taylor Kimberly W, Amorim E, Brandon Westover M, Copen WA, Schaefer PW, Giacino JT, Greer DM, Wu O | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism | 37728641 | J Cereb Blood Flow Metab | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/37728641 |
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury. | Kumar RG, Selmanovic E, Gilmore N, Spielman L, Li LM, Hoffman JM, Bodien YG, Snider SB, Freeman HJ, de Souza NL, Donald CLM, Edlow BL, Dams-O'Connor K | medRxiv : the preprint server for health sciences | 39974133 | medRxiv | 2025 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/39974133 |
Covert cortical processing: a diagnosis in search of a definition. | Young MJ, Fecchio M, Bodien YG, Edlow BL | Neuroscience of consciousness | 38327828 | Neurosci Conscious | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38327828 |
Are disorders of consciousness 'dis'connection or 'dys'connection syndromes? | Edlow BL, Massimini M | Brain communications | 38410155 | Brain Commun | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/38410155 |
Quantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy. | Chen Y, Li S, Ge W, Jing J, Chen HY, Doherty D, Herman A, Kaleem S, Ding K, Osman G, Swisher CB, Smith C, Maciel CB, Alkhachroum A, Lee JW, Dhakar MB, Gilmore EJ, Sivaraju A, Hirsch LJ, Omay SB, Blumenfeld H, Sheth KN, Struck AF, Edlow BL, Westover MB, Kim JA | Journal of neurology, neurosurgery, and psychiatry | 36241423 | J Neurol Neurosurg Psychiatry | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36241423 |
Covert consciousness. | Young MJ, Edlow BL, Bodien YG | NeuroRehabilitation | 38217619 | NeuroRehabilitation | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38217619 |
Alpha coherence is a network signature of cognitive recovery from disorders of consciousness. | Zhou DW, Conte MM, Curley WH, Spencer-Salmon CA, Chatelle C, Rosenthal ES, Bodien YG, Victor JD, Schiff ND, Brown EN, Edlow BL | medRxiv : the preprint server for health sciences | 39417105 | medRxiv | 2024 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/39417105 |
Oral delivery of peptide therapeutics in infants: Challenges and opportunities. | Gleeson JP, Fein KC, Whitehead KA | Advanced drug delivery reviews | 33774115 | Adv Drug Deliv Rev | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33774115 |
The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery. | Lamson NG, Fein KC, Gleeson JP, Newby AN, Xian S, Cochran K, Chaudhary N, Melamed JR, Ball RL, Suri K, Ahuja V, Zhang A, Berger A, Kolodieznyi D, Schmidt BF, Silva GL, Whitehead KA | Proceedings of the National Academy of Sciences of the United States of America | 35943988 | Proc Natl Acad Sci U S A | 2022 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/35943988 |
Non-Viral RNA Delivery During Pregnancy: Opportunities and Challenges. | Chaudhary N, Newby AN, Whitehead KA | Small (Weinheim an der Bergstrasse, Germany) | 38145340 | Small | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38145340 |
Branched-Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice. | Petersen DMS, Weiss RM, Hajj KA, Yerneni SS, Chaudhary N, Newby AN, Arral ML, Whitehead KA | Advanced healthcare materials | 38888972 | Adv Healthc Mater | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/38888972 |
The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism. | Strelkova Petersen DM, Chaudhary N, Arral ML, Weiss RM, Whitehead KA | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V | 37838143 | Eur J Pharm Biopharm | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37838143 |
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs. | LoPresti ST, Arral ML, Chaudhary N, Whitehead KA | Journal of controlled release : official journal of the Controlled Release Society | 35346768 | J Control Release | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35346768 |
mRNA vaccines for infectious diseases: principles, delivery and clinical translation. | Chaudhary N, Weissman D, Whitehead KA | Nature reviews. Drug discovery | 34433919 | Nat Rev Drug Discov | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34433919 |
Placental drug transport and fetal exposure during pregnancy is determined by drug molecular size, chemistry, and conformation. | Fein KC, Arral ML, Kim JS, Newby AN, Whitehead KA | Journal of controlled release : official journal of the Controlled Release Society | 37473809 | J Control Release | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37473809 |
Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes. | Chaudhary N, Newby AN, Arral ML, Yerneni SS, LoPresti ST, Doerfler R, Petersen DMS, Montoya C, Kim JS, Fox B, Coon T, Malaney A, Sadovsky Y, Whitehead KA | Proceedings of the National Academy of Sciences of the United States of America | 38437545 | Proc Natl Acad Sci U S A | 2024 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/38437545 |
Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations. | Gleeson JP, Chaudhary N, Fein KC, Doerfler R, Hredzak-Showalter P, Whitehead KA | Science advances | 35767604 | Sci Adv | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35767604 |
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer. | Melamed JR, Yerneni SS, Arral ML, LoPresti ST, Chaudhary N, Sehrawat A, Muramatsu H, Alameh MG, Pardi N, Weissman D, Gittes GK, Whitehead KA | Science advances | 36706177 | Sci Adv | 2023 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/36706177 |
Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d. | Chaudhary N, Kasiewicz LN, Newby AN, Arral ML, Yerneni SS, Melamed JR, LoPresti ST, Fein KC, Strelkova Petersen DM, Kumar S, Purwar R, Whitehead KA | Nature biomedical engineering | 39363106 | Nat Biomed Eng | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39363106 |
Maternal milk cell components are uptaken by infant liver macrophages via extracellular vesicle mediated transport. | Doerfler R, Yerneni S, LoPresti S, Chaudhary N, Newby A, Melamed JR, Malaney A, Whitehead KA | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 39835705 | FASEB J | 2025 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/39835705 |
Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability. | Lamson NG, Berger A, Fein KC, Whitehead KA | Nature biomedical engineering | 31686002 | Nat Biomed Eng | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31686002 |
The Effect of Infant Gastric Digestion on Human Maternal Milk Cells. | Doerfler R, Melamed JR, Whitehead KA | Molecular nutrition & food research | 35984112 | Mol Nutr Food Res | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/35984112 |
Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery. | Melamed JR, Hajj KA, Chaudhary N, Strelkova D, Arral ML, Pardi N, Alameh MG, Miller JB, Farbiak L, Siegwart DJ, Weissman D, Whitehead KA | Journal of controlled release : official journal of the Controlled Release Society | 34801660 | J Control Release | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34801660 |
The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology. | Gleeson JP, Fein KC, Chaudhary N, Doerfler R, Newby AN, Whitehead KA | International journal of pharmaceutics | 33249250 | Int J Pharm | 2021 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/33249250 |
Enhanced epigenetic modulation via mRNA-encapsulated lipid nanoparticles enables targeted anti-inflammatory control. | Mokhtari T, Taheri MN, Akhlaghi S, Aryannejad A, Xiang Y, Mahajan V, Keshavarz K, Kiani A, LoPresti S, LeGraw R, Whitehead KA, Kiani S | bioRxiv : the preprint server for biology | 40060445 | bioRxiv | 2025 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/40060445 |
Characterization and comparison of human and mouse milk cells. | Doerfler R, Yerneni S, Newby A, Chaudhary N, Shu A, Fein K, Hofstatter Azambuja J, Whitehead KA | PloS one | 38295101 | PLoS One | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38295101 |
Heritability of Childhood Music Engagement and Associations with Language and Executive Function: Insights from the Adolescent Brain Cognitive Development (ABCD) Study. | Gustavson DE, Nayak S, Coleman PL, Iversen JR, Lense MD, Gordon RL, Maes HH | Behavior genetics | 36757558 | Behav Genet | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/36757558 |
The case for treatment fidelity in active music interventions: why and how. | Wiens N, Gordon RL | Annals of the New York Academy of Sciences | 29727027 | Ann N Y Acad Sci | 2018 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/29727027 |
Infants' neural speech discrimination predicts individual differences in grammar ability at 6 years of age and their risk of developing speech-language disorders. | Zhao TC, Boorom O, Kuhl PK, Gordon R | Developmental cognitive neuroscience | 33823366 | Dev Cogn Neurosci | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33823366 |
Does rhythmic priming improve grammatical processing in Hungarian-speaking children with and without developmental language disorder? | Ladányi E, Lukács Á, Gervain J | Developmental science | 34060171 | Dev Sci | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34060171 |
Synaptic processes and immune-related pathways implicated in Tourette syndrome. | Tsetsos F, Yu D, Sul JH, Huang AY, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau GA, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados MA, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Wagner M, Knowles JA, Jeremy Willsey A, Tischfield JA, Heiman GA, Cox NJ, Freimer NB, Neale BM, Davis LK, Coppola G, Mathews CA, Scharf JM, Paschou P, Tourette Association of America International Consortium for Genetics, Barr CL, Batterson JR, Berlin C, Budman CL, Cath DC, Coppola G, Cox NJ, Darrow S, Davis LK, Dion Y, Freimer NB, Grados MA, Greenberg E, Hirschtritt ME, Huang AY, Illmann C, King RA, Kurlan R, Leckman JF, Lyon GJ, Malaty IA, Mathews CA, McMahon WM, Neale BM, Okun MS, Osiecki L, Robertson MM, Rouleau GA, Sandor P, Scharf JM, Singer HS, Smit JH, Sul JH, Yu D, Gilles de la Tourette GWAS Replication Initiative, Aschauer HAH, Barta C, Budman CL, Cath DC, Depienne C, Hartmann A, Hebebrand J, Konstantinidis A, Mathews CA, Müller-Vahl K, Nagy P, Nöthen MM, Paschou P, Rizzo R, Rouleau GA, Sandor P, Scharf JM, Schlögelhofer M, Stamenkovic M, Stuhrmann M, Tsetsos F, Tarnok Z, Wolanczyk T, Worbe Y, Tourette International Collaborative Genetics Study, Brown L, Cheon KA, Coffey BJ, Dietrich A, Fernandez TV, Garcia-Delgar B, Gilbert D, Grice DE, Hagstrøm J, Hedderly T, Heiman GA, Heyman I, Hoekstra PJ, Huyser C, Kim YK, Kim YS, King RA, Koh YJ, Kook S, Kuperman S, Leventhal BL, Madruga-Garrido M, Mir P, Morer A, Münchau A, Plessen KJ, Roessner V, Shin EY, Song DH, Song J, Tischfield JA, Willsey AJ, Zinner S, Psychiatric Genomics Consortium Tourette Syndrome Working Group, Aschauer H, Barr CL, Barta C, Batterson JR, Berlin C, Brown L, Budman CL, Cath DC, Coffey BJ, Coppola G, Cox NJ, Darrow S, Davis LK, Depienne C, Dietrich A, Dion Y, Fernandez T, Freimer NB, Gilbert D, Grados MA, Greenberg E, Hartmann A, Hebebrand J, Heiman G, Hirschtritt ME, Hoekstra P, Huang AY, Illmann C, Jankovic J, King RA, Kuperman S, Lee PC, Lyon GJ, Malaty IA, Mathews CA, McMahon WM, Müller-Vahl K, Nagy P, Neale BM, Nöthen MM, Okun MS, Osiecki L, Paschou P, Rizzo R, Robertson MM, Rouleau GA, Sandor P, Scharf JM, Schlögelhofer M, Singer HS, Stamenkovic M, Stuhrmann M, Sul JH, Tarnok Z, Tischfield J, Tsetsos F, Willsey AJ, Woods D, Worbe Y, Yu D, Zinner S | Translational psychiatry | 33462189 | Transl Psychiatry | 2021 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/33462189 |
A neurodevelopmental disorders perspective into music, social attention, and social bonding. | Kasdan A, Gordon RL, Lense MD | The Behavioral and brain sciences | 34588066 | Behav Brain Sci | 2021 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/34588066 |
Identifying a brain network for musical rhythm: A functional neuroimaging meta-analysis and systematic review. | Kasdan AV, Burgess AN, Pizzagalli F, Scartozzi A, Chern A, Kotz SA, Wilson SM, Gordon RL | Neuroscience and biobehavioral reviews | 35259422 | Neurosci Biobehav Rev | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35259422 |
The shared genetic architecture and evolution of human language and musical rhythm. | Alagöz G, Eising E, Mekki Y, Bignardi G, Fontanillas P, 23andMe Research Team, Nivard MG, Luciano M, Cox NJ, Fisher SE, Gordon RL | bioRxiv : the preprint server for biology | 37961248 | bioRxiv | 2023 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/37961248 |
Linking the genomic signatures of human beat synchronization and learned song in birds. | Gordon RL, Ravignani A, Hyland Bruno J, Robinson CM, Scartozzi A, Embalabala R, Niarchou M, 23andMe Research Team, Cox NJ, Creanza N | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 34420388 | Philos Trans R Soc Lond B Biol Sci | 2021 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/34420388 |
Medical phenome of musicians: an investigation of health records collected on 9803 musically active individuals. | Niarchou M, Lin GT, Lense MD, Gordon RL, Davis LK | Annals of the New York Academy of Sciences | 34414577 | Ann N Y Acad Sci | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34414577 |
The Latent Genetic Structure of Impulsivity and Its Relation to Internalizing Psychopathology. | Gustavson DE, Friedman NP, Fontanillas P, Elson SL, 23andMe Research Team, Palmer AA, Sanchez-Roige S | Psychological science | 32716714 | Psychol Sci | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32716714 |
You got rhythm, or more: The multidimensionality of rhythmic abilities. | Fiveash A, Bella SD, Bigand E, Gordon RL, Tillmann B | Attention, perception & psychophysics | 35437703 | Atten Percept Psychophys | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35437703 |
Musical instrument engagement in adolescence predicts verbal ability 4 years later: A twin and adoption study. | Gustavson DE, Friedman NP, Stallings MC, Reynolds CA, Coon H, Corley RP, Hewitt JK, Gordon RL | Developmental psychology | 34914455 | Dev Psychol | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34914455 |
Neurophysiological Correlates of Dynamic Beat Tracking in Individuals With Williams Syndrome. | Kasdan A, Gordon RL, Lense MD | Biological psychiatry. Cognitive neuroscience and neuroimaging | 33419711 | Biol Psychiatry Cogn Neurosci Neuroimaging | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33419711 |
Processing rhythm in speech and music: Shared mechanisms and implications for developmental speech and language disorders. | Fiveash A, Bedoin N, Gordon RL, Tillmann B | Neuropsychology | 34435803 | Neuropsychology | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34435803 |
Regular rhythmic primes improve sentence repetition in children with developmental language disorder. | Fiveash A, Ladányi E, Camici J, Chidiac K, Bush CT, Canette LH, Bedoin N, Gordon RL, Tillmann B | NPJ science of learning | 37429839 | NPJ Sci Learn | 2023 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/37429839 |
Individual differences in neural markers of beat processing relate to spoken grammar skills in six-year-old children. | Persici V, Blain SD, Iversen JR, Key AP, Kotz SA, Devin McAuley J, Gordon RL | Brain and language | 37994830 | Brain Lang | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37994830 |
Exploring the genetics of rhythmic perception and musical engagement in the Vanderbilt Online Musicality Study. | Gustavson DE, Coleman PL, Wang Y, Nitin R, Petty LE, Bush CT, Mosing MA, Wesseldijk LW, Ullén F, 23 and Me Research Team, Below JE, Cox NJ, Gordon RL | Annals of the New York Academy of Sciences | 36718543 | Ann N Y Acad Sci | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36718543 |
The Musical Abilities, Pleiotropy, Language, and Environment (MAPLE) Framework for Understanding Musicality-Language Links Across the Lifespan. | Nayak S, Coleman PL, Ladányi E, Nitin R, Gustavson DE, Fisher SE, Magne CL, Gordon RL | Neurobiology of language (Cambridge, Mass.) | 36742012 | Neurobiol Lang (Camb) | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36742012 |
The Neural Correlates of Spontaneous Beat Processing and Its Relationship with Music-Related Characteristics of the Individual. | Scartozzi AC, Wang Y, Bush CT, Kasdan AV, Fram NR, Woynaroski T, Lense MD, Gordon RL, Ladányi E | eNeuro | 39401929 | eNeuro | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39401929 |
Interprofessional education of the next generation of musician-scientists through music cognition research training: An innovative platform for health professions and biomedical research. | Gordon RL, Lense MD | Music and medicine | 33603955 | Music Med | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33603955 |
Pushing the Envelope: Developments in Neural Entrainment to Speech and the Biological Underpinnings of Prosody Perception. | Myers BR, Lense MD, Gordon RL | Brain sciences | 30909454 | Brain Sci | 2019 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/30909454 |
New evidence of a rhythmic priming effect that enhances grammaticality judgments in children. | Chern A, Tillmann B, Vaughan C, Gordon RL | Journal of experimental child psychology | 29778278 | J Exp Child Psychol | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/29778278 |
Genome-wide association study of musical beat synchronization demonstrates high polygenicity. | Niarchou M, Gustavson DE, Sathirapongsasuti JF, Anglada-Tort M, Eising E, Bell E, McArthur E, Straub P, 23andMe Research Team, McAuley JD, Capra JA, Ullén F, Creanza N, Mosing MA, Hinds DA, Davis LK, Jacoby N, Gordon RL | Nature human behaviour | 35710621 | Nat Hum Behav | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/35710621 |
Exploring individual differences in musical rhythm and grammar skills in school-aged children with typically developing language. | Nitin R, Gustavson DE, Aaron AS, Boorom OA, Bush CT, Wiens N, Vaughan C, Persici V, Blain SD, Soman U, Hambrick DZ, Camarata SM, McAuley JD, Gordon RL | Scientific reports | 36750727 | Sci Rep | 2023 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/36750727 |
Using a polygenic score in a family design to understand genetic influences on musicality. | Wesseldijk LW, Abdellaoui A, Gordon RL, 23andMe Research Team, Ullén F, Mosing MA | Scientific reports | 36038631 | Sci Rep | 2022 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/36038631 |
Mental health and music engagement: review, framework, and guidelines for future studies. | Gustavson DE, Coleman PL, Iversen JR, Maes HH, Gordon RL, Lense MD | Translational psychiatry | 34226495 | Transl Psychiatry | 2021 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/34226495 |
Rhythm and timing as vulnerabilities in neurodevelopmental disorders. | Lense MD, Ladányi E, Rabinowitch TC, Trainor L, Gordon R | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 34420385 | Philos Trans R Soc Lond B Biol Sci | 2021 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/34420385 |
Is atypical rhythm a risk factor for developmental speech and language disorders? | Ladányi E, Persici V, Fiveash A, Tillmann B, Gordon RL | Wiley interdisciplinary reviews. Cognitive science | 32244259 | Wiley Interdiscip Rev Cogn Sci | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32244259 |
Genetic and Environmental Influences on Semantic Verbal Fluency Across Midlife and Later Life. | Gustavson DE, Panizzon MS, Kremen WS, Reynolds CA, Pahlen S, Nygaard M, Wod M, Catts VS, Lee T, Gatz M, Franz CE, IGEMS Consortium | Behavior genetics | 33547998 | Behav Genet | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33547998 |
Elevated Polygenic Burden for Autism Spectrum Disorder Is Associated With the Broad Autism Phenotype in Mothers of Individuals With Autism Spectrum Disorder. | Nayar K, Sealock JM, Maltman N, Bush L, Cook EH, Davis LK, Losh M | Biological psychiatry | 33229037 | Biol Psychiatry | 2021 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/33229037 |
Confronting ethical and social issues related to the genetics of musicality. | Gordon RL, Martschenko DO, Nayak S, Niarchou M, Morrison MD, Bell E, Jacoby N, Davis LK | Annals of the New York Academy of Sciences | 36851882 | Ann N Y Acad Sci | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36851882 |
The shared genetic architecture and evolution of human language and musical rhythm. | Alagöz G, Eising E, Mekki Y, Bignardi G, Fontanillas P, 23andMe Research Team, Nivard MG, Luciano M, Cox NJ, Fisher SE, Gordon RL | Nature human behaviour | 39572686 | Nat Hum Behav | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39572686 |
Targeted Rediscovery and Biosynthesis of the Farnesyl-Transferase Inhibitor Pepticinnamin E. | Santa Maria KC, Chan AN, O'Neill EM, Li B | Chembiochem : a European journal of chemical biology | 30694017 | Chembiochem | 2019 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/30694017 |
Chemoproteomics Reveals Disruption of Metal Homeostasis and Metalloproteins by the Antibiotic Holomycin. | Chan AN, Chen X, Falco JA, Bak DW, Weerapana E, Li B | ACS chemical biology | 37561838 | ACS Chem Biol | 2023 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/37561838 |
A Permissive Amide N-Methyltransferase for Dithiolopyrrolones. | Chen X, Johnson RM, Li B | ACS catalysis | 38106463 | ACS Catal | 2023 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/38106463 |
In Vitro Reconstitution Reveals a Central Role for the N-Oxygenase PvfB in (Dihydro)pyrazine-N-oxide and Valdiazen Biosynthesis. | Morgan GL, Li B | Angewandte Chemie (International ed. in English) | 32662921 | Angew Chem Int Ed Engl | 2020 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/32662921 |
Enzymatic Synthesis of Diverse Heterocycles by a Noncanonical Nonribosomal Peptide Synthetase. | Morgan GL, Li K, Crawford DM, Aubé J, Li B | ACS chemical biology | 34767712 | ACS Chem Biol | 2021 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/34767712 |
Pseudomonas Virulence Factor Pathway Synthesizes Autoinducers That Regulate the Secretome of a Pathogen. | Kretsch AM, Morgan GL, Acken KA, Barr SA, Li B | ACS chemical biology | 33595276 | ACS Chem Biol | 2021 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/33595276 |
Specificity of Nonribosomal Peptide Synthetases in the Biosynthesis of the Pseudomonas virulence factor. | Morgan GL, Kretsch AM, Santa Maria KC, Weeks SJ, Li B | Biochemistry | 31243997 | Biochemistry | 2019 Dec 31 | https://www.ncbi.nlm.nih.gov/pubmed/31243997 |
Pseudomonas virulence factor controls expression of virulence genes in Pseudomonas entomophila. | Acken KA, Li B | PloS one | 37200397 | PLoS One | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37200397 |
Activation of Dithiolopyrrolone Antibiotics by Cellular Reductants. | Steiner OM, Johnson RA, Chen X, Simke WC, Li B | Biochemistry | 39665630 | Biochemistry | 2025 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/39665630 |
Discovery and Biosynthesis of Azabicyclene, a Conserved Nonribosomal Peptide in Pseudomonas aeruginosa. | Patteson JB, Lescallette AR, Li B | Organic letters | 31247735 | Org Lett | 2019 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/31247735 |
Biosynthesis of fluopsin C, a copper-containing antibiotic from Pseudomonas aeruginosa. | Patteson JB, Putz AT, Tao L, Simke WC, Bryant LH 3rd, Britt RD, Li B | Science (New York, N.Y.) | 34793213 | Science | 2021 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/34793213 |
Inhibition of Isoleucyl-tRNA Synthetase by the Hybrid Antibiotic Thiomarinol. | Johnson RA, Chan AN, Ward RD, McGlade CA, Hatfield BM, Peters JM, Li B | Journal of the American Chemical Society | 34342433 | J Am Chem Soc | 2021 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/34342433 |
Discovery of (Dihydro)pyrazine N-Oxides via Genome Mining in Pseudomonas. | Kretsch AM, Morgan GL, Tyrrell J, Mevers E, Vallet-Gély I, Li B | Organic letters | 30073838 | Org Lett | 2018 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/30073838 |
Purification and characterization of tomato arginine decarboxylase and its inhibition by the bacterial small molecule phevamine A. | Guo Q, Chen X, Li B | Protein expression and purification | 37348664 | Protein Expr Purif | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37348664 |
The Hybrid Antibiotic Thiomarinol A Overcomes Intrinsic Resistance in Escherichia coli Using a Privileged Dithiolopyrrolone Moiety. | Johnson RM, Li K, Chen X, Morgan GL, Aubé J, Li B | ACS infectious diseases | 38226592 | ACS Infect Dis | 2024 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/38226592 |
"Rho"ing a Cellular Boat with Rearward Membrane Flow. | Bell GRR, Collins SR | Developmental cell | 29974859 | Dev Cell | 2018 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/29974859 |
Directional reorientation of migrating neutrophils is limited by suppression of receptor input signaling at the cell rear through myosin II activity. | Hadjitheodorou A, Bell GRR, Ellett F, Shastry S, Irimia D, Collins SR, Theriot JA | Nature communications | 34785640 | Nat Commun | 2021 Nov 16 | https://www.ncbi.nlm.nih.gov/pubmed/34785640 |
Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens. | Haney MS, Bohlen CJ, Morgens DW, Ousey JA, Barkal AA, Tsui CK, Ego BK, Levin R, Kamber RA, Collins H, Tucker A, Li A, Vorselen D, Labitigan L, Crane E, Boyle E, Jiang L, Chan J, Rincón E, Greenleaf WJ, Li B, Snyder MP, Weissman IL, Theriot JA, Collins SR, Barres BA, Bassik MC | Nature genetics | 30397336 | Nat Genet | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30397336 |
Optimized iLID Membrane Anchors for Local Optogenetic Protein Recruitment. | Natwick DE, Collins SR | ACS synthetic biology | 33843200 | ACS Synth Biol | 2021 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/33843200 |
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes. | Liou MJ, Miller BM, Litvak Y, Nguyen H, Natwick DE, Savage HP, Rixon JA, Mahan SP, Hiyoshi H, Rogers AWL, Velazquez EM, Butler BP, Collins SR, McSorley SJ, Harshey RM, Byndloss MX, Simon SI, Bäumler AJ | Cell host & microbe | 35568027 | Cell Host Microbe | 2022 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/35568027 |
Neutrophil-like cells derived from the HL-60 cell-line as a genetically-tractable model for neutrophil degranulation. | Bhakta SB, Lundgren SM, Sesti BN, Flores BA, Akdogan E, Collins SR, Mercer F | PloS one | 38324578 | PLoS One | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38324578 |
Whole-genome screens reveal regulators of differentiation state and context-dependent migration in human neutrophils. | Belliveau NM, Footer MJ, Akdoǧan E, van Loon AP, Collins SR, Theriot JA | Nature communications | 37723145 | Nat Commun | 2023 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/37723145 |
Decoding GEFs of animated cells. | Natwick DE, Collins SR | Nature chemical biology | 32694631 | Nat Chem Biol | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32694631 |
A map of gene expression in neutrophil-like cell lines. | Rincón E, Rocha-Gregg BL, Collins SR | BMC genomics | 30068296 | BMC Genomics | 2018 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/30068296 |
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors. | Lundgren SM, Rocha-Gregg BL, Akdoğan E, Mysore MN, Hayes S, Collins SR | Science signaling | 37788324 | Sci Signal | 2023 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/37788324 |
A complex of Wnt/planar cell polarity signaling components Vangl1 and Fzd7 drives glioblastoma multiforme malignant properties. | Dreyer CA, VanderVorst K, Natwick D, Bell G, Sood P, Hernandez M, Angelastro JM, Collins SR, Carraway KL 3rd | Cancer letters | 37336284 | Cancer Lett | 2023 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/37336284 |
Flagella-driven motility is a target of human Paneth cell defensin activity. | Akahoshi DT, Natwick DE, Yuan W, Lu W, Collins SR, Bevins CL | PLoS pathogens | 36821624 | PLoS Pathog | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36821624 |
Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing. | Bell GRR, Rincón E, Akdoğan E, Collins SR | Nature communications | 34785668 | Nat Commun | 2021 Nov 16 | https://www.ncbi.nlm.nih.gov/pubmed/34785668 |
Parallel High-Resolution Imaging of Leukocyte Chemotaxis Under Agarose with Rho-Family GTPase Biosensors. | Bell GRR, Natwick DE, Collins SR | Methods in molecular biology (Clifton, N.J.) | 30062406 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30062406 |
Leading edge competition promotes context-dependent responses to receptor inputs to resolve directional dilemmas in neutrophil migration. | Hadjitheodorou A, Bell GRR, Ellett F, Irimia D, Tibshirani R, Collins SR, Theriot JA | Cell systems | 36827986 | Cell Syst | 2023 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/36827986 |
Vangl-dependent Wnt/planar cell polarity signaling mediates collective breast carcinoma motility and distant metastasis. | VanderVorst K, Dreyer CA, Hatakeyama J, Bell GRR, Learn JA, Berg AL, Hernandez M, Lee H, Collins SR, Carraway KL 3rd | Breast cancer research : BCR | 37147680 | Breast Cancer Res | 2023 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/37147680 |
Modeling Subcellular Protein Recruitment Dynamics for Synthetic Biology. | Badu-Nkansah KA, Sernas D, Natwick DE, Collins SR | Methods in molecular biology (Clifton, N.J.) | 36227545 | Methods Mol Biol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36227545 |
Predictive modeling reveals that higher-order cooperativity drives transcriptional repression in a synthetic developmental enhancer. | Kim YJ, Rhee K, Liu J, Jeammet S, Turner MA, Small SJ, Garcia HG | eLife | 36503705 | Elife | 2022 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/36503705 |
Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila. | Child MB 6th, Bateman JR, Jahangiri A, Reimer A, Lammers NC, Sabouni N, Villamarin D, McKenzie-Smith GC, Johnson JE, Jost D, Garcia HG | eLife | 34100718 | Elife | 2021 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/34100718 |
Quantitative imaging of RNA polymerase II activity in plants reveals the single-cell basis of tissue-wide transcriptional dynamics. | Alamos S, Reimer A, Niyogi KK, Garcia HG | Nature plants | 34373604 | Nat Plants | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34373604 |
Kinetic sculpting of the seven stripes of the Drosophila even-skipped gene. | Berrocal A, Lammers NC, Garcia HG, Eisen MB | eLife | 33300492 | Elife | 2020 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/33300492 |
Minimal synthetic enhancers reveal control of the probability of transcriptional engagement and its timing by a morphogen gradient. | Alamos S, Reimer A, Westrum C, Turner MA, Talledo P, Zhao J, Luu E, Garcia HG | Cell systems | 36696901 | Cell Syst | 2023 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/36696901 |
Single cell biology-a Keystone Symposia report. | Cable J, Elowitz MB, Domingos AI, Habib N, Itzkovitz S, Hamidzada H, Balzer MS, Yanai I, Liberali P, Whited J, Streets A, Cai L, Stergachis AB, Hong CKY, Keren L, Guilliams M, Alon U, Shalek AK, Hamel R, Pfau SJ, Raj A, Quake SR, Zhang NR, Fan J, Trapnell C, Wang B, Greenwald NF, Vento-Tormo R, Santos SDM, Spencer SL, Garcia HG, Arekatla G, Gaiti F, Arbel-Goren R, Rulands S, Junker JP, Klein AM, Morris SA, Murray JI, Galloway KE, Ratz M, Romeike M | Annals of the New York Academy of Sciences | 34605044 | Ann N Y Acad Sci | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34605044 |
Quantitative dissection of transcription in development yields evidence for transcription-factor-driven chromatin accessibility. | Eck E, Liu J, Kazemzadeh-Atoufi M, Ghoreishi S, Blythe SA, Garcia HG | eLife | 33074101 | Elife | 2020 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/33074101 |
Genetically Encoded Fluorescent Biosensor for Rapid Detection of Protein Expression. | Eason MG, Pandelieva AT, Mayer MM, Khan ST, Garcia HG, Chica RA | ACS synthetic biology | 33044070 | ACS Synth Biol | 2020 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/33044070 |
Lighting up the central dogma for predictive developmental biology. | Garcia HG, Berrocal A, Kim YJ, Martini G, Zhao J | Current topics in developmental biology | 32143740 | Curr Top Dev Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32143740 |
A matter of time: Using dynamics and theory to uncover mechanisms of transcriptional bursting. | Lammers NC, Kim YJ, Zhao J, Garcia HG | Current opinion in cell biology | 33242838 | Curr Opin Cell Biol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33242838 |
The Drosophila Pioneer Factor Zelda Modulates the Nuclear Microenvironment of a Dorsal Target Enhancer to Potentiate Transcriptional Output. | Yamada S, Whitney PH, Huang SK, Eck EC, Garcia HG, Rushlow CA | Current biology : CB | 30982648 | Curr Biol | 2019 Apr 22 | https://www.ncbi.nlm.nih.gov/pubmed/30982648 |
Competing constraints shape the nonequilibrium limits of cellular decision-making. | Lammers NC, Flamholz AI, Garcia HG | Proceedings of the National Academy of Sciences of the United States of America | 36862689 | Proc Natl Acad Sci U S A | 2023 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/36862689 |
Single Molecule Imaging in Live Embryos Using Lattice Light-Sheet Microscopy. | Mir M, Reimer A, Stadler M, Tangara A, Hansen AS, Hockemeyer D, Eisen MB, Garcia H, Darzacq X | Methods in molecular biology (Clifton, N.J.) | 29956254 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29956254 |
LlamaTags: A Versatile Tool to Image Transcription Factor Dynamics in Live Embryos. | Bothma JP, Norstad MR, Alamos S, Garcia HG | Cell | 29754814 | Cell | 2018 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/29754814 |
Real-time single-cell characterization of the eukaryotic transcription cycle reveals correlations between RNA initiation, elongation, and cleavage. | Liu J, Hansen D, Eck E, Kim YJ, Turner M, Alamos S, Garcia HG | PLoS computational biology | 34003867 | PLoS Comput Biol | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/34003867 |
Figure 1 Theory Meets Figure 2 Experiments in the Study of Gene Expression. | Phillips R, Belliveau NM, Chure G, Garcia HG, Razo-Mejia M, Scholes C | Annual review of biophysics | 31084583 | Annu Rev Biophys | 2019 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/31084583 |
Multimodal transcriptional control of pattern formation in embryonic development. | Lammers NC, Galstyan V, Reimer A, Medin SA, Wiggins CH, Garcia HG | Proceedings of the National Academy of Sciences of the United States of America | 31882445 | Proc Natl Acad Sci U S A | 2020 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/31882445 |
Chromatin Changes in Phytochrome Interacting Factor-Regulated Genes Parallel Their Rapid Transcriptional Response to Light. | González-Grandío E, Álamos S, Zhang Y, Dalton-Roesler J, Niyogi KK, García HG, Quail PH | Frontiers in plant science | 35251080 | Front Plant Sci | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35251080 |
Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis. | Shami AN, Zheng X, Munyoki SK, Ma Q, Manske GL, Green CD, Sukhwani M, Orwig KE, Li JZ, Hammoud SS | Developmental cell | 32504559 | Dev Cell | 2020 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/32504559 |
Proteomic analysis of human sperm reveals changes in protamine 1 phosphorylation in men with infertility. | Schon SB, Moritz L, Rabbani M, Meguid J, Juliano BR, Ruotolo BT, Aston K, Hammoud SS | F&S science | 38065301 | F S Sci | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38065301 |
Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells. | Grill S, Bisht K, Tesmer VM, Shami AN, Hammoud SS, Nandakumar J | Cell reports | 31216472 | Cell Rep | 2019 Jun 18 | https://www.ncbi.nlm.nih.gov/pubmed/31216472 |
A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq. | Green CD, Ma Q, Manske GL, Shami AN, Zheng X, Marini S, Moritz L, Sultan C, Gurczynski SJ, Moore BB, Tallquist MD, Li JZ, Hammoud SS | Developmental cell | 30146481 | Dev Cell | 2018 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/30146481 |
Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline. | Graniel JV, Bisht K, Friedman A, White J, Perkey E, Vanderbeck A, Moroz A, Carrington LJ, Brandstadter JD, Allen F, Shami AN, Thomas P, Crayton A, Manzor M, Mychalowych A, Chase J, Hammoud SS, Keegan CE, Maillard I, Nandakumar J | Life science alliance | 34645668 | Life Sci Alliance | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34645668 |
Decoding the Spermatogenesis Program: New Insights from Transcriptomic Analyses. | Rabbani M, Zheng X, Manske GL, Vargo A, Shami AN, Li JZ, Hammoud SS | Annual review of genetics | 36070560 | Annu Rev Genet | 2022 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/36070560 |
TCF21(+) mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice. | Shen YC, Shami AN, Moritz L, Larose H, Manske GL, Ma Q, Zheng X, Sukhwani M, Czerwinski M, Sultan C, Chen H, Gurczynski SJ, Spence JR, Orwig KE, Tallquist M, Li JZ, Hammoud SS | Nature communications | 34162856 | Nat Commun | 2021 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/34162856 |
Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1. | Moritz L, Schon SB, Rabbani M, Sheng Y, Agrawal R, Glass-Klaiber J, Sultan C, Camarillo JM, Clements J, Baldwin MR, Diehl AG, Boyle AP, O'Brien PJ, Ragunathan K, Hu YC, Kelleher NL, Nandakumar J, Li JZ, Orwig KE, Redding S, Hammoud SS | Nature structural & molecular biology | 37460896 | Nat Struct Mol Biol | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37460896 |
Regulation of meiotic progression by Sertoli-cell androgen signaling. | Larose H, Kent T, Ma Q, Shami AN, Harerimana N, Li JZ, Hammoud SS, Handel MA | Molecular biology of the cell | 33026960 | Mol Biol Cell | 2020 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/33026960 |
Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq. | Ulrich ND, Shen YC, Ma Q, Yang K, Hannum DF, Jones A, Machlin J, Randolph JF Jr, Smith YR, Schon SB, Shikanov A, Marsh EE, Lieberman R, Gurczynski SJ, Moore BB, Li JZ, Hammoud S | Developmental cell | 35320732 | Dev Cell | 2022 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/35320732 |
The Art of Packaging the Sperm Genome: Molecular and Structural Basis of the Histone-To-Protamine Exchange. | Moritz L, Hammoud SS | Frontiers in endocrinology | 35813619 | Front Endocrinol (Lausanne) | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35813619 |
Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal women. | Ulrich ND, Vargo A, Ma Q, Shen YC, Bazzano D, Hannum DF, Gurczynski SJ, Moore BB, Schon S, Lieberman R, Shikanov A, Marsh EE, Fazleabas A, Li JZ, Hammoud SS | Proceedings of the National Academy of Sciences of the United States of America | 39471215 | Proc Natl Acad Sci U S A | 2024 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/39471215 |
Asymmetric Histone Inheritance Regulates Differential Transcription Re-initiation and Cell Fate Decisions in Mouse Olfactory Horizontal Basal Cells. | Ma B, Yang G, Yao J, Wu C, Vega JP, Manske G, Hammoud SS, Sinha S, Singh A, Zhao H, Chen X | bioRxiv : the preprint server for biology | 40093102 | bioRxiv | 2025 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/40093102 |
Natural language processing: put your model where your mouth is. | Haggerty RA, Purvis JE | Molecular systems biology | 29254950 | Mol Syst Biol | 2017 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/29254950 |
Autophagy regulates the localization and degradation of p16(INK4a). | Coryell PR, Goraya SK, Griffin KA, Redick MA, Sisk SR, Purvis JE | Aging cell | 32662244 | Aging Cell | 2020 Jul | https://www.ncbi.nlm.nih.gov/pubmed/32662244 |
A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics. | Burclaff J, Bliton RJ, Breau KA, Ok MT, Gomez-Martinez I, Ranek JS, Bhatt AP, Purvis JE, Woosley JT, Magness ST | Cellular and molecular gastroenterology and hepatology | 35176508 | Cell Mol Gastroenterol Hepatol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35176508 |
Inheritance of OCT4 predetermines fate choice in human embryonic stem cells. | Wolff SC, Kedziora KM, Dumitru R, Dungee CD, Zikry TM, Beltran AS, Haggerty RA, Cheng J, Redick MA, Purvis JE | Molecular systems biology | 30177503 | Mol Syst Biol | 2018 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/30177503 |
Orchestration of DNA Damage Checkpoint Dynamics across the Human Cell Cycle. | Chao HX, Poovey CE, Privette AA, Grant GD, Chao HY, Cook JG, Purvis JE | Cell systems | 29102360 | Cell Syst | 2017 Nov 22 | https://www.ncbi.nlm.nih.gov/pubmed/29102360 |
Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2. | Enrico TP, Stallaert W, Wick ET, Ngoi P, Wang X, Rubin SM, Brown NG, Purvis JE, Emanuele MJ | eLife | 34851822 | Elife | 2021 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/34851822 |
Accurate delineation of cell cycle phase transitions in living cells with PIP-FUCCI. | Grant GD, Kedziora KM, Limas JC, Cook JG, Purvis JE | Cell cycle (Georgetown, Tex.) | 30421640 | Cell Cycle | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30421640 |
The consequences of differential origin licensing dynamics in distinct chromatin environments. | Mei L, Kedziora KM, Song EA, Purvis JE, Cook JG | Nucleic acids research | 35079814 | Nucleic Acids Res | 2022 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/35079814 |
Integrating temporal single-cell gene expression modalities for trajectory inference and disease prediction. | Ranek JS, Stanley N, Purvis JE | Genome biology | 36064614 | Genome Biol | 2022 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/36064614 |
Bistable switches as integrators and actuators during cell cycle progression. | Stallaert W, Kedziora KM, Chao HX, Purvis JE | FEBS letters | 31566708 | FEBS Lett | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31566708 |
The Cell Cycle Browser: An Interactive Tool for Visualizing, Simulating, and Perturbing Cell-Cycle Progression. | Borland D, Yi H, Grant GD, Kedziora KM, Chao HX, Haggerty RA, Kumar J, Wolff SC, Cook JG, Purvis JE | Cell systems | 30077635 | Cell Syst | 2018 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/30077635 |
The structure of the human cell cycle. | Stallaert W, Kedziora KM, Taylor CD, Zikry TM, Ranek JS, Sobon HK, Taylor SR, Young CL, Cook JG, Purvis JE | Cell systems | 35051372 | Cell Syst | 2022 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/35051372 |
The structure of the human cell cycle. | Stallaert W, Kedziora KM, Taylor CD, Zikry TM, Ranek JS, Sobon HK, Taylor SR, Young CL, Cook JG, Purvis JE | Cell systems | 34800361 | Cell Syst | 2022 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/34800361 |
Inferring the structures of signaling motifs from paired dynamic traces of single cells. | Haggerty RA, Purvis JE | PLoS computational biology | 33539338 | PLoS Comput Biol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33539338 |
Chemical screen for epigenetic barriers to single allele activation of Oct4. | Headley KM, Kedziora KM, Alejo A, Lai EZ, Purvis JE, Hathaway NA | Stem cell research | 31170660 | Stem Cell Res | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31170660 |
Genetic determinants of cellular addiction to DNA polymerase theta. | Feng W, Simpson DA, Carvajal-Garcia J, Price BA, Kumar RJ, Mose LE, Wood RD, Rashid N, Purvis JE, Parker JS, Ramsden DA, Gupta GP | Nature communications | 31537809 | Nat Commun | 2019 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/31537809 |
Evidence that the human cell cycle is a series of uncoupled, memoryless phases. | Chao HX, Fakhreddin RI, Shimerov HK, Kedziora KM, Kumar RJ, Perez J, Limas JC, Grant GD, Cook JG, Gupta GP, Purvis JE | Molecular systems biology | 30886052 | Mol Syst Biol | 2019 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/30886052 |
Rapid DNA replication origin licensing protects stem cell pluripotency. | Matson JP, Dumitru R, Coryell P, Baxley RM, Chen W, Twaroski K, Webber BR, Tolar J, Bielinsky AK, Purvis JE, Cook JG | eLife | 29148972 | Elife | 2017 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/29148972 |
Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency. | Kumar RJ, Chao HX, Simpson DA, Feng W, Cho MG, Roberts VR, Sullivan AR, Shah SJ, Wozny AS, Fagan-Solis K, Kumar S, Luthman A, Ramsden DA, Purvis JE, Gupta GP | NAR cancer | 33385162 | NAR Cancer | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33385162 |
Cost-effectiveness of expanding the capacity of opioid agonist treatment in Ukraine: dynamic modeling analysis. | Morozova O, Crawford FW, Cohen T, Paltiel AD, Altice FL | Addiction (Abingdon, England) | 31478285 | Addiction | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31478285 |
Computational methods for birth-death processes. | Crawford FW, Ho LST, Suchard MA | Wiley interdisciplinary reviews. Computational statistics | 29942419 | Wiley Interdiscip Rev Comput Stat | 2018 Mar-Apr | https://www.ncbi.nlm.nih.gov/pubmed/29942419 |
Exposure, hazard, and survival analysis of diffusion on social networks. | Wu J, Crawford FW, Kim DA, Stafford D, Christakis NA | Statistics in medicine | 29707798 | Stat Med | 2018 Jul 30 | https://www.ncbi.nlm.nih.gov/pubmed/29707798 |
COVID-19 projections for reopening Connecticut. | Crawford FW, Li ZR, Morozova O | medRxiv : the preprint server for health sciences | 32588003 | medRxiv | 2020 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/32588003 |
SARS-CoV-2 attack rate and population immunity in southern New England, March 2020 - May 2021. | Tran TN, Wikle NB, Yang F, Inam H, Leighow S, Gentilesco B, Chan P, Albert E, Strong ER, Pritchard JR, Hanage WP, Hanks EM, Crawford FW, Boni MF | medRxiv : the preprint server for health sciences | 34909789 | medRxiv | 2021 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/34909789 |
Risk ratios for contagious outcomes. | Morozova O, Cohen T, Crawford FW | Journal of the Royal Society, Interface | 29343627 | J R Soc Interface | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29343627 |
Impact of close interpersonal contact on COVID-19 incidence: evidence from one year of mobile device data. | Crawford FW, Jones SA, Cartter M, Dean SG, Warren JL, Li ZR, Barbieri J, Campbell J, Kenney P, Valleau T, Morozova O | medRxiv : the preprint server for health sciences | 33758869 | medRxiv | 2021 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/33758869 |
Identification of causal intervention effects under contagion. | Cai X, Loh WW, Crawford FW | Journal of causal inference | 34676152 | J Causal Inference | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34676152 |
Dependence-Robust Confidence Intervals for Capture-Recapture Surveys. | Sun J, Van Baelen L, Plettinckx E, Crawford FW | Journal of survey statistics and methodology | 37975066 | J Surv Stat Methodol | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37975066 |
Estimating the Size of a Large Network and its Communities from a Random Sample. | Chen L, Karbasi A, Crawford FW | Advances in neural information processing systems | 28867924 | Adv Neural Inf Process Syst | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/28867924 |
An Adaptive Approach to Locating Mobile HIV Testing Services. | Gonsalves GS, Crawford FW, Cleary PD, Kaplan EH, Paltiel AD | Medical decision making : an international journal of the Society for Medical Decision Making | 28699382 | Med Decis Making | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/28699382 |
Empirical evidence of recruitment bias in a network study of people who inject drugs. | Zeng L, Li J, Crawford FW | The American journal of drug and alcohol abuse | 30896982 | Am J Drug Alcohol Abuse | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30896982 |
Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel. | Prunas O, Warren JL, Crawford FW, Gazit S, Patalon T, Weinberger DM, Pitzer VE | Science (New York, N.Y.) | 35084937 | Science | 2022 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/35084937 |
Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel. | Prunas O, Warren JL, Crawford FW, Gazit S, Patalon T, Weinberger DM, Pitzer VE | medRxiv : the preprint server for health sciences | 34981074 | medRxiv | 2021 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/34981074 |
Interpretation of the Individual Effect Under Treatment Spillover. | Crawford FW, Morozova O, Buchanan AL, Spiegelman D | American journal of epidemiology | 31094425 | Am J Epidemiol | 2019 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/31094425 |
Evaluating the Mediating Role of Recall of Intervention Knowledge in the Relationship Between a Peer-Driven Intervention and HIV Risk Behaviors Among People Who Inject Drugs. | Aroke H, Buchanan A, Katenka N, Crawford FW, Lee T, Halloran ME, Latkin C | AIDS and behavior | 35932359 | AIDS Behav | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35932359 |
Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks. | Dean NE, Gsell PS, Brookmeyer R, Crawford FW, Donnelly CA, Ellenberg SS, Fleming TR, Halloran ME, Horby P, Jaki T, Krause PR, Longini IM, Mulangu S, Muyembe-Tamfum JJ, Nason MC, Smith PG, Wang R, Henao-Restrepo AM, De Gruttola V | The New England journal of medicine | 32242365 | N Engl J Med | 2020 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/32242365 |
One year of modeling and forecasting COVID-19 transmission to support policymakers in Connecticut. | Morozova O, Li ZR, Crawford FW | medRxiv : the preprint server for health sciences | 32587978 | medRxiv | 2021 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/32587978 |
Violence and Discrimination Against Men Who Have Sex With Men in Lebanon: The Role of International Displacement and Migration. | Orr L, Shebl FM, Heimer R, Khoshnood K, Barbour R, Khouri D, Aaraj E, Mokhbat JE, Crawford FW | Journal of interpersonal violence | 31658847 | J Interpers Violence | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31658847 |
Estimates of people who injected drugs within the last 12 months in Belgium based on a capture-recapture and multiplier method. | Plettinckx E, Crawford FW, Antoine J, Gremeaux L, Van Baelen L | Drug and alcohol dependence | 33310486 | Drug Alcohol Depend | 2021 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/33310486 |
Transmission Modeling with Regression Adjustment for Analyzing Household-based Studies of Infectious Disease: Application to Tuberculosis. | Crawford FW, Marx FM, Zelner J, Cohen T | Epidemiology (Cambridge, Mass.) | 31764276 | Epidemiology | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31764276 |
Estimating the early death toll of COVID-19 in the United States. | Weinberger DM, Cohen T, Crawford FW, Mostashari F, Olson D, Pitzer VE, Reich NG, Russi M, Simonsen L, Watkins A, Viboud C | medRxiv : the preprint server for health sciences | 32511293 | medRxiv | 2020 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/32511293 |
Hidden population size estimation from respondent-driven sampling: a network approach. | Crawford FW, Wu J, Heimer R | Journal of the American Statistical Association | 30828120 | J Am Stat Assoc | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30828120 |
Predictors of Mortality within Prison and after Release among Persons Living with HIV in Indonesia. | Culbert GJ, Crawford FW, Murni A, Waluyo A, Bazazi AR, Sahar J, Altice FL | Research and reports in tropical medicine | 29238241 | Res Rep Trop Med | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29238241 |
HIV Risk, Prevalence, and Access to Care Among Men Who Have Sex with Men in Lebanon. | Heimer R, Barbour R, Khouri D, Crawford FW, Shebl F, Aaraj E, Khoshnood K | AIDS research and human retroviruses | 28540733 | AIDS Res Hum Retroviruses | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28540733 |
HIV Testing and awareness of HIV status among people who inject drugs in greater Kuala Lumpur, Malaysia. | Bazazi AR, Vijay A, Crawford FW, Heimer R, Kamarulzaman A, Altice FL | AIDS care | 28803503 | AIDS Care | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28803503 |
Randomized controlled trials of biomarker targets. | Erlendsdottir M, Crawford FW | Clinical trials (London, England) | 36373783 | Clin Trials | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36373783 |
Randomization for the susceptibility effect of an infectious disease intervention. | Eck DJ, Morozova O, Crawford FW | Journal of mathematical biology | 36127558 | J Math Biol | 2022 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/36127558 |
Impact of close interpersonal contact on COVID-19 incidence: Evidence from 1 year of mobile device data. | Crawford FW, Jones SA, Cartter M, Dean SG, Warren JL, Li ZR, Barbieri J, Campbell J, Kenney P, Valleau T, Morozova O | Science advances | 34995121 | Sci Adv | 2022 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/34995121 |
One year of modeling and forecasting COVID-19 transmission to support policymakers in Connecticut. | Morozova O, Li ZR, Crawford FW | Scientific reports | 34642405 | Sci Rep | 2021 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/34642405 |
Suspected heroin-related overdoses incidents in Cincinnati, Ohio: A spatiotemporal analysis. | Li ZR, Xie E, Crawford FW, Warren JL, McConnell K, Copple JT, Johnson T, Gonsalves GS | PLoS medicine | 31714940 | PLoS Med | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31714940 |
Opioid Agonist Treatment and Improved Outcomes at Each Stage of the HIV Treatment Cascade in People Who Inject Drugs in Ukraine. | Mazhnaya A, Marcus R, Bojko MJ, Zelenev A, Makarenko I, Pykalo I, Filippovych S, Dvoriak S, Altice FL | Journal of acquired immune deficiency syndromes (1999) | 30312275 | J Acquir Immune Defic Syndr | 2018 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/30312275 |
Estimating dose-specific cell division and apoptosis rates from chemo-sensitivity experiments. | Liu Y, Crawford FW | Scientific reports | 29426887 | Sci Rep | 2018 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/29426887 |
Divergent estimates of HIV incidence among people who inject drugs in Ukraine. | Morozova O, Booth RE, Dvoriak S, Dumchev K, Sazonova Y, Saliuk T, Crawford FW | The International journal on drug policy | 31405731 | Int J Drug Policy | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31405731 |
Using sigLASSO to optimize cancer mutation signatures jointly with sampling likelihood. | Li S, Crawford FW, Gerstein MB | Nature communications | 32681003 | Nat Commun | 2020 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/32681003 |
Dynamics of the HIV outbreak and response in Scott County, IN, USA, 2011-15: a modelling study. | Gonsalves GS, Crawford FW | The lancet. HIV | 30220531 | Lancet HIV | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30220531 |
The Burden of Stigma on Health and Well-Being: A Taxonomy of Concealment, Course, Disruptiveness, Aesthetics, Origin, and Peril Across 93 Stigmas. | Pachankis JE, Hatzenbuehler ML, Wang K, Burton CL, Crawford FW, Phelan JC, Link BG | Personality & social psychology bulletin | 29290150 | Pers Soc Psychol Bull | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29290150 |
Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009-2019. | Lu H, Crawford FW, Gonsalves GS, Grau LE | Annals of epidemiology | 36669599 | Ann Epidemiol | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36669599 |
Quantifying and Engineering Mucus Adhesion of Probiotics. | Mays ZJS, Chappell TC, Nair NU | ACS synthetic biology | 31909976 | ACS Synth Biol | 2020 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/31909976 |
Directed evolution of Anabaena variabilis phenylalanine ammonia-lyase (PAL) identifies mutants with enhanced activities. | Mays ZJ , Mohan K , Trivedi VD , Chappell TC , Nair NU | Chemical communications (Cambridge, England) | 32270162 | Chem Commun (Camb) | 2020 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/32270162 |
Synthetic biology in probiotic lactic acid bacteria: At the frontier of living therapeutics. | Mays ZJ, Nair NU | Current opinion in biotechnology | 29550614 | Curr Opin Biotechnol | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29550614 |
Specific codons control cellular resources and fitness. | Love AM, Nair NU | Science advances | 38381824 | Sci Adv | 2024 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/38381824 |
Towards universal synthetic heterotrophy using a metabolic coordinator. | Sullivan SF, Shetty A, Bharadwaj T, Krishna N, Trivedi VD, Endalur Gopinarayanan V, Chappell TC, Sellers DM, Pravin Kumar R, Nair NU | Metabolic engineering | 37406763 | Metab Eng | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37406763 |
A semi-synthetic regulon enables rapid growth of yeast on xylose. | Endalur Gopinarayanan V, Nair NU | Nature communications | 29581426 | Nat Commun | 2018 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/29581426 |
Cheating the Cheater: Suppressing False-Positive Enrichment during Biosensor-Guided Biocatalyst Engineering. | Trivedi VD, Mohan K, Chappell TC, Mays ZJS, Nair NU | ACS synthetic biology | 34914365 | ACS Synth Biol | 2022 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/34914365 |
Towards creating an extended metabolic model (EMM) for E. coli using enzyme promiscuity prediction and metabolomics data. | Amin SA, Chavez E, Porokhin V, Nair NU, Hassoun S | Microbial cell factories | 31196115 | Microb Cell Fact | 2019 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/31196115 |
Galactose to tagatose isomerization at moderate temperatures with high conversion and productivity. | Bober JR, Nair NU | Nature communications | 31591402 | Nat Commun | 2019 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/31591402 |
Toward a genetic tool development pipeline for host-associated bacteria. | Waller MC, Bober JR, Nair NU, Beisel CL | Current opinion in microbiology | 28624690 | Curr Opin Microbiol | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28624690 |
Engineered lactobacilli display anti-biofilm and growth suppressing activities against Pseudomonas aeruginosa. | Chappell TC, Nair NU | NPJ biofilms and microbiomes | 33127888 | NPJ Biofilms Microbiomes | 2020 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/33127888 |
A quantitative model for metabolic intervention using gut microbes. | Mays ZJS, Nair NU | Biotechnology progress | 33426814 | Biotechnol Prog | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/33426814 |
Characterization of a membrane enzymatic complex for heterologous production of poly-γ-glutamate in E. coli. | Motta Nascimento B, Nair NU | Metabolic engineering communications | 32963960 | Metab Eng Commun | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32963960 |
Pentose Metabolism in Saccharomyces cerevisiae: The Need to Engineer Global Regulatory Systems. | Endalur Gopinarayanan V, Nair NU | Biotechnology journal | 30171750 | Biotechnol J | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30171750 |
Establishing synthesis pathway-host compatibility via enzyme solubility. | Amin SA, Endalur Gopinarayanan V, Nair NU, Hassoun S | Biotechnology and bioengineering | 30802311 | Biotechnol Bioeng | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30802311 |
Synthetic Biology Approaches to Engineer Probiotics and Members of the Human Microbiota for Biomedical Applications. | Bober JR, Beisel CL, Nair NU | Annual review of biomedical engineering | 29528686 | Annu Rev Biomed Eng | 2018 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/29528686 |
Integration of metabolism and regulation reveals rapid adaptability to growth on non-native substrates. | Trivedi VD, Sullivan SF, Choudhury D, Endalur Gopinarayanan V, Hart T, Nair NU | Cell chemical biology | 37421944 | Cell Chem Biol | 2023 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/37421944 |
In-depth Sequence-Function Characterization Reveals Multiple Pathways to Enhance Enzymatic Activity. | Trivedi VD, Chappell TC, Krishna NB, Shetty A, Sigamani GG, Mohan K, Ramesh A, Pravin KR, Nair NU | ACS catalysis | 37325394 | ACS Catal | 2022 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/37325394 |
A Silk-Based Platform to Stabilize Phenylalanine Ammonia-lyase for Orally Administered Enzyme Replacement Therapy. | d'Amone L, Trivedi VD, Nair NU, Omenetto FG | Molecular pharmaceutics | 35862031 | Mol Pharm | 2022 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/35862031 |
Synthetic biomarkers: a twenty-first century path to early cancer detection. | Kwong GA, Ghosh S, Gamboa L, Patriotis C, Srivastava S, Bhatia SN | Nature reviews. Cancer | 34489588 | Nat Rev Cancer | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/34489588 |
Protease circuits for processing biological information. | Holt BA, Kwong GA | Nature communications | 33024117 | Nat Commun | 2020 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/33024117 |
AND-gated protease-activated nanosensors for programmable detection of anti-tumour immunity. | Sivakumar A, Phuengkham H, Rajesh H, Mac QD, Rogers LC, Silva Trenkle AD, Bawage SS, Hincapie R, Li Z, Vainikos S, Lee I, Xue M, Qiu P, Finn MG, Kwong GA | Nature nanotechnology | 39753733 | Nat Nanotechnol | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39753733 |
Remote Control of Mammalian Cells with Heat-Triggered Gene Switches and Photothermal Pulse Trains. | Miller IC, Gamboa Castro M, Maenza J, Weis JP, Kwong GA | ACS synthetic biology | 29579381 | ACS Synth Biol | 2018 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/29579381 |
In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles. | Su FY, Zhao QH, Dahotre SN, Gamboa L, Bawage SS, Silva Trenkle AD, Zamat A, Phuengkham H, Ahmed R, Santangelo PJ, Kwong GA | Science advances | 35196075 | Sci Adv | 2022 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/35196075 |
Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity. | Mac QD, Mathews DV, Kahla JA, Stoffers CM, Delmas OM, Holt BA, Adams AB, Kwong GA | Nature biomedical engineering | 30952979 | Nat Biomed Eng | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30952979 |
Synthetic Antigen-Presenting Cells for Adoptive T Cell Therapy. | Dahotre SN, Romanov AM, Su FY, Kwong GA | Advanced therapeutics | 34541300 | Adv Ther (Weinh) | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34541300 |
Macrophage Sensors for Early Cancer Detection. | Kwong GA | Clinical chemistry | 32040571 | Clin Chem | 2020 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/32040571 |
Synthetic immunity by remote control. | Gamboa L, Zamat AH, Kwong GA | Theranostics | 32206114 | Theranostics | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32206114 |
Deconvolving multiplexed protease signatures with substrate reduction and activity clustering. | Zhuang Q, Holt BA, Kwong GA, Qiu P | PLoS computational biology | 31479443 | PLoS Comput Biol | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31479443 |
Embracing enzyme promiscuity with activity-based compressed biosensing. | Holt BA, Lim HS, Sivakumar A, Phuengkham H, Su M, Tuttle M, Xu Y, Liakakos H, Qiu P, Kwong GA | Cell reports methods | 36814844 | Cell Rep Methods | 2023 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/36814844 |
Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics. | Holt BA, Mac QD, Kwong GA | Journal of visualized experiments : JoVE | 30059042 | J Vis Exp | 2018 Jul 16 | https://www.ncbi.nlm.nih.gov/pubmed/30059042 |
Interfacing Biomaterials with Synthetic T Cell Immunity. | Su FY, Mac QD, Sivakumar A, Kwong GA | Advanced healthcare materials | 33887123 | Adv Healthc Mater | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/33887123 |
DNA-Barcoded pMHC Tetramers for Detection of Single Antigen-Specific T Cells by Digital PCR. | Dahotre SN, Chang YM, Romanov AM, Kwong GA | Analytical chemistry | 30656939 | Anal Chem | 2019 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/30656939 |
Individually addressable and dynamic DNA gates for multiplexed cell sorting. | Dahotre SN, Chang YM, Wieland A, Stammen SR, Kwong GA | Proceedings of the National Academy of Sciences of the United States of America | 29632190 | Proc Natl Acad Sci U S A | 2018 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/29632190 |
Heat-Triggered Remote Control of CRISPR-dCas9 for Tunable Transcriptional Modulation. | Gamboa L, Phung EV, Li H, Meyers JP, Hart AC, Miller IC, Kwong GA | ACS chemical biology | 31904924 | ACS Chem Biol | 2020 Feb 21 | https://www.ncbi.nlm.nih.gov/pubmed/31904924 |
Urinary detection of early responses to checkpoint blockade and of resistance to it via protease-cleaved antibody-conjugated sensors. | Mac QD, Sivakumar A, Phuengkham H, Xu C, Bowen JR, Su FY, Stentz SZ, Sim H, Harris AM, Li TT, Qiu P, Kwong GA | Nature biomedical engineering | 35241815 | Nat Biomed Eng | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35241815 |
Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control. | Miller IC, Zamat A, Sun LK, Phuengkham H, Harris AM, Gamboa L, Yang J, Murad JP, Priceman SJ, Kwong GA | Nature biomedical engineering | 34385695 | Nat Biomed Eng | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34385695 |
Dimensionless parameter predicts bacterial prodrug success. | Holt BA, Tuttle M, Xu Y, Su M, Røise JJ, Wang X, Murthy N, Kwong GA | Molecular systems biology | 35005851 | Mol Syst Biol | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/35005851 |
A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution. | Packer JS, Zhu Q, Huynh C, Sivaramakrishnan P, Preston E, Dueck H, Stefanik D, Tan K, Trapnell C, Kim J, Waterston RH, Murray JI | Science (New York, N.Y.) | 31488706 | Science | 2019 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/31488706 |
Connect-seq to superimpose molecular on anatomical neural circuit maps. | Hanchate NK, Lee EJ, Ellis A, Kondoh K, Kuang D, Basom R, Trapnell C, Buck LB | Proceedings of the National Academy of Sciences of the United States of America | 32034095 | Proc Natl Acad Sci U S A | 2020 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/32034095 |
Inferring Causal Gene Regulatory Networks from Coupled Single-Cell Expression Dynamics Using Scribe. | Qiu X, Rahimzamani A, Wang L, Ren B, Mao Q, Durham T, McFaline-Figueroa JL, Saunders L, Trapnell C, Kannan S | Cell systems | 32135093 | Cell Syst | 2020 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/32135093 |
Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development. | Sharon N, Vanderhooft J, Straubhaar J, Mueller J, Chawla R, Zhou Q, Engquist EN, Trapnell C, Gifford DK, Melton DA | Cell reports | 31116975 | Cell Rep | 2019 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/31116975 |
Thyroid hormone regulates distinct paths to maturation in pigment cell lineages. | Saunders LM, Mishra AK, Aman AJ, Lewis VM, Toomey MB, Packer JS, Qiu X, McFaline-Figueroa JL, Corbo JC, Trapnell C, Parichy DM | eLife | 31140974 | Elife | 2019 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/31140974 |
The accessible chromatin landscape of the murine hippocampus at single-cell resolution. | Sinnamon JR, Torkenczy KA, Linhoff MW, Vitak SA, Mulqueen RM, Pliner HA, Trapnell C, Steemers FJ, Mandel G, Adey AC | Genome research | 30936163 | Genome Res | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30936163 |
Reversed graph embedding resolves complex single-cell trajectories. | Qiu X, Mao Q, Tang Y, Wang L, Chawla R, Pliner HA, Trapnell C | Nature methods | 28825705 | Nat Methods | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28825705 |
A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. | Gabrovsek L, Collins KB, Aggarwal S, Saunders LM, Lau HT, Suh D, Sancak Y, Trapnell C, Ong SE, Smith FD, Scott JD | The Journal of biological chemistry | 32482893 | J Biol Chem | 2020 Jul 31 | https://www.ncbi.nlm.nih.gov/pubmed/32482893 |
Defining cell types and states with single-cell genomics. | Trapnell C | Genome research | 26430159 | Genome Res | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26430159 |
Comprehensive single-cell transcriptional profiling of a multicellular organism. | Cao J, Packer JS, Ramani V, Cusanovich DA, Huynh C, Daza R, Qiu X, Lee C, Furlan SN, Steemers FJ, Adey A, Waterston RH, Trapnell C, Shendure J | Science (New York, N.Y.) | 28818938 | Science | 2017 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/28818938 |
Single-Cell Multi-omics: An Engine for New Quantitative Models of Gene Regulation. | Packer J, Trapnell C | Trends in genetics : TIG | 30007833 | Trends Genet | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30007833 |
Dynamics of Gene Expression in Single Root Cells of Arabidopsis thaliana. | Jean-Baptiste K, McFaline-Figueroa JL, Alexandre CM, Dorrity MW, Saunders L, Bubb KL, Trapnell C, Fields S, Queitsch C, Cuperus JT | The Plant cell | 30923229 | Plant Cell | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30923229 |
A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility. | Cusanovich DA, Hill AJ, Aghamirzaie D, Daza RM, Pliner HA, Berletch JB, Filippova GN, Huang X, Christiansen L, DeWitt WS, Lee C, Regalado SG, Read DF, Steemers FJ, Disteche CM, Trapnell C, Shendure J | Cell | 30078704 | Cell | 2018 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/30078704 |
Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data. | Pliner HA, Packer JS, McFaline-Figueroa JL, Cusanovich DA, Daza RM, Aghamirzaie D, Srivatsan S, Qiu X, Jackson D, Minkina A, Adey AC, Steemers FJ, Shendure J, Trapnell C | Molecular cell | 30078726 | Mol Cell | 2018 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/30078726 |
A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. | Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gürtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D | Cell | 30661759 | Cell | 2019 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/30661759 |
Sci-fate characterizes the dynamics of gene expression in single cells. | Cao J, Zhou W, Steemers F, Trapnell C, Shendure J | Nature biotechnology | 32284584 | Nat Biotechnol | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32284584 |
Massively multiplex chemical transcriptomics at single-cell resolution. | Srivatsan SR, McFaline-Figueroa JL, Ramani V, Saunders L, Cao J, Packer J, Pliner HA, Jackson DL, Daza RM, Christiansen L, Zhang F, Steemers F, Shendure J, Trapnell C | Science (New York, N.Y.) | 31806696 | Science | 2020 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/31806696 |
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy. | McFaline-Figueroa JL, Srivatsan S, Hill AJ, Gasperini M, Jackson DL, Saunders L, Domcke S, Regalado SG, Lazarchuck P, Alvarez S, Monnat RJ Jr, Shendure J, Trapnell C | bioRxiv : the preprint server for biology | 37398090 | bioRxiv | 2023 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/37398090 |
High-throughput, microscope-based sorting to dissect cellular heterogeneity. | Hasle N, Cooke A, Srivatsan S, Huang H, Stephany JJ, Krieger Z, Jackson D, Tang W, Pendyala S, Monnat RJ Jr, Trapnell C, Hatch EM, Fowler DM | Molecular systems biology | 32500953 | Mol Syst Biol | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32500953 |
A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition. | McFaline-Figueroa JL, Hill AJ, Qiu X, Jackson D, Shendure J, Trapnell C | Nature genetics | 31477929 | Nat Genet | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31477929 |
Dimensionality reduction by UMAP to visualize physical and genetic interactions. | Dorrity MW, Saunders LM, Queitsch C, Fields S, Trapnell C | Nature communications | 32210240 | Nat Commun | 2020 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/32210240 |
Activated CARD11 accelerates germinal center kinetics, promoting mTORC1 and terminal differentiation. | Wray-Dutra MN, Chawla R, Thomas KR, Seymour BJ, Arkatkar T, Sommer KM, Khim S, Trapnell C, James RG, Rawlings DJ | The Journal of experimental medicine | 30127060 | J Exp Med | 2018 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/30127060 |
Joint profiling of chromatin accessibility and gene expression in thousands of single cells. | Cao J, Cusanovich DA, Ramani V, Aghamirzaie D, Pliner HA, Hill AJ, Daza RM, McFaline-Figueroa JL, Packer JS, Christiansen L, Steemers FJ, Adey AC, Trapnell C, Shendure J | Science (New York, N.Y.) | 30166440 | Science | 2018 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/30166440 |
IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer. | Furlan SN, Singh K, Lopez C, Tkachev V, Hunt DJ, Hibbard J, Betz KM, Blazar BR, Trapnell C, Kean LS | Blood advances | 32311015 | Blood Adv | 2020 Apr 28 | https://www.ncbi.nlm.nih.gov/pubmed/32311015 |
Supervised classification enables rapid annotation of cell atlases. | Pliner HA, Shendure J, Trapnell C | Nature methods | 31501545 | Nat Methods | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31501545 |
Single-cell mRNA quantification and differential analysis with Census. | Qiu X, Hill A, Packer J, Lin D, Ma YA, Trapnell C | Nature methods | 28114287 | Nat Methods | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28114287 |
The single-cell transcriptional landscape of mammalian organogenesis. | Cao J, Spielmann M, Qiu X, Huang X, Ibrahim DM, Hill AJ, Zhang F, Mundlos S, Christiansen L, Steemers FJ, Trapnell C, Shendure J | Nature | 30787437 | Nature | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30787437 |
A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens. | Gasperini M, Hill AJ, McFaline-Figueroa JL, Martin B, Kim S, Zhang MD, Jackson D, Leith A, Schreiber J, Noble WS, Trapnell C, Ahituv N, Shendure J | Cell | 30612741 | Cell | 2019 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/30612741 |
On the design of CRISPR-based single-cell molecular screens. | Hill AJ, McFaline-Figueroa JL, Starita LM, Gasperini MJ, Matreyek KA, Packer J, Jackson D, Shendure J, Trapnell C | Nature methods | 29457792 | Nat Methods | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29457792 |
iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice. | Mucci A, Lopez-Rodriguez E, Hetzel M, Liu S, Suzuki T, Happle C, Ackermann M, Kempf H, Hillje R, Kunkiel J, Janosz E, Brennig S, Glage S, Bankstahl JP, Dettmer S, Rodt T, Gohring G, Trapnell B, Hansen G, Trapnell C, Knudsen L, Lachmann N, Moritz T | Stem cell reports | 30100408 | Stem Cell Reports | 2018 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/30100408 |
Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. | Cacchiarelli D, Qiu X, Srivatsan S, Manfredi A, Ziller M, Overbey E, Grimaldi A, Grimsby J, Pokharel P, Livak KJ, Li S, Meissner A, Mikkelsen TS, Rinn JL, Trapnell C | Cell systems | 30195438 | Cell Syst | 2018 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/30195438 |
Single-cell transcriptomics reveals receptor transformations during olfactory neurogenesis. | Hanchate NK, Kondoh K, Lu Z, Kuang D, Ye X, Qiu X, Pachter L, Trapnell C, Buck LB | Science (New York, N.Y.) | 26541607 | Science | 2015 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/26541607 |
Single-cell transcriptome sequencing: recent advances and remaining challenges. | Liu S, Trapnell C | F1000Research | 26949524 | F1000Res | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26949524 |
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy. | McFaline-Figueroa JL, Srivatsan S, Hill AJ, Gasperini M, Jackson DL, Saunders L, Domcke S, Regalado SG, Lazarchuck P, Alvarez S, Monnat RJ Jr, Shendure J, Trapnell C | Cell genomics | 38278156 | Cell Genom | 2024 Feb 14 | https://www.ncbi.nlm.nih.gov/pubmed/38278156 |
MaveDB 2024: a curated community database with over seven million variant effects from multiplexed functional assays. | Rubin AF, Stone J, Bianchi AH, Capodanno BJ, Da EY, Dias M, Esposito D, Frazer J, Fu Y, Grindstaff SB, Harrington MR, Li I, McEwen AE, Min JK, Moore N, Moscatelli OG, Ong J, Polunina PV, Rollins JE, Rollins NJ, Snyder AE, Tam A, Wakefield MJ, Ye SS, Starita LM, Bryant VL, Marks DS, Fowler DM | Genome biology | 39838450 | Genome Biol | 2025 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/39838450 |
Cortical neuroprosthetics from a clinical perspective. | Tsu AP, Burish MJ, GodLove J, Ganguly K | Neurobiology of disease | 26253606 | Neurobiol Dis | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26253606 |
Flexible regulation of representations on a drifting manifold enables long-term stable complex neuroprosthetic control. | Natraj N, Seko S, Abiri R, Yan H, Graham Y, Tu-Chan A, Chang EF, Ganguly K | bioRxiv : the preprint server for biology | 37645922 | bioRxiv | 2023 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/37645922 |
Compartmentalized dynamics within a common multi-area mesoscale manifold represent a repertoire of human hand movements. | Natraj N, Silversmith DB, Chang EF, Ganguly K | Neuron | 34678147 | Neuron | 2022 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/34678147 |
Plug-and-play control of a brain-computer interface through neural map stabilization. | Silversmith DB, Abiri R, Hardy NF, Natraj N, Tu-Chan A, Chang EF, Ganguly K | Nature biotechnology | 32895549 | Nat Biotechnol | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32895549 |
Sampling representational plasticity of simple imagined movements across days enables long-term neuroprosthetic control. | Natraj N, Seko S, Abiri R, Miao R, Yan H, Graham Y, Tu-Chan A, Chang EF, Ganguly K | Cell | 40054446 | Cell | 2025 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/40054446 |
Muscle synergies after stroke are correlated with perilesional high gamma. | Godlove J, Gulati T, Dichter B, Chang E, Ganguly K | Annals of clinical and translational neurology | 28097208 | Ann Clin Transl Neurol | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/28097208 |
Glycocalyx Scaffolding to Control Cell Surface Glycan Displays. | Huang ML, Tota EM, Verespy S 3rd, Godula K | Current protocols in chemical biology | 29927116 | Curr Protoc Chem Biol | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29927116 |
Synthetic glycoscapes: addressing the structural and functional complexity of the glycocalyx. | Purcell SC, Godula K | Interface focus | 30842878 | Interface Focus | 2019 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/30842878 |
Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism. | Trieger GW, Pessentheiner AR, Purcell SC, Green CR, DeForest N, Willert K, Majithia AR, Metallo CM, Godula K, Gordts PLSM | The Journal of biological chemistry | 36931394 | J Biol Chem | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/36931394 |
Embryonic Stem Cell Engineering with a Glycomimetic FGF2/BMP4 Co-Receptor Drives Mesodermal Differentiation in a Three-Dimensional Culture. | Naticchia MR, Laubach LK, Tota EM, Lucas TM, Huang ML, Godula K | ACS chemical biology | 30157624 | ACS Chem Biol | 2018 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/30157624 |
Influencing Early Stages of Neuromuscular Junction Formation through Glycocalyx Engineering. | Huang ML, Tota EM, Lucas TM, Godula K | ACS chemical neuroscience | 30095249 | ACS Chem Neurosci | 2018 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/30095249 |
Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. | Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD | Nature chemical biology | 33846619 | Nat Chem Biol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33846619 |
Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell-Matrix Interface. | Trieger GW, Verespy S 3rd, Gordts PLSM, Godula K | Bioconjugate chemistry | 30668905 | Bioconjug Chem | 2019 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/30668905 |
Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries. | Honigfort DJ, Zhang MH, Verespy S, Godula K | Faraday discussions | 31313786 | Faraday Discuss | 2019 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/31313786 |
Synthetic Mucus Nanobarriers for Identification of Glycan-Dependent Primary Influenza A Infection Inhibitors. | Cohen M, Senaati HP, Fisher CJ, Huang ML, Gagneux P, Godula K | ACS central science | 27800553 | ACS Cent Sci | 2016 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/27800553 |
Mucin-mimetic glycan arrays integrating machine learning for analyzing receptor pattern recognition by influenza A viruses. | Lucas TM, Gupta C, Altman MO, Sanchez E, Naticchia MR, Gagneux P, Singharoy A, Godula K | Chem | 34993358 | Chem | 2021 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/34993358 |
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. | Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD, Narayanan A, Majowicz SA, Kwong EM, McVicar RN, Thacker BE, Glass CA, Yang Z, Torres JL, Golden GJ, Bartels PL, Porell RN, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser BM, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Chanda SK, Schmidt AG, Godula K, Leibel SL, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD | Cell | 32970989 | Cell | 2020 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/32970989 |
Spatially controlled glycocalyx engineering for growth factor patterning in embryoid bodies. | Naticchia MR, Laubach LK, Honigfort DJ, Purcell SC, Godula K | Biomaterials science | 33409513 | Biomater Sci | 2021 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/33409513 |
Cell surface photoengineering enables modeling of glycocalyx shedding dynamics. | Purcell SC, Zhang MH, Honigfort DJ, Ng HJC, Michalak AL, Godula K | Chemical science | 35756522 | Chem Sci | 2022 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/35756522 |
Biologically Derived Neoproteoglycans for Profiling Protein-Glycosaminoglycan Interactions. | Porell RN, Follmar JL, Purcell SC, Timm B, Laubach LK, Kozirovskiy D, Thacker BE, Glass CA, Gordts PLSM, Godula K | ACS chemical biology | 35574759 | ACS Chem Biol | 2022 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/35574759 |
Glycocalyx Remodeling with Glycopolymer-Based Proteoglycan Mimetics. | Huang ML, Smith RA, Trieger GW, Godula K | Methods in molecular biology (Clifton, N.J.) | 26537476 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26537476 |
Heparin-fibronectin interactions in the development of extracellular matrix insolubility. | Raitman I, Huang ML, Williams SA, Friedman B, Godula K, Schwarzbauer JE | Matrix biology : journal of the International Society for Matrix Biology | 29223498 | Matrix Biol | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29223498 |
Glycomaterials for probing host-pathogen interactions and the immune response. | Huang ML, Fisher CJ, Godula K | Experimental biology and medicine (Maywood, N.J.) | 27190259 | Exp Biol Med (Maywood) | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27190259 |
Glycocalyx scaffolding with synthetic nanoscale glycomaterials. | Huang ML, Purcell SC, Verespy S III, Wang Y, Godula K | Biomaterials science | 28616946 | Biomater Sci | 2017 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/28616946 |
Stem Cell Microarrays for Assessing Growth Factor Signaling in Engineered Glycan Microenvironments. | Michalak AL, Trieger GW, Trieger KA, Godula K | Advanced healthcare materials | 34541824 | Adv Healthc Mater | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34541824 |
Small Molecule Antagonist of Cell Surface Glycosaminoglycans Restricts Mouse Embryonic Stem Cells in a Pluripotent State. | Huang ML, Michalak AL, Fisher CJ, Christy M, Smith RAA, Godula K | Stem cells (Dayton, Ohio) | 28984039 | Stem Cells | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28984039 |
Following sugar patterns in search of galectin function. | Godula K | Proceedings of the National Academy of Sciences of the United States of America | 29496962 | Proc Natl Acad Sci U S A | 2018 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/29496962 |
Silencing glycosaminoglycan functions in mouse embryonic stem cells with small molecule antagonists. | Chatterjee S, Stephenson TN, Michalak AL, Godula K, Huang ML | Methods in enzymology | 31606078 | Methods Enzymol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31606078 |
Glycocalyx crowding with mucin mimetics strengthens binding of soluble and virus-associated lectins to host cell glycan receptors. | Honigfort DJ, Altman MO, Gagneux P, Godula K | Proceedings of the National Academy of Sciences of the United States of America | 34583992 | Proc Natl Acad Sci U S A | 2021 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/34583992 |
Advances in Decoding Axolotl Limb Regeneration. | Haas BJ, Whited JL | Trends in genetics : TIG | 28648452 | Trends Genet | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28648452 |
Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution. | Leigh ND, Dunlap GS, Johnson K, Mariano R, Oshiro R, Wong AY, Bryant DM, Miller BM, Ratner A, Chen A, Ye WW, Haas BJ, Whited JL | Nature communications | 30514844 | Nat Commun | 2018 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/30514844 |
von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration. | Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL | Evolution & development | 32163674 | Evol Dev | 2020 Jul | https://www.ncbi.nlm.nih.gov/pubmed/32163674 |
Parallels between wound healing, epimorphic regeneration and solid tumors. | Wong AY, Whited JL | Development (Cambridge, England) | 31898582 | Development | 2020 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/31898582 |
Bioelectrical controls of morphogenesis: from ancient mechanisms of cell coordination to biomedical opportunities. | Whited JL, Levin M | Current opinion in genetics & development | 31442749 | Curr Opin Genet Dev | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31442749 |
Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration. | Sousounis K, Bryant DM, Martinez Fernandez J, Eddy SS, Tsai SL, Gundberg GC, Han J, Courtemanche K, Levin M, Whited JL | eLife | 32142407 | Elife | 2020 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/32142407 |
A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors. | Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM Jr, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL | Cell reports | 28099853 | Cell Rep | 2017 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/28099853 |
Common themes in tetrapod appendage regeneration: a cellular perspective. | Miller BM, Johnson K, Whited JL | EvoDevo | 31236203 | Evodevo | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31236203 |
Repeated removal of developing limb buds permanently reduces appendage size in the highly-regenerative axolotl. | Bryant DM, Sousounis K, Farkas JE, Bryant S, Thao N, Guzikowski AR, Monaghan JR, Levin M, Whited JL | Developmental biology | 28235582 | Dev Biol | 2017 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/28235582 |
Identification of regenerative roadblocks via repeat deployment of limb regeneration in axolotls. | Bryant DM, Sousounis K, Payzin-Dogru D, Bryant S, Sandoval AGW, Martinez Fernandez J, Mariano R, Oshiro R, Wong AY, Leigh ND, Johnson K, Whited JL | NPJ Regenerative medicine | 29302364 | NPJ Regen Med | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29302364 |
Complement Receptor C5aR1 Plays an Evolutionarily Conserved Role in Successful Cardiac Regeneration. | Natarajan N, Abbas Y, Bryant DM, Gonzalez-Rosa JM, Sharpe M, Uygur A, Cocco-Delgado LH, Ho NN, Gerard NP, Gerard CJ, MacRae CA, Burns CE, Burns CG, Whited JL, Lee RT | Circulation | 29348261 | Circulation | 2018 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/29348261 |
Systemic cell cycle activation is induced following complex tissue injury in axolotl. | Johnson K, Bateman J, DiTommaso T, Wong AY, Whited JL | Developmental biology | 29111100 | Dev Biol | 2018 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/29111100 |
Discussing limb development and regeneration in Barcelona: The future is at hand. | Rosello-Diez A, Whited JL | Developmental dynamics : an official publication of the American Association of Anatomists | 31587395 | Dev Dyn | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31587395 |
A Practical Guide for CRISPR-Cas9-Induced Mutations in Axolotls. | Sousounis K, Courtemanche K, Whited JL | Methods in molecular biology (Clifton, N.J.) | 36272086 | Methods Mol Biol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36272086 |
Automated home cage training of mice in a hold-still center-out reach task. | Bollu T, Whitehead SC, Prasad N, Walker J, Shyamkumar N, Subramaniam R, Kardon B, Cohen I, Goldberg JH | Journal of neurophysiology | 30540551 | J Neurophysiol | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30540551 |
Motor cortical inactivation impairs corrective submovements in mice performing a hold-still center-out reach task. | Bollu T, Whitehead SC, Prasad N, Walker J, Shyamkumar N, Subramaniam R, Kardon B, Cohen I, Goldberg JH | Journal of neurophysiology | 39081209 | J Neurophysiol | 2024 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/39081209 |
Cortex-dependent corrections as the tongue reaches for and misses targets. | Bollu T, Ito BS, Whitehead SC, Kardon B, Redd J, Liu MH, Goldberg JH | Nature | 34012117 | Nature | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34012117 |
Special issue on "recent advances in meiosis from DNA replication to chromosome segregation". | Cole F, Borde V | Chromosoma | 31616989 | Chromosoma | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31616989 |
2018 PLOS Genetics Research Prize: Bundling, stabilizing, organizing-The orchestration of acentriolar spindle assembly by microtubule motor proteins. | Barsh GS, Bhalla N, Cole F, Copenhaver GP, Lacefield S, Libuda DE | PLoS genetics | 30212501 | PLoS Genet | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30212501 |
Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes. | Zelazowski MJ, Sandoval M, Paniker L, Hamilton HM, Han J, Gribbell MA, Kang R, Cole F | Cell | 28942922 | Cell | 2017 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/28942922 |
X marks the spot: PRDM9 rescues hybrid sterility by finding hidden treasure in the genome. | Zelazowski MJ, Cole F | Nature structural & molecular biology | 27045445 | Nat Struct Mol Biol | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/27045445 |
Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance. | Takata KI, Reh S, Yousefzadeh MJ, Zelazowski MJ, Bhetawal S, Trono D, Lowery MG, Sandoval M, Takata Y, Lu Y, Lin K, Shen J, Kusewitt DF, McBride KM, Cole F, Wood RD | PLoS genetics | 28570559 | PLoS Genet | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28570559 |
53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1. | Li M, Cole F, Patel DS, Misenko SM, Her J, Malhowski A, Alhamza A, Zheng H, Baer R, Ludwig T, Jasin M, Nussenzweig A, Serrano L, Bunting SF | EMBO reports | 27670884 | EMBO Rep | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27670884 |
RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1. | Vélez-Cruz R, Manickavinayaham S, Biswas AK, Clary RW, Premkumar T, Cole F, Johnson DG | Genes & development | 27940962 | Genes Dev | 2016 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/27940962 |
SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. | Hansen RK, Mund A, Poulsen SL, Sandoval M, Klement K, Tsouroula K, Tollenaere MA, Räschle M, Soria R, Offermanns S, Worzfeld T, Grosse R, Brandt DT, Rozell B, Mann M, Cole F, Soutoglou E, Goodarzi AA, Daniel JA, Mailand N, Bekker-Jensen S | Nature cell biology | 27820601 | Nat Cell Biol | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27820601 |
Dynamic reorganization of the genome shapes the recombination landscape in meiotic prophase. | Patel L, Kang R, Rosenberg SC, Qiu Y, Raviram R, Chee S, Hu R, Ren B, Cole F, Corbett KD | Nature structural & molecular biology | 30778236 | Nat Struct Mol Biol | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30778236 |
Missing the Mark: PRDM9-Dependent Methylation Is Required for Meiotic DSB Targeting. | Kang R, Zelazowski MJ, Cole F | Molecular cell | 29499130 | Mol Cell | 2018 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/29499130 |
Genetic dissection of crossover mutants defines discrete intermediates in mouse meiosis. | Premkumar T, Paniker L, Kang R, Biot M, Humphrey E, Destain H, Ferranti I, Okulate I, Nguyen H, Kilaru V, Frasca M, Chakraborty P, Cole F | Molecular cell | 37595556 | Mol Cell | 2023 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/37595556 |
Transportability of Trial Results Using Inverse Odds of Sampling Weights. | Westreich D, Edwards JK, Lesko CR, Stuart E, Cole SR | American journal of epidemiology | 28535275 | Am J Epidemiol | 2017 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/28535275 |
Smoking, HIV, and risk of pregnancy loss. | Westreich D, Cates J, Cohen M, Weber KM, Seidman D, Cropsey K, Wright R, Milam J, Young MA, Mehta CC, Gustafson DR, Golub ET, Fischl MA, Adimora AA | AIDS (London, England) | 27902507 | AIDS | 2017 Feb 20 | https://www.ncbi.nlm.nih.gov/pubmed/27902507 |
Generalizing Study Results: A Potential Outcomes Perspective. | Lesko CR, Buchanan AL, Westreich D, Edwards JK, Hudgens MG, Cole SR | Epidemiology (Cambridge, Mass.) | 28346267 | Epidemiology | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28346267 |
Commentary: Epidemiology in the era of big data. | Mooney SJ, Westreich DJ, El-Sayed AM | Epidemiology (Cambridge, Mass.) | 25756221 | Epidemiology | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25756221 |
Risk. | Cole SR, Hudgens MG, Brookhart MA, Westreich D | American journal of epidemiology | 25660080 | Am J Epidemiol | 2015 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/25660080 |
Using Bounds to Compare the Strength of Exchangeability Assumptions for Internal and External Validity. | Breskin A, Westreich D, Cole SR, Edwards JK | American journal of epidemiology | 30834430 | Am J Epidemiol | 2019 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/30834430 |
UK Biobank, big data, and the consequences of non-representativeness. | Keyes KM, Westreich D | Lancet (London, England) | 30938313 | Lancet | 2019 Mar 30 | https://www.ncbi.nlm.nih.gov/pubmed/30938313 |
Generalizing Randomized Clinical Trial Results: Implementation and Challenges Related to Missing Data in the Target Population. | Hong JL, Jonsson Funk M, LoCasale R, Dempster SE, Cole SR, Webster-Clark M, Edwards JK, Stürmer T | American journal of epidemiology | 29020193 | Am J Epidemiol | 2018 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/29020193 |
The Authors Respond. | Lesko CR, Buchanan AL, Westreich D, Edwards JK, Hudgens MG, Cole SR | Epidemiology (Cambridge, Mass.) | 29023242 | Epidemiology | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29023242 |
From Patients to Policy: Population Intervention Effects in Epidemiology. | Westreich D | Epidemiology (Cambridge, Mass.) | 28282339 | Epidemiology | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28282339 |
When Is a Complete-Case Approach to Missing Data Valid? The Importance of Effect-Measure Modification. | Ross RK, Breskin A, Westreich D | American journal of epidemiology | 32601706 | Am J Epidemiol | 2020 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/32601706 |
Two-stage g-computation: Evaluating Treatment and Intervention Impacts in Observational Cohorts When Exposure Information Is Partly Missing. | Breger TL, Edwards JK, Cole SR, Westreich D, Pence BW, Adimora AA | Epidemiology (Cambridge, Mass.) | 32657953 | Epidemiology | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32657953 |
Causal Impact: Epidemiological Approaches for a Public Health of Consequence. | Westreich D, Edwards JK, Rogawski ET, Hudgens MG, Stuart EA, Cole SR | American journal of public health | 27153017 | Am J Public Health | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27153017 |
Brief Report: Estimating Differences and Ratios in Median Times to Event. | Rogawski ET, Westreich DJ, Kang G, Ward HD, Cole SR | Epidemiology (Cambridge, Mass.) | 27465526 | Epidemiology | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27465526 |
Invited commentary: every good randomization deserves observation. | Westreich D, Edwards JK | American journal of epidemiology | 26487342 | Am J Epidemiol | 2015 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/26487342 |
G-computation for policy-relevant effects of interventions on time-to-event outcomes. | Breskin A, Edmonds A, Cole SR, Westreich D, Cocohoba J, Cohen MH, Kassaye SG, Metsch LR, Sharma A, Williams MS, Adimora AA | International journal of epidemiology | 33141177 | Int J Epidemiol | 2021 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/33141177 |
A review of time scale fundamentals in the g-formula and insidious selection bias. | Keil AP, Edwards JK | Current epidemiology reports | 30555772 | Curr Epidemiol Rep | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30555772 |
The Effects of Hepatitis C Treatment Eligibility Criteria on All-cause Mortality Among People With Human Immunodeficiency Virus. | Breskin A, Westreich D, Hurt CB, Cole SR, Hudgens MG, Seaberg EC, Thio CL, Tien PC, Adimora AA | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 30615096 | Clin Infect Dis | 2019 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/30615096 |
Effect of Postnatal HIV Treatment on Clinical Mastitis and Breast Inflammation in HIV-Infected Breast-feeding Women. | Zadrozny S, Westreich D, Hudgens MG, Chasela C, Jamieson DJ, Martinson F, Zimba C, Tegha G, Hoffman I, Miller WC, Pence BW, King CC, Kourtis AP, Msungama W, van der Horst C, BAN Study Team | Paediatric and perinatal epidemiology | 28205255 | Paediatr Perinat Epidemiol | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28205255 |
Primary non-adherence and the new-user design. | Li X, Cole SR, Westreich D, Brookhart MA | Pharmacoepidemiology and drug safety | 29460385 | Pharmacoepidemiol Drug Saf | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29460385 |
Quantifying Cancer Risk from Radiation. | Keil AP, Richardson DB | Risk analysis : an official publication of the Society for Risk Analysis | 29211917 | Risk Anal | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29211917 |
Target Validity and the Hierarchy of Study Designs. | Westreich D, Edwards JK, Lesko CR, Cole SR, Stuart EA | American journal of epidemiology | 30299451 | Am J Epidemiol | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30299451 |
Generalizing the per-protocol treatment effect: The case of ACTG A5095. | Lu H, Cole SR, Hall HI, Schisterman EF, Breger TL, K Edwards J, Westreich D | Clinical trials (London, England) | 30326736 | Clin Trials | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30326736 |
Incident obstructive lung disease and mortality among people with HIV and a history of injecting drugs. | Kalmin MM, Westreich D, Drummond BM, Sun J, Mehta SH, Kirk GD | AIDS (London, England) | 33831913 | AIDS | 2021 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/33831913 |
A longitudinal, HIV care continuum: 10-year restricted mean time in each care continuum stage after enrollment in care, by history of IDU. | Lesko CR, Edwards JK, Moore RD, Lau B | AIDS (London, England) | 27314178 | AIDS | 2016 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/27314178 |
Exploring the Subtleties of Inverse Probability Weighting and Marginal Structural Models. | Breskin A, Cole SR, Westreich D | Epidemiology (Cambridge, Mass.) | 29384789 | Epidemiology | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29384789 |
Invited Commentary: Beware the Test-Negative Design. | Westreich D, Hudgens MG | American journal of epidemiology | 27587722 | Am J Epidemiol | 2016 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/27587722 |
Generalizability of randomized trial results to target populations: Design and analysis possibilities. | Stuart EA, Ackerman B, Westreich D | Research on social work practice | 30034203 | Res Soc Work Pract | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30034203 |
Body mass index, calcium supplementation and risk of colorectal adenomas. | Barry EL, Lund JL, Westreich D, Mott LA, Ahnen DJ, Beck GJ, Bostick RM, Bresalier RS, Burke CA, Church TR, Rees JR, Robertson DJ, Baron JA | International journal of cancer | 30117164 | Int J Cancer | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30117164 |
Comparison of Methods to Generalize Randomized Clinical Trial Results Without Individual-Level Data for the Target Population. | Hong JL, Webster-Clark M, Jonsson Funk M, Stürmer T, Dempster SE, Cole SR, Herr I, LoCasale R | American journal of epidemiology | 30312378 | Am J Epidemiol | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30312378 |
The Effects of Hepatitis C Infection and Treatment on All-cause Mortality Among People Living With Human Immunodeficiency Virus. | Breskin A, Westreich D, Cole SR, Hudgens MG, Hurt CB, Seaberg EC, Thio CL, Tien PC, Adimora AA | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 30321289 | Clin Infect Dis | 2019 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/30321289 |
Marginal Structural Models for Risk or Prevalence Ratios for a Point Exposure Using a Disease Risk Score. | Richardson DB, Keil AP, Kinlaw AC, Cole SR | American journal of epidemiology | 30726868 | Am J Epidemiol | 2019 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/30726868 |
The Impact of Implementation Fidelity on Mortality Under a CD4-Stratified Timing Strategy for Antiretroviral Therapy in Patients With Tuberculosis. | Patel MR, Westreich D, Yotebieng M, Nana M, Eron JJ, Behets F, Van Rie A | American journal of epidemiology | 25787266 | Am J Epidemiol | 2015 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/25787266 |
Thirteen Questions About Using Machine Learning in Causal Research (You Won't Believe the Answer to Number 10!). | Mooney SJ, Keil AP, Westreich DJ | American journal of epidemiology | 33751024 | Am J Epidemiol | 2021 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/33751024 |
The effect of early life antibiotic exposures on diarrheal rates among young children in Vellore, India. | Rogawski ET, Westreich D, Becker-Dreps S, Adair LS, Sandler RS, Sarkar R, Kattula D, Ward HD, Meshnick SR, Kang G | The Pediatric infectious disease journal | 25742244 | Pediatr Infect Dis J | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25742244 |
Age at Entry Into Care, Timing of Antiretroviral Therapy Initiation, and 10-Year Mortality Among HIV-Seropositive Adults in the United States. | Edwards JK, Cole SR, Westreich D, Mugavero MJ, Eron JJ, Moore RD, Mathews WC, Hunt P, Williams C, Centers for AIDS Research Network of Integrated Clinical Systems investigators | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 26082505 | Clin Infect Dis | 2015 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/26082505 |
You are smarter than you think: (super) machine learning in context. | Keil AP, Edwards JK | European journal of epidemiology | 29744711 | Eur J Epidemiol | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29744711 |
RESOLVING AN APPARENT PARADOX IN DOUBLY ROBUST ESTIMATORS. | Keil AP, Mooney SJ, Jonsson Funk M, Cole SR, Edwards JK, Westreich D | American journal of epidemiology | 29394330 | Am J Epidemiol | 2018 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/29394330 |
Toward a Clearer Definition of Selection Bias When Estimating Causal Effects. | Lu H, Cole SR, Howe CJ, Westreich D | Epidemiology (Cambridge, Mass.) | 35700187 | Epidemiology | 2022 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/35700187 |
Improving Depression Among HIV-Infected Adults: Transporting the Effect of a Depression Treatment Intervention to Routine Care. | Bengtson AM, Pence BW, Gaynes BN, Quinlivan EB, Heine AD, OʼDonnell JK, Crane HM, Mathews WC, Moore RD, Westreich D, OʼCleirigh C, Christopoulos K, Mimiaga MJ, Mugavero MJ | Journal of acquired immune deficiency syndromes (1999) | 27668804 | J Acquir Immune Defic Syndr | 2016 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/27668804 |
An Illustration of Inverse Probability Weighting to Estimate Policy-Relevant Causal Effects. | Edwards JK, Cole SR, Lesko CR, Mathews WC, Moore RD, Mugavero MJ, Westreich D | American journal of epidemiology | 27469514 | Am J Epidemiol | 2016 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/27469514 |
Baseline Characteristics Explain Differences in Effectiveness of Randomization to Daily Oral TDF/FTC PrEP Between Transgender Women and Cisgender Men Who Have Sex With Men in the iPrEx Trial. | Mehrotra ML, Westreich D, McMahan VM, Glymour MM, Geng E, Grant RM, Glidden DV | Journal of acquired immune deficiency syndromes (1999) | 31192894 | J Acquir Immune Defic Syndr | 2019 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/31192894 |
Transporting Subgroup Analyses of Randomized Controlled Trials for Planning Implementation of New Interventions. | Mehrotra ML, Westreich D, Glymour MM, Geng E, Glidden DV | American journal of epidemiology | 33615327 | Am J Epidemiol | 2021 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/33615327 |
The Authors Respond. | Breskin A, Cole SR, Hudgens MG | Epidemiology (Cambridge, Mass.) | 30052540 | Epidemiology | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30052540 |
Inverse Probability Weights for the Analysis of Polytomous Outcomes. | Richardson DB, Kinlaw AC, Keil AP, Naimi AI, Kaufman JS, Cole SR | American journal of epidemiology | 29390115 | Am J Epidemiol | 2018 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/29390115 |
An updated systematic review of epidemiological evidence on hormonal contraceptive methods and HIV acquisition in women. | Polis CB, Curtis KM, Hannaford PC, Phillips SJ, Chipato T, Kiarie JN, Westreich DJ, Steyn PS | AIDS (London, England) | 27500670 | AIDS | 2016 Nov 13 | https://www.ncbi.nlm.nih.gov/pubmed/27500670 |
Invited Commentary: Causal Inference Across Space and Time-Quixotic Quest, Worthy Goal, or Both? | Edwards JK, Lesko CR, Keil AP | American journal of epidemiology | 28679174 | Am J Epidemiol | 2017 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/28679174 |
Misclassification in defining and diagnosing microcephaly. | Kalmin MM, Gower EW, Stringer EM, Bowman NM, Rogawski McQuade ET, Westreich D | Paediatric and perinatal epidemiology | 31347726 | Paediatr Perinat Epidemiol | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31347726 |
Estimating the Impact of Changes to Occupational Standards for Silica Exposure on Lung Cancer Mortality. | Keil AP, Richardson DB, Westreich D, Steenland K | Epidemiology (Cambridge, Mass.) | 29870429 | Epidemiology | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/29870429 |
Use of electronic health record data and machine learning to identify candidates for HIV pre-exposure prophylaxis: a modelling study. | Marcus JL, Hurley LB, Krakower DS, Alexeeff S, Silverberg MJ, Volk JE | The lancet. HIV | 31285183 | Lancet HIV | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31285183 |
Early Life Antibiotic Exposure Is Not Associated with Growth in Young Children of Vellore, India. | Rogawski ET, Westreich DJ, Adair LS, Becker-Dreps S, Sandler RS, Sarkar R, Kattula D, Ward HD, Meshnick S, Kang G | The Journal of pediatrics | 26372535 | J Pediatr | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26372535 |
The effect of antiretroviral therapy on all-cause mortality, generalized to persons diagnosed with HIV in the USA, 2009-11. | Lesko CR, Cole SR, Hall HI, Westreich D, Miller WC, Eron JJ, Li J, Mugavero MJ, CNICS Investigators | International journal of epidemiology | 26772869 | Int J Epidemiol | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26772869 |
Reduction in diarrhoeal rates through interventions that prevent unnecessary antibiotic exposure early in life in an observational birth cohort. | Rogawski ET, Meshnick SR, Becker-Dreps S, Adair LS, Sandler RS, Sarkar R, Kattula D, Ward HD, Kang G, Westreich DJ | Journal of epidemiology and community health | 26621194 | J Epidemiol Community Health | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26621194 |
Use of Intrauterine Devices and Risk of Human Immunodeficiency Virus Acquisition Among Insured Women in the United States. | Marcus JL, Snowden JM, Murray Horwitz ME, Toh S, Horgan C, Tilney RC, Rajbhandari R, Back S, Westreich DJ | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 31412356 | Clin Infect Dis | 2020 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/31412356 |
The Intersections of COVID-19, HIV, and Race/Ethnicity: Machine Learning Methods to Identify and Model Risk Factors for Severe COVID-19 in a Large U.S. National Dataset. | Kunz M, Rott KW, Hurwitz E, Kunisaki K, Sun J, Wilkins KJ, Islam JY, Patel R, Safo SE, National Covid Cohort Collaborative (N3C) Consortium | AIDS and behavior | 38326668 | AIDS Behav | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38326668 |
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens. | Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC | Nature communications | 28474669 | Nat Commun | 2017 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/28474669 |
Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs. | Gu S, Zhang Y, Jin L, Huang Y, Zhang F, Bassik MC, Kampmann M, Kay MA | Nucleic acids research | 25270879 | Nucleic Acids Res | 2014 Oct 29 | https://www.ncbi.nlm.nih.gov/pubmed/25270879 |
CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity. | Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC | Nature chemical biology | 31451760 | Nat Chem Biol | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31451760 |
Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway. | Dubreuil MM, Morgens DW, Okumoto K, Honsho M, Contrepois K, Lee-McMullen B, Traber GM, Sood RS, Dixon SJ, Snyder MP, Fujiki Y, Bassik MC | Cell reports | 32023459 | Cell Rep | 2020 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/32023459 |
Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. | Jeng EE, Bhadkamkar V, Ibe NU, Gause H, Jiang L, Chan J, Jian R, Jimenez-Morales D, Stevenson E, Krogan NJ, Swaney DL, Snyder MP, Mukherjee S, Bassik MC | Cell host & microbe | 31540829 | Cell Host Microbe | 2019 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/31540829 |
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. | Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, Bassik MC, Aigner L, Wyss-Coray T | Nature neuroscience | 31959936 | Nat Neurosci | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31959936 |
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators. | Liu N, Lee CH, Swigut T, Grow E, Gu B, Bassik MC, Wysocka J | Nature | 29211708 | Nature | 2018 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/29211708 |
Next-generation libraries for robust RNA interference-based genome-wide screens. | Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS | Proceedings of the National Academy of Sciences of the United States of America | 26080438 | Proc Natl Acad Sci U S A | 2015 Jun 30 | https://www.ncbi.nlm.nih.gov/pubmed/26080438 |
SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy. | Wang Z, Hausmann S, Lyu R, Li TM, Lofgren SM, Flores NM, Fuentes ME, Caporicci M, Yang Z, Meiners MJ, Cheek MA, Howard SA, Zhang L, Elias JE, Kim MP, Maitra A, Wang H, Bassik MC, Keogh MC, Sage J, Gozani O, Mazur PK | Cancer cell | 32442403 | Cancer Cell | 2020 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/32442403 |
CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. | Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, Gitler AD | Nature genetics | 29507424 | Nat Genet | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29507424 |
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis. | Kamber RA, Nishiga Y, Morton B, Banuelos AM, Barkal AA, Vences-Catalán F, Gu M, Fernandez D, Seoane JA, Yao D, Liu K, Lin S, Spees K, Curtis C, Jerby-Arnon L, Weissman IL, Sage J, Bassik MC | Nature | 34497417 | Nature | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34497417 |
LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP. | Lahey LJ, Mardjuki RE, Wen X, Hess GT, Ritchie C, Carozza JA, Böhnert V, Maduke M, Bassik MC, Li L | Molecular cell | 33171122 | Mol Cell | 2020 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/33171122 |
Unraveling the mechanism of cell death induced by chemical fibrils. | Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA | Nature chemical biology | 25262416 | Nat Chem Biol | 2014 Nov | https://www.ncbi.nlm.nih.gov/pubmed/25262416 |
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. | Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS | Cell | 25307932 | Cell | 2014 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/25307932 |
Translation readthrough mitigation. | Arribere JA, Cenik ES, Jain N, Hess GT, Lee CH, Bassik MC, Fire AZ | Nature | 27281202 | Nature | 2016 Jun 30 | https://www.ncbi.nlm.nih.gov/pubmed/27281202 |
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. | Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC | Nature biotechnology | 28319085 | Nat Biotechnol | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28319085 |
KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics. | Milic B, Chakraborty A, Han K, Bassik MC, Block SM | Proceedings of the National Academy of Sciences of the United States of America | 29703754 | Proc Natl Acad Sci U S A | 2018 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/29703754 |
Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. | Hess GT, Frésard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC | Nature methods | 27798611 | Nat Methods | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27798611 |
Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs. | Lu A, Wawro P, Morgens DW, Portela F, Bassik MC, Pfeffer SR | eLife | 30556811 | Elife | 2018 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/30556811 |
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. | Liu S, Hausmann S, Carlson SM, Fuentes ME, Francis JW, Pillai R, Lofgren SM, Hulea L, Tandoc K, Lu J, Li A, Nguyen ND, Caporicci M, Kim MP, Maitra A, Wang H, Wistuba II, Porco JA Jr, Bassik MC, Elias JE, Song J, Topisirovic I, Van Rechem C, Mazur PK, Gozani O | Cell | 30612740 | Cell | 2019 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/30612740 |
Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes. | Morgens DW, Deans RM, Li A, Bassik MC | Nature biotechnology | 27159373 | Nat Biotechnol | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27159373 |
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes. | Wainberg M, Kamber RA, Balsubramani A, Meyers RM, Sinnott-Armstrong N, Hornburg D, Jiang L, Chan J, Jian R, Gu M, Shcherbina A, Dubreuil MM, Spees K, Meuleman W, Snyder MP, Bassik MC, Kundaje A | Nature genetics | 33859415 | Nat Genet | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33859415 |
Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins. | Morgens DW, Chan C, Kane AJ, Weir NR, Li A, Dubreuil MM, Tsui CK, Hess GT, Lavertu A, Han K, Polyakov N, Zhou J, Handy EL, Alabi P, Dombroski A, Yao D, Altman RB, Sello JK, Denic V, Bassik MC | eLife | 31674906 | Elife | 2019 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/31674906 |
Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages. | Cohen A, Jeng EE, Voorhies M, Symington J, Ali N, Rodriguez RA, Bassik MC, Sil A | PLoS pathogens | 36174103 | PLoS Pathog | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36174103 |
An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. | Coukos R, Yao D, Sanchez MI, Strand ET, Olive ME, Udeshi ND, Weissman JS, Carr SA, Bassik MC, Ting AY | eLife | 34414886 | Elife | 2021 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/34414886 |
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification. | Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC | Nature chemical biology | 27018887 | Nat Chem Biol | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27018887 |
E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia. | Duque-Afonso J, Lin CH, Han K, Wei MC, Feng J, Kurzer JH, Schneidawind C, Wong SH, Bassik MC, Cleary ML | Cancer research | 27758892 | Cancer Res | 2016 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/27758892 |
SLC19A1 Is an Importer of the Immunotransmitter cGAMP. | Ritchie C, Cordova AF, Hess GT, Bassik MC, Li L | Molecular cell | 31126740 | Mol Cell | 2019 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/31126740 |
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus. | Leonardi W, Zilbermintz L, Cheng LW, Zozaya J, Tran SH, Elliott JH, Polukhina K, Manasherob R, Li A, Chi X, Gharaibeh D, Kenny T, Zamani R, Soloveva V, Haddow AD, Nasar F, Bavari S, Bassik MC, Cohen SN, Levitin A, Martchenko M | Scientific reports | 27686742 | Sci Rep | 2016 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/27686742 |
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes. | Hess GT, Tycko J, Yao D, Bassik MC | Molecular cell | 28985508 | Mol Cell | 2017 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/28985508 |
Human pyrimidine nucleotide biosynthesis as a target for antiviral chemotherapy. | Okesli A, Khosla C, Bassik MC | Current opinion in biotechnology | 28458037 | Curr Opin Biotechnol | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/28458037 |
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities. | Han K, Pierce SE, Li A, Spees K, Anderson GR, Seoane JA, Lo YH, Dubreuil M, Olivas M, Kamber RA, Wainberg M, Kostyrko K, Kelly MR, Yousefi M, Simpkins SW, Yao D, Lee K, Kuo CJ, Jackson PK, Sweet-Cordero A, Kundaje A, Gentles AJ, Curtis C, Winslow MM, Bassik MC | Nature | 32238925 | Nature | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32238925 |
A genome-wide analysis of targets of macrolide antibiotics in mammalian cells. | Gupta A, Ökesli-Armlovich A, Morgens D, Bassik MC, Khosla C | The Journal of biological chemistry | 31915244 | J Biol Chem | 2020 Feb 14 | https://www.ncbi.nlm.nih.gov/pubmed/31915244 |
Phenome-based gene discovery provides information about Parkinson's disease drug targets. | Chen Y, Xu R | BMC genomics | 27586503 | BMC Genomics | 2016 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/27586503 |
Combining automatic table classification and relationship extraction in extracting anticancer drug-side effect pairs from full-text articles. | Xu R, Wang Q | Journal of biomedical informatics | 25445920 | J Biomed Inform | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25445920 |
Psoriasis and Psoriatic Arthritis Cardiovascular Disease Endotypes Identified by Red Blood Cell Distribution Width and Mean Platelet Volume. | Conic RR, Damiani G, Schrom KP, Ramser AE, Zheng C, Xu R, McCormick TS, Cooper KD | Journal of clinical medicine | 31936662 | J Clin Med | 2020 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/31936662 |
Association of Epigenetic Clock with Consensus Molecular Subtypes and Overall Survival of Colorectal Cancer. | Zheng C, Li L, Xu R | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology | 31375479 | Cancer Epidemiol Biomarkers Prev | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31375479 |
Disease comorbidity-guided drug repositioning: a case study in schizophrenia. | Wang Q, Xu R | AMIA ... Annual Symposium proceedings. AMIA Symposium | 30815174 | AMIA Annu Symp Proc | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30815174 |
Immunotherapy-related adverse events (irAEs): extraction from FDA drug labels and comparative analysis. | Wang Q, Xu R | JAMIA open | 30976759 | JAMIA Open | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30976759 |
Context-sensitive network analysis identifies food metabolites associated with Alzheimer's disease: an exploratory study. | Chen Y, Xu R | BMC medical genomics | 30704467 | BMC Med Genomics | 2019 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/30704467 |
Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment. | Nagaraj AB, Wang QQ, Joseph P, Zheng C, Chen Y, Kovalenko O, Singh S, Armstrong A, Resnick K, Zanotti K, Waggoner S, Xu R, DiFeo A | Oncogene | 28967908 | Oncogene | 2018 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/28967908 |
Epigenetic age acceleration and clinical outcomes in gliomas. | Zheng C, Berger NA, Li L, Xu R | PloS one | 32692766 | PLoS One | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32692766 |
PhenoPredict: A disease phenome-wide drug repositioning approach towards schizophrenia drug discovery. | Xu R, Wang Q | Journal of biomedical informatics | 26151312 | J Biomed Inform | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26151312 |
A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat. | Xu R, Wang Q, Li L | BMC genomics | 26100814 | BMC Genomics | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26100814 |
DenguePredict: An Integrated Drug Repositioning Approach towards Drug Discovery for Dengue. | Wang Q, Xu R | AMIA ... Annual Symposium proceedings. AMIA Symposium | 26958268 | AMIA Annu Symp Proc | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26958268 |
tcTKB: an integrated cardiovascular toxicity knowledge base for targeted cancer drugs. | Xu R, Wang Q | AMIA ... Annual Symposium proceedings. AMIA Symposium | 26958275 | AMIA Annu Symp Proc | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26958275 |
Large-scale automatic extraction of side effects associated with targeted anticancer drugs from full-text oncological articles. | Xu R, Wang Q | Journal of biomedical informatics | 25817969 | J Biomed Inform | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25817969 |
Disease Comorbidity Network Guides the Detection of Molecular Evidence for the Link Between Colorectal Cancer and Obesity. | Chen Y, Li L, Xu R | AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science | 26306270 | AMIA Jt Summits Transl Sci Proc | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26306270 |
GLP-1 Receptor Agonists and Colorectal Cancer Risk in Drug-Naive Patients With Type 2 Diabetes, With and Without Overweight/Obesity. | Wang L, Wang W, Kaelber DC, Xu R, Berger NA | JAMA oncology | 38060218 | JAMA Oncol | 2024 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/38060218 |
Integrin β3-Mediated Cell Senescence Associates with Gut Inflammation and Intestinal Degeneration in Models of Alzheimer's Disease. | Tun X, Wang EJ, Gao Z, Lundberg K, Xu R, Hu D | International journal of molecular sciences | 36982771 | Int J Mol Sci | 2023 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/36982771 |
A Drug-Side Effect Context-Sensitive Network approach for drug target prediction. | Zhou M, Chen Y, Xu R | Bioinformatics (Oxford, England) | 30428013 | Bioinformatics | 2019 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/30428013 |
Context-sensitive network-based disease genetics prediction and its implications in drug discovery. | Chen Y, Xu R | Bioinformatics (Oxford, England) | 28062449 | Bioinformatics | 2017 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/28062449 |
Association of Aspirin Use with Reduced Risk of Developing Alzheimer's Disease in Elderly Ischemic Stroke Patients: A Retrospective Cohort Study. | Gorenflo MP, Davis PB, Kendall EK, Olaker VR, Kaelber DC, Xu R | Journal of Alzheimer's disease : JAD | 36502331 | J Alzheimers Dis | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36502331 |
CoMNRank: An integrated approach to extract and prioritize human microbial metabolites from MEDLINE records. | Wang Q, Xu R | Journal of biomedical informatics | 32791237 | J Biomed Inform | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32791237 |
Drug repurposing for opioid use disorders: integration of computational prediction, clinical corroboration, and mechanism of action analyses. | Zhou M, Wang Q, Zheng C, John Rush A, Volkow ND, Xu R | Molecular psychiatry | 33432189 | Mol Psychiatry | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/33432189 |
A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease. | Shang Y, Sun X, Chen X, Wang Q, Wang EJ, Miller E, Xu R, Pieper AA, Qi X | Acta neuropathologica | 36104602 | Acta Neuropathol | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/36104602 |
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models. | Zhao Y, Hu D, Wang R, Sun X, Ropelewski P, Hubler Z, Lundberg K, Wang Q, Adams DJ, Xu R, Qi X | Nature communications | 35236834 | Nat Commun | 2022 Mar 2 | https://www.ncbi.nlm.nih.gov/pubmed/35236834 |
Glucagon-Like Peptide 1 Receptor Agonists and 13 Obesity-Associated Cancers in Patients With Type 2 Diabetes. | Wang L, Xu R, Kaelber DC, Berger NA | JAMA network open | 38967919 | JAMA Netw Open | 2024 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/38967919 |
Explore Small Molecule-induced Genome-wide Transcriptional Profiles for Novel Inflammatory Bowel Disease Drug. | Cai X, Chen Y, Gao Z, Xu R | AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science | 27570643 | AMIA Jt Summits Transl Sci Proc | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27570643 |
Combining Human Disease Genetics and Mouse Model Phenotypes towards Drug Repositioning for Parkinson's disease. | Chen Y, Cai X, Xu R | AMIA ... Annual Symposium proceedings. AMIA Symposium | 26958284 | AMIA Annu Symp Proc | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26958284 |
Combining mechanism-based prediction with patient-based profiling for psoriasis metabolomics biomarker discovery. | Wang Q, McCormick TS, Ward NL, Cooper KD, Conic R, Xu R | AMIA ... Annual Symposium proceedings. AMIA Symposium | 29854244 | AMIA Annu Symp Proc | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29854244 |
MetabolitePredict: A de novo human metabolomics prediction system and its applications in rheumatoid arthritis. | Wang Q, Xu R | Journal of biomedical informatics | 28600026 | J Biomed Inform | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28600026 |
Predict drug permeability to blood-brain-barrier from clinical phenotypes: drug side effects and drug indications. | Gao Z, Chen Y, Cai X, Xu R | Bioinformatics (Oxford, England) | 27993785 | Bioinformatics | 2017 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/27993785 |
Drug repurposing for glioblastoma based on molecular subtypes. | Chen Y, Xu R | Journal of biomedical informatics | 27697594 | J Biomed Inform | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27697594 |
Evaluating class III antiarrhythmic agents as novel MYC targeting drugs in ovarian cancer. | Belur Nagaraj A, Joseph P, Kovalenko O, Wang Q, Xu R, DiFeo A | Gynecologic oncology | 30301560 | Gynecol Oncol | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30301560 |
Automatic construction of a large-scale and accurate drug-side-effect association knowledge base from biomedical literature. | Xu R, Wang Q | Journal of biomedical informatics | 24928448 | J Biomed Inform | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/24928448 |
Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. | Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R | Alzheimer's & dementia : the journal of the Alzheimer's Association | 34569707 | Alzheimers Dement | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34569707 |
Analysis of disease organ as a novel phenotype towards disease genetics understanding. | Luo L, Zheng C, Wang J, Tan M, Li Y, Xu R | Journal of biomedical informatics | 31207382 | J Biomed Inform | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31207382 |
Tumor Necrosis Factor (TNF) blocking agents are associated with lower risk for Alzheimer's disease in patients with rheumatoid arthritis and psoriasis. | Zhou M, Xu R, Kaelber DC, Gurney ME | PloS one | 32203525 | PLoS One | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32203525 |
Correction: COVID-19 risk and outcomes in patients with substance use disorders: analyses from electronic health records in the United States. | Wang QQ, Kaelber DC, Xu R, Volkow ND | Molecular psychiatry | 32999436 | Mol Psychiatry | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32999436 |
COVID-19 risk, disparities and outcomes in patients with chronic liver disease in the United States. | Wang Q, Davis PB, Xu R | EClinicalMedicine | 33521611 | EClinicalMedicine | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33521611 |
COVID-19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US. | Wang Q, Davis PB, Gurney ME, Xu R | Alzheimer's & dementia : the journal of the Alzheimer's Association | 33559975 | Alzheimers Dement | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/33559975 |
When hematologic malignancies meet COVID-19 in the United States: Infections, death and disparities. | Wang Q, Berger NA, Xu R | Blood reviews | 33187811 | Blood Rev | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33187811 |
Aspirin Use and Risk of Alzheimer's Disease: A 2-Sample Mendelian Randomization Study. | Ding P, Gorenflo MP, Zhu X, Xu R | Journal of Alzheimer's disease : JAD | 36846997 | J Alzheimers Dis | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36846997 |
Comorbidity-driven multi-modal subtype analysis in mild cognitive impairment of Alzheimer's disease. | Katabathula S, Davis PB, Xu R | Alzheimer's & dementia : the journal of the Alzheimer's Association | 36166485 | Alzheimers Dement | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36166485 |
Glucagon-like peptide-1 receptor agonists and pancreatic cancer risk: target trial emulation using real-world data. | Wang L, Wang Q, Li L, Kaelber DC, Xu R | Journal of the National Cancer Institute | 39418202 | J Natl Cancer Inst | 2025 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/39418202 |
Comparative analysis of a novel disease phenotype network based on clinical manifestations. | Chen Y, Zhang X, Zhang GQ, Xu R | Journal of biomedical informatics | 25277758 | J Biomed Inform | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25277758 |
Phenome-driven disease genetics prediction toward drug discovery. | Chen Y, Li L, Zhang GQ, Xu R | Bioinformatics (Oxford, England) | 26072493 | Bioinformatics | 2015 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/26072493 |
Network-based gene prediction for Plasmodium falciparum malaria towards genetics-based drug discovery. | Chen Y, Xu R | BMC genomics | 26099491 | BMC Genomics | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26099491 |
Automatic extraction, prioritization and analysis of gut microbial metabolites from biomedical literature. | Wang Q, Xu R | Scientific reports | 32561832 | Sci Rep | 2020 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/32561832 |
Combining phenome-driven drug-target interaction prediction with patients' electronic health records-based clinical corroboration toward drug discovery. | Zhou M, Zheng C, Xu R | Bioinformatics (Oxford, England) | 32657406 | Bioinformatics | 2020 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/32657406 |
A systems biology approach to predict and characterize human gut microbial metabolites in colorectal cancer. | Wang Q, Li L, Xu R | Scientific reports | 29670137 | Sci Rep | 2018 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/29670137 |
Interrogating Patient-level Genomics and Mouse Phenomics towards Understanding Cytokines in Colorectal Cancer Metastasis. | Cai X, Chen Y, Zheng C, Xu R | AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science | 28815134 | AMIA Jt Summits Transl Sci Proc | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28815134 |
Sex-Specific Heterogeneity of Mild Cognitive Impairment Identified Based on Multi-Modal Data Analysis. | Katabathula S, Davis PB, Xu R, Alzheimer’s Disease Neuroimaging Initiative | Journal of Alzheimer's disease : JAD | 36404544 | J Alzheimers Dis | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36404544 |
A knowledge graph-based disease-gene prediction system using multi-relational graph convolution networks. | Gao Z, Pan Y, Ding P, Xu R | AMIA ... Annual Symposium proceedings. AMIA Symposium | 37128437 | AMIA Annu Symp Proc | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/37128437 |
Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization. | Wang Q, Davis PB, Qi X, Chen SG, Gurney ME, Perry G, Doraiswamy PM, Xu R | Alzheimer's research & therapy | 34670619 | Alzheimers Res Ther | 2021 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/34670619 |
Predict Alzheimer's disease using hippocampus MRI data: a lightweight 3D deep convolutional network model with visual and global shape representations. | Katabathula S, Wang Q, Xu R | Alzheimer's research & therapy | 34030743 | Alzheimers Res Ther | 2021 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/34030743 |
DenseCNN: A Densely Connected CNN Model for Alzheimer's Disease Classification Based on Hippocampus MRI Data. | Wang Q, Li Y, Zheng C, Xu R | AMIA ... Annual Symposium proceedings. AMIA Symposium | 33936504 | AMIA Annu Symp Proc | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33936504 |
COVID-19 risk and outcomes in patients with substance use disorders: analyses from electronic health records in the United States. | Wang QQ, Kaelber DC, Xu R, Volkow ND | Molecular psychiatry | 32929211 | Mol Psychiatry | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32929211 |
Data-driven multiple-level analysis of gut-microbiome-immune-joint interactions in rheumatoid arthritis. | Wang Q, Xu R | BMC genomics | 30744546 | BMC Genomics | 2019 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/30744546 |
A semi-supervised approach to extract pharmacogenomics-specific drug-gene pairs from biomedical literature for personalized medicine. | Xu R, Wang Q | Journal of biomedical informatics | 23570835 | J Biomed Inform | 2013 Aug | https://www.ncbi.nlm.nih.gov/pubmed/23570835 |
An iterative searching and ranking algorithm for prioritising pharmacogenomics genes. | Xu R, Wang Q | International journal of computational biology and drug design | 23428471 | Int J Comput Biol Drug Des | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23428471 |
Automatic signal extraction, prioritizing and filtering approaches in detecting post-marketing cardiovascular events associated with targeted cancer drugs from the FDA Adverse Event Reporting System (FAERS). | Xu R, Wang Q | Journal of biomedical informatics | 24177320 | J Biomed Inform | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24177320 |
Towards understanding brain-gut-microbiome connections in Alzheimer's disease. | Xu R, Wang Q | BMC systems biology | 27585440 | BMC Syst Biol | 2016 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/27585440 |
The Alzheimer's comorbidity phenome: mining from a large patient database and phenome-driven genetics prediction. | Zheng C, Xu R | JAMIA open | 30944912 | JAMIA Open | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30944912 |
Molecular subtyping of Alzheimer's disease with consensus non-negative matrix factorization. | Zheng C, Xu R | PloS one | 34014928 | PLoS One | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34014928 |
Large-scale mining disease comorbidity relationships from post-market drug adverse events surveillance data. | Zheng C, Xu R | BMC bioinformatics | 30591027 | BMC Bioinformatics | 2018 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/30591027 |
Drug repositioning for prostate cancer: using a data-driven approach to gain new insights. | Wang Q, Xu R | AMIA ... Annual Symposium proceedings. AMIA Symposium | 29854243 | AMIA Annu Symp Proc | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29854243 |
Towards precision medicine-based therapies for glioblastoma: interrogating human disease genomics and mouse phenotypes. | Chen Y, Gao Z, Wang B, Xu R | BMC genomics | 27557118 | BMC Genomics | 2016 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/27557118 |
Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. | Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, Chan ER, Wang Q, Xu R, Flanagan ME, Pieper AA, Qi X | Science advances | 33277246 | Sci Adv | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33277246 |
An iterative approach to detect pleiotropy and perform Mendelian Randomization analysis using GWAS summary statistics. | Zhu X, Li X, Xu R, Wang T | Bioinformatics (Oxford, England) | 33226062 | Bioinformatics | 2021 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/33226062 |
A genomics-based systems approach towards drug repositioning for rheumatoid arthritis. | Xu R, Wang Q | BMC genomics | 27557330 | BMC Genomics | 2016 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/27557330 |
Predicting cancer origins with a DNA methylation-based deep neural network model. | Zheng C, Xu R | PloS one | 32384093 | PLoS One | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32384093 |
Association of COVID-19 with Risk and Progression of Alzheimer's Disease: Non-Overlapping Two-Sample Mendelian Randomization Analysis of 2.6 Million Subjects. | Ding P, Gurney M, Perry G, Xu R | Journal of Alzheimer's disease : JAD | 38007657 | J Alzheimers Dis | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/38007657 |
Association of semaglutide with risk of suicidal ideation in a real-world cohort. | Wang W, Volkow ND, Berger NA, Davis PB, Kaelber DC, Xu R | Nature medicine | 38182782 | Nat Med | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/38182782 |
Causal association of COVID-19 with brain structure changes: Findings from a non-overlapping 2-sample Mendelian randomization study. | Ding P, Xu R | Journal of the neurological sciences | 37925898 | J Neurol Sci | 2023 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/37925898 |
Current trends in biomarker discovery and analysis tools for traumatic brain injury. | Martinez BI, Stabenfeldt SE | Journal of biological engineering | 30828380 | J Biol Eng | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30828380 |
Exploiting Phage Display for Development of Novel Cellular Targeting Strategies. | Marsh W, Witten A, Stabenfeldt SE | Methods in molecular biology (Clifton, N.J.) | 30051426 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30051426 |
pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma. | Householder KT, DiPerna DM, Chung EP, Luning AR, Nguyen DT, Stabenfeldt SE, Mehta S, Sirianni RW | Colloids and surfaces. B, Biointerfaces | 29533842 | Colloids Surf B Biointerfaces | 2018 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/29533842 |
Uncovering temporospatial sensitive TBI targeting strategies via in vivo phage display. | Martinez BI, Mousa GA, Fleck K, MacCulloch T, Diehnelt CW, Stephanopoulos N, Stabenfeldt SE | Science advances | 35867794 | Sci Adv | 2022 Jul 22 | https://www.ncbi.nlm.nih.gov/pubmed/35867794 |
Tailoring sub-micron PLGA particle release profiles via centrifugal fractioning. | Dutta D, Salifu M, Sirianni RW, Stabenfeldt SE | Journal of biomedical materials research. Part A | 26517011 | J Biomed Mater Res A | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26517011 |
Sex-Dependent Macromolecule and Nanoparticle Delivery in Experimental Brain Injury. | Bharadwaj VN, Copeland C, Mathew E, Newbern J, Anderson TR, Lifshitz J, Kodibagkar VD, Stabenfeldt SE | Tissue engineering. Part A | 32697674 | Tissue Eng Part A | 2020 Jul | https://www.ncbi.nlm.nih.gov/pubmed/32697674 |
Stromal Cell-Derived Factor-1a Autocrine/Paracrine Signaling Contributes to Spatiotemporal Gradients in the Brain. | Hickey KN, Grassi SM, Caplan MR, Stabenfeldt SE | Cellular and molecular bioengineering | 33643467 | Cell Mol Bioeng | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33643467 |
Endogenous repair signaling after brain injury and complementary bioengineering approaches to enhance neural regeneration. | Addington CP, Roussas A, Dutta D, Stabenfeldt SE | Biomarker insights | 25983552 | Biomark Insights | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25983552 |
Siloxane Nanoprobes for Labeling and Dual Modality Functional Imaging of Neural Stem Cells. | Addington CP, Cusick A, Shankar RV, Agarwal S, Stabenfeldt SE, Kodibagkar VD | Annals of biomedical engineering | 26597417 | Ann Biomed Eng | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26597417 |
Enhancing neural stem cell response to SDF-1α gradients through hyaluronic acid-laminin hydrogels. | Addington CP, Heffernan JM, Millar-Haskell CS, Tucker EW, Sirianni RW, Stabenfeldt SE | Biomaterials | 26340314 | Biomaterials | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26340314 |
Using biomaterials to modulate chemotactic signaling for central nervous system repair. | Hickey K, Stabenfeldt SE | Biomedical materials (Bristol, England) | 29411713 | Biomed Mater | 2018 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/29411713 |
Hyaluronic acid-laminin hydrogels increase neural stem cell transplant retention and migratory response to SDF-1α. | Addington CP, Dharmawaj S, Heffernan JM, Sirianni RW, Stabenfeldt SE | Matrix biology : journal of the International Society for Matrix Biology | 27645115 | Matrix Biol | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27645115 |
Hyaluronic Acid Biomaterials for Central Nervous System Regenerative Medicine. | Jensen G, Holloway JL, Stabenfeldt SE | Cells | 32957463 | Cells | 2020 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/32957463 |
In Vivo Phage Display as a Biomarker Discovery Tool for the Complex Neural Injury Microenvironment. | Martinez BI, Stabenfeldt SE | Current protocols | 33625787 | Curr Protoc | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33625787 |
Spatiotemporal presentation of exogenous SDF-1 with PLGA nanoparticles modulates SDF-1/CXCR4 signaling axis in the rodent cortex. | Dutta D, Hickey K, Salifu M, Fauer C, Willingham C, Stabenfeldt SE | Biomaterials science | 28703822 | Biomater Sci | 2017 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/28703822 |
Blood-brainbarrier disruption dictates nanoparticle accumulation following experimental brain injury. | Bharadwaj VN, Rowe RK, Harrison J, Wu C, Anderson TR, Lifshitz J, Adelson PD, Kodibagkar VD, Stabenfeldt SE | Nanomedicine : nanotechnology, biology, and medicine | 29933022 | Nanomedicine | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29933022 |
Leveraging the Dynamic Blood-Brain Barrier for Central Nervous System Nanoparticle-based Drug Delivery Applications. | Copeland C, Stabenfeldt SE | Current opinion in biomedical engineering | 32432210 | Curr Opin Biomed Eng | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32432210 |
Temporal assessment of nanoparticle accumulation after experimental brain injury: Effect of particle size. | Bharadwaj VN, Lifshitz J, Adelson PD, Kodibagkar VD, Stabenfeldt SE | Scientific reports | 27444615 | Sci Rep | 2016 Jul 22 | https://www.ncbi.nlm.nih.gov/pubmed/27444615 |
Nanoparticle-Based Therapeutics for Brain Injury. | Bharadwaj VN, Nguyen DT, Kodibagkar VD, Stabenfeldt SE | Advanced healthcare materials | 29034608 | Adv Healthc Mater | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29034608 |
Tunable delayed controlled release profile from layered polymeric microparticles. | Dutta D, Fauer C, Hickey K, Salifu M, Stabenfeldt SE | Journal of materials chemistry. B | 28652916 | J Mater Chem B | 2017 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/28652916 |
Biomimetic Strategies To Treat Traumatic Brain Injury by Leveraging Fibrinogen. | Brown AC, Lavik E, Stabenfeldt SE | Bioconjugate chemistry | 31246419 | Bioconjug Chem | 2019 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/31246419 |
Tunable Controlled Release of Bioactive SDF-1α via Protein Specific Interactions within Fibrin/Nanoparticle Composites. | Dutta D, Fauer C, Mulleneux HL, Stabenfeldt SE | Journal of materials chemistry. B | 26660666 | J Mater Chem B | 2015 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/26660666 |
GdDO3NI Enhanced Magnetic Resonance Imaging Allows Imaging of Hypoxia After Brain Injury. | Moghadas B, Bharadwaj VN, Tobey JP, Tian Y, Stabenfeldt SE, Kodibagkar VD | Journal of magnetic resonance imaging : JMRI | 34499791 | J Magn Reson Imaging | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/34499791 |
Platelet-like particles reduce coagulopathy-related and neuroinflammatory pathologies post-experimental traumatic brain injury. | Todd J, Bharadwaj VN, Nellenbach K, Nandi S, Mihalko E, Copeland C, Brown AC, Stabenfeldt SE | Journal of biomedical materials research. Part B, Applied biomaterials | 34117693 | J Biomed Mater Res B Appl Biomater | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34117693 |
Enriching s(4) U-RNA Using Methane Thiosulfonate (MTS) Chemistry. | Duffy EE, Simon MD | Current protocols in chemical biology | 27925666 | Curr Protoc Chem Biol | 2016 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/27925666 |
The Properties of Long Noncoding RNAs That Regulate Chromatin. | Rutenberg-Schoenberg M, Sexton AN, Simon MD | Annual review of genomics and human genetics | 27147088 | Annu Rev Genomics Hum Genet | 2016 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/27147088 |
Interpreting Reverse Transcriptase Termination and Mutation Events for Greater Insight into the Chemical Probing of RNA. | Sexton AN, Wang PY, Rutenberg-Schoenberg M, Simon MD | Biochemistry | 28820243 | Biochemistry | 2017 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/28820243 |
Discovery of cellular substrates of human RNA-decapping enzyme DCP2 using a stapled bicyclic peptide inhibitor. | Luo Y, Schofield JA, Na Z, Hann T, Simon MD, Slavoff SA | Cell chemical biology | 33357462 | Cell Chem Biol | 2021 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/33357462 |
Probing Xist RNA Structure in Cells Using Targeted Structure-Seq. | Fang R, Moss WN, Rutenberg-Schoenberg M, Simon MD | PLoS genetics | 26646615 | PLoS Genet | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26646615 |
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-Thioguanosine. | Kiefer L, Schofield JA, Simon MD | Journal of the American Chemical Society | 30353734 | J Am Chem Soc | 2018 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/30353734 |
Carbodiimide reagents for the chemical probing of RNA structure in cells. | Wang PY, Sexton AN, Culligan WJ, Simon MD | RNA (New York, N.Y.) | 30389828 | RNA | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30389828 |
Stella's Role in Oocyte DNA Methylation Suggests Additional Activities of DNMT1. | Kiefer L, Simon MD | Biochemistry | 30920202 | Biochemistry | 2019 Apr 9 | https://www.ncbi.nlm.nih.gov/pubmed/30920202 |
Internally controlled RNA sequencing comparisons using nucleoside recoding chemistry. | Courvan MCS, Niederer RO, Vock IW, Kiefer L, Gilbert WV, Simon MD | Nucleic acids research | 36018791 | Nucleic Acids Res | 2022 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/36018791 |
Tracking Distinct RNA Populations Using Efficient and Reversible Covalent Chemistry. | Duffy EE, Rutenberg-Schoenberg M, Stark CD, Kitchen RR, Gerstein MB, Simon MD | Molecular cell | 26340425 | Mol Cell | 2015 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/26340425 |
Insight into lncRNA biology using hybridization capture analyses. | Simon MD | Biochimica et biophysica acta | 26381323 | Biochim Biophys Acta | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/26381323 |
Global Profiling of Cellular Substrates of Human Dcp2. | Luo Y, Schofield JA, Simon MD, Slavoff SA | Biochemistry | 32365300 | Biochemistry | 2020 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/32365300 |
Catching RNAs on chromatin using hybridization capture methods. | Machyna M, Simon MD | Briefings in functional genomics | 29126220 | Brief Funct Genomics | 2018 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/29126220 |
The NBDY Microprotein Regulates Cellular RNA Decapping. | Na Z, Luo Y, Schofield JA, Smelyansky S, Khitun A, Muthukumar S, Valkov E, Simon MD, Slavoff SA | Biochemistry | 33059440 | Biochemistry | 2020 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/33059440 |
STL-seq reveals pause-release and termination kinetics for promoter-proximal paused RNA polymerase II transcripts. | Zimmer JT, Rosa-Mercado NA, Canzio D, Steitz JA, Simon MD | Molecular cell | 34520723 | Mol Cell | 2021 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/34520723 |
Acetyl-methyllysine marks chromatin at active transcription start sites. | Lu-Culligan WJ, Connor LJ, Xie Y, Ekundayo BE, Rose BT, Machyna M, Pintado-Urbanc AP, Zimmer JT, Vock IW, Bhanu NV, King MC, Garcia BA, Bleichert F, Simon MD | Nature | 37731000 | Nature | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37731000 |
Solid phase chemistry to covalently and reversibly capture thiolated RNA. | Duffy EE, Canzio D, Maniatis T, Simon MD | Nucleic acids research | 29986098 | Nucleic Acids Res | 2018 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/29986098 |
Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice. | Canzio D, Nwakeze CL, Horta A, Rajkumar SM, Coffey EL, Duffy EE, Duffié R, Monahan K, O'Keeffe S, Simon MD, Lomvardas S, Maniatis T | Cell | 30955885 | Cell | 2019 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/30955885 |
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding. | Schofield JA, Duffy EE, Kiefer L, Sullivan MC, Simon MD | Nature methods | 29355846 | Nat Methods | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29355846 |
m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways. | Li HB, Tong J, Zhu S, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z, Flavell RA | Nature | 28792938 | Nature | 2017 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/28792938 |
Gaining insight into transcriptome-wide RNA population dynamics through the chemistry of 4-thiouridine. | Duffy EE, Schofield JA, Simon MD | Wiley interdisciplinary reviews. RNA | 30370679 | Wiley Interdiscip Rev RNA | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30370679 |
Enhanced nucleotide chemistry and toehold nanotechnology reveals lncRNA spreading on chromatin. | Machyna M, Kiefer L, Simon MD | Nature structural & molecular biology | 32157249 | Nat Struct Mol Biol | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32157249 |
Cell chirality: emergence of asymmetry from cell culture. | Wan LQ, Chin AS, Worley KE, Ray P | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 27821525 | Philos Trans R Soc Lond B Biol Sci | 2016 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/27821525 |
Multiaxial Polarity Determines Individual Cellular and Nuclear Chirality. | Raymond MJ Jr, Ray P, Kaur G, Fredericks M, Singh AV, Wan LQ | Cellular and molecular bioengineering | 28360944 | Cell Mol Bioeng | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/28360944 |
Helical vasculogenesis driven by cell chirality. | Zhang H, Rahman T, Lu S, Adam AP, Wan LQ | Science advances | 38381835 | Sci Adv | 2024 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/38381835 |
Cell chirality regulates intercellular junctions and endothelial permeability. | Fan J, Ray P, Lu YW, Kaur G, Schwarz JJ, Wan LQ | Science advances | 30397640 | Sci Adv | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30397640 |
Epithelial Cell Chirality Revealed by Three-Dimensional Spontaneous Rotation. | Chin AS, Worley KE, Ray P, Kaur G, Fan J, Wan LQ | Proceedings of the National Academy of Sciences of the United States of America | 30429314 | Proc Natl Acad Sci U S A | 2018 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/30429314 |
Cell jamming regulates epithelial chiral morphogenesis. | Rahman T, Peters F, Wan LQ | Journal of biomechanics | 36641827 | J Biomech | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36641827 |
Cell Chirality as a Novel Measure for Cytotoxicity. | Zhang H, Wan LQ | Advanced biology | 34796704 | Adv Biol (Weinh) | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34796704 |
Cellular and Nuclear Alignment Analysis for Determining Epithelial Cell Chirality. | Raymond MJ Jr, Ray P, Kaur G, Singh AV, Wan LQ | Annals of biomedical engineering | 26294010 | Ann Biomed Eng | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26294010 |
Effects of Alzheimer's Disease-Related Proteins on the Chirality of Brain Endothelial Cells. | Zhang H, Fan J, Zhao Z, Wang C, Wan LQ | Cellular and molecular bioengineering | 34109002 | Cell Mol Bioeng | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34109002 |
The Actin Crosslinker Fascin Regulates Cell Chirality. | Zhang H, Fan J, Maclin JMA, Wan LQ | Advanced biology | 36658789 | Adv Biol (Weinh) | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/36658789 |
A Micropatterning Assay for Measuring Cell Chirality. | Zhang H, Ronaldson-Bouchard K, Vunjak-Novakovic G, Wan LQ | Journal of visualized experiments : JoVE | 35343954 | J Vis Exp | 2022 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/35343954 |
Lineage-Specific Chiral Biases of Human Embryonic Stem Cells during Differentiation. | Worley KE, Chin AS, Wan LQ | Stem cells international | 30627170 | Stem Cells Int | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30627170 |
Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping. | Ray P, Chin AS, Worley KE, Fan J, Kaur G, Wu M, Wan LQ | Proceedings of the National Academy of Sciences of the United States of America | 30459275 | Proc Natl Acad Sci U S A | 2018 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/30459275 |
In Vitro Microscale Models for Embryogenesis. | Rico-Varela J, Ho D, Wan LQ | Advanced biosystems | 30533517 | Adv Biosyst | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30533517 |
Teratogen screening with human pluripotent stem cells. | Worley KE, Rico-Varela J, Ho D, Wan LQ | Integrative biology : quantitative biosciences from nano to macro | 30095839 | Integr Biol (Camb) | 2018 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/30095839 |
Cell organelle-based analysis of cell chirality. | Fan J, Zhang H, Rahman T, Stanton DN, Wan LQ | Communicative & integrative biology | 31143366 | Commun Integr Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31143366 |
Cell chirality in cardiovascular development and disease. | Rahman T, Zhang H, Fan J, Wan LQ | APL bioengineering | 32903894 | APL Bioeng | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32903894 |
Evaluation of candidate spermatogonial markers ID4 and GPR125 in testes of adult human cadaveric organ donors. | Sachs C, Robinson BD, Andres Martin L, Webster T, Gilbert M, Lo HY, Rafii S, Ng CK, Seandel M | Andrology | 24902969 | Andrology | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24902969 |
Loss of tyrosine kinase receptor Ephb2 impairs proliferation and stem cell activity of spermatogonia in culture†. | N'Tumba-Byn T, Yamada M, Seandel M | Biology of reproduction | 31836902 | Biol Reprod | 2020 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/31836902 |
Male germ cells support long-term propagation of Zika virus. | Robinson CL, Chong ACN, Ashbrook AW, Jeng G, Jin J, Chen H, Tang EI, Martin LA, Kim RS, Kenyon RM, Do E, Luna JM, Saeed M, Zeltser L, Ralph H, Dudley VL, Goldstein M, Rice CM, Cheng CY, Seandel M, Chen S | Nature communications | 29844387 | Nat Commun | 2018 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/29844387 |
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells. | Liu Y, Giannopoulou EG, Wen D, Falciatori I, Elemento O, Allis CD, Rafii S, Seandel M | Nature communications | 27117588 | Nat Commun | 2016 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/27117588 |
Enhanced fitness of adult spermatogonial stem cells bearing a paternal age-associated FGFR2 mutation. | Martin LA, Assif N, Gilbert M, Wijewarnasuriya D, Seandel M | Stem cell reports | 25254335 | Stem Cell Reports | 2014 Aug 12 | https://www.ncbi.nlm.nih.gov/pubmed/25254335 |
Functional robustness of adult spermatogonial stem cells after induction of hyperactive Hras. | Yamada M, Cai W, Martin LA, N'Tumba-Byn T, Seandel M | PLoS genetics | 31050682 | PLoS Genet | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/31050682 |
Faithful Artificial Chromosome Propagation Using Spermatogonial Stem Cells. | Yamada M, Seandel M | Trends in genetics : TIG | 29107344 | Trends Genet | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29107344 |
Spermatogonial Stem Cells: Implications for Genetic Disorders and Prevention. | Yamada M, De Chiara L, Seandel M | Stem cells and development | 27596369 | Stem Cells Dev | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27596369 |
Fabrication of 3-D Reconstituted Organoid Arrays by DNA-Programmed Assembly of Cells (DPAC). | Todhunter ME, Weber RJ, Farlow J, Jee NY, Cerchiari AE, Gartner ZJ | Current protocols in chemical biology | 27622567 | Curr Protoc Chem Biol | 2016 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/27622567 |
Unraveling cell-to-cell signaling networks with chemical biology. | Gartner ZJ, Prescher JA, Lavis LD | Nature chemical biology | 28514428 | Nat Chem Biol | 2017 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/28514428 |
Non-autonomous cell proliferation in the mammary gland and cancer. | Weber RJ, Desai TA, Gartner ZJ | Current opinion in cell biology | 28314237 | Curr Opin Cell Biol | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/28314237 |
Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities. | Chen S, Bremer AW, Scheideler OJ, Na YS, Todhunter ME, Hsiao S, Bomdica PR, Maharbiz MM, Gartner ZJ, Schaffer DV | Nature communications | 26754526 | Nat Commun | 2016 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/26754526 |
Production and targeting of monovalent quantum dots. | Seo D, Farlow J, Southard K, Jun YW, Gartner ZJ | Journal of visualized experiments : JoVE | 25407345 | J Vis Exp | 2014 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/25407345 |
MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices. | McGinnis CS, Patterson DM, Winkler J, Conrad DN, Hein MY, Srivastava V, Hu JL, Murrow LM, Weissman JS, Werb Z, Chow ED, Gartner ZJ | Nature methods | 31209384 | Nat Methods | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31209384 |
Compact and modular multicolour fluorescence detector for droplet microfluidics. | Cole RH, de Lange N, Gartner ZJ, Abate AR | Lab on a chip | 26032595 | Lab Chip | 2015 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/26032595 |
Coupling between apical tension and basal adhesion allow epithelia to collectively sense and respond to substrate topography over long distances. | Broaders KE, Cerchiari AE, Gartner ZJ | Integrative biology : quantitative biosciences from nano to macro | 26507156 | Integr Biol (Camb) | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26507156 |
Mysteries in a Minimal Genome. | Coyle M, Hu J, Gartner Z | ACS central science | 27280161 | ACS Cent Sci | 2016 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/27280161 |
Printed droplet microfluidics for on demand dispensing of picoliter droplets and cells. | Cole RH, Tang SY, Siltanen CA, Shahi P, Zhang JQ, Poust S, Gartner ZJ, Abate AR | Proceedings of the National Academy of Sciences of the United States of America | 28760972 | Proc Natl Acad Sci U S A | 2017 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/28760972 |
Quanti.us: a tool for rapid, flexible, crowd-based annotation of images. | Hughes AJ, Mornin JD, Biswas SK, Beck LE, Bauer DP, Raj A, Bianco S, Gartner ZJ | Nature methods | 30065368 | Nat Methods | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30065368 |
Expanding the boundaries of synthetic development. | Martyn I, Gartner ZJ | Developmental biology | 33587913 | Dev Biol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33587913 |
Programming the Self-Organization of Endothelial Cells into Perfusable Microvasculature. | Cabral KA, Srivastava V, Graham AJ, Coyle MC, Stashko C, Weaver V, Gartner ZJ | Tissue engineering. Part A | 36181350 | Tissue Eng Part A | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36181350 |
Formation of spatially and geometrically controlled three-dimensional tissues in soft gels by sacrificial micromolding. | Cerchiari A, Garbe JC, Todhunter ME, Jee NY, Pinney JR, LaBarge MA, Desai TA, Gartner ZJ | Tissue engineering. Part C, Methods | 25351430 | Tissue Eng Part C Methods | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25351430 |
Dissecting the stem cell niche with organoid models: an engineering-based approach. | Murrow LM, Weber RJ, Gartner ZJ | Development (Cambridge, England) | 28292846 | Development | 2017 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/28292846 |
Phosphorylated EGFR Dimers Are Not Sufficient to Activate Ras. | Liang SI, van Lengerich B, Eichel K, Cha M, Patterson DM, Yoon TY, von Zastrow M, Jura N, Gartner ZJ | Cell reports | 29514089 | Cell Rep | 2018 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/29514089 |
Characterizing cellular mechanical phenotypes with mechano-node-pore sensing. | Kim J, Han S, Lei A, Miyano M, Bloom J, Srivastava V, Stampfer MM, Gartner ZJ, LaBarge MA, Sohn LL | Microsystems & nanoengineering | 29780657 | Microsyst Nanoeng | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29780657 |
A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time. | Seo D, Southard KM, Kim JW, Lee HJ, Farlow J, Lee JU, Litt DB, Haas T, Alivisatos AP, Cheon J, Gartner ZJ, Jun YW | Cell | 28622515 | Cell | 2017 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/28622515 |
Efficient targeting of fatty-acid modified oligonucleotides to live cell membranes through stepwise assembly. | Weber RJ, Liang SI, Selden NS, Desai TA, Gartner ZJ | Biomacromolecules | 25325667 | Biomacromolecules | 2014 Dec 8 | https://www.ncbi.nlm.nih.gov/pubmed/25325667 |
Programmed synthesis of three-dimensional tissues. | Todhunter ME, Jee NY, Hughes AJ, Coyle MC, Cerchiari A, Farlow J, Garbe JC, LaBarge MA, Desai TA, Gartner ZJ | Nature methods | 26322836 | Nat Methods | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26322836 |
A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time. | Seo D, Southard KM, Kim JW, Lee HJ, Farlow J, Lee JU, Litt DB, Haas T, Alivisatos AP, Cheon J, Gartner ZJ, Jun YW | Cell | 27180907 | Cell | 2016 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/27180907 |
Engineered Tissue Folding by Mechanical Compaction of the Mesenchyme. | Hughes AJ, Miyazaki H, Coyle MC, Zhang J, Laurie MT, Chu D, Vavrušová Z, Schneider RA, Klein OD, Gartner ZJ | Developmental cell | 29290586 | Dev Cell | 2018 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/29290586 |
DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors. | McGinnis CS, Murrow LM, Gartner ZJ | Cell systems | 30954475 | Cell Syst | 2019 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/30954475 |
Roadmap for the multiscale coupling of biochemical and mechanical signals during development. | Lenne PF, Munro E, Heemskerk I, Warmflash A, Bocanegra-Moreno L, Kishi K, Kicheva A, Long Y, Fruleux A, Boudaoud A, Saunders TE, Caldarelli P, Michaut A, Gros J, Maroudas-Sacks Y, Keren K, Hannezo E, Gartner ZJ, Stormo B, Gladfelter A, Rodrigues A, Shyer A, Minc N, Maître JL, Di Talia S, Khamaisi B, Sprinzak D, Tlili S | Physical biology | 33276350 | Phys Biol | 2021 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/33276350 |
Organoid models for mammary gland dynamics and breast cancer. | Srivastava V, Huycke TR, Phong KT, Gartner ZJ | Current opinion in cell biology | 32535255 | Curr Opin Cell Biol | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32535255 |
Getting the measure of living biomaterials. | Gartner Z, Hughes A | Nature | 31358937 | Nature | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31358937 |
Single-cell mechanogenetics using monovalent magnetoplasmonic nanoparticles. | Kim JW, Seo D, Lee JU, Southard KM, Lim Y, Kim D, Gartner ZJ, Jun YW, Cheon J | Nature protocols | 28817122 | Nat Protoc | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28817122 |
Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia. | Su-Feher L, Rubin AN, Silberberg SN, Catta-Preta R, Lim KJ, Ypsilanti AR, Zdilar I, McGinnis CS, McKinsey GL, Rubino TE Jr, Hawrylycz MJ, Thompson C, Gartner ZJ, Puelles L, Zeng H, Rubenstein JLR, Nord AS | Proceedings of the National Academy of Sciences of the United States of America | 35377797 | Proc Natl Acad Sci U S A | 2022 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/35377797 |
Effects of cell type and configuration on anabolic and catabolic activity in 3D co-culture of mesenchymal stem cells and nucleus pulposus cells. | Ouyang A, Cerchiari AE, Tang X, Liebenberg E, Alliston T, Gartner ZJ, Lotz JC | Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 27699833 | J Orthop Res | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27699833 |
Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers. | Cole RH, Gartner ZJ, Abate AR | Journal of visualized experiments : JoVE | 27214249 | J Vis Exp | 2016 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/27214249 |
Simple, Affordable, and Modular Patterning of Cells using DNA. | Cabral KA, Patterson DM, Scheideler OJ, Cole R, Abate AR, Schaffer DV, Sohn LL, Gartner ZJ | Journal of visualized experiments : JoVE | 33720126 | J Vis Exp | 2021 Feb 24 | https://www.ncbi.nlm.nih.gov/pubmed/33720126 |
Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution. | Murrow LM, Weber RJ, Caruso JA, McGinnis CS, Phong K, Gascard P, Rabadam G, Borowsky AD, Desai TA, Thomson M, Tlsty T, Gartner ZJ | Cell systems | 35863345 | Cell Syst | 2022 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/35863345 |
A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity. | Cerchiari AE, Garbe JC, Jee NY, Todhunter ME, Broaders KE, Peehl DM, Desai TA, LaBarge MA, Thomson M, Gartner ZJ | Proceedings of the National Academy of Sciences of the United States of America | 25633040 | Proc Natl Acad Sci U S A | 2015 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/25633040 |
Probing the luminal microenvironment of reconstituted epithelial microtissues. | Cerchiari AE, Samy KE, Todhunter ME, Schlesinger E, Henise J, Rieken C, Gartner ZJ, Desai TA | Scientific reports | 27619235 | Sci Rep | 2016 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/27619235 |
Opportunities for organoids as new models of aging. | Hu JL, Todhunter ME, LaBarge MA, Gartner ZJ | The Journal of cell biology | 29263081 | J Cell Biol | 2018 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/29263081 |
Predicting the Population Health Impacts of Community Interventions: The Case of Alcohol Outlets and Binge Drinking. | Ahern J, Colson KE, Margerson-Zilko C, Hubbard A, Galea S | American journal of public health | 27631757 | Am J Public Health | 2016 Nov | https://www.ncbi.nlm.nih.gov/pubmed/27631757 |
Nonfatal Assault Injury Trends in California, 2005 to 2015. | Rowe CL, Matthay EC, Ahern J | Journal of interpersonal violence | 30819036 | J Interpers Violence | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30819036 |
Acute Changes in Community Violence and Increases in Hospital Visits and Deaths From Stress-responsive Diseases. | Ahern J, Matthay EC, Goin DE, Farkas K, Rudolph KE | Epidemiology (Cambridge, Mass.) | 29889688 | Epidemiology | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/29889688 |
Impact of drought on crime in California: A synthetic control approach. | Goin DE, Rudolph KE, Ahern J | PloS one | 28977002 | PLoS One | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28977002 |
Conducting density-sampled case-control studies using survey data with complex sampling designs: A simulation study. | Li CX, Matthay EC, Rowe C, Bradshaw PT, Ahern J | Annals of epidemiology | 34216780 | Ann Epidemiol | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34216780 |
Changing Patterns in Rates and Means of Suicide in California, 2005 to 2013. | Matthay EC, Galin J, Ahern J | American journal of public health | 28177819 | Am J Public Health | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28177819 |
Associations of firearm dealer openings with firearm self-harm deaths and injuries: A differences-in-differences analysis. | Matthay EC, Farkas K, Goin DE, Rudolph KE, Pear VA, Ahern J | PloS one | 33735181 | PLoS One | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33735181 |
Optimally combining propensity score subclasses. | Rudolph KE, Colson KE, Stuart EA, Ahern J | Statistics in medicine | 27426623 | Stat Med | 2016 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/27426623 |
Spatial Proximity to Incidents of Community Violence Is Associated with Fewer Suicides in Urban California. | Colson KE, Galin J, Ahern J | Journal of urban health : bulletin of the New York Academy of Medicine | 27541632 | J Urban Health | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27541632 |
Mental and substance use disorders among legal intervention injury cases in California, 2005-2014. | Farkas K, Matthay EC, Rudolph KE, Goin DE, Ahern J | Preventive medicine | 30759367 | Prev Med | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30759367 |
The roles of outlet density and norms in alcohol use disorder. | Ahern J, Balzer L, Galea S | Drug and alcohol dependence | 25858787 | Drug Alcohol Depend | 2015 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/25858787 |
Injuries to Children and Adolescents by Law Enforcement: An Analysis of California Emergency Department Visits and Hospitalizations, 2005-2017. | Farkas K, Duarte CD, Ahern J | JAMA pediatrics | 34491288 | JAMA Pediatr | 2022 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/34491288 |
California's Public Safety Realignment Act and prisoner mortality. | Rowe CL, Hubbard A, Ahern J | PloS one | 37115751 | PLoS One | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37115751 |
Firearm Violence Following the Implementation of California's Gun Violence Restraining Order Law. | Pear VA, Wintemute GJ, Jewell NP, Ahern J | JAMA network open | 35380646 | JAMA Netw Open | 2022 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/35380646 |
Assessment of Case Fatality Rates and Overall Prevalence of Firearm Violence in California, 2005-2019. | Brantingham PJ, Tita GE, Jung S, Ahern J | JAMA network open | 35089356 | JAMA Netw Open | 2022 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/35089356 |
Living in Violent Neighbourhoods is Associated with Gestational Weight Gain Outside the Recommended Range. | Galin J, Abrams B, Leonard SA, Matthay EC, Goin DE, Ahern J | Paediatric and perinatal epidemiology | 27921300 | Paediatr Perinat Epidemiol | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27921300 |
Optimizing matching and analysis combinations for estimating causal effects. | Colson KE, Rudolph KE, Zimmerman SC, Goin DE, Stuart EA, Laan Mv, Ahern J | Scientific reports | 26980444 | Sci Rep | 2016 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/26980444 |
California's Mental Health Services Act and Mortality Due to Suicide, Homicide, and Acute Effects of Alcohol: A Synthetic Control Application. | Zimmerman SC, Matthay EC, Rudolph KE, Goin DE, Farkas K, Rowe CL, Ahern J | American journal of epidemiology | 33884408 | Am J Epidemiol | 2021 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/33884408 |
Associations Between Gun Shows and Firearm Deaths and Injuries. | Matthay EC, Galin J, Farkas K, Rudolph K, Wintemute G, Ahern J | Annals of internal medicine | 29971416 | Ann Intern Med | 2018 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/29971416 |
Exposure to Community Homicide During Pregnancy and Adverse Birth Outcomes: A Within-Community Matched Design. | Goin DE, M Gomez A, Farkas K, Zimmerman SC, Matthay EC, Ahern J | Epidemiology (Cambridge, Mass.) | 31180933 | Epidemiology | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31180933 |
Community-Level Risk Factors for Firearm Assault and Homicide: The Role of Local Firearm Dealers and Alcohol Outlets. | Pear VA, Wintemute GJ, Jewell NP, Cerdá M, Ahern J | Epidemiology (Cambridge, Mass.) | 37708491 | Epidemiology | 2023 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/37708491 |
The role of firearm and alcohol availability in firearm suicide: A population-based weighted case-control study. | Pear VA, Wintemute GJ, Jewell NP, Ahern J | Health & place | 36681063 | Health Place | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36681063 |
Addressing population health and health inequalities: the role of fundamental causes. | Cerdá M, Tracy M, Ahern J, Galea S | American journal of public health | 25100428 | Am J Public Health | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/25100428 |
Population Intervention Measures to Connect Research Findings to Policy. | Ahern J | American journal of public health | 27831772 | Am J Public Health | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27831772 |
Firearm and Nonfirearm Violence After Operation Peacemaker Fellowship in Richmond, California, 1996-2016. | Matthay EC, Farkas K, Rudolph KE, Zimmerman S, Barragan M, Goin DE, Ahern J | American journal of public health | 31536413 | Am J Public Health | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31536413 |
In-State and Interstate Associations Between Gun Shows and Firearm Deaths and Injuries: A Quasi-experimental Study. | Matthay EC, Galin J, Rudolph KE, Farkas K, Wintemute GJ, Ahern J | Annals of internal medicine | 29059689 | Ann Intern Med | 2017 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/29059689 |
Racial and ethnic differences in associations of community violence with self-harm: a population-based case-control study. | Matthay EC, Farkas K, Ahern J | Annals of epidemiology | 31072682 | Ann Epidemiol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31072682 |
Occurrence of fatal police violence during pregnancy and hazard of preterm birth in California. | Goin DE, Gomez AM, Farkas K, Duarte C, Karasek D, Chambers BD, Jackson AV, Ahern J | Paediatric and perinatal epidemiology | 33689194 | Paediatr Perinat Epidemiol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33689194 |
Predictors of firearm violence in urban communities: A machine-learning approach. | Goin DE, Rudolph KE, Ahern J | Health & place | 29549755 | Health Place | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29549755 |
Within-community Variation in Violence and Risk of Self-harm in California: A Population-based Case-crossover Study. | Matthay EC, Rudolph KE, Goin DE, Farkas K, Skeem J, Ahern J | Epidemiology (Cambridge, Mass.) | 30720589 | Epidemiology | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30720589 |
Exposure to Community Violence and Self-harm in California: A Multilevel, Population-based, Case-Control Study. | Matthay EC, Farkas K, Skeem J, Ahern J | Epidemiology (Cambridge, Mass.) | 29889134 | Epidemiology | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/29889134 |
Estimating Effects with Rare Outcomes and High Dimensional Covariates: Knowledge is Power. | Balzer L, Ahern J, Galea S, van der Laan M | Epidemiologic methods | 28529839 | Epidemiol Methods | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/28529839 |
Preliminary Experiments with a Unified Controller for a Powered Knee-Ankle Prosthetic Leg Across Walking Speeds. | Quintero D, Villarreal DJ, Gregg RD | Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems | 28392969 | Rep U S | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28392969 |
Unified Phase Variables of Relative Degree Two for Human Locomotion. | Villarreal DJ, Gregg RD | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 28261013 | Annu Int Conf IEEE Eng Med Biol Soc | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28261013 |
Decentralized Feedback Controllers for Exponential Stabilization of Hybrid Periodic Orbits: Application to Robotic Walking. | Hamed KA, Gregg RD | Proceedings of the ... American Control Conference. American Control Conference | 27990059 | Proc Am Control Conf | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27990059 |
Decentralized Passivity-Based Control With a Generalized Energy Storage Function for Robust Biped Locomotion. | Yeatman M, Lv G, Gregg RD | Journal of dynamic systems, measurement, and control | 31666751 | J Dyn Syst Meas Control | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31666751 |
Experimental Implementation of Underactuated Potential Energy Shaping on a Powered Ankle-Foot Orthosis. | Lv G, Zhu H, Elery T, Li L, Gregg RD | IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation | 27390625 | IEEE Int Conf Robot Autom | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27390625 |
Towards Total Energy Shaping Control of Lower-Limb Exoskeletons. | Lv G, Gregg RD | Proceedings of the ... American Control Conference. American Control Conference | 29104363 | Proc Am Control Conf | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/29104363 |
Underactuated Potential Energy Shaping with Contact Constraints: Application to a Powered Knee-Ankle Orthosis. | Lv G, Gregg RD | IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society | 29398885 | IEEE Trans Control Syst Technol | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29398885 |
Stable, Robust Hybrid Zero Dynamics Control of Powered Lower-Limb Prostheses. | Martin AE, Gregg RD | IEEE transactions on automatic control | 29276305 | IEEE Trans Automat Contr | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29276305 |
Real-Time Continuous Gait Phase and Speed Estimation from a Single Sensor. | Quintero D, Lambert DJ, Villarreal DJ, Gregg RD | Control Technology and Applications. Control Technology and Applications | 30148285 | Control Technol Appl | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30148285 |
Modeling the Kinematics of Human Locomotion Over Continuously Varying Speeds and Inclines. | Embry KR, Villarreal DJ, Macaluso RL, Gregg RD | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society | 30403633 | IEEE Trans Neural Syst Rehabil Eng | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30403633 |
A survey of phase variable candidates of human locomotion. | Villarreal DJ, Gregg RD | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 25570873 | Annu Int Conf IEEE Eng Med Biol Soc | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25570873 |
Design and Validation of a Partial-Assist Knee Orthosis with Compact, Backdrivable Actuation. | Zhu H, Nesler C, Divekar N, Ahmad MT, Gregg RD | IEEE ... International Conference on Rehabilitation Robotics : [proceedings] | 31374747 | IEEE Int Conf Rehabil Robot | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31374747 |
Hybrid Nonlinear Disturbance Observer Design for Underactuated Bipedal Robots. | Mohammadi A, Fakoorian S, Horn JC, Simon D, Gregg RD | Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control | 30778276 | Proc IEEE Conf Decis Control | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30778276 |
A Phase Variable Approach for Improved Rhythmic and Non-Rhythmic Control of a Powered Knee-Ankle Prosthesis. | Rezazadeh S, Quintero D, Divekar N, Reznick E, Gray L, Gregg RD | IEEE access : practical innovations, open solutions | 31656719 | IEEE Access | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31656719 |
A Perturbation Mechanism for Investigations of Phase Variables in Human Locomotion. | Villarreal DJ, Quintero D, Gregg RD | ... IEEE International Conference on Robotics and Biomimetics. IEEE International Conference on Robotics and Biomimetics | 27158684 | IEEE ROBIO | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27158684 |
A Robust Parameterization of Human Gait Patterns Across Phase-Shifting Perturbations. | Villarreal DJ, Poonawala HA, Gregg RD | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society | 27187967 | IEEE Trans Neural Syst Rehabil Eng | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/27187967 |
A Control Framework for Anthropomorphic Biped Walking Based on Stabilizing Feedforward Trajectories. | Rezazadeh S, Gregg RD | Proceedings of the ASME Dynamic Systems and Control Conference. ASME Dynamic Systems and Control Conference | 28239504 | Proc ASME Dyn Syst Control Conf | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28239504 |
Design and Benchtop Validation of a Powered Knee-Ankle Prosthesis with High-Torque, Low-Impedance Actuators. | Elery T, Rezazadeh S, Nesler C, Doan J, Zhu H, Gregg RD | IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation | 30598854 | IEEE Int Conf Robot Autom | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/30598854 |
Automatic Tuning of Virtual Constraint-Based Control Algorithms for Powered Knee-Ankle Prostheses. | Kumar S, Mohammadi A, Gans N, Gregg RD | Control Technology and Applications. Control Technology and Applications | 30175324 | Control Technol Appl | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30175324 |
Piecewise and unified phase variables in the control of a powered prosthetic leg. | Villarreal DJ, Quintero D, Gregg RD | IEEE ... International Conference on Rehabilitation Robotics : [proceedings] | 28814020 | IEEE Int Conf Rehabil Robot | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28814020 |
Extremum Seeking Control for Model-Free Auto-Tuning of Powered Prosthetic Legs. | Kumar S, Mohammadi A, Quintero D, Rezazadeh S, Gans N, Gregg RD | IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society | 33041615 | IEEE Trans Control Syst Technol | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33041615 |
Design and Validation of a Powered Knee-Ankle Prosthesis with High-Torque, Low-Impedance Actuators. | Elery T, Rezazadeh S, Nesler C, Gregg RD | IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society | 33299386 | IEEE Trans Robot | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33299386 |
Prosthetic Leg Control in the Nullspace of Human Interaction. | Gregg RD, Martin AE | Proceedings of the ... American Control Conference. American Control Conference | 27746585 | Proc Am Control Conf | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27746585 |
A GENERAL FRAMEWORK FOR MINIMIZING ENERGY CONSUMPTION OF SERIES ELASTIC ACTUATORS WITH REGENERATION. | Bolívar E, Rezazadeh S, Gregg R | Proceedings of the ASME Dynamic Systems and Control Conference. ASME Dynamic Systems and Control Conference | 29170721 | Proc ASME Dyn Syst Control Conf | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29170721 |
Incorporating Human-like Walking Variability in an HZD-Based Bipedal Model. | Martin AE, Gregg RD | IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society | 28082836 | IEEE Trans Robot | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28082836 |
A Unified Parameterization of Human Gait Across Ambulation Modes. | Embry KR, Villarreal DJ, Gregg RD | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 28261005 | Annu Int Conf IEEE Eng Med Biol Soc | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28261005 |
Decentralized Feedback Controllers for Robust Stabilization of Periodic Orbits of Hybrid Systems: Application to Bipedal Walking. | Hamed KA, Gregg RD | IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society | 28959117 | IEEE Trans Control Syst Technol | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28959117 |
A Perturbation Mechanism for Investigations of Phase-Dependent Behavior in Human Locomotion. | Villarreal DJ, Quintero D, Gregg RD | IEEE access : practical innovations, open solutions | 27570719 | IEEE Access | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27570719 |
Hybrid Invariance and Stability of a Feedback Linearizing Controller for Powered Prostheses. | Martin AE, Gregg RD | Proceedings of the ... American Control Conference. American Control Conference | 26604427 | Proc Am Control Conf | 2015 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/26604427 |
Intuitive Clinician Control Interface for a Powered Knee-Ankle Prosthesis: A Case Study. | Quintero D, Reznick E, Lambert DJ, Rezazadeh S, Gray L, Gregg RD | IEEE journal of translational engineering in health and medicine | 30546971 | IEEE J Transl Eng Health Med | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30546971 |
Virtual Constraint Control of a Powered Prosthetic Leg: From Simulation to Experiments with Transfemoral Amputees. | Gregg RD, Lenzi T, Hargrove LJ, Sensinger JW | IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society | 25558185 | IEEE Trans Robot | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25558185 |
Variable Impedance Control of Powered Knee Prostheses Using Human-Inspired Algebraic Curves. | Mohammadi A, Gregg RD | Journal of computational and nonlinear dynamics | 32280314 | J Comput Nonlinear Dyn | 2019 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/32280314 |
Design and Validation of a Torque Dense, Highly Backdrivable Powered Knee-Ankle Orthosis. | Zhu H, Doan J, Stence C, Lv G, Elery T, Gregg R | IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation | 29057142 | IEEE Int Conf Robot Autom | 2017 May-Jun | https://www.ncbi.nlm.nih.gov/pubmed/29057142 |
A Phase Variable Approach to Volitional Control of Powered Knee-Ankle Prostheses. | Rezazadeh S, Quintero D, Divekar N, Gregg RD | Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems | 30746286 | Rep U S | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30746286 |
Design Principles for Compact, Backdrivable Actuation in Partial-Assist Powered Knee Orthoses. | Zhu H, Nesler C, Divekar N, Peddinti V, Gregg RD | IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division | 34916771 | IEEE ASME Trans Mechatron | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34916771 |
Evidence for a time-invariant phase variable in human ankle control. | Gregg RD, Rouse EJ, Hargrove LJ, Sensinger JW | PloS one | 24558485 | PLoS One | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24558485 |
Orthotic Body-Weight Support Through Underactuated Potential Energy Shaping with Contact Constraints. | Lv G, Gregg RD | Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control | 26900254 | Proc IEEE Conf Decis Control | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26900254 |
Unifying the Gait Cycle in the Control of a Powered Prosthetic Leg. | Quintero D, Martin AE, Gregg RD | IEEE ... International Conference on Rehabilitation Robotics : [proceedings] | 26913092 | IEEE Int Conf Rehabil Robot | 2015 Aug | https://www.ncbi.nlm.nih.gov/pubmed/26913092 |
SIMULTANEOUS CONTROL OF AN ANKLE-FOOT PROSTHESIS MODEL USING A VIRTUAL CONSTRAINT. | Nanjangud A, Gregg RD | Proceedings of the ASME Dynamic Systems and Control Conference. ASME Dynamic Systems and Control Conference | 25554734 | Proc ASME Dyn Syst Control Conf | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25554734 |
Characterizing and modeling the joint-level variability in human walking. | Martin AE, Villarreal DJ, Gregg RD | Journal of biomechanics | 27594679 | J Biomech | 2016 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/27594679 |
Minimizing Energy Consumption and Peak Power of Series Elastic Actuators: A Convex Optimization Framework for Elastic Element Design. | Bolívar Nieto EA, Rezazadeh S, Gregg RD 4th | IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division | 31649476 | IEEE ASME Trans Mechatron | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31649476 |
Robust Optimal Design of Energy Efficient Series Elastic Actuators: Application to a Powered Prosthetic Ankle. | Bolivar E, Rezazadeh S, Summers T, Gregg RD | IEEE ... International Conference on Rehabilitation Robotics : [proceedings] | 31374719 | IEEE Int Conf Rehabil Robot | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31374719 |
Removing Phase Variables from Biped Robot Parametric Gaits. | Mohammadi A, Horn J, Gregg RD | Control Technology and Applications. Control Technology and Applications | 30198027 | Control Technol Appl | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30198027 |
On the Design and Control of Highly Backdrivable Lower-Limb Exoskeletons: A Discussion of Past and Ongoing Work. | Lv G, Zhu H, Gregg RD | IEEE control systems | 30598586 | IEEE Control Syst | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30598586 |
Parameterizing Human Locomotion Across Quasi-Random Treadmill Perturbations and Inclines. | Macaluso R, Embry K, Villarreal DJ, Gregg RD | IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society | 33556013 | IEEE Trans Neural Syst Rehabil Eng | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33556013 |
Toward Unified Control of a Powered Prosthetic Leg: A Simulation Study. | Quintero D, Martin AE, Gregg RD | IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society | 29403259 | IEEE Trans Control Syst Technol | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29403259 |
Passivity-Based Control with a Generalized Energy Storage Function for Robust Walking of Biped Robots. | Yeatman MR, Lv G, Gregg RD | Proceedings of the ... American Control Conference. American Control Conference | 30220783 | Proc Am Control Conf | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30220783 |
Continuous-Phase Control of a Powered Knee-Ankle Prosthesis: Amputee Experiments Across Speeds and Inclines. | Quintero D, Villarreal DJ, Lambert DJ, Kapp S, Gregg RD | IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society | 30008623 | IEEE Trans Robot | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30008623 |
A Haptic Feedback System for Phase-Based Sensory Restoration in Above-Knee Prosthetic Leg Users. | Plauche A, Villarreal D, Gregg RD | IEEE transactions on haptics | 27323375 | IEEE Trans Haptics | 2016 Jul-Sep | https://www.ncbi.nlm.nih.gov/pubmed/27323375 |
HUMAN-INSPIRED ALGEBRAIC CURVES FOR WEARABLE ROBOT CONTROL. | Mohammadi A, Gregg RD | Proceedings of the ASME Dynamic Systems and Control Conference. ASME Dynamic Systems and Control Conference | 30906619 | Proc ASME Dyn Syst Control Conf | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30906619 |
Engineering immunity in the mucosal niche against sexually transmitted infections. | Ramanathan R, Woodrow K | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 26153141 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2016 Jan-Feb | https://www.ncbi.nlm.nih.gov/pubmed/26153141 |
Effect of Mucosal Cytokine Administration on Selective Expansion of Vaginal Dendritic Cells to Support Nanoparticle Transport. | Ramanathan R, Park J, Hughes SM, Lykins WR, Bennett HR, Hladik F, Woodrow KA | American journal of reproductive immunology (New York, N.Y. : 1989) | 26118309 | Am J Reprod Immunol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26118309 |
Microneedle-Mediated Vaccine Delivery to the Oral Mucosa. | Creighton RL, Woodrow KA | Advanced healthcare materials | 30537400 | Adv Healthc Mater | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30537400 |
Role of heterogeneous cell population on modulation of dendritic cell phenotype and activation of CD8 T cells for use in cell-based immunotherapies. | Frizzell H, Park J, Comandante Lou N, Woodrow KA | Cellular immunology | 27793335 | Cell Immunol | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27793335 |
Chitosan enhances nanoparticle delivery from the reproductive tract to target draining lymphoid organs. | Park J, Ramanathan R, Pham L, Woodrow KA | Nanomedicine : nanotechnology, biology, and medicine | 28435136 | Nanomedicine | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28435136 |
Sustained Intracellular Raltegravir Depots Generated with Prodrugs Designed for Nanoparticle Delivery. | Creighton RL, Suydam IT, Ebner ME, Afunugo WE, Bever AM, Cao S, Jiang Y, Woodrow KA | ACS biomaterials science & engineering | 33117884 | ACS Biomater Sci Eng | 2019 Aug 12 | https://www.ncbi.nlm.nih.gov/pubmed/33117884 |
Protein-loaded emulsion electrospun fibers optimized for bioactivity retention and pH-controlled release for peroral delivery of biologic therapeutics. | Frizzell H, Ohlsen TJ, Woodrow KA | International journal of pharmaceutics | 28941831 | Int J Pharm | 2017 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/28941831 |
Cross-Platform Comparison of Therapeutic Delivery from Multilamellar Lipid-Coated Polymer Nanoparticles. | Golan-Paz S, Frizzell H, Woodrow KA | Macromolecular bioscience | 30589222 | Macromol Biosci | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30589222 |
Biophysical characterization of small molecule antiviral-loaded nanolipogels for HIV-1 chemoprophylaxis and topical mucosal application. | Ramanathan R, Jiang Y, Read B, Golan-Paz S, Woodrow KA | Acta biomaterialia | 26947382 | Acta Biomater | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26947382 |
Rational design of charged peptides that self-assemble into robust nanofibers as immune-functional scaffolds. | Zhang H, Park J, Jiang Y, Woodrow KA | Acta biomaterialia | 28365480 | Acta Biomater | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28365480 |
Vaginal delivery of vaccines. | VanBenschoten HM, Woodrow KA | Advanced drug delivery reviews | 34481031 | Adv Drug Deliv Rev | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34481031 |
Flt3-L enhances trans-epithelial migration and antigen presentation of dendritic cells adoptively transferred to genital mucosa. | Park J, Frizzell H, Zhang H, Cao S, Hughes SM, Hladik F, Koelle DM, Woodrow KA | Journal of controlled release : official journal of the Controlled Release Society | 33035616 | J Control Release | 2021 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/33035616 |
Oral mucosal vaccination using integrated fiber microneedles. | Creighton RL, Faber KA, Tobos CI, Doan MA, Guo T, Woodrow KA | Journal of controlled release : official journal of the Controlled Release Society | 38295993 | J Control Release | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38295993 |
Noninvasive Prediction of Congenital Cytomegalovirus Infection After Maternal Primary Infection. | Rouse DJ, Fette LM, Hughes BL, Saade GR, Dinsmoor MJ, Reddy UM, Pass R, Allard D, Mallett G, Clifton RG, Saccoccio FM, Permar SR, Gyamfi-Bannerman C, Varner MW, Goodnight WH, Tita ATN, Costantine MM, Swamy GK, Heyborne KD, Chien EK, Chauhan SP, El-Sayed YY, Casey BM, Parry S, Simhan HN, Napolitano PG, Macones GA, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network | Obstetrics and gynecology | 35115450 | Obstet Gynecol | 2022 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/35115450 |
Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission. | Bialas KM, Tanaka T, Tran D, Varner V, Cisneros De La Rosa E, Chiuppesi F, Wussow F, Kattenhorn L, Macri S, Kunz EL, Estroff JA, Kirchherr J, Yue Y, Fan Q, Lauck M, O'Connor DH, Hall AH, Xavier A, Diamond DJ, Barry PA, Kaur A, Permar SR | Proceedings of the National Academy of Sciences of the United States of America | 26483473 | Proc Natl Acad Sci U S A | 2015 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/26483473 |
Preventing postnatal cytomegalovirus infection in the preterm infant: should it be done, can it be done, and at what cost? | Wright CJ, Permar SR | The Journal of pediatrics | 25662832 | J Pediatr | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25662832 |
Perinatal cytomegalovirus and varicella zoster virus infections: epidemiology, prevention, and treatment. | Bialas KM, Swamy GK, Permar SR | Clinics in perinatology | 25677997 | Clin Perinatol | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25677997 |
Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques. | Nguyen SM, Antony KM, Dudley DM, Kohn S, Simmons HA, Wolfe B, Salamat MS, Teixeira LBC, Wiepz GJ, Thoong TH, Aliota MT, Weiler AM, Barry GL, Weisgrau KL, Vosler LJ, Mohns MS, Breitbach ME, Stewart LM, Rasheed MN, Newman CM, Graham ME, Wieben OE, Turski PA, Johnson KM, Post J, Hayes JM, Schultz-Darken N, Schotzko ML, Eudailey JA, Permar SR, Rakasz EG, Mohr EL, Capuano S 3rd, Tarantal AF, Osorio JE, O'Connor SL, Friedrich TC, O'Connor DH, Golos TG | PLoS pathogens | 28542585 | PLoS Pathog | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28542585 |
Humoral Immune Correlates for Prevention of Postnatal Cytomegalovirus Acquisition. | Saccoccio FM, Jenks JA, Itell HL, Li SH, Berry M, Pollara J, Casper C, Gantt S, Permar SR | The Journal of infectious diseases | 31107951 | J Infect Dis | 2019 Jul 31 | https://www.ncbi.nlm.nih.gov/pubmed/31107951 |
The Excess Burden of Cytomegalovirus in African American Communities: A Geospatial Analysis. | Lantos PM, Permar SR, Hoffman K, Swamy GK | Open forum infectious diseases | 26716106 | Open Forum Infect Dis | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26716106 |
The March towards a Vaccine for Congenital CMV: Rationale and Models. | Bialas KM, Permar SR | PLoS pathogens | 26866914 | PLoS Pathog | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26866914 |
Postnatal Cytomegalovirus Infection and the Risk for Bronchopulmonary Dysplasia. | Kelly MS, Benjamin DK, Puopolo KM, Laughon MM, Clark RH, Mukhopadhyay S, Benjamin DK Jr, Smith PB, Permar SR | JAMA pediatrics | 26642118 | JAMA Pediatr | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26642118 |
A rhesus macaque model of Asian-lineage Zika virus infection. | Dudley DM, Aliota MT, Mohr EL, Weiler AM, Lehrer-Brey G, Weisgrau KL, Mohns MS, Breitbach ME, Rasheed MN, Newman CM, Gellerup DD, Moncla LH, Post J, Schultz-Darken N, Schotzko ML, Hayes JM, Eudailey JA, Moody MA, Permar SR, O'Connor SL, Rakasz EG, Simmons HA, Capuano S, Golos TG, Osorio JE, Friedrich TC, O'Connor DH | Nature communications | 27352279 | Nat Commun | 2016 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/27352279 |
Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys. | Nelson CS, Cruz DV, Tran D, Bialas KM, Stamper L, Wu H, Gilbert M, Blair R, Alvarez X, Itell H, Chen M, Deshpande A, Chiuppesi F, Wussow F, Diamond DJ, Vandergrift N, Walter MR, Barry PA, Cohen-Wolkowiez M, Koelle K, Kaur A, Permar SR | JCI insight | 28679960 | JCI Insight | 2017 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/28679960 |
Neighborhood Disadvantage is Associated with High Cytomegalovirus Seroprevalence in Pregnancy. | Lantos PM, Hoffman K, Permar SR, Jackson P, Hughes BL, Kind A, Swamy G | Journal of racial and ethnic health disparities | 28840519 | J Racial Ethn Health Disparities | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28840519 |
Geographic and Racial Disparities in Infant Hearing Loss. | Lantos PM, Maradiaga-Panayotti G, Barber X, Raynor E, Tucci D, Hoffman K, Permar SR, Jackson P, Hughes BL, Kind A, Swamy GK | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | 30296906 | Otolaryngol Head Neck Surg | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30296906 |
Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections. | Itell HL, Kaur A, Deere JD, Barry PA, Permar SR | Current opinion in virology | 28888133 | Curr Opin Virol | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28888133 |
Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women. | Martinez DR, Fong Y, Li SH, Yang F, Jennewein MF, Weiner JA, Harrell EA, Mangold JF, Goswami R, Seage GR 3rd, Alter G, Ackerman ME, Peng X, Fouda GG, Permar SR | Cell | 31204101 | Cell | 2019 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/31204101 |
Cytomegalovirus as an immunomodulator across the lifespan. | Semmes EC, Hurst JH, Walsh KM, Permar SR | Current opinion in virology | 32818717 | Curr Opin Virol | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32818717 |
Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission. | Fan Q, Nelson CS, Bialas KM, Chiuppesi F, Amos J, Gurley TC, Marshall DJ, Eudailey J, Heimsath H, Himes J, Deshpande A, Walter MR, Wussow F, Diamond DJ, Barry PA, Moody MA, Kaur A, Permar SR | Clinical and vaccine immunology : CVI | 28298291 | Clin Vaccine Immunol | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28298291 |
Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection. | Moström MJ, Yu S, Tran D, Saccoccio FM, Versoza CJ, Malouli D, Mirza A, Valencia S, Gilbert M, Blair RV, Hansen S, Barry P, Früh K, Jensen JD, Pfeifer SP, Kowalik TF, Permar SR, Kaur A | PLoS pathogens | 37796819 | PLoS Pathog | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37796819 |
Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model. | Otero CE, Barfield R, Scheef E, Nelson CS, Rodgers N, Wang HY, Moström MJ, Manuel TD, Sass J, Schmidt K, Taher H, Papen C, Sprehe L, Kendall S, Davalos A, Barry PA, Früh K, Pollara J, Malouli D, Chan C, Kaur A, Permar SR | bioRxiv : the preprint server for biology | 37131785 | bioRxiv | 2023 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/37131785 |
Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model. | Otero CE, Barfield R, Scheef E, Nelson CS, Rodgers N, Wang HY, Moström MJ, Manuel TD, Sass J, Schmidt K, Taher H, Papen C, Sprehe L, Kendall S, Davalos A, Barry PA, Früh K, Pollara J, Malouli D, Chan C, Kaur A, Permar SR | PLoS pathogens | 37871009 | PLoS Pathog | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37871009 |
Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity. | Otero CE, Petkova S, Ebermann M, Taher H, John N, Hoffmann K, Davalos A, Moström MJ, Gilbride RM, Papen CR, Barber-Axthelm A, Scheef EA, Barfield R, Sprehe LM, Kendall S, Manuel TD, Beechwood T, Nguyen LK, Vande Burgt NH, Chan C, Denton M, Streblow ZJ, Streblow DN, Tarantal AF, Hansen SG, Kaur A, Permar S, Früh K, Hengel H, Malouli D, Kolb P | Nature communications | 39885150 | Nat Commun | 2025 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/39885150 |
In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome. | Taher H, Mahyari E, Kreklywich C, Uebelhoer LS, McArdle MR, Moström MJ, Bhusari A, Nekorchuk M, E X, Whitmer T, Scheef EA, Sprehe LM, Roberts DL, Hughes CM, Jackson KA, Selseth AN, Ventura AB, Cleveland-Rubeor HC, Yue Y, Schmidt KA, Shao J, Edlefsen PT, Smedley J, Kowalik TF, Stanton RJ, Axthelm MK, Estes JD, Hansen SG, Kaur A, Barry PA, Bimber BN, Picker LJ, Streblow DN, Früh K, Malouli D | PLoS pathogens | 33232376 | PLoS Pathog | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33232376 |
Maternal Antibody Responses and Nonprimary Congenital Cytomegalovirus Infection of HIV-1-Exposed Infants. | Bialas KM, Westreich D, Cisneros de la Rosa E, Nelson CS, Kauvar LM, Fu TM, Permar SR | The Journal of infectious diseases | 27923951 | J Infect Dis | 2016 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/27923951 |
Intrahost Dynamics of Human Cytomegalovirus Variants Acquired by Seronegative Glycoprotein B Vaccinees. | Nelson CS, Vera Cruz D, Su M, Xie G, Vandergrift N, Pass RF, Forman M, Diener-West M, Koelle K, Arav-Boger R, Permar SR | Journal of virology | 30518646 | J Virol | 2019 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/30518646 |
Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus Infection. | Weimer KED, Roark H, Fisher K, Cotten CM, Kaufman DA, Bidegain M, Permar SR | American journal of perinatology | 32069486 | Am J Perinatol | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32069486 |
Maternal immune correlates of protection against placental transmission of cytomegalovirus. | Itell HL, Nelson CS, Martinez DR, Permar SR | Placenta | 28456432 | Placenta | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/28456432 |
A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection. | Nelson CS, Herold BC, Permar SR | NPJ vaccines | 30275984 | NPJ Vaccines | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30275984 |
HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions. | Nelson CS, Huffman T, Jenks JA, Cisneros de la Rosa E, Xie G, Vandergrift N, Pass RF, Pollara J, Permar SR | Proceedings of the National Academy of Sciences of the United States of America | 29712861 | Proc Natl Acad Sci U S A | 2018 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/29712861 |
Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG? | Martinez DR, Fouda GG, Peng X, Ackerman ME, Permar SR | PLoS pathogens | 30161231 | PLoS Pathog | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30161231 |
Animal Models of Congenital Cytomegalovirus Transmission: Implications for Vaccine Development. | Roark HK, Jenks JA, Permar SR, Schleiss MR | The Journal of infectious diseases | 32134481 | J Infect Dis | 2020 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/32134481 |
Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys. | Kaur A, Itell HL, Ehlinger EP, Varner V, Gantt S, Permar SR | PloS one | 30356332 | PLoS One | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30356332 |
Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants. | Martinez DR, Tu JJ, Kumar A, Mangold JF, Mangan RJ, Goswami R, Giorgi EE, Chen J, Mengual M, Douglas AO, Heimsath H, Saunders KO, Nicely NI, Eudailey J, Hernandez G, Morgan-Asiedu PK, Wiehe K, Haynes BF, Moody MA, LaBranche C, Montefiori DC, Gao F, Permar SR | mBio | 32156815 | mBio | 2020 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/32156815 |
Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection. | Moström M, Yu S, Tran D, Saccoccio F, Versoza CJ, Malouli D, Mirza A, Valencia S, Gilbert M, Blair R, Hansen S, Barry P, Früh K, Jensen JD, Pfeifer SP, Kowalik TF, Permar SR, Kaur A | bioRxiv : the preprint server for biology | 37090643 | bioRxiv | 2023 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/37090643 |
Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques. | Singh T, Miller IG, Venkatayogi S, Webster H, Heimsath HJ, Eudailey JA, Dudley DM, Kumar A, Mangan RJ, Thein A, Aliota MT, Newman CM, Mohns MS, Breitbach ME, Berry M, Friedrich TC, Wiehe K, O'Connor DH, Permar SR | mBio | 38349142 | mBio | 2024 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/38349142 |
Hyperspectral Microscopy of Near-Infrared Fluorescence Enables 17-Chirality Carbon Nanotube Imaging. | Roxbury D, Jena PV, Williams RM, Enyedi B, Niethammer P, Marcet S, Verhaegen M, Blais-Ouellette S, Heller DA | Scientific reports | 26387482 | Sci Rep | 2015 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/26387482 |
Quantitative self-assembly prediction yields targeted nanomedicines. | Shamay Y, Shah J, Işık M, Mizrachi A, Leibold J, Tschaharganeh DF, Roxbury D, Budhathoki-Uprety J, Nawaly K, Sugarman JL, Baut E, Neiman MR, Dacek M, Ganesh KS, Johnson DC, Sridharan R, Chu EL, Rajasekhar VK, Lowe SW, Chodera JD, Heller DA | Nature materials | 29403054 | Nat Mater | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29403054 |
Electroporation-induced changes in tumor vasculature and microenvironment can promote the delivery and increase the efficacy of sorafenib nanoparticles. | Kodama H, Shamay Y, Kimura Y, Shah J, Solomon SB, Heller D, Srimathveeravalli G | Bioelectrochemistry (Amsterdam, Netherlands) | 31306879 | Bioelectrochemistry | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31306879 |
Single-Chirality Near-Infrared Carbon Nanotube Sub-Cellular Imaging and FRET Probes. | Langenbacher R, Budhathoki-Uprety J, Jena PV, Roxbury D, Streit J, Zheng M, Heller DA | Nano letters | 34296885 | Nano Lett | 2021 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/34296885 |
Glutathione-S-transferase Fusion Protein Nanosensor. | Williams RM, Harvey JD, Budhathoki-Uprety J, Heller DA | Nano letters | 32955895 | Nano Lett | 2020 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/32955895 |
Non-Covalent Coatings on Carbon Nanotubes Mediate Photosensitizer Interactions. | Horoszko CP, Schnatz PJ, Budhathoki-Uprety J, Rao-Pothuraju RV, Koder RL, Heller DA | ACS applied materials & interfaces | 34672190 | ACS Appl Mater Interfaces | 2021 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/34672190 |
Targeted drug delivery strategies for precision medicines. | Manzari MT, Shamay Y, Kiguchi H, Rosen N, Scaltriti M, Heller DA | Nature reviews. Materials | 34950512 | Nat Rev Mater | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/34950512 |
Cell Membrane Proteins Modulate the Carbon Nanotube Optical Bandgap via Surface Charge Accumulation. | Roxbury D, Jena PV, Shamay Y, Horoszko CP, Heller DA | ACS nano | 26654246 | ACS Nano | 2016 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/26654246 |
An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo. | Galassi TV, Jena PV, Shah J, Ao G, Molitor E, Bram Y, Frankel A, Park J, Jessurun J, Ory DS, Haimovitz-Friedman A, Roxbury D, Mittal J, Zheng M, Schwartz RE, Heller DA | Science translational medicine | 30282694 | Sci Transl Med | 2018 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/30282694 |
Redox-active nanomaterials for nanomedicine applications. | Sims CM, Hanna SK, Heller DA, Horoszko CP, Johnson ME, Montoro Bustos AR, Reipa V, Riley KR, Nelson BC | Nanoscale | 28991962 | Nanoscale | 2017 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/28991962 |
Long-term in vivo biocompatibility of single-walled carbon nanotubes. | Galassi TV, Antman-Passig M, Yaari Z, Jessurun J, Schwartz RE, Heller DA | PloS one | 32374764 | PLoS One | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32374764 |
Hyperspectral Counting of Multiplexed Nanoparticle Emitters in Single Cells and Organelles. | Jena PV, Gravely M, Cupo C, Safaee MM, Roxbury D, Heller DA | ACS nano | 35049273 | ACS Nano | 2022 Feb 22 | https://www.ncbi.nlm.nih.gov/pubmed/35049273 |
Harnessing nanotechnology to expand the toolbox of chemical biology. | Williams RM, Chen S, Langenbacher RE, Galassi TV, Harvey JD, Jena PV, Budhathoki-Uprety J, Luo M, Heller DA | Nature chemical biology | 33414556 | Nat Chem Biol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33414556 |
A Carbon Nanotube Reporter of miRNA Hybridization Events In Vivo. | Harvey JD, Jena PV, Baker HA, Zerze GH, Williams RM, Galassi TV, Roxbury D, Mittal J, Heller DA | Nature biomedical engineering | 28845337 | Nat Biomed Eng | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28845337 |
Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinoma. | Mizrachi A, Shamay Y, Shah J, Brook S, Soong J, Rajasekhar VK, Humm JL, Healey JH, Powell SN, Baselga J, Heller DA, Haimovitz-Friedman A, Scaltriti M | Nature communications | 28194032 | Nat Commun | 2017 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/28194032 |
Nanosensor-based monitoring of autophagy-associated lysosomal acidification in vivo. | Kim M, Chen C, Yaari Z, Frederiksen R, Randall E, Wollowitz J, Cupo C, Wu X, Shah J, Worroll D, Lagenbacher RE, Goerzen D, Li YM, An H, Wang Y, Heller DA | Nature chemical biology | 37322156 | Nat Chem Biol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37322156 |
Optical Voltammetry of Polymer-Encapsulated Single-Walled Carbon Nanotubes. | Horoszko CP, Jena PV, Roxbury D, Rotkin SV, Heller DA | The journal of physical chemistry. C, Nanomaterials and interfaces | 32690989 | J Phys Chem C Nanomater Interfaces | 2019 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/32690989 |
Nanoreporter of an Enzymatic Suicide Inactivation Pathway. | Yaari Z, Cheung JM, Baker HA, Frederiksen RS, Jena PV, Horoszko CP, Jiao F, Scheuring S, Luo M, Heller DA | Nano letters | 33119310 | Nano Lett | 2020 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/33119310 |
Single Nanotube Spectral Imaging To Determine Molar Concentrations of Isolated Carbon Nanotube Species. | Galassi TV, Jena PV, Roxbury D, Heller DA | Analytical chemistry | 28194986 | Anal Chem | 2017 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/28194986 |
A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux. | Jena PV, Roxbury D, Galassi TV, Akkari L, Horoszko CP, Iaea DB, Budhathoki-Uprety J, Pipalia N, Haka AS, Harvey JD, Mittal J, Maxfield FR, Joyce JA, Heller DA | ACS nano | 28898055 | ACS Nano | 2017 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/28898055 |
P-selectin is a nanotherapeutic delivery target in the tumor microenvironment. | Shamay Y, Elkabets M, Li H, Shah J, Brook S, Wang F, Adler K, Baut E, Scaltriti M, Jena PV, Gardner EE, Poirier JT, Rudin CM, Baselga J, Haimovitz-Friedman A, Heller DA | Science translational medicine | 27358497 | Sci Transl Med | 2016 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/27358497 |
An in Vivo Nanosensor Measures Compartmental Doxorubicin Exposure. | Harvey JD, Williams RM, Tully KM, Baker HA, Shamay Y, Heller DA | Nano letters | 31244242 | Nano Lett | 2019 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/31244242 |
HIV Detection via a Carbon Nanotube RNA Sensor. | Harvey JD, Baker HA, Ortiz MV, Kentsis A, Heller DA | ACS sensors | 31056899 | ACS Sens | 2019 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/31056899 |
Helical polycarbodiimide cloaking of carbon nanotubes enables inter-nanotube exciton energy transfer modulation. | Budhathoki-Uprety J, Jena PV, Roxbury D, Heller DA | Journal of the American Chemical Society | 25343218 | J Am Chem Soc | 2014 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/25343218 |
A Fluorescent Carbon Nanotube Sensor Detects the Metastatic Prostate Cancer Biomarker uPA. | Williams RM, Lee C, Heller DA | ACS sensors | 30169018 | ACS Sens | 2018 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/30169018 |
Photoluminescent carbon nanotubes interrogate the permeability of multicellular tumor spheroids. | Jena PV, Shamay Y, Shah J, Roxbury D, Paknejad N, Heller DA | Carbon | 26456974 | Carbon N Y | 2016 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/26456974 |
DNA-Carbon Nanotube Complexation Affinity and Photoluminescence Modulation Are Independent. | Jena PV, Safaee MM, Heller DA, Roxbury D | ACS applied materials & interfaces | 28573867 | ACS Appl Mater Interfaces | 2017 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/28573867 |
A Carbon Nanotube Optical Sensor Reports Nuclear Entry via a Noncanonical Pathway. | Budhathoki-Uprety J, Langenbacher RE, Jena PV, Roxbury D, Heller DA | ACS nano | 28398031 | ACS Nano | 2017 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/28398031 |
Mesoscale nanoparticles selectively target the renal proximal tubule epithelium. | Williams RM, Shah J, Ng BD, Minton DR, Gudas LJ, Park CY, Heller DA | Nano letters | 25811353 | Nano Lett | 2015 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/25811353 |
Advances in the clinical translation of nanotechnology. | Scheinberg DA, Grimm J, Heller DA, Stater EP, Bradbury M, McDevitt MR | Current opinion in biotechnology | 28187340 | Curr Opin Biotechnol | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28187340 |
Selective Nanoparticle Targeting of the Renal Tubules. | Williams RM, Shah J, Tian HS, Chen X, Geissmann F, Jaimes EA, Heller DA | Hypertension (Dallas, Tex. : 1979) | 29133360 | Hypertension | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29133360 |
Noninvasive ovarian cancer biomarker detection via an optical nanosensor implant. | Williams RM, Lee C, Galassi TV, Harvey JD, Leicher R, Sirenko M, Dorso MA, Shah J, Olvera N, Dao F, Levine DA, Heller DA | Science advances | 29675469 | Sci Adv | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29675469 |
Nanomedicines for kidney diseases. | Williams RM, Jaimes EA, Heller DA | Kidney international | 27292222 | Kidney Int | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27292222 |
Control of Carbon Nanotube Solvatochromic Response to Chemotherapeutic Agents. | Harvey JD, Baker HA, Mercer E, Budhathoki-Uprety J, Heller DA | ACS applied materials & interfaces | 29048868 | ACS Appl Mater Interfaces | 2017 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/29048868 |
Synthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes. | Mulvey JJ, Feinberg EN, Alidori S, McDevitt MR, Heller DA, Scheinberg DA | International journal of nanomedicine | 25228803 | Int J Nanomedicine | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25228803 |
Pollen grains for oral vaccination. | Atwe SU, Ma Y, Gill HS | Journal of controlled release : official journal of the Controlled Release Society | 25151980 | J Control Release | 2014 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/25151980 |
Pollen grains as a novel microcarrier for oral delivery of proteins. | Lale SV, Gill HS | International journal of pharmaceutics | 30308271 | Int J Pharm | 2018 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/30308271 |
A chemical treatment method for obtaining clean and intact pollen shells of different species. | Gonzalez-Cruz P, Uddin MJ, Atwe SU, Abidi N, Gill HS | ACS biomaterials science & engineering | 31106262 | ACS Biomater Sci Eng | 2018 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/31106262 |
Demystifying particle-based oral vaccines. | Gonzalez-Cruz P, Gill HS | Expert opinion on drug delivery | 34148474 | Expert Opin Drug Deliv | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/34148474 |
Physical and Biochemical Characterization of Chemically Treated Pollen Shells for Potential Use in Oral Delivery of Therapeutics. | Uddin MJ, Liyanage S, Abidi N, Gill HS | Journal of pharmaceutical sciences | 30096353 | J Pharm Sci | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30096353 |
Ragweed pollen as an oral vaccine delivery system: Mechanistic insights. | Uddin MJ, Gill HS | Journal of controlled release : official journal of the Controlled Release Society | 29054371 | J Control Release | 2017 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/29054371 |
From allergen to oral vaccine carrier: A new face of ragweed pollen. | Uddin MJ, Gill HS | International journal of pharmaceutics | 29729407 | Int J Pharm | 2018 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/29729407 |
Role of Sporopollenin Shell Interfacial Properties in Protein Adsorption. | Uddin MJ, Liyanage S, Warzywoda J, Abidi N, Gill HS | Langmuir : the ACS journal of surfaces and colloids | 35212551 | Langmuir | 2022 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/35212551 |
Mucosal vaccine delivery: Current state and a pediatric perspective. | Shakya AK, Chowdhury MYE, Tao W, Gill HS | Journal of controlled release : official journal of the Controlled Release Society | 26860287 | J Control Release | 2016 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/26860287 |
Comparative profiling of cellular gait on adhesive micropatterns defines statistical patterns of activity that underlie native and cancerous cell dynamics. | Ahn JC, Coyle SM | bioRxiv : the preprint server for biology | 37961146 | bioRxiv | 2023 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/37961146 |
A programmable reaction-diffusion system for spatiotemporal cell signaling circuit design. | Rajasekaran R, Chang CC, Weix EWZ, Galateo TM, Coyle SM | Cell | 38181787 | Cell | 2024 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/38181787 |
Synthetic forms most beautiful: engineering insights into self-organization. | Xu Z, Chang CC, Coyle S | Physiology (Bethesda, Md.) | 39938118 | Physiology (Bethesda) | 2025 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/39938118 |
Genetically encoded protein oscillators for FM streaming of single-cell data. | Rajasekaran R, Galateo TM, Xu Z, Bolshakov DT, Weix EWZ, Coyle SM | bioRxiv : the preprint server for biology | 40060462 | bioRxiv | 2025 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/40060462 |
Regulatable assembly of synthetic microtubule architectures using engineered MAP-IDR condensates. | Chang CC, Coyle SM | bioRxiv : the preprint server for biology | 38105997 | bioRxiv | 2023 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/38105997 |
A mitochondrial redox switch licenses the onset of morphogenesis in animals. | Kahlon U, Ricca FD, Pillai SJ, Olivetta M, Tharp KM, Jao LE, Dudin O, McDonald K, Aydogan MG | bioRxiv : the preprint server for biology | 39553983 | bioRxiv | 2024 Oct 29 | https://www.ncbi.nlm.nih.gov/pubmed/39553983 |
Cytoplasmic division cycles without the nucleus and mitotic CDK/cyclin complexes. | Bakshi A, Iturra FE, Alamban A, Rosas-Salvans M, Dumont S, Aydogan MG | Cell | 37832525 | Cell | 2023 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/37832525 |
Dissecting host-microbe interactions with modern functional genomics. | Russell BJ, Verma M, Maier NK, Jost M | Current opinion in microbiology | 39368241 | Curr Opin Microbiol | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39368241 |
Nonpathogenic E. coli engineered to surface display cytokines as a new platform for immunotherapy. | Yang S, Sheffer M, Kaplan IE, Wang Z, Tarannum M, Dinh K, Abdulhamid Y, Shapiro R, Porter R, Soiffer R, Ritz J, Koreth J, Wei Y, Chen P, Zhang K, Márquez-Pellegrin V, Bonanno S, Joshi N, Guan M, Yang M, Li D, Bellini C, Chen J, Wu CJ, Barbie D, Li J, Romee R | Research square | 38562821 | Res Sq | 2024 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/38562821 |
A New Bacterial Chassis for Enhanced Surface Display of Recombinant Proteins. | Zhang R, Ye N, Wang Z, Yang S, Li J | Cellular and molecular bioengineering | 39513006 | Cell Mol Bioeng | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39513006 |
Engineering Tripartite Gene Editing Machinery for Highly Efficient Non-Viral Targeted Genome Integration. | Nam H, Xie K, Majumdar I, Yang S, Starzyk J, Lee D, Shan R, Li J, Wu H | Research square | 37961210 | Res Sq | 2023 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/37961210 |
Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses. | Yang S, Sheffer M, Kaplan IE, Wang Z, Tarannum M, Dinh K, Abdulhamid Y, Bobilev E, Shapiro R, Porter R, Soiffer R, Ritz J, Koreth J, Wei Y, Chen P, Zhang K, Márquez-Pellegrin V, Bonanno S, Joshi N, Guan M, Yang M, Li D, Bellini C, Liu F, Chen J, Wu CJ, Barbie D, Li J, Romee R | Nature biotechnology | 39367093 | Nat Biotechnol | 2024 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/39367093 |
Squeezable Hydrogel Microparticles for Single Extracellular Vesicle Protein Profiling. | Roh YH, Morales RT, Huynh E, Chintapula U, Reynolds DE, Agosto-Nieves RJ, Oh D, Seiner AJ, Lim J, Rodell CB, Ko J | Small (Weinheim an der Bergstrasse, Germany) | 39468876 | Small | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39468876 |
Targeted protein relocalization via protein transport coupling. | Ng CSC, Liu A, Cui B, Banik SM | Nature | 39294374 | Nature | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39294374 |
Self-Assembled Nanocoatings Protect Microbial Fertilizers for Climate-Resilient Agriculture. | Burke B, Fan G, Wasuwanich P, Moore EB, Furst AL | JACS Au | 38034965 | JACS Au | 2023 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/38034965 |
Transferrin receptor targeting chimeras for membrane protein degradation. | Zhang D, Duque-Jimenez J, Facchinetti F, Brixi G, Rhee K, Feng WW, Jänne PA, Zhou X | Nature | 39322661 | Nature | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39322661 |
A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA. | Ranzau BL, Robinson TD, Scully JM, Kapelczak ED, Dean TS, TeSlaa T, Schmitt DL | ACS bio & med chem Au | 39990938 | ACS Bio Med Chem Au | 2025 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/39990938 |
A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA. | Ranzau BL, Robinson TD, Scully JM, Kapelczack ED, Dean TS, TeSlaa T, Schmitt DL | bioRxiv : the preprint server for biology | 39386450 | bioRxiv | 2024 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/39386450 |
Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability. | Bai D, Cao Z, Attada N, Song J, Zhu C | Nature methods | 40128288 | Nat Methods | 2025 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/40128288 |
A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction. | Li X, Gamuyao R, Wu ML, Cho WJ, Kurtz NB, King SV, Petersen RA, Stabley DR, Lindow C, Climer L, Shirinifard A, Ferrara F, Throm RE, Robinson CG, Carisey A, Tebo AG, Chang CL | bioRxiv : the preprint server for biology | 38076863 | bioRxiv | 2023 Nov 29 | https://www.ncbi.nlm.nih.gov/pubmed/38076863 |
A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction. | Li X, Gamuyao R, Wu ML, Cho WJ, King SV, Petersen RA, Stabley DR, Lindow C, Climer LK, Shirinifard A, Ferrara F, Throm RE, Robinson CG, Zhou Y, Carisey AF, Tebo AG, Chang CL | The Journal of cell biology | 38949658 | J Cell Biol | 2024 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/38949658 |
Models for human telomere C-strand fill-in by CST-Polα-primase. | He Q, Lim CJ | Trends in biochemical sciences | 37586999 | Trends Biochem Sci | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37586999 |
Small LEA proteins as an effective air-water interface protectant for fragile samples during cryo-EM grid plunge freezing. | Abe KM, Lim CJ | bioRxiv : the preprint server for biology | 38370693 | bioRxiv | 2024 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/38370693 |
Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing. | Abe KM, Li G, He Q, Grant T, Lim CJ | Nature communications | 39231985 | Nat Commun | 2024 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/39231985 |
MitoTNT: Mitochondrial Temporal Network Tracking for 4D live-cell fluorescence microscopy data. | Wang Z, Natekar P, Tea C, Tamir S, Hakozaki H, Schöneberg J | PLoS computational biology | 37083820 | PLoS Comput Biol | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37083820 |
LiveLattice: Real-time visualization of tilted light-sheet microscopy data using a memory-efficient transformation algorithm. | Wang Z, Hakozaki H, McMahon G, Medina-Carbonero M, Schöneberg J | bioRxiv : the preprint server for biology | 38854017 | bioRxiv | 2024 May 30 | https://www.ncbi.nlm.nih.gov/pubmed/38854017 |
LiveLattice: Real-time visualisation of tilted light-sheet microscopy data using a memory-efficient transformation algorithm. | Wang Z, Hakozaki H, McMahon G, Medina-Carbonero M, Schöneberg J | Journal of microscopy | 39360400 | J Microsc | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39360400 |
OpenTn5: Open-Source Resource for Robust and Scalable Tn5 Transposase Purification and Characterization. | Soroczynski J, Anderson LJ, Yeung JL, Rendleman JM, Oren DA, Konishi HA, Risca VI | bioRxiv : the preprint server for biology | 39026714 | bioRxiv | 2024 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/39026714 |
Determining mesoscale chromatin structure parameters from spatially correlated cleavage data using a coarse-grained oligonucleosome model. | Clerkin AB, Pagane N, West DW, Spakowitz AJ, Risca VI | bioRxiv : the preprint server for biology | 39131347 | bioRxiv | 2024 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/39131347 |
A nucleosome switch primes Hepatitis B Virus infection. | Prescott NA, Mansisidor A, Bram Y, Biaco T, Rendleman J, Faulkner SC, Lemmon AA, Lim C, Hamard PJ, Koche RP, Risca VI, Schwartz RE, David Y | bioRxiv : the preprint server for biology | 38915612 | bioRxiv | 2024 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/38915612 |
Technological advances in probing 4D genome organization. | Soroczynski J, Risca VI | Current opinion in cell biology | 37556867 | Curr Opin Cell Biol | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37556867 |
Chromatin accessibility: methods, mechanisms, and biological insights. | Mansisidor AR, Risca VI | Nucleus (Austin, Tex.) | 36404679 | Nucleus | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36404679 |
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III. | Chen B, Stark DC, Jadhav PV, Lynn-Nguyen TM, Halligan BS, Rossiter NJ, Sindoni N, Shin M, Paulo JA, Chang M, Koo I, Koshkin S, Eyunni S, Ronchi P, Paulsen MT, Morlacchi P, Hanna DA, Lin J, Guerra RM, Pagliarini DJ, Banerjee R, Parolia A, Ljungman ME, Patterson AD, Mancias JD, Mosalaganti S, Sexton JZ, Calì T, Lyssiotis CA, Shah YM | bioRxiv : the preprint server for biology | 38352460 | bioRxiv | 2024 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/38352460 |
Rapid structural analysis of bacterial ribosomes in situ. | Powell BM, Brant TS, Davis JH, Mosalaganti S | Communications biology | 39875527 | Commun Biol | 2025 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/39875527 |
Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT). | Navratna V, Kumar A, Rana JK, Mosalaganti S | bioRxiv : the preprint server for biology | 37961489 | bioRxiv | 2024 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/37961489 |
Rapid structural analysis of bacterial ribosomes in situ. | Powell BM, Brant TS, Davis JH, Mosalaganti S | bioRxiv : the preprint server for biology | 38585831 | bioRxiv | 2024 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/38585831 |
Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain. | Navratna V, Kumar A, Rana JK, Mosalaganti S | Life science alliance | 38925866 | Life Sci Alliance | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/38925866 |
Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT). | Navratna V, Kumar A, Rana JK, Mosalaganti S | eLife | 39196614 | Elife | 2024 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/39196614 |
Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain. | Navratna V, Kumar A, Rana JK, Mosalaganti S | bioRxiv : the preprint server for biology | 38187772 | bioRxiv | 2024 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/38187772 |
Molecular Visualization of Neuronal TDP43 Pathology In Situ. | Erwin AL, Chang ML, Fernandez MG, Attili D, Russ JE, Sutanto R, Pinarbasi ES, Bekier M, Brant TS, Hahn T, Dykstra M, Thomas D, Li X, Baldridge RD, Tank EMH, Barmada SJ, Mosalaganti S | bioRxiv : the preprint server for biology | 39229019 | bioRxiv | 2024 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/39229019 |
LiFT (a Lithium Fiber-Based Test): An At-Home Companion Diagnostics for a Safer Lithium Therapy in Bipolar Disorder. | Amirghasemi F, Nejad SK, Chen R, Soleimani A, Ong V, Shroff N, Eftekhari T, Ushijima K, Ainla A, Siegel S, Mousavi MPS | Advanced healthcare materials | 38563494 | Adv Healthc Mater | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38563494 |
Flexible Acetylcholine Neural Probe with a Hydrophobic Laser-Induced Graphene Electrode and a Fluorous-Phase Sensing Membrane. | Amirghasemi F, Al-Shami A, Ushijima K, Mousavi MPS | ACS materials letters | 39309214 | ACS Mater Lett | 2024 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/39309214 |
Towards sustainable and humane dairy farming: A low-cost electrochemical sensor for on-site diagnosis of milk fever. | Soleimani A, Amirghasemi F, Al-Shami A, Khazaee Nejad S, Tsung A, Wang Y, Lara Galindo S, Parvin D, Olson A, Avishai A, Mousavi MPS | Biosensors & bioelectronics | 38749287 | Biosens Bioelectron | 2024 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/38749287 |
SPOOC (Sensor for Periodic Observation of Choline): An Integrated Lab-on-a-Spoon Platform for At-Home Quantification of Choline in Infant Formula. | Al-Shami A, Amirghasemi F, Soleimani A, Khazaee Nejad S, Ong V, Berkmen A, Ainla A, Mousavi MPS | Small (Weinheim an der Bergstrasse, Germany) | 38587168 | Small | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38587168 |
Toward Personalized Treatment of Depression: An Affordable Citalopram Test based on a Solid-Contact Potentiometric Electrode for at-Home Monitoring of the Antidepressant Dosage. | Chen R, Amirghasemi F, Ma H, Ong V, Tran A, Mousavi MPS | ACS sensors | 37734027 | ACS Sens | 2023 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/37734027 |
Lab-on-a-lollipop (LoL) platform for preventing food-induced toxicity: all-in-one system for saliva sampling and electrochemical detection of vanillin. | Ma H, Khazaee Nejad S, Vargas Ramos D, Al-Shami A, Soleimani A, Amirghasemi F, Mohamed MA, Mousavi MPS | Lab on a chip | 39207360 | Lab Chip | 2024 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/39207360 |
Expansion microscopy: A chemical approach for super-resolution microscopy. | Zhuang Y, Shi X | Current opinion in structural biology | 37253290 | Curr Opin Struct Biol | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37253290 |
RBBP6 anchors pre-mRNA 3' end processing to nuclear speckles for efficient gene expression. | Yoon Y, Bournique E, Soles LV, Yin H, Chu HF, Yin C, Zhuang Y, Liu X, Liu L, Jeong J, Yu C, Valdez M, Tian L, Huang L, Shi X, Seelig G, Ding F, Tong L, Buisson R, Shi Y | Molecular cell | 39798570 | Mol Cell | 2025 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/39798570 |
Cationic peptides erase memories by removing synaptic AMPA receptors through endophilin-mediated endocytosis. | Stokes E, Zhuang Y, Toledano M, Vasquez J, Azouz G, Hui M, Tyler I, Shi X, Aoto J, Beier KT | Research square | 38045269 | Res Sq | 2023 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/38045269 |
Label-Retention Expansion Microscopy (LR-ExM) for Enhanced Fluorescent Signals using Trifunctional Probes. | Zhuang Y, Shi X | Current protocols | 38265180 | Curr Protoc | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/38265180 |
Proximity labeling expansion microscopy (PL-ExM) evaluates interactome labeling techniques. | Park S, Wang X, Mo Y, Zhang S, Li X, Fong KC, Yu C, Tran AA, Scipioni L, Dai Z, Huang X, Huang L, Shi X | Journal of materials chemistry. B | 39105364 | J Mater Chem B | 2024 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/39105364 |
Proximity Labeling Expansion Microscopy (PL-ExM) resolves structure of the interactome. | Park S, Wang X, Li X, Huang X, Fong KC, Yu C, Tran AA, Scipioni L, Dai Z, Huang L, Shi X | bioRxiv : the preprint server for biology | 38014020 | bioRxiv | 2023 Nov 13 | https://www.ncbi.nlm.nih.gov/pubmed/38014020 |
Coaching ribosome biogenesis from the nuclear periphery. | Zhuang Y, Guo X, Razorenova OV, Miles CE, Zhao W, Shi X | bioRxiv : the preprint server for biology | 38948754 | bioRxiv | 2024 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/38948754 |
Enhanced dynamic coupling in a nuclear receptor underlies ligand activity. | Yu T, Villalona P, Khan SH, Mikeasky N, Meinert E, Magafas J, Pulahinge T, Bader A, Okafor CD | The Journal of biological chemistry | 39675705 | J Biol Chem | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39675705 |
Phase Separation in Biology and Disease; Current Perspectives and Open Questions. | Boeynaems S, Chong S, Gsponer J, Holt L, Milovanovic D, Mitrea DM, Mueller-Cajar O, Portz B, Reilly JF, Reinkemeier CD, Sabari BR, Sanulli S, Shorter J, Sontag E, Strader L, Stachowiak J, Weber SC, White M, Zhang H, Zweckstetter M, Elbaum-Garfinkle S, Kriwacki R | Journal of molecular biology | 36690068 | J Mol Biol | 2023 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/36690068 |
Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection. | Abdullah L, Emiliani FE, Vaidya CM, Stuart H, Kolling FW, Ackerman ME, Song L, McKenna A, Huang YH | bioRxiv : the preprint server for biology | 38585810 | bioRxiv | 2024 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/38585810 |
The endogenous antigen-specific CD8(+) T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments. | Abdullah L, Emiliani FE, Vaidya CM, Stuart H, Musial SC, Kolling FW, Obar JJ, Rosato PC, Ackerman ME, Song L, McKenna A, Huang YH | Immunity | 40020673 | Immunity | 2025 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/40020673 |
Programmability and biomedical utility of intrinsically-disordered protein polymers. | Giraldo-Castaño MC, Littlejohn KA, Avecilla ARC, Barrera-Villamizar N, Quiroz FG | Advanced drug delivery reviews | 39094909 | Adv Drug Deliv Rev | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39094909 |
Genetically-encoded phase separation sensors for intracellular probing of biomolecular condensates. | Regina Chua Avecilla A, Thomas J, Quiroz FG | bioRxiv : the preprint server for biology | 39257779 | bioRxiv | 2024 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/39257779 |
Genetically-Encoded Phase Separation Sensors Enable High-Fidelity Live-Cell Probing of Biomolecular Condensates. | Avecilla ARC, Thomas J, Quiroz FG | ACS sensors | 39987501 | ACS Sens | 2025 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/39987501 |
Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning. | Laubscher E, Wang XJ, Razin N, Dougherty T, Xu RJ, Ombelets L, Pao E, Graf W, Moffitt JR, Yue Y, Van Valen D | bioRxiv : the preprint server for biology | 37732188 | bioRxiv | 2024 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/37732188 |
Generalized cell phenotyping for spatial proteomics with language-informed vision models. | Wang XJ, Dilip R, Bussi Y, Brown C, Pradhan E, Jain Y, Yu K, Li S, Abt M, Börner K, Keren L, Yue Y, Barnowski R, Van Valen D | bioRxiv : the preprint server for biology | 39605651 | bioRxiv | 2024 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/39605651 |
CellSAM: A Foundation Model for Cell Segmentation. | Israel U, Marks M, Dilip R, Li Q, Yu C, Laubscher E, Iqbal A, Pradhan E, Ates A, Abt M, Brown C, Pao E, Li S, Pearson-Goulart A, Perona P, Gkioxari G, Barnowski R, Yue Y, Van Valen D | bioRxiv : the preprint server for biology | 38045277 | bioRxiv | 2025 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/38045277 |
A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation. | Yanchus C, Drucker KL, Kollmeyer TM, Tsai R, Winick-Ng W, Liang M, Malik A, Pawling J, De Lorenzo SB, Ali A, Decker PA, Kosel ML, Panda A, Al-Zahrani KN, Jiang L, Browning JWL, Lowden C, Geuenich M, Hernandez JJ, Gosio JT, Ahmed M, Loganathan SK, Berman J, Trcka D, Michealraj KA, Fortin J, Carson B, Hollingsworth EW, Jacinto S, Mazrooei P, Zhou L, Elia A, Lupien M, He HH, Murphy DJ, Wang L, Abyzov A, Dennis JW, Maass PG, Campbell K, Wilson MD, Lachance DH, Wrensch M, Wiencke J, Mak T, Pennacchio LA, Dickel DE, Visel A, Wrana J, Taylor MD, Zadeh G, Dirks P, Eckel-Passow JE, Attisano L, Pombo A, Ida CM, Kvon EZ, Jenkins RB, Schramek D | Science (New York, N.Y.) | 36201590 | Science | 2022 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/36201590 |
Conserved Cis-Acting Range Extender Element Mediates Extreme Long-Range Enhancer Activity in Mammals. | Bower G, Hollingsworth EW, Jacinto S, Clock B, Cao K, Liu M, Dziulko A, Alcaina-Caro A, Xu Q, Skowronska-Krawczyk D, Lopez-Rios J, Dickel DE, Bardet AF, Pennacchio LA, Visel A, Kvon EZ | bioRxiv : the preprint server for biology | 38826394 | bioRxiv | 2024 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/38826394 |
Genetic factors mediating long-range enhancer-promoter communication in mammalian development. | Bower G, Kvon EZ | Current opinion in genetics & development | 39579740 | Curr Opin Genet Dev | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39579740 |
Increased enhancer-promoter interactions during developmental enhancer activation in mammals. | Chen Z, Snetkova V, Bower G, Jacinto S, Clock B, Dizehchi A, Barozzi I, Mannion BJ, Alcaina-Caro A, Lopez-Rios J, Dickel DE, Visel A, Pennacchio LA, Kvon EZ | Nature genetics | 38509385 | Nat Genet | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38509385 |
Rapid and Quantitative Functional Interrogation of Human Enhancer Variant Activity in Live Mice. | Hollingsworth EW, Liu TA, Jacinto SH, Chen CX, Alcantara JA, Kvon EZ | bioRxiv : the preprint server for biology | 38105996 | bioRxiv | 2023 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/38105996 |
Protocol for building a user-friendly temperature control system to support microscopes, microfluidic chambers, and custom incubators. | Liu Z, Nguyen TTT, Ding F | STAR protocols | 38294908 | STAR Protoc | 2024 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/38294908 |
Cost-efficient boundary-free surface patterning achieves high effective-throughput of time-lapse microscopy experiments. | Liang G, Yin H, Allard J, Ding F | PloS one | 36301804 | PLoS One | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36301804 |
Inferring stochastic rates from heterogeneous snapshots of particle positions. | Miles CE, McKinley SA, Ding F, Lehoucq RB | ArXiv | 37986720 | ArXiv | 2023 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/37986720 |
XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells. | Dror I, Chitiashvili T, Tan SYX, Cano CT, Sahakyan A, Markaki Y, Chronis C, Collier AJ, Deng W, Liang G, Sun Y, Afasizheva A, Miller J, Xiao W, Black DL, Ding F, Plath K | Cell | 38181737 | Cell | 2024 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/38181737 |
FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1. | Cho S, Chun Y, He L, Ramirez CB, Ganesh KS, Jeong K, Song J, Cheong JG, Li Z, Choi J, Kim J, Koundouros N, Ding F, Dephoure N, Jang C, Blenis J, Lee G | Molecular cell | 37595559 | Mol Cell | 2023 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/37595559 |
Inferring Stochastic Rates from Heterogeneous Snapshots of Particle Positions. | Miles CE, McKinley SA, Ding F, Lehoucq RB | Bulletin of mathematical biology | 38740619 | Bull Math Biol | 2024 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/38740619 |
Displacement and dissociation of oligonucleotides during DNA hairpin closure under strain. | Ding F, Cocco S, Raj S, Manosas M, Nguyen TTT, Spiering MM, Bensimon D, Allemand JF, Croquette V | Nucleic acids research | 36478056 | Nucleic Acids Res | 2022 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/36478056 |
Wafer-Scale Fabrication of Uniform, Micrometer-Sized, Triangular Membranes on Sapphire for High-Speed Protein Sensing in a Nanopore. | Xia P, Rahman Laskar MA, Wang C | ACS applied materials & interfaces | 36598264 | ACS Appl Mater Interfaces | 2023 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/36598264 |
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket. | Shi H, Ditter IA, Oken AC, Mansoor SE | Science advances | 39823330 | Sci Adv | 2025 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/39823330 |
High-affinity agonism at the P2X(7) receptor is mediated by three residues outside the orthosteric pocket. | Oken AC, Lisi NE, Krishnamurthy I, McCarthy AE, Godsey MH, Glasfeld A, Mansoor SE | Nature communications | 39107314 | Nat Commun | 2024 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/39107314 |
P2X(7) receptors exhibit at least three modes of allosteric antagonism. | Oken AC, Ditter IA, Lisi NE, Krishnamurthy I, Godsey MH, Mansoor SE | Science advances | 39365862 | Sci Adv | 2024 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/39365862 |
Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding. | Oken AC, Lisi NE, Ditter IA, Shi H, Nechiporuk NA, Mansoor SE | Nature communications | 39353889 | Nat Commun | 2024 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/39353889 |
Unlocking the secrets of ABEs: the molecular mechanism behind their specificity. | Chen X, McAndrew MJ, Lapinaite A | Biochemical Society transactions | 37526140 | Biochem Soc Trans | 2023 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/37526140 |
Dimerization of the deaminase domain and locking interactions with Cas9 boost base editing efficiency in ABE8e. | Arantes PR, Chen X, Sinha S, Saha A, Patel AC, Sample M, Nierzwicki Ł, Lapinaite A, Palermo G | Nucleic acids research | 39569582 | Nucleic Acids Res | 2024 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/39569582 |
Methods special issue: RNA-targeting technologies. | Knott GJ, Lapinaite A, O'Connell MR | Methods (San Diego, Calif.) | 36792042 | Methods | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36792042 |
The genetic engineering Swiss army knife. | King MB, Perry KN, McAndrew MJ, Lapinaite A | Nature chemistry | 38844636 | Nat Chem | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38844636 |
RNA-based programmable DNA cleavage. | King MB, Lapinaite A | Nature chemical biology | 38730193 | Nat Chem Biol | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38730193 |
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes. | Adler BA, Trinidad MI, Bellieny-Rabelo D, Zhang E, Karp HM, Skopintsev P, Thornton BW, Weissman RF, Yoon PH, Chen L, Hessler T, Eggers AR, Colognori D, Boger R, Doherty EE, Tsuchida CA, Tran RV, Hofman L, Shi H, Wasko KM, Zhou Z, Xia C, Al-Shimary MJ, Patel JR, Thomas VCJX, Pattali R, Kan MJ, Vardapetyan A, Yang A, Lahiri A, Maxwell MF, Murdock AG, Ramit GC, Henderson HR, Calvert RW, Bamert RS, Knott GJ, Lapinaite A, Pausch P, Cofsky JC, Sontheimer EJ, Wiedenheft B, Fineran PC, Brouns SJJ, Sashital DG, Thomas BC, Brown CT, Goltsman DSA, Barrangou R, Siksnys V, Banfield JF, Savage DF, Doudna JA | Nucleic acids research | 37889041 | Nucleic Acids Res | 2024 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/37889041 |
Membrane-induced 2D phase separation of the focal adhesion protein talin. | Litschel T, Kelley CF, Cheng X, Babl L, Mizuno N, Case LB, Schwille P | Nature communications | 38862544 | Nat Commun | 2024 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/38862544 |
Phase separation in chemical and mechanical signal transduction. | Cheng X, Case LB | Current opinion in cell biology | 37788587 | Curr Opin Cell Biol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37788587 |
Engineered reactivity of a bacterial E1-like enzyme enables ATP-driven modification of protein C termini. | Frazier CL, Deb D, Weeks AM | bioRxiv : the preprint server for biology | 38798401 | bioRxiv | 2024 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/38798401 |
Proteome-Derived Peptide Libraries for Deep Specificity Profiling of N-terminal Modification Reagents. | Bridge HN, Weeks AM | Current protocols | 37283519 | Curr Protoc | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37283519 |
Mycobacterium tuberculosis Evasion of Guanylate Binding Protein-Mediated Host Defense in Mice Requires the ESX1 Secretion System. | Olive AJ, Smith CM, Baer CE, Coers J, Sassetti CM | International journal of molecular sciences | 36769182 | Int J Mol Sci | 2023 Feb 2 | https://www.ncbi.nlm.nih.gov/pubmed/36769182 |
Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice. | Meade RK, Long JE, Jinich A, Rhee KY, Ashbrook DG, Williams RW, Sassetti CM, Smith CM | bioRxiv : the preprint server for biology | 36945430 | bioRxiv | 2023 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/36945430 |
Genome-wide screen identifies host loci that modulate Mycobacterium tuberculosis fitness in immunodivergent mice. | Meade RK, Long JE, Jinich A, Rhee KY, Ashbrook DG, Williams RW, Sassetti CM, Smith CM | G3 (Bethesda, Md.) | 37405387 | G3 (Bethesda) | 2023 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/37405387 |
Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice. | Wilburn KM, Meade RK, Heckenberg EM, Dockterman J, Coers J, Sassetti CM, Olive AJ, Smith CM | Infection and immunity | 36629440 | Infect Immun | 2023 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/36629440 |
An ancestral mycobacterial effector promotes dissemination of infection. | Saelens JW, Sweeney MI, Viswanathan G, Xet-Mull AM, Jurcic Smith KL, Sisk DM, Hu DD, Cronin RM, Hughes EJ, Brewer WJ, Coers J, Champion MM, Champion PA, Lowe CB, Smith CM, Lee S, Stout JE, Tobin DM | Cell | 36356582 | Cell | 2022 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/36356582 |
Resistance-resistant antibacterial treatment strategies. | Batchelder JI, Hare PJ, Mok WWK | Frontiers in antibiotics | 36845830 | Front Antibiot | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36845830 |
Agar and agarose used for Staphylococcus aureus biofilm cultivation impact fluoroquinolone tolerance. | Power AD, Mok WWK | Journal of applied microbiology | 39066496 | J Appl Microbiol | 2024 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/39066496 |
Metabolic and transcriptional activities underlie stationary-phase Pseudomonas aeruginosa sensitivity to Levofloxacin. | Hare PJ, Gonzalez JR, Quelle RM, Wu YI, Mok WWK | Microbiology spectrum | 38078717 | Microbiol Spectr | 2024 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/38078717 |
Single-Cell Technologies to Study Phenotypic Heterogeneity and Bacterial Persisters. | Hare PJ, LaGree TJ, Byrd BA, DeMarco AM, Mok WWK | Microorganisms | 34835403 | Microorganisms | 2021 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/34835403 |
Probiotic Escherichia coli Nissle 1917 inhibits bacterial persisters that survive fluoroquinolone treatment. | Hare PJ, Englander HE, Mok WWK | Journal of applied microbiology | 35332984 | J Appl Microbiol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35332984 |
Stimulating Transcription in Antibiotic-Tolerant Escherichia coli Sensitizes It to Fluoroquinolone and Nonfluoroquinolone Topoisomerase Inhibitors. | LaGree TJ, Byrd BA, Quelle RM, Schofield SL, Mok WWK | Antimicrobial agents and chemotherapy | 36951560 | Antimicrob Agents Chemother | 2023 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/36951560 |
Metabolites augment oxidative stress to sensitize antibiotic-tolerant Staphylococcus aureus to fluoroquinolones. | Batchelder JI, Taylor AJ, Mok WWK | mBio | 39475229 | mBio | 2024 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/39475229 |
First we eat, then we do everything else: The dynamic metabolic regulation of efferocytosis. | Trzeciak A, Wang YT, Perry JSA | Cell metabolism | 34433074 | Cell Metab | 2021 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/34433074 |
Phagocytosis in the retina promotes local insulin production in the eye. | Iker Etchegaray J, Kelley S, Penberthy K, Karvelyte L, Nagasaka Y, Gasperino S, Paul S, Seshadri V, Raymond M, Marco AR, Pinney J, Stremska M, Barron B, Lucas C, Wase N, Fan Y, Unanue E, Kundu B, Burstyn-Cohen T, Perry J, Ambati J, Ravichandran KS | Nature metabolism | 36732622 | Nat Metab | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36732622 |
Broad-spectrum antibiotics disrupt homeostatic efferocytosis. | Saavedra PHV, Trzeciak AJ, Lipshutz A, Daman AW, O'Neal AJ, Liu ZL, Wang Z, Romero-Pichardo JE, Rojas WS, Zago G, van den Brink MRM, Josefowicz SZ, Lucas CD, Anderson CJ, Rudensky AY, Perry JSA | Nature metabolism | 39122784 | Nat Metab | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39122784 |
Metabolic engineering to facilitate anti-tumor immunity. | Schild T, Wallisch P, Zhao Y, Wang YT, Haughton L, Chirayil R, Pierpont K, Chen K, Nunes-Violante S, Cross J, de Stanchina E, Thompson CB, Scheinberg DA, Perry JSA, Keshari KR | Cancer cell | 40020672 | Cancer Cell | 2025 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/40020672 |
Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments. | Wang YT, Trzeciak AJ, Rojas WS, Saavedra P, Chen YT, Chirayil R, Etchegaray JI, Lucas CD, Puleston DJ, Keshari KR, Perry JSA | Cell metabolism | 36584675 | Cell Metab | 2023 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/36584675 |
Dirichlet Diffusion Score Model for Biological Sequence Generation. | Avdeyev P, Shi C, Tan Y, Dudnyk K, Zhou J | ArXiv | 37292476 | ArXiv | 2023 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/37292476 |
Sequence basis of transcription initiation in the human genome. | Dudnyk K, Cai D, Shi C, Xu J, Zhou J | Science (New York, N.Y.) | 38662817 | Science | 2024 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/38662817 |
A sequence-based global map of regulatory activity for deciphering human genetics. | Chen KM, Wong AK, Troyanskaya OG, Zhou J | Nature genetics | 35817977 | Nat Genet | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35817977 |
Sequence basis of transcription initiation in human genome. | Dudnyk K, Shi C, Zhou J | bioRxiv : the preprint server for biology | 37425823 | bioRxiv | 2023 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/37425823 |
Computational Approaches for Understanding Sequence Variation Effects on the 3D Genome Architecture. | Avdeyev P, Zhou J | Annual review of biomedical data science | 35537461 | Annu Rev Biomed Data Sci | 2022 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/35537461 |
Structural variation cooperates with permissive chromatin to control enhancer hijacking-mediated oncogenic transcription. | Botten GA, Zhang Y, Dudnyk K, Kim YJ, Liu X, Sanders JT, Imanci A, Droin N, Cao H, Kaphle P, Dickerson KE, Kumar KR, Chen M, Chen W, Solary E, Ly P, Zhou J, Xu J | Blood | 36947815 | Blood | 2023 Jul 27 | https://www.ncbi.nlm.nih.gov/pubmed/36947815 |
Sequence-based modeling of three-dimensional genome architecture from kilobase to chromosome scale. | Zhou J | Nature genetics | 35551308 | Nat Genet | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35551308 |
Mitochondrially-associated actin waves maintain organelle homeostasis and equitable inheritance. | Coscia SM, Moore AS, Wong YC, Holzbaur ELF | Current opinion in cell biology | 38692079 | Curr Opin Cell Biol | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38692079 |
Super-resolution microscopy: Insights into mitochondria-lysosome crosstalk in health and disease. | Leisten ED, Woods AC, Wong YC | The Journal of cell biology | 37917024 | J Cell Biol | 2023 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/37917024 |
Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response. | Chen Y, Quan S, Patil V, Kunjamma RB, Tokars HM, Leisten ED, Joy G, Wills S, Chan JR, Wong YC, Popko B | Glia | 37203250 | Glia | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37203250 |
Improved mammalian retromer cryo-EM structures reveal a new assembly interface. | Kendall AK, Chandra M, Xie B, Wan W, Jackson LP | The Journal of biological chemistry | 36174678 | J Biol Chem | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/36174678 |
STOPGAP: an open-source package for template matching, subtomogram alignment and classification. | Wan W, Khavnekar S, Wagner J | Acta crystallographica. Section D, Structural biology | 38606666 | Acta Crystallogr D Struct Biol | 2024 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/38606666 |
TOMOMAN: a software package for large scale cryo-electron tomography data preprocessing, community data sharing, and collaborative computing. | Khavnekar S, Erdmann PS, Wan W | bioRxiv : the preprint server for biology | 38746401 | bioRxiv | 2024 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/38746401 |
An approach for coherent periodogram averaging of tilt-series data for improved CTF estimation. | Khavnekar S, Wan W | bioRxiv : the preprint server for biology | 39416009 | bioRxiv | 2024 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/39416009 |
TOMOMAN: a software package for large-scale cryo-electron tomography data preprocessing, community data sharing and collaborative computing. | Khavnekar S, Erdmann PS, Wan W | Journal of applied crystallography | 39628881 | J Appl Crystallogr | 2024 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/39628881 |
STOPGAP, an open-source package for template matching, subtomogram alignment, and classification. | Wan W, Khavnekar S, Wagner J | bioRxiv : the preprint server for biology | 38187721 | bioRxiv | 2023 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/38187721 |
Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy. | Wang W, Wu S, Cen Z, Zhang Y, Chen Y, Huang Y, Cillo AR, Prokopec JS, Quarato G, Vignali DAA, Stewart-Ornstein J, Li S, Lu B, Gong YN | Cell reports | 36323258 | Cell Rep | 2022 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/36323258 |
MLKL ubiquitylation: more than a makeover. | Wang W, Gong YN | Cell death and differentiation | 35022572 | Cell Death Differ | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35022572 |
Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression. | Sugitani N, Vendetti FP, Cipriano AJ, Pandya P, Deppas JJ, Moiseeva TN, Schamus-Haynes S, Wang Y, Palmer D, Osmanbeyoglu HU, Bostwick A, Snyder NW, Gong YN, Aird KM, Delgoffe GM, Beumer JH, Bakkenist CJ | Cell reports | 36130512 | Cell Rep | 2022 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/36130512 |
Plasma membrane repair empowers the necrotic survivors as innate immune modulators. | Xu S, Yang TJ, Xu S, Gong YN | Seminars in cell & developmental biology | 37648621 | Semin Cell Dev Biol | 2024 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/37648621 |
LANCE: a Label-Free Live Apoptotic and Necrotic Cell Explorer Using Convolutional Neural Network Image Analysis. | Hartnett EB, Zhou M, Gong YN, Chen YC | Analytical chemistry | 36251981 | Anal Chem | 2022 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/36251981 |
Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis. | Wang W, Prokopec JS, Zhang Y, Sukhoplyasova M, Shinglot H, Wang MT, Linkermann A, Stewart-Ornstein J, Gong YN | Developmental cell | 35016014 | Dev Cell | 2022 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/35016014 |
D-MAINS: A Deep-Learning Model for the Label-Free Detection of Mitosis, Apoptosis, Interphase, Necrosis, and Senescence in Cancer Cells. | He S, Sillah M, Cole AR, Uboveja A, Aird KM, Chen YC, Gong YN | Cells | 38920634 | Cells | 2024 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/38920634 |
Structural basis for dysregulation of aminolevulinic acid synthase in human disease. | Taylor JL, Brown BL | The Journal of biological chemistry | 35093382 | J Biol Chem | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35093382 |
The yeast ALA synthase C-terminus positively controls enzyme structure and function. | Tran JU, Brown BL | Protein science : a publication of the Protein Society | 36807942 | Protein Sci | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36807942 |
Elucidating the Role of Human ALAS2 C-terminal Mutations Resulting in Loss of Function and Disease. | Taylor JL, Ayres-Galhardo PH, Brown BL | Biochemistry | 38888931 | Biochemistry | 2024 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/38888931 |
Structural Basis for Allostery in PLP-dependent Enzymes. | Tran JU, Brown BL | Frontiers in molecular biosciences | 35547395 | Front Mol Biosci | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35547395 |
Assembly of RNA polymerase II transcription initiation complexes. | Farnung L, Vos SM | Current opinion in structural biology | 35183822 | Curr Opin Struct Biol | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35183822 |
Structural advances in transcription elongation. | Mohamed AA, Vazquez Nunez R, Vos SM | Current opinion in structural biology | 35816930 | Curr Opin Struct Biol | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35816930 |
Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. | Su BG, Vos SM | Molecular cell | 38401543 | Mol Cell | 2024 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/38401543 |
The structural basis for RNA slicing by human Argonaute2. | Mohamed AA, Wang PY, Bartel DP, Vos SM | Cell reports | 39932188 | Cell Rep | 2025 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/39932188 |
The structural basis for RNA slicing by human Argonaute2. | Mohamed AA, Wang PY, Bartel DP, Vos SM | bioRxiv : the preprint server for biology | 39229170 | bioRxiv | 2024 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/39229170 |
Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex. | Markert JW, Vos SM, Farnung L | Nature communications | 38065958 | Nat Commun | 2023 Dec 8 | https://www.ncbi.nlm.nih.gov/pubmed/38065958 |
Identification and characterization of a human MORC2 DNA binding region that is required for gene silencing. | Fendler NL, Ly J, Welp L, Lu D, Schulte F, Urlaub H, Vos SM | Nucleic acids research | 39739841 | Nucleic Acids Res | 2025 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/39739841 |
Structural basis of nucleosome retention during transcription elongation. | Filipovski M, Soffers JHM, Vos SM, Farnung L | Science (New York, N.Y.) | 35709268 | Science | 2022 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/35709268 |
Identification and characterization of a human MORC2 DNA binding region that is required for gene silencing. | Fendler NL, Ly J, Welp L, Urlaub H, Vos SM | bioRxiv : the preprint server for biology | 38895295 | bioRxiv | 2024 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/38895295 |
Vibrio cholerae biofilms use modular adhesins with glycan-targeting and nonspecific surface binding domains for colonization. | Huang X, Nero T, Weerasekera R, Matej KH, Hinbest A, Jiang Z, Lee RF, Wu L, Chak C, Nijjer J, Gibaldi I, Yang H, Gamble N, Ng WL, Malaker SA, Sumigray K, Olson R, Yan J | Nature communications | 37055389 | Nat Commun | 2023 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/37055389 |
Mechanical forces drive a reorientation cascade leading to biofilm self-patterning. | Nijjer J, Li C, Zhang Q, Lu H, Zhang S, Yan J | Nature communications | 34789754 | Nat Commun | 2021 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/34789754 |
Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement. | Barrasso K, Chac D, Debela MD, Geigel C, Steenhaut A, Rivera Seda A, Dunmire CN, Harris JB, Larocque RC, Midani FS, Qadri F, Yan J, Weil AA, Ng WL | eLife | 35343438 | Elife | 2022 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/35343438 |
Agent-based modeling of stress anisotropy driven nematic ordering in growing biofilms. | Li C, Nijjer J, Feng L, Zhang Q, Yan J, Zhang S | Soft matter | 38563244 | Soft Matter | 2024 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/38563244 |
Biofilms as self-shaping growing nematics. | Nijjer J, Li C, Kothari M, Henzel T, Zhang Q, Tai JB, Zhou S, Cohen T, Zhang S, Yan J | Nature physics | 39055904 | Nat Phys | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39055904 |
Interfacial cavitation. | Henzel T, Nijjer J, Chockalingam S, Wahdat H, Crosby AJ, Yan J, Cohen T | PNAS nexus | 36714841 | PNAS Nexus | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36714841 |
Vibrio cholerae RbmB is an α-1,4-polysaccharide lyase with biofilm-disrupting activity against Vibrio polysaccharide (VPS). | Weerasekera R, Moreau A, Huang X, Nam KM, Hinbest AJ, Huynh Y, Liu X, Ashwood C, Pepi LE, Paulson E, Cegelski L, Yan J, Olson R | PLoS pathogens | 39621768 | PLoS Pathog | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39621768 |
Morphogenesis of confined biofilms: how mechanical interactions determine cellular patterning and global geometry. | Nam KM, Yan J | Soft matter | 39901805 | Soft Matter | 2025 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/39901805 |
Social evolution of shared biofilm matrix components. | Tai JB, Mukherjee S, Nero T, Olson R, Tithof J, Nadell CD, Yan J | Proceedings of the National Academy of Sciences of the United States of America | 35771939 | Proc Natl Acad Sci U S A | 2022 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/35771939 |
New Insights into Vibrio cholerae Biofilms from Molecular Biophysics to Microbial Ecology. | Tai JB, Ferrell MJ, Yan J, Waters CM | Advances in experimental medicine and biology | 36792869 | Adv Exp Med Biol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36792869 |
Lipoarabinomannan mediates localized cell wall integrity during division in mycobacteria. | Sparks IL, Kado T, Prithviraj M, Nijjer J, Yan J, Morita YS | Nature communications | 38467648 | Nat Commun | 2024 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/38467648 |
Non-disruptive matrix turnover is a conserved feature of biofilm aggregate growth in paradigm pathogenic species. | Reichhardt C, Matwichuk ML, Lewerke LT, Jacobs HM, Yan J, Parsek MR | mBio | 39982068 | mBio | 2025 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/39982068 |
An Atlas of Variant Effects to understand the genome at nucleotide resolution. | Fowler DM, Adams DJ, Gloyn AL, Hahn WC, Marks DS, Muffley LA, Neal JT, Roth FP, Rubin AF, Starita LM, Hurles ME | Genome biology | 37394429 | Genome Biol | 2023 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/37394429 |
A genome-wide atlas of human cell morphology. | Ramezani M, Bauman J, Singh A, Weisbart E, Yong J, Lozada M, Way GP, Kavari SL, Diaz C, Haghighi M, Batista TM, Pérez-Schindler J, Claussnitzer M, Singh S, Cimini BA, Blainey PC, Carpenter AE, Jan CH, Neal JT | bioRxiv : the preprint server for biology | 37609130 | bioRxiv | 2023 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/37609130 |
A genome-wide atlas of human cell morphology. | Ramezani M, Weisbart E, Bauman J, Singh A, Yong J, Lozada M, Way GP, Kavari SL, Diaz C, Leardini E, Jetley G, Pagnotta J, Haghighi M, Batista TM, Pérez-Schindler J, Claussnitzer M, Singh S, Cimini BA, Blainey PC, Carpenter AE, Jan CH, Neal JT | Nature methods | 39870862 | Nat Methods | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39870862 |
BEERS2: RNA-Seq simulation through high fidelity in silico modeling. | Brooks TG, Lahens NF, Mrčela A, Sarantopoulou D, Nayak S, Naik A, Sengupta S, Choi PS, Grant GR | Briefings in bioinformatics | 38605641 | Brief Bioinform | 2024 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/38605641 |
Machine learning-optimized targeted detection of alternative splicing. | Yang K, Islas N, Jewell S, Jha A, Radens CM, Pleiss JA, Lynch KW, Barash Y, Choi PS | bioRxiv : the preprint server for biology | 39386495 | bioRxiv | 2024 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/39386495 |
Sources of non-uniform coverage in short-read RNA-Seq data. | Brooks TG, Lahens NF, Mrčela A, Yang J, Purohit S, Naik A, Ricciotti E, Sengupta S, Choi PS, Grant GR | bioRxiv : the preprint server for biology | 39975309 | bioRxiv | 2025 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/39975309 |
Machine learning-optimized targeted detection of alternative splicing. | Yang K, Islas N, Jewell S, Wu D, Jha A, Radens CM, Pleiss JA, Lynch KW, Barash Y, Choi PS | Nucleic acids research | 39727154 | Nucleic Acids Res | 2025 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/39727154 |
BEERS2: RNA-Seq simulation through high fidelity in silico modeling. | Brooks TG, Lahens NF, Mrčela A, Sarantopoulou D, Nayak S, Naik A, Sengupta S, Choi PS, Grant GR | bioRxiv : the preprint server for biology | 37162982 | bioRxiv | 2023 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/37162982 |
cGLRs are a diverse family of pattern recognition receptors in animal innate immunity. | Li Y, Slavik KM, Morehouse BR, de Oliveira Mann CC, Mears K, Liu J, Kashin D, Schwede F, Kranzusch PJ | bioRxiv : the preprint server for biology | 36865129 | bioRxiv | 2023 Feb 22 | https://www.ncbi.nlm.nih.gov/pubmed/36865129 |
Structural basis of human TREX1 DNA degradation and autoimmune disease. | Zhou W, Richmond-Buccola D, Wang Q, Kranzusch PJ | Nature communications | 35879334 | Nat Commun | 2022 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/35879334 |
Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity. | Hobbs SJ, Wein T, Lu A, Morehouse BR, Schnabel J, Leavitt A, Yirmiya E, Sorek R, Kranzusch PJ | Nature | 35395152 | Nature | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35395152 |
Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS. | Scott TM, Arnold LM, Powers JA, McCann DA, Rowe AB, Christensen DE, Pereira MJ, Zhou W, Torrez RM, Iwasa JH, Kranzusch PJ, Sundquist WI, Johnson JS | bioRxiv : the preprint server for biology | 38712059 | bioRxiv | 2024 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/38712059 |
Convergent mutations in phage virion assembly proteins enable evasion of Type I CBASS immunity. | Richmond-Buccola D, Hobbs SJ, Garcia JM, Toyoda H, Gao J, Shao S, Lee ASY, Kranzusch PJ | bioRxiv : the preprint server for biology | 37292831 | bioRxiv | 2023 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/37292831 |
The virus-induced cyclic dinucleotide 2'3'-c-di-GMP mediates STING-dependent antiviral immunity in Drosophila. | Cai H, Li L, Slavik KM, Huang J, Yin T, Ai X, Hédelin L, Haas G, Xiang Z, Yang Y, Li X, Chen Y, Wei Z, Deng H, Chen D, Jiao R, Martins N, Meignin C, Kranzusch PJ, Imler JL | Immunity | 37659413 | Immunity | 2023 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/37659413 |
A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense. | Chang RB, Toyoda HC, Hobbs SJ, Richmond-Buccola D, Wein T, Burger N, Chouchani ET, Sorek R, Kranzusch PJ | bioRxiv : the preprint server for biology | 39803557 | bioRxiv | 2024 Dec 31 | https://www.ncbi.nlm.nih.gov/pubmed/39803557 |
CARD-like domains mediate anti-phage defense in bacterial gasdermin systems. | Wein T, Johnson AG, Millman A, Lange K, Yirmiya E, Hadary R, Garb J, Steinruecke F, Hill AB, Kranzusch PJ, Sorek R | bioRxiv : the preprint server for biology | 37398489 | bioRxiv | 2023 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/37398489 |
Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases. | Mosallanejad K, Kennedy SN, Bahleda KM, Slavik KM, Zhou W, Govande AA, Hancks DC, Kranzusch PJ, Kagan JC | Science immunology | 36662885 | Sci Immunol | 2023 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/36662885 |
Structure and assembly of a bacterial gasdermin pore. | Johnson AG, Mayer ML, Schaefer SL, McNamara-Bordewick NK, Hummer G, Kranzusch PJ | Nature | 38509367 | Nature | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38509367 |
A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion. | Richmond-Buccola D, Hobbs SJ, Garcia JM, Toyoda H, Gao J, Shao S, Lee ASY, Kranzusch PJ | Cell host & microbe | 38917809 | Cell Host Microbe | 2024 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/38917809 |
Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing. | Scott TM, Arnold LM, Powers JA, McCann DA, Rowe AB, Christensen DE, Pereira MJ, Zhou W, Torrez RM, Iwasa JH, Kranzusch PJ, Sundquist WI, Johnson JS | PLoS pathogens | 39874383 | PLoS Pathog | 2025 Jan | https://www.ncbi.nlm.nih.gov/pubmed/39874383 |
Cryo-EM structure of an active bacterial TIR-STING filament complex. | Morehouse BR, Yip MCJ, Keszei AFA, McNamara-Bordewick NK, Shao S, Kranzusch PJ | Nature | 35859168 | Nature | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35859168 |
cGLRs are a diverse family of pattern recognition receptors in innate immunity. | Li Y, Slavik KM, Toyoda HC, Morehouse BR, de Oliveira Mann CC, Elek A, Levy S, Wang Z, Mears KS, Liu J, Kashin D, Guo X, Mass T, Sebé-Pedrós A, Schwede F, Kranzusch PJ | Cell | 37379839 | Cell | 2023 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/37379839 |
Viral sponges sequester nucleotide signals to inactivate immunity. | Richmond-Buccola D, Kranzusch PJ | Trends in microbiology | 37100632 | Trends Microbiol | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37100632 |
Structural basis of Gabija anti-phage defence and viral immune evasion. | Antine SP, Johnson AG, Mooney SE, Leavitt A, Mayer ML, Yirmiya E, Amitai G, Sorek R, Kranzusch PJ | Nature | 37992757 | Nature | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/37992757 |
Structure and assembly of a bacterial gasdermin pore. | Johnson AG, Mayer ML, Schaefer SL, McNamara-Bordewick NK, Hummer G, Kranzusch PJ | bioRxiv : the preprint server for biology | 37131678 | bioRxiv | 2023 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/37131678 |
Animal and bacterial viruses share conserved mechanisms of immune evasion. | Hobbs SJ, Nomburg J, Doudna JA, Kranzusch PJ | Cell | 39197447 | Cell | 2024 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/39197447 |
Design of Protein Segments and Peptides for Binding to Protein Targets. | Gupta S, Azadvari N, Hosseinzadeh P | Biodesign research | 37850124 | Biodes Res | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/37850124 |
Macrocyclic Octapeptide Binding and Inferences on Protein Substrate Binding to Histone Deacetylase 6. | Watson PR, Gupta S, Hosseinzadeh P, Brown BP, Baker D, Christianson DW | ACS chemical biology | 37027789 | ACS Chem Biol | 2023 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/37027789 |
CYCLICCAE: A CONFORMATIONAL AUTOENCODER FOR EFFICIENT HETEROCHIRAL MACROCYCLIC BACKBONE SAMPLING. | Powers AC, Renfrew PD, Hosseinzadeh P, Mulligan VK | bioRxiv : the preprint server for biology | 40060652 | bioRxiv | 2025 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/40060652 |
Strain-Inducing Positional Alkene Isomerization. | Palani V, Wendlandt AE | Journal of the American Chemical Society | 37647593 | J Am Chem Soc | 2023 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/37647593 |
Stereochemical editing logic powered by the epimerization of unactivated tertiary stereocenters. | Zhang YA, Palani V, Seim AE, Wang Y, Wang KJ, Wendlandt AE | Science (New York, N.Y.) | 36302032 | Science | 2022 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/36302032 |
Synthesis of non-canonical amino acids through dehydrogenative tailoring. | Gu X, Zhang YA, Zhang S, Wang L, Ye X, Occhialini G, Barbour J, Pentelute BL, Wendlandt AE | Nature | 39208846 | Nature | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39208846 |
A Change from Kinetic to Thermodynamic Control Enables trans-Selective Stereochemical Editing of Vicinal Diols. | Zhang YA, Gu X, Wendlandt AE | Journal of the American Chemical Society | 34928134 | J Am Chem Soc | 2022 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/34928134 |
Advancements in G protein-coupled receptor biosensors to study GPCR-G protein coupling. | Olsen RHJ, English JG | British journal of pharmacology | 36166832 | Br J Pharmacol | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/36166832 |
Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters. | Zahm AM, Owens WS, Himes SR, Rondem KE, Fallon BS, Gormick AN, Bloom JS, Kosuri S, Chan H, English JG | bioRxiv : the preprint server for biology | 37214829 | bioRxiv | 2023 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/37214829 |
A massively parallel reporter assay library to screen short synthetic promoters in mammalian cells. | Zahm AM, Owens WS, Himes SR, Fallon BS, Rondem KE, Gormick AN, Bloom JS, Kosuri S, Chan H, English JG | Nature communications | 39609378 | Nat Commun | 2024 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/39609378 |
Solid-Phase Compatible Silane-Based Cleavable Linker Enables Custom Isobaric Quantitative Chemoproteomics. | Burton NR, Polasky DA, Shikwana F, Ofori S, Yan T, Geiszler DJ, Veiga Leprevost FD, Nesvizhskii AI, Backus KM | Journal of the American Chemical Society | 37738129 | J Am Chem Soc | 2023 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/37738129 |
Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome. | Yan T, Julio AR, Villanueva M, Jones AE, Ball AB, Boatner LM, Turmon AC, Nguyễn KB, Yen SL, Desai HS, Divakaruni AS, Backus KM | Cell chemical biology | 37419112 | Cell Chem Biol | 2023 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/37419112 |
Chemoproteomics Identifies State-Dependent and Proteoform-Selective Caspase-2 Inhibitors. | Castellón JO, Ofori S, Burton NR, Julio AR, Turmon AC, Armenta E, Sandoval C, Boatner LM, Takayoshi EE, Faragalla M, Taylor C, Zhou AL, Tran K, Shek J, Yan T, Desai HS, Fregoso OI, Damoiseaux R, Backus KM | Journal of the American Chemical Society | 38787738 | J Am Chem Soc | 2024 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/38787738 |
Lipid- and protein-directed photosensitizer proximity labeling captures the cholesterol interactome. | Becker AP, Biletch E, Kennelly JP, Julio AR, Villaneuva M, Nagari RT, Turner DW, Burton NR, Fukuta T, Cui L, Xiao X, Hong SG, Mack JJ, Tontonoz P, Backus KM | bioRxiv : the preprint server for biology | 39229057 | bioRxiv | 2024 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/39229057 |
An activation-based high throughput screen identifies caspase-10 inhibitors. | Castellón JO, Yuen C, Han B, Andrews KH, Ofori S, Julio AR, Boatner LM, Palafox MF, Perumal N, Damoiseaux R, Backus KM | RSC chemical biology | 40013156 | RSC Chem Biol | 2025 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/40013156 |
Cholesterol binding to VCAM-1 promotes vascular inflammation. | Kennelly JP, Xiao X, Gao Y, Kim S, Hong SG, Villanueva M, Ferrari A, Vanharanta L, Nguyen A, Nagari RT, Burton NR, Tol MJ, Becker AP, Lee MJ, Ikonen E, Backus KM, Mack JJ, Tontonoz P | bioRxiv : the preprint server for biology | 39345495 | bioRxiv | 2024 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/39345495 |
Functionalizing tandem mass tags for streamlining click-based quantitative chemoproteomics. | Burton NR, Backus KM | Communications chemistry | 38600184 | Commun Chem | 2024 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/38600184 |
Delineating cysteine-reactive compound modulation of cellular proteostasis processes. | Julio AR, Shikwana F, Truong C, Burton NR, Dominguez ER 3rd, Turmon AC, Cao J, Backus KM | Nature chemical biology | 39448844 | Nat Chem Biol | 2024 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/39448844 |
Graph-based autoencoder integrates spatial transcriptomics with chromatin images and identifies joint biomarkers for Alzheimer's disease. | Zhang X, Wang X, Shivashankar GV, Uhler C | Nature communications | 36463283 | Nat Commun | 2022 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/36463283 |
Branched chemically modified poly(A) tails enhance the translation capacity of mRNA. | Chen H, Liu D, Guo J, Aditham A, Zhou Y, Tian J, Luo S, Ren J, Hsu A, Huang J, Kostas F, Wu M, Liu DR, Wang X | Nature biotechnology | 38519719 | Nat Biotechnol | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38519719 |
Spatial omics advances for in situ RNA biology. | Ren J, Luo S, Shi H, Wang X | Molecular cell | 39270643 | Mol Cell | 2024 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/39270643 |
ClusterMap for multi-scale clustering analysis of spatial gene expression. | He Y, Tang X, Huang J, Ren J, Zhou H, Chen K, Liu A, Shi H, Lin Z, Li Q, Aditham A, Ounadjela J, Grody EI, Shu J, Liu J, Wang X | Nature communications | 34625546 | Nat Commun | 2021 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/34625546 |
Spatially resolved single-cell translatomics at molecular resolution. | Zeng H, Huang J, Ren J, Wang CK, Tang Z, Zhou H, Zhou Y, Shi H, Aditham A, Sui X, Chen H, Lo JA, Wang X | Science (New York, N.Y.) | 37384709 | Science | 2023 Jun 30 | https://www.ncbi.nlm.nih.gov/pubmed/37384709 |
Multimodal charting of molecular and functional cell states via in situ electro-sequencing. | Li Q, Lin Z, Liu R, Tang X, Huang J, He Y, Sui X, Tian W, Shen H, Zhou H, Sheng H, Shi H, Xiao L, Wang X, Liu J | Cell | 37080201 | Cell | 2023 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/37080201 |
Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease. | Zeng H, Huang J, Zhou H, Meilandt WJ, Dejanovic B, Zhou Y, Bohlen CJ, Lee SH, Ren J, Liu A, Tang Z, Sheng H, Liu J, Sheng M, Wang X | Nature neuroscience | 36732642 | Nat Neurosci | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36732642 |
Spatiotemporally resolved transcriptomics reveals the subcellular RNA kinetic landscape. | Ren J, Zhou H, Zeng H, Wang CK, Huang J, Qiu X, Sui X, Li Q, Wu X, Lin Z, Lo JA, Maher K, He Y, Tang X, Lam J, Chen H, Li B, Fisher DE, Liu J, Wang X | Nature methods | 37038000 | Nat Methods | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37038000 |
Search and match across spatial omics samples at single-cell resolution. | Tang Z, Luo S, Zeng H, Huang J, Sui X, Wu M, Wang X | Nature methods | 39294367 | Nat Methods | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39294367 |
Diversity of ribosomes at the level of rRNA variation associated with human health and disease. | Rothschild D, Susanto TT, Sui X, Spence JP, Rangan R, Genuth NR, Sinnott-Armstrong N, Wang X, Pritchard JK, Barna M | bioRxiv : the preprint server for biology | 36778251 | bioRxiv | 2024 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/36778251 |
Spatial atlas of the mouse central nervous system at molecular resolution. | Shi H, He Y, Zhou Y, Huang J, Maher K, Wang B, Tang Z, Luo S, Tan P, Wu M, Lin Z, Ren J, Thapa Y, Tang X, Chan KY, Deverman BE, Shen H, Liu A, Liu J, Wang X | Nature | 37758947 | Nature | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37758947 |
Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocks. | Sui X, Lo JA, Luo S, He Y, Tang Z, Lin Z, Zhou Y, Wang WX, Liu J, Wang X | bioRxiv : the preprint server for biology | 39149316 | bioRxiv | 2024 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/39149316 |
Chemical and topological design of multicapped mRNA and capped circular RNA to augment translation. | Chen H, Liu D, Aditham A, Guo J, Huang J, Kostas F, Maher K, Friedrich MJ, Xavier RJ, Zhang F, Wang X | Nature biotechnology | 39313647 | Nat Biotechnol | 2024 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/39313647 |
Live cell single-molecule imaging to study DNA repair in human cells. | Heyza JR, Mikhova M, Schmidt JC | DNA repair | 37467632 | DNA Repair (Amst) | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37467632 |
Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates. | Broadbent DG, McEwan CM, Jayatunge D, Kaminsky EG, Tsang TM, Poole DM, Naylor BC, Price JC, Schmidt JC, Andersen JL | Molecular biology of the cell | 39718773 | Mol Biol Cell | 2025 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/39718773 |
TRF1 and TRF2 form distinct shelterin subcomplexes at telomeres. | Janovič T, Perez GI, Schmidt JC | bioRxiv : the preprint server for biology | 39763972 | bioRxiv | 2024 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/39763972 |
The PST repeat region of MDC1 is a tunable multivalent chromatin tethering domain. | Heyza JR, Mikhova M, Perez GI, Broadbent DG, Schmidt JC | bioRxiv : the preprint server for biology | 39868091 | bioRxiv | 2025 Jan 13 | https://www.ncbi.nlm.nih.gov/pubmed/39868091 |
Systematic analysis of the molecular and biophysical properties of key DNA damage response factors. | Heyza JR, Mikhova M, Bahl A, Broadbent DG, Schmidt JC | eLife | 37341699 | Elife | 2023 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/37341699 |
The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy. | Broadbent DG, McEwan CM, Tsang TM, Poole DM, Naylor BC, Price JC, Schmidt JC, Andersen JL | bioRxiv : the preprint server for biology | 38077022 | bioRxiv | 2023 Nov 29 | https://www.ncbi.nlm.nih.gov/pubmed/38077022 |
RHINO restricts MMEJ activity to mitosis. | Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A | bioRxiv : the preprint server for biology | 36993461 | bioRxiv | 2023 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/36993461 |
PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress. | Mashayekhi F, Ganje C, Caron MC, Heyza JR, Gao Y, Zeinali E, Fanta M, Li L, Ali J, Mersaoui SY, Schmidt JC, Godbout R, Masson JY, Weinfeld M, Ismail IH | Cell reports | 39671289 | Cell Rep | 2024 Dec 24 | https://www.ncbi.nlm.nih.gov/pubmed/39671289 |
Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation. | Broadbent DG, Barnaba C, Perez GI, Schmidt JC | The Journal of cell biology | 37115157 | J Cell Biol | 2023 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/37115157 |
Tracking the transition from an ATG9A vesicle to an autophagosome. | Broadbent D, Barnaba C, Schmidt JC | Autophagy | 37405380 | Autophagy | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37405380 |
RHINO directs MMEJ to repair DNA breaks in mitosis. | Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A | Science (New York, N.Y.) | 37440612 | Science | 2023 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/37440612 |
Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells. | Mikhova M, Goff NJ, Janovič T, Heyza JR, Meek K, Schmidt JC | Nature communications | 39578493 | Nat Commun | 2024 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/39578493 |
AMPK regulates phagophore-to-autophagosome maturation. | Barnaba C, Broadbent DG, Kaminsky EG, Perez GI, Schmidt JC | The Journal of cell biology | 38775785 | J Cell Biol | 2024 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/38775785 |
AMPK Regulates Phagophore-to-Autophagosome Maturation. | Barnaba C, Broadbent DG, Perez GI, Schmidt JC | bioRxiv : the preprint server for biology | 37808644 | bioRxiv | 2023 Sep 30 | https://www.ncbi.nlm.nih.gov/pubmed/37808644 |
Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells. | Mikhova M, Goff NJ, Janovič T, Heyza JR, Meek K, Schmidt JC | bioRxiv : the preprint server for biology | 38826211 | bioRxiv | 2024 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/38826211 |
Native SAD phasing at room temperature. | Greisman JB, Dalton KM, Sheehan CJ, Klureza MA, Kurinov I, Hekstra DR | Acta crystallographica. Section D, Structural biology | 35916223 | Acta Crystallogr D Struct Biol | 2022 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/35916223 |
Correcting systematic errors in diffraction data with modern scaling algorithms. | Aldama LA, Dalton KM, Hekstra DR | Acta crystallographica. Section D, Structural biology | 37584427 | Acta Crystallogr D Struct Biol | 2023 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/37584427 |
Insights into VDAC Gating: Room-Temperature X-ray Crystal Structure of mVDAC-1. | Gonzalez-DeWhitt KR, Ermolova N, Wang HK, Hekstra DR, Althoff T, Abramson J | Biomolecules | 39456136 | Biomolecules | 2024 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/39456136 |
Resolving DJ-1 Glyoxalase Catalysis Using Mix-and-Inject Serial Crystallography at a Synchrotron. | Zielinski KA, Dolamore C, Dalton KM, Smith N, Termini J, Henning R, Srajer V, Hekstra DR, Pollack L, Wilson MA | bioRxiv : the preprint server for biology | 39071394 | bioRxiv | 2024 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/39071394 |
MatchMaps: non-isomorphous difference maps for X-ray crystallography. | Brookner DE, Hekstra DR | Journal of applied crystallography | 38846758 | J Appl Crystallogr | 2024 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/38846758 |
Scaling and Merging Time-Resolved Laue Data with Variational Inference. | Zielinski KA, Dolamore C, Wang HK, Henning RW, Wilson MA, Pollack L, Srajer V, Hekstra DR, Dalton KM | bioRxiv : the preprint server for biology | 39131362 | bioRxiv | 2024 Jul 31 | https://www.ncbi.nlm.nih.gov/pubmed/39131362 |
Mapping protein conformational landscapes from crystallographic drug fragment screens. | Saeed AA, Klureza MA, Hekstra DR | bioRxiv : the preprint server for biology | 39131376 | bioRxiv | 2024 Jul 30 | https://www.ncbi.nlm.nih.gov/pubmed/39131376 |
Scaling and merging time-resolved pink-beam diffraction with variational inference. | Zielinski KA, Dolamore C, Wang HK, Henning RW, Wilson MA, Pollack L, Srajer V, Hekstra DR, Dalton KM | Structural dynamics (Melville, N.Y.) | 39629168 | Struct Dyn | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39629168 |
Mapping Protein Conformational Landscapes from Crystallographic Drug Fragment Screens. | Saeed AA, Klureza MA, Hekstra DR | Journal of chemical information and modeling | 39530154 | J Chem Inf Model | 2024 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/39530154 |
AlphaFold as a Prior: Experimental Structure Determination Conditioned on a Pretrained Neural Network. | Fadini A, Li M, McCoy AJ, Terwilliger TC, Read RJ, Hekstra D, AlQuraishi M | bioRxiv : the preprint server for biology | 40027838 | bioRxiv | 2025 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/40027838 |
SFCalculator: connecting deep generative models and crystallography. | Li M, Dalton K, Hekstra D | bioRxiv : the preprint server for biology | 39868231 | bioRxiv | 2025 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/39868231 |
Laue-DIALS: open-source software for polychromatic X-ray diffraction data. | Hewitt RA, Dalton KM, Mendez D, Wang HK, Klureza MA, Brookner DE, Greisman JB, McDonagh D, Šrajer V, Sauter NK, Brewster AS, Hekstra DR | bioRxiv : the preprint server for biology | 39091818 | bioRxiv | 2024 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/39091818 |
Sensitive Detection of Structural Differences using a Statistical Framework for Comparative Crystallography. | Hekstra DR, Wang HK, Klureza MA, Greisman JB, Dalton KM | bioRxiv : the preprint server for biology | 39091831 | bioRxiv | 2024 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/39091831 |
Resolving conformational changes that mediate a two-step catalytic mechanism in a model enzyme. | Greisman JB, Dalton KM, Brookner DE, Klureza MA, Sheehan CJ, Kim IS, Henning RW, Russi S, Hekstra DR | bioRxiv : the preprint server for biology | 37398233 | bioRxiv | 2023 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/37398233 |
A unifying Bayesian framework for merging X-ray diffraction data. | Dalton KM, Greisman JB, Hekstra DR | Nature communications | 36522310 | Nat Commun | 2022 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/36522310 |
MatchMaps: Non-isomorphous difference maps for X-ray crystallography. | Brookner DE, Hekstra DR | bioRxiv : the preprint server for biology | 37732267 | bioRxiv | 2024 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/37732267 |
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. | Greisman JB, Dalton KM, Brookner DE, Klureza MA, Sheehan CJ, Kim IS, Henning RW, Russi S, Hekstra DR | Proceedings of the National Academy of Sciences of the United States of America | 38386706 | Proc Natl Acad Sci U S A | 2024 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/38386706 |
Laue-DIALS: Open-source software for polychromatic x-ray diffraction data. | Hewitt RA, Dalton KM, Mendez DA, Wang HK, Klureza MA, Brookner DE, Greisman JB, McDonagh D, Šrajer V, Sauter NK, Brewster AS, Hekstra DR | Structural dynamics (Melville, N.Y.) | 39386198 | Struct Dyn | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39386198 |
Emerging Time-Resolved X-Ray Diffraction Approaches for Protein Dynamics. | Hekstra DR | Annual review of biophysics | 37159292 | Annu Rev Biophys | 2023 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/37159292 |
Direct visualization of electric-field-stimulated ion conduction in a potassium channel. | Lee B, White KI, Socolich M, Klureza MA, Henning R, Srajer V, Ranganathan R, Hekstra DR | Cell | 39793560 | Cell | 2025 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/39793560 |
Noncoding translation mitigation. | Kesner JS, Chen Z, Shi P, Aparicio AO, Murphy MR, Guo Y, Trehan A, Lipponen JE, Recinos Y, Myeku N, Wu X | Nature | 37046090 | Nature | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37046090 |
Finding functional microproteins. | Azam S, Yang F, Wu X | Trends in genetics : TIG | 39753408 | Trends Genet | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39753408 |
Collateral activity of the CRISPR/RfxCas13d system in human cells. | Shi P, Murphy MR, Aparicio AO, Kesner JS, Fang Z, Chen Z, Trehan A, Guo Y, Wu X | Communications biology | 36977923 | Commun Biol | 2023 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/36977923 |
Programmable RNA targeting with CRISPR-Cas13. | Shi P, Wu X | RNA biology | 38764173 | RNA Biol | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/38764173 |
Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments. | Goel VY, Huseyin MK, Hansen AS | Nature genetics | 37157000 | Nat Genet | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37157000 |
Enhancer selectivity in space and time: from enhancer-promoter interactions to promoter activation. | Yang JH, Hansen AS | Nature reviews. Molecular cell biology | 38413840 | Nat Rev Mol Cell Biol | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38413840 |
Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation. | Kim KL, Rahme GJ, Goel VY, El Farran CA, Hansen AS, Bernstein BE | Molecular cell | 38452764 | Mol Cell | 2024 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/38452764 |
Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging. | Mahadevan J, Jha A, Rudolph J, Bowerman S, Narducci D, Hansen AS, Luger K | iScience | 36594010 | iScience | 2023 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/36594010 |
LDB1 establishes multi-enhancer networks to regulate gene expression. | Aboreden NG, Lam JC, Goel VY, Wang S, Wang X, Midla SC, Quijano A, Keller CA, Giardine BM, Hardison RC, Zhang H, Hansen AS, Blobel GA | bioRxiv : the preprint server for biology | 39229045 | bioRxiv | 2024 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/39229045 |
Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project. | Dekker J, Alber F, Aufmkolk S, Beliveau BJ, Bruneau BG, Belmont AS, Bintu L, Boettiger A, Calandrelli R, Disteche CM, Gilbert DM, Gregor T, Hansen AS, Huang B, Huangfu D, Kalhor R, Leslie CS, Li W, Li Y, Ma J, Noble WS, Park PJ, Phillips-Cremins JE, Pollard KS, Rafelski SM, Ren B, Ruan Y, Shav-Tal Y, Shen Y, Shendure J, Shu X, Strambio-De-Castillia C, Vertii A, Zhang H, Zhong S | Molecular cell | 37419111 | Mol Cell | 2023 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/37419111 |
Molecular models of bidirectional promoter regulation. | Nemsick S, Hansen AS | Current opinion in structural biology | 38905929 | Curr Opin Struct Biol | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38905929 |
Integrative PTEN Enhancer Discovery Reveals a New Model of Enhancer Organization. | Cerda-Smith CG, Hutchinson HM, Liu A, Goel VY, Sept C, Kim H, Casaní-Galdón S, Burkman KG, Bassil CF, Hansen AS, Aryee MJ, Johnstone SE, Eyler CE, Wood KC | bioRxiv : the preprint server for biology | 37786671 | bioRxiv | 2023 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/37786671 |
An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing. | Waterbury AL, Kwok HS, Lee C, Narducci DN, Freedy AM, Su C, Raval S, Reiter AH, Hawkins W, Lee K, Li J, Hoenig SM, Vinyard ME, Cole PA, Hansen AS, Carr SA, Papanastasiou M, Liau BB | Molecular cell | 38870936 | Mol Cell | 2024 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/38870936 |
Tracking and interpreting long-range chromatin interactions with super-resolution live-cell imaging. | Brandão HB, Gabriele M, Hansen AS | Current opinion in cell biology | 33310227 | Curr Opin Cell Biol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33310227 |
Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging. | Gabriele M, Brandão HB, Grosse-Holz S, Jha A, Dailey GM, Cattoglio C, Hsieh TS, Mirny L, Zechner C, Hansen AS | Science (New York, N.Y.) | 35420890 | Science | 2022 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/35420890 |
Reeling it in: how DNA topology drives loop extrusion by condensin. | Narducci DN, Hansen AS | Nature structural & molecular biology | 35835869 | Nat Struct Mol Biol | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35835869 |
Genome-wide absolute quantification of chromatin looping. | Jusuf JM, Grosse-Holz S, Gabriele M, Mach P, Flyamer IM, Zechner C, Giorgetti L, Mirny LA, Hansen AS | bioRxiv : the preprint server for biology | 39935886 | bioRxiv | 2025 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/39935886 |
Enhancer-promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1. | Hsieh TS, Cattoglio C, Slobodyanyuk E, Hansen AS, Darzacq X, Tjian R | Nature genetics | 36471071 | Nat Genet | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36471071 |
A Protocol for Studying Transcription Factor Dynamics Using Fast Single-Particle Tracking and Spot-On Model-Based Analysis. | Jha A, Hansen AS | Methods in molecular biology (Clifton, N.J.) | 35103967 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35103967 |
Promoters adopt distinct dynamic manifestations depending on transcription factor context. | Hansen AS, Zechner C | Molecular systems biology | 33595925 | Mol Syst Biol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33595925 |
DNA double-strand break end synapsis by DNA loop extrusion. | Yang JH, Brandão HB, Hansen AS | Nature communications | 37024496 | Nat Commun | 2023 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/37024496 |
Right on target: Chromatin jets arise from targeted cohesin loading in wild-type cells. | Drayton JA, Hansen AS | Molecular cell | 36270244 | Mol Cell | 2022 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/36270244 |
Dynamics of microcompartment formation at the mitosis-to-G1 transition. | Goel VY, Aboreden NG, Jusuf JM, Zhang H, Mori LP, Mirny LA, Blobel GA, Banigan EJ, Hansen AS | bioRxiv : the preprint server for biology | 39345388 | bioRxiv | 2024 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/39345388 |
Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS. | Robertson WE, Funke LFH, de la Torre D, Fredens J, Wang K, Chin JW | Nature protocols | 33903757 | Nat Protoc | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33903757 |
Genome manipulation by guide-directed Argonaute cleavage. | Huang S, Wang K, Mayo SL | Nucleic acids research | 36928676 | Nucleic Acids Res | 2023 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/36928676 |
Removal of Antibiotic Resistant Bacteria and Genes by UV-Assisted Electrochemical Oxidation on Degenerative TiO(2) Nanotube Arrays. | Wang S, Yang S, Quispe E, Yang H, Sanfiorenzo C, Rogers SW, Wang K, Yang Y, Hoffmann MR | ACS ES&T engineering | 39605952 | ACS ES T Eng | 2021 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/39605952 |
Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation. | Kim TE, Tsuboyama K, Houliston S, Martell CM, Phoumyvong CM, Lemak A, Haddox HK, Arrowsmith CH, Rocklin GJ | Proceedings of the National Academy of Sciences of the United States of America | 36191185 | Proc Natl Acad Sci U S A | 2022 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/36191185 |
Structural and energetic analysis of stabilizing indel mutations. | Gutierrez YM, Rocklin GJ | bioRxiv : the preprint server for biology | 39763793 | bioRxiv | 2024 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/39763793 |
Intracellular Formation of a DNA Damage-Induced, Histone Post-Translational Modification Following Bleomycin Treatment. | Jacinto MP, Fried SD, Greenberg MM | Journal of the American Chemical Society | 35467863 | J Am Chem Soc | 2022 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/35467863 |
Universal protein misfolding intermediates can bypass the proteostasis network and remain soluble and less functional. | Nissley DA, Jiang Y, Trovato F, Sitarik I, Narayan KB, To P, Xia Y, Fried SD, O'Brien EP | Nature communications | 35654797 | Nat Commun | 2022 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/35654797 |
Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state. | Nodelman IM, Das S, Faustino AM, Fried SD, Bowman GD, Armache JP | Nature structural & molecular biology | 35173352 | Nat Struct Mol Biol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35173352 |
Progress toward Proteome-Wide Photo-Cross-Linking to Enable Residue-Level Visualization of Protein Structures and Networks In Vivo. | Faustino AM, Sharma P, Manriquez-Sandoval E, Yadav D, Fried SD | Analytical chemistry | 37341467 | Anal Chem | 2023 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/37341467 |
Early Selection of the Amino Acid Alphabet Was Adaptively Shaped by Biophysical Constraints of Foldability. | Makarov M, Sanchez Rocha AC, Krystufek R, Cherepashuk I, Dzmitruk V, Charnavets T, Faustino AM, Lebl M, Fujishima K, Fried SD, Hlouchova K | Journal of the American Chemical Society | 36826345 | J Am Chem Soc | 2023 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/36826345 |
Cryo-EM structures of the Plant Augmin reveal its intertwined coiled-coil assembly, antiparallel dimerization and NEDD1 binding mechanisms. | Ashaduzzaman M, Taheri A, Lee YJ, Tang Y, Guo F, Fried SD, Liu B, Al-Bassam J | bioRxiv : the preprint server for biology | 40034650 | bioRxiv | 2025 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/40034650 |
FLiPPR: A Processor for Limited Proteolysis (LiP) Mass Spectrometry Datasets Built on FragPipe. | Manriquez-Sandoval E, Brewer J, Lule G, Lopez S, Fried SD | bioRxiv : the preprint server for biology | 38106106 | bioRxiv | 2023 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/38106106 |
Nonrefoldability is Pervasive Across the E. coli Proteome. | To P, Whitehead B, Tarbox HE, Fried SD | Journal of the American Chemical Society | 34308638 | J Am Chem Soc | 2021 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/34308638 |
A proteome-wide map of chaperone-assisted protein refolding in a cytosol-like milieu. | To P, Xia Y, Lee SO, Devlin T, Fleming KG, Fried SD | Proceedings of the National Academy of Sciences of the United States of America | 36417429 | Proc Natl Acad Sci U S A | 2022 Nov 29 | https://www.ncbi.nlm.nih.gov/pubmed/36417429 |
Synonymous Mutations Can Alter Protein Dimerization Through Localized Interface Misfolding Involving Self-entanglements. | Lan PD, Nissley DA, Sitarik I, Vu QV, Jiang Y, To P, Xia Y, Fried SD, Li MS, O'Brien EP | Journal of molecular biology | 38341172 | J Mol Biol | 2024 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/38341172 |
How synonymous mutations alter enzyme structure and function over long timescales. | Jiang Y, Neti SS, Sitarik I, Pradhan P, To P, Xia Y, Fried SD, Booker SJ, O'Brien EP | Nature chemistry | 36471044 | Nat Chem | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36471044 |
Secretion-Catalyzed Assembly of Protein Biomaterials on a Bacterial Membrane Surface. | Xie Q, On Lee S, Vissamsetti N, Guo S, Johnson ME, Fried SD | Angewandte Chemie (International ed. in English) | 37469298 | Angew Chem Int Ed Engl | 2023 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/37469298 |
Cognition-Associated Protein Structural Changes in a Rat Model of Aging are Related to Reduced Refolding Capacity. | Tarbox HE, Branch A, Fried SD | bioRxiv : the preprint server for biology | 39386726 | bioRxiv | 2024 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/39386726 |
FLiPPR: A Processor for Limited Proteolysis (LiP) Mass Spectrometry Data Sets Built on FragPipe. | Manriquez-Sandoval E, Brewer J, Lule G, Lopez S, Fried SD | Journal of proteome research | 38787630 | J Proteome Res | 2024 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/38787630 |
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq. | Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS | Cell | 35688146 | Cell | 2022 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/35688146 |
Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome. | Metzner E, Southard KM, Norman TM | bioRxiv : the preprint server for biology | 39091800 | bioRxiv | 2024 Jul 27 | https://www.ncbi.nlm.nih.gov/pubmed/39091800 |
Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome. | Metzner E, Southard KM, Norman TM | Cell systems | 39689711 | Cell Syst | 2025 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/39689711 |
Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states. | Southard KM, Ardy RC, Tang A, O'Sullivan DD, Metzner E, Guruvayurappan K, Norman TM | bioRxiv : the preprint server for biology | 39131349 | bioRxiv | 2024 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/39131349 |
Decoding the function and regulation of the mammalian 12-h clock. | Zhu B | Journal of molecular cell biology | 32384155 | J Mol Cell Biol | 2020 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/32384155 |
Preservation of ∼12-h ultradian rhythms of gene expression of mRNA and protein metabolism in the absence of canonical circadian clock. | Zhu B, Liu S | Frontiers in physiology | 37324401 | Front Physiol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37324401 |
Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism. | Meng H, Gonzales NM, Jung SY, Lu Y, Putluri N, Zhu B, Dacso CC, Lonard DM, O'Malley BW | Cell reports | 35263593 | Cell Rep | 2022 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/35263593 |
Beyond circadian rhythms: emerging roles of ultradian rhythms in control of liver functions. | Asher G, Zhu B | Hepatology (Baltimore, Md.) | 35591797 | Hepatology | 2023 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/35591797 |
LEF1 isoforms regulate cellular senescence and aging. | Jia M, Sayed K, Kapetanaki MG, Dion W, Rosas L, Irfan S, Valenzi E, Mora AL, Lafyatis RA, Rojas M, Zhu B, Benos PV | bioRxiv : the preprint server for biology | 37502913 | bioRxiv | 2023 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/37502913 |
LEF1 isoforms regulate cellular senescence and aging. | Jia M, Sayed K, Kapetanaki MG, Dion W, Rosas L, Irfan S, Valenzi E, Mora AL, Lafyatis RA, Rojas M, Zhu B, Benos PV | Aging cell | 37961030 | Aging Cell | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37961030 |
Preservation of ∼12-hour ultradian rhythms of gene expression of mRNA and protein metabolism in the absence of canonical circadian clock. | Zhu B, Liu S | bioRxiv : the preprint server for biology | 37205336 | bioRxiv | 2023 May 2 | https://www.ncbi.nlm.nih.gov/pubmed/37205336 |
Evidence for conservation of primordial ~12-hour ultradian gene programs in humans under free-living conditions. | Zhu B, Liu S, David NL, Dion W, Doshi NK, Siegel LB, Amorim T, Andrews RE, Naveen Kumar GV, Li H, Irfan S, Pesaresi T, Sharma AX, Sun M, Fazeli PK, Steinhauser ML | bioRxiv : the preprint server for biology | 37205600 | bioRxiv | 2023 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/37205600 |
Epigenetic regulation of global proteostasis dynamics by RBBP5 ensures mammalian organismal health. | Kubra S, Sun M, Dion W, Catak A, Luong H, Wang H, Pan Y, Liu JJ, Ponna A, Sipula I, Jurczak MJ, Liu S, Zhu B | bioRxiv : the preprint server for biology | 39314427 | bioRxiv | 2024 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/39314427 |
XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis. | Meng H, Gonzales NM, Lonard DM, Putluri N, Zhu B, Dacso CC, York B, O'Malley BW | Nature communications | 33277471 | Nat Commun | 2020 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/33277471 |
Revealing the hidden reality of the mammalian 12-h ultradian rhythms. | Ballance H, Zhu B | Cellular and molecular life sciences : CMLS | 33449146 | Cell Mol Life Sci | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33449146 |
Four-dimensional nuclear speckle phase separation dynamics regulate proteostasis. | Dion W, Ballance H, Lee J, Pan Y, Irfan S, Edwards C, Sun M, Zhang J, Zhang X, Liu S, Zhu B | Science advances | 34985945 | Sci Adv | 2022 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/34985945 |
Logic of the Temporal Compartmentalization of the Hepatic Metabolic Cycle. | Zhu B | Physiology (Bethesda, Md.) | 35658626 | Physiology (Bethesda) | 2022 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/35658626 |
Evidence for ~12-h ultradian gene programs in humans. | Zhu B, Liu S, David NL, Dion W, Doshi NK, Siegel LB, Amorim T, Andrews RE, Kumar GVN, Li H, Irfan S, Pesaresi T, Sharma AX, Sun M, Fazeli PK, Steinhauser ML | Npj biological timing and sleep | 39148626 | NPJ Biol Timing Sleep | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/39148626 |
Twelve-hour rhythms in transcript expression within the human dorsolateral prefrontal cortex are altered in schizophrenia. | Scott MR, Zong W, Ketchesin KD, Seney ML, Tseng GC, Zhu B, McClung CA | PLoS biology | 36693045 | PLoS Biol | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36693045 |
Temporal gene expression patterns in the coral Euphyllia paradivisa reveal the complexity of biological clocks in the cnidarian-algal symbiosis. | Rinsky M, Weizman E, Ben-Asher HW, Eyal G, Zhu B, Levy O | Science advances | 36112690 | Sci Adv | 2022 Sep 16 | https://www.ncbi.nlm.nih.gov/pubmed/36112690 |
SON-dependent nuclear speckle rejuvenation alleviates proteinopathies. | Dion W, Tao Y, Chambers M, Zhao S, Arbuckle RK, Sun M, Kubra S, Jamal I, Nie Y, Ye M, Larsen MB, Camarco D, Ickes E, DuPont C, Wang H, Wang B, Liu S, Pi S, Chen BB, Chen Y, Chen X, Zhu B | bioRxiv : the preprint server for biology | 38659924 | bioRxiv | 2024 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/38659924 |
Structural imaging studies of patients with chronic pain: an anatomical likelihood estimate meta-analysis. | Henn AT, Larsen B, Frahm L, Xu A, Adebimpe A, Scott JC, Linguiti S, Sharma V, Basbaum AI, Corder G, Dworkin RH, Edwards RR, Woolf CJ, Habel U, Eickhoff SB, Eickhoff CR, Wagels L, Satterthwaite TD | Pain | 35560117 | Pain | 2023 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/35560117 |
Engineered serum markers for non-invasive monitoring of gene expression in the brain. | Lee S, Nouraein S, Kwon JJ, Huang Z, Wojick JA, Xia B, Corder G, Szablowski JO | Nature biotechnology | 38200117 | Nat Biotechnol | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/38200117 |
Psilocybin-enhanced fear extinction linked to bidirectional modulation of cortical ensembles. | Rogers SA, Heller EA, Corder G | bioRxiv : the preprint server for biology | 38352491 | bioRxiv | 2024 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/38352491 |
Engaging endogenous opioid circuits in pain affective processes. | Kimmey BA, McCall NM, Wooldridge LM, Satterthwaite TD, Corder G | Journal of neuroscience research | 33314372 | J Neurosci Res | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33314372 |
Mimicking opioid analgesia in cortical pain circuits. | James JG, McCall NM, Hsu AI, Oswell CS, Salimando GJ, Mahmood M, Wooldridge LM, Wachira M, Jo A, Sandoval Ortega RA, Wojick JA, Beattie K, Farinas SA, Chehimi SN, Rodrigues A, Ejoh LL, Kimmey BA, Lo E, Azouz G, Vasquez JJ, Banghart MR, Creasy KT, Beier KT, Ramakrishnan C, Crist RC, Reiner BC, Deisseroth K, Yttri EA, Corder G | bioRxiv : the preprint server for biology | 38746090 | bioRxiv | 2024 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/38746090 |
Convergent state-control of endogenous opioid analgesia. | Kimmey BA, Ejoh L, Shangloo L, Wojick JA, Chehimi SN, McCall NM, Oswell CS, Mahmood M, Yang L, Samineni VK, Ramakrishnan C, Deisseroth K, Crist RC, Reiner BC, Tian L, Corder G | bioRxiv : the preprint server for biology | 39803541 | bioRxiv | 2025 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/39803541 |
Editorial: Broadening our conceptual understanding of endogenous opioids in systems neuroscience. | Tejeda HA, Massaly N, Corder G, Cahill CM | Frontiers in systems neuroscience | 37383356 | Front Syst Neurosci | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37383356 |
Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types. | Salimando GJ, Tremblay S, Kimmey BA, Li J, Rogers SA, Wojick JA, McCall NM, Wooldridge LM, Rodrigues A, Borner T, Gardiner KL, Jayakar SS, Singeç I, Woolf CJ, Hayes MR, De Jonghe BC, Bennett FC, Bennett ML, Blendy JA, Platt ML, Creasy KT, Renthal WR, Ramakrishnan C, Deisseroth K, Corder G | Nature communications | 37704594 | Nat Commun | 2023 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/37704594 |
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis. | Key FM, Khadka VD, Romo-González C, Blake KJ, Deng L, Lynn TC, Lee JC, Chiu IM, García-Romero MT, Lieberman TD | Cell host & microbe | 37054679 | Cell Host Microbe | 2023 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/37054679 |
Previously hidden intraspecies dynamics underlie the apparent stability of two important skin microbiome species. | Baker JS, Qu E, Mancuso CP, Tripp AD, Conwill A, Lieberman TD | bioRxiv : the preprint server for biology | 38260404 | bioRxiv | 2025 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/38260404 |
De novo mutations mediate phenotypic switching in an opportunistic human lung pathogen. | Poret AJ, Schaefers M, Merakou C, Mansour KE, Lagoudas GK, Cross AR, Goldberg JB, Kishony R, Uluer AZ, McAdam AJ, Blainey PC, Vargas SO, Lieberman TD, Priebe GP | bioRxiv : the preprint server for biology | 38370793 | bioRxiv | 2024 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/38370793 |
Intraspecies associations from strain-rich metagenome samples. | Qu EB, Baker JS, Markey L, Khadka V, Mancuso C, Tripp D, Lieberman TD | bioRxiv : the preprint server for biology | 39974997 | bioRxiv | 2025 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/39974997 |
Detecting bacterial adaptation within individual microbiomes. | Lieberman TD | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 35989602 | Philos Trans R Soc Lond B Biol Sci | 2022 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/35989602 |
Intraspecies warfare restricts strain coexistence in human skin microbiomes. | Mancuso CP, Baker JS, Qu E, Tripp AD, Balogun IO, Lieberman TD | bioRxiv : the preprint server for biology | 38765968 | bioRxiv | 2025 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/38765968 |
Anatomy promotes neutral coexistence of strains in the human skin microbiome. | Conwill A, Kuan AC, Damerla R, Poret AJ, Baker JS, Tripp AD, Alm EJ, Lieberman TD | Cell host & microbe | 34995483 | Cell Host Microbe | 2022 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/34995483 |
Reversions mask the contribution of adaptive evolution in microbiomes. | Torrillo PA, Lieberman TD | bioRxiv : the preprint server for biology | 37745437 | bioRxiv | 2024 Jun 18 | https://www.ncbi.nlm.nih.gov/pubmed/37745437 |
Reversions mask the contribution of adaptive evolution in microbiomes. | Torrillo PA, Lieberman TD | eLife | 39240756 | Elife | 2024 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/39240756 |
Demonstration of diamond nuclear spin gyroscope. | Jarmola A, Lourette S, Acosta VM, Birdwell AG, Blümler P, Budker D, Ivanov T, Malinovsky VS | Science advances | 34678066 | Sci Adv | 2021 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/34678066 |
Super-Resolution Diamond Magnetic Microscopy of Superparamagnetic Nanoparticles. | Mosavian N, Hubert F, Smits J, Kehayias P, Silani Y, Richards BA, Acosta VM | ACS nano | 38369724 | ACS Nano | 2024 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/38369724 |
Temperature Sensitivity of (14)N-V and (15)N-V Ground-State Manifolds. | Lourette S, Jarmola A, Acosta VM, Birdwell AG, Budker D, Doherty MW, Ivanov T, Malinovsky VS | Physical review applied | 38716475 | Phys Rev Appl | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38716475 |
Nuclear quadrupole resonance spectroscopy with a femtotesla diamond magnetometer. | Silani Y, Smits J, Fescenko I, Malone MW, McDowell AF, Jarmola A, Kehayias P, Richards BA, Mosavian N, Ristoff N, Acosta VM | Science advances | 37327342 | Sci Adv | 2023 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/37327342 |
The complexin C-terminal amphipathic helix stabilizes the fusion pore open state by sculpting membranes. | Courtney KC, Wu L, Mandal T, Swift M, Zhang Z, Alaghemandi M, Wu Z, Bradberry MM, Deo C, Lavis LD, Volkmann N, Hanein D, Cui Q, Bao H, Chapman ER | Nature structural & molecular biology | 35132256 | Nat Struct Mol Biol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35132256 |
Energetics, kinetics, and pathways of SNARE assembly in membrane fusion. | Zhang Y, Ma L, Bao H | Critical reviews in biochemistry and molecular biology | 36151854 | Crit Rev Biochem Mol Biol | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/36151854 |
Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors. | Xiong X, Tian S, Yang P, Lebreton F, Bao H, Sheng K, Yin L, Chen P, Zhang J, Qi W, Ruan J, Wu H, Chen H, Breault DT, Wu H, Earl AM, Gilmore MS, Abraham J, Dong M | Cell | 35259335 | Cell | 2022 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/35259335 |
Circularized fluorescent nanodiscs for probing protein-lipid interactions. | Ren Q, Zhang S, Bao H | Communications biology | 35618817 | Commun Biol | 2022 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/35618817 |
Targeting Recycling Endosomes to Potentiate mRNA Lipid Nanoparticles. | Shin J, Douglas CJ, Zhang S, Seath CP, Bao H | Nano letters | 38640421 | Nano Lett | 2024 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/38640421 |
DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides. | Ren Q, Wang J, Idikuda V, Zhang S, Shin J, Ludlam WG, Real Hernandez LM, Levental I, Martemyanov K, Chanda B, Bao H | bioRxiv : the preprint server for biology | 39574650 | bioRxiv | 2024 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/39574650 |
Developing Nanodisc-ID for label-free characterizations of membrane proteins. | Bao H | Communications biology | 33931748 | Commun Biol | 2021 Apr 30 | https://www.ncbi.nlm.nih.gov/pubmed/33931748 |
One-step construction of circularized nanodiscs using SpyCatcher-SpyTag. | Zhang S, Ren Q, Novick SJ, Strutzenberg TS, Griffin PR, Bao H | Nature communications | 34521837 | Nat Commun | 2021 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/34521837 |
Designer Nanodiscs to Probe and Reprogram Membrane Biology in Synapses. | Dallo S, Shin J, Zhang S, Ren Q, Bao H | Journal of molecular biology | 35872069 | J Mol Biol | 2023 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/35872069 |
High spatial-resolution imaging of label-free in vivo protein aggregates by VISTA. | Lin LE , Miao K , Qian C , Wei L | The Analyst | 33949430 | Analyst | 2021 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/33949430 |
Computational Design of Molecular Probes for Electronic Preresonance Raman Scattering Microscopy. | Du J, Tao X, Begušić T, Wei L | The journal of physical chemistry. B | 37226966 | J Phys Chem B | 2023 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/37226966 |
Bringing Vibrational Imaging to Chemical Biology with Molecular Probes. | Du J, Wang H, Wei L | ACS chemical biology | 35772040 | ACS Chem Biol | 2022 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/35772040 |
Seeing is Believing: Developing Multimodal Metabolic Insights at the Molecular Level. | Chadha RS, Guerrero JA, Wei L, Sanchez LM | ACS central science | 38680555 | ACS Cent Sci | 2024 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/38680555 |
Toward the Next Frontiers of Vibrational Bioimaging. | Wang H, Lee D, Wei L | Chemical & biomedical imaging | 37122829 | Chem Biomed Imaging | 2023 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/37122829 |
Label-free Super-resolution Imaging Enabled by Vibrational Imaging of Swelled Tissue and Analysis. | Miao K, Lin LE, Qian C, Wei L | Journal of visualized experiments : JoVE | 35661092 | J Vis Exp | 2022 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/35661092 |
Bond-selective fluorescence imaging with single-molecule sensitivity. | Wang H, Lee D, Cao Y, Bi X, Du J, Miao K, Wei L | Nature photonics | 38162388 | Nat Photonics | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38162388 |
Nitrile Vibrational Lifetimes as Probes of Local Electric Fields. | Kocheril PA, Wang H, Lee D, Naji N, Wei L | The journal of physical chemistry letters | 38722706 | J Phys Chem Lett | 2024 May 16 | https://www.ncbi.nlm.nih.gov/pubmed/38722706 |
Room-Temperature Single-Molecule Infrared Imaging and Spectroscopy through Bond-Selective Fluorescence. | Wang H, Kocheril PA, Yang Z, Lee D, Naji N, Du J, Lin LE, Wei L | Angewandte Chemie (International ed. in English) | 39312677 | Angew Chem Int Ed Engl | 2024 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/39312677 |
Toward photoswitchable electronic pre-resonance stimulated Raman probes. | Lee D, Qian C, Wang H, Li L, Miao K, Du J, Shcherbakova DM, Verkhusha VV, Wang LV, Wei L | The Journal of chemical physics | 33832245 | J Chem Phys | 2021 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/33832245 |
Super-resolution label-free volumetric vibrational imaging. | Qian C, Miao K, Lin LE, Chen X, Du J, Wei L | Nature communications | 34131146 | Nat Commun | 2021 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/34131146 |
Reentrant DNA shells tune polyphosphate condensate size. | Chawla R, Tom JKA, Boyd T, Grotjahn DA, Park D, Deniz AA, Racki LR | bioRxiv : the preprint server for biology | 37745474 | bioRxiv | 2023 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/37745474 |
Polyphosphate: The "Dark Matter" of Bacterial Chromatin Structure. | Racki LR, Freddolino L | Molecular microbiology | 39967274 | Mol Microbiol | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39967274 |
Reentrant DNA shells tune polyphosphate condensate size. | Chawla R, Tom JKA, Boyd T, Tu NH, Bai T, Grotjahn DA, Park D, Deniz AA, Racki LR | Nature communications | 39462120 | Nat Commun | 2024 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/39462120 |
Polyphosphate affects cytoplasmic and chromosomal dynamics in nitrogen-starved Pseudomonas aeruginosa. | Magkiriadou S, Stepp WL, Newman DK, Manley S, Racki LR | Proceedings of the National Academy of Sciences of the United States of America | 38564631 | Proc Natl Acad Sci U S A | 2024 Apr 9 | https://www.ncbi.nlm.nih.gov/pubmed/38564631 |
A High-Throughput Colocalization Pipeline for Quantification of Mitochondrial Targeting across Different Protein Types. | Lear SK, Nunez JA, Shipman SL | ACS synthetic biology | 37506292 | ACS Synth Biol | 2023 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/37506292 |
An experimental census of retrons for DNA production and genome editing. | Khan AG, Rojas-Montero M, González-Delgado A, Lopez SC, Fang RF, Shipman SL | bioRxiv : the preprint server for biology | 38328236 | bioRxiv | 2024 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/38328236 |
Simultaneous multi-site editing of individual genomes using retron arrays. | González-Delgado A, Lopez SC, Rojas-Montero M, Fishman CB, Shipman SL | Nature chemical biology | 38982310 | Nat Chem Biol | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/38982310 |
One-step data storage in cellular DNA. | Bhattarai-Kline S, Lear SK, Shipman SL | Nature chemical biology | 33500580 | Nat Chem Biol | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33500580 |
Simultaneous multi-site editing of individual genomes using retron arrays. | González-Delgado A, Lopez SC, Rojas-Montero M, Fishman CB, Shipman SL | bioRxiv : the preprint server for biology | 37503029 | bioRxiv | 2023 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/37503029 |
Retron reverse transcriptase termination and phage defense are dependent on host RNase H1. | Palka C, Fishman CB, Bhattarai-Kline S, Myers SA, Shipman SL | Nucleic acids research | 35293583 | Nucleic Acids Res | 2022 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/35293583 |
Molecular recording: transcriptional data collection into the genome. | Lear SK, Shipman SL | Current opinion in biotechnology | 36481341 | Curr Opin Biotechnol | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36481341 |
Continuous Multiplexed Phage Genome Editing Using Recombitrons. | Fishman CB, Crawford KD, Bhattarai-Kline S, Zhang K, González-Delgado A, Shipman SL | bioRxiv : the preprint server for biology | 36993281 | bioRxiv | 2023 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/36993281 |
High-throughput colocalization pipeline quantifies efficacy of mitochondrial targeting signals across different protein types. | Lear SK, Nunez JA, Shipman SL | bioRxiv : the preprint server for biology | 37066162 | bioRxiv | 2023 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/37066162 |
An experimental census of retrons for DNA production and genome editing. | Khan AG, Rojas-Montero M, González-Delgado A, Lopez SC, Fang RF, Crawford KD, Shipman SL | Nature biotechnology | 39289529 | Nat Biotechnol | 2024 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/39289529 |
Continuous multiplexed phage genome editing using recombitrons. | Fishman CB, Crawford KD, Bhattarai-Kline S, Poola D, Zhang K, González-Delgado A, Rojas-Montero M, Shipman SL | Nature biotechnology | 39237706 | Nat Biotechnol | 2024 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/39237706 |
Precise genome editing across kingdoms of life using retron-derived DNA. | Lopez SC, Crawford KD, Lear SK, Bhattarai-Kline S, Shipman SL | Nature chemical biology | 34949838 | Nat Chem Biol | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34949838 |
Temporally resolved transcriptional recording in E. coli DNA using a Retro-Cascorder. | Lear SK, Lopez SC, González-Delgado A, Bhattarai-Kline S, Shipman SL | Nature protocols | 37059915 | Nat Protoc | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37059915 |
Recording gene expression order in DNA by CRISPR addition of retron barcodes. | Bhattarai-Kline S, Lear SK, Fishman CB, Lopez SC, Lockshin ER, Schubert MG, Nivala J, Church GM, Shipman SL | Nature | 35896746 | Nature | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35896746 |
Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma. | Kwok HS, Freedy AM, Siegenfeld AP, Morriss JW, Waterbury AL, Kissler SM, Liau BB | Nature chemical biology | 36973442 | Nat Chem Biol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36973442 |
Base editor screens for in situ mutational scanning at scale. | Lue NZ, Liau BB | Molecular cell | 37390819 | Mol Cell | 2023 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/37390819 |
Oxidation of retromer complex controls mitochondrial translation. | Zhang J, Ali MY, Chong HB, Tien PC, Woods J, Noble C, Vornbäumen T, Ordulu Z, Possemato AP, Harry S, Fonticella JM, Fellah L, Harrison D, Ge M, Khandelwal N, Huang Y, Chauvin M, Bischof AT, Hambelton GM, Gohar MF, Zhang S, Choi M, Bouberhan S, Oliva E, Mino-Kenudson M, Pavlova NN, Lawrence M, Gainor JF, Beausoleil SA, Bardeesy N, Mostoslavsky R, Pépin D, Ott CJ, Liau B, Bar-Peled L | Nature | 40140582 | Nature | 2025 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/40140582 |
CRISPR tiling screen reveals cancer epigenetic 'Goldilocks' state. | Barka A, Kohli RM, Shi J | Trends in pharmacological sciences | 37328396 | Trends Pharmacol Sci | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37328396 |
Base Editor Scanning Reveals Activating Mutations of DNMT3A. | Garcia EM, Lue NZ, Liang JK, Lieberman WK, Hwang DD, Woods JC, Liau BB | ACS chemical biology | 37603861 | ACS Chem Biol | 2023 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/37603861 |
Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance. | Waterbury AL, Caroli J, Zhang O, Tuttle PR, Liu C, Li J, Park JS, Hoenig SM, Barone M, Furui A, Mattevi A, Liau BB | Nature communications | 40175327 | Nat Commun | 2025 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/40175327 |
CRISPR-Suppressor Scanning for Systematic Discovery of Drug-Resistance Mutations. | Ngan KC, Lue NZ, Lee C, Liau BB | Current protocols | 36541895 | Curr Protoc | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36541895 |
Chromatin complex dependencies reveal targeting opportunities in leukemia. | Najm FJ, DeWeirdt P, Moore MM, Bevill SM, El Farran CA, Macias KA, Hegde M, Waterbury AL, Liau BB, van Galen P, Doench JG, Bernstein BE | Nature communications | 36707513 | Nat Commun | 2023 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/36707513 |
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. | Xie X, Zhang O, Yeo MJR, Lee C, Harry SA, Paul L, Li Y, Payne NC, Nam E, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB | bioRxiv : the preprint server for biology | 38798357 | bioRxiv | 2024 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/38798357 |
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway. | Zhang J, Simpson CM, Berner J, Chong HB, Fang J, Ordulu Z, Weiss-Sadan T, Possemato AP, Harry S, Takahashi M, Yang TY, Richter M, Patel H, Smith AE, Carlin AD, Hubertus de Groot AF, Wolf K, Shi L, Wei TY, Dürr BR, Chen NJ, Vornbäumen T, Wichmann NO, Mahamdeh MS, Pooladanda V, Matoba Y, Kumar S, Kim E, Bouberhan S, Oliva E, Rueda BR, Soberman RJ, Bardeesy N, Liau BB, Lawrence M, Stokes MP, Beausoleil SA, Bar-Peled L | Cell | 37192619 | Cell | 2023 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/37192619 |
Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders. | Gosavi PM, Ngan KC, Yeo MJR, Su C, Li J, Lue NZ, Hoenig SM, Liau BB | ACS central science | 35505873 | ACS Cent Sci | 2022 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/35505873 |
Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. | Ngan KC, Hoenig SM, Kwok HS, Lue NZ, Gosavi PM, Tanner DA, Garcia EM, Lee C, Liau BB | eLife | 36762644 | Elife | 2023 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/36762644 |
Discovering new biology with drug-resistance alleles. | Freedy AM, Liau BB | Nature chemical biology | 34799733 | Nat Chem Biol | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34799733 |
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. | Takahashi M, Chong HB, Zhang S, Yang TY, Lazarov MJ, Harry S, Maynard M, Hilbert B, White RD, Murrey HE, Tsou CC, Vordermark K, Assaad J, Gohar M, Dürr BR, Richter M, Patel H, Kryukov G, Brooijmans N, Alghali ASO, Rubio K, Villanueva A, Zhang J, Ge M, Makram F, Griesshaber H, Harrison D, Koglin AS, Ojeda S, Karakyriakou B, Healy A, Popoola G, Rachmin I, Khandelwal N, Neil JR, Tien PC, Chen N, Hosp T, van den Ouweland S, Hara T, Bussema L, Dong R, Shi L, Rasmussen MQ, Domingues AC, Lawless A, Fang J, Yoda S, Nguyen LP, Reeves SM, Wakefield FN, Acker A, Clark SE, Dubash T, Kastanos J, Oh E, Fisher DE, Maheswaran S, Haber DA, Boland GM, Sade-Feldman M, Jenkins RW, Hata AN, Bardeesy NM, Suvà ML, Martin BR, Liau BB, Ott CJ, Rivera MN, Lawrence MS, Bar-Peled L | Cell | 38653237 | Cell | 2024 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/38653237 |
UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors. | Yeo MJR, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Nguyen K, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Carr SA, Udeshi ND, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N | Nature | 39939761 | Nature | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39939761 |
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations. | Xie X, Zhang O, Yeo MJR, Lee C, Tao R, Harry SA, Payne NC, Nam E, Paul L, Li Y, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB | Nature | 39939763 | Nature | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39939763 |
Base editor scanning charts the DNMT3A activity landscape. | Lue NZ, Garcia EM, Ngan KC, Lee C, Doench JG, Liau BB | Nature chemical biology | 36266353 | Nat Chem Biol | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36266353 |
Asymmetric Engagement of Dimeric CRL3 (KBTBD4) by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes. | Yeo MJ, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N | bioRxiv : the preprint server for biology | 38798619 | bioRxiv | 2024 May 14 | https://www.ncbi.nlm.nih.gov/pubmed/38798619 |
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. | Lee K, Barone M, Waterbury AL, Jiang H, Nam E, DuBois-Coyne SE, Whedon SD, Wang ZA, Caroli J, Neal K, Ibeabuchi B, Dhoondia Z, Kuroda MI, Liau BB, Beck S, Mattevi A, Cole PA | Nature chemical biology | 38965385 | Nat Chem Biol | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38965385 |
Metabolic engineering of Escherichia coli for optimized biosynthesis of nicotinamide mononucleotide, a noncanonical redox cofactor. | Black WB, Aspacio D, Bever D, King E, Zhang L, Li H | Microbial cell factories | 32718347 | Microb Cell Fact | 2020 Jul 27 | https://www.ncbi.nlm.nih.gov/pubmed/32718347 |
Engineering Embden-Meyerhof-Parnas Glycolysis to Generate Noncanonical Reducing Power. | King E, Cui Y, Aspacio D, Nicklen F, Zhang L, Maxel S, Luo R, Siegel JB, Aitchison E, Li H | ACS catalysis | 37622090 | ACS Catal | 2022 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/37622090 |
Engineering a nicotinamide mononucleotide redox cofactor system for biocatalysis. | Black WB, Zhang L, Mak WS, Maxel S, Cui Y, King E, Fong B, Sanchez Martinez A, Siegel JB, Li H | Nature chemical biology | 31768035 | Nat Chem Biol | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31768035 |
A Growth-Based, High-Throughput Selection Platform Enables Remodeling of 4-Hydroxybenzoate Hydroxylase Active Site. | Maxel S, Aspacio D, King E, Zhang L, Acosta AP, Li H | ACS catalysis | 34295569 | ACS Catal | 2020 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/34295569 |
Growth-Based, High-Throughput Selection for NADH Preference in an Oxygen-Dependent Biocatalyst. | Maxel S, Saleh S, King E, Aspacio D, Zhang L, Luo R, Li H | ACS synthetic biology | 34469126 | ACS Synth Biol | 2021 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/34469126 |
Design, construction, and application of noncanonical redox cofactor infrastructures. | Black WB, Perea S, Li H | Current opinion in biotechnology | 37939631 | Curr Opin Biotechnol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37939631 |
Shifting Redox Reaction Equilibria on Demand Using an Orthogonal Redox Cofactor. | Aspacio D, Zhang Y, Cui Y, King E, Black WB, Perea S, Luu E, Siegel JB, Li H | bioRxiv : the preprint server for biology | 37693387 | bioRxiv | 2023 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/37693387 |
Engineering natural and noncanonical nicotinamide cofactor-dependent enzymes: design principles and technology development. | King E, Maxel S, Li H | Current opinion in biotechnology | 32956903 | Curr Opin Biotechnol | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32956903 |
Orthogonal glycolytic pathway enables directed evolution of noncanonical cofactor oxidase. | King E, Maxel S, Zhang Y, Kenney KC, Cui Y, Luu E, Siegel JB, Weiss GA, Luo R, Li H | Nature communications | 36435948 | Nat Commun | 2022 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/36435948 |
In Vivo, High-Throughput Selection of Thermostable Cyclohexanone Monooxygenase (CHMO). | Maxel S, Zhang L, King E, Acosta AP, Luo R, Li H | Catalysts (Basel, Switzerland) | 37637965 | Catalysts | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37637965 |
Leveraging Oxidative Stress to Regulate Redox Balance-Based, In Vivo Growth Selections for Oxygenase Engineering. | Maxel S, King E, Zhang Y, Luo R, Li H | ACS synthetic biology | 32966747 | ACS Synth Biol | 2020 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/32966747 |
Aldehyde Production in Crude Lysate- and Whole Cell-Based Biotransformation Using a Noncanonical Redox Cofactor System. | Richardson KN, Black WB, Li H | ACS catalysis | 34306803 | ACS Catal | 2020 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/34306803 |
Directed evolution of phosphite dehydrogenase to cycle noncanonical redox cofactors via universal growth selection platform. | Zhang L, King E, Black WB, Heckmann CM, Wolder A, Cui Y, Nicklen F, Siegel JB, Luo R, Paul CE, Li H | Nature communications | 36028482 | Nat Commun | 2022 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/36028482 |
NAPS: Integrating pose estimation and tag-based tracking. | Wolf SW, Ruttenberg DM, Knapp DY, Webb AE, Traniello IM, McKenzie-Smith GC, Leheny SA, Shaevitz JW, Kocher SD | Methods in ecology and evolution | 38681746 | Methods Ecol Evol | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38681746 |
Developmental transcriptomes predict adult social behaviors in the socially flexible sweat bee, Lasioglossum baleicum. | Omufwoko KS, Cronin AL, Nguyen TTH, Webb AE, Traniello IM, Kocher SD | bioRxiv : the preprint server for biology | 37645955 | bioRxiv | 2023 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/37645955 |
The Molecular Substrates of Insect Eusociality. | Kocher S, Kingwell C | Annual review of genetics | 39146360 | Annu Rev Genet | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39146360 |
Integrating computer vision and molecular neurobiology to bridge the gap between behavior and the brain. | Traniello IM, Kocher SD | Current opinion in insect science | 39244088 | Curr Opin Insect Sci | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39244088 |
Repeated Shifts in Sociality Are Associated With Fine-tuning of Highly Conserved and Lineage-Specific Enhancers in a Socially Flexible Bee. | Jones BM, Webb AE, Geib SM, Sim S, Schweizer RM, Branstetter MG, Evans JD, Kocher SD | Molecular biology and evolution | 39487572 | Mol Biol Evol | 2024 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/39487572 |
Isolation disrupts social interactions and destabilizes brain development in bumblebees. | Wang ZY, McKenzie-Smith GC, Liu W, Cho HJ, Pereira T, Dhanerawala Z, Shaevitz JW, Kocher SD | Current biology : CB | 35584698 | Curr Biol | 2022 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/35584698 |
Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants. | Ju L, Glastad KM, Sheng L, Gospocic J, Kingwell CJ, Davidson SM, Kocher SD, Bonasio R, Berger SL | Cell | 37683635 | Cell | 2023 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/37683635 |
Variation in season length and development time is sufficient to drive the emergence and coexistence of social and solitary behavioral strategies. | Ruttenberg DM, Levin SA, Wingreen NS, Kocher SD | bioRxiv : the preprint server for biology | 38948882 | bioRxiv | 2024 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/38948882 |
Convergent and complementary selection shaped gains and losses of eusociality in sweat bees. | Jones BM, Rubin BER, Dudchenko O, Kingwell CJ, Traniello IM, Wang ZY, Kapheim KM, Wyman ES, Adastra PA, Liu W, Parsons LR, Jackson SR, Goodwin K, Davidson SM, McBride MJ, Webb AE, Omufwoko KS, Van Dorp N, Otárola MF, Pham M, Omer AD, Weisz D, Schraiber J, Villanea F, Wcislo WT, Paxton RJ, Hunt BG, Aiden EL, Kocher SD | Nature ecology & evolution | 36941345 | Nat Ecol Evol | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36941345 |
Developmental transcriptomes predict adult social behaviours in the socially flexible sweat bee, Lasioglossum baleicum. | Omufwoko KS, Cronin AL, Nguyen TTH, Webb AE, Traniello IM, Kocher SD | Molecular ecology | 38108560 | Mol Ecol | 2023 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/38108560 |
Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing. | Yang R, Feng X, Arias-Cavieres A, Mitchell RM, Polo A, Hu K, Zhong R, Qi C, Zhang RS, Westneat N, Portillo CA, Nobrega MA, Hansel C, Garcia Iii AJ, Zhang X | Neuron | 36917980 | Neuron | 2023 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/36917980 |
Variants in ADD1 cause intellectual disability, corpus callosum dysgenesis, and ventriculomegaly in humans. | Qi C, Feng I, Costa AR, Pinto-Costa R, Neil JE, Caluseriu O, Li D, Ganetzky RD, Brasch-Andersen C, Fagerberg C, Hansen LK, Bupp C, Muraresku CC, Ruan X, Kang B, Hu K, Zhong R, Brites P, Bhoj EJ, Hill RS, Falk MJ, Hakonarson H, Kahle KT, Sousa MM, Walsh CA, Zhang X | Genetics in medicine : official journal of the American College of Medical Genetics | 34906466 | Genet Med | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34906466 |
Progenitor cell diversity in the developing mouse neocortex. | Ruan X, Kang B, Qi C, Lin W, Wang J, Zhang X | Proceedings of the National Academy of Sciences of the United States of America | 33649223 | Proc Natl Acad Sci U S A | 2021 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/33649223 |
PIE-seq: identifying RNA-binding protein targets by dual RNA-deaminase editing and sequencing. | Ruan X, Hu K, Zhang X | Nature communications | 37280234 | Nat Commun | 2023 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/37280234 |
Infernape uncovers cell type-specific and spatially resolved alternative polyadenylation in the brain. | Kang B, Yang Y, Hu K, Ruan X, Liu YL, Lee P, Lee J, Wang J, Zhang X | Genome research | 37907328 | Genome Res | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37907328 |
Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons. | Yang Y, Yang R, Kang B, Qian S, He X, Zhang X | Cell reports | 37889749 | Cell Rep | 2023 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/37889749 |
Splice-switching antisense oligonucleotides for pediatric neurological disorders. | Zhang X | Frontiers in molecular neuroscience | 39119251 | Front Mol Neurosci | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/39119251 |
Cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex. | Ruan X, Hu K, Yang Y, Yang R, Tseng E, Kang B, Kauffman A, Zhong R, Zhang X | bioRxiv : the preprint server for biology | 39314274 | bioRxiv | 2024 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/39314274 |
Standardized annotation of translated open reading frames. | Mudge JM, Ruiz-Orera J, Prensner JR, Brunet MA, Calvet F, Jungreis I, Gonzalez JM, Magrane M, Martinez TF, Schulz JF, Yang YT, Albà MM, Aspden JL, Baranov PV, Bazzini AA, Bruford E, Martin MJ, Calviello L, Carvunis AR, Chen J, Couso JP, Deutsch EW, Flicek P, Frankish A, Gerstein M, Hubner N, Ingolia NT, Kellis M, Menschaert G, Moritz RL, Ohler U, Roucou X, Saghatelian A, Weissman JS, van Heesch S | Nature biotechnology | 35831657 | Nat Biotechnol | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35831657 |
Integrative detection of genome-wide translation using iRibo. | Turcan A, Lee J, Wacholder A, Carvunis AR | STAR protocols | 38217852 | STAR Protoc | 2024 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/38217852 |
Cellular processing of beneficial de novo emerging proteins. | Houghton CJ, Coelho NC, Chiang A, Hedayati S, Parikh SB, Ozbaki-Yagan N, Wacholder A, Iannotta J, Berger A, Carvunis AR, O'Donnell AF | bioRxiv : the preprint server for biology | 39257767 | bioRxiv | 2024 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/39257767 |
A vast evolutionarily transient translatome contributes to phenotype and fitness. | Wacholder A, Parikh SB, Coelho NC, Acar O, Houghton C, Chou L, Carvunis AR | Cell systems | 37164009 | Cell Syst | 2023 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/37164009 |
Ancestral Sequence Reconstruction as a Tool to Detect and Study De Novo Gene Emergence. | Vakirlis N, Acar O, Cherupally V, Carvunis AR | Genome biology and evolution | 39004885 | Genome Biol Evol | 2024 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/39004885 |
LI Detector: a framework for sensitive colony-based screens regardless of the distribution of fitness effects. | Parikh SB, Castilho Coelho N, Carvunis AR | G3 (Bethesda, Md.) | 33693606 | G3 (Bethesda) | 2021 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/33693606 |
De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences. | Vakirlis N, Acar O, Hsu B, Castilho Coelho N, Van Oss SB, Wacholder A, Medetgul-Ernar K, Bowman RW 2nd, Hines CP, Iannotta J, Parikh SB, McLysaght A, Camacho CJ, O'Donnell AF, Ideker T, Carvunis AR | Nature communications | 32034123 | Nat Commun | 2020 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/32034123 |
Biological factors and statistical limitations prevent detection of most noncanonical proteins by mass spectrometry. | Wacholder A, Carvunis AR | PLoS biology | 38048358 | PLoS Biol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/38048358 |
A Legionella effector ADP-ribosyltransferase inactivates glutamate dehydrogenase. | Black MH, Osinski A, Park GJ, Gradowski M, Servage KA, Pawłowski K, Tagliabracci VS | The Journal of biological chemistry | 33476647 | J Biol Chem | 2021 Jan-Jun | https://www.ncbi.nlm.nih.gov/pubmed/33476647 |
Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation. | Hu Y, Lopez VA, Xu H, Pfister JP, Song B, Servage KA, Sakurai M, Jones BT, Mendell JT, Wang T, Wu J, Lambowitz AM, Tomchick DR, Pawłowski K, Tagliabracci VS | bioRxiv : the preprint server for biology | 38712170 | bioRxiv | 2024 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/38712170 |
Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation. | Hu Y, Lopez VA, Xu H, Pfister JP, Song B, Servage KA, Sakurai M, Jones BT, Mendell JT, Wang T, Wu J, Lambowitz AM, Tomchick DR, Pawłowski K, Tagliabracci VS | Proceedings of the National Academy of Sciences of the United States of America | 39388274 | Proc Natl Acad Sci U S A | 2024 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/39388274 |
Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases. | Black MH, Osinski A, Gradowski M, Servage KA, Pawłowski K, Tomchick DR, Tagliabracci VS | Science (New York, N.Y.) | 31123136 | Science | 2019 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/31123136 |
Structural and mechanistic basis for protein glutamylation by the kinase fold. | Osinski A, Black MH, Pawłowski K, Chen Z, Li Y, Tagliabracci VS | Molecular cell | 34407442 | Mol Cell | 2021 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/34407442 |
A Legionella effector kinase is activated by host inositol hexakisphosphate. | Sreelatha A, Nolan C, Park BC, Pawłowski K, Tomchick DR, Tagliabracci VS | The Journal of biological chemistry | 32229585 | J Biol Chem | 2020 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/32229585 |
Methods for discovering catalytic activities for pseudokinases. | Black MH, Gradowski M, Pawłowski K, Tagliabracci VS | Methods in enzymology | 35525554 | Methods Enzymol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35525554 |
Dynamic remodeling of host membranes by self-organizing bacterial effectors. | Hsieh TS, Lopez VA, Black MH, Osinski A, Pawłowski K, Tomchick DR, Liou J, Tagliabracci VS | Science (New York, N.Y.) | 33927055 | Science | 2021 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/33927055 |
The mechanism of RNA capping by SARS-CoV-2. | Park GJ, Osinski A, Hernandez G, Eitson JL, Majumdar A, Tonelli M, Henzler-Wildman K, Pawłowski K, Chen Z, Li Y, Schoggins JW, Tagliabracci VS | Research square | 35194601 | Res Sq | 2022 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/35194601 |
Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens. | Karvas RM, Khan SA, Verma S, Yin Y, Kulkarni D, Dong C, Park KM, Chew B, Sane E, Fischer LA, Kumar D, Ma L, Boon ACM, Dietmann S, Mysorekar IU, Theunissen TW | Cell stem cell | 35523141 | Cell Stem Cell | 2022 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/35523141 |
SARS-CoV-2 ORF3a Protein Impairs Syncytiotrophoblast Maturation, Alters ZO-1 Localization, and Shifts Autophagic Pathways in Trophoblast Cells and 3D Organoids. | Kumar D, Karvas RM, Jones BR, McColl ER, Diveley E, Sukanta J, Surendra S, Kelly JC, Theunissen TW, Mysorekar IU | bioRxiv : the preprint server for biology | 39386577 | bioRxiv | 2024 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/39386577 |
Tracking and mitigating imprint erasure during induction of naive human pluripotency at single-cell resolution. | Fischer LA, Meyer B, Reyes M, Zemke JE, Harrison JK, Park KM, Wang T, Jüppner H, Dietmann S, Theunissen TW | Stem cell reports | 39952244 | Stem Cell Reports | 2025 Mar 11 | https://www.ncbi.nlm.nih.gov/pubmed/39952244 |
Recent insights into the naïve state of human pluripotency and its applications. | Dong C, Fischer LA, Theunissen TW | Experimental cell research | 31585117 | Exp Cell Res | 2019 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/31585117 |
Biomaterials to enhance stem cell transplantation. | Kharbikar BN, Mohindra P, Desai TA | Cell stem cell | 35483364 | Cell Stem Cell | 2022 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/35483364 |
Induction of Human Naïve Pluripotency Using 5i/L/A Medium. | Fischer LA, Khan SA, Theunissen TW | Methods in molecular biology (Clifton, N.J.) | 34870827 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/34870827 |
Generating Trophoblast Stem Cells from Human Naïve Pluripotent Stem Cells. | Dong C, Theunissen TW | Methods in molecular biology (Clifton, N.J.) | 34870832 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/34870832 |
Accessing the human trophoblast stem cell state from pluripotent and somatic cells. | Karvas RM, David L, Theunissen TW | Cellular and molecular life sciences : CMLS | 36434136 | Cell Mol Life Sci | 2022 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/36434136 |
Derivation of trophoblast stem cells from naïve human pluripotent stem cells. | Dong C, Beltcheva M, Gontarz P, Zhang B, Popli P, Fischer LA, Khan SA, Park KM, Yoon EJ, Xing X, Kommagani R, Wang T, Solnica-Krezel L, Theunissen TW | eLife | 32048992 | Elife | 2020 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/32048992 |
Modeling X-chromosome inactivation and reactivation during human development. | Khan SA, Theunissen TW | Current opinion in genetics & development | 37597506 | Curr Opin Genet Dev | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37597506 |
OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human. | Huang X, Park KM, Gontarz P, Zhang B, Pan J, McKenzie Z, Fischer LA, Dong C, Dietmann S, Xing X, Shliaha PV, Yang J, Li D, Ding J, Lungjangwa T, Mitalipova M, Khan SA, Imsoonthornruksa S, Jensen N, Wang T, Kadoch C, Jaenisch R, Wang J, Theunissen TW | Nature communications | 34446700 | Nat Commun | 2021 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/34446700 |
A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. | Dong C, Fu S, Karvas RM, Chew B, Fischer LA, Xing X, Harrison JK, Popli P, Kommagani R, Wang T, Zhang B, Theunissen TW | Nature communications | 35538076 | Nat Commun | 2022 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/35538076 |
Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening. | Khan SA, Park KM, Fischer LA, Dong C, Lungjangwa T, Jimenez M, Casalena D, Chew B, Dietmann S, Auld DS, Jaenisch R, Theunissen TW | Cell reports | 34133938 | Cell Rep | 2021 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/34133938 |
iPSC-based modeling of preeclampsia identifies epigenetic defects in extravillous trophoblast differentiation. | Morey R, Bui T, Cheung VC, Dong C, Zemke JE, Requena D, Arora H, Jackson MG, Pizzo D, Theunissen TW, Horii M | iScience | 38623329 | iScience | 2024 Apr 19 | https://www.ncbi.nlm.nih.gov/pubmed/38623329 |
Generation of 3D Trophoblast Organoids from Human Naïve Pluripotent Stem Cells. | Karvas RM, Theunissen TW | Methods in molecular biology (Clifton, N.J.) | 37402094 | Methods Mol Biol | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/37402094 |
Modular control of l-tryptophan isotopic substitution via an efficient biosynthetic cascade. | Thompson CM, McDonald AD, Yang H, Cavagnero S, Buller AR | Organic & biomolecular chemistry | 32452506 | Org Biomol Chem | 2020 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/32452506 |
Site-Selective Deuteration of Amino Acids through Dual-Protein Catalysis. | Doyon TJ, Buller AR | Journal of the American Chemical Society | 35416652 | J Am Chem Soc | 2022 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/35416652 |
Biocatalytic synthesis of non-standard amino acids by a decarboxylative aldol reaction. | Ellis JM, Campbell ME, Kumar P, Geunes EP, Bingman CA, Buller AR | Nature catalysis | 35935533 | Nat Catal | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35935533 |
Multiplexed Assessment of Promiscuous Non-Canonical Amino Acid Synthase Activity in a Pyridoxal Phosphate-Dependent Protein Family. | Zmich A, Perkins LJ, Bingman C, Acheson JF, Buller AR | ACS catalysis | 37720819 | ACS Catal | 2023 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/37720819 |
Occupational modulation in the (3+1)-dimensional incommensurate structure of (2S,3S)-2-amino-3-hydroxy-3-methyl-4-phenoxybutanoic acid dihydrate. | Sanders KM, Bruffy SK, Buller AR, Petříček V, Guzei IA | Acta crystallographica. Section C, Structural chemistry | 39115533 | Acta Crystallogr C Struct Chem | 2024 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/39115533 |
Substrate-Multiplexed Assessment of Aromatic Prenyltransferase Activity. | Higgins PM, Wehrli NG, Buller AR | Chembiochem : a European journal of chemical biology | 39317170 | Chembiochem | 2025 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/39317170 |
l-Threonine Transaldolase Activity Is Enabled by a Persistent Catalytic Intermediate. | Kumar P, Meza A, Ellis JM, Carlson GA, Bingman CA, Buller AR | ACS chemical biology | 33337128 | ACS Chem Biol | 2021 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/33337128 |
Engineered Biocatalytic Synthesis of β-N-Substituted-α-Amino Acids. | Villalona J, Higgins PM, Buller AR | Angewandte Chemie (International ed. in English) | 37625129 | Angew Chem Int Ed Engl | 2023 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/37625129 |
Scalable and Selective β-Hydroxy-α-Amino Acid Synthesis Catalyzed by Promiscuous l-Threonine Transaldolase ObiH. | Doyon TJ, Kumar P, Thein S, Kim M, Stitgen A, Grieger AM, Madigan C, Willoughby PH, Buller AR | Chembiochem : a European journal of chemical biology | 34699683 | Chembiochem | 2022 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/34699683 |
Asymmetric Alkylation of Ketones Catalyzed by Engineered TrpB. | Watkins-Dulaney EJ, Dunham NP, Straathof S, Turi S, Arnold FH, Buller AR | Angewandte Chemie (International ed. in English) | 34269506 | Angew Chem Int Ed Engl | 2021 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/34269506 |
Efficient chemoenzymatic synthesis of α-aryl aldehydes as intermediates in C-C bond forming biocatalytic cascades. | Meza A, Campbell ME, Zmich A, Thein SA, Grieger AM, McGill MJ, Willoughby PH, Buller AR | ACS catalysis | 36420479 | ACS Catal | 2022 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/36420479 |
Elucidation of the stereochemical mechanism of cystathionine γ-lyase reveals how substrate specificity constrains catalysis. | Zmich A, Perkins LJ, Bingman C, Buller AR | ACS catalysis | 39391268 | ACS Catal | 2024 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/39391268 |
Biocatalytic asymmetric aldol addition into unactivated ketones. | Bruffy SK, Meza A, Soler J, Doyon TJ, Young SH, Lim J, Huseth KG, Willoughby PH, Garcia-Borràs M, Buller AR | Nature chemistry | 39333392 | Nat Chem | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39333392 |
Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis. | McDonald AD, Higgins PM, Buller AR | Nature communications | 36068220 | Nat Commun | 2022 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/36068220 |
Investigation of β-Substitution Activity of O-Acetylserine Sulfhydrolase from Citrullus vulgaris. | Smith JL, Harrison IM, Bingman CA, Buller AR | Chembiochem : a European journal of chemical biology | 35476889 | Chembiochem | 2022 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/35476889 |
Engineering Enzyme Substrate Scope Complementarity for Promiscuous Cascade Synthesis of 1,2-Amino Alcohols. | McDonald AD, Bruffy SK, Kasat AT, Buller AR | Angewandte Chemie (International ed. in English) | 36136093 | Angew Chem Int Ed Engl | 2022 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/36136093 |
Efficient and flexible tagging of endogenous genes by homology-independent intron targeting. | Serebrenik YV, Sansbury SE, Kumar SS, Henao-Mejia J, Shalem O | Genome research | 31239279 | Genome Res | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31239279 |
CRISPR associated enzymes are mislocalized to the cytoplasm in iPSC-derived neurons resulting in KRAB-specific degradation. | Cajka G, Liu M, Shalem O | bioRxiv : the preprint server for biology | 39464063 | bioRxiv | 2024 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/39464063 |
Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics. | Serebrenik YV, Mani D, Maujean T, Burslem GM, Shalem O | Research square | 37790450 | Res Sq | 2023 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/37790450 |
CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. | Sweeney KM, Chantarawong S, Barbieri EM, Cajka G, Liu M, Spruce L, Fazelinia H, Portz B, Copley K, Lapidot T, Duhamel L, Greenwald P, Saida N, Shalgi R, Shorter J, Shalem O | PLoS genetics | 38315730 | PLoS Genet | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38315730 |
Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses. | Sansbury SE, Serebrenik YV, Lapidot T, Burslem GM, Shalem O | bioRxiv : the preprint server for biology | 37503003 | bioRxiv | 2023 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/37503003 |
Pooled endogenous protein tagging and recruitment for systematic profiling of protein function. | Serebrenik YV, Mani D, Maujean T, Burslem GM, Shalem O | Cell genomics | 39255790 | Cell Genom | 2024 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/39255790 |
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins. | Viera Ortiz AP, Cajka G, Olatunji OA, Mikytuck B, Shalem O, Lee EB | Brain : a journal of neurology | 36516294 | Brain | 2023 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/36516294 |
Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin function and life span. | Garcia G, Bar-Ziv R, Averbukh M, Dasgupta N, Dutta N, Zhang H, Fan W, Moaddeli D, Tsui CK, Castro Torres T, Alcala A, Moehle EA, Hoang S, Shalem O, Adams PD, Thorwald MA, Higuchi-Sanabria R | Aging cell | 36404134 | Aging Cell | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36404134 |
High-throughput optimized prime editing mediated endogenous protein tagging for pooled imaging of protein localization. | Sanchez HM, Lapidot T, Shalem O | bioRxiv : the preprint server for biology | 39345511 | bioRxiv | 2024 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/39345511 |
Intracellular Protein Editing to Enable Incorporation of Non-Canonical Residues into Endogenous Proteins. | Beyer JN, Serebrenik YV, Toy K, Najar MA, Raniszewski NR, Shalem O, Burslem GM | bioRxiv : the preprint server for biology | 39026884 | bioRxiv | 2024 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/39026884 |
CRISPR screen for rAAV production implicates genes associated with infection. | O'Driscoll EE, Arora S, Lang JF, Davidson BL, Shalem O | bioRxiv : the preprint server for biology | 39345423 | bioRxiv | 2024 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/39345423 |
ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins. | McKenna MJ, Adams BM, Chu V, Paulo JA, Shao S | Molecular cell | 36283413 | Mol Cell | 2022 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/36283413 |
Detecting and Rescuing Stalled Ribosomes. | Yip MCJ, Shao S | Trends in biochemical sciences | 33966939 | Trends Biochem Sci | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/33966939 |
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase. | McKenna MJ, Sim SI, Ordureau A, Wei L, Harper JW, Shao S, Park E | Science (New York, N.Y.) | 32973005 | Science | 2020 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/32973005 |
Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. | Koga Y, Hoang EM, Park Y, Keszei AFA, Murray J, Shao S, Liau BB | Journal of the American Chemical Society | 34403584 | J Am Chem Soc | 2021 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/34403584 |
Mechanism of ASF1 Inhibition by CDAN1. | Sedor SF, Shao S | bioRxiv : the preprint server for biology | 39149339 | bioRxiv | 2024 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/39149339 |
Mechanism of ASF1 engagement by CDAN1. | Sedor SF, Shao S | Nature communications | 40091041 | Nat Commun | 2025 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/40091041 |
ELAC1 Repairs tRNAs Cleaved during Ribosome-Associated Quality Control. | Yip MCJ, Savickas S, Gygi SP, Shao S | Cell reports | 32075755 | Cell Rep | 2020 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/32075755 |
Selective destabilization of polypeptides synthesized from NMD-targeted transcripts. | Chu V, Feng Q, Lim Y, Shao S | Molecular biology of the cell | 34586879 | Mol Biol Cell | 2021 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/34586879 |
Mechanism of client selection by the protein quality-control factor UBE2O. | Yip MCJ, Sedor SF, Shao S | Nature structural & molecular biology | 35915257 | Nat Struct Mol Biol | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35915257 |
The Endoplasmic Reticulum and the Fidelity of Nascent Protein Localization. | McKenna MJ, Shao S | Cold Spring Harbor perspectives in biology | 36041782 | Cold Spring Harb Perspect Biol | 2023 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/36041782 |
Structural insights into metazoan pretargeting GET complexes. | Keszei AFA, Yip MCJ, Hsieh TC, Shao S | Nature structural & molecular biology | 34887561 | Nat Struct Mol Biol | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34887561 |
The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center. | Coelho JPL, Yip MCJ, Oltion K, Taunton J, Shao S | Nature chemical biology | 38172604 | Nat Chem Biol | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38172604 |
Cotranslational molecular condensation of cochaperones and assembly factors facilitates axonemal dynein biogenesis. | Li Y, Xu W, Cheng Y, Djenoune L, Zhuang C, Cox AL, Britto CJ, Yuan S, Wang S, Sun Z | Proceedings of the National Academy of Sciences of the United States of America | 39541357 | Proc Natl Acad Sci U S A | 2024 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/39541357 |
Multiplexed imaging of nucleome architectures in single cells of mammalian tissue. | Liu M, Lu Y, Yang B, Chen Y, Radda JSD, Hu M, Katz SG, Wang S | Nature communications | 32518300 | Nat Commun | 2020 Jun 9 | https://www.ncbi.nlm.nih.gov/pubmed/32518300 |
TAD-like single-cell domain structures exist on both active and inactive X chromosomes and persist under epigenetic perturbations. | Cheng Y, Liu M, Hu M, Wang S | Genome biology | 34749781 | Genome Biol | 2021 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/34749781 |
Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery. | Liu M, Jin S, Agabiti SS, Jensen TB, Yang T, Radda JSD, Ruiz CF, Baldissera G, Rajaei M, Townsend JP, Muzumdar MD, Wang S | bioRxiv : the preprint server for biology | 37546882 | bioRxiv | 2024 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/37546882 |
Regulation of gene editing using T-DNA concatenation. | Dickinson L, Yuan W, LeBlanc C, Thomson G, Wang S, Jacob Y | Nature plants | 37653336 | Nat Plants | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37653336 |
Chromatin tracing and multiplexed imaging of nucleome architectures (MINA) and RNAs in single mammalian cells and tissue. | Liu M, Yang B, Hu M, Radda JSD, Chen Y, Jin S, Cheng Y, Wang S | Nature protocols | 33903756 | Nat Protoc | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33903756 |
Lamina-Dependent Stretching and Unconventional Chromosome Compartments in Early C. elegans Embryos. | Sawh AN, Shafer MER, Su JH, Zhuang X, Wang S, Mango SE | Molecular cell | 32105612 | Mol Cell | 2020 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/32105612 |
Sequencing-free whole genome spatial transcriptomics at molecular resolution in intact tissue. | Cheng Y, Dang S, Zhang Y, Chen Y, Yu R, Liu M, Jin S, Han A, Katz S, Wang S | bioRxiv : the preprint server for biology | 40161724 | bioRxiv | 2025 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/40161724 |
G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration. | Boraas LC, Hu M, Martino P, Thornton L, Vejnar CE, Zhen G, Zeng L, Parker DM, Cox AL, Giraldez AJ, Su X, Mayr C, Wang S, Nicoli S | Cell reports | 39883578 | Cell Rep | 2025 Feb 25 | https://www.ncbi.nlm.nih.gov/pubmed/39883578 |
New mechanism of chromatin compartmentalization by BRD2. | Cheng Y, Wang S | Trends in genetics : TIG | 35811175 | Trends Genet | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/35811175 |
Perturb-tracing enables high-content screening of multiscale 3D genome regulators. | Cheng Y, Hu M, Yang B, Jensen TB, Yang T, Yu R, Ma Z, Radda JSD, Jin S, Zang C, Wang S | bioRxiv : the preprint server for biology | 36778402 | bioRxiv | 2023 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/36778402 |
Chromatin Tracing: Imaging 3D Genome and Nucleome. | Hu M, Wang S | Trends in cell biology | 33191055 | Trends Cell Biol | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33191055 |
An integrated platform for high-throughput nanoscopy. | Barentine AES, Lin Y, Courvan EM, Kidd P, Liu M, Balduf L, Phan T, Rivera-Molina F, Grace MR, Marin Z, Lessard M, Rios Chen J, Wang S, Neugebauer KM, Bewersdorf J, Baddeley D | Nature biotechnology | 36914886 | Nat Biotechnol | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/36914886 |
Induction of T-DNA amplification by retrotransposon-derived sequences. | Dickinson L, Yuan W, LeBlanc C, Thomson G, Wang S, Jacob Y | bioRxiv : the preprint server for biology | 36945545 | bioRxiv | 2023 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/36945545 |
Female naïve human pluripotent stem cells carry X chromosomes with Xa-like and Xi-like folding conformations. | Patterson B, Yang B, Tanaka Y, Kim KY, Cakir B, Xiang Y, Kim J, Wang S, Park IH | Science advances | 37540754 | Sci Adv | 2023 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/37540754 |
Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome. | Wang SE, Cheng Y, Lim J, Jang MA, Forrest EN, Kim Y, Donahue M, Qiao SN, Xiong Y, Jin J, Wang S, Jiang YH | Research square | 39011107 | Res Sq | 2024 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/39011107 |
TransDiscovery: Discovering Biotransformation from Human Microbiota by Integrating Metagenomic and Metabolomic Data. | Yan D, Cao L, Zhou M, Mohimani H | Metabolites | 35208194 | Metabolites | 2022 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/35208194 |
Bacillus subtilis biofilm matrix components target seed oil bodies to promote growth and anti-fungal resistance in melon. | Berlanga-Clavero MV, Molina-Santiago C, Caraballo-Rodríguez AM, Petras D, Díaz-Martínez L, Pérez-García A, de Vicente A, Carrión VJ, Dorrestein PC, Romero D | Nature microbiology | 35668112 | Nat Microbiol | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35668112 |
Feature-based molecular networking in the GNPS analysis environment. | Nothias LF, Petras D, Schmid R, Dührkop K, Rainer J, Sarvepalli A, Protsyuk I, Ernst M, Tsugawa H, Fleischauer M, Aicheler F, Aksenov AA, Alka O, Allard PM, Barsch A, Cachet X, Caraballo-Rodriguez AM, Da Silva RR, Dang T, Garg N, Gauglitz JM, Gurevich A, Isaac G, Jarmusch AK, Kameník Z, Kang KB, Kessler N, Koester I, Korf A, Le Gouellec A, Ludwig M, Martin H C, McCall LI, McSayles J, Meyer SW, Mohimani H, Morsy M, Moyne O, Neumann S, Neuweger H, Nguyen NH, Nothias-Esposito M, Paolini J, Phelan VV, Pluskal T, Quinn RA, Rogers S, Shrestha B, Tripathi A, van der Hooft JJJ, Vargas F, Weldon KC, Witting M, Yang H, Zhang Z, Zubeil F, Kohlbacher O, Böcker S, Alexandrov T, Bandeira N, Wang M, Dorrestein PC | Nature methods | 32839597 | Nat Methods | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32839597 |
An interpretable machine learning approach to identify mechanism of action of antibiotics. | Mongia M, Guler M, Mohimani H | Scientific reports | 35725893 | Sci Rep | 2022 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/35725893 |
MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities. | Cao L, Gurevich A, Alexander KL, Naman CB, Leão T, Glukhov E, Luzzatto-Knaan T, Vargas F, Quinn R, Bouslimani A, Nothias LF, Singh NK, Sanders JG, Benitez RAS, Thompson LR, Hamid MN, Morton JT, Mikheenko A, Shlemov A, Korobeynikov A, Friedberg I, Knight R, Venkateswaran K, Gerwick WH, Gerwick L, Dorrestein PC, Pevzner PA, Mohimani H | Cell systems | 31629686 | Cell Syst | 2019 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/31629686 |
Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery. | Behsaz B, Bode E, Gurevich A, Shi YN, Grundmann F, Acharya D, Caraballo-Rodríguez AM, Bouslimani A, Panitchpakdi M, Linck A, Guan C, Oh J, Dorrestein PC, Bode HB, Pevzner PA, Mohimani H | Nature communications | 34050176 | Nat Commun | 2021 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/34050176 |
Chemical Gradients of Plant Substrates in an Atta texana Fungus Garden. | Caraballo-Rodríguez AM, Puckett SP, Kyle KE, Petras D, da Silva R, Nothias LF, Ernst M, van der Hooft JJJ, Tripathi A, Wang M, Balunas MJ, Klassen JL, Dorrestein PC | mSystems | 34342533 | mSystems | 2021 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/34342533 |
Repository scale classification and decomposition of tandem mass spectral data. | Mongia M, Mohimani H | Scientific reports | 33859284 | Sci Rep | 2021 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/33859284 |
HypoRiPPAtlas as an Atlas of hypothetical natural products for mass spectrometry database search. | Lee YY, Guler M, Chigumba DN, Wang S, Mittal N, Miller C, Krummenacher B, Liu H, Cao L, Kannan A, Narayan K, Slocum ST, Roth BL, Gurevich A, Behsaz B, Kersten RD, Mohimani H | Nature communications | 37452020 | Nat Commun | 2023 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/37452020 |
microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data. | Zuffa S, Schmid R, Bauermeister A, P Gomes PW, Caraballo-Rodriguez AM, El Abiead Y, Aron AT, Gentry EC, Zemlin J, Meehan MJ, Avalon NE, Cichewicz RH, Buzun E, Terrazas MC, Hsu CY, Oles R, Ayala AV, Zhao J, Chu H, Kuijpers MCM, Jackrel SL, Tugizimana F, Nephali LP, Dubery IA, Madala NE, Moreira EA, Costa-Lotufo LV, Lopes NP, Rezende-Teixeira P, Jimenez PC, Rimal B, Patterson AD, Traxler MF, Pessotti RC, Alvarado-Villalobos D, Tamayo-Castillo G, Chaverri P, Escudero-Leyva E, Quiros-Guerrero LM, Bory AJ, Joubert J, Rutz A, Wolfender JL, Allard PM, Sichert A, Pontrelli S, Pullman BS, Bandeira N, Gerwick WH, Gindro K, Massana-Codina J, Wagner BC, Forchhammer K, Petras D, Aiosa N, Garg N, Liebeke M, Bourceau P, Kang KB, Gadhavi H, de Carvalho LPS, Silva Dos Santos M, Pérez-Lorente AI, Molina-Santiago C, Romero D, Franke R, Brönstrup M, Vera Ponce de León A, Pope PB, La Rosa SL, La Barbera G, Roager HM, Laursen MF, Hammerle F, Siewert B, Peintner U, Licona-Cassani C, Rodriguez-Orduña L, Rampler E, Hildebrand F, Koellensperger G, Schoeny H, Hohenwallner K, Panzenboeck L, Gregor R, O'Neill EC, Roxborough ET, Odoi J, Bale NJ, Ding S, Sinninghe Damsté JS, Guan XL, Cui JJ, Ju KS, Silva DB, Silva FMR, da Silva GF, Koolen HHF, Grundmann C, Clement JA, Mohimani H, Broders K, McPhail KL, Ober-Singleton SE, Rath CM, McDonald D, Knight R, Wang M, Dorrestein PC | Nature microbiology | 38316926 | Nat Microbiol | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38316926 |
Discovering type I cis-AT polyketides through computational mass spectrometry and genome mining with Seq2PKS. | Yan D, Zhou M, Adduri A, Zhuang Y, Guler M, Liu S, Shin H, Kovach T, Oh G, Liu X, Deng Y, Wang X, Cao L, Sherman DH, Schultz PJ, Kersten RD, Clement JA, Tripathi A, Behsaz B, Mohimani H | Nature communications | 38918378 | Nat Commun | 2024 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/38918378 |
A Metabolome- and Metagenome-Wide Association Network Reveals Microbial Natural Products and Microbial Biotransformation Products from the Human Microbiota. | Cao L, Shcherbin E, Mohimani H | mSystems | 31455639 | mSystems | 2019 Aug 27 | https://www.ncbi.nlm.nih.gov/pubmed/31455639 |
De Novo Peptide Sequencing Reveals Many Cyclopeptides in the Human Gut and Other Environments. | Behsaz B, Mohimani H, Gurevich A, Prjibelski A, Fisher M, Vargas F, Smarr L, Dorrestein PC, Mylne JS, Pevzner PA | Cell systems | 31864964 | Cell Syst | 2020 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/31864964 |
Chemical interplay and complementary adaptative strategies toggle bacterial antagonism and co-existence. | Molina-Santiago C, Vela-Corcía D, Petras D, Díaz-Martínez L, Pérez-Lorente AI, Sopeña-Torres S, Pearson J, Caraballo-Rodríguez AM, Dorrestein PC, de Vicente A, Romero D | Cell reports | 34320359 | Cell Rep | 2021 Jul 27 | https://www.ncbi.nlm.nih.gov/pubmed/34320359 |
A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data. | Zuffa S, Schmid R, Bauermeister A, Gomes PWP, Caraballo-Rodriguez AM, Abiead YE, Aron AT, Gentry EC, Zemlin J, Meehan MJ, Avalon NE, Cichewicz RH, Buzun E, Terrazas MC, Hsu CY, Oles R, Ayala AV, Zhao J, Chu H, Kuijpers MCM, Jackrel SL, Tugizimana F, Nephali LP, Dubery IA, Madala NE, Moreira EA, Costa-Lotufo LV, Lopes NP, Rezende-Teixeira P, Jimenez PC, Rimal B, Patterson AD, Traxler MF, de Cassia Pessotti R, Alvarado-Villalobos D, Tamayo-Castillo G, Chaverri P, Escudero-Leyva E, Quiros-Guerrero LM, Bory AJ, Joubert J, Rutz A, Wolfender JL, Allard PM, Sichert A, Pontrelli S, Pullman BS, Bandeira N, Gerwick WH, Gindro K, Massana-Codina J, Wagner BC, Forchhammer K, Petras D, Aiosa N, Garg N, Liebeke M, Bourceau P, Kang KB, Gadhavi H, de Carvalho LPS, Dos Santos MS, Pérez-Lorente AI, Molina-Santiago C, Romero D, Franke R, Brönstrup M, de León AVP, Pope PB, Rosa SL, Barbera G, Roager HM, Laursen MF, Hammerle F, Siewert B, Peintner U, Licona-Cassani C, Rodriguez-Orduña L, Rampler E, Hildebrand F, Koellensperger G, Schoeny H, Hohenwallner K, Panzenboeck L, Gregor R, O'Neill EC, Roxborough ET, Odoi J, Bale NJ, Ding S, Sinninghe Damsté JS, Guan XL, Cui JJ, Ju KS, Silva DB, Silva FMR, da Silva GF, Koolen HHF, Grundmann C, Clement JA, Mohimani H, Broders K, McPhail KL, Ober-Singleton SE, Rath CM, McDonald D, Knight R, Wang M, Dorrestein PC | Research square | 37577622 | Res Sq | 2023 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/37577622 |
MS2Planner: improved fragmentation spectra coverage in untargeted mass spectrometry by iterative optimized data acquisition. | Zuo Z, Cao L, Nothia LF, Mohimani H | Bioinformatics (Oxford, England) | 34252948 | Bioinformatics | 2021 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/34252948 |
Large scale sequence alignment via efficient inference in generative models. | Mongia M, Shen C, Davoodi AG, Marçais G, Mohimani H | Scientific reports | 37142645 | Sci Rep | 2023 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/37142645 |
EnHiC: learning fine-resolution Hi-C contact maps using a generative adversarial framework. | Hu Y, Ma W | Bioinformatics (Oxford, England) | 34252966 | Bioinformatics | 2021 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/34252966 |
MolDiscovery: learning mass spectrometry fragmentation of small molecules. | Cao L, Guler M, Tagirdzhanov A, Lee YY, Gurevich A, Mohimani H | Nature communications | 34140479 | Nat Commun | 2021 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/34140479 |
A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens. | Guna A, Page KR, Replogle JM, Esantsi TK, Wang ML, Weissman JS, Voorhees RM | bioRxiv : the preprint server for biology | 36711738 | bioRxiv | 2023 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/36711738 |
A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens. | Guna A, Page KR, Replogle JM, Esantsi TK, Wang ML, Weissman JS, Voorhees RM | BMC genomics | 37904134 | BMC Genomics | 2023 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/37904134 |
Structural basis for membrane insertion by the human ER membrane protein complex. | Pleiner T, Tomaleri GP, Januszyk K, Inglis AJ, Hazu M, Voorhees RM | Science (New York, N.Y.) | 32439656 | Science | 2020 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/32439656 |
A TAle of Two Pathways: Tail-Anchored Protein Insertion at the Endoplasmic Reticulum. | Guna A, Hazu M, Pinton Tomaleri G, Voorhees RM | Cold Spring Harbor perspectives in biology | 36041783 | Cold Spring Harb Perspect Biol | 2023 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/36041783 |
A nanobody-based strategy for rapid and scalable purification of human protein complexes. | Stevens TA, Tomaleri GP, Hazu M, Wei S, Nguyen VN, DeKalb C, Voorhees RM, Pleiner T | Nature protocols | 37974029 | Nat Protoc | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/37974029 |
A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER. | Pleiner T, Hazu M, Pinton Tomaleri G, Nguyen VN, Januszyk K, Voorhees RM | The Journal of cell biology | 37199759 | J Cell Biol | 2023 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/37199759 |
WNK1 is an assembly factor for the human ER membrane protein complex. | Pleiner T, Hazu M, Tomaleri GP, Januszyk K, Oania RS, Sweredoski MJ, Moradian A, Guna A, Voorhees RM | Molecular cell | 33964204 | Mol Cell | 2021 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/33964204 |
Differential Modes of Orphan Subunit Recognition for the WRB/CAML Complex. | Inglis AJ, Page KR, Guna A, Voorhees RM | Cell reports | 32187542 | Cell Rep | 2020 Mar 17 | https://www.ncbi.nlm.nih.gov/pubmed/32187542 |
u-track3D: Measuring, navigating, and validating dense particle trajectories in three dimensions. | Roudot P, Legant WR, Zou Q, Dean KM, Isogai T, Welf ES, David AF, Gerlich DW, Fiolka R, Betzig E, Danuser G | Cell reports methods | 38042149 | Cell Rep Methods | 2023 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/38042149 |
Smart lattice light-sheet microscopy for imaging rare and complex cellular events. | Shi Y, Tabet JS, Milkie DE, Daugird TA, Yang CQ, Ritter AT, Giovannucci A, Legant WR | Nature methods | 38167656 | Nat Methods | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38167656 |
Posterior approach to correct for focal plane offsets in lattice light-sheet structured illumination microscopy. | Shi Y, Daugird TA, Legant WR | Journal of biomedical optics | 39086928 | J Biomed Opt | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/39086928 |
Shared and redundant proteins coordinate signal cross-talk between MAPK pathways in yeast. | Zhang S, Wang H, Sipko EL, Li S, Daugird TA, Legant WR, Dohlman HG | Molecular biology of the cell | 39083355 | Mol Biol Cell | 2024 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/39083355 |
A series of spontaneously blinking dyes for super-resolution microscopy. | Holland KL, Plutkis SE, Daugird TA, Sau A, Grimm JB, English BP, Zheng Q, Dave S, Rahman F, Xie L, Dong P, Tkachuk AN, Brown TA, Singer RH, Liu Z, Galbraith CG, Musser SM, Legant WR, Lavis LD | bioRxiv : the preprint server for biology | 38766149 | bioRxiv | 2024 Feb 24 | https://www.ncbi.nlm.nih.gov/pubmed/38766149 |
A quantitative analysis of various patterns applied in lattice light sheet microscopy. | Shi Y, Daugird TA, Legant WR | Nature communications | 35941165 | Nat Commun | 2022 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/35941165 |
Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment. | Daugird TA, Shi Y, Holland KL, Rostamian H, Liu Z, Lavis LD, Rodriguez J, Strahl BD, Legant WR | Nature communications | 38755200 | Nat Commun | 2024 May 16 | https://www.ncbi.nlm.nih.gov/pubmed/38755200 |
Phase separation drives aberrant chromatin looping and cancer development. | Ahn JH, Davis ES, Daugird TA, Zhao S, Quiroga IY, Uryu H, Li J, Storey AJ, Tsai YH, Keeley DP, Mackintosh SG, Edmondson RD, Byrum SD, Cai L, Tackett AJ, Zheng D, Legant WR, Phanstiel DH, Wang GG | Nature | 34163069 | Nature | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34163069 |
Deep learning enables fast and dense single-molecule localization with high accuracy. | Speiser A, Müller LR, Hoess P, Matti U, Obara CJ, Legant WR, Kreshuk A, Macke JH, Ries J, Turaga SC | Nature methods | 34480155 | Nat Methods | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34480155 |
3D ATAC-PALM: super-resolution imaging of the accessible genome. | Xie L, Dong P, Chen X, Hsieh TS, Banala S, De Marzio M, English BP, Qi Y, Jung SK, Kieffer-Kwon KR, Legant WR, Hansen AS, Schulmann A, Casellas R, Zhang B, Betzig E, Lavis LD, Chang HY, Tjian R, Liu Z | Nature methods | 32203384 | Nat Methods | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32203384 |
A multi-functional microfluidic device compatible with widefield and light sheet microscopy. | Moore RP, O'Shaughnessy EC, Shi Y, Nogueira AT, Heath KM, Hahn KM, Legant WR | Lab on a chip | 34859808 | Lab Chip | 2021 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/34859808 |
Superresolution microscopy reveals actomyosin dynamics in medioapical arrays. | Moore RP, Fogerson SM, Tulu US, Yu JW, Cox AH, Sican MA, Li D, Legant WR, Weigel AV, Crawford JM, Betzig E, Kiehart DP | Molecular biology of the cell | 35544300 | Mol Biol Cell | 2022 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/35544300 |
Cell dynamics revealed by microscopy advances. | Hockenberry MA, Daugird TA, Legant WR | Current opinion in cell biology | 39159598 | Curr Opin Cell Biol | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39159598 |
Mapping the nuclear landscape with multiplexed super-resolution fluorescence microscopy. | Rahman F, Augoustides V, Tyler E, Daugird TA, Arthur C, Legant WR | bioRxiv : the preprint server for biology | 39211261 | bioRxiv | 2024 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/39211261 |
Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite. | Park SY, Rao C, Coyte KZ, Kuziel GA, Zhang Y, Huang W, Franzosa EA, Weng JK, Huttenhower C, Rakoff-Nahoum S | Cell | 35120663 | Cell | 2022 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/35120663 |
Innate immune Galectin-7 specifically targets microbes that decorate themselves in blood group-like antigens. | Wu SC, Kamili NA, Dias-Baruffi M, Josephson CD, Rathgeber MF, Yeung MY, Lane WJ, Wang J, Jan HM, Rakoff-Nahoum S, Cummings RD, Stowell SR, Arthur CM | iScience | 35754739 | iScience | 2022 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/35754739 |
Galectin-4 Antimicrobial Activity Primarily Occurs Through its C-Terminal Domain. | Jan HM, Wu SC, Stowell CJ, Vallecillo-Zúniga ML, Paul A, Patel KR, Muthusamy S, Lin HY, Ayona D, Jajosky RP, Varadkar SP, Nakahara H, Chan R, Bhave D, Lane WJ, Yeung MY, Hollenhorst MA, Rakoff-Nahoum S, Cummings RD, Arthur CM, Stowell SR | Molecular & cellular proteomics : MCP | 38490531 | Mol Cell Proteomics | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38490531 |
RELMβ sets the threshold for microbiome-dependent oral tolerance. | Stephen-Victor E, Kuziel GA, Martinez-Blanco M, Jugder BE, Benamar M, Wang Z, Chen Q, Lozano GL, Abdel-Gadir A, Cui Y, Fong J, Saint-Denis E, Chang I, Nadeau KC, Phipatanakul W, Zhang A, Farraj FA, Holder-Niles F, Zeve D, Breault DT, Schmitz-Abe K, Rachid R, Crestani E, Rakoff-Nahoum S, Chatila TA | Nature | 39843735 | Nature | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39843735 |
Ecological rules for the assembly of microbiome communities. | Coyte KZ, Rao C, Rakoff-Nahoum S, Foster KR | PLoS biology | 33606675 | PLoS Biol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33606675 |
Multi-kingdom ecological drivers of microbiota assembly in preterm infants. | Rao C, Coyte KZ, Bainter W, Geha RS, Martin CR, Rakoff-Nahoum S | Nature | 33627867 | Nature | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33627867 |
Bacterial amylases enable glycogen degradation by the vaginal microbiome. | Jenkins DJ, Woolston BM, Hood-Pishchany MI, Pelayo P, Konopaski AN, Quinn Peters M, France MT, Ravel J, Mitchell CM, Rakoff-Nahoum S, Whidbey C, Balskus EP | Nature microbiology | 37563289 | Nat Microbiol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37563289 |
S. pombe wtf drivers use dual transcriptional regulation and selective protein exclusion from spores to cause meiotic drive. | Nuckolls NL, Nidamangala Srinivasa A, Mok AC, Helston RM, Bravo Núñez MA, Lange JJ, Gallagher TJ, Seidel CW, Zanders SE | PLoS genetics | 36477651 | PLoS Genet | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36477651 |
wtf genes are prolific dual poison-antidote meiotic drivers. | Nuckolls NL, Bravo Núñez MA, Eickbush MT, Young JM, Lange JJ, Yu JS, Smith GR, Jaspersen SL, Malik HS, Zanders SE | eLife | 28631612 | Elife | 2017 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/28631612 |
Veni, vidi, vici: the success of wtf meiotic drivers in fission yeast. | López Hernández JF, Zanders SE | Yeast (Chichester, England) | 29322557 | Yeast | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29322557 |
A suppressor of a wtf poison-antidote meiotic driver acts via mimicry of the driver's antidote. | Bravo Núñez MA, Lange JJ, Zanders SE | PLoS genetics | 30475921 | PLoS Genet | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30475921 |
A family of killers. | De Carvalho M, Zanders SE | eLife | 31347501 | Elife | 2019 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/31347501 |
Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogen Cryptococcus neoformans. | Billmyre RB, Craig CJ, Lyon J, Reichardt C, Eickbush MT, Zanders SE | bioRxiv : the preprint server for biology | 39131341 | bioRxiv | 2024 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/39131341 |
Meiotic drive. | Srinivasa AN, Zanders SE | Current biology : CB | 32516606 | Curr Biol | 2020 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/32516606 |
Dramatically diverse Schizosaccharomyces pombe wtf meiotic drivers all display high gamete-killing efficiency. | Bravo Núñez MA, Sabbarini IM, Eickbush MT, Liang Y, Lange JJ, Kent AM, Zanders SE | PLoS genetics | 32032353 | PLoS Genet | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32032353 |
Molecular Mechanisms and Evolutionary Consequences of Spore Killers in Ascomycetes. | Zanders S, Johannesson H | Microbiology and molecular biology reviews : MMBR | 34756084 | Microbiol Mol Biol Rev | 2021 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/34756084 |
Chromosome segregation: human female meiosis breaks all the rules. | Zanders SE, Malik HS | Current biology : CB | 26241139 | Curr Biol | 2015 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/26241139 |
Atypical meiosis can be adaptive in outcrossed Schizosaccharomyces pombe due to wtf meiotic drivers. | Bravo Núñez MA, Sabbarini IM, Eide LE, Unckless RL, Zanders SE | eLife | 32790622 | Elife | 2020 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/32790622 |
Diverse mating phenotypes impact the spread of wtf meiotic drivers in Schizosaccharomyces pombe. | López Hernández JF, Helston RM, Lange JJ, Billmyre RB, Schaffner SH, Eickbush MT, McCroskey S, Zanders SE | eLife | 34895466 | Elife | 2021 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/34895466 |
The wtf meiotic driver gene family has unexpectedly persisted for over 100 million years. | De Carvalho M, Jia GS, Nidamangala Srinivasa A, Billmyre RB, Xu YH, Lange JJ, Sabbarini IM, Du LL, Zanders SE | eLife | 36227631 | Elife | 2022 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/36227631 |
Modeling the evolution of Schizosaccharomyces pombe populations with multiple killer meiotic drivers. | López Hernández JF, Rubinstein BY, Unckless RL, Zanders SE | G3 (Bethesda, Md.) | 38938172 | G3 (Bethesda) | 2024 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/38938172 |
Functional constraints of wtf killer meiotic drivers. | Nidamangala Srinivasa A, Campbell S, Venkatesan S, Nuckolls NL, Lange JJ, Halfmann R, Zanders SE | PLoS genetics | 39965018 | PLoS Genet | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39965018 |
The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death. | Nuckolls NL, Mok AC, Lange JJ, Yi K, Kandola TS, Hunn AM, McCroskey S, Snyder JL, Bravo Núñez MA, McClain M, McKinney SA, Wood C, Halfmann R, Zanders SE | eLife | 33108274 | Elife | 2020 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/33108274 |
Gene conversion generates evolutionary novelty that fuels genetic conflicts. | Daugherty MD, Zanders SE | Current opinion in genetics & development | 31466040 | Curr Opin Genet Dev | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31466040 |
Genome-wide quantification of contributions to sexual fitness identifies genes required for spore viability and health in fission yeast. | Billmyre RB, Eickbush MT, Craig CJ, Lange JJ, Wood C, Helston RM, Zanders SE | PLoS genetics | 36301993 | PLoS Genet | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36301993 |
What can we learn from selfish loci that break Mendel's law? | Zanders SE | PLoS biology | 35853012 | PLoS Biol | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35853012 |
Genetic Villains: Killer Meiotic Drivers. | Bravo Núñez MA, Nuckolls NL, Zanders SE | Trends in genetics : TIG | 29499907 | Trends Genet | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29499907 |
Killer Meiotic Drive and Dynamic Evolution of the wtf Gene Family. | Eickbush MT, Young JM, Zanders SE | Molecular biology and evolution | 30991417 | Mol Biol Evol | 2019 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/30991417 |
Fertility Costs of Meiotic Drivers. | Zanders SE, Unckless RL | Current biology : CB | 31163165 | Curr Biol | 2019 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/31163165 |
Structural elements promote architectural stripe formation and facilitate ultra-long-range gene regulation at a human disease locus. | Chen LF, Long HK, Park M, Swigut T, Boettiger AN, Wysocka J | Molecular cell | 36996812 | Mol Cell | 2023 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/36996812 |
Advances in Chromatin Imaging at Kilobase-Scale Resolution. | Boettiger A, Murphy S | Trends in genetics : TIG | 32007290 | Trends Genet | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32007290 |
Tracing DNA paths and RNA profiles in cultured cells and tissues with ORCA. | Mateo LJ, Sinnott-Armstrong N, Boettiger AN | Nature protocols | 33619390 | Nat Protoc | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33619390 |
How subtle changes in 3D structure can create large changes in transcription. | Xiao JY, Hafner A, Boettiger AN | eLife | 34240703 | Elife | 2021 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/34240703 |
mSWI/SNF promotes Polycomb repression both directly and through genome-wide redistribution. | Weber CM, Hafner A, Kirkland JG, Braun SMG, Stanton BZ, Boettiger AN, Crabtree GR | Nature structural & molecular biology | 34117481 | Nat Struct Mol Biol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34117481 |
Deep learning connects DNA traces to transcription to reveal predictive features beyond enhancer-promoter contact. | Rajpurkar AR, Mateo LJ, Murphy SE, Boettiger AN | Nature communications | 34103507 | Nat Commun | 2021 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/34103507 |
Visualizing DNA folding and RNA in embryos at single-cell resolution. | Mateo LJ, Murphy SE, Hafner A, Cinquini IS, Walker CA, Boettiger AN | Nature | 30886393 | Nature | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30886393 |
Loop stacking organizes genome folding from TADs to chromosomes. | Hafner A, Park M, Berger SE, Murphy SE, Nora EP, Boettiger AN | Molecular cell | 37146570 | Mol Cell | 2023 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/37146570 |
Engineering control circuits for molecular robots using synthetic biology. | Wei TY, Ruder WC | APL materials | 33101786 | APL Mater | 2020 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/33101786 |
The Future Application of Organ-on-a-Chip Technologies as Proving Grounds for MicroBioRobots. | Fuller HC, Wei TY, Behrens MR, Ruder WC | Micromachines | 33092054 | Micromachines (Basel) | 2020 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/33092054 |
An embedded microfluidic valve for dynamic control of cellular communication. | DeAngelis MA, Ruder WC, LeDuc PR | Applied physics letters | 38094664 | Appl Phys Lett | 2023 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/38094664 |
Smart Magnetic Microrobots Learn to Swim with Deep Reinforcement Learning. | Behrens MR, Ruder WC | Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) | 38463142 | Adv Intell Syst | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38463142 |
Open-source, 3D-printed Peristaltic Pumps for Small Volume Point-of-Care Liquid Handling. | Behrens MR, Fuller HC, Swist ER, Wu J, Islam MM, Long Z, Ruder WC, Steward R Jr | Scientific reports | 32005961 | Sci Rep | 2020 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/32005961 |
Listeria monocytogenes requires cellular respiration for NAD(+) regeneration and pathogenesis. | Rivera-Lugo R, Deng D, Anaya-Sanchez A, Tejedor-Sanz S, Tang E, Reyes Ruiz VM, Smith HB, Titov DV, Sauer JD, Skaar EP, Ajo-Franklin CM, Portnoy DA, Light SH | eLife | 35380108 | Elife | 2022 Apr 5 | https://www.ncbi.nlm.nih.gov/pubmed/35380108 |
Genetically encoded tool for manipulation of ΔΨm identifies the latter as the driver of integrative stress response induced by ATP Synthase dysfunction. | Choe M, Titov DV | bioRxiv : the preprint server for biology | 38234735 | bioRxiv | 2023 Dec 27 | https://www.ncbi.nlm.nih.gov/pubmed/38234735 |
Physical bioenergetics: Energy fluxes, budgets, and constraints in cells. | Yang X, Heinemann M, Howard J, Huber G, Iyer-Biswas S, Le Treut G, Lynch M, Montooth KL, Needleman DJ, Pigolotti S, Rodenfels J, Ronceray P, Shankar S, Tavassoly I, Thutupalli S, Titov DV, Wang J, Foster PJ | Proceedings of the National Academy of Sciences of the United States of America | 34140336 | Proc Natl Acad Sci U S A | 2021 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/34140336 |
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell. | Mick E, Titov DV, Skinner OS, Sharma R, Jourdain AA, Mootha VK | eLife | 32463360 | Elife | 2020 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/32463360 |
The Warburg Effect is the result of faster ATP production by glycolysis than respiration. | Kukurugya MA, Rosset S, Titov DV | Proceedings of the National Academy of Sciences of the United States of America | 39514306 | Proc Natl Acad Sci U S A | 2024 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/39514306 |
SRS microscopy identifies inhibition of vitellogenesis as a mediator of lifespan extension by caloric restriction in C. elegans. | Yang B, Manifold B, Han W, DeSousa C, Zhu W, Streets A, Titov DV | bioRxiv : the preprint server for biology | 40034647 | bioRxiv | 2025 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/40034647 |
Genetically encoded tools for measuring and manipulating metabolism. | Choe M, Titov DV | Nature chemical biology | 35484256 | Nat Chem Biol | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35484256 |
Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model. | Hoye ML, Calviello L, Poff AJ, Ejimogu NE, Newman CR, Montgomery MD, Ou J, Floor SN, Silver DL | eLife | 35762573 | Elife | 2022 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/35762573 |
Lysate and cell-based assays to probe the translational role of RNA helicases. | Wilkins KC, Venkataramanan S, Floor SN | Methods in enzymology | 35965005 | Methods Enzymol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35965005 |
Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. | Lennox AL, Hoye ML, Jiang R, Johnson-Kerner BL, Suit LA, Venkataramanan S, Sheehan CJ, Alsina FC, Fregeau B, Aldinger KA, Moey C, Lobach I, Afenjar A, Babovic-Vuksanovic D, Bézieau S, Blackburn PR, Bunt J, Burglen L, Campeau PM, Charles P, Chung BHY, Cogné B, Curry C, D'Agostino MD, Di Donato N, Faivre L, Héron D, Innes AM, Isidor B, Keren B, Kimball A, Klee EW, Kuentz P, Küry S, Martin-Coignard D, Mirzaa G, Mignot C, Miyake N, Matsumoto N, Fujita A, Nava C, Nizon M, Rodriguez D, Blok LS, Thauvin-Robinet C, Thevenon J, Vincent M, Ziegler A, Dobyns W, Richards LJ, Barkovich AJ, Floor SN, Silver DL, Sherr EH | Neuron | 32135084 | Neuron | 2020 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/32135084 |
DDX3X and DDX3Y are redundant in protein synthesis. | Venkataramanan S, Gadek M, Calviello L, Wilkins K, Floor SN | RNA (New York, N.Y.) | 34535544 | RNA | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34535544 |
Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression. | Campbell AE, Dyle MC, Albanese R, Matheny T, Sudheendran K, Cortázar MA, Forman T, Fu R, Gillen AE, Caruthers MH, Floor SN, Calviello L, Jagannathan S | Cell reports | 37314931 | Cell Rep | 2023 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/37314931 |
A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response. | Subramanian A, Wang L, Moss T, Voorhies M, Sangwan S, Stevenson E, Pulido EH, Kwok S, Chalkley RJ, Li KH, Krogan NJ, Swaney DL, Burlingame AL, Floor SN, Sil A, Walter P, Mukherjee S | Nature cell biology | 37857833 | Nat Cell Biol | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37857833 |
Control of ribosomal protein synthesis by the Microprocessor complex. | Jiang X, Prabhakar A, Van der Voorn SM, Ghatpande P, Celona B, Venkataramanan S, Calviello L, Lin C, Wang W, Black BL, Floor SN, Lagna G, Hata A | Science signaling | 33622983 | Sci Signal | 2021 Feb 23 | https://www.ncbi.nlm.nih.gov/pubmed/33622983 |
RNA molecular recording with an engineered RNA deaminase. | Lin Y, Kwok S, Hein AE, Thai BQ, Alabi Y, Ostrowski MS, Wu K, Floor SN | Nature methods | 37857907 | Nat Methods | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37857907 |
A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X. | Jowhar Z, Xu A, Venkataramanan S, Dossena F, Hoye ML, Silver DL, Floor SN, Calviello L | Molecular systems biology | 38273160 | Mol Syst Biol | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38273160 |
DDX3 depletion represses translation of mRNAs with complex 5' UTRs. | Calviello L, Venkataramanan S, Rogowski KJ, Wyler E, Wilkins K, Tejura M, Thai B, Krol J, Filipowicz W, Landthaler M, Floor SN | Nucleic acids research | 33905506 | Nucleic Acids Res | 2021 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/33905506 |
A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X. | Jowhar Z, Xu A, Venkataramanan S, Dossena F, Hoye ML, Silver DL, Floor SN, Calviello L | bioRxiv : the preprint server for biology | 37214951 | bioRxiv | 2023 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/37214951 |
Calcium-triggered DNA-mediated membrane fusion in synthetic cells. | Hsu YY, Chen SJ, Bernal-Chanchavac J, Sharma B, Moghimianavval H, Stephanopoulos N, Liu AP | bioRxiv : the preprint server for biology | 37205334 | bioRxiv | 2023 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/37205334 |
Bioactive Fibronectin-III(10)-DNA Origami Nanofibers Promote Cell Adhesion and Spreading. | Buchberger A, Riker K, Bernal-Chanchavac J, Narayanan RP, Simmons CR, Fahmi NE, Freeman R, Stephanopoulos N | ACS applied bio materials | 36108278 | ACS Appl Bio Mater | 2022 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/36108278 |
Proximity-enhanced synthesis of DNA-peptide-DNA triblock molecules. | MacCulloch T, Novacek A, Stephanopoulos N | Chemical communications (Cambridge, England) | 35260875 | Chem Commun (Camb) | 2022 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/35260875 |
Construction and reconfiguration of dynamic DNA origami assemblies with coiled-coil patches and patterns. | Teng T, Bernal-Chanchavac J, Stephanopoulos N, Castro CE | bioRxiv : the preprint server for biology | 37790447 | bioRxiv | 2023 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/37790447 |
DNA-Nanostructure-Guided Assembly of Proteins into Programmable Shapes. | Lu Q, Xu Y, Poppleton E, Zhou K, Sulc P, Stephanopoulos N, Ke Y | Nano letters | 38278134 | Nano Lett | 2024 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/38278134 |
Coarse-Grained Simulations for the Characterization and Optimization of Hybrid Protein-DNA Nanostructures. | Narayanan RP, Procyk J, Nandi P, Prasad A, Xu Y, Poppleton E, Williams D, Zhang F, Yan H, Chiu PL, Stephanopoulos N, Šulc P | ACS nano | 35980981 | ACS Nano | 2022 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/35980981 |
The interactions between DNA nanostructures and cells: A critical overview from a cell biology perspective. | Frtús A, Smolková B, Uzhytchak M, Lunova M, Jirsa M, Henry SJW, Dejneka A, Stephanopoulos N, Lunov O | Acta biomaterialia | 35523414 | Acta Biomater | 2022 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/35523414 |
Calcium-triggered DNA-mediated membrane fusion in synthetic cells. | Hsu YY, Chen SJ, Bernal-Chanchavac J, Sharma B, Moghimianavval H, Stephanopoulos N, Liu AP | Chemical communications (Cambridge, England) | 37365952 | Chem Commun (Camb) | 2023 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/37365952 |
Structure-based discovery of hydrocarbon-stapled paxillin peptides that block FAK scaffolding in cancer. | Reyes L, Naser L, Weiner WS, Thifault D, Stahl E, McCreary L, Nott R, Quick C, Buchberger A, Alvarado C, Rivera A, Miller JA, Khatiwala R, Cherry BR, Nelson R, Martin-Garcia JM, Stephanopoulos N, Fromme R, Fromme P, Cance W, Marlowe T | Nature communications | 40021642 | Nat Commun | 2025 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/40021642 |
Nanoscale Structures and Materials from the Self-assembly of Polypeptides and DNA. | Bernal-Chanchavac J, Al-Amin M, Stephanopoulos N | Current topics in medicinal chemistry | 34911426 | Curr Top Med Chem | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/34911426 |
Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals. | Simmons CR, Buchberger A, Henry SJW, Novacek A, Fahmi NE, MacCulloch T, Stephanopoulos N, Yan H | Journal of the American Chemical Society | 37987645 | J Am Chem Soc | 2023 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/37987645 |
Self-Assembly of Hybrid Peptide-DNA Nanostructures using Homotrimeric Coiled-Coil/Nucleic Acid Building Blocks. | Buchberger A, Al-Amin M, Simmons CR, Stephanopoulos N | Chembiochem : a European journal of chemical biology | 37099451 | Chembiochem | 2023 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/37099451 |
Geometrically constrained cytoskeletal reorganisation modulates DNA nanostructures uptake. | Elblová P, Andělová H, Lunova M, Anthi J, Henry SJW, Tu X, Dejneka A, Jirsa M, Stephanopoulos N, Lunov O | Journal of materials chemistry. B | 39835937 | J Mater Chem B | 2025 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/39835937 |
Functionalizing DNA nanostructures for therapeutic applications. | Henry SJW, Stephanopoulos N | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 34008347 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34008347 |
Protein Corona Inhibits Endosomal Escape of Functionalized DNA Nanostructures in Living Cells. | Smolková B, MacCulloch T, Rockwood TF, Liu M, Henry SJW, Frtús A, Uzhytchak M, Lunova M, Hof M, Jurkiewicz P, Dejneka A, Stephanopoulos N, Lunov O | ACS applied materials & interfaces | 34569777 | ACS Appl Mater Interfaces | 2021 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/34569777 |
CytoDirect: A Nucleic Acid Nanodevice for Specific and Efficient Delivery of Functional Payloads to the Cytoplasm. | Yu L, Xu Y, Al-Amin M, Jiang S, Sample M, Prasad A, Stephanopoulos N, Šulc P, Yan H | Journal of the American Chemical Society | 38055928 | J Am Chem Soc | 2023 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/38055928 |
High-Affinity Host-Guest Recognition for Efficient Assembly and Enzymatic Responsiveness of DNA Nanostructures. | Narayanan RP, Prasad A, Buchberger A, Zou L, Bernal-Chanchavac J, MacCulloch T, Fahmi NE, Yan H, Zhang F, Webber MJ, Stephanopoulos N | Small (Weinheim an der Bergstrasse, Germany) | 37849034 | Small | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/37849034 |
Construction of Reconfigurable and Polymorphic DNA Origami Assemblies with Coiled-Coil Patches and Patterns. | Teng T, Bernal-Chanchavac J, Stephanopoulos N, Castro CE | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 38459678 | Adv Sci (Weinh) | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38459678 |
Using dynamic biomaterials to study the temporal role of bioactive peptides during osteogenesis. | Fumasi FM, MacCulloch T, Bernal-Chanchavac J, Stephanopoulos N, Holloway JL | Biomaterials advances | 38096646 | Biomater Adv | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38096646 |
Peptide-coated DNA nanostructures as a platform for control of lysosomal function in cells. | Elblová P, Lunova M, Henry SJW, Tu X, Calé A, Dejneka A, Havelková J, Petrenko Y, Jirsa M, Stephanopoulos N, Lunov O | Chemical engineering journal (Lausanne, Switzerland : 1996) | 39372137 | Chem Eng J | 2024 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/39372137 |
Site-specific arrangement and structure determination of minor groove binding molecules in self-assembled three-dimensional DNA crystals. | Simmons CR, Buchberger A, Henry SJW, Novacek A, Fahmi NE, MacCulloch T, Stephanopoulos N, Yan H | bioRxiv : the preprint server for biology | 37873139 | bioRxiv | 2023 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/37873139 |
C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression. | Sun Y, Eshov A, Zhou J, Isiktas AU, Guo JU | Nature communications | 32620797 | Nat Commun | 2020 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/32620797 |
Coding functions of "noncoding" RNAs. | Wei LH, Guo JU | Science (New York, N.Y.) | 32139529 | Science | 2020 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/32139529 |
Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions. | Lee PJ, Sun Y, Soares AR, Fai C, Picciotto MR, Guo JU | Molecular cell | 39317199 | Mol Cell | 2024 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/39317199 |
Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting. | Sun Y, Abriola L, Niederer RO, Pedersen SF, Alfajaro MM, Silva Monteiro V, Wilen CB, Ho YC, Gilbert WV, Surovtseva YV, Lindenbach BD, Guo JU | Proceedings of the National Academy of Sciences of the United States of America | 34185680 | Proc Natl Acad Sci U S A | 2021 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/34185680 |
Aberrant splicing exonizes C9ORF72 repeat expansion in ALS/FTD. | Yang S, Wijegunawardana D, Sheth U, Veire AM, Salgado JMS, Agrawal M, Zhou J, Pereira JD, Gendron TF, Guo JU | bioRxiv : the preprint server for biology | 38014069 | bioRxiv | 2023 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/38014069 |
Systematic generation and imaging of tandem repeats reveal base-pairing properties that promote RNA aggregation. | Isiktas AU, Eshov A, Yang S, Guo JU | Cell reports methods | 36452875 | Cell Rep Methods | 2022 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/36452875 |
Regulation of nonsense-mediated mRNA decay in neural development and disease. | Lee PJ, Yang S, Sun Y, Guo JU | Journal of molecular cell biology | 33783512 | J Mol Cell Biol | 2021 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/33783512 |
Stress promotes RNA G-quadruplex folding in human cells. | Kharel P, Fay M, Manasova EV, Anderson PJ, Kurkin AV, Guo JU, Ivanov P | Nature communications | 36639366 | Nat Commun | 2023 Jan 13 | https://www.ncbi.nlm.nih.gov/pubmed/36639366 |
Restriction of SARS-CoV-2 Replication by Targeting Programmed -1 Ribosomal Frameshifting In Vitro. | Sun Y, Abriola L, Surovtseva YV, Lindenbach BD, Guo JU | bioRxiv : the preprint server for biology | 33106809 | bioRxiv | 2020 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/33106809 |
Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions. | Lee PJ, Soares AR, Sun Y, Fai C, Picciotto MR, Guo JU | bioRxiv : the preprint server for biology | 38405936 | bioRxiv | 2024 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/38405936 |
Internal sensory neurons regulate stage-specific growth in Drosophila. | Ohhara Y, Yamanaka N | Development (Cambridge, England) | 36227580 | Development | 2022 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/36227580 |
Steroid Hormone Entry into the Brain Requires a Membrane Transporter in Drosophila. | Okamoto N, Yamanaka N | Current biology : CB | 31928869 | Curr Biol | 2020 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/31928869 |
Essential functions of mosquito ecdysone importers in development and reproduction. | Hun LV, Okamoto N, Imura E, Maxson R, Bittar R, Yamanaka N | Proceedings of the National Academy of Sciences of the United States of America | 35696563 | Proc Natl Acad Sci U S A | 2022 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/35696563 |
Steroid hormone signaling: What we can learn from insect models. | Okamoto N, Fujinaga D, Yamanaka N | Vitamins and hormones | 37717997 | Vitam Horm | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37717997 |
Functional characterization of eicosanoid signaling in Drosophila development. | Fujinaga D, Nolan C, Yamanaka N | bioRxiv : the preprint server for biology | 39868285 | bioRxiv | 2025 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/39868285 |
A Neuropeptide Signaling Network That Regulates Developmental Timing and Systemic Growth in Drosophila. | Ohhara Y, Blick M, Park D, Yoon SE, Kim YJ, Pankratz MJ, O'Connor MB, Yamanaka N | The Journal of comparative neurology | 39415613 | J Comp Neurol | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39415613 |
Deep mutational scanning and machine learning reveal structural and molecular rules governing allosteric hotspots in homologous proteins. | Leander M, Liu Z, Cui Q, Raman S | eLife | 36226916 | Elife | 2022 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/36226916 |
De novo design of programmable inducible promoters. | Liu X, Gupta STP, Bhimsaria D, Reed JL, Rodríguez-Martínez JA, Ansari AZ, Raman S | Nucleic acids research | 31552424 | Nucleic Acids Res | 2019 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/31552424 |
A parametrized two-domain thermodynamic model explains diverse mutational effects on protein allostery. | Liu Z, Gillis T, Raman S, Cui Q | bioRxiv : the preprint server for biology | 37662419 | bioRxiv | 2024 Feb 14 | https://www.ncbi.nlm.nih.gov/pubmed/37662419 |
Large-scale discovery of chromatin dysregulation induced by oncofusions and other protein-coding variants. | Frenkel M, Corban JE, Hujoel MLA, Morris Z, Raman S | Nature biotechnology | 39048711 | Nat Biotechnol | 2024 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/39048711 |
Functional plasticity and evolutionary adaptation of allosteric regulation. | Leander M, Yuan Y, Meger A, Cui Q, Raman S | Proceedings of the National Academy of Sciences of the United States of America | 32999067 | Proc Natl Acad Sci U S A | 2020 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/32999067 |
Discovering chromatin dysregulation induced by protein-coding perturbations at scale. | Frenkel M, Hujoel MLA, Morris Z, Raman S | bioRxiv : the preprint server for biology | 37781603 | bioRxiv | 2023 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/37781603 |
Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors. | Meger AT, Spence MA, Sandhu M, Matthews D, Chen J, Jackson CJ, Raman S | Cell systems | 38537640 | Cell Syst | 2024 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/38537640 |
A parameterized two-domain thermodynamic model explains diverse mutational effects on protein allostery. | Liu Z, Gillis TG, Raman S, Cui Q | eLife | 38836839 | Elife | 2024 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/38836839 |
Multidimensional super-resolution microscopy unveils nanoscale surface aggregates in the aging of FUS condensates. | He C, Wu CY, Li W, Xu K | bioRxiv : the preprint server for biology | 37503034 | bioRxiv | 2023 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/37503034 |
Single-Molecule Displacement Mapping Unveils Sign-Asymmetric Protein Charge Effects on Intraorganellar Diffusion. | Xiang L, Yan R, Chen K, Li W, Xu K | Nano letters | 36802676 | Nano Lett | 2023 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/36802676 |
Probing Nanoscale Diffusional Heterogeneities in Cellular Membranes through Multidimensional Single-Molecule and Super-Resolution Microscopy. | Yan R, Chen K, Xu K | Journal of the American Chemical Society | 33084318 | J Am Chem Soc | 2020 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/33084318 |
The endoplasmic reticulum adopts two distinct tubule forms. | Wang B, Zhao Z, Xiong M, Yan R, Xu K | Proceedings of the National Academy of Sciences of the United States of America | 35471903 | Proc Natl Acad Sci U S A | 2022 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/35471903 |
Single-Molecule Spectroscopy and Super-Resolution Mapping of Physicochemical Parameters in Living Cells. | Steves MA, He C, Xu K | Annual review of physical chemistry | 38360526 | Annu Rev Phys Chem | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38360526 |
Single-molecule displacement mapping unveils nanoscale heterogeneities in intracellular diffusivity. | Xiang L, Chen K, Yan R, Li W, Xu K | Nature methods | 32203387 | Nat Methods | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32203387 |
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis. | Tian R, Abarientos A, Hong J, Hashemi SH, Yan R, Dräger N, Leng K, Nalls MA, Singleton AB, Xu K, Faghri F, Kampmann M | Nature neuroscience | 34031600 | Nat Neurosci | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34031600 |
Single Molecules Are Your Quanta: A Bottom-Up Approach toward Multidimensional Super-resolution Microscopy. | Xiang L, Chen K, Xu K | ACS nano | 34304562 | ACS Nano | 2021 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/34304562 |
Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing. | Chen K, Yan R, Xiang L, Xu K | Light, science & applications | 33963178 | Light Sci Appl | 2021 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/33963178 |
SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport. | Yan R, Chen K, Wang B, Xu K | Developmental cell | 35051356 | Dev Cell | 2022 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/35051356 |
Vertebrate cells differentially interpret ciliary and extraciliary cAMP. | Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF | Cell | 33932338 | Cell | 2021 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/33932338 |
Multidimensional Super-Resolution Microscopy Unveils Nanoscale Surface Aggregates in the Aging of FUS Condensates. | He C, Wu CY, Li W, Xu K | Journal of the American Chemical Society | 37782826 | J Am Chem Soc | 2023 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/37782826 |
Displacement Statistics of Unhindered Single Molecules Show no Enhanced Diffusion in Enzymatic Reactions. | Choi AA, Park HH, Chen K, Yan R, Li W, Xu K | Journal of the American Chemical Society | 35258969 | J Am Chem Soc | 2022 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/35258969 |
Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells. | Jin M, Shirazinejad C, Wang B, Yan A, Schöneberg J, Upadhyayula S, Xu K, Drubin DG | Nature communications | 35732852 | Nat Commun | 2022 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/35732852 |
Super-multiplexing excitation spectral microscopy with multiple fluorescence bands. | Chen K, Li W, Xu K | Biomedical optics express | 36733753 | Biomed Opt Express | 2022 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/36733753 |
Graphene-Enabled, Spatially Controlled Electroporation of Adherent Cells for Live-Cell Super-resolution Microscopy. | Moon S, Li W, Hauser M, Xu K | ACS nano | 32282180 | ACS Nano | 2020 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/32282180 |
Single-Molecule Displacement Mapping Indicates Unhindered Intracellular Diffusion of Small (≲1 kDa) Solutes. | Choi AA, Xiang L, Li W, Xu K | Journal of the American Chemical Society | 37027457 | J Am Chem Soc | 2023 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/37027457 |
Carborane Guests for Cucurbit[7]uril Facilitate Strong Binding and On-Demand Removal. | Kataki-Anastasakou A, Axtell JC, Hernandez S, Dziedzic RM, Balaich GJ, Rheingold AL, Spokoyny AM, Sletten EM | Journal of the American Chemical Society | 33253553 | J Am Chem Soc | 2020 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/33253553 |
Cell-surface Labeling via Bioorthogonal Host-Guest Chemistry. | Kataki-Anastasakou A, Hernandez S, Sletten EM | ACS chemical biology | 34669367 | ACS Chem Biol | 2021 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/34669367 |
Bioorthogonal chemistry: Bridging chemistry, biology, and medicine. | Hartung KM, Sletten EM | Chem | 39006002 | Chem | 2023 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/39006002 |
Expanding the Scope of Palladium-Catalyzed B - N Cross-Coupling Chemistry in Carboranes. | Mu X, Hopp M, Dziedzic RM, Waddington MA, Rheingold AL, Sletten EM, Axtell JC, Spokoyny AM | Organometallics | 34012188 | Organometallics | 2020 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/34012188 |
Arene-Perfluoroarene Interactions in Solution. | Lee GY, Hu E, Rheingold AL, Houk KN, Sletten EM | The Journal of organic chemistry | 34077211 | J Org Chem | 2021 Jun 18 | https://www.ncbi.nlm.nih.gov/pubmed/34077211 |
A Fluorescent Unnatural Mannosamine Derivative with Enhanced Emission Upon Complexation with Cucurbit[7]uril. | Kataki-Anastasakou A, Jia S, Axtell JC, Sletten EM | Israel journal of chemistry | 37636996 | Isr J Chem | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/37636996 |
A mixture-density-based tandem optimization network for on-demand inverse design of thin-film high reflectors. | Unni R, Yao K, Han X, Zhou M, Zheng Y | Nanophotonics (Berlin, Germany) | 36425324 | Nanophotonics | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/36425324 |
All-optical reconfigurable chiral meta-molecules. | Lin L, Lepeshov S, Krasnok A, Jiang T, Peng X, Korgel BA, Alù A, Zheng Y | Materials today (Kidlington, England) | 31777449 | Mater Today (Kidlington) | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/31777449 |
Opto-Thermophoretic Manipulation and Construction of Colloidal Superstructures in Photocurable Hydrogels. | Peng X, Li J, Lin L, Liu Y, Zheng Y | ACS applied nano materials | 31106296 | ACS Appl Nano Mater | 2018 Aug 24 | https://www.ncbi.nlm.nih.gov/pubmed/31106296 |
Opto-thermophoretic fiber tweezers. | Kotnala A, Zheng Y | Nanophotonics (Berlin, Germany) | 34290953 | Nanophotonics | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/34290953 |
Optothermally Assembled Nanostructures. | Li J, Zheng Y | Accounts of materials research | 34396151 | Acc Mater Res | 2021 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/34396151 |
Universal optothermal micro/nanoscale rotors. | Ding H, Kollipara PS, Kim Y, Kotnala A, Li J, Chen Z, Zheng Y | Science advances | 35704582 | Sci Adv | 2022 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/35704582 |
Thermo-Electro-Mechanics at Individual Particles in Complex Colloidal Systems. | Kollipara PS, Lin L, Zheng Y | The journal of physical chemistry. C, Nanomaterials and interfaces | 32913480 | J Phys Chem C Nanomater Interfaces | 2019 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/32913480 |
Optical manipulation and assembly of micro/nanoscale objects on solid substrates. | Li J, Alfares A, Zheng Y | iScience | 35313687 | iScience | 2022 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/35313687 |
Room-Temperature Observation of Near-Intrinsic Exciton Linewidth in Monolayer WS(2). | Fang J, Yao K, Zhang T, Wang M, Jiang T, Huang S, Korgel BA, Terrones M, Alù A, Zheng Y | Advanced materials (Deerfield Beach, Fla.) | 35170105 | Adv Mater | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35170105 |
Light-driven C-H activation mediated by 2D transition metal dichalcogenides. | Li J, Zhang D, Guo Z, Chen Z, Jiang X, Larson JM, Zhu H, Zhang T, Gu Y, Blankenship BW, Chen M, Wu Z, Huang S, Kostecki R, Minor AM, Grigoropoulos CP, Akinwande D, Terrones M, Redwing JM, Li H, Zheng Y | Nature communications | 38956055 | Nat Commun | 2024 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/38956055 |
Bubble-pen lithography: Fundamentals and applications: Nanoscience: Special Issue Dedicated to Professor Paul S. Weiss. | Kollipara PS, Mahendra R, Li J, Zheng Y | Aggregate (Hoboken, N.J.) | 37441005 | Aggregate (Hoboken) | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37441005 |
Opto-Thermophoretic Attraction, Trapping, and Dynamic Manipulation of Lipid Vesicles. | Hill EH, Li J, Lin L, Liu Y, Zheng Y | Langmuir : the ACS journal of surfaces and colloids | 30350700 | Langmuir | 2018 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/30350700 |
Opto-thermoelectric nanotweezers. | Lin L, Wang M, Peng X, Lissek EN, Mao Z, Scarabelli L, Adkins E, Coskun S, Unalan HE, Korgel BA, Liz-Marzán LM, Florin EL, Zheng Y | Nature photonics | 29785202 | Nat Photonics | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29785202 |
Optical Nanoprinting of Colloidal Particles and Functional Structures. | Li J, Hill EH, Lin L, Zheng Y | ACS nano | 30875190 | ACS Nano | 2019 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/30875190 |
Optical Patterning of Two-Dimensional Materials. | Kollipara PS, Li J, Zheng Y | Research (Washington, D.C.) | 32043085 | Research (Wash D C) | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32043085 |
Enhancing Surface Capture and Sensing of Proteins with Low-Power Optothermal Bubbles in a Biphasic Liquid. | Kim Y, Ding H, Zheng Y | Nano letters | 32667815 | Nano Lett | 2020 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/32667815 |
Directional light emission by electric and magnetic dipoles near a nanosphere: an analytical approach based on the generalized Mie theory. | Yao K, Zheng Y | Optics letters | 33449012 | Opt Lett | 2021 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/33449012 |
Directional Modulation of Exciton Emission Using Single Dielectric Nanospheres. | Fang J, Wang M, Yao K, Zhang T, Krasnok A, Jiang T, Choi J, Kahn E, Korgel BA, Terrones M, Li X, Alù A, Zheng Y | Advanced materials (Deerfield Beach, Fla.) | 33837615 | Adv Mater | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33837615 |
Heat-Mediated Optical Manipulation. | Chen Z, Li J, Zheng Y | Chemical reviews | 34797041 | Chem Rev | 2022 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/34797041 |
Opto-refrigerative tweezers. | Li J, Chen Z, Liu Y, Kollipara PS, Feng Y, Zhang Z, Zheng Y | Science advances | 34172454 | Sci Adv | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34172454 |
Digital manufacturing of advanced materials: challenges and perspective. | Lin L, Kollipara PS, Zheng Y | Materials today (Kidlington, England) | 32831619 | Mater Today (Kidlington) | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32831619 |
Sensitivity-Enhancing Strategies in Optical Biosensing. | Kim Y, Gonzales J, Zheng Y | Small (Weinheim an der Bergstrasse, Germany) | 33369864 | Small | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33369864 |
Enhancing Single-Molecule Fluorescence Spectroscopy with Simple and Robust Hybrid Nanoapertures. | Kotnala A, Ding H, Zheng Y | ACS photonics | 35445142 | ACS Photonics | 2021 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/35445142 |
Plasmonic Nanotweezers and Nanosensors for Point-of-Care Applications. | Peng X, Kotnala A, Rajeeva BB, Wang M, Yao K, Bhatt N, Penley D, Zheng Y | Advanced optical materials | 34434691 | Adv Opt Mater | 2021 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/34434691 |
Investigating water/oil interfaces with opto-thermophoresis. | Kim Y, Ding H, Zheng Y | Nature communications | 35768421 | Nat Commun | 2022 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/35768421 |
Deep Convolutional Mixture Density Network for Inverse Design of Layered Photonic Structures. | Unni R, Yao K, Zheng Y | ACS photonics | 38031541 | ACS Photonics | 2020 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/38031541 |
Broadband Forward Light Scattering by Architectural Design of Core-Shell Silicon Particles. | De Marco ML, Jiang T, Fang J, Lacomme S, Zheng Y, Baron A, Korgel BA, Barois P, Drisko GL, Aymonier C | Advanced functional materials | 38031546 | Adv Funct Mater | 2021 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/38031546 |
Light-driven C-H activation mediated by 2D transition metal dichalcogenides. | Li J, Zhang D, Guo Z, Jiang X, Larson JM, Zhu H, Zhang T, Gu Y, Blankenship B, Chen M, Wu Z, Huang S, Kostecki R, Minor AM, Grigoropoulos CP, Akinwande D, Terrones M, Redwing JM, Li H, Zheng Y | Research square | 38260621 | Res Sq | 2024 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/38260621 |
Digital Assembly of Colloidal Particles for Nanoscale Manufacturing. | Kotnala A, Zheng Y | Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems | 33041521 | Part Part Syst Charact | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/33041521 |
Label-Free Ultrasensitive Detection of Abnormal Chiral Metabolites in Diabetes. | Liu Y, Wu Z, Kollipara PS, Montellano R, Sharma K, Zheng Y | ACS nano | 33760602 | ACS Nano | 2021 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/33760602 |
Liquid Optothermoelectrics: Fundamentals and Applications. | Chen Z, Kollipara PS, Ding H, Pughazhendi A, Zheng Y | Langmuir : the ACS journal of surfaces and colloids | 33410698 | Langmuir | 2021 Feb 2 | https://www.ncbi.nlm.nih.gov/pubmed/33410698 |
Tunable Chiral Optics in All-Solid-Phase Reconfigurable Dielectric Nanostructures. | Li J, Wang M, Wu Z, Li H, Hu G, Jiang T, Guo J, Liu Y, Yao K, Chen Z, Fang J, Fan D, Korgel BA, Alù A, Zheng Y | Nano letters | 33372805 | Nano Lett | 2021 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/33372805 |
Optothermal Manipulations of Colloidal Particles and Living Cells. | Lin L, Hill EH, Peng X, Zheng Y | Accounts of chemical research | 29799720 | Acc Chem Res | 2018 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/29799720 |
Nanoradiator-Mediated Deterministic Opto-Thermoelectric Manipulation. | Liu Y, Lin L, Bangalore Rajeeva B, Jarrett JW, Li X, Peng X, Kollipara P, Yao K, Akinwande D, Dunn AK, Zheng Y | ACS nano | 30226980 | ACS Nano | 2018 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/30226980 |
Optical nanomanipulation on solid substrates via optothermally-gated photon nudging. | Li J, Liu Y, Lin L, Wang M, Jiang T, Guo J, Ding H, Kollipara PS, Inoue Y, Fan D, Korgel BA, Zheng Y | Nature communications | 31831746 | Nat Commun | 2019 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/31831746 |
Opto-thermoelectric speckle tweezers. | Kotnala A, Kollipara PS, Zheng Y | Nanophotonics (Berlin, Germany) | 34290954 | Nanophotonics | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/34290954 |
Decoding Optical Data with Machine Learning. | Fang J, Swain A, Unni R, Zheng Y | Laser & photonics reviews | 34539925 | Laser Photon Rev | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34539925 |
Tunable Strong Coupling in Transition Metal Dichalcogenide Nanowires. | Li J, Yao K, Huang Y, Fang J, Kollipara PS, Fan DE, Zheng Y | Advanced materials (Deerfield Beach, Fla.) | 35793202 | Adv Mater | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35793202 |
Programmable Multimodal Optothermal Manipulation of Synthetic Particles and Biological Cells. | Ding H, Chen Z, Kollipara PS, Liu Y, Kim Y, Huang S, Zheng Y | ACS nano | 35816157 | ACS Nano | 2022 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/35816157 |
Opto-Thermophoretic Tweezers and Assembly. | Li J, Lin L, Inoue Y, Zheng Y | Journal of micro- and nano-manufacturing | 35832388 | J Micro Nanomanuf | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/35832388 |
Light-driven single-cell rotational adhesion frequency assay. | Liu Y, Ding H, Li J, Lou X, Yang M, Zheng Y | eLight | 35965781 | eLight | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35965781 |
Overcoming Diffusion-Limited Trapping in Nanoaperture Tweezers Using Opto-Thermal-Induced Flow. | Kotnala A, Kollipara PS, Li J, Zheng Y | Nano letters | 31834809 | Nano Lett | 2020 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/31834809 |
Atomistic modeling and rational design of optothermal tweezers for targeted applications. | Ding H, Kollipara PS, Lin L, Zheng Y | Nano research | 35475031 | Nano Res | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/35475031 |
Opto-thermoelectric microswimmers. | Peng X, Chen Z, Kollipara PS, Liu Y, Fang J, Lin L, Zheng Y | Light, science & applications | 32864116 | Light Sci Appl | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32864116 |
Optothermophoretic Manipulation of Colloidal Particles in Nonionic Liquids. | Peng X, Lin L, Hill EH, Kunal P, Humphrey SM, Zheng Y | The journal of physical chemistry. C, Nanomaterials and interfaces | 30766650 | J Phys Chem C Nanomater Interfaces | 2018 Oct 25 | https://www.ncbi.nlm.nih.gov/pubmed/30766650 |
Suppressing material loss in the visible and near-infrared range for functional nanophotonics using bandgap engineering. | Wang M, Krasnok A, Lepeshov S, Hu G, Jiang T, Fang J, Korgel BA, Alù A, Zheng Y | Nature communications | 33028825 | Nat Commun | 2020 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/33028825 |
Controlling the polarization of chiral dipolar emission with a spherical dielectric nanoantenna. | Yao K, Zheng Y | The Journal of chemical physics | 34911301 | J Chem Phys | 2021 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/34911301 |
Opto-Thermocapillary Nanomotors on Solid Substrates. | Li J, Kollipara PS, Liu Y, Yao K, Liu Y, Zheng Y | ACS nano | 35594375 | ACS Nano | 2022 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/35594375 |
Intelligent nanophotonics: merging photonics and artificial intelligence at the nanoscale. | Yao K, Unni R, Zheng Y | Nanophotonics (Berlin, Germany) | 34290952 | Nanophotonics | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/34290952 |
Opto-Thermoelectric Tweezers: Principles and Applications. | Pughazhendi A, Chen Z, Wu Z, Li J, Zheng Y | Frontiers in physics | 38031585 | Front Phys | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/38031585 |
Influenza A virus rapidly adapts particle shape to environmental pressures. | Partlow EA, Jaeggi-Wong A, Planitzer SD, Berg N, Li Z, Ivanovic T | Nature microbiology | 39929974 | Nat Microbiol | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/39929974 |
Hemagglutinin Stability Determines Influenza A Virus Susceptibility to a Broad-Spectrum Fusion Inhibitor Arbidol. | Li Z, Li T, Liu M, Ivanovic T | ACS infectious diseases | 35819162 | ACS Infect Dis | 2022 Aug 12 | https://www.ncbi.nlm.nih.gov/pubmed/35819162 |
The shape of pleomorphic virions determines resistance to cell-entry pressure. | Li T, Li Z, Deans EE, Mittler E, Liu M, Chandran K, Ivanovic T | Nature microbiology | 33737748 | Nat Microbiol | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33737748 |
SCINA: A Semi-Supervised Subtyping Algorithm of Single Cells and Bulk Samples. | Zhang Z, Luo D, Zhong X, Choi JH, Ma Y, Wang S, Mahrt E, Guo W, Stawiski EW, Modrusan Z, Seshagiri S, Kapur P, Hon GC, Brugarolas J, Wang T | Genes | 31336988 | Genes (Basel) | 2019 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/31336988 |
FBA: feature barcoding analysis for single cell RNA-Seq. | Duan J, Hon GC | Bioinformatics (Oxford, England) | 33999185 | Bioinformatics | 2021 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/33999185 |
Breaking enhancers to gain insights into developmental defects. | Armendariz DA, Sundarrajan A, Hon GC | eLife | 37497775 | Elife | 2023 Jul 27 | https://www.ncbi.nlm.nih.gov/pubmed/37497775 |
Frequent sgRNA-barcode recombination in single-cell perturbation assays. | Xie S, Cooley A, Armendariz D, Zhou P, Hon GC | PloS one | 29874289 | PLoS One | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29874289 |
Experimental and Computational Approaches for Single-Cell Enhancer Perturbation Assay. | Xie S, Hon GC | Methods in molecular biology (Clifton, N.J.) | 30758829 | Methods Mol Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30758829 |
Rational Reprogramming of Cellular States by Combinatorial Perturbation. | Duan J, Li B, Bhakta M, Xie S, Zhou P, Munshi NV, Hon GC | Cell reports | 31216470 | Cell Rep | 2019 Jun 18 | https://www.ncbi.nlm.nih.gov/pubmed/31216470 |
A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum. | Zhang Y, Li B, Cananzi S, Han C, Wang LL, Zou Y, Fu YX, Hon GC, Zhang CL | Proceedings of the National Academy of Sciences of the United States of America | 35254903 | Proc Natl Acad Sci U S A | 2022 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/35254903 |
Computational identification of clonal cells in single-cell CRISPR screens. | Wang Y, Xie S, Armendariz D, Hon GC | BMC genomics | 35168568 | BMC Genomics | 2022 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/35168568 |
CHD-associated enhancers shape human cardiomyocyte lineage commitment. | Armendariz DA, Goetsch SC, Sundarrajan A, Sivakumar S, Wang Y, Xie S, Munshi NV, Hon GC | eLife | 37096669 | Elife | 2023 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/37096669 |
Benchmarking and optimizing Perturb-seq in differentiating human pluripotent stem cells. | Sivakumar S, Wang Y, Goetsch SC, Pandit V, Wang L, Zhao H, Sundarrajan A, Armendariz D, Takeuchi C, Nzima M, Chen WC, Dederich AE, El Hayek L, Gao T, Ghazawi R, Gogate A, Kaur K, Kim HB, McCoy MK, Niederstrasser H, Oura S, Pinzon-Arteaga CA, Sanghvi M, Schmitz DA, Yu L, Zhang Y, Zhou Q, Kraus WL, Xu L, Wu J, Posner BA, Chahrour MH, Hon GC, Munshi NV | bioRxiv : the preprint server for biology | 39896670 | bioRxiv | 2025 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/39896670 |
Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice. | Hepler C, Shan B, Zhang Q, Henry GH, Shao M, Vishvanath L, Ghaben AL, Mobley AB, Strand D, Hon GC, Gupta RK | eLife | 30265241 | Elife | 2018 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/30265241 |
Single-Cell Genomics: Catalyst for Cell Fate Engineering. | Li B, Hon GC | Frontiers in bioengineering and biotechnology | 34733831 | Front Bioeng Biotechnol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34733831 |
Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption. | Cooley A, Madhukaran S, Stroebele E, Colon Caraballo M, Wang L, Akgul Y, Hon GC, Mahendroo M | iScience | 36718364 | iScience | 2023 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/36718364 |
Global Analysis of Enhancer Targets Reveals Convergent Enhancer-Driven Regulatory Modules. | Xie S, Armendariz D, Zhou P, Duan J, Hon GC | Cell reports | 31775028 | Cell Rep | 2019 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/31775028 |
A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra. | Henry GH, Malewska A, Joseph DB, Malladi VS, Lee J, Torrealba J, Mauck RJ, Gahan JC, Raj GV, Roehrborn CG, Hon GC, MacConmara MP, Reese JC, Hutchinson RC, Vezina CM, Strand DW | Cell reports | 30566875 | Cell Rep | 2018 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/30566875 |
Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition. | Bhattacharyya S, Duan J, Wang L, Li B, Bhakta M, Fernandez-Perez A, Hon GC, Munshi NV | Scientific reports | 30765799 | Sci Rep | 2019 Feb 14 | https://www.ncbi.nlm.nih.gov/pubmed/30765799 |
Enhancer regulatory networks globally connect non-coding breast cancer loci to cancer genes. | Wang Y, Armendariz D, Wang L, Zhao H, Xie S, Hon GC | bioRxiv : the preprint server for biology | 38045327 | bioRxiv | 2023 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/38045327 |
Accurate Classification of Cardiomyopathy Diagnosis by Chromatin Accessibility. | Bhattacharyya S, Duan J, Vela RJ, Bhakta M, Bajona P, Mammen PPA, Hon GC, Munshi NV | Circulation | 36095061 | Circulation | 2022 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/36095061 |
Hormonal modulation of reproduction in Polistes fuscatus social wasps: Dual functions in both ovary development and sexual receptivity. | Walton A, Tumulty JP, Toth AL, Sheehan MJ | Journal of insect physiology | 31705844 | J Insect Physiol | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31705844 |
Expansion and Accelerated Evolution of 9-Exon Odorant Receptors in Polistes Paper Wasps. | Legan AW, Jernigan CM, Miller SE, Fuchs MF, Sheehan MJ | Molecular biology and evolution | 34151983 | Mol Biol Evol | 2021 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/34151983 |
Coevolution of cognitive abilities and identity signals in individual recognition systems. | Miller SE, Sheehan MJ, Reeve HK | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 32420843 | Philos Trans R Soc Lond B Biol Sci | 2020 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/32420843 |
Evidence for a selective link between cooperation and individual recognition. | Tumulty JP, Miller SE, Van Belleghem SM, Weller HI, Jernigan CM, Vincent S, Staudenraus RJ, Legan AW, Polnaszek TJ, Uy FMK, Walton A, Sheehan MJ | Current biology : CB | 38065097 | Curr Biol | 2023 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/38065097 |
Postural analysis reveals persistent changes in paper wasp foundress behavioral state after conspecific challenge. | Legan AW, Vogt CC, Sheehan MJ | Ecology and evolution | 37664514 | Ecol Evol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37664514 |
Distinct evolutionary trajectories of V1R clades across mouse species. | Miller CH, Campbell P, Sheehan MJ | BMC evolutionary biology | 32770934 | BMC Evol Biol | 2020 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/32770934 |
Strong, but incomplete, mate choice discrimination between two closely related species of paper wasp. | Miller SE, Legan AW, Flores ZA, Ng HY, Sheehan MJ | Biological journal of the Linnean Society. Linnean Society of London | 30853716 | Biol J Linn Soc Lond | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30853716 |
Age and social experience induced plasticity across brain regions of the paper wasp Polistes fuscatus. | Jernigan CM, Zaba NC, Sheehan MJ | Biology letters | 33849349 | Biol Lett | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33849349 |
The promises and challenges of archiving insect behavior and natural history in a changing world. | Sheehan MJ, Miller SE | Current opinion in insect science | 33857642 | Curr Opin Insect Sci | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33857642 |
WASPnest: a worldwide assessment of social Polistine nesting behavior. | Miller SE, Bluher SE, Bell E, Cini A, Silva RCD, de Souza AR, Gandia KM, Jandt J, Loope K, Prato A, Pruitt JN, Rankin D, Rankin E, Southon RJ, Uy FMK, Weiner S, Wright CM, Downing H, Gadagkar R, Cristina Lorenzi M, Rusina L, Sumner S, Tibbetts EA, Toth A, Sheehan MJ | Ecology | 29999519 | Ecology | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29999519 |
Animal Behavior: Socially Distanced Wasps Learn About Rivals. | Sheehan MJ, Goldberg J | Current biology : CB | 32750347 | Curr Biol | 2020 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/32750347 |
Rapid local adaptation linked with phenotypic plasticity. | Sun SJ, Catherall AM, Pascoal S, Jarrett BJM, Miller SE, Sheehan MJ, Kilner RM | Evolution letters | 32774883 | Evol Lett | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32774883 |
Evolutionary dynamics of recent selection on cognitive abilities. | Miller SE, Legan AW, Henshaw MT, Ostevik KL, Samuk K, Uy FMK, Sheehan MJ | Proceedings of the National Academy of Sciences of the United States of America | 31980529 | Proc Natl Acad Sci U S A | 2020 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/31980529 |
Dynamic neurogenomic responses to social interactions and dominance outcomes in female paper wasps. | Uy FMK, Jernigan CM, Zaba NC, Mehrotra E, Miller SE, Sheehan MJ | PLoS genetics | 34478434 | PLoS Genet | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34478434 |
Highly Contiguous Genome Assemblies of the Guinea Paper Wasp (Polistes exclamans) and Mischocyttarus mexicanus. | Miller SE, Legan AW, Uy FMK, Sheehan MJ | Genome biology and evolution | 35880292 | Genome Biol Evol | 2022 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/35880292 |
Evolutionarily stable investments in recognition systems explain patterns of discrimination failure and success. | Sheehan MJ, Reeve HK | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 32420853 | Philos Trans R Soc Lond B Biol Sci | 2020 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/32420853 |
Fine-Scale Population Structure but Limited Genetic Differentiation in a Cooperatively Breeding Paper Wasp. | Bluher SE, Miller SE, Sheehan MJ | Genome biology and evolution | 32271866 | Genome Biol Evol | 2020 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/32271866 |
Color is necessary for face discrimination in the Northern paper wasp, Polistes fuscatus. | Jernigan CM, Stafstrom JA, Zaba NC, Vogt CC, Sheehan MJ | Animal cognition | 36245014 | Anim Cogn | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36245014 |
Sex differences in deleterious genetic variants in a haplodiploid social insect. | Miller SE, Sheehan MJ | Molecular ecology | 37350360 | Mol Ecol | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37350360 |
Detergent headgroups control TolC folding in vitro. | Ikujuni AP, Budiardjo SJ, Dhar R, Slusky JSG | Biophysical journal | 36772796 | Biophys J | 2023 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/36772796 |
Efflux Pumps Represent Possible Evolutionary Convergence onto the β-Barrel Fold. | Franklin MW, Nepomnyachiy S, Feehan R, Ben-Tal N, Kolodny R, Slusky JSG | Structure (London, England : 1993) | 30057025 | Structure | 2018 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/30057025 |
Evolutionary Engineering a Larger Porin Using a Loop-to-Hairpin Mechanism. | Dhar R, Bowman AM, Hatungimana B, Sg Slusky J | Journal of molecular biology | 37769963 | J Mol Biol | 2023 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/37769963 |
Evolutionary engineering a larger porin using a loop-to-hairpin mechanism. | Dhar R, Bowman AM, Hatungimana B, Slusky JS | bioRxiv : the preprint server for biology | 37398247 | bioRxiv | 2023 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/37398247 |
MAHOMES II: A webserver for predicting if a metal binding site is enzymatic. | Feehan R, Copeland M, Franklin MW, Slusky JSG | Protein science : a publication of the Protein Society | 36916762 | Protein Sci | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36916762 |
High-Yield Preparation of Outer Membrane Protein Efflux Pumps by in Vitro Refolding is Concentration Dependent. | Budiardjo SJ, Ikujuni AP, Firlar E, Cordova A, Kaelber JT, Slusky JSG | The Journal of membrane biology | 33462665 | J Membr Biol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33462665 |
Machine learning differentiates enzymatic and non-enzymatic metals in proteins. | Feehan R, Franklin MW, Slusky JSG | Nature communications | 34140507 | Nat Commun | 2021 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/34140507 |
MAHOMES II: A webserver for predicting if a metal binding site is enzymatic. | Feehan R, Copeland M, Franklin MW, Slusky JSG | bioRxiv : the preprint server for biology | 36945603 | bioRxiv | 2023 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/36945603 |
Tight Turns of Outer Membrane Proteins: An Analysis of Sequence, Structure, and Hydrogen Bonding. | Franklin MW, Slusky JSG | Journal of molecular biology | 29944853 | J Mol Biol | 2018 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/29944853 |
Evolutionary pathways of repeat protein topology in bacterial outer membrane proteins. | Franklin MW, Nepomnyachyi S, Feehan R, Ben-Tal N, Kolodny R, Slusky JS | eLife | 30489257 | Elife | 2018 Nov 29 | https://www.ncbi.nlm.nih.gov/pubmed/30489257 |
Machine learning for enzyme engineering, selection and design. | Feehan R, Montezano D, Slusky JSG | Protein engineering, design & selection : PEDS | 34296736 | Protein Eng Des Sel | 2021 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/34296736 |
General features of transmembrane beta barrels from a large database. | Montezano D, Bernstein R, Copeland MM, Slusky JSG | Proceedings of the National Academy of Sciences of the United States of America | 37432995 | Proc Natl Acad Sci U S A | 2023 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/37432995 |
Membrane Barrels Are Taller, Fatter, Inside-Out Soluble Barrels. | Dhar R, Feehan R, Slusky JSG | The journal of physical chemistry. B | 33797916 | J Phys Chem B | 2021 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/33797916 |
Colicin E1 opens its hinge to plug TolC. | Budiardjo SJ, Stevens JJ, Calkins AL, Ikujuni AP, Wimalasena VK, Firlar E, Case DA, Biteen JS, Kaelber JT, Slusky JSG | eLife | 35199644 | Elife | 2022 Feb 24 | https://www.ncbi.nlm.nih.gov/pubmed/35199644 |
Outer membrane protein evolution. | Dhar R, Slusky JS | Current opinion in structural biology | 33493965 | Curr Opin Struct Biol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33493965 |
Discovery and Characterization of Two Folded Intermediates for Outer Membrane Protein TolC Biogenesis. | Ikujuni AP, Dhar R, Cordova A, Bowman AM, Noga S, Slusky JSG | Journal of molecular biology | 38871177 | J Mol Biol | 2024 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/38871177 |
Observation of conformational dynamics in single light-harvesting proteins from cryptophyte algae. | Moya R, Norris AC, Spangler LC, Scholes GD, Schlau-Cohen GS | The Journal of chemical physics | 35868944 | J Chem Phys | 2022 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/35868944 |
Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor. | Gordon JB, Hoffman MC, Troiano JM, Li M, Hazelbauer GL, Schlau-Cohen GS | ACS chemical biology | 34647725 | ACS Chem Biol | 2021 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/34647725 |
Ligand-induced transmembrane conformational coupling in monomeric EGFR. | Srinivasan S, Regmi R, Lin X, Dreyer CA, Chen X, Quinn SD, He W, Coleman MA, Carraway KL 3rd, Zhang B, Schlau-Cohen GS | Nature communications | 35794108 | Nat Commun | 2022 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/35794108 |
Phosphorylation-Dependent Conformations of the Disordered Carboxyl-Terminus Domain in the Epidermal Growth Factor Receptor. | Regmi R, Srinivasan S, Latham AP, Kukshal V, Cui W, Zhang B, Bose R, Schlau-Cohen GS | The journal of physical chemistry letters | 33179922 | J Phys Chem Lett | 2020 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/33179922 |
Nanoscale 3D spatial addressing and valence control of quantum dots using wireframe DNA origami. | Chen C, Wei X, Parsons MF, Guo J, Banal JL, Zhao Y, Scott MN, Schlau-Cohen GS, Hernandez R, Bathe M | Nature communications | 35999227 | Nat Commun | 2022 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/35999227 |
Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single-molecule pump-probe spectroscopy. | Moya R, Norris AC, Kondo T, Schlau-Cohen GS | Nature chemistry | 34992285 | Nat Chem | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34992285 |
Tuning Optical Absorption and Emission Using Strongly Coupled Dimers in Programmable DNA Scaffolds. | Hart SM, Wang X, Guo J, Bathe M, Schlau-Cohen GS | The journal of physical chemistry letters | 35175058 | J Phys Chem Lett | 2022 Feb 24 | https://www.ncbi.nlm.nih.gov/pubmed/35175058 |
Spectrally-tunable femtosecond single-molecule pump-probe spectroscopy. | Moya R, Kondo T, Norris AC, Schlau-Cohen GS | Optics express | 34614960 | Opt Express | 2021 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/34614960 |
Evolving artificial metalloenzymes via random mutagenesis. | Yang H, Swartz AM, Park HJ, Srivastava P, Ellis-Guardiola K, Upp DM, Lee G, Belsare K, Gu Y, Zhang C, Moellering RE, Lewis JC | Nature chemistry | 29461523 | Nat Chem | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29461523 |
Chemical probes for spatially resolved measurement of active enzymes in single cells. | Li G, Moellering RE | Methods in enzymology | 31668232 | Methods Enzymol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31668232 |
Versatile Peptide Macrocyclization with Diels-Alder Cycloadditions. | Montgomery JE, Donnelly JA, Fanning SW, Speltz TE, Shangguan X, Coukos JS, Greene GL, Moellering RE | Journal of the American Chemical Society | 31523967 | J Am Chem Soc | 2019 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/31523967 |
Diels-Alder Cycloadditions for Peptide Macrocycle Formation. | Montgomery JE, Moellering RE | Methods in molecular biology (Clifton, N.J.) | 34596848 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/34596848 |
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. | Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaženović I, Lastra RR, Curtis M, Yamada SD, Perets R, McGregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel E | Nature | 31043742 | Nature | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/31043742 |
High throughput discovery of functional protein modifications by Hotspot Thermal Profiling. | Huang JX, Lee G, Cavanaugh KE, Chang JW, Gardel ML, Moellering RE | Nature methods | 31384043 | Nat Methods | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31384043 |
Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains. | Speltz TE, Qiao Z, Swenson CS, Shangguan X, Coukos JS, Lee CW, Thomas DM, Santana J, Fanning SW, Greene GL, Moellering RE | Nature biotechnology | 36302987 | Nat Biotechnol | 2023 Apr | https://www.ncbi.nlm.nih.gov/pubmed/36302987 |
Photoproximity Profiling of Protein-Protein Interactions in Cells. | McCutcheon DC, Lee G, Carlos A, Montgomery JE, Moellering RE | Journal of the American Chemical Society | 31820968 | J Am Chem Soc | 2020 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/31820968 |
Chemoproteomic Profiling of Phosphoaspartate Modifications in Prokaryotes. | Chang JW, Montgomery JE, Lee G, Moellering RE | Angewandte Chemie (International ed. in English) | 30231186 | Angew Chem Int Ed Engl | 2018 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/30231186 |
Family-Wide Photoproximity Profiling of Integrin Protein Social Networks in Cancer. | Carlos AJ, Yang D, Thomas DM, Huang S, Harter KI, Moellering RE | bioRxiv : the preprint server for biology | 39345550 | bioRxiv | 2024 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/39345550 |
A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. | Bollong MJ, Lee G, Coukos JS, Yun H, Zambaldo C, Chang JW, Chin EN, Ahmad I, Chatterjee AK, Lairson LL, Schultz PG, Moellering RE | Nature | 30323285 | Nature | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30323285 |
Ultrasensitive, multiplexed chemoproteomic profiling with soluble activity-dependent proximity ligation. | Li G, Eckert MA, Chang JW, Montgomery JE, Chryplewicz A, Lengyel E, Moellering RE | Proceedings of the National Academy of Sciences of the United States of America | 31591248 | Proc Natl Acad Sci U S A | 2019 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/31591248 |
A Concise, Modular Antibody-Oligonucleotide Conjugation Strategy Based on Disuccinimidyl Ester Activation Chemistry. | Li G, Moellering RE | Chembiochem : a European journal of chemical biology | 30767357 | Chembiochem | 2019 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/30767357 |
An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells. | Li G, Montgomery JE, Eckert MA, Chang JW, Tienda SM, Lengyel E, Moellering RE | Nature communications | 29176560 | Nat Commun | 2017 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/29176560 |
Label-Free Vibrational and Quantitative Phase Microscopy Reveals Remarkable Pathogen-Induced Morphomolecular Divergence in Tumor-Derived Cells. | Liu Z, Parida S, Wu S, Sears CL, Sharma D, Barman I | ACS sensors | 35583030 | ACS Sens | 2022 May 27 | https://www.ncbi.nlm.nih.gov/pubmed/35583030 |
Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment. | Paidi SK, Diaz PM, Dadgar S, Jenkins SV, Quick CM, Griffin RJ, Dings RPM, Rajaram N, Barman I | Cancer research | 30819665 | Cancer Res | 2019 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/30819665 |
Ultrasensitive Detection of Hepatotoxic Microcystin Production from Cyanobacteria Using Surface-Enhanced Raman Scattering Immunosensor. | Li M, Paidi SK, Sakowski E, Preheim S, Barman I | ACS sensors | 30990314 | ACS Sens | 2019 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/30990314 |
Reagent-Free and Rapid Assessment of T Cell Activation State Using Diffraction Phase Microscopy and Deep Learning. | Karandikar SH, Zhang C, Meiyappan A, Barman I, Finck C, Srivastava PK, Pandey R | Analytical chemistry | 30741527 | Anal Chem | 2019 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/30741527 |
Self-Folding Hybrid Graphene Skin for 3D Biosensing. | Xu W, Paidi SK, Qin Z, Huang Q, Yu CH, Pagaduan JV, Buehler MJ, Barman I, Gracias DH | Nano letters | 30433789 | Nano Lett | 2019 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/30433789 |
Mapping the genetic basis of breast microcalcifications and their role in metastasis. | Rizwan A, Paidi SK, Zheng C, Cheng M, Barman I, Glunde K | Scientific reports | 30038419 | Sci Rep | 2018 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/30038419 |
Decoding Live Cell Interactions with Multi-Nanoparticle Systems: Differential Implications for Uptake, Trafficking, and Gene Regulation. | Liang L, Liu Z, Barman I | ACS applied materials & interfaces | 31436085 | ACS Appl Mater Interfaces | 2019 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/31436085 |
Shedding Light on the Trehalose-Enabled Mucopermeation of Nanoparticles with Label-Free Raman Spectroscopy. | Siddhanta S, Bhattacharjee S, Harrison SM, Scholz D, Barman I | Small (Weinheim an der Bergstrasse, Germany) | 31267720 | Small | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31267720 |
Optical properties of symmetry-breaking tetrahedral nanoparticles. | Zheng P , Paria D , Wang H , Li M , Barman I | Nanoscale | 31830188 | Nanoscale | 2020 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/31830188 |
Rapid, Label-free Optical Spectroscopy Platform for Diagnosis of Heparin-Induced Thrombocytopenia. | Huang Z, Siddhanta S, Zheng G, Kickler T, Barman I | Angewandte Chemie (International ed. in English) | 31972060 | Angew Chem Int Ed Engl | 2020 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/31972060 |
Label-free spectrochemical probe for determination of hemoglobin glycation in clinical blood samples. | Pandey R, Singh SP, Zhang C, Horowitz GL, Lue N, Galindo L, Dasari RR, Barman I | Journal of biophotonics | 29726123 | J Biophotonics | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29726123 |
Pyramidal hyperbolic metasurfaces enhance spontaneous emission of nitrogen-vacancy centers in nanodiamond. | Zheng P, Liang L, Arora S, Ray K, Semancik S, Barman I | Advanced optical materials | 37920689 | Adv Opt Mater | 2023 Mar 17 | https://www.ncbi.nlm.nih.gov/pubmed/37920689 |
Coarse Raman and optical diffraction tomographic imaging enable label-free phenotyping of isogenic breast cancer cells of varying metastatic potential. | Paidi SK, Shah V, Raj P, Glunde K, Pandey R, Barman I | Biosensors & bioelectronics | 33272866 | Biosens Bioelectron | 2021 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/33272866 |
Towards rational design and optimization of near-field enhancement and spectral tunability of hybrid core-shell plasmonic nanoprobes. | Paria D, Zhang C, Barman I | Scientific reports | 31690763 | Sci Rep | 2019 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/31690763 |
A Programmable DNA-Silicification-Based Nanocavity for Single-Molecule Plasmonic Sensing. | Liang L, Zheng P, Zhang C, Barman I | Advanced materials (Deerfield Beach, Fla.) | 33458901 | Adv Mater | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33458901 |
Furin-Mediated Self-Assembly of Olsalazine Nanoparticles for Targeted Raman Imaging of Tumors. | Yuan Y, Raj P, Zhang J, Siddhanta S, Barman I, Bulte JWM | Angewandte Chemie (International ed. in English) | 33325142 | Angew Chem Int Ed Engl | 2021 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/33325142 |
Silver-Coated Disordered Silicon Nanowires Provide Highly Sensitive Label-Free Glycated Albumin Detection through Molecular Trapping and Plasmonic Hotspot Formation. | Paria D, Convertino A, Mussi V, Maiolo L, Barman I | Advanced healthcare materials | 33236490 | Adv Healthc Mater | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33236490 |
Identification and Staging of B-Cell Acute Lymphoblastic Leukemia Using Quantitative Phase Imaging and Machine Learning. | Ayyappan V, Chang A, Zhang C, Paidi SK, Bordett R, Liang T, Barman I, Pandey R | ACS sensors | 33092347 | ACS Sens | 2020 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/33092347 |
A Dual-Modal Single-Antibody Plasmonic Spectro-Immunoassay for Detection of Small Molecules. | Zheng P, Wu L, Raj P, Mizutani T, Szabo M, Hanson WA, Barman I | Small (Weinheim an der Bergstrasse, Germany) | 35373504 | Small | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35373504 |
Label-Free Morpho-Molecular Imaging for Studying the Differential Interaction of Black Phosphorus with Tumor Cells. | Mussi V, Fasolino I, Paria D, De Simone S, Caporali M, Serrano-Ruiz M, Ambrosio L, Barman I, Raucci MG, Convertino A | Nanomaterials (Basel, Switzerland) | 35745333 | Nanomaterials (Basel) | 2022 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/35745333 |
RaMALDI: Enabling simultaneous Raman and MALDI imaging of the same tissue section. | Yang E, Kim JH, Tressler CM, Shen XE, Brown DR, Johnson CC, Hahm TH, Barman I, Glunde K | Biosensors & bioelectronics | 37597501 | Biosens Bioelectron | 2023 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/37597501 |
Quantitative Detection of Thyroid-Stimulating Hormone in Patient Samples with a Nanomechanical Single-Antibody Spectro-Immunoassay. | Zheng P, Raj P, Wu L, Mizutani T, Szabo M, Hanson WA, Barman I | Small (Weinheim an der Bergstrasse, Germany) | 37752776 | Small | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/37752776 |
Molecular Radiative Energy Shifts under Strong Oscillating Fields. | Zheng P, Kang J, Paria D, Kang JU, Barman I | Small (Weinheim an der Bergstrasse, Germany) | 33354911 | Small | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33354911 |
Integration of diffraction phase microscopy and Raman imaging for label-free morpho-molecular assessment of live cells. | Pandey R, Zhou R, Bordett R, Hunter C, Glunde K, Barman I, Valdez T, Finck C | Journal of biophotonics | 30421505 | J Biophotonics | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30421505 |
Composite-Scattering Plasmonic Nanoprobes for Label-Free, Quantitative Biomolecular Sensing. | Zhang C, Paria D, Semancik S, Barman I | Small (Weinheim an der Bergstrasse, Germany) | 31394029 | Small | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31394029 |
Optical diffraction tomography and Raman spectroscopy reveal distinct cellular phenotypes during white and brown adipocyte differentiation. | Anantha P, Liu Z, Raj P, Barman I | Biosensors & bioelectronics | 37207582 | Biosens Bioelectron | 2023 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/37207582 |
Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy. | Paidi SK, Rodriguez Troncoso J, Raj P, Monterroso Diaz P, Ivers JD, Lee DE, Avaritt NL, Gies AJ, Quick CM, Byrum SD, Tackett AJ, Rajaram N, Barman I | Cancer research | 34645610 | Cancer Res | 2021 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/34645610 |
Raman and quantitative phase imaging allow morpho-molecular recognition of malignancy and stages of B-cell acute lymphoblastic leukemia. | Paidi SK, Raj P, Bordett R, Zhang C, Karandikar SH, Pandey R, Barman I | Biosensors & bioelectronics | 34130086 | Biosens Bioelectron | 2021 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/34130086 |
Vibrational spectroscopy for decoding cancer microbiota interactions: Current evidence and future perspective. | Liu Z, Parida S, Prasad R, Pandey R, Sharma D, Barman I | Seminars in cancer biology | 34273519 | Semin Cancer Biol | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34273519 |
Raman spectroscopy reveals phenotype switches in breast cancer metastasis. | Paidi SK, Troncoso JR, Harper MG, Liu Z, Nguyen KG, Ravindranathan S, Rebello L, Lee DE, Ivers JD, Zaharoff DA, Rajaram N, Barman I | Theranostics | 35910801 | Theranostics | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35910801 |
Hyperspectral Raman Imaging for Automated Recognition of Human Renal Amyloid. | Kim JH, Zhang C, Sperati CJ, Barman I, Bagnasco SM | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society | 37833851 | J Histochem Cytochem | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37833851 |
Non-Perturbative Identification and Subtyping of Amyloidosis in Human Kidney Tissue with Raman Spectroscopy and Machine Learning. | Kim JH, Zhang C, Sperati CJ, Bagnasco SM, Barman I | Biosensors | 37185541 | Biosensors (Basel) | 2023 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/37185541 |
Rapid, quantitative determination of aggregation and particle formation for antibody drug conjugate therapeutics with label-free Raman spectroscopy. | Zhang C, Springall JS, Wang X, Barman I | Analytica chimica acta | 31446951 | Anal Chim Acta | 2019 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/31446951 |
Cancer cells display increased migration and deformability in pace with metastatic progression. | Liu Z, Lee SJ, Park S, Konstantopoulos K, Glunde K, Chen Y, Barman I | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 32463148 | FASEB J | 2020 Jul | https://www.ncbi.nlm.nih.gov/pubmed/32463148 |
Surface-enhanced Raman scattering: An emerging tool for sensing cellular function. | Tanwar S, Kim JH, Bulte JWM, Barman I | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 35510405 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35510405 |
Label-Free Spectroscopic SARS-CoV-2 Detection on Versatile Nanoimprinted Substrates. | Paria D, Kwok KS, Raj P, Zheng P, Gracias DH, Barman I | Nano letters | 35348344 | Nano Lett | 2022 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/35348344 |
Spectroscopy-Assisted Label-free Molecular Analysis of Live Cell Surface with Vertically Aligned Plasmonic Nanopillars. | Zhang C, Siddhanta S, Paria D, Li Y, Zheng C, Barman I | Small (Weinheim an der Bergstrasse, Germany) | 33942486 | Small | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33942486 |
Plexcitonic Quasi-Bound States in the Continuum. | Zheng P, Raj P, Mizutani T, Szabo M, Hanson WA, Barman I | Small (Weinheim an der Bergstrasse, Germany) | 34411423 | Small | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/34411423 |
Nanowire Assisted Mechanotyping of Cellular Metastatic Potential. | Paria D, Convertino A, Raj P, Glunde K, Chen Y, Barman I | Advanced functional materials | 34512229 | Adv Funct Mater | 2021 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/34512229 |
A Fluorescence and Surface-Enhanced Raman Spectroscopic Dual-Modal Aptasensor for Sensitive Detection of Cyanotoxins. | Li M, Lin H, Paidi SK, Mesyngier N, Preheim S, Barman I | ACS sensors | 32314582 | ACS Sens | 2020 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/32314582 |
Leveraging Nanomechanical Perturbations in Raman Spectro-Immunoassays to Design a Versatile Serum Biomarker Detection Platform. | Zheng P, Raj P, Wu L, Szabo M, Hanson WA, Mizutani T, Barman I | Small (Weinheim an der Bergstrasse, Germany) | 36117050 | Small | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36117050 |
Targeted Enzyme Activity Imaging with Quantitative Phase Microscopy. | Tanwar S, Wu L, Zahn N, Raj P, Ghaemi B, Chatterjee A, Bulte JWM, Barman I | Nano letters | 37154678 | Nano Lett | 2023 May 24 | https://www.ncbi.nlm.nih.gov/pubmed/37154678 |
Engineering vascularized skin-mimetic phantom for non-invasive Raman spectroscopy. | Raj P, Wu L, Arora S, Bhatt R, Zuo Y, Fang Z, Verdoold R, Koch T, Gu L, Barman I | Sensors and actuators. B, Chemical | 38524639 | Sens Actuators B Chem | 2024 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/38524639 |
A Smart Intracellular Self-Assembling Bioorthogonal Raman Active Nanoprobe for Targeted Tumor Imaging. | Tanwar S, Ghaemi B, Raj P, Singh A, Wu L, Yuan Y, Arifin DR, McMahon MT, Bulte JWM, Barman I | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 37715297 | Adv Sci (Weinh) | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37715297 |
Noninvasive morpho-molecular imaging reveals early therapy-induced senescence in human cancer cells. | Bresci A, Kim JH, Ghislanzoni S, Manetti F, Wu L, Vernuccio F, Ceconello C, Sorrentino S, Barman I, Bongarzone I, Cerullo G, Vanna R, Polli D | Science advances | 37703362 | Sci Adv | 2023 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/37703362 |
RNA Localization in Bacteria. | Fei J, Sharma CM | Microbiology spectrum | 30191804 | Microbiol Spectr | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30191804 |
Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells. | Park S, Prévost K, Heideman EM, Carrier MC, Azam MS, Reyer MA, Liu W, Massé E, Fei J | eLife | 33616037 | Elife | 2021 Feb 22 | https://www.ncbi.nlm.nih.gov/pubmed/33616037 |
Mechanical expansion microscopy. | Fan Y, Lim Y, Wyss LS, Park S, Xu C, Fu H, Fei J, Hong Y, Wang B | Methods in cell biology | 33478686 | Methods Cell Biol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33478686 |
RNA molecules display distinctive organization at nuclear speckles. | Paul S, Arias MA, Wen L, Liao SE, Zhang J, Wang X, Regev O, Fei J | iScience | 38638569 | iScience | 2024 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/38638569 |
Deoxyribozyme-based method for absolute quantification of N(6)-methyladenosine fractions at specific sites of RNA. | Bujnowska M, Zhang J, Dai Q, Heideman EM, Fei J | The Journal of biological chemistry | 32269077 | J Biol Chem | 2020 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/32269077 |
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices. | Lerner E, Barth A, Hendrix J, Ambrose B, Birkedal V, Blanchard SC, Börner R, Sung Chung H, Cordes T, Craggs TD, Deniz AA, Diao J, Fei J, Gonzalez RL, Gopich IV, Ha T, Hanke CA, Haran G, Hatzakis NS, Hohng S, Hong SC, Hugel T, Ingargiola A, Joo C, Kapanidis AN, Kim HD, Laurence T, Lee NK, Lee TH, Lemke EA, Margeat E, Michaelis J, Michalet X, Myong S, Nettels D, Peulen TO, Ploetz E, Razvag Y, Robb NC, Schuler B, Soleimaninejad H, Tang C, Vafabakhsh R, Lamb DC, Seidel CA, Weiss S | eLife | 33779550 | Elife | 2021 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/33779550 |
An Improved Method for Bacterial Immunofluorescence Staining To Eliminate Antibody Exclusion from the Fixed Nucleoid. | Park S, Reyer MA, McLean EL, Liu W, Fei J | Biochemistry | 31657208 | Biochemistry | 2019 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/31657208 |
Continuous active development of super-resolution fluorescence microscopy. | Wang Y, Fei J | Physical biology | 32066124 | Phys Biol | 2020 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/32066124 |
Translational T-box riboswitches bind tRNA by modulating conformational flexibility. | Campos-Chavez E, Paul S, Zhou Z, Alonso D, Verma AR, Fei J, Mondragón A | Nature communications | 39097611 | Nat Commun | 2024 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/39097611 |
Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency. | Wu J, Xiao Y, Liu Y, Wen L, Jin C, Liu S, Paul S, He C, Regev O, Fei J | Science advances | 39413186 | Sci Adv | 2024 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/39413186 |
Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA regulators. | Reyer MA, Chennakesavalu S, Heideman EM, Ma X, Bujnowska M, Hong L, Dinner AR, Vanderpool CK, Fei J | Cell reports | 34592145 | Cell Rep | 2021 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/34592145 |
Trophoblast organoids with physiological polarity model placental structure and function. | Yang L, Liang P, Yang H, Coyne CB | bioRxiv : the preprint server for biology | 36711688 | bioRxiv | 2023 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/36711688 |
Molecular basis of PIP(2)-dependent regulation of the Ca(2+)-activated chloride channel TMEM16A. | Le SC, Jia Z, Chen J, Yang H | Nature communications | 31434906 | Nat Commun | 2019 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/31434906 |
An inner activation gate controls TMEM16F phospholipid scrambling. | Le T, Jia Z, Le SC, Zhang Y, Chen J, Yang H | Nature communications | 31015464 | Nat Commun | 2019 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/31015464 |
Conformational plasticity in the selectivity filter of the TRPV2 ion channel. | Zubcevic L, Le S, Yang H, Lee SY | Nature structural & molecular biology | 29728656 | Nat Struct Mol Biol | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29728656 |
Niclosamide potentiates TMEM16A and induces vasoconstriction. | Liang P, Wan YCS, Yu K, Hartzell HC, Yang H | bioRxiv : the preprint server for biology | 37577682 | bioRxiv | 2023 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/37577682 |
Endothelial TMEM16F lipid scramblase regulates angiogenesis. | Shan KZ, Le T, Liang P, Dong P, Yang H | bioRxiv : the preprint server for biology | 37645870 | bioRxiv | 2023 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/37645870 |
Trophoblast organoids with physiological polarity model placental structure and function. | Yang L, Liang P, Yang H, Coyne CB | Journal of cell science | 37676312 | J Cell Sci | 2024 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/37676312 |
Niclosamide potentiates TMEM16A and induces vasoconstriction. | Liang P, Wan YCS, Yu K, Hartzell HC, Yang H | The Journal of general physiology | 38814250 | J Gen Physiol | 2024 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/38814250 |
TMEM16 and OSCA/TMEM63 proteins share a conserved potential to permeate ions and phospholipids. | Lowry AJ, Liang P, Song M, Wan Y, Pei ZM, Yang H, Zhang Y | eLife | 39495104 | Elife | 2024 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/39495104 |
TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development. | Zhang Y, Le T, Grabau R, Mohseni Z, Kim H, Natale DR, Feng L, Pan H, Yang H | Science advances | 32494719 | Sci Adv | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32494719 |
An Additional Ca(2+) Binding Site Allosterically Controls TMEM16A Activation. | Le SC, Yang H | Cell reports | 33378669 | Cell Rep | 2020 Dec 29 | https://www.ncbi.nlm.nih.gov/pubmed/33378669 |
Corrigendum to "A simple and robust fluorescent labeling method to quantify trophoblast fusion" [Placenta 77 (2019) 16-18]. | Zhang Y, Yang H | Placenta | 31130263 | Placenta | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31130263 |
TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling. | Shan KZ, Le T, Liang P, Dong P, Lowry AJ, Kremmyda P, Claesson-Welsh L, Yang H | Journal of cell science | 38940198 | J Cell Sci | 2024 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/38940198 |
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel. | Yin Y, Le SC, Hsu AL, Borgnia MJ, Yang H, Lee SY | Science (New York, N.Y.) | 30733385 | Science | 2019 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/30733385 |
A simple and robust fluorescent labeling method to quantify trophoblast fusion. | Zhang Y, Yang H | Placenta | 30827351 | Placenta | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30827351 |
Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel. | Zhou Y, Yang H, Cui J, Lingle CJ | The Journal of general physiology | 29025867 | J Gen Physiol | 2017 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/29025867 |
Deciphering and disrupting PIEZO1-TMEM16F interplay in hereditary xerocytosis. | Liang P, Zhang Y, Wan YCS, Ma S, Dong P, Lowry AJ, Francis SJ, Khandelwal S, Delahunty M, Telen MJ, Strouse JJ, Arepally GM, Yang H | Blood | 38033286 | Blood | 2024 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/38033286 |
Gating and Regulatory Mechanisms of TMEM16 Ion Channels and Scramblases. | Le SC, Liang P, Lowry AJ, Yang H | Frontiers in physiology | 34867487 | Front Physiol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34867487 |
Structure-Function of TMEM16 Ion Channels and Lipid Scramblases. | Le SC, Yang H | Advances in experimental medicine and biology | 35138612 | Adv Exp Med Biol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/35138612 |
Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion. | Zhang Y, Liang P, Yang L, Shan KZ, Feng L, Chen Y, Liedtke W, Coyne CB, Yang H | eLife | 35670667 | Elife | 2022 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/35670667 |
Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F. | Le T, Le SC, Zhang Y, Liang P, Yang H | The Journal of biological chemistry | 32709749 | J Biol Chem | 2020 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/32709749 |
Drosophila Subdued is a moonlighting transmembrane protein 16 (TMEM16) that transports ions and phospholipids. | Le T, Le SC, Yang H | The Journal of biological chemistry | 30700552 | J Biol Chem | 2019 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/30700552 |
Molecular underpinning of intracellular pH regulation on TMEM16F. | Liang P, Yang H | The Journal of general physiology | 33346788 | J Gen Physiol | 2021 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/33346788 |
Safety Profile of Rapamycin Perfluorocarbon Nanoparticles for Preventing Cisplatin-Induced Kidney Injury. | Zhou Q, Doherty J, Akk A, Springer LE, Fan P, Spasojevic I, Halade GV, Yang H, Pham CTN, Wickline SA, Pan H | Nanomaterials (Basel, Switzerland) | 35159680 | Nanomaterials (Basel) | 2022 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/35159680 |
TMEM16 and OSCA/TMEM63 proteins share a conserved potential to permeate ions and phospholipids. | Lowry AJ, Liang P, Song M, Serena Wan YC, Pei ZM, Yang H, Zhang Y | bioRxiv : the preprint server for biology | 38370744 | bioRxiv | 2024 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/38370744 |
Improved Yield for the Enzymatic Synthesis of Radiolabeled Nicotinamide Adenine Dinucleotide. | Eller J, Goyal S, Cambronne XA | ACS bio & med chem Au | 36820310 | ACS Bio Med Chem Au | 2023 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/36820310 |
SLC25A51 is a mammalian mitochondrial NAD(+) transporter. | Luongo TS, Eller JM, Lu MJ, Niere M, Raith F, Perry C, Bornstein MR, Oliphint P, Wang L, McReynolds MR, Migaud ME, Rabinowitz JD, Johnson FB, Johnsson K, Ziegler M, Cambronne XA, Baur JA | Nature | 32906142 | Nature | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32906142 |
Layered mechanisms regulating the human mitochondrial NAD+ transporter SLC25A51. | Goyal S, Cambronne XA | Biochemical Society transactions | 38108469 | Biochem Soc Trans | 2023 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/38108469 |
Flow Cytometry Analysis of Free Intracellular NAD(+) Using a Targeted Biosensor. | Eller JM, Stewart ML, Slepian AJ, Markwardt S, Wiedrick J, Cohen MS, Goodman RH, Cambronne XA | Current protocols in cytometry | 30556645 | Curr Protoc Cytom | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30556645 |
Location, Location, Location: Compartmentalization of NAD(+) Synthesis and Functions in Mammalian Cells. | Cambronne XA, Kraus WL | Trends in biochemical sciences | 32595066 | Trends Biochem Sci | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32595066 |
SLC25A51 decouples the mitochondrial NAD(+)/NADH ratio to control proliferation of AML cells. | Lu MJ, Busquets J, Impedovo V, Wilson CN, Chan HR, Chang YT, Matsui W, Tiziani S, Cambronne XA | Cell metabolism | 38354740 | Cell Metab | 2024 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/38354740 |
Pharmacological bypass of NAD(+) salvage pathway protects neurons from chemotherapy-induced degeneration. | Liu HW, Smith CB, Schmidt MS, Cambronne XA, Cohen MS, Migaud ME, Brenner C, Goodman RH | Proceedings of the National Academy of Sciences of the United States of America | 30257945 | Proc Natl Acad Sci U S A | 2018 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/30257945 |
The mitochondrial NAD(+) transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions. | Fu Z, Kim H, Morse PT, Lu MJ, Hüttemann M, Cambronne XA, Zhang K, Zhang R | Metabolism: clinical and experimental | 35932995 | Metabolism | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/35932995 |
Methods for Using a Genetically Encoded Fluorescent Biosensor to Monitor Nuclear NAD<sup/>. | Cohen MS, Stewart ML, Goodman RH, Cambronne XA | Methods in molecular biology (Clifton, N.J.) | 30097882 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30097882 |
Dynamics of SLC25A51 reveal preference for oxidized NAD(+) and substrate led transport. | Goyal S, Paspureddi A, Lu MJ, Chan HR, Lyons SN, Wilson CN, Niere M, Ziegler M, Cambronne XA | EMBO reports | 37575034 | EMBO Rep | 2023 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/37575034 |
Meeting report - Mitotic spindle: from living and synthetic systems to theory. | Simunić J, Subramanian R | Journal of cell science | 31477579 | J Cell Sci | 2019 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/31477579 |
Simultaneous Visualization of the Dynamics of Crosslinked and Single Microtubules In Vitro by TIRF Microscopy. | Mani N, Marchan MF, Subramanian R | Journal of visualized experiments : JoVE | 35253794 | J Vis Exp | 2022 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/35253794 |
Motor guidance by long-range communication on the microtubule highway. | Wijeratne SS, Fiorenza SA, Neary AE, Subramanian R, Betterton MD | Proceedings of the National Academy of Sciences of the United States of America | 35867749 | Proc Natl Acad Sci U S A | 2022 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/35867749 |
Real-Time Visualization of Microtubule and Protofilament-Scale Dynamics in Multi-Microtubule Arrays by Atomic Force Microscopy. | Wijeratne SS, Subramanian R | Current protocols | 37227098 | Curr Protoc | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37227098 |
Active Microphase Separation in Mixtures of Microtubules and Tip-Accumulating Molecular Motors. | Lemma B, Mitchell NP, Subramanian R, Needleman DJ, Dogic Z | Physical review. X | 36643940 | Phys Rev X | 2022 Jul-Sep | https://www.ncbi.nlm.nih.gov/pubmed/36643940 |
Atomic force microscopy reveals distinct protofilament-scale structural dynamics in depolymerizing microtubule arrays. | Wijeratne SS, Marchan MF, Tresback JS, Subramanian R | Proceedings of the National Academy of Sciences of the United States of America | 35101922 | Proc Natl Acad Sci U S A | 2022 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/35101922 |
Micron-scale geometrical features of microtubules as regulators of microtubule organization. | Mani N, Wijeratne SS, Subramanian R | eLife | 34114950 | Elife | 2021 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/34114950 |
Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7. | Jiang S, Mani N, Wilson-Kubalek EM, Ku PI, Milligan RA, Subramanian R | Developmental cell | 31031197 | Dev Cell | 2019 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/31031197 |
Differential regulation of single microtubules and bundles by a three-protein module. | Mani N, Jiang S, Neary AE, Wijeratne SS, Subramanian R | Nature chemical biology | 34083810 | Nat Chem Biol | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34083810 |
Geometry of antiparallel microtubule bundles regulates relative sliding and stalling by PRC1 and Kif4A. | Wijeratne S, Subramanian R | eLife | 30353849 | Elife | 2018 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/30353849 |
Using genome-wide expression compendia to study microorganisms. | Lee AJ, Reiter T, Doing G, Oh J, Hogan DA, Greene CS | Computational and structural biotechnology journal | 36016717 | Comput Struct Biotechnol J | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36016717 |
Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19. | Landay A, Bartley J, Banerjee D, Hargis G, Haynes L, Keshavarzian A, Kuo CL, Kwon OS, Li S, Li S, Oh J, Ozbolat IT, Ucar D, Xu M, Yao X, Unutmaz D, Kuchel GA | Frontiers in aging | 35128530 | Front Aging | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35128530 |
High throughput in situ metagenomic measurement of bacterial replication at ultra-low sequencing coverage. | Emiola A, Oh J | Nature communications | 30470746 | Nat Commun | 2018 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/30470746 |
Strains to go: interactions of the skin microbiome beyond its species. | Caldwell R, Zhou W, Oh J | Current opinion in microbiology | 36242896 | Curr Opin Microbiol | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36242896 |
Bioassay-Driven, Fractionation-Empowered, Focused Metabolomics for Discovering Bacterial Activators of Aryl Hydrocarbon Receptor. | Tian H, Wang L, Hardy R, Kozhaya L, Placek L, Fleming E, Oh J, Unutmaz D, Yao X | Journal of the American Society for Mass Spectrometry | 38308645 | J Am Soc Mass Spectrom | 2024 Mar 6 | https://www.ncbi.nlm.nih.gov/pubmed/38308645 |
Associations of the skin, oral and gut microbiome with aging, frailty and infection risk reservoirs in older adults. | Larson PJ, Zhou W, Santiago A, Driscoll S, Fleming E, Voigt AY, Chun OK, Grady JJ, Kuchel GA, Robison JT, Oh J | Nature aging | 36398033 | Nat Aging | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36398033 |
Selective colonization ability of human fecal microbes in different mouse gut environments. | Zhou W, Chow KH, Fleming E, Oh J | The ISME journal | 30442907 | ISME J | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30442907 |
Metagenomic growth rate inferences of strains in situ. | Emiola A, Zhou W, Oh J | Science advances | 32494636 | Sci Adv | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32494636 |
Differential Hairless Mouse Strain-Specific Susceptibility to Skin Cancer and Sunburn. | Voigt AY, Michaud M, Tsai KY, Oh J, Sundberg JP | The Journal of investigative dermatology | 30742806 | J Invest Dermatol | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30742806 |
State of Residency: Microbial Strain Diversity in the Skin. | Kong HH, Oh J | The Journal of investigative dermatology | 34688614 | J Invest Dermatol | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/34688614 |
Cultivation of common bacterial species and strains from human skin, oral, and gut microbiota. | Fleming E, Pabst V, Scholar Z, Xiong R, Voigt AY, Zhou W, Hoyt A, Hardy R, Peterson A, Beach R, Ondouah-Nzutchi Y, Dong J, Bateman L, Vernon SD, Oh J | BMC microbiology | 34649516 | BMC Microbiol | 2021 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/34649516 |
Skin Microbiome Variation with Cancer Progression in Human Cutaneous Squamous Cell Carcinoma. | Voigt AY, Emiola A, Johnson JS, Fleming ES, Nguyen H, Zhou W, Tsai KY, Fink C, Oh J | The Journal of investigative dermatology | 35390349 | J Invest Dermatol | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/35390349 |
Frailty-associated dysbiosis of human microbiotas in older adults in nursing homes. | Oh J, Robison J, Kuchel GA | Nature aging | 36909933 | Nat Aging | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36909933 |
Challenges in Developing a Human Model System for Skin Microbiome Research. | Larson PJ, Chong D, Fleming E, Oh J | The Journal of investigative dermatology | 32522484 | J Invest Dermatol | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32522484 |
ReprDB and panDB: minimalist databases with maximal microbial representation. | Zhou W, Gay N, Oh J | Microbiome | 29347966 | Microbiome | 2018 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/29347966 |
Skin microbiome attributes associate with biophysical skin ageing. | Zhou W, Fleming E, Legendre G, Roux L, Latreille J, Gendronneau G, Forestier S, Oh J | Experimental dermatology | 37350224 | Exp Dermatol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37350224 |
Publisher Correction: Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery. | Behsaz B, Bode E, Gurevich A, Shi YN, Grundmann F, Acharya D, Caraballo-Rodríguez AM, Bouslimani A, Panitchpakdi M, Linck A, Guan C, Oh J, Dorrestein PC, Bode HB, Pevzner PA, Mohimani H | Nature communications | 34238936 | Nat Commun | 2021 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/34238936 |
Engineering a "detect and destroy" skin probiotic to combat methicillin-resistant Staphylococcus aureus. | Guan C, Larson PJ, Fleming E, Tikhonov AP, Mootien S, Grossman TH, Golino C, Oh J | PloS one | 36520793 | PLoS One | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36520793 |
Large-Scale CRISPRi and Transcriptomics of Staphylococcus epidermidis Identify Genetic Factors Implicated in Lifestyle Versatility. | Spoto M, Riera Puma JP, Fleming E, Guan C, Ondouah Nzutchi Y, Kim D, Oh J | mBio | 36409086 | mBio | 2022 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/36409086 |
Multi-'omics of gut microbiome-host interactions in short- and long-term myalgic encephalomyelitis/chronic fatigue syndrome patients. | Xiong R, Gunter C, Fleming E, Vernon SD, Bateman L, Unutmaz D, Oh J | Cell host & microbe | 36758521 | Cell Host Microbe | 2023 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/36758521 |
Resident risks. | Spoto M, Oh J | Nature microbiology | 30046171 | Nat Microbiol | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30046171 |
Recoding the metagenome: microbiome engineering in situ. | Whitfill T, Oh J | Current opinion in microbiology | 31622928 | Curr Opin Microbiol | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31622928 |
A Universal, Genomewide GuideFinder for CRISPR/Cas9 Targeting in Microbial Genomes. | Spoto M, Guan C, Fleming E, Oh J | mSphere | 32051236 | mSphere | 2020 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/32051236 |
Microbiome modulates immunotherapy response in cutaneous squamous cell carcinoma. | Voigt AY, Walter A, Young T, Graham JP, Batista Bittencourt BM, de Mingo Pulido A, Prieto K, Tsai KY, Sundberg JP, Oh J | bioRxiv : the preprint server for biology | 36747869 | bioRxiv | 2023 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/36747869 |
A commensal strain of Staphylococcus epidermidis protects against skin neoplasia. | Nakatsuji T, Chen TH, Butcher AM, Trzoss LL, Nam SJ, Shirakawa KT, Zhou W, Oh J, Otto M, Fenical W, Gallo RL | Science advances | 29507878 | Sci Adv | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29507878 |
Host-Specific Evolutionary and Transmission Dynamics Shape the Functional Diversification of Staphylococcus epidermidis in Human Skin. | Zhou W, Spoto M, Hardy R, Guan C, Fleming E, Larson PJ, Brown JS, Oh J | Cell | 32004459 | Cell | 2020 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/32004459 |
Microbiome modulates immunotherapy response in cutaneous squamous cell carcinoma. | Voigt AY, Walter A, Young TH, Graham JP, Batista Bittencourt BM, de Mingo Pulido A, Prieto K, Tsai KY, Sundberg JP, Oh J | Experimental dermatology | 37350109 | Exp Dermatol | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37350109 |
A host-microbiota interactome reveals extensive transkingdom connectivity. | Sonnert ND, Rosen CE, Ghazi AR, Franzosa EA, Duncan-Lowey B, González-Hernández JA, Huck JD, Yang Y, Dai Y, Rice TA, Nguyen MT, Song D, Cao Y, Martin AL, Bielecka AA, Fischer S, Guan C, Oh J, Huttenhower C, Ring AM, Palm NW | Nature | 38509360 | Nature | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38509360 |
High-throughput bioprinting of the nasal epithelium using patient-derived nasal epithelial cells. | Deniz Derman I, Yeo M, Castaneda DC, Callender M, Horvath M, Mo Z, Xiong R, Fleming E, Chen P, Peeples ME, Palucka K, Oh J, Ozbolat IT | Biofabrication | 37536321 | Biofabrication | 2023 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/37536321 |
BioMapAI: Artificial Intelligence Multi-Omics Modeling of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome. | Xiong R, Aiken E, Caldwell R, Vernon SD, Kozhaya L, Gunter C, Bateman L, Unutmaz D, Oh J | bioRxiv : the preprint server for biology | 38979186 | bioRxiv | 2025 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/38979186 |
Low-cost detection of norovirus using paper-based cell-free systems and synbody-based viral enrichment. | Ma D, Shen L, Wu K, Diehnelt CW, Green AA | Synthetic biology (Oxford, England) | 30370338 | Synth Biol (Oxf) | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30370338 |
A multiplexed, electrochemical interface for gene-circuit-based sensors. | Sadat Mousavi P, Smith SJ, Chen JB, Karlikow M, Tinafar A, Robinson C, Liu W, Ma D, Green AA, Kelley SO, Pardee K | Nature chemistry | 31767994 | Nat Chem | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31767994 |
Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics. | Jaenes K, Ribeiro da Silva SJ, Vigar JRJ, Wu K, Norouzi M, Bayat P, Karlikow M, Cicek S, Guo Y, Green AA, Pena L, Pardee K | Journal of visualized experiments : JoVE | 35781278 | J Vis Exp | 2022 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/35781278 |
Synthetic bionanotechnology: synthetic biology finds a toehold in nanotechnology. | Green AA | Emerging topics in life sciences | 33523177 | Emerg Top Life Sci | 2019 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/33523177 |
A glucose meter interface for point-of-care gene circuit-based diagnostics. | Amalfitano E, Karlikow M, Norouzi M, Jaenes K, Cicek S, Masum F, Sadat Mousavi P, Guo Y, Tang L, Sydor A, Ma D, Pearson JD, Trcka D, Pinette M, Ambagala A, Babiuk S, Pickering B, Wrana J, Bremner R, Mazzulli T, Sinton D, Brumell JH, Green AA, Pardee K | Nature communications | 33526784 | Nat Commun | 2021 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/33526784 |
Conditional RNA interference in mammalian cells via RNA transactivation. | Zhou Y, Sheng P, Li J, Li Y, Xie M, Green AA | Nature communications | 39127751 | Nat Commun | 2024 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/39127751 |
Rapid, Multiplexed, and Enzyme-Free Nucleic Acid Detection Using Programmable Aptamer-Based RNA Switches. | Yan Z, Eshed A, Tang AA, Arevalos NR, Ticktin ZM, Chaudhary S, Ma D, McCutcheon G, Li Y, Wu K, Saha S, Alcantar-Fernandez J, Moreno-Camacho JL, Campos-Romero A, Collins JJ, Yin P, Green AA | Chem | 39036067 | Chem | 2024 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/39036067 |
De novo-designed translation-repressing riboregulators for multi-input cellular logic. | Kim J, Zhou Y, Carlson PD, Teichmann M, Chaudhary S, Simmel FC, Silver PA, Collins JJ, Lucks JB, Yin P, Green AA | Nature chemical biology | 31686032 | Nat Chem Biol | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31686032 |
Predictable control of RNA lifetime using engineered degradation-tuning RNAs. | Zhang Q, Ma D, Wu F, Standage-Beier K, Chen X, Wu K, Green AA, Wang X | Nature chemical biology | 34155402 | Nat Chem Biol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34155402 |
Multi-arm RNA junctions encoding molecular logic unconstrained by input sequence for versatile cell-free diagnostics. | Ma D, Li Y, Wu K, Yan Z, Tang AA, Chaudhary S, Ticktin ZM, Alcantar-Fernandez J, Moreno-Camacho JL, Campos-Romero A, Green AA | Nature biomedical engineering | 35288660 | Nat Biomed Eng | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35288660 |
Design of RNA-Based Translational Repressors. | Hong S, Park D, Chaudhary S, McCutcheon G, Green AA, Kim J | Methods in molecular biology (Clifton, N.J.) | 35666438 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35666438 |
Closing the loop on crowdsourced science. | Robson JM, Green AA | Proceedings of the National Academy of Sciences of the United States of America | 35687665 | Proc Natl Acad Sci U S A | 2022 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/35687665 |
Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators. | Hong F, Ma D, Wu K, Mina LA, Luiten RC, Liu Y, Yan H, Green AA | Cell | 32109416 | Cell | 2020 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/32109416 |
Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples. | Karlikow M, da Silva SJR, Guo Y, Cicek S, Krokovsky L, Homme P, Xiong Y, Xu T, Calderón-Peláez MA, Camacho-Ortega S, Ma D, de Magalhães JJF, Souza BNRF, de Albuquerque Cabral DG, Jaenes K, Sutyrina P, Ferrante T, Benitez AD, Nipaz V, Ponce P, Rackus DG, Collins JJ, Paiva M, Castellanos JE, Cevallos V, Green AA, Ayres C, Pena L, Pardee K | Nature biomedical engineering | 35256758 | Nat Biomed Eng | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35256758 |
Design of Ribocomputing Devices for Complex Cellular Logic. | McCutcheon G, Chaudhary S, Hong S, Park D, Kim J, Green AA | Methods in molecular biology (Clifton, N.J.) | 35666439 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35666439 |
Rapid and Multiplexed Nucleic Acid Detection using Programmable Aptamer-Based RNA Switches. | Yan Z, Tang AA, Eshed A, Ticktin ZM, Chaudhary S, Ma D, McCutcheon G, Li Y, Wu K, Saha S, Alcantar-Fernandez J, Moreno-Camacho JL, Campos-Romero A, Collins JJ, Yin P, Green AA | medRxiv : the preprint server for health sciences | 37333364 | medRxiv | 2023 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/37333364 |
An Open-Source, Programmable Pneumatic Setup for Operation and Automated Control of Single- and Multi-Layer Microfluidic Devices. | Brower K, Puccinelli R, Markin CJ, Shimko TC, Longwell SA, Cruz B, Gomez-Sjoberg R, Fordyce PM | HardwareX | 30221210 | HardwareX | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30221210 |
Programmable Microfluidic Synthesis of Over One Thousand Uniquely Identifiable Spectral Codes. | Nguyen HQ, Baxter BC, Brower K, Diaz-Botia CA, DeRisi JL, Fordyce PM, Thorn KS | Advanced optical materials | 28936383 | Adv Opt Mater | 2017 Feb 2 | https://www.ncbi.nlm.nih.gov/pubmed/28936383 |
Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads. | Nguyen HQ, Roy J, Harink B, Damle NP, Latorraca NR, Baxter BC, Brower K, Longwell SA, Kortemme T, Thorn KS, Cyert MS, Fordyce PM | eLife | 31282865 | Elife | 2019 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/31282865 |
Double emulsion flow cytometry with high-throughput single droplet isolation and nucleic acid recovery. | Brower KK, Carswell-Crumpton C, Klemm S, Cruz B, Kim G, Calhoun SGK, Nichols L, Fordyce PM | Lab on a chip | 32417874 | Lab Chip | 2020 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/32417874 |
Double Emulsion Picoreactors for High-Throughput Single-Cell Encapsulation and Phenotyping via FACS. | Brower KK, Khariton M, Suzuki PH, Still C 2nd, Kim G, Calhoun SGK, Qi LS, Wang B, Fordyce PM | Analytical chemistry | 32900183 | Anal Chem | 2020 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/32900183 |
micrIO: an open-source autosampler and fraction collector for automated microfluidic input-output. | Longwell SA, Fordyce PM | Lab on a chip | 31701110 | Lab Chip | 2020 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/31701110 |
MRBLES 2.0: High-throughput generation of chemically functionalized spectrally and magnetically encoded hydrogel beads using a simple single-layer microfluidic device. | Feng Y, White AK, Hein JB, Appel EA, Fordyce PM | Microsystems & nanoengineering | 33299601 | Microsyst Nanoeng | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33299601 |
An open-source software analysis package for Microspheres with Ratiometric Barcode Lanthanide Encoding (MRBLEs). | Harink B, Nguyen H, Thorn K, Fordyce P | PloS one | 30901328 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30901328 |
MRBLE-pep Measurements Reveal Accurate Binding Affinities for B56, a PP2A Regulatory Subunit. | Hein JB, Cyert MS, Fordyce PM | ACS measurement science au | 35128539 | ACS Meas Sci Au | 2021 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/35128539 |
A bead-based method for high-throughput mapping of the sequence- and force-dependence of T cell activation. | Feng Y, Zhao X, White AK, Garcia KC, Fordyce PM | Nature methods | 36064771 | Nat Methods | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/36064771 |
Versatility and stability optimization of flow-focusing droplet generators via quality metric-driven design automation. | McIntyre D, Lashkaripour A, Arguijo D, Fordyce P, Densmore D | Lab on a chip | 37909215 | Lab Chip | 2023 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/37909215 |
Protocol for Peptide Synthesis on Spectrally Encoded Beads for MRBLE-pep Assays. | Hein JB, Nguyen HQ, Cyert M, Fordyce PM | Bio-protocol | 33659339 | Bio Protoc | 2020 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/33659339 |
Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices. | Brower K, White AK, Fordyce PM | Journal of visualized experiments : JoVE | 28190039 | J Vis Exp | 2017 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/28190039 |
DeCoDe: degenerate codon design for complete protein-coding DNA libraries. | Shimko TC, Fordyce PM, Orenstein Y | Bioinformatics (Oxford, England) | 32176271 | Bioinformatics | 2020 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/32176271 |
Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification. | Hein JB, Nguyen HT, Garvanska DH, Nasa I, Kruse T, Feng Y, Lopez Mendez B, Davey N, Kettenbach AN, Fordyce PM, Nilsson J | Molecular systems biology | 37916966 | Mol Syst Biol | 2023 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/37916966 |
Design automation of microfluidic single and double emulsion droplets with machine learning. | Lashkaripour A, McIntyre DP, Calhoun SGK, Krauth K, Densmore DM, Fordyce PM | Nature communications | 38167827 | Nat Commun | 2024 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/38167827 |
Machine learning for microfluidic design and control. | McIntyre D, Lashkaripour A, Fordyce P, Densmore D | Lab on a chip | 35904162 | Lab Chip | 2022 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/35904162 |
Systematic characterization of effect of flow rates and buffer compositions on double emulsion droplet volumes and stability. | Calhoun SGK, Brower KK, Suja VC, Kim G, Wang N, McCully AL, Kusumaatmaja H, Fuller GG, Fordyce PM | Lab on a chip | 35593127 | Lab Chip | 2022 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/35593127 |
Tuning T cell receptor sensitivity through catch bond engineering. | Zhao X, Kolawole EM, Chan W, Feng Y, Yang X, Gee MH, Jude KM, Sibener LV, Fordyce PM, Germain RN, Evavold BD, Garcia KC | Science (New York, N.Y.) | 35389803 | Science | 2022 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/35389803 |
A microwell platform for high-throughput longitudinal phenotyping and selective retrieval of organoids. | Sockell A, Wong W, Longwell S, Vu T, Karlsson K, Mokhtari D, Schaepe J, Lo YH, Cornelius V, Kuo C, Van Valen D, Curtis C, Fordyce PM | Cell systems | 37734323 | Cell Syst | 2023 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/37734323 |
On the dependent recognition of some long zinc finger proteins. | Zuo Z, Billings T, Walker M, Petkov PM, Fordyce PM, Stormo GD | Nucleic acids research | 36951113 | Nucleic Acids Res | 2023 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/36951113 |
The palette of techniques for cell cycle analysis. | Eastman AE, Guo S | FEBS letters | 32441778 | FEBS Lett | 2020 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/32441778 |
Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency. | Hernandez C, Wang Z, Ramazanov B, Tang Y, Mehta S, Dambrot C, Lee YW, Tessema K, Kumar I, Astudillo M, Neubert TA, Guo S, Ivanova NB | Cell stem cell | 30146411 | Cell Stem Cell | 2018 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/30146411 |
MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation. | Hu X, Liu ZZ, Chen X, Schulz VP, Kumar A, Hartman AA, Weinstein J, Johnston JF, Rodriguez EC, Eastman AE, Cheng J, Min L, Zhong M, Carroll C, Gallagher PG, Lu J, Schwartz M, King MC, Krause DS, Guo S | Nature communications | 30979898 | Nat Commun | 2019 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/30979898 |
Reprogramming progressive cells display low CAG promoter activity. | Hu X, Wu Q, Zhang J, Kim J, Chen X, Hartman AA, Eastman AE, Park IH, Guo S | Stem cells (Dayton, Ohio) | 33075202 | Stem Cells | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33075202 |
Resolving Cell Cycle Speed in One Snapshot with a Live-Cell Fluorescent Reporter. | Eastman AE, Chen X, Hu X, Hartman AA, Pearlman Morales AM, Yang C, Lu J, Kueh HY, Guo S | Cell reports | 32579930 | Cell Rep | 2020 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/32579930 |
miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism. | Liu J, Guo B, Chen Z, Wang N, Iacovino M, Cheng J, Roden C, Pan W, Khan S, Chen S, Kyba M, Fan R, Guo S, Lu J | Blood | 28053194 | Blood | 2017 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/28053194 |
MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors. | Chen X, Burkhardt DB, Hartman AA, Hu X, Eastman AE, Sun C, Wang X, Zhong M, Krishnaswamy S, Guo S | Nature communications | 31852898 | Nat Commun | 2019 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/31852898 |
Targeting Fibrotic Signaling: A Review of Current Literature and Identification of Future Therapeutic Targets to Improve Wound Healing. | Hetzler PT 3rd, Dash BC, Guo S, Hsia HC | Annals of plastic surgery | 31246672 | Ann Plast Surg | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31246672 |
Cell cycle dynamics in the reprogramming of cellular identity. | Hu X, Eastman AE, Guo S | FEBS letters | 31562821 | FEBS Lett | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31562821 |
YAP Non-cell-autonomously Promotes Pluripotency Induction in Mouse Cells. | Hartman AA, Scalf SM, Zhang J, Hu X, Chen X, Eastman AE, Yang C, Guo S | Stem cell reports | 32243844 | Stem Cell Reports | 2020 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/32243844 |
Serum Response Factor Reduces Gene Expression Noise and Confers Cell State Stability. | Zhang J, Wu Q, Hu X, Wang Y, Lu J, Chakraborty R, Martin KA, Guo S | Stem cells (Dayton, Ohio) | 37386941 | Stem Cells | 2023 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/37386941 |
Seeking Convergence and Cure with New Myeloma Therapies. | Choudhry P, Galligan D, Wiita AP | Trends in cancer | 30064664 | Trends Cancer | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30064664 |
Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma. | Lin YT, Way GP, Barwick BG, Mariano MC, Marcoulis M, Ferguson ID, Driessen C, Boise LH, Greene CS, Wiita AP | Blood advances | 31698452 | Blood Adv | 2019 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/31698452 |
DNA methyltransferase inhibitors upregulate CD38 protein expression and enhance daratumumab efficacy in multiple myeloma. | Choudhry P, Mariano MC, Geng H, Martin TG 3rd, Wolf JL, Wong SW, Shah N, Wiita AP | Leukemia | 31595037 | Leukemia | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31595037 |
Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma. | Huang HH, Ferguson ID, Thornton AM, Bastola P, Lam C, Lin YT, Choudhry P, Mariano MC, Marcoulis MD, Teo CF, Malato J, Phojanakong PJ, Martin TG 3rd, Wolf JL, Wong SW, Shah N, Hann B, Brooks AN, Wiita AP | Nature communications | 32321912 | Nat Commun | 2020 Apr 22 | https://www.ncbi.nlm.nih.gov/pubmed/32321912 |
Surface Proteomics Reveals CD72 as a Target for In Vitro-Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL. | Nix MA, Mandal K, Geng H, Paranjape N, Lin YT, Rivera JM, Marcoulis M, White KL, Whitman JD, Bapat SP, Parker KR, Ramirez J, Deucher A, Phojanokong P, Steri V, Fattahi F, Hann BC, Satpathy AT, Manglik A, Stieglitz E, Wiita AP | Cancer discovery | 33727310 | Cancer Discov | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/33727310 |
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. | Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, Lim SA, Zhou XX, Hobman TC, Kortemme T, Wells JA | Proceedings of the National Academy of Sciences of the United States of America | 33093202 | Proc Natl Acad Sci U S A | 2020 Nov 10 | https://www.ncbi.nlm.nih.gov/pubmed/33093202 |
Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis. | Sarin V, Yu K, Ferguson ID, Gugliemini O, Nix MA, Hann B, Sirota M, Wiita AP | Leukemia | 32123307 | Leukemia | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32123307 |
Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway. | Guo X, Aviles G, Liu Y, Tian R, Unger BA, Lin YT, Wiita AP, Xu K, Correia MA, Kampmann M | Nature | 32132707 | Nature | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32132707 |
CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma. | Ramkumar P, Abarientos AB, Tian R, Seyler M, Leong JT, Chen M, Choudhry P, Hechler T, Shah N, Wong SW, Martin TG, Wolf JL, Roybal KT, Pahl A, Taunton J, Wiita AP, Kampmann M | Blood advances | 32589729 | Blood Adv | 2020 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/32589729 |
Exploring functional protein covariation across single cells using nPOP. | Leduc A, Huffman RG, Cantlon J, Khan S, Slavov N | Genome biology | 36527135 | Genome Biol | 2022 Dec 16 | https://www.ncbi.nlm.nih.gov/pubmed/36527135 |
Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments. | Gatto L, Aebersold R, Cox J, Demichev V, Derks J, Emmott E, Franks AM, Ivanov AR, Kelly RT, Khoury L, Leduc A, MacCoss MJ, Nemes P, Perlman DH, Petelski AA, Rose CM, Schoof EM, Van Eyk J, Vanderaa C, Yates JR 3rd, Slavov N | Nature methods | 36864200 | Nat Methods | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36864200 |
Transformative Opportunities for Single-Cell Proteomics. | Specht H, Slavov N | Journal of proteome research | 29945450 | J Proteome Res | 2018 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/29945450 |
Quantifying Homologous Proteins and Proteoforms. | Malioutov D, Chen T, Airoldi E, Jaffe J, Budnik B, Slavov N | Molecular & cellular proteomics : MCP | 30282776 | Mol Cell Proteomics | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30282776 |
Increasing proteomics throughput. | Slavov N | Nature biotechnology | 33767394 | Nat Biotechnol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33767394 |
Optimizing Accuracy and Depth of Protein Quantification in Experiments Using Isobaric Carriers. | Specht H, Slavov N | Journal of proteome research | 33190502 | J Proteome Res | 2021 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/33190502 |
Multiplexed single-cell proteomics using SCoPE2. | Petelski AA, Emmott E, Leduc A, Huffman RG, Specht H, Perlman DH, Slavov N | Nature protocols | 34716448 | Nat Protoc | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34716448 |
Driving Single Cell Proteomics Forward with Innovation. | Slavov N | Journal of proteome research | 34597050 | J Proteome Res | 2021 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/34597050 |
SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation. | Budnik B, Levy E, Harmange G, Slavov N | Genome biology | 30343672 | Genome Biol | 2018 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/30343672 |
Unpicking the proteome in single cells. | Slavov N | Science (New York, N.Y.) | 32001644 | Science | 2020 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/32001644 |
Voices of biotech research. | Annabi N, Baker M, Boettiger A, Chakraborty D, Chen Y, Corbett KS, Correia B, Dahlman J, de Oliveira T, Ertuerk A, Yanik MF, Henaff E, Huch M, Iliev ID, Jacobs T, Junca H, Keung A, Kolodkin-Gal I, Krishnaswamy S, Lancaster M, Macosko E, Martínez-Núñez MA, Miura K, Molloy J, Cruz AO, Platt RJ, Posey AD Jr, Shao H, Simunovic M, Slavov N, Takebe T, Vandenberghe LH, Varshney RK, Wang J | Nature biotechnology | 33692517 | Nat Biotechnol | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33692517 |
DO-MS: Data-Driven Optimization of Mass Spectrometry Methods. | Huffman RG, Chen A, Specht H, Slavov N | Journal of proteome research | 31081635 | J Proteome Res | 2019 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/31081635 |
Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide. | Saleh D, Najjar M, Zelic M, Shah S, Nogusa S, Polykratis A, Paczosa MK, Gough PJ, Bertin J, Whalen M, Fitzgerald KA, Slavov N, Pasparakis M, Balachandran S, Kelliher M, Mecsas J, Degterev A | Journal of immunology (Baltimore, Md. : 1950) | 28461567 | J Immunol | 2017 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/28461567 |
Increasing the throughput of sensitive proteomics by plexDIA. | Derks J, Leduc A, Wallmann G, Huffman RG, Willetts M, Khan S, Specht H, Ralser M, Demichev V, Slavov N | Nature biotechnology | 35835881 | Nat Biotechnol | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/35835881 |
Integration of a multi-omics stem cell differentiation dataset using a dynamical model. | van den Berg PR, Bérenger-Currias NMLP, Budnik B, Slavov N, Semrau S | PLoS genetics | 37167320 | PLoS Genet | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37167320 |
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. | Specht H, Emmott E, Petelski AA, Huffman RG, Perlman DH, Serra M, Kharchenko P, Koller A, Slavov N | Genome biology | 33504367 | Genome Biol | 2021 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/33504367 |
Ribosome Stoichiometry: From Form to Function. | Emmott E, Jovanovic M, Slavov N | Trends in biochemical sciences | 30473427 | Trends Biochem Sci | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30473427 |
Voices in methods development. | Anikeeva P, Boyden E, Brangwynne C, Cissé II, Fiehn O, Fromme P, Gingras AC, Greene CS, Heard E, Hell SW, Hillman E, Jensen GJ, Karchin R, Kiessling LL, Kleinstiver BP, Knight R, Kukura P, Lancaster MA, Loman N, Looger L, Lundberg E, Luo Q, Miyawaki A, Myers EW Jr, Nolan GP, Picotti P, Reik W, Sauer M, Shalek AK, Shendure J, Slavov N, Tanay A, Troyanskaya O, van Valen D, Wang HW, Yi C, Yin P, Zernicka-Goetz M, Zhuang X | Nature methods | 31562479 | Nat Methods | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31562479 |
Single cell protein analysis for systems biology. | Levy E, Slavov N | Essays in biochemistry | 30072488 | Essays Biochem | 2018 Oct 26 | https://www.ncbi.nlm.nih.gov/pubmed/30072488 |
Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics. | Huffman RG, Leduc A, Wichmann C, Di Gioia M, Borriello F, Specht H, Derks J, Khan S, Khoury L, Emmott E, Petelski AA, Perlman DH, Cox J, Zanoni I, Slavov N | Nature methods | 37012480 | Nat Methods | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37012480 |
New Views of Old Proteins: Clarifying the Enigmatic Proteome. | Burnum-Johnson KE, Conrads TP, Drake RR, Herr AE, Iyengar R, Kelly RT, Lundberg E, MacCoss MJ, Naba A, Nolan GP, Pevzner PA, Rodland KD, Sechi S, Slavov N, Spraggins JM, Van Eyk JE, Vidal M, Vogel C, Walt DR, Kelleher NL | Molecular & cellular proteomics : MCP | 35654359 | Mol Cell Proteomics | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35654359 |
DART-ID increases single-cell proteome coverage. | Chen AT, Franks A, Slavov N | PLoS computational biology | 31260443 | PLoS Comput Biol | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31260443 |
Scaling Up Single-Cell Proteomics. | Slavov N | Molecular & cellular proteomics : MCP | 34808355 | Mol Cell Proteomics | 2022 Jan | https://www.ncbi.nlm.nih.gov/pubmed/34808355 |
Analyzing Ribosome Remodeling in Health and Disease. | Petelski AA, Slavov N | Proteomics | 32820594 | Proteomics | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32820594 |
Measuring Protein Shapes in Living Cells. | Slavov N | Journal of proteome research | 33988997 | J Proteome Res | 2021 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/33988997 |
Approaches for Studying Ribosome Specialization. | Emmott E, Jovanovic M, Slavov N | Trends in biochemical sciences | 30792028 | Trends Biochem Sci | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30792028 |
Single-cell protein analysis by mass spectrometry. | Slavov N | Current opinion in chemical biology | 32599342 | Curr Opin Chem Biol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32599342 |
Post-transcriptional regulation across human tissues. | Franks A, Airoldi E, Slavov N | PLoS computational biology | 28481885 | PLoS Comput Biol | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28481885 |
Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs. | Kern DM, Oh S, Hite RK, Brohawn SG | eLife | 30775971 | Elife | 2019 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/30775971 |
Structural Basis for pH-gating of the K(+) channel TWIK1 at the selectivity filter. | Turney TS, Li V, Brohawn SG | Nature communications | 35680900 | Nat Commun | 2022 Jun 9 | https://www.ncbi.nlm.nih.gov/pubmed/35680900 |
Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes. | Gunasekar SK, Xie L, Kumar A, Hong J, Chheda PR, Kang C, Kern DM, My-Ta C, Maurer J, Heebink J, Gerber EE, Grzesik WJ, Elliot-Hudson M, Zhang Y, Key P, Kulkarni CA, Beals JW, Smith GI, Samuel I, Smith JK, Nau P, Imai Y, Sheldon RD, Taylor EB, Lerner DJ, Norris AW, Klein S, Brohawn SG, Kerns R, Sah R | Nature communications | 35145074 | Nat Commun | 2022 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/35145074 |
Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A. | Hoel CM, Zhang L, Brohawn SG | eLife | 36373655 | Elife | 2022 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/36373655 |
Ultrasound activates mechanosensitive TRAAK K(+) channels through the lipid membrane. | Sorum B, Rietmeijer RA, Gopakumar K, Adesnik H, Brohawn SG | Proceedings of the National Academy of Sciences of the United States of America | 33542098 | Proc Natl Acad Sci U S A | 2021 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/33542098 |
Physical basis for distinct basal and mechanically gated activity of the human K(+) channel TRAAK. | Rietmeijer RA, Sorum B, Li B, Brohawn SG | Neuron | 34390650 | Neuron | 2021 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/34390650 |
SARS-CoV-2 3a expression, purification, and reconstitution into lipid nanodiscs. | Kern DM, Brohawn SG | Methods in enzymology | 34099172 | Methods Enzymol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34099172 |
Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex. | Wang JY, Hoel CM, Al-Shayeb B, Banfield JF, Brohawn SG, Doudna JA | Nature communications | 33958590 | Nat Commun | 2021 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/33958590 |
Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca(2+)-dependent switch from intra- to intermembrane dimerization. | Li B, Hoel CM, Brohawn SG | Nature communications | 34824283 | Nat Commun | 2021 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/34824283 |
Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs. | Tucker K, Sridharan S, Adesnik H, Brohawn SG | Nature communications | 35977941 | Nat Commun | 2022 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/35977941 |
Studying Mechanosensitivity of Two-Pore Domain K(+) Channels in Cellular and Reconstituted Proteoliposome Membranes. | Del Mármol J, Rietmeijer RA, Brohawn SG | Methods in molecular biology (Clifton, N.J.) | 29058189 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29058189 |
Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs. | Kern DM, Sorum B, Mali SS, Hoel CM, Sridharan S, Remis JP, Toso DB, Kotecha A, Bautista DM, Brohawn SG | Nature structural & molecular biology | 34158638 | Nat Struct Mol Biol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34158638 |
Author Correction: Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs. | Kern DM, Sorum B, Mali SS, Hoel CM, Sridharan S, Remis JP, Toso DB, Kotecha A, Bautista DM, Brohawn SG | Nature structural & molecular biology | 34285420 | Nat Struct Mol Biol | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34285420 |
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. | Brohawn SG, Wang W, Handler A, Campbell EB, Schwarz JR, MacKinnon R | eLife | 31674909 | Elife | 2019 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/31674909 |
Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs. | Kern DM, Sorum B, Mali SS, Hoel CM, Sridharan S, Remis JP, Toso DB, Kotecha A, Bautista DM, Brohawn SG | bioRxiv : the preprint server for biology | 32587976 | bioRxiv | 2021 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/32587976 |
Structural basis for pH gating of the two-pore domain K(+) channel TASK2. | Li B, Rietmeijer RA, Brohawn SG | Nature | 32999458 | Nature | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32999458 |
Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. | Reid MS, Kern DM, Brohawn SG | eLife | 32286222 | Elife | 2020 Apr 14 | https://www.ncbi.nlm.nih.gov/pubmed/32286222 |
Replication timing alterations in leukemia affect clinically relevant chromosome domains. | Rivera-Mulia JC, Sasaki T, Trevilla-Garcia C, Nakamichi N, Knapp DJHF, Hammond CA, Chang BH, Tyner JW, Devidas M, Zimmerman J, Klein KN, Somasundaram V, Druker BJ, Gruber TA, Koren A, Eaves CJ, Gilbert DM | Blood advances | 31698451 | Blood Adv | 2019 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/31698451 |
Positive and Negative Regulation of DNA Replication Initiation. | Ding Q, Koren A | Trends in genetics : TIG | 32739030 | Trends Genet | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32739030 |
Cancer Mutational Processes Vary in Their Association with Replication Timing and Chromatin Accessibility. | Yaacov A, Vardi O, Blumenfeld B, Greenberg A, Massey DJ, Koren A, Adar S, Simon I, Rosenberg S | Cancer research | 34702725 | Cancer Res | 2021 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/34702725 |
Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. | Caballero M, Ge T, Rebelo AR, Seo S, Kim S, Brooks K, Zuccaro M, Kanagaraj R, Vershkov D, Kim D, Smogorzewska A, Smolka M, Benvenisty N, West SC, Egli D, Mace EM, Koren A | Human molecular genetics | 35394024 | Hum Mol Genet | 2022 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/35394024 |
TIGER: inferring DNA replication timing from whole-genome sequence data. | Koren A, Massey DJ, Bracci AN | Bioinformatics (Oxford, England) | 33704387 | Bioinformatics | 2021 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/33704387 |
Cell-type specificity of the human mutation landscape with respect to DNA replication dynamics. | Caballero M, Boos D, Koren A | Cell genomics | 37388911 | Cell Genom | 2023 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/37388911 |
Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer. | Webster ALH, Sanders MA, Patel K, Dietrich R, Noonan RJ, Lach FP, White RR, Goldfarb A, Hadi K, Edwards MM, Donovan FX, Hoogenboezem RM, Jung M, Sridhar S, Wiley TF, Fedrigo O, Tian H, Rosiene J, Heineman T, Kennedy JA, Bean L, Rosti RO, Tryon R, Gonzalez AM, Rosenberg A, Luo JD, Carroll TS, Shroff S, Beaumont M, Velleuer E, Rastatter JC, Wells SI, Surrallés J, Bagby G, MacMillan ML, Wagner JE, Cancio M, Boulad F, Scognamiglio T, Vaughan R, Beaumont KG, Koren A, Imielinski M, Chandrasekharappa SC, Auerbach AD, Singh B, Kutler DI, Campbell PJ, Smogorzewska A | Nature | 36450981 | Nature | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36450981 |
Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication. | Jones MJK, Gelot C, Munk S, Koren A, Kawasoe Y, George KA, Santos RE, Olsen JV, McCarroll SA, Frattini MG, Takahashi TS, Jallepalli PV | Molecular cell | 33545059 | Mol Cell | 2021 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/33545059 |
Mutation Rate Variability across Human Y-Chromosome Haplogroups. | Ding Q, Hu Y, Koren A, Clark AG | Molecular biology and evolution | 33049047 | Mol Biol Evol | 2021 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/33049047 |
Germline DNA replication timing shapes mammalian genome composition. | Yehuda Y, Blumenfeld B, Mayorek N, Makedonski K, Vardi O, Cohen-Daniel L, Mansour Y, Baror-Sebban S, Masika H, Farago M, Berger M, Carmi S, Buganim Y, Koren A, Simon I | Nucleic acids research | 29986092 | Nucleic Acids Res | 2018 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/29986092 |
Germline Structural Variations Are Preferential Sites of DNA Replication Timing Plasticity during Development. | Hulke ML, Siefert JC, Sansam CL, Koren A | Genome biology and evolution | 31076752 | Genome Biol Evol | 2019 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/31076752 |
Genomic methods for measuring DNA replication dynamics. | Hulke ML, Massey DJ, Koren A | Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology | 31848781 | Chromosome Res | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31848781 |
The genetic architecture of DNA replication timing in human pluripotent stem cells. | Ding Q, Edwards MM, Wang N, Zhu X, Bracci AN, Hulke ML, Hu Y, Tong Y, Hsiao J, Charvet CJ, Ghosh S, Handsaker RE, Eggan K, Merkle FT, Gerhardt J, Egli D, Clark AG, Koren A | Nature communications | 34799581 | Nat Commun | 2021 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/34799581 |
Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells. | Deshpande M, Paniza T, Jalloul N, Nanjangud G, Twarowski J, Koren A, Zaninovic N, Zhan Q, Chadalavada K, Malkova A, Khiabanian H, Madireddy A, Rosenwaks Z, Gerhardt J | Molecular cell | 36099913 | Mol Cell | 2022 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/36099913 |
High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control. | Massey DJ, Koren A | Nature communications | 35504890 | Nat Commun | 2022 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/35504890 |
Telomere-to-telomere human DNA replication timing profiles. | Massey DJ, Koren A | Scientific reports | 35688856 | Sci Rep | 2022 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/35688856 |
Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes. | Rivas MA, Durmaz C, Kloetgen A, Chin CR, Chen Z, Bhinder B, Koren A, Viny AD, Scharer CD, Boss JM, Elemento O, Mason CE, Melnick AM | Frontiers in immunology | 34621263 | Front Immunol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34621263 |
Replication timing analysis in polyploid cells reveals Rif1 uses multiple mechanisms to promote underreplication in Drosophila. | Das S, Caballero M, Kolesnikova T, Zhimulev I, Koren A, Nordman J | Genetics | 34740250 | Genetics | 2021 Nov 5 | https://www.ncbi.nlm.nih.gov/pubmed/34740250 |
Next-Generation Sequencing Enables Spatiotemporal Resolution of Human Centromere Replication Timing. | Massey DJ, Kim D, Brooks KE, Smolka MB, Koren A | Genes | 30987063 | Genes (Basel) | 2019 Apr 2 | https://www.ncbi.nlm.nih.gov/pubmed/30987063 |
The landscape of somatic mutations in lymphoblastoid cell lines. | Caballero M, Koren A | Cell genomics | 37388907 | Cell Genom | 2023 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/37388907 |
Assembly of a nucleus-like structure during viral replication in bacteria. | Chaikeeratisak V, Nguyen K, Khanna K, Brilot AF, Erb ML, Coker JK, Vavilina A, Newton GL, Buschauer R, Pogliano K, Villa E, Agard DA, Pogliano J | Science (New York, N.Y.) | 28082593 | Science | 2017 Jan 13 | https://www.ncbi.nlm.nih.gov/pubmed/28082593 |
The In Situ Structure of Parkinson's Disease-Linked LRRK2. | Watanabe R, Buschauer R, Böhning J, Audagnotto M, Lasker K, Lu TW, Boassa D, Taylor S, Villa E | Cell | 32783917 | Cell | 2020 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/32783917 |
Shaping an Endospore: Architectural Transformations During Bacillus subtilis Sporulation. | Khanna K, Lopez-Garrido J, Pogliano K | Annual review of microbiology | 32660383 | Annu Rev Microbiol | 2020 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/32660383 |
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. | Lu S, Ye Q, Singh D, Cao Y, Diedrich JK, Yates JR 3rd, Villa E, Cleveland DW, Corbett KD | Nature communications | 33479198 | Nat Commun | 2021 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/33479198 |
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. | Yu H, Lu S, Gasior K, Singh D, Vazquez-Sanchez S, Tapia O, Toprani D, Beccari MS, Yates JR 3rd, Da Cruz S, Newby JM, Lafarga M, Gladfelter AS, Villa E, Cleveland DW | Science (New York, N.Y.) | 33335017 | Science | 2021 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/33335017 |
Challenges of Integrating Stochastic Dynamics and Cryo-Electron Tomograms in Whole-Cell Simulations. | Earnest TM, Watanabe R, Stone JE, Mahamid J, Baumeister W, Villa E, Luthey-Schulten Z | The journal of physical chemistry. B | 28291359 | J Phys Chem B | 2017 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/28291359 |
The molecular architecture of engulfment during Bacillus subtilis sporulation. | Khanna K, Lopez-Garrido J, Zhao Z, Watanabe R, Yuan Y, Sugie J, Pogliano K, Villa E | eLife | 31282858 | Elife | 2019 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/31282858 |
Viral Capsid Trafficking along Treadmilling Tubulin Filaments in Bacteria. | Chaikeeratisak V, Khanna K, Nguyen KT, Sugie J, Egan ME, Erb ML, Vavilina A, Nonejuie P, Nieweglowska E, Pogliano K, Agard DA, Villa E, Pogliano J | Cell | 31199917 | Cell | 2019 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/31199917 |
Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography. | Wagner FR, Watanabe R, Schampers R, Singh D, Persoon H, Schaffer M, Fruhstorfer P, Plitzko J, Villa E | Nature protocols | 32405053 | Nat Protoc | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32405053 |
Chromosome Translocation Inflates Bacillus Forespores and Impacts Cellular Morphology. | Lopez-Garrido J, Ojkic N, Khanna K, Wagner FR, Villa E, Endres RG, Pogliano K | Cell | 29425492 | Cell | 2018 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/29425492 |
Generating Chromosome Geometries in a Minimal Cell From Cryo-Electron Tomograms and Chromosome Conformation Capture Maps. | Gilbert BR, Thornburg ZR, Lam V, Rashid FM, Glass JI, Villa E, Dame RT, Luthey-Schulten Z | Frontiers in molecular biosciences | 34368224 | Front Mol Biosci | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/34368224 |
Comprehensive structure and functional adaptations of the yeast nuclear pore complex. | Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP | Cell | 34982960 | Cell | 2022 Jan 20 | https://www.ncbi.nlm.nih.gov/pubmed/34982960 |
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems. | Lasker K, Boeynaems S, Lam V, Scholl D, Stainton E, Briner A, Jacquemyn M, Daelemans D, Deniz A, Villa E, Holehouse AS, Gitler AD, Shapiro L | Nature communications | 36163138 | Nat Commun | 2022 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/36163138 |
ExoSloNano: Multi-Modal Nanogold Tags for identification of Macromolecules in Live Cells & Cryo-Electron Tomograms. | Young LN, Sherrard A, Zhou H, Shaikh F, Hutchings J, Riggi M, Rosen MK, Giraldez AJ, Villa E | bioRxiv : the preprint server for biology | 39416124 | bioRxiv | 2024 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/39416124 |
The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. | Lu S, Ye Q, Singh D, Villa E, Cleveland DW, Corbett KD | bioRxiv : the preprint server for biology | 32766587 | bioRxiv | 2020 Jul 31 | https://www.ncbi.nlm.nih.gov/pubmed/32766587 |
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction. | Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE | Nature | 32814344 | Nature | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/32814344 |
Practical Approaches for Cryo-FIB Milling and Applications for Cellular Cryo-Electron Tomography. | Lam V, Villa E | Methods in molecular biology (Clifton, N.J.) | 33367999 | Methods Mol Biol | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/33367999 |
Entropy-regularized deconvolution of cellular cryotransmission electron tomograms. | Croxford M, Elbaum M, Arigovindan M, Kam Z, Agard D, Villa E, Sedat J | Proceedings of the National Academy of Sciences of the United States of America | 34876518 | Proc Natl Acad Sci U S A | 2021 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/34876518 |
The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC). | Rale MJ, Romer B, Mahon BP, Travis SM, Petry S | eLife | 36515268 | Elife | 2022 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/36515268 |
How TPX2 helps microtubules branch out. | Alfaro-Aco R, Petry S | Cell cycle (Georgetown, Tex.) | 28767311 | Cell Cycle | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28767311 |
Biochemical reconstitution of branching microtubule nucleation. | Alfaro-Aco R, Thawani A, Petry S | eLife | 31933480 | Elife | 2020 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/31933480 |
Visualizing and Analyzing Branching Microtubule Nucleation Using Meiotic Xenopus Egg Extracts and TIRF Microscopy. | King M, Petry S | Methods in molecular biology (Clifton, N.J.) | 27193844 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27193844 |
Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules. | Song JG, King MR, Zhang R, Kadzik RS, Thawani A, Petry S | The Journal of cell biology | 29875259 | J Cell Biol | 2018 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/29875259 |
Building the Microtubule Cytoskeleton Piece by Piece. | Alfaro-Aco R, Petry S | The Journal of biological chemistry | 25957410 | J Biol Chem | 2015 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/25957410 |
The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy. | Thawani A, Rale MJ, Coudray N, Bhabha G, Stone HA, Shaevitz JW, Petry S | eLife | 32538784 | Elife | 2020 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/32538784 |
Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation. | King MR, Petry S | Nature communications | 31937751 | Nat Commun | 2020 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/31937751 |
A hydrodynamic instability drives protein droplet formation on microtubules to nucleate branches. | Setru SU, Gouveia B, Alfaro-Aco R, Shaevitz JW, Stone HA, Petry S | Nature physics | 35211183 | Nat Phys | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35211183 |
Structural basis of protein condensation on microtubules underlying branching microtubule nucleation. | Guo C, Alfaro-Aco R, Zhang C, Russell RW, Petry S, Polenova T | Nature communications | 37344496 | Nat Commun | 2023 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/37344496 |
Microtubule nucleation for spindle assembly: one molecule at a time. | Kraus J, Alfaro-Aco R, Gouveia B, Petry S | Trends in biochemical sciences | 37482516 | Trends Biochem Sci | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37482516 |
Confinement size determines the architecture of Ran-induced microtubule networks. | Gai Y, Cook B, Setru S, Stone HA, Petry S | Soft matter | 34041514 | Soft Matter | 2021 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/34041514 |
Phase Transitioning the Centrosome into a Microtubule Nucleator. | Rale MJ, Kadzik RS, Petry S | Biochemistry | 29256606 | Biochemistry | 2018 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/29256606 |
Mechanisms of Mitotic Spindle Assembly. | Petry S | Annual review of biochemistry | 27145846 | Annu Rev Biochem | 2016 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/27145846 |
Spatiotemporal organization of branched microtubule networks. | Thawani A, Stone HA, Shaevitz JW, Petry S | eLife | 31066674 | Elife | 2019 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/31066674 |
Acentrosomal spindles assemble from branching microtubule nucleation near chromosomes in Xenopus laevis egg extract. | Gouveia B, Setru SU, King MR, Hamlin A, Stone HA, Shaevitz JW, Petry S | Nature communications | 37344488 | Nat Commun | 2023 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/37344488 |
Molecular insight into how γ-TuRC makes microtubules. | Thawani A, Petry S | Journal of cell science | 34297125 | J Cell Sci | 2021 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/34297125 |
How Microtubules Build the Spindle Branch by Branch. | Travis SM, Mahon BP, Petry S | Annual review of cell and developmental biology | 35759800 | Annu Rev Cell Dev Biol | 2022 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/35759800 |
Structural analysis of the role of TPX2 in branching microtubule nucleation. | Alfaro-Aco R, Thawani A, Petry S | The Journal of cell biology | 28264915 | J Cell Biol | 2017 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/28264915 |
Dissecting Protein Complexes in Branching Microtubule Nucleation Using Meiotic Xenopus Egg Extracts. | Song JG, Petry S | Cold Spring Harbor protocols | 29321281 | Cold Spring Harb Protoc | 2018 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/29321281 |
XMAP215 is a microtubule nucleation factor that functions synergistically with the γ-tubulin ring complex. | Thawani A, Kadzik RS, Petry S | Nature cell biology | 29695792 | Nat Cell Biol | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29695792 |
Selective binding of a toxin and phosphatidylinositides to a mammalian potassium channel. | Liu Y, LoCaste CE, Liu W, Poltash ML, Russell DH, Laganowsky A | Nature communications | 30902995 | Nat Commun | 2019 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/30902995 |
Variable-Temperature ESI-IMS-MS Analysis of Myohemerythrin Reveals Ligand Losses, Unfolding, and a Non-Native Disulfide Bond. | Woodall DW, El-Baba TJ, Fuller DR, Liu W, Brown CJ, Laganowsky A, Russell DH, Clemmer DE | Analytical chemistry | 31038926 | Anal Chem | 2019 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/31038926 |
Investigation of Protein-Lipid Interactions Using Native Mass Spectrometry. | Cong X, Patrick JW, Liu Y, Liang X, Liu W, Laganowsky A | Methods in molecular biology (Clifton, N.J.) | 34718990 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/34718990 |
Small molecule peptidomimetic trypsin inhibitors: validation of an EKO binding mode, but with a twist. | Lyu RL, Joy S, Packianathan C, Laganowsky A, Burgess K | Organic & biomolecular chemistry | 35225309 | Org Biomol Chem | 2022 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/35225309 |
Entropy in the Molecular Recognition of Membrane Protein-Lipid Interactions. | Qiao P, Schrecke S, Walker T, McCabe JW, Lyu J, Zhu Y, Zhang T, Kumar S, Clemmer D, Russell DH, Laganowsky A | The journal of physical chemistry letters | 34928154 | J Phys Chem Lett | 2021 Dec 30 | https://www.ncbi.nlm.nih.gov/pubmed/34928154 |
Development and Evaluation of a Reverse-Entry Ion Source Orbitrap Mass Spectrometer. | Poltash ML, McCabe JW, Patrick JW, Laganowsky A, Russell DH | Journal of the American Society for Mass Spectrometry | 29796735 | J Am Soc Mass Spectrom | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29796735 |
First-Principles Collision Cross Section Measurements of Large Proteins and Protein Complexes. | McCabe JW, Mallis CS, Kocurek KI, Poltash ML, Shirzadeh M, Hebert MJ, Fan L, Walker TE, Zheng X, Jiang T, Dong S, Lin CW, Laganowsky A, Russell DH | Analytical chemistry | 32662991 | Anal Chem | 2020 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/32662991 |
Implementing Digital-Waveform Technology for Extended m/z Range Operation on a Native Dual-Quadrupole FT-IM-Orbitrap Mass Spectrometer. | McCabe JW, Jones BJ, Walker TE, Schrader RL, Huntley AP, Lyu J, Hoffman NM, Anderson GA, Reilly PTA, Laganowsky A, Wysocki VH, Russell DH | Journal of the American Society for Mass Spectrometry | 34797072 | J Am Soc Mass Spectrom | 2021 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/34797072 |
Allosteric modulation of protein-protein interactions by individual lipid binding events. | Cong X, Liu Y, Liu W, Liang X, Laganowsky A | Nature communications | 29259178 | Nat Commun | 2017 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/29259178 |
THE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY-MASS SPECTROMETRY. | McCabe JW, Hebert MJ, Shirzadeh M, Mallis CS, Denton JK, Walker TE, Russell DH | Mass spectrometry reviews | 32608033 | Mass Spectrom Rev | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/32608033 |
A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins. | Khan D, Lee D, Gulten G, Aggarwal A, Wofford J, Krieger I, Tripathi A, Patrick JW, Eckert DM, Laganowsky A, Sacchettini J, Lindahl P, Bankaitis VA | eLife | 32780017 | Elife | 2020 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/32780017 |
Development of Native MS Capabilities on an Extended Mass Range Q-TOF MS. | Mallis CS, Zheng X, Qiu X, McCabe JW, Shirzadeh M, Lyu J, Laganowsky A, Russell DH | International journal of mass spectrometry | 33162786 | Int J Mass Spectrom | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33162786 |
Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding. | McCabe JW, Shirzadeh M, Walker TE, Lin CW, Jones BJ, Wysocki VH, Barondeau DP, Clemmer DE, Laganowsky A, Russell DH | Analytical chemistry | 33904705 | Anal Chem | 2021 May 11 | https://www.ncbi.nlm.nih.gov/pubmed/33904705 |
Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants. | Moghadamchargari Z, Shirzadeh M, Liu C, Schrecke S, Packianathan C, Russell DH, Zhao M, Laganowsky A | Proceedings of the National Academy of Sciences of the United States of America | 33723061 | Proc Natl Acad Sci U S A | 2021 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/33723061 |
Surface induced dissociation as a tool to study membrane protein complexes. | Harvey SR, Liu Y, Liu W, Wysocki VH, Laganowsky A | Chemical communications (Cambridge, England) | 28243658 | Chem Commun (Camb) | 2017 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/28243658 |
Generation of Charge-Reduced Ions of Membrane Protein Complexes for Native Ion Mobility Mass Spectrometry Studies. | Patrick JW, Laganowsky A | Journal of the American Society for Mass Spectrometry | 30887461 | J Am Soc Mass Spectrom | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30887461 |
Topological Analysis of Transthyretin Disassembly Mechanism: Surface-Induced Dissociation Reveals Hidden Reaction Pathways. | Shirzadeh M, Boone CD, Laganowsky A, Russell DH | Analytical chemistry | 30642177 | Anal Chem | 2019 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/30642177 |
Evidence for Many Unique Solution Structures for Chymotrypsin Inhibitor 2: A Thermodynamic Perspective Derived from vT-ESI-IMS-MS Measurements. | Raab SA, El-Baba TJ, Woodall DW, Liu W, Liu Y, Baird Z, Hales DA, Laganowsky A, Russell DH, Clemmer DE | Journal of the American Chemical Society | 32866376 | J Am Chem Soc | 2020 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/32866376 |
Allostery revealed within lipid binding events to membrane proteins. | Patrick JW, Boone CD, Liu W, Conover GM, Liu Y, Cong X, Laganowsky A | Proceedings of the National Academy of Sciences of the United States of America | 29507234 | Proc Natl Acad Sci U S A | 2018 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/29507234 |
Protons Are Fast and Smart; Proteins Are Slow and Dumb: On the Relationship of Electrospray Ionization Charge States and Conformations. | Raab SA, El-Baba TJ, Laganowsky A, Russell DH, Valentine SJ, Clemmer DE | Journal of the American Society for Mass Spectrometry | 34151568 | J Am Soc Mass Spectrom | 2021 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/34151568 |
Cupric Ions Selectively Modulate TRAAK-Phosphatidylserine Interactions. | Zhu Y, Schrecke S, Tang S, Odenkirk MT, Walker T, Stover L, Lyu J, Zhang T, Russell D, Baker ES, Yan X, Laganowsky A | Journal of the American Chemical Society | 35421309 | J Am Chem Soc | 2022 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/35421309 |
Structural basis for lipid and copper regulation of the ABC transporter MsbA. | Lyu J, Liu C, Zhang T, Schrecke S, Elam NP, Packianathan C, Hochberg GKA, Russell D, Zhao M, Laganowsky A | Nature communications | 36435815 | Nat Commun | 2022 Nov 26 | https://www.ncbi.nlm.nih.gov/pubmed/36435815 |
Enhanced Characterization of Membrane Protein Complexes by Ultraviolet Photodissociation Mass Spectrometry. | Sipe SN, Patrick JW, Laganowsky A, Brodbelt JS | Analytical chemistry | 31765130 | Anal Chem | 2020 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/31765130 |
Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1. | Bergdoll LA, Lerch MT, Patrick JW, Belardo K, Altenbach C, Bisignano P, Laganowsky A, Grabe M, Hubbell WL, Abramson J | Proceedings of the National Academy of Sciences of the United States of America | 29279396 | Proc Natl Acad Sci U S A | 2018 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/29279396 |
Insight into the Phospholipid-Binding Preferences of Kir3.4. | Qiao P, Schrecke S, Lyu J, Zhu Y, Zhang T, Benavides A, Laganowsky A | Biochemistry | 34846128 | Biochemistry | 2021 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/34846128 |
Selective regulation of human TRAAK channels by biologically active phospholipids. | Schrecke S, Zhu Y, McCabe JW, Bartz M, Packianathan C, Zhao M, Zhou M, Russell D, Laganowsky A | Nature chemical biology | 32989299 | Nat Chem Biol | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32989299 |
Fourier Transform-Ion Mobility-Orbitrap Mass Spectrometer: A Next-Generation Instrument for Native Mass Spectrometry. | Poltash ML, McCabe JW, Shirzadeh M, Laganowsky A, Clowers BH, Russell DH | Analytical chemistry | 30091588 | Anal Chem | 2018 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/30091588 |
Discovery of Potent Charge-Reducing Molecules for Native Ion Mobility Mass Spectrometry Studies. | Lyu J, Liu Y, McCabe JW, Schrecke S, Fang L, Russell DH, Laganowsky A | Analytical chemistry | 32672445 | Anal Chem | 2020 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/32672445 |
Native IM-Orbitrap MS: Resolving What Was Hidden. | Poltash ML, McCabe JW, Shirzadeh M, Laganowsky A, Russell DH | Trends in analytical chemistry : TRAC | 32189816 | Trends Analyt Chem | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32189816 |
Variable-Temperature Native Mass Spectrometry for Studies of Protein Folding, Stabilities, Assembly, and Molecular Interactions. | Laganowsky A, Clemmer DE, Russell DH | Annual review of biophysics | 34932911 | Annu Rev Biophys | 2022 May 9 | https://www.ncbi.nlm.nih.gov/pubmed/34932911 |
Intrinsic GTPase Activity of K-RAS Monitored by Native Mass Spectrometry. | Moghadamchargari Z, Huddleston J, Shirzadeh M, Zheng X, Clemmer DE, M Raushel F, Russell DH, Laganowsky A | Biochemistry | 31306575 | Biochemistry | 2019 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/31306575 |
Double and triple thermodynamic mutant cycles reveal the basis for specific MsbA-lipid interactions. | Lyu J, Zhang T, Marty MT, Clemmer D, Russell DH, Laganowsky A | bioRxiv : the preprint server for biology | 37461710 | bioRxiv | 2023 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/37461710 |
Double and triple thermodynamic mutant cycles reveal the basis for specific MsbA-lipid interactions. | Lyu J, Zhang T, Marty MT, Clemmer D, Russell DH, Laganowsky A | eLife | 38252560 | Elife | 2024 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/38252560 |
Denoising genome-wide histone ChIP-seq with convolutional neural networks. | Koh PW, Pierson E, Kundaje A | Bioinformatics (Oxford, England) | 28881977 | Bioinformatics | 2017 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/28881977 |
Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study. | Wainberg M, Mahajan A, Kundaje A, McCarthy MI, Ingelsson E, Sinnott-Armstrong N, Rivas MA | PLoS medicine | 31821322 | PLoS Med | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31821322 |
GenomeDISCO: a concordance score for chromosome conformation capture experiments using random walks on contact map graphs. | Ursu O, Boley N, Taranova M, Wang YXR, Yardimci GG, Stafford Noble W, Kundaje A | Bioinformatics (Oxford, England) | 29554289 | Bioinformatics | 2018 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/29554289 |
Transcription-dependent domain-scale three-dimensional genome organization in the dinoflagellate Breviolum minutum. | Marinov GK, Trevino AE, Xiang T, Kundaje A, Grossman AR, Greenleaf WJ | Nature genetics | 33927397 | Nat Genet | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33927397 |
The chromatin landscape of the euryarchaeon Haloferax volcanii. | Marinov GK, Bagdatli ST, Wu T, He C, Kundaje A, Greenleaf WJ | Genome biology | 37932847 | Genome Biol | 2023 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/37932847 |
Base-resolution models of transcription-factor binding reveal soft motif syntax. | Avsec Ž, Weilert M, Shrikumar A, Krueger S, Alexandari A, Dalal K, Fropf R, McAnany C, Gagneur J, Kundaje A, Zeitlinger J | Nature genetics | 33603233 | Nat Genet | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33603233 |
The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation. | Kim DS, Risca VI, Reynolds DL, Chappell J, Rubin AJ, Jung N, Donohue LKH, Lopez-Pajares V, Kathiria A, Shi M, Zhao Z, Deep H, Sharmin M, Rao D, Lin S, Chang HY, Snyder MP, Greenleaf WJ, Kundaje A, Khavari PA | Nature genetics | 34650237 | Nat Genet | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34650237 |
fastISM: performant in silico saturation mutagenesis for convolutional neural networks. | Nair S, Shrikumar A, Schreiber J, Kundaje A | Bioinformatics (Oxford, England) | 35238376 | Bioinformatics | 2022 Apr 28 | https://www.ncbi.nlm.nih.gov/pubmed/35238376 |
Transparency and reproducibility in artificial intelligence. | Haibe-Kains B, Adam GA, Hosny A, Khodakarami F, Massive Analysis Quality Control (MAQC) Society Board of Directors, Waldron L, Wang B, McIntosh C, Goldenberg A, Kundaje A, Greene CS, Broderick T, Hoffman MM, Leek JT, Korthauer K, Huber W, Brazma A, Pineau J, Tibshirani R, Hastie T, Ioannidis JPA, Quackenbush J, Aerts HJWL | Nature | 33057217 | Nature | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33057217 |
Learning cis-regulatory principles of ADAR-based RNA editing from CRISPR-mediated mutagenesis. | Liu X, Sun T, Shcherbina A, Li Q, Jarmoskaite I, Kappel K, Ramaswami G, Das R, Kundaje A, Li JB | Nature communications | 33846332 | Nat Commun | 2021 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/33846332 |
Deciphering regulatory DNA sequences and noncoding genetic variants using neural network models of massively parallel reporter assays. | Movva R, Greenside P, Marinov GK, Nair S, Shrikumar A, Kundaje A | PloS one | 31206543 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31206543 |
Discovering epistatic feature interactions from neural network models of regulatory DNA sequences. | Greenside P, Shimko T, Fordyce P, Kundaje A | Bioinformatics (Oxford, England) | 30423062 | Bioinformatics | 2018 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/30423062 |
GkmExplain: fast and accurate interpretation of nonlinear gapped k-mer SVMs. | Shrikumar A, Prakash E, Kundaje A | Bioinformatics (Oxford, England) | 31510661 | Bioinformatics | 2019 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/31510661 |
MTSplice predicts effects of genetic variants on tissue-specific splicing. | Cheng J, Çelik MH, Kundaje A, Gagneur J | Genome biology | 33789710 | Genome Biol | 2021 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/33789710 |
Domain-adaptive neural networks improve cross-species prediction of transcription factor binding. | Cochran K, Srivastava D, Shrikumar A, Balsubramani A, Hardison RC, Kundaje A, Mahony S | Genome research | 35042722 | Genome Res | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35042722 |
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease. | Ameen M, Sundaram L, Shen M, Banerjee A, Kundu S, Nair S, Shcherbina A, Gu M, Wilson KD, Varadarajan A, Vadgama N, Balsubramani A, Wu JC, Engreitz JM, Farh K, Karakikes I, Wang KC, Quertermous T, Greenleaf WJ, Kundaje A | Cell | 36563664 | Cell | 2022 Dec 22 | https://www.ncbi.nlm.nih.gov/pubmed/36563664 |
Integrating regulatory DNA sequence and gene expression to predict genome-wide chromatin accessibility across cellular contexts. | Nair S, Kim DS, Perricone J, Kundaje A | Bioinformatics (Oxford, England) | 31510655 | Bioinformatics | 2019 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/31510655 |
Accelerating in silico saturation mutagenesis using compressed sensing. | Schreiber J, Nair S, Balsubramani A, Kundaje A | Bioinformatics (Oxford, England) | 35678521 | Bioinformatics | 2022 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/35678521 |
NETWORK MODELLING OF TOPOLOGICAL DOMAINS USING HI-C DATA. | Wang YXR, Sarkar P, Ursu O, Kundaje A, Bickel PJ | The annals of applied statistics | 32968472 | Ann Appl Stat | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32968472 |
Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin. | Yang D, Denny SK, Greenside PG, Chaikovsky AC, Brady JJ, Ouadah Y, Granja JM, Jahchan NS, Lim JS, Kwok S, Kong CS, Berghoff AS, Schmitt A, Reinhardt HC, Park KS, Preusser M, Kundaje A, Greenleaf WJ, Sage J, Winslow MM | Cancer discovery | 30228179 | Cancer Discov | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30228179 |
Opportunities and challenges for transcriptome-wide association studies. | Wainberg M, Sinnott-Armstrong N, Mancuso N, Barbeira AN, Knowles DA, Golan D, Ermel R, Ruusalepp A, Quertermous T, Hao K, Björkegren JLM, Im HK, Pasaniuc B, Rivas MA, Kundaje A | Nature genetics | 30926968 | Nat Genet | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30926968 |
Brief Report: Cell Cycle Dynamics of Human Pluripotent Stem Cells Primed for Differentiation. | Shcherbina A, Li J, Narayanan C, Greenleaf W, Kundaje A, Chetty S | Stem cells (Dayton, Ohio) | 31135093 | Stem Cells | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31135093 |
The Kipoi repository accelerates community exchange and reuse of predictive models for genomics. | Avsec Ž, Kreuzhuber R, Israeli J, Xu N, Cheng J, Shrikumar A, Banerjee A, Kim DS, Beier T, Urban L, Kundaje A, Stegle O, Gagneur J | Nature biotechnology | 31138913 | Nat Biotechnol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31138913 |
ChIP-ping the branches of the tree: functional genomics and the evolution of eukaryotic gene regulation. | Marinov GK, Kundaje A | Briefings in functional genomics | 29529131 | Brief Funct Genomics | 2018 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/29529131 |
Opportunities and obstacles for deep learning in biology and medicine. | Ching T, Himmelstein DS, Beaulieu-Jones BK, Kalinin AA, Do BT, Way GP, Ferrero E, Agapow PM, Zietz M, Hoffman MM, Xie W, Rosen GL, Lengerich BJ, Israeli J, Lanchantin J, Woloszynek S, Carpenter AE, Shrikumar A, Xu J, Cofer EM, Lavender CA, Turaga SC, Alexandari AM, Lu Z, Harris DJ, DeCaprio D, Qi Y, Kundaje A, Peng Y, Wiley LK, Segler MHS, Boca SM, Swamidass SJ, Huang A, Gitter A, Greene CS | Journal of the Royal Society, Interface | 29618526 | J R Soc Interface | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29618526 |
Prediction of protein-ligand interactions from paired protein sequence motifs and ligand substructures. | Greenside P, Hillenmeyer M, Kundaje A | Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing | 29218866 | Pac Symp Biocomput | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29218866 |
Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. | Kennedy DR, Lemiere J, Tan C, Simental E, Braxton J, Maxwell RA, Amine AA, Al-Sady B | bioRxiv : the preprint server for biology | 39554105 | bioRxiv | 2024 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/39554105 |
Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability. | Greenstein RA, Barrales RR, Sanchez NA, Bisanz JE, Braun S, Al-Sady B | Genes & development | 31805521 | Genes Dev | 2020 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/31805521 |
Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability. | Greenstein RA, Jones SK, Spivey EC, Rybarski JR, Finkelstein IJ, Al-Sady B | eLife | 30020075 | Elife | 2018 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/30020075 |
Epigenetic fates of gene silencing established by heterochromatin spreading in cell identity and genome stability. | Greenstein RA, Al-Sady B | Current genetics | 30390097 | Curr Genet | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30390097 |
Heterodimerization of H3K9 histone methyltransferases G9a and GLP activates methyl reading and writing capabilities. | Sanchez NA, Kallweit LM, Trnka MJ, Clemmer CL, Al-Sady B | The Journal of biological chemistry | 34619147 | J Biol Chem | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34619147 |
Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction. | Greenstein RA, Ng H, Barrales RR, Tan C, Braun S, Al-Sady B | PLoS genetics | 35584134 | PLoS Genet | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35584134 |
The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states. | Murawska M, Greenstein RA, Schauer T, Olsen KCF, Ng H, Ladurner AG, Al-Sady B, Braun S | Cell reports | 34731638 | Cell Rep | 2021 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/34731638 |
The complete structure of the small-subunit processome. | Barandun J, Chaker-Margot M, Hunziker M, Molloy KR, Chait BT, Klinge S | Nature structural & molecular biology | 28945246 | Nat Struct Mol Biol | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28945246 |
Ribosome assembly coming into focus. | Klinge S, Woolford JL Jr | Nature reviews. Molecular cell biology | 30467428 | Nat Rev Mol Cell Biol | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30467428 |
Conformational switches control early maturation of the eukaryotic small ribosomal subunit. | Hunziker M, Barandun J, Buzovetsky O, Steckler C, Molina H, Klinge S | eLife | 31206356 | Elife | 2019 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/31206356 |
Assembly and early maturation of large subunit precursors. | Chaker-Margot M, Klinge S | RNA (New York, N.Y.) | 30670483 | RNA | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30670483 |
Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome. | Barandun J, Hunziker M, Vossbrinck CR, Klinge S | Nature microbiology | 31332387 | Nat Microbiol | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31332387 |
Nucleolar maturation of the human small subunit processome. | Singh S, Vanden Broeck A, Miller L, Chaker-Margot M, Klinge S | Science (New York, N.Y.) | 34516797 | Science | 2021 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/34516797 |
Assembly and structure of the SSU processome-a nucleolar precursor of the small ribosomal subunit. | Barandun J, Hunziker M, Klinge S | Current opinion in structural biology | 29414516 | Curr Opin Struct Biol | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29414516 |
Modular assembly of the nucleolar pre-60S ribosomal subunit. | Sanghai ZA, Miller L, Molloy KR, Barandun J, Hunziker M, Chaker-Margot M, Wang J, Chait BT, Klinge S | Nature | 29512650 | Nature | 2018 Apr 5 | https://www.ncbi.nlm.nih.gov/pubmed/29512650 |
High Throughput Viability Assay for Microbiology. | Meyer CT, Lynch GK, Stamo DF, Miller EJ, Chatterjee A, Kralj JM | bioRxiv : the preprint server for biology | 36712102 | bioRxiv | 2023 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/36712102 |
Machine Learning Establishes Single-Cell Calcium Dynamics as an Early Indicator of Antibiotic Response. | Meyer CT, Jewell MP, Miller EJ, Kralj JM | Microorganisms | 34063175 | Microorganisms | 2021 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/34063175 |
Genome-Wide Functional Screen for Calcium Transients in Escherichia coli Identifies Increased Membrane Potential Adaptation to Persistent DNA Damage. | Luder R, Bruni GN, Kralj JM | Journal of bacteriology | 33199283 | J Bacteriol | 2021 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/33199283 |
A high-throughput and low-waste viability assay for microbes. | Meyer CT, Lynch GK, Stamo DF, Miller EJ, Chatterjee A, Kralj JM | Nature microbiology | 37919425 | Nat Microbiol | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/37919425 |
Live Cell Imaging Reveals pH Oscillations in Saccharomyces cerevisiae During Metabolic Transitions. | Dodd BJT, Kralj JM | Scientific reports | 29066766 | Sci Rep | 2017 Oct 24 | https://www.ncbi.nlm.nih.gov/pubmed/29066766 |
Finding the Spark. | Kralj JM | Bioelectricity | 34476390 | Bioelectricity | 2021 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/34476390 |
Membrane voltage dysregulation driven by metabolic dysfunction underlies bactericidal activity of aminoglycosides. | Bruni GN, Kralj JM | eLife | 32748785 | Elife | 2020 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/32748785 |
Voltage-gated calcium flux mediates Escherichia coli mechanosensation. | Bruni GN, Weekley RA, Dodd BJT, Kralj JM | Proceedings of the National Academy of Sciences of the United States of America | 28808010 | Proc Natl Acad Sci U S A | 2017 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/28808010 |
High throughput sequencing of in vitro selections of mRNA-displayed peptides: data analysis and applications. | Blanco C , Verbanic S , Seelig B , Chen IA | Physical chemistry chemical physics : PCCP | 31967131 | Phys Chem Chem Phys | 2020 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/31967131 |
Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages. | Peng H, Borg RE, Dow LP, Pruitt BL, Chen IA | Proceedings of the National Academy of Sciences of the United States of America | 31932441 | Proc Natl Acad Sci U S A | 2020 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/31932441 |
Promiscuous Ribozymes and Their Proposed Role in Prebiotic Evolution. | Janzen E, Blanco C, Peng H, Kenchel J, Chen IA | Chemical reviews | 32011135 | Chem Rev | 2020 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/32011135 |
Phage engineering and the evolutionary arms race. | Peng H, Chen IA | Current opinion in biotechnology | 33113495 | Curr Opin Biotechnol | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33113495 |
Improved single-swab sample preparation for recovering bacterial and phage DNA from human skin and wound microbiomes. | Verbanic S, Kim CY, Deacon JM, Chen IA | BMC microbiology | 31488062 | BMC Microbiol | 2019 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/31488062 |
Chimeric Phage Nanoparticles for Rapid Characterization of Bacterial Pathogens: Detection in Complex Biological Samples and Determination of Antibiotic Sensitivity. | Peng H, Borg RE, Nguyen ABN, Chen IA | ACS sensors | 32314570 | ACS Sens | 2020 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/32314570 |
Kinetic sequencing (k-Seq) as a massively parallel assay for ribozyme kinetics: utility and critical parameters. | Shen Y, Pressman A, Janzen E, Chen IA | Nucleic acids research | 33772580 | Nucleic Acids Res | 2021 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/33772580 |
PacBio sequencing output increased through uniform and directional fivefold concatenation. | Kanwar N, Blanco C, Chen IA, Seelig B | Scientific reports | 34508117 | Sci Rep | 2021 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/34508117 |
Rapid Colorimetric Detection of Bacterial Species through the Capture of Gold Nanoparticles by Chimeric Phages. | Peng H, Chen IA | ACS nano | 30586498 | ACS Nano | 2019 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/30586498 |
Genetically engineered filamentous phage for bacterial detection using magnetic resonance imaging. | Borg RE, Ozbakir HF, Xu B, Li E, Fang X, Peng H, Chen IA, Mukherjee A | Sensors & diagnostics | 38405385 | Sens Diagn | 2023 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/38405385 |
Phage therapy administered noninvasively could be effective in thin tubes subject to episodic flow despite washout: a simulation study. | Blanco C, Chen IA | Physical biology | 31266001 | Phys Biol | 2019 Jul 22 | https://www.ncbi.nlm.nih.gov/pubmed/31266001 |
Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds. | Verbanic S, Shen Y, Lee J, Deacon JM, Chen IA | NPJ biofilms and microbiomes | 32358500 | NPJ Biofilms Microbiomes | 2020 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/32358500 |
Treatment of Wound Infections in a Mouse Model Using Zn(2+)-Releasing Phage Bound to Gold Nanorods. | Peng H, Rossetto D, Mansy SS, Jordan MC, Roos KP, Chen IA | ACS nano | 35239330 | ACS Nano | 2022 Mar 22 | https://www.ncbi.nlm.nih.gov/pubmed/35239330 |
Emergent properties as by-products of prebiotic evolution of aminoacylation ribozymes. | Janzen E, Shen Y, Vázquez-Salazar A, Liu Z, Blanco C, Kenchel J, Chen IA | Nature communications | 35752631 | Nat Commun | 2022 Jun 25 | https://www.ncbi.nlm.nih.gov/pubmed/35752631 |
Modulation of α-Synuclein Aggregation In Vitro by a DNA Aptamer. | Tran CH, Saha R, Blanco C, Bagchi D, Chen IA | Biochemistry | 35994742 | Biochemistry | 2022 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/35994742 |
Preparation of Bioconjugates of Chimeric M13 Phage and Gold Nanorods. | Peng H, Chen IA | Methods in molecular biology (Clifton, N.J.) | 38526728 | Methods Mol Biol | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38526728 |
The Chronic Wound Phageome: Phage Diversity and Associations with Wounds and Healing Outcomes. | Verbanic S, Deacon JM, Chen IA | Microbiology spectrum | 35435739 | Microbiol Spectr | 2022 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/35435739 |
EasyDIVER: A Pipeline for Assembling and Counting High-Throughput Sequencing Data from In Vitro Evolution of Nucleic Acids or Peptides. | Blanco C, Verbanic S, Seelig B, Chen IA | Journal of molecular evolution | 32529275 | J Mol Evol | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32529275 |
Effects of Preservation and Propagation Methodology on Microcosms Derived from the Oral Microbiome. | Zhou B, Mobberley J, Shi K, Chen IA | Microorganisms | 36363738 | Microorganisms | 2022 Oct 29 | https://www.ncbi.nlm.nih.gov/pubmed/36363738 |
Self-cleaving ribozymes: substrate specificity and synthetic biology applications. | Peng H, Latifi B, Müller S, Lupták A, Chen IA | RSC chemical biology | 34704043 | RSC Chem Biol | 2021 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/34704043 |
Vesicle encapsulation stabilizes intermolecular association and structure formation of functional RNA and DNA. | Peng H, Lelievre A, Landenfeld K, Müller S, Chen IA | Current biology : CB | 34762821 | Curr Biol | 2022 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/34762821 |
A Bayesian nonparametric analysis for zero-inflated multivariate count data with application to microbiome study. | Shuler K, Verbanic S, Chen IA, Lee J | Journal of the Royal Statistical Society. Series C, Applied statistics | 37440868 | J R Stat Soc Ser C Appl Stat | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37440868 |
Visualization of Engineered M13 Phages Bound to Bacterial Targets by Transmission Electron Microscopy. | Yang Y, Chen IA | Methods in molecular biology (Clifton, N.J.) | 38526731 | Methods Mol Biol | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/38526731 |
Pharmacokinetics and Biodistribution of Phages and their Current Applications in Antimicrobial Therapy. | Kang D, Bagchi D, Chen IA | Advanced therapeutics | 38933919 | Adv Ther (Weinh) | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38933919 |
Single-cell analyses to tailor treatments. | Shalek AK, Benson M | Science translational medicine | 28931656 | Sci Transl Med | 2017 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/28931656 |
Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus. | Sangesland M, Ronsard L, Kazer SW, Bals J, Boyoglu-Barnum S, Yousif AS, Barnes R, Feldman J, Quirindongo-Crespo M, McTamney PM, Rohrer D, Lonberg N, Chackerian B, Graham BS, Kanekiyo M, Shalek AK, Lingwood D | Immunity | 31563464 | Immunity | 2019 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/31563464 |
Identification of a Master Regulator of Differentiation in Toxoplasma. | Waldman BS, Schwarz D, Wadsworth MH 2nd, Saeij JP, Shalek AK, Lourido S | Cell | 31955846 | Cell | 2020 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/31955846 |
Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity. | Burbage M, Gasparrini F, Aggarwal S, Gaya M, Arnold J, Nair U, Way M, Bruckbauer A, Batista FD | eLife | 29337666 | Elife | 2018 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/29337666 |
Expression of Foxp3 by T follicular helper cells in end-stage germinal centers. | Jacobsen JT, Hu W, R Castro TB, Solem S, Galante A, Lin Z, Allon SJ, Mesin L, Bilate AM, Schiepers A, Shalek AK, Rudensky AY, Victora GD | Science (New York, N.Y.) | 34437125 | Science | 2021 Jul 16 | https://www.ncbi.nlm.nih.gov/pubmed/34437125 |
Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity. | Zhivaki D, Borriello F, Chow OA, Doran B, Fleming I, Theisen DJ, Pallis P, Shalek AK, Sokol CL, Zanoni I, Kagan JC | Cell reports | 33207188 | Cell Rep | 2020 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/33207188 |
Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis. | Corleis B, Tzouanas CN, Wadsworth MH 2nd, Cho JL, Linder AH, Schiff AE, Zessin B, Stei F, Dorhoi A, Dickey AK, Medoff BD, Shalek AK, Kwon DS | Science translational medicine | 38055798 | Sci Transl Med | 2023 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/38055798 |
Allergic inflammatory memory in human respiratory epithelial progenitor cells. | Ordovas-Montanes J, Dwyer DF, Nyquist SK, Buchheit KM, Vukovic M, Deb C, Wadsworth MH 2nd, Hughes TK, Kazer SW, Yoshimoto E, Cahill KN, Bhattacharyya N, Katz HR, Berger B, Laidlaw TM, Boyce JA, Barrett NA, Shalek AK | Nature | 30135581 | Nature | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30135581 |
Seq-Well: A Sample-Efficient, Portable Picowell Platform for Massively Parallel Single-Cell RNA Sequencing. | Aicher TP, Carroll S, Raddi G, Gierahn T, Wadsworth MH 2nd, Hughes TK, Love C, Shalek AK | Methods in molecular biology (Clifton, N.J.) | 31028635 | Methods Mol Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31028635 |
Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer. | Hamza B, Ng SR, Prakadan SM, Delgado FF, Chin CR, King EM, Yang LF, Davidson SM, DeGouveia KL, Cermak N, Navia AW, Winter PS, Drake RS, Tammela T, Li CM, Papagiannakopoulos T, Gupta AJ, Shaw Bagnall J, Knudsen SM, Vander Heiden MG, Wasserman SC, Jacks T, Shalek AK, Manalis SR | Proceedings of the National Academy of Sciences of the United States of America | 30674677 | Proc Natl Acad Sci U S A | 2019 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/30674677 |
TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures. | Tu AA, Gierahn TM, Monian B, Morgan DM, Mehta NK, Ruiter B, Shreffler WG, Shalek AK, Love JC | Nature immunology | 31745340 | Nat Immunol | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31745340 |
Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice. | Hamza B, Miller AB, Meier L, Stockslager M, Ng SR, King EM, Lin L, DeGouveia KL, Mulugeta N, Calistri NL, Strouf H, Bray C, Rodriguez F, Freed-Pastor WA, Chin CR, Jaramillo GC, Burger ML, Weinberg RA, Shalek AK, Jacks T, Manalis SR | Nature communications | 34584084 | Nat Commun | 2021 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/34584084 |
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages. | Kimmerling RJ, Lee Szeto G, Li JW, Genshaft AS, Kazer SW, Payer KR, de Riba Borrajo J, Blainey PC, Irvine DJ, Shalek AK, Manalis SR | Nature communications | 26732280 | Nat Commun | 2016 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/26732280 |
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq. | Tirosh I, Izar B, Prakadan SM, Wadsworth MH 2nd, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, Lu D, Genshaft AS, Hughes TK, Ziegler CG, Kazer SW, Gaillard A, Kolb KE, Villani AC, Johannessen CM, Andreev AY, Van Allen EM, Bertagnolli M, Sorger PK, Sullivan RJ, Flaherty KT, Frederick DT, Jané-Valbuena J, Yoon CH, Rozenblatt-Rosen O, Shalek AK, Regev A, Garraway LA | Science (New York, N.Y.) | 27124452 | Science | 2016 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/27124452 |
Circulating CXCR5(+)CXCR3(+)PD-1(lo) Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth. | Martin-Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb KE, Schulze Zur Wiesch J, Cubas R, Porichis F, Shalek AK, van Lunzen J, Haddad EK, Walker BD, Kaufmann DE, Lichterfeld M, Yu XG | JCI insight | 28138558 | JCI Insight | 2017 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/28138558 |
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation. | Mead BE, Hattori K, Levy L, Imada S, Goto N, Vukovic M, Sze D, Kummerlowe C, Matute JD, Duan J, Langer R, Blumberg RS, Ordovas-Montanes J, Yilmaz ÖH, Karp JM, Shalek AK | Nature biomedical engineering | 35314801 | Nat Biomed Eng | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35314801 |
A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers. | Martin-Gayo E, Cole MB, Kolb KE, Ouyang Z, Cronin J, Kazer SW, Ordovas-Montanes J, Lichterfeld M, Walker BD, Yosef N, Shalek AK, Yu XG | Genome biology | 29378643 | Genome Biol | 2018 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/29378643 |
Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput. | Gierahn TM, Wadsworth MH 2nd, Hughes TK, Bryson BD, Butler A, Satija R, Fortune S, Love JC, Shalek AK | Nature methods | 28192419 | Nat Methods | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/28192419 |
Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion. | Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, Crawford F, White J, Montoya A, Power K, Allen TM, Streeck H, Kaufmann DE, Picker LJ, Kappler JW, Walker BD | Immunity | 27760342 | Immunity | 2016 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/27760342 |
Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction. | Genshaft AS, Li S, Gallant CJ, Darmanis S, Prakadan SM, Ziegler CG, Lundberg M, Fredriksson S, Hong J, Regev A, Livak KJ, Landegren U, Shalek AK | Genome biology | 27640647 | Genome Biol | 2016 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/27640647 |
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment. | Nirschl CJ, Suárez-Fariñas M, Izar B, Prakadan S, Dannenfelser R, Tirosh I, Liu Y, Zhu Q, Devi KSP, Carroll SL, Chau D, Rezaee M, Kim TG, Huang R, Fuentes-Duculan J, Song-Zhao GX, Gulati N, Lowes MA, King SL, Quintana FJ, Lee YS, Krueger JG, Sarin KY, Yoon CH, Garraway L, Regev A, Shalek AK, Troyanskaya O, Anandasabapathy N | Cell | 28666115 | Cell | 2017 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/28666115 |
Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents. | Lossos C, Liu Y, Kolb KE, Christie AL, Van Scoyk A, Prakadan SM, Shigemori K, Stevenson KE, Morrow S, Plana OD, Fraser C, Jones KL, Liu H, Pallasch CP, Modiste R, Nguyen QD, Craig JW, Morgan EA, Vega F, Aster JC, Sarosiek KA, Shalek AK, Hemann MT, Weinstock DM | Cancer discovery | 31040105 | Cancer Discov | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31040105 |
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. | Pepe-Mooney BJ, Dill MT, Alemany A, Ordovas-Montanes J, Matsushita Y, Rao A, Sen A, Miyazaki M, Anakk S, Dawson PA, Ono N, Shalek AK, van Oudenaarden A, Camargo FD | Cell stem cell | 31080134 | Cell Stem Cell | 2019 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/31080134 |
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases. | Gawel DR, Serra-Musach J, Lilja S, Aagesen J, Arenas A, Asking B, Bengnér M, Björkander J, Biggs S, Ernerudh J, Hjortswang H, Karlsson JE, Köpsen M, Lee EJ, Lentini A, Li X, Magnusson M, Martínez-Enguita D, Matussek A, Nestor CE, Schäfer S, Seifert O, Sonmez C, Stjernman H, Tjärnberg A, Wu S, Åkesson K, Shalek AK, Stenmarker M, Zhang H, Gustafsson M, Benson M | Genome medicine | 31358043 | Genome Med | 2019 Jul 30 | https://www.ncbi.nlm.nih.gov/pubmed/31358043 |
Distribution and storage of inflammatory memory in barrier tissues. | Ordovas-Montanes J, Beyaz S, Rakoff-Nahoum S, Shalek AK | Nature reviews. Immunology | 32015472 | Nat Rev Immunol | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32015472 |
A Single Human V(H)-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood. | Sangesland M, Yousif AS, Ronsard L, Kazer SW, Zhu AL, Gatter GJ, Hayward MR, Barnes RM, Quirindongo-Crespo M, Rohrer D, Lonberg N, Kwon D, Shalek AK, Lingwood D | Cell reports | 32846123 | Cell Rep | 2020 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/32846123 |
Scaling by shrinking: empowering single-cell 'omics' with microfluidic devices. | Prakadan SM, Shalek AK, Weitz DA | Nature reviews. Genetics | 28392571 | Nat Rev Genet | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28392571 |
Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. | Tsankov AM, Wadsworth MH 2nd, Akopian V, Charlton J, Allon SJ, Arczewska A, Mead BE, Drake RS, Smith ZD, Mikkelsen TS, Shalek AK, Meissner A | Development (Cambridge, England) | 31515224 | Development | 2019 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/31515224 |
Linking single-cell measurements of mass, growth rate, and gene expression. | Kimmerling RJ, Prakadan SM, Gupta AJ, Calistri NL, Stevens MM, Olcum S, Cermak N, Drake RS, Pelton K, De Smet F, Ligon KL, Shalek AK, Manalis SR | Genome biology | 30482222 | Genome Biol | 2018 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/30482222 |
Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes. | Genshaft AS, Ziegler CGK, Tzouanas CN, Mead BE, Jaeger AM, Navia AW, King RP, Mana MD, Huang S, Mitsialis V, Snapper SB, Yilmaz ÖH, Jacks T, Van Humbeck JF, Shalek AK | Nature communications | 34404785 | Nat Commun | 2021 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/34404785 |
Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells. | Pae J, Ersching J, Castro TBR, Schips M, Mesin L, Allon SJ, Ordovas-Montanes J, Mlynarczyk C, Melnick A, Efeyan A, Shalek AK, Meyer-Hermann M, Victora GD | The Journal of experimental medicine | 33332554 | J Exp Med | 2021 Apr 5 | https://www.ncbi.nlm.nih.gov/pubmed/33332554 |
Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential. | Huang S, Ziegler CGK, Austin J, Mannoun N, Vukovic M, Ordovas-Montanes J, Shalek AK, von Andrian UH | Cell | 33333021 | Cell | 2021 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/33333021 |
Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies. | Sanjuan Nandin I, Fong C, Deantonio C, Torreno-Pina JA, Pecetta S, Maldonado P, Gasparrini F, Ordovas-Montanes J, Kazer SW, Kjaer S, Borley DW, Nair U, Coleman JA, Lingwood D, Shalek AK, Meffre E, Poignard P, Burton DR, Batista FD | The Journal of experimental medicine | 28739603 | J Exp Med | 2017 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/28739603 |
PI3Kβ controls immune evasion in PTEN-deficient breast tumours. | Bergholz JS, Wang Q, Wang Q, Ramseier M, Prakadan S, Wang W, Fang R, Kabraji S, Zhou Q, Gray GK, Abell-Hart K, Xie S, Guo X, Gu H, Von T, Jiang T, Tang S, Freeman GJ, Kim HJ, Shalek AK, Roberts TM, Zhao JJ | Nature | 37076617 | Nature | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37076617 |
Distinct olfactory mucosal macrophage populations mediate neuronal maintenance and pathogen defense. | Wellford SA, Chen CW, Vukovic M, Batich KA, Lin E, Shalek AK, Ordovas-Montanes J, Moseman AP, Moseman EA | Mucosal immunology | 39074615 | Mucosal Immunol | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39074615 |
Increased lateral microtubule contact at the cell cortex is sufficient to drive mammalian spindle elongation. | Guild J, Ginzberg MB, Hueschen CL, Mitchison TJ, Dumont S | Molecular biology of the cell | 28468979 | Mol Biol Cell | 2017 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/28468979 |
Microtubule End-Clustering Maintains a Steady-State Spindle Shape. | Hueschen CL, Galstyan V, Amouzgar M, Phillips R, Dumont S | Current biology : CB | 30744975 | Curr Biol | 2019 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/30744975 |
The Spindle: Integrating Architecture and Mechanics across Scales. | Elting MW, Suresh P, Dumont S | Trends in cell biology | 30093097 | Trends Cell Biol | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30093097 |
Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner. | Kuhn J, Dumont S | The Journal of cell biology | 31492713 | J Cell Biol | 2019 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/31492713 |
The Astrin-SKAP complex reduces friction at the kinetochore-microtubule interface. | Rosas-Salvans M, Sutanto R, Suresh P, Dumont S | Current biology : CB | 35580605 | Curr Biol | 2022 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/35580605 |
Hec1 Tail Phosphorylation Differentially Regulates Mammalian Kinetochore Coupling to Polymerizing and Depolymerizing Microtubules. | Long AF, Udy DB, Dumont S | Current biology : CB | 28552353 | Curr Biol | 2017 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/28552353 |
MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities. | Rohrberg J, Van de Mark D, Amouzgar M, Lee JV, Taileb M, Corella A, Kilinc S, Williams J, Jokisch ML, Camarda R, Balakrishnan S, Shankar R, Zhou A, Chang AN, Chen B, Rugo HS, Dumont S, Goga A | Cell reports | 32160543 | Cell Rep | 2020 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/32160543 |
Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes. | Suresh P, Long AF, Dumont S | eLife | 32191206 | Elife | 2020 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/32191206 |
The mammalian kinetochore-microtubule interface: robust mechanics and computation with many microtubules. | Long AF, Kuhn J, Dumont S | Current opinion in cell biology | 31132675 | Curr Opin Cell Biol | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31132675 |
The chromokinesin Klp3a and microtubules facilitate acentric chromosome segregation. | Karg T, Elting MW, Vicars H, Dumont S, Sullivan W | The Journal of cell biology | 28500183 | J Cell Biol | 2017 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/28500183 |
NuMA recruits dynein activity to microtubule minus-ends at mitosis. | Hueschen CL, Kenny SJ, Xu K, Dumont S | eLife | 29185983 | Elife | 2017 Nov 29 | https://www.ncbi.nlm.nih.gov/pubmed/29185983 |
Spindle assembly checkpoint satisfaction occurs via end-on but not lateral attachments under tension. | Kuhn J, Dumont S | The Journal of cell biology | 28536121 | J Cell Biol | 2017 Jun 5 | https://www.ncbi.nlm.nih.gov/pubmed/28536121 |
Opposing motors provide mechanical and functional robustness in the human spindle. | Neahring L, Cho NH, Dumont S | Developmental cell | 34614397 | Dev Cell | 2021 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/34614397 |
Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure. | Long AF, Suresh P, Dumont S | The Journal of cell biology | 32435797 | J Cell Biol | 2020 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/32435797 |
Mapping Load-Bearing in the Mammalian Spindle Reveals Local Kinetochore Fiber Anchorage that Provides Mechanical Isolation and Redundancy. | Elting MW, Prakash M, Udy DB, Dumont S | Current biology : CB | 28690110 | Curr Biol | 2017 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/28690110 |
The mitotic protein NuMA plays a spindle-independent role in nuclear formation and mechanics. | Serra-Marques A, Houtekamer R, Hintzen D, Canty JT, Yildiz A, Dumont S | The Journal of cell biology | 33044554 | J Cell Biol | 2020 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/33044554 |
Progress and challenges for chemical probing of RNA structure inside living cells. | Kubota M, Tran C, Spitale RC | Nature chemical biology | 26575240 | Nat Chem Biol | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26575240 |
Metabolic Incorporation of Azide Functionality into Cellular RNA. | Nainar S, Beasley S, Fazio M, Kubota M, Dai N, Corrêa IR Jr, Spitale RC | Chembiochem : a European journal of chemical biology | 27595557 | Chembiochem | 2016 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/27595557 |
Comparative Analysis Reveals Furoyl in Vivo Selective Hydroxyl Acylation Analyzed by Primer Extension Reagents Form Stable Ribosyl Ester Adducts. | Chan D, Feng C, Zhen Y, Flynn RA, Spitale RC | Biochemistry | 28319368 | Biochemistry | 2017 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/28319368 |
Bioorthogonal Metabolic Labeling of Nascent RNA in Neurons Improves the Sensitivity of Transcriptome-Wide Profiling. | Zajaczkowski EL, Zhao QY, Zhang ZH, Li X, Wei W, Marshall PR, Leighton LJ, Nainar S, Feng C, Spitale RC, Bredy TW | ACS chemical neuroscience | 29874042 | ACS Chem Neurosci | 2018 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/29874042 |
Biochemical Methods To Image and Analyze RNA Localization: From One to Many. | Li Y, Ke K, Spitale RC | Biochemistry | 30444114 | Biochemistry | 2019 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/30444114 |
Human iPSC-derived microglia: A growing toolset to study the brain's innate immune cells. | Hasselmann J, Blurton-Jones M | Glia | 31926038 | Glia | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31926038 |
Chemical Tools for Dissecting the Role of lncRNAs in Epigenetic Regulation. | Nainar S, Feng C, Spitale RC | ACS chemical biology | 27267401 | ACS Chem Biol | 2016 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/27267401 |
Facile synthesis and evaluation of a dual-functioning furoyl probe for in-cell SHAPE. | Chan D, Beasley S, Zhen Y, Spitale RC | Bioorganic & medicinal chemistry letters | 29398542 | Bioorg Med Chem Lett | 2018 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/29398542 |
Assaying RNA Structure Inside Living Cells with SHAPE. | Feng C, Chan D, Spitale RC | Methods in molecular biology (Clifton, N.J.) | 28766302 | Methods Mol Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28766302 |
Multiplex Aptamer Discovery through Apta-Seq and Its Application to ATP Aptamers Derived from Human-Genomic SELEX. | Abdelsayed MM, Ho BT, Vu MMK, Polanco J, Spitale RC, Lupták A | ACS chemical biology | 28661647 | ACS Chem Biol | 2017 Aug 18 | https://www.ncbi.nlm.nih.gov/pubmed/28661647 |
Halo-seq: An RNA Proximity Labeling Method for the Isolation and Analysis of Subcellular RNA Populations. | Lo HG, Engel KL, Goering R, Li Y, Spitale RC, Taliaferro JM | Current protocols | 35532287 | Curr Protoc | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35532287 |
Light-activated chemical probing of nucleobase solvent accessibility inside cells. | Feng C, Chan D, Joseph J, Muuronen M, Coldren WH, Dai N, Corrêa IR Jr, Furche F, Hadad CM, Spitale RC | Nature chemical biology | 29334380 | Nat Chem Biol | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29334380 |
Identification of Adenosine-to-Inosine RNA Editing with Acrylonitrile Reagents. | Li Y, Göhl M, Ke K, Vanderwal CD, Spitale RC | Organic letters | 31516001 | Org Lett | 2019 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/31516001 |
Evolving insights into RNA modifications and their functional diversity in the brain. | Nainar S, Marshall PR, Tyler CR, Spitale RC, Bredy TW | Nature neuroscience | 27669990 | Nat Neurosci | 2016 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/27669990 |
Cycloaddition enabled mutational profiling of 5-vinyluridine in RNA. | Gupta M, Wang J, Garfio CM, Vandewalle A, Spitale RC | Chemical communications (Cambridge, England) | 36815680 | Chem Commun (Camb) | 2023 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/36815680 |
A Bump-Hole Strategy for Increased Stringency of Cell-Specific Metabolic Labeling of RNA. | Nguyen K, Kubota M, Arco JD, Feng C, Singha M, Beasley S, Sakr J, Gandhi SP, Blurton-Jones M, Fernández Lucas J, Spitale RC | ACS chemical biology | 33222436 | ACS Chem Biol | 2020 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/33222436 |
Expanding the Scope of RNA Metabolic Labeling with Vinyl Nucleosides and Inverse Electron-Demand Diels-Alder Chemistry. | Kubota M, Nainar S, Parker SM, England W, Furche F, Spitale RC | ACS chemical biology | 31310712 | ACS Chem Biol | 2019 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/31310712 |
Improved Analysis of RNA Localization by Spatially Restricted Oxidation of RNA-Protein Complexes. | Li Y, Aggarwal MB, Ke K, Nguyen K, Spitale RC | Biochemistry | 29474061 | Biochemistry | 2018 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/29474061 |
Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. | Hasselmann J, Coburn MA, England W, Figueroa Velez DX, Kiani Shabestari S, Tu CH, McQuade A, Kolahdouzan M, Echeverria K, Claes C, Nakayama T, Azevedo R, Coufal NG, Han CZ, Cummings BJ, Davtyan H, Glass CK, Healy LM, Gandhi SP, Spitale RC, Blurton-Jones M | Neuron | 31375314 | Neuron | 2019 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/31375314 |
Photo-controlled cell-specific metabolic labeling of RNA. | Feng C, Li Y, Spitale RC | Organic & biomolecular chemistry | 28569333 | Org Biomol Chem | 2017 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/28569333 |
Measuring RNA structure transcriptome-wide with icSHAPE. | Chan D, Feng C, Spitale RC | Methods (San Diego, Calif.) | 28336307 | Methods | 2017 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/28336307 |
Spatially Restricting Bioorthogonal Nucleoside Biosynthesis Enables Selective Metabolic Labeling of the Mitochondrial Transcriptome. | Nguyen K, Aggarwal MB, Feng C, Balderrama G, Fazio M, Mortazavi A, Spitale RC | ACS chemical biology | 29756767 | ACS Chem Biol | 2018 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/29756767 |
Defining Functional Structured RNA inside Living Cells. | Chan D, Spitale RC | Biochemistry | 29064690 | Biochemistry | 2017 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/29064690 |
Protected pyrimidine nucleosides for cell-specific metabolic labeling of RNA. | Beasley S, Nguyen K, Fazio M, Spitale RC | Tetrahedron letters | 31031425 | Tetrahedron Lett | 2018 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/31031425 |
Assaying RNA Localization in Situ with Spatially Restricted Nucleobase Oxidation. | Li Y, Aggarwal MB, Nguyen K, Ke K, Spitale RC | ACS chemical biology | 28952711 | ACS Chem Biol | 2017 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/28952711 |
Assaying RNA solvent accessibility in living cells with LASER. | Feng C, Spitale RC | Methods in enzymology | 32713532 | Methods Enzymol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32713532 |
Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq. | Engel KL, Lo HG, Goering R, Li Y, Spitale RC, Taliaferro JM | Nucleic acids research | 34875090 | Nucleic Acids Res | 2022 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/34875090 |
Scalable, Continuous Evolution of Genes at Mutation Rates above Genomic Error Thresholds. | Ravikumar A, Arzumanyan GA, Obadi MKA, Javanpour AA, Liu CC | Cell | 30415839 | Cell | 2018 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/30415839 |
Lineage tracing and analog recording in mammalian cells by single-site DNA writing. | Loveless TB, Grotts JH, Schechter MW, Forouzmand E, Carlson CK, Agahi BS, Liang G, Ficht M, Liu B, Xie X, Liu CC | Nature chemical biology | 33753928 | Nat Chem Biol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33753928 |
Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities. | Rix G, Watkins-Dulaney EJ, Almhjell PJ, Boville CE, Arnold FH, Liu CC | Nature communications | 33159067 | Nat Commun | 2020 Nov 6 | https://www.ncbi.nlm.nih.gov/pubmed/33159067 |
Evolving Small-Molecule Biosensors with Improved Performance and Reprogrammed Ligand Preference Using OrthoRep. | Javanpour AA, Liu CC | ACS synthetic biology | 34597502 | ACS Synth Biol | 2021 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/34597502 |
Synthetic Epigenetics To Engineer Regulation. | Loveless TB, Liu CC | Biochemistry | 30860818 | Biochemistry | 2019 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/30860818 |
Open-ended molecular recording of sequential cellular events into DNA. | Loveless TB, Carlson CK, Dentzel Helmy CA, Hu VJ, Ross SK, Demelo MC, Murtaza A, Liang G, Ficht M, Singhai A, Pajoh-Casco MJ, Liu CC | Nature chemical biology | 39543397 | Nat Chem Biol | 2025 Apr | https://www.ncbi.nlm.nih.gov/pubmed/39543397 |
Rapid generation of potent antibodies by autonomous hypermutation in yeast. | Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC | bioRxiv : the preprint server for biology | 33200136 | bioRxiv | 2020 Nov 11 | https://www.ncbi.nlm.nih.gov/pubmed/33200136 |
Tunable Expression Systems for Orthogonal DNA Replication. | Zhong Z, Ravikumar A, Liu CC | ACS synthetic biology | 30408954 | ACS Synth Biol | 2018 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/30408954 |
Genetic Compatibility and Extensibility of Orthogonal Replication. | Javanpour AA, Liu CC | ACS synthetic biology | 31095905 | ACS Synth Biol | 2019 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/31095905 |
Toward an orthogonal central dogma. | Liu CC, Jewett MC, Chin JW, Voigt CA | Nature chemical biology | 29337969 | Nat Chem Biol | 2018 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/29337969 |
Mutually Orthogonal DNA Replication Systems In Vivo. | Arzumanyan GA, Gabriel KN, Ravikumar A, Javanpour AA, Liu CC | ACS synthetic biology | 29969238 | ACS Synth Biol | 2018 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/29969238 |
Probing pathways of adaptation with continuous evolution. | Zhong Z, Liu CC | Current opinion in systems biology | 31608311 | Curr Opin Syst Biol | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31608311 |
Automated Continuous Evolution of Proteins in Vivo. | Zhong Z, Wong BG, Ravikumar A, Arzumanyan GA, Khalil AS, Liu CC | ACS synthetic biology | 32374988 | ACS Synth Biol | 2020 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/32374988 |
Rapid generation of potent antibodies by autonomous hypermutation in yeast. | Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC | Nature chemical biology | 34168368 | Nat Chem Biol | 2021 Oct | https://www.ncbi.nlm.nih.gov/pubmed/34168368 |
Genetic Engineering by DNA Recombineering. | Papa LJ 3rd, Shoulders MD | Current protocols in chemical biology | 31483098 | Curr Protoc Chem Biol | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31483098 |
Multidimensional chemical control of CRISPR-Cas9. | Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A | Nature chemical biology | 27820801 | Nat Chem Biol | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27820801 |
HSF1 Activation Can Restrict HIV Replication. | Nekongo EE, Ponomarenko AI, Dewal MB, Butty VL, Browne EP, Shoulders MD | ACS infectious diseases | 32502335 | ACS Infect Dis | 2020 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/32502335 |
A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo. | Moore CL, Papa LJ 3rd, Shoulders MD | Journal of the American Chemical Society | 29991261 | J Am Chem Soc | 2018 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/29991261 |
The Path of Least Resistance: Mechanisms to Reduce Influenza's Sensitivity to Oseltamivir. | Phillips AM, Shoulders MD | Journal of molecular biology | 26748011 | J Mol Biol | 2016 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/26748011 |
Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin. | Phillips AM, Doud MB, Gonzalez LO, Butty VL, Lin YS, Bloom JD, Shoulders MD | eLife | 30188321 | Elife | 2018 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/30188321 |
Transportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1. | Moore CL, Dewal MB, Nekongo EE, Santiago S, Lu NB, Levine SS, Shoulders MD | ACS chemical biology | 26502114 | ACS Chem Biol | 2016 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/26502114 |
Host proteostasis modulates influenza evolution. | Phillips AM, Gonzalez LO, Nekongo EE, Ponomarenko AI, McHugh SM, Butty VL, Levine SS, Lin YS, Mirny LA, Shoulders MD | eLife | 28949290 | Elife | 2017 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/28949290 |
Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones. | Phillips AM, Ponomarenko AI, Chen K, Ashenberg O, Miao J, McHugh SM, Butty VL, Whittaker CA, Moore CL, Bloom JD, Lin YS, Shoulders MD | PLoS biology | 30222731 | PLoS Biol | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30222731 |
An Adaptable Platform for Directed Evolution in Human Cells. | Berman CM, Papa LJ 3rd, Hendel SJ, Moore CL, Suen PH, Weickhardt AF, Doan ND, Kumar CM, Uil TG, Butty VL, Hoeben RC, Shoulders MD | Journal of the American Chemical Society | 30427676 | J Am Chem Soc | 2018 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/30427676 |
Chemical Biology Framework to Illuminate Proteostasis. | Sebastian RM, Shoulders MD | Annual review of biochemistry | 32097570 | Annu Rev Biochem | 2020 Jun 20 | https://www.ncbi.nlm.nih.gov/pubmed/32097570 |
A common bacterial metabolite elicits prion-based bypass of glucose repression. | Garcia DM, Dietrich D, Clardy J, Jarosz DF | eLife | 27906649 | Elife | 2016 Nov 29 | https://www.ncbi.nlm.nih.gov/pubmed/27906649 |
A prion accelerates proliferation at the expense of lifespan. | Garcia DM, Campbell EA, Jakobson CM, Tsuchiya M, Shaw EA, DiNardo AL, Kaeberlein M, Jarosz DF | eLife | 34545808 | Elife | 2021 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/34545808 |
Biomolecular Condensation: A New Phase in Cancer Research. | Chakravarty AK, McGrail DJ, Lozanoski TM, Dunn BS, Shih DJH, Cirillo KM, Cetinkaya SH, Zheng WJ, Mills GB, Yi SS, Jarosz DF, Sahni N | Cancer discovery | 35852417 | Cancer Discov | 2022 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/35852417 |
Massively parallel experimental interrogation of natural variants in ancient signaling pathways reveals both purifying selection and local adaptation. | Aguilar-Rodríguez J, Vila J, Chen SA, Razo-Mejia M, Ghosh O, Fraser HB, Jarosz DF, Petrov DA | bioRxiv : the preprint server for biology | 39553990 | bioRxiv | 2024 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/39553990 |
Organizing biochemistry in space and time using prion-like self-assembly. | Jakobson CM, Jarosz DF | Current opinion in systems biology | 29725624 | Curr Opin Syst Biol | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29725624 |
A Prion Epigenetic Switch Establishes an Active Chromatin State. | Harvey ZH, Chakravarty AK, Futia RA, Jarosz DF | Cell | 32109413 | Cell | 2020 Mar 5 | https://www.ncbi.nlm.nih.gov/pubmed/32109413 |
A Non-amyloid Prion Particle that Activates a Heritable Gene Expression Program. | Chakravarty AK, Smejkal T, Itakura AK, Garcia DM, Jarosz DF | Molecular cell | 31757755 | Mol Cell | 2020 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/31757755 |
What Has a Century of Quantitative Genetics Taught Us About Nature's Genetic Tool Kit? | Jakobson CM, Jarosz DF | Annual review of genetics | 32897739 | Annu Rev Genet | 2020 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/32897739 |
Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome. | She R, Chakravarty AK, Layton CJ, Chircus LM, Andreasson JO, Damaraju N, McMahon PL, Buenrostro JD, Jarosz DF, Greenleaf WJ | Proceedings of the National Academy of Sciences of the United States of America | 28325876 | Proc Natl Acad Sci U S A | 2017 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/28325876 |
Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits. | Chakrabortee S, Byers JS, Jones S, Garcia DM, Bhullar B, Chang A, She R, Lee L, Fremin B, Lindquist S, Jarosz DF | Cell | 27693355 | Cell | 2016 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/27693355 |
Tissue-specific landscape of protein aggregation and quality control in an aging vertebrate. | Chen YR, Harel I, Singh PP, Ziv I, Moses E, Goshtchevsky U, Machado BE, Brunet A, Jarosz DF | Developmental cell | 38810654 | Dev Cell | 2024 Jul 22 | https://www.ncbi.nlm.nih.gov/pubmed/38810654 |
The Hsp90 Molecular Chaperone as a Global Modifier of the Genotype-Phenotype-Fitness Map: An Evolutionary Perspective. | Aguilar-Rodríguez J, Jakobson CM, Jarosz DF | Journal of molecular biology | 39481633 | J Mol Biol | 2024 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/39481633 |
A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects. | Jakobson CM, Hartl J, Trébulle P, Mülleder M, Jarosz DF, Ralser M | bioRxiv : the preprint server for biology | 39484408 | bioRxiv | 2024 Oct 22 | https://www.ncbi.nlm.nih.gov/pubmed/39484408 |
Protein self-assembly: A new frontier in cell signaling. | Saad S, Jarosz DF | Current opinion in cell biology | 33493989 | Curr Opin Cell Biol | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33493989 |
The Hunt for Ancient Prions: Archaeal Prion-Like Domains Form Amyloid-Based Epigenetic Elements. | Zajkowski T, Lee MD, Mondal SS, Carbajal A, Dec R, Brennock PD, Piast RW, Snyder JE, Bense NB, Dzwolak W, Jarosz DF, Rothschild LJ | Molecular biology and evolution | 33480998 | Mol Biol Evol | 2021 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/33480998 |
Molecular Origins of Complex Heritability in Natural Genotype-to-Phenotype Relationships. | Jakobson CM, Jarosz DF | Cell systems | 31054809 | Cell Syst | 2019 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/31054809 |
Pervasive function and evidence for selection across standing genetic variation in S. cerevisiae. | Jakobson CM, She R, Jarosz DF | Nature communications | 30874558 | Nat Commun | 2019 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/30874558 |
It Pays To Be in Phase. | Itakura AK, Futia RA, Jarosz DF | Biochemistry | 29509425 | Biochemistry | 2018 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/29509425 |
Mapping Causal Variants with Single-Nucleotide Resolution Reveals Biochemical Drivers of Phenotypic Change. | She R, Jarosz DF | Cell | 29373829 | Cell | 2018 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/29373829 |
Protein-Based Inheritance: Epigenetics beyond the Chromosome. | Harvey ZH, Chen Y, Jarosz DF | Molecular cell | 29153393 | Mol Cell | 2018 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/29153393 |
Widespread Prion-Based Control of Growth and Differentiation Strategies in Saccharomyces cerevisiae. | Itakura AK, Chakravarty AK, Jakobson CM, Jarosz DF | Molecular cell | 31757756 | Mol Cell | 2020 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/31757756 |
Hsp90 shapes adaptation by controlling the fitness consequences of regulatory variation. | Jakobson CM, Aguilar-Rodríguez J, Jarosz DF | bioRxiv : the preprint server for biology | 37961536 | bioRxiv | 2023 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/37961536 |
Mutations, protein homeostasis, and epigenetic control of genome integrity. | Xie JL, Jarosz DF | DNA repair | 30181040 | DNA Repair (Amst) | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30181040 |
High-throughput Screening for Protein-based Inheritance in S. cerevisiae. | Byers JS, Jarosz DF | Journal of visualized experiments : JoVE | 28809826 | J Vis Exp | 2017 Aug 8 | https://www.ncbi.nlm.nih.gov/pubmed/28809826 |
Protein aggregation and the evolution of stress resistance in clinical yeast. | Chen YR, Ziv I, Swaminathan K, Elias JE, Jarosz DF | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 33866806 | Philos Trans R Soc Lond B Biol Sci | 2021 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/33866806 |
More than Just a Phase: Prions at the Crossroads of Epigenetic Inheritance and Evolutionary Change. | Chakravarty AK, Jarosz DF | Journal of molecular biology | 30031007 | J Mol Biol | 2018 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/30031007 |
A CRISPR Approach to Neurodegenerative Diseases. | Kampmann M | Trends in molecular medicine | 28478951 | Trends Mol Med | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28478951 |
LRP1 is a master regulator of tau uptake and spread. | Rauch JN, Luna G, Guzman E, Audouard M, Challis C, Sibih YE, Leshuk C, Hernandez I, Wegmann S, Hyman BT, Gradinaru V, Kampmann M, Kosik KS | Nature | 32296178 | Nature | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32296178 |
Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation. | Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M | The Journal of biological chemistry | 31578281 | J Biol Chem | 2019 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/31578281 |
Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance. | Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, Ary BE, Bauer DP, Bergman ID, Brunetti RM, Chio CM, Dai SA, Dickinson MS, Elledge SK, Helsell CVM, Hendel NL, Kang E, Kern N, Khoroshkin MS, Kirkemo LL, Lewis GR, Lou K, Marin WM, Maxwell AM, McTigue PF, Myers-Turnbull D, Nagy TL, Natale AM, Oltion K, Pourmal S, Reder GK, Rettko NJ, Rohweder PJ, Schwarz DMC, Tan SK, Thomas PV, Tibble RW, Town JP, Tsai MK, Ugur FS, Wassarman DR, Wolff AM, Wu TS, Bogdanoff D, Li J, Thorn KS, O'Conchúir S, Swaney DL, Chow ED, Madhani HD, Redding S, Bolon DN, Kortemme T, DeRisi JL, Kampmann M, Fraser JS | Biology open | 30037883 | Biol Open | 2018 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/30037883 |
An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes. | Oltion K, Carelli JD, Yang T, See SK, Wang HY, Kampmann M, Taunton J | Cell | 36638793 | Cell | 2023 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/36638793 |
Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability. | Abrams J, Arhar T, Mok SA, Taylor IR, Kampmann M, Gestwicki JE | Cell stress & chaperones | 33547632 | Cell Stress Chaperones | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33547632 |
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states. | Dräger NM, Sattler SM, Huang CT, Teter OM, Leng K, Hashemi SH, Hong J, Aviles G, Clelland CD, Zhan L, Udeochu JC, Kodama L, Singleton AB, Nalls MA, Ichida J, Ward ME, Faghri F, Gan L, Kampmann M | Nature neuroscience | 35953545 | Nat Neurosci | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/35953545 |
Dual gene activation and knockout screen reveals directional dependencies in genetic networks. | Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT | Nature biotechnology | 29334369 | Nat Biotechnol | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29334369 |
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity. | Zhang YJ, Guo L, Gonzales PK, Gendron TF, Wu Y, Jansen-West K, O'Raw AD, Pickles SR, Prudencio M, Carlomagno Y, Gachechiladze MA, Ludwig C, Tian R, Chew J, DeTure M, Lin WL, Tong J, Daughrity LM, Yue M, Song Y, Andersen JW, Castanedes-Casey M, Kurti A, Datta A, Antognetti G, McCampbell A, Rademakers R, Oskarsson B, Dickson DW, Kampmann M, Ward ME, Fryer JD, Link CD, Shorter J, Petrucelli L | Science (New York, N.Y.) | 30765536 | Science | 2019 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/30765536 |
A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure. | Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K | PLoS biology | 30148842 | PLoS Biol | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30148842 |
NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems. | Biebl MM, Delhommel F, Faust O, Zak KM, Agam G, Guo X, Mühlhofer M, Dahiya V, Hillebrand D, Popowicz GM, Kampmann M, Lamb DC, Rosenzweig R, Sattler M, Buchner J | Molecular cell | 35063133 | Mol Cell | 2022 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/35063133 |
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. | Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS | Cell | 33838111 | Cell | 2021 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/33838111 |
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine. | Kampmann M | ACS chemical biology | 29035510 | ACS Chem Biol | 2018 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/29035510 |
Mapping the Genetic Landscape of Human Cells. | Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA | Cell | 30033366 | Cell | 2018 Aug 9 | https://www.ncbi.nlm.nih.gov/pubmed/30033366 |
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. | Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ | Cell | 30053424 | Cell | 2018 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/30053424 |
Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs). | Rauch JN, Chen JJ, Sorum AW, Miller GM, Sharf T, See SK, Hsieh-Wilson LC, Kampmann M, Kosik KS | Scientific reports | 29686391 | Sci Rep | 2018 Apr 23 | https://www.ncbi.nlm.nih.gov/pubmed/29686391 |
Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells. | Kampmann M | Chemical communications (Cambridge, England) | 28487920 | Chem Commun (Camb) | 2017 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/28487920 |
A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling. | Semesta KM, Tian R, Kampmann M, von Zastrow M, Tsvetanova NG | PLoS genetics | 33052901 | PLoS Genet | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33052901 |
Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes. | Kanfer G, Sarraf SA, Maman Y, Baldwin H, Dominguez-Martin E, Johnson KR, Ward ME, Kampmann M, Lippincott-Schwartz J, Youle RJ | The Journal of cell biology | 33464298 | J Cell Biol | 2021 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/33464298 |
CRISPulator: a discrete simulation tool for pooled genetic screens. | Nagy T, Kampmann M | BMC bioinformatics | 28732459 | BMC Bioinformatics | 2017 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/28732459 |
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. | Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS | eLife | 27661255 | Elife | 2016 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/27661255 |
The mTOR Complex Controls HIV Latency. | Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E | Cell host & microbe | 27978436 | Cell Host Microbe | 2016 Dec 14 | https://www.ncbi.nlm.nih.gov/pubmed/27978436 |
CRISPR-based functional genomics for neurological disease. | Kampmann M | Nature reviews. Neurology | 32641861 | Nat Rev Neurol | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32641861 |
Defining the ATPome reveals cross-optimization of metabolic pathways. | Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K | Nature communications | 32859923 | Nat Commun | 2020 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/32859923 |
Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding. | Newberry RW, Arhar T, Costello J, Hartoularos GC, Maxwell AM, Naing ZZC, Pittman M, Reddy NR, Schwarz DMC, Wassarman DR, Wu TS, Barrero D, Caggiano C, Catching A, Cavazos TB, Estes LS, Faust B, Fink EA, Goldman MA, Gomez YK, Gordon MG, Gunsalus LM, Hoppe N, Jaime-Garza M, Johnson MC, Jones MG, Kung AF, Lopez KE, Lumpe J, Martyn C, McCarthy EE, Miller-Vedam LE, Navarro EJ, Palar A, Pellegrino J, Saylor W, Stephens CA, Strickland J, Torosyan H, Wankowicz SA, Wong DR, Wong G, Redding S, Chow ED, DeGrado WF, Kampmann M | ACS chemical biology | 32786289 | ACS Chem Biol | 2020 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/32786289 |
CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons. | Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M | Neuron | 31422865 | Neuron | 2019 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/31422865 |
Global Proteome Remodeling during ER Stress Involves Hac1-Driven Expression of Long Undecoded Transcript Isoforms. | Van Dalfsen KM, Hodapp S, Keskin A, Otto GM, Berdan CA, Higdon A, Cheunkarndee T, Nomura DK, Jovanovic M, Brar GA | Developmental cell | 30016623 | Dev Cell | 2018 Jul 16 | https://www.ncbi.nlm.nih.gov/pubmed/30016623 |
Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast. | Eisenberg AR, Higdon AL, Hollerer I, Fields AP, Jungreis I, Diamond PD, Kellis M, Jovanovic M, Brar GA | Cell systems | 32710835 | Cell Syst | 2020 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/32710835 |
Global mapping of translation initiation sites by TIS profiling in budding yeast. | Hollerer I, Powers EN, Brar GA | STAR protocols | 33458709 | STAR Protoc | 2021 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/33458709 |
Pervasive, Coordinated Protein-Level Changes Driven by Transcript Isoform Switching during Meiosis. | Cheng Z, Otto GM, Powers EN, Keskin A, Mertins P, Carr SA, Jovanovic M, Brar GA | Cell | 29474919 | Cell | 2018 Feb 22 | https://www.ncbi.nlm.nih.gov/pubmed/29474919 |
Precise Post-translational Tuning Occurs for Most Protein Complex Components during Meiosis. | Eisenberg AR, Higdon A, Keskin A, Hodapp S, Jovanovic M, Brar GA | Cell reports | 30590036 | Cell Rep | 2018 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/30590036 |
Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate. | Cheng Z, Mugler CF, Keskin A, Hodapp S, Chan LY, Weis K, Mertins P, Regev A, Jovanovic M, Brar GA | Molecular cell | 30503772 | Mol Cell | 2019 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/30503772 |
Tunable Transcriptional Interference at the Endogenous Alcohol Dehydrogenase Gene Locus in Drosophila melanogaster. | Jorgensen V, Chen J, Vander Wende H, Harris DE, McCarthy A, Breznak S, Wong-Deyrup SW, Chen Y, Rangan P, Brar GA, Sawyer EM, Chan LY, Ünal E | G3 (Bethesda, Md.) | 32213532 | G3 (Bethesda) | 2020 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/32213532 |
Strategies and Challenges in Identifying Function for Thousands of sORF-Encoded Peptides in Meiosis. | Hollerer I, Higdon A, Brar GA | Proteomics | 28929627 | Proteomics | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/28929627 |
Beyond the Triplet Code: Context Cues Transform Translation. | Brar GA | Cell | 27984720 | Cell | 2016 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/27984720 |
Global translation inhibition yields condition-dependent de-repression of ribosome biogenesis mRNAs. | Cheng Z, Brar GA | Nucleic acids research | 30937450 | Nucleic Acids Res | 2019 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/30937450 |
Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells. | Hollerer I, Barker JC, Jorgensen V, Tresenrider A, Dugast-Darzacq C, Chan LY, Darzacq X, Tjian R, Ünal E, Brar GA | G3 (Bethesda, Md.) | 30723103 | G3 (Bethesda) | 2019 Apr 9 | https://www.ncbi.nlm.nih.gov/pubmed/30723103 |
The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. | Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S | eLife | 31612858 | Elife | 2019 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/31612858 |
A Spatial Interactome Reveals the Protein Organization of the Algal CO(2)-Concentrating Mechanism. | Mackinder LCM, Chen C, Leib RD, Patena W, Blum SR, Rodman M, Ramundo S, Adams CM, Jonikas MC | Cell | 28938113 | Cell | 2017 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/28938113 |
Increasing the uptake of carbon dioxide. | Franklin E, Jonikas M | eLife | 33270556 | Elife | 2020 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/33270556 |
Effects of microcompartmentation on flux distribution and metabolic pools in Chlamydomonas reinhardtii chloroplasts. | Küken A, Sommer F, Yaneva-Roder L, Mackinder LC, Höhne M, Geimer S, Jonikas MC, Schroda M, Stitt M, Nikoloski Z, Mettler-Altmann T | eLife | 30306890 | Elife | 2018 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/30306890 |
A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis. | Li X, Patena W, Fauser F, Jinkerson RE, Saroussi S, Meyer MT, Ivanova N, Robertson JM, Yue R, Zhang R, Vilarrasa-Blasi J, Wittkopp TM, Ramundo S, Blum SR, Goh A, Laudon M, Srikumar T, Lefebvre PA, Grossman AR, Jonikas MC | Nature genetics | 30886426 | Nat Genet | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30886426 |
The structural basis of Rubisco phase separation in the pyrenoid. | He S, Chou HT, Matthies D, Wunder T, Meyer MT, Atkinson N, Martinez-Sanchez A, Jeffrey PD, Port SA, Patena W, He G, Chen VK, Hughson FM, McCormick AJ, Mueller-Cajar O, Engel BD, Yu Z, Jonikas MC | Nature plants | 33230314 | Nat Plants | 2020 Dec | https://www.ncbi.nlm.nih.gov/pubmed/33230314 |
Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii. | Fauser F, Vilarrasa-Blasi J, Onishi M, Ramundo S, Patena W, Millican M, Osaki J, Philp C, Nemeth M, Salomé PA, Li X, Wakao S, Kim RG, Kaye Y, Grossman AR, Niyogi KK, Merchant SS, Cutler SR, Walter P, Dinneny JR, Jonikas MC, Jinkerson RE | Nature genetics | 35513725 | Nat Genet | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35513725 |
Multi-omics analysis of green lineage osmotic stress pathways unveils crucial roles of different cellular compartments. | Vilarrasa-Blasi J, Vellosillo T, Jinkerson RE, Fauser F, Xiang T, Minkoff BB, Wang L, Kniazev K, Guzman M, Osaki J, Barrett-Wilt GA, Sussman MR, Jonikas MC, Dinneny JR | Nature communications | 39013881 | Nat Commun | 2024 Jul 16 | https://www.ncbi.nlm.nih.gov/pubmed/39013881 |
Prospects for Engineering Biophysical CO(2) Concentrating Mechanisms into Land Plants to Enhance Yields. | Hennacy JH, Jonikas MC | Annual review of plant biology | 32151155 | Annu Rev Plant Biol | 2020 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/32151155 |
Assembly of the algal CO(2)-fixing organelle, the pyrenoid, is guided by a Rubisco-binding motif. | Meyer MT, Itakura AK, Patena W, Wang L, He S, Emrich-Mills T, Lau CS, Yates G, Mackinder LCM, Jonikas MC | Science advances | 33177094 | Sci Adv | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33177094 |
Phase separation in biology and disease-a symposium report. | Cable J, Brangwynne C, Seydoux G, Cowburn D, Pappu RV, Castañeda CA, Berchowitz LE, Chen Z, Jonikas M, Dernburg A, Mittag T, Fawzi NL | Annals of the New York Academy of Sciences | 31199001 | Ann N Y Acad Sci | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31199001 |
A Rubisco-binding protein is required for normal pyrenoid number and starch sheath morphology in Chlamydomonas reinhardtii. | Itakura AK, Chan KX, Atkinson N, Pallesen L, Wang L, Reeves G, Patena W, Caspari O, Roth R, Goodenough U, McCormick AJ, Griffiths H, Jonikas MC | Proceedings of the National Academy of Sciences of the United States of America | 31455733 | Proc Natl Acad Sci U S A | 2019 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/31455733 |
Rigidity enhances a magic-number effect in polymer phase separation. | Xu B, He G, Weiner BG, Ronceray P, Meir Y, Jonikas MC, Wingreen NS | Nature communications | 32214099 | Nat Commun | 2020 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/32214099 |
A two-step mechanism for the inactivation of microtubule organizing center function at the centrosome. | Magescas J, Zonka JC, Feldman JL | eLife | 31246171 | Elife | 2019 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/31246171 |
Cytoskeletal variations in an asymmetric cell division support diversity in nematode sperm size and sex ratios. | Winter ES, Schwarz A, Fabig G, Feldman JL, Pires-daSilva A, Müller-Reichert T, Sadler PL, Shakes DC | Development (Cambridge, England) | 28827395 | Development | 2017 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/28827395 |
Inherited apicobasal polarity defines the key features of axon-dendrite polarity in a sensory neuron. | Lee J, Magescas J, Fetter RD, Feldman JL, Shen K | Current biology : CB | 34270949 | Curr Biol | 2021 Sep 13 | https://www.ncbi.nlm.nih.gov/pubmed/34270949 |
Apical PAR complex proteins protect against programmed epithelial assaults to create a continuous and functional intestinal lumen. | Sallee MD, Pickett MA, Feldman JL | eLife | 34137371 | Elife | 2021 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/34137371 |
Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output. | Lessenger AT, Skotheim JM, Swaffer MP, Feldman JL | The Journal of cell biology | 39652010 | J Cell Biol | 2025 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/39652010 |
Tissue-specific degradation of essential centrosome components reveals distinct microtubule populations at microtubule organizing centers. | Sallee MD, Zonka JC, Skokan TD, Raftrey BC, Feldman JL | PLoS biology | 30080857 | PLoS Biol | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30080857 |
A proximity labeling protocol to probe proximity interactions in C. elegans. | Sanchez AD, Feldman JL | STAR protocols | 34927095 | STAR Protoc | 2021 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/34927095 |
Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites. | Liang X, Kokes M, Fetter RD, Sallee MD, Moore AW, Feldman JL, Shen K | eLife | 32657271 | Elife | 2020 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/32657271 |
Context matters: Lessons in epithelial polarity from the Caenorhabditis elegans intestine and other tissues. | Naturale VF, Pickett MA, Feldman JL | Current topics in developmental biology | 37100523 | Curr Top Dev Biol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37100523 |
Proximity labeling reveals non-centrosomal microtubule-organizing center components required for microtubule growth and localization. | Sanchez AD, Branon TC, Cote LE, Papagiannakis A, Liang X, Pickett MA, Shen K, Jacobs-Wagner C, Ting AY, Feldman JL | Current biology : CB | 34242576 | Curr Biol | 2021 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/34242576 |
Microtubule-organizing centers: from the centrosome to non-centrosomal sites. | Sanchez AD, Feldman JL | Current opinion in cell biology | 27666167 | Curr Opin Cell Biol | 2017 Feb | https://www.ncbi.nlm.nih.gov/pubmed/27666167 |
Visualizing the metazoan proliferation-quiescence decision in vivo. | Adikes RC, Kohrman AQ, Martinez MAQ, Palmisano NJ, Smith JJ, Medwig-Kinney TN, Min M, Sallee MD, Ahmed OB, Kim N, Liu S, Morabito RD, Weeks N, Zhao Q, Zhang W, Feldman JL, Barkoulas M, Pani AM, Spencer SL, Martin BL, Matus DQ | eLife | 33350383 | Elife | 2020 Dec 22 | https://www.ncbi.nlm.nih.gov/pubmed/33350383 |
Persistent cell contacts enable E-cadherin/HMR-1- and PAR-3-based symmetry breaking within a developing C. elegans epithelium. | Naturale VF, Pickett MA, Feldman JL | Developmental cell | 37552986 | Dev Cell | 2023 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/37552986 |
Centriole-less pericentriolar material serves as a microtubule organizing center at the base of C. elegans sensory cilia. | Magescas J, Eskinazi S, Tran MV, Feldman JL | Current biology : CB | 33798428 | Curr Biol | 2021 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/33798428 |
Efficient proximity labeling in living cells and organisms with TurboID. | Branon TC, Bosch JA, Sanchez AD, Udeshi ND, Svinkina T, Carr SA, Feldman JL, Perrimon N, Ting AY | Nature biotechnology | 30125270 | Nat Biotechnol | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30125270 |
A Polarizing Issue: Diversity in the Mechanisms Underlying Apico-Basolateral Polarization In Vivo. | Pickett MA, Naturale VF, Feldman JL | Annual review of cell and developmental biology | 31461314 | Annu Rev Cell Dev Biol | 2019 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/31461314 |
Separable mechanisms drive local and global polarity establishment in the Caenorhabditiselegans intestinal epithelium. | Pickett MA, Sallee MD, Cote L, Naturale VF, Akpinaroglu D, Lee J, Shen K, Feldman JL | Development (Cambridge, England) | 36264257 | Development | 2022 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/36264257 |
Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development. | Alavattam KG, Maezawa S, Sakashita A, Khoury H, Barski A, Kaplan N, Namekawa SH | Nature structural & molecular biology | 30778237 | Nat Struct Mol Biol | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30778237 |
Analysis of ChIP-Seq and RNA-Seq Data with BioWardrobe. | Vallabh S, Kartashov AV, Barski A | Methods in molecular biology (Clifton, N.J.) | 29767371 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29767371 |
Reuse of public, genome-wide, murine eosinophil expression data for hypotheses development. | Grace JO, Malik A, Reichman H, Munitz A, Barski A, Fulkerson PC | Journal of leukocyte biology | 29758095 | J Leukoc Biol | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29758095 |
Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline. | Maezawa S, Hasegawa K, Yukawa M, Kubo N, Sakashita A, Alavattam KG, Sin HS, Kartashov AV, Sasaki H, Barski A, Namekawa SH | Proceedings of the National Academy of Sciences of the United States of America | 29686098 | Proc Natl Acad Sci U S A | 2018 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/29686098 |
PRC1 suppresses a female gene regulatory network to ensure testicular differentiation. | Maezawa S, Yukawa M, Hasegawa K, Sugiyama R, Iizuka M, Hu M, Sakashita A, Vidal M, Koseki H, Barski A, DeFalco T, Namekawa SH | Cell death & disease | 37542070 | Cell Death Dis | 2023 Aug 4 | https://www.ncbi.nlm.nih.gov/pubmed/37542070 |
Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity. | Harley JB, Chen X, Pujato M, Miller D, Maddox A, Forney C, Magnusen AF, Lynch A, Chetal K, Yukawa M, Barski A, Salomonis N, Kaufman KM, Kottyan LC, Weirauch MT | Nature genetics | 29662164 | Nat Genet | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29662164 |
FOXF1 transcription factor promotes lung regeneration after partial pneumonectomy. | Bolte C, Flood HM, Ren X, Jagannathan S, Barski A, Kalin TV, Kalinichenko VV | Scientific reports | 28878348 | Sci Rep | 2017 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/28878348 |
Polycomb directs timely activation of germline genes in spermatogenesis. | Maezawa S, Hasegawa K, Yukawa M, Sakashita A, Alavattam KG, Andreassen PR, Vidal M, Koseki H, Barski A, Namekawa SH | Genes & development | 28924034 | Genes Dev | 2017 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/28924034 |
Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. | Kelly D, Kotliar M, Woo V, Jagannathan S, Whitt J, Moncivaiz J, Aronow BJ, Dubinsky MC, Hyams JS, Markowitz JF, Baldassano RN, Stephens MC, Walters TD, Kugathasan S, Haberman Y, Sundaram N, Rosen MJ, Helmrath M, Karns R, Barski A, Denson LA, Alenghat T | JCI insight | 30232290 | JCI Insight | 2018 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/30232290 |
SCML2 promotes heterochromatin organization in late spermatogenesis. | Maezawa S, Hasegawa K, Alavattam KG, Funakoshi M, Sato T, Barski A, Namekawa SH | Journal of cell science | 30097555 | J Cell Sci | 2018 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/30097555 |
Chromatin Preparation from Murine Eosinophils for Genome-Wide Analyses. | Bouffi C, Barski A, Fulkerson PC | Methods in molecular biology (Clifton, N.J.) | 29956158 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/29956158 |
Endogenous retroviruses drive species-specific germline transcriptomes in mammals. | Sakashita A, Maezawa S, Takahashi K, Alavattam KG, Yukawa M, Hu YC, Kojima S, Parrish NF, Barski A, Pavlicev M, Namekawa SH | Nature structural & molecular biology | 32895553 | Nat Struct Mol Biol | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32895553 |
Nuclear Factor κB1/RelA Mediates Inflammation in Human Lung Epithelial Cells at Atmospheric Oxygen Levels. | Jagannathan L, Jose CC, Arita A, Kluz T, Sun H, Zhang X, Yao Y, Kartashov AV, Barski A, Costa M, Cuddapah S | Journal of cellular physiology | 26588041 | J Cell Physiol | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/26588041 |
AP-1 activity induced by co-stimulation is required for chromatin opening during T cell activation. | Yukawa M, Jagannathan S, Vallabh S, Kartashov AV, Chen X, Weirauch MT, Barski A | The Journal of experimental medicine | 31653690 | J Exp Med | 2020 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/31653690 |
RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes. | Adams SR, Maezawa S, Alavattam KG, Abe H, Sakashita A, Shroder M, Broering TJ, Sroga Rios J, Thomas MA, Lin X, Price CM, Barski A, Andreassen PR, Namekawa SH | PLoS genetics | 29462142 | PLoS Genet | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29462142 |
Polycomb repressive complex 1 controls uterine decidualization. | Bian F, Gao F, Kartashov AV, Jegga AG, Barski A, Das SK | Scientific reports | 27181215 | Sci Rep | 2016 May 16 | https://www.ncbi.nlm.nih.gov/pubmed/27181215 |
Rapid Recall Ability of Memory T cells is Encoded in their Epigenome. | Barski A, Cuddapah S, Kartashov AV, Liu C, Imamichi H, Yang W, Peng W, Lane HC, Zhao K | Scientific reports | 28054639 | Sci Rep | 2017 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/28054639 |
Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs. | Stevens ML, Chaturvedi P, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM | Development (Cambridge, England) | 28219948 | Development | 2017 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/28219948 |
Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition. | Maezawa S, Sakashita A, Yukawa M, Chen X, Takahashi K, Alavattam KG, Nakata I, Weirauch MT, Barski A, Namekawa SH | Nature structural & molecular biology | 32895557 | Nat Struct Mol Biol | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32895557 |
Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression. | Yue M, Ogawa A, Yamada N, Charles Richard JL, Barski A, Ogawa Y | PLoS genetics | 28686623 | PLoS Genet | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28686623 |
Site-specific DNA demethylation during spermatogenesis presets the sites of nucleosome retention in mouse sperm. | Maezawa S, Yukawa M, Sakashita A, Barski A, Namekawa SH | bioRxiv : the preprint server for biology | 39829778 | bioRxiv | 2025 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/39829778 |
Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14. | Miller DE, Forney C, Rochman M, Cranert S, Habel J, Rymer J, Lynch A, Schroeder C, Lee J, Sauder A, Smith Q, Chawla M, Trimarchi MP, Lu X, Fjellman E, Brusilovsky M, Barski A, Waggoner S, Weirauch MT, Rothenberg ME, Kottyan LC | G3 (Bethesda, Md.) | 30626591 | G3 (Bethesda) | 2019 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/30626591 |
A rapidly evolved domain, the SCML2 DNA-binding repeats, contributes to chromatin binding of mouse SCML2†. | Maezawa S, Alavattam KG, Tatara M, Nagai R, Barski A, Namekawa SH | Biology of reproduction | 30137219 | Biol Reprod | 2019 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/30137219 |
TSLP signaling in CD4(+) T cells programs a pathogenic T helper 2 cell state. | Rochman Y, Dienger-Stambaugh K, Richgels PK, Lewkowich IP, Kartashov AV, Barski A, Khurana Hershey GK, Leonard WJ, Singh H | Science signaling | 29535264 | Sci Signal | 2018 Mar 13 | https://www.ncbi.nlm.nih.gov/pubmed/29535264 |
CWL-Airflow: a lightweight pipeline manager supporting Common Workflow Language. | Kotliar M, Kartashov AV, Barski A | GigaScience | 31321430 | Gigascience | 2019 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/31321430 |
Nuclear Deformation Causes DNA Damage by Increasing Replication Stress. | Shah P, Hobson CM, Cheng S, Colville MJ, Paszek MJ, Superfine R, Lammerding J | Current biology : CB | 33326770 | Curr Biol | 2021 Feb 22 | https://www.ncbi.nlm.nih.gov/pubmed/33326770 |
Tissue mechanics, an important regulator of development and disease. | Ayad NME, Kaushik S, Weaver VM | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 31431174 | Philos Trans R Soc Lond B Biol Sci | 2019 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/31431174 |
Physical biology of the cancer cell glycocalyx. | Chin-Hun Kuo J, Gandhi JG, Zia RN, Paszek MJ | Nature physics | 33859716 | Nat Phys | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/33859716 |
Immunoengineering can overcome the glycocalyx armour of cancer cells. | Park S, Colville MJ, Paek JH, Shurer CR, Singh A, Secor EJ, Sailer CJ, Huang LT, Kuo JC, Goudge MC, Su J, Kim M, DeLisa MP, Neelamegham S, Lammerding J, Zipfel WR, Fischbach C, Reesink HL, Paszek MJ | Nature materials | 38361041 | Nat Mater | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38361041 |
Mucin-coating technologies for protection and reduced aggregation of cellular production systems. | Shurer CR, Head SE, Goudge MC, Paszek MJ | Biotechnology and bioengineering | 30636317 | Biotechnol Bioeng | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/30636317 |
Genetically Encoded Toolbox for Glycocalyx Engineering: Tunable Control of Cell Adhesion, Survival, and Cancer Cell Behaviors. | Shurer CR, Colville MJ, Gupta VK, Head SE, Kai F, Lakins JN, Paszek MJ | ACS biomaterials science & engineering | 29805991 | ACS Biomater Sci Eng | 2018 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/29805991 |
Stable recombinant production of codon-scrambled lubricin and mucin in human cells. | Shurer CR, Wang Y, Feeney E, Head SE, Zhang VX, Su J, Cheng Z, Stark MA, Bonassar LJ, Reesink HL, Paszek MJ | Biotechnology and bioengineering | 30684357 | Biotechnol Bioeng | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30684357 |
Recombinant manufacturing of multispecies biolubricants. | Colville MJ, Huang LT, Schmidt S, Chen K, Vishwanath K, Su J, Williams RM, Bonassar LJ, Reesink HL, Paszek MJ | bioRxiv : the preprint server for biology | 38746339 | bioRxiv | 2024 May 5 | https://www.ncbi.nlm.nih.gov/pubmed/38746339 |
Equilibrium Modeling of the Mechanics and Structure of the Cancer Glycocalyx. | Gandhi JG, Koch DL, Paszek MJ | Biophysical journal | 30736980 | Biophys J | 2019 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/30736980 |
Sequence-Specific Mucins for Glycocalyx Engineering. | Pan H, Colville MJ, Supekar NT, Azadi P, Paszek MJ | ACS synthetic biology | 31500407 | ACS Synth Biol | 2019 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/31500407 |
Physical Principles of Membrane Shape Regulation by the Glycocalyx. | Shurer CR, Kuo JC, Roberts LM, Gandhi JG, Colville MJ, Enoki TA, Pan H, Su J, Noble JM, Hollander MJ, O'Donnell JP, Yin R, Pedram K, Möckl L, Kourkoutis LF, Moerner WE, Bertozzi CR, Feigenson GW, Reesink HL, Paszek MJ | Cell | 31056282 | Cell | 2019 Jun 13 | https://www.ncbi.nlm.nih.gov/pubmed/31056282 |
Litmus-Body: A Molecularly Targeted Sensor for Cell-Surface pH Measurements. | Kuo JC, Goudge MC, Metzloff AE, Huang LT, Colville MJ, Park S, Zipfel WR, Paszek MJ | ACS sensors | 32337979 | ACS Sens | 2020 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/32337979 |
Glycocalyx Curving the Membrane: Forces Emerging from the Cell Exterior. | Kuo JC, Paszek MJ | Annual review of cell and developmental biology | 34613816 | Annu Rev Cell Dev Biol | 2021 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/34613816 |
An ERAD-independent role for rhomboid pseudoprotease Dfm1 in mediating sphingolipid homeostasis. | Bhaduri S, Aguayo A, Ohno Y, Proietto M, Jung J, Wang I, Kandel R, Singh N, Ibrahim I, Fulzele A, Bennett EJ, Kihara A, Neal SE | The EMBO journal | 36350249 | EMBO J | 2023 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/36350249 |
The C-Terminal RGG Domain of Human Lsm4 Promotes Processing Body Formation Stimulated by Arginine Dimethylation. | Arribas-Layton M, Dennis J, Bennett EJ, Damgaard CK, Lykke-Andersen J | Molecular and cellular biology | 27247266 | Mol Cell Biol | 2016 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/27247266 |
Active Protein Neddylation or Ubiquitylation Is Dispensable for Stress Granule Dynamics. | Markmiller S, Fulzele A, Higgins R, Leonard M, Yeo GW, Bennett EJ | Cell reports | 31042464 | Cell Rep | 2019 Apr 30 | https://www.ncbi.nlm.nih.gov/pubmed/31042464 |
Using the Ubiquitin-modified Proteome to Monitor Distinct and Spatially Restricted Protein Homeostasis Dysfunction. | Gendron JM, Webb K, Yang B, Rising L, Zuzow N, Bennett EJ | Molecular & cellular proteomics : MCP | 27185884 | Mol Cell Proteomics | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27185884 |
Ribosome quality control activity potentiates vaccinia virus protein synthesis during infection. | Sundaramoorthy E, Ryan AP, Fulzele A, Leonard M, Daugherty MD, Bennett EJ | Journal of cell science | 33912921 | J Cell Sci | 2021 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/33912921 |
Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized. | Garshott DM, Sundaramoorthy E, Leonard M, Bennett EJ | eLife | 32011234 | Elife | 2020 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/32011234 |
In vivo mapping of tissue- and subcellular-specific proteomes in Caenorhabditis elegans. | Reinke AW, Mak R, Troemel ER, Bennett EJ | Science advances | 28508060 | Sci Adv | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28508060 |
Ubiquitin diGLY Proteomics as an Approach to Identify and Quantify the Ubiquitin-Modified Proteome. | Fulzele A, Bennett EJ | Methods in molecular biology (Clifton, N.J.) | 30242721 | Methods Mol Biol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30242721 |
Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. | Lumpkin RJ, Gu H, Zhu Y, Leonard M, Ahmad AS, Clauser KR, Meyer JG, Bennett EJ, Komives EA | Nature communications | 29079793 | Nat Commun | 2017 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/29079793 |
Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches. | Zuzow N, Ghosh A, Leonard M, Liao J, Yang B, Bennett EJ | Molecular biology of the cell | 29540532 | Mol Biol Cell | 2018 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/29540532 |
Proteome complexity and the forces that drive proteome imbalance. | Harper JW, Bennett EJ | Nature | 27629639 | Nature | 2016 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/27629639 |
A Cdc48 "Retrochaperone" Function Is Required for the Solubility of Retrotranslocated, Integral Membrane Endoplasmic Reticulum-associated Degradation (ERAD-M) Substrates. | Neal S, Mak R, Bennett EJ, Hampton R | The Journal of biological chemistry | 28077573 | J Biol Chem | 2017 Feb 24 | https://www.ncbi.nlm.nih.gov/pubmed/28077573 |
ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation. | Sundaramoorthy E, Leonard M, Mak R, Liao J, Fulzele A, Bennett EJ | Molecular cell | 28132843 | Mol Cell | 2017 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/28132843 |
Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. | Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW | Cell | 29373831 | Cell | 2018 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/29373831 |
Bombardier Enables Delivery of Short-Form Bomanins in the Drosophila Toll Response. | Lin SJH, Fulzele A, Cohen LB, Bennett EJ, Wasserman SA | Frontiers in immunology | 31998316 | Front Immunol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31998316 |
EDF1 coordinates cellular responses to ribosome collisions. | Sinha NK, Ordureau A, Best K, Saba JA, Zinshteyn B, Sundaramoorthy E, Fulzele A, Garshott DM, Denk T, Thoms M, Paulo JA, Harper JW, Bennett EJ, Beckmann R, Green R | eLife | 32744497 | Elife | 2020 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/32744497 |
iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation. | Garshott DM, An H, Sundaramoorthy E, Leonard M, Vicary A, Harper JW, Bennett EJ | Cell reports | 34469731 | Cell Rep | 2021 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/34469731 |
Electron Decoupling with Dynamic Nuclear Polarization in Rotating Solids. | Saliba EP, Sesti EL, Scott FJ, Albert BJ, Choi EJ, Alaniva N, Gao C, Barnes AB | Journal of the American Chemical Society | 28429936 | J Am Chem Soc | 2017 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/28429936 |
Dynamic Nuclear Polarization with Electron Decoupling in Intact Human Cells and Cell Lysates. | Judge PT, Sesti EL, Price LE, Albert BJ, Alaniva N, Saliba EP, Halbritter T, Sigurdsson ST, Kyei GB, Barnes AB | The journal of physical chemistry. B | 32083876 | J Phys Chem B | 2020 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/32083876 |
Sensitivity analysis of magic angle spinning dynamic nuclear polarization below 6 K. | Judge PT, Sesti EL, Saliba EP, Alaniva N, Halbritter T, Sigurdsson ST, Barnes AB | Journal of magnetic resonance (San Diego, Calif. : 1997) | 31212198 | J Magn Reson | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31212198 |
Magic angle spinning spheres. | Chen P, Albert BJ, Gao C, Alaniva N, Price LE, Scott FJ, Saliba EP, Sesti EL, Judge PT, Fisher EW, Barnes AB | Science advances | 30255153 | Sci Adv | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30255153 |
Electron decoupling with cross polarization and dynamic nuclear polarization below 6 K. | Sesti EL, Saliba EP, Alaniva N, Barnes AB | Journal of magnetic resonance (San Diego, Calif. : 1997) | 30077145 | J Magn Reson | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30077145 |
Characterization of frequency-chirped dynamic nuclear polarization in rotating solids. | Judge PT, Sesti EL, Alaniva N, Saliba EP, Price LE, Gao C, Halbritter T, Sigurdsson ST, Kyei GB, Barnes AB | Journal of magnetic resonance (San Diego, Calif. : 1997) | 32203923 | J Magn Reson | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32203923 |
Dynamic Nuclear Polarization Nuclear Magnetic Resonance in Human Cells Using Fluorescent Polarizing Agents. | Albert BJ, Gao C, Sesti EL, Saliba EP, Alaniva N, Scott FJ, Sigurdsson ST, Barnes AB | Biochemistry | 29924582 | Biochemistry | 2018 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/29924582 |
Instrumentation for cryogenic magic angle spinning dynamic nuclear polarization using 90L of liquid nitrogen per day. | Albert BJ, Pahng SH, Alaniva N, Sesti EL, Rand PW, Saliba EP, Scott FJ, Choi EJ, Barnes AB | Journal of magnetic resonance (San Diego, Calif. : 1997) | 28888182 | J Magn Reson | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28888182 |
Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation. | Albert BJ, Niu A, Ramani R, Marshall GR, Wender PA, Williams RM, Ratner L, Barnes AB, Kyei GB | Scientific reports | 28785069 | Sci Rep | 2017 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/28785069 |
Pulsed Electron Decoupling and Strategies for Time Domain Dynamic Nuclear Polarization with Magic Angle Spinning. | Saliba EP, Sesti EL, Alaniva N, Barnes AB | The journal of physical chemistry letters | 30180584 | J Phys Chem Lett | 2018 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/30180584 |
Fast electron paramagnetic resonance magic angle spinning simulations using analytical powder averaging techniques. | Saliba EP, Barnes AB | The Journal of chemical physics | 31542017 | J Chem Phys | 2019 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/31542017 |
Frequency swept microwaves for hyperfine decoupling and time domain dynamic nuclear polarization. | Hoff DE, Albert BJ, Saliba EP, Scott FJ, Choi EJ, Mardini M, Barnes AB | Solid state nuclear magnetic resonance | 26482131 | Solid State Nucl Magn Reson | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26482131 |
Frequency-agile gyrotron for electron decoupling and pulsed dynamic nuclear polarization. | Scott FJ, Saliba EP, Albert BJ, Alaniva N, Sesti EL, Gao C, Golota NC, Choi EJ, Jagtap AP, Wittmann JJ, Eckardt M, Harneit W, Corzilius B, Th Sigurdsson S, Barnes AB | Journal of magnetic resonance (San Diego, Calif. : 1997) | 29471275 | J Magn Reson | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29471275 |
A versatile custom cryostat for dynamic nuclear polarization supports multiple cryogenic magic angle spinning transmission line probes. | Scott FJ, Alaniva N, Golota NC, Sesti EL, Saliba EP, Price LE, Albert BJ, Chen P, O'Connor RD, Barnes AB | Journal of magnetic resonance (San Diego, Calif. : 1997) | 30342370 | J Magn Reson | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30342370 |
Magic angle spinning NMR with metallized rotors as cylindrical microwave resonators. | Scott FJ, Sesti EL, Choi EJ, Laut AJ, Sirigiri JR, Barnes AB | Magnetic resonance in chemistry : MRC | 29672916 | Magn Reson Chem | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/29672916 |
Magic angle spinning NMR below 6 K with a computational fluid dynamics analysis of fluid flow and temperature gradients. | Sesti EL, Alaniva N, Rand PW, Choi EJ, Albert BJ, Saliba EP, Scott FJ, Barnes AB | Journal of magnetic resonance (San Diego, Calif. : 1997) | 29161649 | J Magn Reson | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/29161649 |
Frequency-chirped dynamic nuclear polarization with magic angle spinning using a frequency-agile gyrotron. | Gao C, Alaniva N, Saliba EP, Sesti EL, Judge PT, Scott FJ, Halbritter T, Sigurdsson ST, Barnes AB | Journal of magnetic resonance (San Diego, Calif. : 1997) | 31525550 | J Magn Reson | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31525550 |
T-REX on-demand redox targeting in live cells. | Parvez S, Long MJ, Lin HY, Zhao Y, Haegele JA, Pham VN, Lee DK, Aye Y | Nature protocols | 27809314 | Nat Protoc | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27809314 |
On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry. | Long MJ, Poganik JR, Aye Y | Journal of the American Chemical Society | 26907082 | J Am Chem Soc | 2016 Mar 23 | https://www.ncbi.nlm.nih.gov/pubmed/26907082 |
Breaking the Fourth Wall: Modulating Quaternary Associations for Protein Regulation and Drug Discovery. | Long MJC, Hnedzko D, Kim BK, Aye Y | Chembiochem : a European journal of chemical biology | 30589188 | Chembiochem | 2019 May 2 | https://www.ncbi.nlm.nih.gov/pubmed/30589188 |
β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling. | Long MJ, Lin HY, Parvez S, Zhao Y, Poganik JR, Huang P, Aye Y | Cell chemical biology | 28736239 | Cell Chem Biol | 2017 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/28736239 |
Getting the Message? Native Reactive Electrophiles Pass Two Out of Three Thresholds to be Bona Fide Signaling Mediators. | Poganik JR, Long MJC, Aye Y | BioEssays : news and reviews in molecular, cellular and developmental biology | 29603288 | Bioessays | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29603288 |
Ube2V2 Is a Rosetta Stone Bridging Redox and Ubiquitin Codes, Coordinating DNA Damage Responses. | Zhao Y, Long MJC, Wang Y, Zhang S, Aye Y | ACS central science | 29532025 | ACS Cent Sci | 2018 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/29532025 |
A generalizable platform for interrogating target- and signal-specific consequences of electrophilic modifications in redox-dependent cell signaling. | Lin HY, Haegele JA, Disare MT, Lin Q, Aye Y | Journal of the American Chemical Society | 25909755 | J Am Chem Soc | 2015 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/25909755 |
Chemical Biology Gateways to Mapping Location, Association, and Pathway Responsivity. | Long MJC, Liu X, Aye Y | Frontiers in chemistry | 30949469 | Front Chem | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30949469 |
REX technologies for profiling and decoding the electrophile signaling axes mediated by Rosetta Stone proteins. | Long MJC, Urul DA, Aye Y | Methods in enzymology | 32046846 | Methods Enzymol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32046846 |
Empowering Global Chemical Biology at the Dawn of the New Decade. | Hoogendoorn S, Aye Y | ACS chemical biology | 32315151 | ACS Chem Biol | 2020 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/32315151 |
Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals. | Poganik JR, Aye Y | Frontiers in aging neuroscience | 32116644 | Front Aging Neurosci | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32116644 |
The mRNA-Binding Protein HuR Is a Kinetically-Privileged Electrophile Sensor. | Poganik JR, Van Hall-Beauvais AK, Long MJC, Disare MT, Zhao Y, Aye Y | Helvetica chimica acta | 34113045 | Helv Chim Acta | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/34113045 |
Substoichiometric hydroxynonenylation of a single protein recapitulates whole-cell-stimulated antioxidant response. | Parvez S, Fu Y, Li J, Long MJ, Lin HY, Lee DK, Hu GS, Aye Y | Journal of the American Chemical Society | 25544059 | J Am Chem Soc | 2015 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/25544059 |
Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis. | Long MJC, Zhao Y, Aye Y | Cell chemical biology | 31836351 | Cell Chem Biol | 2020 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/31836351 |
Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1. | Poganik JR, Long MJC, Disare MT, Liu X, Chang SH, Hla T, Aye Y | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 31665914 | FASEB J | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31665914 |
Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation. | Khatri HR, Bhattarai B, Kaplan W, Li Z, Curtis Long MJ, Aye Y, Nagorny P | Journal of the American Chemical Society | 30802047 | J Am Chem Soc | 2019 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/30802047 |
Neighborhood watch: tools for defining locale-dependent subproteomes and their contextual signaling activities. | Long MJC, Zhao Y, Aye Y | RSC chemical biology | 34458747 | RSC Chem Biol | 2020 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/34458747 |
Akt3 is a privileged first responder in isozyme-specific electrophile response. | Long MJ, Parvez S, Zhao Y, Surya SL, Wang Y, Zhang S, Aye Y | Nature chemical biology | 28114274 | Nat Chem Biol | 2017 Mar | https://www.ncbi.nlm.nih.gov/pubmed/28114274 |
Subcellular Redox Targeting: Bridging in Vitro and in Vivo Chemical Biology. | Long MJ, Poganik JR, Ghosh S, Aye Y | ACS chemical biology | 28068059 | ACS Chem Biol | 2017 Mar 17 | https://www.ncbi.nlm.nih.gov/pubmed/28068059 |
The more the merrier: how homo-oligomerization alters the interactome and function of ribonucleotide reductase. | Long MJC, Van Hall-Beauvais A, Aye Y | Current opinion in chemical biology | 31734537 | Curr Opin Chem Biol | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31734537 |
Privileged Electrophile Sensors: A Resource for Covalent Drug Development. | Long MJC, Aye Y | Cell chemical biology | 28648380 | Cell Chem Biol | 2017 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/28648380 |
Proteomics and Beyond: Cell Decision-Making Shaped by Reactive Electrophiles. | Liu X, Long MJC, Aye Y | Trends in biochemical sciences | 30327250 | Trends Biochem Sci | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30327250 |
Weighing up the Selenocysteome Uncovers New Sec-rets. | Poganik JR, Aye Y | Cell chemical biology | 30445052 | Cell Chem Biol | 2018 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/30445052 |
The Die Is Cast: Precision Electrophilic Modifications Contribute to Cellular Decision Making. | Long MJC, Aye Y | Chemical research in toxicology | 27617777 | Chem Res Toxicol | 2016 Oct 17 | https://www.ncbi.nlm.nih.gov/pubmed/27617777 |
Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3. | Fu Y, Long MJC, Wisitpitthaya S, Inayat H, Pierpont TM, Elsaid IM, Bloom JC, Ortega J, Weiss RS, Aye Y | Nature chemical biology | 30150681 | Nat Chem Biol | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30150681 |
Genie in a bottle: controlled release helps tame natural polypharmacology? | Long MJ, Liu X, Aye Y | Current opinion in chemical biology | 30913473 | Curr Opin Chem Biol | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30913473 |
Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor. | Surya SL, Long MJC, Urul DA, Zhao Y, Mercer EJ, EIsaid IM, Evans T, Aye Y | ACS chemical biology | 29397684 | ACS Chem Biol | 2018 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/29397684 |
Redox Signaling by Reactive Electrophiles and Oxidants. | Parvez S, Long MJC, Poganik JR, Aye Y | Chemical reviews | 30148624 | Chem Rev | 2018 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/30148624 |
Single-Protein-Specific Redox Targeting in Live Mammalian Cells and C. elegans. | Van Hall-Beauvais A, Zhao Y, Urul DA, Long MJC, Aye Y | Current protocols in chemical biology | 30085412 | Curr Protoc Chem Biol | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30085412 |
Cladribine and Fludarabine Nucleotides Induce Distinct Hexamers Defining a Common Mode of Reversible RNR Inhibition. | Wisitpitthaya S, Zhao Y, Long MJ, Li M, Fletcher EA, Blessing WA, Weiss RS, Aye Y | ACS chemical biology | 27159113 | ACS Chem Biol | 2016 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/27159113 |
Getting the Right Grip? How Understanding Electrophile Selectivity Profiles Could Illuminate Our Understanding of Redox Signaling. | Long MJC, Wang L, Aye Y | Antioxidants & redox signaling | 31578876 | Antioxid Redox Signal | 2020 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/31578876 |
Distribution shapes govern the discovery of predictive models for gene regulation. | Munsky B, Li G, Fox ZR, Shepherd DP, Neuert G | Proceedings of the National Academy of Sciences of the United States of America | 29959206 | Proc Natl Acad Sci U S A | 2018 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/29959206 |
Finite state projection based bounds to compare chemical master equation models using single-cell data. | Fox Z, Neuert G, Munsky B | The Journal of chemical physics | 27544081 | J Chem Phys | 2016 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/27544081 |
Modelling patient drug exposure profiles in vitro to narrow the valley of death. | Leasure CS, Neuert G | Nature reviews bioengineering | 38873361 | Nat Rev Bioeng | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38873361 |
Diverse Cell Stimulation Kinetics Identify Predictive Signal Transduction Models. | Jashnsaz H, Fox ZR, Hughes JJ, Li G, Munsky B, Neuert G | iScience | 33083733 | iScience | 2020 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/33083733 |
Optimal Design of Single-Cell Experiments within Temporally Fluctuating Environments. | Fox ZR, Neuert G, Munsky B | Complexity | 32982137 | Complexity | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32982137 |
Phenotypic consequences of logarithmic signaling in MAPK stress response. | Jashnsaz H, Neuert G | bioRxiv : the preprint server for biology | 38106069 | bioRxiv | 2023 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/38106069 |
Generating kinetic environments to study dynamic cellular processes in single cells. | Thiemicke A, Jashnsaz H, Li G, Neuert G | Scientific reports | 31300695 | Sci Rep | 2019 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/31300695 |
Multiplex RNA single molecule FISH of inducible mRNAs in single yeast cells. | Li G, Neuert G | Scientific data | 31209217 | Sci Data | 2019 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/31209217 |
A rate threshold mechanism regulates MAPK stress signaling and survival. | Johnson AN, Li G, Jashnsaz H, Thiemicke A, Kesler BK, Rogers DC, Neuert G | Proceedings of the National Academy of Sciences of the United States of America | 33443180 | Proc Natl Acad Sci U S A | 2021 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/33443180 |
Kinetics of osmotic stress regulate a cell fate switch of cell survival. | Thiemicke A, Neuert G | Science advances | 33608274 | Sci Adv | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33608274 |
Rate thresholds in cell signaling have functional and phenotypic consequences in non-linear time-dependent environments. | Thiemicke A, Neuert G | Frontiers in cell and developmental biology | 37025183 | Front Cell Dev Biol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37025183 |
Automated cell boundary and 3D nuclear segmentation of cells in suspension. | Kesler B, Li G, Thiemicke A, Venkat R, Neuert G | Scientific reports | 31308458 | Sci Rep | 2019 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/31308458 |
Integrating single-molecule experiments and discrete stochastic models to understand heterogeneous gene transcription dynamics. | Munsky B, Fox Z, Neuert G | Methods (San Diego, Calif.) | 26079925 | Methods | 2015 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/26079925 |
From analog to digital models of gene regulation. | Munsky B, Neuert G | Physical biology | 26086470 | Phys Biol | 2015 Jun 18 | https://www.ncbi.nlm.nih.gov/pubmed/26086470 |
TrueSpot: A robust automated tool for quantifying signal puncta in fluorescent imaging. | Hospelhorn BG, Kesler BK, Jashnsaz H, Neuert G | bioRxiv : the preprint server for biology | 39868229 | bioRxiv | 2025 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/39868229 |
Chemoselective ratiometric imaging of protein S-sulfenylation. | Tom CTMB, Crellin JE, Motiwala HF, Stone MB, Davda D, Walker W, Kuo YH, Hernandez JL, Labby KJ, Gomez-Rodriguez L, Jenkins PM, Veatch SL, Martin BR | Chemical communications (Cambridge, England) | 28613292 | Chem Commun (Camb) | 2017 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/28613292 |
Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2). | Won SJ, Davda D, Labby KJ, Hwang SY, Pricer R, Majmudar JD, Armacost KA, Rodriguez LA, Rodriguez CL, Chong FS, Torossian KA, Palakurthi J, Hur ES, Meagher JL, Brooks CL 3rd, Stuckey JA, Martin BR | ACS chemical biology | 27748579 | ACS Chem Biol | 2016 Dec 16 | https://www.ncbi.nlm.nih.gov/pubmed/27748579 |
Variable-Velocity Traveling-Wave Ion Mobility Separation Enhancing Peak Capacity for Data-Independent Acquisition Proteomics. | Haynes SE, Polasky DA, Dixit SM, Majmudar JD, Neeson K, Ruotolo BT, Martin BR | Analytical chemistry | 28471653 | Anal Chem | 2017 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/28471653 |
Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling. | Motiwala HF, Kuo YH, Stinger BL, Palfey BA, Martin BR | Journal of the American Chemical Society | 31881155 | J Am Chem Soc | 2020 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/31881155 |
Global Analysis of Palmitoylated Proteins in Toxoplasma gondii. | Foe IT, Child MA, Majmudar JD, Krishnamurthy S, van der Linden WA, Ward GE, Martin BR, Bogyo M | Cell host & microbe | 26468752 | Cell Host Microbe | 2015 Oct 14 | https://www.ncbi.nlm.nih.gov/pubmed/26468752 |
Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes. | Xu H, Majmudar JD, Davda D, Ghanakota P, Kim KH, Carlson HA, Showalter HD, Martin BR, Amidon GL | Molecular pharmaceutics | 26262434 | Mol Pharm | 2015 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/26262434 |
Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle. | Won SJ, Martin BR | ACS chemical biology | 29733200 | ACS Chem Biol | 2018 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/29733200 |
APT2 Inhibition Restores Scribble Localization and S-Palmitoylation in Snail-Transformed Cells. | Hernandez JL, Davda D, Cheung See Kit M, Majmudar JD, Won SJ, Gang M, Pasupuleti SC, Choi AI, Bartkowiak CM, Martin BR | Cell chemical biology | 28065656 | Cell Chem Biol | 2017 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/28065656 |
Activated G Protein Gαs Samples Multiple Endomembrane Compartments. | Martin BR, Lambert NA | The Journal of biological chemistry | 27528603 | J Biol Chem | 2016 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/27528603 |
Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly. | ElAzzouny M, Tom CT, Evans CR, Olson LL, Tanga MJ, Gallagher KA, Martin BR, Burant CF | The Journal of biological chemistry | 28188288 | J Biol Chem | 2017 Mar 24 | https://www.ncbi.nlm.nih.gov/pubmed/28188288 |
Harnessing Redox Cross-Reactivity To Profile Distinct Cysteine Modifications. | Majmudar JD, Konopko AM, Labby KJ, Tom CT, Crellin JE, Prakash A, Martin BR | Journal of the American Chemical Society | 26780921 | J Am Chem Soc | 2016 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/26780921 |
Correlated S-palmitoylation profiling of Snail-induced epithelial to mesenchymal transition. | Hernandez JL, Davda D, Majmudar JD, Won SJ, Prakash A, Choi AI, Martin BR | Molecular bioSystems | 27030425 | Mol Biosyst | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27030425 |
Targeted Annotation of S-Sulfonylated Peptides by Selective Infrared Multiphoton Dissociation Mass Spectrometry. | Borotto NB, McClory PJ, Martin BR, Håkansson K | Analytical chemistry | 28708386 | Anal Chem | 2017 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/28708386 |
DIA-SIFT: A Precursor and Product Ion Filter for Accurate Stable Isotope Data-Independent Acquisition Proteomics. | Haynes SE, Majmudar JD, Martin BR | Analytical chemistry | 29989796 | Anal Chem | 2018 Aug 7 | https://www.ncbi.nlm.nih.gov/pubmed/29989796 |
Affinity-Based Selectivity Profiling of an In-Class Selective Competitive Inhibitor of Acyl Protein Thioesterase 2. | Won SJ, Eschweiler JD, Majmudar JD, Chong FS, Hwang SY, Ruotolo BT, Martin BR | ACS medicinal chemistry letters | 28197315 | ACS Med Chem Lett | 2017 Feb 9 | https://www.ncbi.nlm.nih.gov/pubmed/28197315 |
Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation. | Zhao D, Yin Z, Soellner MB, Martin BR | Cell chemical biology | 33730553 | Cell Chem Biol | 2021 Aug 19 | https://www.ncbi.nlm.nih.gov/pubmed/33730553 |
Profiling Protein S-Sulfination with Maleimide-Linked Probes. | Kuo YH, Konopko AM, Borotto NB, Majmudar JD, Haynes SE, Martin BR | Chembiochem : a European journal of chemical biology | 28809078 | Chembiochem | 2017 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/28809078 |
HDAC8 Substrates Identified by Genetically Encoded Active Site Photocrosslinking. | Lopez JE, Haynes SE, Majmudar JD, Martin BR, Fierke CA | Journal of the American Chemical Society | 29035536 | J Am Chem Soc | 2017 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/29035536 |
Protein depalmitoylases. | Won SJ, Cheung See Kit M, Martin BR | Critical reviews in biochemistry and molecular biology | 29239216 | Crit Rev Biochem Mol Biol | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29239216 |
Enrichment of S-Palmitoylated Proteins for Mass Spectrometry Analysis. | Cheung See Kit M, Martin BR | Methods in molecular biology (Clifton, N.J.) | 31152396 | Methods Mol Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31152396 |
Free Radical Initiated Peptide Sequencing for Direct Site Localization of Sulfation and Phosphorylation with Negative Ion Mode Mass Spectrometry. | Borotto NB, Ileka KM, Tom CATMB, Martin BR, Håkansson K | Analytical chemistry | 30063332 | Anal Chem | 2018 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/30063332 |
Placing and shaping liposomes with reconfigurable DNA nanocages. | Zhang Z, Yang Y, Pincet F, Llaguno MC, Lin C | Nature chemistry | 28644472 | Nat Chem | 2017 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/28644472 |
DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells. | Williams ND, Landajuela A, Kasula RK, Zhou W, Powell JT, Xi Z, Isaacs FJ, Berro J, Toomre D, Karatekin E, Lin C | Nano letters | 33164530 | Nano Lett | 2020 Dec 9 | https://www.ncbi.nlm.nih.gov/pubmed/33164530 |
DNA Origami Post-Processing by CRISPR-Cas12a. | Xiong Q, Xie C, Zhang Z, Liu L, Powell JT, Shen Q, Lin C | Angewandte Chemie (International ed. in English) | 31883145 | Angew Chem Int Ed Engl | 2020 Mar 2 | https://www.ncbi.nlm.nih.gov/pubmed/31883145 |
FisB relies on homo-oligomerization and lipid binding to catalyze membrane fission in bacteria. | Landajuela A, Braun M, Rodrigues CDA, Martínez-Calvo A, Doan T, Horenkamp F, Andronicos A, Shteyn V, Williams ND, Lin C, Wingreen NS, Rudner DZ, Karatekin E | PLoS biology | 34185788 | PLoS Biol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34185788 |
Engineering Lipid Membranes with Programmable DNA Nanostructures. | Shen Q, Grome MW, Yang Y, Lin C | Advanced biosystems | 31934608 | Adv Biosyst | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31934608 |
A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement. | Fisher PDE, Shen Q, Akpinar B, Davis LK, Chung KKH, Baddeley D, Šarić A, Melia TJ, Hoogenboom BW, Lin C, Lusk CP | ACS nano | 29350911 | ACS Nano | 2018 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/29350911 |
Vesicle Tubulation with Self-Assembling DNA Nanosprings. | Grome MW, Zhang Z, Pincet F, Lin C | Angewandte Chemie (International ed. in English) | 29575478 | Angew Chem Int Ed Engl | 2018 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/29575478 |
Stiffness and Membrane Anchor Density Modulate DNA-Nanospring-Induced Vesicle Tubulation. | Grome MW, Zhang Z, Lin C | ACS applied materials & interfaces | 31252462 | ACS Appl Mater Interfaces | 2019 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/31252462 |
A programmable DNA-origami platform for studying lipid transfer between bilayers. | Bian X, Zhang Z, Xiong Q, De Camilli P, Lin C | Nature chemical biology | 31320758 | Nat Chem Biol | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31320758 |
DNA Origami Rotaxanes: Tailored Synthesis and Controlled Structure Switching. | Powell JT, Akhuetie-Oni BO, Zhang Z, Lin C | Angewandte Chemie (International ed. in English) | 27527591 | Angew Chem Int Ed Engl | 2016 Sep 12 | https://www.ncbi.nlm.nih.gov/pubmed/27527591 |
Sorting sub-150-nm liposomes of distinct sizes by DNA-brick-assisted centrifugation. | Yang Y, Wu Z, Wang L, Zhou K, Xia K, Xiong Q, Liu L, Zhang Z, Chapman ER, Xiong Y, Melia TJ, Karatekin E, Gu H, Lin C | Nature chemistry | 33785892 | Nat Chem | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33785892 |
Directing reconfigurable DNA nanoarrays. | Yang Y, Lin C | Science (New York, N.Y.) | 28751594 | Science | 2017 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/28751594 |
Fluorogenic DNA-PAINT for faster, low-background super-resolution imaging. | Chung KKH, Zhang Z, Kidd P, Zhang Y, Williams ND, Rollins B, Yang Y, Lin C, Baddeley D, Bewersdorf J | Nature methods | 35501386 | Nat Methods | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35501386 |
A systematic comparison of error correction enzymes by next-generation sequencing. | Lubock NB, Zhang D, Sidore AM, Church GM, Kosuri S | Nucleic acids research | 28911123 | Nucleic Acids Res | 2017 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/28911123 |
Dissection of c-AMP Response Element Architecture by Using Genomic and Episomal Massively Parallel Reporter Assays. | Davis JE, Insigne KD, Jones EM, Hastings QA, Boldridge WC, Kosuri S | Cell systems | 32603702 | Cell Syst | 2020 Jul 22 | https://www.ncbi.nlm.nih.gov/pubmed/32603702 |
Systematic Dissection of Sequence Elements Controlling σ70 Promoters Using a Genomically Encoded Multiplexed Reporter Assay in Escherichia coli. | Urtecho G, Tripp AD, Insigne KD, Kim H, Kosuri S | Biochemistry | 29388765 | Biochemistry | 2019 Mar 19 | https://www.ncbi.nlm.nih.gov/pubmed/29388765 |
Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems. | Yu TC, Liu WL, Brinck MS, Davis JE, Shek J, Bower G, Einav T, Insigne KD, Phillips R, Kosuri S, Urtecho G | Nature communications | 33436562 | Nat Commun | 2021 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/33436562 |
Multiplexed gene synthesis in emulsions for exploring protein functional landscapes. | Plesa C, Sidore AM, Lubock NB, Zhang D, Kosuri S | Science (New York, N.Y.) | 29301959 | Science | 2018 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/29301959 |
A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions. | Chong R, Insigne KD, Yao D, Burghard CP, Wang J, Hsiao YE, Jones EM, Goodman DB, Xiao X, Kosuri S | Molecular cell | 30503770 | Mol Cell | 2019 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/30503770 |
Highly parallel genome variant engineering with CRISPR-Cas9. | Sadhu MJ, Bloom JS, Day L, Siegel JJ, Kosuri S, Kruglyak L | Nature genetics | 29632376 | Nat Genet | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29632376 |
Structural and functional characterization of G protein-coupled receptors with deep mutational scanning. | Jones EM, Lubock NB, Venkatakrishnan AJ, Wang J, Tseng AM, Paggi JM, Latorraca NR, Cancilla D, Satyadi M, Davis JE, Babu MM, Dror RO, Kosuri S | eLife | 33084570 | Elife | 2020 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/33084570 |
Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross. | Renganaath K, Chong R, Day L, Kosuri S, Kruglyak L, Albert FW | eLife | 33179598 | Elife | 2020 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/33179598 |
A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing. | Jones EM, Jajoo R, Cancilla D, Lubock NB, Wang J, Satyadi M, Chong R, de March C, Bloom JS, Matsunami H, Kosuri S | Cell systems | 30904378 | Cell Syst | 2019 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/30904378 |
Metagenomic mining of regulatory elements enables programmable species-selective gene expression. | Johns NI, Gomes ALC, Yim SS, Yang A, Blazejewski T, Smillie CS, Smith MB, Alm EJ, Kosuri S, Wang HH | Nature methods | 30052624 | Nat Methods | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/30052624 |
DropSynth 2.0: high-fidelity multiplexed gene synthesis in emulsions. | Sidore AM, Plesa C, Samson JA, Lubock NB, Kosuri S | Nucleic acids research | 32692349 | Nucleic Acids Res | 2020 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/32692349 |
A multiplexed bacterial two-hybrid for rapid characterization of protein-protein interactions and iterative protein design. | Boldridge WC, Ljubetič A, Kim H, Lubock N, Szilágyi D, Lee J, Brodnik A, Jerala R, Kosuri S | Nature communications | 37532706 | Nat Commun | 2023 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/37532706 |
Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network. | Longabaugh WJR, Zeng W, Zhang JA, Hosokawa H, Jansen CS, Li L, Romero-Wolf M, Liu P, Kueh HY, Mortazavi A, Rothenberg EV | Proceedings of the National Academy of Sciences of the United States of America | 28584128 | Proc Natl Acad Sci U S A | 2017 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/28584128 |
Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss. | Hernandez MX, Jiang S, Cole TA, Chu SH, Fonseca MI, Fang MJ, Hohsfield LA, Torres MD, Green KN, Wetsel RA, Mortazavi A, Tenner AJ | Molecular neurodegeneration | 28923083 | Mol Neurodegener | 2017 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/28923083 |
Comparative genomics of Steinernema reveals deeply conserved gene regulatory networks. | Dillman AR, Macchietto M, Porter CF, Rogers A, Williams B, Antoshechkin I, Lee MM, Goodwin Z, Lu X, Lewis EE, Goodrich-Blair H, Stock SP, Adams BJ, Sternberg PW, Mortazavi A | Genome biology | 26392177 | Genome Biol | 2015 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/26392177 |
Single-nucleus RNA-seq of differentiating human myoblasts reveals the extent of fate heterogeneity. | Zeng W, Jiang S, Kong X, El-Ali N, Ball AR Jr, Ma CI, Hashimoto N, Yokomori K, Mortazavi A | Nucleic acids research | 27566152 | Nucleic Acids Res | 2016 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/27566152 |
Regeneration of fat cells from myofibroblasts during wound healing. | Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, Hsi TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, Wang A, Supapannachart RJ, Lee HL, Lim CH, Nace A, Guo A, Treffeisen E, Andl T, Ramirez RN, Murad R, Offermanns S, Metzger D, Chambon P, Widgerow AD, Tuan TL, Mortazavi A, Gupta RK, Hamilton BA, Millar SE, Seale P, Pear WS, Lazar MA, Cotsarelis G | Science (New York, N.Y.) | 28059714 | Science | 2017 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/28059714 |
Adapting the Smart-seq2 Protocol for Robust Single Worm RNA-seq. | Serra L, Chang DZ, Macchietto M, Williams K, Murad R, Lu D, Dillman AR, Mortazavi A | Bio-protocol | 29564372 | Bio Protoc | 2018 Feb 20 | https://www.ncbi.nlm.nih.gov/pubmed/29564372 |
Better together: multiplexing samples to improve the preparation and reliability of gene expression studies. | Mortazavi A | Nature methods | 25825835 | Nat Methods | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25825835 |
Comparative Transcriptomics of Steinernema and Caenorhabditis Single Embryos Reveals Orthologous Gene Expression Convergence during Late Embryogenesis. | Macchietto M, Angdembey D, Heidarpour N, Serra L, Rodriguez B, El-Ali N, Mortazavi A | Genome biology and evolution | 29048526 | Genome Biol Evol | 2017 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/29048526 |
Dynamic Gene Regulatory Networks of Human Myeloid Differentiation. | Ramirez RN, El-Ali NC, Mager MA, Wyman D, Conesa A, Mortazavi A | Cell systems | 28365152 | Cell Syst | 2017 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/28365152 |
Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication. | Ou K, Yu M, Moss NG, Wang YJ, Wang AW, Nguyen SC, Jiang C, Feleke E, Kameswaran V, Joyce EF, Naji A, Glaser B, Avrahami D, Kaestner KH | The Journal of clinical investigation | 30352048 | J Clin Invest | 2019 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/30352048 |
Integrating ChIP-seq with other functional genomics data. | Jiang S, Mortazavi A | Briefings in functional genomics | 29579165 | Brief Funct Genomics | 2018 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/29579165 |
Activated entomopathogenic nematode infective juveniles release lethal venom proteins. | Lu D, Macchietto M, Chang D, Barros MM, Baldwin J, Mortazavi A, Dillman AR | PLoS pathogens | 28426766 | PLoS Pathog | 2017 Apr | https://www.ncbi.nlm.nih.gov/pubmed/28426766 |
A survey of best practices for RNA-seq data analysis. | Conesa A, Madrigal P, Tarazona S, Gomez-Cabrero D, Cervera A, McPherson A, Szcześniak MW, Gaffney DJ, Elo LL, Zhang X, Mortazavi A | Genome biology | 26813401 | Genome Biol | 2016 Jan 26 | https://www.ncbi.nlm.nih.gov/pubmed/26813401 |
Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth. | Wallace J, Hu R, Mosbruger TL, Dahlem TJ, Stephens WZ, Rao DS, Round JL, O'Connell RM | PloS one | 27081855 | PLoS One | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27081855 |
Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis. | Lochhead RB, Zachary JF, Dalla Rosa L, Ma Y, Weis JH, O'Connell RM, Weis JJ | PloS one | 26252010 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26252010 |
Adaptive immunity induces mutualism between commensal eukaryotes. | Ost KS, O'Meara TR, Stephens WZ, Chiaro T, Zhou H, Penman J, Bell R, Catanzaro JR, Song D, Singh S, Call DH, Hwang-Wong E, Hanson KE, Valentine JF, Christensen KA, O'Connell RM, Cormack B, Ibrahim AS, Palm NW, Noble SM, Round JL | Nature | 34262174 | Nature | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34262174 |
Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis. | Zhao JL, Ma C, O'Connell RM, Mehta A, DiLoreto R, Heath JR, Baltimore D | Cell stem cell | 24561084 | Cell Stem Cell | 2014 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/24561084 |
A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice. | Chiaro TR, Soto R, Zac Stephens W, Kubinak JL, Petersen C, Gogokhia L, Bell R, Delgado JC, Cox J, Voth W, Brown J, Stillman DJ, O'Connell RM, Tebo AE, Round JL | Science translational medicine | 28275154 | Sci Transl Med | 2017 Mar 8 | https://www.ncbi.nlm.nih.gov/pubmed/28275154 |
MicroRNA 155 and viral-induced neuroinflammation. | Dickey LL, Hanley TM, Huffaker TB, Ramstead AG, O'Connell RM, Lane TE | Journal of neuroimmunology | 28139244 | J Neuroimmunol | 2017 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/28139244 |
T cell-mediated regulation of the microbiota protects against obesity. | Petersen C, Bell R, Klag KA, Lee SH, Soto R, Ghazaryan A, Buhrke K, Ekiz HA, Ost KS, Boudina S, O'Connell RM, Cox JE, Villanueva CJ, Stephens WZ, Round JL | Science (New York, N.Y.) | 31346040 | Science | 2019 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/31346040 |
Clec12a controls colitis by tempering inflammation and restricting expansion of specific commensals. | Chiaro TR, Greenewood M, Bauer KM, Ost KS, Stephen-Victor E, Murphy M, Weis AM, Nelson MC, Hill JH, Bell R, Voth W, Jackson T, Klag KA, O'Connell RM, Zac Stephens W, Round JL | Cell host & microbe | 39788099 | Cell Host Microbe | 2025 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/39788099 |
MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health. | Kubinak JL, Petersen C, Stephens WZ, Soto R, Bake E, O'Connell RM, Round JL | Cell host & microbe | 25620548 | Cell Host Microbe | 2015 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/25620548 |
MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection. | Kubinak JL, Stephens WZ, Soto R, Petersen C, Chiaro T, Gogokhia L, Bell R, Ajami NJ, Petrosino JF, Morrison L, Potts WK, Jensen PE, O'Connell RM, Round JL | Nature communications | 26494419 | Nat Commun | 2015 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/26494419 |
Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli. | Alexander M, Ramstead AG, Bauer KM, Lee SH, Runtsch MC, Wallace J, Huffaker TB, Larsen DK, Tolmachova T, Seabra MC, Round JL, Ward DM, O'Connell RM | Journal of immunology (Baltimore, Md. : 1950) | 28978688 | J Immunol | 2017 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/28978688 |
MicroRNAs and acute myeloid leukemia: therapeutic implications and emerging concepts. | Wallace JA, O'Connell RM | Blood | 28751524 | Blood | 2017 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/28751524 |
MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi. | Lochhead RB, Ma Y, Zachary JF, Baltimore D, Zhao JL, Weis JH, O'Connell RM, Weis JJ | PLoS pathogens | 24967703 | PLoS Pathog | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24967703 |
miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation. | Hu R, Kagele DA, Huffaker TB, Runtsch MC, Alexander M, Liu J, Bake E, Su W, Williams MA, Rao DS, Möller T, Garden GA, Round JL, O'Connell RM | Immunity | 25367574 | Immunity | 2014 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/25367574 |
miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response. | Wallace JA, Kagele DA, Eiring AM, Kim CN, Hu R, Runtsch MC, Alexander M, Huffaker TB, Lee SH, Patel AB, Mosbruger TL, Voth WP, Rao DS, Miles RR, Round JL, Deininger MW, O'Connell RM | Blood | 28432220 | Blood | 2017 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/28432220 |
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis. | Gogokhia L, Buhrke K, Bell R, Hoffman B, Brown DG, Hanke-Gogokhia C, Ajami NJ, Wong MC, Ghazaryan A, Valentine JF, Porter N, Martens E, O'Connell R, Jacob V, Scherl E, Crawford C, Stephens WZ, Casjens SR, Longman RS, Round JL | Cell host & microbe | 30763538 | Cell Host Microbe | 2019 Feb 13 | https://www.ncbi.nlm.nih.gov/pubmed/30763538 |
Colitis reduces active social engagement in mice and is ameliorated by supplementation with human microbiota members. | Brown DG, Murphy M, Cadeddu R, Bell R, Weis A, Chiaro T, Klag K, Morgan J, Coon H, Stephens WZ, Bortolato M, Round JL | Nature communications | 38553486 | Nat Commun | 2024 Mar 30 | https://www.ncbi.nlm.nih.gov/pubmed/38553486 |
Choosing the right pharmacotherapeutic strategy for HIV maintenance in patients with alcohol addiction. | Kodidela S, Kumar S | Expert opinion on pharmacotherapy | 30724618 | Expert Opin Pharmacother | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30724618 |
Characterizing RNA structures in vitro and in vivo with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq). | Watters KE, Yu AM, Strobel EJ, Settle AH, Lucks JB | Methods (San Diego, Calif.) | 27064082 | Methods | 2016 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/27064082 |
Simultaneous characterization of cellular RNA structure and function with in-cell SHAPE-Seq. | Watters KE, Abbott TR, Lucks JB | Nucleic acids research | 26350218 | Nucleic Acids Res | 2016 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/26350218 |
Characterizing the Structure-Function Relationship of a Naturally Occurring RNA Thermometer. | Meyer S, Carlson PD, Lucks JB | Biochemistry | 29172455 | Biochemistry | 2017 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/29172455 |
Computationally reconstructing cotranscriptional RNA folding from experimental data reveals rearrangement of non-native folding intermediates. | Yu AM, Gasper PM, Cheng L, Lai LB, Kaur S, Gopalan V, Chen AA, Lucks JB | Molecular cell | 33453165 | Mol Cell | 2021 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/33453165 |
Distributed biotin-streptavidin transcription roadblocks for mapping cotranscriptional RNA folding. | Strobel EJ, Watters KE, Nedialkov Y, Artsimovitch I, Lucks JB | Nucleic acids research | 28398514 | Nucleic Acids Res | 2017 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/28398514 |
SHAPE-Seq 2.0: systematic optimization and extension of high-throughput chemical probing of RNA secondary structure with next generation sequencing. | Loughrey D, Watters KE, Settle AH, Lucks JB | Nucleic acids research | 25303992 | Nucleic Acids Res | 2014 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/25303992 |
SnapShot: RNA Structure Probing Technologies. | Carlson PD, Evans ME, Yu AM, Strobel EJ, Lucks JB | Cell | 30290145 | Cell | 2018 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/30290145 |
Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements. | Watters KE, Choudhary K, Aviran S, Lucks JB, Perry KL, Thompson JR | Nucleic acids research | 29294088 | Nucleic Acids Res | 2018 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/29294088 |
RNA systems biology: uniting functional discoveries and structural tools to understand global roles of RNAs. | Strobel EJ, Watters KE, Loughrey D, Lucks JB | Current opinion in biotechnology | 27132125 | Curr Opin Biotechnol | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27132125 |
Using in-cell SHAPE-Seq and simulations to probe structure-function design principles of RNA transcriptional regulators. | Takahashi MK, Watters KE, Gasper PM, Abbott TR, Carlson PD, Chen AA, Lucks JB | RNA (New York, N.Y.) | 27103533 | RNA | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27103533 |
Mapping RNA Structure In Vitro with SHAPE Chemistry and Next-Generation Sequencing (SHAPE-Seq). | Watters KE, Lucks JB | Methods in molecular biology (Clifton, N.J.) | 27665597 | Methods Mol Biol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27665597 |
DUETT quantitatively identifies known and novel events in nascent RNA structural dynamics from chemical probing data. | Xue AY, Yu AM, Lucks JB, Bagheri N | Bioinformatics (Oxford, England) | 31389563 | Bioinformatics | 2019 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/31389563 |
Computational design of three-dimensional RNA structure and function. | Yesselman JD, Eiler D, Carlson ED, Gotrik MR, d'Aquino AE, Ooms AN, Kladwang W, Carlson PD, Shi X, Costantino DA, Herschlag D, Lucks JB, Jewett MC, Kieft JS, Das R | Nature nanotechnology | 31427748 | Nat Nanotechnol | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31427748 |
Cotranscriptional folding of a riboswitch at nucleotide resolution. | Watters KE, Strobel EJ, Yu AM, Lis JT, Lucks JB | Nature structural & molecular biology | 27798597 | Nat Struct Mol Biol | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27798597 |
High-throughput determination of RNA structures. | Strobel EJ, Yu AM, Lucks JB | Nature reviews. Genetics | 30054568 | Nat Rev Genet | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30054568 |
A ligand-gated strand displacement mechanism for ZTP riboswitch transcription control. | Strobel EJ, Cheng L, Berman KE, Carlson PD, Lucks JB | Nature chemical biology | 31636437 | Nat Chem Biol | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31636437 |
Inhibiting the Evolution of Antibiotic Resistance. | Ragheb MN, Thomason MK, Hsu C, Nugent P, Gage J, Samadpour AN, Kariisa A, Merrikh CN, Miller SI, Sherman DR, Merrikh H | Molecular cell | 30449724 | Mol Cell | 2019 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/30449724 |
Spatial and Temporal Control of Evolution through Replication-Transcription Conflicts. | Merrikh H | Trends in microbiology | 28216294 | Trends Microbiol | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28216294 |
Crystal structure of a membrane-bound O-acyltransferase. | Ma D, Wang Z, Merrikh CN, Lang KS, Lu P, Li X, Merrikh H, Rao Z, Xu W | Nature | 30283133 | Nature | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30283133 |
Gene inversion potentiates bacterial evolvability and virulence. | Merrikh CN, Merrikh H | Nature communications | 30405125 | Nat Commun | 2018 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/30405125 |
Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis. | Lang KS, Hall AN, Merrikh CN, Ragheb M, Tabakh H, Pollock AJ, Woodward JJ, Dreifus JE, Merrikh H | Cell | 28802046 | Cell | 2017 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/28802046 |
The B. subtilis Accessory Helicase PcrA Facilitates DNA Replication through Transcription Units. | Merrikh CN, Brewer BJ, Merrikh H | PLoS genetics | 26070154 | PLoS Genet | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26070154 |
Replication Restart after Replication-Transcription Conflicts Requires RecA in Bacillus subtilis. | Million-Weaver S, Samadpour AN, Merrikh H | Journal of bacteriology | 25939832 | J Bacteriol | 2015 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25939832 |
Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts. | Lang KS, Merrikh H | Cell reports | 33657379 | Cell Rep | 2021 Mar 2 | https://www.ncbi.nlm.nih.gov/pubmed/33657379 |
The Accelerated Evolution of Lagging Strand Genes Is Independent of Sequence Context. | Merrikh CN, Weiss E, Merrikh H | Genome biology and evolution | 28039230 | Genome Biol Evol | 2016 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/28039230 |
The bacterial replisome has factory-like localization. | Mangiameli SM, Cass JA, Merrikh H, Wiggins PA | Current genetics | 29632994 | Curr Genet | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29632994 |
The Clash of Macromolecular Titans: Replication-Transcription Conflicts in Bacteria. | Lang KS, Merrikh H | Annual review of microbiology | 29856930 | Annu Rev Microbiol | 2018 Sep 8 | https://www.ncbi.nlm.nih.gov/pubmed/29856930 |
DNA gyrase activity regulates DnaA-dependent replication initiation in Bacillus subtilis. | Samadpour AN, Merrikh H | Molecular microbiology | 29396913 | Mol Microbiol | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29396913 |
An underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis. | Million-Weaver S, Samadpour AN, Moreno-Habel DA, Nugent P, Brittnacher MJ, Weiss E, Hayden HS, Miller SI, Liachko I, Merrikh H | Proceedings of the National Academy of Sciences of the United States of America | 25713353 | Proc Natl Acad Sci U S A | 2015 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/25713353 |
Current outcomes when optimizing 'standard' sample preparation for single-particle cryo-EM. | Carragher B, Cheng Y, Frost A, Glaeser RM, Lander GC, Nogales E, Wang HW | Journal of microscopy | 31553060 | J Microsc | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31553060 |
Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins. | Kalia R, Frost A | Molecular biology of the cell | 31365329 | Mol Biol Cell | 2019 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/31365329 |
Membrane constriction and thinning by sequential ESCRT-III polymerization. | Nguyen HC, Talledge N, McCullough J, Sharma A, Moss FR 3rd, Iwasa JH, Vershinin MD, Sundquist WI, Frost A | Nature structural & molecular biology | 32251413 | Nat Struct Mol Biol | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32251413 |
Structural and functional studies of membrane remodeling machines. | Kalia R, Talledge N, Frost A | Methods in cell biology | 25997348 | Methods Cell Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25997348 |
In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing. | Osuna BA, Howard CJ, Kc S, Frost A, Weinberg DE | eLife | 28718767 | Elife | 2017 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/28718767 |
Structure and membrane remodeling activity of ESCRT-III helical polymers. | McCullough J, Clippinger AK, Talledge N, Skowyra ML, Saunders MG, Naismith TV, Colf LA, Afonine P, Arthur C, Sundquist WI, Hanson PI, Frost A | Science (New York, N.Y.) | 26634441 | Science | 2015 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/26634441 |
LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. | Gu M, LaJoie D, Chen OS, von Appen A, Ladinsky MS, Redd MJ, Nikolova L, Bjorkman PJ, Sundquist WI, Ullman KS, Frost A | Proceedings of the National Academy of Sciences of the United States of America | 28242692 | Proc Natl Acad Sci U S A | 2017 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/28242692 |
Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. | Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P | Science (New York, N.Y.) | 29599213 | Science | 2018 Mar 30 | https://www.ncbi.nlm.nih.gov/pubmed/29599213 |
Cell biology: Double agents for mitochondrial division. | McBride HM, Frost A | Nature | 27880759 | Nature | 2016 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/27880759 |
A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP. | Hwang J, Ribbens D, Raychaudhuri S, Cairns L, Gu H, Frost A, Urban S, Espenshade PJ | The EMBO journal | 27655872 | EMBO J | 2016 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/27655872 |
Structural inhibition of dynamin-mediated membrane fission by endophilin. | Hohendahl A, Talledge N, Galli V, Shen PS, Humbert F, De Camilli P, Frost A, Roux A | eLife | 28933693 | Elife | 2017 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/28933693 |
Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. | Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A | Science (New York, N.Y.) | 25554787 | Science | 2015 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/25554787 |
Functional role of PGAM5 multimeric assemblies and their polymerization into filaments. | Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N | Nature communications | 30705304 | Nat Commun | 2019 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/30705304 |
Structures, Functions, and Dynamics of ESCRT-III/Vps4 Membrane Remodeling and Fission Complexes. | McCullough J, Frost A, Sundquist WI | Annual review of cell and developmental biology | 30095293 | Annu Rev Cell Dev Biol | 2018 Oct 6 | https://www.ncbi.nlm.nih.gov/pubmed/30095293 |
A Tunable Microfluidic Device Enables Cargo Encapsulation by Cell- or Organelle-Sized Lipid Vesicles Comprising Asymmetric Lipid Bilayers. | Romanov V, McCullough J, Gale BK, Frost A | Advanced biosystems | 31428671 | Adv Biosyst | 2019 Jul | https://www.ncbi.nlm.nih.gov/pubmed/31428671 |
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. | Miller-Vedam LE, Bräuning B, Popova KD, Schirle Oakdale NT, Bonnar JL, Prabu JR, Boydston EA, Sevillano N, Shurtleff MJ, Stroud RM, Craik CS, Schulman BA, Frost A, Weissman JS | eLife | 33236988 | Elife | 2020 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/33236988 |
Photocatalytic LPOR forms helical lattices that shape membranes for chlorophyll synthesis. | Nguyen HC, Melo AA, Kruk J, Frost A, Gabruk M | Nature plants | 33875834 | Nat Plants | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33875834 |
Brominated lipid probes expose structural asymmetries in constricted membranes. | Moss FR 3rd, Lincoff J, Tucker M, Mohammed A, Grabe M, Frost A | Nature structural & molecular biology | 36624348 | Nat Struct Mol Biol | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36624348 |
Vms1p is a release factor for the ribosome-associated quality control complex. | Zurita Rendón O, Fredrickson EK, Howard CJ, Van Vranken J, Fogarty S, Tolley ND, Kalia R, Osuna BA, Shen PS, Hill CP, Frost A, Rutter J | Nature communications | 29875445 | Nat Commun | 2018 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/29875445 |
Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex. | Heider MR, Gu M, Duffy CM, Mirza AM, Marcotte LL, Walls AC, Farrall N, Hakhverdyan Z, Field MC, Rout MP, Frost A, Munson M | Nature structural & molecular biology | 26656853 | Nat Struct Mol Biol | 2016 Jan | https://www.ncbi.nlm.nih.gov/pubmed/26656853 |
Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission. | Koirala S, Guo Q, Kalia R, Bui HT, Eckert DM, Frost A, Shaw JM | Proceedings of the National Academy of Sciences of the United States of America | 23530241 | Proc Natl Acad Sci U S A | 2013 Apr 9 | https://www.ncbi.nlm.nih.gov/pubmed/23530241 |
eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. | Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A | Science (New York, N.Y.) | 31048491 | Science | 2019 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/31048491 |
Structural basis of mitochondrial receptor binding and constriction by DRP1. | Kalia R, Wang RY, Yusuf A, Thomas PV, Agard DA, Shaw JM, Frost A | Nature | 29899447 | Nature | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29899447 |
Membrane fission by dynamin: what we know and what we need to know. | Antonny B, Burd C, De Camilli P, Chen E, Daumke O, Faelber K, Ford M, Frolov VA, Frost A, Hinshaw JE, Kirchhausen T, Kozlov MM, Lenz M, Low HH, McMahon H, Merrifield C, Pollard TD, Robinson PJ, Roux A, Schmid S | The EMBO journal | 27670760 | EMBO J | 2016 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/27670760 |
The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. | Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH, Weissman JS | eLife | 29809151 | Elife | 2018 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/29809151 |
FDM 3D Printing of High-Pressure, Heat-Resistant, Transparent Microfluidic Devices. | Romanov V, Samuel R, Chaharlang M, Jafek AR, Frost A, Gale BK | Analytical chemistry | 30071717 | Anal Chem | 2018 Sep 4 | https://www.ncbi.nlm.nih.gov/pubmed/30071717 |
Exocyst structural changes associated with activation of tethering downstream of Rho/Cdc42 GTPases. | Rossi G, Lepore D, Kenner L, Czuchra AB, Plooster M, Frost A, Munson M, Brennwald P | The Journal of cell biology | 31904797 | J Cell Biol | 2020 Feb 3 | https://www.ncbi.nlm.nih.gov/pubmed/31904797 |
LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. | von Appen A, LaJoie D, Johnson IE, Trnka MJ, Pick SM, Burlingame AL, Ullman KS, Frost A | Nature | 32494070 | Nature | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32494070 |
CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. | Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, Weinberg DE, Weissman JS | Science (New York, N.Y.) | 28751611 | Science | 2017 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/28751611 |
Structural basis of TRPV1 modulation by endogenous bioactive lipids. | Arnold WR, Mancino A, Moss FR 3rd, Frost A, Julius D, Cheng Y | Nature structural & molecular biology | 38698206 | Nat Struct Mol Biol | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/38698206 |
A type VI secretion-related pathway in Bacteroidetes mediates interbacterial antagonism. | Russell AB, Wexler AG, Harding BN, Whitney JC, Bohn AJ, Goo YA, Tran BQ, Barry NA, Zheng H, Peterson SB, Chou S, Gonen T, Goodlett DR, Goodman AL, Mougous JD | Cell host & microbe | 25070807 | Cell Host Microbe | 2014 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/25070807 |
Mapping human microbiome drug metabolism by gut bacteria and their genes. | Zimmermann M, Zimmermann-Kogadeeva M, Wegmann R, Goodman AL | Nature | 31158845 | Nature | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31158845 |
Acetate mediates a microbiome-brain-β-cell axis to promote metabolic syndrome. | Perry RJ, Peng L, Barry NA, Cline GW, Zhang D, Cardone RL, Petersen KF, Kibbey RG, Goodman AL, Shulman GI | Nature | 27279214 | Nature | 2016 Jun 9 | https://www.ncbi.nlm.nih.gov/pubmed/27279214 |
Experimental approaches for defining functional roles of microbes in the human gut. | Dantas G, Sommer MO, Degnan PH, Goodman AL | Annual review of microbiology | 24024637 | Annu Rev Microbiol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24024637 |
Insights from pharmacokinetic models of host-microbiome drug metabolism. | Zimmermann-Kogadeeva M, Zimmermann M, Goodman AL | Gut microbes | 31564204 | Gut Microbes | 2020 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/31564204 |
Gut microbiota. Antimicrobial peptide resistance mediates resilience of prominent gut commensals during inflammation. | Cullen TW, Schofield WB, Barry NA, Putnam EE, Rundell EA, Trent MS, Degnan PH, Booth CJ, Yu H, Goodman AL | Science (New York, N.Y.) | 25574022 | Science | 2015 Jan 9 | https://www.ncbi.nlm.nih.gov/pubmed/25574022 |
Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria. | Tan Y, Zanoni I, Cullen TW, Goodman AL, Kagan JC | Immunity | 26546281 | Immunity | 2015 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/26546281 |
The Stringent Response Determines the Ability of a Commensal Bacterium to Survive Starvation and to Persist in the Gut. | Schofield WB, Zimmermann-Kogadeeva M, Zimmermann M, Barry NA, Goodman AL | Cell host & microbe | 30008292 | Cell Host Microbe | 2018 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/30008292 |
Engineered Regulatory Systems Modulate Gene Expression of Human Commensals in the Gut. | Lim B, Zimmermann M, Barry NA, Goodman AL | Cell | 28431252 | Cell | 2017 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/28431252 |
An insider's perspective: Bacteroides as a window into the microbiome. | Wexler AG, Goodman AL | Nature microbiology | 28440278 | Nat Microbiol | 2017 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/28440278 |
Separating host and microbiome contributions to drug pharmacokinetics and toxicity. | Zimmermann M, Zimmermann-Kogadeeva M, Wegmann R, Goodman AL | Science (New York, N.Y.) | 30733391 | Science | 2019 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/30733391 |
Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. | Palm NW, de Zoete MR, Cullen TW, Barry NA, Stefanowski J, Hao L, Degnan PH, Hu J, Peter I, Zhang W, Ruggiero E, Cho JH, Goodman AL, Flavell RA | Cell | 25171403 | Cell | 2014 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/25171403 |
Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. | Stein BD, Calzolari D, Hellberg K, Hu YS, He L, Hung CM, Toyama EQ, Ross DS, Lillemeier BF, Cantley LC, Yates JR 3rd, Shaw RJ | Cell reports | 31801093 | Cell Rep | 2019 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/31801093 |
The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity. | Heimbucher T, Liu Z, Bossard C, McCloskey R, Carrano AC, Riedel CG, Tanasa B, Klammt C, Fonslow BR, Riera CE, Lillemeier BF, Kemphues K, Yates JR 3rd, O'Shea C, Hunter T, Dillin A | Cell metabolism | 26154057 | Cell Metab | 2015 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/26154057 |
A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli. | Katz ZB, Novotná L, Blount A, Lillemeier BF | Nature immunology | 27869819 | Nat Immunol | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27869819 |
Superresolution imaging reveals nanometer- and micrometer-scale spatial distributions of T-cell receptors in lymph nodes. | Hu YS, Cang H, Lillemeier BF | Proceedings of the National Academy of Sciences of the United States of America | 27303041 | Proc Natl Acad Sci U S A | 2016 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/27303041 |
T cell receptor dwell times control the kinase activity of Zap70. | Klammt C, Novotná L, Li DT, Wolf M, Blount A, Zhang K, Fitchett JR, Lillemeier BF | Nature immunology | 26237552 | Nat Immunol | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26237552 |
Ant genomics sheds light on the molecular regulation of social organization. | Libbrecht R, Oxley PR, Kronauer DJ, Keller L | Genome biology | 23895728 | Genome Biol | 2013 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/23895728 |
The genome of the clonal raider ant Cerapachys biroi. | Oxley PR, Ji L, Fetter-Pruneda I, McKenzie SK, Li C, Hu H, Zhang G, Kronauer DJ | Current biology : CB | 24508170 | Curr Biol | 2014 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/24508170 |
Transcriptomics and neuroanatomy of the clonal raider ant implicate an expanded clade of odorant receptors in chemical communication. | McKenzie SK, Fetter-Pruneda I, Ruta V, Kronauer DJ | Proceedings of the National Academy of Sciences of the United States of America | 27911792 | Proc Natl Acad Sci U S A | 2016 Dec 6 | https://www.ncbi.nlm.nih.gov/pubmed/27911792 |
orco Mutagenesis Causes Loss of Antennal Lobe Glomeruli and Impaired Social Behavior in Ants. | Trible W, Olivos-Cisneros L, McKenzie SK, Saragosti J, Chang NC, Matthews BJ, Oxley PR, Kronauer DJC | Cell | 28802042 | Cell | 2017 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/28802042 |
Social regulation of insulin signaling and the evolution of eusociality in ants. | Chandra V, Fetter-Pruneda I, Oxley PR, Ritger AL, McKenzie SK, Libbrecht R, Kronauer DJC | Science (New York, N.Y.) | 30049879 | Science | 2018 Jul 27 | https://www.ncbi.nlm.nih.gov/pubmed/30049879 |
Robust DNA Methylation in the Clonal Raider Ant Brain. | Libbrecht R, Oxley PR, Keller L, Kronauer DJ | Current biology : CB | 26804553 | Curr Biol | 2016 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/26804553 |
Comparative genomics and transcriptomics in ants provide new insights into the evolution and function of odorant binding and chemosensory proteins. | McKenzie SK, Oxley PR, Kronauer DJ | BMC genomics | 25159315 | BMC Genomics | 2014 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/25159315 |
Ant larvae regulate worker foraging behavior and ovarian activity in a dose-dependent manner. | Ulrich Y, Burns D, Libbrecht R, Kronauer DJ | Behavioral ecology and sociobiology | 27616809 | Behav Ecol Sociobiol | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27616809 |
Clonal raider ant brain transcriptomics identifies candidate molecular mechanisms for reproductive division of labor. | Libbrecht R, Oxley PR, Kronauer DJC | BMC biology | 30103762 | BMC Biol | 2018 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/30103762 |
Fitness benefits and emergent division of labour at the onset of group living. | Ulrich Y, Saragosti J, Tokita CK, Tarnita CE, Kronauer DJC | Nature | 30135576 | Nature | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30135576 |
The genomic architecture and molecular evolution of ant odorant receptors. | McKenzie SK, Kronauer DJC | Genome research | 30249741 | Genome Res | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30249741 |
Srs2 prevents Rad51 filament formation by repetitive motion on DNA. | Qiu Y, Antony E, Doganay S, Koh HR, Lohman TM, Myong S | Nature communications | 23939144 | Nat Commun | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23939144 |
Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing. | Koh HR, Xing L, Kleiman L, Myong S | Nucleic acids research | 24914047 | Nucleic Acids Res | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24914047 |
G-quadruplex conformation and dynamics are determined by loop length and sequence. | Tippana R, Xiao W, Myong S | Nucleic acids research | 24920827 | Nucleic Acids Res | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24920827 |
Single-molecule real-time detection of telomerase extension activity. | Hwang H, Opresko P, Myong S | Scientific reports | 25263700 | Sci Rep | 2014 Sep 29 | https://www.ncbi.nlm.nih.gov/pubmed/25263700 |
The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics. | Elbaum-Garfinkle S, Kim Y, Szczepaniak K, Chen CC, Eckmann CR, Myong S, Brangwynne CP | Proceedings of the National Academy of Sciences of the United States of America | 26015579 | Proc Natl Acad Sci U S A | 2015 Jun 9 | https://www.ncbi.nlm.nih.gov/pubmed/26015579 |
Visualizing repetitive diffusion activity of double-strand RNA binding proteins by single molecule fluorescence assays. | Koh HR, Wang X, Myong S | Methods (San Diego, Calif.) | 27012177 | Methods | 2016 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/27012177 |
RNA stem structure governs coupling of dicing and gene silencing in RNA interference. | Koh HR, Ghanbariniaki A, Myong S | Proceedings of the National Academy of Sciences of the United States of America | 29133395 | Proc Natl Acad Sci U S A | 2017 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/29133395 |
Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. | Chen MC, Tippana R, Demeshkina NA, Murat P, Balasubramanian S, Myong S, Ferré-D'Amaré AR | Nature | 29899445 | Nature | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29899445 |
RNA Remodeling Activity of DEAD Box Proteins Tuned by Protein Concentration, RNA Length, and ATP. | Kim Y, Myong S | Molecular cell | 27546789 | Mol Cell | 2016 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/27546789 |
Substrate recognition and specificity of double-stranded RNA binding proteins. | Vuković L, Koh HR, Myong S, Schulten K | Biochemistry | 24801449 | Biochemistry | 2014 Jun 3 | https://www.ncbi.nlm.nih.gov/pubmed/24801449 |
Single-Cell Imaging Approaches for Studying Small-RNA-Induced Gene Regulation. | Koh HR, Myong S | Biophysical journal | 29970232 | Biophys J | 2018 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/29970232 |
G-Quadruplex and Protein Binding by Single-Molecule FRET Microscopy. | Lee CY, McNerney C, Myong S | Methods in molecular biology (Clifton, N.J.) | 31444758 | Methods Mol Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31444758 |
Dynamic profiling of double-stranded RNA binding proteins. | Wang X, Vukovic L, Koh HR, Schulten K, Myong S | Nucleic acids research | 26184879 | Nucleic Acids Res | 2015 Sep 3 | https://www.ncbi.nlm.nih.gov/pubmed/26184879 |
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. | Bell RJ, Rube HT, Kreig A, Mancini A, Fouse SD, Nagarajan RP, Choi S, Hong C, He D, Pekmezci M, Wiencke JK, Wrensch MR, Chang SM, Walsh KM, Myong S, Song JS, Costello JF | Science (New York, N.Y.) | 25977370 | Science | 2015 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/25977370 |
Molecular mechanism of resolving trinucleotide repeat hairpin by helicases. | Qiu Y, Niu H, Vukovic L, Sung P, Myong S | Structure (London, England : 1993) | 26004439 | Structure | 2015 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/26004439 |
POT1-TPP1 regulates telomeric overhang structural dynamics. | Hwang H, Buncher N, Opresko PL, Myong S | Structure (London, England : 1993) | 22981946 | Structure | 2012 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/22981946 |
The Chd1 Chromatin Remodeler Shifts Nucleosomal DNA Bidirectionally as a Monomer. | Qiu Y, Levendosky RF, Chakravarthy S, Patel A, Bowman GD, Myong S | Molecular cell | 28943314 | Mol Cell | 2017 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/28943314 |
mRNA structure determines specificity of a polyQ-driven phase separation. | Langdon EM, Qiu Y, Ghanbari Niaki A, McLaughlin GA, Weidmann CA, Gerbich TM, Smith JA, Crutchley JM, Termini CM, Weeks KM, Myong S, Gladfelter AS | Science (New York, N.Y.) | 29650703 | Science | 2018 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/29650703 |
Quantitative analysis and prediction of G-quadruplex forming sequences in double-stranded DNA. | Kim M, Kreig A, Lee CY, Rube HT, Calvert J, Song JS, Myong S | Nucleic acids research | 27095201 | Nucleic Acids Res | 2016 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/27095201 |
Oxidative guanine base damage regulates human telomerase activity. | Fouquerel E, Lormand J, Bose A, Lee HT, Kim GS, Li J, Sobol RW, Freudenthal BD, Myong S, Opresko PL | Nature structural & molecular biology | 27820808 | Nat Struct Mol Biol | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27820808 |
RNA Scanning of a Molecular Machine with a Built-in Ruler. | Koh HR, Kidwell MA, Doudna J, Myong S | Journal of the American Chemical Society | 27958730 | J Am Chem Soc | 2017 Jan 11 | https://www.ncbi.nlm.nih.gov/pubmed/27958730 |
Single-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicases. | Tippana R, Hwang H, Opresko PL, Bohr VA, Myong S | Proceedings of the National Academy of Sciences of the United States of America | 27407146 | Proc Natl Acad Sci U S A | 2016 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/27407146 |
ATP-independent diffusion of double-stranded RNA binding proteins. | Koh HR, Kidwell MA, Ragunathan K, Doudna JA, Myong S | Proceedings of the National Academy of Sciences of the United States of America | 23251028 | Proc Natl Acad Sci U S A | 2013 Jan 2 | https://www.ncbi.nlm.nih.gov/pubmed/23251028 |
Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins. | Hwang H, Kreig A, Calvert J, Lormand J, Kwon Y, Daley JM, Sung P, Opresko PL, Myong S | Structure (London, England : 1993) | 24836024 | Structure | 2014 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/24836024 |
G-quadruplex formation in double strand DNA probed by NMM and CV fluorescence. | Kreig A, Calvert J, Sanoica J, Cullum E, Tipanna R, Myong S | Nucleic acids research | 26202971 | Nucleic Acids Res | 2015 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/26202971 |
An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. | Zhao Z, Lee RT, Pusapati GV, Iyu A, Rohatgi R, Ingham PW | EMBO reports | 27113758 | EMBO Rep | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27113758 |
Lipid droplets can promote drug accumulation and activation. | Dubey R, Stivala CE, Nguyen HQ, Goo YH, Paul A, Carette JE, Trost BM, Rohatgi R | Nature chemical biology | 31932720 | Nat Chem Biol | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31932720 |
Phase separation-deficient TDP43 remains functional in splicing. | Schmidt HB, Barreau A, Rohatgi R | Nature communications | 31653829 | Nat Commun | 2019 Oct 25 | https://www.ncbi.nlm.nih.gov/pubmed/31653829 |
EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia. | Pusapati GV, Hughes CE, Dorn KV, Zhang D, Sugianto P, Aravind L, Rohatgi R | Developmental cell | 24582806 | Dev Cell | 2014 Mar 10 | https://www.ncbi.nlm.nih.gov/pubmed/24582806 |
G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog. | Pusapati GV, Kong JH, Patel BB, Gouti M, Sagner A, Sircar R, Luchetti G, Ingham PW, Briscoe J, Rohatgi R | Science signaling | 29438014 | Sci Signal | 2018 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/29438014 |
Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1. | Dubey R, Lebensohn AM, Bahrami-Nejad Z, Marceau C, Champion M, Gevaert O, Sikic BI, Carette JE, Rohatgi R | Cancer research | 27503929 | Cancer Res | 2016 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/27503929 |
Measuring Expression Levels of Endogenous Gli Genes by Immunoblotting and Real-Time PCR. | Niewiadomski P, Rohatgi R | Methods in molecular biology (Clifton, N.J.) | 26179041 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26179041 |
Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry. | Ahrends R, Niewiadomski P, Teruel MN, Rohatgi R | Methods in molecular biology (Clifton, N.J.) | 26179043 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26179043 |
In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes. | Schmidt HB, Rohatgi R | Cell reports | 27452472 | Cell Rep | 2016 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/27452472 |
R-spondins can potentiate WNT signaling without LGRs. | Lebensohn AM, Rohatgi R | eLife | 29405118 | Elife | 2018 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/29405118 |
CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog. | Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R | Developmental cell | 29290584 | Dev Cell | 2018 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/29290584 |
Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. | Kong JH, Yang L, Dessaud E, Chuang K, Moore DM, Rohatgi R, Briscoe J, Novitch BG | Developmental cell | 25936505 | Dev Cell | 2015 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/25936505 |
G-protein-coupled receptors, Hedgehog signaling and primary cilia. | Mukhopadhyay S, Rohatgi R | Seminars in cell & developmental biology | 24845016 | Semin Cell Dev Biol | 2014 Sep | https://www.ncbi.nlm.nih.gov/pubmed/24845016 |
TDP-43 α-helical structure tunes liquid-liquid phase separation and function. | Conicella AE, Dignon GL, Zerze GH, Schmidt HB, D'Ordine AM, Kim YC, Rohatgi R, Ayala YM, Mittal J, Fawzi NL | Proceedings of the National Academy of Sciences of the United States of America | 32132204 | Proc Natl Acad Sci U S A | 2020 Mar 17 | https://www.ncbi.nlm.nih.gov/pubmed/32132204 |
Multiple ligand binding sites regulate the Hedgehog signal transducer Smoothened in vertebrates. | Byrne EF, Luchetti G, Rohatgi R, Siebold C | Current opinion in cell biology | 29268141 | Curr Opin Cell Biol | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29268141 |
CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog. | Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R | Developmental cell | 29401421 | Dev Cell | 2018 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/29401421 |
Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. | Lebensohn AM, Dubey R, Neitzel LR, Tacchelly-Benites O, Yang E, Marceau CD, Davis EM, Patel BB, Bahrami-Nejad Z, Travaglini KJ, Ahmed Y, Lee E, Carette JE, Rohatgi R | eLife | 27996937 | Elife | 2016 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/27996937 |
Cholesterol accessibility at the ciliary membrane controls hedgehog signaling. | Kinnebrew M, Iverson EJ, Patel BB, Pusapati GV, Kong JH, Johnson KA, Luchetti G, Eckert KM, McDonald JG, Covey DF, Siebold C, Radhakrishnan A, Rohatgi R | eLife | 31657721 | Elife | 2019 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/31657721 |
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. | Phua SC, Chiba S, Suzuki M, Su E, Roberson EC, Pusapati GV, Schurmans S, Setou M, Rohatgi R, Reiter JF, Ikegami K, Inoue T | Cell | 28086093 | Cell | 2017 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/28086093 |
A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing. | Wang A, Conicella AE, Schmidt HB, Martin EW, Rhoads SN, Reeb AN, Nourse A, Ramirez Montero D, Ryan VH, Rohatgi R, Shewmaker F, Naik MT, Mittag T, Ayala YM, Fawzi NL | The EMBO journal | 29438978 | EMBO J | 2018 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/29438978 |
Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens. | Patel BB, Lebensohn AM, Pusapati GV, Carette JE, Salzman J, Rohatgi R | PloS one | 30695034 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30695034 |
Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling. | Hong SR, Wang CL, Huang YS, Chang YC, Chang YC, Pusapati GV, Lin CY, Hsu N, Cheng HC, Chiang YC, Huang WE, Shaner NC, Rohatgi R, Inoue T, Lin YC | Nature communications | 29712905 | Nat Commun | 2018 Apr 30 | https://www.ncbi.nlm.nih.gov/pubmed/29712905 |
Rapid Screening of Gli2/3 Mutants Using the Flp-In System. | Niewiadomski P, Rohatgi R | Methods in molecular biology (Clifton, N.J.) | 26179044 | Methods Mol Biol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26179044 |
Photoactivatable protein labeling by singlet oxygen mediated reactions. | To TL, Medzihradszky KF, Burlingame AL, DeGrado WF, Jo H, Shu X | Bioorganic & medicinal chemistry letters | 27220724 | Bioorg Med Chem Lett | 2016 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/27220724 |
Precision Optogenetic Tool for Selective Single- and Multiple-Cell Ablation in a Live Animal Model System. | Makhijani K, To TL, Ruiz-González R, Lafaye C, Royant A, Shu X | Cell chemical biology | 28065655 | Cell Chem Biol | 2017 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/28065655 |
Singlet oxygen triplet energy transfer-based imaging technology for mapping protein-protein proximity in intact cells. | To TL, Fadul MJ, Shu X | Nature communications | 24905026 | Nat Commun | 2014 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/24905026 |
Dynamic Imaging of Small Molecule Induced Protein-Protein Interactions in Living Cells with a Fluorophore Phase Transition Based Approach. | Chung CI, Zhang Q, Shu X | Analytical chemistry | 30431263 | Anal Chem | 2018 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/30431263 |
Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. | Zhang Q, Huang H, Zhang L, Wu R, Chung CI, Zhang SQ, Torra J, Schepis A, Coughlin SR, Kornberg TB, Shu X | Molecular cell | 29307513 | Mol Cell | 2018 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/29307513 |
A rapid fluorogenic GPCR-β-arrestin interaction assay. | Zhang Q, Zheng YW, Coughlin SR, Shu X | Protein science : a publication of the Protein Society | 29411438 | Protein Sci | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29411438 |
Structure-guided design of a reversible fluorogenic reporter of protein-protein interactions. | To TL, Zhang Q, Shu X | Protein science : a publication of the Protein Society | 26690964 | Protein Sci | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26690964 |
Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network. | Culyba MJ, Kubiak JM, Mo CY, Goulian M, Kohli RM | PLoS genetics | 29856734 | PLoS Genet | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29856734 |
Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response. | Selwood T, Larsen BJ, Mo CY, Culyba MJ, Hostetler ZM, Kohli RM, Reitz AB, Baugh SDP | Frontiers in microbiology | 30619111 | Front Microbiol | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30619111 |
Systematically Altering Bacterial SOS Activity under Stress Reveals Therapeutic Strategies for Potentiating Antibiotics. | Mo CY, Manning SA, Roggiani M, Culyba MJ, Samuels AN, Sniegowski PD, Goulian M, Kohli RM | mSphere | 27536734 | mSphere | 2016 Jul-Aug | https://www.ncbi.nlm.nih.gov/pubmed/27536734 |
A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage. | Kubiak JM, Culyba MJ, Liu MY, Mo CY, Goulian M, Kohli RM | ACS synthetic biology | 28826208 | ACS Synth Biol | 2017 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/28826208 |
Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection. | Sungwienwong I, Hostetler ZM, Blizzard RJ, Porter JJ, Driggers CM, Mbengi LZ, Villegas JA, Speight LC, Saven JG, Perona JJ, Kohli RM, Mehl RA, Petersson EJ | Organic & biomolecular chemistry | 28397914 | Org Biomol Chem | 2017 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/28397914 |
Specificity determinants for autoproteolysis of LexA, a key regulator of bacterial SOS mutagenesis. | Mo CY, Birdwell LD, Kohli RM | Biochemistry | 24779472 | Biochemistry | 2014 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/24779472 |
Targets for Combating the Evolution of Acquired Antibiotic Resistance. | Culyba MJ, Mo CY, Kohli RM | Biochemistry | 26016604 | Biochemistry | 2015 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/26016604 |
DNA Methyltransferases Demonstrate Reduced Activity against Arabinosylcytosine: Implications for Epigenetic Instability in Acute Myeloid Leukemia. | Nabel CS, DeNizio JE, Carroll M, Kohli RM | Biochemistry | 28394581 | Biochemistry | 2017 Apr 25 | https://www.ncbi.nlm.nih.gov/pubmed/28394581 |
Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership. | Mo CY, Culyba MJ, Selwood T, Kubiak JM, Hostetler ZM, Jurewicz AJ, Keller PM, Pope AJ, Quinn A, Schneck J, Widdowson KL, Kohli RM | ACS infectious diseases | 29275629 | ACS Infect Dis | 2018 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/29275629 |
Simple and versatile imaging of genomic loci in live mammalian cells and early pre-implantation embryos using CAS-LiveFISH. | Geng Y, Pertsinidis A | Scientific reports | 34108610 | Sci Rep | 2021 Jun 9 | https://www.ncbi.nlm.nih.gov/pubmed/34108610 |
Single-Molecule Real-Time 3D Imaging of the Transcription Cycle by Modulation Interferometry. | Wang G, Hauver J, Thomas Z, Darst SA, Pertsinidis A | Cell | 27984731 | Cell | 2016 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/27984731 |
Volumetric interferometric lattice light-sheet imaging. | Cao B, Coelho S, Li J, Wang G, Pertsinidis A | Nature biotechnology | 34635835 | Nat Biotechnol | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34635835 |
Topoisomerase III Acts at the Replication Fork To Remove Precatenanes. | Lee CM, Wang G, Pertsinidis A, Marians KJ | Journal of bacteriology | 30617245 | J Bacteriol | 2019 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/30617245 |
Single-gene imaging links genome topology, promoter-enhancer communication and transcription control. | Li J, Hsu A, Hua Y, Wang G, Cheng L, Ochiai H, Yamamoto T, Pertsinidis A | Nature structural & molecular biology | 32958948 | Nat Struct Mol Biol | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32958948 |
A Single-Molecule Surface-Based Platform to Detect the Assembly and Function of the Human RNA Polymerase II Transcription Machinery. | Park SR, Hauver J, Zhang Y, Revyakin A, Coleman RA, Tjian R, Chu S, Pertsinidis A | Structure (London, England : 1993) | 32763141 | Structure | 2020 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/32763141 |
Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells. | Li J, Dong A, Saydaminova K, Chang H, Wang G, Ochiai H, Yamamoto T, Pertsinidis A | Cell | 31155237 | Cell | 2019 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/31155237 |
A Membrane-Embedded Amino Acid Couples the SpoIIQ Channel Protein to Anti-Sigma Factor Transcriptional Repression during Bacillus subtilis Sporulation. | Flanagan KA, Comber JD, Mearls E, Fenton C, Wang Erickson AF, Camp AH | Journal of bacteriology | 26929302 | J Bacteriol | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/26929302 |
Structural and biochemical characterization of SpoIIIAF, a component of a sporulation-essential channel in Bacillus subtilis. | Zeytuni N, Flanagan KA, Worrall LJ, Massoni SC, Camp AH, Strynadka NCJ | Journal of structural biology | 29886194 | J Struct Biol | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29886194 |
Near-atomic resolution cryoelectron microscopy structure of the 30-fold homooligomeric SpoIIIAG channel essential to spore formation in Bacillus subtilis. | Zeytuni N, Hong C, Flanagan KA, Worrall LJ, Theiltges KA, Vuckovic M, Huang RK, Massoni SC, Camp AH, Yu Z, Strynadka NC | Proceedings of the National Academy of Sciences of the United States of America | 28784753 | Proc Natl Acad Sci U S A | 2017 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/28784753 |
Structural Analysis of Bacillus subtilis Sigma Factors. | Collins KM, Evans NJ, Torpey JH, Harris JM, Haynes BA, Camp AH, Isaacson RL | Microorganisms | 37110501 | Microorganisms | 2023 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/37110501 |
MdfA is a novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore. | Massoni SC, Evans NJ, Hantke I, Fenton C, Torpey JH, Collins KM, Krysztofinska EM, Muench JH, Thapaliya A, Martínez-Lumbreras S, Hart Ferrell S, Slater C, Wang X, Fekade R, Obwar S, Yin S, Vazquez A, Prior CB, Turgay K, Isaacson RL, Camp AH | Genes & development | 40086879 | Genes Dev | 2025 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/40086879 |
Structural and Functional Insights into Bacillus subtilis Sigma Factor Inhibitor, CsfB. | Martínez-Lumbreras S, Alfano C, Evans NJ, Collins KM, Flanagan KA, Atkinson RA, Krysztofinska EM, Vydyanath A, Jackter J, Fixon-Owoo S, Camp AH, Isaacson RL | Structure (London, England : 1993) | 29526435 | Structure | 2018 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/29526435 |
Structural characterization of SpoIIIAB sporulation-essential protein in Bacillus subtilis. | Zeytuni N, Flanagan KA, Worrall LJ, Massoni SC, Camp AH, Strynadka NCJ | Journal of structural biology | 29288127 | J Struct Biol | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29288127 |
Developmentally regulated proteolysis by MdfA and ClpCP mediates metabolic differentiation during Bacillus subtilis sporulation. | Riley EP, Lyda JA, Reyes-Matte O, Sugie J, Kasu IR, Enustun E, Armbruster EG, Ravishankar S, Isaacson RL, Camp AH, Lopez-Garrido J, Pogliano K | Genes & development | 40086876 | Genes Dev | 2025 Mar 14 | https://www.ncbi.nlm.nih.gov/pubmed/40086876 |
Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics. | Taylor N, Elbaum-Garfinkle S, Vaidya N, Zhang H, Stone HA, Brangwynne CP | Soft matter | 27791212 | Soft Matter | 2016 Nov 16 | https://www.ncbi.nlm.nih.gov/pubmed/27791212 |
Inverse size scaling of the nucleolus by a concentration-dependent phase transition. | Weber SC, Brangwynne CP | Current biology : CB | 25702583 | Curr Biol | 2015 Mar 2 | https://www.ncbi.nlm.nih.gov/pubmed/25702583 |
Liquid phase condensation in cell physiology and disease. | Shin Y, Brangwynne CP | Science (New York, N.Y.) | 28935776 | Science | 2017 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/28935776 |
Farming and public goods production in Caenorhabditis elegans populations. | Thutupalli S, Uppaluri S, Constable GW, Levin SA, Stone HA, Tarnita CE, Brangwynne CP | Proceedings of the National Academy of Sciences of the United States of America | 28183799 | Proc Natl Acad Sci U S A | 2017 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/28183799 |
Remodeling nuclear architecture allows efficient transport of herpesvirus capsids by diffusion. | Bosse JB, Hogue IB, Feric M, Thiberge SY, Sodeik B, Brangwynne CP, Enquist LW | Proceedings of the National Academy of Sciences of the United States of America | 26438852 | Proc Natl Acad Sci U S A | 2015 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/26438852 |
Nuclear bodies: the emerging biophysics of nucleoplasmic phases. | Zhu L, Brangwynne CP | Current opinion in cell biology | 25942753 | Curr Opin Cell Biol | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25942753 |
Soft viscoelastic properties of nuclear actin age oocytes due to gravitational creep. | Feric M, Broedersz CP, Brangwynne CP | Scientific reports | 26577186 | Sci Rep | 2015 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/26577186 |
RNA transcription modulates phase transition-driven nuclear body assembly. | Berry J, Weber SC, Vaidya N, Haataja M, Brangwynne CP | Proceedings of the National Academy of Sciences of the United States of America | 26351690 | Proc Natl Acad Sci U S A | 2015 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/26351690 |
Hierarchical Size Scaling during Multicellular Growth and Development. | Uppaluri S, Weber SC, Brangwynne CP | Cell reports | 27705784 | Cell Rep | 2016 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/27705784 |
Getting RNA and protein in phase. | Weber SC, Brangwynne CP | Cell | 22682242 | Cell | 2012 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/22682242 |
A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells. | Feric M, Brangwynne CP | Nature cell biology | 23995731 | Nat Cell Biol | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23995731 |
Worms under Pressure: Bulk Mechanical Properties of C. elegans Are Independent of the Cuticle. | Gilpin W, Uppaluri S, Brangwynne CP | Biophysical journal | 25902429 | Biophys J | 2015 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/25902429 |
RNA Controls PolyQ Protein Phase Transitions. | Zhang H, Elbaum-Garfinkle S, Langdon EM, Taylor N, Occhipinti P, Bridges AA, Brangwynne CP, Gladfelter AS | Molecular cell | 26474065 | Mol Cell | 2015 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/26474065 |
A size threshold governs Caenorhabditis elegans developmental progression. | Uppaluri S, Brangwynne CP | Proceedings. Biological sciences | 26290076 | Proc Biol Sci | 2015 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/26290076 |
Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets. | Shin Y, Berry J, Pannucci N, Haataja MP, Toettcher JE, Brangwynne CP | Cell | 28041848 | Cell | 2017 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/28041848 |
The micro and macro of RNA function. | Brangwynne CP, Johnson TL | Molecular biology of the cell | 23486403 | Mol Biol Cell | 2013 Mar | https://www.ncbi.nlm.nih.gov/pubmed/23486403 |
Phase transitions and size scaling of membrane-less organelles. | Brangwynne CP | The Journal of cell biology | 24368804 | J Cell Biol | 2013 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/24368804 |
Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles. | Wei MT, Elbaum-Garfinkle S, Holehouse AS, Chen CC, Feric M, Arnold CB, Priestley RD, Pappu RV, Brangwynne CP | Nature chemistry | 29064502 | Nat Chem | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/29064502 |
Coexisting Liquid Phases Underlie Nucleolar Subcompartments. | Feric M, Vaidya N, Harmon TS, Mitrea DM, Zhu L, Richardson TM, Kriwacki RW, Pappu RV, Brangwynne CP | Cell | 27212236 | Cell | 2016 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/27212236 |
Interfacing Biocompatible Reactions with Engineered Escherichia coli. | Wallace S, Balskus EP | Methods in molecular biology (Clifton, N.J.) | 28470621 | Methods Mol Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28470621 |
Using non-enzymatic chemistry to influence microbial metabolism. | Wallace S, Schultz EE, Balskus EP | Current opinion in chemical biology | 25579453 | Curr Opin Chem Biol | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25579453 |
Rescuing auxotrophic microorganisms with nonenzymatic chemistry. | Lee Y, Umeano A, Balskus EP | Angewandte Chemie (International ed. in English) | 24115592 | Angew Chem Int Ed Engl | 2013 Nov 4 | https://www.ncbi.nlm.nih.gov/pubmed/24115592 |
A biocompatible alkene hydrogenation merges organic synthesis with microbial metabolism. | Sirasani G, Tong L, Balskus EP | Angewandte Chemie (International ed. in English) | 24916924 | Angew Chem Int Ed Engl | 2014 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/24916924 |
Interfacing microbial styrene production with a biocompatible cyclopropanation reaction. | Wallace S, Balskus EP | Angewandte Chemie (International ed. in English) | 25925138 | Angew Chem Int Ed Engl | 2015 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/25925138 |
Lomaiviticin biosynthesis employs a new strategy for starter unit generation. | Waldman AJ, Balskus EP | Organic letters | 24383813 | Org Lett | 2014 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/24383813 |
Opportunities for merging chemical and biological synthesis. | Wallace S, Balskus EP | Current opinion in biotechnology | 24747284 | Curr Opin Biotechnol | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/24747284 |
The l-Alanosine Gene Cluster Encodes a Pathway for Diazeniumdiolate Biosynthesis. | Ng TL, McCallum ME, Zheng CR, Wang JX, Wu KJY, Balskus EP | Chembiochem : a European journal of chemical biology | 31643127 | Chembiochem | 2020 Apr 17 | https://www.ncbi.nlm.nih.gov/pubmed/31643127 |
Discovery of a Diazo-Forming Enzyme in Cremeomycin Biosynthesis. | Waldman AJ, Balskus EP | The Journal of organic chemistry | 29771512 | J Org Chem | 2018 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/29771512 |
Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis. | Waldman AJ, Ng TL, Wang P, Balskus EP | Chemical reviews | 28375000 | Chem Rev | 2017 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/28375000 |
Discovery of the Azaserine Biosynthetic Pathway Uncovers a Biological Route for α-Diazoester Production. | Van Cura D, Ng TL, Huang J, Hager H, Hartwig JF, Keasling JD, Balskus EP | Angewandte Chemie (International ed. in English) | 37151182 | Angew Chem Int Ed Engl | 2023 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/37151182 |
Discovery of the lomaiviticin biosynthetic gene cluster in Salinispora pacifica. | Janso JE, Haltli BA, Eustáquio AS, Kulowski K, Waldman AJ, Zha L, Nakamura H, Bernan VS, He H, Carter GT, Koehn FE, Balskus EP | Tetrahedron | 25045187 | Tetrahedron | 2014 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/25045187 |
Production of Stealthin C Involves an S-N-Type Smiles Rearrangement. | Wang P, Hong GJ, Wilson MR, Balskus EP | Journal of the American Chemical Society | 28191843 | J Am Chem Soc | 2017 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/28191843 |
An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin. | Ng TL, Rohac R, Mitchell AJ, Boal AK, Balskus EP | Nature | 30728519 | Nature | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30728519 |
Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin. | Wang KA, Ng TL, Wang P, Huang Z, Balskus EP, van der Donk WA | Nature communications | 30206228 | Nat Commun | 2018 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/30206228 |
A Peroxodiiron(III/III) Intermediate Mediating Both N-Hydroxylation Steps in Biosynthesis of the N-Nitrosourea Pharmacophore of Streptozotocin by the Multi-domain Metalloenzyme SznF. | McBride MJ, Sil D, Ng TL, Crooke AM, Kenney GE, Tysoe CR, Zhang B, Balskus EP, Boal AK, Krebs C, Bollinger JM Jr | Journal of the American Chemical Society | 32511919 | J Am Chem Soc | 2020 Jul 8 | https://www.ncbi.nlm.nih.gov/pubmed/32511919 |
The Cremeomycin Biosynthetic Gene Cluster Encodes a Pathway for Diazo Formation. | Waldman AJ, Pechersky Y, Wang P, Wang JX, Balskus EP | Chembiochem : a European journal of chemical biology | 26278892 | Chembiochem | 2015 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/26278892 |
Designer Micelles Accelerate Flux Through Engineered Metabolism in E. coli and Support Biocompatible Chemistry. | Wallace S, Balskus EP | Angewandte Chemie (International ed. in English) | 27061024 | Angew Chem Int Ed Engl | 2016 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/27061024 |
Understanding collective behavior through neurobiology. | Yu JH, Napoli JL, Lovett-Barron M | Current opinion in neurobiology | 38852986 | Curr Opin Neurobiol | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38852986 |
Development of neural circuits for social motion perception in schooling fish. | Zada D, Schulze L, Yu JH, Tarabishi P, Napoli JL, Lovett-Barron M | bioRxiv : the preprint server for biology | 37961196 | bioRxiv | 2023 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/37961196 |
Development of neural circuits for social motion perception in schooling fish. | Zada D, Schulze L, Yu JH, Tarabishi P, Napoli JL, Milan J, Lovett-Barron M | Current biology : CB | 39025069 | Curr Biol | 2024 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/39025069 |
A concentration of visual cortex-like neurons in prefrontal cortex. | Rose O, Ponce CR | Nature communications | 39143147 | Nat Commun | 2024 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/39143147 |
Connectomic reconstruction predicts the functional organization of visual inputs to the navigation center of the Drosophila brain. | Garner D, Kind E, Nern A, Houghton L, Zhao A, Sancer G, Rubin GM, Wernet MF, Kim SS | bioRxiv : the preprint server for biology | 38076786 | bioRxiv | 2023 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/38076786 |
Connectomic reconstruction predicts visual features used for navigation. | Garner D, Kind E, Lai JYH, Nern A, Zhao A, Houghton L, Sancer G, Wolff T, Rubin GM, Wernet MF, Kim SS | Nature | 39358517 | Nature | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39358517 |
Neuronal "parts list" and wiring diagram for a visual system. | Matsliah A, Yu SC, Kruk K, Bland D, Burke A, Gager J, Hebditch J, Silverman B, Willie K, Willie RW, Sorek M, Sterling AR, Kind E, Garner D, Sancer G, Wernet MF, Kim SS, Murthy M, Seung HS, FlyWire Consortium | bioRxiv : the preprint server for biology | 37873160 | bioRxiv | 2024 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/37873160 |
Plasticity between visual input pathways and the head direction system. | Kim SS | Current opinion in neurobiology | 34619578 | Curr Opin Neurobiol | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34619578 |
Neuronal parts list and wiring diagram for a visual system. | Matsliah A, Yu SC, Kruk K, Bland D, Burke AT, Gager J, Hebditch J, Silverman B, Willie KP, Willie R, Sorek M, Sterling AR, Kind E, Garner D, Sancer G, Wernet MF, Kim SS, Murthy M, Seung HS, FlyWire Consortium | Nature | 39358525 | Nature | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39358525 |
LKB1 coordinates neurite remodeling to drive synapse layer emergence in the outer retina. | Burger CA, Alevy J, Casasent AK, Jiang D, Albrecht NE, Liang JH, Hirano AA, Brecha NC, Samuel MA | eLife | 32378514 | Elife | 2020 May 7 | https://www.ncbi.nlm.nih.gov/pubmed/32378514 |
LKB1 and AMPK instruct cone nuclear position to modify visual function. | Burger CA, Albrecht NE, Jiang D, Liang JH, Poché RA, Samuel MA | Cell reports | 33535040 | Cell Rep | 2021 Feb 2 | https://www.ncbi.nlm.nih.gov/pubmed/33535040 |
Neuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina. | Jiang D, Burger CA, Akhanov V, Liang JH, Mackin RD, Albrecht NE, Andrade P, Schafer DP, Samuel MA | Immunity | 36379210 | Immunity | 2022 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/36379210 |
Progressive myoclonic epilepsy-associated gene Kctd7 regulates retinal neurovascular patterning and function. | Alevy J, Burger CA, Albrecht NE, Jiang D, Samuel MA | Neurochemistry international | 31175897 | Neurochem Int | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31175897 |
Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae. | Jiang D, Burger CA, Casasent AK, Albrecht NE, Li F, Samuel MA | The Journal of comparative neurology | 31609468 | J Comp Neurol | 2020 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/31609468 |
Becoming a Principal Investigator: Designing and Navigating Your Academic Adventure. | Greer PL, Samuel MA | Neuron | 31557459 | Neuron | 2019 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/31557459 |
Development and maintenance of vision's first synapse. | Burger CA, Jiang D, Mackin RD, Samuel MA | Developmental biology | 33848537 | Dev Biol | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/33848537 |
Rapid and Integrative Discovery of Retina Regulatory Molecules. | Albrecht NE, Alevy J, Jiang D, Burger CA, Liu BI, Li F, Wang J, Kim SY, Hsu CW, Kalaga S, Udensi U, Asomugha C, Bohat R, Gaspero A, Justice MJ, Westenskow PD, Yamamoto S, Seavitt JR, Beaudet AL, Dickinson ME, Samuel MA | Cell reports | 30157441 | Cell Rep | 2018 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/30157441 |
Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects. | Liang JH, Alevy J, Akhanov V, Seo R, Massey CA, Jiang D, Zhou J, Sillitoe RV, Noebels JL, Samuel MA | Disease models & mechanisms | 35972048 | Dis Model Mech | 2022 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/35972048 |
Single-cell RNA-Seq of Defined Subsets of Retinal Ganglion Cells. | Laboissonniere LA, Sonoda T, Lee SK, Trimarchi JM, Schmidt TM | Journal of visualized experiments : JoVE | 28570514 | J Vis Exp | 2017 May 22 | https://www.ncbi.nlm.nih.gov/pubmed/28570514 |
Flp-recombinase mouse line for genetic manipulation of ipRGCs. | Contreras E, Liang C, Mahoney HL, Javier JL, Luce ML, Labastida Medina K, Bozza T, Schmidt TM | bioRxiv : the preprint server for biology | 38766000 | bioRxiv | 2024 May 8 | https://www.ncbi.nlm.nih.gov/pubmed/38766000 |
The Retinal Basis of Light Aversion in Neonatal Mice. | Caval-Holme FS, Aranda ML, Chen AQ, Tiriac A, Zhang Y, Smith B, Birnbaumer L, Schmidt TM, Feller MB | The Journal of neuroscience : the official journal of the Society for Neuroscience | 35396331 | J Neurosci | 2022 May 18 | https://www.ncbi.nlm.nih.gov/pubmed/35396331 |
Divergent projection patterns of M1 ipRGC subtypes. | Li JY, Schmidt TM | The Journal of comparative neurology | 29888785 | J Comp Neurol | 2018 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/29888785 |
Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits. | Sonoda T, Lee SK, Birnbaumer L, Schmidt TM | Neuron | 30017393 | Neuron | 2018 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/30017393 |
Overlapping morphological and functional properties between M4 and M5 intrinsically photosensitive retinal ganglion cells. | Sonoda T, Okabe Y, Schmidt TM | The Journal of comparative neurology | 31691279 | J Comp Neurol | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31691279 |
Cellular properties of intrinsically photosensitive retinal ganglion cells during postnatal development. | Lucas JA, Schmidt TM | Neural development | 31470901 | Neural Dev | 2019 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/31470901 |
M1 Intrinsically Photosensitive Retinal Ganglion Cells Integrate Rod and Melanopsin Inputs to Signal in Low Light. | Lee SK, Sonoda T, Schmidt TM | Cell reports | 31825819 | Cell Rep | 2019 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/31825819 |
Melanopsin activates divergent phototransduction pathways in intrinsically photosensitive retinal ganglion cell subtypes. | Contreras E, Bhoi JD, Sonoda T, Birnbaumer L, Schmidt TM | eLife | 37937828 | Elife | 2023 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/37937828 |
A noncanonical inhibitory circuit dampens behavioral sensitivity to light. | Sonoda T, Li JY, Hayes NW, Chan JC, Okabe Y, Belin S, Nawabi H, Schmidt TM | Science (New York, N.Y.) | 32355031 | Science | 2020 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/32355031 |
Distinct ipRGC subpopulations mediate light's acute and circadian effects on body temperature and sleep. | Rupp AC, Ren M, Altimus CM, Fernandez DC, Richardson M, Turek F, Hattar S, Schmidt TM | eLife | 31333190 | Elife | 2019 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/31333190 |
Diversity of intrinsically photosensitive retinal ganglion cells: circuits and functions. | Aranda ML, Schmidt TM | Cellular and molecular life sciences : CMLS | 32965515 | Cell Mol Life Sci | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32965515 |
Melanopsin phototransduction: beyond canonical cascades. | Contreras E, Nobleman AP, Robinson PR, Schmidt TM | The Journal of experimental biology | 34842918 | J Exp Biol | 2021 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/34842918 |
The dynamic receptive fields of retinal ganglion cells. | Wienbar S, Schwartz GW | Progress in retinal and eye research | 29944919 | Prog Retin Eye Res | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/29944919 |
Cardinal Orientation Selectivity Is Represented by Two Distinct Ganglion Cell Types in Mouse Retina. | Nath A, Schwartz GW | The Journal of neuroscience : the official journal of the Society for Neuroscience | 26985031 | J Neurosci | 2016 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/26985031 |
Three Small-Receptive-Field Ganglion Cells in the Mouse Retina Are Distinctly Tuned to Size, Speed, and Object Motion. | Jacoby J, Schwartz GW | The Journal of neuroscience : the official journal of the Society for Neuroscience | 28100743 | J Neurosci | 2017 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/28100743 |
An Amacrine Cell Circuit for Signaling Steady Illumination in the Retina. | Jacoby J, Zhu Y, DeVries SH, Schwartz GW | Cell reports | 26711334 | Cell Rep | 2015 Dec 29 | https://www.ncbi.nlm.nih.gov/pubmed/26711334 |
Circuit Mechanisms of a Retinal Ganglion Cell with Stimulus-Dependent Response Latency and Activation Beyond Its Dendrites. | Mani A, Schwartz GW | Current biology : CB | 28132812 | Curr Biol | 2017 Feb 20 | https://www.ncbi.nlm.nih.gov/pubmed/28132812 |
Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells. | D'Souza SP, Swygart DI, Wienbar SR, Upton BA, Zhang KX, Mackin RD, Casasent AK, Samuel MA, Schwartz GW, Lang RA | The Journal of comparative neurology | 34743323 | J Comp Neurol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34743323 |
An offset ON-OFF receptive field is created by gap junctions between distinct types of retinal ganglion cells. | Cooler S, Schwartz GW | Nature neuroscience | 33230322 | Nat Neurosci | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33230322 |
Molecular signatures of retinal ganglion cells revealed through single cell profiling. | Laboissonniere LA, Goetz JJ, Martin GM, Bi R, Lund TJS, Ellson L, Lynch MR, Mooney B, Wickham H, Liu P, Schwartz GW, Trimarchi JM | Scientific reports | 31673015 | Sci Rep | 2019 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/31673015 |
A Self-Regulating Gap Junction Network of Amacrine Cells Controls Nitric Oxide Release in the Retina. | Jacoby J, Nath A, Jessen ZF, Schwartz GW | Neuron | 30482690 | Neuron | 2018 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/30482690 |
Electrical synapses convey orientation selectivity in the mouse retina. | Nath A, Schwartz GW | Nature communications | 29229967 | Nat Commun | 2017 Dec 11 | https://www.ncbi.nlm.nih.gov/pubmed/29229967 |
Differences in spike generation instead of synaptic inputs determine the feature selectivity of two retinal cell types. | Wienbar S, Schwartz GW | Neuron | 35508174 | Neuron | 2022 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/35508174 |
Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele. | Parmhans N, Fuller AD, Nguyen E, Chuang K, Swygart D, Wienbar SR, Lin T, Kozmik Z, Dong L, Schwartz GW, Badea TC | The Journal of comparative neurology | 33135183 | J Comp Neurol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33135183 |
Unified classification of mouse retinal ganglion cells using function, morphology, and gene expression. | Goetz J, Jessen ZF, Jacobi A, Mani A, Cooler S, Greer D, Kadri S, Segal J, Shekhar K, Sanes JR, Schwartz GW | Cell reports | 35830791 | Cell Rep | 2022 Jul 12 | https://www.ncbi.nlm.nih.gov/pubmed/35830791 |
Low-Dimensional Spatiotemporal Dynamics Underlie Cortex-wide Neural Activity. | MacDowell CJ, Buschman TJ | Current biology : CB | 32470366 | Curr Biol | 2020 Jul 20 | https://www.ncbi.nlm.nih.gov/pubmed/32470366 |
From Behavior to Neural Dynamics: An Integrated Theory of Attention. | Buschman TJ, Kastner S | Neuron | 26447577 | Neuron | 2015 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/26447577 |
Rotational dynamics reduce interference between sensory and memory representations. | Libby A, Buschman TJ | Nature neuroscience | 33821001 | Nat Neurosci | 2021 May | https://www.ncbi.nlm.nih.gov/pubmed/33821001 |
Learning to control the brain through adaptive closed-loop patterned stimulation. | Tafazoli S, MacDowell CJ, Che Z, Letai KC, Steinhardt CR, Buschman TJ | Journal of neural engineering | 32927437 | J Neural Eng | 2020 Oct 13 | https://www.ncbi.nlm.nih.gov/pubmed/32927437 |
Differences in the expression of cortex-wide neural dynamics are related to behavioral phenotype. | MacDowell CJ, Briones BA, Lenzi MJ, Gustison ML, Buschman TJ | Current biology : CB | 38417445 | Curr Biol | 2024 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/38417445 |
Mouse Higher Visual Areas Provide Both Distributed and Specialized Contributions to Visually Guided Behaviors. | Jin M, Glickfeld LL | Current biology : CB | 33035487 | Curr Biol | 2020 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/33035487 |
Distinct recruitment of feedforward and recurrent pathways across higher-order areas of mouse visual cortex. | Li JY, Hass CA, Matthews I, Kristl AC, Glickfeld LL | Current biology : CB | 34637748 | Curr Biol | 2021 Nov 22 | https://www.ncbi.nlm.nih.gov/pubmed/34637748 |
Magnitude, time course, and specificity of rapid adaptation across mouse visual areas. | Jin M, Glickfeld LL | Journal of neurophysiology | 32584636 | J Neurophysiol | 2020 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/32584636 |
Higher-Order Areas of the Mouse Visual Cortex. | Glickfeld LL, Olsen SR | Annual review of vision science | 28746815 | Annu Rev Vis Sci | 2017 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/28746815 |
Neuronal Adaptation Reveals a Suboptimal Decoding of Orientation Tuned Populations in the Mouse Visual Cortex. | Jin M, Beck JM, Glickfeld LL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 30833509 | J Neurosci | 2019 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/30833509 |
Contribution of Sensory Encoding to Measured Bias. | Jin M, Glickfeld LL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 31015339 | J Neurosci | 2019 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/31015339 |
High-fidelity optical excitation of cortico-cortical projections at physiological frequencies. | Hass CA, Glickfeld LL | Journal of neurophysiology | 27489370 | J Neurophysiol | 2016 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/27489370 |
Unique Spatial Integration in Mouse Primary Visual Cortex and Higher Visual Areas. | Murgas KA, Wilson AM, Michael V, Glickfeld LL | The Journal of neuroscience : the official journal of the Society for Neuroscience | 31949109 | J Neurosci | 2020 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/31949109 |
Neuregulin-1/ErbB4 Signaling Regulates Visual Cortical Plasticity. | Sun Y, Ikrar T, Davis MF, Gong N, Zheng X, Luo ZD, Lai C, Mei L, Holmes TC, Gandhi SP, Xu X | Neuron | 27641496 | Neuron | 2016 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/27641496 |
Contralateral Bias of High Spatial Frequency Tuning and Cardinal Direction Selectivity in Mouse Visual Cortex. | Salinas KJ, Figueroa Velez DX, Zeitoun JH, Kim H, Gandhi SP | The Journal of neuroscience : the official journal of the Society for Neuroscience | 28924011 | J Neurosci | 2017 Oct 18 | https://www.ncbi.nlm.nih.gov/pubmed/28924011 |
Precocious deposition of perineuronal nets on Parvalbumin inhibitory neurons transplanted into adult visual cortex. | Bradshaw KP, Figueroa Velez DX, Habeeb M, Gandhi SP | Scientific reports | 29748633 | Sci Rep | 2018 May 10 | https://www.ncbi.nlm.nih.gov/pubmed/29748633 |
Inhibitory Neuron Transplantation into Adult Visual Cortex Creates a New Critical Period that Rescues Impaired Vision. | Davis MF, Figueroa Velez DX, Guevarra RP, Yang MC, Habeeb M, Carathedathu MC, Gandhi SP | Neuron | 25937171 | Neuron | 2015 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/25937171 |
Long-term Monocular Deprivation during Juvenile Critical Period Disrupts Binocular Integration in Mouse Visual Thalamus. | Huh CYL, Abdelaal K, Salinas KJ, Gu D, Zeitoun J, Figueroa Velez DX, Peach JP, Fowlkes CC, Gandhi SP | The Journal of neuroscience : the official journal of the Society for Neuroscience | 31767678 | J Neurosci | 2020 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/31767678 |
Functional Differentiation of Mouse Visual Cortical Areas Depends upon Early Binocular Experience. | Salinas KJ, Huh CYL, Zeitoun JH, Gandhi SP | The Journal of neuroscience : the official journal of the Society for Neuroscience | 33376158 | J Neurosci | 2021 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/33376158 |
Contribution of Innate Cortical Mechanisms to the Maturation of Orientation Selectivity in Parvalbumin Interneurons. | Figueroa Velez DX, Ellefsen KL, Hathaway ER, Carathedathu MC, Gandhi SP | The Journal of neuroscience : the official journal of the Society for Neuroscience | 28123018 | J Neurosci | 2017 Jan 25 | https://www.ncbi.nlm.nih.gov/pubmed/28123018 |
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Protein-altering variants at copy number-variable regions influence diverse human phenotypes. | Hujoel MLA, Handsaker RE, Sherman MA, Kamitaki N, Barton AR, Mukamel RE, Terao C, McCarroll SA, Loh PR | Nature genetics | 38548989 | Nat Genet | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38548989 |
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Protein-coding repeat polymorphisms strongly shape diverse human phenotypes. | Mukamel RE, Handsaker RE, Sherman MA, Barton AR, Zheng Y, McCarroll SA, Loh PR | Science (New York, N.Y.) | 34554798 | Science | 2021 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/34554798 |
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Hidden protein-altering variants influence diverse human phenotypes. | Hujoel MLA, Handsaker RE, Sherman MA, Kamitaki N, Barton AR, Mukamel RE, Terao C, McCarroll SA, Loh PR | bioRxiv : the preprint server for biology | 37333244 | bioRxiv | 2023 Jun 9 | https://www.ncbi.nlm.nih.gov/pubmed/37333244 |
A sequence of SVA retrotransposon insertions in ASIP shaped human pigmentation. | Kamitaki N, Hujoel MLA, Mukamel RE, Gebara E, McCarroll SA, Loh PR | Nature genetics | 39048794 | Nat Genet | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/39048794 |
Monogenic and polygenic inheritance become instruments for clonal selection. | Loh PR, Genovese G, McCarroll SA | Nature | 32581363 | Nature | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32581363 |
Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer. | Zekavat SM, Lin SH, Bick AG, Liu A, Paruchuri K, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Pirruccello JP, Pampana A, Loh PR, Kohli P, McCarroll SA, Neale B, Engels EA, Brown DW, Smoller JW, Green R, Karlson EW, Lebo M, Ellinor PT, Weiss ST, Daly MJ, Biobank Japan Project, FinnGen Consortium, Terao C, Zhao H, Ebert BL, COVID-19 Host Genetics Initiative, Ganna A, Machiela MJ, Genovese G, Natarajan P | medRxiv : the preprint server for health sciences | 33236019 | medRxiv | 2020 Nov 16 | https://www.ncbi.nlm.nih.gov/pubmed/33236019 |
Chromosomal alterations among age-related haematopoietic clones in Japan. | Terao C, Suzuki A, Momozawa Y, Akiyama M, Ishigaki K, Yamamoto K, Matsuda K, Murakami Y, McCarroll SA, Kubo M, Loh PR, Kamatani Y | Nature | 32581364 | Nature | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32581364 |
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Autosomal recessive progeroid syndrome due to homozygosity for a TOMM7 variant. | Garg A, Keng WT, Chen Z, Sathe AA, Xing C, Kailasam PD, Shao Y, Lesner NP, Llamas CB, Agarwal AK, Mishra P | The Journal of clinical investigation | 36282599 | J Clin Invest | 2022 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/36282599 |
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Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis. | Shelton SD, House S, Martins Nascentes Melo L, Ramesh V, Chen Z, Wei T, Wang X, Llamas CB, Venigalla SSK, Menezes CJ, Allies G, Krystkiewicz J, Rösler J, Meckelmann SW, Zhao P, Rambow F, Schadendorf D, Zhao Z, Gill JG, DeBerardinis RJ, Morrison SJ, Tasdogan A, Mishra P | Science advances | 39485847 | Sci Adv | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39485847 |
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Lactate metabolism is essential in early-onset mitochondrial myopathy. | Chen Z, Bordieanu B, Kesavan R, Lesner NP, Venigalla SSK, Shelton SD, DeBerardinis RJ, Mishra P | Science advances | 36598990 | Sci Adv | 2023 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/36598990 |
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy. | Gok MO, Connor OM, Wang X, Menezes CJ, Llamas CB, Mishra P, Friedman JR | The Journal of cell biology | 36795401 | J Cell Biol | 2023 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/36795401 |
Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis. | Shelton SD, House S, Ramesh V, Chen Z, Wei T, Wang X, Llamas CB, Venigalla SSK, Menezes CJ, Zhao Z, Gill JG, DeBerardinis RJ, Morrison SJ, Tasdogan A, Mishra P | bioRxiv : the preprint server for biology | 37732192 | bioRxiv | 2023 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/37732192 |
Differential requirements for mitochondrial electron transport chain components in the adult murine liver. | Lesner NP, Wang X, Chen Z, Frank A, Menezes CJ, House S, Shelton SD, Lemoff A, McFadden DG, Wansapura J, DeBerardinis RJ, Mishra P | eLife | 36154948 | Elife | 2022 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/36154948 |
Fusion of dysfunction muscle stem cells with myofibers induces sarcopenia in mice. | Wang X, Mishra P | bioRxiv : the preprint server for biology | 36711602 | bioRxiv | 2023 Jan 21 | https://www.ncbi.nlm.nih.gov/pubmed/36711602 |
Metabolic inflexibility promotes mitochondrial health during liver regeneration. | Wang X, Menezes CJ, Jia Y, Xiao Y, Venigalla SSK, Cai F, Hsieh MH, Gu W, Du L, Sudderth J, Kim D, Shelton SD, Llamas CB, Lin YH, Zhu M, Merchant S, Bezwada D, Kelekar S, Zacharias LG, Mathews TP, Hoxhaj G, Wynn RM, Tambar UK, DeBerardinis RJ, Zhu H, Mishra P | Science (New York, N.Y.) | 38870309 | Science | 2024 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/38870309 |
Bioorthogonal Retro-Cope Elimination Reaction of N,N-Dialkylhydroxylamines and Strained Alkynes. | Kang D, Kim J | Journal of the American Chemical Society | 33829777 | J Am Chem Soc | 2021 Apr 21 | https://www.ncbi.nlm.nih.gov/pubmed/33829777 |
Enamine N-oxides: Design, Synthesis, and Function in Bioorthogonal Reactions. | Kang D, Kim J | Synlett : accounts and rapid communications in synthetic organic chemistry | 38947226 | Synlett | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/38947226 |
Bioorthogonal Click and Release: A General, Rapid, Chemically Revertible Bioconjugation Strategy Employing Enamine N-oxides. | Kang D, Lee S, Kim J | Chem | 36176744 | Chem | 2022 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/36176744 |
Enamine N-Oxides: Synthesis and Application to Hypoxia-Responsive Prodrugs and Imaging Agents. | Kang D, Cheung ST, Wong-Rolle A, Kim J | ACS central science | 34056093 | ACS Cent Sci | 2021 Apr 28 | https://www.ncbi.nlm.nih.gov/pubmed/34056093 |
Bioorthogonally activated reactive species for target identification. | Siriwongsup S, Schmoker AM, Ficarro SB, Marto JA, Kim J | Chem | 38617077 | Chem | 2024 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/38617077 |
Bioorthogonal Hydroamination of Push-Pull-Activated Linear Alkynes. | Kang D, Cheung ST, Kim J | Angewandte Chemie (International ed. in English) | 34019705 | Angew Chem Int Ed Engl | 2021 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/34019705 |
Synthesis of push-pull-activated ynol ethers and their evaluation in the bioorthogonal hydroamination reaction. | Kang D, Wahl C, Kim J | Organic & biomolecular chemistry | 36367436 | Org Biomol Chem | 2022 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/36367436 |
Tissue clearing and its applications in neuroscience. | Ueda HR, Ertürk A, Chung K, Gradinaru V, Chédotal A, Tomancak P, Keller PJ | Nature reviews. Neuroscience | 31896771 | Nat Rev Neurosci | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31896771 |
Protection of tissue physicochemical properties using polyfunctional crosslinkers. | Park YG, Sohn CH, Chen R, McCue M, Yun DH, Drummond GT, Ku T, Evans NB, Oak HC, Trieu W, Choi H, Jin X, Lilascharoen V, Wang J, Truttmann MC, Qi HW, Ploegh HL, Golub TR, Chen SC, Frosch MP, Kulik HJ, Lim BK, Chung K | Nature biotechnology | 30556815 | Nat Biotechnol | 2018 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/30556815 |
Depolarization signatures map gold nanorods within biological tissue. | Lippok N, Villiger M, Albanese A, Meijer EFJ, Chung K, Padera TP, Bhatia SN, Bouma BE | Nature photonics | 29201136 | Nat Photonics | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29201136 |
Integrated platform for multiscale molecular imaging and phenotyping of the human brain. | Park J, Wang J, Guan W, Gjesteby LA, Pollack D, Kamentsky L, Evans NB, Stirman J, Gu X, Zhao C, Marx S, Kim ME, Choi SW, Snyder M, Chavez D, Su-Arcaro C, Tian Y, Park CS, Zhang Q, Yun DH, Moukheiber M, Feng G, Yang XW, Keene CD, Hof PR, Ghosh SS, Frosch MP, Brattain LJ, Chung K | Science (New York, N.Y.) | 38870291 | Science | 2024 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/38870291 |
Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems. | Murray E, Cho JH, Goodwin D, Ku T, Swaney J, Kim SY, Choi H, Park YG, Park JY, Hubbert A, McCue M, Vassallo S, Bakh N, Frosch MP, Wedeen VJ, Seung HS, Chung K | Cell | 26638076 | Cell | 2015 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/26638076 |
Basic principles of hydrogel-based tissue transformation technologies and their applications. | Choi SW, Guan W, Chung K | Cell | 34358468 | Cell | 2021 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/34358468 |
Elasticizing tissues for reversible shape transformation and accelerated molecular labeling. | Ku T, Guan W, Evans NB, Sohn CH, Albanese A, Kim JG, Frosch MP, Chung K | Nature methods | 32424271 | Nat Methods | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32424271 |
Label-free volumetric optical imaging of intact murine brains. | Ren J, Choi H, Chung K, Bouma BE | Scientific reports | 28401897 | Sci Rep | 2017 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/28401897 |
Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions. | Roy DS, Park YG, Kim ME, Zhang Y, Ogawa SK, DiNapoli N, Gu X, Cho JH, Choi H, Kamentsky L, Martin J, Mosto O, Aida T, Chung K, Tonegawa S | Nature communications | 35379803 | Nat Commun | 2022 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/35379803 |
Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues. | Ku T, Swaney J, Park JY, Albanese A, Murray E, Cho JH, Park YG, Mangena V, Chen J, Chung K | Nature biotechnology | 27454740 | Nat Biotechnol | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27454740 |
Multiscale 3D phenotyping of human cerebral organoids. | Albanese A, Swaney JM, Yun DH, Evans NB, Antonucci JM, Velasco S, Sohn CH, Arlotta P, Gehrke L, Chung K | Scientific reports | 33293587 | Sci Rep | 2020 Dec 8 | https://www.ncbi.nlm.nih.gov/pubmed/33293587 |
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease. | Stevens KR, Scull MA, Ramanan V, Fortin CL, Chaturvedi RR, Knouse KA, Xiao JW, Fung C, Mirabella T, Chen AX, McCue MG, Yang MT, Fleming HE, Chung K, de Jong YP, Chen CS, Rice CM, Bhatia SN | Science translational medicine | 28724577 | Sci Transl Med | 2017 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/28724577 |
Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy. | Mano T, Albanese A, Dodt HU, Erturk A, Gradinaru V, Treweek JB, Miyawaki A, Chung K, Ueda HR | The Journal of neuroscience : the official journal of the Society for Neuroscience | 30381424 | J Neurosci | 2018 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/30381424 |
Npas4 Is a Critical Regulator of Learning-Induced Plasticity at Mossy Fiber-CA3 Synapses during Contextual Memory Formation. | Weng FJ, Garcia RI, Lutzu S, Alviña K, Zhang Y, Dushko M, Ku T, Zemoura K, Rich D, Garcia-Dominguez D, Hung M, Yelhekar TD, Sørensen AT, Xu W, Chung K, Castillo PE, Lin Y | Neuron | 29429933 | Neuron | 2018 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/29429933 |
Self-organized developmental patterning and differentiation in cerebral organoids. | Renner M, Lancaster MA, Bian S, Choi H, Ku T, Peer A, Chung K, Knoblich JA | The EMBO journal | 28283582 | EMBO J | 2017 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/28283582 |
Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. | Martorell AJ, Paulson AL, Suk HJ, Abdurrob F, Drummond GT, Guan W, Young JZ, Kim DN, Kritskiy O, Barker SJ, Mangena V, Prince SM, Brown EN, Chung K, Boyden ES, Singer AC, Tsai LH | Cell | 30879788 | Cell | 2019 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/30879788 |
TISSUE CLEARING. | Richardson DS, Guan W, Matsumoto K, Pan C, Chung K, Ertürk A, Ueda HR, Lichtman JW | Nature reviews. Methods primers | 35128463 | Nat Rev Methods Primers | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/35128463 |
Recent advances in simultaneous analysis of bisphenol A and its conjugates in human matrices: Exposure biomarker perspectives. | Andra SS, Austin C, Yang J, Patel D, Arora M | The Science of the total environment | 27586167 | Sci Total Environ | 2016 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/27586167 |
A multimodal imaging workflow to visualize metal mixtures in the human placenta and explore colocalization with biological response markers. | Niedzwiecki MM, Austin C, Remark R, Merad M, Gnjatic S, Estrada-Gutierrez G, Espejel-Nuñez A, Borboa-Olivares H, Guzman-Huerta M, Wright RJ, Wright RO, Arora M | Metallomics : integrated biometal science | 26987553 | Metallomics | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26987553 |
Comparison of multiple X-ray fluorescence techniques for elemental analysis of particulate matter collected on air filters. | Bilo F, Borgese L, Wambui A, Assi A, Zacco A, Federici S, Eichert DM, Tsuji K, Lucchini RG, Placidi D, Bontempi E, Depero LE | Journal of aerosol science | 30662085 | J Aerosol Sci | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/30662085 |
Elemental signatures of Australopithecus africanus teeth reveal seasonal dietary stress. | Joannes-Boyau R, Adams JW, Austin C, Arora M, Moffat I, Herries AIR, Tonge MP, Benazzi S, Evans AR, Kullmer O, Wroe S, Dosseto A, Fiorenza L | Nature | 31308534 | Nature | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31308534 |
Bayesian varying coefficient kernel machine regression to assess neurodevelopmental trajectories associated with exposure to complex mixtures. | Liu SH, Bobb JF, Claus Henn B, Gennings C, Schnaas L, Tellez-Rojo M, Bellinger D, Arora M, Wright RO, Coull BA | Statistics in medicine | 30277584 | Stat Med | 2018 Dec 30 | https://www.ncbi.nlm.nih.gov/pubmed/30277584 |
Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth. | Wahlberg K, Arora M, Curtin A, Curtin P, Wright RO, Smith DR, Lucchini RG, Broberg K, Austin C | Neurotoxicology | 28917719 | Neurotoxicology | 2018 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28917719 |
Stress exposure histories revealed by biochemical changes along accentuated lines in teeth. | Austin C, Kumar P, Carter EA, Lee J, Smith TM, Hinde K, Arora M, Lay PA | Chemosphere | 37054846 | Chemosphere | 2023 Jul | https://www.ncbi.nlm.nih.gov/pubmed/37054846 |
Sex differences in sensitivity to prenatal and early childhood manganese exposure on neuromotor function in adolescents. | Chiu YM, Claus Henn B, Hsu HL, Pendo MP, Coull BA, Austin C, Cagna G, Fedrighi C, Placidi D, Smith DR, Wright RO, Lucchini RG, Arora M | Environmental research | 28858760 | Environ Res | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28858760 |
Dentine biomarkers of prenatal and early childhood exposure to manganese, zinc and lead and childhood behavior. | Horton MK, Hsu L, Claus Henn B, Margolis A, Austin C, Svensson K, Schnaas L, Gennings C, Hu H, Wright R, Rojo MMT, Arora M | Environment international | 30205321 | Environ Int | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30205321 |
Near-Infrared Intraoperative Chemiluminescence Imaging. | Büchel GE, Carney B, Shaffer TM, Tang J, Austin C, Arora M, Zeglis BM, Grimm J, Eppinger J, Reiner T | ChemMedChem | 27471800 | ChemMedChem | 2016 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/27471800 |
Fetal and postnatal metal dysregulation in autism. | Arora M, Reichenberg A, Willfors C, Austin C, Gennings C, Berggren S, Lichtenstein P, Anckarsäter H, Tammimies K, Bölte S | Nature communications | 28569757 | Nat Commun | 2017 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/28569757 |
Is poor oral health a risk marker for incident cardiovascular disease hospitalisation and all-cause mortality? Findings from 172 630 participants from the prospective 45 and Up Study. | Joshy G, Arora M, Korda RJ, Chalmers J, Banks E | BMJ open | 27577588 | BMJ Open | 2016 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/27577588 |
Manganese transporter genetics and sex modify the association between environmental manganese exposure and neurobehavioral outcomes in children. | Broberg K, Taj T, Guazzetti S, Peli M, Cagna G, Pineda D, Placidi D, Wright RO, Smith DR, Lucchini RG, Wahlberg K | Environment international | 31233999 | Environ Int | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31233999 |
The tooth exposome in children's health research. | Andra SS, Austin C, Arora M | Current opinion in pediatrics | 26859286 | Curr Opin Pediatr | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26859286 |
Uncovering neurodevelopmental windows of susceptibility to manganese exposure using dentine microspatial analyses. | Claus Henn B, Austin C, Coull BA, Schnaas L, Gennings C, Horton MK, Hernández-Ávila M, Hu H, Téllez-Rojo MM, Wright RO, Arora M | Environmental research | 29247915 | Environ Res | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29247915 |
Critical windows of susceptibility in the association between manganese and neurocognition in Italian adolescents living near ferro-manganese industry. | Bauer JA, White RF, Coull BA, Austin C, Oppini M, Zoni S, Fedrighi C, Cagna G, Placidi D, Guazzetti S, Yang Q, Bellinger DC, Webster TF, Wright RO, Smith D, Horton M, Lucchini RG, Arora M, Claus Henn B | Neurotoxicology | 34478771 | Neurotoxicology | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34478771 |
In utero metal exposures measured in deciduous teeth and birth outcomes in a racially-diverse urban cohort. | Cassidy-Bushrow AE, Wu KH, Sitarik AR, Park SK, Bielak LF, Austin C, Gennings C, Curtin P, Johnson CC, Arora M | Environmental research | 30735952 | Environ Res | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/30735952 |
Exposure to environmental chemical mixtures is associated with nasal colonization by Staphylococcus aureus: NHANES 2001-2004. | Eggers S, Gennings C, Malecki KMC, Safdar N, Arora M | Environmental research | 32771801 | Environ Res | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32771801 |
Prenatal and postnatal manganese teeth levels and neurodevelopment at 7, 9, and 10.5 years in the CHAMACOS cohort. | Mora AM, Arora M, Harley KG, Kogut K, Parra K, Hernández-Bonilla D, Gunier RB, Bradman A, Smith DR, Eskenazi B | Environment international | 26209874 | Environ Int | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26209874 |
Tooth matrix analysis for biomonitoring of organic chemical exposure: Current status, challenges, and opportunities. | Andra SS, Austin C, Arora M | Environmental research | 26219084 | Environ Res | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26219084 |
Reconstructing pre-natal and early childhood exposure to multi-class organic chemicals using teeth: Towards a retrospective temporal exposome. | Andra SS, Austin C, Wright RO, Arora M | Environment international | 26134987 | Environ Int | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26134987 |
Manganese in teeth and neurodevelopment in young Mexican-American children. | Gunier RB, Arora M, Jerrett M, Bradman A, Harley KG, Mora AM, Kogut K, Hubbard A, Austin C, Holland N, Eskenazi B | Environmental research | 26381693 | Environ Res | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26381693 |
Recurrence quantification analysis to characterize cyclical components of environmental elemental exposures during fetal and postnatal development. | Curtin P, Curtin A, Austin C, Gennings C, Tammimies K, Bölte S, Arora M | PloS one | 29112980 | PLoS One | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29112980 |
Uncovering system-specific stress signatures in primate teeth with multimodal imaging. | Austin C, Smith TM, Farahani RM, Hinde K, Carter EA, Lee J, Lay PA, Kennedy BJ, Sarrafpour B, Wright RJ, Wright RO, Arora M | Scientific reports | 26727334 | Sci Rep | 2016 Jan 4 | https://www.ncbi.nlm.nih.gov/pubmed/26727334 |
Cyclical nursing patterns in wild orangutans. | Smith TM, Austin C, Hinde K, Vogel ER, Arora M | Science advances | 28560319 | Sci Adv | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28560319 |
Extending the Distributed Lag Model framework to handle chemical mixtures. | Bello GA, Arora M, Austin C, Horton MK, Wright RO, Gennings C | Environmental research | 28371754 | Environ Res | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28371754 |
Burden of higher lead exposure in African-Americans starts in utero and persists into childhood. | Cassidy-Bushrow AE, Sitarik AR, Havstad S, Park SK, Bielak LF, Austin C, Johnson CC, Arora M | Environment international | 28886415 | Environ Int | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28886415 |
Manganese in teeth and neurobehavior: Sex-specific windows of susceptibility. | Bauer JA, Claus Henn B, Austin C, Zoni S, Fedrighi C, Cagna G, Placidi D, White RF, Yang Q, Coull BA, Smith D, Lucchini RG, Wright RO, Arora M | Environment international | 28941415 | Environ Int | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28941415 |
Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity. | Morishita H, Arora M | Trends in neurosciences | 28038829 | Trends Neurosci | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28038829 |
Tooth manganese as a biomarker of exposure and body burden in rats. | Austin C, Richardson C, Smith D, Arora M | Environmental research | 28279842 | Environ Res | 2017 May | https://www.ncbi.nlm.nih.gov/pubmed/28279842 |
Wintertime stress, nursing, and lead exposure in Neanderthal children. | Smith TM, Austin C, Green DR, Joannes-Boyau R, Bailey S, Dumitriu D, Fallon S, Grün R, James HF, Moncel MH, Williams IS, Wood R, Arora M | Science advances | 30402544 | Sci Adv | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30402544 |
Dynamical properties of elemental metabolism distinguish attention deficit hyperactivity disorder from autism spectrum disorder. | Austin C, Curtin P, Curtin A, Gennings C, Arora M, Tammimies K, Isaksson J, Willfors C, Bölte S | Translational psychiatry | 31551411 | Transl Psychiatry | 2019 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/31551411 |
Modeling the health effects of time-varying complex environmental mixtures: Mean field variational Bayes for lagged kernel machine regression. | Liu SH, Bobb JF, Claus Henn B, Schnaas L, Tellez-Rojo MM, Gennings C, Arora M, Wright RO, Coull BA, Wand MP | Environmetrics | 30686915 | Environmetrics | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30686915 |
Cross-sectional study of the association between serum perfluorinated alkyl acid concentrations and dental caries among US adolescents (NHANES 1999-2012). | Puttige Ramesh N, Arora M, Braun JM | BMJ open | 30782897 | BMJ Open | 2019 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/30782897 |
Dynamical features in fetal and postnatal zinc-copper metabolic cycles predict the emergence of autism spectrum disorder. | Curtin P, Austin C, Curtin A, Gennings C, Arora M, (for the Emergent Dynamical Systems Group), Tammimies K, Willfors C, Berggren S, Siper P, Rai D, Meyering K, Kolevzon A, Mollon J, David AS, Lewis G, Zammit S, Heilbrun L, Palmer RF, Wright RO, Bölte S, Reichenberg A | Science advances | 29854952 | Sci Adv | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29854952 |
Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice. | Morris-Schaffer K, Sobolewski M, Allen JL, Marvin E, Yee M, Arora M, O'Reilly MA, Cory-Slechta DA | Neurotoxicology | 29920326 | Neurotoxicology | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29920326 |
New Research Strategy for Measuring Pre- and Postnatal Metal Dysregulation in Psychotic Disorders. | Velthorst E, Smith L, Bello G, Austin C, Gennings C, Modabbernia A, Franke N, Frangou S, Wright R, de Haan L, Reichenberg A, Arora M | Schizophrenia bulletin | 28981868 | Schizophr Bull | 2017 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/28981868 |
Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis. | Curtin P, Austin C, Curtin A, Gennings C, Figueroa-Romero C, Mikhail KA, Botero TM, Goutman SA, Feldman EL, Arora M | PLoS computational biology | 32294079 | PLoS Comput Biol | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32294079 |
Multielemental bioimaging of tissues in children's environmental health research. | Austinc C, Niedzwiecki MM, Arora M | Current opinion in pediatrics | 26845145 | Curr Opin Pediatr | 2016 Apr | https://www.ncbi.nlm.nih.gov/pubmed/26845145 |
Early-life dentine manganese concentrations and intrinsic functional brain connectivity in adolescents: A pilot study. | de Water E, Papazaharias DM, Ambrosi C, Mascaro L, Iannilli E, Gasparotti R, Lucchini RG, Austin C, Arora M, Tang CY, Smith DR, Wright RO, Horton MK | PloS one | 31412061 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31412061 |
A Perspective on Crowdsourcing and Human-in-the-Loop Workflows in Precision Health. | Washington P | Journal of medical Internet research | 38602750 | J Med Internet Res | 2024 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/38602750 |
Audio-Based Emotion Recognition Using Self-Supervised Learning on an Engineered Feature Space. | Nimitsurachat P, Washington P | AI (Basel, Switzerland) | 38715564 | AI (Basel) | 2024 Mar | https://www.ncbi.nlm.nih.gov/pubmed/38715564 |
Digitally Diagnosing Multiple Developmental Delays Using Crowdsourcing Fused With Machine Learning: Protocol for a Human-in-the-Loop Machine Learning Study. | Jaiswal A, Kruiper R, Rasool A, Nandkeolyar A, Wall DP, Washington P | JMIR research protocols | 38329783 | JMIR Res Protoc | 2024 Feb 8 | https://www.ncbi.nlm.nih.gov/pubmed/38329783 |
Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design. | Li Y, Li N, Liu W, Prominski A, Kang S, Dai Y, Liu Y, Hu H, Wai S, Dai S, Cheng Z, Su Q, Cheng P, Wei C, Jin L, Hubbell JA, Tian B, Wang S | Nature communications | 37495580 | Nat Commun | 2023 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/37495580 |
Bioadhesive polymer semiconductors and transistors for intimate biointerfaces. | Li N, Li Y, Cheng Z, Liu Y, Dai Y, Kang S, Li S, Shan N, Wai S, Ziaja A, Wang Y, Strzalka J, Liu W, Zhang C, Gu X, Hubbell JA, Tian B, Wang S | Science (New York, N.Y.) | 37561870 | Science | 2023 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/37561870 |
Soft mechanical sensors for wearable and implantable applications. | Papani R, Li Y, Wang S | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 38723798 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2024 May-Jun | https://www.ncbi.nlm.nih.gov/pubmed/38723798 |
A Neuromorphic Brain Interface based on RRAM Crossbar Arrays for High Throughput Real-time Spike Sorting. | Shi Y, Ananthakrishnan A, Oh S, Liu X, Hota G, Cauwenberghs G, Kuzum D | IEEE transactions on electron devices | 37168652 | IEEE Trans Electron Devices | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/37168652 |
Energy-efficient Mott activation neuron for full-hardware implementation of neural networks. | Oh S, Shi Y, Del Valle J, Salev P, Lu Y, Huang Z, Kalcheim Y, Schuller IK, Kuzum D | Nature nanotechnology | 33737724 | Nat Nanotechnol | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33737724 |
Multimodal neural recordings with Neuro-FITM uncover diverse patterns of cortical-hippocampal interactions. | Liu X, Ren C, Lu Y, Liu Y, Kim JH, Leutgeb S, Komiyama T, Kuzum D | Nature neuroscience | 33875893 | Nat Neurosci | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33875893 |
Evaluation of Durability of Transparent Graphene Electrodes Fabricated on Different Flexible Substrates for Chronic In Vivo Experiments. | Ding D, Lu Y, Zhao R, Liu X, De-Eknamkul C, Ren C, Mehrsa A, Komiyama T, Kuzum D | IEEE transactions on bio-medical engineering | 32191878 | IEEE Trans Biomed Eng | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32191878 |
E-Cannula reveals anatomical diversity in sharp-wave ripples as a driver for the recruitment of distinct hippocampal assemblies. | Liu X, Terada S, Ramezani M, Kim JH, Lu Y, Grosmark A, Losonczy A, Kuzum D | Cell reports | 36198271 | Cell Rep | 2022 Oct 4 | https://www.ncbi.nlm.nih.gov/pubmed/36198271 |
Decoding of cortex-wide brain activity from local recordings of neural potentials. | Liu X, Ren C, Huang Z, Wilson M, Kim JH, Lu Y, Ramezani M, Komiyama T, Kuzum D | Journal of neural engineering | 34706356 | J Neural Eng | 2021 Nov 15 | https://www.ncbi.nlm.nih.gov/pubmed/34706356 |
High-density transparent graphene arrays for predicting cellular calcium activity at depth from surface potential recordings. | Ramezani M, Kim JH, Liu X, Ren C, Alothman A, De-Eknamkul C, Wilson MN, Cubukcu E, Gilja V, Komiyama T, Kuzum D | Nature nanotechnology | 38212523 | Nat Nanotechnol | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38212523 |
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. | Wilson MN, Thunemann M, Liu X, Lu Y, Puppo F, Adams JW, Kim JH, Ramezani M, Pizzo DP, Djurovic S, Andreassen OA, Mansour AA, Gage FH, Muotri AR, Devor A, Kuzum D | Nature communications | 36572698 | Nat Commun | 2022 Dec 26 | https://www.ncbi.nlm.nih.gov/pubmed/36572698 |
Electrochemical and electrophysiological considerations for clinical high channel count neural interfaces. | Vatsyayan R, Lee J, Bourhis AM, Tchoe Y, Cleary DR, Tonsfeldt KJ, Lee K, Montgomery-Walsh R, Paulk AC, U HS, Cash SS, Dayeh SA | MRS bulletin | 37476355 | MRS Bull | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37476355 |
Intraoperative application and early experience with novel high-resolution, high-channel-count thin-film electrodes for human microelectrocorticography. | Tan H, Paulk AC, Stedelin B, Cleary DR, Nerison C, Tchoe Y, Brown EC, Bourhis A, Russman S, Lee J, Tonsfeldt KJ, Yang JC, Oh H, Ro YG, Lee K, Ganji M, Galton I, Siler D, Han SJ, Collins KL, Ben-Haim S, Halgren E, Cash SS, Dayeh S, Raslan AM | Journal of neurosurgery | 37874692 | J Neurosurg | 2024 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/37874692 |
An Analytical Model for Dual Gate Piezoelectrically Sensitive ZnO Thin Film Transistors. | Oh H, Dayeh SA | Advanced materials technologies | 34485683 | Adv Mater Technol | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34485683 |
Surface-Grafted Biocompatible Polymer Conductors for Stable and Compliant Electrodes for Brain Interfaces. | Blau R, Russman SM, Qie Y, Shipley W, Lim A, Chen AX, Nyayachavadi A, Ah L, Abdal A, Esparza GL, Edmunds SJ, Vatsyayan R, Dunfield SP, Halder M, Jokerst JV, Fenning DP, Tao AR, Dayeh SA, Lipomi DJ | Advanced healthcare materials | 39011811 | Adv Healthc Mater | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/39011811 |
Human brain mapping with multithousand-channel PtNRGrids resolves spatiotemporal dynamics. | Tchoe Y, Bourhis AM, Cleary DR, Stedelin B, Lee J, Tonsfeldt KJ, Brown EC, Siler DA, Paulk AC, Yang JC, Oh H, Ro YG, Lee K, Russman SM, Ganji M, Galton I, Ben-Haim S, Raslan AM, Dayeh SA | Science translational medicine | 35044788 | Sci Transl Med | 2022 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/35044788 |
Microscale Physiological Events on the Human Cortical Surface. | Paulk AC, Yang JC, Cleary DR, Soper DJ, Halgren M, O'Donnell AR, Lee SH, Ganji M, Ro YG, Oh H, Hossain L, Lee J, Tchoe Y, Rogers N, Kiliç K, Ryu SB, Lee SW, Hermiz J, Gilja V, Ulbert I, Fabó D, Thesen T, Doyle WK, Devinsky O, Madsen JR, Schomer DL, Eskandar EN, Lee JW, Maus D, Devor A, Fried SI, Jones PS, Nahed BV, Ben-Haim S, Bick SK, Richardson RM, Raslan AM, Siler DA, Cahill DP, Williams ZM, Cosgrove GR, Dayeh SA, Cash SS | Cerebral cortex (New York, N.Y. : 1991) | 33749727 | Cereb Cortex | 2021 Jul 5 | https://www.ncbi.nlm.nih.gov/pubmed/33749727 |
Scalable tactile sensor arrays on flexible substrates with high spatiotemporal resolution enabling slip and grip for closed-loop robotics. | Oh H, Yi GC, Yip M, Dayeh SA | Science advances | 33188031 | Sci Adv | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33188031 |
Selective Formation of Porous Pt Nanorods for Highly Electrochemically Efficient Neural Electrode Interfaces. | Ganji M, Paulk AC, Yang JC, Vahidi NW, Lee SH, Liu R, Hossain L, Arneodo EM, Thunemann M, Shigyo M, Tanaka A, Ryu SB, Lee SW, Tchoe Y, Marsala M, Devor A, Cleary DR, Martin JR, Oh H, Gilja V, Gentner TQ, Fried SI, Halgren E, Cash SS, Dayeh SA | Nano letters | 31369283 | Nano Lett | 2019 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/31369283 |
Electrochemical safety limits for clinical stimulation investigated using depth and strip electrodes in the pig brain. | Vatsyayan R, Cleary D, Martin JR, Halgren E, Dayeh SA | Journal of neural engineering | 34015769 | J Neural Eng | 2021 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/34015769 |
Ultra-Sharp Nanowire Arrays Natively Permeate, Record, and Stimulate Intracellular Activity in Neuronal and Cardiac Networks. | Liu R, Lee J, Tchoe Y, Pre D, Bourhis AM, D'Antonio-Chronowska A, Robin G, Lee SH, Ro YG, Vatsyayan R, Tonsfeldt KJ, Hossain LA, Phipps ML, Yoo J, Nogan J, Martinez JS, Frazer KA, Bang AG, Dayeh SA | Advanced functional materials | 35603230 | Adv Funct Mater | 2022 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/35603230 |
Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation. | Gonzalez G, Nelson AC, Holman AR, Whitehead AJ, LaMontagne E, Lian R, Vatsyayan R, Dayeh SA, Engler AJ | Biomaterials | 37898021 | Biomaterials | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37898021 |
The Brain Electroencephalogram Microdisplay for Precision Neurosurgery. | Tchoe Y, Wu T, U HS, Roth DM, Kim D, Lee J, Cleary DR, Pizarro P, Tonsfeldt KJ, Lee K, Chen PC, Bourhis AM, Galton I, Coughlin B, Yang JC, Paulk AC, Halgren E, Cash SS, Dayeh SA | bioRxiv : the preprint server for biology | 37503216 | bioRxiv | 2023 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/37503216 |
Flexible, scalable, high channel count stereo-electrode for recording in the human brain. | Lee K, Paulk AC, Ro YG, Cleary DR, Tonsfeldt KJ, Kfir Y, Pezaris JS, Tchoe Y, Lee J, Bourhis AM, Vatsyayan R, Martin JR, Russman SM, Yang JC, Baohan A, Richardson RM, Williams ZM, Fried SI, Hoi Sang U, Raslan AM, Ben-Haim S, Halgren E, Cash SS, Dayeh SA | Nature communications | 38233418 | Nat Commun | 2024 Jan 17 | https://www.ncbi.nlm.nih.gov/pubmed/38233418 |
Syllable processing is organized in discrete subregions of the human superior temporal gyrus. | Cleary DR, Tchoe Y, Bourhis A, Dickey CW, Stedelin B, Ganji M, Lee SH, Lee J, Siler DA, Brown EC, Rosen BQ, Kaestner E, Yang JC, Soper DJ, Han SJ, Paulk AC, Cash SS, Raslan AM, Dayeh SA, Halgren E | PLoS biology | 39241107 | PLoS Biol | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39241107 |
Constructing 2D maps of human spinal cord activity and isolating the functional midline with high-density microelectrode arrays. | Russman SM, Cleary DR, Tchoe Y, Bourhis AM, Stedelin B, Martin J, Brown EC, Zhang X, Kawamoto A, Ryu WHA, Raslan AM, Ciacci JD, Dayeh SA | Science translational medicine | 36170445 | Sci Transl Med | 2022 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/36170445 |
Scalable Thousand Channel Penetrating Microneedle Arrays on Flex for Multimodal and Large Area Coverage BrainMachine Interfaces. | Lee SH, Thunemann M, Lee K, Cleary DR, Tonsfeldt KJ, Oh H, Azzazy F, Tchoe Y, Bourhis AM, Hossain L, Ro YG, Tanaka A, Kılıç K, Devor A, Dayeh SA | Advanced functional materials | 36381629 | Adv Funct Mater | 2022 Jun 17 | https://www.ncbi.nlm.nih.gov/pubmed/36381629 |
A Low-Noise Low-Power 0.001Hz-1kHz Neural Recording System-on-Chip With Sample-Level Duty-Cycling. | Wu J, Akinin A, Somayajulu J, Lee MS, Paul A, Lu H, Park Y, Kim SJ, Mercier PP, Cauwenberghs G | IEEE transactions on biomedical circuits and systems | 38408002 | IEEE Trans Biomed Circuits Syst | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38408002 |
Spatially confined responses of mouse visual cortex to intracortical magnetic stimulation from micro-coils. | Ryu SB, Paulk AC, Yang JC, Ganji M, Dayeh SA, Cash SS, Fried SI, Lee SW | Journal of neural engineering | 32998116 | J Neural Eng | 2020 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/32998116 |
A Comprehensive Large Signal, Small Signal, and Noise Model for IGZO Thin Film Transistor Circuits. | Vatsyayan R, Dayeh SA | IEEE transactions on electron devices | 37680851 | IEEE Trans Electron Devices | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37680851 |
Modular Phoneme Processing in Human Superior Temporal Gyrus. | Cleary DR, Tchoe Y, Bourhis A, Dickey CW, Stedelin B, Ganji M, Lee SH, Lee J, Siler DA, Brown EC, Rosen BQ, Kaestner E, Yang JC, Soper DJ, Han SJ, Paulk AC, Cash SS, Raslan AMT, Dayeh SA, Halgren E | bioRxiv : the preprint server for biology | 38293030 | bioRxiv | 2024 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/38293030 |
An electroencephalogram microdisplay to visualize neuronal activity on the brain surface. | Tchoe Y, Wu T, U HS, Roth DM, Kim D, Lee J, Cleary DR, Pizarro P, Tonsfeldt KJ, Lee K, Chen PC, Bourhis AM, Galton I, Coughlin B, Yang JC, Paulk AC, Halgren E, Cash SS, Dayeh SA | Science translational medicine | 38657026 | Sci Transl Med | 2024 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/38657026 |
Microscale dynamics of electrophysiological markers of epilepsy. | Yang JC, Paulk AC, Salami P, Lee SH, Ganji M, Soper DJ, Cleary D, Simon M, Maus D, Lee JW, Nahed BV, Jones PS, Cahill DP, Cosgrove GR, Chu CJ, Williams Z, Halgren E, Dayeh S, Cash SS | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology | 34419344 | Clin Neurophysiol | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34419344 |
Considerations and recent advances in nanoscale interfaces with neuronal and cardiac networks. | Tchoe Y, Lee J, Liu R, Bourhis AM, Vatsyayan R, Tonsfeldt KJ, Dayeh SA | Applied physics reviews | 34868443 | Appl Phys Rev | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34868443 |
Magnify is a universal molecular anchoring strategy for expansion microscopy. | Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y | Nature biotechnology | 36593399 | Nat Biotechnol | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/36593399 |
Expansion Microscopy: Toward Nanoscale Imaging of a Diverse Range of Biomolecules. | Klimas A, Zhao Y | ACS nano | 32628828 | ACS Nano | 2020 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/32628828 |
Super-Resolution Vibrational Imaging Using Expansion Stimulated Raman Scattering Microscopy. | Shi L, Klimas A, Gallagher B, Cheng Z, Fu F, Wijesekara P, Miao Y, Ren X, Zhao Y, Min W | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 35521971 | Adv Sci (Weinh) | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35521971 |
Basics of Expansion Microscopy. | Klimas A, Gallagher B, Zhao Y | Current protocols in cytometry | 31763769 | Curr Protoc Cytom | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/31763769 |
Expansion microscopy: A powerful nanoscale imaging tool for neuroscientists. | Gallagher BR, Zhao Y | Neurobiology of disease | 33813047 | Neurobiol Dis | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33813047 |
MicroMagnify: A Multiplexed Expansion Microscopy Method for Pathogens and Infected Tissues. | Cheng Z, Stefani C, Skillman T, Klimas A, Lee A, DiBernardo EF, Brown KM, Milman T, Wang Y, Gallagher BR, Lagree K, Jena BP, Pulido JS, Filler SG, Mitchell AP, Hiller NL, Lacy-Hulbert A, Zhao Y | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 37658522 | Adv Sci (Weinh) | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37658522 |
Nanoscale imaging of clinical specimens using conventional and rapid-expansion pathology. | Bucur O, Fu F, Calderon M, Mylvaganam GH, Ly NL, Day J, Watkin S, Walker BD, Boyden ES, Zhao Y | Nature protocols | 32238952 | Nat Protoc | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32238952 |
Reciprocal Signaling between Myeloid Derived Suppressor and Tumor Cells Enhances Cellular Motility and is Mediated by Structural Cues in the Microenvironment. | Shukla VC, Duarte-Sanmiguel S, Panic A, Senthilvelan A, Moore J, Bobba C, Benner B, Carson WE 3rd, Ghadiali SN, Gallego-Perez D | Advanced biosystems | 32419350 | Adv Biosyst | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32419350 |
In Situ Deployment of Engineered Extracellular Vesicles into the Tumor Niche via Myeloid-Derived Suppressor Cells. | Duarte-Sanmiguel S, Panic A, Dodd DJ, Salazar-Puerta A, Moore JT, Lawrence WR, Nairon K, Francis C, Zachariah N, McCoy W, Turaga R, Skardal A, Carson WE, Higuita-Castro N, Gallego-Perez D | Advanced healthcare materials | 34662497 | Adv Healthc Mater | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/34662497 |
Designer Extracellular Vesicles Modulate Pro-Neuronal Cell Responses and Improve Intracranial Retention. | Ortega-Pineda L, Sunyecz A, Salazar-Puerta AI, Rincon-Benavides MA, Alzate-Correa D, Anaparthi AL, Guilfoyle E, Mezache L, Struckman HL, Duarte-Sanmiguel S, Deng B, McComb DW, Dodd DJ, Lawrence WR, Moore J, Zhang J, Reátegui E, Veeraraghavan R, Nelson MT, Gallego-Perez D, Higuita-Castro N | Advanced healthcare materials | 35014204 | Adv Healthc Mater | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/35014204 |
Nanotransfection-based vasculogenic cell reprogramming drives functional recovery in a mouse model of ischemic stroke. | Lemmerman LR, Balch MHH, Moore JT, Alzate-Correa D, Rincon-Benavides MA, Salazar-Puerta A, Gnyawali S, Harris HN, Lawrence W, Ortega-Pineda L, Wilch L, Risser IB, Maxwell AJ, Duarte-Sanmiguel S, Dodd D, Guio-Vega GP, McTigue DM, Arnold WD, Nimjee SM, Sen CK, Khanna S, Rink C, Higuita-Castro N, Gallego-Perez D | Science advances | 33741587 | Sci Adv | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33741587 |
Engineered Vasculogenic Extracellular Vesicles Drive Nonviral Direct Conversions of Human Dermal Fibroblasts into Induced Endothelial Cells and Improve Wound Closure. | Rincon-Benavides MA, Mendonca NC, Cuellar-Gaviria TZ, Salazar-Puerta AI, Ortega-Pineda L, Blackstone BN, Deng B, McComb DW, Gallego-Perez D, Powell HM, Higuita-Castro N | Advanced therapeutics | 37577183 | Adv Ther (Weinh) | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/37577183 |
Nanomedicine-Based Strategies for Diabetes: Diagnostics, Monitoring, and Treatment. | Lemmerman LR, Das D, Higuita-Castro N, Mirmira RG, Gallego-Perez D | Trends in endocrinology and metabolism: TEM | 32396845 | Trends Endocrinol Metab | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32396845 |
Guided migration analyses at the single-clone level uncover cellular targets of interest in tumor-associated myeloid-derived suppressor cell populations. | Duarte-Sanmiguel S, Shukla V, Benner B, Moore J, Lemmerman L, Lawrence W, Panic A, Wang S, Idzkowski N, Guio-Vega G, Higuita-Castro N, Ghadiali S, Carson WE, Gallego-Perez D | Scientific reports | 31988310 | Sci Rep | 2020 Jan 27 | https://www.ncbi.nlm.nih.gov/pubmed/31988310 |
Transient Middle Cerebral Artery Occlusion with an Intraluminal Suture Enables Reproducible Induction of Ischemic Stroke in Mice. | Lemmerman LR, Harris HN, Balch MHH, Rincon-Benavides MA, Higuita-Castro N, Arnold DW, Gallego-Perez D | Bio-protocol | 35284595 | Bio Protoc | 2022 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/35284595 |
Nanotechnology-Driven Cell-Based Therapies in Regenerative Medicine. | Alzate-Correa D, Lawrence WR, Salazar-Puerta A, Higuita-Castro N, Gallego-Perez D | The AAPS journal | 35292878 | AAPS J | 2022 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/35292878 |
A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function. | Pinckard KM, Shettigar VK, Wright KR, Abay E, Baer LA, Vidal P, Dewal RS, Das D, Duarte-Sanmiguel S, Hernández-Saavedra D, Arts PJ, Lehnig AC, Bussberg V, Narain NR, Kiebish MA, Yi F, Sparks LM, Goodpaster BH, Smith SR, Pratley RE, Lewandowski ED, Raman SV, Wold LE, Gallego-Perez D, Coen PM, Ziolo MT, Stanford KI | Circulation | 33106031 | Circulation | 2021 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/33106031 |
ICAM-1-decorated extracellular vesicles loaded with miR-146a and Glut1 drive immunomodulation and hinder tumor progression in a murine model of breast cancer. | Duarte-Sanmiguel S, Salazar-Puerta AI, Panic A, Dodd D, Francis C, Alzate-Correa D, Ortega-Pineda L, Lemmerman L, Rincon-Benavides MA, Dathathreya K, Lawrence W, Ott N, Zhang J, Deng B, Wang S, Santander SP, McComb DW, Reategui E, Palmer AF, Carson WE, Higuita-Castro N, Gallego-Perez D | Biomaterials science | 37646133 | Biomater Sci | 2023 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/37646133 |
Injectable pulverized electrospun poly(lactic-co-glycolic acid) fibers improve human adipose tissue engraftment and volume retention. | Das D, Lawrence WR, Diaz-Starokozheva L, Salazar-Puerta AI, Ott N, Goebel ER, Damughatla A, Vidal P, Gallentine S, Moore JT, Kayuha D, Mendonca NC, Albert JB, Houser R, Johnson J, Powell H, Higuita-Castro N, Stanford KI, Gallego-Perez D | Journal of biomedical materials research. Part A | 37326365 | J Biomed Mater Res A | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37326365 |
Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles. | Cuellar-Gaviria TZ, Rincon-Benavides MA, Halipci Topsakal HN, Salazar-Puerta AI, Jaramillo-Garrido S, Kordowski M, Vasquez-Martinez CA, Nguyen KT, Rima XY, Rana PSJB, Combita-Heredia O, Deng B, Dathathreya K, McComb DW, Reategui E, Wozniak D, Higuita-Castro N, Gallego-Perez D | Journal of controlled release : official journal of the Controlled Release Society | 39491627 | J Control Release | 2024 Dec | https://www.ncbi.nlm.nih.gov/pubmed/39491627 |
Early Intervention in Ischemic Tissue with Oxygen Nanocarriers Enables Successful Implementation of Restorative Cell Therapies. | Diaz-Starokozheva L, Das D, Gu X, Moore JT, Lemmerman LR, Valerio I, Powell HM, Higuita-Castro N, Go MR, Palmer AF, Gallego-Perez D | Cellular and molecular bioengineering | 33184576 | Cell Mol Bioeng | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33184576 |
Nanochannel-Based Poration Drives Benign and Effective Nonviral Gene Delivery to Peripheral Nerve Tissue. | Moore JT, Wier CG, Lemmerman LR, Ortega-Pineda L, Dodd DJ, Lawrence WR, Duarte-Sanmiguel S, Dathathreya K, Diaz-Starokozheva L, Harris HN, Sen CK, Valerio IL, Higuita-Castro N, Arnold WD, Kolb SJ, Gallego-Perez D | Advanced biosystems | 32939985 | Adv Biosyst | 2020 Nov | https://www.ncbi.nlm.nih.gov/pubmed/32939985 |
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease. | Salazar-Puerta AI, Kordowski M, Cuellar-Gaviria TZ, Rincon-Benavides MA, Hussein J, Flemister D, Mayoral-Andrade G, Barringer G, Guilfoyle E, Blackstone BN, Deng B, Zepeda-Orozco D, McComb DW, Powell H, Dasi LP, Gallego-Perez D, Higuita-Castro N | Cellular and molecular bioengineering | 37810997 | Cell Mol Bioeng | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37810997 |
Engineered Extracellular Vesicles Derived from Dermal Fibroblasts Attenuate Inflammation in a Murine Model of Acute Lung Injury. | Salazar-Puerta AI, Rincon-Benavides MA, Cuellar-Gaviria TZ, Aldana J, Vasquez Martinez G, Ortega-Pineda L, Das D, Dodd D, Spencer CA, Deng B, McComb DW, Englert JA, Ghadiali S, Zepeda-Orozco D, Wold LE, Gallego-Perez D, Higuita-Castro N | Advanced materials (Deerfield Beach, Fla.) | 37119468 | Adv Mater | 2023 Jul | https://www.ncbi.nlm.nih.gov/pubmed/37119468 |
Engineered extracellular vesicles from human skin cells induce pro-β-cell conversions in pancreatic ductal cells. | Ortega-Pineda L, Guilfoyle E, Rincon-Benavides MA, Anaparthi AL, Lemmerman LR, Cuellar-Gaviria TZ, Lawrence W, Buss JL, Deng B, Blackstone BN, Salazar-Puerta A, McComb DW, Powell H, Gallego-Perez D, Higuita-Castro N | Advanced nanobiomed research | 38911285 | Adv Nanobiomed Res | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38911285 |
The Fifth Annual Symposium of the Midwest Aging Consortium. | Reader BF, Rosas L, Knopf BA, Liu Y, Alzate-Correa D, Bhat A, Carey A, Cuervo AM, Dayal S, Demarco RS, Elliehausen CJ, Englund DA, Hamilton HL, Johnston M, Kang P, Konopka AR, Lepola N, Presley CJ, Schafer MJ, Serrano J, Singer BD, Song MA, Stanford KI, Taylor J, Wei W, Yeh CY, Zhang L, Zhang L, Anderson RM, Bai H, Robbins PD, Lamming DW, Mihaylova MM, Rojas M, Mora AL | The journals of gerontology. Series A, Biological sciences and medical sciences | 39704343 | J Gerontol A Biol Sci Med Sci | 2025 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/39704343 |
3D-printed bioactive scaffolds from nanosilicates and PEOT/PBT for bone tissue engineering. | Carrow JK, Di Luca A, Dolatshahi-Pirouz A, Moroni L, Gaharwar AK | Regenerative biomaterials | 30740240 | Regen Biomater | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30740240 |
Printing Therapeutic Proteins in 3D using Nanoengineered Bioink to Control and Direct Cell Migration. | Peak CW, Singh KA, Adlouni M, Chen J, Gaharwar AK | Advanced healthcare materials | 31066517 | Adv Healthc Mater | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31066517 |
Intra-Articular Injectable Biomaterials for Cartilage Repair and Regeneration. | Kalairaj MS, Pradhan R, Saleem W, Smith MM, Gaharwar AK | Advanced healthcare materials | 38324655 | Adv Healthc Mater | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38324655 |
Dynamically crosslinked thermoresponsive granular hydrogels. | Lee HP, Cai KX, Wang TC, Davis R Jr, Deo K, Singh KA, Lele TP, Gaharwar AK | Journal of biomedical materials research. Part A | 37199446 | J Biomed Mater Res A | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/37199446 |
2D Covalent Organic Framework Direct Osteogenic Differentiation of Stem Cells. | Bhunia S, Jaiswal MK, Singh KA, Deo KA, Gaharwar AK | Advanced healthcare materials | 35104392 | Adv Healthc Mater | 2022 May | https://www.ncbi.nlm.nih.gov/pubmed/35104392 |
Inorganic Biomaterials Shape the Transcriptome Profile to Induce Endochondral Differentiation. | Murali A, Brokesh AM, Cross LM, Kersey AL, Jaiswal MK, Singh I, Gaharwar A | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 38738803 | Adv Sci (Weinh) | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/38738803 |
Atomic vacancies of molybdenum disulfide nanoparticles stimulate mitochondrial biogenesis. | Singh KA, Soukar J, Zulkifli M, Kersey A, Lokhande G, Ghosh S, Murali A, Garza NM, Kaur H, Keeney JN, Banavath R, Ceylan Koydemir H, Sitcheran R, Singh I, Gohil VM, Gaharwar AK | Nature communications | 39289340 | Nat Commun | 2024 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/39289340 |
Nanoengineered Colloidal Inks for 3D Bioprinting. | Peak CW, Stein J, Gold KA, Gaharwar AK | Langmuir : the ACS journal of surfaces and colloids | 28981287 | Langmuir | 2018 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/28981287 |
Gradient nanocomposite hydrogels for interface tissue engineering. | Cross LM, Shah K, Palani S, Peak CW, Gaharwar AK | Nanomedicine : nanotechnology, biology, and medicine | 28554596 | Nanomedicine | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28554596 |
Emerging 2D Nanomaterials for Biomedical Applications. | Murali A, Lokhande G, Deo KA, Brokesh A, Gaharwar AK | Materials today (Kidlington, England) | 34970073 | Mater Today (Kidlington) | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34970073 |
2D Nanoclay for Biomedical Applications: Regenerative Medicine, Therapeutic Delivery, and Additive Manufacturing. | Gaharwar AK, Cross LM, Peak CW, Gold K, Carrow JK, Brokesh A, Singh KA | Advanced materials (Deerfield Beach, Fla.) | 30941811 | Adv Mater | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30941811 |
Superhydrophobic states of 2D nanomaterials controlled by atomic defects can modulate cell adhesion. | Jaiswal MK , Singh KA , Lokhande G , Gaharwar AK | Chemical communications (Cambridge, England) | 31172998 | Chem Commun (Camb) | 2019 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/31172998 |
Dissociation of nanosilicates induces downstream endochondral differentiation gene expression program. | Brokesh AM, Cross LM, Kersey AL, Murali A, Richter C, Gregory CA, Singh I, Gaharwar AK | Science advances | 35476448 | Sci Adv | 2022 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/35476448 |
Inorganic ions activate lineage-specific gene regulatory networks. | Kersey AL, Singh I, Gaharwar AK | Acta biomaterialia | 38552761 | Acta Biomater | 2024 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/38552761 |
Organelle-Targeting Nanoparticles. | Soukar J, Peppas NA, Gaharwar AK | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 39806939 | Adv Sci (Weinh) | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39806939 |
Comparison of Photo Cross Linkable Gelatin Derivatives and Initiators for Three-Dimensional Extrusion Bioprinting. | Tigner TJ, Rajput S, Gaharwar AK, Alge DL | Biomacromolecules | 31743018 | Biomacromolecules | 2020 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/31743018 |
Photothermal modulation of human stem cells using light-responsive 2D nanomaterials. | Carrow JK, Singh KA, Jaiswal MK, Ramirez A, Lokhande G, Yeh AT, Sarkar TR, Singh I, Gaharwar AK | Proceedings of the National Academy of Sciences of the United States of America | 32461372 | Proc Natl Acad Sci U S A | 2020 Jun 16 | https://www.ncbi.nlm.nih.gov/pubmed/32461372 |
Nanoclay Reinforced Biomaterials for Mending Musculoskeletal Tissue Disorders. | Erezuma I, Eufrasio-da-Silva T, Golafshan N, Deo K, Mishra YK, Castilho M, Gaharwar AK, Leeuwenburgh S, Dolatshahi-Pirouz A, Orive G | Advanced healthcare materials | 34185438 | Adv Healthc Mater | 2021 Aug | https://www.ncbi.nlm.nih.gov/pubmed/34185438 |
Nano-bio interactions of 2D molybdenum disulfide. | Roy S, Deo KA, Singh KA, Lee HP, Jaiswal A, Gaharwar AK | Advanced drug delivery reviews | 35636569 | Adv Drug Deliv Rev | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35636569 |
2D layered nanomaterials for therapeutics delivery. | Davis R Jr, Urbanowski RA Jr, Gaharwar AK | Current opinion in biomedical engineering | 35814330 | Curr Opin Biomed Eng | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/35814330 |
Clickable PEG hydrogel microspheres as building blocks for 3D bioprinting. | Xin S , Chimene D , Garza JE , Gaharwar AK , Alge DL | Biomaterials science | 30656307 | Biomater Sci | 2019 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/30656307 |
Self-assembled, ellipsoidal polymeric nanoparticles for intracellular delivery of therapeutics. | Desai P, Venkataramanan A, Schneider R, Jaiswal MK, Carrow JK, Purwada A, Singh A, Gaharwar AK | Journal of biomedical materials research. Part A | 29577576 | J Biomed Mater Res A | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29577576 |
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs. | Kersey AL, Cheng DY, Deo KA, Dubell CR, Wang TC, Jaiswal MK, Kim MH, Murali A, Hargett SE, Mallick S, Lele TP, Singh I, Gaharwar AK | Biomaterials | 38335719 | Biomaterials | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38335719 |
Sustained and Prolonged Delivery of Protein Therapeutics from Two-Dimensional Nanosilicates. | Cross LM, Carrow JK, Ding X, Singh KA, Gaharwar AK | ACS applied materials & interfaces | 30676016 | ACS Appl Mater Interfaces | 2019 Feb 20 | https://www.ncbi.nlm.nih.gov/pubmed/30676016 |
Dynamically Cross-Linked Granular Hydrogels for 3D Printing and Therapeutic Delivery. | Lee HP, Davis R Jr, Wang TC, Deo KA, Cai KX, Alge DL, Lele TP, Gaharwar AK | ACS applied bio materials | 37584641 | ACS Appl Bio Mater | 2023 Sep 18 | https://www.ncbi.nlm.nih.gov/pubmed/37584641 |
Granular Biphasic Colloidal Hydrogels for 3D Bioprinting. | Deo KA, Murali A, Tronolone JJ, Mandrona C, Lee HP, Rajput S, Hargett SE, Selahi A, Sun Y, Alge DL, Jain A, Gaharwar AK | Advanced healthcare materials | 38749006 | Adv Healthc Mater | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38749006 |
Organ-on-chips made of blood: endothelial progenitor cells from blood reconstitute vascular thromboinflammation in vessel-chips. | Mathur T, Singh KA, R Pandian NK, Tsai SH, Hein TW, Gaharwar AK, Flanagan JM, Jain A | Lab on a chip | 31246211 | Lab Chip | 2019 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/31246211 |
Effect of ionic strength on shear-thinning nanoclay-polymer composite hydrogels. | Sheikhi A , Afewerki S , Oklu R , Gaharwar AK , Khademhosseini A | Biomaterials science | 29944151 | Biomater Sci | 2018 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/29944151 |
Emerging trends in multiscale modeling of vascular pathophysiology: Organ-on-a-chip and 3D printing. | Gold K, Gaharwar AK, Jain A | Biomaterials | 30072038 | Biomaterials | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30072038 |
Light-Responsive Inorganic Biomaterials for Biomedical Applications. | Lee HP, Gaharwar AK | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 32995121 | Adv Sci (Weinh) | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32995121 |
Conditioning of 3D Printed Nanoengineered Ionic-Covalent Entanglement Scaffolds with iP-hMSCs Derived Matrix. | Sears C, Mondragon E, Richards ZI, Sears N, Chimene D, McNeill EP, Gregory CA, Gaharwar AK, Kaunas R | Advanced healthcare materials | 32147960 | Adv Healthc Mater | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32147960 |
Nanoengineered Osteoinductive Bioink for 3D Bioprinting Bone Tissue. | Chimene D, Miller L, Cross LM, Jaiswal MK, Singh I, Gaharwar AK | ACS applied materials & interfaces | 32091189 | ACS Appl Mater Interfaces | 2020 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/32091189 |
Animal models of postpartum hemorrhage. | Hargett SE, Leslie EF, Chapa HO, Gaharwar AK | Lab animal | 38528231 | Lab Anim (NY) | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38528231 |
Nanoengineered Ink for Designing 3D Printable Flexible Bioelectronics. | Deo KA, Jaiswal MK, Abasi S, Lokhande G, Bhunia S, Nguyen TU, Namkoong M, Darvesh K, Guiseppi-Elie A, Tian L, Gaharwar AK | ACS nano | 35675588 | ACS Nano | 2022 Jun 28 | https://www.ncbi.nlm.nih.gov/pubmed/35675588 |
Generalizing hydrogel microparticles into a new class of bioinks for extrusion bioprinting. | Xin S, Deo KA, Dai J, Pandian NKR, Chimene D, Moebius RM, Jain A, Han A, Gaharwar AK, Alge DL | Science advances | 34652944 | Sci Adv | 2021 Oct 15 | https://www.ncbi.nlm.nih.gov/pubmed/34652944 |
3D Bioprinted Multicellular Vascular Models. | Gold KA, Saha B, Rajeeva Pandian NK, Walther BK, Palma JA, Jo J, Cooke JP, Jain A, Gaharwar AK | Advanced healthcare materials | 34310082 | Adv Healthc Mater | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34310082 |
Polymer-Coated Extracellular Vesicles for Selective Codelivery of Chemotherapeutics and siRNA to Cancer Cells. | Jhan YY, Palou Zuniga G, Singh KA, Gaharwar AK, Alge DL, Bishop CJ | ACS applied bio materials | 35014481 | ACS Appl Bio Mater | 2021 Feb 15 | https://www.ncbi.nlm.nih.gov/pubmed/35014481 |
Nanobio Interface Between Proteins and 2D Nanomaterials. | Roy S, Aastha, Deo KA, Dey K, Gaharwar AK, Jaiswal A | ACS applied materials & interfaces | 37487195 | ACS Appl Mater Interfaces | 2023 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/37487195 |
Nucleic acid delivery to mesenchymal stem cells: a review of nonviral methods and applications. | Hamann A, Nguyen A, Pannier AK | Journal of biological engineering | 30675180 | J Biol Eng | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30675180 |
Surface- and Hydrogel-Mediated Delivery of Nucleic Acid Nanoparticles. | Pannier AK, Kozisek T, Segura T | Methods in molecular biology (Clifton, N.J.) | 30838617 | Methods Mol Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30838617 |
Mechanisms of unprimed and dexamethasone-primed nonviral gene delivery to human mesenchymal stem cells. | Hamann A, Broad K, Nguyen A, Pannier AK | Biotechnology and bioengineering | 30450542 | Biotechnol Bioeng | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30450542 |
Free Polyethylenimine Enhances Substrate-Mediated Gene Delivery on Titanium Substrates Modified With RGD-Functionalized Poly(acrylic acid) Brushes. | Mantz A, Rosenthal A, Farris E, Kozisek T, Bittrich E, Nazari S, Schubert E, Schubert M, Stamm M, Uhlmann P, Pannier AK | Frontiers in chemistry | 30792979 | Front Chem | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/30792979 |
High-throughput screening of clinically approved drugs that prime nonviral gene delivery to human Mesenchymal stem cells. | Kozisek T, Hamann A, Nguyen A, Miller M, Plautz S, Pannier AK | Journal of biological engineering | 32467728 | J Biol Eng | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32467728 |
Innovative nonviral gene delivery strategies for engineering human mesenchymal stem cell phenotypes toward clinical applications. | Hamann A, Pannier AK | Current opinion in biotechnology | 36274497 | Curr Opin Biotechnol | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36274497 |
Biomaterial substrate modifications that influence cell-material interactions to prime cellular responses to nonviral gene delivery. | Mantz A, Pannier AK | Experimental biology and medicine (Maywood, N.J.) | 30621454 | Exp Biol Med (Maywood) | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30621454 |
High- and low-molecular-weight chitosan act as adjuvants during single-dose influenza A virus protein vaccination through distinct mechanisms. | Lampe AT, Farris EJ, Brown DM, Pannier AK | Biotechnology and bioengineering | 33289090 | Biotechnol Bioeng | 2021 Mar | https://www.ncbi.nlm.nih.gov/pubmed/33289090 |
Oral Non-Viral Gene Delivery for Applications in DNA Vaccination and Gene Therapy. | Farris E, Sanderfer K, Lampe A, Brown DM, Ramer-Tait AE, Pannier AK | Current opinion in biomedical engineering | 31011691 | Curr Opin Biomed Eng | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31011691 |
Systematic comparison of nonviral gene delivery strategies for efficient co-expression of two transgenes in human mesenchymal stem cells. | Kozisek T, Samuelson L, Hamann A, Pannier AK | Journal of biological engineering | 38062439 | J Biol Eng | 2023 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/38062439 |
Formulation of Chitosan-Zein Nano-in-Microparticles for Oral DNA Delivery. | Heck K, Farris E, Pannier AK | Methods in molecular biology (Clifton, N.J.) | 37775665 | Methods Mol Biol | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/37775665 |
Combined TLR4 and TLR9 agonists induce distinct phenotypic changes in innate immunity in vitro and in vivo. | Lampe AT, Puniya BL, Pannier AK, Helikar T, Brown DM | Cellular immunology | 32619809 | Cell Immunol | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32619809 |
Glucocorticoid Priming of Nonviral Gene Delivery to hMSCs Increases Transfection by Reducing Induced Stresses. | Hamann A, Kozisek T, Broad K, Pannier AK | Molecular therapy. Methods & clinical development | 32913879 | Mol Ther Methods Clin Dev | 2020 Sep 11 | https://www.ncbi.nlm.nih.gov/pubmed/32913879 |
Screening a chemically defined extracellular matrix mimetic substrate library to identify substrates that enhance substrate-mediated transfection. | Hamann A, Thomas AK, Kozisek T, Farris E, Lück S, Zhang Y, Pannier AK | Experimental biology and medicine (Maywood, N.J.) | 32183552 | Exp Biol Med (Maywood) | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32183552 |
Comparison of promoter, DNA vector, and cationic carrier for efficient transfection of hMSCs from multiple donors and tissue sources. | Kozisek T, Hamann A, Samuelson L, Fudolig M, Pannier AK | Molecular therapy. Nucleic acids | 34513295 | Mol Ther Nucleic Acids | 2021 Dec 3 | https://www.ncbi.nlm.nih.gov/pubmed/34513295 |
Lipid-based Liquid Crystalline Films and Solutions for the Delivery of Cargo to Cells. | Porras-Gomez M, Leal C | Liquid crystals reviews | 31942262 | Liq Cryst Rev | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31942262 |
Super-swelled lyotropic single crystals. | Kim H, Song Z, Leal C | Proceedings of the National Academy of Sciences of the United States of America | 28973884 | Proc Natl Acad Sci U S A | 2017 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/28973884 |
Self-organization of Nucleic Acids in Lipid Constructs. | Kang M, Kim H, Leal C | Current opinion in colloid & interface science | 28496379 | Curr Opin Colloid Interface Sci | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/28496379 |
Nanoscale partitioning of paclitaxel in hybrid lipid-polymer membranes. | Tuteja M , Kang M , Leal C , Centrone A | The Analyst | 29878001 | Analyst | 2018 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/29878001 |
3D Columnar Phase of Stacked Short DNA Organized by Coherent Membrane Undulations. | Bouxsein NF, Leal C, McAllister CS, Li Y, Ewert KK, Samuel CE, Safinya CR | Langmuir : the ACS journal of surfaces and colloids | 31408350 | Langmuir | 2019 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/31408350 |
Wirelessly controlled, bioresorbable drug delivery device with active valves that exploit electrochemically triggered crevice corrosion. | Koo J, Kim SB, Choi YS, Xie Z, Bandodkar AJ, Khalifeh J, Yan Y, Kim H, Pezhouh MK, Doty K, Lee G, Chen YY, Lee SM, D'Andrea D, Jung K, Lee K, Li K, Jo S, Wang H, Kim JH, Kim J, Choi SG, Jang WJ, Oh YS, Park I, Kwak SS, Park JH, Hong D, Feng X, Lee CH, Banks A, Leal C, Lee HM, Huang Y, Franz CK, Ray WZ, MacEwan M, Kang SK, Rogers JA | Science advances | 32923633 | Sci Adv | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32923633 |
The structural fate of lipid nanoparticles in the extracellular matrix. | Bandara SR, Molley TG, Kim H, Bharath PA, Kilian KA, Leal C | Materials horizons | 31942243 | Mater Horiz | 2020 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/31942243 |
Lipid nanoparticle topology regulates endosomal escape and delivery of RNA to the cytoplasm. | Zheng L, Bandara SR, Tan Z, Leal C | Proceedings of the National Academy of Sciences of the United States of America | 37364130 | Proc Natl Acad Sci U S A | 2023 Jul 4 | https://www.ncbi.nlm.nih.gov/pubmed/37364130 |
Near-Infrared-Triggered Reversible Transformations of Gold Nanorod-Laden Lipid Assemblies: Implications for Cellular Delivery. | Rueben J, Jayaraman A, Mahanthappa MK, Leal C | ACS applied nano materials | 40115494 | ACS Appl Nano Mater | 2022 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/40115494 |
Hybrid Unilamellar Vesicles of Phospholipids and Block Copolymers with Crystalline Domains. | Go YK, Kambar N, Leal C | Polymers | 32485809 | Polymers (Basel) | 2020 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/32485809 |
Thermally Functional Liquid Crystal Networks by Magnetic Field Driven Molecular Orientation. | Shin J, Kang M, Tsai T, Leal C, Braun PV, Cahill DG | ACS macro letters | 35607211 | ACS Macro Lett | 2016 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/35607211 |
Open-air synthesis of oligo(ethylene glycol)-functionalized polypeptides from non-purified N-carboxyanhydrides. | Tan Z, Song Z, Xue T, Zheng L, Jiang L, Jiang Y, Fu Z, Nguyen A, Leal C, Cheng J | Biomaterials science | 33949455 | Biomater Sci | 2021 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/33949455 |
Nanostructured Lipid-based Films for Substrate Mediated Applications in Biotechnology. | Kang M, Tuteja M, Centrone A, Topgaard D, Leal C | Advanced functional materials | 31080383 | Adv Funct Mater | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/31080383 |
Microfluidics Synthesis of Gene Silencing Cubosomes. | Kim H, Sung J, Chang Y, Alfeche A, Leal C | ACS nano | 30081623 | ACS Nano | 2018 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/30081623 |
Three-Dimensional Microphase Separation and Synergistic Permeability in Stacked Lipid-Polymer Hybrid Membranes. | Kang M, Lee B, Leal C | Chemistry of materials : a publication of the American Chemical Society | 31097879 | Chem Mater | 2017 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/31097879 |
The stabilization of primitive bicontinuous cubic phases with tunable swelling over a wide composition range. | Leung SSW , Leal C | Soft matter | 30462135 | Soft Matter | 2019 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/30462135 |
Graphene-based sensing of oxygen transport through pulmonary membranes. | Kim M, Porras-Gomez M, Leal C | Nature communications | 32107376 | Nat Commun | 2020 Feb 27 | https://www.ncbi.nlm.nih.gov/pubmed/32107376 |
Polymer-Lipid Hybrid Materials. | Go YK, Leal C | Chemical reviews | 34752064 | Chem Rev | 2021 Nov 24 | https://www.ncbi.nlm.nih.gov/pubmed/34752064 |
The Spatiotemporal Limits of Developmental Erk Signaling. | Johnson HE, Goyal Y, Pannucci NL, Schüpbach T, Shvartsman SY, Toettcher JE | Developmental cell | 28118601 | Dev Cell | 2017 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/28118601 |
P-Rex1 is dispensable for Erk activation and mitogenesis in breast cancer. | Barrio-Real L, Lopez-Haber C, Casado-Medrano V, Goglia AG, Toettcher JE, Caloca MJ, Kazanietz MG | Oncotarget | 29983884 | Oncotarget | 2018 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/29983884 |
Capicua is a fast-acting transcriptional brake. | Patel AL, Zhang L, Keenan SE, Rushlow CA, Fradin C, Shvartsman SY | Current biology : CB | 34166605 | Curr Biol | 2021 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/34166605 |
A bright future: optogenetics to dissect the spatiotemporal control of cell behavior. | Goglia AG, Toettcher JE | Current opinion in chemical biology | 30529586 | Curr Opin Chem Biol | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30529586 |
Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway. | Bugaj LJ, Sabnis AJ, Mitchell A, Garbarino JE, Toettcher JE, Bivona TG, Lim WA | Science (New York, N.Y.) | 30166458 | Science | 2018 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/30166458 |
Illuminating developmental biology with cellular optogenetics. | Johnson HE, Toettcher JE | Current opinion in biotechnology | 29505976 | Curr Opin Biotechnol | 2018 Aug | https://www.ncbi.nlm.nih.gov/pubmed/29505976 |
A Live-Cell Screen for Altered Erk Dynamics Reveals Principles of Proliferative Control. | Goglia AG, Wilson MZ, Jena SG, Silbert J, Basta LP, Devenport D, Toettcher JE | Cell systems | 32191874 | Cell Syst | 2020 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/32191874 |
Optogenetic control of protein binding using light-switchable nanobodies. | Gil AA, Carrasco-López C, Zhu L, Zhao EM, Ravindran PT, Wilson MZ, Goglia AG, Avalos JL, Toettcher JE | Nature communications | 32792536 | Nat Commun | 2020 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/32792536 |
Engineering combinatorial and dynamic decoders using synthetic immediate-early genes. | Ravindran PT, Wilson MZ, Jena SG, Toettcher JE | Communications biology | 32792645 | Commun Biol | 2020 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/32792645 |
Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli. | Dine E, Gil AA, Uribe G, Brangwynne CP, Toettcher JE | Cell systems | 29859829 | Cell Syst | 2018 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/29859829 |
Optogenetic Control of Ras/Erk Signaling Using the Phy-PIF System. | Goglia AG, Wilson MZ, DiGiorno DB, Toettcher JE | Methods in molecular biology (Clifton, N.J.) | 28730469 | Methods Mol Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28730469 |
Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control. | Wilson MZ, Ravindran PT, Lim WA, Toettcher JE | Molecular cell | 28826673 | Mol Cell | 2017 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/28826673 |
Substratum stiffness regulates Erk signaling dynamics through receptor-level control. | Farahani PE, Lemke SB, Dine E, Uribe G, Toettcher JE, Nelson CM | Cell reports | 34965432 | Cell Rep | 2021 Dec 28 | https://www.ncbi.nlm.nih.gov/pubmed/34965432 |
Light-based control of metabolic flux through assembly of synthetic organelles. | Zhao EM, Suek N, Wilson MZ, Dine E, Pannucci NL, Gitai Z, Avalos JL, Toettcher JE | Nature chemical biology | 31086330 | Nat Chem Biol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31086330 |
Optimizing photoswitchable MEK. | Patel AL, Yeung E, McGuire SE, Wu AY, Toettcher JE, Burdine RD, Shvartsman SY | Proceedings of the National Academy of Sciences of the United States of America | 31796593 | Proc Natl Acad Sci U S A | 2019 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/31796593 |
Dynamics of Drosophila endoderm specification. | Keenan SE, Avdeeva M, Yang L, Alber DS, Wieschaus EF, Shvartsman SY | Proceedings of the National Academy of Sciences of the United States of America | 35412853 | Proc Natl Acad Sci U S A | 2022 Apr 12 | https://www.ncbi.nlm.nih.gov/pubmed/35412853 |
Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors. | Mesev EV, Lin AE, Guare EG, Heller BL, Douam F, Adamson B, Toettcher JE, Ploss A | Science signaling | 37816090 | Sci Signal | 2023 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/37816090 |
Deconstructing and repurposing the light-regulated interplay between Arabidopsis phytochromes and interacting factors. | Golonka D, Fischbach P, Jena SG, Kleeberg JRW, Essen LO, Toettcher JE, Zurbriggen MD, Möglich A | Communications biology | 31815202 | Commun Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31815202 |
A size-invariant bud-duration timer enables robustness in yeast cell size control. | Allard CAH, Decker F, Weiner OD, Toettcher JE, Graziano BR | PloS one | 30576342 | PLoS One | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30576342 |
Design and Characterization of Rapid Optogenetic Circuits for Dynamic Control in Yeast Metabolic Engineering. | Zhao EM, Lalwani MA, Lovelett RJ, García-Echauri SA, Hoffman SM, Gonzalez CL, Toettcher JE, Kevrekidis IG, Avalos JL | ACS synthetic biology | 33232598 | ACS Synth Biol | 2020 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/33232598 |
Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold. | Carrasco-López C, Zhao EM, Gil AA, Alam N, Toettcher JE, Avalos JL | Nature communications | 32792484 | Nat Commun | 2020 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/32792484 |
A synthetic gene circuit for imaging-free detection of signaling pulses. | Ravindran PT, McFann S, Thornton RH, Toettcher JE | Cell systems | 34739875 | Cell Syst | 2022 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/34739875 |
Dynamical Modeling of Optogenetic Circuits in Yeast for Metabolic Engineering Applications. | Lovelett RJ, Zhao EM, Lalwani MA, Toettcher JE, Kevrekidis IG, L Avalos J | ACS synthetic biology | 33492138 | ACS Synth Biol | 2021 Feb 19 | https://www.ncbi.nlm.nih.gov/pubmed/33492138 |
Signaling, Deconstructed: Using Optogenetics to Dissect and Direct Information Flow in Biological Systems. | Farahani PE, Reed EH, Underhill EJ, Aoki K, Toettcher JE | Annual review of biomedical engineering | 33722063 | Annu Rev Biomed Eng | 2021 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/33722063 |
Optogenetic Amplification Circuits for Light-Induced Metabolic Control. | Zhao EM, Lalwani MA, Chen JM, Orillac P, Toettcher JE, Avalos JL | ACS synthetic biology | 33835777 | ACS Synth Biol | 2021 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/33835777 |
Erratum: Publisher Correction: Deconstructing and repurposing the light-regulated interplay between Arabidopsis phytochromes and interacting factors. | Golonka D, Fischbach P, Jena SG, Kleeberg JRW, Essen LO, Toettcher JE, Zurbriggen MD, Möglich A | Communications biology | 31872077 | Commun Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31872077 |
Signaling Dynamics Control Cell Fate in the Early Drosophila Embryo. | Johnson HE, Toettcher JE | Developmental cell | 30753836 | Dev Cell | 2019 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/30753836 |
Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds. | Bracha D, Walls MT, Wei MT, Zhu L, Kurian M, Avalos JL, Toettcher JE, Brangwynne CP | Cell | 30500534 | Cell | 2018 Nov 29 | https://www.ncbi.nlm.nih.gov/pubmed/30500534 |
Optogenetic regulation of engineered cellular metabolism for microbial chemical production. | Zhao EM, Zhang Y, Mehl J, Park H, Lalwani MA, Toettcher JE, Avalos JL | Nature | 29562237 | Nature | 2018 Mar 29 | https://www.ncbi.nlm.nih.gov/pubmed/29562237 |
Optogenetic Reconstitution for Determining the Form and Function of Membraneless Organelles. | Dine E, Toettcher JE | Biochemistry | 29373016 | Biochemistry | 2018 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/29373016 |
Four Key Steps Control Glycolytic Flux in Mammalian Cells. | Tanner LB, Goglia AG, Wei MH, Sehgal T, Parsons LR, Park JO, White E, Toettcher JE, Rabinowitz JD | Cell systems | 29960885 | Cell Syst | 2018 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/29960885 |
Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix. | Iuliano JN, Collado JT, Gil AA, Ravindran PT, Lukacs A, Shin S, Woroniecka HA, Adamczyk K, Aramini JM, Edupuganti UR, Hall CR, Greetham GM, Sazanovich IV, Clark IP, Daryaee T, Toettcher JE, French JB, Gardner KH, Simmerling CL, Meech SR, Tonge PJ | ACS chemical biology | 32880430 | ACS Chem Biol | 2020 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/32880430 |
Optogenetic Rescue of a Patterning Mutant. | Johnson HE, Djabrayan NJV, Shvartsman SY, Toettcher JE | Current biology : CB | 32707057 | Curr Biol | 2020 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/32707057 |
A self-exciting point process to study multicellular spatial signaling patterns. | Verma A, Jena SG, Isakov DR, Aoki K, Toettcher JE, Engelhardt BE | Proceedings of the National Academy of Sciences of the United States of America | 34362843 | Proc Natl Acad Sci U S A | 2021 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/34362843 |
Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch. | Dine E, Reed EH, Toettcher JE | Cell reports | 34161759 | Cell Rep | 2021 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/34161759 |
MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure. | Keren L, Bosse M, Thompson S, Risom T, Vijayaragavan K, McCaffrey E, Marquez D, Angoshtari R, Greenwald NF, Fienberg H, Wang J, Kambham N, Kirkwood D, Nolan G, Montine TJ, Galli SJ, West R, Bendall SC, Angelo M | Science advances | 31633026 | Sci Adv | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31633026 |
Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells. | Good Z, Borges L, Vivanco Gonzalez N, Sahaf B, Samusik N, Tibshirani R, Nolan GP, Bendall SC | Nature biotechnology | 30742126 | Nat Biotechnol | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30742126 |
Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy. | Hartmann FJ, Babdor J, Gherardini PF, Amir ED, Jones K, Sahaf B, Marquez DM, Krutzik P, O'Donnell E, Sigal N, Maecker HT, Meyer E, Spitzer MH, Bendall SC | Cell reports | 31315057 | Cell Rep | 2019 Jul 16 | https://www.ncbi.nlm.nih.gov/pubmed/31315057 |
Revealing new biology from multiplexed, metal-isotope-tagged, single-cell readouts. | Baskar R, Kimmey SC, Bendall SC | Trends in cell biology | 35181197 | Trends Cell Biol | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35181197 |
Unravelling human hematopoietic progenitor cell diversity through association with intrinsic regulatory factors. | Favaro P, Glass DR, Borges L, Baskar R, Reynolds W, Ho D, Bruce T, Tebaykin D, Scanlon VM, Shestopalov I, Bendall SC | bioRxiv : the preprint server for biology | 37693547 | bioRxiv | 2023 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/37693547 |
NK-like CD8(+) γδ T cells are expanded in persistent Mycobacterium tuberculosis infection. | Roy Chowdhury R, Valainis JR, Dubey M, von Boehmer L, Sola E, Wilhelmy J, Guo J, Kask O, Ohanyan M, Sun M, Huang H, Huang X, Nguyen PK, Scriba TJ, Davis MM, Bendall SC, Chien YH | Science immunology | 37000856 | Sci Immunol | 2023 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/37000856 |
A Universal Live Cell Barcoding-Platform for Multiplexed Human Single Cell Analysis. | Hartmann FJ, Simonds EF, Bendall SC | Scientific reports | 30018331 | Sci Rep | 2018 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/30018331 |
Reproducible, high-dimensional imaging in archival human tissue by multiplexed ion beam imaging by time-of-flight (MIBI-TOF). | Liu CC, Bosse M, Kong A, Kagel A, Kinders R, Hewitt SM, Varma S, van de Rijn M, Nowak SH, Bendall SC, Angelo M | Laboratory investigation; a journal of technical methods and pathology | 35351966 | Lab Invest | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35351966 |
Mass synaptometry: High-dimensional multi parametric assay for single synapses. | Gajera CR, Fernandez R, Postupna N, Montine KS, Fox EJ, Tebaykin D, Angelo M, Bendall SC, Keene CD, Montine TJ | Journal of neuroscience methods | 30465796 | J Neurosci Methods | 2019 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/30465796 |
Parallel analysis of tri-molecular biosynthesis with cell identity and function in single cells. | Kimmey SC, Borges L, Baskar R, Bendall SC | Nature communications | 30862852 | Nat Commun | 2019 Mar 12 | https://www.ncbi.nlm.nih.gov/pubmed/30862852 |
Scalable Conjugation and Characterization of Immunoglobulins with Stable Mass Isotope Reporters for Single-Cell Mass Cytometry Analysis. | Hartmann FJ, Simonds EF, Vivanco N, Bruce T, Borges L, Nolan GP, Spitzer MH, Bendall SC | Methods in molecular biology (Clifton, N.J.) | 31077099 | Methods Mol Biol | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31077099 |
Immune monitoring using mass cytometry and related high-dimensional imaging approaches. | Hartmann FJ, Bendall SC | Nature reviews. Rheumatology | 31892734 | Nat Rev Rheumatol | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31892734 |
The basis of cellular and regional vulnerability in Alzheimer's disease. | Mrdjen D, Fox EJ, Bukhari SA, Montine KS, Bendall SC, Montine TJ | Acta neuropathologica | 31392412 | Acta Neuropathol | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31392412 |
Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment. | Baskar R, Chen AF, Favaro P, Reynolds W, Mueller F, Borges L, Jiang S, Park HS, Kool ET, Greenleaf WJ, Bendall SC | Cell reports methods | 35463156 | Cell Rep Methods | 2022 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/35463156 |
Multiplexed single-cell morphometry for hematopathology diagnostics. | Tsai AG, Glass DR, Juntilla M, Hartmann FJ, Oak JS, Fernandez-Pol S, Ohgami RS, Bendall SC | Nature medicine | 32161403 | Nat Med | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/32161403 |
Mass Cytometry Phenotyping of Human Granulocytes Reveals Novel Basophil Functional Heterogeneity. | Vivanco Gonzalez N, Oliveria JP, Tebaykin D, Ivison GT, Mukai K, Tsai MM, Borges L, Nadeau KC, Galli SJ, Tsai AG, Bendall SC | iScience | 33205028 | iScience | 2020 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/33205028 |
Systems biology approaches to unravel lymphocyte subsets and function. | Kim Y, Greenleaf WJ, Bendall SC | Current opinion in immunology | 37028221 | Curr Opin Immunol | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/37028221 |
Mass-tag barcoding for multiplexed analysis of human synaptosomes and other anuclear events. | Gajera CR, Fernandez R, Montine KS, Fox EJ, Mrdjen D, Postupna NO, Keene CD, Bendall SC, Montine TJ | Cytometry. Part A : the journal of the International Society for Analytical Cytology | 33818911 | Cytometry A | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/33818911 |
A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging. | Keren L, Bosse M, Marquez D, Angoshtari R, Jain S, Varma S, Yang SR, Kurian A, Van Valen D, West R, Bendall SC, Angelo M | Cell | 30193111 | Cell | 2018 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/30193111 |
High-Parameter Immune Profiling with CyTOF. | Sahaf B, Rahman A, Maecker HT, Bendall SC | Methods in molecular biology (Clifton, N.J.) | 31502160 | Methods Mol Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/31502160 |
Single-cell metabolic profiling of human cytotoxic T cells. | Hartmann FJ, Mrdjen D, McCaffrey E, Glass DR, Greenwald NF, Bharadwaj A, Khair Z, Verberk SGS, Baranski A, Baskar R, Graf W, Van Valen D, Van den Bossche J, Angelo M, Bendall SC | Nature biotechnology | 32868913 | Nat Biotechnol | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32868913 |
An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity. | Glass DR, Tsai AG, Oliveria JP, Hartmann FJ, Kimmey SC, Calderon AA, Borges L, Glass MC, Wagar LE, Davis MM, Bendall SC | Immunity | 32668225 | Immunity | 2020 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/32668225 |
Mass Synaptometry: Applying Mass Cytometry to Single Synapse Analysis. | Gajera CR, Fernandez R, Postupna N, Montine KS, Keene CD, Bendall SC, Montine TJ | Methods in molecular biology (Clifton, N.J.) | 35099792 | Methods Mol Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35099792 |
Modular Antigen-Specific T-cell Biofactories for Calibrated In Vivo Synthesis of Engineered Proteins. | Repellin CE, Patel P, Beviglia L, Javitz H, Sambucetti L, Bhatnagar P | Advanced biosystems | 30984819 | Adv Biosyst | 2018 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30984819 |
Lentivirus Manufacturing Process for Primary T-Cell Biofactory Production. | Radhakrishnan H, Javitz HS, Bhatnagar P | Advanced biosystems | 32390316 | Adv Biosyst | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32390316 |
NK-Cell Biofactory as an Off-the-Shelf Cell-based Vector for Targeted In Situ Synthesis of Engineered Proteins. | Repellin CE, Ssemadaali MA, Newmyer S, Radhakrishnan H, Javitz HS, Bhatnagar P | Advanced biology | 33871182 | Adv Biol (Weinh) | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33871182 |
Cell-Based Platform for Antigen Testing and Its Application for SARS-CoV-2 Infection. | Ssemadaali MA, Newmyer S, Radhakrishnan H, Arredondo J, Javitz HS, Dandekar S, Bhatnagar P | Microbiology spectrum | 35852348 | Microbiol Spectr | 2022 Aug 31 | https://www.ncbi.nlm.nih.gov/pubmed/35852348 |
Electrically regulated cell-based intervention for viral infections. | Newmyer S, Ssemadaali MA, Radhakrishnan H, Javitz HS, Bhatnagar P | Bioengineering & translational medicine | 36925710 | Bioeng Transl Med | 2023 Mar | https://www.ncbi.nlm.nih.gov/pubmed/36925710 |
Primary T-cell-based delivery platform for in vivo synthesis of engineered proteins. | Radhakrishnan H, Newmyer SL, Ssemadaali MA, Javitz HS, Bhatnagar P | Bioengineering & translational medicine | 38193126 | Bioeng Transl Med | 2024 Jan | https://www.ncbi.nlm.nih.gov/pubmed/38193126 |
Genetically engineered pair of cells for serological testing and its application for SARS-CoV-2. | Ssemadaali MA, Arredondo J, Buser EA, Newmyer S, Radhakrishnan H, Javitz HS, Dandekar S, Bhatnagar P | Bioengineering & translational medicine | 37206248 | Bioeng Transl Med | 2023 May | https://www.ncbi.nlm.nih.gov/pubmed/37206248 |
Engineered CD4 T cells for in vivo delivery of therapeutic proteins. | Radhakrishnan H, Newmyer SL, Javitz HS, Bhatnagar P | Proceedings of the National Academy of Sciences of the United States of America | 39312667 | Proc Natl Acad Sci U S A | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/39312667 |
Engineered Ovarian Cancer Cell Lines for Validation of CAR T Cell Function. | Repellin CE, Ganesan P, Alcudia JF, Lakshmireddy HKD, Patel P, Beviglia L, Javitz HS, Sambucetti L, Bhatnagar P | Advanced biosystems | 32293122 | Adv Biosyst | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/32293122 |
Using Communication Theory of Identity to Evaluate Decision Aids: Focus Group Research with African American Prostate Cancer Survivors. | Upshaw SJ | Health communication | 31814430 | Health Commun | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31814430 |
Higher Ultraviolet Radiation Exposure Among Rural-Dwelling Versus Urban-Dwelling Adults and Children: Implications for Skin Cancer Prevention. | Nagelhout ES, Lensink R, Zhu A, Parsons BG, Haaland B, Hashibe M, Grossman D, VanDerslice J, Gren LH, Jensen JD, Wu YP | Journal of community health | 32542551 | J Community Health | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/32542551 |
Temporal frames, temporal focus, and behavioral expectations: The persuasive impact of near and distant threats. | Pokharel M, Jensen JD, Taylor-Burton S, King AJ, John KK, Upshaw S | Social science & medicine (1982) | 37229932 | Soc Sci Med | 2023 Jul | https://www.ncbi.nlm.nih.gov/pubmed/37229932 |
Revisiting nutrition backlash: Psychometric properties and discriminant validity of the nutrition backlash scale. | Jensen JD, Giorgi EA, Jackson JR, Berger J, Katz RA, Mobley AR | Nutrition (Burbank, Los Angeles County, Calif.) | 32871324 | Nutrition | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32871324 |
Validating Cross-Modal Measures for Comparative Research: Message Veracity, Novelty, and Memorability. | Jensen JD, Krakow MM, Christy KR, Ratcliff CL, Pokharel M, Lillie H | Psychology & marketing | 38962756 | Psychol Mark | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/38962756 |
Do 360-Character Wireless Emergency Alert (WEA) Messages Work Better than 90-Character Messages? Testing the Risk Communication Consensus. | Carlson EJ, Bean H, Ratcliff C, Pokharel M, Barbour J | Journal of contingencies and crisis management | 39328310 | J Conting Crisis Manag | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/39328310 |
Emerging applications of eye-tracking technology in dermatology. | John KK, Jensen JD, King AJ, Pokharel M, Grossman D | Journal of dermatological science | 29655589 | J Dermatol Sci | 2018 Apr 6 | https://www.ncbi.nlm.nih.gov/pubmed/29655589 |
Do Pattern-Focused Visuals Improve Skin Self-Examination Performance? Explicating the Visual Skill Acquisition Model. | John KK, Jensen JD, King AJ, Ratcliff CL, Grossman D | Journal of health communication | 28759333 | J Health Commun | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28759333 |
Death Narratives, Negative Emotion, and Counterarguing: Testing Fear, Anger, and Sadness as Mechanisms of Effect. | Lillie HM, Jensen JD, Pokharel M, Upshaw SJ | Journal of health communication | 34569434 | J Health Commun | 2021 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/34569434 |
Are some narratives better than others?: The impact of different narrative forms on adolescents' intentions to text and drive. | Scherr CL, Lillie H, Ratcliff CL, Krakow M, Liu M, Jensen JD | Risk analysis : an official publication of the Society for Risk Analysis | 35104924 | Risk Anal | 2022 Oct | https://www.ncbi.nlm.nih.gov/pubmed/35104924 |
Cancer Information Overload Across Time: Evidence from Two Longitudinal Studies. | Lillie H, Katz RA, Carcioppolo N, Giorgi EA, Jensen JD | Health communication | 35172651 | Health Commun | 2023 Oct | https://www.ncbi.nlm.nih.gov/pubmed/35172651 |
Tailored visuals, implementation interventions, and sun safe behavior: A longitudinal message experiment. | Jensen JD, Parsons BG, Nagelhout ES, Pokharel M, Christy KR, Ratcliff CL, Grossman D, Haaland B, Wu YP | Health psychology : official journal of the Division of Health Psychology, American Psychological Association | 36074598 | Health Psychol | 2023 Jan | https://www.ncbi.nlm.nih.gov/pubmed/36074598 |
Increasing Skin Cancer Prevention in Young Adults: the Cumulative Impact of Personalized UV Photography and MC1R Genetic Testing. | Wu YP, Hamilton JG, Kaphingst KA, Jensen JD, Kohlmann W, Parsons BG, Lillie HM, Wang X, Haaland B, Wankier AP, Grossman D, Hay JL | Journal of cancer education : the official journal of the American Association for Cancer Education | 36306029 | J Cancer Educ | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/36306029 |
Healthcare Providers' Resilience Communication: A New Type of Patient-Centered Communication. | Lillie HM | Journal of health communication | 38982683 | J Health Commun | 2024 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/38982683 |
'I had a bigger cancer risk than I thought…': The experience of receiving personalized risk information as part of a skin cancer prevention intervention in the college setting. | Brady HL, Hamilton JG, Kaphingst KA, Jensen JD, Kohlmann W, Parsons BG, Lillie HM, Wankier AP, Smith HJ, Grossman D, Hay JL, Wu YP | Health expectations : an international journal of public participation in health care and health policy | 36225123 | Health Expect | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36225123 |
Developing skin cancer education materials for darker skin populations: crowdsourced design, message targeting, and acral lentiginous melanoma. | Upshaw SJ, Jensen JD, Giorgi EA, Pokharel M, Lillie HM, Adams DR, John KK, Wu YP, Grossman D | Journal of behavioral medicine | 36125669 | J Behav Med | 2023 Jun | https://www.ncbi.nlm.nih.gov/pubmed/36125669 |
Visual Tailoring and Skin Cancer Prevention: Comparing Personalized, Stock, and Non-Ultraviolet Images. | Pokharel M, Jensen JD, John KK, Christy KR, Taylor-Burton S, Upshaw S | Health communication | 35765121 | Health Commun | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/35765121 |
The Impact of Social and Material Resources on Resilience Communication at the Intersection of Race and Gender. | Lillie HM, Sánchez Sánchez V | Journal of health communication | 36484127 | J Health Commun | 2022 Oct 3 | https://www.ncbi.nlm.nih.gov/pubmed/36484127 |
The Feasibility and Acceptability of Using a Wearable UV Radiation Exposure Monitoring Device in Adults and Children: Cross-Sectional Questionnaire Study. | Nagelhout ES, Lensink R, Zhu A, Parsons BG, Jensen JD, Wu YP | JMIR dermatology | 33043275 | JMIR Dermatol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33043275 |
Theorizing Foreshadowed Death Narratives: Examining the Impact of Character Death on Narrative Processing and Skin Self-Exam Intentions. | Jensen JD, Yale RN, Krakow M, John KK, King AJ | Journal of health communication | 28060585 | J Health Commun | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/28060585 |
Does it matter if a story character lives or dies?: a message experiment comparing survivor and death narratives. | Lillie HM, Pokharel M, John KK, Christy KR, Upshaw S, Giorgi EA, Jensen JD | Psychology & health | 33464969 | Psychol Health | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33464969 |
Differences in reported sun protection practices, skin cancer knowledge, and perceived risk for skin cancer between rural and urban high school students. | Nagelhout ES, Parsons BG, Haaland B, Tercyak KP, Zaugg K, Zhu A, Harding G, Yancey J, Jensen JD, Grossman D, Wetter DW, Wu YP | Cancer causes & control : CCC | 31522321 | Cancer Causes Control | 2019 Nov | https://www.ncbi.nlm.nih.gov/pubmed/31522321 |
Cancer information overload: Discriminant validity and relationship to sun safe behaviors. | Jensen JD, Pokharel M, Carcioppolo N, Upshaw S, John KK, Katz RA | Patient education and counseling | 31522897 | Patient Educ Couns | 2020 Feb | https://www.ncbi.nlm.nih.gov/pubmed/31522897 |
Political Party Collective Norms, Perceived Norms, and Mask Wearing Behavior: A Test of the Theory of Normative Social Behavior. | Pokharel M, Lillie HM, Jensen JD, King AJ, Ratcliff CL, Barbour JB | Health communication | 38281912 | Health Commun | 2024 Nov | https://www.ncbi.nlm.nih.gov/pubmed/38281912 |
People Wear Masks when they Ski: Comparing Congruent and Incongruent Behavioral Context Appeals. | Liao Y, Adams DR, Lillie HM, Jensen JD | Journal of health communication | 37768095 | J Health Commun | 2023 Nov 2 | https://www.ncbi.nlm.nih.gov/pubmed/37768095 |
Do ultraviolet photos increase sun safe behavior expectations via fear? A randomized controlled trial in a sample of U.S. adults. | Pokharel M, Christy KR, Jensen JD, Giorgi EA, John KK, Wu YP | Journal of behavioral medicine | 30523504 | J Behav Med | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/30523504 |
A four-group experiment to improve Western high school students' sun protection behaviors. | Wu YP, Parsons BG, Nagelhout E, Haaland B, Jensen J, Zaugg K, Caputo H, Lensink R, Harding G, Yancey J, Klein SZ, Leachman SA, Tercyak KP | Translational behavioral medicine | 31094440 | Transl Behav Med | 2019 May 16 | https://www.ncbi.nlm.nih.gov/pubmed/31094440 |
Obstacles to skin self-examination: are frontier adults inclined abstainers? | Jensen JD, Pokharel M, King AJ, John KK, Wu YP, Grossman D | Psychology, health & medicine | 31847571 | Psychol Health Med | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31847571 |
Is News Surveillance related to Cancer Knowledge in Underserved Adults? Testing Three Versions of the Cognitive Mediation Model. | Jensen JD, King AJ, Torres DP, Krakow M, Coe K, Upshaw S | Journalism studies | 33100901 | Journal Stud | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33100901 |
Spit, Disgust, and Parasite Stress Theory: A Message Experiment. | Chavez-Yenter D, Lille HM, Gorissen S, John KK, Vega AS, Jensen JD | Journal of health communication | 37382498 | J Health Commun | 2023 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/37382498 |
Using narratives to correct politically charged health misinformation and address affective belief echoes. | Lillie HM, Ratcliff CL, King AJ, Pokharel M, Jensen JD | Journal of public health (Oxford, England) | 38632889 | J Public Health (Oxf) | 2024 Aug 25 | https://www.ncbi.nlm.nih.gov/pubmed/38632889 |
Resilience Communication Mitigates the Negative Relational Effects of Topic Avoidance: Evidence from Parental Caregiving and COVID-19 Pandemic Contexts. | Lillie HM, Venetis MK, Chernichky-Karcher S | Personal Relationships | 38737382 | Pers Relatsh | 2023 Dec | https://www.ncbi.nlm.nih.gov/pubmed/38737382 |
Reactivity to UV Radiation Exposure Monitoring Using Personal Exposure Devices for Skin Cancer Prevention: Longitudinal Observational Study. | Parsons BG, Nagelhout ES, Wankier AP, Hu N, Lensink R, Zhu A, Nottingham K, Grossman D, Jensen JD, Wu YP | JMIR mHealth and uHealth | 34581683 | JMIR Mhealth Uhealth | 2021 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/34581683 |
Communicating scientific uncertainty in the early stages of the COVID-19 pandemic: A message experiment. | Adams DR, Ratcliff CL, Pokharel M, Jensen JD, Liao Y | Risk analysis : an official publication of the Society for Risk Analysis | 37963681 | Risk Anal | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/37963681 |
A Missing Mechanism of Effect: How People Who Habitually Replot Stories React Differently (Or Not so Differently) to Melanoma Narratives. | Lillie HM, Pokharel M, Jensen JD | Journal of health communication | 39550610 | J Health Commun | 2025 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/39550610 |
Compact and adjustable compensator for AOD spatial and temporal dispersion using off-the-shelf components. | Yamaguchi A, Karagyozov D, Gershow MH | Optics letters | 33793507 | Opt Lett | 2021 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/33793507 |
Direction Selectivity in Drosophila Proprioceptors Requires the Mechanosensory Channel Tmc. | He L, Gulyanon S, Mihovilovic Skanata M, Karagyozov D, Heckscher ES, Krieg M, Tsechpenakis G, Gershow M, Tracey WD Jr | Current biology : CB | 30853433 | Curr Biol | 2019 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/30853433 |
Switch-like and persistent memory formation in individual Drosophila larvae. | Lesar A, Tahir J, Wolk J, Gershow M | eLife | 34636720 | Elife | 2021 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/34636720 |
Recording Neural Activity in Unrestrained Animals with Three-Dimensional Tracking Two-Photon Microscopy. | Karagyozov D, Mihovilovic Skanata M, Lesar A, Gershow M | Cell reports | 30380425 | Cell Rep | 2018 Oct 30 | https://www.ncbi.nlm.nih.gov/pubmed/30380425 |
Neural Substrates of Drosophila Larval Anemotaxis. | Jovanic T, Winding M, Cardona A, Truman JW, Gershow M, Zlatic M | Current biology : CB | 30744969 | Curr Biol | 2019 Feb 18 | https://www.ncbi.nlm.nih.gov/pubmed/30744969 |
Variance adaptation in navigational decision making. | Gepner R, Wolk J, Wadekar DS, Dvali S, Gershow M | eLife | 30480547 | Elife | 2018 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/30480547 |
Dedicated photoreceptor pathways in Drosophila larvae mediate navigation by processing either spatial or temporal cues. | Humberg TH, Bruegger P, Afonso B, Zlatic M, Truman JW, Gershow M, Samuel A, Sprecher SG | Nature communications | 29593252 | Nat Commun | 2018 Mar 28 | https://www.ncbi.nlm.nih.gov/pubmed/29593252 |
Multi-neuronal recording in unrestrained animals with all acousto-optic random-access line-scanning two-photon microscopy. | Yamaguchi A, Wu R, McNulty P, Karagyozov D, Mihovilovic Skanata M, Gershow M | Frontiers in neuroscience | 37389365 | Front Neurosci | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37389365 |
CRASH2p: Closed-loop Two Photon Imaging in a Freely Moving Animal. | McNulty P, Wu R, Yamaguchi A, Heckscher ES, Haas A, Nwankpa A, Skanata MM, Gershow M | bioRxiv : the preprint server for biology | 38826435 | bioRxiv | 2024 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/38826435 |
Role of indentation depth and contact area on human perception of softness for haptic interfaces. | Dhong C, Miller R, Root NB, Gupta S, Kayser LV, Carpenter CW, Loh KJ, Ramachandran VS, Lipomi DJ | Science advances | 31497646 | Sci Adv | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31497646 |
Effects of flexibility and branching of side chains on the mechanical properties of low-bandgap conjugated polymers. | Sugiyama F, Kleinschmidt AT, Kayser LV, Rodriquez D, Finn M 3rd, Alkhadra MA, Wan JM, Ramírez J, Chiang AS, Root SE, Savagatrup S, Lipomi DJ | Polymer chemistry | 30873221 | Polym Chem | 2018 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/30873221 |
Metallic Nanoislands on Graphene for Biomechanical Sensing. | Ramírez J, Polat B, Lipomi DJ | ACS omega | 32656394 | ACS Omega | 2020 Jul 7 | https://www.ncbi.nlm.nih.gov/pubmed/32656394 |
Role of fingerprint-inspired relief structures in elastomeric slabs for detecting frictional differences arising from surface monolayers. | Dhong C , Kayser LV , Arroyo R , Shin A , Finn M , Kleinschmidt AT , Lipomi DJ | Soft matter | 30152497 | Soft Matter | 2018 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/30152497 |
Electropneumotactile Stimulation: Multimodal Haptic Actuators Enabled by a Stretchable Conductive Polymer on Inflatable Pockets. | Carpenter CW, Malinao MG, Rafeedi TA, Rodriquez D, Melissa Tan ST, Root NB, Skelil K, Ramírez J, Polat B, Root SE, Ramachandran VS, Lipomi DJ | Advanced materials technologies | 32905479 | Adv Mater Technol | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32905479 |
Single-Nanowire Strain Sensors Fabricated by Nanoskiving. | Jibril L, Ramírez J, Zaretski AV, Lipomi DJ | Sensors and actuators. A, Physical | 28860679 | Sens Actuators A Phys | 2017 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/28860679 |
RAFT Polymerization of an Intrinsically Stretchable Water-Soluble Block Copolymer Scaffold for PEDOT. | Kayser LV, Russell MD, Rodriquez D, Abuhamdieh SN, Dhong C, Khan S, Stein AN, Ramírez J, Lipomi DJ | Chemistry of materials : a publication of the American Chemical Society | 30930534 | Chem Mater | 2018 Jul 10 | https://www.ncbi.nlm.nih.gov/pubmed/30930534 |
Stretchable Conductive Polymers and Composites Based on PEDOT and PEDOT:PSS. | Kayser LV, Lipomi DJ | Advanced materials (Deerfield Beach, Fla.) | 30600559 | Adv Mater | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30600559 |
Metallic nanoislands on graphene: A metamaterial for chemical, mechanical, optical, and biological applications. | Marin BC, Ramirez J, Root SE, Aklile E, Lipomi DJ | Nanoscale horizons | 29276626 | Nanoscale Horiz | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/29276626 |
Metallic Nanoislands on Graphene for Monitoring Swallowing Activity in Head and Neck Cancer Patients. | Ramírez J, Rodriquez D, Qiao F, Warchall J, Rye J, Aklile E, S-C Chiang A, Marin BC, Mercier PP, Cheng CK, Hutcheson KA, Shinn EH, Lipomi DJ | ACS nano | 29874030 | ACS Nano | 2018 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/29874030 |
Exploring the limits of sensitivity for strain gauges of graphene and hexagonal boron nitride decorated with metallic nanoislands. | Ramírez J, Urbina AD, Kleinschmidt AT, Finn M 3rd, Edmunds SJ, Esparza GL, Lipomi DJ | Nanoscale | 32409812 | Nanoscale | 2020 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/32409812 |
Graphene-Metal Composite Sensors with Near-Zero Temperature Coefficient of Resistance. | Marin BC, Root SE, Urbina AD, Aklile E, Miller R, Zaretski AV, Lipomi DJ | ACS omega | 28261691 | ACS Omega | 2017 Feb 28 | https://www.ncbi.nlm.nih.gov/pubmed/28261691 |
Combining High Sensitivity and Dynamic Range: Wearable Thin-Film Composite Strain Sensors of Graphene, Ultrathin Palladium, and PEDOT:PSS. | Ramírez J, Rodriquez D, Urbina A, Cardenas A, Lipomi DJ | ACS applied nano materials | 33829151 | ACS Appl Nano Mater | 2019 Apr 26 | https://www.ncbi.nlm.nih.gov/pubmed/33829151 |
The Language of Glove: Wireless gesture decoder with low-power and stretchable hybrid electronics. | O'Connor TF, Fach ME, Miller R, Root SE, Mercier PP, Lipomi DJ | PloS one | 28700603 | PLoS One | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28700603 |
Stretchable and Degradable Semiconducting Block Copolymers. | Sugiyama F, Kleinschmidt AT, Kayser LV, Alkhadra MA, Wan JM, Chiang AS, Rodriquez D, Root SE, Savagatrup S, Lipomi DJ | Macromolecules | 30930487 | Macromolecules | 2018 Aug 14 | https://www.ncbi.nlm.nih.gov/pubmed/30930487 |
SERS-enhanced piezoplasmonic graphene composite for biological and structural strain mapping. | Marin BC, Liu J, Aklile E, Urbina AD, Chiang AS, Lawrence N, Chen S, Lipomi DJ | Nanoscale | 28055038 | Nanoscale | 2017 Jan 19 | https://www.ncbi.nlm.nih.gov/pubmed/28055038 |
Ionotactile Stimulation: Nonvolatile Ionic Gels for Human-Machine Interfaces. | Root SE, Carpenter CW, Kayser LV, Rodriquez D, Davies DM, Wang S, Tan STM, Meng YS, Lipomi DJ | ACS omega | 29399651 | ACS Omega | 2018 Jan 31 | https://www.ncbi.nlm.nih.gov/pubmed/29399651 |
Healable Thermoplastic for Kinesthetic Feedback in Wearable Haptic Devices. | Carpenter CW, Ting Melissa Tan S, Keef C, Skelil K, Malinao M, Rodriquez D, Alkhadra MA, Ramírez J, Lipomi DJ | Sensors and actuators. A, Physical | 31777429 | Sens Actuators A Phys | 2019 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/31777429 |
Stretchable Conjugated Polymers: A Case Study in Topic Selection for New Research Groups. | Kleinschmidt AT, Lipomi DJ | Accounts of chemical research | 30516970 | Acc Chem Res | 2018 Dec 18 | https://www.ncbi.nlm.nih.gov/pubmed/30516970 |
Virtual Texture Generated using Elastomeric Conductive Block Copolymer in Wireless Multimodal Haptic Glove. | Keef CV, Kayser LV, Tronboll S, Carpenter CW, Root NB, Finn M 3rd, O'Connor TF, Abuhamdieh SN, Davies DM, Runser R, Meng YS, Ramachandran VS, Lipomi DJ | Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) | 32656536 | Adv Intell Syst | 2020 Apr | https://www.ncbi.nlm.nih.gov/pubmed/32656536 |
Organic Haptics: Intersection of Materials Chemistry and Tactile Perception. | Lipomi DJ, Dhong C, Carpenter CW, Root NB, Ramachandran VS | Advanced functional materials | 34276273 | Adv Funct Mater | 2020 Jul 16 | https://www.ncbi.nlm.nih.gov/pubmed/34276273 |
Polymer Chemistry for Haptics, Soft Robotics, and Human-Machine Interfaces. | Schara S, Blau R, Church DC, Pokorski JK, Lipomi DJ | Advanced functional materials | 34924911 | Adv Funct Mater | 2021 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/34924911 |
Therapeutic hypothermia reduces cortical inflammation associated with utah array implants. | Dugan EA, Bennett C, Tamames I, Dietrich WD, King CS, Prasad A, Rajguru SM | Journal of neural engineering | 32240985 | J Neural Eng | 2020 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/32240985 |
Common marmoset (Callithrix jacchus) as a primate model for behavioral neuroscience studies. | Prins NW, Pohlmeyer EA, Debnath S, Mylavarapu R, Geng S, Sanchez JC, Rothen D, Prasad A | Journal of neuroscience methods | 28400103 | J Neurosci Methods | 2017 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/28400103 |
Spinal cord neural interfacing in common marmosets (Callithrix jacchus). | Prins NW, Mylavarapu R, Shoup AM, Debnath S, Prasad A | Journal of neural engineering | 31480029 | J Neural Eng | 2020 Jan 14 | https://www.ncbi.nlm.nih.gov/pubmed/31480029 |
Chronic recordings from the marmoset motor cortex reveals modulation of neural firing and local field potentials overlap with macaques. | Mylavarapu R, Prins NW, Pohlmeyer EA, Shoup AM, Debnath S, Geng S, Sanchez JC, Schwartz O, Prasad A | Journal of neural engineering | 34225263 | J Neural Eng | 2021 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/34225263 |
The complement cascade at the Utah microelectrode-tissue interface. | Bennett C, Álvarez-Ciara A, Franklin M, Dietrich WD, Prasad A | Biomaterials | 33310540 | Biomaterials | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33310540 |
Long-term stability of neural signals from microwire arrays implanted in common marmoset motor cortex and striatum. | Debnath S, Prins NW, Pohlmeyer E, Mylavarapu R, Geng S, Sanchez JC, Prasad A | Biomedical physics & engineering express | 31011432 | Biomed Phys Eng Express | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31011432 |
Neuroinflammation, oxidative stress, and blood-brain barrier (BBB) disruption in acute Utah electrode array implants and the effect of deferoxamine as an iron chelator on acute foreign body response. | Bennett C, Mohammed F, Álvarez-Ciara A, Nguyen MA, Dietrich WD, Rajguru SM, Streit WJ, Prasad A | Biomaterials | 30343257 | Biomaterials | 2019 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30343257 |
Blood brain barrier (BBB)-disruption in intracortical silicon microelectrode implants. | Bennett C, Samikkannu M, Mohammed F, Dietrich WD, Rajguru SM, Prasad A | Biomaterials | 29477707 | Biomaterials | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/29477707 |
Biologically Inspired Smart Release System Based on 3D Bioprinted Perfused Scaffold for Vascularized Tissue Regeneration. | Cui H, Zhu W, Holmes B, Zhang LG | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 27818910 | Adv Sci (Weinh) | 2016 Aug | https://www.ncbi.nlm.nih.gov/pubmed/27818910 |
Engineering a Novel 3D Printed Vascularized Tissue Model for Investigating Breast Cancer Metastasis to Bone. | Cui H, Esworthy T, Zhou X, Hann SY, Glazer RI, Li R, Zhang LG | Advanced healthcare materials | 31846231 | Adv Healthc Mater | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31846231 |
Recent advances in 3D printing: vascular network for tissue and organ regeneration. | Hann SY, Cui H, Esworthy T, Miao S, Zhou X, Lee SJ, Fisher JP, Zhang LG | Translational research : the journal of laboratory and clinical medicine | 31004563 | Transl Res | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31004563 |
4D printing smart biomedical scaffolds with novel soybean oil epoxidized acrylate. | Miao S, Zhu W, Castro NJ, Nowicki M, Zhou X, Cui H, Fisher JP, Zhang LG | Scientific reports | 27251982 | Sci Rep | 2016 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/27251982 |
Hierarchical Fabrication of Engineered Vascularized Bone Biphasic Constructs via Dual 3D Bioprinting: Integrating Regional Bioactive Factors into Architectural Design. | Cui H, Zhu W, Nowicki M, Zhou X, Khademhosseini A, Zhang LG | Advanced healthcare materials | 27383032 | Adv Healthc Mater | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27383032 |
A 3D printed nano bone matrix for characterization of breast cancer cell and osteoblast interactions. | Zhu W, Castro NJ, Cui H, Zhou X, Boualam B, McGrane R, Glazer RI, Zhang LG | Nanotechnology | 27346678 | Nanotechnology | 2016 Aug 5 | https://www.ncbi.nlm.nih.gov/pubmed/27346678 |
Four-Dimensional Printing Hierarchy Scaffolds with Highly Biocompatible Smart Polymers for Tissue Engineering Applications. | Miao S, Zhu W, Castro NJ, Leng J, Zhang LG | Tissue engineering. Part C, Methods | 28195832 | Tissue Eng Part C Methods | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/28195832 |
4D printing of polymeric materials for tissue and organ regeneration. | Miao S, Castro N, Nowicki M, Xia L, Cui H, Zhou X, Zhu W, Lee SJ, Sarkar K, Vozzi G, Tabata Y, Fisher J, Zhang LG | Materials today (Kidlington, England) | 29403328 | Mater Today (Kidlington) | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29403328 |
Cold Atmospheric Plasma Modified Electrospun Scaffolds with Embedded Microspheres for Improved Cartilage Regeneration. | Zhu W, Castro NJ, Cheng X, Keidar M, Zhang LG | PloS one | 26222527 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26222527 |
Design of a Novel 3D Printed Bioactive Nanocomposite Scaffold for Improved Osteochondral Regeneration. | Castro NJ, Patel R, Zhang LG | Cellular and molecular bioengineering | 26366231 | Cell Mol Bioeng | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26366231 |
In vitro and in vivo evaluation of 3D bioprinted small-diameter vasculature with smooth muscle and endothelium. | Cui H, Zhu W, Huang Y, Liu C, Yu ZX, Nowicki M, Miao S, Cheng Y, Zhou X, Lee SJ, Zhou Y, Wang S, Mohiuddin M, Horvath K, Zhang LG | Biofabrication | 31470437 | Biofabrication | 2019 Oct 21 | https://www.ncbi.nlm.nih.gov/pubmed/31470437 |
4D physiologically adaptable cardiac patch: A 4-month in vivo study for the treatment of myocardial infarction. | Cui H, Liu C, Esworthy T, Huang Y, Yu ZX, Zhou X, San H, Lee SJ, Hann SY, Boehm M, Mohiuddin M, Fisher JP, Zhang LG | Science advances | 32637623 | Sci Adv | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32637623 |
A novel near-infrared light responsive 4D printed nanoarchitecture with dynamically and remotely controllable transformation. | Cui H, Miao S, Esworthy T, Lee SJ, Zhou X, Hann SY, Webster TJ, Harris BT, Zhang LG | Nano research | 33312444 | Nano Res | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/33312444 |
Integrating biologically inspired nanomaterials and table-top stereolithography for 3D printed biomimetic osteochondral scaffolds. | Castro NJ, O'Brien J, Zhang LG | Nanoscale | 26234364 | Nanoscale | 2015 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/26234364 |
Stereolithographic 4D Bioprinting of Multiresponsive Architectures for Neural Engineering. | Miao S, Cui H, Nowicki M, Xia L, Zhou X, Lee SJ, Zhu W, Sarkar K, Zhang Z, Zhang LG | Advanced biosystems | 30906853 | Adv Biosyst | 2018 Sep | https://www.ncbi.nlm.nih.gov/pubmed/30906853 |
A synergistic approach to the design, fabrication and evaluation of 3D printed micro and nano featured scaffolds for vascularized bone tissue repair. | Holmes B, Bulusu K, Plesniak M, Zhang LG | Nanotechnology | 26758780 | Nanotechnology | 2016 Feb 12 | https://www.ncbi.nlm.nih.gov/pubmed/26758780 |
How can 3D printing be a powerful tool in nanomedicine? | Zhu W, Webster TJ, Zhang LG | Nanomedicine (London, England) | 29338559 | Nanomedicine (Lond) | 2018 Feb | https://www.ncbi.nlm.nih.gov/pubmed/29338559 |
Integration of biological systems with electronic-mechanical assemblies. | Yi N, Cui H, Zhang LG, Cheng H | Acta biomaterialia | 31004844 | Acta Biomater | 2019 Sep 1 | https://www.ncbi.nlm.nih.gov/pubmed/31004844 |
Enhanced bone tissue regeneration using a 3D printed microstructure incorporated with a hybrid nano hydrogel. | Heo DN, Castro NJ, Lee SJ, Noh H, Zhu W, Zhang LG | Nanoscale | 28211933 | Nanoscale | 2017 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/28211933 |
3D Bioprinting for Organ Regeneration. | Cui H, Nowicki M, Fisher JP, Zhang LG | Advanced healthcare materials | 27995751 | Adv Healthc Mater | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27995751 |
Simulated Body Fluid Nucleation of Three-Dimensional Printed Elastomeric Scaffolds for Enhanced Osteogenesis. | Castro NJ, Tan WN, Shen C, Zhang LG | Tissue engineering. Part A | 27298115 | Tissue Eng Part A | 2016 Jul | https://www.ncbi.nlm.nih.gov/pubmed/27298115 |
Photolithographic-stereolithographic-tandem fabrication of 4D smart scaffolds for improved stem cell cardiomyogenic differentiation. | Miao S, Cui H, Nowicki M, Lee SJ, Almeida J, Zhou X, Zhu W, Yao X, Masood F, Plesniak MW, Mohiuddin M, Zhang LG | Biofabrication | 29651999 | Biofabrication | 2018 May 2 | https://www.ncbi.nlm.nih.gov/pubmed/29651999 |
Bio-Based Polymers for 3D Printing of Bioscaffolds. | Yang E, Miao S, Zhong J, Zhang Z, Mills DK, Zhang LG | Polymer reviews (Philadelphia, Pa.) | 30911289 | Polym Rev (Phila Pa) | 2018 | https://www.ncbi.nlm.nih.gov/pubmed/30911289 |
Integrating three-dimensional printing and nanotechnology for musculoskeletal regeneration. | Nowicki M, Castro NJ, Rao R, Plesniak M, Zhang LG | Nanotechnology | 28762957 | Nanotechnology | 2017 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/28762957 |
4D anisotropic skeletal muscle tissue constructs fabricated by staircase effect strategy. | Miao S, Nowicki M, Cui H, Lee SJ, Zhou X, Mills DK, Zhang LG | Biofabrication | 31026857 | Biofabrication | 2019 Jun 24 | https://www.ncbi.nlm.nih.gov/pubmed/31026857 |
3D bioprinting for cardiovascular regeneration and pharmacology. | Cui H, Miao S, Esworthy T, Zhou X, Lee SJ, Liu C, Yu ZX, Fisher JP, Mohiuddin M, Zhang LG | Advanced drug delivery reviews | 30053441 | Adv Drug Deliv Rev | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/30053441 |
Advanced 4D Bioprinting Technologies for Brain Tissue Modeling and Study. | Esworthy TJ, Miao S, Lee SJ, Zhou X, Cui H, Zuo YY, Zhang LG | International journal of smart and nano materials | 32864037 | Int J Smart Nano Mater | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/32864037 |
3D Printed Stretchable Tactile Sensors. | Guo SZ, Qiu K, Meng F, Park SH, McAlpine MC | Advanced materials (Deerfield Beach, Fla.) | 28474793 | Adv Mater | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28474793 |
3D Printed Electrically-Driven Soft Actuators. | Haghiashtiani G, Habtour E, Park SH, Gardea F, McAlpine MC | Extreme Mechanics Letters | 32596434 | Extreme Mech Lett | 2018 May | https://www.ncbi.nlm.nih.gov/pubmed/32596434 |
3D printed deformable sensors. | Zhu Z, Park HS, McAlpine MC | Science advances | 32596461 | Sci Adv | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32596461 |
The Role of Nanoparticle Design in Determining Analytical Performance of Lateral Flow Immunoassays. | Zhan L, Guo SZ, Song F, Gong Y, Xu F, Boulware DR, McAlpine MC, Chan WCW, Bischof JC | Nano letters | 29120648 | Nano Lett | 2017 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/29120648 |
3D Printed Functional and Biological Materials on Moving Freeform Surfaces. | Zhu Z, Guo SZ, Hirdler T, Eide C, Fan X, Tolar J, McAlpine MC | Advanced materials (Deerfield Beach, Fla.) | 29691902 | Adv Mater | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29691902 |
3D Printed Bionic Nanodevices. | Kong YL, Gupta MK, Johnson BN, McAlpine MC | Nano today | 27617026 | Nano Today | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27617026 |
3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments. | Meng F, Meyer CM, Joung D, Vallera DA, McAlpine MC, Panoskaltsis-Mortari A | Advanced materials (Deerfield Beach, Fla.) | 30663123 | Adv Mater | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/30663123 |
3D Printed Programmable Release Capsules. | Gupta MK, Meng F, Johnson BN, Kong YL, Tian L, Yeh YW, Masters N, Singamaneni S, McAlpine MC | Nano letters | 26042472 | Nano Lett | 2015 Aug 12 | https://www.ncbi.nlm.nih.gov/pubmed/26042472 |
3D printed self-supporting elastomeric structures for multifunctional microfluidics. | Su R, Wen J, Su Q, Wiederoder MS, Koester SJ, Uzarski JR, McAlpine MC | Science advances | 33036980 | Sci Adv | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33036980 |
3D Printed Neural Regeneration Devices. | Joung D, Lavoie NS, Guo SZ, Park SH, Parr AM, McAlpine MC | Advanced functional materials | 32038121 | Adv Funct Mater | 2020 Jan 3 | https://www.ncbi.nlm.nih.gov/pubmed/32038121 |
In Situ Expansion, Differentiation, and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid. | Kupfer ME, Lin WH, Ravikumar V, Qiu K, Wang L, Gao L, Bhuiyan DB, Lenz M, Ai J, Mahutga RR, Townsend D, Zhang J, McAlpine MC, Tolkacheva EG, Ogle BM | Circulation research | 32228120 | Circ Res | 2020 Jul 3 | https://www.ncbi.nlm.nih.gov/pubmed/32228120 |
3D Printed Polymer Photodetectors. | Park SH, Su R, Jeong J, Guo SZ, Qiu K, Joung D, Meng F, McAlpine MC | Advanced materials (Deerfield Beach, Fla.) | 30151842 | Adv Mater | 2018 Aug 28 | https://www.ncbi.nlm.nih.gov/pubmed/30151842 |
3D Printed Organ Models with Physical Properties of Tissue and Integrated Sensors. | Qiu K, Zhao Z, Haghiashtiani G, Guo SZ, He M, Su R, Zhu Z, Bhuiyan DB, Murugan P, Meng F, Park SH, Chu CC, Ogle BM, Saltzman DA, Konety BR, Sweet RM, McAlpine MC | Advanced materials technologies | 29608202 | Adv Mater Technol | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29608202 |
3D Printed Stem-Cell Derived Neural Progenitors Generate Spinal Cord Scaffolds. | Joung D, Truong V, Neitzke CC, Guo SZ, Walsh PJ, Monat JR, Meng F, Park SH, Dutton JR, Parr AM, McAlpine MC | Advanced functional materials | 32595422 | Adv Funct Mater | 2018 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/32595422 |
3D Printed Organ Models for Surgical Applications. | Qiu K, Haghiashtiani G, McAlpine MC | Annual review of analytical chemistry (Palo Alto, Calif.) | 29589961 | Annu Rev Anal Chem (Palo Alto Calif) | 2018 Jun 12 | https://www.ncbi.nlm.nih.gov/pubmed/29589961 |
Corrigendum to "3D printed bionic nanodevices" [Nano Today 11 (2016) 330-350]. | Kong YL, Gupta MK, Johnson BN, McAlpine MC | Nano today | 31186673 | Nano Today | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31186673 |
3D printed patient-specific aortic root models with internal sensors for minimally invasive applications. | Haghiashtiani G, Qiu K, Zhingre Sanchez JD, Fuenning ZJ, Nair P, Ahlberg SE, Iaizzo PA, McAlpine MC | Science advances | 32923641 | Sci Adv | 2020 Aug | https://www.ncbi.nlm.nih.gov/pubmed/32923641 |
3D Printed Skin-Interfaced UV-Visible Hybrid Photodetectors. | Ouyang X, Su R, Ng DWH, Han G, Pearson DR, McAlpine MC | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 35818683 | Adv Sci (Weinh) | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/35818683 |
3D-printed flexible organic light-emitting diode displays. | Su R, Park SH, Ouyang X, Ahn SI, McAlpine MC | Science advances | 34995118 | Sci Adv | 2022 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/34995118 |
Conduction Cooling and Plasmonic Heating Dramatically Increase Droplet Vitrification Volumes for Cell Cryopreservation. | Zhan L, Guo SZ, Kangas J, Shao Q, Shiao M, Khosla K, Low WC, McAlpine MC, Bischof J | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 34141523 | Adv Sci (Weinh) | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/34141523 |
The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits. | Gardner BM, Chowdhury S, Lander GC, Martin A | Journal of molecular biology | 25659908 | J Mol Biol | 2015 Mar 27 | https://www.ncbi.nlm.nih.gov/pubmed/25659908 |
Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease. | Puchades C, Ding B, Song A, Wiseman RL, Lander GC, Glynn SE | Molecular cell | 31327635 | Mol Cell | 2019 Sep 5 | https://www.ncbi.nlm.nih.gov/pubmed/31327635 |
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing. | Fribourgh JL, Srivastava A, Sandate CR, Michael AK, Hsu PL, Rakers C, Nguyen LT, Torgrimson MR, Parico GCG, Tripathi S, Zheng N, Lander GC, Hirota T, Tama F, Partch CL | eLife | 32101164 | Elife | 2020 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/32101164 |
An allosteric network in spastin couples multiple activities required for microtubule severing. | Sandate CR, Szyk A, Zehr EA, Lander GC, Roll-Mecak A | Nature structural & molecular biology | 31285604 | Nat Struct Mol Biol | 2019 Aug | https://www.ncbi.nlm.nih.gov/pubmed/31285604 |
Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3. | Hirschi M, Herzik MA Jr, Wie J, Suo Y, Borschel WF, Ren D, Lander GC, Lee SY | Nature | 29019979 | Nature | 2017 Oct 19 | https://www.ncbi.nlm.nih.gov/pubmed/29019979 |
Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases. | Garnham CP, Vemu A, Wilson-Kubalek EM, Yu I, Szyk A, Lander GC, Milligan RA, Roll-Mecak A | Cell | 25959773 | Cell | 2015 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/25959773 |
Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition. | Dambacher CM, Worden EJ, Herzik MA, Martin A, Lander GC | eLife | 26744777 | Elife | 2016 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/26744777 |
Site-specific labeling of proteins for electron microscopy. | Dambacher CM, Lander GC | Journal of structural biology | 26409249 | J Struct Biol | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26409249 |
Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome. | Bashore C, Dambacher CM, Goodall EA, Matyskiela ME, Lander GC, Martin A | Nature structural & molecular biology | 26301997 | Nat Struct Mol Biol | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26301997 |
A guided approach for subtomogram averaging of challenging macromolecular assemblies. | Basanta B, Chowdhury S, Lander GC, Grotjahn DA | Journal of structural biology: X | 33319208 | J Struct Biol X | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/33319208 |
The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading. | Gardner BM, Castanzo DT, Chowdhury S, Stjepanovic G, Stefely MS, Hurley JH, Lander GC, Martin A | Nature communications | 29321502 | Nat Commun | 2018 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/29321502 |
The rod-shaped ATG2A-WIPI4 complex tethers membranes in vitro. | Otomo T, Chowdhury S, Lander GC | Contact (Thousand Oaks (Ventura County, Calif.)) | 30766969 | Contact (Thousand Oaks) | 2018 Jan-Dec | https://www.ncbi.nlm.nih.gov/pubmed/30766969 |
A Multi-model Approach to Assessing Local and Global Cryo-EM Map Quality. | Herzik MA Jr, Fraser JS, Lander GC | Structure (London, England : 1993) | 30449687 | Structure | 2019 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/30449687 |
Substrate-engaged 26S proteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. | de la Peña AH, Goodall EA, Gates SN, Lander GC, Martin A | Science (New York, N.Y.) | 30309908 | Science | 2018 Nov 30 | https://www.ncbi.nlm.nih.gov/pubmed/30309908 |
Setting the dynein motor in motion: New insights from electron tomography. | Grotjahn DA, Lander GC | The Journal of biological chemistry | 31285262 | J Biol Chem | 2019 Sep 6 | https://www.ncbi.nlm.nih.gov/pubmed/31285262 |
Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex. | Chowdhury S, Otomo C, Leitner A, Ohashi K, Aebersold R, Lander GC, Otomo T | Proceedings of the National Academy of Sciences of the United States of America | 30185561 | Proc Natl Acad Sci U S A | 2018 Oct 16 | https://www.ncbi.nlm.nih.gov/pubmed/30185561 |
AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex. | Hirschi M, Lu WT, Santiago-Frangos A, Wilkinson R, Golden SM, Davidson AR, Lander GC, Wiedenheft B | Nature communications | 32483187 | Nat Commun | 2020 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/32483187 |
Structural organization of the dynein-dynactin complex bound to microtubules. | Chowdhury S, Ketcham SA, Schroer TA, Lander GC | Nature structural & molecular biology | 25751425 | Nat Struct Mol Biol | 2015 Apr | https://www.ncbi.nlm.nih.gov/pubmed/25751425 |
Structural basis for distinct operational modes and protease activation in AAA+ protease Lon. | Shin M, Puchades C, Asmita A, Puri N, Adjei E, Wiseman RL, Karzai AW, Lander GC | Science advances | 32490208 | Sci Adv | 2020 May | https://www.ncbi.nlm.nih.gov/pubmed/32490208 |
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel. | Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY | Nature communications | 31431622 | Nat Commun | 2019 Aug 20 | https://www.ncbi.nlm.nih.gov/pubmed/31431622 |
The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer. | Chen KC, Qu S, Chowdhury S, Noxon IC, Schonhoft JD, Plate L, Powers ET, Kelly JW, Lander GC, Wiseman RL | The EMBO journal | 28655754 | EMBO J | 2017 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/28655754 |
Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry. | Rollins MF, Chowdhury S, Carter J, Golden SM, Miettinen HM, Santiago-Frangos A, Faith D, Lawrence CM, Lander GC, Wiedenheft B | Molecular cell | 30872121 | Mol Cell | 2019 Apr 4 | https://www.ncbi.nlm.nih.gov/pubmed/30872121 |
Isolation of yeast complex IV in native lipid nanodiscs. | Smirnova IA, Sjöstrand D, Li F, Björck M, Schäfer J, Östbye H, Högbom M, von Ballmoos C, Lander GC, Ädelroth P, Brzezinski P | Biochimica et biophysica acta | 27620332 | Biochim Biophys Acta | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27620332 |
Cryo-EM structure of a mitochondrial calcium uniporter. | Yoo J, Wu M, Yin Y, Herzik MA Jr, Lander GC, Lee SY | Science (New York, N.Y.) | 29954988 | Science | 2018 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/29954988 |
Conformational ensemble of the human TRPV3 ion channel. | Zubcevic L, Herzik MA Jr, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY | Nature communications | 30429472 | Nat Commun | 2018 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/30429472 |
Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing. | Puchades C, Rampello AJ, Shin M, Giuliano CJ, Wiseman RL, Glynn SE, Lander GC | Science (New York, N.Y.) | 29097521 | Science | 2017 Nov 3 | https://www.ncbi.nlm.nih.gov/pubmed/29097521 |
The molecular principles governing the activity and functional diversity of AAA+ proteins. | Puchades C, Sandate CR, Lander GC | Nature reviews. Molecular cell biology | 31754261 | Nat Rev Mol Cell Biol | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/31754261 |
Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility. | Grotjahn DA, Chowdhury S, Xu Y, McKenney RJ, Schroer TA, Lander GC | Nature structural & molecular biology | 29416113 | Nat Struct Mol Biol | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29416113 |
High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM. | Herzik MA Jr, Wu M, Lander GC | Nature communications | 30833564 | Nat Commun | 2019 Mar 4 | https://www.ncbi.nlm.nih.gov/pubmed/30833564 |
Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity. | Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B | Proceedings of the National Academy of Sciences of the United States of America | 28438998 | Proc Natl Acad Sci U S A | 2017 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/28438998 |
Achieving better-than-3-Å resolution by single-particle cryo-EM at 200 keV. | Herzik MA Jr, Wu M, Lander GC | Nature methods | 28991891 | Nat Methods | 2017 Nov | https://www.ncbi.nlm.nih.gov/pubmed/28991891 |
Exploring applications of crowdsourcing to cryo-EM. | Bruggemann J, Lander GC, Su AI | Journal of structural biology | 29486249 | J Struct Biol | 2018 Jul | https://www.ncbi.nlm.nih.gov/pubmed/29486249 |
DNA-Assembled Core-Satellite Upconverting-Metal-Organic Framework Nanoparticle Superstructures for Efficient Photodynamic Therapy. | He L, Brasino M, Mao C, Cho S, Park W, Goodwin AP, Cha JN | Small (Weinheim an der Bergstrasse, Germany) | 28481463 | Small | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28481463 |
Depolymerizable Poly(O-vinyl carbamate-alt-sulfones) as Customizable Macromolecular Scaffolds for Mucosal Drug Delivery. | Kumar K, Castaño EJ, Weidner AR, Yildirim A, Goodwin AP | ACS macro letters | 28480130 | ACS Macro Lett | 2016 May 17 | https://www.ncbi.nlm.nih.gov/pubmed/28480130 |
Understanding Acoustic Cavitation Initiation by Porous Nanoparticles: Toward Nanoscale Agents for Ultrasound Imaging and Therapy. | Yildirim A, Chattaraj R, Blum NT, Goodwin AP | Chemistry of materials : a publication of the American Chemical Society | 28484307 | Chem Mater | 2016 Aug 23 | https://www.ncbi.nlm.nih.gov/pubmed/28484307 |
TiO(2)-Capped Gold Nanorods for Plasmon-Enhanced Production of Reactive Oxygen Species and Photothermal Delivery of Chemotherapeutic Agents. | He L, Mao C, Brasino M, Harguindey A, Park W, Goodwin AP, Cha JN | ACS applied materials & interfaces | 30044085 | ACS Appl Mater Interfaces | 2018 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/30044085 |
Temperature-Responsive Hydrophobic Silica Nanoparticle Ultrasound Contrast Agents Directed by Phospholipid Phase Behavior. | Blum NT, Yildirim A, Gyorkos C, Shi D, Cai A, Chattaraj R, Goodwin AP | ACS applied materials & interfaces | 31012297 | ACS Appl Mater Interfaces | 2019 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/31012297 |
Enzymes Photo-Cross-Linked to Live Cell Receptors Retain Activity and EGFR Inhibition after Both Internalization and Recycling. | Roy S, Brasino M, Beirne JM, Harguindey A, Chapnick DA, Liu X, Cha JN, Goodwin AP | Bioconjugate chemistry | 31840981 | Bioconjug Chem | 2020 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/31840981 |
Phospholipid Capped Mesoporous Nanoparticles for Targeted High Intensity Focused Ultrasound Ablation. | Yildirim A, Chattaraj R, Blum NT, Shi D, Kumar K, Goodwin AP | Advanced healthcare materials | 28699308 | Adv Healthc Mater | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28699308 |
Selective Vaporization of Superheated Nanodroplets for Rapid, Sensitive, Acoustic Biosensing. | Chattaraj R, Mohan P, Besmer JD, Goodwin AP | Advanced healthcare materials | 26084414 | Adv Healthc Mater | 2015 Aug 26 | https://www.ncbi.nlm.nih.gov/pubmed/26084414 |
Anti-EGFR Affibodies with Site-Specific Photo-Cross-Linker Incorporation Show Both Directed Target-Specific Photoconjugation and Increased Retention in Tumors. | Brasino M, Roy S, Erbse AH, He L, Mao C, Park W, Cha JN, Goodwin AP | Journal of the American Chemical Society | 30203972 | J Am Chem Soc | 2018 Sep 19 | https://www.ncbi.nlm.nih.gov/pubmed/30203972 |
Light-Driven Catalytic Upgrading of Butanol in a Biohybrid Photoelectrochemical System. | Harris AW, Yehezkeli O, Hafenstine GR, Goodwin AP, Cha JN | ACS sustainable chemistry & engineering | 33133786 | ACS Sustain Chem Eng | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/33133786 |
Conversion of Ethanol to 2-Ethylhexenal at Ambient Conditions Using Tandem, Biphasic Catalysis. | Hafenstine GR, Harris AW, Ma K, Cha JN, Goodwin AP | ACS sustainable chemistry & engineering | 33224638 | ACS Sustain Chem Eng | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/33224638 |
Nanoparticles Formed by Acoustic Destruction of Microbubbles and Their Utilization for Imaging and Effects on Therapy by High Intensity Focused Ultrasound. | Blum NT, Yildirim A, Chattaraj R, Goodwin AP | Theranostics | 28255360 | Theranostics | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28255360 |
Surface-Templated Nanobubbles Protect Proteins from Surface-Mediated Denaturation. | Bull DS, Kienle DF, Chaparro Sosa AF, Nelson N, Roy S, Cha JN, Schwartz DK, Kaar JL, Goodwin AP | The journal of physical chemistry letters | 31067058 | J Phys Chem Lett | 2019 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/31067058 |
Contact Line Pinning Is Not Required for Nanobubble Stability on Copolymer Brushes. | Bull DS, Nelson N, Konetski D, Bowman CN, Schwartz DK, Goodwin AP | The journal of physical chemistry letters | 30010342 | J Phys Chem Lett | 2018 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/30010342 |
Phospholipid-Coated Hydrophobic Mesoporous Silica Nanoparticles Enhance Thrombectomy by High-Intensity Focused Ultrasound with Low Production of Embolism-Inducing Clot Debris. | Blum NT, Gyorkos CM, Narowetz SJ, Mueller EN, Goodwin AP | ACS applied materials & interfaces | 31556582 | ACS Appl Mater Interfaces | 2019 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/31556582 |
Catalytic Upgrading in Bacteria-Compatible Conditions via a Biocompatible Aldol Condensation. | Domaille DW, Hafenstine GR, Greer MA, Goodwin AP, Cha JN | ACS sustainable chemistry & engineering | 28480149 | ACS Sustain Chem Eng | 2016 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/28480149 |
Phase Behavior of Mixed Lipid Monolayers on Perfluorocarbon Nanoemulsions and its Effect on Acoustic Contrast. | Chattaraj R, Goldscheitter GM, Yildirim A, Goodwin AP | RSC advances | 28603605 | RSC Adv | 2016 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/28603605 |
Stable Encapsulation of Air in Mesoporous Silica Nanoparticles: Fluorocarbon-Free Nanoscale Ultrasound Contrast Agents. | Yildirim A, Chattaraj R, Blum NT, Goldscheitter GM, Goodwin AP | Advanced healthcare materials | 26990167 | Adv Healthc Mater | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26990167 |
Polyacrylamide Hydrogels Produce Hydrogen Peroxide from Osmotic Swelling in Aqueous Media. | Parameswar AV, Fitch KR, Bull DS, Duke VR, Goodwin AP | Biomacromolecules | 30052430 | Biomacromolecules | 2018 Aug 13 | https://www.ncbi.nlm.nih.gov/pubmed/30052430 |
Nanoparticle-Mediated Acoustic Cavitation Enables High Intensity Focused Ultrasound Ablation Without Tissue Heating. | Yildirim A, Shi D, Roy S, Blum NT, Chattaraj R, Cha JN, Goodwin AP | ACS applied materials & interfaces | 30339360 | ACS Appl Mater Interfaces | 2018 Oct 31 | https://www.ncbi.nlm.nih.gov/pubmed/30339360 |
Design and Application of Stimulus-Responsive Droplets and Bubbles Stabilized by Phospholipid Monolayers. | Chattaraj R, Blum NT, Goodwin AP | Current opinion in colloid & interface science | 31086500 | Curr Opin Colloid Interface Sci | 2019 Apr | https://www.ncbi.nlm.nih.gov/pubmed/31086500 |
Click Nucleic Acid Mediated Loading of Prodrug Activating Enzymes in PEG-PLGA Nanoparticles for Combination Chemotherapy. | Harguindey A, Roy S, Harris AW, Fairbanks BD, Goodwin AP, Bowman CN, Cha JN | Biomacromolecules | 30884222 | Biomacromolecules | 2019 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/30884222 |
Multicatalytic, Light-Driven Upgrading of Butanol to 2-Ethylhexenal and Hydrogen under Mild Aqueous Conditions. | Hafenstine GR, Ma K, Harris AW, Yehezkeli O, Park E, Domaille DW, Cha JN, Goodwin AP | ACS catalysis | 33133753 | ACS Catal | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/33133753 |
Mutually-Reactive, Fluorogenic Hydrocyanine/Quinone Reporter Pairs for In-Solution Biosensing via Nanodroplet Association. | Chattaraj R, Mohan P, Livingston CM, Besmer JD, Kumar K, Goodwin AP | ACS applied materials & interfaces | 26710239 | ACS Appl Mater Interfaces | 2016 Jan 13 | https://www.ncbi.nlm.nih.gov/pubmed/26710239 |
Alternating Sulfone Copolymers Depolymerize in Response to Both Chemical and Mechanical Stimuli. | Kumar K, Goodwin AP | ACS macro letters | 28480129 | ACS Macro Lett | 2015 Sep 15 | https://www.ncbi.nlm.nih.gov/pubmed/28480129 |
Solar Photocatalytic Phenol Polymerization and Hydrogen Generation for Flocculation of Wastewater Impurities. | Hafenstine GR, Patalano RE, Harris AW, Jiang G, Ma K, Goodwin AP, Cha JN | ACS applied polymer materials | 37206614 | ACS Appl Polym Mater | 2019 Jun 14 | https://www.ncbi.nlm.nih.gov/pubmed/37206614 |
Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy. | Xu H, Tong Z, Ye Q, Sun T, Hong Z, Zhang L, Bortnick A, Cho S, Beuzer P, Axelrod J, Hu Q, Wang M, Evans SM, Murre C, Lu LF, Sun S, Corbett KD, Cang H | Proceedings of the National Academy of Sciences of the United States of America | 31444302 | Proc Natl Acad Sci U S A | 2019 Sep 10 | https://www.ncbi.nlm.nih.gov/pubmed/31444302 |
Type I Interferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell-Mediated Tumor Killing. | Fan JB, Miyauchi S, Xu HZ, Liu D, Kim LJY, Burkart C, Cheng H, Arimoto KI, Yan M, Zhou Y, Győrffy B, Knobeloch KP, Rich JN, Cang H, Fu XD, Zhang DE | Cancer discovery | 31974171 | Cancer Discov | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31974171 |
Adiabatic far-field sub-diffraction imaging. | Cang H, Salandrino A, Wang Y, Zhang X | Nature communications | 26258769 | Nat Commun | 2015 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/26258769 |
Ritterostatin G(N) 1(N) , a Cephalostatin-Ritterazine Bis-steroidal Pyrazine Hybrid, Selectively Targets GRP78. | Ambrose AJ, Santos EA, Jimenez PC, Rocha DD, Wilke DV, Beuzer P, Axelrod J, Kumar Kanduluru A, Fuchs PL, Cang H, Costa-Lotufo LV, Chapman E, La Clair JJ | Chembiochem : a European journal of chemical biology | 28074539 | Chembiochem | 2017 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/28074539 |
Single dish gradient screening of small molecule localization. | Beuzer P, Axelrod J, Trzoss L, Fenical W, Dasari R, Evidente A, Kornienko A, Cang H, La Clair JJ | Organic & biomolecular chemistry | 27530345 | Org Biomol Chem | 2016 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/27530345 |
Color-Coded Super-Resolution Small-Molecule Imaging. | Beuzer P, La Clair JJ, Cang H | Chembiochem : a European journal of chemical biology | 26994590 | Chembiochem | 2016 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/26994590 |
Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling. | Gimple RC, Kidwell RL, Kim LJY, Sun T, Gromovsky AD, Wu Q, Wolf M, Lv D, Bhargava S, Jiang L, Prager BC, Wang X, Ye Q, Zhu Z, Zhang G, Dong Z, Zhao L, Lee D, Bi J, Sloan AE, Mischel PS, Brown JM, Cang H, Huan T, Mack SC, Xie Q, Rich JN | Cancer discovery | 31201181 | Cancer Discov | 2019 Sep | https://www.ncbi.nlm.nih.gov/pubmed/31201181 |
Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence. | Liu S, Cao W, Niu Y, Luo J, Zhao Y, Hu Z, Zong C | eLife | 33983114 | Elife | 2021 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/33983114 |
Single-cell total-RNA profiling unveils regulatory hubs of transcription factors. | Niu Y, Luo J, Zong C | Nature communications | 39009595 | Nat Commun | 2024 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/39009595 |
Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1. | Jen HI, Hill MC, Tao L, Sheng K, Cao W, Zhang H, Yu HV, Llamas J, Zong C, Martin JF, Segil N, Groves AK | eLife | 31033441 | Elife | 2019 Apr 29 | https://www.ncbi.nlm.nih.gov/pubmed/31033441 |
Droplet-based transcriptome profiling of individual synapses. | Niu M, Cao W, Wang Y, Zhu Q, Luo J, Wang B, Zheng H, Weitz DA, Zong C | Nature biotechnology | 36646931 | Nat Biotechnol | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36646931 |
Fibroblast heterogeneity and its impact on extracellular matrix and immune landscape remodeling in cancer. | Yamauchi M, Gibbons DL, Zong C, Fradette JJ, Bota-Rabassedas N, Kurie JM | Matrix biology : journal of the International Society for Matrix Biology | 32442601 | Matrix Biol | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32442601 |
Single-cell Damagenome Profiling by Linear Copying and Splitting based Whole Genome Amplification (LCS-WGA). | Niu Y, Zhu Q, Zong C | Bio-protocol | 35434195 | Bio Protoc | 2022 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/35434195 |
Single-cell damagenome profiling unveils vulnerable genes and functional pathways in human genome toward DNA damage. | Zhu Q, Niu Y, Gundry M, Zong C | Science advances | 34215579 | Sci Adv | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34215579 |
Protein engineering of Cas9 for enhanced function. | Oakes BL, Nadler DC, Savage DF | Methods in enzymology | 25398355 | Methods Enzymol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25398355 |
Rapid and Programmable Protein Mutagenesis Using Plasmid Recombineering. | Higgins SA, Ouonkap SVY, Savage DF | ACS synthetic biology | 28707884 | ACS Synth Biol | 2017 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/28707884 |
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch. | Oakes BL, Nadler DC, Flamholz A, Fellmann C, Staahl BT, Doudna JA, Savage DF | Nature biotechnology | 27136077 | Nat Biotechnol | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27136077 |
Rapid construction of metabolite biosensors using domain-insertion profiling. | Nadler DC, Morgan SA, Flamholz A, Kortright KE, Savage DF | Nature communications | 27470466 | Nat Commun | 2016 Jul 29 | https://www.ncbi.nlm.nih.gov/pubmed/27470466 |
Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors. | Huang TP, Zhao KT, Miller SM, Gaudelli NM, Oakes BL, Fellmann C, Savage DF, Liu DR | Nature biotechnology | 31110355 | Nat Biotechnol | 2019 Jun | https://www.ncbi.nlm.nih.gov/pubmed/31110355 |
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification. | Oakes BL, Fellmann C, Rishi H, Taylor KL, Ren SM, Nadler DC, Yokoo R, Arkin AP, Doudna JA, Savage DF | Cell | 30633905 | Cell | 2019 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/30633905 |
Biofuel metabolic engineering with biosensors. | Morgan SA, Nadler DC, Yokoo R, Savage DF | Current opinion in chemical biology | 27768949 | Curr Opin Chem Biol | 2016 Dec | https://www.ncbi.nlm.nih.gov/pubmed/27768949 |
Cas14: Big Advances from Small CRISPR Proteins. | Savage DF | Biochemistry | 30740978 | Biochemistry | 2019 Feb 26 | https://www.ncbi.nlm.nih.gov/pubmed/30740978 |
Imaging and three-dimensional reconstruction of chemical groups inside a protein complex using atomic force microscopy. | Kim D, Sahin O | Nature nanotechnology | 25664622 | Nat Nanotechnol | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25664622 |
Cellular nanoscale stiffness patterns governed by intracellular forces. | Mandriota N, Friedsam C, Jones-Molina JA, Tatem KV, Ingber DE, Sahin O | Nature materials | 31209386 | Nat Mater | 2019 Oct | https://www.ncbi.nlm.nih.gov/pubmed/31209386 |
Calibration of T-shaped atomic force microscope cantilevers using the thermal noise method. | Kim Y, Mandriota N, Goodnight D, Sahin O | The Review of scientific instruments | 32872926 | Rev Sci Instrum | 2020 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/32872926 |
Live-cell quantitative imaging of proteome degradation by stimulated Raman scattering. | Shen Y, Xu F, Wei L, Hu F, Min W | Angewandte Chemie (International ed. in English) | 24737659 | Angew Chem Int Ed Engl | 2014 May 26 | https://www.ncbi.nlm.nih.gov/pubmed/24737659 |
Operando and three-dimensional visualization of anion depletion and lithium growth by stimulated Raman scattering microscopy. | Cheng Q, Wei L, Liu Z, Ni N, Sang Z, Zhu B, Xu W, Chen M, Miao Y, Chen LQ, Min W, Yang Y | Nature communications | 30061610 | Nat Commun | 2018 Jul 30 | https://www.ncbi.nlm.nih.gov/pubmed/30061610 |
Optical imaging of metabolic dynamics in animals. | Shi L, Zheng C, Shen Y, Chen Z, Silveira ES, Zhang L, Wei M, Liu C, de Sena-Tomas C, Targoff K, Min W | Nature communications | 30082908 | Nat Commun | 2018 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/30082908 |
Multicolor live-cell chemical imaging by isotopically edited alkyne vibrational palette. | Chen Z, Paley DW, Wei L, Weisman AL, Friesner RA, Nuckolls C, Min W | Journal of the American Chemical Society | 24849912 | J Am Chem Soc | 2014 Jun 4 | https://www.ncbi.nlm.nih.gov/pubmed/24849912 |
Spectral tracing of deuterium for imaging glucose metabolism. | Zhang L, Shi L, Shen Y, Miao Y, Wei M, Qian N, Liu Y, Min W | Nature biomedical engineering | 31036888 | Nat Biomed Eng | 2019 May | https://www.ncbi.nlm.nih.gov/pubmed/31036888 |
Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering. | Long R, Zhang L, Shi L, Shen Y, Hu F, Zeng C, Min W | Chemical communications (Cambridge, England) | 29218356 | Chem Commun (Camb) | 2018 Jan 7 | https://www.ncbi.nlm.nih.gov/pubmed/29218356 |
Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering. | Wei L, Hu F, Shen Y, Chen Z, Yu Y, Lin CC, Wang MC, Min W | Nature methods | 24584195 | Nat Methods | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24584195 |
Live-cell vibrational imaging of choline metabolites by stimulated Raman scattering coupled with isotope-based metabolic labeling. | Hu F, Wei L, Zheng C, Shen Y, Min W | The Analyst | 24555181 | Analyst | 2014 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/24555181 |
Bioorthogonal chemical imaging of metabolic activities in live mammalian hippocampal tissues with stimulated Raman scattering. | Hu F, Lamprecht MR, Wei L, Morrison B, Min W | Scientific reports | 28000773 | Sci Rep | 2016 Dec 21 | https://www.ncbi.nlm.nih.gov/pubmed/28000773 |
Vibrational Imaging of Glucose Uptake Activity in Live Cells and Tissues by Stimulated Raman Scattering. | Hu F, Chen Z, Zhang L, Shen Y, Wei L, Min W | Angewandte Chemie (International ed. in English) | 26207979 | Angew Chem Int Ed Engl | 2015 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/26207979 |
Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging. | Hu F, Brucks SD, Lambert TH, Campos LM, Min W | Chemical communications (Cambridge, England) | 28474031 | Chem Commun (Camb) | 2017 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/28474031 |
Supermultiplexed optical imaging and barcoding with engineered polyynes. | Hu F, Zeng C, Long R, Miao Y, Wei L, Xu Q, Min W | Nature methods | 29334378 | Nat Methods | 2018 Mar | https://www.ncbi.nlm.nih.gov/pubmed/29334378 |
Metabolic activity induces membrane phase separation in endoplasmic reticulum. | Shen Y, Zhao Z, Zhang L, Shi L, Shahriar S, Chan RB, Di Paolo G, Min W | Proceedings of the National Academy of Sciences of the United States of America | 29196526 | Proc Natl Acad Sci U S A | 2017 Dec 19 | https://www.ncbi.nlm.nih.gov/pubmed/29196526 |
Vibrational imaging of newly synthesized proteins in live cells by stimulated Raman scattering microscopy. | Wei L, Yu Y, Shen Y, Wang MC, Min W | Proceedings of the National Academy of Sciences of the United States of America | 23798434 | Proc Natl Acad Sci U S A | 2013 Jul 9 | https://www.ncbi.nlm.nih.gov/pubmed/23798434 |
Super-multiplex vibrational imaging. | Wei L, Chen Z, Shi L, Long R, Anzalone AV, Zhang L, Hu F, Yuste R, Cornish VW, Min W | Nature | 28424513 | Nature | 2017 Apr 27 | https://www.ncbi.nlm.nih.gov/pubmed/28424513 |
Imaging complex protein metabolism in live organisms by stimulated Raman scattering microscopy with isotope labeling. | Wei L, Shen Y, Xu F, Hu F, Harrington JK, Targoff KL, Min W | ACS chemical biology | 25560305 | ACS Chem Biol | 2015 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/25560305 |
Bioorthogonal chemical imaging of metabolic changes during epithelial-mesenchymal transition of cancer cells by stimulated Raman scattering microscopy. | Zhang L, Min W | Journal of biomedical optics | 29043713 | J Biomed Opt | 2017 Oct | https://www.ncbi.nlm.nih.gov/pubmed/29043713 |
Applications of vibrational tags in biological imaging by Raman microscopy. | Zhao Z, Shen Y, Hu F, Min W | The Analyst | 28875184 | Analyst | 2017 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/28875184 |
Electronic Preresonance Stimulated Raman Scattering Microscopy. | Wei L, Min W | The journal of physical chemistry letters | 30001137 | J Phys Chem Lett | 2018 Aug 2 | https://www.ncbi.nlm.nih.gov/pubmed/30001137 |
A ratiometric Raman probe for live-cell imaging of hydrogen sulfide in mitochondria by stimulated Raman scattering. | Zeng C , Hu F , Long R , Min W | The Analyst | 30246812 | Analyst | 2018 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/30246812 |
Live-Cell Bioorthogonal Chemical Imaging: Stimulated Raman Scattering Microscopy of Vibrational Probes. | Wei L, Hu F, Chen Z, Shen Y, Zhang L, Min W | Accounts of chemical research | 27486796 | Acc Chem Res | 2016 Aug 16 | https://www.ncbi.nlm.nih.gov/pubmed/27486796 |
Reducing X-Ray Induced Oxidative Damages in Fibroblasts with Graphene Oxide. | Qiao Y, Zhang P, Wang C, Ma L, Su M | Nanomaterials (Basel, Switzerland) | 25530873 | Nanomaterials (Basel) | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25530873 |
Monte Carlo and analytic simulations in nanoparticle-enhanced radiation therapy. | Paro AD, Hossain M, Webster TJ, Su M | International journal of nanomedicine | 27695329 | Int J Nanomedicine | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27695329 |
Enhanced radiation therapy with internalized polyelectrolyte modified nanoparticles. | Zhang P, Qiao Y, Wang C, Ma L, Su M | Nanoscale | 25032891 | Nanoscale | 2014 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/25032891 |
Whole slide imaging of circulating tumor cells captured on a capillary microchannel device. | Zheng Y, Li Q, Hu W, Liao J, Zheng G, Su M | Lab on a chip | 31621763 | Lab Chip | 2019 Nov 21 | https://www.ncbi.nlm.nih.gov/pubmed/31621763 |
Nanoparticle location and material dependent dose enhancement in X-ray radiation therapy. | Hossain M, Su M | The journal of physical chemistry. C, Nanomaterials and interfaces | 23393610 | J Phys Chem C Nanomater Interfaces | 2012 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/23393610 |
Three-dimensional microtissues as an in vitro model for personalized radiation therapy. | Qiu Y, Ning D, Zhang P, Curly S, Qiao Y, Ma L, Su M | The Analyst | 28812074 | Analyst | 2017 Sep 25 | https://www.ncbi.nlm.nih.gov/pubmed/28812074 |
Multiplexed detection of molecular biomarkers with phase-change nanoparticles. | Su M | Nanomedicine (London, England) | 23394155 | Nanomedicine (Lond) | 2013 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23394155 |
Surface charge controlled nucleoli selective staining with nanoscale carbon dots. | Zhu Z, Li Q, Li P, Xun X, Zheng L, Ning D, Su M | PloS one | 31150413 | PLoS One | 2019 | https://www.ncbi.nlm.nih.gov/pubmed/31150413 |
Cationic surface modification of gold nanoparticles for enhanced cellular uptake and X-ray radiation therapy. | Wang C, Sun A, Qiao Y, Zhang P, Ma L, Su M | Journal of materials chemistry. B | 26512323 | J Mater Chem B | 2015 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/26512323 |
Chip-scale alignment of long DNA nanofibers on a patterned self-assembled monolayer. | Xia J, Su M | Lab on a chip | 28820213 | Lab Chip | 2017 Sep 26 | https://www.ncbi.nlm.nih.gov/pubmed/28820213 |
Polydopamine Nanoparticles for Combined Chemo- and Photothermal Cancer Therapy. | Zhu Z, Su M | Nanomaterials (Basel, Switzerland) | 28661423 | Nanomaterials (Basel) | 2017 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/28661423 |
A noncanonical polyamine from bacteria antagonizes animal mitochondrial function. | Nauta KM, Gates DR, Weiland M, Mechan-Llontop ME, Wang X, Nguyen KP, Isaguirre C, Genjdar MR, Sheldon RD, Krawczyk CM, Burton NO | bioRxiv : the preprint server for biology | 38746390 | bioRxiv | 2025 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/38746390 |
An ultrathin membrane mediates tissue-specific morphogenesis and barrier function in a human kidney chip. | Mou X, Shah J, Roye Y, Du C, Musah S | Science advances | 38838141 | Sci Adv | 2024 Jun 7 | https://www.ncbi.nlm.nih.gov/pubmed/38838141 |
Kidney Disease Modeling with Organoids and Organs-on-Chips. | Musah S, Bhattacharya R, Himmelfarb J | Annual review of biomedical engineering | 38424088 | Annu Rev Biomed Eng | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38424088 |
Fenestrated Endothelial Cells across Organs: Insights into Kidney Function and Disease. | Mou X, Leeman SM, Roye Y, Miller C, Musah S | International journal of molecular sciences | 39201792 | Int J Mol Sci | 2024 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/39201792 |
Unleashing the power of biomaterials to enhance organoid differentiation and function. | Musah S, Arzaghi H | Nature methods | 39179910 | Nat Methods | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39179910 |
Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations. | Bhattacharya R, Ward T, Kalejaiye TD, Mishra A, Leeman S, Arzaghi H, Seidman JG, Seidman CE, Musah S | bioRxiv : the preprint server for biology | 39211233 | bioRxiv | 2024 Aug 6 | https://www.ncbi.nlm.nih.gov/pubmed/39211233 |
Editorial: Environmental rhythms at the host-microbe interface. | Brooks JF, Heath-Heckman E, Kuang Z | Frontiers in genetics | 37811149 | Front Genet | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/37811149 |
HDAC3 integrates TGF-β and microbial cues to program tuft cell biogenesis and diurnal rhythms in mucosal immune surveillance. | Zhang J, Wang G, Ma J, Duan Y, Sharma SA, Oladejo S, Ma X, Arellano G, Orchard RC, Reese TA, Kuang Z | Science immunology | 39331726 | Sci Immunol | 2024 Sep 27 | https://www.ncbi.nlm.nih.gov/pubmed/39331726 |
Chemical interplay between gut microbiota and epigenetics: Implications in circadian biology. | Sharma SA, Oladejo SO, Kuang Z | Cell chemical biology | 38776923 | Cell Chem Biol | 2025 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/38776923 |
A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan. | Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, Markovski A, Sun S, Yao H, Sankaran VG, Gladyshev VN, Brooke RT, Horvath S, Griffith EC, Hrvatin S | bioRxiv : the preprint server for biology | 38585858 | bioRxiv | 2024 Mar 25 | https://www.ncbi.nlm.nih.gov/pubmed/38585858 |
A torpor-like state in mice slows blood epigenetic aging and prolongs healthspan. | Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, Markovski A, Sun S, Yao H, Sankaran VG, Gladyshev VN, Brooke RT, Horvath S, Griffith EC, Hrvatin S | Nature aging | 40055478 | Nat Aging | 2025 Mar | https://www.ncbi.nlm.nih.gov/pubmed/40055478 |
Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death. | Lam B, Kajderowicz KM, Keys HR, Roessler JM, Frenkel EM, Kirkland A, Bisht P, El-Brolosy MA, Jaenisch R, Bell GW, Weissman JS, Griffith EC, Hrvatin S | bioRxiv : the preprint server for biology | 39091747 | bioRxiv | 2024 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/39091747 |
Building a kidney tree: Functional collecting duct from human pluripotent stem cells. | Li Z, Lindström NO | Developmental cell | 36220079 | Dev Cell | 2022 Oct 10 | https://www.ncbi.nlm.nih.gov/pubmed/36220079 |
Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. | Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, Zhang CC, Schreiber ME, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Lindström NO, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, McMahon AP, Li Z | bioRxiv : the preprint server for biology | 37293038 | bioRxiv | 2023 May 25 | https://www.ncbi.nlm.nih.gov/pubmed/37293038 |
Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease. | Huang B, Zeng Z, Kim S, Fausto CC, Koppitch K, Li H, Li Z, Chen X, Guo J, Zhang CC, Ma T, Medina P, Schreiber ME, Xia MW, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, Lindström NO, McMahon AP, Li Z | Cell stem cell | 38692273 | Cell Stem Cell | 2024 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/38692273 |
Engineering multicellular living systems-a Keystone Symposia report. | Cable J, Arlotta P, Parker KK, Hughes AJ, Goodwin K, Mummery CL, Kamm RD, Engle SJ, Tagle DA, Boj SF, Stanton AE, Morishita Y, Kemp ML, Norfleet DA, May EE, Lu A, Bashir R, Feinberg AW, Hull SM, Gonzalez AL, Blatchley MR, Montserrat Pulido N, Morizane R, McDevitt TC, Mishra D, Mulero-Russe A | Annals of the New York Academy of Sciences | 36177947 | Ann N Y Acad Sci | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/36177947 |
Kidney development to kidney organoids and back again. | Gupta N, Morizane R | Seminars in cell & developmental biology | 34627669 | Semin Cell Dev Biol | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34627669 |
Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury. | Ettou S, Jung YL, Miyoshi T, Jain D, Hiratsuka K, Schumacher V, Taglienti ME, Morizane R, Park PJ, Kreidberg JA | Science advances | 32754639 | Sci Adv | 2020 Jul | https://www.ncbi.nlm.nih.gov/pubmed/32754639 |
Cryopreservation of human kidney organoids. | Mashouf P, Tabibzadeh N, Kuraoka S, Oishi H, Morizane R | Cellular and molecular life sciences : CMLS | 39023560 | Cell Mol Life Sci | 2024 Jul 18 | https://www.ncbi.nlm.nih.gov/pubmed/39023560 |
Kidney organoids in translational medicine: Disease modeling and regenerative medicine. | Miyoshi T, Hiratsuka K, Saiz EG, Morizane R | Developmental dynamics : an official publication of the American Association of Anatomists | 30843293 | Dev Dyn | 2020 Jan | https://www.ncbi.nlm.nih.gov/pubmed/30843293 |
3D proximal tubule-on-chip model derived from kidney organoids with improved drug uptake. | Aceves JO, Heja S, Kobayashi K, Robinson SS, Miyoshi T, Matsumoto T, Schäffers OJM, Morizane R, Lewis JA | Scientific reports | 36056134 | Sci Rep | 2022 Sep 2 | https://www.ncbi.nlm.nih.gov/pubmed/36056134 |
Advancements in therapeutic development: kidney organoids and organs on a chip. | Tabibzadeh N, Morizane R | Kidney international | 38296026 | Kidney Int | 2024 Apr | https://www.ncbi.nlm.nih.gov/pubmed/38296026 |
Generation of glucocorticoid-producing cells derived from human pluripotent stem cells. | Ruiz-Babot G, Eceiza A, Abollo-Jiménez F, Malyukov M, Carlone DL, Borges K, Da Costa AR, Qarin S, Matsumoto T, Morizane R, Skarnes WC, Ludwig B, Chapple PJ, Guasti L, Storr HL, Bornstein SR, Breault DT | Cell reports methods | 37924815 | Cell Rep Methods | 2023 Nov 20 | https://www.ncbi.nlm.nih.gov/pubmed/37924815 |
Functional maturation of kidney organoid tubules: PIEZO1-mediated Ca(2+) signaling. | Carrisoza-Gaytan R, Kroll KT, Hiratsuka K, Gupta NR, Morizane R, Lewis JA, Satlin LM | American journal of physiology. Cell physiology | 36745528 | Am J Physiol Cell Physiol | 2023 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/36745528 |
A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis. | Yoon SH, Meyer MB, Arevalo C, Tekguc M, Zhang C, Wang JS, Castro Andrade CD, Strauss K, Sato T, Benkusky NA, Lee SM, Berdeaux R, Foretz M, Sundberg TB, Xavier RJ, Adelmann CH, Brooks DJ, Anselmo A, Sadreyev RI, Rosales IA, Fisher DE, Gupta N, Morizane R, Greka A, Pike JW, Mannstadt M, Wein MN | The Journal of clinical investigation | 36862513 | J Clin Invest | 2023 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/36862513 |
Strategies for Improving Vascularization in Kidney Organoids: A Review of Current Trends. | Konoe R, Morizane R | Biology | 37106704 | Biology (Basel) | 2023 Mar 26 | https://www.ncbi.nlm.nih.gov/pubmed/37106704 |
Advancing preclinical drug evaluation through automated 3D imaging for high-throughput screening with kidney organoids. | Oishi H, Tabibzadeh N, Morizane R | Biofabrication | 38547531 | Biofabrication | 2024 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/38547531 |
The NIH Somatic Cell Genome Editing program. | Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J, SCGE Consortium | Nature | 33828315 | Nature | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33828315 |
3D kidney organoids for bench-to-bedside translation. | Gupta N, Dilmen E, Morizane R | Journal of molecular medicine (Berlin, Germany) | 33034708 | J Mol Med (Berl) | 2021 Apr | https://www.ncbi.nlm.nih.gov/pubmed/33034708 |
Live functional assays reveal longitudinal maturation of transepithelial transport in kidney organoids. | Rizki-Safitri A, Gupta N, Hiratsuka K, Kobayashi K, Zhang C, Ida K, Satlin LM, Morizane R | Frontiers in cell and developmental biology | 36046340 | Front Cell Dev Biol | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/36046340 |
Kidney organoids: a pioneering model for kidney diseases. | Tekguc M, Gaal RCV, Uzel SGM, Gupta N, Riella LV, Lewis JA, Morizane R | Translational research : the journal of laboratory and clinical medicine | 35750295 | Transl Res | 2022 Dec | https://www.ncbi.nlm.nih.gov/pubmed/35750295 |
Immune-infiltrated kidney organoid-on-chip model for assessing T cell bispecific antibodies. | Kroll KT, Mata MM, Homan KA, Micallef V, Carpy A, Hiratsuka K, Morizane R, Moisan A, Gubler M, Walz AC, Marrer-Berger E, Lewis JA | Proceedings of the National Academy of Sciences of the United States of America | 37603766 | Proc Natl Acad Sci U S A | 2023 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/37603766 |
ATP/ADP biosensor organoids for drug nephrotoxicity assessment. | Susa K, Kobayashi K, Galichon P, Matsumoto T, Tamura A, Hiratsuka K, Gupta NR, Yazdi IK, Bonventre JV, Morizane R | Frontiers in cell and developmental biology | 36936695 | Front Cell Dev Biol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36936695 |
Bioengineered Kidney Models: Methods and Functional Assessments. | Rizki-Safitri A, Traitteur T, Morizane R | Function (Oxford, England) | 35330622 | Function (Oxf) | 2021 | https://www.ncbi.nlm.nih.gov/pubmed/35330622 |
Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair. | Gupta N, Matsumoto T, Hiratsuka K, Garcia Saiz E, Galichon P, Miyoshi T, Susa K, Tatsumoto N, Yamashita M, Morizane R | Science translational medicine | 35235339 | Sci Transl Med | 2022 Mar 2 | https://www.ncbi.nlm.nih.gov/pubmed/35235339 |
Navigating the kidney organoid: insights into assessment and enhancement of nephron function. | Tabibzadeh N, Satlin LM, Jain S, Morizane R | American journal of physiology. Renal physiology | 37767571 | Am J Physiol Renal Physiol | 2023 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/37767571 |
Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery. | Hiratsuka K, Miyoshi T, Kroll KT, Gupta NR, Valerius MT, Ferrante T, Yamashita M, Lewis JA, Morizane R | Science advances | 36129975 | Sci Adv | 2022 Sep 23 | https://www.ncbi.nlm.nih.gov/pubmed/36129975 |
Brain Defense of Glycemia in Health and Diabetes. | Mirzadeh Z, Faber C | Diabetes | 39401393 | Diabetes | 2024 Dec 1 | https://www.ncbi.nlm.nih.gov/pubmed/39401393 |
Leptin receptor neurons in the dorsomedial hypothalamus regulate diurnal patterns of feeding, locomotion, and metabolism. | Faber CL, Deem JD, Phan BA, Doan TP, Ogimoto K, Mirzadeh Z, Schwartz MW, Morton GJ | eLife | 33527893 | Elife | 2021 Feb 2 | https://www.ncbi.nlm.nih.gov/pubmed/33527893 |
Central Nervous System Control of Glucose Homeostasis: A Therapeutic Target for Type 2 Diabetes? | Mirzadeh Z, Faber CL, Schwartz MW | Annual review of pharmacology and toxicology | 34990204 | Annu Rev Pharmacol Toxicol | 2022 Jan 6 | https://www.ncbi.nlm.nih.gov/pubmed/34990204 |
Multiplexed single-cell analysis reveals prognostic and nonprognostic T cell types in human colorectal cancer. | Masuda K, Kornberg A, Miller J, Lin S, Suek N, Botella T, Secener KA, Bacarella AM, Cheng L, Ingham M, Rosario V, Al-Mazrou AM, Lee-Kong SA, Kiran RP, Stoeckius M, Smibert P, Del Portillo A, Oberstein PE, Sims PA, Yan KS, Han A | JCI insight | 35192548 | JCI Insight | 2022 Apr 8 | https://www.ncbi.nlm.nih.gov/pubmed/35192548 |
R-SPONDIN2(+) mesenchymal cells form the bud tip progenitor niche during human lung development. | Hein RFC, Wu JH, Holloway EM, Frum T, Conchola AS, Tsai YH, Wu A, Fine AS, Miller AJ, Szenker-Ravi E, Yan KS, Kuo CJ, Glass I, Reversade B, Spence JR | Developmental cell | 35679862 | Dev Cell | 2022 Jul 11 | https://www.ncbi.nlm.nih.gov/pubmed/35679862 |
Microbial-Dependent Recruitment of Immature Myeloid Cells Promotes Intestinal Regeneration. | Jiang Z, Waterbury QT, Malagola E, Fu N, Kim W, Ochiai Y, Wu F, Guha C, Shawber CJ, Yan KS, Wang TC | Cellular and molecular gastroenterology and hepatology | 37898454 | Cell Mol Gastroenterol Hepatol | 2024 | https://www.ncbi.nlm.nih.gov/pubmed/37898454 |
COVID-19 Gastrointestinal Symptoms and Attenuation of the Immune Response to SARS-CoV-2. | Miller J, Yan KS | Gastroenterology | 33753106 | Gastroenterology | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33753106 |
3D Organoids: An Untapped Platform for Studying Host-Microbiome Interactions in Esophageal Cancers. | Flashner S, Yan KS, Nakagawa H | Microorganisms | 34835308 | Microorganisms | 2021 Oct 20 | https://www.ncbi.nlm.nih.gov/pubmed/34835308 |
Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells. | Capdevila C, Miller J, Cheng L, Kornberg A, George JJ, Lee H, Botella T, Moon CS, Murray JW, Lam S, Calderon RI, Malagola E, Whelan G, Lin CS, Han A, Wang TC, Sims PA, Yan KS | Cell | 38848677 | Cell | 2024 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/38848677 |
Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury. | Malagola E, Vasciaveo A, Ochiai Y, Kim W, Zheng B, Zanella L, Wang ALE, Middelhoff M, Nienhüser H, Deng L, Wu F, Waterbury QT, Belin B, LaBella J, Zamechek LB, Wong MH, Li L, Guha C, Cheng CW, Yan KS, Califano A, Wang TC | Cell | 38848678 | Cell | 2024 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/38848678 |
Single-Cell Transcriptional Profiling of the Intestinal Epithelium. | Capdevila C, Calderon RI, Bush EC, Sheldon-Collins K, Sims PA, Yan KS | Methods in molecular biology (Clifton, N.J.) | 32705639 | Methods Mol Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32705639 |
Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration. | Maan ZN, Rinkevich Y, Barrera J, Chen K, Henn D, Foster D, Bonham CA, Padmanabhan J, Sivaraj D, Duscher D, Hu M, Yan K, Januszyk M, Longaker MT, Weissman IL, Gurtner GC | Journal of clinical medicine | 34575372 | J Clin Med | 2021 Sep 20 | https://www.ncbi.nlm.nih.gov/pubmed/34575372 |
Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids. | Flashner S, Martin C, Matsuura N, Shimonosono M, Tomita Y, Morimoto M, Okolo O, Yu VX, Parikh AS, Klein-Szanto AJP, Yan K, Gabre JT, Lu C, Momen-Heravi F, Rustgi AK, Nakagawa H | Journal of visualized experiments : JoVE | 36622034 | J Vis Exp | 2022 Dec 23 | https://www.ncbi.nlm.nih.gov/pubmed/36622034 |
Presentation of the Julius M. Friedenwald Medal to Timothy C. Wang, MD, AGAF. | Abrams J, Camilleri M, Merchant J, Rustgi AK, Yan K | Gastroenterology | 35443933 | Gastroenterology | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35443933 |
Single-Cell Studies of Intestinal Stem Cell Heterogeneity During Homeostasis and Regeneration. | Norkin M, Capdevila C, Calderon RI, Su T, Trifas M, Ordóñez-Morán P, Yan KS | Methods in molecular biology (Clifton, N.J.) | 32705640 | Methods Mol Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32705640 |
Cellular origins and lineage relationships of the intestinal epithelium. | Capdevila C, Trifas M, Miller J, Anderson T, Sims PA, Yan KS | American journal of physiology. Gastrointestinal and liver physiology | 34431400 | Am J Physiol Gastrointest Liver Physiol | 2021 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/34431400 |
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease. | Kornberg A, Botella T, Moon CS, Rao S, Gelbs J, Cheng L, Miller J, Bacarella AM, García-Vilas JA, Vargas J, Yu X, Krupska I, Bush E, Garcia-Carrasquillo R, Lebwohl B, Krishnareddy S, Lewis S, Green PHR, Bhagat G, Yan KS, Han A | Science immunology | 37450575 | Sci Immunol | 2023 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/37450575 |
Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope. | Lovelace JW, Ma J, Yadav S, Chhabria K, Shen H, Pang Z, Qi T, Sehgal R, Zhang Y, Bali T, Vaissiere T, Tan S, Liu Y, Rumbaugh G, Ye L, Kleinfeld D, Stringer C, Augustine V | Nature | 37914931 | Nature | 2023 Nov | https://www.ncbi.nlm.nih.gov/pubmed/37914931 |
Xiphoid nucleus of the midline thalamus controls cold-induced food seeking. | Lal NK, Le P, Aggarwal S, Zhang A, Wang K, Qi T, Pang Z, Yang D, Nudell V, Yeo GW, Banks AS, Ye L | Nature | 37587337 | Nature | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37587337 |
In situ identification of cellular drug targets in mammalian tissue. | Pang Z, Schafroth MA, Ogasawara D, Wang Y, Nudell V, Lal NK, Yang D, Wang K, Herbst DM, Ha J, Guijas C, Blankman JL, Cravatt BF, Ye L | Cell | 35483372 | Cell | 2022 May 12 | https://www.ncbi.nlm.nih.gov/pubmed/35483372 |
The Afferent Function of Adipose Innervation. | Wang Y, Ye L | Diabetes | 38377447 | Diabetes | 2024 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/38377447 |
The role of somatosensory innervation of adipose tissues. | Wang Y, Leung VH, Zhang Y, Nudell VS, Loud M, Servin-Vences MR, Yang D, Wang K, Moya-Garzon MD, Li VL, Long JZ, Patapoutian A, Ye L | Nature | 36045288 | Nature | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/36045288 |
Brainstem Dbh(+) neurons control allergen-induced airway hyperreactivity. | Su Y, Xu J, Zhu Z, Chin J, Xu L, Yu H, Nudell V, Dash B, Moya EA, Ye L, Nimmerjahn A, Sun X | Nature | 38987587 | Nature | 2024 Jul | https://www.ncbi.nlm.nih.gov/pubmed/38987587 |
Cortical Representations of Conspecific Sex Shape Social Behavior. | Kingsbury L, Huang S, Raam T, Ye LS, Wei D, Hu RK, Ye L, Hong W | Neuron | 32663438 | Neuron | 2020 Sep 9 | https://www.ncbi.nlm.nih.gov/pubmed/32663438 |
Acetylcholine-synthesizing macrophages in subcutaneous fat are regulated by β(2) -adrenergic signaling. | Knights AJ, Liu S, Ma Y, Nudell VS, Perkey E, Sorensen MJ, Kennedy RT, Maillard I, Ye L, Jun H, Wu J | The EMBO journal | 34459015 | EMBO J | 2021 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/34459015 |
A protocol to visualize on-target specific drug binding in mammalian tissue with cellular resolution using tissue clearing and click chemistry. | Pang Z, Ye L | STAR protocols | 36313539 | STAR Protoc | 2022 Dec 16 | https://www.ncbi.nlm.nih.gov/pubmed/36313539 |
Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity. | Yang D, Wang Y, Qi T, Zhang X, Shen L, Ma J, Pang Z, Lal NK, McClatchy DB, Seradj SH, Leung VH, Wang K, Xie Y, Polli FS, Maximov A, Gonzalez OC, de Lecea L, Cline HT, Augustine V, Yates JR 3rd, Ye L | Neuron | 38266644 | Neuron | 2024 Mar 20 | https://www.ncbi.nlm.nih.gov/pubmed/38266644 |
TESOS: an integrated approach for uniform mesoscale imaging. | Wang Y, Ye L | Cell research | 38168641 | Cell Res | 2024 Feb | https://www.ncbi.nlm.nih.gov/pubmed/38168641 |
Xiphoid nucleus of the midline thalamus controls cold-induced food seeking. | Lal NK, Le P, Aggarwal S, Zhang A, Wang K, Qi T, Pang Z, Yang D, Nudell V, Yeo GW, Banks AS, Ye L | bioRxiv : the preprint server for biology | 36993706 | bioRxiv | 2023 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/36993706 |
Somatosensory innervation of adipose tissues. | Wang Y, Ye L | Physiology & behavior | 36965573 | Physiol Behav | 2023 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/36965573 |
A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation. | Wang Y, Zhang Y, Leung V, Seradj SH, Sonmez U, Servin-Vences R, Lipomi D, Ye L, Patapoutian A | bioRxiv : the preprint server for biology | 39605632 | bioRxiv | 2024 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/39605632 |
HYBRiD: hydrogel-reinforced DISCO for clearing mammalian bodies. | Nudell V, Wang Y, Pang Z, Lal NK, Huang M, Shaabani N, Kanim W, Teijaro J, Maximov A, Ye L | Nature methods | 35347322 | Nat Methods | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35347322 |
Illuminating spatial pharmacology with in situ drug imaging. | Pang Z, Ye L | Clinical and translational medicine | 36030504 | Clin Transl Med | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/36030504 |
Narrative engineering of the liver. | Lee IS, Takebe T | Current opinion in genetics & development | 35700688 | Curr Opin Genet Dev | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35700688 |
Cellotype-phenotype associations using 'organoid villages'. | Kimura M, Takebe T | Trends in endocrinology and metabolism: TEM | 38575442 | Trends Endocrinol Metab | 2024 Jun | https://www.ncbi.nlm.nih.gov/pubmed/38575442 |
Polygenic architecture informs potential vulnerability to drug-induced liver injury. | Koido M, Kawakami E, Fukumura J, Noguchi Y, Ohori M, Nio Y, Nicoletti P, Aithal GP, Daly AK, Watkins PB, Anayama H, Dragan Y, Shinozawa T, Takebe T | Nature medicine | 32895570 | Nat Med | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/32895570 |
Human liver model systems in a dish. | Thompson WL, Takebe T | Development, growth & differentiation | 33423319 | Dev Growth Differ | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33423319 |
Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids. | Miao Y, Tan C, Pek NM, Yu Z, Iwasawa K, Kechele DO, Sundaram N, Pastrana-Gomez V, Kishimoto K, Yang MC, Jiang C, Tchieu J, Whitsett JA, McCracken KW, Rottier RJ, Kotton DN, Helmrath MA, Wells JM, Takebe T, Zorn AM, Chen YW, Guo M, Gu M | bioRxiv : the preprint server for biology | 38370768 | bioRxiv | 2024 Feb 7 | https://www.ncbi.nlm.nih.gov/pubmed/38370768 |
POLYseq: A poly(β-amino ester)-based vector for multifunctional cellular barcoding. | Dunn A, Cai Y, Iwasawa K, Kimura M, Takebe T | Stem cell reports | 34450040 | Stem Cell Reports | 2021 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/34450040 |
Organoid transplant approaches for the liver. | Reza HA, Okabe R, Takebe T | Transplant international : official journal of the European Society for Organ Transplantation | 34614263 | Transpl Int | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/34614263 |
En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH. | Kimura M, Iguchi T, Iwasawa K, Dunn A, Thompson WL, Yoneyama Y, Chaturvedi P, Zorn AM, Wintzinger M, Quattrocelli M, Watanabe-Chailland M, Zhu G, Fujimoto M, Kumbaji M, Kodaka A, Gindin Y, Chung C, Myers RP, Subramanian GM, Hwa V, Takebe T | Cell | 36240780 | Cell | 2022 Oct 27 | https://www.ncbi.nlm.nih.gov/pubmed/36240780 |
In vitro human cell-based models: What can they do and what are their limitations? | Lutolf MP, Radisic M, Beekman J, Huh DD, Huch M, Turco MY, Tahmasebi Birgani ZN, Gao D, Yao R, Lin H, Takebe T | Cell | 39178827 | Cell | 2024 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/39178827 |
Inter-cellular mRNA Transfer Alters Human Pluripotent Stem Cell State. | Yoneyama Y, Zhang RR, Kimura M, Cai Y, Adam M, Parameswaran S, Masaki H, Mizuno N, Bhadury J, Maezawa S, Ochiai H, Nakauchi H, Potter SS, Weirauch MT, Takebe T | bioRxiv : the preprint server for biology | 38979277 | bioRxiv | 2024 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/38979277 |
Eicosatetraynoic Acid Regulates Profibrotic Pathways in an Induced Pluripotent Stem Cell-Derived Macrophage-Human Intestinal Organoid Model of Crohn's Disease. | Jurickova I, Dreskin BW, Angerman E, Bonkowski E, Nguyen J, Villarreal R, Tominaga K, Iwasawa K, Braun T, Takebe T, Helmrath MA, Haberman Y, Wells JM, Denson LA | Journal of Crohn's & colitis | 39212594 | J Crohns Colitis | 2025 Feb 4 | https://www.ncbi.nlm.nih.gov/pubmed/39212594 |
Self-Assembled Generation of Multi-zonal Liver Organoids from Human Pluripotent Stem Cells. | Al Reza H, Santangelo C, Al Reza A, Iwasawa K, Sachiko S, Glaser K, Bondoc A, Merola J, Takebe T | bioRxiv : the preprint server for biology | 39257824 | bioRxiv | 2024 Aug 30 | https://www.ncbi.nlm.nih.gov/pubmed/39257824 |
Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells. | Rezvani M, Lewis K, Quach S, Iwasawa K, Weihs J, Reza H, Cai Y, Kimura M, Zhang R, Milton Y, Chaturvedi P, Thorner K, Nayak RC, Munera JO, Kramer P, Davis B, Balamurugan A, Ait Ahmed Y, Finke M, Behncke RY, Guillot A, Haegerling R, Polansky J, Bufler P, Cancelas J, Wells J, Yoshimoto M, Takebe T | bioRxiv : the preprint server for biology | 39416072 | bioRxiv | 2024 Oct 12 | https://www.ncbi.nlm.nih.gov/pubmed/39416072 |
Generation of multi-cellular human liver organoids from pluripotent stem cells. | Thompson WL, Takebe T | Methods in cell biology | 32586449 | Methods Cell Biol | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32586449 |
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection. | Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Murphy A, Iskhakova M, Fernando MB, Powell SK, Deans PJM, Javidfar B, Peter C, Møller R, Uhl SA, Garcia MF, Kimura M, Iwasawa K, Crary JF, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ | Stem cell reports | 33636110 | Stem Cell Reports | 2021 Mar 9 | https://www.ncbi.nlm.nih.gov/pubmed/33636110 |
Fetal liver hematopoiesis: from development to delivery. | Lewis K, Yoshimoto M, Takebe T | Stem cell research & therapy | 33597015 | Stem Cell Res Ther | 2021 Feb 17 | https://www.ncbi.nlm.nih.gov/pubmed/33597015 |
The promise of human organoids in the digestive system. | Funata M, Nio Y, Erion DM, Thompson WL, Takebe T | Cell death and differentiation | 33204011 | Cell Death Differ | 2021 Jan | https://www.ncbi.nlm.nih.gov/pubmed/33204011 |
Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. | Koike H, Iwasawa K, Ouchi R, Maezawa M, Kimura M, Kodaka A, Nishii S, Thompson WL, Takebe T | Nature protocols | 33432231 | Nat Protoc | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33432231 |
High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids. | Shinozawa T, Kimura M, Cai Y, Saiki N, Yoneyama Y, Ouchi R, Koike H, Maezawa M, Zhang RR, Dunn A, Ferguson A, Togo S, Lewis K, Thompson WL, Asai A, Takebe T | Gastroenterology | 33039464 | Gastroenterology | 2021 Feb | https://www.ncbi.nlm.nih.gov/pubmed/33039464 |
A Pillar and Perfusion Plate Platform for Robust Human Organoid Culture and Analysis. | Kang SY, Kimura M, Shrestha S, Lewis P, Lee S, Cai Y, Joshi P, Acharya P, Liu J, Yang Y, Sanchez JG, Ayyagari S, Alsberg E, Wells JM, Takebe T, Lee MY | Advanced healthcare materials | 37616035 | Adv Healthc Mater | 2024 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37616035 |
Organogenesis in vitro. | Iwasawa K, Takebe T | Current opinion in cell biology | 34352726 | Curr Opin Cell Biol | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34352726 |
Synthesis and application of POLYseq for profiling human liver organoids. | Dunn AW, Cai Y, Iwasawa K, Kimura M, Takebe T | STAR protocols | 34934958 | STAR Protoc | 2021 Dec 17 | https://www.ncbi.nlm.nih.gov/pubmed/34934958 |
Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems. | Kishimoto K, Iwasawa K, Sorel A, Ferran-Heredia C, Han L, Morimoto M, Wells JM, Takebe T, Zorn AM | Nature protocols | 35978039 | Nat Protoc | 2022 Nov | https://www.ncbi.nlm.nih.gov/pubmed/35978039 |
Synthetic augmentation of bilirubin metabolism in human pluripotent stem cell-derived liver organoids. | Reza HA, Farooqui Z, Reza AA, Conroy C, Iwasawa K, Ogura Y, Okita K, Osafune K, Takebe T | Stem cell reports | 37832542 | Stem Cell Reports | 2023 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/37832542 |
ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH. | Liu YJ, Kimura M, Li X, Sulc J, Wang Q, Rodríguez-López S, Scantlebery AML, Strotjohann K, Gallart-Ayala H, Vijayakumar A, Myers RP, Ivanisevic J, Houtkooper RH, Subramanian GM, Takebe T, Auwerx J | Journal of hepatology | 39181211 | J Hepatol | 2025 Feb | https://www.ncbi.nlm.nih.gov/pubmed/39181211 |
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids. | Marsee A, Roos FJM, Verstegen MMA, HPB Organoid Consortium, Gehart H, de Koning E, Lemaigre F, Forbes SJ, Peng WC, Huch M, Takebe T, Vallier L, Clevers H, van der Laan LJW, Spee B | Cell stem cell | 33961769 | Cell Stem Cell | 2021 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/33961769 |
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection. | Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Iskhakova M, Fernando MB, Deans PJM, Powell SK, Javidfar B, Murphy A, Peter C, Møeller R, Garcia MF, Kimura M, Iwasawa K, Crary J, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ | bioRxiv : the preprint server for biology | 32995783 | bioRxiv | 2020 Sep 21 | https://www.ncbi.nlm.nih.gov/pubmed/32995783 |
Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19. | Kawakami E, Saiki N, Yoneyama Y, Moriya C, Maezawa M, Kawamura S, Kinebuchi A, Kono T, Funata M, Sakoda A, Kondo S, Ebihara T, Matsumoto H, Togami Y, Ogura H, Sugihara F, Okuzaki D, Kojima T, Deguchi S, Vallee S, McQuade S, Islam R, Natarajan M, Ishigaki H, Nakayama M, Nguyen CT, Kitagawa Y, Wu Y, Mori K, Hishiki T, Takasaki T, Itoh Y, Takayama K, Nio Y, Takebe T | Cell stem cell | 37802037 | Cell Stem Cell | 2023 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/37802037 |
Self-Organization of Sinusoidal Vessels in Pluripotent Stem Cell-derived Human Liver Bud Organoids. | Saiki N, Nio Y, Yoneyama Y, Kawamura S, Iwasawa K, Kawakami E, Araki K, Fukumura J, Sakairi T, Kono T, Ohmura R, Koido M, Funata M, Thompson WL, Cruz-Encarnacion P, Chen YW, Takebe T | bioRxiv : the preprint server for biology | 39005378 | bioRxiv | 2024 Jul 4 | https://www.ncbi.nlm.nih.gov/pubmed/39005378 |
Intercellular mRNA transfer alters the human pluripotent stem cell state. | Yoneyama Y, Zhang RR, Maezawa M, Masaki H, Kimura M, Cai Y, Adam M, Parameswaran S, Mizuno N, Bhadury J, Maezawa S, Ochiai H, Nakauchi H, Potter SS, Weirauch MT, Takebe T | Proceedings of the National Academy of Sciences of the United States of America | 39841146 | Proc Natl Acad Sci U S A | 2025 Jan 28 | https://www.ncbi.nlm.nih.gov/pubmed/39841146 |
Organoid-guided precision hepatology for metabolic liver disease. | Osonoi S, Takebe T | Journal of hepatology | 38237864 | J Hepatol | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38237864 |
Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids. | Sheth M, Sharma M, Lehn M, Reza H, Takebe T, Takiar V, Wise-Draper T, Esfandiari L | APL bioengineering | 39092008 | APL Bioeng | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39092008 |
Autoreactivity in naïve human fetal B cells is associated with commensal bacteria recognition. | Chen JW, Rice TA, Bannock JM, Bielecka AA, Strauss JD, Catanzaro JR, Wang H, Menard LC, Anolik JH, Palm NW, Meffre E | Science (New York, N.Y.) | 32675374 | Science | 2020 Jul 17 | https://www.ncbi.nlm.nih.gov/pubmed/32675374 |
Within-host evolution of a gut pathobiont facilitates liver translocation. | Yang Y, Nguyen M, Khetrapal V, Sonnert ND, Martin AL, Chen H, Kriegel MA, Palm NW | Nature | 35831502 | Nature | 2022 Jul | https://www.ncbi.nlm.nih.gov/pubmed/35831502 |
Small Molecule Metabolites at the Host-Microbiota Interface. | Bishai JD, Palm NW | Journal of immunology (Baltimore, Md. : 1950) | 34544815 | J Immunol | 2021 Oct 1 | https://www.ncbi.nlm.nih.gov/pubmed/34544815 |
Gut instincts in neuroimmunity from the eighteenth to twenty-first centuries. | Nguyen M, Palm NW | Seminars in immunopathology | 35786740 | Semin Immunopathol | 2022 Sep | https://www.ncbi.nlm.nih.gov/pubmed/35786740 |
Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites. | Cao Y, Oh J, Xue M, Huh WJ, Wang J, Gonzalez-Hernandez JA, Rice TA, Martin AL, Song D, Crawford JM, Herzon SB, Palm NW | Science (New York, N.Y.) | 36302024 | Science | 2022 Oct 28 | https://www.ncbi.nlm.nih.gov/pubmed/36302024 |
Interspecies commensal interactions have nonlinear impacts on host immunity. | Rice TA, Bielecka AA, Nguyen MT, Rosen CE, Song D, Sonnert ND, Yang Y, Cao Y, Khetrapal V, Catanzaro JR, Martin AL, Rashed SA, Leopold SR, Hao L, Yu X, van Dijk D, Ring AM, Flavell RA, de Zoete MR, Palm NW | Cell host & microbe | 35640610 | Cell Host Microbe | 2022 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/35640610 |
Highly multiplexed bioactivity screening reveals human and microbiota metabolome-GPCRome interactions. | Chen H, Rosen CE, González-Hernández JA, Song D, Potempa J, Ring AM, Palm NW | Cell | 37321219 | Cell | 2023 Jul 6 | https://www.ncbi.nlm.nih.gov/pubmed/37321219 |
Diagnosis, Education, and Care of Patients with APOL1-Associated Nephropathy: A Delphi Consensus and Systematic Review. | Freedman BI, Burke W, Divers J, Eberhard L, Gadegbeku CA, Gbadegesin R, Hall ME, Jones-Smith T, Knight R, Kopp JB, Kovesdy CP, Norris KC, Olabisi OA, Roberts GV, Sedor JR, Blacksher E | Journal of the American Society of Nephrology : JASN | 33853887 | J Am Soc Nephrol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33853887 |
Kidney Disease-Associated APOL1 Variants Have Dose-Dependent, Dominant Toxic Gain-of-Function. | Datta S, Kataria R, Zhang JY, Moore S, Petitpas K, Mohamed A, Zahler N, Pollak MR, Olabisi OA | Journal of the American Society of Nephrology : JASN | 32675303 | J Am Soc Nephrol | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/32675303 |
JAK inhibitor blocks COVID-19 cytokine-induced JAK/STAT/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids. | Nystrom SE, Li G, Datta S, Soldano KL, Silas D, Weins A, Hall G, Thomas DB, Olabisi OA | JCI insight | 35472001 | JCI Insight | 2022 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/35472001 |
Collapsing Glomerulopathy in Identical Twins With Lupus and High-Risk Apolipoprotein L1 (APOL1) Genotype. | DeOliveira M, Feeney C, Leahy C, Nystrom S, Howell DN, Farouk SS, Wu M, Olabisi OA, Sparks MA | Kidney international reports | 34514214 | Kidney Int Rep | 2021 Sep | https://www.ncbi.nlm.nih.gov/pubmed/34514214 |
APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease. | Datta S, Antonio BM, Zahler NH, Theile JW, Krafte D, Zhang H, Rosenberg PB, Chaves AB, Muoio DM, Zhang G, Silas D, Li G, Soldano K, Nystrom S, Ferreira D, Miller SE, Bain JR, Muehlbauer MJ, Ilkayeva O, Becker TC, Hohmeier HE, Newgard CB, Olabisi OA | The Journal of clinical investigation | 38227370 | J Clin Invest | 2024 Jan 16 | https://www.ncbi.nlm.nih.gov/pubmed/38227370 |
APOL1 channel blocker reduces proteinuria in FSGS. | Olabisi OA | Kidney international | 37224918 | Kidney Int | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/37224918 |
APOL1 High-Risk Genotype is Not Associated With New or Worsening of Proteinuria or Kidney Function Decline Following COVID-19 Vaccination. | Nystrom SE, Soldano KL, Rockett M, Datta S, Li G, Silas D, Garrett ME, Ashley-Koch AE, Olabisi OA | Kidney international reports | 39291186 | Kidney Int Rep | 2024 Sep | https://www.ncbi.nlm.nih.gov/pubmed/39291186 |
APOL1-associated kidney disease in northern Nigerians with treated HIV infection. | Olabisi OA, Freedman BI | Kidney international | 34154709 | Kidney Int | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/34154709 |
APOL1 Variant and Kidney Disease-Reply. | Hopper T, Olabisi OA | JAMA | 39186317 | JAMA | 2024 Sep 24 | https://www.ncbi.nlm.nih.gov/pubmed/39186317 |
Prevalence and Impact of APOL1 Kidney Risk Variants in West Africa : Insights for Global Kidney Disease Assessment and Treatment. | Martinelli E, Westland R, Olabisi OA, Sanna-Cherchi S | Journal of the American Society of Nephrology : JASN | 39602366 | J Am Soc Nephrol | 2025 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/39602366 |
APOL1-Mediated Kidney Disease. | Hopper T, Olabisi OA | JAMA | 38662391 | JAMA | 2024 May 21 | https://www.ncbi.nlm.nih.gov/pubmed/38662391 |
CD70-Targeted Micelles Enhance HIF2α siRNA Delivery and Inhibit Oncogenic Functions in Patient-Derived Clear Cell Renal Carcinoma Cells. | Trac N, Oh HS, Jones LI, Caliliw R, Ohtake S, Shuch B, Chung EJ | Molecules (Basel, Switzerland) | 36500549 | Molecules | 2022 Dec 2 | https://www.ncbi.nlm.nih.gov/pubmed/36500549 |
Long-term, in vivo therapeutic effects of a single dose of miR-145 micelles for atherosclerosis. | Chin DD, Patel N, Lee W, Kanaya S, Cook J, Chung EJ | Bioactive materials | 37122900 | Bioact Mater | 2023 Sep | https://www.ncbi.nlm.nih.gov/pubmed/37122900 |
Improving kidney targeting: The influence of nanoparticle physicochemical properties on kidney interactions. | Huang Y, Wang J, Jiang K, Chung EJ | Journal of controlled release : official journal of the Controlled Release Society | 33892054 | J Control Release | 2021 Jun 10 | https://www.ncbi.nlm.nih.gov/pubmed/33892054 |
Overcoming physiological barriers by nanoparticles for intravenous drug delivery to the lymph nodes. | Trac N, Chung EJ | Experimental biology and medicine (Maywood, N.J.) | 33957802 | Exp Biol Med (Maywood) | 2021 Nov | https://www.ncbi.nlm.nih.gov/pubmed/33957802 |
Exosomes in Atherosclerosis, a Double-Edged Sword: Their Role in Disease Pathogenesis and Their Potential as Novel Therapeutics. | Patel N, Chin DD, Chung EJ | The AAPS journal | 34312734 | AAPS J | 2021 Jul 26 | https://www.ncbi.nlm.nih.gov/pubmed/34312734 |
The effect of size, charge, and peptide ligand length on kidney targeting by small, organic nanoparticles. | Huang Y, Jiang K, Zhang X, Chung EJ | Bioengineering & translational medicine | 33005739 | Bioeng Transl Med | 2020 Sep | https://www.ncbi.nlm.nih.gov/pubmed/33005739 |
Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease. | Wang J, Chin D, Poon C, Mancino V, Pham J, Li H, Ho PY, Hallows KR, Chung EJ | Journal of controlled release : official journal of the Controlled Release Society | 33127449 | J Control Release | 2021 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/33127449 |
Clinical progress of nanomedicine-based RNA therapies. | Lim SA, Cox A, Tung M, Chung EJ | Bioactive materials | 35310381 | Bioact Mater | 2022 Jun | https://www.ncbi.nlm.nih.gov/pubmed/35310381 |
Immunization using ApoB-100 peptide-linked nanoparticles reduces atherosclerosis. | Chyu KY, Zhao X, Zhou J, Dimayuga PC, Lio NW, Cercek B, Trac NT, Chung EJ, Shah PK | JCI insight | 35536648 | JCI Insight | 2022 Jun 8 | https://www.ncbi.nlm.nih.gov/pubmed/35536648 |
CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation. | Trac N, Chen LY, Zhang A, Liao CP, Poon C, Wang J, Ando Y, Joo J, Garri C, Shen K, Kani K, Gross ME, Chung EJ | Journal of controlled release : official journal of the Controlled Release Society | 33011241 | J Control Release | 2021 Jan 10 | https://www.ncbi.nlm.nih.gov/pubmed/33011241 |
miR-145 micelles mitigate atherosclerosis by modulating vascular smooth muscle cell phenotype. | Chin DD, Poon C, Wang J, Joo J, Ong V, Jiang Z, Cheng K, Plotkin A, Magee GA, Chung EJ | Biomaterials | 33892346 | Biomaterials | 2021 Jun | https://www.ncbi.nlm.nih.gov/pubmed/33892346 |
Investigation of Basolateral Targeting Micelles for Drug Delivery Applications in Polycystic Kidney Disease. | Huang Y, Osouli A, Pham J, Mancino V, O'Grady C, Khan T, Chaudhuri B, Pastor-Soler NM, Hallows KR, Chung EJ | Biomacromolecules | 38652072 | Biomacromolecules | 2024 May 13 | https://www.ncbi.nlm.nih.gov/pubmed/38652072 |
In vitro delivery of mTOR inhibitors by kidney-targeted micelles for autosomal dominant polycystic kidney disease. | Cox A, Tung M, Li H, Hallows KR, Chung EJ | SLAS technology | 36804177 | SLAS Technol | 2023 Aug | https://www.ncbi.nlm.nih.gov/pubmed/36804177 |
Transdermal Delivery of Kidney-Targeting Nanoparticles Using Dissolvable Microneedles. | Tripathy N, Wang J, Tung M, Conway C, Chung EJ | Cellular and molecular bioengineering | 33184578 | Cell Mol Bioeng | 2020 Oct | https://www.ncbi.nlm.nih.gov/pubmed/33184578 |
Targeting and therapeutic peptide-based strategies for polycystic kidney disease. | Wang J, Tripathy N, Chung EJ | Advanced drug delivery reviews | 32866560 | Adv Drug Deliv Rev | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32866560 |
Spotlight on Genetic Kidney Diseases: A Call for Drug Delivery and Nanomedicine Solutions. | Trac N, Ashraf A, Giblin J, Prakash S, Mitragotri S, Chung EJ | ACS nano | 36988207 | ACS Nano | 2023 Apr 11 | https://www.ncbi.nlm.nih.gov/pubmed/36988207 |
Oral delivery of nanomedicine for genetic kidney disease. | Huang Y, Wang J, Mancino V, Pham J, O'Grady C, Li H, Jiang K, Chin D, Poon C, Ho PY, Gyarmati G, Peti-Peterdi J, Hallows KR, Chung EJ | PNAS nexus | 38807632 | PNAS Nexus | 2024 May | https://www.ncbi.nlm.nih.gov/pubmed/38807632 |
Hydroxyapatite-binding micelles for the detection of vascular calcification in atherosclerosis. | Chin DD, Wang J, Mel de Fontenay M, Plotkin A, Magee GA, Chung EJ | Journal of materials chemistry. B | 31553027 | J Mater Chem B | 2019 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/31553027 |
Combining Metformin and Drug-Loaded Kidney-Targeting Micelles for Polycystic Kidney Disease. | Jiang K, Huang Y, Chung EJ | Cellular and molecular bioengineering | 36660586 | Cell Mol Bioeng | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/36660586 |
Therapeutic Response of miR-145 Micelles on Patient-Derived Vascular Smooth Muscle Cells. | Patel N, Chin DD, Magee GA, Chung EJ | Frontiers in digital health | 35783597 | Front Digit Health | 2022 | https://www.ncbi.nlm.nih.gov/pubmed/35783597 |
Strategies to deliver RNA by nanoparticles for therapeutic potential. | Cox A, Lim SA, Chung EJ | Molecular aspects of medicine | 34366123 | Mol Aspects Med | 2022 Feb | https://www.ncbi.nlm.nih.gov/pubmed/34366123 |
Collagenase-Cleavable Peptide Amphiphile Micelles as a Novel Theranostic Strategy in Atherosclerosis. | Chin DD, Poon C, Trac N, Wang J, Cook J, Joo J, Jiang Z, Maria NSS, Jacobs RE, Chung EJ | Advanced therapeutics | 34295964 | Adv Ther (Weinh) | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/34295964 |
Calcium-binding nanoparticles for vascular disease. | Chin DD, Chowdhuri S, Chung EJ | Regenerative engineering and translational medicine | 31106257 | Regen Eng Transl Med | 2019 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31106257 |
Caenorhabditis elegans as a Model for Microbiome Research. | Zhang F, Berg M, Dierking K, Félix MA, Shapira M, Samuel BS, Schulenburg H | Frontiers in microbiology | 28386252 | Front Microbiol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/28386252 |
Population scale nucleic acid delivery to Caenorhabditis elegans via electroporation. | Khodakova AS, Vilchis DV, Blackburn D, Amanor F, Samuel BS | G3 (Bethesda, Md.) | 33872353 | G3 (Bethesda) | 2021 Jul 14 | https://www.ncbi.nlm.nih.gov/pubmed/33872353 |
Natural genetic variation drives microbiome selection in the Caenorhabditis elegans gut. | Zhang F, Weckhorst JL, Assié A, Hosea C, Ayoub CA, Khodakova AS, Cabrera ML, Vidal Vilchis D, Félix MA, Samuel BS | Current biology : CB | 34048707 | Curr Biol | 2021 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/34048707 |
Interleukin-1β secretion induced by mucosa-associated gut commensal bacteria promotes intestinal barrier repair. | Wu WH, Kim M, Chang LC, Assie A, Saldana-Morales FB, Zegarra-Ruiz DF, Norwood K, Samuel BS, Diehl GE | Gut microbes | 34989321 | Gut Microbes | 2022 Jan-Dec | https://www.ncbi.nlm.nih.gov/pubmed/34989321 |
Metabolic model predictions enable targeted microbiome manipulation through precision prebiotics. | Marinos G, Hamerich IK, Debray R, Obeng N, Petersen C, Taubenheim J, Zimmermann J, Blackburn D, Samuel BS, Dierking K, Franke A, Laudes M, Waschina S, Schulenburg H, Kaleta C | Microbiology spectrum | 38230938 | Microbiol Spectr | 2024 Feb 6 | https://www.ncbi.nlm.nih.gov/pubmed/38230938 |
Caenorhabditis elegans endorse bacterial nanocellulose fibers as functional dietary Fiber reducing lipid markers. | Muñoz-Juan A, Assié A, Esteve-Codina A, Gut M, Benseny-Cases N, Samuel BS, Dalfó E, Laromaine A | Carbohydrate polymers | 38388067 | Carbohydr Polym | 2024 May 1 | https://www.ncbi.nlm.nih.gov/pubmed/38388067 |
Application of Flow Vermimetry for Quantification and Analysis of the Caenorhabditis elegans Gut Microbiome. | Zhang F, Blackburn D, Hosea CN, Assié A, Samuel BS | Journal of visualized experiments : JoVE | 37067276 | J Vis Exp | 2023 Mar 31 | https://www.ncbi.nlm.nih.gov/pubmed/37067276 |
Emergence of dauer larvae in Caenorhabditis elegans disrupts continuity of host-microbiome interactions. | Bodkhe R, Trang K, Hammond S, Jung DK, Shapira M | FEMS microbiology ecology | 39516048 | FEMS Microbiol Ecol | 2024 Nov 23 | https://www.ncbi.nlm.nih.gov/pubmed/39516048 |
Modulation of sensory perception by hydrogen peroxide enables Caenorhabditis elegans to find a niche that provides both food and protection from hydrogen peroxide. | Schiffer JA, Stumbur SV, Seyedolmohadesin M, Xu Y, Serkin WT, McGowan NG, Banjo O, Torkashvand M, Lin A, Hosea CN, Assié A, Samuel BS, O'Donnell MP, Venkatachalam V, Apfeld J | PLoS pathogens | 34941962 | PLoS Pathog | 2021 Dec | https://www.ncbi.nlm.nih.gov/pubmed/34941962 |
Skin-penetrating nematodes exhibit life-stage-specific interactions with host-associated and environmental bacteria. | Chavez IN, Brown TM, Assié A, Bryant AS, Samuel BS, Hallem EA | BMC biology | 34620172 | BMC Biol | 2021 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/34620172 |
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Bidirectional modulation of anxiety-related and social behaviors by amygdala projections to the medial prefrontal cortex. | Felix-Ortiz AC, Burgos-Robles A, Bhagat ND, Leppla CA, Tye KM | Neuroscience | 26204817 | Neuroscience | 2016 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/26204817 |
Decoding neural circuits that control compulsive sucrose seeking. | Nieh EH, Matthews GA, Allsop SA, Presbrey KN, Leppla CA, Wichmann R, Neve R, Wildes CP, Tye KM | Cell | 25635460 | Cell | 2015 Jan 29 | https://www.ncbi.nlm.nih.gov/pubmed/25635460 |
In vivo optogenetic stimulation of the rodent central nervous system. | Sidor MM, Davidson TJ, Tye KM, Warden MR, Diesseroth K, McClung CA | Journal of visualized experiments : JoVE | 25651158 | J Vis Exp | 2015 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/25651158 |
Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment. | Burgos-Robles A, Kimchi EY, Izadmehr EM, Porzenheim MJ, Ramos-Guasp WA, Nieh EH, Felix-Ortiz AC, Namburi P, Leppla CA, Presbrey KN, Anandalingam KK, Pagan-Rivera PA, Anahtar M, Beyeler A, Tye KM | Nature neuroscience | 28436980 | Nat Neurosci | 2017 Jun | https://www.ncbi.nlm.nih.gov/pubmed/28436980 |
Double threat in striatal dopamine signaling. | Siciliano CA, Mills F, Tye KM | Nature neuroscience | 30258236 | Nat Neurosci | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30258236 |
Neural mechanisms of social homeostasis. | Matthews GA, Tye KM | Annals of the New York Academy of Sciences | 30875095 | Ann N Y Acad Sci | 2019 Dec | https://www.ncbi.nlm.nih.gov/pubmed/30875095 |
Dopamine enhances signal-to-noise ratio in cortical-brainstem encoding of aversive stimuli. | Vander Weele CM, Siciliano CA, Matthews GA, Namburi P, Izadmehr EM, Espinel IC, Nieh EH, Schut EHS, Padilla-Coreano N, Burgos-Robles A, Chang CJ, Kimchi EY, Beyeler A, Wichmann R, Wildes CP, Tye KM | Nature | 30405240 | Nature | 2018 Nov | https://www.ncbi.nlm.nih.gov/pubmed/30405240 |
PTEN knockdown alters dendritic spine/protrusion morphology, not density. | Haws ME, Jaramillo TC, Espinosa F, Widman AJ, Stuber GD, Sparta DR, Tye KM, Russo SJ, Parada LF, Stavarache M, Kaplitt M, Bonci A, Powell CM | The Journal of comparative neurology | 24264880 | J Comp Neurol | 2014 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/24264880 |
Amygdala inputs to the ventral hippocampus bidirectionally modulate social behavior. | Felix-Ortiz AC, Tye KM | The Journal of neuroscience : the official journal of the Society for Neuroscience | 24403157 | J Neurosci | 2014 Jan 8 | https://www.ncbi.nlm.nih.gov/pubmed/24403157 |
Dorsal Raphe Dopamine Neurons Represent the Experience of Social Isolation. | Matthews GA, Nieh EH, Vander Weele CM, Halbert SA, Pradhan RV, Yosafat AS, Glober GF, Izadmehr EM, Thomas RE, Lacy GD, Wildes CP, Ungless MA, Tye KM | Cell | 26871628 | Cell | 2016 Feb 11 | https://www.ncbi.nlm.nih.gov/pubmed/26871628 |
Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning. | Allsop SA, Wichmann R, Mills F, Burgos-Robles A, Chang CJ, Felix-Ortiz AC, Vienne A, Beyeler A, Izadmehr EM, Glober G, Cum MI, Stergiadou J, Anandalingam KK, Farris K, Namburi P, Leppla CA, Weddington JC, Nieh EH, Smith AC, Ba D, Brown EN, Tye KM | Cell | 29731170 | Cell | 2018 May 31 | https://www.ncbi.nlm.nih.gov/pubmed/29731170 |
Neural circuit reprogramming: a new paradigm for treating neuropsychiatric disease? | Tye KM | Neuron | 25233309 | Neuron | 2014 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/25233309 |
Divergent Routing of Positive and Negative Information from the Amygdala during Memory Retrieval. | Beyeler A, Namburi P, Glober GF, Simonnet C, Calhoon GG, Conyers GF, Luck R, Wildes CP, Tye KM | Neuron | 27041499 | Neuron | 2016 Apr 20 | https://www.ncbi.nlm.nih.gov/pubmed/27041499 |
Neurotensin orchestrates valence assignment in the amygdala. | Li H, Namburi P, Olson JM, Borio M, Lemieux ME, Beyeler A, Calhoon GG, Hitora-Imamura N, Coley AA, Libster A, Bal A, Jin X, Wang H, Jia C, Choudhury SR, Shi X, Felix-Ortiz AC, de la Fuente V, Barth VP, King HO, Izadmehr EM, Revanna JS, Batra K, Fischer KB, Keyes LR, Padilla-Coreano N, Siciliano CA, McCullough KM, Wichmann R, Ressler KJ, Fiete IR, Zhang F, Li Y, Tye KM | Nature | 35859170 | Nature | 2022 Aug | https://www.ncbi.nlm.nih.gov/pubmed/35859170 |
The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation. | Lee CR, Chen A, Tye KM | Cell | 33691140 | Cell | 2021 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/33691140 |
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Rapid strengthening of thalamo-amygdala synapses mediates cue-reward learning. | Tye KM, Stuber GD, de Ridder B, Bonci A, Janak PH | Nature | 18469802 | Nature | 2008 Jun 26 | https://www.ncbi.nlm.nih.gov/pubmed/18469802 |
Architectural Representation of Valence in the Limbic System. | Namburi P, Al-Hasani R, Calhoon GG, Bruchas MR, Tye KM | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 26647973 | Neuropsychopharmacology | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/26647973 |
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Leveraging calcium imaging to illuminate circuit dysfunction in addiction. | Siciliano CA, Tye KM | Alcohol (Fayetteville, N.Y.) | 30470589 | Alcohol | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30470589 |
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BLA to vHPC inputs modulate anxiety-related behaviors. | Felix-Ortiz AC, Beyeler A, Seo C, Leppla CA, Wildes CP, Tye KM | Neuron | 23972595 | Neuron | 2013 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/23972595 |
A circuit mechanism for differentiating positive and negative associations. | Namburi P, Beyeler A, Yorozu S, Calhoon GG, Halbert SA, Wichmann R, Holden SS, Mertens KL, Anahtar M, Felix-Ortiz AC, Wickersham IR, Gray JM, Tye KM | Nature | 25925480 | Nature | 2015 Apr 30 | https://www.ncbi.nlm.nih.gov/pubmed/25925480 |
A cortical-brainstem circuit predicts and governs compulsive alcohol drinking. | Siciliano CA, Noamany H, Chang CJ, Brown AR, Chen X, Leible D, Lee JJ, Wang J, Vernon AN, Vander Weele CM, Kimchi EY, Heiman M, Tye KM | Science (New York, N.Y.) | 31754002 | Science | 2019 Nov 22 | https://www.ncbi.nlm.nih.gov/pubmed/31754002 |
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Inhibitory Input from the Lateral Hypothalamus to the Ventral Tegmental Area Disinhibits Dopamine Neurons and Promotes Behavioral Activation. | Nieh EH, Vander Weele CM, Matthews GA, Presbrey KN, Wichmann R, Leppla CA, Izadmehr EM, Tye KM | Neuron | 27238864 | Neuron | 2016 Jun 15 | https://www.ncbi.nlm.nih.gov/pubmed/27238864 |
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High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels. | Berndt A, Schoenenberger P, Mattis J, Tye KM, Deisseroth K, Hegemann P, Oertner TG | Proceedings of the National Academy of Sciences of the United States of America | 21504945 | Proc Natl Acad Sci U S A | 2011 May 3 | https://www.ncbi.nlm.nih.gov/pubmed/21504945 |
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Dopamine neurons modulate neural encoding and expression of depression-related behaviour. | Tye KM, Mirzabekov JJ, Warden MR, Ferenczi EA, Tsai HC, Finkelstein J, Kim SY, Adhikari A, Thompson KR, Andalman AS, Gunaydin LA, Witten IB, Deisseroth K | Nature | 23235822 | Nature | 2013 Jan 24 | https://www.ncbi.nlm.nih.gov/pubmed/23235822 |
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Natural neural projection dynamics underlying social behavior. | Gunaydin LA, Grosenick L, Finkelstein JC, Kauvar IV, Fenno LE, Adhikari A, Lammel S, Mirzabekov JJ, Airan RD, Zalocusky KA, Tye KM, Anikeeva P, Malenka RC, Deisseroth K | Cell | 24949967 | Cell | 2014 Jun 19 | https://www.ncbi.nlm.nih.gov/pubmed/24949967 |
A light- and calcium-gated transcription factor for imaging and manipulating activated neurons. | Wang W, Wildes CP, Pattarabanjird T, Sanchez MI, Glober GF, Matthews GA, Tye KM, Ting AY | Nature biotechnology | 28650461 | Nat Biotechnol | 2017 Sep | https://www.ncbi.nlm.nih.gov/pubmed/28650461 |
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From circuits to behaviour in the amygdala. | Janak PH, Tye KM | Nature | 25592533 | Nature | 2015 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/25592533 |
Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. | Stuber GD, Sparta DR, Stamatakis AM, van Leeuwen WA, Hardjoprajitno JE, Cho S, Tye KM, Kempadoo KA, Zhang F, Deisseroth K, Bonci A | Nature | 21716290 | Nature | 2011 Jun 29 | https://www.ncbi.nlm.nih.gov/pubmed/21716290 |
Organization of Valence-Encoding and Projection-Defined Neurons in the Basolateral Amygdala. | Beyeler A, Chang CJ, Silvestre M, Lévêque C, Namburi P, Wildes CP, Tye KM | Cell reports | 29386133 | Cell Rep | 2018 Jan 23 | https://www.ncbi.nlm.nih.gov/pubmed/29386133 |
Reward contingency gates selective cholinergic suppression of amygdala neurons. | Kimchi EY, Burgos-Robles A, Matthews GA, Chakoma T, Patarino M, Weddington JC, Siciliano C, Yang W, Foutch S, Simons R, Fong MF, Jing M, Li Y, Polley DB, Tye KM | eLife | 38376907 | Elife | 2024 Feb 20 | https://www.ncbi.nlm.nih.gov/pubmed/38376907 |
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. | Shi ZD, Lee K, Yang D, Amin S, Verma N, Li QV, Zhu Z, Soh CL, Kumar R, Evans T, Chen S, Huangfu D | Cell stem cell | 28196600 | Cell Stem Cell | 2017 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/28196600 |
ROCKII inhibition promotes the maturation of human pancreatic beta-like cells. | Ghazizadeh Z, Kao DI, Amin S, Cook B, Rao S, Zhou T, Zhang T, Xiang Z, Kenyon R, Kaymakcalan O, Liu C, Evans T, Chen S | Nature communications | 28824164 | Nat Commun | 2017 Aug 21 | https://www.ncbi.nlm.nih.gov/pubmed/28824164 |
Multifunctional in vivo imaging of pancreatic islets during diabetes development. | Li G, Wu B, Ward MG, Chong AC, Mukherjee S, Chen S, Hao M | Journal of cell science | 27270669 | J Cell Sci | 2016 Jul 15 | https://www.ncbi.nlm.nih.gov/pubmed/27270669 |
Modeling Cystic Fibrosis Using Pluripotent Stem Cell-Derived Human Pancreatic Ductal Epithelial Cells. | Simsek S, Zhou T, Robinson CL, Tsai SY, Crespo M, Amin S, Lin X, Hon J, Evans T, Chen S | Stem cells translational medicine | 27034411 | Stem Cells Transl Med | 2016 May | https://www.ncbi.nlm.nih.gov/pubmed/27034411 |
Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. | Fattahi F, Steinbeck JA, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, Zeltner N, Mica Y, El-Nachef W, Zhao H, de Stanchina E, Gershon MD, Grikscheit TC, Chen S, Studer L | Nature | 26863197 | Nature | 2016 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/26863197 |
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. | Crespo M, Vilar E, Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, Chen S | Nature medicine | 28628110 | Nat Med | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28628110 |
Endothelial cells control pancreatic cell fate at defined stages through EGFL7 signaling. | Kao DI, Lacko LA, Ding BS, Huang C, Phung K, Gu G, Rafii S, Stuhlmann H, Chen S | Stem cell reports | 25601205 | Stem Cell Reports | 2015 Feb 10 | https://www.ncbi.nlm.nih.gov/pubmed/25601205 |
Discovery of a Small-Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation. | Feng L, Cook B, Tsai SY, Zhou T, LaFlamme B, Evans T, Chen S | Cell reports | 27210748 | Cell Rep | 2016 May 31 | https://www.ncbi.nlm.nih.gov/pubmed/27210748 |
High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain. | Zhou T, Tan L, Cederquist GY, Fan Y, Hartley BJ, Mukherjee S, Tomishima M, Brennand KJ, Zhang Q, Schwartz RE, Evans T, Studer L, Chen S | Cell stem cell | 28736217 | Cell Stem Cell | 2017 Aug 3 | https://www.ncbi.nlm.nih.gov/pubmed/28736217 |
The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy. | Kim RS, Hasegawa D, Goossens N, Tsuchida T, Athwal V, Sun X, Robinson CL, Bhattacharya D, Chou HI, Zhang DY, Fuchs BC, Lee Y, Hoshida Y, Friedman SL | Scientific reports | 27996033 | Sci Rep | 2016 Dec 20 | https://www.ncbi.nlm.nih.gov/pubmed/27996033 |
An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis. | Walsh LA, Alvarez MJ, Sabio EY, Reyngold M, Makarov V, Mukherjee S, Lee KW, Desrichard A, Turcan Ş, Dalin MG, Rajasekhar VK, Chen S, Vahdat LT, Califano A, Chan TA | Cell reports | 28813674 | Cell Rep | 2017 Aug 15 | https://www.ncbi.nlm.nih.gov/pubmed/28813674 |
Nanofibrous microposts and microwells of controlled shapes and their hybridization with hydrogels for cell encapsulation. | Song W, An D, Kao DI, Lu YC, Dai G, Chen S, Ma M | ACS applied materials & interfaces | 24806031 | ACS Appl Mater Interfaces | 2014 May 28 | https://www.ncbi.nlm.nih.gov/pubmed/24806031 |
Pluripotent stem cell-derived pancreatic β-cells: potential for regenerative medicine in diabetes. | Kao DI, Chen S | Regenerative medicine | 22817630 | Regen Med | 2012 Jul | https://www.ncbi.nlm.nih.gov/pubmed/22817630 |
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival. | Zhou T, Kim TW, Chong CN, Tan L, Amin S, Sadat Badieyan Z, Mukherjee S, Ghazizadeh Z, Zeng H, Guo M, Crespo M, Zhang T, Kenyon R, Robinson CL, Apostolou E, Wang H, Xiang JZ, Evans T, Studer L, Chen S | Nature communications | 30446643 | Nat Commun | 2018 Nov 16 | https://www.ncbi.nlm.nih.gov/pubmed/30446643 |
Identification of Annexin A4 as a hepatopancreas factor involved in liver cell survival. | Zhang D, Golubkov VS, Han W, Correa RG, Zhou Y, Lee S, Strongin AY, Dong PD | Developmental biology | 25176043 | Dev Biol | 2014 Nov 1 | https://www.ncbi.nlm.nih.gov/pubmed/25176043 |
Lineage analysis reveals an endodermal contribution to the vertebrate pituitary. | Fabian P, Tseng KC, Smeeton J, Lancman JJ, Dong PDS, Cerny R, Crump JG | Science (New York, N.Y.) | 33093109 | Science | 2020 Oct 23 | https://www.ncbi.nlm.nih.gov/pubmed/33093109 |
Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. | Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDS, Gaulton KJ, Sander M | eLife | 33544077 | Elife | 2021 Feb 5 | https://www.ncbi.nlm.nih.gov/pubmed/33544077 |
Intrahepatic cholangiocyte regeneration from an Fgf-dependent extrahepatic progenitor niche in a zebrafish model of Alagille Syndrome. | Zhao C, Lancman JJ, Yang Y, Gates KP, Cao D, Barske L, Matalonga J, Pan X, He J, Graves A, Huisken J, Chen C, Dong PDS | Hepatology (Baltimore, Md.) | 34569629 | Hepatology | 2022 Mar | https://www.ncbi.nlm.nih.gov/pubmed/34569629 |
Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling. | Zhao C, Matalonga J, Lancman JJ, Liu L, Xiao C, Kumar S, Gates KP, He J, Graves A, Huisken J, Azuma M, Lu Z, Chen C, Ding BS, Dong PDS | Proceedings of the National Academy of Sciences of the United States of America | 36469766 | Proc Natl Acad Sci U S A | 2022 Dec 13 | https://www.ncbi.nlm.nih.gov/pubmed/36469766 |
Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb. | Lancman JJ, Zvenigorodsky N, Gates KP, Zhang D, Solomon K, Humphrey RK, Kuo T, Setiawan L, Verkade H, Chi YI, Jhala US, Wright CV, Stainier DY, Dong PD | Development (Cambridge, England) | 23720049 | Development | 2013 Jul | https://www.ncbi.nlm.nih.gov/pubmed/23720049 |
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Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. | Hockman D, Burns AJ, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PDS, Lickert H, Tucker AS, Baker CV | eLife | 28387645 | Elife | 2017 Apr 7 | https://www.ncbi.nlm.nih.gov/pubmed/28387645 |
Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia. | Liu C, Gates KP, Fang L, Amar MJ, Schneider DA, Geng H, Huang W, Kim J, Pattison J, Zhang J, Witztum JL, Remaley AT, Dong PD, Miller YI | Disease models & mechanisms | 26044956 | Dis Model Mech | 2015 Aug 1 | https://www.ncbi.nlm.nih.gov/pubmed/26044956 |
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Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness. | Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, Wu JC, Moon RT, Si Dong PD, Karakikes I, Cashman JR, Mercola M | Cell chemical biology | 33503403 | Cell Chem Biol | 2021 May 20 | https://www.ncbi.nlm.nih.gov/pubmed/33503403 |
KPC and NDM-1 genes in related Enterobacteriaceae strains and plasmids from Pakistan and the United States. | Pesesky MW, Hussain T, Wallace M, Wang B, Andleeb S, Burnham CA, Dantas G | Emerging infectious diseases | 25988236 | Emerg Infect Dis | 2015 Jun | https://www.ncbi.nlm.nih.gov/pubmed/25988236 |
Functional Metagenomics to Study Antibiotic Resistance. | Boolchandani M, Patel S, Dantas G | Methods in molecular biology (Clifton, N.J.) | 27873261 | Methods Mol Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/27873261 |
Characterization of Wild and Captive Baboon Gut Microbiota and Their Antibiotic Resistomes. | Tsukayama P, Boolchandani M, Patel S, Pehrsson EC, Gibson MK, Chiou KL, Jolly CJ, Rogers J, Phillips-Conroy JE, Dantas G | mSystems | 29963641 | mSystems | 2018 May-Jun | https://www.ncbi.nlm.nih.gov/pubmed/29963641 |
Longitudinal analysis of microbial interaction between humans and the indoor environment. | Lax S, Smith DP, Hampton-Marcell J, Owens SM, Handley KM, Scott NM, Gibbons SM, Larsen P, Shogan BD, Weiss S, Metcalf JL, Ursell LK, Vázquez-Baeza Y, Van Treuren W, Hasan NA, Gibson MK, Colwell R, Dantas G, Knight R, Gilbert JA | Science (New York, N.Y.) | 25170151 | Science | 2014 Aug 29 | https://www.ncbi.nlm.nih.gov/pubmed/25170151 |
Bacterial phylogeny structures soil resistomes across habitats. | Forsberg KJ, Patel S, Gibson MK, Lauber CL, Knight R, Fierer N, Dantas G | Nature | 24847883 | Nature | 2014 May 29 | https://www.ncbi.nlm.nih.gov/pubmed/24847883 |
Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms. | Sun J, Liao XP, D'Souza AW, Boolchandani M, Li SH, Cheng K, Luis Martínez J, Li L, Feng YJ, Fang LX, Huang T, Xia J, Yu Y, Zhou YF, Sun YX, Deng XB, Zeng ZL, Jiang HX, Fang BH, Tang YZ, Lian XL, Zhang RM, Fang ZW, Yan QL, Dantas G, Liu YH | Nature communications | 32188862 | Nat Commun | 2020 Mar 18 | https://www.ncbi.nlm.nih.gov/pubmed/32188862 |
Prairie plants harbor distinct and beneficial root-endophytic bacterial communities. | Adu-Oppong B, Mangan SA, Stein C, Catano CP, Myers JA, Dantas G | PloS one | 32574172 | PLoS One | 2020 | https://www.ncbi.nlm.nih.gov/pubmed/32574172 |
Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes. | Adu-Oppong B, Gasparrini AJ, Dantas G | Annals of the New York Academy of Sciences | 27768825 | Ann N Y Acad Sci | 2017 Jan | https://www.ncbi.nlm.nih.gov/pubmed/27768825 |
The microbiome and resistome of chimpanzees, gorillas, and humans across host lifestyle and geography. | Campbell TP, Sun X, Patel VH, Sanz C, Morgan D, Dantas G | The ISME journal | 32203121 | ISME J | 2020 Jun | https://www.ncbi.nlm.nih.gov/pubmed/32203121 |
The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes. | Forsberg KJ, Patel S, Wencewicz TA, Dantas G | Chemistry & biology | 26097034 | Chem Biol | 2015 Jul 23 | https://www.ncbi.nlm.nih.gov/pubmed/26097034 |
Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria. | Crofts TS, Wang B, Spivak A, Gianoulis TA, Forsberg KJ, Gibson MK, Johnsky LA, Broomall SM, Rosenzweig CN, Skowronski EW, Gibbons HS, Sommer MOA, Dantas G | Genome announcements | 28798166 | Genome Announc | 2017 Aug 10 | https://www.ncbi.nlm.nih.gov/pubmed/28798166 |
Functional mining of novel terpene synthases from metagenomes. | Kwak S, Crook N, Yoneda A, Ahn N, Ning J, Cheng J, Dantas G | Biotechnology for biofuels and bioproducts | 36209178 | Biotechnol Biofuels Bioprod | 2022 Oct 8 | https://www.ncbi.nlm.nih.gov/pubmed/36209178 |
Improved annotation of antibiotic resistance determinants reveals microbial resistomes cluster by ecology. | Gibson MK, Forsberg KJ, Dantas G | The ISME journal | 25003965 | ISME J | 2015 Jan | https://www.ncbi.nlm.nih.gov/pubmed/25003965 |
The yin and yang of bacterial resilience in the human gut microbiota. | Gibson MK, Pesesky MW, Dantas G | Journal of molecular biology | 24911583 | J Mol Biol | 2014 Nov 25 | https://www.ncbi.nlm.nih.gov/pubmed/24911583 |
Evaluation of Machine Learning and Rules-Based Approaches for Predicting Antimicrobial Resistance Profiles in Gram-negative Bacilli from Whole Genome Sequence Data. | Pesesky MW, Hussain T, Wallace M, Patel S, Andleeb S, Burnham CD, Dantas G | Frontiers in microbiology | 27965630 | Front Microbiol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/27965630 |
The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation. | Langdon A, Crook N, Dantas G | Genome medicine | 27074706 | Genome Med | 2016 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/27074706 |
Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut. | Crook N, Ferreiro A, Gasparrini AJ, Pesesky MW, Gibson MK, Wang B, Sun X, Condiotte Z, Dobrowolski S, Peterson D, Dantas G | Cell host & microbe | 30926240 | Cell Host Microbe | 2019 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/30926240 |
Discovery and Characterization of a Nitroreductase Capable of Conferring Bacterial Resistance to Chloramphenicol. | Crofts TS, Sontha P, King AO, Wang B, Biddy BA, Zanolli N, Gaumnitz J, Dantas G | Cell chemical biology | 30799223 | Cell Chem Biol | 2019 Apr 18 | https://www.ncbi.nlm.nih.gov/pubmed/30799223 |
The microbiome of uncontacted Amerindians. | Clemente JC, Pehrsson EC, Blaser MJ, Sandhu K, Gao Z, Wang B, Magris M, Hidalgo G, Contreras M, Noya-Alarcón Ó, Lander O, McDonald J, Cox M, Walter J, Oh PL, Ruiz JF, Rodriguez S, Shen N, Song SJ, Metcalf J, Knight R, Dantas G, Dominguez-Bello MG | Science advances | 26229982 | Sci Adv | 2015 Apr 3 | https://www.ncbi.nlm.nih.gov/pubmed/26229982 |
Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs. | Pehrsson EC, Forsberg KJ, Gibson MK, Ahmadi S, Dantas G | Frontiers in microbiology | 23760651 | Front Microbiol | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23760651 |
High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED. | Kaminski J, Gibson MK, Franzosa EA, Segata N, Dantas G, Huttenhower C | PLoS computational biology | 26682918 | PLoS Comput Biol | 2015 Dec | https://www.ncbi.nlm.nih.gov/pubmed/26682918 |
Identification of Genes Conferring Tolerance to Lignocellulose-Derived Inhibitors by Functional Selections in Soil Metagenomes. | Forsberg KJ, Patel S, Witt E, Wang B, Ellison TD, Dantas G | Applied and environmental microbiology | 26546427 | Appl Environ Microbiol | 2016 Jan 15 | https://www.ncbi.nlm.nih.gov/pubmed/26546427 |
Next-generation approaches to understand and combat the antibiotic resistome. | Crofts TS, Gasparrini AJ, Dantas G | Nature reviews. Microbiology | 28392565 | Nat Rev Microbiol | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28392565 |
Functional Metagenomics to Study Antibiotic Resistance. | Mahmud B, Boolchandani M, Patel S, Dantas G | Methods in molecular biology (Clifton, N.J.) | 36445596 | Methods Mol Biol | 2023 | https://www.ncbi.nlm.nih.gov/pubmed/36445596 |
Shared strategies for β-lactam catabolism in the soil microbiome. | Crofts TS, Wang B, Spivak A, Gianoulis TA, Forsberg KJ, Gibson MK, Johnsky LA, Broomall SM, Rosenzweig CN, Skowronski EW, Gibbons HS, Sommer MOA, Dantas G | Nature chemical biology | 29713061 | Nat Chem Biol | 2018 Jun | https://www.ncbi.nlm.nih.gov/pubmed/29713061 |
Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in E. coli Nissle Residing in the Mammalian Gut. | Crook N, Ferreiro A, Condiotte Z, Dantas G | ACS synthetic biology | 32324995 | ACS Synth Biol | 2020 May 15 | https://www.ncbi.nlm.nih.gov/pubmed/32324995 |
Antibiotics and the developing infant gut microbiota and resistome. | Gibson MK, Crofts TS, Dantas G | Current opinion in microbiology | 26241507 | Curr Opin Microbiol | 2015 Oct | https://www.ncbi.nlm.nih.gov/pubmed/26241507 |
Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA. | Gonzales PR, Pesesky MW, Bouley R, Ballard A, Biddy BA, Suckow MA, Wolter WR, Schroeder VA, Burnham CA, Mobashery S, Chang M, Dantas G | Nature chemical biology | 26368589 | Nat Chem Biol | 2015 Nov | https://www.ncbi.nlm.nih.gov/pubmed/26368589 |
Single-cell measurement of red blood cell oxygen affinity. | Di Caprio G, Stokes C, Higgins JM, Schonbrun E | Proceedings of the National Academy of Sciences of the United States of America | 26216973 | Proc Natl Acad Sci U S A | 2015 Aug 11 | https://www.ncbi.nlm.nih.gov/pubmed/26216973 |
Developmental plasticity of red blood cell homeostasis. | Golub MS, Hogrefe CE, Malka R, Higgins JM | American journal of hematology | 24415575 | Am J Hematol | 2014 May | https://www.ncbi.nlm.nih.gov/pubmed/24415575 |
Data-driven physiologic thresholds for iron deficiency associated with hematologic decline. | Foy BH, Li A, McClung JP, Ranganath R, Higgins JM | American journal of hematology | 31849101 | Am J Hematol | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31849101 |
Non-Parametric Combined Reference Regions and Prediction of Clinical Risk. | Malka R, Brugnara C, Cialic R, Higgins JM | Clinical chemistry | 32040586 | Clin Chem | 2020 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/32040586 |
Hereditary xerocytosis revisited. | Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG | American journal of hematology | 25044010 | Am J Hematol | 2014 Dec | https://www.ncbi.nlm.nih.gov/pubmed/25044010 |
Red blood cell population dynamics. | Higgins JM | Clinics in laboratory medicine | 25676371 | Clin Lab Med | 2015 Mar | https://www.ncbi.nlm.nih.gov/pubmed/25676371 |
White Blood Cell and Platelet Dynamics Define Human Inflammatory Recovery. | Foy BH, Sundt T, Carlson JCT, Aguirre AD, Higgins JM | medRxiv : the preprint server for health sciences | 34189534 | medRxiv | 2021 Jun 23 | https://www.ncbi.nlm.nih.gov/pubmed/34189534 |
A microfluidic platform to study the effects of vascular architecture and oxygen gradients on sickle blood flow. | Lu X, Galarneau MM, Higgins JM, Wood DK | Microcirculation (New York, N.Y. : 1994) | 28129479 | Microcirculation | 2017 Jul | https://www.ncbi.nlm.nih.gov/pubmed/28129479 |
Intracellular water exchange for measuring the dry mass, water mass and changes in chemical composition of living cells. | Feijó Delgado F, Cermak N, Hecht VC, Son S, Li Y, Knudsen SM, Olcum S, Higgins JM, Chen J, Grover WH, Manalis SR | PloS one | 23844039 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23844039 |
Age-related clonal hematopoiesis associated with adverse outcomes. | Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, Kinnunen L, Koistinen HA, Ladenvall C, Getz G, Correa A, Banahan BF, Gabriel S, Kathiresan S, Stringham HM, McCarthy MI, Boehnke M, Tuomilehto J, Haiman C, Groop L, Atzmon G, Wilson JG, Neuberg D, Altshuler D, Ebert BL | The New England journal of medicine | 25426837 | N Engl J Med | 2014 Dec 25 | https://www.ncbi.nlm.nih.gov/pubmed/25426837 |
Modulation of red blood cell population dynamics is a fundamental homeostatic response to disease. | Patel HH, Patel HR, Higgins JM | American journal of hematology | 25691355 | Am J Hematol | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25691355 |
In vivo volume and hemoglobin dynamics of human red blood cells. | Malka R, Delgado FF, Manalis SR, Higgins JM | PLoS computational biology | 25299941 | PLoS Comput Biol | 2014 Oct | https://www.ncbi.nlm.nih.gov/pubmed/25299941 |
5-(Hydroxymethyl)furfural restores low-oxygen rheology of sickle trait blood in vitro. | Hansen S, Wood DK, Higgins JM | British journal of haematology | 31889311 | Br J Haematol | 2020 Mar | https://www.ncbi.nlm.nih.gov/pubmed/31889311 |
Human acute inflammatory recovery is defined by co-regulatory dynamics of white blood cell and platelet populations. | Foy BH, Sundt TM, Carlson JCT, Aguirre AD, Higgins JM | Nature communications | 35995789 | Nat Commun | 2022 Aug 22 | https://www.ncbi.nlm.nih.gov/pubmed/35995789 |
Quantitative absorption cytometry for measuring red blood cell hemoglobin mass and volume. | Schonbrun E, Malka R, Di Caprio G, Schaak D, Higgins JM | Cytometry. Part A : the journal of the International Society for Analytical Cytology | 24677669 | Cytometry A | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24677669 |
Mechanistic modeling of hemoglobin glycation and red blood cell kinetics enables personalized diabetes monitoring. | Malka R, Nathan DM, Higgins JM | Science translational medicine | 27708063 | Sci Transl Med | 2016 Oct 5 | https://www.ncbi.nlm.nih.gov/pubmed/27708063 |
Oxygen-dependent flow of sickle trait blood as an in vitro therapeutic benchmark for sickle cell disease treatments. | Lu X, Chaudhury A, Higgins JM, Wood DK | American journal of hematology | 30033564 | Am J Hematol | 2018 Oct | https://www.ncbi.nlm.nih.gov/pubmed/30033564 |
Determinants of red blood cell alloantibody detection duration: analysis of multiply alloimmunized patients supports peritransfusion factors. | Noiret L, Slater A, Higgins JM | Transfusion | 28639314 | Transfusion | 2017 Aug | https://www.ncbi.nlm.nih.gov/pubmed/28639314 |
Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension. | Lu X, Wood DK, Higgins JM | Biophysical journal | 27332133 | Biophys J | 2016 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/27332133 |
White blood cell population dynamics for risk stratification of acute coronary syndrome. | Chaudhury A, Noiret L, Higgins JM | Proceedings of the National Academy of Sciences of the United States of America | 29087321 | Proc Natl Acad Sci U S A | 2017 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/29087321 |
Dynamic cell fate plasticity and tissue integration drive functional synovial joint regeneration. | Blumenkrantz M, Woron F, Gagarin E, Weinstein E, Kamel MH, Campos L, Geras A, Anderson T, Mo J, Sherwood D, Gwin M, Dumitrascu B, Chahine NO, Smeeton J | bioRxiv : the preprint server for biology | 39713398 | bioRxiv | 2024 Dec 12 | https://www.ncbi.nlm.nih.gov/pubmed/39713398 |
Toward a Wireless Image Sensor for Real-Time Fluorescence Microscopy in Cancer Therapy. | Rabbani R, Najafiaghdam H, Roschelle M, Papageorgiou EP, Zhao BR, Ghanbari MM, Muller R, Stojanovic V, Anwar M | IEEE transactions on biomedical circuits and systems | 38457321 | IEEE Trans Biomed Circuits Syst | 2024 Oct | https://www.ncbi.nlm.nih.gov/pubmed/38457321 |
Fully Integrated Ultra-thin Intraoperative Micro-imager for Cancer Detection Using Upconverting Nanoparticles. | Najafiaghdam H, Pedroso CCS, Torquato NA, Cohen BE, Anwar M | Molecular imaging and biology | 35312938 | Mol Imaging Biol | 2023 Feb | https://www.ncbi.nlm.nih.gov/pubmed/35312938 |
3D Reconstruction of cellular images from microfabricated imagers using fully-adaptive deep neural networks. | Najafiaghdam H, Rabbani R, Gharia A, Papageorgiou EP, Anwar M | Scientific reports | 35508477 | Sci Rep | 2022 May 4 | https://www.ncbi.nlm.nih.gov/pubmed/35508477 |
Optics-Free Chip-Scale Intraoperative Imaging Using NIR-Excited Upconverting Nanoparticles. | Najafiaghdam H, Pedroso CCS, Cohen BE, Anwar M | IEEE transactions on biomedical circuits and systems | 35385388 | IEEE Trans Biomed Circuits Syst | 2022 Apr | https://www.ncbi.nlm.nih.gov/pubmed/35385388 |
Microfluidic Packaging Integration with Electronic-Photonic Biosensors Using 3D Printed Transfer Molding. | Adamopoulos C, Gharia A, Niknejad A, Stojanović V, Anwar M | Biosensors | 33202594 | Biosensors (Basel) | 2020 Nov 14 | https://www.ncbi.nlm.nih.gov/pubmed/33202594 |
A Wireless, Multicolor Fluorescence Image Sensor Implant for Real-Time Monitoring in Cancer Therapy. | Roschelle M, Rabbani R, Gweon S, Kumar R, Vercruysse A, Cho NW, Spitzer MH, Niknejad AM, Stojanović VM, Anwar M | ArXiv | 38979489 | ArXiv | 2024 Jun 27 | https://www.ncbi.nlm.nih.gov/pubmed/38979489 |
Towards A Wireless Image Sensor for Real-Time Fluorescence Microscopy in Cancer Therapy. | Rabbani R, Najafiaghdam H, Roschelle M, Papageorgiou EP, Zhao BR, Ghanbari MM, Muller R, Stojanovic V, Anwar M | bioRxiv : the preprint server for biology | 38106190 | bioRxiv | 2023 Dec 5 | https://www.ncbi.nlm.nih.gov/pubmed/38106190 |
Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration. | Bonar NA, Petersen CP | Development (Cambridge, England) | 28126842 | Development | 2017 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/28126842 |
Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration. | Lander R, Petersen CP | eLife | 27074666 | Elife | 2016 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/27074666 |
Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for animal nociception. | Arenas OM, Zaharieva EE, Para A, Vásquez-Doorman C, Petersen CP, Gallio M | Nature neuroscience | 29184198 | Nat Neurosci | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/29184198 |
Positional information specifies the site of organ regeneration and not tissue maintenance in planarians. | Hill EM, Petersen CP | eLife | 29547123 | Elife | 2018 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/29547123 |
zic-1 Expression in Planarian neoblasts after injury controls anterior pole regeneration. | Vásquez-Doorman C, Petersen CP | PLoS genetics | 24992682 | PLoS Genet | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/24992682 |
Wnt/Notum spatial feedback inhibition controls neoblast differentiation to regulate reversible growth of the planarian brain. | Hill EM, Petersen CP | Development (Cambridge, England) | 26525673 | Development | 2015 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/26525673 |
The NuRD complex component p66 suppresses photoreceptor neuron regeneration in planarians. | Vásquez-Doorman C, Petersen CP | Regeneration (Oxford, England) | 27606067 | Regeneration (Oxf) | 2016 Jun | https://www.ncbi.nlm.nih.gov/pubmed/27606067 |
Controlled Human Malaria Infection Leads to Long-Lasting Changes in Innate and Innate-like Lymphocyte Populations. | Mpina M, Maurice NJ, Yajima M, Slichter CK, Miller HW, Dutta M, McElrath MJ, Stuart KD, De Rosa SC, McNevin JP, Linsley PS, Abdulla S, Tanner M, Hoffman SL, Gottardo R, Daubenberger CA, Prlic M | Journal of immunology (Baltimore, Md. : 1950) | 28576979 | J Immunol | 2017 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/28576979 |
Inflammation and TCR signal strength determine the breadth of the T cell response in a bim-dependent manner. | Zehn D, Roepke S, Weakly K, Bevan MJ, Prlic M | Journal of immunology (Baltimore, Md. : 1950) | 24273000 | J Immunol | 2014 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/24273000 |
The human tissue-resident CCR5(+) T cell compartment maintains protective and functional properties during inflammation. | Woodward Davis AS, Roozen HN, Dufort MJ, DeBerg HA, Delaney MA, Mair F, Erickson JR, Slichter CK, Berkson JD, Klock AM, Mack M, Lwo Y, Ko A, Brand RM, McGowan I, Linsley PS, Dixon DR, Prlic M | Science translational medicine | 31801887 | Sci Transl Med | 2019 Dec 4 | https://www.ncbi.nlm.nih.gov/pubmed/31801887 |
Human MAIT cells exit peripheral tissues and recirculate via lymph in steady state conditions. | Voillet V, Buggert M, Slichter CK, Berkson JD, Mair F, Addison MM, Dori Y, Nadolski G, Itkin MG, Gottardo R, Betts MR, Prlic M | JCI insight | 29618662 | JCI Insight | 2018 Apr 5 | https://www.ncbi.nlm.nih.gov/pubmed/29618662 |
The MAIT conundrum - how human MAIT cells distinguish bacterial colonization from infection in mucosal barrier tissues. | Berkson JD, Prlic M | Immunology letters | 28987476 | Immunol Lett | 2017 Dec | https://www.ncbi.nlm.nih.gov/pubmed/28987476 |
The human memory T cell compartment changes across tissues of the female reproductive tract. | Woodward Davis AS, Vick SC, Pattacini L, Voillet V, Hughes SM, Lentz GM, Kirby AC, Fialkow MF, Gottardo R, Hladik F, Lund JM, Prlic M | Mucosal immunology | 33953338 | Mucosal Immunol | 2021 Jul | https://www.ncbi.nlm.nih.gov/pubmed/33953338 |
A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire. | Oberle SG, Hanna-El-Daher L, Chennupati V, Enouz S, Scherer S, Prlic M, Zehn D | Cell reports | 27732840 | Cell Rep | 2016 Oct 11 | https://www.ncbi.nlm.nih.gov/pubmed/27732840 |
OMIP-044: 28-color immunophenotyping of the human dendritic cell compartment. | Mair F, Prlic M | Cytometry. Part A : the journal of the International Society for Analytical Cytology | 29356334 | Cytometry A | 2018 Apr | https://www.ncbi.nlm.nih.gov/pubmed/29356334 |
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4(+) T Cells in Peripheral Blood of Subjects with Type 1 Diabetes. | Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS | Journal of immunology (Baltimore, Md. : 1950) | 28566371 | J Immunol | 2017 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/28566371 |
Anti-proliferative therapy for HIV cure: a compound interest approach. | Reeves DB, Duke ER, Hughes SM, Prlic M, Hladik F, Schiffer JT | Scientific reports | 28638104 | Sci Rep | 2017 Jun 21 | https://www.ncbi.nlm.nih.gov/pubmed/28638104 |
Distinct activation thresholds of human conventional and innate-like memory T cells. | Slichter CK, McDavid A, Miller HW, Finak G, Seymour BJ, McNevin JP, Diaz G, Czartoski JL, McElrath MJ, Gottardo R, Prlic M | JCI insight | 27331143 | JCI Insight | 2016 Jun 2 | https://www.ncbi.nlm.nih.gov/pubmed/27331143 |
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data. | Finak G, McDavid A, Yajima M, Deng J, Gersuk V, Shalek AK, Slichter CK, Miller HW, McElrath MJ, Prlic M, Linsley PS, Gottardo R | Genome biology | 26653891 | Genome Biol | 2015 Dec 10 | https://www.ncbi.nlm.nih.gov/pubmed/26653891 |