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NIH Director's New Innovator  (NIA)

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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Author Journal Name PubMedID Journal Abbreviation Publication Date PubMedLink
Exploring Antibiotic Resistance in Diverse Homologs of the Dihydrofolate Reductase Protein Family through Broad Mutational Scanning. Romanowicz KJ, Resnick C, Hinton SR, Plesa C bioRxiv : the preprint server for biology 39896582 bioRxiv 2025 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/39896582
Rational Design of Nanomedicine for Placental Disorders: Birthing a New Era in Women's Reproductive Health. Geisler HC, Safford HC, Mitchell MJ Small (Weinheim an der Bergstrasse, Germany) 37191231 Small 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/37191231
Peptide functionalized liposomes for receptor targeted cancer therapy. Aronson MR, Medina SH, Mitchell MJ APL bioengineering 33532673 APL Bioeng 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33532673
An ionizable lipid toolbox for RNA delivery. Han X, Zhang H, Butowska K, Swingle KL, Alameh MG, Weissman D, Mitchell MJ Nature communications 34903741 Nat Commun 2021 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/34903741
Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Gong N, Han X, Xue L, Billingsley MM, Huang X, El-Mayta R, Qin J, Sheppard NC, June CH, Mitchell MJ Nature biomedical engineering 38378820 Nat Biomed Eng 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38378820
Lipid-mediated intracellular delivery of recombinant bioPROTACs for the rapid degradation of undruggable proteins. Chan A, Haley RM, Najar MA, Gonzalez-Martinez D, Bugaj LJ, Burslem GM, Mitchell MJ, Tsourkas A Nature communications 38987546 Nat Commun 2024 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/38987546
Flow cytometric analysis of the murine placenta to evaluate nanoparticle platforms during pregnancy. Swingle KL, Hamilton AG, Mitchell MJ Placenta 39181830 Placenta 2024 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/39181830
Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain. Nong J, Glassman PM, Myerson JW, Zuluaga-Ramirez V, Rodriguez-Garcia A, Mukalel A, Omo-Lamai S, Walsh LR, Zamora ME, Gong X, Wang Z, Bhamidipati K, Kiseleva RY, Villa CH, Greineder CF, Kasner SE, Weissman D, Mitchell MJ, Muro S, Persidsky Y, Brenner JS, Muzykantov VR, Marcos-Contreras OA ACS nano 37432926 ACS Nano 2023 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/37432926
Solution biophysics identifies lipid nanoparticle non-sphericity, polydispersity, and dependence on internal ordering for efficacious mRNA delivery. Padilla MS, Shepherd SJ, Hanna AR, Kurnik M, Zhang X, Chen M, Byrnes J, Joseph RA, Yamagata HM, Ricciardi AS, Mrksich K, Issadore D, Gupta K, Mitchell MJ bioRxiv : the preprint server for biology 39763759 bioRxiv 2025 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/39763759
Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes. Guimaraes PPG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CTR, Jacks T, Langer R, Mitchell MJ Journal of controlled release : official journal of the Controlled Release Society 30290244 J Control Release 2018 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/30290244
Chiral Supraparticles for Controllable Nanomedicine. Yeom J, Guimaraes PPG, Ahn HM, Jung BK, Hu Q, McHugh K, Mitchell MJ, Yun CO, Langer R, Jaklenec A Advanced materials (Deerfield Beach, Fla.) 31686433 Adv Mater 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31686433
Ionizable lipid nanoparticles for in utero mRNA delivery. Riley RS, Kashyap MV, Billingsley MM, White B, Alameh MG, Bose SK, Zoltick PW, Li H, Zhang R, Cheng AY, Weissman D, Peranteau WH, Mitchell MJ Science advances 33523869 Sci Adv 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33523869
Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver. Zhang R , El-Mayta R , Murdoch TJ , Warzecha CC , Billingsley MM , Shepherd SJ , Gong N , Wang L , Wilson JM , Lee D , Mitchell MJ Biomaterials science 33404020 Biomater Sci 2021 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/33404020
Nanomaterials for T-cell cancer immunotherapy. Gong N, Sheppard NC, Billingsley MM, June CH, Mitchell MJ Nature nanotechnology 33437036 Nat Nanotechnol 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33437036
Engineering precision nanoparticles for drug delivery. Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R Nature reviews. Drug discovery 33277608 Nat Rev Drug Discov 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33277608
Cytosolic Delivery of Small Protein Scaffolds Enables Efficient Inhibition of Ras and Myc. Chan A, Wang HH, Haley RM, Song C, Gonzalez-Martinez D, Bugaj L, Mitchell MJ, Tsourkas A Molecular pharmaceutics 35225618 Mol Pharm 2022 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/35225618
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells. Patel SK, Billingsley MM, Frazee C, Han X, Swingle KL, Qin J, Alameh MG, Wang K, Weissman D, Mitchell MJ Journal of controlled release : official journal of the Controlled Release Society 35569584 J Control Release 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35569584
Piperazine-Derived Bisphosphonate-Based Ionizable Lipid Nanoparticles Enhance mRNA Delivery to the Bone Microenvironment. Yoon IC, Xue L, Chen Q, Liu J, Xu J, Siddiqui Z, Kim D, Chen B, Shi Q, Laura Han E, Cherry Ruiz M, Vining KH, Mitchell MJ Angewandte Chemie (International ed. in English) 39379320 Angew Chem Int Ed Engl 2025 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/39379320
Rational design of anti-inflammatory lipid nanoparticles for mRNA delivery. Zhang H, Han X, Alameh MG, Shepherd SJ, Padilla MS, Xue L, Butowska K, Weissman D, Mitchell MJ Journal of biomedical materials research. Part A 35076171 J Biomed Mater Res A 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35076171
In vivo bone marrow microenvironment siRNA delivery using lipid-polymer nanoparticles for multiple myeloma therapy. Guimarães PPG, Figueroa-Espada CG, Riley RS, Gong N, Xue L, Sewastianik T, Dennis PS, Loebel C, Chung A, Shepherd SJ, Haley RM, Hamilton AG, El-Mayta R, Wang K, Langer R, Anderson DG, Carrasco RD, Mitchell MJ Proceedings of the National Academy of Sciences of the United States of America 37310997 Proc Natl Acad Sci U S A 2023 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/37310997
siRNA Lipid-Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy. Figueroa-Espada CG, Guimarães PPG, Riley RS, Xue L, Wang K, Mitchell MJ Cellular and molecular bioengineering 37810998 Cell Mol Bioeng 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37810998
Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta. Safford HC, Swingle KL, Geisler HC, Hamilton AG, Thatte AS, Ghalsasi AA, Billingsley MM, Alameh MG, Weissman D, Mitchell MJ Small (Weinheim an der Bergstrasse, Germany) 37537704 Small 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/37537704
Nanoparticle protein corona: from structure and function to therapeutic targeting. Bashiri G, Padilla MS, Swingle KL, Shepherd SJ, Mitchell MJ, Wang K Lab on a chip 36655824 Lab Chip 2023 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/36655824
Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy. Metzloff AE, Padilla MS, Gong N, Billingsley MM, Han X, Merolle M, Mai D, Figueroa-Espada CG, Thatte AS, Haley RM, Mukalel AJ, Hamilton AG, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ Advanced materials (Deerfield Beach, Fla.) 38419362 Adv Mater 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38419362
In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells. Palanki R, Riley JS, Bose SK, Luks V, Dave A, Kus N, White BM, Ricciardi AS, Swingle KL, Xue L, Sung D, Thatte AS, Safford HC, Chaluvadi VS, Carpenter M, Han EL, Maganti R, Hamilton AG, Mrksich K, Billingsley MB, Zoltick PW, Alameh MG, Weissman D, Mitchell MJ, Peranteau WH Proceedings of the National Academy of Sciences of the United States of America 39078677 Proc Natl Acad Sci U S A 2024 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/39078677
Optimized microfluidic formulation and organic excipients for improved lipid nanoparticle mediated genome editing. Palanki R, Han EL, Murray AM, Maganti R, Tang S, Swingle KL, Kim D, Yamagata H, Safford HC, Mrksich K, Peranteau WH, Mitchell MJ Lab on a chip 39037068 Lab Chip 2024 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/39037068
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo. Han X, Alameh MG, Gong N, Xue L, Ghattas M, Bojja G, Xu J, Zhao G, Warzecha CC, Padilla MS, El-Mayta R, Dwivedi G, Xu Y, Vaughan AE, Wilson JM, Weissman D, Mitchell MJ Nature chemistry 38982196 Nat Chem 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/38982196
Breaking the final barrier: Evolution of cationic and ionizable lipid structure in lipid nanoparticles to escape the endosome. Mrksich K, Padilla MS, Mitchell MJ Advanced drug delivery reviews 39293650 Adv Drug Deliv Rev 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/39293650
Peptide-functionalized nanoparticles for brain-targeted therapeutics. Tang S, Han EL, Mitchell MJ Drug delivery and translational research 40164912 Drug Deliv Transl Res 2025 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/40164912
Microfluidic formulation of nanoparticles for biomedical applications. Shepherd SJ, Issadore D, Mitchell MJ Biomaterials 33965797 Biomaterials 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/33965797
Nanomaterial Interactions with Human Neutrophils. Bisso PW, Gaglione S, Guimarães PPG, Mitchell MJ, Langer R ACS biomaterials science & engineering 31497639 ACS Biomater Sci Eng 2018 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/31497639
Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening. Guimaraes PPG, Zhang R, Spektor R, Tan M, Chung A, Billingsley MM, El-Mayta R, Riley RS, Wang L, Wilson JM, Mitchell MJ Journal of controlled release : official journal of the Controlled Release Society 31678653 J Control Release 2019 Dec 28 https://www.ncbi.nlm.nih.gov/pubmed/31678653
Cyclodextrins in drug delivery: applications in gene and combination therapy. Haley RM, Gottardi R, Langer R, Mitchell MJ Drug delivery and translational research 32077052 Drug Deliv Transl Res 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32077052
Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering. Billingsley MM, Singh N, Ravikumar P, Zhang R, June CH, Mitchell MJ Nano letters 31951421 Nano Lett 2020 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/31951421
Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Zhao G, Xue L, Geisler HC, Xu J, Li X, Mitchell MJ, Vaughan AE Proceedings of the National Academy of Sciences of the United States of America 38315853 Proc Natl Acad Sci U S A 2024 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/38315853
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery. Patel SK, Billingsley MM, Mukalel AJ, Thatte AS, Hamilton AG, Gong N, El-Mayta R, Safford HC, Merolle M, Mitchell MJ Theranostics 38164140 Theranostics 2024 https://www.ncbi.nlm.nih.gov/pubmed/38164140
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism. Billingsley MM, Gong N, Mukalel AJ, Thatte AS, El-Mayta R, Patel SK, Metzloff AE, Swingle KL, Han X, Xue L, Hamilton AG, Safford HC, Alameh MG, Papp TE, Parhiz H, Weissman D, Mitchell MJ Small (Weinheim an der Bergstrasse, Germany) 38072809 Small 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38072809
Emerging strategies for nanomedicine in autoimmunity. Thatte AS, Billingsley MM, Weissman D, Melamed JR, Mitchell MJ Advanced drug delivery reviews 38342243 Adv Drug Deliv Rev 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38342243
Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device. Shepherd SJ, Warzecha CC, Yadavali S, El-Mayta R, Alameh MG, Wang L, Weissman D, Wilson JM, Issadore D, Mitchell MJ Nano letters 34189917 Nano Lett 2021 Jul 14 https://www.ncbi.nlm.nih.gov/pubmed/34189917
Nanotechnology-based strategies against SARS-CoV-2 variants. Huang X, Kon E, Han X, Zhang X, Kong N, Mitchell MJ, Peer D, Tao W Nature nanotechnology 35982317 Nat Nanotechnol 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/35982317
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity. Zhong W, Lu Y, Han X, Yang J, Qin Z, Zhang W, Yu Z, Wu B, Liu S, Xu W, Zheng C, Schuchter LM, Karakousis GC, Mitchell TC, Amaravadi R, Flowers AJ, Gimotty PA, Xiao M, Mills G, Herlyn M, Dong H, Mitchell MJ, Kim J, Xu X, Guo W Cell reports 37805922 Cell Rep 2023 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/37805922
Lipid Nanoparticle Delivery of Small Proteins for Potent In Vivo RAS Inhibition. Haley RM, Chan A, Billingsley MM, Gong N, Padilla MS, Kim EH, Wang H, Yin D, Wangensteen KJ, Tsourkas A, Mitchell MJ ACS applied materials & interfaces 37115558 ACS Appl Mater Interfaces 2023 May 10 https://www.ncbi.nlm.nih.gov/pubmed/37115558
Ionizable lipid nanoparticles for RAS protease delivery to inhibit cancer cell proliferation. Atsavapranee E, Haley RM, Billingsley MM, Chan A, Ruan B, Figueroa-Espada CG, Gong N, Mukalel AJ, Bryan PN, Mitchell MJ Journal of controlled release : official journal of the Controlled Release Society 38729436 J Control Release 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38729436
High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Xue L, Hamilton AG, Zhao G, Xiao Z, El-Mayta R, Han X, Gong N, Xiong X, Xu J, Figueroa-Espada CG, Shepherd SJ, Mukalel AJ, Alameh MG, Cui J, Wang K, Vaughan AE, Weissman D, Mitchell MJ Nature communications 38424061 Nat Commun 2024 Feb 29 https://www.ncbi.nlm.nih.gov/pubmed/38424061
Lipid nanoparticle-mediated RNA delivery for immune cell modulation. Kim EH, Teerdhala SV, Padilla MS, Joseph RA, Li JJ, Haley RM, Mitchell MJ European journal of immunology 39279550 Eur J Immunol 2024 Dec https://www.ncbi.nlm.nih.gov/pubmed/39279550
Plug-and-play assembly of biodegradable ionizable lipids for potent mRNA delivery and gene editing in vivo. Han X, Xu Y, Ricciardi A, Xu J, Palanki R, Chowdhary V, Xue L, Gong N, Alameh MG, Peranteau WH, Wilson JM, Weissman D, Mitchell MJ bioRxiv : the preprint server for biology 40060499 bioRxiv 2025 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/40060499
Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering. Padilla MS, Mrksich K, Wang Y, Haley RM, Li JJ, Han EL, El-Mayta R, Kim EH, Dias S, Gong N, Teerdhala SV, Han X, Chowdhary V, Xue L, Siddiqui Z, Yamagata HM, Kim D, Yoon IC, Wilson JM, Radhakrishnan R, Mitchell MJ Nature communications 39856035 Nat Commun 2025 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/39856035
Nanoparticles for nucleic acid delivery: Applications in cancer immunotherapy. Mukalel AJ, Riley RS, Zhang R, Mitchell MJ Cancer letters 31100411 Cancer Lett 2019 Aug 28 https://www.ncbi.nlm.nih.gov/pubmed/31100411
A (Controlled) Spill of IL2 for Localized Treatment of Mesothelioma. Palanki R, Swingle KL, Mitchell MJ Clinical cancer research : an official journal of the American Association for Cancer Research 36190329 Clin Cancer Res 2022 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/36190329
Testing the In Vitro and In Vivo Efficiency of mRNA-Lipid Nanoparticles Formulated by Microfluidic Mixing. El-Mayta R, Padilla MS, Billingsley MM, Han X, Mitchell MJ Journal of visualized experiments : JoVE 36744791 J Vis Exp 2023 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/36744791
Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery. Swingle KL, Billingsley MM, Bose SK, White B, Palanki R, Dave A, Patel SK, Gong N, Hamilton AG, Alameh MG, Weissman D, Peranteau WH, Mitchell MJ Journal of controlled release : official journal of the Controlled Release Society 34742747 J Control Release 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34742747
Biomaterials for vaccine-based cancer immunotherapy. Zhang R, Billingsley MM, Mitchell MJ Journal of controlled release : official journal of the Controlled Release Society 30312721 J Control Release 2018 Dec 28 https://www.ncbi.nlm.nih.gov/pubmed/30312721
Delivery technologies for cancer immunotherapy. Riley RS, June CH, Langer R, Mitchell MJ Nature reviews. Drug discovery 30622344 Nat Rev Drug Discov 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30622344
Delivery technologies for in utero gene therapy. Palanki R, Peranteau WH, Mitchell MJ Advanced drug delivery reviews 33181188 Adv Drug Deliv Rev 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33181188
Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction. Huang M, Yang F, Zhang D, Lin M, Duan H, El-Mayta R, Zhang L, Qin L, Shewale SV, Pei L, Mitchell MJ, Rader DJ, Fan Y, Gong Y Nature cardiovascular research 35571674 Nat Cardiovasc Res 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35571674
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA. Zhang D, Atochina-Vasserman EN, Maurya DS, Huang N, Xiao Q, Ona N, Liu M, Shahnawaz H, Ni H, Kim K, Billingsley MM, Pochan DJ, Mitchell MJ, Weissman D, Percec V Journal of the American Chemical Society 34324336 J Am Chem Soc 2021 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/34324336
Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying length. Mrksich K, Padilla MS, Joseph RA, Han EL, Kim D, Palanki R, Xu J, Mitchell MJ Journal of biomedical materials research. Part A 38487970 J Biomed Mater Res A 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/38487970
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy. Swingle KL, Safford HC, Geisler HC, Hamilton AG, Thatte AS, Billingsley MM, Joseph RA, Mrksich K, Padilla MS, Ghalsasi AA, Alameh MG, Weissman D, Mitchell MJ Journal of the American Chemical Society 36789893 J Am Chem Soc 2023 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/36789893
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines. Han X, Alameh MG, Butowska K, Knox JJ, Lundgreen K, Ghattas M, Gong N, Xue L, Xu Y, Lavertu M, Bates P, Xu J, Nie G, Zhong Y, Weissman D, Mitchell MJ Nature nanotechnology 37365276 Nat Nanotechnol 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37365276
Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease. Palanki R, Bose SK, Dave A, White BM, Berkowitz C, Luks V, Yaqoob F, Han E, Swingle KL, Menon P, Hodgson E, Biswas A, Billingsley MM, Li L, Yiping F, Carpenter M, Trokhan A, Yeo J, Johana N, Wan TY, Alameh MG, Bennett FC, Storm PB, Jain R, Chan J, Weissman D, Mitchell MJ, Peranteau WH ACS nano 37458484 ACS Nano 2023 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/37458484
Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery. Gong N, Zhong W, Alameh MG, Han X, Xue L, El-Mayta R, Zhao G, Vaughan AE, Qin Z, Xu F, Hamilton AG, Kim D, Xu J, Kim J, Teng X, Li J, Liang XJ, Weissman D, Guo W, Mitchell MJ Nature materials 39223270 Nat Mater 2024 Dec https://www.ncbi.nlm.nih.gov/pubmed/39223270
EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta. Geisler HC, Ghalsasi AA, Safford HC, Swingle KL, Thatte AS, Mukalel AJ, Gong N, Hamilton AG, Han EL, Nachod BE, Padilla MS, Mitchell MJ Journal of controlled release : official journal of the Controlled Release Society 38789090 J Control Release 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38789090
Enhancing in situ cancer vaccines using delivery technologies. Gong N, Alameh MG, El-Mayta R, Xue L, Weissman D, Mitchell MJ Nature reviews. Drug discovery 38951662 Nat Rev Drug Discov 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38951662
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines. Shepherd SJ, Han X, Mukalel AJ, El-Mayta R, Thatte AS, Wu J, Padilla MS, Alameh MG, Srikumar N, Lee D, Weissman D, Issadore D, Mitchell MJ Proceedings of the National Academy of Sciences of the United States of America 37556502 Proc Natl Acad Sci U S A 2023 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/37556502
Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering. Hamilton AG, Swingle KL, Joseph RA, Mai D, Gong N, Billingsley MM, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ Advanced healthcare materials 37602495 Adv Healthc Mater 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37602495
Predictive High-Throughput Platform for Dual Screening of mRNA Lipid Nanoparticle Blood-Brain Barrier Transfection and Crossing. Han EL, Padilla MS, Palanki R, Kim D, Mrksich K, Li JJ, Tang S, Yoon IC, Mitchell MJ Nano letters 38259198 Nano Lett 2024 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/38259198
Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering. Mukalel AJ, Hamilton AG, Billingsley MM, Li J, Thatte AS, Han X, Safford HC, Padilla MS, Papp T, Parhiz H, Weissman D, Mitchell MJ Advanced functional materials 39628840 Adv Funct Mater 2024 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/39628840
Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery. Xue L, Zhao G, Gong N, Han X, Shepherd SJ, Xiong X, Xiao Z, Palanki R, Xu J, Swingle KL, Warzecha CC, El-Mayta R, Chowdhary V, Yoon IC, Xu J, Cui J, Shi Y, Alameh MG, Wang K, Wang L, Pochan DJ, Weissman D, Vaughan AE, Wilson JM, Mitchell MJ Nature nanotechnology 39354147 Nat Nanotechnol 2025 Jan https://www.ncbi.nlm.nih.gov/pubmed/39354147
Measuring Vascular Permeability In Vivo. Meijer EF, Baish JW, Padera TP, Fukumura D Methods in molecular biology (Clifton, N.J.) 27581015 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/27581015
Growth and Immune Evasion of Lymph Node Metastasis. Jones D, Pereira ER, Padera TP Frontiers in oncology 29527513 Front Oncol 2018 https://www.ncbi.nlm.nih.gov/pubmed/29527513
Targeting CXCR4-dependent immunosuppressive Ly6C(low) monocytes improves antiangiogenic therapy in colorectal cancer. Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D Proceedings of the National Academy of Sciences of the United States of America 28900008 Proc Natl Acad Sci U S A 2017 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/28900008
Simultaneous measurements of lymphatic vessel contraction, flow and valve dynamics in multiple lymphangions using optical coherence tomography. Blatter C, Meijer EFJ, Padera TP, Vakoc BJ Journal of biophotonics 28700145 J Biophotonics 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/28700145
Lymphatic function measurements influenced by contrast agent volume and body position. Bouta EM, Blatter C, Ruggieri TA, Meijer EF, Munn LL, Vakoc BJ, Padera TP JCI insight 29367467 JCI Insight 2018 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/29367467
Novel molecular pathways in Gorham disease: implications for treatment. Hagendoorn J, Yock TI, Borel Rinkes IH, Padera TP, Ebb DH Pediatric blood & cancer 24214028 Pediatr Blood Cancer 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24214028
Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment. Kirkpatrick ND, Chung E, Cook DC, Han X, Gruionu G, Liao S, Munn LL, Padera TP, Fukumura D, Jain RK Intravital 24353926 Intravital 2012 https://www.ncbi.nlm.nih.gov/pubmed/24353926
Cardiac and inflammatory biomarkers do not correlate with volume of heart or lung receiving radiation. Kuo AH, Ancukiewicz M, Kozak KR, Yock TI, Padera TP Radiation oncology (London, England) 25573181 Radiat Oncol 2015 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/25573181
Lymphatic vessels in health and disease. Kesler CT, Liao S, Munn LL, Padera TP Wiley interdisciplinary reviews. Systems biology and medicine 23209022 Wiley Interdiscip Rev Syst Biol Med 2013 Jan-Feb https://www.ncbi.nlm.nih.gov/pubmed/23209022
In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography. Blatter C, Meijer EF, Nam AS, Jones D, Bouma BE, Padera TP, Vakoc BJ Scientific reports 27377852 Sci Rep 2016 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/27377852
Imaging the lymphatic system. Munn LL, Padera TP Microvascular research 24956510 Microvasc Res 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/24956510
Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure. Chauhan VP, Boucher Y, Ferrone CR, Roberge S, Martin JD, Stylianopoulos T, Bardeesy N, DePinho RA, Padera TP, Munn LL, Jain RK Cancer cell 25026209 Cancer Cell 2014 Jul 14 https://www.ncbi.nlm.nih.gov/pubmed/25026209
A retrospective analysis of commonly prescribed medications and the risk of developing breast cancer related lymphedema. Meijer EF, Bouta EM, Mendonca C, Skolny MN, Salama LW, Taghian AG, Padera TP Clinical research and trials 32864167 Clin Res Trials 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/32864167
Synchronization and Random Triggering of Lymphatic Vessel Contractions. Baish JW, Kunert C, Padera TP, Munn LL PLoS computational biology 27935958 PLoS Comput Biol 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27935958
Murine chronic lymph node window for longitudinal intravital lymph node imaging. Meijer EFJ, Jeong HS, Pereira ER, Ruggieri TA, Blatter C, Vakoc BJ, Padera TP Nature protocols 28683064 Nat Protoc 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28683064
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D The Journal of clinical investigation 28691930 J Clin Invest 2017 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/28691930
Solid stress and elastic energy as measures of tumour mechanopathology. Nia HT, Liu H, Seano G, Datta M, Jones D, Rahbari N, Incio J, Chauhan VP, Jung K, Martin JD, Askoxylakis V, Padera TP, Fukumura D, Boucher Y, Hornicek FJ, Grodzinsky AJ, Baish JW, Munn LL, Jain RK Nature biomedical engineering 28966873 Nat Biomed Eng 2016 https://www.ncbi.nlm.nih.gov/pubmed/28966873
Significance of lymph node metastasis in cancer dissemination of head and neck cancer. Cho JK, Hyun SH, Choi N, Kim MJ, Padera TP, Choi JY, Jeong HS Translational oncology 25926078 Transl Oncol 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25926078
Local failure in parameningeal rhabdomyosarcoma correlates with poor response to induction chemotherapy. Ladra MM, Mandeville HC, Niemierko A, Padera TP, Friedmann AM, MacDonald SM, Ebb D, Chen YL, Tarbell NJ, Yock TI International journal of radiation oncology, biology, physics 25864172 Int J Radiat Oncol Biol Phys 2015 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/25864172
Reply to Davis: Nitric oxide regulates lymphatic contractions. Kunert C, Baish JW, Liao S, Padera TP, Munn LL Proceedings of the National Academy of Sciences of the United States of America 26719425 Proc Natl Acad Sci U S A 2016 Jan 12 https://www.ncbi.nlm.nih.gov/pubmed/26719425
Inducible Nitric Oxide Synthase and CD11b(+)Gr1(+) Cells Impair Lymphatic Contraction of Tumor-Draining Lymphatic Vessels. Liao S, Bouta EM, Morris LM, Jones D, Jain RK, Padera TP Lymphatic research and biology 30358484 Lymphat Res Biol 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/30358484
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium. Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, Wen PY, Lin NU, Grodzinsky AJ, Fukumura D, Huang P, Baish JW, Padera TP, Munn LL, Jain RK Nature biomedical engineering 30948807 Nat Biomed Eng 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30948807
Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation. Kesler CT, Pereira ER, Cui CH, Nelson GM, Masuck DJ, Baish JW, Padera TP FASEB journal : official publication of the Federation of American Societies for Experimental Biology 25977256 FASEB J 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/25977256
Method for the quantitative measurement of collecting lymphatic vessel contraction in mice. Liao S, Jones D, Cheng G, Padera TP Journal of biological methods 25512945 J Biol Methods 2014 https://www.ncbi.nlm.nih.gov/pubmed/25512945
Lymph node effective vascular permeability and chemotherapy uptake. Meijer EFJ, Blatter C, Chen IX, Bouta E, Jones D, Pereira ER, Jung K, Vakoc BJ, Baish JW, Padera TP Microcirculation (New York, N.Y. : 1994) 28510992 Microcirculation 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28510992
The Lymphatic System in Disease Processes and Cancer Progression. Padera TP, Meijer EF, Munn LL Annual review of biomedical engineering 26863922 Annu Rev Biomed Eng 2016 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/26863922
Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression. Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Kirkpatrick ND, Heishi T, Huang Y, Martin JD, Ager E, Samuel R, Wang S, Yazbek J, Vakoc BJ, Peterson RT, Padera TP, Duda DG, Fukumura D, Jain RK Journal of the National Cancer Institute 23899555 J Natl Cancer Inst 2013 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/23899555
Lymphatic function and immune regulation in health and disease. Liao S, Padera TP Lymphatic research and biology 24024577 Lymphat Res Biol 2013 Sep https://www.ncbi.nlm.nih.gov/pubmed/24024577
Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells. Kesler CT, Kuo AH, Wong HK, Masuck DJ, Shah JL, Kozak KR, Held KD, Padera TP Angiogenesis 24201897 Angiogenesis 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24201897
Editorial: rapid growth in the field of lymphatic biology. Padera TP Seminars in cell & developmental biology 25868083 Semin Cell Dev Biol 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25868083
Fate Mapping of Cancer Cells in Metastatic Lymph Nodes Using Photoconvertible Proteins. Pereira ER, Kedrin D, Padera TP Methods in molecular biology (Clifton, N.J.) 33704727 Methods Mol Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33704727
Solid stress impairs lymphocyte infiltration into lymph-node metastases. Jones D, Wang Z, Chen IX, Zhang S, Banerji R, Lei PJ, Zhou H, Xiao V, Kwong C, van Wijnbergen JWM, Pereira ER, Vakoc BJ, Huang P, Nia HT, Padera TP Nature biomedical engineering 34282290 Nat Biomed Eng 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34282290
Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction. Jones D, Meijer EFJ, Blatter C, Liao S, Pereira ER, Bouta EM, Jung K, Chin SM, Huang P, Munn LL, Vakoc BJ, Otto M, Padera TP Science translational medicine 29343625 Sci Transl Med 2018 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/29343625
Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice. Pereira ER, Kedrin D, Seano G, Gautier O, Meijer EFJ, Jones D, Chin SM, Kitahara S, Bouta EM, Chang J, Beech E, Jeong HS, Carroll MC, Taghian AG, Padera TP Science (New York, N.Y.) 29567713 Science 2018 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/29567713
The lymph node microenvironment and its role in the progression of metastatic cancer. Pereira ER, Jones D, Jung K, Padera TP Seminars in cell & developmental biology 25620792 Semin Cell Dev Biol 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25620792
Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases. Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP Journal of the National Cancer Institute 26063793 J Natl Cancer Inst 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26063793
Mechanobiological oscillators control lymph flow. Kunert C, Baish JW, Liao S, Padera TP, Munn LL Proceedings of the National Academy of Sciences of the United States of America 26283382 Proc Natl Acad Sci U S A 2015 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/26283382
Kinetochore components are required for central spindle assembly. Maton G, Edwards F, Lacroix B, Stefanutti M, Laband K, Lieury T, Kim T, Espeut J, Canman JC, Dumont J Nature cell biology 25866924 Nat Cell Biol 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25866924
Kinetochore components are required for central spindle assembly. Maton G, Edwards F, Lacroix B, Stefanutti M, Laband K, Lieury T, Kim T, Espeut J, Canman JC, Dumont J Nature cell biology 26123112 Nat Cell Biol 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/26123112
Using fast-acting temperature-sensitive mutants to study cell division in Caenorhabditis elegans. Davies T, Sundaramoorthy S, Jordan SN, Shirasu-Hiza M, Dumont J, Canman JC Methods in cell biology 28065312 Methods Cell Biol 2017 https://www.ncbi.nlm.nih.gov/pubmed/28065312
CYK-4 regulates Rac, but not Rho, during cytokinesis. Zhuravlev Y, Hirsch SM, Jordan SN, Dumont J, Shirasu-Hiza M, Canman JC Molecular biology of the cell 28298491 Mol Biol Cell 2017 May 1 https://www.ncbi.nlm.nih.gov/pubmed/28298491
High-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis. Davies T, Jordan SN, Chand V, Sees JA, Laband K, Carvalho AX, Shirasu-Hiza M, Kovar DR, Dumont J, Canman JC Developmental cell 25073157 Dev Cell 2014 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/25073157
Cell-intrinsic and -extrinsic mechanisms promote cell-type-specific cytokinetic diversity. Davies T, Kim HX, Romano Spica N, Lesea-Pringle BJ, Dumont J, Shirasu-Hiza M, Canman JC eLife 30028292 Elife 2018 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/30028292
Rho GTPases in animal cell cytokinesis: an occupation by the one percent. Jordan SN, Canman JC Cytoskeleton (Hoboken, N.J.) 23047851 Cytoskeleton (Hoboken) 2012 Nov https://www.ncbi.nlm.nih.gov/pubmed/23047851
Dietary Restriction Extends the Lifespan of Circadian Mutants tim and per. Ulgherait M, Chen A, Oliva MK, Kim HX, Canman JC, Ja WW, Shirasu-Hiza M Cell metabolism 27916531 Cell Metab 2016 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/27916531
A Drosophila model of Fragile X syndrome exhibits defects in phagocytosis by innate immune cells. O'Connor RM, Stone EF, Wayne CR, Marcinkevicius EV, Ulgherait M, Delventhal R, Pantalia MM, Hill VM, Zhou CG, McAllister S, Chen A, Ziegenfuss JS, Grueber WB, Canman JC, Shirasu-Hiza MM The Journal of cell biology 28223318 J Cell Biol 2017 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/28223318
Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes. Gigant E, Stefanutti M, Laband K, Gluszek-Kustusz A, Edwards F, Lacroix B, Maton G, Canman JC, Welburn JPI, Dumont J Development (Cambridge, England) 28289130 Development 2017 May 1 https://www.ncbi.nlm.nih.gov/pubmed/28289130
Stuck in the middle: Rac, adhesion, and cytokinesis. Davies T, Canman JC The Journal of cell biology 22945931 J Cell Biol 2012 Sep 3 https://www.ncbi.nlm.nih.gov/pubmed/22945931
period-Regulated Feeding Behavior and TOR Signaling Modulate Survival of Infection. Allen VW, O'Connor RM, Ulgherait M, Zhou CG, Stone EF, Hill VM, Murphy KR, Canman JC, Ja WW, Shirasu-Hiza MM Current biology : CB 26748856 Curr Biol 2016 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/26748856
period-Regulated Feeding Behavior and TOR Signaling Modulate Survival of Infection. Allen VW, O'Connor RM, Ulgherait M, Zhou CG, Stone EF, Hill VM, Murphy KR, Canman JC, Ja WW, Shirasu-Hiza MM Current biology : CB 27218838 Curr Biol 2016 May 23 https://www.ncbi.nlm.nih.gov/pubmed/27218838
FLIRT: fast local infrared thermogenetics for subcellular control of protein function. Hirsch SM, Sundaramoorthy S, Davies T, Zhuravlev Y, Waters JC, Shirasu-Hiza M, Dumont J, Canman JC Nature methods 30377360 Nat Methods 2018 Nov https://www.ncbi.nlm.nih.gov/pubmed/30377360
Microtubule Dynamics Scale with Cell Size to Set Spindle Length and Assembly Timing. Lacroix B, Letort G, Pitayu L, Sallé J, Stefanutti M, Maton G, Ladouceur AM, Canman JC, Maddox PS, Maddox AS, Minc N, Nédélec F, Dumont J Developmental cell 29787710 Dev Cell 2018 May 21 https://www.ncbi.nlm.nih.gov/pubmed/29787710
Cortical PAR polarity proteins promote robust cytokinesis during asymmetric cell division. Jordan SN, Davies T, Zhuravlev Y, Dumont J, Shirasu-Hiza M, Canman JC The Journal of cell biology 26728855 J Cell Biol 2016 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/26728855
Low Efficiency Upconversion Nanoparticles for High-Resolution Coalignment of Near-Infrared and Visible Light Paths on a Light Microscope. Sundaramoorthy S, Garcia Badaracco A, Hirsch SM, Park JH, Davies T, Dumont J, Shirasu-Hiza M, Kummel AC, Canman JC ACS applied materials & interfaces 28221018 ACS Appl Mater Interfaces 2017 Mar 8 https://www.ncbi.nlm.nih.gov/pubmed/28221018
Effect of Competitive Surface Functionalization on Dual-Modality Fluorescence and Magnetic Resonance Imaging of Single-Walled Carbon Nanotubes. Hong T, Lazarenko RM, Colvin DC, Flores RL, Zhang Q, Xu YQ The journal of physical chemistry. C, Nanomaterials and interfaces 26644813 J Phys Chem C Nanomater Interfaces 2012 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/26644813
Ammonium chloride alters neuronal excitability and synaptic vesicle release. Lazarenko RM, DelBove CE, Strothman CE, Zhang Q Scientific reports 28698583 Sci Rep 2017 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/28698583
A Stem Cell-Derived Platform for Studying Single Synaptic Vesicles in Dopaminergic Synapses. Gu H, Lazarenko RM, Koktysh D, Iacovitti L, Zhang Q Stem cells translational medicine 26025981 Stem Cells Transl Med 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26025981
Fluorescent Measurement of Synaptic Activity Using FM Dyes in Dissociated Hippocampal Cultured Neurons. Lazarenko RM, DelBove CE, Zhang Q Bio-protocol 29552593 Bio Protoc 2018 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/29552593
Reciprocal modulation between amyloid precursor protein and synaptic membrane cholesterol revealed by live cell imaging. DelBove CE, Strothman CE, Lazarenko RM, Huang H, Sanders CR, Zhang Q Neurobiology of disease 30885793 Neurobiol Dis 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/30885793
Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis: Implications for Scleroderma. Mitra A, Luna JI, Marusina AI, Merleev A, Kundu-Raychaudhuri S, Fiorentino D, Raychaudhuri SP, Maverakis E The Journal of investigative dermatology 26134944 J Invest Dermatol 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26134944
Serum levels of innate immunity cytokines are elevated in dogs with metaphyseal osteopathy (hypertrophic osteodytrophy) during active disease and remission. Safra N, Hitchens PL, Maverakis E, Mitra A, Korff C, Johnson E, Kol A, Bannasch MJ, Pedersen NC, Bannasch DL Veterinary immunology and immunopathology 27590423 Vet Immunol Immunopathol 2016 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/27590423
Salmonella Typhimurium Enzymatically Landscapes the Host Intestinal Epithelial Cell (IEC) Surface Glycome to Increase Invasion. Park D, Arabyan N, Williams CC, Song T, Mitra A, Weimer BC, Maverakis E, Lebrilla CB Molecular & cellular proteomics : MCP 27754876 Mol Cell Proteomics 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27754876
Meta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A. Merleev AA, Marusina AI, Ma C, Elder JT, Tsoi LC, Raychaudhuri SP, Weidinger S, Wang EA, Adamopoulos IE, Luxardi G, Gudjonsson JE, Shimoda M, Maverakis E JCI insight 29997305 JCI Insight 2018 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/29997305
Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. Sun Y, Reid B, Ferreira F, Luxardi G, Ma L, Lokken KL, Zhu K, Xu G, Sun Y, Ryzhuk V, Guo BP, Lebrilla CB, Maverakis E, Mogilner A, Zhao M PLoS biology 30964858 PLoS Biol 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30964858
NKG2C, HLA-E and their association with psoriasis. Patel F, Marusina AI, Duong C, Adamopoulos IE, Maverakis E Experimental dermatology 24279916 Exp Dermatol 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/24279916
Characteristic Changes in Cell Surface Glycosylation Accompany Intestinal Epithelial Cell (IEC) Differentiation: High Mannose Structures Dominate the Cell Surface Glycome of Undifferentiated Enterocytes. Park D, Brune KA, Mitra A, Marusina AI, Maverakis E, Lebrilla CB Molecular & cellular proteomics : MCP 26355101 Mol Cell Proteomics 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26355101
Classic Ulcerative Pyoderma Gangrenosum Is a T Cell-Mediated Disease Targeting Follicular Adnexal Structures: A Hypothesis Based on Molecular and Clinicopathologic Studies. Wang EA, Steel A, Luxardi G, Mitra A, Patel F, Cheng MY, Wilken R, Kao J, de Ga K, Sultani H, Merleev AA, Marusina AI, Brassard A, Fung MA, Konia T, Shimoda M, Maverakis E Frontiers in immunology 29379508 Front Immunol 2017 https://www.ncbi.nlm.nih.gov/pubmed/29379508
Trends in National Institutes of Health Funding of Principal Investigators in Dermatology Research by Academic Degree and Sex. Cheng MY, Sukhov A, Sultani H, Kim K, Maverakis E JAMA dermatology 27191545 JAMA Dermatol 2016 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/27191545
Surface Glycans Regulate Salmonella Infection-Dependent Directional Switch in Macrophage Galvanotaxis Independent of NanH. Sun YH, Luxardi G, Xu G, Zhu K, Reid B, Guo BP, Lebrilla CB, Maverakis E, Zhao M Infection and immunity 34662214 Infect Immun 2022 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/34662214
Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review. Maverakis E, Kim K, Shimoda M, Gershwin ME, Patel F, Wilken R, Raychaudhuri S, Ruhaak LR, Lebrilla CB Journal of autoimmunity 25578468 J Autoimmun 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25578468
Clonal Vγ6(+)Vδ4(+) T cells promote IL-17-mediated immunity against Staphylococcus aureus skin infection. Marchitto MC, Dillen CA, Liu H, Miller RJ, Archer NK, Ortines RV, Alphonse MP, Marusina AI, Merleev AA, Wang Y, Pinsker BL, Byrd AS, Brown ID, Ravipati A, Zhang E, Cai SS, Limjunyawong N, Dong X, Yeaman MR, Simon SI, Shen W, Durum SK, O'Brien RL, Maverakis E, Miller LS Proceedings of the National Academy of Sciences of the United States of America 31088972 Proc Natl Acad Sci U S A 2019 May 28 https://www.ncbi.nlm.nih.gov/pubmed/31088972
Peristomal pyoderma gangrenosum: An exceedingly rare and overdiagnosed entity? Le ST, Wang JZ, Alexanian C, Ellis S, Martinez-Alvarado YC, Johng S, Sood A, Maverakis E Journal of the American Academy of Dermatology 30772334 J Am Acad Dermatol 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/30772334
Glycan biomarkers of autoimmunity and bile acid-associated alterations of the human glycome: Primary biliary cirrhosis and primary sclerosing cholangitis-specific glycans. Maverakis E, Merleev AA, Park D, Kailemia MJ, Xu G, Ruhaak LR, Kim K, Hong Q, Li Q, Leung P, Liakos W, Wan YY, Bowlus CL, Marusina AI, Lal NN, Xie Y, Luxardi G, Lebrilla CB Clinical immunology (Orlando, Fla.) 34403816 Clin Immunol 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34403816
Interactions of the Immune System with Skin and Bone Tissue in Psoriatic Arthritis: A Comprehensive Review. Sukhov A, Adamopoulos IE, Maverakis E Clinical reviews in allergy & immunology 26780035 Clin Rev Allergy Immunol 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/26780035
Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes. Merleev AA, Le ST, Alexanian C, Toussi A, Xie Y, Marusina AI, Watkins SM, Patel F, Billi AC, Wiedemann J, Izumiya Y, Kumar A, Uppala R, Kahlenberg JM, Liu FT, Adamopoulos IE, Wang EA, Ma C, Cheng MY, Xiong H, Kirane A, Luxardi G, Andersen B, Tsoi LC, Lebrilla CB, Gudjonsson JE, Maverakis E JCI insight 35900871 JCI Insight 2022 Aug 22 https://www.ncbi.nlm.nih.gov/pubmed/35900871
Controlling the Release of Small, Bioactive Proteins via Dual Mechanisms with Therapeutic Potential. Kharkar PM, Scott RA, Olney LP, LeValley PJ, Maverakis E, Kiick KL, Kloxin AM Advanced healthcare materials 29024487 Adv Healthc Mater 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/29024487
Oncolytic Reactivation of KSHV as a Therapeutic Approach for Primary Effusion Lymphoma. Zhou F, Shimoda M, Olney L, Lyu Y, Tran K, Jiang G, Nakano K, Davis RR, Tepper CG, Maverakis E, Campbell M, Li Y, Dandekar S, Izumiya Y Molecular cancer therapeutics 28847988 Mol Cancer Ther 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28847988
Membrane glycomics reveal heterogeneity and quantitative distribution of cell surface sialylation. Park DD, Xu G, Wong M, Phoomak C, Liu M, Haigh NE, Wongkham S, Yang P, Maverakis E, Lebrilla CB Chemical science 30123482 Chem Sci 2018 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/30123482
A Method for Comprehensive Glycosite-Mapping and Direct Quantitation of Serum Glycoproteins. Hong Q, Ruhaak LR, Stroble C, Parker E, Huang J, Maverakis E, Lebrilla CB Journal of proteome research 26510530 J Proteome Res 2015 Dec 4 https://www.ncbi.nlm.nih.gov/pubmed/26510530
Metastasis of cholangiocarcinoma is promoted by extended high-mannose glycans. Park DD, Phoomak C, Xu G, Olney LP, Tran KA, Park SS, Haigh NE, Luxardi G, Lert-Itthiporn W, Shimoda M, Li Q, Matoba N, Fierro F, Wongkham S, Maverakis E, Lebrilla CB Proceedings of the National Academy of Sciences of the United States of America 32213588 Proc Natl Acad Sci U S A 2020 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/32213588
Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection. Dillen CA, Pinsker BL, Marusina AI, Merleev AA, Farber ON, Liu H, Archer NK, Lee DB, Wang Y, Ortines RV, Lee SK, Marchitto MC, Cai SS, Ashbaugh AG, May LS, Holland SM, Freeman AF, Miller LG, Yeaman MR, Simon SI, Milner JD, Maverakis E, Miller LS The Journal of clinical investigation 29400698 J Clin Invest 2018 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/29400698
A Phase I Study of the Combination of Rituximab and Ipilimumab in Patients with Relapsed/Refractory B-Cell Lymphoma. Tuscano JM, Maverakis E, Groshen S, Tsao-Wei D, Luxardi G, Merleev AA, Beaven A, DiPersio JF, Popplewell L, Chen R, Kirschbaum M, Schroeder MA, Newman EM Clinical cancer research : an official journal of the American Association for Cancer Research 31481504 Clin Cancer Res 2019 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/31481504
International consensus criteria for the diagnosis of Raynaud's phenomenon. Maverakis E, Patel F, Kronenberg DG, Chung L, Fiorentino D, Allanore Y, Guiducci S, Hesselstrand R, Hummers LK, Duong C, Kahaleh B, Macgregor A, Matucci-Cerinic M, Wollheim FA, Mayes MD, Gershwin ME Journal of autoimmunity 24491823 J Autoimmun 2014 Feb-Mar https://www.ncbi.nlm.nih.gov/pubmed/24491823
T cell clonal expansions detected in patients with primary biliary cirrhosis express CX3CR1. Zhang W, Ono Y, Miyamura Y, Bowlus CL, Gershwin ME, Maverakis E Journal of autoimmunity 21636249 J Autoimmun 2011 Sep https://www.ncbi.nlm.nih.gov/pubmed/21636249
ITK inhibition for the targeted treatment of CTCL. Bustos-Villalobos I, Bergstrom JW, Haigh NE, Luna JI, Mitra A, Marusina AI, Merleev AA, Wang EA, Sukhov A, Sultani H, Liu R, Bhardwaj G, Guo W, Kung HJ, Lam KS, Maverakis E Journal of dermatological science 28434812 J Dermatol Sci 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28434812
Persistence of Autoreactive IgA-Secreting B Cells Despite Multiple Immunosuppressive Medications Including Rituximab. He Y, Shimoda M, Ono Y, Villalobos IB, Mitra A, Konia T, Grando SA, Zone JJ, Maverakis E JAMA dermatology 25901938 JAMA Dermatol 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25901938
CD4(+) virtual memory: Antigen-inexperienced T cells reside in the naïve, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity. Marusina AI, Ono Y, Merleev AA, Shimoda M, Ogawa H, Wang EA, Kondo K, Olney L, Luxardi G, Miyamura Y, Yilma TD, Villalobos IB, Bergstrom JW, Kronenberg DG, Soulika AM, Adamopoulos IE, Maverakis E Journal of autoimmunity 27894837 J Autoimmun 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/27894837
γδ T cells in rheumatic diseases: from fundamental mechanisms to autoimmunity. Nguyen CT, Maverakis E, Eberl M, Adamopoulos IE Seminars in immunopathology 31506867 Semin Immunopathol 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31506867
A site-specific map of the human plasma glycome and its age and gender-associated alterations. Merleev AA, Park D, Xie Y, Kailemia MJ, Xu G, Ruhaak LR, Kim K, Hong Q, Li Q, Patel F, Wan YY, Marusina AI, Adamopoulos IE, Lal NN, Mitra A, Le ST, Shimoda M, Luxardi G, Lebrilla CB, Maverakis E Scientific reports 33060657 Sci Rep 2020 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/33060657
HDL Glycoprotein Composition and Site-Specific Glycosylation Differentiates Between Clinical Groups and Affects IL-6 Secretion in Lipopolysaccharide-Stimulated Monocytes. Krishnan S, Shimoda M, Sacchi R, Kailemia MJ, Luxardi G, Kaysen GA, Parikh AN, Ngassam VN, Johansen K, Chertow GM, Grimes B, Smilowitz JT, Maverakis E, Lebrilla CB, Zivkovic AM Scientific reports 28287093 Sci Rep 2017 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/28287093
Regeneration and experimental orthotopic transplantation of a bioengineered kidney. Song JJ, Guyette JP, Gilpin SE, Gonzalez G, Vacanti JP, Ott HC Nature medicine 23584091 Nat Med 2013 May https://www.ncbi.nlm.nih.gov/pubmed/23584091
Perfusion Decellularization of Discarded Human Kidneys: A Valuable Platform for Organ Regeneration. Ott HC Transplantation 26203856 Transplantation 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26203856
Engineering pulmonary vasculature in decellularized rat and human lungs. Ren X, Moser PT, Gilpin SE, Okamoto T, Wu T, Tapias LF, Mercier FE, Xiong L, Ghawi R, Scadden DT, Mathisen DJ, Ott HC Nature biotechnology 26368048 Nat Biotechnol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26368048
Design and validation of a clinical-scale bioreactor for long-term isolated lung culture. Charest JM, Okamoto T, Kitano K, Yasuda A, Gilpin SE, Mathisen DJ, Ott HC Biomaterials 25818415 Biomaterials 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25818415
Ex vivo non-invasive assessment of cell viability and proliferation in bio-engineered whole organ constructs. Ren X, Tapias LF, Jank BJ, Mathisen DJ, Lanuti M, Ott HC Biomaterials 25818417 Biomaterials 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25818417
Creation of a Bioengineered Skin Flap Scaffold with a Perfusable Vascular Pedicle. Jank BJ, Goverman J, Guyette JP, Charest JM, Randolph M, Gaudette GR, Gershlak JR, Purschke M, Javorsky E, Nazarian RM, Leonard DA, Cetrulo CL, Austen WG, Ott HC Tissue engineering. Part A 28323545 Tissue Eng Part A 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28323545
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Quantitative analysis of molecular transport across liposomal bilayer by J-mediated 13C Overhauser dynamic nuclear polarization. Cheng CY, Goor OJ, Han S Analytical chemistry 23072518 Anal Chem 2012 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/23072518
Correlating steric hydration forces with water dynamics through surface force and diffusion NMR measurements in a lipid-DMSO-H2O system. Schrader AM, Donaldson SH Jr, Song J, Cheng CY, Lee DW, Han S, Israelachvili JN Proceedings of the National Academy of Sciences of the United States of America 26261313 Proc Natl Acad Sci U S A 2015 Aug 25 https://www.ncbi.nlm.nih.gov/pubmed/26261313
Cholesterol enhances surface water diffusion of phospholipid bilayers. Cheng CY, Olijve LL, Kausik R, Han S The Journal of chemical physics 25494784 J Chem Phys 2014 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/25494784
Functional consequences of the oligomeric assembly of proteorhodopsin. Hussain S, Kinnebrew M, Schonenbach NS, Aye E, Han S Journal of molecular biology 25597999 J Mol Biol 2015 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/25597999
Dynamic nuclear polarization methods in solids and solutions to explore membrane proteins and membrane systems. Cheng CY, Han S Annual review of physical chemistry 23331309 Annu Rev Phys Chem 2013 https://www.ncbi.nlm.nih.gov/pubmed/23331309
Probing water density and dynamics in the chaperonin GroEL cavity. Franck JM, Sokolovski M, Kessler N, Matalon E, Gordon-Grossman M, Han SI, Goldfarb D, Horovitz A Journal of the American Chemical Society 24888581 J Am Chem Soc 2014 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/24888581
Nanometer-scale water- and proton-diffusion heterogeneities across water channels in polymer electrolyte membranes. Song J, Han OH, Han S Angewandte Chemie (International ed. in English) 25630609 Angew Chem Int Ed Engl 2015 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/25630609
Ion specific effects: decoupling ion-ion and ion-water interactions. Song J, Kang TH, Kim MW, Han S Physical chemistry chemical physics : PCCP 25761273 Phys Chem Chem Phys 2015 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/25761273
Anomalously Rapid Hydration Water Diffusion Dynamics Near DNA Surfaces. Franck JM, Ding Y, Stone K, Qin PZ, Han S Journal of the American Chemical Society 26256693 J Am Chem Soc 2015 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/26256693
Temporal and fluoride control of secondary metabolism regulates cellular organofluorine biosynthesis. Walker MC, Wen M, Weeks AM, Chang MC ACS chemical biology 22769062 ACS Chem Biol 2012 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/22769062
Molecular recognition of fluorine impacts substrate selectivity in the fluoroacetyl-CoA thioesterase FlK. Weeks AM, Keddie NS, Wadoux RD, O'Hagan D, Chang MC Biochemistry 24635371 Biochemistry 2014 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/24635371
Synthetic biology approaches to fluorinated polyketides. Thuronyi BW, Chang MC Accounts of chemical research 25719427 Acc Chem Res 2015 Mar 17 https://www.ncbi.nlm.nih.gov/pubmed/25719427
Editorial overview: Opportunities and challenges in synthetic biology. Chang MC, Zhao H Current opinion in chemical biology 26456417 Curr Opin Chem Biol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26456417
Natural and engineered biosynthesis of fluorinated natural products. Walker MC, Chang MC Chemical Society reviews 24776946 Chem Soc Rev 2014 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/24776946
Catalytic control of enzymatic fluorine specificity. Weeks AM, Chang MC Proceedings of the National Academy of Sciences of the United States of America 23150553 Proc Natl Acad Sci U S A 2012 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/23150553
Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways. Walker MC, Thuronyi BW, Charkoudian LK, Lowry B, Khosla C, Chang MC Science (New York, N.Y.) 24009388 Science 2013 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/24009388
Constructing de novo biosynthetic pathways for chemical synthesis inside living cells. Weeks AM, Chang MC Biochemistry 21591680 Biochemistry 2011 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/21591680
Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity. Weeks AM, Coyle SM, Jinek M, Doudna JA, Chang MC Biochemistry 20836570 Biochemistry 2010 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/20836570
Elucidating the mechanism of fluorinated extender unit loading for improved production of fluorine-containing polyketides. Ad O, Thuronyi BW, Chang MC Proceedings of the National Academy of Sciences of the United States of America 28096394 Proc Natl Acad Sci U S A 2017 Jan 31 https://www.ncbi.nlm.nih.gov/pubmed/28096394
Fluorophore and dye-assisted dispersion of carbon nanotubes in aqueous solution. Koh B, Kim G, Yoon HK, Park JB, Kopelman R, Cheng W Langmuir : the ACS journal of surfaces and colloids 22812904 Langmuir 2012 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/22812904
Detection of single fluorescent proteins inside eukaryotic cells using two-photon fluorescence. Hou X, Cheng W Biomedical optics express 22312586 Biomed Opt Express 2012 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/22312586
Mechanisms of carbon nanotube aggregation and the reversion of carbon nanotube aggregates in aqueous medium. Koh B, Cheng W Langmuir : the ACS journal of surfaces and colloids 25144606 Langmuir 2014 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/25144606
Mechanisms of HCV NS3 helicase monitored by optical tweezers. Cheng W Methods in molecular biology (Clifton, N.J.) 25579590 Methods Mol Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25579590
The Density Code for the Development of a Vaccine? Cheng W Journal of pharmaceutical sciences 27649885 J Pharm Sci 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27649885
Microfluidic-based high-throughput optical trapping of nanoparticles. Kotnala A, Zheng Y, Fu J, Cheng W Lab on a chip 28561826 Lab Chip 2017 Jun 13 https://www.ncbi.nlm.nih.gov/pubmed/28561826
Optical manipulation of a single human virus for study of viral-cell interactions. Hou X, DeSantis MC, Tian C, Cheng W Proceedings of SPIE--the International Society for Optical Engineering 27746582 Proc SPIE Int Soc Opt Eng 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27746582
Reversible aggregation of HIV-1 Gag proteins mediated by nucleic acids. Chen Z, Cheng W Biochemical and biophysical research communications 27965093 Biochem Biophys Res Commun 2017 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/27965093
Optical trapping of individual human immunodeficiency viruses in culture fluid reveals heterogeneity with single-molecule resolution. Pang Y, Song H, Kim JH, Hou X, Cheng W Nature nanotechnology 25038779 Nat Nanotechnol 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/25038779
Probability of Immobilization on Host Cell Surface Regulates Viral Infectivity. DeSantis MC, Tian C, Kim JH, Austin JL, Cheng W Physical review letters 33016741 Phys Rev Lett 2020 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/33016741
Optimized Infectivity of the Cell-Free Single-Cycle Human Immunodeficiency Viruses Type 1 (HIV-1) and Its Restriction by Host Cells. Kim JH, Song H, Austin JL, Cheng W PloS one 23825637 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23825637
Label-free detection and manipulation of single biological nanoparticles. DeSantis MC, Cheng W Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 26846164 Wiley Interdiscip Rev Nanomed Nanobiotechnol 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/26846164
Using optical trap to measure the refractive index of a single animal virus in culture fluid with high precision. Pang Y, Song H, Cheng W Biomedical optics express 27231613 Biomed Opt Express 2016 May 1 https://www.ncbi.nlm.nih.gov/pubmed/27231613
Dynasore inhibition on productive infection of HIV-1 in commonly used cell lines is independent of transferrin endocytosis. Song H, DeSantis M, Tian C, Cheng W Matters 31058179 Matters (Zur) 2018 https://www.ncbi.nlm.nih.gov/pubmed/31058179
Quantitation and Stability of Protein Conjugation on Liposomes for Controlled Density of Surface Epitopes. Chen Z, Moon JJ, Cheng W Bioconjugate chemistry 29528624 Bioconjug Chem 2018 Apr 18 https://www.ncbi.nlm.nih.gov/pubmed/29528624
Step detection in single-molecule real time trajectories embedded in correlated noise. Arunajadai SG, Cheng W PloS one 23533612 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23533612
Quantitative Correlation between Infectivity and Gp120 Density on HIV-1 Virions Revealed by Optical Trapping Virometry. DeSantis MC, Kim JH, Song H, Klasse PJ, Cheng W The Journal of biological chemistry 27129237 J Biol Chem 2016 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/27129237
The Single-Molecule Centroid Localization Algorithm Improves the Accuracy of Fluorescence Binding Assays. Hua B, Wang Y, Park S, Han KY, Singh D, Kim JH, Cheng W, Ha T Biochemistry 29457977 Biochemistry 2018 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/29457977
Electrowetting-driven variable-focus microlens on flexible surfaces. Li C, Jiang H Applied physics letters 22904571 Appl Phys Lett 2012 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/22904571
One-step femtosecond laser patterning of light-trapping structure on dye-sensitized solar cell photoelectrodes†. Zhang X, Liu H, Huang X, Jiang H Journal of materials chemistry. C 26113977 J Mater Chem C Mater 2015 Apr 14 https://www.ncbi.nlm.nih.gov/pubmed/26113977
Photovoltaically Self-Charging Cells with WO(3)·H(2)O/CNTs/PVDF Composite. Huang X, Zhang X, Jiang H RSC advances 27774146 RSC Adv 2016 https://www.ncbi.nlm.nih.gov/pubmed/27774146
Dye-sensitized solar cell with energy storage function through PVDF/ZnO nanocomposite counter electrode. Zhang X, Huang X, Li C, Jiang H Advanced materials (Deerfield Beach, Fla.) 23740719 Adv Mater 2013 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/23740719
Scattering-layer-induced energy storage function in polymer-based quasi-solid-state dye-sensitized solar cells. Zhang X, Jiang H Applied physics letters 25829547 Appl Phys Lett 2015 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/25829547
Artificial eye for scotopic vision with bioinspired all-optical photosensitivity enhancer. Liu H, Huang Y, Jiang H Proceedings of the National Academy of Sciences of the United States of America 26976565 Proc Natl Acad Sci U S A 2016 Apr 12 https://www.ncbi.nlm.nih.gov/pubmed/26976565
Tunable dielectric liquid lens on flexible substrate. Lu YS, Tu H, Xu Y, Jiang H Applied physics letters 24493877 Appl Phys Lett 2013 Dec 23 https://www.ncbi.nlm.nih.gov/pubmed/24493877
Actuators based on liquid crystalline elastomer materials. Jiang H, Li C, Huang X Nanoscale 23648966 Nanoscale 2013 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/23648966
Design and fabrication of an electrohydrodynamically actuated microlens with areal density modulated electrodes. Ashtiani AO, Jiang H Journal of micromechanics and microengineering : structures, devices, and systems 32773966 J Micromech Microeng 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/32773966
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High Performance All-Solid-State Flexible Micro-Pseudocapacitor Based on Hierarchically Nanostructured Tungsten Trioxide Composite. Huang X, Liu H, Zhang X, Jiang H ACS applied materials & interfaces 26618406 ACS Appl Mater Interfaces 2015 Dec 23 https://www.ncbi.nlm.nih.gov/pubmed/26618406
Lateral dye-sensitized microscale solar cells via femtosecond laser patterning. Zhang X, Huang Y, Hao B, Hewei L, Huang X, Jiang H Advanced materials technologies 31341947 Adv Mater Technol 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/31341947
Double Sided-Design of Electrodes Driving Tunable Dielectrophoretic Miniature Lens. Almoallem Y, Jiang H Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems 29606846 J Microelectromech Syst 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/29606846
Liquid Tunable Microlenses based on MEMS techniques. Zeng X, Jiang H Journal of physics D: Applied physics 24163480 J Phys D Appl Phys 2013 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/24163480
Recovering degraded quasi-solid-state dye-sensitized solar cells by applying electrical pulses. Zhang X, Huang X, Jiang H Physical chemistry chemical physics : PCCP 23545782 Phys Chem Chem Phys 2013 May 14 https://www.ncbi.nlm.nih.gov/pubmed/23545782
Energy Storage via Polyvinylidene Fluoride Dielectric on the Counterelectrode of Dye-Sensitized Solar Cells. Huang X, Zhang X, Jiang H Journal of power sources 24327797 J Power Sources 2014 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/24327797
Remote Axial Tuning in Microscopy Utilizing Hydrogel-Driven Tunable Liquid Lens. Kanhere A, Lin G, Jiang H Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems 31983867 J Microelectromech Syst 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/31983867
Fabrication and Characterization of Flexible Electrowetting on Dielectrics (EWOD) Microlens. Li C, Jiang H Micromachines 25360324 Micromachines (Basel) 2014 Jul 4 https://www.ncbi.nlm.nih.gov/pubmed/25360324
Tight regulation of plant immune responses by combining promoter and suicide exon elements. Gonzalez TL, Liang Y, Nguyen BN, Staskawicz BJ, Loqué D, Hammond MC Nucleic acids research 26138488 Nucleic Acids Res 2015 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/26138488
Structural basis for molecular discrimination by a 3',3'-cGAMP sensing riboswitch. Ren A, Wang XC, Kellenberger CA, Rajashankar KR, Jones RA, Hammond MC, Patel DJ Cell reports 25818298 Cell Rep 2015 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/25818298
Chemiluminescent Biosensors for Detection of Second Messenger Cyclic di-GMP. Dippel AB, Anderson WA, Evans RS, Deutsch S, Hammond MC ACS chemical biology 29466657 ACS Chem Biol 2018 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/29466657
Structure-guided design of fluorescent S-adenosylmethionine analogs for a high-throughput screen to target SAM-I riboswitch RNAs. Hickey SF, Hammond MC Chemistry & biology 24560607 Chem Biol 2014 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/24560607
Live Flow Cytometry Analysis of c-di-GMP Levels in Single Cell Populations. Yeo J, Wang XC, Hammond MC Methods in molecular biology (Clifton, N.J.) 28889290 Methods Mol Biol 2017 https://www.ncbi.nlm.nih.gov/pubmed/28889290
In Vitro and In Vivo Enzyme Activity Screening via RNA-Based Fluorescent Biosensors for S-Adenosyl-l-homocysteine (SAH). Su Y, Hickey SF, Keyser SG, Hammond MC Journal of the American Chemical Society 27191512 J Am Chem Soc 2016 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/27191512
Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-GMP (3', 3'-cGAMP). Hallberg ZF, Wang XC, Wright TA, Nan B, Ad O, Yeo J, Hammond MC Proceedings of the National Academy of Sciences of the United States of America 26839412 Proc Natl Acad Sci U S A 2016 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/26839412
An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway. Bose D, Su Y, Marcus A, Raulet DH, Hammond MC Cell chemical biology 27889408 Cell Chem Biol 2016 Dec 22 https://www.ncbi.nlm.nih.gov/pubmed/27889408
GEMM-I riboswitches from Geobacter sense the bacterial second messenger cyclic AMP-GMP. Kellenberger CA, Wilson SC, Hickey SF, Gonzalez TL, Su Y, Hallberg ZF, Brewer TF, Iavarone AT, Carlson HK, Hsieh YF, Hammond MC Proceedings of the National Academy of Sciences of the United States of America 25848022 Proc Natl Acad Sci U S A 2015 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/25848022
Microfluidic screening of electrophoretic mobility shifts elucidates riboswitch binding function. Karns K, Vogan JM, Qin Q, Hickey SF, Wilson SC, Hammond MC, Herr AE Journal of the American Chemical Society 23343213 J Am Chem Soc 2013 Feb 27 https://www.ncbi.nlm.nih.gov/pubmed/23343213
A minimalist biosensor: Quantitation of cyclic di-GMP using the conformational change of a riboswitch aptamer. Kellenberger CA, Sales-Lee J, Pan Y, Gassaway MM, Herr AE, Hammond MC RNA biology 26114964 RNA Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26114964
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING. Diner EJ, Burdette DL, Wilson SC, Monroe KM, Kellenberger CA, Hyodo M, Hayakawa Y, Hammond MC, Vance RE Cell reports 23707065 Cell Rep 2013 May 30 https://www.ncbi.nlm.nih.gov/pubmed/23707065
Next-generation RNA-based fluorescent biosensors enable anaerobic detection of cyclic di-GMP. Wang XC, Wilson SC, Hammond MC Nucleic acids research 27382070 Nucleic Acids Res 2016 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/27382070
RNA-Based Fluorescent Biosensors for Live Cell Imaging of Second Messenger Cyclic di-AMP. Kellenberger CA, Chen C, Whiteley AT, Portnoy DA, Hammond MC Journal of the American Chemical Society 25965978 J Am Chem Soc 2015 May 27 https://www.ncbi.nlm.nih.gov/pubmed/25965978
Live Cell Imaging Using Riboswitch-Spinach tRNA Fusions as Metabolite-Sensing Fluorescent Biosensors. Kellenberger CA, Hallberg ZF, Hammond MC Methods in molecular biology (Clifton, N.J.) 25967055 Methods Mol Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25967055
High-throughput electrophoretic mobility shift assays for quantitative analysis of molecular binding reactions. Pan Y, Duncombe TA, Kellenberger CA, Hammond MC, Herr AE Analytical chemistry 25233437 Anal Chem 2014 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/25233437
Engineering and In Vivo Applications of Riboswitches. Hallberg ZF, Su Y, Kitto RZ, Hammond MC Annual review of biochemistry 28375743 Annu Rev Biochem 2017 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/28375743
RNA-based fluorescent biosensors for live cell imaging of second messengers cyclic di-GMP and cyclic AMP-GMP. Kellenberger CA, Wilson SC, Sales-Lee J, Hammond MC Journal of the American Chemical Society 23488798 J Am Chem Soc 2013 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/23488798
Nutritional control of epigenetic processes in yeast and human cells. Sadhu MJ, Guan Q, Li F, Sales-Lee J, Iavarone AT, Hammond MC, Cande WZ, Rine J Genetics 23979574 Genetics 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/23979574
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In vitro analysis of riboswitch-Spinach aptamer fusions as metabolite-sensing fluorescent biosensors. Kellenberger CA, Hammond MC Methods in enzymology 25605385 Methods Enzymol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25605385
In Vivo Biochemistry: Single-Cell Dynamics of Cyclic Di-GMP in Escherichia coli in Response to Zinc Overload. Yeo J, Dippel AB, Wang XC, Hammond MC Biochemistry 29052983 Biochemistry 2018 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/29052983
Designing fluorescent biosensors using circular permutations of riboswitches. Truong J, Hsieh YF, Truong L, Jia G, Hammond MC Methods (San Diego, Calif.) 29458090 Methods 2018 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/29458090
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Gene duplication and co-evolution of G1/S transcription factor specificity in fungi are essential for optimizing cell fitness. Hendler A, Medina EM, Kishkevich A, Abu-Qarn M, Klier S, Buchler NE, de Bruin RAM, Aharoni A PLoS genetics 28505153 PLoS Genet 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28505153
BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells. Gómez-Schiavon M, Chen LF, West AE, Buchler NE Genome biology 28870226 Genome Biol 2017 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/28870226
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Cell cycle Start is coupled to entry into the yeast metabolic cycle across diverse strains and growth rates. Burnetti AJ, Aydin M, Buchler NE Molecular biology of the cell 26538026 Mol Biol Cell 2016 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/26538026
Redox rhythm reinforces the circadian clock to gate immune response. Zhou M, Wang W, Karapetyan S, Mwimba M, Marqués J, Buchler NE, Dong X Nature 26098366 Nature 2015 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/26098366
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Measuring fast gene dynamics in single cells with time-lapse luminescence microscopy. Mazo-Vargas A, Park H, Aydin M, Buchler NE Molecular biology of the cell 25232010 Mol Biol Cell 2014 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/25232010
Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes. Chen LF, Lin YT, Gallegos DA, Hazlett MF, Gómez-Schiavon M, Yang MG, Kalmeta B, Zhou AS, Holtzman L, Gersbach CA, Grandl J, Buchler NE, West AE Cell reports 30699347 Cell Rep 2019 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/30699347
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Efficient analysis of stochastic gene dynamics in the non-adiabatic regime using piecewise deterministic Markov processes. Lin YT, Buchler NE Journal of the Royal Society, Interface 29386401 J R Soc Interface 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29386401
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Experimental Analysis of Imprinted Mouse X-Chromosome Inactivation. Cloutier M, Harris C, Gayen S, Maclary E, Kalantry S Methods in molecular biology (Clifton, N.J.) 30218368 Methods Mol Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30218368
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MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency. Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Karatas H, Liu L, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y Cell stem cell 26996599 Cell Stem Cell 2016 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/26996599
Regulation of Sex-biased Gene Expression by the Ancestral X-Y Chromosomal Gene Pair Kdm5c-Kdm5d. Malcore RM, Samanta MK, Kalantry S, Iwase S bioRxiv : the preprint server for biology 39484414 bioRxiv 2024 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/39484414
Long nonoding RNAs in the X-inactivation center. Maclary E, Hinten M, Harris C, Kalantry S Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 24297756 Chromosome Res 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/24297756
Functional Dissection of the m6A RNA Modification. Huisman B, Manske G, Carney S, Kalantry S Trends in biochemical sciences 28063638 Trends Biochem Sci 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/28063638
Highly Resolved Detection of Long Non-coding RNAs In Situ. Trotter M, Harris C, Cloutier M, Samanta M, Kalantry S Methods in molecular biology (Clifton, N.J.) 34417748 Methods Mol Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34417748
Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells. Taniguchi K, Shao Y, Townshend RF, Tsai YH, DeLong CJ, Lopez SA, Gayen S, Freddo AM, Chue DJ, Thomas DJ, Spence JR, Margolis B, Kalantry S, Fu J, O'Shea KS, Gumucio DL Stem cell reports 26626176 Stem Cell Reports 2015 Dec 8 https://www.ncbi.nlm.nih.gov/pubmed/26626176
Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis. Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L, Rao A Proceedings of the National Academy of Sciences of the United States of America 26199412 Proc Natl Acad Sci U S A 2015 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/26199412
Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2. Harris C, Cloutier M, Trotter M, Hinten M, Gayen S, Du Z, Xie W, Kalantry S eLife 30938678 Elife 2019 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/30938678
Chromatin-enriched lncRNAs: a novel class of enhancer RNAs. Gayen S, Kalantry S Nature structural & molecular biology 28686230 Nat Struct Mol Biol 2017 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/28686230
Differentiation-dependent requirement of Tsix long non-coding RNA in imprinted X-chromosome inactivation. Maclary E, Buttigieg E, Hinten M, Gayen S, Harris C, Sarkar MK, Purushothaman S, Kalantry S Nature communications 24979243 Nat Commun 2014 Jun 30 https://www.ncbi.nlm.nih.gov/pubmed/24979243
Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. Jiao B, Ma H, Shokhirev MN, Drung A, Yang Q, Shin J, Lu S, Byron M, Kalantry S, Mercurio AM, Lawrence JB, Hoffmann A, Bach I Cell 22541433 Cell 2012 Apr 27 https://www.ncbi.nlm.nih.gov/pubmed/22541433
PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes. Kang J, Kalantry S, Rao A Cell research 22868271 Cell Res 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/22868271
A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance. Ku CJ, Lim KC, Kalantry S, Maillard I, Engel JD, Hosoya T Genes & development 26385963 Genes Dev 2015 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/26385963
Mary Lyon: A Tribute. Kalantry S, Mueller JL American journal of human genetics 26713337 Am J Hum Genet 2015 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/26713337
The central role of EED in the orchestration of polycomb group complexes. Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, Poliakov A, Yocum AK, Li Y, Chen W, Cao X, Jiang X, Dahiya A, Harris C, Feng FY, Kalantry S, Qin ZS, Dhanasekaran SM, Chinnaiyan AM Nature communications 24457600 Nat Commun 2014 https://www.ncbi.nlm.nih.gov/pubmed/24457600
An Xist-activating antisense RNA required for X-chromosome inactivation. Sarkar MK, Gayen S, Kumar S, Maclary E, Buttigieg E, Hinten M, Kumari A, Harris C, Sado T, Kalantry S Nature communications 26477563 Nat Commun 2015 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/26477563
Visualizing Long Noncoding RNAs on Chromatin. Hinten M, Maclary E, Gayen S, Harris C, Kalantry S Methods in molecular biology (Clifton, N.J.) 26721489 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/26721489
PRC2 represses transcribed genes on the imprinted inactive X chromosome in mice. Maclary E, Hinten M, Harris C, Sethuraman S, Gayen S, Kalantry S Genome biology 28468635 Genome Biol 2017 May 3 https://www.ncbi.nlm.nih.gov/pubmed/28468635
An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells. Taniguchi K, Shao Y, Townshend RF, Cortez CL, Harris CE, Meshinchi S, Kalantry S, Fu J, O'Shea KS, Gumucio DL The Journal of cell biology 29021220 J Cell Biol 2017 Dec 4 https://www.ncbi.nlm.nih.gov/pubmed/29021220
Phonetic feature encoding in human superior temporal gyrus. Mesgarani N, Cheung C, Johnson K, Chang EF Science (New York, N.Y.) 24482117 Science 2014 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/24482117
The Control of Vocal Pitch in Human Laryngeal Motor Cortex. Dichter BK, Breshears JD, Leonard MK, Chang EF Cell 29958109 Cell 2018 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/29958109
Encoding of Articulatory Kinematic Trajectories in Human Speech Sensorimotor Cortex. Chartier J, Anumanchipalli GK, Johnson K, Chang EF Neuron 29779940 Neuron 2018 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/29779940
Real-time classification of auditory sentences using evoked cortical activity in humans. Moses DA, Leonard MK, Chang EF Journal of neural engineering 29378977 J Neural Eng 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29378977
Control of spoken vowel acoustics and the influence of phonetic context in human speech sensorimotor cortex. Bouchard KE, Chang EF The Journal of neuroscience : the official journal of the Society for Neuroscience 25232105 J Neurosci 2014 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/25232105
Are preoperative chlorhexidine gluconate showers associated with a reduction in surgical site infection following craniotomy? A retrospective cohort analysis of 3126 surgical procedures. Ammanuel SG, Edwards CS, Chan AK, Mummaneni PV, Kidane J, Vargas E, D'Souza S, Nichols AD, Sankaran S, Abla AA, Aghi MK, Chang EF, Hervey-Jumper SL, Kunwar S, Larson PS, Lawton MT, Starr PA, Theodosopoulos PV, Berger MS, McDermott MW Journal of neurosurgery 33930864 J Neurosurg 2021 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/33930864
Inhibitory control of speech production in the human premotor frontal cortex. Zhao L, Silva AB, Kurteff GL, Chang EF Nature human behaviour 40033133 Nat Hum Behav 2025 Mar 3 https://www.ncbi.nlm.nih.gov/pubmed/40033133
Speech map in the human ventral sensory-motor cortex. Conant D, Bouchard KE, Chang EF Current opinion in neurobiology 24492080 Curr Opin Neurobiol 2014 Feb https://www.ncbi.nlm.nih.gov/pubmed/24492080
Persistent neuronal activity in human prefrontal cortex links perception and action. Haller M, Case J, Crone NE, Chang EF, King-Stephens D, Laxer KD, Weber PB, Parvizi J, Knight RT, Shestyuk AY Nature human behaviour 29963646 Nat Hum Behav 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29963646
Contemporary model of language organization: an overview for neurosurgeons. Chang EF, Raygor KP, Berger MS Journal of neurosurgery 25423277 J Neurosurg 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25423277
The peri-Sylvian cortical network underlying single word repetition revealed by electrocortical stimulation and direct neural recordings. Leonard MK, Cai R, Babiak MC, Ren A, Chang EF Brain and language 27450996 Brain Lang 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/27450996
The influence of lexical statistics on temporal lobe cortical dynamics during spoken word listening. Cibelli ES, Leonard MK, Johnson K, Chang EF Brain and language 26072003 Brain Lang 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26072003
Neural speech recognition: continuous phoneme decoding using spatiotemporal representations of human cortical activity. Moses DA, Mesgarani N, Leonard MK, Chang EF Journal of neural engineering 27484713 J Neural Eng 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27484713
Cortical Encoding of Manual Articulatory and Linguistic Features in American Sign Language. Leonard MK, Lucas B, Blau S, Corina DP, Chang EF Current biology : CB 32888480 Curr Biol 2020 Nov 16 https://www.ncbi.nlm.nih.gov/pubmed/32888480
Human cortical sensorimotor network underlying feedback control of vocal pitch. Chang EF, Niziolek CA, Knight RT, Nagarajan SS, Houde JF Proceedings of the National Academy of Sciences of the United States of America 23345447 Proc Natl Acad Sci U S A 2013 Feb 12 https://www.ncbi.nlm.nih.gov/pubmed/23345447
Speech synthesis from neural decoding of spoken sentences. Anumanchipalli GK, Chartier J, Chang EF Nature 31019317 Nature 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/31019317
Functional organization of human sensorimotor cortex for speech articulation. Bouchard KE, Mesgarani N, Johnson K, Chang EF Nature 23426266 Nature 2013 Mar 21 https://www.ncbi.nlm.nih.gov/pubmed/23426266
Syllabic (∼2-5 Hz) and fluctuation (∼1-10 Hz) ranges in speech and auditory processing. Edwards E, Chang EF Hearing research 24035819 Hear Res 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/24035819
Transient aphasias after left hemisphere resective surgery. Wilson SM, Lam D, Babiak MC, Perry DW, Shih T, Hess CP, Berger MS, Chang EF Journal of neurosurgery 26115463 J Neurosurg 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26115463
Arresting a Torsin ATPase reshapes the endoplasmic reticulum. Rose AE, Zhao C, Turner EM, Steyer AM, Schlieker C The Journal of biological chemistry 24275647 J Biol Chem 2014 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/24275647
Regulation of Torsin ATPases by LAP1 and LULL1. Zhao C, Brown RS, Chase AR, Eisele MR, Schlieker C Proceedings of the National Academy of Sciences of the United States of America 23569223 Proc Natl Acad Sci U S A 2013 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/23569223
The mechanism of Torsin ATPase activation. Brown RS, Zhao C, Chase AR, Wang J, Schlieker C Proceedings of the National Academy of Sciences of the United States of America 25352667 Proc Natl Acad Sci U S A 2014 Nov 11 https://www.ncbi.nlm.nih.gov/pubmed/25352667
Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum (ER) in Response to ER Stress and B Cell Stimulation. Zhao C, Brown RS, Tang CH, Hu CC, Schlieker C The Journal of biological chemistry 26953341 J Biol Chem 2016 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/26953341
Torsin ATPases: structural insights and functional perspectives. Laudermilch E, Schlieker C Current opinion in cell biology 26803745 Curr Opin Cell Biol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/26803745
The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations. Tsai PL, Zhao C, Turner E, Schlieker C eLife 27336722 Elife 2016 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/27336722
The Torsin Activator LULL1 Is Required for Efficient Growth of Herpes Simplex Virus 1. Turner EM, Brown RS, Laudermilch E, Tsai PL, Schlieker C Journal of virology 26041288 J Virol 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26041288
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Dissecting Torsin/cofactor function at the nuclear envelope: a genetic study. Laudermilch E, Tsai PL, Graham M, Turner E, Zhao C, Schlieker C Molecular biology of the cell 27798237 Mol Biol Cell 2016 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/27798237
Alternative nuclear transport for cellular protein quality control. Rose A, Schlieker C Trends in cell biology 22858153 Trends Cell Biol 2012 Oct https://www.ncbi.nlm.nih.gov/pubmed/22858153
Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle. Little HC, Tan SY, Cali FM, Rodriguez S, Lei X, Wolfe A, Hug C, Wong GW Molecular & cellular proteomics : MCP 29735541 Mol Cell Proteomics 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29735541
Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice. Kasahara DI, Kim HY, Mathews JA, Verbout NG, Williams AS, Wurmbrand AP, Ninin FM, Neto FL, Benedito LA, Hug C, Umetsu DT, Shore SA American journal of physiology. Lung cellular and molecular physiology 24381131 Am J Physiol Lung Cell Mol Physiol 2014 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/24381131
Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. Furuse Y, Finethy R, Saka HA, Xet-Mull AM, Sisk DM, Smith KL, Lee S, Coers J, Valdivia RH, Tobin DM, Cullen BR PloS one 25184567 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/25184567
Interception of host angiogenic signalling limits mycobacterial growth. Oehlers SH, Cronan MR, Scott NR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS, Tobin DM Nature 25470057 Nature 2015 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/25470057
Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases. McClean CM, Tobin DM Pathogens and disease 27402783 Pathog Dis 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27402783
Infection-Induced Vascular Permeability Aids Mycobacterial Growth. Oehlers SH, Cronan MR, Beerman RW, Johnson MG, Huang J, Kontos CD, Stout JE, Tobin DM The Journal of infectious diseases 27496976 J Infect Dis 2017 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/27496976
The Macrophage-Specific Promoter mfap4 Allows Live, Long-Term Analysis of Macrophage Behavior during Mycobacterial Infection in Zebrafish. Walton EM, Cronan MR, Beerman RW, Tobin DM PloS one 26445458 PLoS One 2015 https://www.ncbi.nlm.nih.gov/pubmed/26445458
CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections. Cronan MR, Rosenberg AF, Oehlers SH, Saelens JW, Sisk DM, Jurcic Smith KL, Lee S, Tobin DM Disease models & mechanisms 26449262 Dis Model Mech 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26449262
Epigenetic control of intestinal barrier function and inflammation in zebrafish. Marjoram L, Alvers A, Deerhake ME, Bagwell J, Mankiewicz J, Cocchiaro JL, Beerman RW, Willer J, Sumigray KD, Katsanis N, Tobin DM, Rawls JF, Goll MG, Bagnat M Proceedings of the National Academy of Sciences of the United States of America 25730872 Proc Natl Acad Sci U S A 2015 Mar 3 https://www.ncbi.nlm.nih.gov/pubmed/25730872
TB: the Yin and Yang of lipid mediators. Tobin DM, Ramakrishnan L Current opinion in pharmacology 23849093 Curr Opin Pharmacol 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23849093
CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. Wang L, Oehlers SH, Espenschied ST, Rawls JF, Tobin DM, Ko DC Genome biology 26374098 Genome Biol 2015 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/26374098
Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. Cronan MR, Beerman RW, Rosenberg AF, Saelens JW, Johnson MG, Oehlers SH, Sisk DM, Jurcic Smith KL, Medvitz NA, Miller SE, Trinh LA, Fraser SE, Madden JF, Turner J, Stout JE, Lee S, Tobin DM Immunity 27760340 Immunity 2016 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/27760340
Host-Directed Therapies for Tuberculosis. Tobin DM Cold Spring Harbor perspectives in medicine 25986592 Cold Spring Harb Perspect Med 2015 May 18 https://www.ncbi.nlm.nih.gov/pubmed/25986592
Adventures within the speckled band: heterogeneity, angiogenesis, and balanced inflammation in the tuberculous granuloma. Matty MA, Roca FJ, Cronan MR, Tobin DM Immunological reviews 25703566 Immunol Rev 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25703566
Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion. Tenor JL, Oehlers SH, Yang JL, Tobin DM, Perfect JR mBio 26419880 mBio 2015 Sep 29 https://www.ncbi.nlm.nih.gov/pubmed/26419880
Zebrafish: a see-through host and a fluorescent toolbox to probe host-pathogen interaction. Tobin DM, May RC, Wheeler RT PLoS pathogens 22241986 PLoS Pathog 2012 Jan https://www.ncbi.nlm.nih.gov/pubmed/22241986
Live Imaging of Host-Pathogen Interactions in Zebrafish Larvae. Matty MA, Oehlers SH, Tobin DM Methods in molecular biology (Clifton, N.J.) 27464810 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/27464810
Drug-Inducible, Cell-Specific Manipulation of Intracellular Calcium in Zebrafish Through Mammalian TRPV1 Expression. Matty MA, Beerman RW, Tobin DM Zebrafish 27058231 Zebrafish 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27058231
An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection. Tobin DM, Roca FJ, Ray JP, Ko DC, Ramakrishnan L PloS one 23874453 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23874453
Fit for consumption: zebrafish as a model for tuberculosis. Cronan MR, Tobin DM Disease models & mechanisms 24973748 Dis Model Mech 2014 Jul https://www.ncbi.nlm.nih.gov/pubmed/24973748
Direct In Vivo Manipulation and Imaging of Calcium Transients in Neutrophils Identify a Critical Role for Leading-Edge Calcium Flux. Beerman RW, Matty MA, Au GG, Looger LL, Choudhury KR, Keller PJ, Tobin DM Cell reports 26673320 Cell Rep 2015 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/26673320
Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration. Berg RD, Levitte S, O'Sullivan MP, O'Leary SM, Cambier CJ, Cameron J, Takaki KK, Moens CB, Tobin DM, Keane J, Ramakrishnan L Cell 27015311 Cell 2016 Mar 24 https://www.ncbi.nlm.nih.gov/pubmed/27015311
Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TT, Vary JC, Hawn TR, Dunstan SJ, Farrar JJ, Thwaites GE, King MC, Serhan CN, Ramakrishnan L Cell 22304914 Cell 2012 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/22304914
Thrombocyte Inhibition Restores Protective Immunity to Mycobacterial Infection in Zebrafish. Hortle E, Johnson KE, Johansen MD, Nguyen T, Shavit JA, Britton WJ, Tobin DM, Oehlers SH The Journal of infectious diseases 30877311 J Infect Dis 2019 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/30877311
All signals lost. Wilke KE, Carlson EE Science translational medicine 24048521 Sci Transl Med 2013 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/24048521
Mechanistic Studies of Bioorthogonal ATP Analogues for Assessment of Histidine Kinase Autophosphorylation. Espinasse A, Wen X, Goodpaster JD, Carlson EE ACS chemical biology 32043868 ACS Chem Biol 2020 May 15 https://www.ncbi.nlm.nih.gov/pubmed/32043868
Disarming the virulence arsenal of Pseudomonas aeruginosa by blocking two-component system signaling. Goswami M, Espinasse A, Carlson EE Chemical science 30542536 Chem Sci 2018 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/30542536
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases. Goswami M, Wilke KE, Carlson EE Journal of medicinal chemistry 28933546 J Med Chem 2017 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/28933546
Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition. Wilke KE, Fihn CA, Carlson EE Bioorganic & medicinal chemistry 29706527 Bioorg Med Chem 2018 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/29706527
Exploration of the Effects of γ-Phosphate-Modified ATP Analogues on Histidine Kinase Autophosphorylation. Chase OM, Espinasse A, Wilke KE, Carlson EE Biochemistry 29944360 Biochemistry 2018 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/29944360
Profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39. Kocaoglu O, Tsui HC, Winkler ME, Carlson EE Antimicrobial agents and chemotherapy 25845878 Antimicrob Agents Chemother 2015 https://www.ncbi.nlm.nih.gov/pubmed/25845878
Chemoselective hydroxyl group transformation: an elusive target. Trader DJ, Carlson EE Molecular bioSystems 22695722 Mol Biosyst 2012 Oct https://www.ncbi.nlm.nih.gov/pubmed/22695722
Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division. Kocaoglu O, Calvo RA, Sham LT, Cozy LM, Lanning BR, Francis S, Winkler ME, Kearns DB, Carlson EE ACS chemical biology 22909777 ACS Chem Biol 2012 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/22909777
Thiol-ene enabled detection of thiophosphorylated kinase substrates. Garber KC, Carlson EE ACS chemical biology 23668631 ACS Chem Biol 2013 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/23668631
Mechanistic insight into inhibition of two-component system signaling. Francis S, Wilke KE, Brown DE, Carlson EE MedChemComm 23336064 Medchemcomm 2013 https://www.ncbi.nlm.nih.gov/pubmed/23336064
2-Aminobenzothiazoles Inhibit Virulence Gene Expression and Block Polymyxin Resistance in Salmonella enterica. Thielen MK, Vaneerd CK, Goswami M, Carlson EE, May JF Chembiochem : a European journal of chemical biology 32750193 Chembiochem 2020 Dec 11 https://www.ncbi.nlm.nih.gov/pubmed/32750193
Targeting multidrug resistant Staphylococcus infections with bacterial histidine kinase inhibitors. Espinasse A, Goswami M, Yang J, Vorasin O, Ji Y, Carlson EE Chemical science 37206395 Chem Sci 2023 May 17 https://www.ncbi.nlm.nih.gov/pubmed/37206395
Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumoniae D39. Tsui HT, Boersma MJ, Vella SA, Kocaoglu O, Kuru E, Peceny JK, Carlson EE, VanNieuwenhze MS, Brun YV, Shaw SL, Winkler ME Molecular microbiology 25099088 Mol Microbiol 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25099088
Progress and prospects for small-molecule probes of bacterial imaging. Kocaoglu O, Carlson EE Nature chemical biology 27315537 Nat Chem Biol 2016 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/27315537
Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39. Land AD, Tsui HC, Kocaoglu O, Vella SA, Shaw SL, Keen SK, Sham LT, Carlson EE, Winkler ME Molecular microbiology 24118410 Mol Microbiol 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/24118410
Penicillin-binding protein imaging probes. Kocaoglu O, Carlson EE Current protocols in chemical biology 24391095 Curr Protoc Chem Biol 2013 https://www.ncbi.nlm.nih.gov/pubmed/24391095
Thiol-ene-Enabled Detection of Thiophosphorylation as a Labeling Strategy for Phosphoproteins. Wilke KE, Carlson EE Methods in molecular biology (Clifton, N.J.) 26584915 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/26584915
Profiling of β-lactam selectivity for penicillin-binding proteins in Escherichia coli strain DC2. Kocaoglu O, Carlson EE Antimicrobial agents and chemotherapy 25733506 Antimicrob Agents Chemother 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25733506
Activity-based probe for histidine kinase signaling. Wilke KE, Francis S, Carlson EE Journal of the American Chemical Society 22606938 J Am Chem Soc 2012 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/22606938
Harnessing β-Lactam Antibiotics for Illumination of the Activity of Penicillin-Binding Proteins in Bacillus subtilis. Sharifzadeh S, Dempwolff F, Kearns DB, Carlson EE ACS chemical biology 32155044 ACS Chem Biol 2020 May 15 https://www.ncbi.nlm.nih.gov/pubmed/32155044
Inactivation of multiple bacterial histidine kinases by targeting the ATP-binding domain. Wilke KE, Francis S, Carlson EE ACS chemical biology 25531939 ACS Chem Biol 2015 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/25531939
Novel Electrophilic Scaffold for Imaging of Essential Penicillin-Binding Proteins in Streptococcus pneumoniae. Sharifzadeh S, Boersma MJ, Kocaoglu O, Shokri A, Brown CL, Shirley JD, Winkler ME, Carlson EE ACS chemical biology 28990753 ACS Chem Biol 2017 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/28990753
Equilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics. Pan L, Aller SG Scientific reports 25600711 Sci Rep 2015 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/25600711
In vitro evolution and affinity-maturation with Coliphage qβ display. Skamel C, Aller SG, Bopda Waffo A PloS one 25393763 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/25393763
Refined structures of mouse P-glycoprotein. Li J, Jaimes KF, Aller SG Protein science : a publication of the Protein Society 24155053 Protein Sci 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/24155053
Tools and procedures for visualization of proteins and other biomolecules. Pan L, Aller SG Current protocols in molecular biology 25827086 Curr Protoc Mol Biol 2015 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/25827086
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA Nature methods 26501517 Nat Methods 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26501517
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Pentobra: A Potent Antibiotic with Multiple Layers of Selective Antimicrobial Mechanisms against Propionibacterium Acnes. Schmidt NW, Agak GW, Deshayes S, Yu Y, Blacker A, Champer J, Xian W, Kasko AM, Kim J, Wong GCL The Journal of investigative dermatology 25668237 J Invest Dermatol 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25668237
Complex dynamic substrate control: dual-tone hydrogel photoresists allow double-dissociation of topography and modulus. Xue C, Wong DY, Kasko AM Advanced materials (Deerfield Beach, Fla.) 24339260 Adv Mater 2014 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/24339260
Photodegradable macromers and hydrogels for live cell encapsulation and release. Griffin DR, Kasko AM Journal of the American Chemical Society 22765384 J Am Chem Soc 2012 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/22765384
Photo-selective delivery of model therapeutics from hydrogels. Griffin DR, Kasko AM ACS macro letters 25285242 ACS Macro Lett 2012 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/25285242
Low-Dose, Long-Wave UV Light Does Not Affect Gene Expression of Human Mesenchymal Stem Cells. Wong DY, Ranganath T, Kasko AM PloS one 26418040 PLoS One 2015 https://www.ncbi.nlm.nih.gov/pubmed/26418040
Synthesis of photodegradable macromers for conjugation and release of bioactive molecules. Griffin DR, Schlosser JL, Lam SF, Nguyen TH, Maynard HD, Kasko AM Biomacromolecules 23506440 Biomacromolecules 2013 Apr 8 https://www.ncbi.nlm.nih.gov/pubmed/23506440
Shape-Changing Photodegradable Hydrogels for Dynamic 3D Cell Culture. Käpylä E, Delgado SM, Kasko AM ACS applied materials & interfaces 27322508 ACS Appl Mater Interfaces 2016 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/27322508
Aptamer Recognition of Multiplexed Small-Molecule-Functionalized Substrates. Nakatsuka N, Cao HH, Deshayes S, Melkonian AL, Kasko AM, Weiss PS, Andrews AM ACS applied materials & interfaces 29851335 ACS Appl Mater Interfaces 2018 Jul 18 https://www.ncbi.nlm.nih.gov/pubmed/29851335
Magnetic field activated drug delivery using thermodegradable azo-functionalised PEG-coated core-shell mesoporous silica nanoparticles. Saint-Cricq P, Deshayes S, Zink JI, Kasko AM Nanoscale 26181577 Nanoscale 2015 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/26181577
Single-cell systems biology by super-resolution imaging and combinatorial labeling. Lubeck E, Cai L Nature methods 22660740 Nat Methods 2012 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/22660740
Turning single cells into microarrays by super-resolution barcoding. Cai L Briefings in functional genomics 23178478 Brief Funct Genomics 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23178478
In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus. Shah S, Lubeck E, Zhou W, Cai L Neuron 27764670 Neuron 2016 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/27764670
Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing. Shah S, Lubeck E, Schwarzkopf M, He TF, Greenbaum A, Sohn CH, Lignell A, Choi HM, Gradinaru V, Pierce NA, Cai L Development (Cambridge, England) 27342713 Development 2016 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/27342713
Identification of a neural crest stem cell niche by Spatial Genomic Analysis. Lignell A, Kerosuo L, Streichan SJ, Cai L, Bronner ME Nature communications 29184067 Nat Commun 2017 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/29184067
Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA. Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, Hughes C, Fonseca-Pereira D, Veiga-Fernandes H, Raj A, Kambayashi T, Brodsky IE, O'Shea JJ, Wherry EJ, Goff LA, Rinn JL, Williams A, Flavell RA, Henao-Mejia J Immunity 28930659 Immunity 2017 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/28930659
Intercellular mRNA trafficking via membrane nanotube-like extensions in mammalian cells. Haimovich G, Ecker CM, Dunagin MC, Eggan E, Raj A, Gerst JE, Singer RH Proceedings of the National Academy of Sciences of the United States of America 29078295 Proc Natl Acad Sci U S A 2017 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/29078295
Half dozen of one, six billion of the other: What can small- and large-scale molecular systems biology learn from one another? Mellis IA, Raj A Genome research 26430156 Genome Res 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26430156
Visualizing allele-specific expression in single cells reveals epigenetic mosaicism in an H19 loss-of-imprinting mutant. Ginart P, Kalish JM, Jiang CL, Yu AC, Bartolomei MS, Raj A Genes & development 26944681 Genes Dev 2016 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/26944681
What's Luck Got to Do with It: Single Cells, Multiple Fates, and Biological Nondeterminism. Symmons O, Raj A Molecular cell 27259209 Mol Cell 2016 Jun 2 https://www.ncbi.nlm.nih.gov/pubmed/27259209
A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition. Hsiung CC, Bartman CR, Huang P, Ginart P, Stonestrom AJ, Keller CA, Face C, Jahn KS, Evans P, Sankaranarayanan L, Giardine B, Hardison RC, Raj A, Blobel GA Genes & development 27340175 Genes Dev 2016 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/27340175
Using variability in gene expression as a tool for studying gene regulation. Padovan-Merhar O, Raj A Wiley interdisciplinary reviews. Systems biology and medicine 23996796 Wiley Interdiscip Rev Syst Biol Med 2013 Nov-Dec https://www.ncbi.nlm.nih.gov/pubmed/23996796
Targeting tumor vasculature: expanding the potential of DNA cancer vaccines. Ugel S, Facciponte JG, De Sanctis F, Facciabene A Cancer immunology, immunotherapy : CII 26267042 Cancer Immunol Immunother 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26267042
Amendments: Author Correction: ClampFISH detects individual nucleic acid molecules using click chemistry-based amplification. Rouhanifard SH, Mellis IA, Dunagin M, Bayatpour S, Jiang CL, Dardani I, Symmons O, Emert B, Torre E, Cote A, Sullivan A, Stamatoyannopoulos JA, Raj A Nature biotechnology 30605160 Nat Biotechnol 2019 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/30605160
Spo0A~P imposes a temporal gate for the bimodal expression of competence in Bacillus subtilis. Mirouze N, Desai Y, Raj A, Dubnau D PLoS genetics 22412392 PLoS Genet 2012 https://www.ncbi.nlm.nih.gov/pubmed/22412392
The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA Molecular cell 28388437 Mol Cell 2017 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/28388437
Visualizing adenosine-to-inosine RNA editing in single mammalian cells. Mellis IA, Gupte R, Raj A, Rouhanifard SH Nature methods 28604724 Nat Methods 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28604724
Gene transcription is coordinated with, but not dependent on, cell divisions during C. elegans embryonic fate specification. Nair G, Walton T, Murray JI, Raj A Development (Cambridge, England) 23863485 Development 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23863485
Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation. Levesque MJ, Raj A Nature methods 23416756 Nat Methods 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23416756
Tumor endothelial marker 1-specific DNA vaccination targets tumor vasculature. Facciponte JG, Ugel S, De Sanctis F, Li C, Wang L, Nair G, Sehgal S, Raj A, Matthaiou E, Coukos G, Facciabene A The Journal of clinical investigation 24642465 J Clin Invest 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24642465
Visualization of lncRNA by single-molecule fluorescence in situ hybridization. Dunagin M, Cabili MN, Rinn J, Raj A Methods in molecular biology (Clifton, N.J.) 25555572 Methods Mol Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25555572
Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting. Symmons O, Chang M, Mellis IA, Kalish JM, Park J, Suszták K, Bartolomei MS, Raj A PLoS genetics 30625149 PLoS Genet 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30625149
Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms. Padovan-Merhar O, Nair GP, Biaesch AG, Mayer A, Scarfone S, Foley SW, Wu AR, Churchman LS, Singh A, Raj A Molecular cell 25866248 Mol Cell 2015 Apr 16 https://www.ncbi.nlm.nih.gov/pubmed/25866248
Enhancer Regulation of Transcriptional Bursting Parameters Revealed by Forced Chromatin Looping. Bartman CR, Hsu SC, Hsiung CC, Raj A, Blobel GA Molecular cell 27067601 Mol Cell 2016 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/27067601
Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency. Abranches E, Guedes AM, Moravec M, Maamar H, Svoboda P, Raj A, Henrique D Development (Cambridge, England) 25005472 Development 2014 Jul https://www.ncbi.nlm.nih.gov/pubmed/25005472
The Bicoid class homeodomain factors ceh-36/OTX and unc-30/PITX cooperate in C. elegans embryonic progenitor cells to regulate robust development. Walton T, Preston E, Nair G, Zacharias AL, Raj A, Murray JI PLoS genetics 25738873 PLoS Genet 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25738873
Dynamic enhancer-gene body contacts during transcription elongation. Lee K, Hsiung CC, Huang P, Raj A, Blobel GA Genes & development 26443845 Genes Dev 2015 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/26443845
LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint. Dimitrova N, Zamudio JR, Jong RM, Soukup D, Resnick R, Sarma K, Ward AJ, Raj A, Lee JT, Sharp PA, Jacks T Molecular cell 24857549 Mol Cell 2014 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/24857549
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance. Shaffer SM, Dunagin MC, Torborg SR, Torre EA, Emert B, Krepler C, Beqiri M, Sproesser K, Brafford PA, Xiao M, Eggan E, Anastopoulos IN, Vargas-Garcia CA, Singh A, Nathanson KL, Herlyn M, Raj A Nature 28607484 Nature 2017 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/28607484
Quantitative assessment of ratiometric bimolecular beacons as a tool for imaging single engineered RNA transcripts and measuring gene expression in living cells. Zhang X, Song Y, Shah AY, Lekova V, Raj A, Huang L, Behlke MA, Tsourkas A Nucleic acids research 23814183 Nucleic Acids Res 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23814183
Turbo FISH: a method for rapid single molecule RNA FISH. Shaffer SM, Wu MT, Levesque MJ, Raj A PloS one 24066168 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/24066168
linc-HOXA1 is a noncoding RNA that represses Hoxa1 transcription in cis. Maamar H, Cabili MN, Rinn J, Raj A Genes & development 23723417 Genes Dev 2013 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/23723417
The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. Kotzin JJ, Spencer SP, McCright SJ, Kumar DBU, Collet MA, Mowel WK, Elliott EN, Uyar A, Makiya MA, Dunagin MC, Harman CCD, Virtue AT, Zhu S, Bailis W, Stein J, Hughes C, Raj A, Wherry EJ, Goff LA, Klion AD, Rinn JL, Williams A, Flavell RA, Henao-Mejia J Nature 27525555 Nature 2016 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/27525555
SAVER: gene expression recovery for single-cell RNA sequencing. Huang M, Wang J, Torre E, Dueck H, Shaffer S, Bonasio R, Murray JI, Raj A, Li M, Zhang NR Nature methods 29941873 Nat Methods 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29941873
Nanoscale imaging of RNA with expansion microscopy. Chen F, Wassie AT, Cote AJ, Sinha A, Alon S, Asano S, Daugharthy ER, Chang JB, Marblestone A, Church GM, Raj A, Boyden ES Nature methods 27376770 Nat Methods 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27376770
Visualizing SNVs to quantify allele-specific expression in single cells. Levesque MJ, Ginart P, Wei Y, Raj A Nature methods 23913259 Nat Methods 2013 Sep https://www.ncbi.nlm.nih.gov/pubmed/23913259
Control of somatic tissue differentiation by the long non-coding RNA TINCR. Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, Aiyer S, Raj A, Rinn JL, Chang HY, Khavari PA Nature 23201690 Nature 2013 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/23201690
Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a. Weis B, Schmidt J, Maamar H, Raj A, Lin H, Tóth C, Riedmann K, Raddatz G, Seitz HK, Ho AD, Lyko F, Linhart HG Oncogene 24837369 Oncogene 2015 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/24837369
Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila. Panda D, Pascual-Garcia P, Dunagin M, Tudor M, Hopkins KC, Xu J, Gold B, Raj A, Capelson M, Cherry S Proceedings of the National Academy of Sciences of the United States of America 25197089 Proc Natl Acad Sci U S A 2014 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/25197089
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Paralkar VR, Mishra T, Luan J, Yao Y, Kossenkov AV, Anderson SM, Dunagin M, Pimkin M, Gore M, Sun D, Konuthula N, Raj A, An X, Mohandas N, Bodine DM, Hardison RC, Weiss MJ Blood 24497530 Blood 2014 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/24497530
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. Hacisuleyman E, Goff LA, Trapnell C, Williams A, Henao-Mejia J, Sun L, McClanahan P, Hendrickson DG, Sauvageau M, Kelley DR, Morse M, Engreitz J, Lander ES, Guttman M, Lodish HF, Flavell R, Raj A, Rinn JL Nature structural & molecular biology 24463464 Nat Struct Mol Biol 2014 Feb https://www.ncbi.nlm.nih.gov/pubmed/24463464
Single-cell differences in matrix gene expression do not predict matrix deposition. Cote AJ, McLeod CM, Farrell MJ, McClanahan PD, Dunagin MC, Raj A, Mauck RL Nature communications 26936319 Nat Commun 2016 Mar 3 https://www.ncbi.nlm.nih.gov/pubmed/26936319
Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH. Torre E, Dueck H, Shaffer S, Gospocic J, Gupte R, Bonasio R, Kim J, Murray J, Raj A Cell systems 29454938 Cell Syst 2018 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/29454938
Transcriptional Bursting Explains the Noise-Versus-Mean Relationship in mRNA and Protein Levels. Dar RD, Shaffer SM, Singh A, Razooky BS, Simpson ML, Raj A, Weinberger LS PloS one 27467384 PLoS One 2016 https://www.ncbi.nlm.nih.gov/pubmed/27467384
Heterogeneous lineage marker expression in naive embryonic stem cells is mostly due to spontaneous differentiation. Nair G, Abranches E, Guedes AM, Henrique D, Raj A Scientific reports 26292941 Sci Rep 2015 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/26292941
Multiplexed detection of viral infections using rapid in situ RNA analysis on a chip. Shaffer SM, Joshi RP, Chambers BS, Sterken D, Biaesch AG, Gabrieli DJ, Li Y, Feemster KA, Hensley SE, Issadore D, Raj A Lab on a chip 26113495 Lab Chip 2015 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/26113495
Robust hematopoietic progenitor cell commitment in the presence of a conflicting cue. Shah NA, Levesque MJ, Raj A, Sarkar CA Journal of cell science 26159733 J Cell Sci 2015 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/26159733
Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution. Cabili MN, Dunagin MC, McClanahan PD, Biaesch A, Padovan-Merhar O, Regev A, Rinn JL, Raj A Genome biology 25630241 Genome Biol 2015 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/25630241
Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I. Xu J, Mercado-López X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, López CB mBio 26443454 mBio 2015 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/26443454
Translating the genome in time and space: specialized ribosomes, RNA regulons, and RNA-binding proteins. Shi Z, Barna M Annual review of cell and developmental biology 26443190 Annu Rev Cell Dev Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26443190
RNA regulons in Hox 5' UTRs confer ribosome specificity to gene regulation. Xue S, Tian S, Fujii K, Kladwang W, Das R, Barna M Nature 25409156 Nature 2015 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/25409156
Differential Requirements for eIF4E Dose in Normal Development and Cancer. Truitt ML, Conn CS, Shi Z, Pang X, Tokuyasu T, Coady AM, Seo Y, Barna M, Ruggero D Cell 26095252 Cell 2015 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/26095252
Ribosomes take control. Barna M Proceedings of the National Academy of Sciences of the United States of America 23243144 Proc Natl Acad Sci U S A 2013 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/23243144
Cis-regulatory RNA elements that regulate specialized ribosome activity. Xue S, Barna M RNA biology 26327194 RNA Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26327194
Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide. Shi Z, Fujii K, Kovary KM, Genuth NR, Röst HL, Teruel MN, Barna M Molecular cell 28625553 Mol Cell 2017 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/28625553
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Tailor made protein synthesis for HSCs. Barna M, Ruggero D Cell stem cell 24702992 Cell Stem Cell 2014 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/24702992
The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M Cell 28575669 Cell 2017 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/28575669
Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Ishijima J, Shiroishi T, Barna M Cell 21529712 Cell 2011 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/21529712
Force Feedback Controls Motor Activity and Mechanical Properties of Self-Assembling Branched Actin Networks. Bieling P, Li TD, Weichsel J, McGorty R, Jreij P, Huang B, Fletcher DA, Mullins RD Cell 26771487 Cell 2016 Jan 14 https://www.ncbi.nlm.nih.gov/pubmed/26771487
Single cell optical imaging and spectroscopy. Stender AS, Marchuk K, Liu C, Sander S, Meyer MW, Smith EA, Neupane B, Wang G, Li J, Cheng JX, Huang B, Fang N Chemical reviews 23410134 Chem Rev 2013 Apr 10 https://www.ncbi.nlm.nih.gov/pubmed/23410134
Versatile protein tagging in cells with split fluorescent protein. Kamiyama D, Sekine S, Barsi-Rhyne B, Hu J, Chen B, Gilbert LA, Ishikawa H, Leonetti MD, Marshall WF, Weissman JS, Huang B Nature communications 26988139 Nat Commun 2016 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/26988139
Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization. Mennella V, Keszthelyi B, McDonald KL, Chhun B, Kan F, Rogers GC, Huang B, Agard DA Nature cell biology 23086239 Nat Cell Biol 2012 Nov https://www.ncbi.nlm.nih.gov/pubmed/23086239
2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas. Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM Cancer research 29358170 Cancer Res 2018 May 1 https://www.ncbi.nlm.nih.gov/pubmed/29358170
Correction of depth-dependent aberrations in 3D single-molecule localization and super-resolution microscopy. McGorty R, Schnitzbauer J, Zhang W, Huang B Optics letters 24562125 Opt Lett 2014 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/24562125
Active Microscope Stabilization in Three Dimensions Using Image Correlation. McGorty R, Kamiyama D, Huang B Optical nanoscopy 24380058 Opt Nanoscopy 2013 Apr 18 https://www.ncbi.nlm.nih.gov/pubmed/24380058
Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory. Puchner EM, Walter JM, Kasper R, Huang B, Lim WA Proceedings of the National Academy of Sciences of the United States of America 24043832 Proc Natl Acad Sci U S A 2013 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/24043832
Localization events-based sample drift correction for localization microscopy with redundant cross-correlation algorithm. Wang Y, Schnitzbauer J, Hu Z, Li X, Cheng Y, Huang ZL, Huang B Optics express 24977854 Opt Express 2014 Jun 30 https://www.ncbi.nlm.nih.gov/pubmed/24977854
Deformed alignment of super-resolution images for semi-flexible structures. Shi X, Garcia G 3rd, Wang Y, Reiter JF, Huang B PloS one 30865666 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/30865666
Improved split fluorescent proteins for endogenous protein labeling. Feng S, Sekine S, Pessino V, Li H, Leonetti MD, Huang B Nature communications 28851864 Nat Commun 2017 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/28851864
Covalent Protein Labeling by SpyTag-SpyCatcher in Fixed Cells for Super-Resolution Microscopy. Pessino V, Citron YR, Feng S, Huang B Chembiochem : a European journal of chemical biology 28514494 Chembiochem 2017 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/28514494
Amorphous no more: subdiffraction view of the pericentriolar material architecture. Mennella V, Agard DA, Huang B, Pelletier L Trends in cell biology 24268653 Trends Cell Biol 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24268653
A scalable strategy for high-throughput GFP tagging of endogenous human proteins. Leonetti MD, Sekine S, Kamiyama D, Weissman JS, Huang B Proceedings of the National Academy of Sciences of the United States of America 27274053 Proc Natl Acad Sci U S A 2016 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/27274053
Imaging Specific Genomic DNA in Living Cells. Chen B, Guan J, Huang B Annual review of biophysics 27145877 Annu Rev Biophys 2016 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/27145877
Live Cell Imaging of Endogenous mRNA Using RNA-Based Fluorescence "Turn-On" Probe. Ong WQ, Citron YR, Sekine S, Huang B ACS chemical biology 28103687 ACS Chem Biol 2017 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/28103687
Correlation analysis framework for localization-based superresolution microscopy. Schnitzbauer J, Wang Y, Zhao S, Bakalar M, Nuwal T, Chen B, Huang B Proceedings of the National Academy of Sciences of the United States of America 29531072 Proc Natl Acad Sci U S A 2018 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/29531072
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4Pi fluorescence detection and 3D particle localization with a single objective. Schnitzbauer J, McGorty R, Huang B Optics express 24105517 Opt Express 2013 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/24105517
SnapShot: Light microscopy. Kasper R, Huang B Cell 22118471 Cell 2011 Nov 23 https://www.ncbi.nlm.nih.gov/pubmed/22118471
The centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles. Citron YR, Fagerstrom CJ, Keszthelyi B, Huang B, Rusan NM, Kelly MJS, Agard DA PloS one 29315319 PLoS One 2018 https://www.ncbi.nlm.nih.gov/pubmed/29315319
Super-resolution microscopy reveals that disruption of ciliary transition-zone architecture causes Joubert syndrome. Shi X, Garcia G 3rd, Van De Weghe JC, McGorty R, Pazour GJ, Doherty D, Huang B, Reiter JF Nature cell biology 28846093 Nat Cell Biol 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28846093
EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms. van Lengerich B, Agnew C, Puchner EM, Huang B, Jura N Proceedings of the National Academy of Sciences of the United States of America 28320942 Proc Natl Acad Sci U S A 2017 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/28320942
Heavy water: a simple solution to increasing the brightness of fluorescent proteins in super-resolution imaging. Ong WQ, Citron YR, Schnitzbauer J, Kamiyama D, Huang B Chemical communications (Cambridge, England) 26226621 Chem Commun (Camb) 2015 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/26226621
Label-retention expansion microscopy. Shi X, Li Q, Dai Z, Tran AA, Feng S, Ramirez AD, Lin Z, Wang X, Chow TT, Chen J, Kumar D, McColloch AR, Reiter JF, Huang EJ, Seiple IB, Huang B The Journal of cell biology 34228783 J Cell Biol 2021 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/34228783
Cross-hierarchy systems principles. Goentoro L Current opinion in systems biology 28983520 Curr Opin Syst Biol 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/28983520
Signaling pathways as linear transmitters. Nunns H, Goentoro L eLife 30222104 Elife 2018 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/30222104
The functional role of astrocyte calcium signaling in cortical blood flow regulation. Biesecker KR, Srienc AI The Journal of neuroscience : the official journal of the Society for Neuroscience 25609605 J Neurosci 2015 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/25609605
Sensing relative signal in the Tgf-β/Smad pathway. Frick CL, Yarka C, Nunns H, Goentoro L Proceedings of the National Academy of Sciences of the United States of America 28320972 Proc Natl Acad Sci U S A 2017 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/28320972
Two-Element Transcriptional Regulation in the Canonical Wnt Pathway. Kim K, Cho J, Hilzinger TS, Nunns H, Liu A, Ryba BE, Goentoro L Current biology : CB 28756947 Curr Biol 2017 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/28756947
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Identification of the minimal cytolytic unit for streptolysin S and an expansion of the toxin family. Molloy EM, Casjens SR, Cox CL, Maxson T, Ethridge NA, Margos G, Fingerle V, Mitchell DA BMC microbiology 26204951 BMC Microbiol 2015 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/26204951
Targeting Reactive Carbonyls for Identifying Natural Products and Their Biosynthetic Origins. Maxson T, Tietz JI, Hudson GA, Guo XR, Tai HC, Mitchell DA Journal of the American Chemical Society 27797509 J Am Chem Soc 2016 Nov 23 https://www.ncbi.nlm.nih.gov/pubmed/27797509
HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis. Zhang Y, Fu-Yang Lin, Li K, Zhu W, Liu YL, Cao R, Pang R, Lee E, Axelson J, Hensler M, Wang K, Molohon KJ, Wang Y, Mitchell DA, Nizet V, Oldfield E ACS medicinal chemistry letters 22662288 ACS Med Chem Lett 2012 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/22662288
Engineering unnatural variants of plantazolicin through codon reprogramming. Deane CD, Melby JO, Molohon KJ, Susarrey AR, Mitchell DA ACS chemical biology 23823732 ACS Chem Biol 2013 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/23823732
Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. Hao Y, Saint-Vincent PMB, Sharma A, Mitchell DA, Nair SK ACS chemical biology 25635336 ACS Chem Biol 2015 May 15 https://www.ncbi.nlm.nih.gov/pubmed/25635336
Undecaprenyl diphosphate synthase inhibitors: antibacterial drug leads. Sinko W, Wang Y, Zhu W, Zhang Y, Feixas F, Cox CL, Mitchell DA, Oldfield E, McCammon JA Journal of medicinal chemistry 24827744 J Med Chem 2014 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/24827744
Nucleophilic 1,4-additions for natural product discovery. Cox CL, Tietz JI, Sokolowski K, Melby JO, Doroghazi JR, Mitchell DA ACS chemical biology 24937678 ACS Chem Biol 2014 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/24937678
Selectivity, directionality, and promiscuity in peptide processing from a Bacillus sp. Al Hakam cyclodehydratase. Melby JO, Dunbar KL, Trinh NQ, Mitchell DA Journal of the American Chemical Society 22401305 J Am Chem Soc 2012 Mar 21 https://www.ncbi.nlm.nih.gov/pubmed/22401305
Multitarget drug discovery for tuberculosis and other infectious diseases. Li K, Schurig-Briccio LA, Feng X, Upadhyay A, Pujari V, Lechartier B, Fontes FL, Yang H, Rao G, Zhu W, Gulati A, No JH, Cintra G, Bogue S, Liu YL, Molohon K, Orlean P, Mitchell DA, Freitas-Junior L, Ren F, Sun H, Jiang T, Li Y, Guo RT, Cole ST, Gennis RB, Crick DC, Oldfield E Journal of medicinal chemistry 24568559 J Med Chem 2014 Apr 10 https://www.ncbi.nlm.nih.gov/pubmed/24568559
Head-to-Head Prenyl Synthases in Pathogenic Bacteria. Schwalen CJ, Feng X, Liu W, O-Dowd B, Ko TP, Shin CJ, Guo RT, Mitchell DA, Oldfield E Chembiochem : a European journal of chemical biology 28340291 Chembiochem 2017 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/28340291
Synthesis of plantazolicin analogues enables dissection of ligand binding interactions of a highly selective methyltransferase. Sharma A, Saint-Vincent PMB, Mitchell DA Organic letters 24063702 Org Lett 2013 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/24063702
Targeted Treatment for Bacterial Infections: Prospects for Pathogen-Specific Antibiotics Coupled with Rapid Diagnostics. Maxson T, Mitchell DA Tetrahedron 27429480 Tetrahedron 2016 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/27429480
Crystal structure and absolute configuration of (3S,4aS,8aS)-N-tert-butyl-2-[(S)-3-(2-chloro-4-nitro-benzamido)-2-hy-droxy-prop-yl]deca-hydro-isoquinoline-3-carboxamide and (3S,4aS,8aS)-N-tert-butyl-2-{(S)-2-[(S)-1-(2-chloro-4-nitro-benzoyl)pyrrolidin-2-yl]-2-hy-droxy-eth-yl}deca-hydro-iso-quinoline-3-carboxamide. Maxson T, Bertke JA, Gray DL, Mitchell DA Acta crystallographica. Section E, Crystallographic communications 26594520 Acta Crystallogr E Crystallogr Commun 2015 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/26594520
The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles. Cox CL, Doroghazi JR, Mitchell DA BMC genomics 26462797 BMC Genomics 2015 Oct 13 https://www.ncbi.nlm.nih.gov/pubmed/26462797
In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin. Hudson GA, Zhang Z, Tietz JI, Mitchell DA, van der Donk WA Journal of the American Chemical Society 26675417 J Am Chem Soc 2015 Dec 30 https://www.ncbi.nlm.nih.gov/pubmed/26675417
Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis. Njire M, Wang N, Wang B, Tan Y, Cai X, Liu Y, Mugweru J, Guo J, Hameed HMA, Tan S, Liu J, Yew WW, Nuermberger E, Lamichhane G, Liu J, Zhang T Antimicrobial agents and chemotherapy 28438933 Antimicrob Agents Chemother 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28438933
Carbapenems against Mycobacterium tuberculosis: a review of the evidence. Jaganath D, Lamichhane G, Shah M The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 27776583 Int J Tuberc Lung Dis 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27776583
Non-classical transpeptidases yield insight into new antibacterials. Kumar P, Kaushik A, Lloyd EP, Li SG, Mattoo R, Ammerman NC, Bell DT, Perryman AL, Zandi TA, Ekins S, Ginell SL, Townsend CA, Freundlich JS, Lamichhane G Nature chemical biology 27820797 Nat Chem Biol 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27820797
Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactams. Schoonmaker MK, Bishai WR, Lamichhane G Journal of bacteriology 24464457 J Bacteriol 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24464457
REMap: Operon map of M. tuberculosis based on RNA sequence data. Pelly S, Winglee K, Xia FF, Stevens RL, Bishai WR, Lamichhane G Tuberculosis (Edinburgh, Scotland) 27450008 Tuberculosis (Edinb) 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27450008
Ldt(Mav2), a nonclassical transpeptidase and susceptibility of Mycobacterium avium to carbapenems. Mattoo R, Lloyd EP, Kaushik A, Kumar P, Brunelle JL, Townsend CA, Lamichhane G Future microbiology 28555497 Future Microbiol 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28555497
Targeting the cell wall of Mycobacterium tuberculosis: a molecular modeling investigation of the interaction of imipenem and meropenem with L,D-transpeptidase 2. Silva JR, Bishai WR, Govender T, Lamichhane G, Maguire GE, Kruger HG, Lameira J, Alves CN Journal of biomolecular structure & dynamics 25762064 J Biomol Struct Dyn 2016 https://www.ncbi.nlm.nih.gov/pubmed/25762064
Intrabacterial Metabolism Obscures the Successful Prediction of an InhA Inhibitor of Mycobacterium tuberculosis. Wang X, Perryman AL, Li SG, Paget SD, Stratton TP, Lemenze A, Olson AJ, Ekins S, Kumar P, Freundlich JS ACS infectious diseases 31625383 ACS Infect Dis 2019 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/31625383
Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development. Moraes GL, Gomes GC, Monteiro de Sousa PR, Alves CN, Govender T, Kruger HG, Maguire GE, Lamichhane G, Lameira J Tuberculosis (Edinburgh, Scotland) 25701501 Tuberculosis (Edinb) 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25701501
Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis. Brammer Basta LA, Ghosh A, Pan Y, Jakoncic J, Lloyd EP, Townsend CA, Lamichhane G, Bianchet MA The Journal of biological chemistry 26304120 J Biol Chem 2015 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/26304120
Carbapenems and Rifampin Exhibit Synergy against Mycobacterium tuberculosis and Mycobacterium abscessus. Kaushik A, Makkar N, Pandey P, Parrish N, Singh U, Lamichhane G Antimicrobial agents and chemotherapy 26259792 Antimicrob Agents Chemother 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26259792
Targeting the cell wall of Mycobacterium tuberculosis: structure and mechanism of L,D-transpeptidase 2. Erdemli SB, Gupta R, Bishai WR, Lamichhane G, Amzel LM, Bianchet MA Structure (London, England : 1993) 23103390 Structure 2012 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/23103390
Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt(Mt2) by biapenem and tebipenem. Bianchet MA, Pan YH, Basta LAB, Saavedra H, Lloyd EP, Kumar P, Mattoo R, Townsend CA, Lamichhane G BMC biochemistry 28545389 BMC Biochem 2017 May 25 https://www.ncbi.nlm.nih.gov/pubmed/28545389
An evolved oxazolidinone with selective potency against Mycobacterium tuberculosis and gram positive bacteria. Kaushik A, Heuer AM, Bell DT, Culhane JC, Ebner DC, Parrish N, Ippoliti JT, Lamichhane G Bioorganic & medicinal chemistry letters 27329794 Bioorg Med Chem Lett 2016 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/27329794
A screen for non-coding RNA in Mycobacterium tuberculosis reveals a cAMP-responsive RNA that is expressed during infection. Pelly S, Bishai WR, Lamichhane G Gene 22446041 Gene 2012 May 25 https://www.ncbi.nlm.nih.gov/pubmed/22446041
Mutation in an Unannotated Protein Confers Carbapenem Resistance in Mycobacterium tuberculosis. Kumar P, Kaushik A, Bell DT, Chauhan V, Xia F, Stevens RL, Lamichhane G Antimicrobial agents and chemotherapy 28069655 Antimicrob Agents Chemother 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28069655
In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis. Kaushik A, Ammerman NC, Tasneen R, Story-Roller E, Dooley KE, Dorman SE, Nuermberger EL, Lamichhane G The Journal of antimicrobial chemotherapy 28575382 J Antimicrob Chemother 2017 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/28575382
Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins. Kumar P, Chauhan V, Silva JRA, Lameira J, d'Andrea FB, Li SG, Ginell SL, Freundlich JS, Alves CN, Bailey S, Cohen KA, Lamichhane G Antimicrobial agents and chemotherapy 28760902 Antimicrob Agents Chemother 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28760902
A virtual screen discovers novel, fragment-sized inhibitors of Mycobacterium tuberculosis InhA. Perryman AL, Yu W, Wang X, Ekins S, Forli S, Li SG, Freundlich JS, Tonge PJ, Olson AJ Journal of chemical information and modeling 25636146 J Chem Inf Model 2015 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/25636146
Role of the Cys154Arg Substitution in Ribosomal Protein L3 in Oxazolidinone Resistance in Mycobacterium tuberculosis. Makafe GG, Cao Y, Tan Y, Julius M, Liu Z, Wang C, Njire MM, Cai X, Liu T, Wang B, Pang W, Tan S, Zhang B, Yew WW, Lamichhane G, Guo J, Zhang T Antimicrobial agents and chemotherapy 26953211 Antimicrob Agents Chemother 2016 May https://www.ncbi.nlm.nih.gov/pubmed/26953211
Pooled ChIP-Seq Links Variation in Transcription Factor Binding to Complex Disease Risk. Tehranchi AK, Myrthil M, Martin T, Hie BL, Golan D, Fraser HB Cell 27087447 Cell 2016 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/27087447
Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment. Braas D, Ahler E, Tam B, Nathanson D, Riedinger M, Benz MR, Smith KB, Eilber FC, Witte ON, Tap WD, Wu H, Christofk HR Cancer discovery 23230188 Cancer Discov 2012 Dec https://www.ncbi.nlm.nih.gov/pubmed/23230188
MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PAL, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, Dubinett SM, Critchlow SE, Kurdistani SK, Goodglick L, Braas D, Graeber TG, Christofk HR Cell reports 26876179 Cell Rep 2016 Feb 23 https://www.ncbi.nlm.nih.gov/pubmed/26876179
MYC-induced reprogramming of glutamine catabolism supports optimal virus replication. Thai M, Thaker SK, Feng J, Du Y, Hu H, Ting Wu T, Graeber TG, Braas D, Christofk HR Nature communications 26561297 Nat Commun 2015 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/26561297
Doxycycline alters metabolism and proliferation of human cell lines. Ahler E, Sullivan WJ, Cass A, Braas D, York AG, Bensinger SJ, Graeber TG, Christofk HR PloS one 23741339 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23741339
Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication. Thai M, Graham NA, Braas D, Nehil M, Komisopoulou E, Kurdistani SK, McCormick F, Graeber TG, Christofk HR Cell metabolism 24703700 Cell Metab 2014 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/24703700
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. Krall AS, Xu S, Graeber TG, Braas D, Christofk HR Nature communications 27126896 Nat Commun 2016 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/27126896
The ecological basis of morphogenesis: branching patterns in swarming colonies of bacteria. Deng P, de Vargas Roditi L, van Ditmarsch D, Xavier JB New journal of physics 24587694 New J Phys 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/24587694
Tumour-stromal interactions generate emergent persistence in collective cancer cell migration. Chang WK, Carmona-Fontaine C, Xavier JB Interface focus 24511381 Interface Focus 2013 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/24511381
Cell-Size Homeostasis and the Incremental Rule in a Bacterial Pathogen. Deforet M, van Ditmarsch D, Xavier JB Biophysical journal 26244734 Biophys J 2015 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/26244734
Integration of Metabolic and Quorum Sensing Signals Governing the Decision to Cooperate in a Bacterial Social Trait. Boyle KE, Monaco H, van Ditmarsch D, Deforet M, Xavier JB PLoS computational biology 26102206 PLoS Comput Biol 2015 May https://www.ncbi.nlm.nih.gov/pubmed/26102206
Towards predictive models of the human gut microbiome. Bucci V, Xavier JB Journal of molecular biology 24727124 J Mol Biol 2014 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/24727124
Social interaction, noise and antibiotic-mediated switches in the intestinal microbiota. Bucci V, Bradde S, Biroli G, Xavier JB PLoS computational biology 22577356 PLoS Comput Biol 2012 https://www.ncbi.nlm.nih.gov/pubmed/22577356
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile. Buffie CG, Bucci V, Stein RR, McKenney PT, Ling L, Gobourne A, No D, Liu H, Kinnebrew M, Viale A, Littmann E, van den Brink MR, Jenq RR, Taur Y, Sander C, Cross JR, Toussaint NC, Xavier JB, Pamer EG Nature 25337874 Nature 2015 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/25337874
Cutting through the complexity of cell collectives. Nadell CD, Bucci V, Drescher K, Levin SA, Bassler BL, Xavier JB Proceedings. Biological sciences 23363630 Proc Biol Sci 2013 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/23363630
Turning ecology and evolution against cancer. Korolev KS, Xavier JB, Gore J Nature reviews. Cancer 24739582 Nat Rev Cancer 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24739582
Multilevel selection analysis of a microbial social trait. de Vargas Roditi L, Boyle KE, Xavier JB Molecular systems biology 23959025 Mol Syst Biol 2013 Aug 20 https://www.ncbi.nlm.nih.gov/pubmed/23959025
Emergence of spatial structure in the tumor microenvironment due to the Warburg effect. Carmona-Fontaine C, Bucci V, Akkari L, Deforet M, Joyce JA, Xavier JB Proceedings of the National Academy of Sciences of the United States of America 24218566 Proc Natl Acad Sci U S A 2013 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/24218566
Sociomicrobiology and Pathogenic Bacteria. Xavier JB Microbiology spectrum 27337482 Microbiol Spectr 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27337482
Convergent evolution of hyperswarming leads to impaired biofilm formation in pathogenic bacteria. van Ditmarsch D, Boyle KE, Sakhtah H, Oyler JE, Nadell CD, Déziel É, Dietrich LE, Xavier JB Cell reports 23954787 Cell Rep 2013 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/23954787
Exploiting social evolution in biofilms. Boyle KE, Heilmann S, van Ditmarsch D, Xavier JB Current opinion in microbiology 23357558 Curr Opin Microbiol 2013 Apr https://www.ncbi.nlm.nih.gov/pubmed/23357558
Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation. Taur Y, Xavier JB, Lipuma L, Ubeda C, Goldberg J, Gobourne A, Lee YJ, Dubin KA, Socci ND, Viale A, Perales MA, Jenq RR, van den Brink MR, Pamer EG Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 22718773 Clin Infect Dis 2012 Oct https://www.ncbi.nlm.nih.gov/pubmed/22718773
Hyperswarming adaptations in a bacterium improve collective motility without enhancing single cell motility. Deforet M, van Ditmarsch D, Carmona-Fontaine C, Xavier JB Soft matter 24622509 Soft Matter 2014 Apr 14 https://www.ncbi.nlm.nih.gov/pubmed/24622509
Ecological modeling from time-series inference: insight into dynamics and stability of intestinal microbiota. Stein RR, Bucci V, Toussaint NC, Buffie CG, Rätsch G, Pamer EG, Sander C, Xavier JB PLoS computational biology 24348232 PLoS Comput Biol 2013 https://www.ncbi.nlm.nih.gov/pubmed/24348232
Metabolism and the Evolution of Social Behavior. Boyle KE, Monaco HT, Deforet M, Yan J, Wang Z, Rhee K, Xavier JB Molecular biology and evolution 28595344 Mol Biol Evol 2017 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/28595344
Facultative control of matrix production optimizes competitive fitness in Pseudomonas aeruginosa PA14 biofilm models. Madsen JS, Lin YC, Squyres GR, Price-Whelan A, de Santiago Torio A, Song A, Cornell WC, Sørensen SJ, Xavier JB, Dietrich LE Applied and environmental microbiology 26431965 Appl Environ Microbiol 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26431965
Human symbionts inject and neutralize antibacterial toxins to persist in the gut. Wexler AG, Bao Y, Whitney JC, Bobay LM, Xavier JB, Schofield WB, Barry NA, Russell AB, Tran BQ, Goo YA, Goodlett DR, Ochman H, Mougous JD, Goodman AL Proceedings of the National Academy of Sciences of the United States of America 26957597 Proc Natl Acad Sci U S A 2016 Mar 29 https://www.ncbi.nlm.nih.gov/pubmed/26957597
Corynebacterium glutamicum Metabolic Engineering with CRISPR Interference (CRISPRi). Cleto S, Jensen JV, Wendisch VF, Lu TK ACS synthetic biology 26829286 ACS Synth Biol 2016 May 20 https://www.ncbi.nlm.nih.gov/pubmed/26829286
Synthetic biology. Genomically encoded analog memory with precise in vivo DNA writing in living cell populations. Farzadfard F, Lu TK Science (New York, N.Y.) 25395541 Science 2014 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/25395541
Synthetic analog and digital circuits for cellular computation and memory. Purcell O, Lu TK Current opinion in biotechnology 24794536 Curr Opin Biotechnol 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/24794536
Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Nissim L, Perli SD, Fridkin A, Perez-Pinera P, Lu TK Molecular cell 24837679 Mol Cell 2014 May 22 https://www.ncbi.nlm.nih.gov/pubmed/24837679
Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas. Farzadfard F, Perli SD, Lu TK ACS synthetic biology 23977949 ACS Synth Biol 2013 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/23977949
Synthetic biology of antimicrobial discovery. Zakeri B, Lu TK ACS synthetic biology 23654251 ACS Synth Biol 2013 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/23654251
Synthetic mixed-signal computation in living cells. Rubens JR, Selvaggio G, Lu TK Nature communications 27255669 Nat Commun 2016 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/27255669
Single-molecule detection of protein efflux from microorganisms using fluorescent single-walled carbon nanotube sensor arrays. Landry MP, Ando H, Chen AY, Cao J, Kottadiel VI, Chio L, Yang D, Dong J, Lu TK, Strano MS Nature nanotechnology 28114298 Nat Nanotechnol 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28114298
Hydrogel-based biocontainment of bacteria for continuous sensing and computation. Tang TC, Tham E, Liu X, Yehl K, Rovner AJ, Yuk H, de la Fuente-Nunez C, Isaacs FJ, Zhao X, Lu TK Nature chemical biology 33820990 Nat Chem Biol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33820990
Natural combinatorial genetics and prolific polyamine production enable siderophore diversification in Serratia plymuthica. Cleto S, Haslinger K, Prather KLJ, Lu TK BMC biology 33722216 BMC Biol 2021 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/33722216
Surface charge-switching polymeric nanoparticles for bacterial cell wall-targeted delivery of antibiotics. Radovic-Moreno AF, Lu TK, Puscasu VA, Yoon CJ, Langer R, Farokhzad OC ACS nano 22471841 ACS Nano 2012 May 22 https://www.ncbi.nlm.nih.gov/pubmed/22471841
Engineering living functional materials. Chen AY, Zhong C, Lu TK ACS synthetic biology 25592034 ACS Synth Biol 2015 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/25592034
Synthetic recombinase-based state machines in living cells. Roquet N, Soleimany AP, Ferris AC, Aaronson S, Lu TK Science (New York, N.Y.) 27463678 Science 2016 Jul 22 https://www.ncbi.nlm.nih.gov/pubmed/27463678
A Modular Toolkit for Generating Pichia pastoris Secretion Libraries. Obst U, Lu TK, Sieber V ACS synthetic biology 28252957 ACS Synth Biol 2017 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/28252957
Advancing bacteriophage-based microbial diagnostics with synthetic biology. Lu TK, Bowers J, Koeris MS Trends in biotechnology 23608522 Trends Biotechnol 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23608522
Strong underwater adhesives made by self-assembling multi-protein nanofibres. Zhong C, Gurry T, Cheng AA, Downey J, Deng Z, Stultz CM, Lu TK Nature nanotechnology 25240674 Nat Nanotechnol 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25240674
Rule-based design of synthetic transcription factors in eukaryotes. Purcell O, Peccoud J, Lu TK ACS synthetic biology 24933274 ACS Synth Biol 2014 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/24933274
Synthetic biology: an emerging engineering discipline. Cheng AA, Lu TK Annual review of biomedical engineering 22577777 Annu Rev Biomed Eng 2012 https://www.ncbi.nlm.nih.gov/pubmed/22577777
Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing. Ando H, Lemire S, Pires DP, Lu TK Cell systems 26973885 Cell Syst 2015 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/26973885
Foundations and Emerging Paradigms for Computing in Living Cells. Ma KC, Perli SD, Lu TK Journal of molecular biology 26908220 J Mol Biol 2016 Feb 27 https://www.ncbi.nlm.nih.gov/pubmed/26908220
Engineering genetic circuits that compute and remember. Siuti P, Yazbek J, Lu TK Nature protocols 24810038 Nat Protoc 2014 https://www.ncbi.nlm.nih.gov/pubmed/24810038
Digital and analog gene circuits for biotechnology. Roquet N, Lu TK Biotechnology journal 24677719 Biotechnol J 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24677719
Massively parallel high-order combinatorial genetics in human cells. Wong AS, Choi GC, Cheng AA, Purcell O, Lu TK Nature biotechnology 26280411 Nat Biotechnol 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26280411
DNA nanotechnology: new adventures for an old warhorse. Zakeri B, Lu TK Current opinion in chemical biology 26056949 Curr Opin Chem Biol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26056949
A synthetic biology framework for programming eukaryotic transcription functions. Khalil AS, Lu TK, Bashor CJ, Ramirez CL, Pyenson NC, Joung JK, Collins JJ Cell 22863014 Cell 2012 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/22863014
Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis. Yehl K, Lemire S, Yang AC, Ando H, Mimee M, Torres MT, de la Fuente-Nunez C, Lu TK Cell 31585083 Cell 2019 Oct 3 https://www.ncbi.nlm.nih.gov/pubmed/31585083
Towards a whole-cell modeling approach for synthetic biology. Purcell O, Jain B, Karr JR, Covert MW, Lu TK Chaos (Woodbury, N.Y.) 23822510 Chaos 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23822510
Enhancing phage therapy through synthetic biology and genome engineering. Lenneman BR, Fernbach J, Loessner MJ, Lu TK, Kilcher S Current opinion in biotechnology 33310655 Curr Opin Biotechnol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33310655
Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM. Wong AS, Choi GC, Cui CH, Pregernig G, Milani P, Adam M, Perli SD, Kazer SW, Gaillard A, Hermann M, Shalek AK, Fraenkel E, Lu TK Proceedings of the National Academy of Sciences of the United States of America 26864203 Proc Natl Acad Sci U S A 2016 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/26864203
Programming a Human Commensal Bacterium, Bacteroides thetaiotaomicron, to Sense and Respond to Stimuli in the Murine Gut Microbiota. Mimee M, Tucker AC, Voigt CA, Lu TK Cell systems 26918244 Cell Syst 2015 Jul 29 https://www.ncbi.nlm.nih.gov/pubmed/26918244
Gene networks that compensate for crosstalk with crosstalk. Müller IE, Rubens JR, Jun T, Graham D, Xavier R, Lu TK Nature communications 31492904 Nat Commun 2019 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/31492904
Synthesis and patterning of tunable multiscale materials with engineered cells. Chen AY, Deng Z, Billings AN, Seker UO, Lu MY, Citorik RJ, Zakeri B, Lu TK Nature materials 24658114 Nat Mater 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24658114
Enhanced killing of antibiotic-resistant bacteria enabled by massively parallel combinatorial genetics. Cheng AA, Ding H, Lu TK Proceedings of the National Academy of Sciences of the United States of America 25114216 Proc Natl Acad Sci U S A 2014 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/25114216
Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases. Citorik RJ, Mimee M, Lu TK Nature biotechnology 25240928 Nat Biotechnol 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25240928
Bacteriophage-based synthetic biology for the study of infectious diseases. Citorik RJ, Mimee M, Lu TK Current opinion in microbiology 24997401 Curr Opin Microbiol 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24997401
Synthetic Biogenesis of Bacterial Amyloid Nanomaterials with Tunable Inorganic-Organic Interfaces and Electrical Conductivity. Seker UO, Chen AY, Citorik RJ, Lu TK ACS synthetic biology 27794590 ACS Synth Biol 2017 Feb 17 https://www.ncbi.nlm.nih.gov/pubmed/27794590
Multiplexed Sequence Encoding: A Framework for DNA Communication. Zakeri B, Carr PA, Lu TK PloS one 27050646 PLoS One 2016 https://www.ncbi.nlm.nih.gov/pubmed/27050646
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Full-colour Jabuticaba-like nanostructures via the multiplex and orthogonal self-assembly of protein-conjugated quantum dots with engineered biofilms. Deng Z, Chen AY, Zakeri B, Zhong C, Lu TK Materials horizons 36786820 Mater Horiz 2023 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/36786820
TeloPCR-seq: a high-throughput sequencing approach for telomeres. Bennett HW, Liu N, Hu Y, King MC FEBS letters 27714790 FEBS Lett 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27714790
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Forces, fluctuations, and self-organization in the nucleus. Pederson T, King MC, Marko JF Molecular biology of the cell 26543199 Mol Biol Cell 2015 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/26543199
The KASH protein Kms2 coordinates mitotic remodeling of the spindle pole body. Wälde S, King MC Journal of cell science 24963130 J Cell Sci 2014 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/24963130
Improved Determination of Subnuclear Position Enabled by Three-Dimensional Membrane Reconstruction. Zhao Y, Schreiner SM, Koo PK, Colombi P, King MC, Mochrie SG Biophysical journal 27410730 Biophys J 2016 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/27410730
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Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates. Tillo SE, Xiong WH, Takahashi M, Miao S, Andrade AL, Fortin DA, Yang G, Qin M, Smoody BF, Stork PJS, Zhong H Cell reports 28423323 Cell Rep 2017 Apr 18 https://www.ncbi.nlm.nih.gov/pubmed/28423323
Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins. Fortin DA, Tillo SE, Yang G, Rah JC, Melander JB, Bai S, Soler-Cedeño O, Qin M, Zemelman BV, Guo C, Mao T, Zhong H The Journal of neuroscience : the official journal of the Society for Neuroscience 25505322 J Neurosci 2014 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/25505322
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A comprehensive excitatory input map of the striatum reveals novel functional organization. Hunnicutt BJ, Jongbloets BC, Birdsong WT, Gertz KJ, Zhong H, Mao T eLife 27892854 Elife 2016 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/27892854
Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality. Rangaraju S, Solis GM, Thompson RC, Gomez-Amaro RL, Kurian L, Encalada SE, Niculescu AB 3rd, Salomon DR, Petrascheck M eLife 26623667 Elife 2015 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/26623667
The aging transcriptome: read between the lines. Perez-Gomez A, Buxbaum JN, Petrascheck M Current opinion in neurobiology 32563038 Curr Opin Neurobiol 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32563038
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The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J Nature 24828042 Nature 2014 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/24828042
Mood, stress and longevity: convergence on ANK3. Rangaraju S, Levey DF, Nho K, Jain N, Andrews KD, Le-Niculescu H, Salomon DR, Saykin AJ, Petrascheck M, Niculescu AB Molecular psychiatry 27217151 Mol Psychiatry 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27217151
Atypical antidepressants extend lifespan of Caenorhabditis elegans by activation of a non-cell-autonomous stress response. Rangaraju S, Solis GM, Andersson SI, Gomez-Amaro RL, Kardakaris R, Broaddus CD, Niculescu AB 3rd, Petrascheck M Aging cell 26255886 Aging Cell 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26255886
Measuring Food Intake and Nutrient Absorption in Caenorhabditis elegans. Gomez-Amaro RL, Valentine ER, Carretero M, LeBoeuf SE, Rangaraju S, Broaddus CD, Solis GM, Williamson JR, Petrascheck M Genetics 25903497 Genetics 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25903497
Measuring Caenorhabditis elegans life span in 96 well microtiter plates. Solis GM, Petrascheck M Journal of visualized experiments : JoVE 21445049 J Vis Exp 2011 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/21445049
A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia. Perez-Gomez A, Carretero M, Weber N, Peterka V, To A, Titova V, Solis G, Osborn O, Petrascheck M Nature communications 30532051 Nat Commun 2018 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/30532051
Computational Analysis of Lifespan Experiment Reproducibility. Petrascheck M, Miller DL Frontiers in genetics 28713422 Front Genet 2017 https://www.ncbi.nlm.nih.gov/pubmed/28713422
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A pharmacological network for lifespan extension in Caenorhabditis elegans. Ye X, Linton JM, Schork NJ, Buck LB, Petrascheck M Aging cell 24134630 Aging Cell 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24134630
Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms. Solis GM, Kardakaris R, Valentine ER, Bar-Peled L, Chen AL, Blewett MM, McCormick MA, Williamson JR, Kennedy B, Cravatt BF, Petrascheck M eLife 30479271 Elife 2018 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/30479271
Pharmacological classes that extend lifespan of Caenorhabditis elegans. Carretero M, Gomez-Amaro RL, Petrascheck M Frontiers in genetics 25784926 Front Genet 2015 https://www.ncbi.nlm.nih.gov/pubmed/25784926
A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease. Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW Jr, Birnbaumer L, Staruschenko A Journal of the American Society of Nephrology : JASN 29793963 J Am Soc Nephrol 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29793963
Chronic central serotonin depletion attenuates ventilation and body temperature in young but not adult Tph2 knockout rats. Kaplan K, Echert AE, Massat B, Puissant MM, Palygin O, Geurts AM, Hodges MR Journal of applied physiology (Bethesda, Md. : 1985) 26869713 J Appl Physiol (1985) 2016 May 1 https://www.ncbi.nlm.nih.gov/pubmed/26869713
2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research. Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A, International Committee on Standardized Genetic Nomenclature for Mice, Rat Genome and Nomenclature Committee Journal of cardiovascular translational research 25920443 J Cardiovasc Transl Res 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25920443
p66Shc regulates renal vascular tone in hypertension-induced nephropathy. Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW Jr, Geurts AM, Staruschenko A, Imig JD, Sorokin A The Journal of clinical investigation 27270176 J Clin Invest 2016 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/27270176
Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure. Kuijk EW, Rasmussen S, Blokzijl F, Huch M, Gehart H, Toonen P, Begthel H, Clevers H, Geurts AM, Cuppen E Scientific reports 26915950 Sci Rep 2016 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/26915950
Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats. Fan F, Geurts AM, Pabbidi MR, Smith SV, Harder DR, Jacob H, Roman RJ PloS one 25397684 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/25397684
Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cells. Hegan PS, Ostertag E, Geurts AM, Mooseker MS Cytoskeleton (Hoboken, N.J.) 26446290 Cytoskeleton (Hoboken) 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26446290
Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection. Mitzelfelt KA, McDermott-Roe C, Grzybowski MN, Marquez M, Kuo CT, Riedel M, Lai S, Choi MJ, Kolander KD, Helbling D, Dimmock DP, Battle MA, Jou CJ, Tristani-Firouzi M, Verbsky JW, Benjamin IJ, Geurts AM Stem cell reports 28238794 Stem Cell Reports 2017 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/28238794
Identifying multiple causative genes at a single GWAS locus. Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C Genome research 24006081 Genome Res 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/24006081
Rab38 modulates proteinuria in model of hypertension-associated renal disease. Rangel-Filho A, Lazar J, Moreno C, Geurts A, Jacob HJ Journal of the American Society of Nephrology : JASN 23291471 J Am Soc Nephrol 2013 Feb https://www.ncbi.nlm.nih.gov/pubmed/23291471
The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility. Mitzelfelt KA, Limphong P, Choi MJ, Kondrat FD, Lai S, Kolander KD, Kwok WM, Dai Q, Grzybowski MN, Zhang H, Taylor GM, Lui Q, Thao MT, Hudson JA, Barresi R, Bushby K, Jungbluth H, Wraige E, Geurts AM, Benesch JL, Riedel M, Christians ES, Minella AC, Benjamin IJ The Journal of biological chemistry 27226619 J Biol Chem 2016 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/27226619
Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats. Geurts AM, Mattson DL, Liu P, Cabacungan E, Skelton MM, Kurth TM, Yang C, Endres BT, Klotz J, Liang M, Cowley AW Jr Hypertension (Dallas, Tex. : 1979) 25452472 Hypertension 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25452472
CXM: a new tool for mapping breast cancer risk in the tumor microenvironment. Flister MJ, Endres BT, Rudemiller N, Sarkis AB, Santarriaga S, Roy I, Lemke A, Geurts AM, Moreno C, Ran S, Tsaih SW, De Pons J, Carlson DF, Tan W, Fahrenkrug SC, Lazarova Z, Lazar J, North PE, LaViolette PS, Dwinell MB, Shull JD, Jacob HJ Cancer research 25172839 Cancer Res 2014 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/25172839
Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. Endres BT, Priestley JR, Palygin O, Flister MJ, Hoffman MJ, Weinberg BD, Grzybowski M, Lombard JH, Staruschenko A, Moreno C, Jacob HJ, Geurts AM Proceedings of the National Academy of Sciences of the United States of America 25136115 Proc Natl Acad Sci U S A 2014 Sep 2 https://www.ncbi.nlm.nih.gov/pubmed/25136115
Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. Carlson DF, Geurts AM, Garbe JR, Park CW, Rangel-Filho A, O'Grady SM, Jacob HJ, Steer CJ, Largaespada DA, Fahrenkrug SC Transgenic research 20352328 Transgenic Res 2011 Feb https://www.ncbi.nlm.nih.gov/pubmed/20352328
Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension. Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA Purinergic signalling 26385692 Purinergic Signal 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26385692
Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons. Ivics Z, Mátés L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, Bösze Z, Geurts A, Pravenec M, Rülicke T, Izsvák Z Nature protocols 24625778 Nat Protoc 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24625778
Essential role of Kir5.1 channels in renal salt handling and blood pressure control. Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Pochynyuk OM, Jacob HJ, Geurts AM, Hodges MR, Staruschenko A JCI insight 28931751 JCI Insight 2017 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/28931751
Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M Journal of the American Heart Association 26888427 J Am Heart Assoc 2016 Feb 17 https://www.ncbi.nlm.nih.gov/pubmed/26888427
The NRF2 knockout rat: a new animal model to study endothelial dysfunction, oxidant stress, and microvascular rarefaction. Priestley JR, Kautenburg KE, Casati MC, Endres BT, Geurts AM, Lombard JH American journal of physiology. Heart and circulatory physiology 26637559 Am J Physiol Heart Circ Physiol 2016 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/26637559
Intravital imaging of the kidney in a rat model of salt-sensitive hypertension. Endres BT, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Kamocka MM, McDermott-Roe C, Staruschenko A, Molitoris BA, Geurts AM, Palygin O American journal of physiology. Renal physiology 28404591 Am J Physiol Renal Physiol 2017 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/28404591
Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics. Parker CC, Chen H, Flagel SB, Geurts AM, Richards JB, Robinson TE, Solberg Woods LC, Palmer AA Neuropharmacology 23791960 Neuropharmacology 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/23791960
Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats. McPherson KC, Taylor L, Johnson AC, Didion SP, Geurts AM, Garrett MR, Williams JM American journal of physiology. Renal physiology 27465994 Am J Physiol Renal Physiol 2016 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/27465994
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. Katter K, Geurts AM, Hoffmann O, Mátés L, Landa V, Hiripi L, Moreno C, Lazar J, Bashir S, Zidek V, Popova E, Jerchow B, Becker K, Devaraj A, Walter I, Grzybowksi M, Corbett M, Filho AR, Hodges MR, Bader M, Ivics Z, Jacob HJ, Pravenec M, Bosze Z, Rülicke T, Izsvák Z FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23195032 FASEB J 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23195032
Nitric oxide production by glomerular podocytes. Palygin O, Ilatovskaya DV, Levchenko V, Endres BT, Geurts AM, Staruschenko A Nitric oxide : biology and chemistry 29128399 Nitric Oxide 2018 Jan 30 https://www.ncbi.nlm.nih.gov/pubmed/29128399
Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta. Endres BT, Staruschenko A, Schulte M, Geurts AM, Palygin O Journal of visualized experiments : JoVE 26132549 J Vis Exp 2015 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/26132549
Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat. Fan F, Geurts AM, Murphy SR, Pabbidi MR, Jacob HJ, Roman RJ American journal of physiology. Regulatory, integrative and comparative physiology 25540098 Am J Physiol Regul Integr Comp Physiol 2015 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/25540098
A monoclonal antibody that targets a NaV1.7 channel voltage sensor for pain and itch relief. Lee JH, Park CK, Chen G, Han Q, Xie RG, Liu T, Ji RR, Lee SY Cell 24856969 Cell 2014 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/24856969
Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin. Wang C, Chung BC, Yan H, Lee SY, Pitt GS Structure (London, England : 1993) 22705208 Structure 2012 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/22705208
Current view on regulation of voltage-gated sodium channels by calcium and auxiliary proteins. Pitt GS, Lee SY Protein science : a publication of the Protein Society 27262167 Protein Sci 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/27262167
Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å. Johnson ZL, Cheong CG, Lee SY Nature 22407322 Nature 2012 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/22407322
Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation. Wang C, Chung BC, Yan H, Wang HG, Lee SY, Pitt GS Nature communications 25232683 Nat Commun 2014 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/25232683
Cryo-electron microscopy structure of the TRPV2 ion channel. Zubcevic L, Herzik MA Jr, Chung BC, Liu Z, Lander GC, Lee SY Nature structural & molecular biology 26779611 Nat Struct Mol Biol 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26779611
Variability in a Short Tandem Repeat Mediates Complex Epistatic Interactions in Arabidopsis thaliana. Press MO, Queitsch C Genetics 27866166 Genetics 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27866166
The Mechanistic Underpinnings of an ago1-Mediated, Environmentally Dependent, and Stochastic Phenotype. Mason GA, Lemus T, Queitsch C Plant physiology 26872948 Plant Physiol 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26872948
Background-dependent effects of polyglutamine variation in the Arabidopsis thaliana gene ELF3. Undurraga SF, Press MO, Legendre M, Bujdoso N, Bale J, Wang H, Davis SJ, Verstrepen KJ, Queitsch C Proceedings of the National Academy of Sciences of the United States of America 23129635 Proc Natl Acad Sci U S A 2012 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/23129635
Molecular mechanisms governing differential robustness of development and environmental responses in plants. Lachowiec J, Queitsch C, Kliebenstein DJ Annals of botany 26473020 Ann Bot 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26473020
Redundancy, Feedback, and Robustness in the Arabidopsis thaliana BZR/BEH Gene Family. Lachowiec J, Mason GA, Schultz K, Queitsch C Frontiers in genetics 30542366 Front Genet 2018 https://www.ncbi.nlm.nih.gov/pubmed/30542366
It's not magic - Hsp90 and its effects on genetic and epigenetic variation. Zabinsky RA, Mason GA, Queitsch C, Jarosz DF Seminars in cell & developmental biology 29807130 Semin Cell Dev Biol 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/29807130
Molecular mechanisms of robustness in plants. Lempe J, Lachowiec J, Sullivan AM, Queitsch C Current opinion in plant biology 23279801 Curr Opin Plant Biol 2013 Feb https://www.ncbi.nlm.nih.gov/pubmed/23279801
The protein chaperone HSP90 can facilitate the divergence of gene duplicates. Lachowiec J, Lemus T, Thomas JH, Murphy PJ, Nemhauser JL, Queitsch C Genetics 23410833 Genetics 2013 Apr https://www.ncbi.nlm.nih.gov/pubmed/23410833
Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. Xia J, Chiu LY, Nehring RB, Bravo Núñez MA, Mei Q, Perez M, Zhai Y, Fitzgerald DM, Pribis JP, Wang Y, Hu CW, Powell RT, LaBonte SA, Jalali A, Matadamas Guzmán ML, Lentzsch AM, Szafran AT, Joshi MC, Richters M, Gibson JL, Frisch RL, Hastings PJ, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C, Miller KM, Rosenberg SM Cell 30633903 Cell 2019 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/30633903
Corrigendum: MIPSTR: a method for multiplex genotyping of germline and somatic STR variation across many individuals. Carlson KD, Sudmant PH, Press MO, Eichler EE, Shendure J, Queitsch C Genome research 26240161 Genome Res 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26240161
Evolutionary assembly patterns of prokaryotic genomes. Press MO, Queitsch C, Borenstein E Genome research 27197212 Genome Res 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27197212
The overdue promise of short tandem repeat variation for heritability. Press MO, Carlson KD, Queitsch C Trends in genetics : TIG 25182195 Trends Genet 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25182195
Hsp90 promotes kinase evolution. Lachowiec J, Lemus T, Borenstein E, Queitsch C Molecular biology and evolution 25246701 Mol Biol Evol 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25246701
Lessons from model organisms: phenotypic robustness and missing heritability in complex disease. Queitsch C, Carlson KD, Girirajan S PLoS genetics 23166511 PLoS Genet 2012 https://www.ncbi.nlm.nih.gov/pubmed/23166511
Medicine. Combating evolution to fight disease. Rosenberg SM, Queitsch C Science (New York, N.Y.) 24604189 Science 2014 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/24604189
Genome-scale co-evolutionary inference identifies functions and clients of bacterial Hsp90. Press MO, Li H, Creanza N, Kramer G, Queitsch C, Sourjik V, Borenstein E PLoS genetics 23874229 PLoS Genet 2013 https://www.ncbi.nlm.nih.gov/pubmed/23874229
AGO1 and HSP90 buffer different genetic variants in Arabidopsis thaliana. Lemus T, Mason GA, Bubb KL, Alexandre CM, Queitsch C, Cuperus JT Genetics 36303325 Genetics 2023 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/36303325
Massive variation of short tandem repeats with functional consequences across strains of Arabidopsis thaliana. Press MO, McCoy RC, Hall AN, Akey JM, Queitsch C Genome research 29970452 Genome Res 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29970452
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GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris. Liachko I, Youngblood RA, Tsui K, Bubb KL, Queitsch C, Raghuraman MK, Nislow C, Brewer BJ, Dunham MJ PLoS genetics 24603708 PLoS Genet 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24603708
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A Genome-Wide Association Analysis Reveals Epistatic Cancellation of Additive Genetic Variance for Root Length in Arabidopsis thaliana. Lachowiec J, Shen X, Queitsch C, Carlborg Ö PLoS genetics 26397943 PLoS Genet 2015 https://www.ncbi.nlm.nih.gov/pubmed/26397943
HSP90 Contributes to Entrainment of the Arabidopsis Circadian Clock via the Morning Loop. Davis AM, Ronald J, Ma Z, Wilkinson AJ, Philippou K, Shindo T, Queitsch C, Davis SJ Genetics 30337341 Genetics 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30337341
MIPSTR: a method for multiplex genotyping of germline and somatic STR variation across many individuals. Carlson KD, Sudmant PH, Press MO, Eichler EE, Shendure J, Queitsch C Genome research 25659649 Genome Res 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25659649
REDOR NMR for drug discovery. Cegelski L Bioorganic & medicinal chemistry letters 24035486 Bioorg Med Chem Lett 2013 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/24035486
Dimethyl sulfoxide and ethanol elicit increased amyloid biogenesis and amyloid-integrated biofilm formation in Escherichia coli. Lim JY, May JM, Cegelski L Applied and environmental microbiology 22389366 Appl Environ Microbiol 2012 May https://www.ncbi.nlm.nih.gov/pubmed/22389366
Cell-Based High-Throughput Screening Identifies Rifapentine as an Inhibitor of Amyloid and Biofilm Formation in Escherichia coli. Maher MC, Lim JY, Gunawan C, Cegelski L ACS infectious diseases 27623312 ACS Infect Dis 2015 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/27623312
Curcumin as an amyloid-indicator dye in E. coli. McCrate OA, Zhou X, Cegelski L Chemical communications (Cambridge, England) 23287899 Chem Commun (Camb) 2013 May 14 https://www.ncbi.nlm.nih.gov/pubmed/23287899
Sum of the parts: composition and architecture of the bacterial extracellular matrix. McCrate OA, Zhou X, Reichhardt C, Cegelski L Journal of molecular biology 23827139 J Mol Biol 2013 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/23827139
Nutrient-dependent structural changes in S. aureus peptidoglycan revealed by solid-state NMR spectroscopy. Zhou X, Cegelski L Biochemistry 22974326 Biochemistry 2012 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/22974326
Quantitative analysis of amyloid-integrated biofilms formed by uropathogenic Escherichia coli at the air-liquid interface. Wu C, Lim JY, Fuller GG, Cegelski L Biophysical journal 22947862 Biophys J 2012 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/22947862
Disruption of Escherichia coli amyloid-integrated biofilm formation at the air-liquid interface by a polysorbate surfactant. Wu C, Lim JY, Fuller GG, Cegelski L Langmuir : the ACS journal of surfaces and colloids 23259693 Langmuir 2013 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/23259693
Analysis of the Aspergillus fumigatus Biofilm Extracellular Matrix by Solid-State Nuclear Magnetic Resonance Spectroscopy. Reichhardt C, Ferreira JA, Joubert LM, Clemons KV, Stevens DA, Cegelski L Eukaryotic cell 26163318 Eukaryot Cell 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26163318
Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR. Nygaard R, Romaniuk JAH, Rice DM, Cegelski L Biophysical journal 25809251 Biophys J 2015 Mar 24 https://www.ncbi.nlm.nih.gov/pubmed/25809251
Toward a biorelevant structure of protein kinase C bound modulators: design, synthesis, and evaluation of labeled bryostatin analogues for analysis with rotational echo double resonance NMR spectroscopy. Loy BA, Lesser AB, Staveness D, Billingsley KL, Cegelski L, Wender PA Journal of the American Chemical Society 25710634 J Am Chem Soc 2015 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/25710634
Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR. Romaniuk JA, Cegelski L Philosophical transactions of the Royal Society of London. Series B, Biological sciences 26370936 Philos Trans R Soc Lond B Biol Sci 2015 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/26370936
Bottom-up and top-down solid-state NMR approaches for bacterial biofilm matrix composition. Cegelski L Journal of magnetic resonance (San Diego, Calif. : 1997) 25797008 J Magn Reson 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25797008
Community behavior and amyloid-associated phenotypes among a panel of uropathogenic E. coli. Lim JY, Pinkner JS, Cegelski L Biochemical and biophysical research communications 24239885 Biochem Biophys Res Commun 2014 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/24239885
Solid-State NMR for Bacterial Biofilms. Reichhardt C, Cegelski L Molecular physics 24976646 Mol Phys 2014 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/24976646
Putative hydrogen bond to tyrosine M208 in photosynthetic reaction centers from Rhodobacter capsulatus significantly slows primary charge separation. Saggu M, Carter B, Zhou X, Faries K, Cegelski L, Holten D, Boxer SG, Kirmaier C The journal of physical chemistry. B 24902471 J Phys Chem B 2014 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/24902471
Characterization of the Vibrio cholerae extracellular matrix: a top-down solid-state NMR approach. Reichhardt C, Fong JC, Yildiz F, Cegelski L Biochimica et biophysica acta 24911407 Biochim Biophys Acta 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/24911407
Frequency-selective REDOR and spin-diffusion relays in uniformly labeled whole cells. Rice DM, Romaniuk JA, Cegelski L Solid state nuclear magnetic resonance 26493462 Solid State Nucl Magn Reson 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26493462
Molecular determinants of mechanical properties of V. cholerae biofilms at the air-liquid interface. Hollenbeck EC, Fong JC, Lim JY, Yildiz FH, Fuller GG, Cegelski L Biophysical journal 25418293 Biophys J 2014 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/25418293
Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Tucker BA, Anfinson KR, Mullins RF, Stone EM, Young MJ Stem cells translational medicine 23283489 Stem Cells Transl Med 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/23283489
Intravesical and alternative bladder-preservation therapies in the management of non-muscle-invasive bladder cancer unresponsive to bacillus Calmette-Guérin. Steinberg RL, Thomas LJ, Nepple KG Urologic oncology 26777259 Urol Oncol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/26777259
SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. Ozden O, Park SH, Wagner BA, Song HY, Zhu Y, Vassilopoulos A, Jung B, Buettner GR, Gius D Free radical biology & medicine 25152236 Free Radic Biol Med 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25152236
Is age-related macular degeneration a microvascular disease? Mullins RF, Khanna A, Schoo DP, Tucker BA, Sohn EH, Drack AV, Stone EM Advances in experimental medicine and biology 24664709 Adv Exp Med Biol 2014 https://www.ncbi.nlm.nih.gov/pubmed/24664709
CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype. Burnight ER, Wiley LA, Drack AV, Braun TA, Anfinson KR, Kaalberg EE, Halder JA, Affatigato LM, Mullins RF, Stone EM, Tucker BA Gene therapy 24807808 Gene Ther 2014 Jul https://www.ncbi.nlm.nih.gov/pubmed/24807808
Stem cells for investigation and treatment of inherited retinal disease. Tucker BA, Mullins RF, Stone EM Human molecular genetics 24647603 Hum Mol Genet 2014 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/24647603
Prognostic factors for survival in patients with high-grade osteosarcoma using the Surveillance, Epidemiology, and End Results (SEER) Program database. Duchman KR, Gao Y, Miller BJ Cancer epidemiology 26002013 Cancer Epidemiol 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26002013
Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration. Songstad AE, Wiley LA, Duong K, Kaalberg E, Flamme-Wiese MJ, Cranston CM, Riker MJ, Levasseur D, Stone EM, Mullins RF, Tucker BA Investigative ophthalmology & visual science 26720480 Invest Ophthalmol Vis Sci 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26720480
Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease. Giacalone JC, Wiley LA, Burnight ER, Songstad AE, Mullins RF, Stone EM, Tucker BA Stem cells translational medicine 26683869 Stem Cells Transl Med 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26683869
Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds. Worthington KS, Wiley LA, Guymon CA, Salem AK, Tucker BA Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 26692377 J Ocul Pharmacol Ther 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/26692377
Molecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration. Zeng S, Whitmore SS, Sohn EH, Riker MJ, Wiley LA, Scheetz TE, Stone EM, Tucker BA, Mullins RF The Journal of pathology 26564985 J Pathol 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26564985
Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. Tucker BA, Mullins RF, Streb LM, Anfinson K, Eyestone ME, Kaalberg E, Riker MJ, Drack AV, Braun TA, Stone EM eLife 23991284 Elife 2013 Aug 27 https://www.ncbi.nlm.nih.gov/pubmed/23991284
Vending Assessment and Program Implementation in Four Iowa Worksites. Lillehoj CJ, Nothwehr F, Shipley K, Voss C Health promotion practice 26220278 Health Promot Pract 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26220278
Controlled drug delivery from 3D printed two-photon polymerized poly(ethylene glycol) dimethacrylate devices. Do AV, Worthington KS, Tucker BA, Salem AK International journal of pharmaceutics 30268853 Int J Pharm 2018 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/30268853
Gene therapy using stem cells. Burnight ER, Wiley LA, Mullins RF, Stone EM, Tucker BA Cold Spring Harbor perspectives in medicine 25395375 Cold Spring Harb Perspect Med 2014 Nov 13 https://www.ncbi.nlm.nih.gov/pubmed/25395375
Allogenic iPSC-derived RPE cell transplants induce immune response in pigs: a pilot study. Sohn EH, Jiao C, Kaalberg E, Cranston C, Mullins RF, Stone EM, Tucker BA Scientific reports 26138532 Sci Rep 2015 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/26138532
Perception of patient appearance following various methods of reconstruction after orbital exenteration. Kuiper JJ, Zimmerman MB, Pagedar NA, Carter KD, Allen RC, Shriver EM Orbit (Amsterdam, Netherlands) 27341072 Orbit 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27341072
Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy. Whitmore SS, Sohn EH, Chirco KR, Drack AV, Stone EM, Tucker BA, Mullins RF Progress in retinal and eye research 25486088 Prog Retin Eye Res 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25486088
Mechanical properties of murine and porcine ocular tissues in compression. Worthington KS, Wiley LA, Bartlett AM, Stone EM, Mullins RF, Salem AK, Guymon CA, Tucker BA Experimental eye research 24613781 Exp Eye Res 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24613781
ABCB5 is a limbal stem cell gene required for corneal development and repair. Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY Nature 25030174 Nature 2014 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/25030174
Sources of bias in peoples' social-comparative estimates of food consumption. Scherer AM, Bruchmann K, Windschitl PD, Rose JP, Smith AR, Koestner B, Snetselaar L, Suls J Journal of experimental psychology. Applied 27054551 J Exp Psychol Appl 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27054551
Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases. Wiley LA, Burnight ER, Songstad AE, Drack AV, Mullins RF, Stone EM, Tucker BA Progress in retinal and eye research 25448922 Prog Retin Eye Res 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25448922
Stem cells as tools for studying the genetics of inherited retinal degenerations. Wiley LA, Burnight ER, Mullins RF, Stone EM, Tucker BA Cold Spring Harbor perspectives in medicine 25502747 Cold Spring Harb Perspect Med 2014 Dec 11 https://www.ncbi.nlm.nih.gov/pubmed/25502747
Natural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy. Boye SE, Huang WC, Roman AJ, Sumaroka A, Boye SL, Ryals RC, Olivares MB, Ruan Q, Tucker BA, Stone EM, Swaroop A, Cideciyan AV, Hauswirth WW, Jacobson SG PloS one 24671090 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/24671090
The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning. Mullins RF, Schoo DP, Sohn EH, Flamme-Wiese MJ, Workamelahu G, Johnston RM, Wang K, Tucker BA, Stone EM The American journal of pathology 25204844 Am J Pathol 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25204844
Structural and biochemical analyses of choroidal thickness in human donor eyes. Sohn EH, Khanna A, Tucker BA, Abràmoff MD, Stone EM, Mullins RF Investigative ophthalmology & visual science 24519422 Invest Ophthalmol Vis Sci 2014 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/24519422
Use of the Teres Major Muscle in Chimeric Subscapular System Free Flaps for Head and Neck Reconstruction. Tomlinson AR, Jameson MJ, Pagedar NA, Schoeff SS, Shearer AE, Boyd NH JAMA otolaryngology-- head & neck surgery 26312435 JAMA Otolaryngol Head Neck Surg 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26312435
Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis. DeLuca AP, Whitmore SS, Barnes J, Sharma TP, Westfall TA, Scott CA, Weed MC, Wiley JS, Wiley LA, Johnston RM, Schnieders MJ, Lentz SR, Tucker BA, Mullins RF, Scheetz TE, Stone EM, Slusarski DC Human molecular genetics 26494905 Hum Mol Genet 2016 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/26494905
Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease. Braun TA, Mullins RF, Wagner AH, Andorf JL, Johnston RM, Bakall BB, Deluca AP, Fishman GA, Lam BL, Weleber RG, Cideciyan AV, Jacobson SG, Sheffield VC, Tucker BA, Stone EM Human molecular genetics 23918662 Hum Mol Genet 2013 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/23918662
Two-Photon Polymerization as a Tool for Studying 3D Printed Topography-Induced Stem Cell Fate. Worthington KS, Do AV, Smith R, Tucker BA, Salem AK Macromolecular bioscience 30430755 Macromol Biosci 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30430755
Weight loss after head and neck cancer: A dynamic relationship with depressive symptoms. Van Liew JR, Brock RL, Christensen AJ, Karnell LH, Pagedar NA, Funk GF Head & neck 27704695 Head Neck 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/27704695
A Method for Sectioning and Immunohistochemical Analysis of Stem Cell-Derived 3-D Organoids. Wiley LA, Beebe DC, Mullins RF, Stone EM, Tucker BA Current protocols in stem cell biology 27171793 Curr Protoc Stem Cell Biol 2016 May 12 https://www.ncbi.nlm.nih.gov/pubmed/27171793
Photoreceptor cells with profound structural deficits can support useful vision in mice. Thompson S, Blodi FR, Lee S, Welder CR, Mullins RF, Tucker BA, Stasheff SF, Stone EM Investigative ophthalmology & visual science 24569582 Invest Ophthalmol Vis Sci 2014 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/24569582
Low-oxygen culture conditions extend the multipotent properties of human retinal progenitor cells. Baranov PY, Tucker BA, Young MJ Tissue engineering. Part A 24320879 Tissue Eng Part A 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24320879
Loss of CD34 expression in aging human choriocapillaris endothelial cells. Sohn EH, Flamme-Wiese MJ, Whitmore SS, Wang K, Tucker BA, Mullins RF PloS one 24466138 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/24466138
Risk of recurrent preterm birth among women according to change in partner. Baer RJ, Yang J, Chambers CD, Ryckman KK, Saftlas AF, Berghella V, Schetter CD, Shaw GM, Stevenson DK, Jelliffe-Pawlowski LL Journal of perinatal medicine 27718495 J Perinat Med 2017 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/27718495
Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma. Tucker BA, Solivan-Timpe F, Roos BR, Anfinson KR, Robin AL, Wiley LA, Mullins RF, Fingert JH Journal of stem cell research & therapy 24883232 J Stem Cell Res Ther 2014 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/24883232
Treatment and Survival Trends in Glottic Carcinoma in Situ and Stage I Cancer From 1988 to 2012. Khaja SF, Hoffman HT, Pagedar NA The Annals of otology, rhinology, and laryngology 26481178 Ann Otol Rhinol Laryngol 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26481178
cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Wiley LA, Burnight ER, DeLuca AP, Anfinson KR, Cranston CM, Kaalberg EE, Penticoff JA, Affatigato LM, Mullins RF, Stone EM, Tucker BA Scientific reports 27471043 Sci Rep 2016 Jul 29 https://www.ncbi.nlm.nih.gov/pubmed/27471043
Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa. Tucker BA, Scheetz TE, Mullins RF, DeLuca AP, Hoffmann JM, Johnston RM, Jacobson SG, Sheffield VC, Stone EM Proceedings of the National Academy of Sciences of the United States of America 21825139 Proc Natl Acad Sci U S A 2011 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/21825139
Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis. Drivas TG, Wojno AP, Tucker BA, Stone EM, Bennett J Science translational medicine 26062849 Sci Transl Med 2015 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/26062849
Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq. Whitmore SS, Wagner AH, DeLuca AP, Drack AV, Stone EM, Tucker BA, Zeng S, Braun TA, Mullins RF, Scheetz TE Experimental eye research 25446321 Exp Eye Res 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25446321
Using patient-specific induced pluripotent stem cells to interrogate the pathogenicity of a novel retinal pigment epithelium-specific 65 kDa cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial. Tucker BA, Cranston CM, Anfinson KA, Shrestha S, Streb LM, Leon A, Mullins RF, Stone EM Translational research : the journal of laboratory and clinical medicine 26364624 Transl Res 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26364624
Prevascularized silicon membranes for the enhancement of transport to implanted medical devices. Worthington KS, Wiley LA, Mullins RF, Tucker BA, Nuxoll E Journal of biomedical materials research. Part B, Applied biomaterials 26316050 J Biomed Mater Res B Appl Biomater 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/26316050
Influence of a loop electrosurgical excision procedure (LEEP) on levels of cytokines in cervical secretions. Saftlas AF, Spracklen CN, Ryckman KK, Stockdale CK, Penrose K, Ault K, Rubenstein LM, Pinto LA Journal of reproductive immunology 25721621 J Reprod Immunol 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25721621
Velocity profiles in pores with undulating opening diameter and their importance for resistive-pulse experiments. Innes LM, Chen CH, Schiel M, Pevarnik M, Haurais F, Toimil-Molares ME, Vlassiouk I, Theogarajan L, Siwy ZS Analytical chemistry 25245282 Anal Chem 2014 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/25245282
Tailored Polymeric Membranes for Mycobacterium Smegmatis Porin A (MspA) Based Biosensors. Morton D, Mortezaei S, Yemenicioglu S, Isaacman MJ, Nova IC, Gundlach JH, Theogarajan L Journal of materials chemistry. B 26413301 J Mater Chem B 2015 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/26413301
Solid-state nanopore based biomimetic voltage gated ion channels. Pevarnik M, Cui W, Yemenicioglu S, Rofeh J, Theogarajan L Bioinspiration & biomimetics 28726670 Bioinspir Biomim 2017 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/28726670
Wafer Scale Integration of CMOS Chips for Biomedical Applications via Self-Aligned Masking. Uddin A, Milaninia K, Chen CH, Theogarajan L IEEE transactions on components, packaging, and manufacturing technology 22400126 IEEE Trans Compon Packaging Manuf Technol 2011 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/22400126
A CMOS enhanced solid-state nanopore based single molecule detection platform. Chen C, Yemenicioglu S, Uddin A, Corgliano E, Theogarajan L Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 24109650 Annu Int Conf IEEE Eng Med Biol Soc 2013 https://www.ncbi.nlm.nih.gov/pubmed/24109650
Clickable Amphiphilic Triblock Copolymers. Isaacman MJ, Barron KA, Theogarajan LS Journal of polymer science. Part A, Polymer chemistry 23100856 J Polym Sci A Polym Chem 2012 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/23100856
Rapid Metal -free Macromolecular Coupling via in situ Nitrile Oxide-Activated Alkene Cycloaddition. Isaacman MJ, Cui W, Theogarajan LS Journal of polymer science. Part A, Polymer chemistry 26811566 J Polym Sci A Polym Chem 2014 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/26811566
Integration of solid-state nanopores in a 0.5 μm CMOS foundry process. Uddin A, Yemenicioglu S, Chen CH, Corigliano E, Milaninia K, Theogarajan L Nanotechnology 23519330 Nanotechnology 2013 Apr 19 https://www.ncbi.nlm.nih.gov/pubmed/23519330
Stealth polymeric vesicles via metal-free click coupling. Isaacman MJ, Corigliano EM, Theogarajan LS Biomacromolecules 23952743 Biomacromolecules 2013 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/23952743
Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease. Yoruk B, Gillers BS, Chi NC, Scott IC Developmental biology 22182521 Dev Biol 2012 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/22182521
Zebrafish cardiac injury and regeneration models: a noninvasive and invasive in vivo model of cardiac regeneration. Dickover MS, Zhang R, Han P, Chi NC Methods in molecular biology (Clifton, N.J.) 24029953 Methods Mol Biol 2013 https://www.ncbi.nlm.nih.gov/pubmed/24029953
Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure. Hashem SI, Perry CN, Bauer M, Han S, Clegg SD, Ouyang K, Deacon DC, Spinharney M, Panopoulos AD, Izpisua Belmonte JC, Frazer KA, Chen J, Gong Q, Zhou Z, Chi NC, Adler ED Stem cells (Dayton, Ohio) 25826782 Stem Cells 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/25826782
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The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Dickover M, Hegarty JM, Ly K, Lopez D, Yang H, Zhang R, Tedeschi N, Hsiai TK, Chi NC Developmental biology 24607366 Dev Biol 2014 May 15 https://www.ncbi.nlm.nih.gov/pubmed/24607366
Zebrafish models in cardiac development and congenital heart birth defects. Tu S, Chi NC Differentiation; research in biological diversity 22704690 Differentiation 2012 Jul https://www.ncbi.nlm.nih.gov/pubmed/22704690
Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function. Palencia-Desai S, Kohli V, Kang J, Chi NC, Black BL, Sumanas S Development (Cambridge, England) 21989916 Development 2011 Nov https://www.ncbi.nlm.nih.gov/pubmed/21989916
Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development. Yang H, Fang L, Zhan R, Hegarty JM, Ren J, Hsiai TK, Gleeson JG, Miller YI, Trejo J, Chi NC Developmental biology 26004360 Dev Biol 2015 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/26004360
Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Xie W, Schultz MD, Lister R, Hou Z, Rajagopal N, Ray P, Whitaker JW, Tian S, Hawkins RD, Leung D, Yang H, Wang T, Lee AY, Swanson SA, Zhang J, Zhu Y, Kim A, Nery JR, Urich MA, Kuan S, Yen CA, Klugman S, Yu P, Suknuntha K, Propson NE, Chen H, Edsall LE, Wagner U, Li Y, Ye Z, Kulkarni A, Xuan Z, Chung WY, Chi NC, Antosiewicz-Bourget JE, Slukvin I, Stewart R, Zhang MQ, Wang W, Thomson JA, Ecker JR, Ren B Cell 23664764 Cell 2013 May 23 https://www.ncbi.nlm.nih.gov/pubmed/23664764
Wearable multi-channel microelectrode membranes for elucidating electrophysiological phenotypes of injured myocardium. Cao H, Yu F, Zhao Y, Zhang X, Tai J, Lee J, Darehzereshki A, Bersohn M, Lien CL, Chi NC, Tai YC, Hsiai TK Integrative biology : quantitative biosciences from nano to macro 24945366 Integr Biol (Camb) 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24945366
Myocardial plasticity: cardiac development, regeneration and disease. Bloomekatz J, Galvez-Santisteban M, Chi NC Current opinion in genetics & development 27498024 Curr Opin Genet Dev 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27498024
Disease Burden and Symptom Structure of Autism in Neurofibromatosis Type 1: A Study of the International NF1-ASD Consortium Team (INFACT). Morris SM, Acosta MT, Garg S, Green J, Huson S, Legius E, North KN, Payne JM, Plasschaert E, Frazier TW, Weiss LA, Zhang Y, Gutmann DH, Constantino JN JAMA psychiatry 27760236 JAMA Psychiatry 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27760236
Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. Deshpande A, Yadav S, Dao DQ, Wu ZY, Hokanson KC, Cahill MK, Wiita AP, Jan YN, Ullian EM, Weiss LA Cell reports 29212016 Cell Rep 2017 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/29212016
Age and ASD symptoms in Costello syndrome. Young O, Perati S, Weiss LA, Rauen KA American journal of medical genetics. Part A 29575620 Am J Med Genet A 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29575620
Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Josowitz R, Mulero-Navarro S, Rodriguez NA, Falce C, Cohen N, Ullian EM, Weiss LA, Rauen KA, Sobie EA, Gelb BD Stem cell reports 27569062 Stem Cell Reports 2016 Sep 13 https://www.ncbi.nlm.nih.gov/pubmed/27569062
Craniofacial and dental development in cardio-facio-cutaneous syndrome: the importance of Ras signaling homeostasis. Goodwin AF, Oberoi S, Landan M, Charles C, Groth J, Martinez A, Fairley C, Weiss LA, Tidyman WE, Klein OD, Rauen KA Clinical genetics 22946697 Clin Genet 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/22946697
Dysregulation of astrocyte extracellular signaling in Costello syndrome. Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney GE, Rauen KA, Weiss LA, Rowitch DH, Ullian EM Science translational medicine 25947161 Sci Transl Med 2015 May 6 https://www.ncbi.nlm.nih.gov/pubmed/25947161
Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM The Journal of neuroscience : the official journal of the Society for Neuroscience 26740656 J Neurosci 2016 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/26740656
Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders. Mitra I, Lavillaureix A, Yeh E, Traglia M, Tsang K, Bearden CE, Rauen KA, Weiss LA PLoS genetics 28076348 PLoS Genet 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/28076348
Autism traits in the RASopathies. Adviento B, Corbin IL, Widjaja F, Desachy G, Enrique N, Rosser T, Risi S, Marco EJ, Hendren RL, Bearden CE, Rauen KA, Weiss LA Journal of medical genetics 24101678 J Med Genet 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/24101678
Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment. Yeh E, Dao DQ, Wu ZY, Kandalam SM, Camacho FM, Tom C, Zhang W, Krencik R, Rauen KA, Ullian EM, Weiss LA Molecular psychiatry 29158583 Mol Psychiatry 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29158583
RASopathies are associated with a distinct personality profile. Bizaoui V, Gage J, Brar R, Rauen KA, Weiss LA American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 29659143 Am J Med Genet B Neuropsychiatr Genet 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29659143
Global turnover of histone post-translational modifications and variants in human cells. Zee BM, Levin RS, DiMaggio PA, Garcia BA Epigenetics & chromatin 21134274 Epigenetics Chromatin 2010 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/21134274
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K Nature cell biology 23748610 Nat Cell Biol 2013 Jul https://www.ncbi.nlm.nih.gov/pubmed/23748610
A Novel Quantitative Mass Spectrometry Platform for Determining Protein O-GlcNAcylation Dynamics. Wang X, Yuan ZF, Fan J, Karch KR, Ball LE, Denu JM, Garcia BA Molecular & cellular proteomics : MCP 27114449 Mol Cell Proteomics 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27114449
Quantitative proteomic analysis of histone modifications. Huang H, Lin S, Garcia BA, Zhao Y Chemical reviews 25688442 Chem Rev 2015 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/25688442
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. Kanno T, Kanno Y, LeRoy G, Campos E, Sun HW, Brooks SR, Vahedi G, Heightman TD, Garcia BA, Reinberg D, Siebenlist U, O'Shea JJ, Ozato K Nature structural & molecular biology 25383670 Nat Struct Mol Biol 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25383670
In vivo proximity labeling for the detection of protein-protein and protein-RNA interactions. Beck DB, Narendra V, Drury WJ 3rd, Casey R, Jansen PW, Yuan ZF, Garcia BA, Vermeulen M, Bonasio R Journal of proteome research 25311790 J Proteome Res 2014 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/25311790
Post-Translational Modification Profiling--a High-Content Assay for Identifying Protein Modifications in Mammalian Cellular Systems. Merbl Y, Kirschner MW Current protocols in protein science 25081743 Curr Protoc Protein Sci 2014 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/25081743
A proteomic glimpse into the initial global epigenetic changes during HIV infection. Britton LM, Sova P, Belisle S, Liu S, Chan EY, Katze MG, Garcia BA Proteomics 25116026 Proteomics 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25116026
PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism. Jain SU, Do TJ, Lund PJ, Rashoff AQ, Diehl KL, Cieslik M, Bajic A, Juretic N, Deshmukh S, Venneti S, Muir TW, Garcia BA, Jabado N, Lewis PW Nature communications 31086175 Nat Commun 2019 May 13 https://www.ncbi.nlm.nih.gov/pubmed/31086175
LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. Nguyen H, Allali-Hassani A, Antonysamy S, Chang S, Chen LH, Curtis C, Emtage S, Fan L, Gheyi T, Li F, Liu S, Martin JR, Mendel D, Olsen JB, Pelletier L, Shatseva T, Wu S, Zhang FF, Arrowsmith CH, Brown PJ, Campbell RM, Garcia BA, Barsyte-Lovejoy D, Mader M, Vedadi M The Journal of biological chemistry 25825497 J Biol Chem 2015 May 29 https://www.ncbi.nlm.nih.gov/pubmed/25825497
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Chicas A, Kapoor A, Wang X, Aksoy O, Evertts AG, Zhang MQ, Garcia BA, Bernstein E, Lowe SW Proceedings of the National Academy of Sciences of the United States of America 22615382 Proc Natl Acad Sci U S A 2012 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/22615382
Comprehending dynamic protein methylation with mass spectrometry. Afjehi-Sadat L, Garcia BA Current opinion in chemical biology 23333572 Curr Opin Chem Biol 2013 Feb https://www.ncbi.nlm.nih.gov/pubmed/23333572
Asymmetrically modified nucleosomes. Voigt P, LeRoy G, Drury WJ 3rd, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D Cell 23021224 Cell 2012 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/23021224
Breaking the histone code with quantitative mass spectrometry. Britton LM, Gonzales-Cope M, Zee BM, Garcia BA Expert review of proteomics 21999833 Expert Rev Proteomics 2011 Oct https://www.ncbi.nlm.nih.gov/pubmed/21999833
Proteomic interrogation of human chromatin. Torrente MP, Zee BM, Young NL, Baliban RC, LeRoy G, Floudas CA, Hake SB, Garcia BA PloS one 21935452 PLoS One 2011 https://www.ncbi.nlm.nih.gov/pubmed/21935452
Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression. Peixoto LL, Wimmer ME, Poplawski SG, Tudor JC, Kenworthy CA, Liu S, Mizuno K, Garcia BA, Zhang NR, Giese K, Abel T BMC genomics 26040834 BMC Genomics 2015 https://www.ncbi.nlm.nih.gov/pubmed/26040834
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, Hother C, Liu S, Cao XJ, Tam W, Shaknovich R, Garcia BA, Gascoyne RD, Ge K, Shilatifard A, Elemento O, Nussenzweig A, Melnick AM, Wendel HG Nature medicine 26366710 Nat Med 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26366710
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression. Jain SU, Khazaei S, Marchione DM, Lundgren SM, Wang X, Weinberg DN, Deshmukh S, Juretic N, Lu C, Allis CD, Garcia BA, Jabado N, Lewis PW Proceedings of the National Academy of Sciences of the United States of America 33067396 Proc Natl Acad Sci U S A 2020 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/33067396
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Vedadi M, Barsyte-Lovejoy D, Liu F, Rival-Gervier S, Allali-Hassani A, Labrie V, Wigle TJ, Dimaggio PA, Wasney GA, Siarheyeva A, Dong A, Tempel W, Wang SC, Chen X, Chau I, Mangano TJ, Huang XP, Simpson CD, Pattenden SG, Norris JL, Kireev DB, Tripathy A, Edwards A, Roth BL, Janzen WP, Garcia BA, Petronis A, Ellis J, Brown PJ, Frye SV, Arrowsmith CH, Jin J Nature chemical biology 21743462 Nat Chem Biol 2011 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/21743462
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. Ratnakumar K, Duarte LF, LeRoy G, Hasson D, Smeets D, Vardabasso C, Bönisch C, Zeng T, Xiang B, Zhang DY, Li H, Wang X, Hake SB, Schermelleh L, Garcia BA, Bernstein E Genes & development 22391447 Genes Dev 2012 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/22391447
The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Wu L, Zee BM, Wang Y, Garcia BA, Dou Y Molecular cell 21726816 Mol Cell 2011 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/21726816
High resolution is not a strict requirement for characterization and quantification of histone post-translational modifications. Karch KR, Zee BM, Garcia BA Journal of proteome research 25325711 J Proteome Res 2014 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/25325711
Low Resolution Data-Independent Acquisition in an LTQ-Orbitrap Allows for Simplified and Fully Untargeted Analysis of Histone Modifications. Sidoli S, Simithy J, Karch KR, Kulej K, Garcia BA Analytical chemistry 26505526 Anal Chem 2015 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/26505526
Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations. Önder Ö, Sidoli S, Carroll M, Garcia BA Expert review of proteomics 26400466 Expert Rev Proteomics 2015 https://www.ncbi.nlm.nih.gov/pubmed/26400466
Heavy methyl-SILAC labeling coupled with liquid chromatography and high-resolution mass spectrometry to study the dynamics of site-specific histone methylation. Cao XJ, Zee BM, Garcia BA Methods in molecular biology (Clifton, N.J.) 23436372 Methods Mol Biol 2013 https://www.ncbi.nlm.nih.gov/pubmed/23436372
Large-scale global identification of protein lysine methylation in vivo. Cao XJ, Arnaudo AM, Garcia BA Epigenetics 23644510 Epigenetics 2013 May https://www.ncbi.nlm.nih.gov/pubmed/23644510
Validation of protein acetylation by mass spectrometry. Zee BM, Garcia BA Methods in molecular biology (Clifton, N.J.) 23381849 Methods Mol Biol 2013 https://www.ncbi.nlm.nih.gov/pubmed/23381849
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, Gozani O Nature 24847881 Nature 2014 Jun 12 https://www.ncbi.nlm.nih.gov/pubmed/24847881
Middle-Down and Top-Down Mass Spectrometric Analysis of Co-occurring Histone Modifications. Molden RC, Garcia BA Current protocols in protein science 25081742 Curr Protoc Protein Sci 2014 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/25081742
Evaluation of proteomic search engines for the analysis of histone modifications. Yuan ZF, Lin S, Molden RC, Garcia BA Journal of proteome research 25167464 J Proteome Res 2014 Oct 3 https://www.ncbi.nlm.nih.gov/pubmed/25167464
Characterization of BRD4 during mammalian postmeiotic sperm development. Bryant JM, Donahue G, Wang X, Meyer-Ficca M, Luense LJ, Weller AH, Bartolomei MS, Blobel GA, Meyer RG, Garcia BA, Berger SL Molecular and cellular biology 25691659 Mol Cell Biol 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25691659
Mass spectrometric analysis of histone proteoforms. Yuan ZF, Arnaudo AM, Garcia BA Annual review of analytical chemistry (Palo Alto, Calif.) 24896311 Annu Rev Anal Chem (Palo Alto Calif) 2014 https://www.ncbi.nlm.nih.gov/pubmed/24896311
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF Nature 22722849 Nature 2012 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/22722849
Global secretome analysis identifies novel mediators of bone metastasis. Blanco MA, LeRoy G, Khan Z, Alečković M, Zee BM, Garcia BA, Kang Y Cell research 22688892 Cell Res 2012 Sep https://www.ncbi.nlm.nih.gov/pubmed/22688892
Discovery of lysine post-translational modifications through mass spectrometric detection. Zee BM, Garcia BA Essays in biochemistry 22708569 Essays Biochem 2012 https://www.ncbi.nlm.nih.gov/pubmed/22708569
EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra. Yuan ZF, Lin S, Molden RC, Cao XJ, Bhanu NV, Wang X, Sidoli S, Liu S, Garcia BA Molecular & cellular proteomics : MCP 25805797 Mol Cell Proteomics 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25805797
Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Lu C, Jain SU, Hoelper D, Bechet D, Molden RC, Ran L, Murphy D, Venneti S, Hameed M, Pawel BR, Wunder JS, Dickson BC, Lundgren SM, Jani KS, De Jay N, Papillon-Cavanagh S, Andrulis IL, Sawyer SL, Grynspan D, Turcotte RE, Nadaf J, Fahiminiyah S, Muir TW, Majewski J, Thompson CB, Chi P, Garcia BA, Allis CD, Jabado N, Lewis PW Science (New York, N.Y.) 27174990 Science 2016 May 13 https://www.ncbi.nlm.nih.gov/pubmed/27174990
Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis. Sidoli S, Yuan ZF, Lin S, Karch K, Wang X, Bhanu N, Arnaudo AM, Britton LM, Cao XJ, Gonzales-Cope M, Han Y, Liu S, Molden RC, Wein S, Afjehi-Sadat L, Garcia BA Proteomics 25641854 Proteomics 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25641854
Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. Kang S, Tsai LT, Zhou Y, Evertts A, Xu S, Griffin MJ, Issner R, Whitton HJ, Garcia BA, Epstein CB, Mikkelsen TS, Rosen ED Nature cell biology 25503565 Nat Cell Biol 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25503565
Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry. Lin S, Wein S, Gonzales-Cope M, Otte GL, Yuan ZF, Afjehi-Sadat L, Maile T, Berger SL, Rush J, Lill JR, Arnott D, Garcia BA Molecular & cellular proteomics : MCP 25000943 Mol Cell Proteomics 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25000943
Revealing histone variant induced changes via quantitative proteomics. Arnaudo AM, Molden RC, Garcia BA Critical reviews in biochemistry and molecular biology 21526979 Crit Rev Biochem Mol Biol 2011 Aug https://www.ncbi.nlm.nih.gov/pubmed/21526979
Examining histone posttranslational modification patterns by high-resolution mass spectrometry. Lin S, Garcia BA Methods in enzymology 22910200 Methods Enzymol 2012 https://www.ncbi.nlm.nih.gov/pubmed/22910200
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Binda O, Sevilla A, LeRoy G, Lemischka IR, Garcia BA, Richard S Epigenetics 23324626 Epigenetics 2013 Feb https://www.ncbi.nlm.nih.gov/pubmed/23324626
Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton LM, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI Nature structural & molecular biology 23295261 Nat Struct Mol Biol 2013 Feb https://www.ncbi.nlm.nih.gov/pubmed/23295261
Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells. Gonzales-Cope M, Sidoli S, Bhanu NV, Won KJ, Garcia BA BMC genomics 26847871 BMC Genomics 2016 Feb 4 https://www.ncbi.nlm.nih.gov/pubmed/26847871
Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Van Aller GS, Reynoird N, Barbash O, Huddleston M, Liu S, Zmoos AF, McDevitt P, Sinnamon R, Le B, Mas G, Annan R, Sage J, Garcia BA, Tummino PJ, Gozani O, Kruger RG Epigenetics 22419068 Epigenetics 2012 Apr https://www.ncbi.nlm.nih.gov/pubmed/22419068
Combining genomic and proteomic approaches for epigenetics research. Han Y, Garcia BA Epigenomics 23895656 Epigenomics 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23895656
Proteomic characterization of novel histone post-translational modifications. Arnaudo AM, Garcia BA Epigenetics & chromatin 23916056 Epigenetics Chromatin 2013 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/23916056
H4K20 methylation regulates quiescence and chromatin compaction. Evertts AG, Manning AL, Wang X, Dyson NJ, Garcia BA, Coller HA Molecular biology of the cell 23924899 Mol Biol Cell 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/23924899
Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies. Rothbart SB, Lin S, Britton LM, Krajewski K, Keogh MC, Garcia BA, Strahl BD Scientific reports 22761995 Sci Rep 2012 https://www.ncbi.nlm.nih.gov/pubmed/22761995
Origins and formation of histone methylation across the human cell cycle. Zee BM, Britton LM, Wolle D, Haberman DM, Garcia BA Molecular and cellular biology 22547680 Mol Cell Biol 2012 Jul https://www.ncbi.nlm.nih.gov/pubmed/22547680
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Gaspar-Maia A, Qadeer ZA, Hasson D, Ratnakumar K, Leu NA, Leroy G, Liu S, Costanzi C, Valle-Garcia D, Schaniel C, Lemischka I, Garcia B, Pehrson JR, Bernstein E Nature communications 23463008 Nat Commun 2013 https://www.ncbi.nlm.nih.gov/pubmed/23463008
An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions. Sevilla A, Papatsenko D, Mazloom AR, Xu H, Vasileva A, Unwin RD, LeRoy G, Chen EY, Garrett-Bakelman FE, Lee DF, Trinite B, Webb RL, Wang Z, Su J, Gingold J, Melnick A, Garcia BA, Whetton AD, MacArthur BD, Ma'ayan A, Lemischka IR Frontiers in cell and developmental biology 33816475 Front Cell Dev Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33816475
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Lewis PW, Müller MM, Koletsky MS, Cordero F, Lin S, Banaszynski LA, Garcia BA, Muir TW, Becher OJ, Allis CD Science (New York, N.Y.) 23539183 Science 2013 May 17 https://www.ncbi.nlm.nih.gov/pubmed/23539183
Quantitative dynamics of the link between cellular metabolism and histone acetylation. Evertts AG, Zee BM, Dimaggio PA, Gonzales-Cope M, Coller HA, Garcia BA The Journal of biological chemistry 23482559 J Biol Chem 2013 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/23482559
Initial characterization of histone H3 serine 10 O-acetylation. Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA Epigenetics 23949383 Epigenetics 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/23949383
Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. Wu Y, DiMaggio PA Jr, Perlman DH, Zakian VA, Garcia BA Journal of proteome research 23181431 J Proteome Res 2013 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/23181431
Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins. LeRoy G, Chepelev I, DiMaggio PA, Blanco MA, Zee BM, Zhao K, Garcia BA Genome biology 22897906 Genome Biol 2012 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/22897906
De novo peptide design and experimental validation of histone methyltransferase inhibitors. Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, Giannis A, Trojer P, Garcia BA, Floudas CA PloS one 24587223 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/24587223
Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection. O'Connor CM, DiMaggio PA Jr, Shenk T, Garcia BA Molecular & cellular proteomics : MCP 24987098 Mol Cell Proteomics 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/24987098
Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, Won KJ, Chodosh LA, Garcia BA, Stanger BZ, Feldman MD, Blair IA, Wellen KE Cell metabolism 24998913 Cell Metab 2014 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/24998913
H3R42me2a is a histone modification with positive transcriptional effects. Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD Proceedings of the National Academy of Sciences of the United States of America 23980157 Proc Natl Acad Sci U S A 2013 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/23980157
Neutron-encoded mass signatures for quantitative top-down proteomics. Rhoads TW, Rose CM, Bailey DJ, Riley NM, Molden RC, Nestler AJ, Merrill AE, Smith LM, Hebert AS, Westphall MS, Pagliarini DJ, Garcia BA, Coon JJ Analytical chemistry 24475910 Anal Chem 2014 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/24475910
Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses. Green EM, Mas G, Young NL, Garcia BA, Gozani O Nature structural & molecular biology 22343720 Nat Struct Mol Biol 2012 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/22343720
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Kuo AJ, Cheung P, Chen K, Zee BM, Kioi M, Lauring J, Xi Y, Park BH, Shi X, Garcia BA, Li W, Gozani O Molecular cell 22099308 Mol Cell 2011 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/22099308
Complete Workflow for Analysis of Histone Post-translational Modifications Using Bottom-up Mass Spectrometry: From Histone Extraction to Data Analysis. Sidoli S, Bhanu NV, Karch KR, Wang X, Garcia BA Journal of visualized experiments : JoVE 27286567 J Vis Exp 2016 May 17 https://www.ncbi.nlm.nih.gov/pubmed/27286567
SnapShot: histone modifications. Huang H, Sabari BR, Garcia BA, Allis CD, Zhao Y Cell 25303536 Cell 2014 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/25303536
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia. Xu B, On DM, Ma A, Parton T, Konze KD, Pattenden SG, Allison DF, Cai L, Rockowitz S, Liu S, Liu Y, Li F, Vedadi M, Frye SV, Garcia BA, Zheng D, Jin J, Wang GG Blood 25395428 Blood 2015 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/25395428
Quantitative proteomic approaches to studying histone modifications. Zee BM, Young NL, Garcia BA Current chemical genomics 21966350 Curr Chem Genomics 2011 https://www.ncbi.nlm.nih.gov/pubmed/21966350
Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications. Molden RC, Bhanu NV, LeRoy G, Arnaudo AM, Garcia BA Epigenetics & chromatin 25922622 Epigenetics Chromatin 2015 https://www.ncbi.nlm.nih.gov/pubmed/25922622
Bottom-up and middle-down proteomics have comparable accuracies in defining histone post-translational modification relative abundance and stoichiometry. Sidoli S, Lin S, Karch KR, Garcia BA Analytical chemistry 25719549 Anal Chem 2015 Mar 17 https://www.ncbi.nlm.nih.gov/pubmed/25719549
Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications. Vasudevan D, Hickok JR, Bovee RC, Pham V, Mantell LL, Bahroos N, Kanabar P, Cao XJ, Maienschein-Cline M, Garcia BA, Thomas DD Cancer research 26542213 Cancer Res 2015 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/26542213
Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2. Garrigues JM, Sidoli S, Garcia BA, Strome S Genome research 25467431 Genome Res 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25467431
Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain. Menni C, Jackson MA, Pallister T, Steves CJ, Spector TD, Valdes AM International journal of obesity (2005) 28286339 Int J Obes (Lond) 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28286339
Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice. Ji Y, Sun S, Goodrich JK, Kim H, Poole AC, Duhamel GE, Ley RE, Qi L Cell reports 24953658 Cell Rep 2014 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/24953658
Signatures of early frailty in the gut microbiota. Jackson MA, Jeffery IB, Beaumont M, Bell JT, Clark AG, Ley RE, O'Toole PW, Spector TD, Steves CJ Genome medicine 26822992 Genome Med 2016 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/26822992
Host remodeling of the gut microbiome and metabolic changes during pregnancy. Koren O, Goodrich JK, Cullender TC, Spor A, Laitinen K, Bäckhed HK, Gonzalez A, Werner JJ, Angenent LT, Knight R, Bäckhed F, Isolauri E, Salminen S, Ley RE Cell 22863002 Cell 2012 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/22863002
Innate and adaptive immunity interact to quench microbiome flagellar motility in the gut. Cullender TC, Chassaing B, Janzon A, Kumar K, Muller CE, Werner JJ, Angenent LT, Bell ME, Hay AG, Peterson DA, Walter J, Vijay-Kumar M, Gewirtz AT, Ley RE Cell host & microbe 24237702 Cell Host Microbe 2013 Nov 13 https://www.ncbi.nlm.nih.gov/pubmed/24237702
Human genetics shape the gut microbiome. Goodrich JK, Waters JL, Poole AC, Sutter JL, Koren O, Blekhman R, Beaumont M, Van Treuren W, Knight R, Bell JT, Spector TD, Clark AG, Ley RE Cell 25417156 Cell 2014 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/25417156
Resilience of small intestinal beneficial bacteria to the toxicity of soybean oil fatty acids. Di Rienzi SC, Jacobson J, Kennedy EA, Bell ME, Shi Q, Waters JL, Lawrence P, Brenna JT, Britton RA, Walter J, Ley RE eLife 29580380 Elife 2018 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/29580380
Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women. Menni C, Zierer J, Pallister T, Jackson MA, Long T, Mohney RP, Steves CJ, Spector TD, Valdes AM Scientific reports 28894110 Sci Rep 2017 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/28894110
A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units. Jackson MA, Bell JT, Spector TD, Steves CJ PeerJ 27635321 PeerJ 2016 https://www.ncbi.nlm.nih.gov/pubmed/27635321
Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice. Carvalho FA, Koren O, Goodrich JK, Johansson ME, Nalbantoglu I, Aitken JD, Su Y, Chassaing B, Walters WA, González A, Clemente JC, Cullender TC, Barnich N, Darfeuille-Michaud A, Vijay-Kumar M, Knight R, Ley RE, Gewirtz AT Cell host & microbe 22863420 Cell Host Microbe 2012 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/22863420
Virome Diversity Correlates with Intestinal Microbiome Diversity in Adult Monozygotic Twins. Moreno-Gallego JL, Chou SP, Di Rienzi SC, Goodrich JK, Spector TD, Bell JT, Youngblut ND, Hewson I, Reyes A, Ley RE Cell host & microbe 30763537 Cell Host Microbe 2019 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/30763537
Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis. Carvalho FA, Nalbantoglu I, Ortega-Fernandez S, Aitken JD, Su Y, Koren O, Walters WA, Knight R, Ley RE, Vijay-Kumar M, Gewirtz AT Gut 21646247 Gut 2012 Mar https://www.ncbi.nlm.nih.gov/pubmed/21646247
An Investigation Into Physical Frailty as a Link Between the Gut Microbiome and Cognitive Health. Verdi S, Jackson MA, Beaumont M, Bowyer RCE, Bell JT, Spector TD, Steves CJ Frontiers in aging neuroscience 30564113 Front Aging Neurosci 2018 https://www.ncbi.nlm.nih.gov/pubmed/30564113
Red Wine Consumption Associated With Increased Gut Microbiota α-Diversity in 3 Independent Cohorts. Le Roy CI, Wells PM, Si J, Raes J, Bell JT, Spector TD Gastroenterology 31472153 Gastroenterology 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31472153
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Inhibitors of reactive oxygen species accumulation delay and/or reduce the lethality of several antistaphylococcal agents. Liu Y, Liu X, Qu Y, Wang X, Li L, Zhao X Antimicrobial agents and chemotherapy 22948880 Antimicrob Agents Chemother 2012 Nov https://www.ncbi.nlm.nih.gov/pubmed/22948880
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Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia. Klossowski S, Miao H, Kempinska K, Wu T, Purohit T, Kim E, Linhares BM, Chen D, Jih G, Perkey E, Huang H, He M, Wen B, Wang Y, Yu K, Lee SC, Danet-Desnoyers G, Trotman W, Kandarpa M, Cotton A, Abdel-Wahab O, Lei H, Dou Y, Guzman M, Peterson L, Gruber T, Choi S, Sun D, Ren P, Li LS, Liu Y, Burrows F, Maillard I, Cierpicki T, Grembecka J The Journal of clinical investigation 31855575 J Clin Invest 2020 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/31855575
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Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy. Taldone T, Gomes-DaGama EM, Zong H, Sen S, Alpaugh ML, Zatorska D, Alonso-Sabadell R, Guzman ML, Chiosis G Bioorganic & medicinal chemistry letters 21802945 Bioorg Med Chem Lett 2011 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/21802945
Acute myelogenous leukemia stem cells: from Bench to Bedside. Felipe Rico J, Hassane DC, Guzman ML Cancer letters 22713929 Cancer Lett 2013 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/22713929
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Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin. Madadi NR, Zong H, Ketkar A, Zheng C, Penthala NR, Janganati V, Bommagani S, Eoff RL, Guzman ML, Crooks PA MedChemComm 26257861 Medchemcomm 2015 May 1 https://www.ncbi.nlm.nih.gov/pubmed/26257861
Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. Illendula A, Gilmour J, Grembecka J, Tirumala VSS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, Mishra L, Adli M, Castilla LH, Rajewski RA, Janes KA, Guzman ML, Bonifer C, Bushweller JH EBioMedicine 27428424 EBioMedicine 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27428424
Is minimal residual disease monitoring clinically relevant in adults with acute myelogenous leukemia? Carlson KS, Guzman ML Current hematologic malignancy reports 23563936 Curr Hematol Malig Rep 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23563936
A phase I study using bortezomib with weekly idarubicin for treatment of elderly patients with acute myeloid leukemia. Howard DS, Liesveld J, Phillips GL 2nd, Hayslip J, Weiss H, Jordan CT, Guzman ML Leukemia research 24075534 Leuk Res 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/24075534
Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells. Bystrom LM, Bezerra DP, Hsu HT, Zong H, Lara-Martínez LA, De Leon JP, Emmanuel M, Méry D, Gardenghi S, Hassane D, Neto CC, Cunningham-Rundles S, Becker MW, Rivella S, Guzman ML Blood advances 31698457 Blood Adv 2019 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/31698457
Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture. Nasim S, Guzman ML, Jordan CT, Crooks PA Bioorganic & medicinal chemistry letters 21757349 Bioorg Med Chem Lett 2011 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/21757349
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90. Moulick K, Ahn JH, Zong H, Rodina A, Cerchietti L, Gomes DaGama EM, Caldas-Lopes E, Beebe K, Perna F, Hatzi K, Vu LP, Zhao X, Zatorska D, Taldone T, Smith-Jones P, Alpaugh M, Gross SS, Pillarsetty N, Ku T, Lewis JS, Larson SM, Levine R, Erdjument-Bromage H, Guzman ML, Nimer SD, Melnick A, Neckers L, Chiosis G Nature chemical biology 21946277 Nat Chem Biol 2011 Sep 25 https://www.ncbi.nlm.nih.gov/pubmed/21946277
Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents. Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA European journal of medicinal chemistry 25557492 Eur J Med Chem 2015 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/25557492
Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, Sen S, Zhou Y, Boulton A, Kuntimaddi A, Gao Y, Rajewski RA, Guzman ML, Castilla LH, Bushweller JH Science (New York, N.Y.) 25678665 Science 2015 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/25678665
Dehydroleucodine, a Sesquiterpene Lactone from Gynoxys verrucosa, Demonstrates Cytotoxic Activity against Human Leukemia Cells. Ordóñez PE, Sharma KK, Bystrom LM, Alas MA, Enriquez RG, Malagón O, Jones DE, Guzman ML, Compadre CM Journal of natural products 27057812 J Nat Prod 2016 Apr 22 https://www.ncbi.nlm.nih.gov/pubmed/27057812
Three-dimensional carbon nanotube scaffolds for long-term maintenance and expansion of human mesenchymal stem cells. Lalwani G, D'agati M, Gopalan A, Patel SC, Talukdar Y, Sitharaman B Journal of biomedical materials research. Part A 28295953 J Biomed Mater Res A 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28295953
Structural disruption increases toxicity of graphene nanoribbons. Mullick Chowdhury S, Dasgupta S, McElroy AE, Sitharaman B Journal of applied toxicology : JAT 25224919 J Appl Toxicol 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25224919
Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme. Chowdhury SM, Surhland C, Sanchez Z, Chaudhary P, Suresh Kumar MA, Lee S, Peña LA, Waring M, Sitharaman B, Naidu M Nanomedicine : nanotechnology, biology, and medicine 25131339 Nanomedicine 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25131339
The effects of graphene nanostructures on mesenchymal stem cells. Talukdar Y, Rashkow J, Lalwani G, Kanakia S, Sitharaman B Biomaterials 24674462 Biomaterials 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24674462
Quantification of single-cell nanoparticle concentrations and the distribution of these concentrations in cell population. Rashkow JT, Patel SC, Tappero R, Sitharaman B Journal of the Royal Society, Interface 24554576 J R Soc Interface 2014 May 6 https://www.ncbi.nlm.nih.gov/pubmed/24554576
Two-dimensional nanostructure-reinforced biodegradable polymeric nanocomposites for bone tissue engineering. Lalwani G, Henslee AM, Farshid B, Lin L, Kasper FK, Qin YX, Mikos AG, Sitharaman B Biomacromolecules 23405887 Biomacromolecules 2013 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/23405887
Multiscale photoacoustic microscopy of single-walled carbon nanotube-incorporated tissue engineering scaffolds. Cai X, Paratala BS, Hu S, Sitharaman B, Wang LV Tissue engineering. Part C, Methods 22082018 Tissue Eng Part C Methods 2012 Apr https://www.ncbi.nlm.nih.gov/pubmed/22082018
A novel nanoparticle-enhanced photoacoustic stimulus for bone tissue engineering. Sitharaman B, Avti PK, Schaefer K, Talukdar Y, Longtin JP Tissue engineering. Part A 21395444 Tissue Eng Part A 2011 Jul https://www.ncbi.nlm.nih.gov/pubmed/21395444
Graphene-based platforms for cancer therapeutics. Patel SC, Lee S, Lalwani G, Suhrland C, Chowdhury SM, Sitharaman B Therapeutic delivery 26769305 Ther Deliv 2016 https://www.ncbi.nlm.nih.gov/pubmed/26769305
Fabrication and cytocompatibility of in situ crosslinked carbon nanomaterial films. Patel SC, Lalwani G, Grover K, Qin YX, Sitharaman B Scientific reports 26018775 Sci Rep 2015 May 28 https://www.ncbi.nlm.nih.gov/pubmed/26018775
In Vitro Bioactivity of One- and Two-Dimensional Nanoparticle-Incorporated Bone Tissue Engineering Scaffolds. Rashkow JT, Lalwani G, Sitharaman B Tissue engineering. Part A 28762866 Tissue Eng Part A 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/28762866
In vitro cytocompatibility of one-dimensional and two-dimensional nanostructure-reinforced biodegradable polymeric nanocomposites. Farshid B, Lalwani G, Sitharaman B Journal of biomedical materials research. Part A 25367032 J Biomed Mater Res A 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/25367032
Toxicology of graphene-based nanomaterials. Lalwani G, D'Agati M, Khan AM, Sitharaman B Advanced drug delivery reviews 27154267 Adv Drug Deliv Rev 2016 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/27154267
Delivery of long chain C(16) and C(24) ceramide in HeLa cells using oxidized graphene nanoribbons. Suhrland C, Truman JP, Obeid LM, Sitharaman B Journal of biomedical materials research. Part B, Applied biomaterials 31444959 J Biomed Mater Res B Appl Biomater 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/31444959
Enzymatic Degradation of Oxidized and Reduced Graphene Nanoribbons by Lignin Peroxidase. Lalwani G, Xing W, Sitharaman B Journal of materials chemistry. B 25215188 J Mater Chem B 2014 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/25215188
Graphene-based contrast agents for photoacoustic and thermoacoustic tomography. Lalwani G, Cai X, Nie L, Wang LV, Sitharaman B Photoacoustics 24490141 Photoacoustics 2013 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/24490141
Graphene nanoribbons elicit cell specific uptake and delivery via activation of epidermal growth factor receptor enhanced by human papillomavirus E5 protein. Mullick Chowdhury S, Manepalli P, Sitharaman B Acta biomaterialia 24980059 Acta Biomater 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/24980059
Synthesis, Characterization, In Vitro Phantom Imaging, and Cytotoxicity of A Novel Graphene-Based Multimodal Magnetic Resonance Imaging - X-Ray Computed Tomography Contrast Agent. Lalwani G, Sundararaj JL, Schaefer K, Button T, Sitharaman B Journal of materials chemistry. B 24999431 J Mater Chem B 2014 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/24999431
Physicochemical characterization, and relaxometry studies of micro-graphite oxide, graphene nanoplatelets, and nanoribbons. Paratala BS, Jacobson BD, Kanakia S, Francis LD, Sitharaman B PloS one 22685555 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/22685555
Porous three-dimensional carbon nanotube scaffolds for tissue engineering. Lalwani G, Gopalan A, D'Agati M, Sankaran JS, Judex S, Qin YX, Sitharaman B Journal of biomedical materials research. Part A 25788440 J Biomed Mater Res A 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/25788440
Interactions of 1D- and 2D-layered inorganic nanoparticles with fibroblasts and human mesenchymal stem cells. Rashkow JT, Talukdar Y, Lalwani G, Sitharaman B Nanomedicine (London, England) 26080694 Nanomedicine (Lond) 2015 https://www.ncbi.nlm.nih.gov/pubmed/26080694
Cytotoxicity, cytocompatibility, cell-labeling efficiency, and in vitro cellular magnetic resonance imaging of gadolinium-catalyzed single-walled carbon nanotubes. Avti PK, Caparelli ED, Sitharaman B Journal of biomedical materials research. Part A 23686792 J Biomed Mater Res A 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/23686792
Boron nitride nanotubes and nanoplatelets as reinforcing agents of polymeric matrices for bone tissue engineering. Farshid B, Lalwani G, Shir Mohammadi M, Simonsen J, Sitharaman B Journal of biomedical materials research. Part B, Applied biomaterials 26526153 J Biomed Mater Res B Appl Biomater 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/26526153
Nanofilm generated non-pharmacological anabolic bone stimulus. Talukdar Y, Rashkow JT, Patel S, Lalwani G, Bastidas J, Khan S, Sitharaman B Journal of biomedical materials research. Part A 31581364 J Biomed Mater Res A 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31581364
Detection, mapping, and quantification of single walled carbon nanotubes in histological specimens with photoacoustic microscopy. Avti PK, Hu S, Favazza C, Mikos AG, Jansen JA, Shroyer KR, Wang LV, Sitharaman B PloS one 22496892 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/22496892
Multimodal ultrasound-photoacoustic imaging of tissue engineering scaffolds and blood oxygen saturation in and around the scaffolds. Talukdar Y, Avti P, Sun J, Sitharaman B Tissue engineering. Part C, Methods 24107069 Tissue Eng Part C Methods 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24107069
Fabrication and Characterization of Three-Dimensional Macroscopic All-Carbon Scaffolds. Lalwani G, Kwaczala AT, Kanakia S, Patel SC, Judex S, Sitharaman B Carbon 23436939 Carbon N Y 2013 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/23436939
The magnetic, relaxometric, and optical properties of gadolinium-catalyzed single walled carbon nanotubes. Sitharaman B, Jacobson BD, Wadghiri YZ, Bryant H, Frank J Journal of applied physics 23653487 J Appl Phys 2013 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/23653487
Tungsten disulfide nanotubes reinforced biodegradable polymers for bone tissue engineering. Lalwani G, Henslee AM, Farshid B, Parmar P, Lin L, Qin YX, Kasper FK, Mikos AG, Sitharaman B Acta biomaterialia 23727293 Acta Biomater 2013 Sep https://www.ncbi.nlm.nih.gov/pubmed/23727293
Interaction of graphene nanoribbons with components of the blood vascular system. Chowdhury SM, Fang J, Sitharaman B Future science OA 26925250 Future Sci OA 2015 https://www.ncbi.nlm.nih.gov/pubmed/26925250
Toward single-walled carbon nanotube-gadolinium complex as advanced MRI contrast agents: pharmacodynamics and global genomic response in small animals. Avti PK, Talukdar Y, Sirotkin MV, Shroyer KR, Sitharaman B Journal of biomedical materials research. Part B, Applied biomaterials 23559429 J Biomed Mater Res B Appl Biomater 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23559429
Cell specific cytotoxicity and uptake of graphene nanoribbons. Mullick Chowdhury S, Lalwani G, Zhang K, Yang JY, Neville K, Sitharaman B Biomaterials 23072942 Biomaterials 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/23072942
Vasoactive effects of stable aqueous suspensions of single walled carbon nanotubes in hamsters and mice. Frame MD, Dewar AM, Mullick Chowdhury S, Sitharaman B Nanotoxicology 23992463 Nanotoxicology 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/23992463
Determination of binding kinetics using whispering gallery mode microcavities. Soteropulos CE, Hunt HK, Armani AM Applied physics letters 21990943 Appl Phys Lett 2011 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/21990943
Label free detection of 5'hydroxymethylcytosine within CpG islands using optical sensors. Hawk RM, Armani AM Biosensors & bioelectronics 25461158 Biosens Bioelectron 2015 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/25461158
Temperature sensor based on a hybrid ITO-silica resonant cavity. Socorro AB, Soltani S, Del Villar I, Corres JM, Armani AM Optics express 25836065 Opt Express 2015 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/25836065
Attaching biological probes to silica optical biosensors using silane coupling agents. Soteropulos CE, Hunt HK Journal of visualized experiments : JoVE 22588224 J Vis Exp 2012 May 1 https://www.ncbi.nlm.nih.gov/pubmed/22588224
Selective patterning of Si-based biosensor surfaces using isotropic silicon etchants. Biggs BW, Hunt HK, Armani AM Journal of colloid and interface science 22196345 J Colloid Interface Sci 2012 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/22196345
Monitoring DNA hybridization using optical microcavities. Hawk RM, Chistiakova MV, Armani AM Optics letters 24322107 Opt Lett 2013 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/24322107
Titanium-enhanced Raman microcavity laser. Deka N, Maker AJ, Armani AM Optics letters 24690786 Opt Lett 2014 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/24690786
Nanowatt threshold, alumina sensitized neodymium laser integrated on silicon. Maker AJ, Armani AM Optics express 24216946 Opt Express 2013 Nov 4 https://www.ncbi.nlm.nih.gov/pubmed/24216946
Recycling microcavity optical biosensors. Hunt HK, Armani AM Optics letters 21478993 Opt Lett 2011 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/21478993
Real-time detection of lipid bilayer assembly and detergent-initiated solubilization using optical cavities. Sun V, Armani AM Applied physics letters 25759510 Appl Phys Lett 2015 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/25759510
Classifying human brain tumors by lipid imaging with mass spectrometry. Eberlin LS, Norton I, Dill AL, Golby AJ, Ligon KL, Santagata S, Cooks RG, Agar NY Cancer research 22139378 Cancer Res 2012 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/22139378
Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors. Eberlin LS, Norton I, Orringer D, Dunn IF, Liu X, Ide JL, Jarmusch AK, Ligon KL, Jolesz FA, Golby AJ, Santagata S, Agar NY, Cooks RG Proceedings of the National Academy of Sciences of the United States of America 23300285 Proc Natl Acad Sci U S A 2013 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/23300285
The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma. Pokorny JL, Calligaris D, Gupta SK, Iyekegbe DO Jr, Mueller D, Bakken KK, Carlson BL, Schroeder MA, Evans DL, Lou Z, Decker PA, Eckel-Passow JE, Pucci V, Ma B, Shumway SD, Elmquist WF, Agar NY, Sarkaria JN Clinical cancer research : an official journal of the American Association for Cancer Research 25609063 Clin Cancer Res 2015 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/25609063
Reconstruction and Feature Selection for Desorption Electrospray Ionization Mass Spectroscopy Imagery. Gao Y, Zhu L, Norton I, Agar NY, Tannenbaum A Proceedings of SPIE--the International Society for Optical Engineering 25302009 Proc SPIE Int Soc Opt Eng 2014 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/25302009
Molecular typing of Meningiomas by Desorption Electrospray Ionization Mass Spectrometry Imaging for Surgical Decision-Making. Calligaris D, Feldman DR, Norton I, Brastianos PK, Dunn IF, Santagata S, Agar NY International journal of mass spectrometry 25844057 Int J Mass Spectrom 2015 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/25844057
First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development. Jonas O, Calligaris D, Methuku KR, Poe MM, Francois JP, Tranghese F, Changelian A, Sieghart W, Ernst M, Krummel DA, Cook JM, Pomeroy SL, Cima M, Agar NY, Langer R, Sengupta S Journal of biomedical nanotechnology 27319222 J Biomed Nanotechnol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27319222
Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC-ESI-MS-MS. Kertesz V, Calligaris D, Feldman DR, Changelian A, Laws ER, Santagata S, Agar NY, Van Berkel GJ Analytical and bioanalytical chemistry 26084546 Anal Bioanal Chem 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26084546
A statistical modeling approach for tumor-type identification in surgical neuropathology using tissue mass spectrometry imaging. Gholami B, Norton I, Eberlin LS, Agar NY IEEE journal of biomedical and health informatics 24592474 IEEE J Biomed Health Inform 2013 May https://www.ncbi.nlm.nih.gov/pubmed/24592474
Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery. Santagata S, Eberlin LS, Norton I, Calligaris D, Feldman DR, Ide JL, Liu X, Wiley JS, Vestal ML, Ramkissoon SH, Orringer DA, Gill KK, Dunn IF, Dias-Santagata D, Ligon KL, Jolesz FA, Golby AJ, Cooks RG, Agar NY Proceedings of the National Academy of Sciences of the United States of America 24982150 Proc Natl Acad Sci U S A 2014 Jul 29 https://www.ncbi.nlm.nih.gov/pubmed/24982150
Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System. Parrish KE, Cen L, Murray J, Calligaris D, Kizilbash S, Mittapalli RK, Carlson BL, Schroeder MA, Sludden J, Boddy AV, Agar NY, Curtin NJ, Elmquist WF, Sarkaria JN Molecular cancer therapeutics 26438157 Mol Cancer Ther 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26438157
Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis. Calligaris D, Caragacianu D, Liu X, Norton I, Thompson CJ, Richardson AL, Golshan M, Easterling ML, Santagata S, Dillon DA, Jolesz FA, Agar NY Proceedings of the National Academy of Sciences of the United States of America 25246570 Proc Natl Acad Sci U S A 2014 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/25246570
A compressive sensing approach for glioma margin delineation using mass spectrometry. Gholami B, Agar NY, Jolesz FA, Haddad WM, Tannenbaum AR Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 22255629 Annu Int Conf IEEE Eng Med Biol Soc 2011 https://www.ncbi.nlm.nih.gov/pubmed/22255629
Desorption electrospray ionization then MALDI mass spectrometry imaging of lipid and protein distributions in single tissue sections. Eberlin LS, Liu X, Ferreira CR, Santagata S, Agar NY, Cooks RG Analytical chemistry 21975048 Anal Chem 2011 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/21975048
Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging. Liu X, Ide JL, Norton I, Marchionni MA, Ebling MC, Wang LY, Davis E, Sauvageot CM, Kesari S, Kellersberger KA, Easterling ML, Santagata S, Stuart DD, Alberta J, Agar JN, Stiles CD, Agar NY Scientific reports 24091529 Sci Rep 2013 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/24091529
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Genomics of Loa loa, a Wolbachia-free filarial parasite of humans. Desjardins CA, Cerqueira GC, Goldberg JM, Dunning Hotopp JC, Haas BJ, Zucker J, Ribeiro JM, Saif S, Levin JZ, Fan L, Zeng Q, Russ C, Wortman JR, Fink DL, Birren BW, Nutman TB Nature genetics 23525074 Nat Genet 2013 May https://www.ncbi.nlm.nih.gov/pubmed/23525074
Targeted Enrichment and Sequencing of Recent Endosymbiont-Host Lateral Gene Transfers. Dunning Hotopp JC, Slatko BE, Foster JM Scientific reports 28405008 Sci Rep 2017 Apr 12 https://www.ncbi.nlm.nih.gov/pubmed/28405008
Extensive duplication of the Wolbachia DNA in chromosome four of Drosophila ananassae. Klasson L, Kumar N, Bromley R, Sieber K, Flowers M, Ott SH, Tallon LJ, Andersson SG, Dunning Hotopp JC BMC genomics 25496002 BMC Genomics 2014 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/25496002
Mobile elements and viral integrations prompt considerations for bacterial DNA integration as a novel carcinogen. Robinson KM, Dunning Hotopp JC Cancer letters 24956175 Cancer Lett 2014 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/24956175
Extensively duplicated and transcriptionally active recent lateral gene transfer from a bacterial Wolbachia endosymbiont to its host filarial nematode Brugia malayi. Ioannidis P, Johnston KL, Riley DR, Kumar N, White JR, Olarte KT, Ott S, Tallon LJ, Foster JM, Taylor MJ, Dunning Hotopp JC BMC genomics 24053607 BMC Genomics 2013 Sep 22 https://www.ncbi.nlm.nih.gov/pubmed/24053607
Modeling the integration of bacterial rRNA fragments into the human cancer genome. Sieber KB, Gajer P, Dunning Hotopp JC BMC bioinformatics 27001685 BMC Bioinformatics 2016 Mar 21 https://www.ncbi.nlm.nih.gov/pubmed/27001685
Lateral gene transfer between prokaryotes and eukaryotes. Sieber KB, Bromley RE, Dunning Hotopp JC Experimental cell research 28189637 Exp Cell Res 2017 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/28189637
Efficient Enrichment of Bacterial mRNA from Host-Bacteria Total RNA Samples. Kumar N, Lin M, Zhao X, Ott S, Santana-Cruz I, Daugherty S, Rikihisa Y, Sadzewicz L, Tallon LJ, Fraser CM, Dunning Hotopp JC Scientific reports 27713560 Sci Rep 2016 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/27713560
Biology wars: the eukaryotes strike back. Dunning Hotopp JC, Estes AM Cell host & microbe 25498339 Cell Host Microbe 2014 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/25498339
A review of bacteria-animal lateral gene transfer may inform our understanding of diseases like cancer. Robinson KM, Sieber KB, Dunning Hotopp JC PLoS genetics 24146634 PLoS Genet 2013 https://www.ncbi.nlm.nih.gov/pubmed/24146634
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Distinguishing potential bacteria-tumor associations from contamination in a secondary data analysis of public cancer genome sequence data. Robinson KM, Crabtree J, Mattick JS, Anderson KE, Dunning Hotopp JC Microbiome 28118849 Microbiome 2017 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/28118849
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Single molecule sequencing and genome assembly of a clinical specimen of Loa loa, the causative agent of loiasis. Tallon LJ, Liu X, Bennuru S, Chibucos MC, Godinez A, Ott S, Zhao X, Sadzewicz L, Fraser CM, Nutman TB, Dunning Hotopp JC BMC genomics 25217238 BMC Genomics 2014 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/25217238
The genome of Onchocerca volvulus, agent of river blindness. Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, Ribeiro JM, Rogers MB, Stanley E, Swapna LS, Tsai IJ, Unnasch TR, Voronin D, Parkinson J, Nutman TB, Ghedin E, Berriman M, Lustigman S Nature microbiology 27869790 Nat Microbiol 2016 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/27869790
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Bacterial argonaute samples the transcriptome to identify foreign DNA. Olovnikov I, Chan K, Sachidanandam R, Newman DK, Aravin AA Molecular cell 24034694 Mol Cell 2013 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/24034694
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piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells. Pezic D, Manakov SA, Sachidanandam R, Aravin AA Genes & development 24939875 Genes Dev 2014 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/24939875
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Psychiatric blood biomarkers: avoiding jumping to premature negative or positive conclusions. Niculescu AB, Levey D, Le-Niculescu H, Niculescu E, Kurian SM, Salomon D Molecular psychiatry 25582618 Mol Psychiatry 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25582618
Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs. Niculescu AB, Le-Niculescu H, Roseberry K, Wang S, Hart J, Kaur A, Robertson H, Jones T, Strasburger A, Williams A, Kurian SM, Lamb B, Shekhar A, Lahiri DK, Saykin AJ Molecular psychiatry 31792364 Mol Psychiatry 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/31792364
Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs. Le-Niculescu H, Roseberry K, Levey DF, Rogers J, Kosary K, Prabha S, Jones T, Judd S, McCormick MA, Wessel AR, Williams A, Phalen PL, Mamdani F, Sequeira A, Kurian SM, Niculescu AB Molecular psychiatry 30862937 Mol Psychiatry 2020 May https://www.ncbi.nlm.nih.gov/pubmed/30862937
Convergent functional genomics of stem cell-derived cells. Niculescu AB Translational psychiatry 24022510 Transl Psychiatry 2013 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/24022510
Discovery and validation of blood biomarkers for suicidality. Le-Niculescu H, Levey DF, Ayalew M, Palmer L, Gavrin LM, Jain N, Winiger E, Bhosrekar S, Shankar G, Radel M, Bellanger E, Duckworth H, Olesek K, Vergo J, Schweitzer R, Yard M, Ballew A, Shekhar A, Sandusky GE, Schork NJ, Kurian SM, Salomon DR, Niculescu AB 3rd Molecular psychiatry 23958961 Mol Psychiatry 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/23958961
Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Ayalew M, Le-Niculescu H, Levey DF, Jain N, Changala B, Patel SD, Winiger E, Breier A, Shekhar A, Amdur R, Koller D, Nurnberger JI, Corvin A, Geyer M, Tsuang MT, Salomon D, Schork NJ, Fanous AH, O'Donovan MC, Niculescu AB Molecular psychiatry 22584867 Mol Psychiatry 2012 Sep https://www.ncbi.nlm.nih.gov/pubmed/22584867
Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms. Le-Niculescu H, Balaraman Y, Patel SD, Ayalew M, Gupta J, Kuczenski R, Shekhar A, Schork N, Geyer MA, Niculescu AB Translational psychiatry 22832404 Transl Psychiatry 2011 May 24 https://www.ncbi.nlm.nih.gov/pubmed/22832404
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Towards understanding and predicting suicidality in women: biomarkers and clinical risk assessment. Levey DF, Niculescu EM, Le-Niculescu H, Dainton HL, Phalen PL, Ladd TB, Weber H, Belanger E, Graham DL, Khan FN, Vanipenta NP, Stage EC, Ballew A, Yard M, Gelbart T, Shekhar A, Schork NJ, Kurian SM, Sandusky GE, Salomon DR, Niculescu AB Molecular psychiatry 27046645 Mol Psychiatry 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27046645
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Genetic risk prediction and neurobiological understanding of alcoholism. Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Wodarz N, Müller-Myhsok B, Dahmen N, GESGA Consortium, Nöthen M, Sherva R, Farrer L, Smith AH, Kranzler HR, Rietschel M, Gelernter J, Niculescu AB Translational psychiatry 24844177 Transl Psychiatry 2014 May 20 https://www.ncbi.nlm.nih.gov/pubmed/24844177
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Precision medicine for suicidality: from universality to subtypes and personalization. Niculescu AB, Le-Niculescu H, Levey DF, Phalen PL, Dainton HL, Roseberry K, Niculescu EM, Niezer JO, Williams A, Graham DL, Jones TJ, Venugopal V, Ballew A, Yard M, Gelbart T, Kurian SM, Shekhar A, Schork NJ, Sandusky GE, Salomon DR Molecular psychiatry 28809398 Mol Psychiatry 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/28809398
Convergent functional genomics of psychiatric disorders. Niculescu AB American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 23728881 Am J Med Genet B Neuropsychiatr Genet 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/23728881
Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs. Niculescu AB, Le-Niculescu H, Levey DF, Roseberry K, Soe KC, Rogers J, Khan F, Jones T, Judd S, McCormick MA, Wessel AR, Williams A, Kurian SM, White FA Molecular psychiatry 30755720 Mol Psychiatry 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30755720
Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism. Le-Niculescu H, Case NJ, Hulvershorn L, Patel SD, Bowker D, Gupta J, Bell R, Edenberg HJ, Tsuang MT, Kuczenski R, Geyer MA, Rodd ZA, Niculescu AB Translational psychiatry 22832392 Transl Psychiatry 2011 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/22832392
Dissecting Suicidality Using a Combined Genomic and Clinical Approach. Niculescu AB, Le-Niculescu H Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 27909331 Neuropsychopharmacology 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27909331
The role of nanomaterials in translational medicine. Lavik E, von Recum H ACS nano 21604811 ACS Nano 2011 May 24 https://www.ncbi.nlm.nih.gov/pubmed/21604811
Short term interactions with long term consequences: modulation of chimeric vessels by neural progenitors. Williams C, Rauch MF, Michaud M, Robinson R, Xu H, Madri J, Lavik E PloS one 23300890 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/23300890
Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: the role of size for intraocular drug delivery. Robinson R, Viviano SR, Criscione JM, Williams CA, Jun L, Tsai JC, Lavik EB ACS nano 21619059 ACS Nano 2011 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/21619059
Steroid-Loaded Hemostatic Nanoparticles Combat Lung Injury after Blast Trauma. Hubbard WB, Lashof-Sullivan MM, Lavik EB, VandeVord PJ ACS macro letters 27668129 ACS Macro Lett 2015 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/27668129
Hemostatic Nanoparticles Improve Survival Following Blunt Trauma Even after 1 Week Incubation at 50 (°)C. Lashof-Sullivan M, Holland M, Groynom R, Campbell D, Shoffstall A, Lavik E ACS biomaterials science & engineering 27672679 ACS Biomater Sci Eng 2016 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/27672679
Intravenously administered nanoparticles increase survival following blast trauma. Lashof-Sullivan MM, Shoffstall E, Atkins KT, Keane N, Bir C, VandeVord P, Lavik EB Proceedings of the National Academy of Sciences of the United States of America 24982180 Proc Natl Acad Sci U S A 2014 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/24982180
Intravenous hemostats: challenges in translation to patients. Lashof-Sullivan M, Shoffstall A, Lavik E Nanoscale 24088870 Nanoscale 2013 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/24088870
A hydrogel-endothelial cell implant mimics infantile hemangioma: modulation by survivin and the Hippo pathway. Tsuneki M, Hardee S, Michaud M, Morotti R, Lavik E, Madri JA Laboratory investigation; a journal of technical methods and pathology 25961170 Lab Invest 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/25961170
Engineering Intravenously Administered Nanoparticles to Reduce Infusion Reaction and Stop Bleeding in a Large Animal Model of Trauma. Onwukwe C, Maisha N, Holland M, Varley M, Groynom R, Hickman D, Uppal N, Shoffstall A, Ustin J, Lavik E Bioconjugate chemistry 29965731 Bioconjug Chem 2018 Jul 18 https://www.ncbi.nlm.nih.gov/pubmed/29965731
Engineering therapies in the CNS: what works and what can be translated. Shoffstall AJ, Taylor DM, Lavik EB Neuroscience letters 22330751 Neurosci Lett 2012 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/22330751
Novel drug delivery systems for glaucoma. Lavik E, Kuehn MH, Kwon YH Eye (London, England) 21475311 Eye (Lond) 2011 May https://www.ncbi.nlm.nih.gov/pubmed/21475311
Controlled release of photoswitch drugs by degradable polymer microspheres. Groynom R, Shoffstall E, Wu LS, Kramer RH, Lavik EB Journal of drug targeting 26453166 J Drug Target 2015 https://www.ncbi.nlm.nih.gov/pubmed/26453166
Materials design at the interface of nanoparticles and innate immunity. Szeto GL, Lavik EB Journal of materials chemistry. B 27453783 J Mater Chem B 2016 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/27453783
Tuning ligand density on intravenous hemostatic nanoparticles dramatically increases survival following blunt trauma. Shoffstall AJ, Everhart LM, Varley ME, Soehnlen ES, Shick AM, Ustin JS, Lavik EB Biomacromolecules 23841817 Biomacromolecules 2013 Aug 12 https://www.ncbi.nlm.nih.gov/pubmed/23841817
Intravenous hemostatic nanoparticles increase survival following blunt trauma injury. Shoffstall AJ, Atkins KT, Groynom RE, Varley ME, Everhart LM, Lashof-Sullivan MM, Martyn-Dow B, Butler RS, Ustin JS, Lavik EB Biomacromolecules 22998772 Biomacromolecules 2012 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/22998772
Olfactory ensheathing cells promote differentiation of neural stem cells and robust neurite extension. Sethi R, Sethi R, Redmond A, Lavik E Stem cell reviews and reports 24996386 Stem Cell Rev Rep 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/24996386
Sustained Delivery of Timolol Maleate for Over 90 Days by Subconjunctival Injection. Lavik E, Kuehn MH, Shoffstall AJ, Atkins K, Dumitrescu AV, Kwon YH Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 27835065 J Ocul Pharmacol Ther 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27835065
Examining lethality risk for rodent studies of primary blast lung injury. Hubbard WB, Hall C, Siva Sai Suijith Sajja V, Lavik E, VandeVord P Biomedical sciences instrumentation 25405409 Biomed Sci Instrum 2014 https://www.ncbi.nlm.nih.gov/pubmed/25405409
Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues. Wang R, Zheng W, Yu H, Deng H, Luo M Journal of the American Chemical Society 21539310 J Am Chem Soc 2011 May 25 https://www.ncbi.nlm.nih.gov/pubmed/21539310
A sensitive mass spectrum assay to characterize engineered methionine adenosyltransferases with S-alkyl methionine analogues as substrates. Wang R, Zheng W, Luo M Analytical biochemistry 24374249 Anal Biochem 2014 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/24374249
Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Islam K, Chen Y, Wu H, Bothwell IR, Blum GJ, Zeng H, Dong A, Zheng W, Min J, Deng H, Luo M Proceedings of the National Academy of Sciences of the United States of America 24082136 Proc Natl Acad Sci U S A 2013 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/24082136
A high throughput scintillation proximity imaging assay for protein methyltransferases. Ibanez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, Luo M, Djaballah H Combinatorial chemistry & high throughput screening 22256970 Comb Chem High Throughput Screen 2012 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/22256970
Current chemical biology approaches to interrogate protein methyltransferases. Luo M ACS chemical biology 22220966 ACS Chem Biol 2012 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/22220966
Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors. Wang R, Ibáñez G, Islam K, Zheng W, Blum G, Sengelaub C, Luo M Molecular bioSystems 21866297 Mol Biosyst 2011 Nov https://www.ncbi.nlm.nih.gov/pubmed/21866297
Facile synthesis and altered ionization efficiency of diverse Nε-alkyllysine-containing peptides. Chakraborty D, Islam K, Luo M Chemical communications (Cambridge, England) 21959946 Chem Commun (Camb) 2012 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/21959946
Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling. Islam K, Zheng W, Yu H, Deng H, Luo M ACS chemical biology 21495674 ACS Chem Biol 2011 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/21495674
A journey toward Bioorthogonal Profiling of Protein Methylation inside living cells. Wang R, Luo M Current opinion in chemical biology 24035694 Curr Opin Chem Biol 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/24035694
Small-molecule inhibitors of SETD8 with cellular activity. Blum G, Ibáñez G, Rao X, Shum D, Radu C, Djaballah H, Rice JC, Luo M ACS chemical biology 25137013 ACS Chem Biol 2014 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/25137013
Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine. Islam K, Bothwell I, Chen Y, Sengelaub C, Wang R, Deng H, Luo M Journal of the American Chemical Society 22404544 J Am Chem Soc 2012 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/22404544
Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents. Aldawsari FS, Aguayo-Ortiz R, Kapilashrami K, Yoo J, Luo M, Medina-Franco JL, Velázquez-Martínez CA Journal of enzyme inhibition and medicinal chemistry 26118420 J Enzyme Inhib Med Chem 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/26118420
Profiling substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues. Guo H, Wang R, Zheng W, Chen Y, Blum G, Deng H, Luo M ACS chemical biology 24320160 ACS Chem Biol 2014 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/24320160
Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation. Bothwell IR, Islam K, Chen Y, Zheng W, Blum G, Deng H, Luo M Journal of the American Chemical Society 22917021 J Am Chem Soc 2012 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/22917021
Bioorthogonal profiling of protein methylation (BPPM) using an azido analog of S-adenosyl-L-methionine. Blum G, Islam K, Luo M Current protocols in chemical biology 23667794 Curr Protoc Chem Biol 2013 https://www.ncbi.nlm.nih.gov/pubmed/23667794
Inhibitors of protein methyltransferases as chemical tools. Luo M Epigenomics 26646500 Epigenomics 2015 https://www.ncbi.nlm.nih.gov/pubmed/26646500
Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. Winter JM, Chiou G, Bothwell IR, Xu W, Garg NK, Luo M, Tang Y Organic letters 23837609 Org Lett 2013 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/23837609
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Drug-Initiated, Controlled Ring-Opening Polymerization for the Synthesis of Polymer-Drug Conjugates. Tong R, Cheng J Macromolecules 23357880 Macromolecules 2012 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/23357880
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CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells. Myers DE, Yiv S, Qazi S, Ma H, Cely I, Shahidzadeh A, Arellano M, Finestone E, Gaynon PS, Termuhlen A, Cheng J, Uckun FM Integrative biology : quantitative biosciences from nano to macro 24910947 Integr Biol (Camb) 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24910947
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Investigating the optimal size of anticancer nanomedicine. Tang L, Yang X, Yin Q, Cai K, Wang H, Chaudhury I, Yao C, Zhou Q, Kwon M, Hartman JA, Dobrucki IT, Dobrucki LW, Borst LB, Lezmi S, Helferich WG, Ferguson AL, Fan TM, Cheng J Proceedings of the National Academy of Sciences of the United States of America 25316794 Proc Natl Acad Sci U S A 2014 Oct 28 https://www.ncbi.nlm.nih.gov/pubmed/25316794
Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cells. Yen J, Zhang Y, Gabrielson NP, Yin L, Guan L, Chaudhury I, Lu H, Wang F, Cheng J Biomaterials science 23997932 Biomater Sci 2013 Jul https://www.ncbi.nlm.nih.gov/pubmed/23997932
Polypeptides with quaternary phosphonium side chains: synthesis, characterization, and cell-penetrating properties. Song Z, Zheng N, Ba X, Yin L, Zhang R, Ma L, Cheng J Biomacromolecules 24635536 Biomacromolecules 2014 Apr 14 https://www.ncbi.nlm.nih.gov/pubmed/24635536
Water-soluble poly(L-serine)s with elongated and charged side-chains: synthesis, conformations, and cell-penetrating properties. Tang H, Yin L, Lu H, Cheng J Biomacromolecules 22853191 Biomacromolecules 2012 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/22853191
Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A. Tang L, Azzi J, Kwon M, Mounayar M, Tong R, Yin Q, Moore R, Skartsis N, Fan TM, Abdi R, Cheng J Journal of transplantation 22545201 J Transplant 2012 https://www.ncbi.nlm.nih.gov/pubmed/22545201
Design of Albumin-Coated Microbubbles Loaded With Polylactide Nanoparticles. Gauthier M, Yin Q, Cheng J, O'Brien WD Jr Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 26206822 J Ultrasound Med 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26206822
Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-Site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-Precursor Leukemia and Yield Superior Survival Outcomes in Mice. Uckun FM, Myers DE, Cheng J, Qazi S EBioMedicine 26285772 EBioMedicine 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/26285772
Poly(iohexol) nanoparticles as contrast agents for in vivo X-ray computed tomography imaging. Yin Q, Yap FY, Yin L, Ma L, Zhou Q, Dobrucki LW, Fan TM, Gaba RC, Cheng J Journal of the American Chemical Society 23987119 J Am Chem Soc 2013 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/23987119
PEG-Polypeptide Dual Brush Block Copolymers: Synthesis and Application in Nanoparticle Surface PEGylation. Zhang Y, Yin Q, Lu H, Xia H, Lin Y, Cheng J ACS macro letters 24159425 ACS Macro Lett 2013 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/24159425
Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting. Zheng N, Yin L, Song Z, Ma L, Tang H, Gabrielson NP, Lu H, Cheng J Biomaterials 24211080 Biomaterials 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/24211080
Dimeric drug polymeric nanoparticles with exceptionally high drug loading and quantitative loading efficiency. Cai K, He X, Song Z, Yin Q, Zhang Y, Uckun FM, Jiang C, Cheng J Journal of the American Chemical Society 25741752 J Am Chem Soc 2015 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/25741752
Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics. Cai K, Yen J, Yin Q, Liu Y, Song Z, Lezmi S, Zhang Y, Yang X, Helferich WG, Cheng J Biomaterials science 26146551 Biomater Sci 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/26146551
In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates. Wang H, Tang L, Liu Y, Dobrucka IT, Dobrucki LW, Yin L, Cheng J Theranostics 27375793 Theranostics 2016 https://www.ncbi.nlm.nih.gov/pubmed/27375793
Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultra-Stable Helical Conformations. Zhang Y, Lu H, Lin Y, Cheng J Macromolecules 22049249 Macromolecules 2011 Sep 13 https://www.ncbi.nlm.nih.gov/pubmed/22049249
Ring-Opening Polymerization of γ-(4-Vinylbenzyl)-(L)-Glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides. Lu H, Bai Y, Wang J, Gabrielson NP, Wang F, Lin Y, Cheng J Macromolecules 22121300 Macromolecules 2011 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/22121300
Dynamic urea bond for the design of reversible and self-healing polymers. Ying H, Zhang Y, Cheng J Nature communications 24492620 Nat Commun 2014 https://www.ncbi.nlm.nih.gov/pubmed/24492620
The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides. Zhang R, Zheng N, Song Z, Yin L, Cheng J Biomaterials 24439403 Biomaterials 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24439403
Targeted Ultrasound-Assisted Cancer-Selective Chemical Labeling and Subsequent Cancer Imaging using Click Chemistry. Wang H, Gauthier M, Kelly JR, Miller RJ, Xu M, O'Brien WD Jr, Cheng J Angewandte Chemie (International ed. in English) 27010510 Angew Chem Int Ed Engl 2016 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/27010510
Selective in vivo metabolic cell-labeling-mediated cancer targeting. Wang H, Wang R, Cai K, He H, Liu Y, Yen J, Wang Z, Xu M, Sun Y, Zhou X, Yin Q, Tang L, Dobrucki IT, Dobrucki LW, Chaney EJ, Boppart SA, Fan TM, Lezmi S, Chen X, Yin L, Cheng J Nature chemical biology 28192414 Nat Chem Biol 2017 Apr https://www.ncbi.nlm.nih.gov/pubmed/28192414
Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates. Tang L, Gabrielson NP, Uckun FM, Fan TM, Cheng J Molecular pharmaceutics 23301497 Mol Pharm 2013 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/23301497
Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles. Cely I, Yiv S, Yin Q, Shahidzadeh A, Tang L, Cheng J, Uckun FM Journal of analytical oncology 23730399 J Anal Oncol 2012 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/23730399
Polymeric Nanomedicines Based on Poly(lactide) and Poly(lactide-co-glycolide). Tong R, Gabrielson NP, Fan TM, Cheng J Current opinion in solid state & materials science 23914135 Curr Opin Solid State Mater Sci 2012 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/23914135
Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery. Yin L, Song Z, Kim KH, Zheng N, Tang H, Lu H, Gabrielson N, Cheng J Biomaterials 23283350 Biomaterials 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23283350
Non-viral gene delivery via membrane-penetrating, mannose-targeting supramolecular self-assembled nanocomplexes. Yin L, Song Z, Kim KH, Zheng N, Gabrielson NP, Cheng J Advanced materials (Deerfield Beach, Fla.) 23417835 Adv Mater 2013 Jun 11 https://www.ncbi.nlm.nih.gov/pubmed/23417835
Trigger-responsive, fast-degradable poly(β-amino ester)s for enhanced DNA unpackaging and reduced toxicity. Deng X, Zheng N, Song Z, Yin L, Cheng J Biomaterials 24674461 Biomaterials 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24674461
Redox-responsive, core-cross-linked micelles capable of on-demand, concurrent drug release and structure disassembly. Wang H, Tang L, Tu C, Song Z, Yin Q, Yin L, Zhang Z, Cheng J Biomacromolecules 24003893 Biomacromolecules 2013 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/24003893
CD22ΔE12 as a molecular target for RNAi therapy. Uckun FM, Ma H, Cheng J, Myers DE, Qazi S British journal of haematology 25659406 Br J Haematol 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25659406
Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo. Xing H, Tang L, Yang X, Hwang K, Wang W, Yin Q, Wong NY, Dobrucki LW, Yasui N, Katzenellenbogen JA, Helferich WG, Cheng J, Lu Y Journal of materials chemistry. B 24159374 J Mater Chem B 2013 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/24159374
Helical Poly(arginine) Mimics with Superior Cell-Penetrating and Molecular Transporting Properties. Tang H, Yin L, Kim KH, Cheng J Chemical science 25400902 Chem Sci 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/25400902
Hydrolyzable polyureas bearing hindered urea bonds. Ying H, Cheng J Journal of the American Chemical Society 25406025 J Am Chem Soc 2014 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/25406025
A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies. Uckun FM, Qazi S, Ma H, Yin L, Cheng J EBioMedicine 25599086 EBioMedicine 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25599086
Reactive and bioactive cationic α-helical polypeptide template for nonviral gene delivery. Gabrielson NP, Lu H, Yin L, Li D, Wang F, Cheng J Angewandte Chemie (International ed. in English) 22162307 Angew Chem Int Ed Engl 2012 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/22162307
Enhanced Non-Viral Gene Delivery to Human Embryonic Stem Cells via Small Molecule-Mediated Transient Alteration of Cell Structure. Yen J, Yin L, Cheng J Journal of materials chemistry. B 26005572 J Mater Chem B 2014 https://www.ncbi.nlm.nih.gov/pubmed/26005572
Targeting tumor vasculature with aptamer-functionalized doxorubicin-polylactide nanoconjugates for enhanced cancer therapy. Tang L, Tong R, Coyle VJ, Yin Q, Pondenis H, Borst LB, Cheng J, Fan TM ACS nano 25938427 ACS Nano 2015 May 26 https://www.ncbi.nlm.nih.gov/pubmed/25938427
Targeting leukemic stem cells with multifunctional bioactive polypeptide nanoparticles. Uckun FM, Qazi S, Cheng J Future oncology (London, England) 25832872 Future Oncol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25832872
Development of Polypeptide-based Nanoparticles for Non-viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL. Uckun FM, Mitchell LG, Qazi S, Liu Y, Zheng N, Myers DE, Song Z, Ma H, Cheng J EBioMedicine 26288837 EBioMedicine 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/26288837
Facile functionalization of polyesters through thiol-yne chemistry for the design of degradable, cell-penetrating and gene delivery dual-functional agents. Zhang Z, Yin L, Xu Y, Tong R, Lu Y, Ren J, Cheng J Biomacromolecules 23098261 Biomacromolecules 2012 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/23098261
Polyvalent mesoporous silica nanoparticle-aptamer bioconjugates target breast cancer cells. Li LL, Yin Q, Cheng J, Lu Y Advanced healthcare materials 23184791 Adv Healthc Mater 2012 Sep https://www.ncbi.nlm.nih.gov/pubmed/23184791
Synthesis of water-soluble poly(α-hydroxy acids) from living ring-opening polymerization of O-benzyl-L-serine carboxyanhydrides. Lu Y, Yin L, Zhang Y, Zhonghai Z, Xu Y, Tong R, Cheng J ACS macro letters 23359651 ACS Macro Lett 2012 Apr 17 https://www.ncbi.nlm.nih.gov/pubmed/23359651
Manipulating the membrane penetration mechanism of helical polypeptides via aromatic modification for efficient gene delivery. Zheng N, Song Z, Yang J, Liu Y, Li F, Cheng J, Yin L Acta biomaterialia 28476586 Acta Biomater 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28476586
Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation. Yin L, Song Z, Qu Q, Kim KH, Zheng N, Yao C, Chaudhury I, Tang H, Gabrielson NP, Uckun FM, Cheng J Angewandte Chemie (International ed. in English) 23610013 Angew Chem Int Ed Engl 2013 May 27 https://www.ncbi.nlm.nih.gov/pubmed/23610013
Chain-shattering polymeric therapeutics with on-demand drug-release capability. Zhang Y, Yin Q, Yin L, Ma L, Tang L, Cheng J Angewandte Chemie (International ed. in English) 23650111 Angew Chem Int Ed Engl 2013 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/23650111
Nonporous Silica Nanoparticles for Nanomedicine Application. Tang L, Cheng J Nano today 23997809 Nano Today 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23997809
Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis. Yin Q, Tang L, Cai K, Tong R, Sternberg R, Yang X, Dobrucki LW, Borst LB, Kamstock D, Song Z, Helferich WG, Cheng J, Fan TM Proceedings of the National Academy of Sciences of the United States of America 27457945 Proc Natl Acad Sci U S A 2016 Aug 9 https://www.ncbi.nlm.nih.gov/pubmed/27457945
In vivo cancer targeting via glycopolyester nanoparticle mediated metabolic cell labeling followed by click reaction. Wang H, Bo Y, Liu Y, Xu M, Cai K, Wang R, Cheng J Biomaterials 31323538 Biomaterials 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31323538
Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia. Uckun FM, Qazi S, Cely I, Sahin K, Shahidzadeh A, Ozercan I, Yin Q, Gaynon P, Termuhlen A, Cheng J, Yiv S Blood 23568490 Blood 2013 May 23 https://www.ncbi.nlm.nih.gov/pubmed/23568490
Drug-initiated ring-opening polymerization of O-carboxyanhydrides for the preparation of anticancer drug-poly(O-carboxyanhydride) nanoconjugates. Yin Q, Tong R, Xu Y, Baek K, Dobrucki LW, Fan TM, Cheng J Biomacromolecules 23445497 Biomacromolecules 2013 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/23445497
Light-responsive helical polypeptides capable of reducing toxicity and unpacking DNA: toward nonviral gene delivery. Yin L, Tang H, Kim KH, Zheng N, Song Z, Gabrielson NP, Lu H, Cheng J Angewandte Chemie (International ed. in English) 23832670 Angew Chem Int Ed Engl 2013 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/23832670
A cell-penetrating helical polymer for siRNA delivery to mammalian cells. Gabrielson NP, Lu H, Yin L, Kim KH, Cheng J Molecular therapy : the journal of the American Society of Gene Therapy 22643866 Mol Ther 2012 Aug https://www.ncbi.nlm.nih.gov/pubmed/22643866
Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates. Tang L, Fan TM, Borst LB, Cheng J ACS nano 22494403 ACS Nano 2012 May 22 https://www.ncbi.nlm.nih.gov/pubmed/22494403
Ionic polypeptides with unusual helical stability. Lu H, Wang J, Bai Y, Lang JW, Liu S, Lin Y, Cheng J Nature communications 21343924 Nat Commun 2011 Feb 22 https://www.ncbi.nlm.nih.gov/pubmed/21343924
Helical antimicrobial polypeptides with radial amphiphilicity. Xiong M, Lee MW, Mansbach RA, Song Z, Bao Y, Peek RM Jr, Yao C, Chen LF, Ferguson AL, Wong GC, Cheng J Proceedings of the National Academy of Sciences of the United States of America 26460016 Proc Natl Acad Sci U S A 2015 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/26460016
Ionic α-helical polypeptides toward nonviral gene delivery. Zhang R, Song Z, Yin L, Zheng N, Tang H, Lu H, Gabrielson NP, Lin Y, Kim K, Cheng J Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 25377262 Wiley Interdiscip Rev Nanomed Nanobiotechnol 2015 Jan-Feb https://www.ncbi.nlm.nih.gov/pubmed/25377262
Synthesis of hybrid block copolymers via integrated ring-opening metathesis polymerization and polymerization of NCA. Bai Y, Lu H, Ponnusamy E, Cheng J Chemical communications (Cambridge, England) 21869956 Chem Commun (Camb) 2011 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/21869956
Anticancer Camptothecin-N-Poly(lactic acid) Nanoconjugates with Facile Hydrolysable Linker. Yin Q, Tong R, Yin L, Fan TM, Cheng J Polymer chemistry 26005498 Polym Chem 2014 https://www.ncbi.nlm.nih.gov/pubmed/26005498
Dual Stimuli-Responsive Poly(β-amino ester) Nanoparticles for On-Demand Burst Release. Lee JS, Deng X, Han P, Cheng J Macromolecular bioscience 26036966 Macromol Biosci 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26036966
Bioorthogonal Oxime Ligation Mediated In Vivo Cancer Targeting. Tang L, Yin Q, Xu Y, Zhou Q, Cai K, Yen J, Dobrucki LW, Cheng J Chemical science 26146536 Chem Sci 2015 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/26146536
Synthesis and biomedical applications of functional poly(α-hydroxy acids) via ring-opening polymerization of O-carboxyanhydrides. Yin Q, Yin L, Wang H, Cheng J Accounts of chemical research 26065588 Acc Chem Res 2015 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/26065588
Biodegradable micelles capable of mannose-mediated targeted drug delivery to cancer cells. Yin L, Chen Y, Zhang Z, Yin Q, Zheng N, Cheng J Macromolecular rapid communications 25619623 Macromol Rapid Commun 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25619623
Reduction-responsive dithiomaleimide-based nanomedicine with high drug loading and FRET-indicated drug release. Wang H, Xu M, Xiong M, Cheng J Chemical communications (Cambridge, England) 25692778 Chem Commun (Camb) 2015 Mar 21 https://www.ncbi.nlm.nih.gov/pubmed/25692778
Molecular simulations of aromatase reveal new insights into the mechanism of ligand binding. Park J, Czapla L, Amaro RE Journal of chemical information and modeling 23927370 J Chem Inf Model 2013 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/23927370
The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution. Rathore A, Carpenter MA, Demir Ö, Ikeda T, Li M, Shaban NM, Law EK, Anokhin D, Brown WL, Amaro RE, Harris RS Journal of molecular biology 23938202 J Mol Biol 2013 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/23938202
Designing novel inhibitors of Trypanosoma brucei. Demir O, Amaro RE Methods in molecular biology (Clifton, N.J.) 23568474 Methods Mol Biol 2013 https://www.ncbi.nlm.nih.gov/pubmed/23568474
Electrostatic Interactions as Mediators in the Allosteric Activation of Protein Kinase A RIα. P Barros E, Malmstrom RD, Nourbakhsh K, Del Rio JC, Kornev AP, Taylor SS, Amaro RE Biochemistry 28221775 Biochemistry 2017 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/28221775
WebChem Viewer: a tool for the easy dissemination of chemical and structural data sets. Durrant JD, Amaro RE BMC bioinformatics 24886360 BMC Bioinformatics 2014 May 23 https://www.ncbi.nlm.nih.gov/pubmed/24886360
Mesoscale All-Atom Influenza Virus Simulations Suggest New Substrate Binding Mechanism. Durrant JD, Kochanek SE, Casalino L, Ieong PU, Dommer AC, Amaro RE ACS central science 32123736 ACS Cent Sci 2020 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/32123736
The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release. Bohl HO, Ieong P, Lee JK, Lee T, Kankanala J, Shi K, Demir Ö, Kurahashi K, Amaro RE, Wang Z, Aihara H The Journal of biological chemistry 29626094 J Biol Chem 2018 May 25 https://www.ncbi.nlm.nih.gov/pubmed/29626094
A novel high-throughput activity assay for the Trypanosoma brucei editosome enzyme REL1 and other RNA ligases. Zimmermann S, Hall L, Riley S, Sørensen J, Amaro RE, Schnaufer A Nucleic acids research 26400159 Nucleic Acids Res 2016 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/26400159
The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches. Richards C, Albin JS, Demir Ö, Shaban NM, Luengas EM, Land AM, Anderson BD, Holten JR, Anderson JS, Harki DA, Amaro RE, Harris RS Cell reports 26628363 Cell Rep 2015 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/26628363
Structural characterisation of Tpx from Yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds. Gabrielsen M, Beckham KS, Feher VA, Zetterström CE, Wang D, Müller S, Elofsson M, Amaro RE, Byron O, Roe AJ PloS one 22384182 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/22384182
Rational prediction with molecular dynamics for hit identification. Nichols SE, Swift RV, Amaro RE Current topics in medicinal chemistry 23110535 Curr Top Med Chem 2012 https://www.ncbi.nlm.nih.gov/pubmed/23110535
Molecular-level simulation of pandemic influenza glycoproteins. Amaro RE, Li WW Methods in molecular biology (Clifton, N.J.) 22183559 Methods Mol Biol 2012 https://www.ncbi.nlm.nih.gov/pubmed/22183559
Microsecond Molecular Dynamics Simulations of Influenza Neuraminidase Suggest a Mechanism for the Increased Virulence of Stalk-Deletion Mutants. Durrant JD, Bush RM, Amaro RE The journal of physical chemistry. B 27141956 J Phys Chem B 2016 Aug 25 https://www.ncbi.nlm.nih.gov/pubmed/27141956
Multiscale Estimation of Binding Kinetics Using Brownian Dynamics, Molecular Dynamics and Milestoning. Votapka LW, Amaro RE PLoS computational biology 26505480 PLoS Comput Biol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26505480
Bridging scales through multiscale modeling: a case study on protein kinase A. Boras BW, Hirakis SP, Votapka LW, Malmstrom RD, Amaro RE, McCulloch AD Frontiers in physiology 26441670 Front Physiol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26441670
Efficient Calculation of Accurate Reaction Energies-Assessment of Different Models in Electronic Structure Theory. Friedrich J Journal of chemical theory and computation 26574443 J Chem Theory Comput 2015 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/26574443
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B. Shi K, Carpenter MA, Banerjee S, Shaban NM, Kurahashi K, Salamango DJ, McCann JL, Starrett GJ, Duffy JV, Demir Ö, Amaro RE, Harki DA, Harris RS, Aihara H Nature structural & molecular biology 27991903 Nat Struct Mol Biol 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/27991903
Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit. Mulero MC, Shahabi S, Ko MS, Schiffer JM, Huang DB, Wang VY, Amaro RE, Huxford T, Ghosh G Biochemistry 29708732 Biochemistry 2018 May 22 https://www.ncbi.nlm.nih.gov/pubmed/29708732
Modeling the pharmacodynamics of passive membrane permeability. Swift RV, Amaro RE Journal of computer-aided molecular design 22042376 J Comput Aided Mol Des 2011 Nov https://www.ncbi.nlm.nih.gov/pubmed/22042376
Mechanism of 150-cavity formation in influenza neuraminidase. Amaro RE, Swift RV, Votapka L, Li WW, Walker RC, Bush RM Nature communications 21750542 Nat Commun 2011 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/21750542
Machine-learning techniques applied to antibacterial drug discovery. Durrant JD, Amaro RE Chemical biology & drug design 25521642 Chem Biol Drug Des 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25521642
Enhancing Virtual Screening Performance of Protein Kinases with Molecular Dynamics Simulations. Offutt TL, Swift RV, Amaro RE Journal of chemical information and modeling 27662181 J Chem Inf Model 2016 Oct 24 https://www.ncbi.nlm.nih.gov/pubmed/27662181
POVME 3.0: Software for Mapping Binding Pocket Flexibility. Wagner JR, Sørensen J, Hensley N, Wong C, Zhu C, Perison T, Amaro RE Journal of chemical theory and computation 28800393 J Chem Theory Comput 2017 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/28800393
Capturing Invisible Motions in the Transition from Ground to Rare Excited States of T4 Lysozyme L99A. Schiffer JM, Feher VA, Malmstrom RD, Sida R, Amaro RE Biophysical journal 27760351 Biophys J 2016 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/27760351
Multistructural hot spot characterization with FTProd. Votapka L, Amaro RE Bioinformatics (Oxford, England) 23202744 Bioinformatics 2013 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/23202744
Exploring residue component contributions to dynamical network models of allostery. Vanwart AT, Eargle J, Luthey-Schulten Z, Amaro RE Journal of chemical theory and computation 23139645 J Chem Theory Comput 2012 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/23139645
A 3-dimensional trimeric β-barrel model for Chlamydia MOMP contains conserved and novel elements of Gram-negative bacterial porins. Feher VA, Randall A, Baldi P, Bush RM, de la Maza LM, Amaro RE PloS one 23935908 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23935908
Molecular docking to flexible targets. Sørensen J, Demir Ö, Swift RV, Feher VA, Amaro RE Methods in molecular biology (Clifton, N.J.) 25330975 Methods Mol Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25330975
Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester. Castro-Falcón G, Seiler GS, Demir Ö, Rathinaswamy MK, Hamelin D, Hoffmann RM, Makowski SL, Letzel AC, Field SJ, Burke JE, Amaro RE, Hughes CC Journal of medicinal chemistry 30380865 J Med Chem 2018 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/30380865
Structural basis for ligand modulation of the CCR2 conformational landscape. Taylor BC, Lee CT, Amaro RE Proceedings of the National Academy of Sciences of the United States of America 30975755 Proc Natl Acad Sci U S A 2019 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/30975755
Allostery through the computational microscope: cAMP activation of a canonical signalling domain. Malmstrom RD, Kornev AP, Taylor SS, Amaro RE Nature communications 26145448 Nat Commun 2015 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/26145448
Quantitative Ranking of Ligand Binding Kinetics with a Multiscale Milestoning Simulation Approach. Jagger BR, Lee CT, Amaro RE The journal of physical chemistry letters 30070844 J Phys Chem Lett 2018 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/30070844
Multiscale Methods in Drug Design Bridge Chemical and Biological Complexity in the Search for Cures. Amaro RE, Mulholland AJ Nature reviews. Chemistry 30949587 Nat Rev Chem 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/30949587
On the Application of Molecular-Dynamics Based Markov State Models to Functional Proteins. Malmstrom RD, Lee CT, Van Wart A, Amaro RE Journal of chemical theory and computation 25473382 J Chem Theory Comput 2014 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/25473382
A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity. Ikram NK, Durrant JD, Muchtaridi M, Zalaludin AS, Purwitasari N, Mohamed N, Rahim AS, Lam CK, Normi YM, Rahman NA, Amaro RE, Wahab HA Journal of chemical information and modeling 25555059 J Chem Inf Model 2015 Feb 23 https://www.ncbi.nlm.nih.gov/pubmed/25555059
Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants. Demir Ö, Baronio R, Salehi F, Wassman CD, Hall L, Hatfield GW, Chamberlin R, Kaiser P, Lathrop RH, Amaro RE PLoS computational biology 22028641 PLoS Comput Biol 2011 Oct https://www.ncbi.nlm.nih.gov/pubmed/22028641
Molecular dynamics analysis of antibody recognition and escape by human H1N1 influenza hemagglutinin. Ieong P, Amaro RE, Li WW Biophysical journal 26039171 Biophys J 2015 Jun 2 https://www.ncbi.nlm.nih.gov/pubmed/26039171
Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands. Durrant JD, Carlson KE, Martin TA, Offutt TL, Mayne CG, Katzenellenbogen JA, Amaro RE Journal of chemical information and modeling 26286148 J Chem Inf Model 2015 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/26286148
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53. Wassman CD, Baronio R, Demir Ö, Wallentine BD, Chen CK, Hall LV, Salehi F, Lin DW, Chung BP, Hatfield GW, Richard Chamberlin A, Luecke H, Lathrop RH, Kaiser P, Amaro RE Nature communications 23360998 Nat Commun 2013 https://www.ncbi.nlm.nih.gov/pubmed/23360998
Magnesium-induced nucleophile activation in the guanylyltransferase mRNA capping enzyme. Swift RV, Ong CD, Amaro RE Biochemistry 23205906 Biochemistry 2012 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/23205906
Teach-Discover-Treat (TDT): collaborative computational drug discovery for neglected diseases. Jansen JM, Cornell W, Tseng YJ, Amaro RE Journal of molecular graphics & modelling 23085175 J Mol Graph Model 2012 Sep https://www.ncbi.nlm.nih.gov/pubmed/23085175
Mechanisms for Benzene Dissociation through the Excited State of T4 Lysozyme L99A Mutant. Feher VA, Schiffer JM, Mermelstein DJ, Mih N, Pierce LCT, McCammon JA, Amaro RE Biophysical journal 30606449 Biophys J 2019 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/30606449
Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B. Shi K, Demir Ö, Carpenter MA, Banerjee S, Harki DA, Amaro RE, Harris RS, Aihara H FASEB bioAdvances 32123856 FASEB Bioadv 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/32123856
Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases. Prabhu L, Chen L, Wei H, Demir Ö, Safa A, Zeng L, Amaro RE, O'Neil BH, Zhang ZY, Lu T Molecular bioSystems 29099132 Mol Biosyst 2017 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/29099132
Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B. Shi K, Demir Ö, Carpenter MA, Wagner J, Kurahashi K, Harris RS, Amaro RE, Aihara H Scientific reports 29234087 Sci Rep 2017 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/29234087
Simulation-Based Approaches for Determining Membrane Permeability of Small Compounds. Lee CT, Comer J, Herndon C, Leung N, Pavlova A, Swift RV, Tung C, Rowley CN, Amaro RE, Chipot C, Wang Y, Gumbart JC Journal of chemical information and modeling 27043429 J Chem Inf Model 2016 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/27043429
A Kepler Workflow Tool for Reproducible AMBER GPU Molecular Dynamics. Purawat S, Ieong PU, Malmstrom RD, Chan GJ, Yeung AK, Walker RC, Altintas I, Amaro RE Biophysical journal 28636905 Biophys J 2017 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/28636905
Computation-guided discovery of influenza endonuclease inhibitors. Chen E, Swift RV, Alderson N, Feher VA, Feng GS, Amaro RE ACS medicinal chemistry letters 24490002 ACS Med Chem Lett 2014 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/24490002
Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Buffalo CZ, Bahn-Suh AJ, Hirakis SP, Biswas T, Amaro RE, Nizet V, Ghosh P Nature microbiology 27595425 Nat Microbiol 2016 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/27595425
SEEKR: Simulation Enabled Estimation of Kinetic Rates, A Computational Tool to Estimate Molecular Kinetics and Its Application to Trypsin-Benzamidine Binding. Votapka LW, Jagger BR, Heyneman AL, Amaro RE The journal of physical chemistry. B 28191969 J Phys Chem B 2017 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/28191969
Variable ligand- and receptor-binding hot spots in key strains of influenza neuraminidase. Votapka L, Demir O, Swift RV, Walker RC, Amaro RE Journal of molecular and genetic medicine : an international journal of biomedical research 22872804 J Mol Genet Med 2012 https://www.ncbi.nlm.nih.gov/pubmed/22872804
Elements of nucleotide specificity in the Trypanosoma brucei mitochondrial RNA editing enzyme RET2. Demir Ö, Amaro RE Journal of chemical information and modeling 22512810 J Chem Inf Model 2012 May 25 https://www.ncbi.nlm.nih.gov/pubmed/22512810
Back to the future: can physical models of passive membrane permeability help reduce drug candidate attrition and move us beyond QSPR? Swift RV, Amaro RE Chemical biology & drug design 23066853 Chem Biol Drug Des 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/23066853
Computational chemistry and drug discovery: a call to action. Jansen JM, Amaro RE, Cornell W, Tseng YJ, Walters WP Future medicinal chemistry 23088271 Future Med Chem 2012 Oct https://www.ncbi.nlm.nih.gov/pubmed/23088271
Computational approaches to mapping allosteric pathways. Feher VA, Durrant JD, Van Wart AT, Amaro RE Current opinion in structural biology 24667124 Curr Opin Struct Biol 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24667124
LipidWrapper: an algorithm for generating large-scale membrane models of arbitrary geometry. Durrant JD, Amaro RE PLoS computational biology 25032790 PLoS Comput Biol 2014 Jul https://www.ncbi.nlm.nih.gov/pubmed/25032790
Weighted Implementation of Suboptimal Paths (WISP): An Optimized Algorithm and Tool for Dynamical Network Analysis. Van Wart AT, Durrant J, Votapka L, Amaro RE Journal of chemical theory and computation 24803851 J Chem Theory Comput 2014 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/24803851
RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting. Rajappa-Titu L, Suematsu T, Munoz-Tello P, Long M, Demir Ö, Cheng KJ, Stagno JR, Luecke H, Amaro RE, Aphasizheva I, Aphasizhev R, Thore S Nucleic acids research 27744351 Nucleic Acids Res 2016 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/27744351
Computer-aided discovery of Trypanosoma brucei RNA-editing terminal uridylyl transferase 2 inhibitors. Demir O, Labaied M, Merritt C, Stuart K, Amaro RE Chemical biology & drug design 24903413 Chem Biol Drug Des 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24903413
A Computational Assay that Explores the Hemagglutinin/Neuraminidase Functional Balance Reveals the Neuraminidase Secondary Site as a Novel Anti-Influenza Target. Amaro RE, Ieong PU, Huber G, Dommer A, Steven AC, Bush RM, Durrant JD, Votapka LW ACS central science 30555910 ACS Cent Sci 2018 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/30555910
Determinants of Oligonucleotide Selectivity of APOBEC3B. Wagner JR, Demir Ö, Carpenter MA, Aihara H, Harki DA, Harris RS, Amaro RE Journal of chemical information and modeling 30130104 J Chem Inf Model 2019 May 28 https://www.ncbi.nlm.nih.gov/pubmed/30130104
Progress towards automated Kepler scientific workflows for computer-aided drug discovery and molecular simulations. Ieong PU, Sørensen J, Vemu PL, Wong CW, Demir Ö, Williams NP, Wang J, Crawl D, Swift RV, Malmstrom RD, Altintas I, Amaro RE Procedia computer science 29399238 Procedia Comput Sci 2014 https://www.ncbi.nlm.nih.gov/pubmed/29399238
Molecular Simulations Reveal an Unresolved Conformation of the Type IA Protein Kinase A Regulatory Subunit and Suggest Its Role in the cAMP Regulatory Mechanism. Hirakis SP, Malmstrom RD, Amaro RE Biochemistry 28661131 Biochemistry 2017 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/28661131
A Comparative Study of the Structural Dynamics of Four Terminal Uridylyl Transferases. Cheng KJ, Demir Ö, Amaro RE Genes 28632168 Genes (Basel) 2017 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/28632168
Dynamics and Molecular Mechanisms of p53 Transcriptional Activation. Offutt TL, Ieong PU, Demir Ö, Amaro RE Biochemistry 30388364 Biochemistry 2018 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/30388364
Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis. Torres R, Swift RV, Chim N, Wheatley N, Lan B, Atwood BR, Pujol C, Sankaran B, Bliska JB, Amaro RE, Goulding CW PloS one 21966419 PLoS One 2011 https://www.ncbi.nlm.nih.gov/pubmed/21966419
How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase. Balasubramaniam D, Schiffer J, Parnell J, Mir SP, Amaro RE, Komives EA Biochemistry 25654263 Biochemistry 2015 Mar 3 https://www.ncbi.nlm.nih.gov/pubmed/25654263
Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor. Goldgof GM, Durrant JD, Ottilie S, Vigil E, Allen KE, Gunawan F, Kostylev M, Henderson KA, Yang J, Schenken J, LaMonte GM, Manary MJ, Murao A, Nachon M, Murray R, Prescott M, McNamara CW, Slayman CW, Amaro RE, Suzuki Y, Winzeler EA Scientific reports 27291296 Sci Rep 2016 Jun 13 https://www.ncbi.nlm.nih.gov/pubmed/27291296
Model of the Ankyrin and SOCS Box Protein, ASB9, E3 Ligase Reveals a Mechanism for Dynamic Ubiquitin Transfer. Schiffer JM, Malmstrom RD, Parnell J, Ramirez-Sarmiento C, Reyes J, Amaro RE, Komives EA Structure (London, England : 1993) 27396830 Structure 2016 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/27396830
Full-length p53 tetramer bound to DNA and its quaternary dynamics. Demir Ö, Ieong PU, Amaro RE Oncogene 27641333 Oncogene 2017 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/27641333
Knowledge-Based Methods To Train and Optimize Virtual Screening Ensembles. Swift RV, Jusoh SA, Offutt TL, Li ES, Amaro RE Journal of chemical information and modeling 27097522 J Chem Inf Model 2016 May 23 https://www.ncbi.nlm.nih.gov/pubmed/27097522
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Emerging Computational Methods for the Rational Discovery of Allosteric Drugs. Wagner JR, Lee CT, Durrant JD, Malmstrom RD, Feher VA, Amaro RE Chemical reviews 27074285 Chem Rev 2016 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/27074285
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Equine common variable immunodeficiency: lessons from 100 clinical cases. Julia M, Felippe B Equine veterinary education 39555145 Equine Vet Educ 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/39555145
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Effects of autologous stromal cells and cytokines on differentiation of equine bone marrow-derived progenitor cells. Schwab UE, Tallmadge RL, Matychak MB, Felippe MJB American journal of veterinary research 28945121 Am J Vet Res 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28945121
Developmental expression of B cell molecules in equine lymphoid tissues. Prieto JMB, Tallmadge RL, Felippe MJB Veterinary immunology and immunopathology 28063478 Vet Immunol Immunopathol 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/28063478
Developmental progression of equine immunoglobulin heavy chain variable region diversity. Tallmadge RL, Tseng CT, King RA, Felippe MJ Developmental and comparative immunology 23567345 Dev Comp Immunol 2013 Sep https://www.ncbi.nlm.nih.gov/pubmed/23567345
Diversity of immunoglobulin lambda light chain gene usage over developmental stages in the horse. Tallmadge RL, Tseng CT, Felippe MJ Developmental and comparative immunology 24726757 Dev Comp Immunol 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/24726757
Hematopoiesis in the equine fetal liver suggests immune preparedness. Battista JM, Tallmadge RL, Stokol T, Felippe MJ Immunogenetics 25179685 Immunogenetics 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25179685
Bone marrow transcriptome and epigenome profiles of equine common variable immunodeficiency patients unveil block of B lymphocyte differentiation. Tallmadge RL, Shen L, Tseng CT, Miller SC, Barry J, Felippe MJ Clinical immunology (Orlando, Fla.) 25988861 Clin Immunol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/25988861
The Horse with Recurrent Fevers and Infections: Approach to Common Variable Immunodeficiency. Mullen KR, Felippe MJB The Veterinary clinics of North America. Equine practice 38789347 Vet Clin North Am Equine Pract 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38789347
Optofluidic tunable microlens by manipulating the liquid meniscus using a flared microfluidic structure. Mao X, Stratton ZI, Nawaz AA, Lin SC, Huang TJ Biomicrofluidics 21267439 Biomicrofluidics 2010 Dec 30 https://www.ncbi.nlm.nih.gov/pubmed/21267439
An acoustofluidic micromixer based on oscillating sidewall sharp-edges. Huang PH, Xie Y, Ahmed D, Rufo J, Nama N, Chen Y, Chan CY, Huang TJ Lab on a chip 23896797 Lab Chip 2013 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/23896797
Surface acoustic wave microfluidics. Ding X, Li P, Lin SC, Stratton ZS, Nama N, Guo F, Slotcavage D, Mao X, Shi J, Costanzo F, Huang TJ Lab on a chip 23900527 Lab Chip 2013 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/23900527
A reconfigurable plasmofluidic lens. Zhao C, Liu Y, Zhao Y, Fang N, Huang TJ Nature communications 23929463 Nat Commun 2013 https://www.ncbi.nlm.nih.gov/pubmed/23929463
Multifunctional porous silicon nanopillar arrays: antireflection, superhydrophobicity, photoluminescence, and surface-enhanced Raman scattering. Kiraly B, Yang S, Huang TJ Nanotechnology 23703091 Nanotechnology 2013 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/23703091
Tunable nanowire patterning using standing surface acoustic waves. Chen Y, Ding X, Steven Lin SC, Yang S, Huang PH, Nama N, Zhao Y, Nawaz AA, Guo F, Wang W, Gu Y, Mallouk TE, Huang TJ ACS nano 23540330 ACS Nano 2013 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/23540330
Standing surface acoustic wave based cell coculture. Li S, Guo F, Chen Y, Ding X, Li P, Wang L, Cameron CE, Huang TJ Analytical chemistry 25232648 Anal Chem 2014 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/25232648
Electrochemically Created Highly Surface Roughened Ag Nanoplate Arrays for SERS Biosensing Applications. Yang S, Slotcavage D, Mai JD, Guo F, Li S, Zhao Y, Lei Y, Cameron CE, Huang TJ Journal of materials chemistry. C 25383191 J Mater Chem C Mater 2014 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/25383191
Acoustofluidic chemical waveform generator and switch. Ahmed D, Muddana HS, Lu M, French JB, Ozcelik A, Fang Y, Butler PJ, Benkovic SJ, Manz A, Huang TJ Analytical chemistry 25405550 Anal Chem 2014 Dec 2 https://www.ncbi.nlm.nih.gov/pubmed/25405550
Selectively manipulable acoustic-powered microswimmers. Ahmed D, Lu M, Nourhani A, Lammert PE, Stratton Z, Muddana HS, Crespi VH, Huang TJ Scientific reports 25993314 Sci Rep 2015 May 20 https://www.ncbi.nlm.nih.gov/pubmed/25993314
Molecular plasmonics for biology and nanomedicine. Zheng YB, Kiraly B, Weiss PS, Huang TJ Nanomedicine (London, England) 22630155 Nanomedicine (Lond) 2012 May https://www.ncbi.nlm.nih.gov/pubmed/22630155
Probing circulating tumor cells in microfluidics. Li P, Stratton ZS, Dao M, Ritz J, Huang TJ Lab on a chip 23306378 Lab Chip 2013 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/23306378
Tunable patterning of microparticles and cells using standing surface acoustic waves. Ding X, Shi J, Lin SC, Yazdi S, Kiraly B, Huang TJ Lab on a chip 22648600 Lab Chip 2012 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/22648600
All-Optical Modulation of Localized Surface Plasmon Coupling in a Hybrid System Composed of Photo-Switchable Gratings and Au Nanodisk Arrays. Liu YJ, Zheng YB, Liou J, Chiang IK, Khoo IC, Huang TJ The journal of physical chemistry. C, Nanomaterials and interfaces 21643480 J Phys Chem C Nanomater Interfaces 2011 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/21643480
Scalable manufacturing of plasmonic nanodisk dimers and cusp nanostructures using salting-out quenching method and colloidal lithography. Juluri BK, Chaturvedi N, Hao Q, Lu M, Velegol D, Jensen L, Huang TJ ACS nano 21692473 ACS Nano 2011 Jul 26 https://www.ncbi.nlm.nih.gov/pubmed/21692473
Three-dimensional continuous particle focusing in a microfluidic channel via standing surface acoustic waves (SSAW). Shi J, Yazdi S, Lin SC, Ding X, Chiang IK, Sharp K, Huang TJ Lab on a chip 21709881 Lab Chip 2011 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/21709881
Shape-controlled synthesis of hybrid nanomaterials via three-dimensional hydrodynamic focusing. Lu M, Yang S, Ho YP, Grigsby CL, Leong KW, Huang TJ ACS nano 25268035 ACS Nano 2014 Oct 28 https://www.ncbi.nlm.nih.gov/pubmed/25268035
In situ fabrication of 3D Ag@ZnO nanostructures for microfluidic surface-enhanced Raman scattering systems. Xie Y, Yang S, Mao Z, Li P, Zhao C, Cohick Z, Huang PH, Huang TJ ACS nano 25402207 ACS Nano 2014 Dec 23 https://www.ncbi.nlm.nih.gov/pubmed/25402207
Rare cell isolation and analysis in microfluidics. Chen Y, Li P, Huang PH, Xie Y, Mai JD, Wang L, Nguyen NT, Huang TJ Lab on a chip 24406985 Lab Chip 2014 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/24406985
Lab-on-a-chip technologies for single-molecule studies. Zhao Y, Chen D, Yue H, French JB, Rufo J, Benkovic SJ, Huang TJ Lab on a chip 23670195 Lab Chip 2013 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/23670195
Optofluidic imaging: now and beyond. Zhao Y, Stratton ZS, Guo F, Lapsley MI, Chan CY, Lin SC, Huang TJ Lab on a chip 23138193 Lab Chip 2013 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/23138193
A droplet-based, optofluidic device for high-throughput, quantitative bioanalysis. Guo F, Lapsley MI, Nawaz AA, Zhao Y, Lin SC, Chen Y, Yang S, Zhao XZ, Huang TJ Analytical chemistry 23140515 Anal Chem 2012 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/23140515
Single-shot characterization of enzymatic reaction constants Km and kcat by an acoustic-driven, bubble-based fast micromixer. Xie Y, Ahmed D, Lapsley MI, Lin SC, Nawaz AA, Wang L, Huang TJ Analytical chemistry 22880882 Anal Chem 2012 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/22880882
An acoustofluidic micromixer via bubble inception and cavitation from microchannel sidewalls. Ozcelik A, Ahmed D, Xie Y, Nama N, Qu Z, Nawaz AA, Huang TJ Analytical chemistry 24754496 Anal Chem 2014 May 20 https://www.ncbi.nlm.nih.gov/pubmed/24754496
Exploiting mechanical biomarkers in microfluidics. Mao X, Huang TJ Lab on a chip 22968689 Lab Chip 2012 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/22968689
A single-layer, planar, optofluidic switch powered by acoustically driven, oscillating microbubbles. Huang PH, Ian Lapsley M, Ahmed D, Chen Y, Wang L, Jun Huang T Applied physics letters 23112348 Appl Phys Lett 2012 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/23112348
Standing surface acoustic wave (SSAW) based multichannel cell sorting. Ding X, Lin SC, Lapsley MI, Li S, Guo X, Chan CY, Chiang IK, Wang L, McCoy JP, Huang TJ Lab on a chip 22992833 Lab Chip 2012 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/22992833
High-speed optical humidity sensors based on chiral sculptured thin films. Liu YJ, Shi J, Zhang F, Liang H, Xu J, Lakhtakia A, Fonash SJ, Huang TJ Sensors and actuators. B, Chemical 30739999 Sens Actuators B Chem 2011 Aug https://www.ncbi.nlm.nih.gov/pubmed/30739999
Surface-Enhanced Raman Scattering Study on Graphene-Coated Metallic Nanostructure Substrates. Hao Q, Wang B, Bossard JA, Kiraly B, Zeng Y, Chiang IK, Jensen L, Werner DH, Huang TJ The journal of physical chemistry. C, Nanomaterials and interfaces 24772200 J Phys Chem C Nanomater Interfaces 2012 Apr 5 https://www.ncbi.nlm.nih.gov/pubmed/24772200
Microfluidic synthesis of multifunctional Janus particles for biomedical applications. Yang S, Guo F, Kiraly B, Mao X, Lu M, Leong KW, Huang TJ Lab on a chip 22584998 Lab Chip 2012 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/22584998
Microfluidic opportunities in the field of nutrition. Li S, Kiehne J, Sinoway LI, Cameron CE, Huang TJ Lab on a chip 24056522 Lab Chip 2013 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/24056522
Label-free measurements of reaction kinetics using a droplet-based optofluidic device. Mao Z, Guo F, Xie Y, Zhao Y, Lapsley MI, Wang L, Mai JD, Costanzo F, Huang TJ Journal of laboratory automation 25249275 J Lab Autom 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25249275
Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves. Guo F, Zhou W, Li P, Mao Z, Yennawar NH, French JB, Huang TJ Small (Weinheim an der Bergstrasse, Germany) 25641793 Small 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25641793
Sub-micrometer-precision, three-dimensional (3D) hydrodynamic focusing via "microfluidic drifting". Nawaz AA, Zhang X, Mao X, Rufo J, Lin SC, Guo F, Zhao Y, Lapsley M, Li P, McCoy JP, Levine SJ, Huang TJ Lab on a chip 24287742 Lab Chip 2014 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/24287742
Three-dimensional hydrodynamic focusing method for polyplex synthesis. Lu M, Ho YP, Grigsby CL, Nawaz AA, Leong KW, Huang TJ ACS nano 24341632 ACS Nano 2014 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/24341632
Immunological analyses of whole blood via "microfluidic drifting" based flow cytometric chip. Nawaz AA, Nissly RH, Li P, Chen Y, Guo F, Li S, Shariff YM, Qureshi AN, Wang L, Huang TJ Annals of biomedical engineering 24893596 Ann Biomed Eng 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/24893596
Acoustofluidic relay: sequential trapping and transporting of microparticles via acoustically excited oscillating bubbles. Xie Y, Ahmed D, Lapsley MI, Lu M, Li S, Huang TJ Journal of laboratory automation 23592570 J Lab Autom 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/23592570
Acoustic separation of circulating tumor cells. Li P, Mao Z, Peng Z, Zhou L, Chen Y, Huang PH, Truica CI, Drabick JJ, El-Deiry WS, Dao M, Suresh S, Huang TJ Proceedings of the National Academy of Sciences of the United States of America 25848039 Proc Natl Acad Sci U S A 2015 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/25848039
Holographically formed, acoustically switchable gratings based on polymer-dispersed liquid crystals. Liu YJ, Lu M, Ding X, Leong ES, Lin SC, Shi J, Teng JH, Wang L, Bunning TJ, Huang TJ Journal of laboratory automation 22909448 J Lab Autom 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/22909448
Tunable, pulsatile chemical gradient generation via acoustically driven oscillating bubbles. Ahmed D, Chan CY, Lin SC, Muddana HS, Nama N, Benkovic SJ, Huang TJ Lab on a chip 23254861 Lab Chip 2013 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/23254861
Unconventional microfluidics: expanding the discipline. Nawaz AA, Mao X, Stratton ZS, Huang TJ Lab on a chip 23478651 Lab Chip 2013 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/23478651
Dark-field illumination on zero-mode waveguide/microfluidic hybrid chip reveals T4 replisomal protein interactions. Zhao Y, Chen D, Yue H, Spiering MM, Zhao C, Benkovic SJ, Huang TJ Nano letters 24628474 Nano Lett 2014 https://www.ncbi.nlm.nih.gov/pubmed/24628474
Large-Scale Fabrication of Three-Dimensional Surface Patterns Using Template-Defined Electrochemical Deposition. Yang S, Lapsley MI, Cao B, Zhao C, Zhao Y, Hao Q, Kiraly B, Scott J, Li W, Wang L, Lei Y, Huang TJ Advanced functional materials 31588203 Adv Funct Mater 2013 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/31588203
Microfluidic diagnostics for the developing world. Mao X, Huang TJ Lab on a chip 22406768 Lab Chip 2012 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/22406768
An integrated, multiparametric flow cytometry chip using "microfluidic drifting" based three-dimensional hydrodynamic focusing. Mao X, Nawaz AA, Lin SC, Lapsley MI, Zhao Y, McCoy JP, El-Deiry WS, Huang TJ Biomicrofluidics 22567082 Biomicrofluidics 2012 Jun https://www.ncbi.nlm.nih.gov/pubmed/22567082
Continuous enrichment of low-abundance cell samples using standing surface acoustic waves (SSAW). Chen Y, Li S, Gu Y, Li P, Ding X, Wang L, McCoy JP, Levine SJ, Huang TJ Lab on a chip 24413889 Lab Chip 2014 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/24413889
An on-chip, multichannel droplet sorter using standing surface acoustic waves. Li S, Ding X, Guo F, Chen Y, Lapsley MI, Lin SC, Wang L, McCoy JP, Cameron CE, Huang TJ Analytical chemistry 23647057 Anal Chem 2013 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/23647057
Optoacoustic tweezers: a programmable, localized cell concentrator based on opto-thermally generated, acoustically activated, surface bubbles. Xie Y, Zhao C, Zhao Y, Li S, Rufo J, Yang S, Guo F, Huang TJ Lab on a chip 23511348 Lab Chip 2013 May 7 https://www.ncbi.nlm.nih.gov/pubmed/23511348
Probing cell-cell communication with microfluidic devices. Guo F, French JB, Li P, Zhao H, Chan CY, Fick JR, Benkovic SJ, Huang TJ Lab on a chip 23843092 Lab Chip 2013 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/23843092
Surface acoustic wave (SAW) acoustophoresis: now and beyond. Lin SC, Mao X, Huang TJ Lab on a chip 22781941 Lab Chip 2012 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/22781941
Revisiting lab-on-a-chip technology for drug discovery. Neuži P, Giselbrecht S, Länge K, Huang TJ, Manz A Nature reviews. Drug discovery 22850786 Nat Rev Drug Discov 2012 Aug https://www.ncbi.nlm.nih.gov/pubmed/22850786
Fabrication and characterization of beaded SiC quantum rings with anomalous red spectral shift. Yang S, Kiraly B, Wang WY, Shang S, Cao B, Zeng H, Zhao Y, Li W, Liu ZK, Cai W, Huang TJ Advanced materials (Deerfield Beach, Fla.) 22911493 Adv Mater 2012 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/22911493
On-chip manipulation of single microparticles, cells, and organisms using surface acoustic waves. Ding X, Lin SC, Kiraly B, Yue H, Li S, Chiang IK, Shi J, Benkovic SJ, Huang TJ Proceedings of the National Academy of Sciences of the United States of America 22733731 Proc Natl Acad Sci U S A 2012 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/22733731
Superhydrophobic Surface Enhanced Raman Scattering Sensing using Janus Particle Arrays Realized by Site-Specific Electrochemical Growth. Yang S, Hricko PJ, Huang PH, Li S, Zhao Y, Xie Y, Guo F, Wang L, Huang TJ Journal of materials chemistry. C 24748991 J Mater Chem C Mater 2014 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/24748991
Investigation of acoustic streaming patterns around oscillating sharp edges. Nama N, Huang PH, Huang TJ, Costanzo F Lab on a chip 24903475 Lab Chip 2014 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/24903475
Cell separation using tilted-angle standing surface acoustic waves. Ding X, Peng Z, Lin SC, Geri M, Li S, Li P, Chen Y, Dao M, Suresh S, Huang TJ Proceedings of the National Academy of Sciences of the United States of America 25157150 Proc Natl Acad Sci U S A 2014 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/25157150
A reliable and programmable acoustofluidic pump powered by oscillating sharp-edge structures. Huang PH, Nama N, Mao Z, Li P, Rufo J, Chen Y, Xie Y, Wei CH, Wang L, Huang TJ Lab on a chip 25188786 Lab Chip 2014 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/25188786
Acoustic propulsion of nanorod motors inside living cells. Wang W, Li S, Mair L, Ahmed S, Huang TJ, Mallouk TE Angewandte Chemie (International ed. in English) 24677393 Angew Chem Int Ed Engl 2014 Mar 17 https://www.ncbi.nlm.nih.gov/pubmed/24677393
Accelerating drug discovery via organs-on-chips. Chan CY, Huang PH, Guo F, Ding X, Kapur V, Mai JD, Yuen PK, Huang TJ Lab on a chip 24193241 Lab Chip 2013 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/24193241
Standing surface acoustic wave (SSAW)-based microfluidic cytometer. Chen Y, Nawaz AA, Zhao Y, Huang PH, McCoy JP, Levine SJ, Wang L, Huang TJ Lab on a chip 24406848 Lab Chip 2014 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/24406848
Theory and experiment on particle trapping and manipulation via optothermally generated bubbles. Zhao C, Xie Y, Mao Z, Zhao Y, Rufo J, Yang S, Guo F, Mai JD, Huang TJ Lab on a chip 24276624 Lab Chip 2014 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/24276624
Standing surface acoustic wave (SSAW)-based cell washing. Li S, Ding X, Mao Z, Chen Y, Nama N, Guo F, Li P, Wang L, Cameron CE, Huang TJ Lab on a chip 25372273 Lab Chip 2015 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/25372273
A single-layer, planar, optofluidic Mach-Zehnder interferometer for label-free detection. Lapsley MI, Chiang IK, Zheng YB, Ding X, Mao X, Huang TJ Lab on a chip 21479332 Lab Chip 2011 May 21 https://www.ncbi.nlm.nih.gov/pubmed/21479332
Combining the Masking and Scaffolding Modalities of Colloidal Crystal Templates: Plasmonic Nanoparticle Arrays with Multiple Periodicities. Yang S, Slotcavage D, Mai JD, Liang W, Xie Y, Chen Y, Huang TJ Chemistry of materials : a publication of the American Chemical Society 25620849 Chem Mater 2014 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/25620849
Controlling cell-cell interactions using surface acoustic waves. Guo F, Li P, French JB, Mao Z, Zhao H, Li S, Nama N, Fick JR, Benkovic SJ, Huang TJ Proceedings of the National Academy of Sciences of the United States of America 25535339 Proc Natl Acad Sci U S A 2015 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/25535339
Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms. Chavez MG, Yu W, Biehs B, Harada H, Snead ML, Lee JS, Desai TA, Klein OD Tissue engineering. Part C, Methods 22742471 Tissue Eng Part C Methods 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/22742471
Spry1 and spry2 are essential for development of the temporomandibular joint. Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD Journal of dental research 22328578 J Dent Res 2012 Apr https://www.ncbi.nlm.nih.gov/pubmed/22328578
Stem cell and biomaterials research in dental tissue engineering and regeneration. Horst OV, Chavez MG, Jheon AH, Desai T, Klein OD Dental clinics of North America 22835534 Dent Clin North Am 2012 Jul https://www.ncbi.nlm.nih.gov/pubmed/22835534
From molecules to mastication: the development and evolution of teeth. Jheon AH, Seidel K, Biehs B, Klein OD Wiley interdisciplinary reviews. Developmental biology 24009032 Wiley Interdiscip Rev Dev Biol 2013 Mar-Apr https://www.ncbi.nlm.nih.gov/pubmed/24009032
Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects. Jheon AH, Prochazkova M, Meng B, Wen T, Lim YJ, Naveau A, Espinoza R, Cox TC, Sone ED, Ganss B, Siebel CW, Klein OD Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 26179131 J Bone Miner Res 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/26179131
Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Castillo D, Seidel K, Salcedo E, Ahn C, de Sauvage FJ, Klein OD, Barlow LA Development (Cambridge, England) 24993944 Development 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24993944
On the cutting edge of organ renewal: Identification, regulation, and evolution of incisor stem cells. Kuang-Hsien Hu J, Mushegyan V, Klein OD Genesis (New York, N.Y. : 2000) 24307456 Genesis 2014 Feb https://www.ncbi.nlm.nih.gov/pubmed/24307456
Identification of novel Fgf enhancers and their role in dental evolution. Tapaltsyan V, Charles C, Hu J, Mindell D, Ahituv N, Wilson GM, Black BL, Viriot L, Klein OD Evolution & development 26086993 Evol Dev 2016 Jan-Feb https://www.ncbi.nlm.nih.gov/pubmed/26086993
Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster). Jheon AH, Prochazkova M, Sherman M, Manoli DS, Shah NM, Carbone L, Klein O International journal of oral science 25634121 Int J Oral Sci 2015 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/25634121
Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Charles C, Hovorakova M, Ahn Y, Lyons DB, Marangoni P, Churava S, Biehs B, Jheon A, Lesot H, Balooch G, Krumlauf R, Viriot L, Peterkova R, Klein OD Development (Cambridge, England) 21862563 Development 2011 Sep https://www.ncbi.nlm.nih.gov/pubmed/21862563
FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size. Petersen CI, Jheon AH, Mostowfi P, Charles C, Ching S, Thirumangalathu S, Barlow LA, Klein OD PLoS genetics 21655085 PLoS Genet 2011 Jun https://www.ncbi.nlm.nih.gov/pubmed/21655085
Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. Tian H, Biehs B, Chiu C, Siebel CW, Wu Y, Costa M, de Sauvage FJ, Klein OD Cell reports 25818302 Cell Rep 2015 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/25818302
Replaying evolutionary transitions from the dental fossil record. Harjunmaa E, Seidel K, Häkkinen T, Renvoisé E, Corfe IJ, Kallonen A, Zhang ZQ, Evans AR, Mikkola ML, Salazar-Ciudad I, Klein OD, Jernvall J Nature 25079326 Nature 2014 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/25079326
Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors. Juuri E, Saito K, Ahtiainen L, Seidel K, Tummers M, Hochedlinger K, Klein OD, Thesleff I, Michon F Developmental cell 22819339 Dev Cell 2012 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/22819339
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Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation. Goodwin AF, Tidyman WE, Jheon AH, Sharir A, Zheng X, Charles C, Fagin JA, McMahon M, Diekwisch TG, Ganss B, Rauen KA, Klein OD Human molecular genetics 24057668 Hum Mol Genet 2014 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/24057668
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Tian H, Biehs B, Warming S, Leong KG, Rangell L, Klein OD, de Sauvage FJ Nature 21927002 Nature 2011 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/21927002
Continuously growing rodent molars result from a predictable quantitative evolutionary change over 50 million years. Tapaltsyan V, Eronen JT, Lawing AM, Sharir A, Janis C, Jernvall J, Klein OD Cell reports 25921530 Cell Rep 2015 May 5 https://www.ncbi.nlm.nih.gov/pubmed/25921530
Identification and characterization of small RNAs in Yersinia pestis. Beauregard A, Smith EA, Petrone BL, Singh N, Karch C, McDonough KA, Wade JT RNA biology 23324607 RNA Biol 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23324607
Mapping the Regulatory Network for Salmonella enterica Serovar Typhimurium Invasion. Smith C, Stringer AM, Mao C, Palumbo MJ, Wade JT mBio 27601571 mBio 2016 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/27601571
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Genome-Wide Transcriptional Response to Varying RpoS Levels in Escherichia coli K-12. Wong GT, Bonocora RP, Schep AN, Beeler SM, Lee Fong AJ, Shull LM, Batachari LE, Dillon M, Evans C, Becker CJ, Bush EC, Hardin J, Wade JT, Stoebel DM Journal of bacteriology 28115545 J Bacteriol 2017 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/28115545
Maestro of regulation: Riboswitches orchestrate gene expression at the levels of translation, transcription and mRNA decay. Bastet L, Turcotte P, Wade JT, Lafontaine DA RNA biology 29537923 RNA Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/29537923
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Identification of HilD-regulated genes in Salmonella enterica serovar Typhimurium. Petrone BL, Stringer AM, Wade JT Journal of bacteriology 24375101 J Bacteriol 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24375101
Pervasive transcription: illuminating the dark matter of bacterial transcriptomes. Wade JT, Grainger DC Nature reviews. Microbiology 25069631 Nat Rev Microbiol 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25069631
Genome-Scale Mapping of Escherichia coli σ54 Reveals Widespread, Conserved Intragenic Binding. Bonocora RP, Smith C, Lapierre P, Wade JT PLoS genetics 26425847 PLoS Genet 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26425847
Genome-Wide Mapping of the Escherichia coli PhoB Regulon Reveals Many Transcriptionally Inert, Intragenic Binding Sites. Fitzgerald DM, Stringer AM, Smith C, Lapierre P, Wade JT mBio 37067422 mBio 2023 Jun 27 https://www.ncbi.nlm.nih.gov/pubmed/37067422
Comprehensive mapping of the Escherichia coli flagellar regulatory network. Fitzgerald DM, Bonocora RP, Wade JT PLoS genetics 25275371 PLoS Genet 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25275371
ChIP-seq for genome-scale analysis of bacterial DNA-binding proteins. Bonocora RP, Wade JT Methods in molecular biology (Clifton, N.J.) 25665574 Methods Mol Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25665574
Identification of regulatory RNA in bacterial genomes by genome-scale mapping of transcription start sites. Singh N, Wade JT Methods in molecular biology (Clifton, N.J.) 24318882 Methods Mol Biol 2014 https://www.ncbi.nlm.nih.gov/pubmed/24318882
Identification of regulatory targets for the bacterial Nus factor complex. Baniulyte G, Singh N, Benoit C, Johnson R, Ferguson R, Paramo M, Stringer AM, Scott A, Lapierre P, Wade JT Nature communications 29229908 Nat Commun 2017 Dec 11 https://www.ncbi.nlm.nih.gov/pubmed/29229908
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Coordinated regulation of acid resistance in Escherichia coli. Aquino P, Honda B, Jaini S, Lyubetskaya A, Hosur K, Chiu JG, Ekladious I, Hu D, Jin L, Sayeg MK, Stettner AI, Wang J, Wong BG, Wong WS, Alexander SL, Ba C, Bensussen SI, Bernstein DB, Braff D, Cha S, Cheng DI, Cho JH, Chou K, Chuang J, Gastler DE, Grasso DJ, Greifenberger JS, Guo C, Hawes AK, Israni DV, Jain SR, Kim J, Lei J, Li H, Li D, Li Q, Mancuso CP, Mao N, Masud SF, Meisel CL, Mi J, Nykyforchyn CS, Park M, Peterson HM, Ramirez AK, Reynolds DS, Rim NG, Saffie JC, Su H, Su WR, Su Y, Sun M, Thommes MM, Tu T, Varongchayakul N, Wagner TE, Weinberg BH, Yang R, Yaroslavsky A, Yoon C, Zhao Y, Zollinger AJ, Stringer AM, Foster JW, Wade J, Raman S, Broude N, Wong WW, Galagan JE BMC systems biology 28061857 BMC Syst Biol 2017 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/28061857
The BvgAS Regulon of Bordetella pertussis. Moon K, Bonocora RP, Kim DD, Chen Q, Wade JT, Stibitz S, Hinton DM mBio 29018122 mBio 2017 Oct 10 https://www.ncbi.nlm.nih.gov/pubmed/29018122
Mapping the Escherichia coli DnaA-binding landscape reveals a preference for binding pairs of closely spaced DNA sites. Stringer AM, Fitzgerald DM, Wade JT Microbiology (Reading, England) 39012340 Microbiology (Reading) 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/39012340
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Widespread suppression of intragenic transcription initiation by H-NS. Singh SS, Singh N, Bonocora RP, Fitzgerald DM, Wade JT, Grainger DC Genes & development 24449106 Genes Dev 2014 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/24449106
Regulatory roles of Escherichia coli 5' UTR and ORF-internal RNAs detected by 3' end mapping. Adams PP, Baniulyte G, Esnault C, Chegireddy K, Singh N, Monge M, Dale RK, Storz G, Wade JT eLife 33460557 Elife 2021 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/33460557
The evolutionary impact of intragenic FliA promoters in proteobacteria. Fitzgerald DM, Smith C, Lapierre P, Wade JT Molecular microbiology 29476659 Mol Microbiol 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29476659
MrpJ Directly Regulates Proteus mirabilis Virulence Factors, Including Fimbriae and Type VI Secretion, during Urinary Tract Infection. Debnath I, Stringer AM, Smith SN, Bae E, Mobley HLT, Wade JT, Pearson MM Infection and immunity 30082479 Infect Immun 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30082479
Chemical Inhibition of Kynureninase Reduces Pseudomonas aeruginosa Quorum Sensing and Virulence Factor Expression. Kasper SH, Bonocora RP, Wade JT, Musah RA, Cady NC ACS chemical biology 26785289 ACS Chem Biol 2016 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/26785289
Genome-wide mapping of the Escherichia coli PhoB regulon reveals many transcriptionally inert, intragenic binding sites. Fitzgerald D, Stringer A, Smith C, Lapierre P, Wade JT bioRxiv : the preprint server for biology 36798257 bioRxiv 2023 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/36798257
Probing cell migration in confined environments by plasma lithography. Junkin M, Wong PK Biomaterials 21134692 Biomaterials 2011 Mar https://www.ncbi.nlm.nih.gov/pubmed/21134692
Electrokinetic stringency control in self-assembled monolayer-based biosensors for multiplex urinary tract infection diagnosis. Liu T, Sin ML, Pyne JD, Gau V, Liao JC, Wong PK Nanomedicine : nanotechnology, biology, and medicine 23891989 Nanomedicine 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/23891989
Mechanically induced intercellular calcium communication in confined endothelial structures. Junkin M, Lu Y, Long J, Deymier PA, Hoying JB, Wong PK Biomaterials 23267827 Biomaterials 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23267827
Intelligent Systems and Technology for Integrative and Predictive Medicine: An ACP Approach. Wang FY, Wong PK ACM transactions on intelligent systems and technology 24883228 ACM Trans Intell Syst Technol 2013 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/24883228
Oncogenic KRAS confers chemoresistance by upregulating NRF2. Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD Cancer research 25339352 Cancer Res 2014 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/25339352
Cellular self-organization by autocatalytic alignment feedback. Junkin M, Leung SL, Whitman S, Gregorio CC, Wong PK Journal of cell science 22193956 J Cell Sci 2011 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/22193956
Cellular Architecture Regulates Collective Calcium Signaling and Cell Contractility. Sun J, Hoying JB, Deymier PA, Zhang DD, Wong PK PLoS computational biology 27196735 PLoS Comput Biol 2016 May https://www.ncbi.nlm.nih.gov/pubmed/27196735
Single cell gene expression analysis in injury-induced collective cell migration. Riahi R, Long M, Yang Y, Dean Z, Zhang DD, Slepian MJ, Wong PK Integrative biology : quantitative biosciences from nano to macro 24336811 Integr Biol (Camb) 2014 Feb https://www.ncbi.nlm.nih.gov/pubmed/24336811
A UAV-Mounted Whole Cell Biosensor System for Environmental Monitoring Applications. Lu Y, Macias D, Dean ZS, Kreger NR, Wong PK IEEE transactions on nanobioscience 26584498 IEEE Trans Nanobioscience 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26584498
Advances in wound-healing assays for probing collective cell migration. Riahi R, Yang Y, Zhang DD, Wong PK Journal of laboratory automation 22357609 J Lab Autom 2012 Feb https://www.ncbi.nlm.nih.gov/pubmed/22357609
A nanobiosensor for dynamic single cell analysis during microvascular self-organization. Wang S, Sun J, Zhang DD, Wong PK Nanoscale 27547924 Nanoscale 2016 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/27547924
Calcium wave propagation in networks of endothelial cells: model-based theoretical and experimental study. Long J, Junkin M, Wong PK, Hoying J, Deymier P PLoS computational biology 23300426 PLoS Comput Biol 2012 https://www.ncbi.nlm.nih.gov/pubmed/23300426
Single cell antimicrobial susceptibility testing by confined microchannels and electrokinetic loading. Lu Y, Gao J, Zhang DD, Gau V, Liao JC, Wong PK Analytical chemistry 23445209 Anal Chem 2013 Apr 16 https://www.ncbi.nlm.nih.gov/pubmed/23445209
An AC electrokinetics facilitated biosensor cassette for rapid pathogen identification. Ouyang M, Mohan R, Lu Y, Liu T, Mach KE, Sin ML, McComb M, Joshi J, Gau V, Wong PK, Liao JC The Analyst 23626988 Analyst 2013 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/23626988
Electrokinetic focusing and separation of mammalian cells in conductive biological fluids. Gao J, Riahi R, Sin ML, Zhang S, Wong PK The Analyst 22937529 Analyst 2012 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/22937529
Mapping photothermally induced gene expression in living cells and tissues by nanorod-locked nucleic acid complexes. Riahi R, Wang S, Long M, Li N, Chiou PY, Zhang DD, Wong PK ACS nano 24645754 ACS Nano 2014 Apr 22 https://www.ncbi.nlm.nih.gov/pubmed/24645754
Advances in techniques for probing mechanoregulation of tissue morphogenesis. Sun J, Xiao Y, Wang S, Slepian MJ, Wong PK Journal of laboratory automation 25331491 J Lab Autom 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25331491
Spatiotemporal dynamics of microRNA during epithelial collective cell migration. Dean ZS, Riahi R, Wong PK Biomaterials 25453946 Biomaterials 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25453946
AC Electrokinetics of Physiological Fluids for Biomedical Applications. Lu Y, Liu T, Lamanda AC, Sin ML, Gau V, Liao JC, Wong PK Journal of laboratory automation 25487557 J Lab Autom 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/25487557
Intercellular Tension Negatively Regulates Angiogenic Sprouting of Endothelial Tip Cells via Notch1-Dll4 Signaling. Wang S, Sun J, Xiao Y, Lu Y, Zhang DD, Wong PK Advanced biosystems 30662935 Adv Biosyst 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/30662935
Notch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration. Riahi R, Sun J, Wang S, Long M, Zhang DD, Wong PK Nature communications 25766473 Nat Commun 2015 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/25766473
Long-range electrothermal fluid motion in microfluidic systems. Lu Y, Ren Q, Liu T, Leung SL, Gau V, Liao JC, Chan CL, Wong PK International journal of heat and mass transfer 27127306 Int J Heat Mass Transf 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27127306
Probing Leader Cells in Endothelial Collective Migration by Plasma Lithography Geometric Confinement. Yang Y, Jamilpour N, Yao B, Dean ZS, Riahi R, Wong PK Scientific reports 26936382 Sci Rep 2016 Mar 3 https://www.ncbi.nlm.nih.gov/pubmed/26936382
Probing mechanoregulation of neuronal differentiation by plasma lithography patterned elastomeric substrates. Nam KH, Jamilpour N, Mfoumou E, Wang FY, Zhang DD, Wong PK Scientific reports 25376886 Sci Rep 2014 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/25376886
A microfluidic model for organ-specific extravasation of circulating tumor cells. Riahi R, Yang YL, Kim H, Jiang L, Wong PK, Zohar Y Biomicrofluidics 24803959 Biomicrofluidics 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24803959
Biosensor diagnosis of urinary tract infections: a path to better treatment? Mach KE, Wong PK, Liao JC Trends in pharmacological sciences 21458868 Trends Pharmacol Sci 2011 Jun https://www.ncbi.nlm.nih.gov/pubmed/21458868
Hybrid electrokinetic manipulation in high-conductivity media. Gao J, Sin ML, Liu T, Gau V, Liao JC, Wong PK Lab on a chip 21487576 Lab Chip 2011 May 21 https://www.ncbi.nlm.nih.gov/pubmed/21487576
Plasma lithography surface patterning for creation of cell networks. Junkin M, Leung SL, Yang Y, Lu Y, Volmering J, Wong PK Journal of visualized experiments : JoVE 21694697 J Vis Exp 2011 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/21694697
Single cell nanobiosensors for dynamic gene expression profiling in native tissue microenvironments. Wang S, Riahi R, Li N, Zhang DD, Wong PK Advanced materials (Deerfield Beach, Fla.) 26314800 Adv Mater 2015 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/26314800
Molecular detection of bacterial pathogens using microparticle enhanced double-stranded DNA probes. Riahi R, Mach KE, Mohan R, Liao JC, Wong PK Analytical chemistry 21718053 Anal Chem 2011 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/21718053
In situ electrokinetic enhancement for self-assembled-monolayer-based electrochemical biosensing. Sin ML, Liu T, Pyne JD, Gau V, Liao JC, Wong PK Analytical chemistry 22397486 Anal Chem 2012 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/22397486
Geometric control of capillary architecture via cell-matrix mechanical interactions. Sun J, Jamilpour N, Wang FY, Wong PK Biomaterials 24439400 Biomaterials 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24439400
Detection of mRNA in living cells by double-stranded locked nucleic acid probes. Riahi R, Dean Z, Wu TH, Teitell MA, Chiou PY, Zhang DD, Wong PK The Analyst 23772441 Analyst 2013 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/23772441
A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single cells. Wang S, Xiao Y, Zhang DD, Wong PK Biomaterials 29190498 Biomaterials 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29190498
Collective Cell Migration in 3D Epithelial Wound Healing. Xiao Y, Riahi R, Torab P, Zhang DD, Wong PK ACS nano 30758172 ACS Nano 2019 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/30758172
Statistical metamodeling for revealing synergistic antimicrobial interactions. Chen HC, Gau V, Zhang DD, Liao JC, Wang FY, Wong PK PloS one 21124958 PLoS One 2010 Nov 11 https://www.ncbi.nlm.nih.gov/pubmed/21124958
Rapid antimicrobial susceptibility testing with electrokinetics enhanced biosensors for diagnosis of acute bacterial infections. Liu T, Lu Y, Gau V, Liao JC, Wong PK Annals of biomedical engineering 24889716 Ann Biomed Eng 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/24889716
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A Microfiltration Device for Urogenital Schistosomiasis Diagnostics. Xiao Y, Lu Y, Hsieh M, Liao J, Wong PK PloS one 27124499 PLoS One 2016 https://www.ncbi.nlm.nih.gov/pubmed/27124499
Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality. Pappas CT, Mayfield RM, Henderson C, Jamilpour N, Cover C, Hernandez Z, Hutchinson KR, Chu M, Nam KH, Valdez JM, Wong PK, Granzier HL, Gregorio CC Proceedings of the National Academy of Sciences of the United States of America 26487682 Proc Natl Acad Sci U S A 2015 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/26487682
Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1. Chu M, Novak SM, Cover C, Wang AA, Chinyere IR, Juneman EB, Zarnescu DC, Wong PK, Gregorio CC Circulation 29101288 Circulation 2018 Feb 6 https://www.ncbi.nlm.nih.gov/pubmed/29101288
Intestinal stem cell growth and differentiation on a tubular scaffold with evaluation in small and large animals. Shaffiey SA, Jia H, Keane T, Costello C, Wasserman D, Quidgley M, Dziki J, Badylak S, Sodhi CP, March JC, Hackam DJ Regenerative medicine 26395928 Regen Med 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/26395928
Engineering commensal bacteria for prophylaxis against infection. Goh YL, He H, March JC Current opinion in biotechnology 22459613 Curr Opin Biotechnol 2012 Dec https://www.ncbi.nlm.nih.gov/pubmed/22459613
Engineered commensal bacteria reprogram intestinal cells into glucose-responsive insulin-secreting cells for the treatment of diabetes. Duan FF, Liu JH, March JC Diabetes 25626737 Diabetes 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25626737
3-D intestinal scaffolds for evaluating the therapeutic potential of probiotics. Costello CM, Sorna RM, Goh YL, Cengic I, Jain NK, March JC Molecular pharmaceutics 24798584 Mol Pharm 2014 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/24798584
Secretion of insulinotropic proteins by commensal bacteria: rewiring the gut to treat diabetes. Duan F, Curtis KL, March JC Applied and environmental microbiology 18836005 Appl Environ Microbiol 2008 Dec https://www.ncbi.nlm.nih.gov/pubmed/18836005
Generation of an artificial intestine for the management of short bowel syndrome. Ladd MR, Niño DF, March JC, Sodhi CP, Hackam DJ Current opinion in organ transplantation 26867049 Curr Opin Organ Transplant 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26867049
Salmonella enterica Serovar Typhimurium Increases Functional PD-L1 Synergistically with Gamma Interferon in Intestinal Epithelial Cells via Salmonella Pathogenicity Island 2. Sahler JM, Eade CR, Altier C, March JC Infection and immunity 29440366 Infect Immun 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29440366
Synthetic small intestinal scaffolds for improved studies of intestinal differentiation. Costello CM, Hongpeng J, Shaffiey S, Yu J, Jain NK, Hackam D, March JC Biotechnology and bioengineering 24390638 Biotechnol Bioeng 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24390638
A universal DNA-based protein detection system. Tran TN, Cui J, Hartman MR, Peng S, Funabashi H, Duan F, Yang D, March JC, Lis JT, Cui H, Luo D Journal of the American Chemical Society 23978265 J Am Chem Soc 2013 Sep 25 https://www.ncbi.nlm.nih.gov/pubmed/23978265
SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development. Wei D, Goldfarb D, Song S, Cannon C, Yan F, Sakellariou-Thompson D, Emanuele M, Major MB, Weissman BE, Kuwahara Y Molecular cancer research : MCR 25009291 Mol Cancer Res 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25009291
Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination. Hast BE, Cloer EW, Goldfarb D, Li H, Siesser PF, Yan F, Walter V, Zheng N, Hayes DN, Major MB Cancer research 24322982 Cancer Res 2014 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/24322982
The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase. Onyenwoke RU, Sexton JZ, Yan F, Díaz MC, Forsberg LJ, Major MB, Brenman JE The Biochemical journal 26195823 Biochem J 2015 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/26195823
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Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase. Kim TY, Siesser PF, Rossman KL, Goldfarb D, Mackinnon K, Yan F, Yi X, MacCoss MJ, Moon RT, Der CJ, Major MB Molecular and cellular biology 25332235 Mol Cell Biol 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25332235
FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma. Walker MP, Stopford CM, Cederlund M, Fang F, Jahn C, Rabinowitz AD, Goldfarb D, Graham DM, Yan F, Deal AM, Fedoriw Y, Richards KL, Davis IJ, Weidinger G, Damania B, Major MB Science signaling 25650440 Sci Signal 2015 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/25650440
BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization. Orvis T, Hepperla A, Walter V, Song S, Simon J, Parker J, Wilkerson MD, Desai N, Major MB, Hayes DN, Davis IJ, Weissman B Cancer research 25115300 Cancer Res 2014 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/25115300
USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds. Madan B, Walker MP, Young R, Quick L, Orgel KA, Ryan M, Gupta P, Henrich IC, Ferrer M, Marine S, Roberts BS, Arthur WT, Berndt JD, Oliveira AM, Moon RT, Virshup DM, Chou MM, Major MB Proceedings of the National Academy of Sciences of the United States of America 27162353 Proc Natl Acad Sci U S A 2016 May 24 https://www.ncbi.nlm.nih.gov/pubmed/27162353
FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. Siesser PF, Motolese M, Walker MP, Goldfarb D, Gewain K, Yan F, Kulikauskas RM, Chien AJ, Wordeman L, Major MB Science signaling 22949735 Sci Signal 2012 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/22949735
Dynamics and evolution of β-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening. Shah PK, Walker MP, Sims CE, Major MB, Allbritton NL Integrative biology : quantitative biosciences from nano to macro 24871928 Integr Biol (Camb) 2014 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/24871928
Modulation of Kaposi's sarcoma-associated herpesvirus interleukin-6 function by hypoxia-upregulated protein 1. Giffin L, Yan F, Ben Major M, Damania B Journal of virology 24920810 J Virol 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24920810
Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens. Amberg-Johnson K, Hari SB, Ganesan SM, Lorenzi HA, Sauer RT, Niles JC, Yeh E eLife 28826494 Elife 2017 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/28826494
Direct and specific chemical control of eukaryotic translation with a synthetic RNA-protein interaction. Goldfless SJ, Belmont BJ, de Paz AM, Liu JF, Niles JC Nucleic acids research 22275521 Nucleic Acids Res 2012 May https://www.ncbi.nlm.nih.gov/pubmed/22275521
Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite. Dankwa S, Lim C, Bei AK, Jiang RH, Abshire JR, Patel SD, Goldberg JM, Moreno Y, Kono M, Niles JC, Duraisingh MT Nature communications 27041489 Nat Commun 2016 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/27041489
An integrated platform for genome engineering and gene expression perturbation in Plasmodium falciparum. Nasamu AS, Falla A, Pasaje CFA, Wall BA, Wagner JC, Ganesan SM, Goldfless SJ, Niles JC Scientific reports 33431920 Sci Rep 2021 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/33431920
Versatile control of Plasmodium falciparum gene expression with an inducible protein-RNA interaction. Goldfless SJ, Wagner JC, Niles JC Nature communications 25370483 Nat Commun 2014 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/25370483
Inducible control of subcellular RNA localization using a synthetic protein-RNA aptamer interaction. Belmont BJ, Niles JC PloS one 23056498 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/23056498
Synthetic RNA-protein modules integrated with native translation mechanisms to control gene expression in malaria parasites. Ganesan SM, Falla A, Goldfless SJ, Nasamu AS, Niles JC Nature communications 26925876 Nat Commun 2016 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/26925876
Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum. Wagner JC, Platt RJ, Goldfless SJ, Zhang F, Niles JC Nature methods 25108687 Nat Methods 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25108687
Quantification of labile heme in live malaria parasites using a genetically encoded biosensor. Abshire JR, Rowlands CJ, Ganesan SM, So PT, Niles JC Proceedings of the National Academy of Sciences of the United States of America 28242687 Proc Natl Acad Sci U S A 2017 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/28242687
An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum. Wagner JC, Goldfless SJ, Ganesan SM, Lee MC, Fidock DA, Niles JC Malaria journal 24160265 Malar J 2013 Oct 26 https://www.ncbi.nlm.nih.gov/pubmed/24160265
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik SM, Huet D, Ganesan SM, Huynh MH, Wang T, Nasamu AS, Thiru P, Saeij JPJ, Carruthers VB, Niles JC, Lourido S Cell 27594426 Cell 2016 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/27594426
Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis. Istvan ES, Das S, Bhatnagar S, Beck JR, Owen E, Llinas M, Ganesan SM, Niles JC, Winzeler E, Vaidya AB, Goldberg DE eLife 30888318 Elife 2019 Mar 19 https://www.ncbi.nlm.nih.gov/pubmed/30888318
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Visualizing attack of Escherichia coli by the antimicrobial peptide human defensin 5. Chileveru HR, Lim SA, Chairatana P, Wommack AJ, Chiang IL, Nolan EM Biochemistry 25664683 Biochemistry 2015 Mar 10 https://www.ncbi.nlm.nih.gov/pubmed/25664683
Human calprotectin is an iron-sequestering host-defense protein. Nakashige TG, Zhang B, Krebs C, Nolan EM Nature chemical biology 26302479 Nat Chem Biol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26302479
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Pre-Radiation Therapy Fluorine 18 Fluorodeoxyglucose PET Helps Identify Patients with Esophageal Cancer at High Risk for Radiation Pneumonitis. Castillo R, Pham N, Castillo E, Aso-Gonzalez S, Ansari S, Hobbs B, Palacio D, Skinner H, Guerrero TM Radiology 25584706 Radiology 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25584706
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Inflammation responsive logic gate nanoparticles for the delivery of proteins. Mahmoud EA, Sankaranarayanan J, Morachis JM, Kim G, Almutairi A Bioconjugate chemistry 21688843 Bioconjug Chem 2011 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/21688843
Light-responsive nanoparticle depot to control release of a small molecule angiogenesis inhibitor in the posterior segment of the eye. Huu VA, Luo J, Zhu J, Zhu J, Patel S, Boone A, Mahmoud E, McFearin C, Olejniczak J, de Gracia Lux C, Lux J, Fomina N, Huynh M, Zhang K, Almutairi A Journal of controlled release : official journal of the Controlled Release Society 25571784 J Control Release 2015 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/25571784
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Long-Lasting and Efficient Tumor Imaging Using a High Relaxivity Polysaccharide Nanogel Magnetic Resonance Imaging Contrast Agent. Chan M, Lux J, Nishimura T, Akiyoshi K, Almutairi A Biomacromolecules 26278775 Biomacromolecules 2015 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/26278775
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Developing a low-cost milliliter-scale chemostat array for precise control of cellular growth. Skelding D, Hart SFM, Vidyasagar T, Pozhitkov AE, Shou W Quantitative biology (Beijing, China) 31598380 Quant Biol 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/31598380
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High-throughput quantification of microbial birth and death dynamics using fluorescence microscopy. Hart SFM, Skelding D, Waite AJ, Burton JC, Shou W Quantitative biology (Beijing, China) 31598381 Quant Biol 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/31598381
Strong inter-population cooperation leads to partner intermixing in microbial communities. Momeni B, Brileya KA, Fields MW, Shou W eLife 23359860 Elife 2013 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/23359860
Defectors Can Create Conditions That Rescue Cooperation. Waite AJ, Cannistra C, Shou W PLoS computational biology 26690946 PLoS Comput Biol 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26690946
Pleiotropic mutations can rapidly evolve to directly benefit self and cooperative partner despite unfavorable conditions. Hart SFM, Chen CC, Shou W eLife 33501915 Elife 2021 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/33501915
LINE-1 retrotransposition in the nervous system. Thomas CA, Paquola AC, Muotri AR Annual review of cell and developmental biology 23057747 Annu Rev Cell Dev Biol 2012 https://www.ncbi.nlm.nih.gov/pubmed/23057747
Modeling anorexia nervosa: transcriptional insights from human iPSC-derived neurons. Negraes PD, Cugola FR, Herai RH, Trujillo CA, Cristino AS, Chailangkarn T, Muotri AR, Duvvuri V Translational psychiatry 28291261 Transl Psychiatry 2017 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/28291261
Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. Kim JJ, Savas JN, Miller MT, Hu X, Carromeu C, Lavallée-Adam M, Freitas BCG, Muotri AR, Yates JR 3rd, Ghosh A PloS one 30789962 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/30789962
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria K, Beltrao-Braga P, Trujillo CA, Mendes APD, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand K, Pierce K, Eichenfield L, Pramparo T, Eyler L, Barnes CC, Courchesne E, Geschwind DH, Gage FH, Wynshaw-Boris A, Muotri AR Molecular psychiatry 27378147 Mol Psychiatry 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/27378147
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation. Thomas CA, Tejwani L, Trujillo CA, Negraes PD, Herai RH, Mesci P, Macia A, Crow YJ, Muotri AR Cell stem cell 28803918 Cell Stem Cell 2017 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/28803918
Severe Hypoxia: Consequences to Neural Stem Cells and Neurons. Felfly H, Zambon AC, Xue J, Muotri A, Zhou D, Snyder EY, Haddad GG Journal of neurology research 24348887 J Neurol Res 2011 https://www.ncbi.nlm.nih.gov/pubmed/24348887
Evolution, development, and plasticity of the human brain: from molecules to bones. Hrvoj-Mihic B, Bienvenu T, Stefanacci L, Muotri AR, Semendeferi K Frontiers in human neuroscience 24194709 Front Hum Neurosci 2013 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/24194709
Altered neuronal network and rescue in a human MECP2 duplication model. Nageshappa S, Carromeu C, Trujillo CA, Mesci P, Espuny-Camacho I, Pasciuto E, Vanderhaeghen P, Verfaillie CM, Raitano S, Kumar A, Carvalho CM, Bagni C, Ramocki MB, Araujo BH, Torres LB, Lupski JR, Van Esch H, Muotri AR Molecular psychiatry 26347316 Mol Psychiatry 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26347316
Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome. Andrade LN, Nathanson JL, Yeo GW, Menck CF, Muotri AR Human molecular genetics 22661500 Hum Mol Genet 2012 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/22661500
Stem cells and modeling of autism spectrum disorders. Freitas BC, Trujillo CA, Carromeu C, Yusupova M, Herai RH, Muotri AR Experimental neurology 23036599 Exp Neurol 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/23036599
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR Molecular psychiatry 25385366 Mol Psychiatry 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/25385366
Micro RNA detection in long-term fixed tissue of cortical glutamatergic pyramidal neurons after targeted laser-capture neuroanatomical microdissection. Herai RR, Stefanacci L, Hrvoj-Mihic B, Chailangkarn T, Hanson K, Semendeferi K, Muotri AR Journal of neuroscience methods 24992573 J Neurosci Methods 2014 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/24992573
Altered iPSC-derived neurons' sodium channel properties in subjects with Monge's disease. Zhao HW, Gu XQ, Chailangkarn T, Perkins G, Callacondo D, Appenzeller O, Poulsen O, Zhou D, Muotri AR, Haddad GG Neuroscience 25559931 Neuroscience 2015 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/25559931
The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment. Acab A, Muotri AR Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 25851569 Neurotherapeutics 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/25851569
Brains, genes, and primates. Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, Ringach D, Sejnowski TJ, Silva AC, Strick PL, Wu J, Zhang F Neuron 25950631 Neuron 2015 May 6 https://www.ncbi.nlm.nih.gov/pubmed/25950631
Modeling neurodevelopmental disorders using human neurons. Chailangkarn T, Acab A, Muotri AR Current opinion in neurobiology 22717528 Curr Opin Neurobiol 2012 Oct https://www.ncbi.nlm.nih.gov/pubmed/22717528
Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. Tang X, Zhou L, Wagner AM, Marchetto MC, Muotri AR, Gage FH, Chen G Stem cell research 23759711 Stem Cell Res 2013 Sep https://www.ncbi.nlm.nih.gov/pubmed/23759711
Modeling autism spectrum disorders with human neurons. Beltrão-Braga PC, Muotri AR Brain research 26854137 Brain Res 2017 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/26854137
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids. Trujillo CA, Adams JW, Negraes PD, Carromeu C, Tejwani L, Acab A, Tsuda B, Thomas CA, Sodhi N, Fichter KM, Romero S, Zanella F, Sejnowski TJ, Ulrich H, Muotri AR EMBO molecular medicine 33501759 EMBO Mol Med 2021 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/33501759
Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment. Adams JW, Vinokur A, de Souza JS, Austria C, Guerra BS, Herai RH, Wahlin KJ, Muotri AR Cell reports 38416640 Cell Rep 2024 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/38416640
Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. Cortes CJ, Miranda HC, Frankowski H, Batlevi Y, Young JE, Le A, Ivanov N, Sopher BL, Carromeu C, Muotri AR, Garden GA, La Spada AR Nature neuroscience 25108912 Nat Neurosci 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25108912
Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus. Lovatel GA, Elsner VR, Bertoldi K, Vanzella C, Moysés Fdos S, Vizuete A, Spindler C, Cechinel LR, Netto CA, Muotri AR, Siqueira IR Neurobiology of learning and memory 23357282 Neurobiol Learn Mem 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23357282
Novel tools, classic techniques: evolutionary studies using primate pluripotent stem cells. Hrvoj-Mihic B, Marchetto MC, Gage FH, Semendeferi K, Muotri AR Biological psychiatry 24041506 Biol Psychiatry 2014 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/24041506
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR Cell 21074045 Cell 2010 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/21074045
KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. Tang X, Kim J, Zhou L, Wengert E, Zhang L, Wu Z, Carromeu C, Muotri AR, Marchetto MC, Gage FH, Chen G Proceedings of the National Academy of Sciences of the United States of America 26733678 Proc Natl Acad Sci U S A 2016 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/26733678
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, Fredlender C, Randolph-Moore L, Kshirsagar R, Xenitopoulos R, Chou G, Hah N, Muotri AR, Padmanabhan K, Semendeferi K, Gage FH eLife 30730291 Elife 2019 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/30730291
The Human Model: Changing Focus on Autism Research. Muotri AR Biological psychiatry 25861701 Biol Psychiatry 2016 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/25861701
L1 Retrotransposition in Neural Progenitor Cells. Muotri AR Methods in molecular biology (Clifton, N.J.) 26895053 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/26895053
Exercise induces age-dependent changes on epigenetic parameters in rat hippocampus: a preliminary study. Elsner VR, Lovatel GA, Moysés F, Bertoldi K, Spindler C, Cechinel LR, Muotri AR, Siqueira IR Experimental gerontology 23201423 Exp Gerontol 2013 Feb https://www.ncbi.nlm.nih.gov/pubmed/23201423
Kinin-B2 receptor activity determines the differentiation fate of neural stem cells. Trujillo CA, Negraes PD, Schwindt TT, Lameu C, Carromeu C, Muotri AR, Pesquero JB, Cerqueira DM, Pillat MM, de Souza HD, Turaça LT, Abreu JG, Ulrich H The Journal of biological chemistry 23132855 J Biol Chem 2012 Dec 28 https://www.ncbi.nlm.nih.gov/pubmed/23132855
Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH Proceedings of the National Academy of Sciences of the United States of America 22159035 Proc Natl Acad Sci U S A 2011 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/22159035
Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony. Vessoni AT, Herai RH, Karpiak JV, Leal AM, Trujillo CA, Quinet A, Agnez Lima LF, Menck CF, Muotri AR Human molecular genetics 26755826 Hum Mol Genet 2016 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/26755826
Systematic optimization of human pluripotent stem cells media using Design of Experiments. Marinho PA, Chailangkarn T, Muotri AR Scientific reports 25940691 Sci Rep 2015 May 5 https://www.ncbi.nlm.nih.gov/pubmed/25940691
L1 retrotransposition in neurons is modulated by MeCP2. Muotri AR, Marchetto MC, Coufal NG, Oefner R, Yeo G, Nakashima K, Gage FH Nature 21085180 Nature 2010 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/21085180
LINE-1: creators of neuronal diversity. Thomas CA, Muotri AR Frontiers in bioscience (Elite edition) 22201983 Front Biosci (Elite Ed) 2012 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/22201983
A human neurodevelopmental model for Williams syndrome. Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR Nature 27509850 Nature 2016 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/27509850
Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation. Pillat MM, Lameu C, Trujillo CA, Glaser T, Cappellari AR, Negraes PD, Battastini AM, Schwindt TT, Muotri AR, Ulrich H Journal of cell science 27528403 J Cell Sci 2016 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/27528403
Characterizing complex structural variation in germline and somatic genomes. Quinlan AR, Hall IM Trends in genetics : TIG 22094265 Trends Genet 2012 Jan https://www.ncbi.nlm.nih.gov/pubmed/22094265
Defining the DNA uptake specificity of naturally competent Haemophilus influenzae cells. Mell JC, Hall IM, Redfield RJ Nucleic acids research 22753031 Nucleic Acids Res 2012 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/22753031
YAHA: fast and flexible long-read alignment with optimal breakpoint detection. Faust GG, Hall IM Bioinformatics (Oxford, England) 22829624 Bioinformatics 2012 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/22829624
Mosaic copy number variation in human neurons. McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch JR, Hall IM, Gage FH Science (New York, N.Y.) 24179226 Science 2013 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/24179226
Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome. Quinlan AR, Clark RA, Sokolova S, Leibowitz ML, Zhang Y, Hurles ME, Mell JC, Hall IM Genome research 20308636 Genome Res 2010 May https://www.ncbi.nlm.nih.gov/pubmed/20308636
Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming. Quinlan AR, Boland MJ, Leibowitz ML, Shumilina S, Pehrson SM, Baldwin KK, Hall IM Cell stem cell 21982236 Cell Stem Cell 2011 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/21982236
SAMBLASTER: fast duplicate marking and structural variant read extraction. Faust GG, Hall IM Bioinformatics (Oxford, England) 24812344 Bioinformatics 2014 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/24812344
Identification of Drivers of Aneuploidy in Breast Tumors. Pfister K, Pipka JL, Chiang C, Liu Y, Clark RA, Keller R, Skoglund P, Guertin MJ, Hall IM, Stukenberg PT Cell reports 29847804 Cell Rep 2018 May 29 https://www.ncbi.nlm.nih.gov/pubmed/29847804
BEDTools: a flexible suite of utilities for comparing genomic features. Quinlan AR, Hall IM Bioinformatics (Oxford, England) 20110278 Bioinformatics 2010 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/20110278
LUMPY: a probabilistic framework for structural variant discovery. Layer RM, Chiang C, Quinlan AR, Hall IM Genome biology 24970577 Genome Biol 2014 Jun 26 https://www.ncbi.nlm.nih.gov/pubmed/24970577
Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms. Malhotra A, Lindberg M, Faust GG, Leibowitz ML, Clark RA, Layer RM, Quinlan AR, Hall IM Genome research 23410887 Genome Res 2013 May https://www.ncbi.nlm.nih.gov/pubmed/23410887
Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations. Malhotra A, Wang Y, Waters J, Chen K, Meric-Bernstam F, Hall IM, Navin NE Genome medicine 25729435 Genome Med 2015 https://www.ncbi.nlm.nih.gov/pubmed/25729435
SpeedSeq: ultra-fast personal genome analysis and interpretation. Chiang C, Layer RM, Faust GG, Lindberg MR, Rose DB, Garrison EP, Marth GT, Quinlan AR, Hall IM Nature methods 26258291 Nat Methods 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26258291
The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning. Hazen JL, Faust GG, Rodriguez AR, Ferguson WC, Shumilina S, Clark RA, Boland MJ, Martin G, Chubukov P, Tsunemoto RK, Torkamani A, Kupriyanov S, Hall IM, Baldwin KK Neuron 26948891 Neuron 2016 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/26948891
Noninvasive determination of 2-[18F]-fluoroisonicotinic acid hydrazide pharmacokinetics by positron emission tomography in Mycobacterium tuberculosis-infected mice. Weinstein EA, Liu L, Ordonez AA, Wang H, Hooker JM, Tonge PJ, Jain SK Antimicrobial agents and chemotherapy 23006755 Antimicrob Agents Chemother 2012 Dec https://www.ncbi.nlm.nih.gov/pubmed/23006755
Role of Mycobacterium tuberculosis pknD in the pathogenesis of central nervous system tuberculosis. Be NA, Bishai WR, Jain SK BMC microbiology 22243650 BMC Microbiol 2012 Jan 13 https://www.ncbi.nlm.nih.gov/pubmed/22243650
Template Registration with Missing Parts: Application to the Segmentation of M. Tuberculosis Infected Lungs. Vidal C, Hewitt J, Davis S, Younes L, Jain S, Jedynak B Proceedings. IEEE International Symposium on Biomedical Imaging 26146531 Proc IEEE Int Symp Biomed Imaging 2009 Jun-Jul https://www.ncbi.nlm.nih.gov/pubmed/26146531
Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation. Kübler A, Luna B, Larsson C, Ammerman NC, Andrade BB, Orandle M, Bock KW, Xu Z, Bagci U, Mollura DJ, Marshall J, Burns J, Winglee K, Ahidjo BA, Cheung LS, Klunk M, Jain SK, Kumar NP, Babu S, Sher A, Friedland JS, Elkington PT, Bishai WR The Journal of pathology 25186281 J Pathol 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25186281
Efficient ribcage segmentation from CT scans using shape features. Xu Z, Bagci U, Jonsson C, Jain S, Mollura DJ Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 25570597 Annu Int Conf IEEE Eng Med Biol Soc 2014 https://www.ncbi.nlm.nih.gov/pubmed/25570597
Accurate and efficient separation of left and right lungs from 3D CT scans: A generic hysteresis approach. Ziyue Xu, Bagci U, Jonsson C, Jain S, Mollura DJ Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 25571373 Annu Int Conf IEEE Eng Med Biol Soc 2014 https://www.ncbi.nlm.nih.gov/pubmed/25571373
Microglia activation in a pediatric rabbit model of tuberculous meningitis. Tucker EW, Pokkali S, Zhang Z, DeMarco VP, Klunk M, Smith ES, Ordonez AA, Penet MF, Bhujwalla Z, Jain SK, Kannan S Disease models & mechanisms 27935825 Dis Model Mech 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27935825
Modifiable risk factors associated with tuberculosis disease in children in Pune, India. Jubulis J, Kinikar A, Ithape M, Khandave M, Dixit S, Hotalkar S, Kulkarni V, Mave V, Gupte N, Kagal A, Jain S, Bharadwaj R, Gupta A The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 24429313 Int J Tuberc Lung Dis 2014 Feb https://www.ncbi.nlm.nih.gov/pubmed/24429313
Novel vaccine strategies against tuberculosis: a road less travelled. Pokkali S, Jain S Expert review of vaccines 24195477 Expert Rev Vaccines 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/24195477
Pediatric tuberculosis in young children in India: a prospective study. Jain SK, Ordonez A, Kinikar A, Gupte N, Thakar M, Mave V, Jubulis J, Dharmshale S, Desai S, Hatolkar S, Kagal A, Lalvani A, Gupta A, Bharadwaj R BioMed research international 24386640 Biomed Res Int 2013 https://www.ncbi.nlm.nih.gov/pubmed/24386640
Imaging Chronic Tuberculous Lesions Using Sodium [(18)F]Fluoride Positron Emission Tomography in Mice. Ordonez AA, DeMarco VP, Klunk MH, Pokkali S, Jain SK Molecular imaging and biology 25750032 Mol Imaging Biol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/25750032
Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology. Ordonez AA, Pokkali S, Sanchez-Bautista J, Klunk MH, Urbanowski ME, Kübler A, Bishai WR, Elkington PT, Jain SK The Journal of infectious diseases 29920600 J Infect Dis 2019 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/29920600
Incorporating User Input in Template-Based Segmentation. Vidal C, Beggs D, Younes L, Jain SK, Jedynak B Proceedings. IEEE International Symposium on Biomedical Imaging 26146532 Proc IEEE Int Symp Biomed Imaging 2011 Mar-Apr https://www.ncbi.nlm.nih.gov/pubmed/26146532
White paper report of the 2011 RAD-AID Conference on International Radiology for Developing Countries: integrating multidisciplinary strategies for imaging services in the developing world. Everton KL, Mazal J, Mollura DJ, RAD-AID Conference Writing Group Journal of the American College of Radiology : JACR 22748790 J Am Coll Radiol 2012 Jul https://www.ncbi.nlm.nih.gov/pubmed/22748790
Strain-dependent CNS dissemination in guinea pigs after Mycobacterium tuberculosis aerosol challenge. Be NA, Klinkenberg LG, Bishai WR, Karakousis PC, Jain SK Tuberculosis (Edinburgh, Scotland) 21831713 Tuberculosis (Edinb) 2011 Sep https://www.ncbi.nlm.nih.gov/pubmed/21831713
Imaging Enterobacteriaceae infection in vivo with 18F-fluorodeoxysorbitol positron emission tomography. Weinstein EA, Ordonez AA, DeMarco VP, Murawski AM, Pokkali S, MacDonald EM, Klunk M, Mease RC, Pomper MG, Jain SK Science translational medicine 25338757 Sci Transl Med 2014 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/25338757
Segmentation of PET images for computer-aided functional quantification of tuberculosis in small animal models. Foster B, Bagci U, Ziyue Xu, Dey B, Luna B, Bishai W, Jain S, Mollura DJ IEEE transactions on bio-medical engineering 24235292 IEEE Trans Biomed Eng 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24235292
Extensively drug-resistant tuberculosis in a young child after travel to India. Salazar-Austin N, Ordonez AA, Hsu AJ, Benson JE, Mahesh M, Menachery E, Razeq JH, Salfinger M, Starke JR, Milstone AM, Parrish N, Nuermberger EL, Jain SK The Lancet. Infectious diseases 26607130 Lancet Infect Dis 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26607130
The biodistribution of 5-[18F]fluoropyrazinamide in Mycobacterium tuberculosis-infected mice determined by positron emission tomography. Zhang Z, Ordonez AA, Smith-Jones P, Wang H, Gogarty KR, Daryaee F, Bambarger LE, Chang YS, Jain SK, Tonge PJ PloS one 28151985 PLoS One 2017 https://www.ncbi.nlm.nih.gov/pubmed/28151985
In vivo prediction of tuberculosis-associated cavity formation in rabbits. Luna B, Kubler A, Larsson C, Foster B, Bagci U, Mollura DJ, Jain SK, Bishai WR The Journal of infectious diseases 25117755 J Infect Dis 2015 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/25117755
Noninvasive molecular imaging of tuberculosis-associated inflammation with radioiodinated DPA-713. Foss CA, Harper JS, Wang H, Pomper MG, Jain SK The Journal of infectious diseases 23901092 J Infect Dis 2013 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/23901092
Novel interferon-gamma assays for diagnosing tuberculosis in young children in India. Shaikh N, Gupte A, Dharmshale S, Pokkali S, Thakar M, Upadhye VJ, Ordonez AA, Kinikar A, Gupte N, Mave V, Kagal A, Gupta A, Lalvani A, Paranjpe R, Bharadwaj R, Jain SK The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 28284256 Int J Tuberc Lung Dis 2017 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/28284256
The Promise of Molecular Imaging in the Study and Treatment of Infectious Diseases. Jain SK Molecular imaging and biology 28155078 Mol Imaging Biol 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28155078
Nuclear imaging: a powerful novel approach for tuberculosis. Johnson DH, Via LE, Kim P, Laddy D, Lau CY, Weinstein EA, Jain S Nuclear medicine and biology 25195017 Nucl Med Biol 2014 Nov-Dec https://www.ncbi.nlm.nih.gov/pubmed/25195017
Determination of [11C]rifampin pharmacokinetics within Mycobacterium tuberculosis-infected mice by using dynamic positron emission tomography bioimaging. DeMarco VP, Ordonez AA, Klunk M, Prideaux B, Wang H, Zhuo Z, Tonge PJ, Dannals RF, Holt DP, Lee CK, Weinstein EA, Dartois V, Dooley KE, Jain SK Antimicrobial agents and chemotherapy 26169396 Antimicrob Agents Chemother 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26169396
A Systematic Approach for Developing Bacteria-Specific Imaging Tracers. Ordonez AA, Weinstein EA, Bambarger LE, Saini V, Chang YS, DeMarco VP, Klunk MH, Urbanowski ME, Moulton KL, Murawski AM, Pokkali S, Kalinda AS, Jain SK Journal of nuclear medicine : official publication, Society of Nuclear Medicine 27635025 J Nucl Med 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27635025
Vaccination with recombinant Mycobacterium tuberculosis PknD attenuates bacterial dissemination to the brain in guinea pigs. Skerry C, Pokkali S, Pinn M, Be NA, Harper J, Karakousis PC, Jain SK PloS one 23776655 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23776655
A computational pipeline for quantification of pulmonary infections in small animal models using serial PET-CT imaging. Bagci U, Foster B, Miller-Jaster K, Luna B, Dey B, Bishai WR, Jonsson CB, Jain S, Mollura DJ EJNMMI research 23879987 EJNMMI Res 2013 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/23879987
Novel adjunctive therapies for the treatment of tuberculosis. Ordonez AA, Maiga M, Gupta S, Weinstein EA, Bishai WR, Jain SK Current molecular medicine 24236454 Curr Mol Med 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24236454
Imaging the evolution of reactivation pulmonary tuberculosis in mice using 18F-FDG PET. Murawski AM, Gurbani S, Harper JS, Klunk M, Younes L, Jain SK, Jedynak BM Journal of nuclear medicine : official publication, Society of Nuclear Medicine 25082854 J Nucl Med 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25082854
Characterization of a novel necrotic granuloma model of latent tuberculosis infection and reactivation in mice. Dutta NK, Illei PB, Jain SK, Karakousis PC The American journal of pathology 24815353 Am J Pathol 2014 Jul https://www.ncbi.nlm.nih.gov/pubmed/24815353
Pathogenesis of central nervous system tuberculosis. Be NA, Kim KS, Bishai WR, Jain SK Current molecular medicine 19275620 Curr Mol Med 2009 Mar https://www.ncbi.nlm.nih.gov/pubmed/19275620
Adjunctive TNF inhibition with standard treatment enhances bacterial clearance in a murine model of necrotic TB granulomas. Skerry C, Harper J, Klunk M, Bishai WR, Jain SK PloS one 22761866 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/22761866
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Oral-Only Linezolid-Rifampin Is Highly Effective Compared with Other Antibiotics for Periprosthetic Joint Infection: Study of a Mouse Model. Thompson JM, Saini V, Ashbaugh AG, Miller RJ, Ordonez AA, Ortines RV, Wang Y, Sterling RS, Jain SK, Miller LS The Journal of bone and joint surgery. American volume 28419033 J Bone Joint Surg Am 2017 Apr 19 https://www.ncbi.nlm.nih.gov/pubmed/28419033
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Protein-engineered hydrogel encapsulation for 3-D culture of murine cochlea. Chang DT, Chai R, DiMarco R, Heilshorn SC, Cheng AG Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 25111520 Otol Neurotol 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25111520
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One-pot Synthesis of Elastin-like Polypeptide Hydrogels with Grafted VEGF-Mimetic Peptides. Cai L, Dinh CB, Heilshorn SC Biomaterials science 24729868 Biomater Sci 2014 May 1 https://www.ncbi.nlm.nih.gov/pubmed/24729868
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Matrix RGD ligand density and L1CAM-mediated Schwann cell interactions synergistically enhance neurite outgrowth. Romano NH, Madl CM, Heilshorn SC Acta biomaterialia 25308870 Acta Biomater 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25308870
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Protein-engineered injectable hydrogel to improve retention of transplanted adipose-derived stem cells. Parisi-Amon A, Mulyasasmita W, Chung C, Heilshorn SC Advanced healthcare materials 23184882 Adv Healthc Mater 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23184882
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Photoreactive elastin-like proteins for use as versatile bioactive materials and surface coatings. Raphel J, Parisi-Amon A, Heilshorn S Journal of materials chemistry 23015764 J Mater Chem 2012 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/23015764
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Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers. Aguado BA, Mulyasasmita W, Su J, Lampe KJ, Heilshorn SC Tissue engineering. Part A 22011213 Tissue Eng Part A 2012 Apr https://www.ncbi.nlm.nih.gov/pubmed/22011213
Microfluidic gradients reveal enhanced neurite outgrowth but impaired guidance within 3D matrices with high integrin ligand densities. Romano NH, Lampe KJ, Xu H, Ferreira MM, Heilshorn SC Small (Weinheim an der Bergstrasse, Germany) 25315156 Small 2015 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/25315156
Robust Iterative Stimulation with Self-Antigens Overcomes CD8(+) T Cell Tolerance to Self- and Tumor Antigens. Nelson CE, Thompson EA, Quarnstrom CF, Fraser KA, Seelig DM, Bhela S, Burbach BJ, Masopust D, Vezys V Cell reports 31533033 Cell Rep 2019 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/31533033
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The use of contact heat evoked potential stimulator (CHEPS) in magnetoencephalography for pain research. Gopalakrishnan R, Machado AG, Burgess RC, Mosher JC Journal of neuroscience methods 23994044 J Neurosci Methods 2013 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/23994044
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The molecular origins of chiral growth in walled cells. Huang KC, Ehrhardt DW, Shaevitz JW Current opinion in microbiology 23194654 Curr Opin Microbiol 2012 Dec https://www.ncbi.nlm.nih.gov/pubmed/23194654
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Posttranslational acetylation of α-tubulin constrains protofilament number in native microtubules. Cueva JG, Hsin J, Huang KC, Goodman MB Current biology : CB 22658592 Curr Biol 2012 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/22658592
Interplay between the localization and kinetics of phosphorylation in flagellar pole development of the bacterium Caulobacter crescentus. Tropini C, Huang KC PLoS computational biology 22876167 PLoS Comput Biol 2012 https://www.ncbi.nlm.nih.gov/pubmed/22876167
Mechanics of membrane bulging during cell-wall disruption in gram-negative bacteria. Daly KE, Huang KC, Wingreen NS, Mukhopadhyay R Physical review. E, Statistical, nonlinear, and soft matter physics 21599215 Phys Rev E Stat Nonlin Soft Matter Phys 2011 Apr https://www.ncbi.nlm.nih.gov/pubmed/21599215
Physics of Intracellular Organization in Bacteria. Wingreen NS, Huang KC Annual review of microbiology 26488278 Annu Rev Microbiol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26488278
Bacterial division. Mechanical crack propagation drives millisecond daughter cell separation in Staphylococcus aureus. Zhou X, Halladin DK, Rojas ER, Koslover EF, Lee TK, Huang KC, Theriot JA Science (New York, N.Y.) 25931560 Science 2015 May 1 https://www.ncbi.nlm.nih.gov/pubmed/25931560
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Strain Library Imaging Protocol for high-throughput, automated single-cell microscopy of large bacterial collections arrayed on multiwell plates. Shi H, Colavin A, Lee TK, Huang KC Nature protocols 28125106 Nat Protoc 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/28125106
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A dynamically assembled cell wall synthesis machinery buffers cell growth. Lee TK, Tropini C, Hsin J, Desmarais SM, Ursell TS, Gong E, Gitai Z, Monds RD, Huang KC Proceedings of the National Academy of Sciences of the United States of America 24550500 Proc Natl Acad Sci U S A 2014 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/24550500
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Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants. Cornelissen L, Kim SE, Purdon PL, Brown EN, Berde CB eLife 26102526 Elife 2015 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/26102526
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An enhanced cerebral recovery index for coma prognostication following cardiac arrest. Ghassemi MM, Amorim E, Pati SB, Mark RG, Brown EN, Purdon PL, Westover MB Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 26736317 Annu Int Conf IEEE Eng Med Biol Soc 2015 https://www.ncbi.nlm.nih.gov/pubmed/26736317
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A transient cortical state with sleep-like sensory responses precedes emergence from general anesthesia in humans. Lewis LD, Piantoni G, Peterfreund RA, Eskandar EN, Harrell PG, Akeju O, Aglio LS, Cash SS, Brown EN, Mukamel EA, Purdon PL eLife 30095069 Elife 2018 Aug 10 https://www.ncbi.nlm.nih.gov/pubmed/30095069
Real-time segmentation of burst suppression patterns in critical care EEG monitoring. Brandon Westover M, Shafi MM, Ching S, Chemali JJ, Purdon PL, Cash SS, Brown EN Journal of neuroscience methods 23891828 J Neurosci Methods 2013 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/23891828
A spatiotemporal dynamic distributed solution to the MEG inverse problem. Lamus C, Hämäläinen MS, Temereanca S, Brown EN, Purdon PL NeuroImage 22155043 Neuroimage 2012 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/22155043
Bayesian analysis of trinomial data in behavioral experiments and its application to human studies of general anesthesia. Wong KF, Smith AC, Pierce ET, Harrell PG, Walsh JL, Salazar AF, Tavares CL, Cimenser A, Prerau MJ, Mukamel EA, Sampson A, Purdon PL, Brown EN Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 22255388 Annu Int Conf IEEE Eng Med Biol Soc 2011 https://www.ncbi.nlm.nih.gov/pubmed/22255388
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Cost-effective and compact wide-field fluorescent imaging on a cell-phone. Zhu H, Yaglidere O, Su TW, Tseng D, Ozcan A Lab on a chip 21063582 Lab Chip 2011 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/21063582
Killing of targets by CD8 T cells in the mouse spleen follows the law of mass action. Ganusov VV, Barber DL, De Boer RJ PloS one 21283669 PLoS One 2011 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/21283669
Wide-field lensless fluorescent microscopy using a tapered fiber-optic faceplate on a chip. Coskun AF, Sencan I, Su TW, Ozcan A The Analyst 21283900 Analyst 2011 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/21283900
Compact and light-weight automated semen analysis platform using lensfree on-chip microscopy. Su TW, Erlinger A, Tseng D, Ozcan A Analytical chemistry 20836503 Anal Chem 2010 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/20836503
A personalized food allergen testing platform on a cellphone. Coskun AF, Wong J, Khodadadi D, Nagi R, Tey A, Ozcan A Lab on a chip 23254910 Lab Chip 2013 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/23254910
Lens-free computational imaging of capillary morphogenesis within three-dimensional substrates. Weidling J, Isikman SO, Greenbaum A, Ozcan A, Botvinick E Journal of biomedical optics 23235893 J Biomed Opt 2012 Dec https://www.ncbi.nlm.nih.gov/pubmed/23235893
Quantum dot enabled detection of Escherichia coli using a cell-phone. Zhu H, Sikora U, Ozcan A The Analyst 22396952 Analyst 2012 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/22396952
Giga-pixel lensfree holographic microscopy and tomography using color image sensors. Isikman SO, Greenbaum A, Luo W, Coskun AF, Ozcan A PloS one 22984606 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/22984606
Lensfree microscopy on a cellphone. Tseng D, Mudanyali O, Oztoprak C, Isikman SO, Sencan I, Yaglidere O, Ozcan A Lab on a chip 20445943 Lab Chip 2010 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/20445943
Holographic pixel super-resolution in portable lensless on-chip microscopy using a fiber-optic array. Bishara W, Sikora U, Mudanyali O, Su TW, Yaglidere O, Luckhart S, Ozcan A Lab on a chip 21365087 Lab Chip 2011 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/21365087
Combined reflection and transmission microscope for telemedicine applications in field settings. Biener G, Greenbaum A, Isikman SO, Lee K, Tseng D, Ozcan A Lab on a chip 21709875 Lab Chip 2011 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/21709875
Lensfree fluorescent on-chip imaging of transgenic Caenorhabditis elegans over an ultra-wide field-of-view. Coskun AF, Sencan I, Su TW, Ozcan A PloS one 21253611 PLoS One 2011 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/21253611
Maskless imaging of dense samples using pixel super-resolution based multi-height lensfree on-chip microscopy. Greenbaum A, Ozcan A Optics express 22330550 Opt Express 2012 Jan 30 https://www.ncbi.nlm.nih.gov/pubmed/22330550
Toward giga-pixel nanoscopy on a chip: a computational wide-field look at the nano-scale without the use of lenses. McLeod E, Luo W, Mudanyali O, Greenbaum A, Ozcan A Lab on a chip 23592185 Lab Chip 2013 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/23592185
Quantification of plant chlorophyll content using Google Glass. Cortazar B, Koydemir HC, Tseng D, Feng S, Ozcan A Lab on a chip 25669673 Lab Chip 2015 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/25669673
Cellphone-based devices for bioanalytical sciences. Vashist SK, Mudanyali O, Schneider EM, Zengerle R, Ozcan A Analytical and bioanalytical chemistry 24287630 Anal Bioanal Chem 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24287630
Spectral demultiplexing in holographic and fluorescent on-chip microscopy. Sencan I, Coskun AF, Sikora U, Ozcan A Scientific reports 24441627 Sci Rep 2014 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/24441627
Albumin testing in urine using a smart-phone. Coskun AF, Nagi R, Sadeghi K, Phillips S, Ozcan A Lab on a chip 23995895 Lab Chip 2013 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/23995895
Giga-pixel fluorescent imaging over an ultra-large field-of-view using a flatbed scanner. Göröcs Z, Ling Y, Yu MD, Karahalios D, Mogharabi K, Lu K, Wei Q, Ozcan A Lab on a chip 24080766 Lab Chip 2013 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/24080766
On-chip biomedical imaging. Göröcs Z, Ozcan A IEEE reviews in biomedical engineering 23558399 IEEE Rev Biomed Eng 2013 https://www.ncbi.nlm.nih.gov/pubmed/23558399
Cellphone-based detection platform for rbST biomarker analysis in milk extracts using a microsphere fluorescence immunoassay. Ludwig SK, Zhu H, Phillips S, Shiledar A, Feng S, Tseng D, van Ginkel LA, Nielen MW, Ozcan A Analytical and bioanalytical chemistry 24972876 Anal Bioanal Chem 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/24972876
Optical detection and sizing of single nanoparticles using continuous wetting films. Hennequin Y, Allier CP, McLeod E, Mudanyali O, Migliozzi D, Ozcan A, Dinten JM ACS nano 23889001 ACS Nano 2013 Sep 24 https://www.ncbi.nlm.nih.gov/pubmed/23889001
Nanofabrication using near-field optical probes. McLeod E, Ozcan A Journal of laboratory automation 22713756 J Lab Autom 2012 Aug https://www.ncbi.nlm.nih.gov/pubmed/22713756
Detection of waterborne parasites using field-portable and cost-effective lensfree microscopy. Mudanyali O, Oztoprak C, Tseng D, Erlinger A, Ozcan A Lab on a chip 20694255 Lab Chip 2010 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/20694255
Lensless wide-field fluorescent imaging on a chip using compressive decoding of sparse objects. Coskun AF, Sencan I, Su TW, Ozcan A Optics express 20588904 Opt Express 2010 May 10 https://www.ncbi.nlm.nih.gov/pubmed/20588904
Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution. Bishara W, Su TW, Coskun AF, Ozcan A Optics express 20588977 Opt Express 2010 May 24 https://www.ncbi.nlm.nih.gov/pubmed/20588977
Lensfree holographic imaging of antibody microarrays for high-throughput detection of leukocyte numbers and function. Stybayeva G, Mudanyali O, Seo S, Silangcruz J, Macal M, Ramanculov E, Dandekar S, Erlinger A, Ozcan A, Revzin A Analytical chemistry 20359168 Anal Chem 2010 May 1 https://www.ncbi.nlm.nih.gov/pubmed/20359168
Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications. Mudanyali O, Tseng D, Oh C, Isikman SO, Sencan I, Bishara W, Oztoprak C, Seo S, Khademhosseini B, Ozcan A Lab on a chip 20401422 Lab Chip 2010 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/20401422
Optofluidic fluorescent imaging cytometry on a cell phone. Zhu H, Mavandadi S, Coskun AF, Yaglidere O, Ozcan A Analytical chemistry 21774454 Anal Chem 2011 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/21774454
Wide-field fluorescent microscopy on a cell-phone. Zhu H, Yaglidere O, Su TW, Tseng D, Ozcan A Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 22255900 Annu Int Conf IEEE Eng Med Biol Soc 2011 https://www.ncbi.nlm.nih.gov/pubmed/22255900
Field-portable reflection and transmission microscopy based on lensless holography. Lee M, Yaglidere O, Ozcan A Biomedical optics express 21991559 Biomed Opt Express 2011 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/21991559
Field-portable lensfree tomographic microscope. Isikman SO, Bishara W, Sikora U, Yaglidere O, Yeah J, Ozcan A Lab on a chip 21573311 Lab Chip 2011 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/21573311
On-chip differential interference contrast microscopy using lensless digital holography. Oh C, Isikman SO, Khademhosseinieh B, Ozcan A Optics express 20389485 Opt Express 2010 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/20389485
Lensfree On-Chip Microscopy and Tomography for Bio-Medical Applications. Isikman SO, Bishara W, Mudanyali O, Sencan I, Su TW, Tseng D, Yaglidere O, Sikora U, Ozcan A IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society 24478572 IEEE J Sel Top Quantum Electron 2011 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/24478572
Wide-field optical detection of nanoparticles using on-chip microscopy and self-assembled nanolenses. Mudanyali O, McLeod E, Luo W, Greenbaum A, Coskun AF, Hennequin Y, Allier CP, Ozcan A Nature photonics 24358054 Nat Photonics 2013 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/24358054
Holographic opto-fluidic microscopy. Bishara W, Zhu H, Ozcan A Optics express 21197025 Opt Express 2010 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/21197025
Lensfree on-chip holography facilitates novel microscopy applications. Ozcan A, Isikman S, Mudanyali O, Tseng D, Sencan I SPIE newsroom 21643449 SPIE Newsroom 2010 May 19 https://www.ncbi.nlm.nih.gov/pubmed/21643449
Optical imaging techniques for point-of-care diagnostics. Zhu H, Isikman SO, Mudanyali O, Greenbaum A, Ozcan A Lab on a chip 23044793 Lab Chip 2013 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/23044793
Lensfree optofluidic plasmonic sensor for real-time and label-free monitoring of molecular binding events over a wide field-of-view. Coskun AF, Cetin AE, Galarreta BC, Alvarez DA, Altug H, Ozcan A Scientific reports 25346102 Sci Rep 2014 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/25346102
Crowd-sourced BioGames: managing the big data problem for next-generation lab-on-a-chip platforms. Mavandadi S, Dimitrov S, Feng S, Yu F, Yu R, Sikora U, Ozcan A Lab on a chip 22918378 Lab Chip 2012 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/22918378
Optoelectronic tweezers integrated with lensfree holographic microscopy for wide-field interactive cell and particle manipulation on a chip. Huang KW, Su TW, Ozcan A, Chiou PY Lab on a chip 23661233 Lab Chip 2013 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/23661233
Nano-imaging enabled via self-assembly. McLeod E, Ozcan A Nano today 25506387 Nano Today 2014 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/25506387
Lensfree super-resolution holographic microscopy using wetting films on a chip. Mudanyali O, Bishara W, Ozcan A Optics express 21935102 Opt Express 2011 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/21935102
Lensless fluorescent microscopy on a chip. Coskun AF, Su TW, Sencan I, Ozcan A Journal of visualized experiments : JoVE 21876522 J Vis Exp 2011 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/21876522
Lensfree Fluorescent On-Chip Imaging using Compressive Sampling. Coskun AF, Su TW, Sencan I, Ozcan A Optics and photonics news 21546979 Opt Photonics News 2010 Dec 27 https://www.ncbi.nlm.nih.gov/pubmed/21546979
Lens-free optical tomographic microscope with a large imaging volume on a chip. Isikman SO, Bishara W, Mavandadi S, Yu FW, Feng S, Lau R, Ozcan A Proceedings of the National Academy of Sciences of the United States of America 21504943 Proc Natl Acad Sci U S A 2011 May 3 https://www.ncbi.nlm.nih.gov/pubmed/21504943
Biomedical imaging and sensing using flatbed scanners. Göröcs Z, Ozcan A Lab on a chip 24965011 Lab Chip 2014 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/24965011
Tunable vapor-condensed nanolenses. McLeod E, Nguyen C, Huang P, Luo W, Veli M, Ozcan A ACS nano 24979060 ACS Nano 2014 Jul 22 https://www.ncbi.nlm.nih.gov/pubmed/24979060
Immunochromatographic diagnostic test analysis using Google Glass. Feng S, Caire R, Cortazar B, Turan M, Wong A, Ozcan A ACS nano 24571349 ACS Nano 2014 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/24571349
Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools. Ozcan A Lab on a chip 24647550 Lab Chip 2014 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/24647550
Color and monochrome lensless on-chip imaging of Caenorhabditis elegans over a wide field-of-view. Isikman SO, Sencan I, Mudanyali O, Bishara W, Oztoprak C, Ozcan A Lab on a chip 20390127 Lab Chip 2010 May 7 https://www.ncbi.nlm.nih.gov/pubmed/20390127
Multi-angle lensless digital holography for depth resolved imaging on a chip. Su TW, Isikman SO, Bishara W, Tseng D, Erlinger A, Ozcan A Optics express 20588819 Opt Express 2010 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/20588819
Fluorescent imaging of single nanoparticles and viruses on a smart phone. Wei Q, Qi H, Luo W, Tseng D, Ki SJ, Wan Z, Göröcs Z, Bentolila LA, Wu TT, Sun R, Ozcan A ACS nano 24016065 ACS Nano 2013 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/24016065
BioGames: A Platform for Crowd-Sourced Biomedical Image Analysis and Telediagnosis. Mavandadi S, Feng S, Yu F, Dimitrov S, Yu R, Ozcan A Games for health journal 23724363 Games Health J 2012 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/23724363
Wide-field computational color imaging using pixel super-resolved on-chip microscopy. Greenbaum A, Feizi A, Akbari N, Ozcan A Optics express 23736466 Opt Express 2013 May 20 https://www.ncbi.nlm.nih.gov/pubmed/23736466
High-throughput lens-free blood analysis on a chip. Seo S, Isikman SO, Sencan I, Mudanyali O, Su TW, Bishara W, Erlinger A, Ozcan A Analytical chemistry 20450181 Anal Chem 2010 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/20450181
High-throughput screening of large volumes of whole blood using structured illumination and fluorescent on-chip imaging. Arpali SA, Arpali C, Coskun AF, Chiang HH, Ozcan A Lab on a chip 23047492 Lab Chip 2012 Dec 7 https://www.ncbi.nlm.nih.gov/pubmed/23047492
High-throughput lensfree 3D tracking of human sperms reveals rare statistics of helical trajectories. Su TW, Xue L, Ozcan A Proceedings of the National Academy of Sciences of the United States of America 22988076 Proc Natl Acad Sci U S A 2012 Oct 2 https://www.ncbi.nlm.nih.gov/pubmed/22988076
Partially coherent lensfree tomographic microscopy [Invited]. Isikman SO, Bishara W, Ozcan A Applied optics 22193016 Appl Opt 2011 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/22193016
Lensless fluorescent on-chip microscopy using a fiber-optic taper. Coskun AF, Sencan I, Su TW, Ozcan A Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 22255702 Annu Int Conf IEEE Eng Med Biol Soc 2011 https://www.ncbi.nlm.nih.gov/pubmed/22255702
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Directed growth of fibroblasts into three dimensional micropatterned geometries via self-assembling scaffolds. Jamal M, Bassik N, Cho JH, Randall CL, Gracias DH Biomaterials 20022106 Biomaterials 2010 Mar https://www.ncbi.nlm.nih.gov/pubmed/20022106
Stimuli-responsive theragrippers for chemomechanical controlled release. Malachowski K, Breger J, Kwag HR, Wang MO, Fisher JP, Selaru FM, Gracias DH Angewandte Chemie (International ed. in English) 24634136 Angew Chem Int Ed Engl 2014 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/24634136
Biopsy using a magnetic capsule endoscope carrying, releasing, and retrieving untethered microgrippers. Yim S, Gultepe E, Gracias DH, Sitti M IEEE transactions on bio-medical engineering 24108454 IEEE Trans Biomed Eng 2014 Feb https://www.ncbi.nlm.nih.gov/pubmed/24108454
Curving nanostructures using extrinsic stress. Cho JH, James T, Gracias DH Advanced materials (Deerfield Beach, Fla.) 20376856 Adv Mater 2010 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/20376856
Plastic deformation drives wrinkling, saddling, and wedging of annular bilayer nanostructures. Cho JH, Datta D, Park SY, Shenoy VB, Gracias DH Nano letters 21090597 Nano Lett 2010 Dec 8 https://www.ncbi.nlm.nih.gov/pubmed/21090597
Enabling cargo-carrying bacteria via surface attachment and triggered release. Fernandes R, Zuniga M, Sassine FR, Karakoy M, Gracias DH Small (Weinheim an der Bergstrasse, Germany) 21370460 Small 2011 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/21370460
Bio-origami hydrogel scaffolds composed of photocrosslinked PEG bilayers. Jamal M, Kadam SS, Xiao R, Jivan F, Onn TM, Fernandes R, Nguyen TD, Gracias DH Advanced healthcare materials 23386382 Adv Healthc Mater 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23386382
Self-folding single cell grippers. Malachowski K, Jamal M, Jin Q, Polat B, Morris CJ, Gracias DH Nano letters 24937214 Nano Lett 2014 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/24937214
Three-dimensional chemical patterns for cellular self-organization. Kalinin YV, Randhawa JS, Gracias DH Angewandte Chemie (International ed. in English) 21370335 Angew Chem Int Ed Engl 2011 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/21370335
Self-folding devices and materials for biomedical applications. Randall CL, Gultepe E, Gracias DH Trends in biotechnology 21764161 Trends Biotechnol 2012 Mar https://www.ncbi.nlm.nih.gov/pubmed/21764161
3D printed bionic ears. Mannoor MS, Jiang Z, James T, Kong YL, Malatesta KA, Soboyejo WO, Verma N, Gracias DH, McAlpine MC Nano letters 23635097 Nano Lett 2013 Jun 12 https://www.ncbi.nlm.nih.gov/pubmed/23635097
Three-dimensional fabrication at small size scales. Leong TG, Zarafshar AM, Gracias DH Small (Weinheim an der Bergstrasse, Germany) 20349446 Small 2010 Apr 9 https://www.ncbi.nlm.nih.gov/pubmed/20349446
Reversible actuation of microstructures by surface-chemical modification of thin-film bilayers. Randhawa JS, Keung MD, Tyagi P, Gracias DH Advanced materials (Deerfield Beach, Fla.) 20217729 Adv Mater 2010 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/20217729
Patternable nanowire sensors for electrochemical recording of dopamine. Tyagi P, Postetter D, Saragnese DL, Randall CL, Mirski MA, Gracias DH Analytical chemistry 19904993 Anal Chem 2009 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/19904993
Biopsy with thermally-responsive untethered microtools. Gultepe E, Randhawa JS, Kadam S, Yamanaka S, Selaru FM, Shin EJ, Kalloo AN, Gracias DH Advanced materials (Deerfield Beach, Fla.) 23047708 Adv Mater 2013 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/23047708
Silane surface modification for improved bioadhesion of esophageal stents. Karakoy M, Gultepe E, Pandey S, Khashab MA, Gracias DH Applied surface science 25663731 Appl Surf Sci 2014 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/25663731
Self-folding thermo-magnetically responsive soft microgrippers. Breger JC, Yoon C, Xiao R, Kwag HR, Wang MO, Fisher JP, Nguyen TD, Gracias DH ACS applied materials & interfaces 25594664 ACS Appl Mater Interfaces 2015 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/25594664
Microassembly based on hands free origami with bidirectional curvature. Bassik N, Stern GM, Gracias DH Applied physics letters 19787072 Appl Phys Lett 2009 Aug 31 https://www.ncbi.nlm.nih.gov/pubmed/19787072
Three dimensional nanofabrication using surface forces. Cho JH, Azam A, Gracias DH Langmuir : the ACS journal of surfaces and colloids 20507147 Langmuir 2010 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/20507147
Chemistry with spatial control using particles and streams(). Kalinin YV, Murali A, Gracias DH RSC advances 23145348 RSC Adv 2012 Oct 28 https://www.ncbi.nlm.nih.gov/pubmed/23145348
Hierarchical self-assembly of complex polyhedral microcontainers. Filipiak DJ, Azam A, Leong TG, Gracias DH Journal of micromechanics and microengineering : structures, devices, and systems 20161118 J Micromech Microeng 2009 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/20161118
Self-folding micropatterned polymeric containers. Azam A, Laflin KE, Jamal M, Fernandes R, Gracias DH Biomedical microdevices 20838901 Biomed Microdevices 2011 Feb https://www.ncbi.nlm.nih.gov/pubmed/20838901
Three-dimensional microwell arrays for cell culture. Randall CL, Kalinin YV, Jamal M, Manohar T, Gracias DH Lab on a chip 21063585 Lab Chip 2011 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/21063585
Self-assembly of lithographically patterned nanoparticles. Cho JH, Gracias DH Nano letters 19681638 Nano Lett 2009 Dec https://www.ncbi.nlm.nih.gov/pubmed/19681638
Voltage-gated ion transport through semiconducting conical nanopores formed by metal nanoparticle-assisted plasma etching. James T, Kalinin YV, Chan CC, Randhawa JS, Gaevski M, Gracias DH Nano letters 22725714 Nano Lett 2012 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/22725714
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, Apostolou E, Stadtfeld M, Li Y, Shioda T, Natesan S, Wagers AJ, Melnick A, Evans T, Hochedlinger K Nature biotechnology 20644536 Nat Biotechnol 2010 Aug https://www.ncbi.nlm.nih.gov/pubmed/20644536
Systemic signals regulate ageing and rejuvenation of blood stem cell niches. Mayack SR, Shadrach JL, Kim FS, Wagers AJ Nature 20110993 Nature 2010 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/20110993
Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT Cell 23663781 Cell 2013 May 9 https://www.ncbi.nlm.nih.gov/pubmed/23663781
In vivo gene editing in dystrophic mouse muscle and muscle stem cells. Tabebordbar M, Zhu K, Cheng JKW, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ Science (New York, N.Y.) 26721686 Science 2016 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/26721686
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Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states. El Ouaamari A, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qian WJ, Wagers AJ, Kulkarni RN Cell reports 23375376 Cell Rep 2013 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/23375376
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Rational design and synthesis of freestanding photoelectric nanodevices as highly efficient photocatalysts. Qu Y, Liao L, Cheng R, Wang Y, Lin YC, Huang Y, Duan X Nano letters 20373781 Nano Lett 2010 May 12 https://www.ncbi.nlm.nih.gov/pubmed/20373781
Top-gated graphene nanoribbon transistors with ultrathin high-k dielectrics. Liao L, Bai J, Cheng R, Lin YC, Jiang S, Huang Y, Duan X Nano letters 20380441 Nano Lett 2010 May 12 https://www.ncbi.nlm.nih.gov/pubmed/20380441
Highly spectral dependent enhancement of upconversion emission with sputtered gold island films. Zhang H, Xu D, Huang Y, Duan X Chemical communications (Cambridge, England) 21079884 Chem Commun (Camb) 2011 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/21079884
Porous silicon nanowires. Qu Y, Zhou H, Duan X Nanoscale 21869999 Nanoscale 2011 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/21869999
Plasmonic modulation of the upconversion fluorescence in NaYF4 :Yb/Tm hexaplate nanocrystals using gold nanoparticles or nanoshells. Zhang H, Li Y, Ivanov IA, Qu Y, Huang Y, Duan X Angewandte Chemie (International ed. in English) 20235253 Angew Chem Int Ed Engl 2010 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/20235253
Sub-100 nm channel length graphene transistors. Liao L, Bai J, Cheng R, Lin YC, Jiang S, Qu Y, Huang Y, Duan X Nano letters 20815334 Nano Lett 2010 Oct 13 https://www.ncbi.nlm.nih.gov/pubmed/20815334
pH-Operated mechanized porous silicon nanoparticles. Xue M, Zhong X, Shaposhnik Z, Qu Y, Tamanoi F, Duan X, Zink JI Journal of the American Chemical Society 21595466 J Am Chem Soc 2011 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/21595466
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High-performance top-gated graphene-nanoribbon transistors using zirconium oxide nanowires as high-dielectric-constant gate dielectrics. Liao L, Bai J, Lin YC, Qu Y, Huang Y, Duan X Advanced materials (Deerfield Beach, Fla.) 20526997 Adv Mater 2010 May 4 https://www.ncbi.nlm.nih.gov/pubmed/20526997
Nanoscale morphology, dimensional control, and electrical properties of oligoanilines. Wang Y, Tran HD, Liao L, Duan X, Kaner RB Journal of the American Chemical Society 20662516 J Am Chem Soc 2010 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/20662516
Unveiling the formation pathway of single crystalline porous silicon nanowires. Zhong X, Qu Y, Lin YC, Liao L, Duan X ACS applied materials & interfaces 21244020 ACS Appl Mater Interfaces 2011 Feb https://www.ncbi.nlm.nih.gov/pubmed/21244020
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Single-layer graphene on Al2O3/Si substrate: better contrast and higher performance of graphene transistors. Liao L, Bai J, Qu Y, Huang Y, Duan X Nanotechnology 19946170 Nanotechnology 2010 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/19946170
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Patient-to-patient variability in autologous pericardial matrix scaffolds for cardiac repair. Seif-Naraghi SB, Horn D, Schup-Magoffin PA, Madani MM, Christman KL Journal of cardiovascular translational research 21695575 J Cardiovasc Transl Res 2011 Oct https://www.ncbi.nlm.nih.gov/pubmed/21695575
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Award winner for outstanding research in the PhD category, 2014 Society for Biomaterials annual meeting and exposition, Denver, Colorado, April 16-19, 2014: Decellularized adipose matrix hydrogels stimulate in vivo neovascularization and adipose formation. Adam Young D, Bajaj V, Christman KL Journal of biomedical materials research. Part A 24510423 J Biomed Mater Res A 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24510423
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Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction. Rane AA, Chuang JS, Shah A, Hu DP, Dalton ND, Gu Y, Peterson KL, Omens JH, Christman KL PloS one 21731777 PLoS One 2011 https://www.ncbi.nlm.nih.gov/pubmed/21731777
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Antibacterial and cell-adhesive polypeptide and poly(ethylene glycol) hydrogel as a potential scaffold for wound healing. Song A, Rane AA, Christman KL Acta biomaterialia 22023748 Acta Biomater 2012 Jan https://www.ncbi.nlm.nih.gov/pubmed/22023748
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Catheter-deliverable hydrogel derived from decellularized ventricular extracellular matrix increases endogenous cardiomyocytes and preserves cardiac function post-myocardial infarction. Singelyn JM, Sundaramurthy P, Johnson TD, Schup-Magoffin PJ, Hu DP, Faulk DM, Wang J, Mayle KM, Bartels K, Salvatore M, Kinsey AM, Demaria AN, Dib N, Christman KL Journal of the American College of Cardiology 22340268 J Am Coll Cardiol 2012 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/22340268
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Microfluidic-SERS devices for one shot limit-of-detection. Kim D, Campos AR, Datt A, Gao Z, Rycenga M, Burrows ND, Greeneltch NG, Mirkin CA, Murphy CJ, Van Duyne RP, Haynes CL The Analyst 24756225 Analyst 2014 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/24756225
On-chip evaluation of shear stress effect on cytotoxicity of mesoporous silica nanoparticles. Kim D, Lin YS, Haynes CL Analytical chemistry 22032307 Anal Chem 2011 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/22032307
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Platelet Response to Allergens, CXCL10, and CXCL5 in the Context of Asthma. Gruba S, Wu X, Spanolios E, He J, Xiong-Hang K, Haynes CL ACS bio & med chem Au 36820311 ACS Bio Med Chem Au 2023 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/36820311
Bacterial capsular polysaccharide prevents the onset of asthma through T-cell activation. Johnson JL, Jones MB, Cobb BA Glycobiology 25347992 Glycobiology 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25347992
Infection, inflammation and host carbohydrates: a Glyco-Evasion Hypothesis. Kreisman LS, Cobb BA Glycobiology 22492234 Glycobiology 2012 Aug https://www.ncbi.nlm.nih.gov/pubmed/22492234
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Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells. Bloem K, García-Vallejo JJ, Vuist IM, Cobb BA, van Vliet SJ, van Kooyk Y Frontiers in immunology 23653626 Front Immunol 2013 https://www.ncbi.nlm.nih.gov/pubmed/23653626
Glycoantigens induce human peripheral Tr1 cell differentiation with gut-homing specialization. Kreisman LS, Cobb BA The Journal of biological chemistry 21228275 J Biol Chem 2011 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/21228275
Structural characterization and MHCII-dependent immunological properties of the zwitterionic O-chain antigen of Morganella morganii. Young NM, Kreisman LS, Stupak J, MacLean LL, Cobb BA, Richards JC Glycobiology 21321054 Glycobiology 2011 Oct https://www.ncbi.nlm.nih.gov/pubmed/21321054
Glycobiology of immune responses. Rabinovich GA, van Kooyk Y, Cobb BA Annals of the New York Academy of Sciences 22524422 Ann N Y Acad Sci 2012 Apr https://www.ncbi.nlm.nih.gov/pubmed/22524422
Neutrophils confer T cell resistance to myeloid-derived suppressor cell-mediated suppression to promote chronic inflammation. Ryan SO, Johnson JL, Cobb BA Journal of immunology (Baltimore, Md. : 1950) 23576679 J Immunol 2013 May 15 https://www.ncbi.nlm.nih.gov/pubmed/23576679
Mycobacterium tuberculosis synergizes with ATP to induce release of microvesicles and exosomes containing major histocompatibility complex class II molecules capable of antigen presentation. Ramachandra L, Qu Y, Wang Y, Lewis CJ, Cobb BA, Takatsu K, Boom WH, Dubyak GR, Harding CV Infection and immunity 20837713 Infect Immun 2010 Dec https://www.ncbi.nlm.nih.gov/pubmed/20837713
Myeloid glycosylation defects lead to a spontaneous common variable immunodeficiency-like condition with associated hemolytic anemia and antilymphocyte autoimmunity. Ryan SO, Abbott DW, Cobb BA Journal of immunology (Baltimore, Md. : 1950) 24795453 J Immunol 2014 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/24795453
Adaptive immune defects against glycoantigens in chronic granulomatous disease via dysregulated nitric oxide production. Lewis CJ, Cobb BA European journal of immunology 21630251 Eur J Immunol 2011 Sep https://www.ncbi.nlm.nih.gov/pubmed/21630251
Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness. Pathak A, Kumar S Integrative biology : quantitative biosciences from nano to macro 21210057 Integr Biol (Camb) 2011 Apr https://www.ncbi.nlm.nih.gov/pubmed/21210057
Biophysics and dynamics of natural and engineered stem cell microenvironments. Keung AJ, Healy KE, Kumar S, Schaffer DV Wiley interdisciplinary reviews. Systems biology and medicine 20836010 Wiley Interdiscip Rev Syst Biol Med 2010 Jan-Feb https://www.ncbi.nlm.nih.gov/pubmed/20836010
Cell-Matrix De-Adhesion Dynamics Reflect Contractile Mechanics. Sen S, Kumar S Cellular and molecular bioengineering 21297858 Cell Mol Bioeng 2009 Jun https://www.ncbi.nlm.nih.gov/pubmed/21297858
Combining mechanical and optical approaches to dissect cellular mechanobiology. Sen S, Kumar S Journal of biomechanics 19819457 J Biomech 2010 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/19819457
Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression. Lam WA, Cao L, Umesh V, Keung AJ, Sen S, Kumar S Molecular cancer 20144241 Mol Cancer 2010 Feb 10 https://www.ncbi.nlm.nih.gov/pubmed/20144241
Cell-matrix mechanobiology: applications to brain tumors and design of tissue engineering scaffolds. Kumar S Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 19964076 Annu Int Conf IEEE Eng Med Biol Soc 2009 https://www.ncbi.nlm.nih.gov/pubmed/19964076
The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Ulrich TA, de Juan Pardo EM, Kumar S Cancer research 19435897 Cancer Res 2009 May 15 https://www.ncbi.nlm.nih.gov/pubmed/19435897
A fluorescent peroxidase probe increases the sensitivity of commercial ELISAs by two orders of magnitude. Acharya AP, Nafisi PM, Gardner A, Mackay JL, Kundu K, Kumar S, Murthy N Chemical communications (Cambridge, England) 24071916 Chem Commun (Camb) 2013 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/24071916
Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform. Ananthanarayanan B, Kim Y, Kumar S Biomaterials 21820737 Biomaterials 2011 Nov https://www.ncbi.nlm.nih.gov/pubmed/21820737
Independent regulation of tumor cell migration by matrix stiffness and confinement. Pathak A, Kumar S Proceedings of the National Academy of Sciences of the United States of America 22689955 Proc Natl Acad Sci U S A 2012 Jun 26 https://www.ncbi.nlm.nih.gov/pubmed/22689955
Rho GTPases mediate the mechanosensitive lineage commitment of neural stem cells. Keung AJ, de Juan-Pardo EM, Schaffer DV, Kumar S Stem cells (Dayton, Ohio) 21956892 Stem Cells 2011 Nov https://www.ncbi.nlm.nih.gov/pubmed/21956892
From molecular signal activation to locomotion: an integrated, multiscale analysis of cell motility on defined matrices. Pathak A, Kumar S PloS one 21483802 PLoS One 2011 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/21483802
A composite hydrogel platform for the dissection of tumor cell migration at tissue interfaces. Rape AD, Kumar S Biomaterials 25047626 Biomaterials 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25047626
Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve. Gould RA, Yalcin HC, MacKay JL, Sauls K, Norris R, Kumar S, Butcher JT Current biology : CB 26725196 Curr Biol 2016 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/26725196
Vinculin tension distributions of individual stress fibers within cell-matrix adhesions. Chang CW, Kumar S Journal of cell science 23687380 J Cell Sci 2013 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/23687380
Microenvironmental stiffness enhances glioma cell proliferation by stimulating epidermal growth factor receptor signaling. Umesh V, Rape AD, Ulrich TA, Kumar S PloS one 25000176 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/25000176
Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells. Keung AJ, Asuri P, Kumar S, Schaffer DV Integrative biology : quantitative biosciences from nano to macro 22854634 Integr Biol (Camb) 2012 Sep https://www.ncbi.nlm.nih.gov/pubmed/22854634
Measuring the elastic properties of living cells with atomic force microscopy indentation. Mackay JL, Kumar S Methods in molecular biology (Clifton, N.J.) 23027009 Methods Mol Biol 2013 https://www.ncbi.nlm.nih.gov/pubmed/23027009
Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters. MacKay JL, Kumar S Integrative biology : quantitative biosciences from nano to macro 25044255 Integr Biol (Camb) 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25044255
Probing cellular mechanobiology in three-dimensional culture with collagen-agarose matrices. Ulrich TA, Jain A, Tanner K, MacKay JL, Kumar S Biomaterials 19926126 Biomaterials 2010 Mar https://www.ncbi.nlm.nih.gov/pubmed/19926126
Mechanics, malignancy, and metastasis: the force journey of a tumor cell. Kumar S, Weaver VM Cancer metastasis reviews 19153673 Cancer Metastasis Rev 2009 Jun https://www.ncbi.nlm.nih.gov/pubmed/19153673
Contributions of talin-1 to glioma cell-matrix tensional homeostasis. Sen S, Ng WP, Kumar S Journal of the Royal Society, Interface 22158841 J R Soc Interface 2012 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/22158841
Microtopographical assembly of cardiomyocytes. Patel AA, Desai TA, Kumar S Integrative biology : quantitative biosciences from nano to macro 21863181 Integr Biol (Camb) 2011 Oct https://www.ncbi.nlm.nih.gov/pubmed/21863181
Microscale mechanisms of agarose-induced disruption of collagen remodeling. Ulrich TA, Lee TG, Shon HK, Moon DW, Kumar S Biomaterials 21575987 Biomaterials 2011 Aug https://www.ncbi.nlm.nih.gov/pubmed/21575987
Dissecting regional variations in stress fiber mechanics in living cells with laser nanosurgery. Tanner K, Boudreau A, Bissell MJ, Kumar S Biophysical journal 21044574 Biophys J 2010 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/21044574
Pan-neuronal maturation but not neuronal subtype differentiation of adult neural stem cells is mechanosensitive. Keung AJ, Dong M, Schaffer DV, Kumar S Scientific reports 23660869 Sci Rep 2013 https://www.ncbi.nlm.nih.gov/pubmed/23660869
Differential Contributions of Nonmuscle Myosin II Isoforms and Functional Domains to Stress Fiber Mechanics. Chang CW, Kumar S Scientific reports 26336830 Sci Rep 2015 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/26336830
Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration. Pathak A, Kumar S Integrative biology : quantitative biosciences from nano to macro 23832051 Integr Biol (Camb) 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23832051
Contractility dominates adhesive ligand density in regulating cellular de-adhesion and retraction kinetics. Sen S, Ng WP, Kumar S Annals of biomedical engineering 21046466 Ann Biomed Eng 2011 Apr https://www.ncbi.nlm.nih.gov/pubmed/21046466
Three-dimensional patterning of multiple cell populations through orthogonal genetic control of cell motility. MacKay JL, Sood A, Kumar S Soft matter 24622945 Soft Matter 2014 Apr 14 https://www.ncbi.nlm.nih.gov/pubmed/24622945
A genetic strategy for the dynamic and graded control of cell mechanics, motility, and matrix remodeling. MacKay JL, Keung AJ, Kumar S Biophysical journal 22325265 Biophys J 2012 Feb 8 https://www.ncbi.nlm.nih.gov/pubmed/22325265
CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility. Kim Y, Kumar S Molecular cancer research : MCR 24962319 Mol Cancer Res 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/24962319
Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology. Sen S, Dong M, Kumar S PloS one 20037648 PLoS One 2009 Dec 23 https://www.ncbi.nlm.nih.gov/pubmed/20037648
Modulating malignant epithelial tumor cell adhesion, migration and mechanics with nanorod surfaces. Lee J, Chu BH, Sen S, Gupte A, Chancellor TJ, Chang CY, Ren F, Kumar S, Lele TP Biomedical microdevices 20830527 Biomed Microdevices 2011 Feb https://www.ncbi.nlm.nih.gov/pubmed/20830527
Presentation counts: microenvironmental regulation of stem cells by biophysical and material cues. Keung AJ, Kumar S, Schaffer DV Annual review of cell and developmental biology 20590452 Annu Rev Cell Dev Biol 2010 https://www.ncbi.nlm.nih.gov/pubmed/20590452
Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion. Wong SY, Ulrich TA, Deleyrolle LP, MacKay JL, Lin JM, Martuscello RT, Jundi MA, Reynolds BA, Kumar S Cancer research 25634210 Cancer Res 2015 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/25634210
Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival. Silva IA, Bai S, McLean K, Yang K, Griffith K, Thomas D, Ginestier C, Johnston C, Kueck A, Reynolds RK, Wicha MS, Buckanovich RJ Cancer research 21498635 Cancer Res 2011 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/21498635
EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH+ Ovarian Cancer Cells. Bai S, Ingram P, Chen YC, Deng N, Pearson A, Niknafs YS, O'Hayer P, Wang Y, Zhang ZY, Boscolo E, Bischoff J, Yoon E, Buckanovich RJ Cancer research 27803106 Cancer Res 2016 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/27803106
Ovarian cancer stem cell markers: prognostic and therapeutic implications. Burgos-Ojeda D, Rueda BR, Buckanovich RJ Cancer letters 22334034 Cancer Lett 2012 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/22334034
A novel model for evaluating therapies targeting human tumor vasculature and human cancer stem-like cells. Burgos-Ojeda D, McLean K, Bai S, Pulaski H, Gong Y, Silva I, Skorecki K, Tzukerman M, Buckanovich RJ Cancer research 23576551 Cancer Res 2013 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/23576551
Metformin targets ovarian cancer stem cells in vitro and in vivo. Shank JJ, Yang K, Ghannam J, Cabrera L, Johnston CJ, Reynolds RK, Buckanovich RJ Gynecologic oncology 22864111 Gynecol Oncol 2012 Nov https://www.ncbi.nlm.nih.gov/pubmed/22864111
F3-targeted cisplatin-hydrogel nanoparticles as an effective therapeutic that targets both murine and human ovarian tumor endothelial cells in vivo. Winer I, Wang S, Lee YE, Fan W, Gong Y, Burgos-Ojeda D, Spahlinger G, Kopelman R, Buckanovich RJ Cancer research 20959470 Cancer Res 2010 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/20959470
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K Cell stem cell 18371336 Cell Stem Cell 2007 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/18371336
Chromatin connections to pluripotency and cellular reprogramming. Orkin SH, Hochedlinger K Cell 21663790 Cell 2011 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/21663790
Modeling Rett syndrome with stem cells. Walsh RM, Hochedlinger K Cell 21074040 Cell 2010 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/21074040
The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. Sarkar A, Hochedlinger K Cell stem cell 23290134 Cell Stem Cell 2013 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/23290134
A reprogrammable mouse strain from gene-targeted embryonic stem cells. Stadtfeld M, Maherali N, Borkent M, Hochedlinger K Nature methods 20010832 Nat Methods 2010 Jan https://www.ncbi.nlm.nih.gov/pubmed/20010832
Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium. Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y Development (Cambridge, England) 23222438 Development 2013 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/23222438
Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice. Arnold K, Sarkar A, Yram MA, Polo JM, Bronson R, Sengupta S, Seandel M, Geijsen N, Hochedlinger K Cell stem cell 21982232 Cell Stem Cell 2011 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/21982232
Tgfbeta signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc. Maherali N, Hochedlinger K Current biology : CB 19765992 Curr Biol 2009 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/19765992
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, Natesan S, Kono T, Shioda T, Hochedlinger K Nature 20418860 Nature 2010 May 13 https://www.ncbi.nlm.nih.gov/pubmed/20418860
Induced pluripotent stem cells generated without viral integration. Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K Science (New York, N.Y.) 18818365 Science 2008 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/18818365
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Stadtfeld M, Maherali N, Breault DT, Hochedlinger K Cell stem cell 18371448 Cell Stem Cell 2008 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/18371448
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, Walsh RM, Khalil A, Rheinwald JG, Hochedlinger K Nature 19668190 Nature 2009 Aug 27 https://www.ncbi.nlm.nih.gov/pubmed/19668190
A high-efficiency system for the generation and study of human induced pluripotent stem cells. Maherali N, Ahfeldt T, Rigamonti A, Utikal J, Cowan C, Hochedlinger K Cell stem cell 18786420 Cell Stem Cell 2008 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/18786420
Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. Eminli S, Foudi A, Stadtfeld M, Maherali N, Ahfeldt T, Mostoslavsky G, Hock H, Hochedlinger K Nature genetics 19668214 Nat Genet 2009 Sep https://www.ncbi.nlm.nih.gov/pubmed/19668214
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β-Adrenergic Signaling Promotes Morphological Maturation of Astrocytes in Female Mice. Rosenberg MF, Godoy MI, Wade SD, Paredes MF, Zhang Y, Molofsky AV The Journal of neuroscience : the official journal of the Society for Neuroscience 37845031 J Neurosci 2023 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/37845031
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Interneuron Origins in the Embryonic Porcine Medial Ganglionic Eminence. Casalia ML, Li T, Ramsay H, Ross PJ, Paredes MF, Baraban SC The Journal of neuroscience : the official journal of the Society for Neuroscience 33637558 J Neurosci 2021 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/33637558
Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus. Sorrells SF, Paredes MF, Zhang Z, Kang G, Pastor-Alonso O, Biagiotti S, Page CE, Sandoval K, Knox A, Connolly A, Huang EJ, Garcia-Verdugo JM, Oldham MC, Yang Z, Alvarez-Buylla A The Journal of neuroscience : the official journal of the Society for Neuroscience 33762407 J Neurosci 2021 Mar 24 https://www.ncbi.nlm.nih.gov/pubmed/33762407
A CRISPR-engineered isogenic model of the 22q11.2 A-B syndromic deletion. Paranjape N, Lin YT, Flores-Ramirez Q, Sarin V, Johnson AB, Chu J, Paredes M, Wiita AP Scientific reports 37169815 Sci Rep 2023 May 11 https://www.ncbi.nlm.nih.gov/pubmed/37169815
Amplification of human interneuron progenitors promotes brain tumors and neurological defects. Eichmüller OL, Corsini NS, Vértesy Á, Morassut I, Scholl T, Gruber VE, Peer AM, Chu J, Novatchkova M, Hainfellner JA, Paredes MF, Feucht M, Knoblich JA Science (New York, N.Y.) 35084981 Science 2022 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/35084981
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Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy. Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V Neurology. Genetics 38586598 Neurol Genet 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38586598
The information bottleneck as a principle underlying multi-area cortical representations during decision-making. Kleinman M, Wang T, Xiao D, Feghhi E, Lee K, Carr N, Li Y, Hadidi N, Chandrasekaran C, Kao JC bioRxiv : the preprint server for biology 37502862 bioRxiv 2025 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/37502862
An artificial intelligence that increases simulated brain-computer interface performance. Olsen S, Zhang J, Liang KF, Lam M, Riaz U, Kao JC Journal of neural engineering 33978599 J Neural Eng 2021 May 13 https://www.ncbi.nlm.nih.gov/pubmed/33978599
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Non-invasive brain-machine interface control with artificial intelligence copilots. Lee JY, Lee S, Mishra A, Yan X, McMahan B, Gaisford B, Kobashigawa C, Qu M, Xie C, Kao JC bioRxiv : the preprint server for biology 39416032 bioRxiv 2024 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/39416032
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Combined GWAS and single cell transcriptomics uncover the underlying genes and cell types in disorders of gut-brain interaction. Majd A, Richter MN, Samuel RM, Cesiulis A, Ghazizadeh Z, Wang J, Fattahi F medRxiv : the preprint server for health sciences 37333423 medRxiv 2023 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/37333423
Stem Cell-Based Models for Studying the Effects of Cancer and Cancer Therapies on the Peripheral Nervous System. Richter MN, Fattahi F Advanced biology 35666079 Adv Biol (Weinh) 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35666079
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Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F Cell stem cell 33232663 Cell Stem Cell 2020 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/33232663
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A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality. Krishnan S, Dong C, Ratigan H, Morales-Rodriguez D, Cherian C, Sheffield M bioRxiv : the preprint server for biology 39651122 bioRxiv 2024 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/39651122
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A Hypothalamic Midbrain Pathway Essential for Driving Maternal Behaviors. Fang YY, Yamaguchi T, Song SC, Tritsch NX, Lin D Neuron 29621487 Neuron 2018 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/29621487
G protein-coupled receptors cooperate to silence dopamine neurons. Liu H, Tritsch NX The Journal of physiology 36214545 J Physiol 2022 Nov https://www.ncbi.nlm.nih.gov/pubmed/36214545
Silicon Nanowires for Intracellular Optical Interrogation with Subcellular Resolution. Rotenberg MY, Elbaz B, Nair V, Schaumann EN, Yamamoto N, Sarma N, Matino L, Santoro F, Tian B Nano letters 31904975 Nano Lett 2020 Feb 12 https://www.ncbi.nlm.nih.gov/pubmed/31904975
Inorganic semiconductor biointerfaces. Jiang Y, Tian B Nature reviews. Materials 31656635 Nat Rev Mater 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/31656635
Biomimetic Approaches Toward Smart Bio-hybrid Systems. Luo Z, Weiss DE, Liu Q, Tian B Nano research 30906509 Nano Res 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/30906509
Rational design of silicon structures for optically controlled multiscale biointerfaces. Jiang Y, Li X, Liu B, Yi J, Fang Y, Shi F, Gao X, Sudzilovsky E, Parameswaran R, Koehler K, Nair V, Yue J, Guo K, Fang Y, Tsai HM, Freyermuth G, Wong RCS, Kao CM, Chen CT, Nicholls AW, Wu X, Shepherd GMG, Tian B Nature biomedical engineering 30906646 Nat Biomed Eng 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/30906646
Alloy-assisted deposition of three-dimensional arrays of atomic gold catalyst for crystal growth studies. Fang Y, Jiang Y, Cherukara MJ, Shi F, Koehler K, Freyermuth G, Isheim D, Narayanan B, Nicholls AW, Seidman DN, Sankaranarayanan SKRS, Tian B Nature communications 29222439 Nat Commun 2017 Dec 8 https://www.ncbi.nlm.nih.gov/pubmed/29222439
Nongenetic Optical Methods for Measuring and Modulating Neuronal Response. Zimmerman JF, Tian B ACS nano 29727159 ACS Nano 2018 May 22 https://www.ncbi.nlm.nih.gov/pubmed/29727159
Learning from Solar Energy Conversion: Biointerfaces for Artificial Photosynthesis and Biological Modulation. Lee YV, Tian B Nano letters 30888185 Nano Lett 2019 Mar 21 https://www.ncbi.nlm.nih.gov/pubmed/30888185
Talking to cells: semiconductor nanomaterials at the cellular interface. Rotenberg MY, Tian B Advanced biosystems 30906852 Adv Biosyst 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/30906852
Dissecting Biological and Synthetic Soft-Hard Interfaces for Tissue-Like Systems. Fang Y, Yang X, Lin Y, Shi J, Prominski A, Clayton C, Ostroff E, Tian B Chemical reviews 34677943 Chem Rev 2022 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/34677943
Soft-Hard Composites for Bioelectric Interfaces. Lin Y, Fang Y, Yue J, Tian B Trends in chemistry 34296076 Trends Chem 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/34296076
Laser writing of nitrogen-doped silicon carbide for biological modulation. Nair V, Yi J, Isheim D, Rotenberg M, Meng L, Shi F, Chen X, Gao X, Prominski A, Jiang Y, Yue J, Gallagher CT, Seidman DN, Tian B Science advances 32937377 Sci Adv 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32937377
Recent advances in bioelectronics chemistry. Fang Y , Meng L , Prominski A , Schaumann EN , Seebald M , Tian B Chemical Society reviews 32672777 Chem Soc Rev 2020 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/32672777
Photoelectrochemical modulation of neuronal activity with free-standing coaxial silicon nanowires. Parameswaran R, Carvalho-de-Souza JL, Jiang Y, Burke MJ, Zimmerman JF, Koehler K, Phillips AW, Yi J, Adams EJ, Bezanilla F, Tian B Nature nanotechnology 29459654 Nat Nanotechnol 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29459654
Nano-enabled cellular engineering for bioelectric studies. Shi J, Clayton C, Tian B Nano research 34295455 Nano Res 2020 May https://www.ncbi.nlm.nih.gov/pubmed/34295455
Nongenetic optical neuromodulation with silicon-based materials. Jiang Y, Parameswaran R, Li X, Carvalho-de-Souza JL, Gao X, Meng L, Bezanilla F, Shepherd GMG, Tian B Nature protocols 30980031 Nat Protoc 2019 May https://www.ncbi.nlm.nih.gov/pubmed/30980031
Nanowired Bioelectric Interfaces. Tian B, Lieber CM Chemical reviews 30995019 Chem Rev 2019 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/30995019
Optical stimulation of cardiac cells with a polymer-supported silicon nanowire matrix. Parameswaran R, Koehler K, Rotenberg MY, Burke MJ, Kim J, Jeong KY, Hissa B, Paul MD, Moreno K, Sarma N, Hayes T, Sudzilovsky E, Park HG, Tian B Proceedings of the National Academy of Sciences of the United States of America 30538202 Proc Natl Acad Sci U S A 2019 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/30538202
Living myofibroblast-silicon composites for probing electrical coupling in cardiac systems. Rotenberg MY, Yamamoto N, Schaumann EN, Matino L, Santoro F, Tian B Proceedings of the National Academy of Sciences of the United States of America 31624124 Proc Natl Acad Sci U S A 2019 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/31624124
An atlas of nano-enabled neural interfaces. Acarón Ledesma H, Li X, Carvalho-de-Souza JL, Wei W, Bezanilla F, Tian B Nature nanotechnology 31270446 Nat Nanotechnol 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31270446
Texturing Silicon Nanowires for Highly Localized Optical Modulation of Cellular Dynamics. Fang Y, Jiang Y, Acaron Ledesma H, Yi J, Gao X, Weiss DE, Shi F, Tian B Nano letters 29894630 Nano Lett 2018 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/29894630
Micelle-enabled self-assembly of porous and monolithic carbon membranes for bioelectronic interfaces. Fang Y, Prominski A, Rotenberg MY, Meng L, Acarón Ledesma H, Lv Y, Yue J, Schaumann E, Jeong J, Yamamoto N, Jiang Y, Elbaz B, Wei W, Tian B Nature nanotechnology 33288948 Nat Nanotechnol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33288948
Tracking Longitudinal Rotation of Silicon Nanowires for Biointerfaces. Lee YV, Wu D, Fang Y, Peng Y, Tian B Nano letters 32208712 Nano Lett 2020 May 13 https://www.ncbi.nlm.nih.gov/pubmed/32208712
Biological Interfaces, Modulation, and Sensing with Inorganic Nano-Bioelectronic Materials. Schaumann EN, Tian B Small methods 34295965 Small Methods 2020 May 11 https://www.ncbi.nlm.nih.gov/pubmed/34295965
Electrical signals in the ER are cell type and stimulus specific with extreme spatial compartmentalization in neurons. Campbell EP, Abushawish AA, Valdez LA, Bell MK, Haryono M, Rangamani P, Bloodgood BL Cell reports 36640310 Cell Rep 2023 Jan 31 https://www.ncbi.nlm.nih.gov/pubmed/36640310
Experimental and statistical reevaluation provides no evidence for Drosophila courtship song rhythms. Stern DL, Clemens J, Coen P, Calhoun AJ, Hogenesch JB, Arthur BJ, Murthy M Proceedings of the National Academy of Sciences of the United States of America 28851830 Proc Natl Acad Sci U S A 2017 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/28851830
Singing on the fly: sensorimotor integration and acoustic communication in Drosophila. Coen P, Murthy M Current opinion in neurobiology 26874218 Curr Opin Neurobiol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/26874218
Discovery of a New Song Mode in Drosophila Reveals Hidden Structure in the Sensory and Neural Drivers of Behavior. Clemens J, Coen P, Roemschied FA, Pereira TD, Mazumder D, Aldarondo DE, Pacheco DA, Murthy M Current biology : CB 30057309 Curr Biol 2018 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/30057309
Cell-Type-Specific Transcriptome Analysis in the Drosophila Mushroom Body Reveals Memory-Related Changes in Gene Expression. Crocker A, Guan XJ, Murphy CT, Murthy M Cell reports 27160913 Cell Rep 2016 May 17 https://www.ncbi.nlm.nih.gov/pubmed/27160913
Auditory activity is diverse and widespread throughout the central brain of Drosophila. Pacheco DA, Thiberge SY, Pnevmatikakis E, Murthy M Nature neuroscience 33230320 Nat Neurosci 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33230320
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Shared Song Detector Neurons in Drosophila Male and Female Brains Drive Sex-Specific Behaviors. Deutsch D, Clemens J, Thiberge SY, Guan G, Murthy M Current biology : CB 31564492 Curr Biol 2019 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/31564492
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Extracting structural and functional features of widely distributed biological circuits with single cell resolution via tissue clearing and delivery vectors. Treweek JB, Gradinaru V Current opinion in biotechnology 27393829 Curr Opin Biotechnol 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27393829
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Light-guided sectioning for precise in situ localization and tissue interface analysis for brain-implanted optical fibers and GRIN lenses. Kahan A, Greenbaum A, Jang MJ, Robinson JE, Cho JR, Chen X, Kassraian P, Wagenaar DA, Gradinaru V Cell reports 34592157 Cell Rep 2021 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/34592157
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Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics. Bedbrook CN, Yang KK, Robinson JE, Mackey ED, Gradinaru V, Arnold FH Nature methods 31611694 Nat Methods 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31611694
Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo. Bedbrook CN, Kato M, Ravindra Kumar S, Lakshmanan A, Nath RD, Sun F, Sternberg PW, Arnold FH, Gradinaru V Chemistry & biology 26211362 Chem Biol 2015 Aug 20 https://www.ncbi.nlm.nih.gov/pubmed/26211362
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Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways. Xiao C, Cho JR, Zhou C, Treweek JB, Chan K, McKinney SL, Yang B, Gradinaru V Neuron 27100197 Neuron 2016 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/27100197
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Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies. Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, Shivkumar K Nature communications 31028266 Nat Commun 2019 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/31028266
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Plasmodium falciparum infection in humans and mosquitoes influence natural Anopheline biting behavior and transmission. Markwalter CF, Lapp Z, Abel L, Kimachas E, Omollo E, Freedman E, Chepkwony T, Amunga M, McCormick T, Bérubé S, Mangeni JN, Wesolowski A, Obala AA, Taylor SM, Prudhomme O'Meara W Nature communications 38816383 Nat Commun 2024 May 30 https://www.ncbi.nlm.nih.gov/pubmed/38816383
Consistently estimating network statistics using aggregated relational data. Breza E, Chandrasekhar AG, Lubold S, McCormick TH, Pan M Proceedings of the National Academy of Sciences of the United States of America 37192169 Proc Natl Acad Sci U S A 2023 May 23 https://www.ncbi.nlm.nih.gov/pubmed/37192169
Using Aggregated Relational Data to Feasibly Identify Network Structure without Network Data. Breza E, Chandrasekhar AG, McCormick TH, Pan M The American economic review 34526729 Am Econ Rev 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/34526729
Using Bayesian Latent Gaussian Graphical Models to Infer Symptom Associations in Verbal Autopsies. Li ZR, McComick TH, Clark SJ Bayesian analysis 33273996 Bayesian Anal 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/33273996
Comparing the Robustness of Simple Network Scale-Up Method Estimators. Kunke JP, Laga I, Niu X, McCormick TH Sociological methodology 39391075 Sociol Methodol 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/39391075
Quantifying heterogeneity in SARS-CoV-2 transmission during the lockdown in India. Arinaminpathy N, Das J, McCormick TH, Mukhopadhyay P, Sircar N Epidemics 34171509 Epidemics 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34171509
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A FLEXIBLE BAYESIAN FRAMEWORK TO ESTIMATE AGE- AND CAUSE-SPECIFIC CHILD MORTALITY OVER TIME FROM SAMPLE REGISTRATION DATA. Schumacher AE, McCormick TH, Wakefield J, Chu Y, Perin J, Villavicencio F, Simon N, Liu L The annals of applied statistics 37621750 Ann Appl Stat 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/37621750
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Arousal and Locomotion Differently Modulate Activity of Somatostatin Neurons across Cortex. Khoury CF, Fala NG, Runyan CA eNeuro 37169583 eNeuro 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37169583
Simultaneous interneuron labeling reveals cell type-specific, population-level interactions in cortex. Potter CT, Bassi CD, Runyan CA iScience 39280622 iScience 2024 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/39280622
Different state-dependence of population codes across cortex. Bandi AC, Runyan CA bioRxiv : the preprint server for biology 38826351 bioRxiv 2024 May 26 https://www.ncbi.nlm.nih.gov/pubmed/38826351
Local Differences in Network Organization in the Auditory and Parietal Cortex, Revealed with Single Neuron Activation. Khoury CF, Ferrone M, Runyan CA The Journal of neuroscience : the official journal of the Society for Neuroscience 39890466 J Neurosci 2025 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/39890466
The spatial scale of somatostatin subnetworks increases from sensory to association cortex. Khoury CF, Fala NG, Runyan CA Cell reports 36070697 Cell Rep 2022 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/36070697
Simultaneous interneuron labeling reveals population-level interactions among parvalbumin, somatostatin, and pyramidal neurons in cortex. Potter C, Bassi C, Runyan CA bioRxiv : the preprint server for biology 36711788 bioRxiv 2024 Feb 2 https://www.ncbi.nlm.nih.gov/pubmed/36711788
Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants. McAfee JC, Lee S, Lee J, Bell JL, Krupa O, Davis J, Insigne K, Bond ML, Zhao N, Boyle AP, Phanstiel DH, Love MI, Stein JL, Ruzicka WB, Davila-Velderrain J, Kosuri S, Won H Cell genomics 37868037 Cell Genom 2023 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/37868037
A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles. Sey NYA, Hu B, Mah W, Fauni H, McAfee JC, Rajarajan P, Brennand KJ, Akbarian S, Won H Nature neuroscience 32152537 Nat Neurosci 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32152537
Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism. Matoba N, Liang D, Sun H, Aygün N, McAfee JC, Davis JE, Raffield LM, Qian H, Piven J, Li Y, Kosuri S, Won H, Stein JL Translational psychiatry 32747698 Transl Psychiatry 2020 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/32747698
Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders. Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S, PsychENCODE Consortium, Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH Nature communications 34172755 Nat Commun 2021 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/34172755
Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia. Wen J, Trost B, Engchuan W, Halvorsen M, Pallotto LM, Mitina A, Ancalade N, Farrell M, Backstrom I, Guo K, Pellecchia G, Thiruvahindrapuram B, Giusti-Rodriguez P, Rosen JD, Li Y, Won H, Magnusson PKE, Gyllensten U, Bassett AS, Hultman CM, Sullivan PF, Yuen RKC, Szatkiewicz JP Molecular psychiatry 36380236 Mol Psychiatry 2023 Jan https://www.ncbi.nlm.nih.gov/pubmed/36380236
Annotating genetic variants to target genes using H-MAGMA. Sey NYA, Pratt BM, Won H Nature protocols 36289406 Nat Protoc 2023 Jan https://www.ncbi.nlm.nih.gov/pubmed/36289406
Chromatin loop dynamics during cellular differentiation are associated with changes to both anchor and internal regulatory features. Bond ML, Davis ES, Quiroga IY, Dey A, Kiran M, Love MI, Won H, Phanstiel DH Genome research 37699658 Genome Res 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37699658
Regulatory landscape in brain development and disease. Spiess K, Won H Current opinion in genetics & development 32563855 Curr Opin Genet Dev 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32563855
Focus on your locus with a massively parallel reporter assay. McAfee JC, Bell JL, Krupa O, Matoba N, Stein JL, Won H Journal of neurodevelopmental disorders 36085003 J Neurodev Disord 2022 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/36085003
Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex. Liu S, Won H, Clarke D, Matoba N, Khullar S, Mu Y, Wang D, Gerstein M Genome medicine 36424644 Genome Med 2022 Nov 24 https://www.ncbi.nlm.nih.gov/pubmed/36424644
Advances in profiling chromatin architecture shed light on the regulatory dynamics underlying brain disorders. Pratt BM, Won H Seminars in cell & developmental biology 34483043 Semin Cell Dev Biol 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34483043
Schizophrenia-Linked Protein tSNARE1 Regulates Endosomal Trafficking in Cortical Neurons. Plooster M, Rossi G, Farrell MS, McAfee JC, Bell JL, Ye M, Diering GH, Won H, Gupton SL, Brennwald P The Journal of neuroscience : the official journal of the Society for Neuroscience 34642214 J Neurosci 2021 Nov 10 https://www.ncbi.nlm.nih.gov/pubmed/34642214
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. Quach BC, Bray MJ, Gaddis NC, Liu M, Palviainen T, Minica CC, Zellers S, Sherva R, Aliev F, Nothnagel M, Young KA, Marks JA, Young H, Carnes MU, Guo Y, Waldrop A, Sey NYA, Landi MT, McNeil DW, Drichel D, Farrer LA, Markunas CA, Vink JM, Hottenga JJ, Iacono WG, Kranzler HR, Saccone NL, Neale MC, Madden P, Rietschel M, Marazita ML, McGue M, Won H, Winterer G, Grucza R, Dick DM, Gelernter J, Caporaso NE, Baker TB, Boomsma DI, Kaprio J, Hokanson JE, Vrieze S, Bierut LJ, Johnson EO, Hancock DB Nature communications 33144568 Nat Commun 2020 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/33144568
Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism. Ramaswami G, Won H, Gandal MJ, Haney J, Wang JC, Wong CCY, Sun W, Prabhakar S, Mill J, Geschwind DH Nature communications 32978376 Nat Commun 2020 Sep 25 https://www.ncbi.nlm.nih.gov/pubmed/32978376
Chromatin architecture provides a roadmap to improve our understanding of psychiatric disorders. Hu B, Won H Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 32859998 Neuropsychopharmacology 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/32859998
Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits. Sey NYA, Hu B, Iskhakova M, Lee S, Sun H, Shokrian N, Ben Hutta G, Marks JA, Quach BC, Johnson EO, Hancock DB, Akbarian S, Won H Molecular psychiatry 35422469 Mol Psychiatry 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35422469
Limited Association between Schizophrenia Genetic Risk Factors and Transcriptomic Features. Yu AW, Peery JD, Won H Genes 34356078 Genes (Basel) 2021 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/34356078
HIV integration in the human brain is linked to microglial activation and 3D genome remodeling. Plaza-Jennings AL, Valada A, O'Shea C, Iskhakova M, Hu B, Javidfar B, Ben Hutta G, Lambert TY, Murray J, Kassim B, Chandrasekaran S, Chen BK, Morgello S, Won H, Akbarian S Molecular cell 36525955 Mol Cell 2022 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/36525955
Convergence and Divergence of Rare Genetic Disorders on Brain Phenotypes: A Review. Raznahan A, Won H, Glahn DC, Jacquemont S JAMA psychiatry 35767289 JAMA Psychiatry 2022 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/35767289
Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders. Lee S, McAfee JC, Lee J, Gomez A, Ledford AT, Clarke D, Min H, Gerstein MB, Boyle AP, Sullivan PF, Beltran AS, Won H Cell 39848247 Cell 2025 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/39848247
Viscera affectum anno: the gut beyond eating behaviours. Bohórquez DV Nature reviews. Gastroenterology & hepatology 33262502 Nat Rev Gastroenterol Hepatol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33262502
Deciphering visceral instincts: a scientific quest to unravel food choices from molecules to mind. Alway E, Reicher N, Bohórquez DV Genes & development 39362782 Genes Dev 2024 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/39362782
The preference for sugar over sweetener depends on a gut sensor cell. Buchanan KL, Rupprecht LE, Kaelberer MM, Sahasrabudhe A, Klein ME, Villalobos JA, Liu WW, Yang A, Gelman J, Park S, Anikeeva P, Bohórquez DV Nature neuroscience 35027761 Nat Neurosci 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/35027761
The nerve not taken. Rupprecht LE, Bohórquez DV Cell metabolism 33657390 Cell Metab 2021 Mar 2 https://www.ncbi.nlm.nih.gov/pubmed/33657390
Neuropod Cells: The Emerging Biology of Gut-Brain Sensory Transduction. Kaelberer MM, Rupprecht LE, Liu WW, Weng P, Bohórquez DV Annual review of neuroscience 32101483 Annu Rev Neurosci 2020 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/32101483
Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits. Sahasrabudhe A, Rupprecht LE, Orguc S, Khudiyev T, Tanaka T, Sands J, Zhu W, Tabet A, Manthey M, Allen H, Loke G, Antonini MJ, Rosenfeld D, Park J, Garwood IC, Yan W, Niroui F, Fink Y, Chandrakasan A, Bohórquez DV, Anikeeva P Nature biotechnology 37349522 Nat Biotechnol 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/37349522
The neural basis of sugar preference. Liu WW, Bohórquez DV Nature reviews. Neuroscience 35879409 Nat Rev Neurosci 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/35879409
Dopamine, Updated: Reward Prediction Error and Beyond. Lerner TN, Holloway AL, Seiler JL Current opinion in neurobiology 33197709 Curr Opin Neurobiol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33197709
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Dopamine signaling in the dorsomedial striatum promotes compulsive behavior. Seiler JL, Cosme CV, Sherathiya VN, Schaid MD, Bianco JM, Bridgemohan AS, Lerner TN Current biology : CB 35134327 Curr Biol 2022 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/35134327
Interfacing behavioral and neural circuit models for habit formation. Lerner TN Journal of neuroscience research 31916623 J Neurosci Res 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/31916623
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Hidden variables in stress neurobiology research. Holloway AL, Lerner TN Trends in neurosciences 37985263 Trends Neurosci 2024 Jan https://www.ncbi.nlm.nih.gov/pubmed/37985263
Chronically dysregulated corticosterone impairs dopaminergic transmission in the dorsomedial striatum by sex-divergent mechanisms. Holloway AL, Schaid MD, Lerner TN Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 36810463 Neuropsychopharmacology 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/36810463
How Dopamine Enables Learning from Aversion. Lopez GC, Lerner TN Current opinion in behavioral sciences 39719969 Curr Opin Behav Sci 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39719969
Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution. Pollen AA, Kilik U, Lowe CB, Camp JG Nature reviews. Genetics 36737647 Nat Rev Genet 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/36737647
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Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex. Deng C, Whalen S, Steyert M, Ziffra R, Przytycki PF, Inoue F, Pereira DA, Capauto D, Norton S, Vaccarino FM, Pollen A, Nowakowski TJ, Ahituv N, Pollard KS bioRxiv : the preprint server for biology 36824845 bioRxiv 2023 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/36824845
Three-dimensional genome rewiring in loci with human accelerated regions. Keough KC, Whalen S, Inoue F, Przytycki PF, Fair T, Deng C, Steyert M, Ryu H, Lindblad-Toh K, Karlsson E, Zoonomia Consortium§, Nowakowski T, Ahituv N, Pollen A, Pollard KS Science (New York, N.Y.) 37104607 Science 2023 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/37104607
Mapping cis- and trans-regulatory target genes of human-specific deletions. Fair T, Pavlovic BJ, Swope D, Castillo OE, Schaefer NK, Pollen AA bioRxiv : the preprint server for biology 38234800 bioRxiv 2024 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/38234800
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Comparative landscape of genetic dependencies in human and chimpanzee stem cells. She R, Fair T, Schaefer NK, Saunders RA, Pavlovic BJ, Weissman JS, Pollen AA bioRxiv : the preprint server for biology 36993685 bioRxiv 2023 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/36993685
Genetic architecture of human brain evolution. Fair T, Pollen AA Current opinion in neurobiology 37003107 Curr Opin Neurobiol 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/37003107
Machine learning dissection of human accelerated regions in primate neurodevelopment. Whalen S, Inoue F, Ryu H, Fair T, Markenscoff-Papadimitriou E, Keough K, Kircher M, Martin B, Alvarado B, Elor O, Laboy Cintron D, Williams A, Hassan Samee MA, Thomas S, Krencik R, Ullian EM, Kriegstein A, Rubenstein JL, Shendure J, Pollen AA, Ahituv N, Pollard KS Neuron 36640767 Neuron 2023 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/36640767
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Reverse engineering human brain evolution using organoid models. Mostajo-Radji MA, Schmitz MT, Montoya ST, Pollen AA Brain research 31809699 Brain Res 2020 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/31809699
Conservation, alteration, and redistribution of mammalian striatal interneurons. Corrigan EK, DeBerardine M, Poddar A, Turrero García M, Schmitz MT, Harwell CC, Paredes MF, Krienen FM, Pollen AA bioRxiv : the preprint server for biology 39131311 bioRxiv 2024 Jul 29 https://www.ncbi.nlm.nih.gov/pubmed/39131311
The lab on lockdown: thinking back and looking ahead. Poe GR, Cai DJ Nature reviews. Neuroscience 32699293 Nat Rev Neurosci 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32699293
Chronotate: An open-source tool for manual timestamping and quantification of animal behavior. Philipsberg PA, Christenson Wick Z, Diego KS, Vaughan N, Galas A, Jurkowski A, Feng Y, Vetere LM, Chen L, Soler I, Cai DJ, Shuman T Neuroscience letters 37619698 Neurosci Lett 2023 Sep 25 https://www.ncbi.nlm.nih.gov/pubmed/37619698
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior. Blaze J, Navickas A, Phillips HL, Heissel S, Plaza-Jennings A, Miglani S, Asgharian H, Foo M, Katanski CD, Watkins CP, Pennington ZT, Javidfar B, Espeso-Gil S, Rostandy B, Alwaseem H, Hahn CG, Molina H, Cai DJ, Pan T, Yao WD, Goodarzi H, Haghighi F, Akbarian S Nature communications 34389722 Nat Commun 2021 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/34389722
Aversive experience drives offline ensemble reactivation to link memories across days. Zaki Y, Pennington ZT, Morales-Rodriguez D, Francisco TR, LaBanca AR, Dong Z, Lamsifer S, Segura SC, Chen HT, Wick ZC, Silva AJ, van der Meer M, Shuman T, Fenton A, Rajan K, Cai DJ bioRxiv : the preprint server for biology 36993254 bioRxiv 2023 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/36993254
ezTrack-A Step-by-Step Guide to Behavior Tracking. Pennington ZT, Diego KS, Francisco TR, LaBanca AR, Lamsifer SI, Liobimova O, Shuman T, Cai DJ Current protocols 34610215 Curr Protoc 2021 Oct https://www.ncbi.nlm.nih.gov/pubmed/34610215
The brain in motion: How ensemble fluidity drives memory-updating and flexibility. Mau W, Hasselmo ME, Cai DJ eLife 33372892 Elife 2020 Dec 29 https://www.ncbi.nlm.nih.gov/pubmed/33372892
A Double Hit of Social and Economic Stress in Mice Precipitates Changes in Decision-Making Strategies. Durand-de Cuttoli R, Martínez-Rivera FJ, Li L, Minier-Toribio A, Dong Z, Cai DJ, Russo SJ, Nestler EJ, Sweis BM Biological psychiatry 38141911 Biol Psychiatry 2024 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/38141911
Simultaneous dual-color calcium imaging in freely-behaving mice. Dong Z, Feng Y, Diego K, Baggetta AM, Sweis BM, Pennington ZT, Lamsifer SI, Zaki Y, Sangiuliano F, Philipsberg PA, Morales-Rodriguez D, Kircher D, Slesinger P, Shuman T, Aharoni D, Cai DJ bioRxiv : the preprint server for biology 39005306 bioRxiv 2024 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/39005306
Memory engram stability and flexibility. Zaki Y, Cai DJ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 39300271 Neuropsychopharmacology 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/39300271
Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer's disease pathology. Vetere LM, Galas AM, Vaughan N, Feng Y, Wick ZC, Philipsberg PA, Liobimova O, Fernandez-Ruiz A, Cai DJ, Shuman T bioRxiv : the preprint server for biology 39868201 bioRxiv 2025 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/39868201
Creating Space for Synaptic Formation-A New Role for Microglia in Synaptic Plasticity. Zaki Y, Cai DJ Cell 32707091 Cell 2020 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/32707091
The role of intrinsic excitability in the evolution of memory: Significance in memory allocation, consolidation, and updating. Chen L, Cummings KA, Mau W, Zaki Y, Dong Z, Rabinowitz S, Clem RL, Shuman T, Cai DJ Neurobiology of learning and memory 32512183 Neurobiol Learn Mem 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32512183
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Dynamic and heterogeneous neural ensembles contribute to a memory engram. Sweis BM, Mau W, Rabinowitz S, Cai DJ Current opinion in neurobiology 33388602 Curr Opin Neurobiol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33388602
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Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior. Pennington ZT, LaBanca AR, Sompolpong P, Abdel-Raheim SD, Ko B, Christenson Wick Z, Feng Y, Dong Z, Francisco TR, Bacon ME, Chen L, Fulton SL, Maze I, Shuman T, Cai DJ bioRxiv : the preprint server for biology 36945605 bioRxiv 2024 May 8 https://www.ncbi.nlm.nih.gov/pubmed/36945605
Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy. Feng Y, Diego KS, Dong Z, Wick ZC, Page-Harley L, Page-Harley V, Schnipper J, Lamsifer SI, Pennington ZT, Vetere LM, Philipsberg PA, Soler I, Jurkowski A, Rosado CJ, Khan NN, Cai DJ, Shuman T bioRxiv : the preprint server for biology 38559224 bioRxiv 2024 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/38559224
Progressive Excitability Changes in the Medial Entorhinal Cortex in the 3xTg Mouse Model of Alzheimer's Disease Pathology. Chen L, Christenson Wick Z, Vetere LM, Vaughan N, Jurkowski A, Galas A, Diego KS, Philipsberg PA, Soler I, Feng Y, Cai DJ, Shuman T The Journal of neuroscience : the official journal of the Society for Neuroscience 37714705 J Neurosci 2023 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/37714705
A distinct signaling pathway in parvalbumin-positive interneurons controls flexible memory updating. Cai DJ, Shuman T Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 35236915 Neuropsychopharmacology 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35236915
Ensemble-specific deficit in neuronal intrinsic excitability in aged mice. Chen L, Francisco TR, Baggetta AM, Zaki Y, Ramirez S, Clem RL, Shuman T, Cai DJ Neurobiology of aging 36652783 Neurobiol Aging 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/36652783
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Enhancing Precision and Efficiency of Cas9-Mediated Knockin Through Combinatorial Fusions of DNA Repair Proteins. Richardson RR, Steyert M, Khim SN, Crutcher GW, Brandenburg C, Robertson CD, Romanowski AJ, Inen J, Altas B, Poulopoulos A The CRISPR journal 37713292 CRISPR J 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/37713292
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Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory Versus Inhibitory Synapses. Altas B, Tuffy LP, Patrizi A, Dimova K, Soykan T, Brandenburg C, Romanowski AJ, Whitten JR, Robertson CD, Khim SN, Crutcher GW, Ambrozkiewicz MC, Yagensky O, Krueger-Burg D, Hammer M, Hsiao HH, Laskowski PR, Dyck L, Puche AC, Sassoè-Pognetto M, Chua JJE, Urlaub H, Jahn O, Brose N, Poulopoulos A Biological psychiatry 38154503 Biol Psychiatry 2024 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/38154503
Neuronal mTOR Outposts: Implications for Translation, Signaling, and Plasticity. Altas B, Romanowski AJ, Bunce GW, Poulopoulos A Frontiers in cellular neuroscience 35465614 Front Cell Neurosci 2022 https://www.ncbi.nlm.nih.gov/pubmed/35465614
India ink to 3D imaging: The legacy of Dr. Deepak "Dee" N. Pandya and his influence on generations of neuroanatomists. Blatt GJ, Brandenburg C, Poulopoulos A The Journal of comparative neurology 37916788 J Comp Neurol 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37916788
Symmetry in levels of axon-axon homophilic adhesion establishes topography in the corpus callosum and development of connectivity between brain hemispheres. Poulopoulos A, Davis P, Brandenburg C, Itoh Y, Galazo MJ, Greig LC, Romanowski AJ, Budnik B, Macklis JD bioRxiv : the preprint server for biology 38585721 bioRxiv 2024 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/38585721
NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination and seizure threshold. Iffland PH, Everett ME, Cobb-Pitstick KM, Bowser LE, Barnes AE, Babus JK, Romanowski AJ, Baybis M, Elziny S, Puffenberger EG, Gonzaga-Jauregui C, Poulopoulos A, Carson VJ, Crino PB Brain : a journal of neurology 35136953 Brain 2022 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/35136953
The brain's dark transcriptome: Sequencing RNA in distal compartments of neurons and glia. Ament SA, Poulopoulos A Current opinion in neurobiology 37196598 Curr Opin Neurobiol 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37196598
Dysfunctional Cortical Gradient Topography in Treatment-Resistant Major Depressive Disorder. Pasquini L, Fryer SL, Eisendrath SJ, Segal ZV, Lee AJ, Brown JA, Saggar M, Mathalon DH Biological psychiatry. Cognitive neuroscience and neuroimaging 36754677 Biol Psychiatry Cogn Neurosci Neuroimaging 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/36754677
Development of top-down cortical propagations in youth. Pines A, Keller AS, Larsen B, Bertolero M, Ashourvan A, Bassett DS, Cieslak M, Covitz S, Fan Y, Feczko E, Houghton A, Rueter AR, Saggar M, Shafiei G, Tapera TM, Vogel J, Weinstein SM, Shinohara RT, Williams LM, Fair DA, Satterthwaite TD Neuron 36803653 Neuron 2023 Apr 19 https://www.ncbi.nlm.nih.gov/pubmed/36803653
Temporal Mapper: Transition networks in simulated and real neural dynamics. Zhang M, Chowdhury S, Saggar M Network neuroscience (Cambridge, Mass.) 37397880 Netw Neurosci 2023 https://www.ncbi.nlm.nih.gov/pubmed/37397880
Neural resources shift under Methylphenidate: A computational approach to examine anxiety-cognition interplay. Saggar M, Bruno J, Gaillard C, Claudino L, Ernst M NeuroImage 36273770 Neuroimage 2022 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/36273770
Precision dynamical mapping using topological data analysis reveals a hub-like transition state at rest. Saggar M, Shine JM, Liégeois R, Dosenbach NUF, Fair D Nature communications 35970984 Nat Commun 2022 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/35970984
Cross-attractor modeling of resting-state functional connectivity in psychiatric disorders. Sun Y, Zhang M, Saggar M NeuroImage 37579998 Neuroimage 2023 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/37579998
Generating dynamical neuroimaging spatiotemporal representations (DyNeuSR) using topological data analysis. Geniesse C, Sporns O, Petri G, Saggar M Network neuroscience (Cambridge, Mass.) 31410378 Netw Neurosci 2019 https://www.ncbi.nlm.nih.gov/pubmed/31410378
Pushing the Boundaries of Psychiatric Neuroimaging to Ground Diagnosis in Biology. Saggar M, Uddin LQ eNeuro 31685674 eNeuro 2019 Nov/Dec https://www.ncbi.nlm.nih.gov/pubmed/31685674
Deconstructing the Mapper algorithm to extract richer topological and temporal features from functional neuroimaging data. Haşegan D, Geniesse C, Chowdhury S, Saggar M bioRxiv : the preprint server for biology 37904918 bioRxiv 2023 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/37904918
Thalamocortical connectivity is associated with autism symptoms in high-functioning adults with autism and typically developing adults. Ayub R, Sun KL, Flores RE, Lam VT, Jo B, Saggar M, Fung LK Translational psychiatry 33536431 Transl Psychiatry 2021 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/33536431
Increased anti-correlation between the left dorsolateral prefrontal cortex and the default mode network following Stanford Neuromodulation Therapy (SNT): analysis of a double-blinded, randomized, sham-controlled trial. Gajawelli N, Geoly AD, Batail JM, Xiao X, Maron-Katz A, Cole E, Azeez A, Kratter IH, Saggar M, Williams NR Npj mental health research 38971869 Npj Ment Health Res 2024 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/38971869
Network effects of Stanford Neuromodulation Therapy (SNT) in treatment-resistant major depressive disorder: a randomized, controlled trial. Batail JM, Xiao X, Azeez A, Tischler C, Kratter IH, Bishop JH, Saggar M, Williams NR Translational psychiatry 37400432 Transl Psychiatry 2023 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/37400432
Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice. Rosenberg AM, Saggar M, Monzel AS, Devine J, Rogu P, Limoges A, Junker A, Sandi C, Mosharov EV, Dumitriu D, Anacker C, Picard M Nature communications 37563104 Nat Commun 2023 Aug 10 https://www.ncbi.nlm.nih.gov/pubmed/37563104
Cross-attractor repertoire provides new perspective on structure-function relationship in the brain. Zhang M, Sun Y, Saggar M NeuroImage 35732244 Neuroimage 2022 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/35732244
NeuMapper: A scalable computational framework for multiscale exploration of the brain's dynamical organization. Geniesse C, Chowdhury S, Saggar M Network neuroscience (Cambridge, Mass.) 35733428 Netw Neurosci 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35733428
Spontaneous and deliberate modes of creativity: Multitask eigen-connectivity analysis captures latent cognitive modes during creative thinking. Xie H, Beaty RE, Jahanikia S, Geniesse C, Sonalkar NS, Saggar M NeuroImage 34469816 Neuroimage 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34469816
Altered canonical and striatal-frontal resting state functional connectivity in children with pathogenic variants in the Ras/mitogen-activated protein kinase pathway. Bruno JL, Shrestha SB, Reiss AL, Saggar M, Green T Molecular psychiatry 35087195 Mol Psychiatry 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35087195
Densely sampled stimulus-response map of human cortex with single pulse TMS-EEG and its relation to whole brain neuroimaging measures. Sun Y, Lucas MV, Cline CC, Menezes MC, Kim S, Badami FS, Narayan M, Wu W, Daskalakis ZJ, Etkin A, Saggar M bioRxiv : the preprint server for biology 38948696 bioRxiv 2024 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/38948696
Brief intensive social gaze training reorganizes functional brain connectivity in boys with fragile X syndrome. Saggar M, Bruno JL, Hall SS Cerebral cortex (New York, N.Y. : 1991) 36376964 Cereb Cortex 2023 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/36376964
Sex differences in the reward value of familiar mates in prairie voles. Vahaba DM, Halstead ER, Donaldson ZR, Ahern TH, Beery AK Genes, brain, and behavior 35044087 Genes Brain Behav 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35044087
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Prairie vole pair bonding and plasticity of the social brain. Hiura LC, Donaldson ZR Trends in neurosciences 36369029 Trends Neurosci 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36369029
Nucleus accumbens dopamine release reflects the selective nature of pair bonds. Pierce AF, Protter DSW, Watanabe YL, Chapel GD, Cameron RT, Donaldson ZR Current biology : CB 38218185 Curr Biol 2024 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/38218185
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PhAT: A flexible open-source GUI-driven toolkit for photometry analysis. Murphy KZ, Haile E, McTigue A, Pierce AF, Donaldson ZR bioRxiv : the preprint server for biology 36993180 bioRxiv 2023 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/36993180
Neurobiology and treatment advances for prolonged grief disorder. Donaldson ZR, Shear MK Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 37479860 Neuropsychopharmacology 2024 Jan https://www.ncbi.nlm.nih.gov/pubmed/37479860
Prolonged partner separation erodes nucleus accumbens transcriptional signatures of pair bonding in male prairie voles. Sadino JM, Bradeen XG, Kelly CJ, Brusman LE, Walker DM, Donaldson ZR eLife 36852906 Elife 2023 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/36852906
Wireless multilateral devices for optogenetic studies of individual and social behaviors. Yang Y, Wu M, Vázquez-Guardado A, Wegener AJ, Grajales-Reyes JG, Deng Y, Wang T, Avila R, Moreno JA, Minkowicz S, Dumrongprechachan V, Lee J, Zhang S, Legaria AA, Ma Y, Mehta S, Franklin D, Hartman L, Bai W, Han M, Zhao H, Lu W, Yu Y, Sheng X, Banks A, Yu X, Donaldson ZR, Gereau RW 4th, Good CH, Xie Z, Huang Y, Kozorovitskiy Y, Rogers JA Nature neuroscience 33972800 Nat Neurosci 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/33972800
How prior pair-bonding experience affects future bonding behavior in monogamous prairie voles. Harbert KJ, Pellegrini M, Gordon KM, Donaldson ZR Hormones and behavior 32910950 Horm Behav 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/32910950
A neuronal signature for monogamous reunion. Scribner JL, Vance EA, Protter DSW, Sheeran WM, Saslow E, Cameron RT, Klein EM, Jimenez JC, Kheirbek MA, Donaldson ZR Proceedings of the National Academy of Sciences of the United States of America 32381740 Proc Natl Acad Sci U S A 2020 May 19 https://www.ncbi.nlm.nih.gov/pubmed/32381740
Prairie voles as a model for adaptive reward remodeling following loss of a bonded partner. Sadino JM, Donaldson ZR Annals of the New York Academy of Sciences 38594916 Ann N Y Acad Sci 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38594916
PhAT: A Flexible Open-Source GUI-Driven Toolkit for Photometry Analysis. Murphy KZ, Haile ED, McTigue AD, Pierce AF, Donaldson ZR Current protocols 37184156 Curr Protoc 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37184156
Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering. Chen Y, Jang H, Spratt PWE, Kosar S, Taylor DE, Essner RA, Bai L, Leib DE, Kuo TW, Lin YC, Patel M, Subkhangulova A, Kato S, Feinberg EH, Bender KJ, Knight ZA, Garrison JL Neuron 32574560 Neuron 2020 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/32574560
Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration. Cheung V, Chung P, Bjorni M, Shvareva VA, Lopez YC, Feinberg EH Cell reports 34936877 Cell Rep 2021 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/34936877
Hindbrain modules differentially transform activity of single collicular neurons to coordinate movements. Zahler SH, Taylor DE, Wright BS, Wong JY, Shvareva VA, Park YA, Feinberg EH Cell 37343561 Cell 2023 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/37343561
Transcriptional profiling of mouse projection neurons with VECTORseq. Cheung V, Chung P, Feinberg EH STAR protocols 36035788 STAR Protoc 2022 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/36035788
Superior colliculus drives stimulus-evoked directionally biased saccades and attempted head movements in head-fixed mice. Zahler SH, Taylor DE, Wong JY, Adams JM, Feinberg EH eLife 34970968 Elife 2021 Dec 31 https://www.ncbi.nlm.nih.gov/pubmed/34970968
DART.2: bidirectional synaptic pharmacology with thousandfold cellular specificity. Shields BC, Yan H, Lim SSX, Burwell SCV, Cammarata CM, Fleming EA, Yousefzadeh SA, Goldenshtein VZ, Kahuno EW, Vagadia PP, Loughran MH, Zhiquan L, McDonnell ME, Scalabrino ML, Thapa M, Hawley TM, Field GD, Hull C, Schiltz GE, Glickfeld LL, Reitz AB, Tadross MR Nature methods 38877316 Nat Methods 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38877316
Noradrenergic Signaling Disengages Feedforward Transmission in the Nucleus Accumbens Shell. Manz KM, Coleman BC, Grueter CA, Shields BC, Tadross MR, Grueter BA The Journal of neuroscience : the official journal of the Society for Neuroscience 33737458 J Neurosci 2021 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/33737458
Acute restraint stress redirects prefrontal cortex circuit function through mGlu(5) receptor plasticity on somatostatin-expressing interneurons. Joffe ME, Maksymetz J, Luschinger JR, Dogra S, Ferranti AS, Luessen DJ, Gallinger IM, Xiang Z, Branthwaite H, Melugin PR, Williford KM, Centanni SW, Shields BC, Lindsley CW, Calipari ES, Siciliano CA, Niswender CM, Tadross MR, Winder DG, Conn PJ Neuron 35045338 Neuron 2022 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/35045338
Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations. Fleming EA, Field GD, Tadross MR, Hull C Nature neuroscience 38321293 Nat Neurosci 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38321293
Natural phasic inhibition of dopamine neurons signals cognitive rigidity. Burwell SCV, Yan H, Lim SSX, Shields BC, Tadross MR bioRxiv : the preprint server for biology 38766037 bioRxiv 2024 Jul 13 https://www.ncbi.nlm.nih.gov/pubmed/38766037
An open-source transparent microelectrode array. Weaver IA, Li AW, Shields BC, Tadross MR Journal of neural engineering 35349992 J Neural Eng 2022 Apr 13 https://www.ncbi.nlm.nih.gov/pubmed/35349992
Identification of Structural Variation in Chimpanzees Using Optical Mapping and Nanopore Sequencing. Soto DC, Shew C, Mastoras M, Schmidt JM, Sahasrabudhe R, Kaya G, Andrés AM, Dennis MY Genes 32143403 Genes (Basel) 2020 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/32143403
Evaluation of CRISPR gene-editing tools in zebrafish. Uribe-Salazar JM, Kaya G, Sekar A, Weyenberg K, Ingamells C, Dennis MY BMC genomics 34986794 BMC Genomics 2022 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/34986794
A complete reference genome improves analysis of human genetic variation. Aganezov S, Yan SM, Soto DC, Kirsche M, Zarate S, Avdeyev P, Taylor DJ, Shafin K, Shumate A, Xiao C, Wagner J, McDaniel J, Olson ND, Sauria MEG, Vollger MR, Rhie A, Meredith M, Martin S, Lee J, Koren S, Rosenfeld JA, Paten B, Layer R, Chin CS, Sedlazeck FJ, Hansen NF, Miller DE, Phillippy AM, Miga KH, McCoy RC, Dennis MY, Zook JM, Schatz MC Science (New York, N.Y.) 35357935 Science 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35357935
Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes. Shew CJ, Carmona-Mora P, Soto DC, Mastoras M, Roberts E, Rosas J, Jagannathan D, Kaya G, O'Geen H, Dennis MY Molecular biology and evolution 34009325 Mol Biol Evol 2021 Jul 29 https://www.ncbi.nlm.nih.gov/pubmed/34009325
LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons. Libé-Philippot B, Lejeune A, Wierda K, Louros N, Erkol E, Vlaeminck I, Beckers S, Gaspariunaite V, Bilheu A, Konstantoulea K, Nyitrai H, De Vleeschouwer M, Vennekens KM, Vidal N, Bird TW, Soto DC, Jaspers T, Dewilde M, Dennis MY, Rousseau F, Comoletti D, Schymkowitz J, Theys T, de Wit J, Vanderhaeghen P Cell 38134874 Cell 2023 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/38134874
Local genetic adaptation to habitat in wild chimpanzees. Ostridge HJ, Fontsere C, Lizano E, Soto DC, Schmidt JM, Saxena V, Alvarez-Estape M, Barratt CD, Gratton P, Bocksberger G, Lester JD, Dieguez P, Agbor A, Angedakin S, Assumang AK, Bailey E, Barubiyo D, Bessone M, Brazzola G, Chancellor R, Cohen H, Coupland C, Danquah E, Deschner T, Dotras L, Dupain J, Egbe VE, Granjon AC, Head J, Hedwig D, Hermans V, Hernandez-Aguilar RA, Jeffery KJ, Jones S, Junker J, Kadam P, Kaiser M, Kalan AK, Kambere M, Kienast I, Kujirakwinja D, Langergraber KE, Lapuente J, Larson B, Laudisoit A, Lee KC, Llana M, Maretti G, Martín R, Meier A, Morgan D, Neil E, Nicholl S, Nixon S, Normand E, Orbell C, Ormsby LJ, Orume R, Pacheco L, Preece J, Regnaut S, Robbins MM, Rundus A, Sanz C, Sciaky L, Sommer V, Stewart FA, Tagg N, Tédonzong LR, van Schijndel J, Vendras E, Wessling EG, Willie J, Wittig RM, Yuh YG, Yurkiw K, Vigilant L, Piel A, Boesch C, Kühl HS, Dennis MY, Marques-Bonet T, Arandjelovic M, Andrés AM bioRxiv : the preprint server for biology 39026872 bioRxiv 2024 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/39026872
Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development. Uribe-Salazar JM, Kaya G, Weyenberg K, Radke B, Hino K, Soto DC, Shiu JL, Zhang W, Ingamells C, Haghani NK, Xu E, Rosas J, Simó S, Miesfeld J, Glaser T, Baraban SC, Jao LE, Dennis MY bioRxiv : the preprint server for biology 39314374 bioRxiv 2024 Sep 27 https://www.ncbi.nlm.nih.gov/pubmed/39314374
Complete genomic and epigenetic maps of human centromeres. Altemose N, Logsdon GA, Bzikadze AV, Sidhwani P, Langley SA, Caldas GV, Hoyt SJ, Uralsky L, Ryabov FD, Shew CJ, Sauria MEG, Borchers M, Gershman A, Mikheenko A, Shepelev VA, Dvorkina T, Kunyavskaya O, Vollger MR, Rhie A, McCartney AM, Asri M, Lorig-Roach R, Shafin K, Lucas JK, Aganezov S, Olson D, de Lima LG, Potapova T, Hartley GA, Haukness M, Kerpedjiev P, Gusev F, Tigyi K, Brooks S, Young A, Nurk S, Koren S, Salama SR, Paten B, Rogaev EI, Streets A, Karpen GH, Dernburg AF, Sullivan BA, Straight AF, Wheeler TJ, Gerton JL, Eichler EE, Phillippy AM, Timp W, Dennis MY, O'Neill RJ, Zook JM, Schatz MC, Pevzner PA, Diekhans M, Langley CH, Alexandrov IA, Miga KH Science (New York, N.Y.) 35357911 Science 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35357911
Telomere-to-telomere assembly of a complete human X chromosome. Miga KH, Koren S, Rhie A, Vollger MR, Gershman A, Bzikadze A, Brooks S, Howe E, Porubsky D, Logsdon GA, Schneider VA, Potapova T, Wood J, Chow W, Armstrong J, Fredrickson J, Pak E, Tigyi K, Kremitzki M, Markovic C, Maduro V, Dutra A, Bouffard GG, Chang AM, Hansen NF, Wilfert AB, Thibaud-Nissen F, Schmitt AD, Belton JM, Selvaraj S, Dennis MY, Soto DC, Sahasrabudhe R, Kaya G, Quick J, Loman NJ, Holmes N, Loose M, Surti U, Risques RA, Graves Lindsay TA, Fulton R, Hall I, Paten B, Howe K, Timp W, Young A, Mullikin JC, Pevzner PA, Gerton JL, Sullivan BA, Eichler EE, Phillippy AM Nature 32663838 Nature 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32663838
Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. Zhu Y, Gomez JA, Laufer BI, Mordaunt CE, Mouat JS, Soto DC, Dennis MY, Benke KS, Bakulski KM, Dou J, Marathe R, Jianu JM, Williams LA, Gutierrez Fugón OJ, Walker CK, Ozonoff S, Daniels J, Grosvenor LP, Volk HE, Feinberg JI, Fallin MD, Hertz-Picciotto I, Schmidt RJ, Yasui DH, LaSalle JM Genome biology 35168652 Genome Biol 2022 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/35168652
FixItFelix: improving genomic analysis by fixing reference errors. Behera S, LeFaive J, Orchard P, Mahmoud M, Paulin LF, Farek J, Soto DC, Parker SCJ, Smith AV, Dennis MY, Zook JM, Sedlazeck FJ Genome biology 36810122 Genome Biol 2023 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/36810122
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The complete sequence of a human genome. Nurk S, Koren S, Rhie A, Rautiainen M, Bzikadze AV, Mikheenko A, Vollger MR, Altemose N, Uralsky L, Gershman A, Aganezov S, Hoyt SJ, Diekhans M, Logsdon GA, Alonge M, Antonarakis SE, Borchers M, Bouffard GG, Brooks SY, Caldas GV, Chen NC, Cheng H, Chin CS, Chow W, de Lima LG, Dishuck PC, Durbin R, Dvorkina T, Fiddes IT, Formenti G, Fulton RS, Fungtammasan A, Garrison E, Grady PGS, Graves-Lindsay TA, Hall IM, Hansen NF, Hartley GA, Haukness M, Howe K, Hunkapiller MW, Jain C, Jain M, Jarvis ED, Kerpedjiev P, Kirsche M, Kolmogorov M, Korlach J, Kremitzki M, Li H, Maduro VV, Marschall T, McCartney AM, McDaniel J, Miller DE, Mullikin JC, Myers EW, Olson ND, Paten B, Peluso P, Pevzner PA, Porubsky D, Potapova T, Rogaev EI, Rosenfeld JA, Salzberg SL, Schneider VA, Sedlazeck FJ, Shafin K, Shew CJ, Shumate A, Sims Y, Smit AFA, Soto DC, Sović I, Storer JM, Streets A, Sullivan BA, Thibaud-Nissen F, Torrance J, Wagner J, Walenz BP, Wenger A, Wood JMD, Xiao C, Yan SM, Young AC, Zarate S, Surti U, McCoy RC, Dennis MY, Alexandrov IA, Gerton JL, O'Neill RJ, Timp W, Zook JM, Schatz MC, Eichler EE, Miga KH, Phillippy AM Science (New York, N.Y.) 35357919 Science 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35357919
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Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement. Corre J, van Zessen R, Loureiro M, Patriarchi T, Tian L, Pascoli V, Lüscher C eLife 30373717 Elife 2018 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/30373717
An expanded palette of dopamine sensors for multiplex imaging in vivo. Patriarchi T, Mohebi A, Sun J, Marley A, Liang R, Dong C, Puhger K, Mizuno GO, Davis CM, Wiltgen B, von Zastrow M, Berke JD, Tian L Nature methods 32895537 Nat Methods 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/32895537
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Imaging chemical neurotransmission with genetically encoded fluorescent sensors. Liang R, Broussard GJ, Tian L ACS chemical neuroscience 25565280 ACS Chem Neurosci 2015 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/25565280
Maps of neuronal activity across the mouse brain. Andreoni A, Tian L Nature biomedical engineering 31073176 Nat Biomed Eng 2019 May https://www.ncbi.nlm.nih.gov/pubmed/31073176
Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance. Oe Y, Wang X, Patriarchi T, Konno A, Ozawa K, Yahagi K, Hirai H, Tsuboi T, Kitaguchi T, Tian L, McHugh TJ, Hirase H Nature communications 31980655 Nat Commun 2020 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/31980655
An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J Nature chemical biology 32989297 Nat Chem Biol 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/32989297
Imaging voltage and brain chemistry with genetically encoded sensors and modulators. Pal A, Tian L Current opinion in chemical biology 32823064 Curr Opin Chem Biol 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32823064
Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning. Unger EK, Keller JP, Altermatt M, Liang R, Matsui A, Dong C, Hon OJ, Yao Z, Sun J, Banala S, Flanigan ME, Jaffe DA, Hartanto S, Carlen J, Mizuno GO, Borden PM, Shivange AV, Cameron LP, Sinning S, Underhill SM, Olson DE, Amara SG, Temple Lang D, Rudnick G, Marvin JS, Lavis LD, Lester HA, Alvarez VA, Fisher AJ, Prescher JA, Kash TL, Yarov-Yarovoy V, Gradinaru V, Looger LL, Tian L Cell 33333022 Cell 2020 Dec 23 https://www.ncbi.nlm.nih.gov/pubmed/33333022
Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1. Robinson JE, Coughlin GM, Hori AM, Cho JR, Mackey ED, Turan Z, Patriarchi T, Tian L, Gradinaru V eLife 31545171 Elife 2019 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/31545171
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Psychedelic-inspired drug discovery using an engineered biosensor. Dong C, Ly C, Dunlap LE, Vargas MV, Sun J, Hwang IW, Azinfar A, Oh WC, Wetsel WC, Olson DE, Tian L Cell 33915107 Cell 2021 May 13 https://www.ncbi.nlm.nih.gov/pubmed/33915107
Distinct sub-second dopamine signaling in dorsolateral striatum measured by a genetically-encoded fluorescent sensor. Salinas AG, Lee JO, Augustin SM, Zhang S, Patriarchi T, Tian L, Morales M, Mateo Y, Lovinger DM Nature communications 37739964 Nat Commun 2023 Sep 22 https://www.ncbi.nlm.nih.gov/pubmed/37739964
In vivo measurement of afferent activity with axon-specific calcium imaging. Broussard GJ, Liang Y, Fridman M, Unger EK, Meng G, Xiao X, Ji N, Petreanu L, Tian L Nature neuroscience 30127424 Nat Neurosci 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30127424
Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model. Mizuno GO, Wang Y, Shi G, Wang Y, Sun J, Papadopoulos S, Broussard GJ, Unger EK, Deng W, Weick J, Bhattacharyya A, Chen CY, Yu G, Looger LL, Tian L Cell reports 29996097 Cell Rep 2018 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/29996097
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New dimensions and new tools to realize the potential of RDoC: digital phenotyping via smartphones and connected devices. Torous J, Onnela JP, Keshavan M Translational psychiatry 28267146 Transl Psychiatry 2017 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/28267146
Inferring mobility measures from GPS traces with missing data. Barnett I, Onnela JP Biostatistics (Oxford, England) 30371736 Biostatistics 2020 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/30371736
Smartphone-based Assessment of Preoperative Decision Conflict and Postoperative Physical Activity Among Patients Undergoing Cancer Surgery: A Prospective Cohort Study. Panda N, Solsky I, Cauley CE, Lipsitz S, Desai EV, Huang EJ, Benjamin EM, Lubitz CC, Onnela JP, Haynes AB Annals of surgery 32941270 Ann Surg 2022 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/32941270
Smartphone Global Positioning System (GPS) Data Enhances Recovery Assessment After Breast Cancer Surgery. Panda N, Solsky I, Hawrusik B, Liu G, Reeder H, Lipsitz S, Desai EV, Lowery KW, Miller K, Gadd MA, Lubitz CC, Smith BL, Specht M, Onnela JP, Haynes AB Annals of surgical oncology 32812109 Ann Surg Oncol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/32812109
A comparison of passive and active estimates of sleep in a cohort with schizophrenia. Staples P, Torous J, Barnett I, Carlson K, Sandoval L, Keshavan M, Onnela JP NPJ schizophrenia 29038553 NPJ Schizophr 2017 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/29038553
A crossroad for validating digital tools in schizophrenia and mental health. Torous J, Staples P, Barnett I, Onnela JP, Keshavan M NPJ schizophrenia 29626190 NPJ Schizophr 2018 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/29626190
Augmented Movelet Method for Activity Classification Using Smartphone Gyroscope and Accelerometer Data. Huang EJ, Onnela JP Sensors (Basel, Switzerland) 32630752 Sensors (Basel) 2020 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/32630752
Digital Phenotyping to Quantify Psychosocial Well-Being Trajectories After Spinal Cord Injury. Mercier HW, Hamner JW, Torous J, Onnela JP, Taylor JA American journal of physical medicine & rehabilitation 32576743 Am J Phys Med Rehabil 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32576743
Sociodemographic characteristics of missing data in digital phenotyping. Kiang MV, Chen JT, Krieger N, Buckee CO, Alexander MJ, Baker JT, Buckner RL, Coombs G 3rd, Rich-Edwards JW, Carlson KW, Onnela JP Scientific reports 34326370 Sci Rep 2021 Jul 29 https://www.ncbi.nlm.nih.gov/pubmed/34326370
Open-source Longitudinal Sleep Analysis From Accelerometer Data (DPSleep): Algorithm Development and Validation. Rahimi-Eichi H, Coombs Iii G, Vidal Bustamante CM, Onnela JP, Baker JT, Buckner RL JMIR mHealth and uHealth 34612831 JMIR Mhealth Uhealth 2021 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/34612831
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Fluctuations in behavior and affect in college students measured using deep phenotyping. Vidal Bustamante CM, Coombs G 3rd, Rahimi-Eichi H, Mair P, Onnela JP, Baker JT, Buckner RL Scientific reports 35121741 Sci Rep 2022 Feb 4 https://www.ncbi.nlm.nih.gov/pubmed/35121741
Estimating longitudinal depressive symptoms from smartphone data in a transdiagnostic cohort. Pellegrini AM, Huang EJ, Staples PC, Hart KL, Lorme JM, Brown HE, Perlis RH, Onnela JJ Brain and behavior 35076166 Brain Behav 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/35076166
The relationship of rate and pause features to the communicative participation of people living with ALS. Connaghan KP, Green JR, Eshghi M, Haenssler AE, Scheier ZA, Clark A, Iyer A, Richburg BD, Rowe HP, Okada J, Johnson SA, Onnela JP, Burke KM, Berry JD Muscle & nerve 38837773 Muscle Nerve 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38837773
Determining sample size and length of follow-up for smartphone-based digital phenotyping studies. Barnett I, Torous J, Reeder HT, Baker J, Onnela JP Journal of the American Medical Informatics Association : JAMIA 33043370 J Am Med Inform Assoc 2020 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/33043370
High potential but limited evidence: Using voice data from smartphones to monitor and diagnose mood disorders. Or F, Torous J, Onnela JP Psychiatric rehabilitation journal 28891659 Psychiatr Rehabil J 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/28891659
Characterizing the clinical relevance of digital phenotyping data quality with applications to a cohort with schizophrenia. Torous J, Staples P, Barnett I, Sandoval LR, Keshavan M, Onnela JP NPJ digital medicine 31304300 NPJ Digit Med 2018 https://www.ncbi.nlm.nih.gov/pubmed/31304300
Beyond smartphones and sensors: choosing appropriate statistical methods for the analysis of longitudinal data. Barnett I, Torous J, Staples P, Keshavan M, Onnela JP Journal of the American Medical Informatics Association : JAMIA 30272176 J Am Med Inform Assoc 2018 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/30272176
Realizing the potential of mobile mental health: new methods for new data in psychiatry. Torous J, Staples P, Onnela JP Current psychiatry reports 26073363 Curr Psychiatry Rep 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26073363
New Tools for New Research in Psychiatry: A Scalable and Customizable Platform to Empower Data Driven Smartphone Research. Torous J, Kiang MV, Lorme J, Onnela JP JMIR mental health 27150677 JMIR Ment Health 2016 May 5 https://www.ncbi.nlm.nih.gov/pubmed/27150677
Smartphone-Based Tracking of Sleep in Depression, Anxiety, and Psychotic Disorders. Aledavood T, Torous J, Triana Hoyos AM, Naslund JA, Onnela JP, Keshavan M Current psychiatry reports 31161412 Curr Psychiatry Rep 2019 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/31161412
Precision Assessment of Real-World Associations Between Stress and Sleep Duration Using Actigraphy Data Collected Continuously for an Academic Year: Individual-Level Modeling Study. Vidal Bustamante CM, Coombs Iii G, Rahimi-Eichi H, Mair P, Onnela JP, Baker JT, Buckner RL JMIR formative research 38687600 JMIR Form Res 2024 Apr 30 https://www.ncbi.nlm.nih.gov/pubmed/38687600
Utilizing a Personal Smartphone Custom App to Assess the Patient Health Questionnaire-9 (PHQ-9) Depressive Symptoms in Patients With Major Depressive Disorder. Torous J, Staples P, Shanahan M, Lin C, Peck P, Keshavan M, Onnela JP JMIR mental health 26543914 JMIR Ment Health 2015 Jan-Mar https://www.ncbi.nlm.nih.gov/pubmed/26543914
EndNote: Feature-based classification of networks. Barnett I, Malik N, Kuijjer ML, Mucha PJ, Onnela JP Network science (Cambridge University Press) 31984135 Netw Sci (Camb Univ Press) 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31984135
Expected Versus Experienced Health-Related Quality of Life Among Patients Recovering From Cancer Surgery: A Prospective Cohort Study. Panda N, Solsky I, Neal BJ, Hawrusik B, Lipsitz S, Lubitz CC, Gibbons C, Brindle M, Sinyard RD, Onnela JP, Cauley CE, Haynes AB Annals of surgery open : perspectives of surgical history, education, and clinical approaches 34179891 Ann Surg Open 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34179891
Understanding the quality, effectiveness and attributes of top-rated smartphone health apps. Wisniewski H, Liu G, Henson P, Vaidyam A, Hajratalli NK, Onnela JP, Torous J Evidence-based mental health 30635262 Evid Based Ment Health 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30635262
The HOPE Pilot Study: Harnessing Patient-Reported Outcomes and Biometric Data to Enhance Cancer Care. Wright AA, Raman N, Staples P, Schonholz S, Cronin A, Carlson K, Keating NL, Onnela JP JCO clinical cancer informatics 30652585 JCO Clin Cancer Inform 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30652585
Design and results of a smartphone-based digital phenotyping study to quantify ALS progression. Berry JD, Paganoni S, Carlson K, Burke K, Weber H, Staples P, Salinas J, Chan J, Green JR, Connaghan K, Barback J, Onnela JP Annals of clinical and translational neurology 31139685 Ann Clin Transl Neurol 2019 May https://www.ncbi.nlm.nih.gov/pubmed/31139685
Relapse prediction in schizophrenia through digital phenotyping: a pilot study. Barnett I, Torous J, Staples P, Sandoval L, Keshavan M, Onnela JP Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 29511333 Neuropsychopharmacology 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29511333
Methodology and Reporting of Mobile Heath and Smartphone Application Studies for Schizophrenia. Torous J, Firth J, Mueller N, Onnela JP, Baker JT Harvard review of psychiatry 28234658 Harv Rev Psychiatry 2017 May/Jun https://www.ncbi.nlm.nih.gov/pubmed/28234658
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Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion. Meda KS, Patel T, Braz JM, Malik R, Turner ML, Seifikar H, Basbaum AI, Sohal VS Neuron 31030955 Neuron 2019 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/31030955
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The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles. Vogt D, Cho KKA, Lee AT, Sohal VS, Rubenstein JLR Cell reports 25937288 Cell Rep 2015 May 12 https://www.ncbi.nlm.nih.gov/pubmed/25937288
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Interneuron Transplantation Rescues Social Behavior Deficits without Restoring Wild-Type Physiology in a Mouse Model of Autism with Excessive Synaptic Inhibition. Southwell DG, Seifikar H, Malik R, Lavi K, Vogt D, Rubenstein JL, Sohal VS The Journal of neuroscience : the official journal of the Society for Neuroscience 31988060 J Neurosci 2020 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/31988060
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Roles of Prefrontal Cortex and Mediodorsal Thalamus in Task Engagement and Behavioral Flexibility. Marton TF, Seifikar H, Luongo FJ, Lee AT, Sohal VS The Journal of neuroscience : the official journal of the Society for Neuroscience 29437889 J Neurosci 2018 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/29437889
Putative Microcircuit-Level Substrates for Attention Are Disrupted in Mouse Models of Autism. Luongo FJ, Horn ME, Sohal VS Biological psychiatry 26022075 Biol Psychiatry 2016 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/26022075
Resolving the 22q11.2 deletion using CTLR-Seq reveals chromosomal rearrangement mechanisms and individual variance in breakpoints. Zhou B, Purmann C, Guo H, Shin G, Huang Y, Pattni R, Meng Q, Greer SU, Roychowdhury T, Wood RN, Ho M, Dohna HZ, Abyzov A, Hallmayer JF, Wong WH, Ji HP, Urban AE Proceedings of the National Academy of Sciences of the United States of America 39042694 Proc Natl Acad Sci U S A 2024 Jul 30 https://www.ncbi.nlm.nih.gov/pubmed/39042694
Comprehensive performance comparison of high-resolution array platforms for genome-wide Copy Number Variation (CNV) analysis in humans. Haraksingh RR, Abyzov A, Urban AE BMC genomics 28438122 BMC Genomics 2017 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/28438122
Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders. Li J, Ma Z, Shi M, Malty RH, Aoki H, Minic Z, Phanse S, Jin K, Wall DP, Zhang Z, Urban AE, Hallmayer J, Babu M, Snyder M Cell systems 26949739 Cell Syst 2015 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/26949739
Network Effects of the 15q13.3 Microdeletion on the Transcriptome and Epigenome in Human-Induced Neurons. Zhang S, Zhang X, Purmann C, Ma S, Shrestha A, Davis KN, Ho M, Huang Y, Pattni R, Wong WH, Bernstein JA, Hallmayer J, Urban AE Biological psychiatry 32919612 Biol Psychiatry 2021 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/32919612
Local and global chromatin interactions are altered by large genomic deletions associated with human brain development. Zhang X, Zhang Y, Zhu X, Purmann C, Haney MS, Ward T, Khechaduri A, Yao J, Weissman SM, Urban AE Nature communications 30559385 Nat Commun 2018 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/30559385
Mutations in human DNA methyltransferase DNMT1 induce specific genome-wide epigenomic and transcriptomic changes in neurodevelopment. Davis KN, Qu PP, Ma S, Lin L, Plastini M, Dahl N, Plazzi G, Pizza F, O'Hara R, Wong WH, Hallmayer J, Mignot E, Zhang X, Urban AE Human molecular genetics 37584462 Hum Mol Genet 2023 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/37584462
Seizure Action Plans Do Not Reduce Health Care Utilization in Pediatric Epilepsy Patients. Roundy LM, Filloux FM, Kerr L, Rimer A, Bonkowsky JL Journal of child neurology 26245799 J Child Neurol 2016 Mar https://www.ncbi.nlm.nih.gov/pubmed/26245799
Targeted leukodystrophy diagnosis based on charges and yields for testing. Richards J, Korgenski EK, Taft RJ, Vanderver A, Bonkowsky JL American journal of medical genetics. Part A 26183797 Am J Med Genet A 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26183797
Revised consensus statement on the preventive and symptomatic care of patients with leukodystrophies. Adang LA, Sherbini O, Ball L, Bloom M, Darbari A, Amartino H, DiVito D, Eichler F, Escolar M, Evans SH, Fatemi A, Fraser J, Hollowell L, Jaffe N, Joseph C, Karpinski M, Keller S, Maddock R, Mancilla E, McClary B, Mertz J, Morgart K, Langan T, Leventer R, Parikh S, Pizzino A, Prange E, Renaud DL, Rizzo W, Shapiro J, Suhr D, Suhr T, Tonduti D, Waggoner J, Waldman A, Wolf NI, Zerem A, Bonkowsky JL, Bernard G, van Haren K, Vanderver A, Global Leukodystrophy Initiative (GLIA) Consortium Molecular genetics and metabolism 28863857 Mol Genet Metab 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/28863857
A zebrafish model of X-linked adrenoleukodystrophy recapitulates key disease features and demonstrates a developmental requirement for abcd1 in oligodendrocyte patterning and myelination. Strachan LR, Stevenson TJ, Freshner B, Keefe MD, Miranda Bowles D, Bonkowsky JL Human molecular genetics 28911205 Hum Mol Genet 2017 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/28911205
National variation in costs and mortality for leukodystrophy patients in US children's hospitals. Brimley CJ, Lopez J, van Haren K, Wilkes J, Sheng X, Nelson C, Korgenski EK, Srivastava R, Bonkowsky JL Pediatric neurology 23953952 Pediatr Neurol 2013 Sep https://www.ncbi.nlm.nih.gov/pubmed/23953952
Autism Spectrum Disorder and Neonatal Serum Magnesium Levels in Preterm Infants. Bakian AV, Bilder DA, Korgenski EK, Bonkowsky JL Child neurology open 30246047 Child Neurol Open 2018 https://www.ncbi.nlm.nih.gov/pubmed/30246047
A Serotonin Circuit Acts as an Environmental Sensor to Mediate Midline Axon Crossing through EphrinB2. Xing L, Son JH, Stevenson TJ, Lillesaar C, Bally-Cuif L, Dahl T, Bonkowsky JL The Journal of neuroscience : the official journal of the Society for Neuroscience 26538650 J Neurosci 2015 Nov 4 https://www.ncbi.nlm.nih.gov/pubmed/26538650
The Midline Axon Crossing Decision Is Regulated through an Activity-Dependent Mechanism by the NMDA Receptor. Gao J, Stevenson TJ, Douglass AD, Barrios JP, Bonkowsky JL eNeuro 29766040 eNeuro 2018 Mar-Apr https://www.ncbi.nlm.nih.gov/pubmed/29766040
Intrapartum magnesium sulfate and the potential for cardiopulmonary drug-drug interactions. Campbell SC, Stockmann C, Balch A, Clark EA, Kamyar M, Varner M, Korgenski EK, Bonkowsky JL, Spigarelli MG, Sherwin CM Therapeutic drug monitoring 24487252 Ther Drug Monit 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24487252
Neonatal magnesium levels correlate with motor outcomes in premature infants: a long-term retrospective cohort study. Doll E, Wilkes J, Cook LJ, Korgenski EK, Faix RG, Yoder BA, Srivastava R, Sherwin CM, Spigarelli MG, Clark EA, Bonkowsky JL Frontiers in pediatrics 25414842 Front Pediatr 2014 https://www.ncbi.nlm.nih.gov/pubmed/25414842
Temporal Dysynchrony in brain connectivity gene expression following hypoxia. Milash B, Gao J, Stevenson TJ, Son JH, Dahl T, Bonkowsky JL BMC genomics 27146468 BMC Genomics 2016 May 4 https://www.ncbi.nlm.nih.gov/pubmed/27146468
An automated system for rapid cellular extraction from live zebrafish embryos and larvae: Development and application to genotyping. Lambert CJ, Freshner BC, Chung A, Stevenson TJ, Bowles DM, Samuel R, Gale BK, Bonkowsky JL PloS one 29543903 PLoS One 2018 https://www.ncbi.nlm.nih.gov/pubmed/29543903
The conserved dopaminergic diencephalospinal tract mediates vertebrate locomotor development in zebrafish larvae. Lambert AM, Bonkowsky JL, Masino MA The Journal of neuroscience : the official journal of the Society for Neuroscience 23015438 J Neurosci 2012 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/23015438
Neurodegeneration in a Drosophila model of adrenoleukodystrophy: the roles of the Bubblegum and Double bubble acyl-CoA synthetases. Sivachenko A, Gordon HB, Kimball SS, Gavin EJ, Bonkowsky JL, Letsou A Disease models & mechanisms 26893370 Dis Model Mech 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26893370
Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Schweitzer J, Löhr H, Bonkowsky JL, Hübscher K, Driever W Development (Cambridge, England) 23222439 Development 2013 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/23222439
Rapid and efficient zebrafish genotyping using PCR with high-resolution melt analysis. Xing L, Quist TS, Stevenson TJ, Dahlem TJ, Bonkowsky JL Journal of visualized experiments : JoVE 24561516 J Vis Exp 2014 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/24561516
Determinants of health care use in a population-based leukodystrophy cohort. Nelson C, Mundorff MB, Korgenski EK, Brimley CJ, Srivastava R, Bonkowsky JL The Journal of pediatrics 23069195 J Pediatr 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23069195
Expression of arginine vasotocin receptors in the developing zebrafish CNS. Iwasaki K, Taguchi M, Bonkowsky JL, Kuwada JY Gene expression patterns : GEP 23830982 Gene Expr Patterns 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/23830982
Neonatal Magnesium Levels Between 24 and 48 Hours of Life and Outcomes for Epilepsy and Motor Impairment in Premature Infants. Ostrander B, Bardsley T, Korgenski EK, Greene T, Bonkowsky JL Pediatric neurology 27025188 Pediatr Neurol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27025188
Transgenic FingRs for Live Mapping of Synaptic Dynamics in Genetically-Defined Neurons. Son JH, Keefe MD, Stevenson TJ, Barrios JP, Anjewierden S, Newton JB, Douglass AD, Bonkowsky JL Scientific reports 26728131 Sci Rep 2016 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/26728131
A Novel Developmental Role for Dopaminergic Signaling to Specify Hypothalamic Neurotransmitter Identity. Chen YC, Semenova S, Rozov S, Sundvik M, Bonkowsky JL, Panula P The Journal of biological chemistry 27539857 J Biol Chem 2016 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/27539857
Chiari I Malformation Causing Developmental Regression in a 4 Month Old. Doll ES, Bonkowsky JL, Brown LL, de Havenon AH, Brockmeyer DL, Glasgow TS, Morita DC Global pediatric health 27335920 Glob Pediatr Health 2014 https://www.ncbi.nlm.nih.gov/pubmed/27335920
Whole-genome analysis for effective clinical diagnosis and gene discovery in early infantile epileptic encephalopathy. Ostrander BEP, Butterfield RJ, Pedersen BS, Farrell AJ, Layer RM, Ward A, Miller C, DiSera T, Filloux FM, Candee MS, Newcomb T, Bonkowsky JL, Marth GT, Quinlan AR NPJ genomic medicine 30109124 NPJ Genom Med 2018 https://www.ncbi.nlm.nih.gov/pubmed/30109124
Rapid clinical diagnostic variant investigation of genomic patient sequencing data with iobio web tools. Ward A, Karren MA, Di Sera T, Miller C, Velinder M, Qiao Y, Filloux FM, Ostrander B, Butterfield R, Bonkowsky JL, Dere W, Marth GT Journal of clinical and translational science 29707261 J Clin Transl Sci 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/29707261
Costs of the diagnostic odyssey in children with inherited leukodystrophies. Richards J, Korgenski EK, Srivastava R, Bonkowsky JL Neurology 26320197 Neurology 2015 Sep 29 https://www.ncbi.nlm.nih.gov/pubmed/26320197
Motor Behavior Mediated by Continuously Generated Dopaminergic Neurons in the Zebrafish Hypothalamus Recovers after Cell Ablation. McPherson AD, Barrios JP, Luks-Morgan SJ, Manfredi JP, Bonkowsky JL, Douglass AD, Dorsky RI Current biology : CB 26774784 Curr Biol 2016 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/26774784
Maternal magnesium sulphate exposure predicts neonatal magnesium blood concentrations. Sherwin CM, Balch A, Campbell SC, Fredrickson J, Clark EA, Varner M, Stockmann C, Korgenski EK, Bonkowsky JL, Spigarelli MG Basic & clinical pharmacology & toxicology 24164968 Basic Clin Pharmacol Toxicol 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24164968
Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis. Butterfield RJ, Stevenson TJ, Xing L, Newcomb TM, Nelson B, Zeng W, Li X, Lu HM, Lu H, Farwell Gonzalez KD, Wei JP, Chao EC, Prior TW, Snyder PJ, Bonkowsky JL, Swoboda KJ Neurology 24647030 Neurology 2014 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/24647030
Clinical exome sequencing identifies a novel TUBB4A mutation in a child with static hypomyelinating leukodystrophy. Purnell SM, Bleyl SB, Bonkowsky JL Pediatric neurology 24742798 Pediatr Neurol 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24742798
Preventable Infections in Children with Leukodystrophy. Anderson HM, Wilkes J, Korgenski EK, Pulsipher MA, Blaschke AJ, Hersh AL, Srivastava R, Bonkowsky JL Annals of clinical and translational neurology 24955379 Ann Clin Transl Neurol 2014 May 1 https://www.ncbi.nlm.nih.gov/pubmed/24955379
Microfluidic-aided genotyping of zebrafish in the first 48 h with 100% viability. Samuel R, Stephenson R, Roy P, Pryor R, Zhou L, Bonkowsky JL, Gale BK Biomedical microdevices 25773537 Biomed Microdevices 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25773537
Dopaminergic Co-Regulation of Locomotor Development and Motor Neuron Synaptogenesis is Uncoupled by Hypoxia in Zebrafish. Son JH, Stevenson TJ, Bowles MD, Scholl EA, Bonkowsky JL eNeuro 32001551 eNeuro 2020 Jan/Feb https://www.ncbi.nlm.nih.gov/pubmed/32001551
Hypothalamic radial glia function as self-renewing neural progenitors in the absence of Wnt/β-catenin signaling. Duncan RN, Xie Y, McPherson AD, Taibi AV, Bonkowsky JL, Douglass AD, Dorsky RI Development (Cambridge, England) 26603385 Development 2016 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/26603385
Disease specific therapies in leukodystrophies and leukoencephalopathies. Helman G, Van Haren K, Bonkowsky JL, Bernard G, Pizzino A, Braverman N, Suhr D, Patterson MC, Ali Fatemi S, Leonard J, van der Knaap MS, Back SA, Damiani S, Goldman SA, Takanohashi A, Petryniak M, Rowitch D, Messing A, Wrabetz L, Schiffmann R, Eichler F, Escolar ML, Vanderver A, GLIA Consortium Molecular genetics and metabolism 25684057 Mol Genet Metab 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25684057
Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP(+) exposure. Dukes AA, Bai Q, Van Laar VS, Zhou Y, Ilin V, David CN, Agim ZS, Bonkowsky JL, Cannon JR, Watkins SC, Croix CM, Burton EA, Berman SB Neurobiology of disease 27452482 Neurobiol Dis 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27452482
The impact of the COVID-19 pandemic on patients' experiences obtaining a tuberculosis diagnosis in Peru: a mixed-methods study. Millones AK, Lecca L, Acosta D, Campos H, Del Águila-Rojas E, Farroñay S, Morales G, Ramirez-Sandoval J, Torres I, Jimenez J, Yuen CM BMC infectious diseases 36352374 BMC Infect Dis 2022 Nov 9 https://www.ncbi.nlm.nih.gov/pubmed/36352374
Identifying barriers and facilitators to implementation of community-based tuberculosis active case finding with mobile X-ray units in Lima, Peru: a RE-AIM evaluation. Yuen CM, Puma D, Millones AK, Galea JT, Tzelios C, Calderon RI, Brooks MB, Jimenez J, Contreras C, Nichols TC, Nicholson T, Lecca L, Becerra MC, Keshavjee S BMJ open 34234000 BMJ Open 2021 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/34234000
Geospatial analysis of reported activity locations to identify sites for tuberculosis screening. Yuen CM, Brooks MB, Millones AK, Acosta D, Del Águila-Rojas E, Campos H, Farroñay S, Morales G, Ramirez-Sandoval J, Nichols TC, Jimenez J, Jenkins HE, Lecca L Scientific reports 35982104 Sci Rep 2022 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/35982104
A role for community-level socioeconomic indicators in targeting tuberculosis screening interventions. Brooks MB, Jenkins HE, Puma D, Tzelios C, Millones AK, Jimenez J, Galea JT, Lecca L, Becerra MC, Keshavjee S, Yuen CM Scientific reports 35039612 Sci Rep 2022 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/35039612
Adapting a mobile TB screening unit to provide integrated screening services and linkage to primary care. Millones AK, Cohen S, Acosta D, Campos H, Condeso A, Farroñay S, Torres I, Vargas C, Abanto K, Contreras C, Palomino S, Jimenez J, Lecca L, Yuen CM Public health action 39618835 Public Health Action 2024 Dec https://www.ncbi.nlm.nih.gov/pubmed/39618835
Person-centered strategies for delivering TB diagnostic services in Lima, Peru. Yuen CM, Millones AK, Acosta D, Torres I, Farroñay S, Jimenez J, Lecca L Public health action 37736576 Public Health Action 2023 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/37736576
Exploring the role of the private sector in tuberculosis detection and management in Lima, Peru: a mixed-methods patient pathway analysis. Wippel C, Farroñay S, Gilbert HN, Millones AK, Acosta D, Torres I, Jimenez J, Lecca L, Yuen CM medRxiv : the preprint server for health sciences 37808756 medRxiv 2023 Sep 29 https://www.ncbi.nlm.nih.gov/pubmed/37808756
Geographic accessibility to health facilities predicts uptake of community-based tuberculosis screening in an urban setting. Jenkins HE, Ayuk S, Puma D, Brooks MB, Millones AK, Jimenez J, Lecca L, Galea JT, Becerra M, Keshavjee S, Yuen CM International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 35470023 Int J Infect Dis 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35470023
Utility of Mycobacterium tuberculosis Genome Sequencing Snapshots to Assess Transmission Dynamics Over Time. Yuen CM, Huang CC, Millones AK, Calderon RI, Manson AL, Jimenez J, Contreras C, Earl AM, Becerra MC, Lecca L, Murray MB The Journal of infectious diseases 37995298 J Infect Dis 2024 May 15 https://www.ncbi.nlm.nih.gov/pubmed/37995298
Impact of the private sector on spatial accessibility to chest radiography services in Lima, Peru. Xiong Y, Millones AK, Farroñay S, Torres I, Acosta D, Jordan DR, Jimenez J, Wippel C, Jenkins HE, Lecca L, Yuen CM IJTLD open 38698907 IJTLD Open 2024 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/38698907
Barriers and facilitators to tuberculosis diagnosis in Lima, Peru: a mixed methods study. Geadas C, Millones AK, Acosta D, Campos H, Del Aguila-Rojas E, Farroñay S, Morales G, Ramirez-Sandoval J, Torres I, Jimenez J, Lecca L, Yuen CM BMC infectious diseases 39118040 BMC Infect Dis 2024 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/39118040
Mapping local hot spots with routine tuberculosis data: A pragmatic approach to identify spatial variability. Brooks MB, Millones AK, Puma D, Contreras C, Jimenez J, Tzelios C, Jenkins HE, Yuen CM, Keshavjee S, Lecca L, Becerra MC PloS one 35324987 PLoS One 2022 https://www.ncbi.nlm.nih.gov/pubmed/35324987
Closing delivery gaps in the treatment of tuberculosis infection: Lessons from implementation research in Peru. Yuen CM, Millones AK, Puma D, Jimenez J, Galea JT, Calderon R, Pages GS, Brooks MB, Lecca L, Nicholson T, Becerra MC, Keshavjee S PloS one 33606824 PLoS One 2021 https://www.ncbi.nlm.nih.gov/pubmed/33606824
Toward patient-centered tuberculosis preventive treatment: preferences for regimens and formulations in Lima, Peru. Yuen CM, Millones AK, Galea JT, Puma D, Jimenez J, Lecca L, Becerra MC, Keshavjee S BMC public health 33430823 BMC Public Health 2021 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/33430823
Exploring the Role of the Private Sector in Tuberculosis Detection and Management in Lima, Peru: A Mixed-Methods Patient Pathway Analysis. Wippel C, Farroñay S, Gilbert HN, Millones AK, Acosta D, Torres I, Jimenez J, Alarcón VA, Lecca L, Yuen CM The American journal of tropical medicine and hygiene 38744270 Am J Trop Med Hyg 2024 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/38744270
Preventive parenting intervention during childhood and young black adults' unhealthful behaviors: a randomized controlled trial. Brody GH, Yu T, Miller GE, Ehrlich KB, Chen E Journal of child psychology and psychiatry, and allied disciplines 30203840 J Child Psychol Psychiatry 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30203840
Attachment and psychoneuroimmunology. Ehrlich KB Current opinion in psychology 29631123 Curr Opin Psychol 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/29631123
Maltreatment exposure across childhood and low-grade inflammation: Considerations of exposure type, timing, and sex differences. Ehrlich KB, Miller GE, Rogosch FA, Cicchetti D Developmental psychobiology 32896910 Dev Psychobiol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/32896910
Beyond Early Adversity: The Role of Parenting in Infant Physical Health. Stern JA, Beijers R, Ehrlich KB, Cassidy J, de Weerth C Journal of developmental and behavioral pediatrics : JDBP 32271266 J Dev Behav Pediatr 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32271266
Emotional Distress, Targeted Rejection, and Antibody Production After Influenza Vaccination in Adolescence. Corallo KL, Lyle SM, Carlock MA, Ross TM, Ehrlich KB Psychosomatic medicine 35100185 Psychosom Med 2022 May 1 https://www.ncbi.nlm.nih.gov/pubmed/35100185
A preliminary investigation of attachment style and inflammation in African-American young adults. Ehrlich KB, Stern JA, Eccles J, Dinh JV, Hopper EA, Kemeny ME, Adam EK, Cassidy J Attachment & human development 30406721 Attach Hum Dev 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30406721
Exposure to parental depression in adolescence and proinflammatory phenotypes 20 years later. Ehrlich KB, Celia-Sanchez ML, Yu T, Heard-Garris N, Chen E, Miller GE, Brody GH Brain, behavior, and immunity 38242368 Brain Behav Immun 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38242368
How does the social world shape health across the lifespan? Insights and new directions. Ehrlich KB The American psychologist 33382288 Am Psychol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33382288
The Profundity of the Everyday: Family Routines in Adolescence Predict Development in Young Adulthood. Barton AW, Brody GH, Yu T, Kogan SM, Chen E, Ehrlich KB The Journal of adolescent health : official publication of the Society for Adolescent Medicine 30392861 J Adolesc Health 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30392861
Recalled Neighborhood Environments, Parental Control, and Cytokine-Mediated Response to Viral Challenge. Corallo KL, Lyle SM, Murphy MLM, vanDellen MR, Ehrlich KB Psychosomatic medicine 34334728 Psychosom Med 2021 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/34334728
Neighborhood poverty, allostatic load, and changes in cellular aging in African American young adults: the moderating role of attachment. Ehrlich KB, Yu T, Sadiq A, Brody GH Attachment & human development 34617499 Attach Hum Dev 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/34617499
Changes in depressive symptoms and antibody production following influenza vaccination in adolescents and adults. Ehrlich KB, Lyle SM, Corallo KL, Lavner JA, Ross TM Vaccine 38702230 Vaccine 2024 Jun 11 https://www.ncbi.nlm.nih.gov/pubmed/38702230
The protective role of parental vigilance in the link between risky childhood environments and health. Corallo KL, Carr CP, Lavner JA, Koss KJ, Ehrlich KB Social science & medicine (1982) 36527897 Soc Sci Med 2023 Jan https://www.ncbi.nlm.nih.gov/pubmed/36527897
Attachment and physical health: introduction to the special issue. B Ehrlich K, Cassidy J Attachment & human development 30406722 Attach Hum Dev 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30406722
Harsh parenting and youth systemic inflammation: Modulation by the autonomic nervous system. Oshri A, Duprey EB, Liu S, Ehrlich KB Health psychology : official journal of the Division of Health Psychology, American Psychological Association 32202827 Health Psychol 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32202827
Socioeconomic disadvantage and high-effort coping in childhood: evidence of skin-deep resilience. Ehrlich KB, Lyle SM, Corallo KL, Brisson JM, Wiggins ER, Yu T, Chen E, Miller GE, Brody GH Journal of child psychology and psychiatry, and allied disciplines 37246563 J Child Psychol Psychiatry 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/37246563
The benefits of nurturant-involved parenting for children's internalizing symptoms and cardiometabolic health in high-risk contexts. Wiggins ER, Brisson JM, Lavner JA, Ehrlich KB Development and psychopathology 37386849 Dev Psychopathol 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37386849
CAUSAL INFERENCE IN THE CONTEXT OF AN ERROR PRONE EXPOSURE: AIR POLLUTION AND MORTALITY. Wu X, Braun D, Kioumourtzoglou MA, Choirat C, Di Q, Dominici F The annals of applied statistics 31649797 Ann Appl Stat 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/31649797
Machine Learning for Prediction in Electronic Health Data. Rose S JAMA network open 30646089 JAMA Netw Open 2018 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/30646089
Intersections of machine learning and epidemiological methods for health services research. Rose S International journal of epidemiology 32236476 Int J Epidemiol 2021 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/32236476
High-Dimensional Confounding Adjustment Using Continuous Spike and Slab Priors. Antonelli J, Parmigiani G, Dominici F Bayesian analysis 32431779 Bayesian Anal 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/32431779
Considerations Across Three Cultures: Parametric Regressions, Interpretable Algorithms, and Complex Algorithms. Eloyan A, Rose S Observational studies 34485997 Obs Stud 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34485997
Fair regression for health care spending. Zink A, Rose S Biometrics 31860120 Biometrics 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/31860120
Identifying undercompensated groups defined by multiple attributes in risk adjustment. Zink A, Rose S BMJ health & care informatics 34535447 BMJ Health Care Inform 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34535447
Reflection on modern methods: when worlds collide-prediction, machine learning and causal inference. Blakely T, Lynch J, Simons K, Bentley R, Rose S International journal of epidemiology 31298274 Int J Epidemiol 2021 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/31298274
Air pollution exposure disparities across US population and income groups. Jbaily A, Zhou X, Liu J, Lee TH, Kamareddine L, Verguet S, Dominici F Nature 35022594 Nature 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/35022594
Conditional cross-design synthesis estimators for generalizability in Medicaid. Degtiar I, Layton T, Wallace J, Rose S Biometrics 37018228 Biometrics 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37018228
Evaluation of the health impacts of the 1990 Clean Air Act Amendments using causal inference and machine learning. Nethery RC, Mealli F, Sacks JD, Dominici F Journal of the American Statistical Association 33424062 J Am Stat Assoc 2020 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/33424062
Causal inference in high dimensions: A marriage between Bayesian modeling and good frequentist properties. Antonelli J, Papadogeorgou G, Dominici F Biometrics 33349923 Biometrics 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/33349923
Considerations for outcome-dependent biased sampling in health databases. Rose S Statistics in medicine 31489684 Stat Med 2019 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/31489684
Measuring concordance of data sources used for infectious disease research in the USA: a retrospective data analysis. Majumder MS, Cusick M, Rose S BMJ open 36854597 BMJ Open 2023 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/36854597
All Models are Wrong, but Many are Useful: Learning a Variable's Importance by Studying an Entire Class of Prediction Models Simultaneously. Fisher A, Rudin C, Dominici F Journal of machine learning research : JMLR 34335110 J Mach Learn Res 2019 https://www.ncbi.nlm.nih.gov/pubmed/34335110
Uncertainty in lung cancer stage for survival estimation via set-valued classification. Bergquist S, Brooks GA, Landrum MB, Keating NL, Rose S Statistics in medicine 35675972 Stat Med 2022 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/35675972
Discovering Heterogeneous Exposure Effects Using Randomization Inference in Air Pollution Studies. Lee K, Small DS, Dominici F Journal of the American Statistical Association 36311902 J Am Stat Assoc 2021 https://www.ncbi.nlm.nih.gov/pubmed/36311902
Data Source Concordance for Infectious Disease Epidemiology. Majumder M, Cusick MM, Rose S medRxiv : the preprint server for health sciences 35677068 medRxiv 2022 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/35677068
Limitations of P-Values and R-squared for Stepwise Regression Building: A Fairness Demonstration in Health Policy Risk Adjustment. Rose S, McGuire TG The American statistician 31263291 Am Stat 2019 https://www.ncbi.nlm.nih.gov/pubmed/31263291
A causal inference framework for cancer cluster investigations using publicly available data. Nethery RC, Yang Y, Brown AJ, Dominici F Journal of the Royal Statistical Society. Series A, (Statistics in Society) 34262243 J R Stat Soc Ser A Stat Soc 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/34262243
Ethical Machine Learning in Healthcare. Chen IY, Pierson E, Rose S, Joshi S, Ferryman K, Ghassemi M Annual review of biomedical data science 34396058 Annu Rev Biomed Data Sci 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34396058
A generalizable data assembly algorithm for infectious disease outbreaks. Majumder MS, Rose S JAMIA open 34350393 JAMIA Open 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34350393
Improving the Performance of Risk Adjustment Systems: Constrained Regressions, Reinsurance, and Variable Selection. McGuire TG, Zink AL, Rose S American journal of health economics 34869790 Am J Health Econ 2021 Fall https://www.ncbi.nlm.nih.gov/pubmed/34869790
Discussion on "Approval policies for modifications to machine learning-based software as a medical device: A study of biocreep" by Jean Feng, Scott Emerson, and Noah Simon. Rose S Biometrics 33040334 Biometrics 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33040334
Evaluating Federal Policies Using Bayesian Time Series Models: Estimating the Causal Impact of the Hospital Readmissions Reduction Program. Papadogeorgou G, Menchetti F, Choirat C, Wasfy JH, Zigler CM, Mealli F Health services & outcomes research methodology 39866244 Health Serv Outcomes Res Methodol 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/39866244
Evaluating the Health Impact of Large-Scale Public Policy Changes: Classical and Novel Approaches. Basu S, Meghani A, Siddiqi A Annual review of public health 28384086 Annu Rev Public Health 2017 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/28384086
Food Insecurity and Health Care Expenditures in the United States, 2011-2013. Berkowitz SA, Basu S, Meigs JB, Seligman HK Health services research 28608473 Health Serv Res 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/28608473
Preventing false discovery of heterogeneous treatment effect subgroups in randomized trials. Rigdon J, Baiocchi M, Basu S Trials 30012181 Trials 2018 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/30012181
Mother's education and late-life disparities in memory and dementia risk among US military veterans and non-veterans. Vable AM, Eng CW, Mayeda ER, Basu S, Marden JR, Hamad R, Glymour MM Journal of epidemiology and community health 30082424 J Epidemiol Community Health 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30082424
Performance of Matching Methods as Compared With Unmatched Ordinary Least Squares Regression Under Constant Effects. Vable AM, Kiang MV, Glymour MM, Rigdon J, Drabo EF, Basu S American journal of epidemiology 30995301 Am J Epidemiol 2019 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/30995301
Evaluating strategies for control of tuberculosis in prisons and prevention of spillover into communities: An observational and modeling study from Brazil. Mabud TS, de Lourdes Delgado Alves M, Ko AI, Basu S, Walter KS, Cohen T, Mathema B, Colijn C, Lemos E, Croda J, Andrews JR PLoS medicine 30677013 PLoS Med 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30677013
Re-evaluating associations between the Supplemental Nutrition Assistance Program participation and body mass index in the context of unmeasured confounders. Rigdon J, Berkowitz SA, Seligman HK, Basu S Social science & medicine (1982) 28965002 Soc Sci Med 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28965002
Near-Far Matching in R: The nearfar Package. Rigdon J, Baiocchi M, Basu S Journal of statistical software 30386186 J Stat Softw 2018 https://www.ncbi.nlm.nih.gov/pubmed/30386186
Health and Economic Implications of National Treatment Coverage for Cardiovascular Disease in India: Cost-Effectiveness Analysis. Basu S, Bendavid E, Sood N Circulation. Cardiovascular quality and outcomes 26555122 Circ Cardiovasc Qual Outcomes 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26555122
Impact of the North American Free Trade Agreement on high-fructose corn syrup supply in Canada: a natural experiment using synthetic control methods. Barlow P, McKee M, Basu S, Stuckler D CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 28676578 CMAJ 2017 Jul 4 https://www.ncbi.nlm.nih.gov/pubmed/28676578
Dynamic treatment selection and modification for personalised blood pressure therapy using a Markov decision process model: a cost-effectiveness analysis. Choi SE, Brandeau ML, Basu S BMJ open 29146652 BMJ Open 2017 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/29146652
BOUNDS ON THE CONDITIONAL AND AVERAGE TREATMENT EFFECT WITH UNOBSERVED CONFOUNDING FACTORS. Yadlowsky S, Namkoong H, Basu S, Duchi J, Tian L Annals of statistics 38050638 Ann Stat 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/38050638
Supplemental Nutrition Assistance Program (SNAP) Participation and Health Care Expenditures Among Low-Income Adults. Berkowitz SA, Seligman HK, Rigdon J, Meigs JB, Basu S JAMA internal medicine 28973507 JAMA Intern Med 2017 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/28973507
Estimating the long-run relationship between state cigarette taxes and county life expectancy. Baum A, Aguilar-Gomez S, Lightwood J, Bruzelius E, Glantz SA, Basu S Tobacco control 30705247 Tob Control 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/30705247
Huntington's disease in the United States: Variation by demographic and socioeconomic factors. Bruzelius E, Scarpa J, Zhao Y, Basu S, Faghmous JH, Baum A Movement disorders : official journal of the Movement Disorder Society 30868663 Mov Disord 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/30868663
Opioid prescribing patterns among medical providers in the United States, 2003-17: retrospective, observational study. Kiang MV, Humphreys K, Cullen MR, Basu S BMJ (Clinical research ed.) 31996352 BMJ 2020 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/31996352
Personalizing Medical Treatment Decisions: Integrating Meta-analytic Treatment Comparisons with Patient-Specific Risks and Preferences. Weyant C, Brandeau ML, Basu S Medical decision making : an international journal of the Society for Medical Decision Making 31707910 Med Decis Making 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31707910
Basu et al. Respond to "Interdisciplinary Approach for Policy Evaluation". Basu S, Rehkopf DH, Siddiqi A, Glymour MM, Kawachi I American journal of epidemiology 26946397 Am J Epidemiol 2016 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/26946397
Machine Learning Methods for Precision Medicine Research Designed to Reduce Health Disparities: A Structured Tutorial. Basu S, Faghmous JH, Doupe P Ethnicity & disease 32269464 Ethn Dis 2020 https://www.ncbi.nlm.nih.gov/pubmed/32269464
Detecting Anomalies Among Practice Sites Within Multicenter Trials. Berkowitz SA, Rudolph KE, Basu S Circulation. Cardiovascular quality and outcomes 30857413 Circ Cardiovasc Qual Outcomes 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30857413
Association between access to social service resources and cardiometabolic risk factors: a machine learning and multilevel modeling analysis. Berkowitz SA, Basu S, Venkataramani A, Reznor G, Fleegler EW, Atlas SJ BMJ open 30862634 BMJ Open 2019 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/30862634
Food insecurity, healthcare utilization, and high cost: a longitudinal cohort study. Berkowitz SA, Seligman HK, Meigs JB, Basu S The American journal of managed care 30222918 Am J Manag Care 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30222918
Generalizing Intensive Blood Pressure Treatment to Adults With Diabetes Mellitus. Berkowitz SA, Sussman JB, Jonas DE, Basu S Journal of the American College of Cardiology 30189998 J Am Coll Cardiol 2018 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/30189998
Moderation of the Relation of County-Level Cost of Living to Nutrition by the Supplemental Nutrition Assistance Program. Basu S, Wimer C, Seligman H American journal of public health 27631742 Am J Public Health 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27631742
Development and validation of Risk Equations for Complications Of type 2 Diabetes (RECODe) using individual participant data from randomised trials. Basu S, Sussman JB, Berkowitz SA, Hayward RA, Yudkin JS The lancet. Diabetes & endocrinology 28803840 Lancet Diabetes Endocrinol 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28803840
Targeting weight loss interventions to reduce cardiovascular complications of type 2 diabetes: a machine learning-based post-hoc analysis of heterogeneous treatment effects in the Look AHEAD trial. Baum A, Scarpa J, Bruzelius E, Tamler R, Basu S, Faghmous J The lancet. Diabetes & endocrinology 28711469 Lancet Diabetes Endocrinol 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28711469
Long-term effects of neighbourhood deprivation on diabetes risk: quasi-experimental evidence from a refugee dispersal policy in Sweden. White JS, Hamad R, Li X, Basu S, Ohlsson H, Sundquist J, Sundquist K The lancet. Diabetes & endocrinology 27131930 Lancet Diabetes Endocrinol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27131930
Assessment of Changes in the Geographical Distribution of Opioid-Related Mortality Across the United States by Opioid Type, 1999-2016. Kiang MV, Basu S, Chen J, Alexander MJ JAMA network open 30794299 JAMA Netw Open 2019 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/30794299
Machine learning with sparse nutrition data to improve cardiovascular mortality risk prediction in the USA using nationally randomly sampled data. Rigdon J, Basu S BMJ open 31784446 BMJ Open 2019 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/31784446
Matching Microsimulation Risk Factor Correlations to Cross-sectional Data: The Shortest Distance Method. Suen SC, Goldhaber-Fiebert JD, Basu S Medical decision making : an international journal of the Society for Medical Decision Making 29185378 Med Decis Making 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29185378
Health Behaviors, Mental Health, and Health Care Utilization Among Single Mothers After Welfare Reforms in the 1990s. Basu S, Rehkopf DH, Siddiqi A, Glymour MM, Kawachi I American journal of epidemiology 26946395 Am J Epidemiol 2016 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/26946395
Comparative effectiveness and cost-effectiveness of treat-to-target versus benefit-based tailored treatment of type 2 diabetes in low-income and middle-income countries: a modelling analysis. Basu S, Shankar V, Yudkin JS The lancet. Diabetes & endocrinology 27717768 Lancet Diabetes Endocrinol 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27717768
Validation of Risk Equations for Complications of Type 2 Diabetes (RECODe) Using Individual Participant Data From Diverse Longitudinal Cohorts in the U.S. Basu S, Sussman JB, Berkowitz SA, Hayward RA, Bertoni AG, Correa A, Mwasongwe S, Yudkin JS Diabetes care 29269511 Diabetes Care 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29269511
Characteristics Associated With Decreased or Increased Mortality Risk From Glycemic Therapy Among Patients With Type 2 Diabetes and High Cardiovascular Risk: Machine Learning Analysis of the ACCORD Trial. Basu S, Raghavan S, Wexler DJ, Berkowitz SA Diabetes care 29279299 Diabetes Care 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29279299
Decomposition of the US black/white inequality in premature mortality, 2010-2015: an observational study. Kiang MV, Krieger N, Buckee CO, Onnela JP, Chen JT BMJ open 31748287 BMJ Open 2019 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/31748287
Cost Effectiveness of Subsidizing Fruit and Vegetable Purchases Through the Supplemental Nutrition Assistance Program. Choi SE, Seligman H, Basu S American journal of preventive medicine 28153648 Am J Prev Med 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28153648
Anticipated burden and mitigation of carbon-dioxide-induced nutritional deficiencies and related diseases: A simulation modeling study. Weyant C, Brandeau ML, Burke M, Lobell DB, Bendavid E, Basu S PLoS medicine 29969442 PLoS Med 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29969442
Benefit and harm of intensive blood pressure treatment: Derivation and validation of risk models using data from the SPRINT and ACCORD trials. Basu S, Sussman JB, Rigdon J, Steimle L, Denton BT, Hayward RA PLoS medicine 29040268 PLoS Med 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/29040268
Machine Learning for Health Services Researchers. Doupe P, Faghmous J, Basu S Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 31277828 Value Health 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31277828
Personalizing Second-Line Type 2 Diabetes Treatment Selection: Combining Network Meta-analysis, Individualized Risk, and Patient Preferences for Unified Decision Support. Choi SE, Berkowitz SA, Yudkin JS, Naci H, Basu S Medical decision making : an international journal of the Society for Medical Decision Making 30767632 Med Decis Making 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30767632
Black-White Cardiovascular Disease Disparities After Target-Based Versus Personalized Benefit-Based Lipid and Blood Pressure Treatment. Basu S, Sussman JB, Hayward RA MDM policy & practice 30288429 MDM Policy Pract 2017 Jul-Dec https://www.ncbi.nlm.nih.gov/pubmed/30288429
Association of Primary Care Physician Supply With Population Mortality in the United States, 2005-2015. Basu S, Berkowitz SA, Phillips RL, Bitton A, Landon BE, Phillips RS JAMA internal medicine 30776056 JAMA Intern Med 2019 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/30776056
Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk. Yadlowsky S, Hayward RA, Sussman JB, McClelland RL, Min YI, Basu S Annals of internal medicine 29868850 Ann Intern Med 2018 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/29868850
Are There Spillover Effects from the GI Bill? The Mental Health of Wives of Korean War Veterans. Vable AM, Kawachi I, Canning D, Glymour MM, Jimenez MP, Subramanian SV PloS one 27186983 PLoS One 2016 https://www.ncbi.nlm.nih.gov/pubmed/27186983
Alternative Strategies to Achieve Cardiovascular Mortality Goals in China and India: A Microsimulation of Target- Versus Risk-Based Blood Pressure Treatment. Basu S, Yudkin JS, Sussman JB, Millett C, Hayward RA Circulation 26762520 Circulation 2016 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/26762520
The Monthly Cycle of Hypoglycemia: An Observational Claims-based Study of Emergency Room Visits, Hospital Admissions, and Costs in a Commercially Insured Population. Basu S, Berkowitz SA, Seligman H Medical care 28481762 Med Care 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28481762
Detecting Heterogeneous Treatment Effects to Guide Personalized Blood Pressure Treatment: A Modeling Study of Randomized Clinical Trials. Basu S, Sussman JB, Hayward RA Annals of internal medicine 28055048 Ann Intern Med 2017 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/28055048
Illustrating a "consequential" shift in the study of health inequalities: a decomposition of racial differences in the distribution of body mass. Siddiqi A, Shahidi FV, Hildebrand V, Hong A, Basu S Annals of epidemiology 29576050 Ann Epidemiol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29576050
A New Tool for Case Studies in Epidemiology-the Synthetic Control Method. Rehkopf DH, Basu S Epidemiology (Cambridge, Mass.) 29613871 Epidemiology 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29613871
Military Service, Childhood Socio-Economic Status, and Late-Life Lung Function: Korean War Era Military Service Associated with Smaller Disparities. Vable AM, Kiang MV, Basu S, Rudolph KE, Kawachi I, Subramanian SV, Glymour MM Military medicine 29509934 Mil Med 2018 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/29509934
DiracDiffusion: Denoising and Incremental Reconstruction with Assured Data-Consistency. Fabian Z, Tinaz B, Soltanolkotabi M Proceedings of machine learning research 39416230 Proc Mach Learn Res 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/39416230
Adapt and Diffuse: Sample-Adaptive Reconstruction Via Latent Diffusion Models. Fabian Z, Tinaz B, Soltanolkotabi M Proceedings of machine learning research 39318400 Proc Mach Learn Res 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/39318400
Provable Multi-Task Representation Learning by Two-Layer ReLU Neural Networks. Collins L, Hassani H, Soltanolkotabi M, Mokhtari A, Shakkottai S Proceedings of machine learning research 39421278 Proc Mach Learn Res 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/39421278
Gradient Descent Provably Solves Nonlinear Tomographic Reconstruction. Fridovich-Keil S, Valdivia F, Wetzstein G, Recht B, Soltanolkotabi M ArXiv 37873016 ArXiv 2023 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/37873016
Human-in-the-Loop Optimization for Deep Stimulus Encoding in Visual Prostheses. Granley J, Fauvel T, Chalk M, Beyeler M Advances in neural information processing systems 38984104 Adv Neural Inf Process Syst 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/38984104
Efficient Spatial Estimation of Perceptual Thresholds for Retinal Implants via Gaussian Process Regression. Sadeghi R, Beyeler M ArXiv 39990794 ArXiv 2025 Feb 10 https://www.ncbi.nlm.nih.gov/pubmed/39990794
Towards aSmart Bionic Eye: AI-powered artificial vision for the treatment of incurable blindness. Beyeler M, Sanchez-Garcia M Journal of neural engineering 36541463 J Neural Eng 2022 Dec 7 https://www.ncbi.nlm.nih.gov/pubmed/36541463
Aligning Visual Prosthetic Development With Implantee Needs. Nadolskis L, Turkstra LM, Larnyo E, Beyeler M Translational vision science & technology 39570616 Transl Vis Sci Technol 2024 Nov 4 https://www.ncbi.nlm.nih.gov/pubmed/39570616
Aligning visual prosthetic development with implantee needs. Nadolskis LG, Turkstra LM, Larnyo E, Beyeler M medRxiv : the preprint server for health sciences 38559196 medRxiv 2024 Oct 28 https://www.ncbi.nlm.nih.gov/pubmed/38559196
A systematic review of extended reality (XR) for understanding and augmenting vision loss. Kasowski J, Johnson BA, Neydavood R, Akkaraju A, Beyeler M Journal of vision 37140911 J Vis 2023 May 2 https://www.ncbi.nlm.nih.gov/pubmed/37140911
The Relative Importance of Depth Cues and Semantic Edges for Indoor Mobility Using Simulated Prosthetic Vision in Immersive Virtual Reality. Rasla A, Beyeler M Proceedings of the ACM Symposium on Virtual Reality Software and Technology. ACM Symposium on Virtual Reality Software and Technology 40017497 Proc ACM Symp Virtual Real Softw Technol 2022 Nov-Dec https://www.ncbi.nlm.nih.gov/pubmed/40017497
Causal isotonic calibration for heterogeneous treatment effects. van der Laan L, Ulloa-Pérez E, Carone M, Luedtke A Proceedings of machine learning research 37575467 Proc Mach Learn Res 2023 Jul https://www.ncbi.nlm.nih.gov/pubmed/37575467
Improving precision and power in randomized trials for COVID-19 treatments using covariate adjustment, for binary, ordinal, and time-to-event outcomes. Benkeser D, Díaz I, Luedtke A, Segal J, Scharfstein D, Rosenblum M Biometrics 32978962 Biometrics 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/32978962
Correction to: "Optimal Individualized Decision Rules Using Instrumental Variable Methods". Qiu H, Carone M, Sadikova E, Petukhova M, Kessler RC, Luedtke A Journal of the American Statistical Association 35756162 J Am Stat Assoc 2021 https://www.ncbi.nlm.nih.gov/pubmed/35756162
Improved efficiency for cross-arm comparisons via platform designs. Huang TJ, Luedtke A, AMP INVESTIGATOR GROUP Biostatistics (Oxford, England) 35939566 Biostatistics 2023 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/35939566
Improved inference for vaccine-induced immune responses via shape-constrained methods. Laha N, Moodie Z, Huang Y, Luedtke A Electronic journal of statistics 37974631 Electron J Stat 2022 https://www.ncbi.nlm.nih.gov/pubmed/37974631
Inference for treatment-specific survival curves using machine learning. Westling T, Luedtke A, Gilbert PB, Carone M Journal of the American Statistical Association 39184837 J Am Stat Assoc 2024 https://www.ncbi.nlm.nih.gov/pubmed/39184837
Optimal individualized decision rules using instrumental variable methods. Qiu H, Carone M, Sadikova E, Petukhova M, Kessler RC, Luedtke A Journal of the American Statistical Association 33731969 J Am Stat Assoc 2021 https://www.ncbi.nlm.nih.gov/pubmed/33731969
Universal sieve-based strategies for efficient estimation using machine learning tools. Qiu H, Luedtke A, Carone M Bernoulli : official journal of the Bernoulli Society for Mathematical Statistics and Probability 34733110 Bernoulli (Andover) 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34733110
Discussion on "Estimating vaccine efficacy over time after a randomized study is unblinded" by Anastasios A. Tsiatis and Marie Davidian. Janes H, Gao F, Luedtke A Biometrics 34492117 Biometrics 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/34492117
Performance Guarantees for Policy Learning. Luedtke A, Chambaz A Annales de l'I.H.P. Probabilites et statistiques 35321441 Ann I H P Probab Stat 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/35321441
Discussion of and : New Objectives for Policy Learning. Li S, Li X, Luedtke A Journal of the American Statistical Association 36910906 J Am Stat Assoc 2021 https://www.ncbi.nlm.nih.gov/pubmed/36910906
Adversarial Monte Carlo Meta-Learning of Optimal Prediction Procedures. Luedtke A, Chung I, Sofrygin O Journal of machine learning research : JMLR 38476310 J Mach Learn Res 2021 https://www.ncbi.nlm.nih.gov/pubmed/38476310
Rejoinder: Improving precision and power in randomized trials for COVID-19 treatments using covariate adjustment, for binary, ordinal, and time-to-event outcomes. Benkeser D, Díaz I, Luedtke A, Segal J, Scharfstein D, Rosenblum M Biometrics 34050931 Biometrics 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34050931
Re. Selecting Optimal Subgroups for Treatment Using Many Covariates. Penning de Vries BBL, Groenwold RHH, Luedtke A Epidemiology (Cambridge, Mass.) 32282408 Epidemiology 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32282408
Estimating the Efficiency Gain of Covariate-Adjusted Analyses in Future Clinical Trials Using External Data. Li X, Li S, Luedtke A Journal of the Royal Statistical Society. Series B, Statistical methodology 37593690 J R Stat Soc Series B Stat Methodol 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/37593690
Efficient Estimation under Data Fusion. Li S, Luedtke A Biometrika 37982010 Biometrika 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37982010
EFFICIENT ESTIMATION OF THE MAXIMAL ASSOCIATION BETWEEN MULTIPLE PREDICTORS AND A SURVIVAL OUTCOME. Huang TJ, Luedtke A, McKeague IW Annals of statistics 38405375 Ann Stat 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/38405375
Adversarial meta-learning of Gamma-minimax estimators that leverage prior knowledge. Qiu H, Luedtke A Electronic journal of statistics 38463692 Electron J Stat 2023 https://www.ncbi.nlm.nih.gov/pubmed/38463692
Improving Precision and Power in Randomized Trials for COVID-19 Treatments Using Covariate Adjustment, for Binary, Ordinal, and Time-to-Event Outcomes. Benkeser D, Díaz I, Luedtke A, Segal J, Scharfstein D, Rosenblum M medRxiv : the preprint server for health sciences 32577668 medRxiv 2020 Jun 11 https://www.ncbi.nlm.nih.gov/pubmed/32577668
Rejoinder: Optimal individualized decision rules using instrumental variable methods. Qiu H, Carone M, Sadikova E, Petukhova M, Kessler RC, Luedtke A Journal of the American Statistical Association 36092993 J Am Stat Assoc 2021 https://www.ncbi.nlm.nih.gov/pubmed/36092993
A Mixture Model for Estimating SARS-CoV-2 Seroprevalence in Chennai, India. Hitchings MDT, Patel EU, Khan R, Srikrishnan AK, Anderson M, Kumar KS, Wesolowski AP, Iqbal SH, Rodgers MA, Mehta SH, Cloherty G, Cummings DAT, Solomon SS American journal of epidemiology 37084085 Am J Epidemiol 2023 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/37084085
Trip duration drives shift in travel network structure with implications for the predictability of spatial disease spread. Giles JR, Cummings DAT, Grenfell BT, Tatem AJ, Erbach-Schoenberg EZ, Metcalf C, Wesolowski A PLoS computational biology 34375331 PLoS Comput Biol 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34375331
A systematic review of antibody mediated immunity to coronaviruses: antibody kinetics, correlates of protection, and association of antibody responses with severity of disease. Huang AT, Garcia-Carreras B, Hitchings MDT, Yang B, Katzelnick LC, Rattigan SM, Borgert BA, Moreno CA, Solomon BD, Rodriguez-Barraquer I, Lessler J, Salje H, Burke D, Wesolowski A, Cummings DAT medRxiv : the preprint server for health sciences 32511434 medRxiv 2020 Apr 17 https://www.ncbi.nlm.nih.gov/pubmed/32511434
Coexisting attractors in the context of cross-scale population dynamics: measles in London as a case study. Becker AD, Zhou SH, Wesolowski A, Grenfell BT Proceedings. Biological sciences 32315586 Proc Biol Sci 2020 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/32315586
The duration of travel impacts the spatial dynamics of infectious diseases. Giles JR, Zu Erbach-Schoenberg E, Tatem AJ, Gardner L, Bjørnstad ON, Metcalf CJE, Wesolowski A Proceedings of the National Academy of Sciences of the United States of America 32839329 Proc Natl Acad Sci U S A 2020 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/32839329
A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity. Huang AT, Garcia-Carreras B, Hitchings MDT, Yang B, Katzelnick LC, Rattigan SM, Borgert BA, Moreno CA, Solomon BD, Trimmer-Smith L, Etienne V, Rodriguez-Barraquer I, Lessler J, Salje H, Burke DS, Wesolowski A, Cummings DAT Nature communications 32943637 Nat Commun 2020 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/32943637
A systematic review of using population-level human mobility data to understand SARS-CoV-2 transmission. Kostandova N, Schluth C, Arambepola R, Atuhaire F, Bérubé S, Chin T, Cleary E, Cortes-Azuero O, García-Carreras B, Grantz KH, Hitchings MDT, Huang AT, Kishore N, Lai S, Larsen SL, Loisate S, Martinez P, Meredith HR, Purbey R, Ramiadantsoa T, Read J, Rice BL, Rosman L, Ruktanonchai N, Salje H, Schaber KL, Tatem AJ, Wang J, Cummings DAT, Wesolowski A Nature communications 39627231 Nat Commun 2024 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/39627231
Mapping malaria by combining parasite genomic and epidemiologic data. Wesolowski A, Taylor AR, Chang HH, Verity R, Tessema S, Bailey JA, Alex Perkins T, Neafsey DE, Greenhouse B, Buckee CO BMC medicine 30333020 BMC Med 2018 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/30333020
Genetic Evidence of Focal Plasmodium falciparum Transmission in a Pre-elimination Setting in Southern Province, Zambia. Pringle JC, Tessema S, Wesolowski A, Chen A, Murphy M, Carpi G, Shields TM, Hamapumbu H, Searle KM, Kobayashi T, Katowa B, Musonda M, Stevenson JC, Thuma PE, Greenhouse B, Moss WJ, Norris DE The Journal of infectious diseases 30445612 J Infect Dis 2019 Apr 8 https://www.ncbi.nlm.nih.gov/pubmed/30445612
Long-term dynamics of measles in London: Titrating the impact of wars, the 1918 pandemic, and vaccination. Becker AD, Wesolowski A, Bjørnstad ON, Grenfell BT PLoS computational biology 31513578 PLoS Comput Biol 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31513578
Aggregated mobility data could help fight COVID-19. Buckee CO, Balsari S, Chan J, Crosas M, Dominici F, Gasser U, Grad YH, Grenfell B, Halloran ME, Kraemer MUG, Lipsitch M, Metcalf CJE, Meyers LA, Perkins TA, Santillana M, Scarpino SV, Viboud C, Wesolowski A, Schroeder A Science (New York, N.Y.) 32205458 Science 2020 Apr 10 https://www.ncbi.nlm.nih.gov/pubmed/32205458
SARS-CoV-2 Testing in Florida, Illinois, and Maryland: Access and Barriers. Clipman SJ, Wesolowski A, Mehta SH, Agarwal S, Cobey SE, Cummings DAT, Gibson DG, Labrique AB, Kirk GD, Solomon SS medRxiv : the preprint server for health sciences 33398298 medRxiv 2020 Dec 24 https://www.ncbi.nlm.nih.gov/pubmed/33398298
Development and dissemination of infectious disease dynamic transmission models during the COVID-19 pandemic: what can we learn from other pathogens and how can we move forward? Becker AD, Grantz KH, Hegde ST, Bérubé S, Cummings DAT, Wesolowski A The Lancet. Digital health 33735068 Lancet Digit Health 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33735068
Reconstructing unseen transmission events to infer dengue dynamics from viral sequences. Salje H, Wesolowski A, Brown TS, Kiang MV, Berry IM, Lefrancq N, Fernandez S, Jarman RG, Ruchusatsawat K, Iamsirithaworn S, Vandepitte WP, Suntarattiwong P, Read JM, Klungthong C, Thaisomboonsuk B, Engø-Monsen K, Buckee C, Cauchemez S, Cummings DAT Nature communications 33753725 Nat Commun 2021 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/33753725
The Challenge of Achieving Immunity Through Multiple-Dose Vaccines in Madagascar. Jones FK, Mensah K, Heraud JM, Randriatsarafara FM, Metcalf CJE, Wesolowski A American journal of epidemiology 34023892 Am J Epidemiol 2021 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/34023892
Epidemiology of Plasmodium falciparum Infections in a Semi-Arid Rural African Setting: Evidence from Reactive Case Detection in Northwestern Kenya. Meredith HR, Wesolowski A, Menya D, Esimit D, Lokoel G, Kipkoech J, Freedman B, Lokemer S, Maragia J, Ambani G, Taylor SM, Prudhomme-O'Meara W, Obala AA The American journal of tropical medicine and hygiene 34339387 Am J Trop Med Hyg 2021 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/34339387
The use of mobile phone data to inform analysis of COVID-19 pandemic epidemiology. Grantz KH, Meredith HR, Cummings DAT, Metcalf CJE, Grenfell BT, Giles JR, Mehta S, Solomon S, Labrique A, Kishore N, Buckee CO, Wesolowski A Nature communications 32999287 Nat Commun 2020 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/32999287
High Plasmodium falciparum genetic diversity and temporal stability despite control efforts in high transmission settings along the international border between Zambia and the Democratic Republic of the Congo. Pringle JC, Wesolowski A, Berube S, Kobayashi T, Gebhardt ME, Mulenga M, Chaponda M, Bobanga T, Juliano JJ, Meshnick S, Moss WJ, Carpi G, Norris DE Malaria journal 31801548 Malar J 2019 Dec 4 https://www.ncbi.nlm.nih.gov/pubmed/31801548
Mapping imported malaria in Bangladesh using parasite genetic and human mobility data. Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A, Uddin D, Zaman SI, Hossain MA, Faiz MA, Ghose A, Sayeed AA, Rahman MR, Islam A, Karim MJ, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Drury E, Gonçalves S, Kekre M, Dhorda M, Vongpromek R, Miotto O, Engø-Monsen K, Kwiatkowski D, Maude RJ, Buckee C eLife 30938289 Elife 2019 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/30938289
Existing human mobility data sources poorly predicted the spatial spread of SARS-CoV-2 in Madagascar. Ramiadantsoa T, Metcalf CJE, Raherinandrasana AH, Randrianarisoa S, Rice BL, Wesolowski A, Randriatsarafara FM, Rasambainarivo F Epidemics 34915300 Epidemics 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/34915300
Long-term effects of increased adoption of artemisinin combination therapies in Burkina Faso. Zupko RJ, Nguyen TD, Somé AF, Tran TN, Gerardin J, Dudas P, Giang DDH, Tran KT, Wesolowski A, Ouédraogo JB, Boni MF PLOS global public health 36962300 PLOS Glob Public Health 2022 https://www.ncbi.nlm.nih.gov/pubmed/36962300
Using parasite genetic and human mobility data to infer local and cross-border malaria connectivity in Southern Africa. Tessema S, Wesolowski A, Chen A, Murphy M, Wilheim J, Mupiri AR, Ruktanonchai NW, Alegana VA, Tatem AJ, Tambo M, Didier B, Cohen JM, Bennett A, Sturrock HJ, Gosling R, Hsiang MS, Smith DL, Mumbengegwi DR, Smith JL, Greenhouse B eLife 30938286 Elife 2019 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/30938286
Seasonal gaps in measles vaccination coverage in Madagascar. Mensah K, Heraud JM, Takahashi S, Winter AK, Metcalf CJE, Wesolowski A Vaccine 30940486 Vaccine 2019 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/30940486
Mapping the travel patterns of people with malaria in Bangladesh. Sinha I, Sayeed AA, Uddin D, Wesolowski A, Zaman SI, Faiz MA, Ghose A, Rahman MR, Islam A, Karim MJ, Saha A, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Chang HH, Miotto O, Kwiatkowski D, Dondorp AM, Day NPJ, Hossain MA, Buckee C, Maude RJ BMC medicine 32127002 BMC Med 2020 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/32127002
Using models to shape measles control and elimination strategies in low- and middle-income countries: A review of recent applications. Cutts FT, Dansereau E, Ferrari MJ, Hanson M, McCarthy KA, Metcalf CJE, Takahashi S, Tatem AJ, Thakkar N, Truelove S, Utazi E, Wesolowski A, Winter AK Vaccine 31787412 Vaccine 2020 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/31787412
Infectious disease in an era of global change. Baker RE, Mahmud AS, Miller IF, Rajeev M, Rasambainarivo F, Rice BL, Takahashi S, Tatem AJ, Wagner CE, Wang LF, Wesolowski A, Metcalf CJE Nature reviews. Microbiology 34646006 Nat Rev Microbiol 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/34646006
Holiday gatherings, mobility and SARS-CoV-2 transmission: results from 10 US states following Thanksgiving. Mehta SH, Clipman SJ, Wesolowski A, Solomon SS Scientific reports 34462499 Sci Rep 2021 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/34462499
Who is missed in a community-based survey: Assessment and implications of biases due to incomplete sampling frame in a community-based serosurvey, Choma and Ndola Districts, Zambia, 2022. Kostandova N, Mutembo S, Prosperi C, Mwansa FD, Nakazwe C, Namukoko H, Nachinga B, Chongwe G, Chilumba I, Matakala KH, Musukwa G, Hamahuwa M, Mufwambi W, Matoba J, Situtu K, Mutale I, Kong AC, Simulundu E, Ndubani P, Hasan AZ, Truelove SA, Winter AK, Carcelen AC, Lau B, Moss WJ, Wesolowski A PLOS global public health 38683820 PLOS Glob Public Health 2024 https://www.ncbi.nlm.nih.gov/pubmed/38683820
Characterizing mobility patterns and malaria risk factors in semi-nomadic populations of Northern Kenya. Meredith HR, Wesolowski A, Okoth D, Maraga L, Ambani G, Chepkwony T, Abel L, Kipkoech J, Lokoel G, Esimit D, Lokemer S, Maragia J, Prudhomme O'Meara W, Obala AA PLOS global public health 38478562 PLOS Glob Public Health 2024 https://www.ncbi.nlm.nih.gov/pubmed/38478562
Exploring how space, time, and sampling impact our ability to measure genetic structure across Plasmodium falciparum populations. Arambepola R, Bérubé S, Freedman B, Taylor SM, Prudhomme O'Meara W, Obala AA, Wesolowski A Frontiers in epidemiology 38516334 Front Epidemiol 2023 https://www.ncbi.nlm.nih.gov/pubmed/38516334
Effect of non-pharmaceutical interventions to contain COVID-19 in China. Lai S, Ruktanonchai NW, Zhou L, Prosper O, Luo W, Floyd JR, Wesolowski A, Santillana M, Zhang C, Du X, Yu H, Tatem AJ Nature 32365354 Nature 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32365354
National-scale simulation of human movement in a spatially coupled individual-based model of malaria in Burkina Faso. Zupko RJ, Nguyen TD, Wesolowski A, Gerardin J, Boni MF Scientific reports 36609584 Sci Rep 2023 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/36609584
Using geospatial models to map zero-dose children: factors associated with zero-dose vaccination status before and after a mass measles and rubella vaccination campaign in Southern province, Zambia. Arambepola R, Yang Y, Hutchinson K, Mwansa FD, Doherty JA, Bwalya F, Ndubani P, Musukwa G, Moss WJ, Wesolowski A, Mutembo S BMJ global health 34969682 BMJ Glob Health 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34969682
Challenges in evaluating risks and policy options around endemic establishment or elimination of novel pathogens. Metcalf CJE, Andriamandimby SF, Baker RE, Glennon EE, Hampson K, Hollingsworth TD, Klepac P, Wesolowski A Epidemics 34823222 Epidemics 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34823222
Prioritizing COVID-19 vaccination efforts and dose allocation within Madagascar. Rasambainarivo F, Ramiadantsoa T, Raherinandrasana A, Randrianarisoa S, Rice BL, Evans MV, Roche B, Randriatsarafara FM, Wesolowski A, Metcalf JC BMC public health 35413894 BMC Public Health 2022 Apr 12 https://www.ncbi.nlm.nih.gov/pubmed/35413894
Rapid real-time tracking of non-pharmaceutical interventions and their association with SARS-CoV-2 positivity: The COVID-19 Pandemic Pulse Study. Clipman SJ, Wesolowski AP, Gibson DG, Agarwal S, Lambrou AS, Kirk GD, Labrique AB, Mehta SH, Solomon SS medRxiv : the preprint server for health sciences 32766598 medRxiv 2020 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/32766598
Rapid Real-time Tracking of Nonpharmaceutical Interventions and Their Association With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Positivity: The Coronavirus Disease 2019 (COVID-19) Pandemic Pulse Study. Clipman SJ, Wesolowski AP, Gibson DG, Agarwal S, Lambrou AS, Kirk GD, Labrique AB, Mehta SH, Solomon SS Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 32877921 Clin Infect Dis 2021 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/32877921
Existing human mobility data sources poorly predicted the spatial spread of SARS-CoV-2 in Madagascar. Ramiadantsoa T, Metcalf CJE, Raherinandrasana AH, Randrianarisoa S, Rice BL, Wesolowski A, Randriatsarafara FM, Rasambainarivo F medRxiv : the preprint server for health sciences 34373863 medRxiv 2021 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/34373863
Improvements in Severe Acute Respiratory Syndrome Coronavirus 2 Testing Cascade in the United States: Data From Serial Cross-sectional Assessments. Clipman SJ, Wesolowski A, Mehta SH, Cobey S, Cummings DAT, Solomon SS Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 34374758 Clin Infect Dis 2022 May 3 https://www.ncbi.nlm.nih.gov/pubmed/34374758
Characterizing human mobility patterns in rural settings of sub-Saharan Africa. Meredith HR, Giles JR, Perez-Saez J, Mande T, Rinaldo A, Mutembo S, Kabalo EN, Makungo K, Buckee CO, Tatem AJ, Metcalf CJE, Wesolowski A eLife 34533456 Elife 2021 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/34533456
Towards better targeting: lessons from a posthoneymoon measles outbreak in Madagascar, 2018-2019. Raherindrasana A, Metcalf CJ, Heraud JM, Cauchemez S, Winter A, Wesolowski A, Razafindratsimandresy R, Randriamampionona L, Rafalimanantsoa SA, Masembe Y, Ndiaye C, Rakotonirina J BMJ global health 33082133 BMJ Glob Health 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/33082133
Seroprevalence of pertussis in Madagascar and implications for vaccination. Razafimahatratra SL, Wesolowski A, Rafetrarivony L, Heraud JM, Jones FK, Cauchemez S, Razafindratsimandresy R, Raharinantoanina SJ, Harimanana A, Collard JM, Metcalf CJE Epidemiology and infection 33190665 Epidemiol Infect 2020 Nov 16 https://www.ncbi.nlm.nih.gov/pubmed/33190665
Changes in mobility patterns during the COVID-19 pandemic in Zambia: Implications for the effectiveness of NPIs in Sub-Saharan Africa. Loisate S, Mutembo S, Arambepola R, Makungo K, Kabalo EN, Sinyange NB, Kapata N, Liwewe M, Silumezi A, Chongwe G, Kostandova N, Truelove S, Wesolowski A PLOS global public health 37906535 PLOS Glob Public Health 2023 https://www.ncbi.nlm.nih.gov/pubmed/37906535
Impact of disruptions to routine vaccination programs, quantifying burden of measles, and mapping targeted supplementary immunization activities. Kostandova N, Loisate S, Winter A, Moss WJ, Giles JR, Metcalf CJE, Mutembo S, Wesolowski A Epidemics 36343498 Epidemics 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36343498
Fine scale human mobility changes within 26 US cities in 2020 in response to the COVID-19 pandemic were associated with distance and income. Arambepola R, Schaber KL, Schluth C, Huang AT, Labrique AB, Mehta SH, Solomon SS, Cummings DAT, Wesolowski A PLOS global public health 37478056 PLOS Glob Public Health 2023 https://www.ncbi.nlm.nih.gov/pubmed/37478056
Characterizing mobility patterns and malaria risk factors in semi-nomadic populations of Northern Kenya. Meredith HR, Wesolowski A, Okoth D, Maraga L, Ambani G, Chepkwony T, Abel L, Kipkoech J, Lokoel G, Esimit D, Lokemer S, Maragia J, O'Meara WP, Obala AA medRxiv : the preprint server for health sciences 38106223 medRxiv 2023 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/38106223
Geography versus sociodemographics as predictors of changes in daily mobility across the USA during the COVID-19 pandemic: a two-stage regression analysis across 26 metropolitan areas. Schaber K, Arambepola R, Schluth C, Labrique AB, Mehta SH, Solomon SS, Cummings DAT, Wesolowski A BMJ open 38986558 BMJ Open 2024 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/38986558
Clinician Conceptualization of the Benefits of Treatments for Individual Patients. Morgan DJ, Pineles L, Owczarzak J, Magder L, Scherer L, Brown JP, Pfeiffer C, Terndrup C, Leykum L, Feldstein D, Foy A, Stevens D, Koch C, Masnick M, Weisenberg S, Korenstein D JAMA network open 34287630 JAMA Netw Open 2021 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/34287630
Clinician Attitudes and Beliefs Associated with More Aggressive Diagnostic Testing. Korenstein D, Scherer LD, Foy A, Pineles L, Lydecker AD, Owczarzak J, Magder L, Brown JP, Pfeiffer CD, Terndrup C, Leykum L, Stevens D, Feldstein DA, Weisenberg SA, Baghdadi JD, Morgan DJ The American journal of medicine 35307357 Am J Med 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35307357
Game-based learning to improve diagnostic accuracy: a pilot randomized-controlled trial. Morgan DJ, Scherer L, Pineles L, Baghdadi J, Magder L, Thom K, Koch C, Wilkins N, LeGrand M, Stevens D, Walker R, Shirrell B, Harris AD, Korenstein D Diagnosis (Berlin, Germany) 38284830 Diagnosis (Berl) 2024 May 1 https://www.ncbi.nlm.nih.gov/pubmed/38284830
Reply to Fakih and Advani. Trautner BW, Morgan DJ Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 33821997 Clin Infect Dis 2021 May 4 https://www.ncbi.nlm.nih.gov/pubmed/33821997
Exploration of Primary Care Clinician Attitudes and Cognitive Characteristics Associated With Prescribing Antibiotics for Asymptomatic Bacteriuria. Baghdadi JD, Korenstein D, Pineles L, Scherer LD, Lydecker AD, Magder L, Stevens DN, Morgan DJ JAMA network open 35622364 JAMA Netw Open 2022 May 2 https://www.ncbi.nlm.nih.gov/pubmed/35622364
Medical overuse of therapies and diagnostics in rheumatology. Khawaja MN, Alhassan E, Bilal J, Jatwani S, Mehta B, Bhalla V, Morgan DJ, Siaton BC, Hochberg MC Clinical rheumatology 33569709 Clin Rheumatol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33569709
Accuracy of Practitioner Estimates of Probability of Diagnosis Before and After Testing. Morgan DJ, Pineles L, Owczarzak J, Magder L, Scherer L, Brown JP, Pfeiffer C, Terndrup C, Leykum L, Feldstein D, Foy A, Stevens D, Koch C, Masnick M, Weisenberg S, Korenstein D JAMA internal medicine 33818595 JAMA Intern Med 2021 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/33818595
Clinician Testing and Treatment Thresholds for Management of Urinary Tract Infection. Harris A, Pineles L, Baghdadiv JD, Magder L, Dhaliwal G, Korenstein D, Harris AD, Morgan DJ Open forum infectious diseases 37720701 Open Forum Infect Dis 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37720701
Not Thinking Clearly? Play a Game, Seriously! Mohan D, Schell J, Angus DC JAMA 27825014 JAMA 2016 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/27825014
Testing a videogame intervention to recalibrate physician heuristics in trauma triage: study protocol for a randomized controlled trial. Mohan D, Rosengart MR, Fischhoff B, Angus DC, Farris C, Yealy DM, Wallace DJ, Barnato AE BMC emergency medicine 27835981 BMC Emerg Med 2016 Nov 11 https://www.ncbi.nlm.nih.gov/pubmed/27835981
Selection bias, interventions and outcomes for survivors of cardiac arrest. Wallace DJ, Coppler P, Callaway C, Rittenberger JC, Dezfulian C, Mohan D, Toma C, Elmer J Heart (British Cardiac Society) 29463613 Heart 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29463613
Using Virtual Reality Simulation Environments to Assess Competence for Emergency Medicine Learners. McGrath JL, Taekman JM, Dev P, Danforth DR, Mohan D, Kman N, Crichlow A, Bond WF Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 28888070 Acad Emerg Med 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/28888070
Nudges in the Care of the Critically Ill. Wallace DJ, Drake C, Mohan D Critical care medicine 31305299 Crit Care Med 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31305299
Association of Practitioner Interfacility Triage Performance With Outcomes for Severely Injured Patients With Fee-for-Service Medicare Insurance. Mohan D, Wallace DJ, Kerti SJ, Angus DC, Rosengart MR, Barnato AE, Yealy DM, Fischhoff B, Chang CC, Kahn JM JAMA surgery 31642889 JAMA Surg 2019 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/31642889
Efficacy of educational video game versus traditional educational apps at improving physician decision making in trauma triage: randomized controlled trial. Mohan D, Farris C, Fischhoff B, Rosengart MR, Angus DC, Yealy DM, Wallace DJ, Barnato AE BMJ (Clinical research ed.) 29233854 BMJ 2017 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/29233854
Using incentives to recruit physicians into behavioral trials: lessons learned from four studies. Mohan D, Rosengart MR, Fischhoff B, Angus DC, Wallace DJ, Farris C, Yealy DM, Barnato AE BMC research notes 29282154 BMC Res Notes 2017 Dec 28 https://www.ncbi.nlm.nih.gov/pubmed/29282154
Constructing within and between hospital physician social networks for modeling physician research participation. Bobak CA, Mohan D, Murphy MA, Barnato AE, O'Malley AJ BMC medical research methodology 37898745 BMC Med Res Methodol 2023 Oct 28 https://www.ncbi.nlm.nih.gov/pubmed/37898745
Outcomes after a Digital Behavior Change Intervention to Improve Trauma Triage: An Analysis of Medicare Claims. Mohan D, Chang CC, Fischhoff B, Rosengart MR, Angus DC, Yealy DM, Barnato AE The Journal of surgical research 34464890 J Surg Res 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34464890
Serious games may improve physician heuristics in trauma triage. Mohan D, Fischhoff B, Angus DC, Rosengart MR, Wallace DJ, Yealy DM, Farris C, Chang CH, Kerti S, Barnato AE Proceedings of the National Academy of Sciences of the United States of America 30150397 Proc Natl Acad Sci U S A 2018 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/30150397
Referral Regions for Time-Sensitive Acute Care Conditions in the United States. Wallace DJ, Mohan D, Angus DC, Driessen JR, Seymour CM, Yealy DM, Roberts MM, Kurland KS, Kahn JM Annals of emergency medicine 29606286 Ann Emerg Med 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29606286
Development of a theory-based video-game intervention to increase advance care planning conversations by healthcare providers. Mohan D, MacMartin MA, Chelen JSC, Maezes CB, Barnato AE Implementation science communications 34645515 Implement Sci Commun 2021 Oct 13 https://www.ncbi.nlm.nih.gov/pubmed/34645515
Using a Video Game Intervention to Increase Hospitalists' Advance Care Planning Conversations with Older Adults: a Stepped Wedge Randomized Clinical Trial. Mohan D, O'Malley AJ, Chelen J, MacMartin M, Murphy M, Rudolph M, Engel JA, Barnato AE Journal of general internal medicine 37429972 J Gen Intern Med 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37429972
Using a theory-based, customized video game as an educational tool to improve physicians' trauma triage decisions: study protocol for a randomized cluster trial. Mohan D, Angus DC, Chang CH, Elmer J, Fischhoff B, Rak KJ, Barnes JL, Peitzman AB, White DB Trials 38365758 Trials 2024 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/38365758
Videogame intervention to increase advance care planning conversations by hospitalists with older adults: study protocol for a stepped-wedge clinical trial. Mohan D, O'Malley AJ, Chelen J, MacMartin M, Murphy M, Rudolph M, Barnato A BMJ open 33753443 BMJ Open 2021 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/33753443
Does Preexisting Practice Modify How Video Games Recalibrate Physician Heuristics in Trauma Triage? Kulkarni SS, Barnato AE, Rosengart MR, Fischhoff B, Angus DC, Yealy DM, Wallace DJ, Mohan D The Journal of surgical research 31071605 J Surg Res 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31071605
Inner Deliberations of Surgeons Treating Critically-ill Emergency General Surgery Patients: A Qualitative Analysis. Kulkarni SS, Briggs A, Sacks OA, Rosengart MR, White DB, Barnato AE, Peitzman AB, Mohan D Annals of surgery 31714316 Ann Surg 2021 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/31714316
Defining the representativeness heuristic in trauma triage: A retrospective observational cohort study. Kulkarni SS, Dewitt B, Fischhoff B, Rosengart MR, Angus DC, Saul M, Yealy DM, Mohan D PloS one 30735553 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/30735553
Testing a Novel Deliberate Practice Intervention to Improve Diagnostic Reasoning in Trauma Triage: A Pilot Randomized Clinical Trial. Mohan D, Elmer J, Arnold RM, Forsythe RM, Fischhoff B, Rak K, Barnes JL, White DB JAMA network open 37195666 JAMA Netw Open 2023 May 1 https://www.ncbi.nlm.nih.gov/pubmed/37195666
Testing the feasibility, acceptability, and preliminary effect of a novel deliberate practice intervention to reduce diagnostic error in trauma triage: a study protocol for a randomized pilot trial. Mohan D, Elmer J, Arnold RM, Forsythe RM, Fischhoff B, Rak K, Barnes JL, White DB Pilot and feasibility studies 36510328 Pilot Feasibility Stud 2022 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/36510328
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Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection. Sukumar N, Tan S, Aldridge BB, Russell DG PLoS pathogens 25233380 PLoS Pathog 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25233380
Morphological profiling of tubercle bacilli identifies drug pathways of action. Smith TC 2nd, Pullen KM, Olson MC, McNellis ME, Richardson I, Hu S, Larkins-Ford J, Wang X, Freundlich JS, Ando DM, Aldridge BB Proceedings of the National Academy of Sciences of the United States of America 32680963 Proc Natl Acad Sci U S A 2020 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/32680963
Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis. Cokol M, Kuru N, Bicak E, Larkins-Ford J, Aldridge BB Science advances 29026882 Sci Adv 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/29026882
A Parallel Adder Coordinates Mycobacterial Cell-Cycle Progression and Cell-Size Homeostasis in the Context of Asymmetric Growth and Organization. Logsdon MM, Ho PY, Papavinasasundaram K, Richardson K, Cokol M, Sassetti CM, Amir A, Aldridge BB Current biology : CB 29107550 Curr Biol 2017 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/29107550
Rv0004 is a new essential member of the mycobacterial DNA replication machinery. Mann KM, Huang DL, Hooppaw AJ, Logsdon MM, Richardson K, Lee HJ, Kimmey JM, Aldridge BB, Stallings CL PLoS genetics 29176877 PLoS Genet 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/29176877
Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling. Li M, Patel HV, Cognetta AB 3rd, Smith TC 2nd, Mallick I, Cavalier JF, Previti ML, Canaan S, Aldridge BB, Cravatt BF, Seeliger JC Cell chemical biology 34599873 Cell Chem Biol 2022 May 19 https://www.ncbi.nlm.nih.gov/pubmed/34599873
Stress-Induced Reorganization of the Mycobacterial Membrane Domain. Hayashi JM, Richardson K, Melzer ES, Sandler SJ, Aldridge BB, Siegrist MS, Morita YS mBio 29362232 mBio 2018 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/29362232
Temporal and intrinsic factors of rifampicin tolerance in mycobacteria. Richardson K, Bennion OT, Tan S, Hoang AN, Cokol M, Aldridge BB Proceedings of the National Academy of Sciences of the United States of America 27357669 Proc Natl Acad Sci U S A 2016 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/27357669
Prediction of ultra-high-order antibiotic combinations based on pairwise interactions. Katzir I, Cokol M, Aldridge BB, Alon U PLoS computational biology 30699106 PLoS Comput Biol 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30699106
Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis. Ma S, Jaipalli S, Larkins-Ford J, Lohmiller J, Aldridge BB, Sherman DR, Chandrasekaran S mBio 31719182 mBio 2019 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/31719182
Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action. Boot M, Commandeur S, Subudhi AK, Bahira M, Smith TC 2nd, Abdallah AM, van Gemert M, Lelièvre J, Ballell L, Aldridge BB, Pain A, Speer A, Bitter W Antimicrobial agents and chemotherapy 29661879 Antimicrob Agents Chemother 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29661879
Stable Regulation of Cell Cycle Events in Mycobacteria: Insights From Inherently Heterogeneous Bacterial Populations. Logsdon MM, Aldridge BB Frontiers in microbiology 29619019 Front Microbiol 2018 https://www.ncbi.nlm.nih.gov/pubmed/29619019
Influence of Stress and Antibiotic Resistance on Cell-Length Distribution in Mycobacterium tuberculosis Clinical Isolates. Vijay S, Vinh DN, Hai HT, Ha VTN, Dung VTM, Dinh TD, Nhung HN, Tram TTB, Aldridge BB, Hanh NT, Thu DDA, Phu NH, Thwaites GE, Thuong NTT Frontiers in microbiology 29209302 Front Microbiol 2017 https://www.ncbi.nlm.nih.gov/pubmed/29209302
Foundation models for generalizable electrocardiogram interpretation: comparison of supervised and self-supervised electrocardiogram foundation models. Nolin-Lapalme A, Sowa A, Delfrate J, Tastet O, Corbin D, Kulbay M, Ozdemir D, Noël MJ, Marois-Blanchet FC, Harvey F, Sharma S, Ansari M, Chiu IM, Dsouza V, Friedman SF, Chassé M, Potter BJ, Afilalo J, Elias PA, Jabbour G, Bahani M, Dubé MP, Boyle PM, Chatterjee NA, Barrios J, Tison GH, Ouyang D, Maddah M, Khurshid S, Cadrin-Tourigny J, Tadros R, Hussin J, Avram R medRxiv : the preprint server for health sciences 40093248 medRxiv 2025 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/40093248
Substrate stiffness modulates cardiac fibroblast activation, senescence, and proinflammatory secretory phenotype. Felisbino MB, Rubino M, Travers JG, Schuetze KB, Lemieux ME, Anseth KS, Aguado BA, McKinsey TA American journal of physiology. Heart and circulatory physiology 37889253 Am J Physiol Heart Circ Physiol 2024 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/37889253
Secreted Cytokines From Inflammatory Macrophages Modulate Sex Differences in Valvular Interstitial Cells on Hydrogel Biomaterials. Félix Vélez NE, Tu K, Guo P, Reeves RR, Aguado BA Journal of biomedical materials research. Part A 39995146 J Biomed Mater Res A 2025 Mar https://www.ncbi.nlm.nih.gov/pubmed/39995146
Y chromosome-linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues. Gorashi RM, Baddour T, Chittle SJ, Félix Vélez NE, Wenning MA, Anseth KS, Mestroni L, Peña B, Guo P, Aguado BA Science advances 40073144 Sci Adv 2025 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/40073144
Y chromosome linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues. Gorashi RM, Baddour T, Chittle SJ, Vélez NEF, Wenning MA, Anseth KS, Mestroni L, Peña B, Guo P, Aguado BA bioRxiv : the preprint server for biology 38798394 bioRxiv 2024 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/38798394
Reactivation of an Embryonic Cardiac Neural Crest Transcriptional Subcircuit During Zebrafish Heart Regeneration. Dhillon-Richardson RM, Haugan AK, Lyons LW, McKenna JK, Bronner ME, Martik ML bioRxiv : the preprint server for biology 39868190 bioRxiv 2025 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/39868190
Daily social comparisons among women in midlife with elevated risk for cardiovascular disease: A within-person test of the identification/contrast model. Baga K, Salvatore GM, Bercovitz I, Mogle JA, Arigo D Applied psychology. Health and well-being 38785210 Appl Psychol Health Well Being 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/38785210
A Visual, In-Expensive, and Wireless Capillary Rheometer for Characterizing Wholly-Cellular Bioinks. Du J, Lee S, Sinha S, Solberg FS, Ho DLL, Sampson JP, Wang Q, Tam T, Skylar-Scott MA Small (Weinheim an der Bergstrasse, Germany) 38085139 Small 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38085139
Rapid model-guided design of organ-scale synthetic vasculature for biomanufacturing. Sexton ZA, Hudson AR, Herrmann JE, Shiwarski DJ, Pham J, Szafron JM, Wu SM, Skylar-Scott M, Feinberg AW, Marsden A ArXiv 37645046 ArXiv 2023 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/37645046
A Low-Cost, Open-Source 3D Printer for Multimaterial and High-Throughput Direct Ink Writing of Soft and Living Materials. Weiss JD, Mermin-Bunnell A, Solberg FS, Tam T, Rosalia L, Sharir A, Rütsche D, Sinha S, Choi PS, Shibata M, Palagani Y, Nilkant R, Paulvannan K, Ma M, Skylar-Scott MA Advanced materials (Deerfield Beach, Fla.) 39748617 Adv Mater 2025 Mar https://www.ncbi.nlm.nih.gov/pubmed/39748617
Multiscale elasticity mapping of biological samples in 3D at optical resolution. Regan K, LeBourdais R, Banerji R, Zhang S, Muhvich J, Zheng S, Nia HT Acta biomaterialia 38160857 Acta Biomater 2024 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/38160857
Emergence of nanoscale viscoelasticity from single cancer cells to established tumors. Hadzipasic M, Zhang S, Huang Z, Passaro R, Sten MS, Shankar GM, Nia HT Biomaterials 38169188 Biomaterials 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38169188
The peritumor microenvironment: physics and immunity. Zhang S, Regan K, Najera J, Grinstaff MW, Datta M, Nia HT Trends in cancer 37156677 Trends Cancer 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37156677
Crystal ribcage: a platform for probing real-time lung function at cellular resolution. Banerji R, Grifno GN, Shi L, Smolen D, LeBourdais R, Muhvich J, Eberman C, Hiller BE, Lee J, Regan K, Zheng S, Zhang S, Jiang J, Raslan AA, Breda JC, Pihl R, Traber K, Mazzilli S, Ligresti G, Mizgerd JP, Suki B, Nia HT Nature methods 37710017 Nat Methods 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37710017
B cells in the pneumococcus-infected lung are heterogeneous and require CD4(+) T cell help including CD40L to become resident memory B cells. Etesami NS, Barker KA, Shenoy AT, De Ana CL, Arafa EI, Grifno GN, Matschulat AM, Vannini ME, Pihl RMF, Breen MP, Soucy AM, Goltry WN, Ha CT, Betsuyaku H, Browning JL, Varelas X, Traber KE, Jones MR, Quinton LJ, Maglione PJ, Nia HT, Belkina AC, Mizgerd JP Frontiers in immunology 38715601 Front Immunol 2024 https://www.ncbi.nlm.nih.gov/pubmed/38715601
Mapping the strain-stiffening behavior of the lung and lung cancer at microscale resolution using the crystal ribcage. LeBourdais R, Grifno GN, Banerji R, Regan K, Suki B, Nia HT Frontiers in network physiology 39050550 Front Netw Physiol 2024 https://www.ncbi.nlm.nih.gov/pubmed/39050550
Alteration of mechanical stresses in the murine brain by age and hemorrhagic stroke. Zheng S, Banerji R, LeBourdais R, Zhang S, DuBois E, O'Shea T, Nia HT PNAS nexus 38659974 PNAS Nexus 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38659974
Intravital measurements of solid stresses in tumours reveal length-scale and microenvironmentally dependent force transmission. Zhang S, Grifno G, Passaro R, Regan K, Zheng S, Hadzipasic M, Banerji R, O'Connor L, Chu V, Kim SY, Yang J, Shi L, Karrobi K, Roblyer D, Grinstaff MW, Nia HT Nature biomedical engineering 37640900 Nat Biomed Eng 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37640900
A CAR enhancer increases the activity and persistence of CAR T cells. Rakhshandehroo T, Mantri SR, Moravej H, Louis BBV, Salehi Farid A, Munaretto L, Regan K, Khan RMM, Wolff A, Farkash Z, Cong M, Kuhnast A, Nili A, Lee UJ, Allen HH, Berland L, Simkova E, Uslu SC, Tavakolpour S, Rowley JE, Codet E, Shahbazian H, Baral J, Pyrdol J, Jacobson CA, Nadeem O, Nia HT, Wucherpfennig KW, Rashidian M Nature biotechnology 39079964 Nat Biotechnol 2024 Jul 30 https://www.ncbi.nlm.nih.gov/pubmed/39079964
Dreaming of electrical waves: Generative modeling of cardiac excitation waves using diffusion models. Baranwal T, Lebert J, Christoph J APL machine learning 39364376 APL Mach Learn 2024 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/39364376
Reconstruction of three-dimensional scroll waves in excitable media from two-dimensional observations using deep neural networks. Lebert J, Mittal M, Christoph J Physical review. E 36797900 Phys Rev E 2023 Jan https://www.ncbi.nlm.nih.gov/pubmed/36797900
Paralysis by analysis: Overcoming cardiac contraction with computer vision. Christoph J, Ripplinger CM Proceedings of the National Academy of Sciences of the United States of America 37792520 Proc Natl Acad Sci U S A 2023 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/37792520
Author Correction: O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology. Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR Nature chemical biology 38413747 Nat Chem Biol 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38413747
Update on Disease-Specific Biomarkers in Transthyretin Cardiac Amyloidosis. Hood CJ, Hendren NS, Pedretti R, Roth LR, Saelices L, Grodin JL Current heart failure reports 35930129 Curr Heart Fail Rep 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/35930129
Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2. Tayeb-Fligelman E, Cheng X, Tai C, Bowler JT, Griner S, Sawaya MR, Seidler PM, Jiang YX, Lu J, Rosenberg GM, Salwinski L, Abskharon R, Zee CT, Hou K, Li Y, Boyer DR, Murray KA, Falcon G, Anderson DH, Cascio D, Saelices L, Damoiseaux R, Guo F, Eisenberg DS bioRxiv : the preprint server for biology 33688654 bioRxiv 2021 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/33688654
O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology. Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR Nature chemical biology 38347213 Nat Chem Biol 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38347213
Detection of Circulating Transthyretin Amyloid Aggregates in Plasma: A Novel Biomarker for Transthyretin Amyloidosis. Pedretti R, Wang L, Hanna M, Benson MD, Grodin JL, Tang WHW, Masri A, Saelices L Circulation 38768274 Circulation 2024 May 21 https://www.ncbi.nlm.nih.gov/pubmed/38768274
The inhibition of cellular toxicity of amyloid-β by dissociated transthyretin. Cao Q, Anderson DH, Liang WY, Chou J, Saelices L The Journal of biological chemistry 32769117 J Biol Chem 2020 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/32769117
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS Nature communications 37185252 Nat Commun 2023 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/37185252
Amyloid fibril polymorphism in the heart of an ATTR amyloidosis patient with polyneuropathy attributed to the V122Δ variant. Ahmed Y, Nguyen BA, Afrin S, Singh V, Evers B, Singh P, Pedretti R, Wang L, Bassett P, Del Carmen Fernandez-Ramirez M, Pekala M, Kluve-Beckerman B, Saelices L bioRxiv : the preprint server for biology 38766262 bioRxiv 2024 May 10 https://www.ncbi.nlm.nih.gov/pubmed/38766262
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis. Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski P, Chhapra F, Saelices L bioRxiv : the preprint server for biology 38496656 bioRxiv 2024 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/38496656
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pękała M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L Nature communications 38233397 Nat Commun 2024 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/38233397
Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores. Cao Q, Boyer DR, Sawaya MR, Abskharon R, Saelices L, Nguyen BA, Lu J, Murray KA, Kandeel F, Eisenberg DS Nature structural & molecular biology 34518699 Nat Struct Mol Biol 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34518699
Disease-associated patterns of acetylation stabilize tau fibril formation. Li L, Nguyen B, Mullapudi V, Saelices L, Joachimiak LA bioRxiv : the preprint server for biology 36711822 bioRxiv 2023 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/36711822
O-GlcNAc modification forces the formation of an α-Synuclein amyloid-strain with notably diminished seeding activity and pathology. Balana AT, Mahul-Mellier AL, Nguyen BA, Horvath M, Javed A, Hard ER, Jasiqi Y, Singh P, Afrin S, Pedretti R, Singh V, Lee VM, Luk KC, Saelices L, Lashuel HA, Pratt MR bioRxiv : the preprint server for biology 36945566 bioRxiv 2023 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/36945566
ATTRv-V30M amyloid fibrils from heart and nerves exhibit structural homogeneity. Nguyen BA, Afrin S, Yakubovska A, Singh V, Pedretti R, Bassett P, Pekala M, Alicea JV, Kunach P, Wang L, Lemoff A, Kluve-Beckerman B, Saelices L Structure (London, England : 1993) 39423808 Structure 2024 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/39423808
Structure-Based Probe Reveals the Presence of Large Transthyretin Aggregates in Plasma of ATTR Amyloidosis Patients. Pedretti R, Wang L, Yakubovska A, Zhang QS, Nguyen B, Grodin JL, Masri A, Saelices L JACC. Basic to translational science 39444930 JACC Basic Transl Sci 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/39444930
Biomarkers in Subclinical Transthyretin Cardiac Amyloidosis. Gulati JS, Pedretti R, Hendren N, Kozlitina J, Saelices L, Roth LR, Grodin JL Current heart failure reports 39945945 Curr Heart Fail Rep 2025 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/39945945
Conformational inhibitors of protein aggregation. Fernández Ramírez MDC, Afrin S, Saelices L Current opinion in structural biology 37717490 Curr Opin Struct Biol 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37717490
Multi-organ structural homogeneity of amyloid fibrils in ATTRv-T60A amyloidosis patients, revealed by Cryo-EM. Fernandez-Ramirez MDC, Nguyen BA, Singh V, Afrin S, Evers B, Basset P, Wang L, Pękała M, Ahmed Y, Singh P, Canepa J, Wosztyl A, Li Y, Saelices L bioRxiv : the preprint server for biology 38798519 bioRxiv 2024 May 14 https://www.ncbi.nlm.nih.gov/pubmed/38798519
Disease-associated patterns of acetylation stabilize tau fibril formation. Li L, Nguyen BA, Mullapudi V, Li Y, Saelices L, Joachimiak LA Structure (London, England : 1993) 37348495 Structure 2023 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/37348495
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis. Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski PM, Chhapra F, Saelices L Communications biology 39068302 Commun Biol 2024 Jul 27 https://www.ncbi.nlm.nih.gov/pubmed/39068302
ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity. Nguyen BA, Afrin S, Yakubovska A, Singh V, Alicea JV, Kunach P, Singh P, Pekala M, Ahmed Y, Fernandez-Ramirez MDC, Hernandez LOC, Pedretti R, Bassett P, Wang L, Lemoff A, Villalon L, Kluve-Beckerman B, Saelices L bioRxiv : the preprint server for biology 38798361 bioRxiv 2024 May 14 https://www.ncbi.nlm.nih.gov/pubmed/38798361
Detection of ATTR aggregates in the plasma of polyneuropathic patients with ATTR-V30M amyloidosis. Pedretti R, Wang L, Grodin JL, Masri A, Kelly J, Saelices L Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 39283068 Amyloid 2024 Dec https://www.ncbi.nlm.nih.gov/pubmed/39283068
Heterogeneity and Functional Analysis of Cardiac Fibroblasts in Heart Development. Deng Y, He Y, Xu J, He H, Li G bioRxiv : the preprint server for biology 37577541 bioRxiv 2023 Jul 31 https://www.ncbi.nlm.nih.gov/pubmed/37577541
Cardiac Fibroblasts regulate myocardium and coronary vasculature development via the collagen signaling pathway. Deng Y, He Y, Xu J, He H, Zhang M, Li G bioRxiv : the preprint server for biology 39314489 bioRxiv 2025 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/39314489
Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency. Feng W, Schriever H, Jiang S, Bais A, Wu H, Kostka D, Li G Communications biology 35488063 Commun Biol 2022 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/35488063
Modeling Human Heart Development and Congenital Defects Using Organoids: How Close Are We? Jiang S, Feng W, Chang C, Li G Journal of cardiovascular development and disease 35621836 J Cardiovasc Dev Dis 2022 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/35621836
Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages. Feng W, Bais A, He H, Rios C, Jiang S, Xu J, Chang C, Kostka D, Li G Nature communications 36575170 Nat Commun 2022 Dec 27 https://www.ncbi.nlm.nih.gov/pubmed/36575170
Keratin 19 (Krt19) is a novel marker gene for epicardial cells. Xu J, Deng Y, Li G Frontiers in genetics 38831775 Front Genet 2024 https://www.ncbi.nlm.nih.gov/pubmed/38831775
Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias. Haghighi K, Gardner G, Vafiadaki E, Kumar M, Green LC, Ma J, Crocker JS, Koch S, Arvanitis DA, Bidwell P, Rubinstein J, van de Leur R, Doevendans PA, Akar FG, Tranter M, Wang HS, Sadayappan S, DeMazumder D, Sanoudou D, Hajjar RJ, Stillitano F, Kranias EG Journal of personalized medicine 34204946 J Pers Med 2021 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/34204946
Contemporary Applications of Machine Learning for Device Therapy in Heart Failure. Gautam N, Ghanta SN, Clausen A, Saluja P, Sivakumar K, Dhar G, Chang Q, DeMazumder D, Rabbat MG, Greene SJ, Fudim M, Al'Aref SJ JACC. Heart failure 36049812 JACC Heart Fail 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/36049812
Artificial Intelligence, Wearables and Remote Monitoring for Heart Failure: Current and Future Applications. Gautam N, Ghanta SN, Mueller J, Mansour M, Chen Z, Puente C, Ha YM, Tarun T, Dhar G, Sivakumar K, Zhang Y, Halimeh AA, Nakarmi U, Al-Kindi S, DeMazumder D, Al'Aref SJ Diagnostics (Basel, Switzerland) 36552971 Diagnostics (Basel) 2022 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/36552971
Reply: Pathophysiology of Takotsubo Syndrome Explored in the Cardiac Electrophysiology Laboratory. DeMazumder D, Thirumal R, Wittstein IS, Calkins H JACC. Clinical electrophysiology 35589185 JACC Clin Electrophysiol 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35589185
Cardiac sympathetic denervation prevents sudden cardiac arrest and improves cardiac function by enhancing mitochondrial-antioxidant capacity. Dey S, Joshi P, O'Rourke B, Estes S, DeMazumder D bioRxiv : the preprint server for biology 36778270 bioRxiv 2023 Oct 28 https://www.ncbi.nlm.nih.gov/pubmed/36778270
Neurocardiac Changes Preceding and During the Onset of Takotsubo Cardiomyopathy in the Cardiac Electrophysiology Laboratory. Thirumal R, Wittstein IS, Calkins H, DeMazumder D JACC. Clinical electrophysiology 35210091 JACC Clin Electrophysiol 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/35210091
Ryanodine receptor 2 inhibition reduces dispersion of cardiac repolarization, improves contractile function, and prevents sudden arrhythmic death in failing hearts. Joshi P, Estes S, DeMazumder D, Knollmann BC, Dey S eLife 38078905 Elife 2023 Dec 11 https://www.ncbi.nlm.nih.gov/pubmed/38078905
Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease. Uddin MDM, Nguyen NQH, Yu B, Brody JA, Pampana A, Nakao T, Fornage M, Bressler J, Sotoodehnia N, Weinstock JS, Honigberg MC, Nachun D, Bhattacharya R, Griffin GK, Chander V, Gibbs RA, Rotter JI, Liu C, Baccarelli AA, Chasman DI, Whitsel EA, Kiel DP, Murabito JM, Boerwinkle E, Ebert BL, Jaiswal S, Floyd JS, Bick AG, Ballantyne CM, Psaty BM, Natarajan P, Conneely KN Nature communications 36097025 Nat Commun 2022 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/36097025
Clonal hematopoiesis associated with epigenetic aging and clinical outcomes. Nachun D, Lu AT, Bick AG, Natarajan P, Weinstock J, Szeto MD, Kathiresan S, Abecasis G, Taylor KD, Guo X, Tracy R, Durda P, Liu Y, Johnson C, Rich SS, Van Den Berg D, Laurie C, Blackwell T, Papanicolaou GJ, Correa A, Raffield LM, Johnson AD, Murabito J, Manson JE, Desai P, Kooperberg C, Assimes TL, Levy D, Rotter JI, Reiner AP, Whitsel EA, Wilson JG, Horvath S, Jaiswal S, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium Aging cell 34050697 Aging Cell 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34050697
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis. Kim PG, Niroula A, Shkolnik V, McConkey M, Lin AE, Słabicki M, Kemp JP, Bick A, Gibson CJ, Griffin G, Sekar A, Brooks DJ, Wong WJ, Cohen DN, Uddin MM, Shin WJ, Pirruccello J, Tsai JM, Agrawal M, Kiel DP, Bouxsein ML, Richards JB, Evans DM, Wein MN, Charles JF, Jaiswal S, Natarajan P, Ebert BL The Journal of experimental medicine 34698806 J Exp Med 2021 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/34698806
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk. Yu Z, Fidler TP, Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T, Niroula A, Heimlich JB, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, Levy D, Vasan RS, Aguet F, Ardlie KG, Taylor KD, Rich SS, Rotter JI, Libby P, Jaiswal S, Ebert BL, Bick AG, Tall AR, Natarajan P The Journal of clinical investigation 37498674 J Clin Invest 2023 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/37498674
Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease. Jaiswal S, Libby P Nature reviews. Cardiology 31406340 Nat Rev Cardiol 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/31406340
ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Beauchamp EM, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Gallì A, Castellano CA, McConkey M, Tarun A, Wong W, Schenone M, Stanclift C, Tanenbaum B, Malolepsza E, Nilsson B, Bick AG, Weinstock JS, Miller M, Niroula A, Dunford A, Taylor-Weiner A, Wood T, Barbera A, Anand S, Psaty BM, Desai P, Cho MH, Johnson AD, Loos R, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, MacArthur DG, Lek M, Exome Aggregation Consortium, Neuberg DS, Lage K, Carr SA, Hellstrom-Lindberg E, Malcovati L, Papaemmanuil E, Stewart C, Getz G, Bradley RK, Jaiswal S, Ebert BL Blood cancer discovery 34568833 Blood Cancer Discov 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34568833
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential. Nakao T, Bick AG, Taub MA, Zekavat SM, Uddin MM, Niroula A, Carty CL, Lane J, Honigberg MC, Weinstock JS, Pampana A, Gibson CJ, Griffin GK, Clarke SL, Bhattacharya R, Assimes TL, Emery LS, Stilp AM, Wong Q, Broome J, Laurie CA, Khan AT, Smith AV, Blackwell TW, Codd V, Nelson CP, Yoneda ZT, Peralta JM, Bowden DW, Irvin MR, Boorgula M, Zhao W, Yanek LR, Wiggins KL, Hixson JE, Gu CC, Peloso GM, Roden DM, Reupena MS, Hwu CM, DeMeo DL, North KE, Kelly S, Musani SK, Bis JC, Lloyd-Jones DM, Johnsen JM, Preuss M, Tracy RP, Peyser PA, Qiao D, Desai P, Curran JE, Freedman BI, Tiwari HK, Chavan S, Smith JA, Smith NL, Kelly TN, Hidalgo B, Cupples LA, Weeks DE, Hawley NL, Minster RL, Samoan Obesity, Lifestyle and Genetic Adaptations Study (OLaGA) Group, Deka R, Naseri TT, de las Fuentes L, Raffield LM, Morrison AC, Vries PS, Ballantyne CM, Kenny EE, Rich SS, Whitsel EA, Cho MH, Shoemaker MB, Pace BS, Blangero J, Palmer ND, Mitchell BD, Shuldiner AR, Barnes KC, Redline S, Kardia SLR, Abecasis GR, Becker LC, Heckbert SR, He J, Post W, Arnett DK, Vasan RS, Darbar D, Weiss ST, McGarvey ST, de Andrade M, Chen YI, Kaplan RC, Meyers DA, Custer BS, Correa A, Psaty BM, Fornage M, Manson JE, Boerwinkle E, Konkle BA, Loos RJF, Rotter JI, Silverman EK, Kooperberg C, Danesh J, Samani NJ, Jaiswal S, Libby P, Ellinor PT, Pankratz N, Ebert BL, Reiner AP, Mathias RA, Do R, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Natarajan P Science advances 35385311 Sci Adv 2022 Apr 8 https://www.ncbi.nlm.nih.gov/pubmed/35385311
TET2-mutant clonal hematopoiesis and risk of gout. Agrawal M, Niroula A, Cunin P, McConkey M, Shkolnik V, Kim PG, Wong WJ, Weeks LD, Lin AE, Miller PG, Gibson CJ, Sekar A, Schaefer IM, Neuberg D, Stone RM, Bick AG, Uddin MM, Griffin GK, Jaiswal S, Natarajan P, Nigrovic PA, Rao DA, Ebert BL Blood 35714308 Blood 2022 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/35714308
Prediction of risk for myeloid malignancy in clonal hematopoiesis. Weeks LD, Niroula A, Neuberg D, Wong W, Lindsley RC, Luskin M, Berliner N, Stone RM, DeAngelo DJ, Soiffer R, Uddin MM, Griffin G, Vlasschaert C, Gibson CJ, Jaiswal S, Bick AG, Malcovati L, Natarajan P, Ebert BL NEJM evidence 37483562 NEJM Evid 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37483562
Clonal haematopoiesis and atherosclerotic cardiovascular disease. Ahmad H, Jaiswal S Nature reviews. Cardiology 37169832 Nat Rev Cardiol 2023 Jul https://www.ncbi.nlm.nih.gov/pubmed/37169832
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes. Weinstock JS, Laurie CA, Broome JG, Taylor KD, Guo X, Shuldiner AR, O'Connell JR, Lewis JP, Boerwinkle E, Barnes KC, Chami N, Kenny EE, Loos RJF, Fornage M, Redline S, Cade BE, Gilliland FD, Chen Z, Gauderman WJ, Kumar R, Grammer L, Schleimer RP, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Qiao D, Weiss ST, Lasky-Su J, DeMeo DL, Palmer ND, Freedman BI, Bowden DW, Cho MH, Vasan RS, Johnson AD, Yanek LR, Becker LC, Kardia S, He J, Kaplan R, Heckbert SR, Smith NL, Wiggins KL, Arnett DK, Irvin MR, Tiwari H, Correa A, Raffield LM, Gao Y, de Andrade M, Rotter JI, Rich SS, Manichaikul AW, Konkle BA, Johnsen JM, Wheeler MM, Custer BS, Duggirala R, Curran JE, Blangero J, Gui H, Xiao S, Williams LK, Meyers DA, Li X, Ortega V, McGarvey S, Gu CC, Chen YI, Lee WJ, Shoemaker MB, Darbar D, Roden D, Albert C, Kooperberg C, Desai P, Blackwell TW, Abecasis GR, Smith AV, Kang HM, Mathias R, Natarajan P, Jaiswal S, Reiner AP, Bick AG, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium Science advances 37126548 Sci Adv 2023 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/37126548
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis. Weinstock JS, Gopakumar J, Burugula BB, Uddin MM, Jahn N, Belk JA, Bouzid H, Daniel B, Miao Z, Ly N, Mack TM, Luna SE, Prothro KP, Mitchell SR, Laurie CA, Broome JG, Taylor KD, Guo X, Sinner MF, von Falkenhausen AS, Kääb S, Shuldiner AR, O'Connell JR, Lewis JP, Boerwinkle E, Barnes KC, Chami N, Kenny EE, Loos RJF, Fornage M, Hou L, Lloyd-Jones DM, Redline S, Cade BE, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Qiao D, Palmer ND, Freedman BI, Bowden DW, Cho MH, DeMeo DL, Vasan RS, Yanek LR, Becker LC, Kardia SLR, Peyser PA, He J, Rienstra M, Van der Harst P, Kaplan R, Heckbert SR, Smith NL, Wiggins KL, Arnett DK, Irvin MR, Tiwari H, Cutler MJ, Knight S, Muhlestein JB, Correa A, Raffield LM, Gao Y, de Andrade M, Rotter JI, Rich SS, Tracy RP, Konkle BA, Johnsen JM, Wheeler MM, Smith JG, Melander O, Nilsson PM, Custer BS, Duggirala R, Curran JE, Blangero J, McGarvey S, Williams LK, Xiao S, Yang M, Gu CC, Chen YI, Lee WJ, Marcus GM, Kane JP, Pullinger CR, Shoemaker MB, Darbar D, Roden DM, Albert C, Kooperberg C, Zhou Y, Manson JE, Desai P, Johnson AD, Mathias RA, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Blackwell TW, Abecasis GR, Smith AV, Kang HM, Satpathy AT, Natarajan P, Kitzman JO, Whitsel EA, Reiner AP, Bick AG, Jaiswal S Nature 37046083 Nature 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/37046083
Clonal haematopoiesis and risk of chronic liver disease. Wong WJ, Emdin C, Bick AG, Zekavat SM, Niroula A, Pirruccello JP, Dichtel L, Griffin G, Uddin MM, Gibson CJ, Kovalcik V, Lin AE, McConkey ME, Vromman A, Sellar RS, Kim PG, Agrawal M, Weinstock J, Long MT, Yu B, Banerjee R, Nicholls RC, Dennis A, Kelly M, Loh PR, McCarroll S, Boerwinkle E, Vasan RS, Jaiswal S, Johnson AD, Chung RT, Corey K, Levy D, Ballantyne C, NHLBI TOPMed Hematology Working Group, Ebert BL, Natarajan P Nature 37046084 Nature 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/37046084
Clonal Hematopoiesis and Its Impact on Human Health. Ahmad H, Jahn N, Jaiswal S Annual review of medicine 36450282 Annu Rev Med 2023 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/36450282
Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias. Schuermans A, Vlasschaert C, Nauffal V, Cho SMJ, Uddin MM, Nakao T, Niroula A, Klarqvist MDR, Weeks LD, Lin AE, Saadatagah S, Lannery K, Wong M, Hornsby W, Lubitz SA, Ballantyne C, Jaiswal S, Libby P, Ebert BL, Bick AG, Ellinor PT, Natarajan P, Honigberg MC European heart journal 37952204 Eur Heart J 2024 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/37952204
Human Coronary Plaque T Cells Are Clonal and Cross-React to Virus and Self. Chowdhury RR, D'Addabbo J, Huang X, Veizades S, Sasagawa K, Louis DM, Cheng P, Sokol J, Jensen A, Tso A, Shankar V, Wendel BS, Bakerman I, Liang G, Koyano T, Fong R, Nau AN, Ahmad H, Gopakumar J, Wirka R, Lee AS, Boyd J, Woo YJ, Quertermous T, Gulati GS, Jaiswal S, Chien YH, Chan CKF, Davis MM, Nguyen PK Circulation research 35430876 Circ Res 2022 May 13 https://www.ncbi.nlm.nih.gov/pubmed/35430876
Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Sabino EC, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, NHLBI Trans-Omics for Precision Medicine Consortium, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan P Nature 33057201 Nature 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/33057201
Insights into clonal hematopoiesis and its relation to cancer risk. Mitchell SR, Gopakumar J, Jaiswal S Current opinion in genetics & development 33422951 Curr Opin Genet Dev 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33422951
Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease. Gumuser ED, Schuermans A, Cho SMJ, Sporn ZA, Uddin MM, Paruchuri K, Nakao T, Yu Z, Haidermota S, Hornsby W, Weeks LD, Niroula A, Jaiswal S, Libby P, Ebert BL, Bick AG, Natarajan P, Honigberg MC Journal of the American College of Cardiology 37197843 J Am Coll Cardiol 2023 May 23 https://www.ncbi.nlm.nih.gov/pubmed/37197843
Clonal hematopoiesis and nonhematologic disorders. Jaiswal S Blood 32736379 Blood 2020 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/32736379
Author Correction: Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease. Jaiswal S, Libby P Nature reviews. Cardiology 32616879 Nat Rev Cardiol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32616879
Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood. Schuermans A, Nakao T, Ruan Y, Koyama S, Yu Z, Uddin MM, Haidermota S, Hornsby W, Lewandowski AJ, Bick AG, Niroula A, Jaiswal S, Ebert BL, Natarajan P, Honigberg MC Journal of the American Heart Association 37345823 J Am Heart Assoc 2023 Jul 4 https://www.ncbi.nlm.nih.gov/pubmed/37345823
Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics. Uddin MM, Zhou Y, Bick AG, Burugula BB, Jaiswal S, Desai P, Honigberg MC, Love SA, Barac A, Hayden KM, Manson JE, Whitsel EA, Kooperberg C, Natarajan P, Reiner AP, Kitzman JO Immunity & ageing : I & A 35610705 Immun Ageing 2022 May 24 https://www.ncbi.nlm.nih.gov/pubmed/35610705
Clonal Hematopoiesis Is Associated With Higher Risk of Stroke. Bhattacharya R, Zekavat SM, Haessler J, Fornage M, Raffield L, Uddin MM, Bick AG, Niroula A, Yu B, Gibson C, Griffin G, Morrison AC, Psaty BM, Longstreth WT, Bis JC, Rich SS, Rotter JI, Tracy RP, Correa A, Seshadri S, Johnson A, Collins JM, Hayden KM, Madsen TE, Ballantyne CM, Jaiswal S, Ebert BL, Kooperberg C, Manson JE, Whitsel EA, NHLBI Trans-Omics for Precision Medicine Program, Natarajan P, Reiner AP Stroke 34743536 Stroke 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/34743536
Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia. Duncavage EJ, Bagg A, Hasserjian RP, DiNardo CD, Godley LA, Iacobucci I, Jaiswal S, Malcovati L, Vannucchi AM, Patel KP, Arber DA, Arcila ME, Bejar R, Berliner N, Borowitz MJ, Branford S, Brown AL, Cargo CA, Döhner H, Falini B, Garcia-Manero G, Haferlach T, Hellström-Lindberg E, Kim AS, Klco JM, Komrokji R, Lee-Cheun Loh M, Loghavi S, Mullighan CG, Ogawa S, Orazi A, Papaemmanuil E, Reiter A, Ross DM, Savona M, Shimamura A, Skoda RC, Solé F, Stone RM, Tefferi A, Walter MJ, Wu D, Ebert BL, Cazzola M Blood 36130297 Blood 2022 Nov 24 https://www.ncbi.nlm.nih.gov/pubmed/36130297
Association of clonal hematopoiesis with chronic obstructive pulmonary disease. Miller PG, Qiao D, Rojas-Quintero J, Honigberg MC, Sperling AS, Gibson CJ, Bick AG, Niroula A, McConkey ME, Sandoval B, Miller BC, Shi W, Viswanathan K, Leventhal M, Werner L, Moll M, Cade BE, Barr RG, Correa A, Cupples LA, Gharib SA, Jain D, Gogarten SM, Lange LA, London SJ, Manichaikul A, O'Connor GT, Oelsner EC, Redline S, Rich SS, Rotter JI, Ramachandran V, Yu B, Sholl L, Neuberg D, Jaiswal S, Levy BD, Owen CA, Natarajan P, Silverman EK, van Galen P, Tesfaigzi Y, Cho MH, Ebert BL, COPDGene Study Investigators, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium Blood 34855941 Blood 2022 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/34855941
Clonal hematopoiesis is associated with protection from Alzheimer's disease. Bouzid H, Belk JA, Jan M, Qi Y, Sarnowski C, Wirth S, Ma L, Chrostek MR, Ahmad H, Nachun D, Yao W, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Beiser A, Bick AG, Bis JC, Fornage M, Longstreth WT Jr, Lopez OL, Natarajan P, Psaty BM, Satizabal CL, Weinstock J, Larson EB, Crane PK, Keene CD, Seshadri S, Satpathy AT, Montine TJ, Jaiswal S Nature medicine 37322115 Nat Med 2023 Jul https://www.ncbi.nlm.nih.gov/pubmed/37322115
Epigenetic and proteomic signatures associate with clonal hematopoiesis expansion rate. Mack TM, Raddatz MA, Pershad Y, Nachun DC, Taylor KD, Guo X, Shuldiner AR, O'Connell JR, Kenny EE, Loos RJF, Redline S, Cade BE, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Cho MH, DeMeo DL, Levy D, Johnson AD, Mathias RA, Yanek LR, Heckbert SR, Smith NL, Wiggins KL, Raffield LM, Carson AP, Rotter JI, Rich SS, Manichaikul AW, Gu CC, Chen YI, Lee WJ, Shoemaker MB, Roden DM, Kooperberg C, Auer PL, Desai P, Blackwell TW, Smith AV, Reiner AP, Jaiswal S, Weinstock JS, Bick AG Nature aging 38834882 Nat Aging 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38834882
Human Plasma Proteomic Profile of Clonal Hematopoiesis. Yu Z, Vromman A, Nguyen NQH, Schuermans A, Rentz T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir U, Fang S, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Ramachandran VS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg CL, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, NHLBI Trans-Omics for Precision Medicine, Libby P, Gupta RM, Natarajan P bioRxiv : the preprint server for biology 39554199 bioRxiv 2024 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/39554199
InUtero Gene Therapy: Progress and Challenges. Bose SK, Menon P, Peranteau WH Trends in molecular medicine 34176774 Trends Mol Med 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34176774
Foetal genome editing. Bose SK, Kennedy K, Peranteau WH Current opinion in obstetrics & gynecology 36924409 Curr Opin Obstet Gynecol 2023 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/36924409
In utero pulse injection of isotopic amino acids quantifies protein turnover rates during murine fetal development. Baeza J, Coons BE, Lin Z, Riley J, Mendoza M, Peranteau WH, Garcia BA bioRxiv : the preprint server for biology 37293076 bioRxiv 2023 May 21 https://www.ncbi.nlm.nih.gov/pubmed/37293076
Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice. Riley JS, Luks VL, Berkowitz CL, Dumitru AM, Kus NJ, Dave A, Menon P, De Paepe ME, Jain R, Li L, Dugoff L, Teefey CP, Alameh MG, Zoltick PW, Peranteau WH The Journal of clinical investigation 38950310 J Clin Invest 2024 May 9 https://www.ncbi.nlm.nih.gov/pubmed/38950310
Molecular and Cellular In Utero Therapy. Berkowitz CL, Luks VL, Puc M, Peranteau WH Clinics in perinatology 36328600 Clin Perinatol 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36328600
Fetal allotransplant recipients are resistant to graft-versus-host disease. Riley JS, McClain LE, Stratigis JD, Coons BE, Bose SK, Dave A, White BM, Li H, Loukogeorgakis SP, Fachin CG, Dias AIBS, Flake AW, Peranteau WH Experimental hematology 36535408 Exp Hematol 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/36535408
Improved specificity and efficacy of base-editing therapies with hybrid guide RNAs. Whittaker MN, Brooks DL, Quigley A, Jindal I, Said H, Qu P, Wang JZ, Ahrens-Nicklas RC, Musunuru K, Alameh MG, Peranteau WH, Wang X bioRxiv : the preprint server for biology 38712058 bioRxiv 2024 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/38712058
Immune modulation permits tolerance and engraftment in a murine model of late-gestation transplantation. Riley JS, Berkowitz CL, Luks VL, Dave A, Cyril-Olutayo MC, Pogoriler J, Flake AW, Abdulmalik O, Peranteau WH Blood advances 38941538 Blood Adv 2024 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/38941538
In utero hematopoietic cell transplantation leads to sustained engraftment in a mouse model of Fanconi anemia. Dave A, Liu S, Riley JS, Bose S, Luks V, Berkowitz C, Menon P, Jung S, Li H, Kurre P, Peranteau WH Blood advances 37906519 Blood Adv 2024 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/37906519
Fetal and Maternal Safety Considerations for In Utero Therapy Clinical Trials: iFeTiS Consensus Statement. Sagar R, Almeida-Porada G, Blakemore K, Chan JKY, Choolani M, Götherström C, Jaulent A, MacKenzie TC, Mattar C, Porada CD, Peranteau WH, Schneider H, Shaw SW, Waddington SN, Westgren M, David AL Molecular therapy : the journal of the American Society of Gene Therapy 33069884 Mol Ther 2020 Nov 4 https://www.ncbi.nlm.nih.gov/pubmed/33069884
The Future of In Utero Gene Therapy. Peranteau WH, Flake AW Molecular diagnosis & therapy 32020561 Mol Diagn Ther 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32020561
In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease. Bose SK, White BM, Kashyap MV, Dave A, De Bie FR, Li H, Singh K, Menon P, Wang T, Teerdhala S, Swaminathan V, Hartman HA, Jayachandran S, Chandrasekaran P, Musunuru K, Jain R, Frank DB, Zoltick P, Peranteau WH Nature communications 34257302 Nat Commun 2021 Jul 13 https://www.ncbi.nlm.nih.gov/pubmed/34257302
Prenatal Gene Therapy for Metabolic Disorders. Coons B, Peranteau WH Clinical obstetrics and gynecology 34652302 Clin Obstet Gynecol 2021 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/34652302
Comment on: Premature delivery in the domestic sow in response to in utero delivery of AAV9 to fetal piglets. Dave A, Berkowitz CL, Luks VL, White BM, Palanki R, Carpenter MD, Riley JS, Bose SK, Li H, Li L, Menon PV, Teerdhala S, Ebrahimi M, Zoltick PW, Peranteau WH Gene therapy 36918654 Gene Ther 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36918654
Fetal gene therapy. Waddington SN, Peranteau WH, Rahim AA, Boyle AK, Kurian MA, Gissen P, Chan JKY, David AL Journal of inherited metabolic disease 37470194 J Inherit Metab Dis 2024 Jan https://www.ncbi.nlm.nih.gov/pubmed/37470194
The emerging role of extracellular vesicles in bronchopulmonary dysplasia. Ransom MA, Blatt AM, Pua HH, Sucre JMS American journal of physiology. Lung cellular and molecular physiology 38469633 Am J Physiol Lung Cell Mol Physiol 2024 May 1 https://www.ncbi.nlm.nih.gov/pubmed/38469633
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Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency. Wessels MW, Cnossen MH, van Dijk TB, Gillemans N, Schmidt KLJ, van Lom K, Vinjamur DS, Coyne S, Kurita R, Nakamura Y, de Man SA, Pfundt R, Azmani Z, Brouwer RWW, Bauer DE, van den Hout MCGN, van IJcken WFJ, Philipsen S Blood advances 33938942 Blood Adv 2021 May 11 https://www.ncbi.nlm.nih.gov/pubmed/33938942
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Technical considerations for the use of CRISPR/Cas9 in hematology research. Gundry MC, Dever DP, Yudovich D, Bauer DE, Haas S, Wilkinson AC, Singbrant S Experimental hematology 28757433 Exp Hematol 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28757433
DrugThatGene: integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens. Canver MC, Bauer DE, Maeda T, Pinello L Bioinformatics (Oxford, England) 30395160 Bioinformatics 2019 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/30395160
Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation. Rao S, Yao Y, Bauer DE Genome medicine 33691767 Genome Med 2021 Mar 10 https://www.ncbi.nlm.nih.gov/pubmed/33691767
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data. Hsu JY, Fulco CP, Cole MA, Canver MC, Pellin D, Sher F, Farouni R, Clement K, Guo JA, Biasco L, Orkin SH, Engreitz JM, Lander ES, Joung JK, Bauer DE, Pinello L Nature methods 30504875 Nat Methods 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30504875
AmpUMI: design and analysis of unique molecular identifiers for deep amplicon sequencing. Clement K, Farouni R, Bauer DE, Pinello L Bioinformatics (Oxford, England) 29949956 Bioinformatics 2018 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/29949956
14q32 and let-7 microRNAs regulate transcriptional networks in fetal and adult human erythroblasts. Lessard S, Beaudoin M, Orkin SH, Bauer DE, Lettre G Human molecular genetics 29432581 Hum Mol Genet 2018 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/29432581
Highly efficient therapeutic gene editing of human hematopoietic stem cells. Wu Y, Zeng J, Roscoe BP, Liu P, Yao Q, Lazzarotto CR, Clement K, Cole MA, Luk K, Baricordi C, Shen AH, Ren C, Esrick EB, Manis JP, Dorfman DM, Williams DA, Biffi A, Brugnara C, Biasco L, Brendel C, Pinello L, Tsai SQ, Wolfe SA, Bauer DE Nature medicine 30911135 Nat Med 2019 May https://www.ncbi.nlm.nih.gov/pubmed/30911135
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM. Chen H, Albergante L, Hsu JY, Lareau CA, Lo Bosco G, Guan J, Zhou S, Gorban AN, Bauer DE, Aryee MJ, Langenau DM, Zinovyev A, Buenrostro JD, Yuan GC, Pinello L Nature communications 31015418 Nat Commun 2019 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/31015418
Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells. Nagpal N, Wang J, Zeng J, Lo E, Moon DH, Luk K, Braun RO, Burroughs LM, Keel SB, Reilly C, Lindsley RC, Wolfe SA, Tai AK, Cahan P, Bauer DE, Fong YW, Agarwal S Cell stem cell 32320679 Cell Stem Cell 2020 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/32320679
A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and Their Differentiated Derivatives. El-Nachef D, Shi K, Beussman KM, Martinez R, Regier MC, Everett GW, Murry CE, Stevens KR, Young JE, Sniadecki NJ, Davis J Stem cell reports 32619493 Stem Cell Reports 2020 Jul 14 https://www.ncbi.nlm.nih.gov/pubmed/32619493
Human Pluripotent Stem Cell-Derived Engineered Tissues: Clinical Considerations. Stevens KR, Murry CE Cell stem cell 29499147 Cell Stem Cell 2018 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/29499147
Guided vascularization in the rat heart leads to transient vessel patterning. Brady EL, Kirby MA, Olszewski E, Grosjean P, Johansson F, Davis J, Wang RK, Stevens KR APL bioengineering 32161835 APL Bioeng 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/32161835
Photopatterned biomolecule immobilization to guide three-dimensional cell fate in natural protein-based hydrogels. Batalov I, Stevens KR, DeForest CA Proceedings of the National Academy of Sciences of the United States of America 33468675 Proc Natl Acad Sci U S A 2021 Jan 26 https://www.ncbi.nlm.nih.gov/pubmed/33468675
User-defined morphogen patterning for directing human cell fate stratification. Regier MC, Tokar JJ, Warrick JW, Pabon L, Berthier E, Beebe DJ, Stevens KR Scientific reports 31015521 Sci Rep 2019 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/31015521
Author Correction: Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates. Kinstlinger IS, Saxton SH, Calderon GA, Ruiz KV, Yalacki DR, Deme PR, Rosenkrantz JE, Louis-Rosenberg JD, Johansson F, Janson KD, Sazer DW, Panchavati SS, Bissig KD, Stevens KR, Miller JS Nature biomedical engineering 34135476 Nat Biomed Eng 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34135476
A FRESH Take on Resolution in 3D Bioprinting. Corbett DC, Olszewski E, Stevens K Trends in biotechnology 31623960 Trends Biotechnol 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31623960
Infarct Collagen Topography Regulates Fibroblast Fate via p38-Yes-Associated Protein Transcriptional Enhanced Associate Domain Signals. Bugg D, Bretherton R, Kim P, Olszewski E, Nagle A, Schumacher AE, Chu N, Gunaje J, DeForest CA, Stevens K, Kim DH, Davis J Circulation research 32883176 Circ Res 2020 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/32883176
Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates. Kinstlinger IS, Saxton SH, Calderon GA, Ruiz KV, Yalacki DR, Deme PR, Rosenkrantz JE, Louis-Rosenberg JD, Johansson F, Janson KD, Sazer DW, Panchavati SS, Bissig KD, Stevens KR, Miller JS Nature biomedical engineering 32601395 Nat Biomed Eng 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32601395
Embryo-scale, single-cell spatial transcriptomics. Srivatsan SR, Regier MC, Barkan E, Franks JM, Packer JS, Grosjean P, Duran M, Saxton S, Ladd JJ, Spielmann M, Lois C, Lampe PD, Shendure J, Stevens KR, Trapnell C Science (New York, N.Y.) 34210887 Science 2021 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/34210887
Engineered tissue vascularization and engraftment depends on host model. Brady EL, Prado O, Johansson F, Mitchell SN, Martinson AM, Karbassi E, Reinecke H, Murry CE, Davis J, Stevens KR Scientific reports 36737618 Sci Rep 2023 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/36737618
Thermofluidic heat exchangers for actuation of transcription in artificial tissues. Corbett DC, Fabyan WB, Grigoryan B, O'Connor CE, Johansson F, Batalov I, Regier MC, DeForest CA, Miller JS, Stevens KR Science advances 32998880 Sci Adv 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32998880
Spatial presentation of biological molecules to cells by localized diffusive transfer. Regier MC, Olszewski E, Carter CC, Aitchison JD, Kaushansky A, Davis J, Berthier E, Beebe DJ, Stevens KR Lab on a chip 31111131 Lab Chip 2019 Jun 11 https://www.ncbi.nlm.nih.gov/pubmed/31111131
Multivascular networks and functional intravascular topologies within biocompatible hydrogels. Grigoryan B, Paulsen SJ, Corbett DC, Sazer DW, Fortin CL, Zaita AJ, Greenfield PT, Calafat NJ, Gounley JP, Ta AH, Johansson F, Randles A, Rosenkrantz JE, Louis-Rosenberg JD, Galie PA, Stevens KR, Miller JS Science (New York, N.Y.) 31048486 Science 2019 May 3 https://www.ncbi.nlm.nih.gov/pubmed/31048486
Human Organ-Specific Endothelial Cell Heterogeneity. Marcu R, Choi YJ, Xue J, Fortin CL, Wang Y, Nagao RJ, Xu J, MacDonald JW, Bammler TK, Murry CE, Muczynski K, Stevens KR, Himmelfarb J, Schwartz SM, Zheng Y iScience 30240741 iScience 2018 Jun 29 https://www.ncbi.nlm.nih.gov/pubmed/30240741
Engineering Heart Morphogenesis. Mandrycky CJ, Williams NP, Batalov I, El-Nachef D, de Bakker BS, Davis J, Kim DH, DeForest CA, Zheng Y, Stevens KR, Sniadecki NJ Trends in biotechnology 32673587 Trends Biotechnol 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32673587
Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions. Lemaster JE, Jeevarathinam AS, Kumar A, Chandrasekar B, Chen F, Jokerst JV ACS applied bio materials 31930189 ACS Appl Bio Mater 2019 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/31930189
Increasing the Efficacy of Stem Cell Therapy via Triple-Function Inorganic Nanoparticles. Chen F, Zhao ER, Hableel G, Hu T, Kim T, Li J, Gonzalez-Pech NI, Cheng DJ, Lemaster JE, Xie Y, Grassian VH, Sen GL, Jokerst JV ACS nano 31188564 ACS Nano 2019 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/31188564
The characterization of an economic and portable LED-based photoacoustic imaging system to facilitate molecular imaging. Hariri A, Lemaster J, Wang J, Jeevarathinam AS, Chao DL, Jokerst JV Photoacoustics 29234601 Photoacoustics 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29234601
Photoacoustic Imaging for Noninvasive Periodontal Probing Depth Measurements. Lin CY, Chen F, Hariri A, Chen CJ, Wilder-Smith P, Takesh T, Jokerst JV Journal of dental research 28880116 J Dent Res 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/28880116
Deep learning improves contrast in low-fluence photoacoustic imaging. Hariri A, Alipour K, Mantri Y, Schulze JP, Jokerst JV Biomedical optics express 32637260 Biomed Opt Express 2020 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/32637260
Phenolic-enabled nanotechnology: versatile particle engineering for biomedicine. Wu D , Zhou J , Creyer MN , Yim W , Chen Z , Messersmith PB , Jokerst JV Chemical Society reviews 33595004 Chem Soc Rev 2021 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/33595004
Enhanced Photoacoustic Detection of Heparin in Whole Blood via Melanin Nanocapsules Carrying Molecular Agents. Yim W, Takemura K, Zhou J, Zhou J, Jin Z, Borum RM, Xu M, Cheng Y, He T, Penny W, Miller BR 3rd, Jokerst JV ACS nano 34962765 ACS Nano 2022 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/34962765
A Photoacoustic Contrast Agent for miR-21 via NIR Fluorescent Hybridization Chain Reaction. Borum RM, Moore C, Chan SK, Steinmetz NF, Jokerst JV Bioconjugate chemistry 34406744 Bioconjug Chem 2022 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/34406744
Photoacoustic Imaging of Human Mesenchymal Stem Cells Labeled with Prussian Blue-Poly(l-lysine) Nanocomplexes. Kim T, Lemaster JE, Chen F, Li J, Jokerst JV ACS nano 28759195 ACS Nano 2017 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/28759195
A cellulose-based photoacoustic sensor to measure heparin concentration and activity in human blood samples. Jeevarathinam AS, Pai N, Huang K, Hariri A, Wang J, Bai Y, Wang L, Hancock T, Keys S, Penny W, Jokerst JV Biosensors & bioelectronics 30602265 Biosens Bioelectron 2019 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/30602265
Hybridizing clinical translatability with enzyme-free DNA signal amplifiers: recent advances in nucleic acid detection and imaging. Borum RM , Jokerst JV Biomaterials science 32734995 Biomater Sci 2021 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/32734995
Organosilica Nanoparticles with an Intrinsic Secondary Amine: An Efficient and Reusable Adsorbent for Dyes. Chen F, Zhao E, Kim T, Wang J, Hableel G, Reardon PJT, Ananthakrishna SJ, Wang T, Arconada-Alvarez S, Knowles JC, Jokerst JV ACS applied materials & interfaces 28422482 ACS Appl Mater Interfaces 2017 May 10 https://www.ncbi.nlm.nih.gov/pubmed/28422482
In vivo photoacoustic imaging of chorioretinal oxygen gradients. Hariri A, Wang J, Kim Y, Jhunjhunwala A, Chao DL, Jokerst JV Journal of biomedical optics 29524321 J Biomed Opt 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29524321
Switchable Photoacoustic Intensity of Methylene Blue via Sodium Dodecyl Sulfate Micellization. Wang J, Lin CY, Moore C, Jhunjhunwala A, Jokerst JV Langmuir : the ACS journal of surfaces and colloids 29232146 Langmuir 2018 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/29232146
Listening for the therapeutic window: Advances in drug delivery utilizing photoacoustic imaging. Moore C, Chen F, Wang J, Jokerst JV Advanced drug delivery reviews 31295522 Adv Drug Deliv Rev 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/31295522
Cellular toxicity of silicon carbide nanomaterials as a function of morphology. Chen F, Li G, Zhao ER, Li J, Hableel G, Lemaster JE, Bai Y, Sen GL, Jokerst JV Biomaterials 29980075 Biomaterials 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/29980075
Versatile Polymer Nanocapsules via Redox Competition. Zhou J, Xu M, Jin Z, Borum RM, Avakyan N, Cheng Y, Yim W, He T, Zhou J, Wu Z, Mantri Y, Jokerst JV Angewandte Chemie (International ed. in English) 34580967 Angew Chem Int Ed Engl 2021 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/34580967
The in vivo fate of tobacco mosaic virus nanoparticle theranostic agents modified by the addition of a polydopamine coat. Nkanga CI, Chung YH, Shukla S, Zhou J, Jokerst JV, Steinmetz NF Biomaterials science 34591046 Biomater Sci 2021 Oct 26 https://www.ncbi.nlm.nih.gov/pubmed/34591046
Motion-compensated noninvasive periodontal health monitoring using handheld and motor-based photoacoustic-ultrasound imaging systems. Mozaffarzadeh M, Moore C, Golmoghani EB, Mantri Y, Hariri A, Jorns A, Fu L, Verweij MD, Orooji M, de Jong N, Jokerst JV Biomedical optics express 33796371 Biomed Opt Express 2021 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/33796371
Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity. Moore C, Borum RM, Mantri Y, Xu M, Fajtová P, O'Donoghue AJ, Jokerst JV ACS sensors 34038103 ACS Sens 2021 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/34038103
Stereoselective Growth of Small Molecule Patches on Nanoparticles. Zhou J, Creyer MN, Chen A, Yim W, Lafleur RPM, He T, Lin Z, Xu M, Abbasi P, Wu J, Pascal TA, Caruso F, Jokerst JV Journal of the American Chemical Society 34270250 J Am Chem Soc 2021 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/34270250
Ultrasmall gold nanorod-polydopamine hybrids for enhanced photoacoustic imaging and photothermal therapy in second near-infrared window. Yim W, Borum RM, Zhou J, Mantri Y, Wu Z, Zhou J, Jin Z, Creyer M, Jokerst JV Nanotheranostics 34976582 Nanotheranostics 2022 https://www.ncbi.nlm.nih.gov/pubmed/34976582
Copper Sulfide Nanodisks and Nanoprisms for Photoacoustic Ovarian Tumor Imaging. Wang J, Hsu SW, Gonzalez-Pech N, Jhunjhunwala A, Chen F, Hariri A, Grassian V, Tao A, Jokerst JV Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems 32863594 Part Part Syst Charact 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/32863594
Assessment of Respiratory Droplet Transmission During the Ophthalmic Slit-Lamp Exam: A Particle Tracking Analysis. Shah SH, Garg AK, Patel S, Yim W, Jokerst JV, Chao DL American journal of ophthalmology 32980331 Am J Ophthalmol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/32980331
Assessing the Physiological Relevance of Cough Simulators for Respiratory Droplet Dispersion. Patel SH, Yim W, Garg AK, Shah SH, Jokerst JV, Chao DL Journal of clinical medicine 32957639 J Clin Med 2020 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/32957639
Silicon Carbide Nanoparticles as a Photoacoustic and Photoluminescent Dual-Imaging Contrast Agent for Long-Term Cell Tracking. Chen F, Zhao ER, Hu T, Shi Y, Sirbuly DJ, Jokerst JV Nanoscale advances 33313479 Nanoscale Adv 2019 https://www.ncbi.nlm.nih.gov/pubmed/33313479
A Photoacoustic-Fluorescent Imaging Probe for Proteolytic Gingipains Expressed by Porphyromonas gingivalis. Moore C, Cheng Y, Tjokro N, Zhang B, Kerr M, Hayati M, Chang KCJ, Shah N, Chen C, Jokerst JV Angewandte Chemie (International ed. in English) 35583940 Angew Chem Int Ed Engl 2022 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/35583940
Dictionary learning technique enhances signal in LED-based photoacoustic imaging. Farnia P, Najafzadeh E, Hariri A, Lavasani SN, Makkiabadi B, Ahmadian A, Jokerst JV Biomedical optics express 32499941 Biomed Opt Express 2020 May 1 https://www.ncbi.nlm.nih.gov/pubmed/32499941
Iodide-doped precious metal nanoparticles: measuring oxidative stress in vivo via photoacoustic imaging. Mantri Y, Davidi B, Lemaster JE, Hariri A, Jokerst JV Nanoscale 32396928 Nanoscale 2020 May 21 https://www.ncbi.nlm.nih.gov/pubmed/32396928
A Gold/Silver Hybrid Nanoparticle for Treatment and Photoacoustic Imaging of Bacterial Infection. Kim T, Zhang Q, Li J, Zhang L, Jokerst JV ACS nano 29746090 ACS Nano 2018 Jun 26 https://www.ncbi.nlm.nih.gov/pubmed/29746090
Peptide-Induced Fractal Assembly of Silver Nanoparticles for Visual Detection of Disease Biomarkers. Retout M, Mantri Y, Jin Z, Zhou J, Noël G, Donovan B, Yim W, Jokerst JV ACS nano 35377141 ACS Nano 2022 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/35377141
Synchronization of RF Data in Ultrasound Open Platforms (UOPs) for High-Accuracy and High-Resolution Photoacoustic Tomography Using the "Scissors" Programming Method. Fu L, Jin Z, Qi B, Yim W, Wu Z, He T, Jokerst JV IEEE transactions on ultrasonics, ferroelectrics, and frequency control 35377843 IEEE Trans Ultrason Ferroelectr Freq Control 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35377843
Gold nanoparticles to enhance ophthalmic imaging. Chen F , Si P , de la Zerda A , Jokerst JV , Myung D Biomaterials science 33057463 Biomater Sci 2021 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/33057463
KN95 and N95 Respirators Retain Filtration Efficiency despite a Loss of Dipole Charge during Decontamination. Yim W, Cheng D, Patel SH, Kou R, Meng YS, Jokerst JV ACS applied materials & interfaces 33253527 ACS Appl Mater Interfaces 2020 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/33253527
A fiber optic photoacoustic sensor for real-time heparin monitoring. Zhou J, Yim W, Zhou J, Jin Z, Xu M, Mantri Y, He T, Cheng Y, Fu L, Wu Z, Hancock T, Penny W, Jokerst JV Biosensors & bioelectronics 34653712 Biosens Bioelectron 2022 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/34653712
A Wearable Colorimetric Dosimeter to Monitor Sunlight Exposure. Wang J, Jeevarathinam AS, Jhunjhunwala A, Ren H, Lemaster J, Luo Y, Fenning DP, Fullerton EE, Jokerst JV Advanced materials technologies 33928184 Adv Mater Technol 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/33928184
Photoacoustic imaging with fiber optic technology: A review. Zhou J, Jokerst JV Photoacoustics 33163358 Photoacoustics 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33163358
Exosome-like silica nanoparticles: a novel ultrasound contrast agent for stem cell imaging. Chen F, Ma M, Wang J, Wang F, Chern SX, Zhao ER, Jhunjhunwala A, Darmadi S, Chen H, Jokerst JV Nanoscale 27924340 Nanoscale 2017 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/27924340
Gold Nanorod-Melanin Hybrids for Enhanced and Prolonged Photoacoustic Imaging in the Near-Infrared-II Window. Yim W, Zhou J, Mantri Y, Creyer MN, Moore CA, Jokerst JV ACS applied materials & interfaces 33761255 ACS Appl Mater Interfaces 2021 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/33761255
Gadolinium Doping Enhances the Photoacoustic Signal of Synthetic Melanin Nanoparticles: A Dual Modality Contrast Agent for Stem Cell Imaging. Lemaster JE, Wang Z, Hariri A, Chen F, Hu Z, Huang Y, Barback CV, Cochran R, Gianneschi NC, Jokerst JV Chemistry of materials : a publication of the American Chemical Society 33859455 Chem Mater 2019 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/33859455
Simultaneous Enhancement of Photoluminescence, MRI Relaxivity, and CT Contrast by Tuning the Interfacial Layer of Lanthanide Heteroepitaxial Nanoparticles. He S, Johnson NJJ, Nguyen Huu VA, Cory E, Huang Y, Sah RL, Jokerst JV, Almutairi A Nano letters 28657755 Nano Lett 2017 Aug 9 https://www.ncbi.nlm.nih.gov/pubmed/28657755
Polyphenol-stabilized coacervates for enzyme-triggered drug delivery. Yim W, Jin Z, Chang YC, Brambila C, Creyer MN, Ling C, He T, Li Y, Retout M, Penny WF, Zhou J, Jokerst JV Nature communications 39181884 Nat Commun 2024 Aug 24 https://www.ncbi.nlm.nih.gov/pubmed/39181884
Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system. Hariri A, Zhao E, Jeevarathinam AS, Lemaster J, Zhang J, Jokerst JV Scientific reports 31388020 Sci Rep 2019 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/31388020
Tuning the ultrasonic and photoacoustic response of polydopamine-stabilized perfluorocarbon contrast agents. Xie Y, Wang J, Wang J, Hu Z, Hariri A, Tu N, Krug KA, Burkart MD, Gianneschi NC, Jokerst JV, Rinehart JD Journal of materials chemistry. B 31389967 J Mater Chem B 2019 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/31389967
A Nanoscale Tool for Photoacoustic-Based Measurements of Clotting Time and Therapeutic Drug Monitoring of Heparin. Wang J, Chen F, Arconada-Alvarez SJ, Hartanto J, Yap LP, Park R, Wang F, Vorobyova I, Dagliyan G, Conti PS, Jokerst JV Nano letters 27668964 Nano Lett 2016 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/27668964
The development and characterization of a novel yet simple 3D printed tool to facilitate phantom imaging of photoacoustic contrast agents. Arconada-Alvarez SJ, Lemaster JE, Wang J, Jokerst JV Photoacoustics 28239554 Photoacoustics 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28239554
Development of a Trimodal Contrast Agent for Acoustic and Magnetic Particle Imaging of Stem Cells. Lemaster JE, Chen F, Kim T, Hariri A, Jokerst JV ACS applied nano materials 33860154 ACS Appl Nano Mater 2018 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/33860154
Smart-Dust-Nanorice for Enhancement of Endogenous Raman Signal, Contrast in Photoacoustic Imaging, and T2-Shortening in Magnetic Resonance Imaging. Pohling C, Campbell JL, Larson TA, Van de Sompel D, Levi J, Bachmann MH, Bohndiek SE, Jokerst JV, Gambhir SS Small (Weinheim an der Bergstrasse, Germany) 29635739 Small 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29635739
A Mechanistic Investigation of Methylene Blue and Heparin Interactions and Their Photoacoustic Enhancement. Wang J, Jeevarathinam AS, Humphries K, Jhunjhunwala A, Chen F, Hariri A, Miller BR 3rd, Jokerst JV Bioconjugate chemistry 30281976 Bioconjug Chem 2018 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/30281976
Optics-Free, Non-Contact Measurements of Fluids, Bubbles, and Particles in Microchannels Using Metallic Nano-Islands on Graphene. Dhong C, Edmunds SJ, Ramírez J, Kayser LV, Chen F, Jokerst JV, Lipomi DJ Nano letters 30024767 Nano Lett 2018 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/30024767
Multifunctional nanomedicine with silica: Role of silica in nanoparticles for theranostic, imaging, and drug monitoring. Chen F, Hableel G, Zhao ER, Jokerst JV Journal of colloid and interface science 29510868 J Colloid Interface Sci 2018 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/29510868
Noninvasive staging of pressure ulcers using photoacoustic imaging. Hariri A, Chen F, Moore C, Jokerst JV Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 31301258 Wound Repair Regen 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31301258
Photoacoustic Imaging Quantifies Drug Release from Nanocarriers via Redox Chemistry of Dye-Labeled Cargo. Jeevarathinam AS, Lemaster JE, Chen F, Zhao E, Jokerst JV Angewandte Chemie (International ed. in English) 31840357 Angew Chem Int Ed Engl 2020 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/31840357
Enhanced Performance of a Molecular Photoacoustic Imaging Agent by Encapsulation in Mesoporous Silicon Nanoparticles. Kang J, Kim D, Wang J, Han Y, Zuidema JM, Hariri A, Park JH, Jokerst JV, Sailor MJ Advanced materials (Deerfield Beach, Fla.) 29782671 Adv Mater 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29782671
Photoacoustic imaging for monitoring periodontal health: A first human study. Moore C, Bai Y, Hariri A, Sanchez JB, Lin CY, Koka S, Sedghizadeh P, Chen C, Jokerst JV Photoacoustics 30450281 Photoacoustics 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30450281
Strategies for Image-Guided Therapy, Surgery, and Drug Delivery Using Photoacoustic Imaging. Moore C, Jokerst JV Theranostics 31037123 Theranostics 2019 https://www.ncbi.nlm.nih.gov/pubmed/31037123
Multispectral Nanoparticle Tracking Analysis for the Real-Time and Label-Free Characterization of Amyloid-β Self-Assembly In Vitro. Moore C, Wing R, Pham T, Jokerst JV Analytical chemistry 32786456 Anal Chem 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/32786456
Stem Cell Tracking with Nanoparticle-Based Ultrasound Contrast Agents. Chen F, Jokerst JV Methods in molecular biology (Clifton, N.J.) 32112386 Methods Mol Biol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32112386
Engineering Plasmonic Nanoparticles for Enhanced Photoacoustic Imaging. Mantri Y, Jokerst JV ACS nano 32806027 ACS Nano 2020 Aug 25 https://www.ncbi.nlm.nih.gov/pubmed/32806027
A Protease-Responsive Polymer/Peptide Conjugate and Reversible Assembly of Silver Clusters for the Detection of Porphyromonas gingivalis Enzymatic Activity. Retout M, Amer L, Yim W, Creyer MN, Lam B, Trujillo DF, Potempa J, O'Donoghue AJ, Chen C, Jokerst JV ACS nano 37602819 ACS Nano 2023 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/37602819
Robust and Versatile Coatings Engineered via Simultaneous Covalent and Noncovalent Interactions. Zhou J, Penna M, Lin Z, Han Y, Lafleur RPM, Qu Y, Richardson JJ, Yarovsky I, Jokerst JV, Caruso F Angewandte Chemie (International ed. in English) 34258845 Angew Chem Int Ed Engl 2021 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/34258845
Supramolecular Loading of DNA Hydrogels with Dye-Drug Conjugates for Real-Time Photoacoustic Monitoring of Chemotherapy. Borum RM, Moore C, Mantri Y, Xu M, Jokerst JV Advanced science (Weinheim, Baden-Wurttemberg, Germany) 36403233 Adv Sci (Weinh) 2022 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/36403233
Cryo-electron tomography with mixed-scale dense neural networks reveals key steps in deployment of Toxoplasma invasion machinery. Segev-Zarko LA, Dahlberg PD, Sun SY, Pelt DM, Kim CY, Egan ES, Sethian JA, Chiu W, Boothroyd JC PNAS nexus 36329726 PNAS Nexus 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/36329726
Cryogenic electron tomography reveals novel structures in the apical complex of Plasmodium falciparum. Sun SY, Segev-Zarko L-a, Pintilie GD, Kim CY, Staggers SR, Schmid MF, Egan ES, Chiu W, Boothroyd JC mBio 38456679 mBio 2024 Apr 10 https://www.ncbi.nlm.nih.gov/pubmed/38456679
A common polymorphism in the mechanosensitive ion channel PIEZO1 is associated with protection from severe malaria in humans. Nguetse CN, Purington N, Ebel ER, Shakya B, Tetard M, Kremsner PG, Velavan TP, Egan ES Proceedings of the National Academy of Sciences of the United States of America 32265284 Proc Natl Acad Sci U S A 2020 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/32265284
Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasion. Baro B, Kim CY, Lin C, Kongsomboonvech AK, Tetard M, Peterson NA, Salinas ND, Tolia NH, Egan ES Blood 37832027 Blood 2023 Dec 7 https://www.ncbi.nlm.nih.gov/pubmed/37832027
Erythrocyte CD55 mediates the internalization of Plasmodium falciparum parasites. Shakya B, Patel SD, Tani Y, Egan ES eLife 34028351 Elife 2021 May 24 https://www.ncbi.nlm.nih.gov/pubmed/34028351
Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum. Egan ES, Weekes MP, Kanjee U, Manzo J, Srinivasan A, Lomas-Francis C, Westhoff C, Takahashi J, Tanaka M, Watanabe S, Brugnara C, Gygi SP, Tani Y, Duraisingh MT Communications biology 30271928 Commun Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30271928
Beyond Hemoglobin: Screening for Malaria Host Factors. Egan ES Trends in genetics : TIG 29249333 Trends Genet 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29249333
Uncovering a Cryptic Site of Malaria Pathogenesis: Models to Study Interactions Between Plasmodium and the Bone Marrow. Feldman TP, Egan ES Frontiers in cellular and infection microbiology 35719356 Front Cell Infect Microbiol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35719356
Revisiting the malaria hypothesis: accounting for polygenicity and pleiotropy. Ebel ER, Uricchio LH, Petrov DA, Egan ES Trends in parasitology 35065882 Trends Parasitol 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35065882
CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion. Mou H, Smith JL, Peng L, Yin H, Moore J, Zhang XO, Song CQ, Sheel A, Wu Q, Ozata DM, Li Y, Anderson DG, Emerson CP, Sontheimer EJ, Moore MJ, Weng Z, Xue W Genome biology 28615073 Genome Biol 2017 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/28615073
Depletion of TRRAP Induces p53-Independent Senescence in Liver Cancer by Down-Regulating Mitotic Genes. Kwan SY, Sheel A, Song CQ, Zhang XO, Jiang T, Dang H, Cao Y, Ozata DM, Mou H, Yin H, Weng Z, Wang XW, Xue W Hepatology (Baltimore, Md.) 31188495 Hepatology 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31188495
A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver. Zheng C, Liang SQ, Liu B, Liu P, Kwan SY, Wolfe SA, Xue W Molecular therapy : the journal of the American Society of Gene Therapy 34998953 Mol Ther 2022 Mar 2 https://www.ncbi.nlm.nih.gov/pubmed/34998953
A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing. Edraki A, Mir A, Ibraheim R, Gainetdinov I, Yoon Y, Song CQ, Cao Y, Gallant J, Xue W, Rivera-Pérez JA, Sontheimer EJ Molecular cell 30581144 Mol Cell 2019 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/30581144
In Vivo Genome Editing Partially Restores Alpha1-Antitrypsin in a Murine Model of AAT Deficiency. Song CQ, Wang D, Jiang T, O'Connor K, Tang Q, Cai L, Li X, Weng Z, Yin H, Gao G, Mueller C, Flotte TR, Xue W Human gene therapy 29597895 Hum Gene Ther 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29597895
Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function. Jiang T, Sánchez-Rivera FJ, Soto-Feliciano YM, Yang Q, Song CQ, Bhuatkar A, Haynes CM, Hemann MT, Xue W Hepatology (Baltimore, Md.) 33336367 Hepatology 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/33336367
Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice. Song CQ, Li Y, Mou H, Moore J, Park A, Pomyen Y, Hough S, Kennedy Z, Fischer A, Yin H, Anderson DG, Conte D Jr, Zender L, Wang XW, Thorgeirsson S, Weng Z, Xue W Gastroenterology 27956228 Gastroenterology 2017 Apr https://www.ncbi.nlm.nih.gov/pubmed/27956228
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity. Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG Nature chemical biology 29377001 Nat Chem Biol 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29377001
CRISPR-Cas-related technologies in basic and translational liver research. Song CQ, Xue W Nature reviews. Gastroenterology & hepatology 29443117 Nat Rev Gastroenterol Hepatol 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29443117
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice. Wang D, Li J, Song CQ, Tran K, Mou H, Wu PH, Tai PWL, Mendonca CA, Ren L, Wang BY, Su Q, Gessler DJ, Zamore PD, Xue W, Gao G Nature biotechnology 30102296 Nat Biotechnol 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30102296
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo. Ibraheim R, Tai PWL, Mir A, Javeed N, Wang J, Rodríguez TC, Namkung S, Nelson S, Khokhar ES, Mintzer E, Maitland S, Chen Z, Cao Y, Tsagkaraki E, Wolfe SA, Wang D, Pai AA, Xue W, Gao G, Sontheimer EJ Nature communications 34725353 Nat Commun 2021 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/34725353
Genome-wide detection of CRISPR editing in vivo using GUIDE-tag. Liang SQ, Liu P, Smith JL, Mintzer E, Maitland S, Dong X, Yang Q, Lee J, Haynes CM, Zhu LJ, Watts JK, Sontheimer EJ, Wolfe SA, Xue W Nature communications 35064134 Nat Commun 2022 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/35064134
CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling. Mou H, Ozata DM, Smith JL, Sheel A, Kwan SY, Hough S, Kucukural A, Kennedy Z, Cao Y, Xue W Genome medicine 30987660 Genome Med 2019 Apr 16 https://www.ncbi.nlm.nih.gov/pubmed/30987660
Multiomics characterization of mouse hepatoblastoma identifies yes-associated protein 1 target genes. Rodríguez TC, Kwan SY, Smith JL, Dadafarin S, Wu CH, Sontheimer EJ, Xue W Hepatology (Baltimore, Md.) 35932276 Hepatology 2023 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/35932276
Adenine base editing in an adult mouse model of tyrosinaemia. Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W Nature biomedical engineering 31740768 Nat Biomed Eng 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31740768
Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope. Jiang T, Henderson JM, Coote K, Cheng Y, Valley HC, Zhang XO, Wang Q, Rhym LH, Cao Y, Newby GA, Bihler H, Mense M, Weng Z, Anderson DG, McCaffrey AP, Liu DR, Xue W Nature communications 32332735 Nat Commun 2020 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/32332735
Deletion and replacement of long genomic sequences using prime editing. Jiang T, Zhang XO, Weng Z, Xue W Nature biotechnology 34650270 Nat Biotechnol 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/34650270
Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag. Liang SQ, Liu P, Ponnienselvan K, Suresh S, Chen Z, Kramme C, Chatterjee P, Zhu LJ, Sontheimer EJ, Xue W, Wolfe SA Nature methods 37156841 Nat Methods 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/37156841
YAP1 Withdrawal in Hepatoblastoma Drives Therapeutic Differentiation of Tumor Cells to Functional Hepatocyte-Like Cells. Smith JL, Rodríguez TC, Mou H, Kwan SY, Pratt H, Zhang XO, Cao Y, Liang S, Ozata DM, Yu T, Yin Q, Hazeltine M, Weng Z, Sontheimer EJ, Xue W Hepatology (Baltimore, Md.) 32452550 Hepatology 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/32452550
The temporal landscape of recursive splicing during Pol II transcription elongation in human cells. Zhang XO, Fu Y, Mou H, Xue W, Weng Z PLoS genetics 30148885 PLoS Genet 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/30148885
A split prime editor with untethered reverse transcriptase and circular RNA template. Liu B, Dong X, Cheng H, Zheng C, Chen Z, Rodríguez TC, Liang SQ, Xue W, Sontheimer EJ Nature biotechnology 35379962 Nat Biotechnol 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35379962
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice. Liu P, Liang SQ, Zheng C, Mintzer E, Zhao YG, Ponnienselvan K, Mir A, Sontheimer EJ, Gao G, Flotte TR, Wolfe SA, Xue W Nature communications 33837189 Nat Commun 2021 Apr 9 https://www.ncbi.nlm.nih.gov/pubmed/33837189
Understanding and repurposing CRISPR-mediated alternative splicing. Smith JL, Mou H, Xue W Genome biology 30400804 Genome Biol 2018 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/30400804
All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo. Ibraheim R, Song CQ, Mir A, Amrani N, Xue W, Sontheimer EJ Genome biology 30231914 Genome Biol 2018 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/30231914
Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing. Li B, Manan RS, Liang SQ, Gordon A, Jiang A, Varley A, Gao G, Langer R, Xue W, Anderson D Nature biotechnology 36997680 Nat Biotechnol 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/36997680
Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis. Mou H, Moore J, Malonia SK, Li Y, Ozata DM, Hough S, Song CQ, Smith JL, Fischer A, Weng Z, Green MR, Xue W Proceedings of the National Academy of Sciences of the United States of America 28320962 Proc Natl Acad Sci U S A 2017 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/28320962
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing. Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson DG Nature biotechnology 29131148 Nat Biotechnol 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/29131148
Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins. Lee J, Mou H, Ibraheim R, Liang SQ, Liu P, Xue W, Sontheimer EJ RNA (New York, N.Y.) 31439808 RNA 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31439808
Advances in CRISPR/Cas-based Gene Therapy in Human Genetic Diseases. Wu SS, Li QC, Yin CQ, Xue W, Song CQ Theranostics 32292501 Theranostics 2020 https://www.ncbi.nlm.nih.gov/pubmed/32292501
AAV5 Delivery of CRISPR/Cas9 Mediates Genome Editing in the Lungs of Young Rhesus Monkeys. Liang SQ, Navia AW, Ramseier M, Zhou X, Martinez M, Lee C, Zhou C, Wu J, Xie J, Su Q, Wang D, Flotte TR, Anderson DG, Tarantal AF, Shalek AK, Gao G, Xue W Human gene therapy 38767512 Hum Gene Ther 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/38767512
AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway. Liang SQ, Walkey CJ, Martinez AE, Su Q, Dickinson ME, Wang D, Lagor WR, Heaney JD, Gao G, Xue W Molecular therapy : the journal of the American Society of Gene Therapy 34695545 Mol Ther 2022 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/34695545
Template-jumping prime editing enables large insertion and exon rewriting in vivo. Zheng C, Liu B, Dong X, Gaston N, Sontheimer EJ, Xue W Nature communications 37291100 Nat Commun 2023 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/37291100
A salt-sensing kinase in T lymphocytes, SGK1, drives hypertension and hypertensive end-organ damage. Norlander AE, Saleh MA, Pandey AK, Itani HA, Wu J, Xiao L, Kang J, Dale BL, Goleva SB, Laroumanie F, Du L, Harrison DG, Madhur MS JCI insight 28679951 JCI Insight 2017 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/28679951
LNK deficiency promotes acute aortic dissection and rupture. Laroumanie F, Korneva A, Bersi MR, Alexander MR, Xiao L, Zhong X, Van Beusecum JP, Chen Y, Saleh MA, McMaster WG, Gavulic KA, Dale BL, Zhao S, Guo Y, Shyr Y, Perrien DS, Cox NJ, Curci JA, Humphrey JD, Madhur MS JCI insight 30333305 JCI Insight 2018 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/30333305
Immune profiling of murine cardiac leukocytes identifies triggering receptor expressed on myeloid cells 2 as a novel mediator of hypertensive heart failure. Smart CD, Fehrenbach DJ, Wassenaar JW, Agrawal V, Fortune NL, Dixon DD, Cottam MA, Hasty AH, Hemnes AR, Doran AC, Gupta DK, Madhur MS Cardiovascular research 37314125 Cardiovasc Res 2023 Oct 24 https://www.ncbi.nlm.nih.gov/pubmed/37314125
Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species. Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33015868 FASEB J 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33015868
The immunology of hypertension. Norlander AE, Madhur MS, Harrison DG The Journal of experimental medicine 29247045 J Exp Med 2018 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/29247045
From Rags to Riches: Moving Beyond RAG1 in Studies of Hypertension. Madhur MS, Kirabo A, Guzik TJ, Harrison DG Hypertension (Dallas, Tex. : 1979) 32078385 Hypertension 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32078385
Inflammation Resolution in the Cardiovascular System: Arterial Hypertension, Atherosclerosis, and Ischemic Heart Disease. Gonzalez AL, Dungan MM, Smart CD, Madhur MS, Doran AC Antioxidants & redox signaling 37125445 Antioxid Redox Signal 2024 Feb https://www.ncbi.nlm.nih.gov/pubmed/37125445
Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease. Wassenaar JW, Smart CD, Fehrenbach DJ, Agrawal V, Dungan MM, Fortune NL, Zhong L, Hemnes AR, Peebles RS Jr, Miller FJ Jr, Doran AC, Madhur MS JACC. Basic to translational science 39958476 JACC Basic Transl Sci 2025 Jan https://www.ncbi.nlm.nih.gov/pubmed/39958476
A Single Nucleotide Polymorphism in SH2B3/LNK Promotes Hypertension Development and Renal Damage. Alexander MR, Hank S, Dale BL, Himmel L, Zhong X, Smart CD, Fehrenbach DJ, Chen Y, Prabakaran N, Tirado B, Centrella M, Ao M, Du L, Shyr Y, Levy D, Madhur MS Circulation research 36169218 Circ Res 2022 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/36169218
Interleukin 17A: Key Player in the Pathogenesis of Hypertension and a Potential Therapeutic Target. Davis GK, Fehrenbach DJ, Madhur MS Current hypertension reports 33666761 Curr Hypertens Rep 2021 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/33666761
Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic? Madhur MS, Elijovich F, Alexander MR, Pitzer A, Ishimwe J, Van Beusecum JP, Patrick DM, Smart CD, Kleyman TR, Kingery J, Peck RN, Laffer CL, Kirabo A Circulation research 33793336 Circ Res 2021 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/33793336
Critical role of Interleukin 21 and T follicular helper cells in hypertension and vascular dysfunction. Dale BL, Pandey AK, Chen Y, Smart CD, Laroumanie F, Ao M, Xiao L, Dikalova AE, Dikalov SI, Elijovich F, Foss JD, Barbaro NR, Van Beusecum JP, Deger SM, Alsouqi A, Itani HA, Norlander AE, Alexander MR, Zhao S, Ikizler TA, Algood HMS, Madhur MS JCI insight 31013256 JCI Insight 2019 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/31013256
Human monocyte transcriptional profiling identifies IL-18 receptor accessory protein and lactoferrin as novel immune targets in hypertension. Alexander MR, Norlander AE, Elijovich F, Atreya RV, Gaye A, Gnecco JS, Laffer CL, Galindo CL, Madhur MS British journal of pharmacology 29774543 Br J Pharmacol 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/29774543
Status of Early-Career Academic Cardiology: A Global Perspective. Tong CW, Madhur MS, Rzeszut AK, Abdalla M, Abudayyeh I, Alexanderson E, Buber J, Feldman DN, Gopinathannair R, Hira RS, Kates AM, Kessler T, Leung S, Raj SR, Spatz ES, Turner MB, Valente AM, West K, Sivaram CA, Hill JA, Mann DL, Freeman AM Journal of the American College of Cardiology 29073958 J Am Coll Cardiol 2017 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/29073958
Evidence for a Causal Role of the SH2B3-β(2)M Axis in Blood Pressure Regulation. Keefe JA, Hwang SJ, Huan T, Mendelson M, Yao C, Courchesne P, Saleh MA, Madhur MS, Levy D Hypertension (Dallas, Tex. : 1979) 30624993 Hypertension 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30624993
Adaptive immune cells in calcific aortic valve disease. Raddatz MA, Madhur MS, Merryman WD American journal of physiology. Heart and circulatory physiology 31050556 Am J Physiol Heart Circ Physiol 2019 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/31050556
Class switching and high-affinity immunoglobulin G production by B cells is dispensable for the development of hypertension in mice. Chen Y, Dale BL, Alexander MR, Xiao L, Ao M, Pandey AK, Smart CD, Davis GK, Madhur MS Cardiovascular research 32609312 Cardiovasc Res 2021 Mar 21 https://www.ncbi.nlm.nih.gov/pubmed/32609312
Coordinate adaptations of skeletal muscle and kidney to maintain extracellular [K(+)] during K(+)-deficient diet. McFarlin BE, Chen Y, Priver TS, Ralph DL, Mercado A, Gamba G, Madhur MS, McDonough AA American journal of physiology. Cell physiology 32845718 Am J Physiol Cell Physiol 2020 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/32845718
COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Guzik TJ, Mohiddin SA, Dimarco A, Patel V, Savvatis K, Marelli-Berg FM, Madhur MS, Tomaszewski M, Maffia P, D'Acquisto F, Nicklin SA, Marian AJ, Nosalski R, Murray EC, Guzik B, Berry C, Touyz RM, Kreutz R, Wang DW, Bhella D, Sagliocco O, Crea F, Thomson EC, McInnes IB Cardiovascular research 32352535 Cardiovasc Res 2020 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/32352535
Super-Resolution Imaging of Self-Assembled Nanocarriers Using Quantitative Spectroscopic Analysis for Cluster Extraction. Davis JL, Zhang Y, Yi S, Du F, Song KH, Scott EA, Sun C, Zhang HF Langmuir : the ACS journal of surfaces and colloids 32069413 Langmuir 2020 Mar 10 https://www.ncbi.nlm.nih.gov/pubmed/32069413
Acute CD47 Blockade During Ischemic Myocardial Reperfusion Enhances Phagocytosis-Associated Cardiac Repair. Zhang S, Yeap XY, DeBerge M, Naresh NK, Wang K, Jiang Z, Wilcox JE, White SM, Morrow JP, Burridge PW, Procissi D, Scott EA, Frazier W, Thorp EB JACC. Basic to translational science 28920097 JACC Basic Transl Sci 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28920097
Tailoring Nanostructure Morphology for Enhanced Targeting of Dendritic Cells in Atherosclerosis. Yi S, Allen SD, Liu YG, Ouyang BZ, Li X, Augsornworawat P, Thorp EB, Scott EA ACS nano 27935698 ACS Nano 2016 Dec 27 https://www.ncbi.nlm.nih.gov/pubmed/27935698
Leveraging self-assembled nanobiomaterials for improved cancer immunotherapy. Vincent MP, Navidzadeh JO, Bobbala S, Scott EA Cancer cell 35148814 Cancer Cell 2022 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/35148814
Facile assembly and loading of theranostic polymersomes via multi-impingement flash nanoprecipitation. Allen S, Osorio O, Liu YG, Scott E Journal of controlled release : official journal of the Controlled Release Society 28736263 J Control Release 2017 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/28736263
Sustained micellar delivery via inducible transitions in nanostructure morphology. Karabin NB, Allen S, Kwon HK, Bobbala S, Firlar E, Shokuhfar T, Shull KR, Scott EA Nature communications 29434200 Nat Commun 2018 Feb 12 https://www.ncbi.nlm.nih.gov/pubmed/29434200
Influences of nanocarrier morphology on therapeutic immunomodulation. Frey M, Bobbala S, Karabin N, Scott E Nanomedicine (London, England) 30084296 Nanomedicine (Lond) 2018 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/30084296
The Combination of Morphology and Surface Chemistry Defines the Immunological Identity of Nanocarriers in Human Blood. Vincent MP, Karabin NB, Allen SD, Bobbala S, Frey MA, Yi S, Yang Y, Scott EA Advanced therapeutics 34485684 Adv Ther (Weinh) 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34485684
Dendritic peptide-conjugated polymeric nanovectors for non-toxic delivery of plasmid DNA and enhanced non-viral transfection of immune cells. Yi S, Kim SY, Vincent MP, Yuk SA, Bobbala S, Du F, Scott EA iScience 35769884 iScience 2022 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/35769884
Engineering nanomaterials to address cell-mediated inflammation in atherosclerosis. Allen S, Liu YG, Scott E Regenerative engineering and translational medicine 27135051 Regen Eng Transl Med 2016 Mar https://www.ncbi.nlm.nih.gov/pubmed/27135051
Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy. Vincent MP, Stack T, Vahabikashi A, Li G, Perkumas KM, Ren R, Gong H, Stamer WD, Johnson M, Scott EA ACS applied materials & interfaces 34232612 ACS Appl Mater Interfaces 2021 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/34232612
Just add water: hydratable, morphologically diverse nanocarrier powders for targeted delivery. Bobbala S, Vincent MP, Scott EA Nanoscale 34160529 Nanoscale 2021 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/34160529
Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability. Burke JA, Zhang X, Bobbala S, Frey MA, Bohorquez Fuentes C, Freire Haddad H, Allen SD, Richardson RAK, Ameer GA, Scott EA Nature nanotechnology 35039683 Nat Nanotechnol 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35039683
On the advancement of polymeric bicontinuous nanospheres toward biomedical applications. Allen SD, Bobbala S, Karabin NB, Scott EA Nanoscale horizons 32254084 Nanoscale Horiz 2019 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/32254084
Employment of targeted nanoparticles for imaging of cellular processes in cardiovascular disease. Modak M, Frey MA, Yi S, Liu Y, Scott EA Current opinion in biotechnology 32682272 Curr Opin Biotechnol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32682272
Minimizing Molecular Misidentification in Imaging Low-Abundance Protein Interactions Using Spectroscopic Single-Molecule Localization Microscopy. Zhang Y, Wang G, Huang P, Sun E, Kweon J, Li Q, Zhe J, Ying LL, Zhang HF Analytical chemistry 36165784 Anal Chem 2022 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/36165784
An Injectable Hydrogel Platform for Sustained Delivery of Anti-inflammatory Nanocarriers and Induction of Regulatory T Cells in Atherosclerosis. Yi S, Karabin NB, Zhu J, Bobbala S, Lyu H, Li S, Liu Y, Frey M, Vincent M, Scott EA Frontiers in bioengineering and biotechnology 32582667 Front Bioeng Biotechnol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32582667
Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis. Allen SD , Liu YG , Kim T , Bobbala S , Yi S , Zhang X , Choi J , Scott EA Biomaterials science 30601470 Biomater Sci 2019 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/30601470
Induction of Mycobacterium Tuberculosis Lipid-Specific T Cell Responses by Pulmonary Delivery of Mycolic Acid-Loaded Polymeric Micellar Nanocarriers. Shang S, Kats D, Cao L, Morgun E, Velluto D, He Y, Xu Q, Wang CR, Scott EA Frontiers in immunology 30538700 Front Immunol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30538700
Employing bicontinuous-to-micellar transitions in nanostructure morphology for on-demand photo-oxidation responsive cytosolic delivery and off-on cytotoxicity. Bobbala S, Allen SD, Yi S, Vincent M, Frey M, Karabin NB, Scott EA Nanoscale 32090217 Nanoscale 2020 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/32090217
Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation. Allen S, Vincent M, Scott E Journal of visualized experiments : JoVE 30148497 J Vis Exp 2018 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/30148497
Immunotheranostic Polymersomes Modularly Assembled from Tetrablock and Diblock Copolymers with Oxidation-Responsive Fluorescence. Du F, Liu YG, Scott EA Cellular and molecular bioengineering 28989540 Cell Mol Bioeng 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28989540
Modulation of Schlemm's canal endothelial cell stiffness via latrunculin loaded block copolymer micelles. Stack T, Vahabikashi A, Johnson M, Scott E Journal of biomedical materials research. Part A 29468812 J Biomed Mater Res A 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29468812
Surface engineered polymersomes for enhanced modulation of dendritic cells during cardiovascular immunotherapy. Yi S, Zhang X, Sangji H, Liu Y, Allen SD, Xiao B, Bobbala S, Braverman CL, Cai L, Hecker PI, DeBerge M, Thorp EB, Temel RE, Stupp SI, Scott EA Advanced functional materials 34335131 Adv Funct Mater 2019 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/34335131
Homopolymer self-assembly of poly(propylene sulfone) hydrogels via dynamic noncovalent sulfone-sulfone bonding. Du F, Qiao B, Nguyen TD, Vincent MP, Bobbala S, Yi S, Lescott C, Dravid VP, Olvera de la Cruz M, Scott EA Nature communications 32994414 Nat Commun 2020 Sep 29 https://www.ncbi.nlm.nih.gov/pubmed/32994414
Targeted Delivery of Cell Softening Micelles to Schlemm's Canal Endothelial Cells for Treatment of Glaucoma. Stack T, Vincent M, Vahabikashi A, Li G, Perkumas KM, Stamer WD, Johnson M, Scott E Small (Weinheim an der Bergstrasse, Germany) 33015961 Small 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/33015961
Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets. Vincent MP, Bobbala S, Karabin NB, Frey M, Liu Y, Navidzadeh JO, Stack T, Scott EA Nature communications 33510170 Nat Commun 2021 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/33510170
Enhancing subcutaneous injection and target tissue accumulation of nanoparticles via co-administration with macropinocytosis inhibitory nanoparticles (MiNP). Stack T, Liu Y, Frey M, Bobbala S, Vincent M, Scott E Nanoscale horizons 33884386 Nanoscale Horiz 2021 May 1 https://www.ncbi.nlm.nih.gov/pubmed/33884386
Sequential intracellular release of water-soluble cargos from Shell-crosslinked polymersomes. Du F, Bobbala S, Yi S, Scott EA Journal of controlled release : official journal of the Controlled Release Society 29601932 J Control Release 2018 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/29601932
Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection. Li X, Yi S, Scariot DB, Martinez SJ, Falk BA, Olson CL, Romano PS, Scott EA, Engman DM JCI insight 33986194 JCI Insight 2021 May 10 https://www.ncbi.nlm.nih.gov/pubmed/33986194
Flash nanoprecipitation permits versatile assembly and loading of polymeric bicontinuous cubic nanospheres. Bobbala S , Allen SD , Scott EA Nanoscale 29255814 Nanoscale 2018 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/29255814
Pi-stacking Enhances Stability, Scalability of Formation, Control over Flexibility and Circulation Time of Polymeric Filaments. Li S, Bobbala S, Vincent MP, Modak M, Liu Y, Scott EA Advanced nanobiomed research 34870281 Adv Nanobiomed Res 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34870281
Microstructural Infarct Border Zone Remodeling in the Post-infarct Swine Heart Measured by Diffusion Tensor MRI. Kung GL, Vaseghi M, Gahm JK, Shevtsov J, Garfinkel A, Shivkumar K, Ennis DB Frontiers in physiology 30246802 Front Physiol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30246802
Editorial Commentary: Chronic obstructive pulmonary disease and sudden cardiac death: Cause and effect or simply an association? Hoffman J, Vaseghi M Trends in cardiovascular medicine 27238054 Trends Cardiovasc Med 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27238054
Cardiac sympathetic denervation for intractable ventricular arrhythmias in Chagas disease. Saenz LC, Corrales FM, Bautista W, Traina M, Meymandi S, Rodriguez DA, Tellez LJ, Vaseghi M, Garcia F, Shivkumar K, Bradfield JS Heart rhythm 26969783 Heart Rhythm 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/26969783
Cardiac Sympathetic Denervation for Refractory Ventricular Arrhythmias. Vaseghi M, Barwad P, Malavassi Corrales FJ, Tandri H, Mathuria N, Shah R, Sorg JM, Gima J, Mandal K, Sàenz Morales LC, Lokhandwala Y, Shivkumar K Journal of the American College of Cardiology 28641796 J Am Coll Cardiol 2017 Jun 27 https://www.ncbi.nlm.nih.gov/pubmed/28641796
Cardiac sympathetic innervation via middle cervical and stellate ganglia and antiarrhythmic mechanism of bilateral stellectomy. Irie T, Yamakawa K, Hamon D, Nakamura K, Shivkumar K, Vaseghi M American journal of physiology. Heart and circulatory physiology 28011590 Am J Physiol Heart Circ Physiol 2017 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/28011590
Outcomes of Catheter Ablation of Ventricular Tachycardia Based on Etiology in Nonischemic Heart Disease: An International Ventricular Tachycardia Ablation Center Collaborative Study. Vaseghi M, Hu TY, Tung R, Vergara P, Frankel DS, Di Biase L, Tedrow UB, Gornbein JA, Yu R, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Burkhardt JD, Tholakanahalli VN, Dickfeld TM, Weiss JP, Bunch TJ, Reddy M, Callans DJ, Lakkireddy DR, Natale A, Marchlinski FE, Stevenson WG, Della Bella P, Shivkumar K JACC. Clinical electrophysiology 30236386 JACC Clin Electrophysiol 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30236386
Sex and Race/Ethnicity Differences in Atrial Fibrillation. Volgman AS, Bairey Merz CN, Benjamin EJ, Curtis AB, Fang MC, Lindley KJ, Pepine CJ, Vaseghi M, Waldo AL, Wenger NK, Russo AM Journal of the American College of Cardiology 31779796 J Am Coll Cardiol 2019 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/31779796
The autonomic nervous system and ventricular arrhythmias in myocardial infarction and heart failure. Wu P, Vaseghi M Pacing and clinical electrophysiology : PACE 31823401 Pacing Clin Electrophysiol 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31823401
European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on risk assessment in cardiac arrhythmias: use the right tool for the right outcome, in the right population. Nielsen JC, Lin YJ, de Oliveira Figueiredo MJ, Sepehri Shamloo A, Alfie A, Boveda S, Dagres N, Di Toro D, Eckhardt LL, Ellenbogen K, Hardy C, Ikeda T, Jaswal A, Kaufman E, Krahn A, Kusano K, Kutyifa V, Lim HS, Lip GYH, Nava-Townsend S, Pak HN, Rodríguez Diez G, Sauer W, Saxena A, Svendsen JH, Vanegas D, Vaseghi M, Wilde A, Bunch TJ, ESC Scientific Document Group, Buxton AE, Calvimontes G, Chao TF, Eckardt L, Estner H, Gillis AM, Isa R, Kautzner J, Maury P, Moss JD, Nam GB, Olshansky B, Pava Molano LF, Pimentel M, Prabhu M, Tzou WS, Sommer P, Swampillai J, Vidal A, Deneke T, Hindricks G, Leclercq C Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 32538434 Europace 2020 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/32538434
Update on prevention and treatment of sudden cardiac arrest. Krokhaleva Y, Vaseghi M Trends in cardiovascular medicine 30449537 Trends Cardiovasc Med 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/30449537
Risk Stratification and Sudden Cardiac Death: Is It Time to Include Autonomic Variables? Khakpour H, Vaseghi M Circulation. Cardiovascular imaging 28794140 Circ Cardiovasc Imaging 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28794140
Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics. Shivkumar K, Ajijola OA, Anand I, Armour JA, Chen PS, Esler M, De Ferrari GM, Fishbein MC, Goldberger JJ, Harper RM, Joyner MJ, Khalsa SS, Kumar R, Lane R, Mahajan A, Po S, Schwartz PJ, Somers VK, Valderrabano M, Vaseghi M, Zipes DP The Journal of physiology 27114333 J Physiol 2016 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/27114333
Parasympathetic dysfunction and antiarrhythmic effect of vagal nerve stimulation following myocardial infarction. Vaseghi M, Salavatian S, Rajendran PS, Yagishita D, Woodward WR, Hamon D, Yamakawa K, Irie T, Habecker BA, Shivkumar K JCI insight 28814663 JCI Insight 2017 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/28814663
Thoracic Epidural Anesthesia Can Be Effective for the Short-Term Management of Ventricular Tachycardia Storm. Do DH, Bradfield J, Ajijola OA, Vaseghi M, Le J, Rahman S, Mahajan A, Nogami A, Boyle NG, Shivkumar K Journal of the American Heart Association 29079570 J Am Heart Assoc 2017 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/29079570
Antiarrhythmic effects of vagal nerve stimulation after cardiac sympathetic denervation in the setting of chronic myocardial infarction. Yamaguchi N, Yamakawa K, Rajendran PS, Takamiya T, Vaseghi M Heart rhythm 29530832 Heart Rhythm 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29530832
Premature ventricular contractions activate vagal afferents and alter autonomic tone: implications for premature ventricular contraction-induced cardiomyopathy. Salavatian S, Yamaguchi N, Hoang J, Lin N, Patel S, Ardell JL, Armour JA, Vaseghi M American journal of physiology. Heart and circulatory physiology 31322427 Am J Physiol Heart Circ Physiol 2019 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31322427
Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y. Hoang JD, Salavatian S, Yamaguchi N, Swid MA, David H, Vaseghi M JCI insight 32493842 JCI Insight 2020 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/32493842
Arrhythmic Risk Profile and Outcomes of Patients Undergoing Cardiac Sympathetic Denervation for Recurrent Monomorphic Ventricular Tachycardia After Ablation. Dusi V, Gornbein J, Do DH, Sorg JM, Khakpour H, Krokhaleva Y, Ajijola OA, Macias C, Bradfield JS, Buch E, Fujimura OA, Boyle NG, Yanagawa J, Lee JM, Shivkumar K, Vaseghi M Journal of the American Heart Association 33441022 J Am Heart Assoc 2021 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/33441022
A novel mechanism for regulation of cardiac Ca(2+) current by estradiol: cAMP-ing out at the basal epicardium. Hoang JD, Vaseghi M Heart rhythm 29382545 Heart Rhythm 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29382545
Cardiac neuroanatomy - Imaging nerves to define functional control. Hanna P, Rajendran PS, Ajijola OA, Vaseghi M, Andrew Armour J, Ardell JL, Shivkumar K Autonomic neuroscience : basic & clinical 28802636 Auton Neurosci 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28802636
Cardiac Innervation and the Autonomic Nervous System in Sudden Cardiac Death. Huang WA, Boyle NG, Vaseghi M Cardiac electrophysiology clinics 29173409 Card Electrophysiol Clin 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/29173409
No sympathy for the hypoxic: the role of fetal oxygenation in autonomic dysfunction. Hoang JD, Vaseghi M The Journal of physiology 29774552 J Physiol 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/29774552
Liver Disease as a Predictor of New-Onset Atrial Fibrillation. Huang WA, Dunipace EA, Sorg JM, Vaseghi M Journal of the American Heart Association 30371253 J Am Heart Assoc 2018 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/30371253
Ventricular Tachycardia in Dilated Cardiomyopathy: Is it Time for Genetic Testing in All Patients? Nguyen HL, Vaseghi M JACC. Clinical electrophysiology 32972545 JACC Clin Electrophysiol 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32972545
Relationship between sinus rhythm late activation zones and critical sites for scar-related ventricular tachycardia: systematic analysis of isochronal late activation mapping. Irie T, Yu R, Bradfield JS, Vaseghi M, Buch EF, Ajijola O, Macias C, Fujimura O, Mandapati R, Boyle NG, Shivkumar K, Tung R Circulation. Arrhythmia and electrophysiology 25740836 Circ Arrhythm Electrophysiol 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25740836
Arrhythmogenic Right Ventricular Cardiomyopathy: Electroarchitecture of the Substrate. Watanabe A, Seki A, Fishbein MC, Shivkumar K, Vaseghi M HeartRhythm case reports 26955520 HeartRhythm Case Rep 2016 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/26955520
Recurrent ventricular tachycardia after cardiac sympathetic denervation: Prolonged cycle length with improved hemodynamic tolerance and ablation outcomes. Hayase J, Dusi V, Do D, Ajijola OA, Vaseghi M, Lee JM, Yanagawa J, Hoftman N, Revels S, Buch EF, Khakpour H, Fujimura O, Krokhaleva Y, Macias C, Sorg J, Gima J, Pavez G, Boyle NG, Shivkumar K, Bradfield JS Journal of cardiovascular electrophysiology 32558054 J Cardiovasc Electrophysiol 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32558054
Looking Beyond Storm: Forecast Remains Gloomy for Clustered Ventricular Arrhythmias. Khakpour H, Vaseghi M JACC. Clinical electrophysiology 32192685 JACC Clin Electrophysiol 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/32192685
Myocardial infarction reduces cardiac nociceptive neurotransmission through the vagal ganglia. Salavatian S, Hoang JD, Yamaguchi N, Lokhandwala ZA, Swid MA, Armour JA, Ardell JL, Vaseghi M JCI insight 35015733 JCI Insight 2022 Feb 22 https://www.ncbi.nlm.nih.gov/pubmed/35015733
Phase-noise analysis of swept-source optical coherence tomography systems. Ling Y, Gan Y, Yao X, Hendon CP Optics letters 28362762 Opt Lett 2017 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/28362762
Comparative study of texture features in OCT images at different scales for human breast tissue classification. Yu Gan, Xinwen Yao, Chang E, Bin Amir S, Hibshoosh H, Feldman S, Hendon CP Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 28269144 Annu Int Conf IEEE Eng Med Biol Soc 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/28269144
An automated 3D registration method for optical coherence tomography volumes. Gan Y, Yao W, Myers KM, Hendon CP Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 25570837 Annu Int Conf IEEE Eng Med Biol Soc 2014 https://www.ncbi.nlm.nih.gov/pubmed/25570837
Analyzing three-dimensional ultrastructure of human cervical tissue using optical coherence tomography. Gan Y, Yao W, Myers KM, Vink JY, Wapner RJ, Hendon CP Biomedical optics express 25908997 Biomed Opt Express 2015 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/25908997
Near-infrared spectroscopy integrated catheter for characterization of myocardial tissues: preliminary demonstrations to radiofrequency ablation therapy for atrial fibrillation. Singh-Moon RP, Marboe CC, Hendon CP Biomedical optics express 26203376 Biomed Opt Express 2015 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/26203376
Compressed sensing of human breast optical coherence 3-D image volume data using predictive coding. Song Cho DM, Jerome MJ, Hendon CP Biomedical optics express 38021138 Biomed Opt Express 2023 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/38021138
Visualization and tissue classification of human breast cancer images using ultrahigh-resolution OCT. Yao X, Gan Y, Chang E, Hibshoosh H, Feldman S, Hendon C Lasers in surgery and medicine 28264146 Lasers Surg Med 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28264146
Multicontrast endomyocardial imaging by single-channel high-resolution cross-polarization optical coherence tomography. Yao X, Gan Y, Ling Y, Marboe CC, Hendon CP Journal of biophotonics 29165902 J Biophotonics 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29165902
Millimeter-scale chip-based supercontinuum generation for optical coherence tomography. Ji X, Mojahed D, Okawachi Y, Gaeta AL, Hendon CP, Lipson M Science advances 34533990 Sci Adv 2021 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/34533990
Optical coherence tomography-enabled classification of the human venoatrial junction. Joasil AS, Therien AM, Hendon CP Journal of biomedical optics 39840147 J Biomed Opt 2025 Jan https://www.ncbi.nlm.nih.gov/pubmed/39840147
Myocardial imaging using ultrahigh-resolution spectral domain optical coherence tomography. Yao X, Gan Y, Marboe CC, Hendon CP Journal of biomedical optics 27001162 J Biomed Opt 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27001162
Frequency-constrained robust principal component analysis: a sparse representation approach to segmentation of dynamic features in optical coherence tomography imaging. McLean JP, Ling Y, Hendon CP Optics express 29041245 Opt Express 2017 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/29041245
Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector. Ling Y, Yao X, Hendon CP Biomedical optics express 29082103 Biomed Opt Express 2017 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/29082103
Feasibility of near-infrared spectroscopy as a tool for anatomical mapping of the human epicardium. Singh-Moon RP, Park SY, Song Cho DM, Vaidya A, Marboe CC, Wan EY, Hendon CP Biomedical optics express 32923031 Biomed Opt Express 2020 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/32923031
Chip-based frequency comb sources for optical coherence tomography. Ji X, Yao X, Klenner A, Gan Y, Gaeta AL, Hendon CP, Lipson M Optics express 31503744 Opt Express 2019 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/31503744
Monitoring of irrigated lesion formation with single fiber based multispectral system using machine learning. Park SY, Singh-Moon RP, Yang H, Hendon CP Journal of biophotonics 35666015 J Biophotonics 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35666015
Heterogeneity Measurement of Cardiac Tissues Leveraging Uncertainty Information from Image Segmentation. Huang Z, Gan Y, Lye T, Zhang H, Laine A, Angelini ED, Hendon C Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 34169298 Med Image Comput Comput Assist Interv 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/34169298
A continuous fiber distribution material model for human cervical tissue. Myers KM, Hendon CP, Gan Y, Yao W, Yoshida K, Fernandez M, Vink J, Wapner RJ Journal of biomechanics 25817474 J Biomech 2015 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/25817474
Real-time optical spectroscopic monitoring of nonirrigated lesion progression within atrial and ventricular tissues. Singh-Moon RP, Yao X, Iyer V, Marboe C, Whang W, Hendon CP Journal of biophotonics 30058239 J Biophotonics 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30058239
3-D compressed sensing optical coherence tomography using predictive coding. McLean JP, Hendon CP Biomedical optics express 33996246 Biomed Opt Express 2021 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/33996246
Three-dimensional collagen fiber mapping and tractography of human uterine tissue using OCT. McLean JP, Fang S, Gallos G, Myers KM, Hendon CP Biomedical optics express 33149968 Biomed Opt Express 2020 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/33149968
Ex vivo visualization of human ciliated epithelium and quantitative analysis of induced flow dynamics by using optical coherence tomography. Ling Y, Yao X, Gamm UA, Arteaga-Solis E, Emala CW, Choma MA, Hendon CP Lasers in surgery and medicine 28231402 Lasers Surg Med 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28231402
Tissue-Specific Optical Mapping Models of Swine Atria Informed by Optical Coherence Tomography. Lye TH, Vincent KP, McCulloch AD, Hendon CP Biophysical journal 29590604 Biophys J 2018 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/29590604
Compressed sensing-enabled phase-sensitive swept-source optical coherence tomography. Ling Y, Meiniel W, Singh-Moon R, Angelini E, Olivo-Marin JC, Hendon CP Optics express 30696165 Opt Express 2019 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/30696165
Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women. Yao W, Gan Y, Myers KM, Vink JY, Wapner RJ, Hendon CP PloS one 27898677 PLoS One 2016 https://www.ncbi.nlm.nih.gov/pubmed/27898677
Automated classification of optical coherence tomography images of human atrial tissue. Gan Y, Tsay D, Amir SB, Marboe CC, Hendon CP Journal of biomedical optics 26926869 J Biomed Opt 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/26926869
Mapping the human pulmonary venoatrial junction with optical coherence tomography. Lye TH, Iyer V, Marboe CC, Hendon CP Biomedical optics express 30800491 Biomed Opt Express 2019 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/30800491
Fully Automated Postlumpectomy Breast Margin Assessment Utilizing Convolutional Neural Network Based Optical Coherence Tomography Image Classification Method. Mojahed D, Ha RS, Chang P, Gan Y, Yao X, Angelini B, Hibshoosh H, Taback B, Hendon CP Academic radiology 31324579 Acad Radiol 2020 May https://www.ncbi.nlm.nih.gov/pubmed/31324579
Characterization of the human myocardium by optical coherence tomography. Gan Y, Lye TH, Marboe CC, Hendon CP Journal of biophotonics 31400074 J Biophotonics 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31400074
Imaging of subendocardial adipose tissue and fiber orientation distributions in the human left atrium using optical coherence tomography. Lye TH, Marboe CC, Hendon CP Journal of cardiovascular electrophysiology 31661178 J Cardiovasc Electrophysiol 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31661178
Optical coherence tomography imaging of cardiac substrates. Hendon CP, Lye TH, Yao X, Gan Y, Marboe CC Quantitative imaging in medicine and surgery 31281782 Quant Imaging Med Surg 2019 May https://www.ncbi.nlm.nih.gov/pubmed/31281782
Optical coherence tomography holds promise to transform the diagnostic anatomic pathology gross evaluation process. Mojahed D, Applegate M, Guo H, Taback B, Ha R, Hibshoosh H, Hendon C Journal of biomedical optics 36050827 J Biomed Opt 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/36050827
Cardiac endocardial left atrial substrate and lesion depth mapping using near-infrared spectroscopy. Park SY, Yang H, Marboe C, Ziv O, Laurita K, Rollins A, Saluja D, Hendon CP Biomedical optics express 35519253 Biomed Opt Express 2022 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/35519253
Quantification of irrigated lesion morphology using near-infrared spectroscopy. Park SY, Singh-Moon R, Yang H, Saluja D, Hendon C Scientific reports 34635764 Sci Rep 2021 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/34635764
Cardiac Adipose Tissue Segmentation via Image-Level Annotations. Huang Z, Gan Y, Lye T, Liu Y, Zhang H, Laine A, Angelini E, Hendon C IEEE journal of biomedical and health informatics 37023157 IEEE J Biomed Health Inform 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/37023157
Cardiac Light-Sheet Fluorescent Microscopy for Multi-Scale and Rapid Imaging of Architecture and Function. Fei P, Lee J, Packard RR, Sereti KI, Xu H, Ma J, Ding Y, Kang H, Chen H, Sung K, Kulkarni R, Ardehali R, Kuo CC, Xu X, Ho CM, Hsiai TK Scientific reports 26935567 Sci Rep 2016 Mar 3 https://www.ncbi.nlm.nih.gov/pubmed/26935567
Harnessing the versatility of PLGA nanoparticles for targeted Cre-mediated recombination. Nguyen NB, Chen CH, Zhang Y, Zhao P, Wu BM, Ardehali R Nanomedicine : nanotechnology, biology, and medicine 31026512 Nanomedicine 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31026512
Translational aspects of cardiac cell therapy. Chen CH, Sereti KI, Wu BM, Ardehali R Journal of cellular and molecular medicine 26119413 J Cell Mol Med 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26119413
Sendai virus based direct cardiac reprogramming: what lies ahead? Engel JL, Ardehali R Stem cell investigation 30498748 Stem Cell Investig 2018 https://www.ncbi.nlm.nih.gov/pubmed/30498748
Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, Mikkola HKA, Iruela-Arispe ML, Ardehali R Nature communications 29467410 Nat Commun 2018 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/29467410
In Vivo Clonal Analysis of Cardiomyocytes. Nguyen NB, Fernandez GE, Ding Y, Hsiai T, Ardehali R Methods in molecular biology (Clifton, N.J.) 32857378 Methods Mol Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/32857378
Direct Cardiac Reprogramming: Progress and Promise. Engel JL, Ardehali R Stem cells international 29731772 Stem Cells Int 2018 https://www.ncbi.nlm.nih.gov/pubmed/29731772
Cardiac fibrosis: potential therapeutic targets. Park S, Nguyen NB, Pezhouman A, Ardehali R Translational research : the journal of laboratory and clinical medicine 30930180 Transl Res 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/30930180
Direct cardiac reprogramming: A new frontier in heart regeneration. Ardehali R Seminars in cell & developmental biology 34538519 Semin Cell Dev Biol 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/34538519
Environmental factors influence somatic cell reprogramming to cardiomyocyte-like cells. Van Handel B, Wang L, Ardehali R Seminars in cell & developmental biology 34083115 Semin Cell Dev Biol 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/34083115
Cardiac Fibrosis Is Associated With Decreased Circulating Levels of Full-Length CILP in Heart Failure. Park S, Ranjbarvaziri S, Zhao P, Ardehali R JACC. Basic to translational science 32478206 JACC Basic Transl Sci 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32478206
Heart Regeneration by Endogenous Stem Cells and Cardiomyocyte Proliferation: Controversy, Fallacy, and Progress. He L, Nguyen NB, Ardehali R, Zhou B Circulation 32687441 Circulation 2020 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/32687441
Biomarkers of Human Pluripotent Stem Cell-Derived Cardiac Lineages. Skelton RJP, Kamp TJ, Elliott DA, Ardehali R Trends in molecular medicine 28576602 Trends Mol Med 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28576602
Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. Park S, Ranjbarvaziri S, Lay FD, Zhao P, Miller MJ, Dhaliwal JS, Huertas-Vazquez A, Wu X, Qiao R, Soffer JM, Rau C, Wang Y, Mikkola HKA, Lusis AJ, Ardehali R Circulation 29950403 Circulation 2018 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/29950403
Generation of Nkx2-5/CreER transgenic mice for inducible Cre expression in developing hearts. Ranjbarvaziri S, Park S, Nguyen NB, Gilmore WB, Zhao P, Ardehali R Genesis (New York, N.Y. : 2000) 28589709 Genesis 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28589709
Arrhythmia in stem cell transplantation. Almeida SO, Skelton RJ, Adigopula S, Ardehali R Cardiac electrophysiology clinics 26002399 Card Electrophysiol Clin 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/26002399
HBL1 Is a Human Long Noncoding RNA that Modulates Cardiomyocyte Development from Pluripotent Stem Cells by Counteracting MIR1. Liu J, Li Y, Lin B, Sheng Y, Yang L Developmental cell 28829943 Dev Cell 2017 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/28829943
HBL1 Is a Human Long Noncoding RNA that Modulates Cardiomyocyte Development from Pluripotent Stem Cells by Counteracting MIR1. Liu J, Li Y, Lin B, Sheng Y, Yang L Developmental cell 29112854 Dev Cell 2017 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/29112854
Mechanism of automaticity in cardiomyocytes derived from human induced pluripotent stem cells. Kim JJ, Yang L, Lin B, Zhu X, Sun B, Kaplan AD, Bett GC, Rasmusson RL, London B, Salama G Journal of molecular and cellular cardiology 25644533 J Mol Cell Cardiol 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25644533
Genome-wide studies reveal the essential and opposite roles of ARID1A in controlling human cardiogenesis and neurogenesis from pluripotent stem cells. Liu J, Liu S, Gao H, Han L, Chu X, Sheng Y, Shou W, Wang Y, Liu Y, Wan J, Yang L Genome biology 32646524 Genome Biol 2020 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/32646524
Comparative transcriptomic analysis of multiple cardiovascular fates from embryonic stem cells predicts novel regulators in human cardiogenesis. Li Y, Lin B, Yang L Scientific reports 25997157 Sci Rep 2015 May 21 https://www.ncbi.nlm.nih.gov/pubmed/25997157
Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy. Lin B, Li Y, Han L, Kaplan AD, Ao Y, Kalra S, Bett GC, Rasmusson RL, Denning C, Yang L Disease models & mechanisms 25791035 Dis Model Mech 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25791035
Multiscale reverse engineering of the human ocular surface. Seo J, Byun WY, Alisafaei F, Georgescu A, Yi YS, Massaro-Giordano M, Shenoy VB, Lee V, Bunya VY, Huh D Nature medicine 31384041 Nat Med 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31384041
Microphysiological Engineering of Self-Assembled and Perfusable Microvascular Beds for the Production of Vascularized Three-Dimensional Human Microtissues. Paek J, Park SE, Lu Q, Park KT, Cho M, Oh JM, Kwon KW, Yi YS, Song JW, Edelstein HI, Ishibashi J, Yang W, Myerson JW, Kiseleva RY, Aprelev P, Hood ED, Stambolian D, Seale P, Muzykantov VR, Huh D ACS nano 31194909 ACS Nano 2019 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/31194909
Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue. Mondrinos MJ, Alisafaei F, Yi AY, Ahmadzadeh H, Lee I, Blundell C, Seo J, Osborn M, Jeon TJ, Kim SM, Shenoy VB, Huh D Science advances 33712463 Sci Adv 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33712463
In Vitro Granuloma Models of Tuberculosis: Potential and Challenges. Elkington P, Lerm M, Kapoor N, Mahon R, Pienaar E, Huh D, Kaushal D, Schlesinger LS The Journal of infectious diseases 30929010 J Infect Dis 2019 May 24 https://www.ncbi.nlm.nih.gov/pubmed/30929010
Placenta-on-a-chip: a novel platform to study the biology of the human placenta. Lee JS, Romero R, Han YM, Kim HC, Kim CJ, Hong JS, Huh D The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 26075842 J Matern Fetal Neonatal Med 2016 https://www.ncbi.nlm.nih.gov/pubmed/26075842
A microphysiological model of the human placental barrier. Blundell C, Tess ER, Schanzer AS, Coutifaris C, Su EJ, Parry S, Huh D Lab on a chip 27229450 Lab Chip 2016 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/27229450
Soft robotic constrictor for in vitro modeling of dynamic tissue compression. Paek J, Song JW, Ban E, Morimitsu Y, Osuji CO, Shenoy VB, Huh DD Scientific reports 34389738 Sci Rep 2021 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/34389738
Polydopamine-Based Interfacial Engineering of Extracellular Matrix Hydrogels for the Construction and Long-Term Maintenance of Living Three-Dimensional Tissues. Park SE, Georgescu A, Oh JM, Kwon KW, Huh D ACS applied materials & interfaces 31199616 ACS Appl Mater Interfaces 2019 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/31199616
Self-organization of the hematopoietic vascular niche and emergent innate immunity on a chip. Georgescu A, Oved JH, Galarraga JH, Cantrell T, Mehta S, Dulmovits BM, Olson TS, Fattahi P, Wang A, Candarlioglu PL, Muvaffak A, Kim MM, Aydin SA, Seo J, Diffenderfer ES, Lynch A, Worthen GS, Huh DD Cell stem cell 39642865 Cell Stem Cell 2024 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/39642865
Native extracellular matrix-derived semipermeable, optically transparent, and inexpensive membrane inserts for microfluidic cell culture. Mondrinos MJ, Yi YS, Wu NK, Ding X, Huh D Lab on a chip 28809418 Lab Chip 2017 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/28809418
A Human Vascular Injury-on-a-Chip Model of Hemostasis. Poventud-Fuentes I, Kwon KW, Seo J, Tomaiuolo M, Stalker TJ, Brass LF, Huh D Small (Weinheim an der Bergstrasse, Germany) 33150735 Small 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33150735
Organoids-on-a-chip. Park SE, Georgescu A, Huh D Science (New York, N.Y.) 31171693 Science 2019 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/31171693
A bioinspired microfluidic model of liquid plug-induced mechanical airway injury. Song JW, Paek J, Park KT, Seo J, Huh D Biomicrofluidics 29887935 Biomicrofluidics 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29887935
Placental Drug Transport-on-a-Chip: A Microengineered In Vitro Model of Transporter-Mediated Drug Efflux in the Human Placental Barrier. Blundell C, Yi YS, Ma L, Tess ER, Farrell MJ, Georgescu A, Aleksunes LM, Huh D Advanced healthcare materials 29121458 Adv Healthc Mater 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29121458
A microengineered pathophysiological model of early-stage breast cancer. Choi Y, Hyun E, Seo J, Blundell C, Kim HC, Lee E, Lee SH, Moon A, Moon WK, Huh D Lab on a chip 26158500 Lab Chip 2015 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/26158500
Geometric engineering of organoid culture for enhanced organogenesis in a dish. Park SE, Kang S, Paek J, Georgescu A, Chang J, Yi AY, Wilkins BJ, Karakasheva TA, Hamilton KE, Huh DD Nature methods 36280722 Nat Methods 2022 Nov https://www.ncbi.nlm.nih.gov/pubmed/36280722
Bacterial Pneumonia in Patients with Cancer: Novel Risk Factors and Management. Wong JL, Evans SE Clinics in chest medicine 28477638 Clin Chest Med 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28477638
Progression of the Radiologic Severity Index predicts mortality in patients with parainfluenza virus-associated lower respiratory infections. Sheshadri A, Shah DP, Godoy M, Erasmus JJ, Song J, Li L, Evans SE, Chemaly RF, Dickey BF, Ost DE PloS one 29771962 PLoS One 2018 https://www.ncbi.nlm.nih.gov/pubmed/29771962
Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense. Leiva-Juárez MM, Kolls JK, Evans SE Mucosal immunology 28812547 Mucosal Immunol 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/28812547
Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir. Leiva-Juarez MM, Kirkpatrick CT, Gilbert BE, Scott B, Tuvim MJ, Dickey BF, Evans SE, Markesich D European journal of pharmacology 29066417 Eur J Pharmacol 2018 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/29066417
Editorial: Purinergic Signaling and Inflammation. Yuan X, Ferrari D, Mills T, Wang Y, Czopik A, Doursout MF, Evans SE, Idzko M, Eltzschig HK Frontiers in immunology 34093597 Front Immunol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34093597
OBIF: an omics-based interaction framework to reveal molecular drivers of synergy. Pantaleón García J, Kulkarni VV, Reese TC, Wali S, Wase SJ, Zhang J, Singh R, Caetano MS, Kadara H, Moghaddam SJ, Johnson FM, Wang J, Wang Y, Evans SE NAR genomics and bioinformatics 35387383 NAR Genom Bioinform 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35387383
Muc5b is required for airway defence. Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM Nature 24317696 Nature 2014 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/24317696
The development and plasticity of alveolar type 1 cells. Yang J, Hernandez BJ, Martinez Alanis D, Narvaez del Pilar O, Vila-Ellis L, Akiyama H, Evans SE, Ostrin EJ, Chen J Development (Cambridge, England) 26586225 Development 2016 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/26586225
Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice. Goldblatt DL, Flores JR, Valverde Ha G, Jaramillo AM, Tkachman S, Kirkpatrick CT, Wali S, Hernandez B, Ost DE, Scott BL, Chen J, Evans SE, Tuvim MJ, Dickey BF British journal of pharmacology 31968123 Br J Pharmacol 2020 May https://www.ncbi.nlm.nih.gov/pubmed/31968123
Targeting the Hypoxia-Adenosine Link for Controlling Excessive Inflammation. Czopik A, Yuan X, Evans SE, Eltzschig HK Anesthesiology 34046661 Anesthesiology 2021 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/34046661
Selective Modulation of the Pulmonary Innate Immune Response Does Not Change Lung Microbiota in Healthy Mice. Pantaleón García J, Hinkle KJ, Falkowski NR, Evans SE, Dickson RP American journal of respiratory and critical care medicine 34153197 Am J Respir Crit Care Med 2021 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/34153197
Pneumonia in the neutropenic cancer patient. Evans SE, Ost DE Current opinion in pulmonary medicine 25784246 Curr Opin Pulm Med 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25784246
MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis. Abe JI, Ko KA, Kotla S, Wang Y, Paez-Mayorga J, Shin IJ, Imanishi M, Vu HT, Tao Y, Leiva-Juarez MM, Thomas TN, Medina JL, Won JH, Fujii Y, Giancursio CJ, McBeath E, Shin JH, Guzman L, Abe RJ, Taunton J, Mochizuki N, Faubion W, Cooke JP, Fujiwara K, Evans SE, Le NT JCI insight 30944250 JCI Insight 2019 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/30944250
Future Research Directions in Pneumonia. NHLBI Working Group Report. Dela Cruz CS, Wunderink RG, Christiani DC, Cormier SA, Crothers K, Doerschuk CM, Evans SE, Goldstein DR, Khatri P, Kobzik L, Kolls JK, Levy BD, Metersky ML, Niederman MS, Nusrat R, Orihuela CJ, Peyrani P, Prince AS, Ramírez JA, Ridge KM, Sethi S, Suratt BT, Sznajder JI, Tsalik EL, Walkey AJ, Yende S, Aggarwal NR, Caler EV, Mizgerd JP American journal of respiratory and critical care medicine 29546996 Am J Respir Crit Care Med 2018 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/29546996
Minimizing caging effects in murine lung microbiome studies. Pantaleón García J, Dickson RP, Evans SE American journal of physiology. Lung cellular and molecular physiology 35944140 Am J Physiol Lung Cell Mol Physiol 2022 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/35944140
Epithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice. Goldblatt DL, Valverde Ha G, Wali S, Kulkarni VV, Longmire MK, Jaramillo AM, Chittuluru RP, Fouts A, Martinez-Moczygemba M, Lei JT, Huston DP, Tuvim MJ, Dickey BF, Evans SE Frontiers in pharmacology 36105216 Front Pharmacol 2022 https://www.ncbi.nlm.nih.gov/pubmed/36105216
Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial immunometabolic modulation. Wang Y, Kulkarni VV, Pantaleón García J, Leiva-Juárez MM, Goldblatt DL, Gulraiz F, Vila Ellis L, Chen J, Longmire MK, Donepudi SR, Lorenzi PL, Wang H, Wong LJ, Tuvim MJ, Evans SE PLoS pathogens 37695784 PLoS Pathog 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37695784
Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands. Alfaro VY, Goldblatt DL, Valverde GR, Munsell MF, Quinton LJ, Walker AK, Dantzer R, Varadhachary A, Scott BL, Evans SE, Tuvim MJ, Dickey BF Frontiers in pharmacology 24567720 Front Pharmacol 2014 https://www.ncbi.nlm.nih.gov/pubmed/24567720
Fungal Pneumonia in Patients with Hematologic Malignancy and Hematopoietic Stem Cell Transplantation. Young AY, Leiva Juarez MM, Evans SE Clinics in chest medicine 28797490 Clin Chest Med 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/28797490
Inducible epithelial resistance protects mice against leukemia-associated pneumonia. Leiva-Juárez MM, Ware HH, Kulkarni VV, Zweidler-McKay PA, Tuvim MJ, Evans SE Blood 27317793 Blood 2016 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/27317793
Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial metabolic reprogramming. Wang Y, Kulkarni VV, Pantaleón García J, Leiva-Juárez MM, Goldblatt DL, Gulraiz F, Chen J, Donepudi SR, Lorenzi PL, Wang H, Wong LJ, Tuvim MJ, Evans SE bioRxiv : the preprint server for biology 36711510 bioRxiv 2023 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/36711510
Redox-Dependent Activation of Lung Epithelial STAT3 Is Required for Inducible Protection against Bacterial Pneumonia. Kulkarni VV, Wang Y, Pantaleon Garcia J, Evans SE American journal of respiratory cell and molecular biology 36826841 Am J Respir Cell Mol Biol 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/36826841
Toll-like receptor-2/6 and Toll-like receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs. Drake MG, Evans SE, Dickey BF, Fryer AD, Jacoby DB American journal of respiratory cell and molecular biology 23449736 Am J Respir Cell Mol Biol 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23449736
Lung epithelial cells are essential effectors of inducible resistance to pneumonia. Cleaver JO, You D, Michaud DR, Pruneda FA, Juarez MM, Zhang J, Weill PM, Adachi R, Gong L, Moghaddam SJ, Poynter ME, Tuvim MJ, Evans SE Mucosal immunology 23632328 Mucosal Immunol 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/23632328
Porous silicon microparticle potentiates anti-tumor immunity by enhancing cross-presentation and inducing type I interferon response. Xia X, Mai J, Xu R, Perez JET, Guevara ML, Shen Q, Mu C, Tung HY, Corry DB, Evans SE, Liu X, Ferrari M, Zhang Z, Li XC, Wang RF, Shen H Cell reports 25937283 Cell Rep 2015 May 12 https://www.ncbi.nlm.nih.gov/pubmed/25937283
Viral Pneumonia in Patients with Hematologic Malignancy or Hematopoietic Stem Cell Transplantation. Vakil E, Evans SE Clinics in chest medicine 28159165 Clin Chest Med 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28159165
A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo. Covés-Datson EM, King SR, Legendre M, Gupta A, Chan SM, Gitlin E, Kulkarni VV, Pantaleón García J, Smee DF, Lipka E, Evans SE, Tarbet EB, Ono A, Markovitz DM Proceedings of the National Academy of Sciences of the United States of America 31932446 Proc Natl Acad Sci U S A 2020 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/31932446
Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections. Kirkpatrick CT, Wang Y, Leiva Juarez MM, Shivshankar P, Pantaleón García J, Plumer AK, Kulkarni VV, Ware HH, Gulraiz F, Chavez Cavasos MA, Martinez Zayas G, Wali S, Rice AP, Liu H, Tour JM, Sikkema WKA, Cruz Solbes AS, Youker KA, Tuvim MJ, Dickey BF, Evans SE mBio 29764948 mBio 2018 May 15 https://www.ncbi.nlm.nih.gov/pubmed/29764948
Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against bacterial infections. Ware HH, Kulkarni VV, Wang Y, Pantaleón García J, Leiva Juarez M, Kirkpatrick CT, Wali S, Syed S, Kontoyiannis AD, Sikkema WKA, Tour JM, Evans SE PloS one 30794556 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/30794556
Immune Modulation to Improve Survival of Viral Pneumonia in Mice. Wali S, Flores JR, Jaramillo AM, Goldblatt DL, Pantaleón García J, Tuvim MJ, Dickey BF, Evans SE American journal of respiratory cell and molecular biology 32853024 Am J Respir Cell Mol Biol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32853024
Repetitive aeroallergen challenges elucidate maladaptive epithelial and inflammatory traits that underpin allergic airway diseases. Smith AM, Harper N, Meunier JA, Branum AP, Jimenez F, Pandranki L, Carrillo A, Dela Cruz CS, Restrepo MI, Maselli DJ, Rather CG, Heisser AH, Ramirez DA, He W, Clark RA, Andrews CP, Evans SE, Pugh JA, Zhang N, Lee GC, Moreira AG, Segal LN, Ramirez RM, Jacobs RL, Manoharan MS, Okulicz JF, Ahuja SK The Journal of allergy and clinical immunology 33493557 J Allergy Clin Immunol 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/33493557
The RNA receptor RIG-I binding synthetic oligodeoxynucleotide promotes pneumonia survival. Wang Y, Kulkarni VV, PantaleónGarcía J, Longmire MK, Lethier M, Cusack S, Evans SE JCI insight 39352770 JCI Insight 2024 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/39352770
Alternative Splicing, Internal Promoter, Nonsense-Mediated Decay, or All Three: Explaining the Distribution of Truncation Variants in Titin. Deo RC Circulation. Cardiovascular genetics 27625338 Circ Cardiovasc Genet 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27625338
Response by Zhang and Deo to Letter Regarding Article, "Fully Automated Echocardiogram Interpretation in Clinical Practice: Feasibility and Diagnostic Accuracy". Zhang J, Deo RC Circulation 30908098 Circulation 2019 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/30908098
An International Multicenter Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2-Catecholaminergic Polymorphic Ventricular Tachycardia. Ng K, Titus EW, Lieve KV, Roston TM, Mazzanti A, Deiter FH, Denjoy I, Ingles J, Till J, Robyns T, Connors SP, Steinberg C, Abrams DJ, Pang B, Scheinman MM, Bos JM, Duffett SA, van der Werf C, Maltret A, Green MS, Rutberg J, Balaji S, Cadrin-Tourigny J, Orland KM, Knight LM, Brateng C, Wu J, Tang AS, Skanes AC, Manlucu J, Healey JS, January CT, Krahn AD, Collins KK, Maginot KR, Fischbach P, Etheridge SP, Eckhardt LL, Hamilton RM, Ackerman MJ, Noguer FRI, Semsarian C, Jura N, Leenhardt A, Gollob MH, Priori SG, Sanatani S, Wilde AAM, Deo RC, Roberts JD Circulation 32693635 Circulation 2020 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/32693635
Targeted deep sequencing reveals no definitive evidence for somatic mosaicism in atrial fibrillation. Roberts JD, Longoria J, Poon A, Gollob MH, Dewland TA, Kwok PY, Olgin JE, Deo RC, Marcus GM Circulation. Cardiovascular genetics 25406240 Circ Cardiovasc Genet 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25406240
Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary. Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB Circulation 32202936 Circulation 2020 Mar 24 https://www.ncbi.nlm.nih.gov/pubmed/32202936
The structure of a calsequestrin filament reveals mechanisms of familial arrhythmia. Titus EW, Deiter FH, Shi C, Wojciak J, Scheinman M, Jura N, Deo RC Nature structural & molecular biology 33046906 Nat Struct Mol Biol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33046906
Learning About Machine Learning: The Promise and Pitfalls of Big Data and the Electronic Health Record. Deo RC, Nallamothu BK Circulation. Cardiovascular quality and outcomes 28263936 Circ Cardiovasc Qual Outcomes 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/28263936
RNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells. Vedantham V, Galang G, Evangelista M, Deo RC, Srivastava D Circulation research 25623957 Circ Res 2015 Feb 27 https://www.ncbi.nlm.nih.gov/pubmed/25623957
Prioritizing causal disease genes using unbiased genomic features. Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok PY, MacRae CA, Roth FP Genome biology 25633252 Genome Biol 2014 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/25633252
Machine Learning in Medicine. Deo RC Circulation 26572668 Circulation 2015 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/26572668
An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish. Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC eLife 26473617 Elife 2015 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/26473617
Automated and Interpretable Patient ECG Profiles for Disease Detection, Tracking, and Discovery. Tison GH, Zhang J, Delling FN, Deo RC Circulation. Cardiovascular quality and outcomes 31525078 Circ Cardiovasc Qual Outcomes 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31525078
Precision Phenotyping of Dilated Cardiomyopathy Using Multidimensional Data. Tayal U, Verdonschot JAJ, Hazebroek MR, Howard J, Gregson J, Newsome S, Gulati A, Pua CJ, Halliday BP, Lota AS, Buchan RJ, Whiffin N, Kanapeckaite L, Baruah R, Jarman JWE, O'Regan DP, Barton PJR, Ware JS, Pennell DJ, Adriaans BP, Bekkers SCAM, Donovan J, Frenneaux M, Cooper LT, Januzzi JL Jr, Cleland JGF, Cook SA, Deo RC, Heymans SRB, Prasad SK Journal of the American College of Cardiology 35654493 J Am Coll Cardiol 2022 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/35654493
Phenomapping for novel classification of heart failure with preserved ejection fraction. Shah SJ, Katz DH, Selvaraj S, Burke MA, Yancy CW, Gheorghiade M, Bonow RO, Huang CC, Deo RC Circulation 25398313 Circulation 2015 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/25398313
Regulatory constraints in the generation and differentiation of IgE-expressing B cells. Yang Z, Robinson MJ, Allen CD Current opinion in immunology 24632082 Curr Opin Immunol 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24632082
Expression of Exogenous Genes in Murine Primary B Cells and B Cell Lines Using Retroviral Vectors. Yang Z, Allen CDC Methods in molecular biology (Clifton, N.J.) 29388098 Methods Mol Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/29388098
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Cryopreserved cell-laden alginate microgel bioink for 3D bioprinting of living tissues. Jeon O, Bin Lee Y, Hinton TJ, Feinberg AW, Alsberg E Materials today. Chemistry 30778400 Mater Today Chem 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/30778400
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Engineering Aligned Skeletal Muscle Tissue Using Decellularized Plant-Derived Scaffolds. Cheng YW, Shiwarski DJ, Ball RL, Whitehead KA, Feinberg AW ACS biomaterials science & engineering 33463300 ACS Biomater Sci Eng 2020 May 11 https://www.ncbi.nlm.nih.gov/pubmed/33463300
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Understanding the Role of ECM Protein Composition and Geometric Micropatterning for Engineering Human Skeletal Muscle. Duffy RM, Sun Y, Feinberg AW Annals of biomedical engineering 26983843 Ann Biomed Eng 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/26983843
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3D bioprinting of collagen to rebuild components of the human heart. Lee A, Hudson AR, Shiwarski DJ, Tashman JW, Hinton TJ, Yerneni S, Bliley JM, Campbell PG, Feinberg AW Science (New York, N.Y.) 31371612 Science 2019 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/31371612
Engineering aligned human cardiac muscle using developmentally inspired fibronectin micropatterns. Batalov I, Jallerat Q, Kim S, Bliley J, Feinberg AW Scientific reports 34075068 Sci Rep 2021 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/34075068
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Large volume syringe pump extruder for desktop 3D printers. Pusch K, Hinton TJ, Feinberg AW HardwareX 30498799 HardwareX 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/30498799
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Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype. Bliley JM, Vermeer MCSC, Duffy RM, Batalov I, Kramer D, Tashman JW, Shiwarski DJ, Lee A, Teplenin AS, Volkers L, Coffin B, Hoes MF, Kalmykov A, Palchesko RN, Sun Y, Jongbloed JDH, Bomer N, de Boer RA, Suurmeijer AJH, Pijnappels DA, Bolling MC, van der Meer P, Feinberg AW Science translational medicine 34290054 Sci Transl Med 2021 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/34290054
Engineering artificial cells by combining HeLa-based cell-free expression and ultrathin double emulsion template. Ho KK, Murray VL, Liu AP Methods in cell biology 25997354 Methods Cell Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25997354
Cell-sized mechanosensitive and biosensing compartment programmed with DNA. Majumder S, Garamella J, Wang YL, DeNies M, Noireaux V, Liu AP Chemical communications (Cambridge, England) 28524182 Chem Commun (Camb) 2017 Jun 29 https://www.ncbi.nlm.nih.gov/pubmed/28524182
Development of an advanced microfluidic micropipette aspiration device for single cell mechanics studies. Lee LM, Lee JW, Chase D, Gebrezgiabhier D, Liu AP Biomicrofluidics 27703591 Biomicrofluidics 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/27703591
Synergistic and non-specific nucleic acid production by T7 RNA polymerase and Bsu DNA polymerase catalyzed by single-stranded polynucleotides. Emery NJ, Majumder S, Liu AP Synthetic and systems biotechnology 29900426 Synth Syst Biotechnol 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29900426
Cofactoring and dimerization of proteinase-activated receptors. Lin H, Liu AP, Smith TH, Trejo J Pharmacological reviews 24064459 Pharmacol Rev 2013 https://www.ncbi.nlm.nih.gov/pubmed/24064459
The rise of bottom-up synthetic biology and cell-free biology. Liu AP Physical biology 31018188 Phys Biol 2019 May 7 https://www.ncbi.nlm.nih.gov/pubmed/31018188
Bottom-up synthetic biology: modular design for making artificial platelets. Majumder S, Liu AP Physical biology 29091050 Phys Biol 2017 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/29091050
Uniaxial cell stretching device for live-cell imaging of mechanosensitive cellular functions. Shao Y, Tan X, Novitski R, Muqaddam M, List P, Williamson L, Fu J, Liu AP The Review of scientific instruments 24289415 Rev Sci Instrum 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/24289415
Lipid bilayer vesicle generation using microfluidic jetting. Coyne CW, Patel K, Heureaux J, Stachowiak J, Fletcher DA, Liu AP Journal of visualized experiments : JoVE 24637415 J Vis Exp 2014 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/24637415
Advanced Microfluidic Device Designed for Cyclic Compression of Single Adherent Cells. Ho KKY, Wang YL, Wu J, Liu AP Frontiers in bioengineering and biotechnology 30386779 Front Bioeng Biotechnol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30386779
Biophysical Tools for Cellular and Subcellular Mechanical Actuation of Cell Signaling. Liu AP Biophysical journal 27456131 Biophys J 2016 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/27456131
Multiplex detection of homo- and heterodimerization of g protein-coupled receptors by proximity biotinylation. Steel E, Murray VL, Liu AP PloS one 24691126 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/24691126
Mechanically activated artificial cell by using microfluidics. Ho KK, Lee LM, Liu AP Scientific reports 27610921 Sci Rep 2016 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/27610921
Simultaneous monitoring of transcription and translation in mammalian cell-free expression in bulk and in cell-sized droplets. Wang S, Majumder S, Emery NJ, Liu AP Synthetic biology (Oxford, England) 30003145 Synth Biol (Oxf) 2018 https://www.ncbi.nlm.nih.gov/pubmed/30003145
Protein aggregation with poly(vinyl) alcohol surfactant reduces double emulsion-encapsulated mammalian cell-free expression. Ho KK, Lee JW, Durand G, Majumder S, Liu AP PloS one 28358875 PLoS One 2017 https://www.ncbi.nlm.nih.gov/pubmed/28358875
Cell-free compartmentalized protein synthesis inside double emulsion templated liposomes with in vitro synthesized and assembled ribosomes. Caschera F, Lee JW, Ho KK, Liu AP, Jewett MC Chemical communications (Cambridge, England) 27019994 Chem Commun (Camb) 2016 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/27019994
Activation of a bacterial mechanosensitive channel in mammalian cells by cytoskeletal stress. Heureaux J, Chen D, Murray VL, Deng CX, Liu AP Cellular and molecular bioengineering 25606062 Cell Mol Bioeng 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25606062
A microfluidic pipette array for mechanophenotyping of cancer cells and mechanical gating of mechanosensitive channels. Lee LM, Liu AP Lab on a chip 25361042 Lab Chip 2015 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/25361042
The Application of Micropipette Aspiration in Molecular Mechanics of Single Cells. Lee LM, Liu AP Journal of nanotechnology in engineering and medicine 26155329 J Nanotechnol Eng Med 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/26155329
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CF airway smooth muscle transcriptome reveals a role for PYK2. Cook DP, Adam RJ, Zarei K, Deonovic B, Stroik MR, Gansemer ND, Meyerholz DK, Au KF, Stoltz DA JCI insight 28878137 JCI Insight 2017 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/28878137
Air trapping and airflow obstruction in newborn cystic fibrosis piglets. Adam RJ, Michalski AS, Bauer C, Abou Alaiwa MH, Gross TJ, Awadalla MS, Bouzek DC, Gansemer ND, Taft PJ, Hoegger MJ, Diwakar A, Ochs M, Reinhardt JM, Hoffman EA, Beichel RR, Meyerholz DK, Stoltz DA American journal of respiratory and critical care medicine 24168209 Am J Respir Crit Care Med 2013 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/24168209
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Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs. Hoegger MJ, Awadalla M, Namati E, Itani OA, Fischer AJ, Tucker AJ, Adam RJ, McLennan G, Hoffman EA, Stoltz DA, Welsh MJ Proceedings of the National Academy of Sciences of the United States of America 24474805 Proc Natl Acad Sci U S A 2014 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/24474805
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A Panoramic View of Cell Population Dynamics in Mammalian Aging. Zhang Z, Schaefer C, Jiang W, Lu Z, Lee J, Sziraki A, Abdulraouf A, Wick B, Haeussler M, Li Z, Molla G, Satija R, Zhou W, Cao J bioRxiv : the preprint server for biology 38496474 bioRxiv 2024 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/38496474
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A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains. Sziraki A, Lu Z, Lee J, Banyai G, Anderson S, Abdulraouf A, Metzner E, Liao A, Banfelder J, Epstein A, Schaefer C, Xu Z, Zhang Z, Gan L, Nelson PT, Zhou W, Cao J Nature genetics 38036784 Nat Genet 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/38036784
Optics-free Spatial Genomics for Mapping Mouse Brain Aging. Abdulraouf A, Jiang W, Xu Z, Zhang Z, Isakov S, Raihan T, Zhou W, Cao J bioRxiv : the preprint server for biology 39149282 bioRxiv 2024 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/39149282
Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens. Xu Z, Sziraki A, Lee J, Zhou W, Cao J Nature biotechnology 37749268 Nat Biotechnol 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/37749268
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Early peanut introduction wins over the HLA-DQA1*01:02 allele in the interplay between environment and genetics. Manohar M, Nadeau KC, Kasowski M The Journal of clinical investigation 34981779 J Clin Invest 2022 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/34981779
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DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance. Zhou N, Choi J, Grothusen G, Kim BJ, Ren D, Cao Z, Liu Y, Li Q, Inamdar A, Beer T, Tang HY, Perkey E, Maillard I, Bonasio R, Shi J, Ruella M, Wan L, Busino L Blood 37235754 Blood 2023 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/37235754
Dysregulation of transcriptional condensates in human disease: mechanisms, biological functions, and open questions. Mathias KM, Liu Y, Wan L Current opinion in genetics & development 38788489 Curr Opin Genet Dev 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38788489
Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia. Wang XQD, Fan D, Han Q, Liu Y, Miao H, Wang X, Li Q, Chen D, Gore H, Himadewi P, Pfeifer GP, Cierpicki T, Grembecka J, Su J, Chong S, Wan L, Zhang X Cancer discovery 36455589 Cancer Discov 2023 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/36455589
Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Song L, Yao X, Li H, Peng B, Boka AP, Liu Y, Chen G, Liu Z, Mathias KM, Xia L, Li Q, Mir M, Li Y, Li H, Wan L Molecular cell 36272410 Mol Cell 2022 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/36272410
Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia. Liu Y, Li Q, Alikarami F, Barrett DR, Mahdavi L, Li H, Tang S, Khan TA, Michino M, Hill C, Song L, Yang L, Li Y, Pokharel SP, Stamford AW, Liverton N, Renzetti LM, Taylor S, Watt GF, Ladduwahetty T, Kargman S, Meinke PT, Foley MA, Shi J, Li H, Carroll M, Chen CW, Gardini A, Maillard I, Huggins DJ, Bernt KM, Wan L Cancer discovery 36053276 Cancer Discov 2022 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/36053276
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HMGB1 restores a dynamic chromatin environment in the presence of linker histone by deforming nucleosomal DNA. Saunders HS, Chio US, Moore CM, Ramani V, Cheng Y, Narlikar GJ bioRxiv : the preprint server for biology 39229246 bioRxiv 2024 Aug 24 https://www.ncbi.nlm.nih.gov/pubmed/39229246
Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers. Yang MG, Richter HJ, Wang S, McNally CP, Harris N, Dhillon S, Maresca M, de Wit E, Willenbring H, Maher J, Goodarzi H, Ramani V bioRxiv : the preprint server for biology 39896524 bioRxiv 2025 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/39896524
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Direct transposition of native DNA for sensitive multimodal single-molecule sequencing. Nanda AS, Wu K, Irkliyenko I, Woo B, Ostrowski MS, Clugston AS, Sayles LC, Xu L, Satpathy AT, Nguyen HG, Alejandro Sweet-Cordero E, Goodarzi H, Kasinathan S, Ramani V Nature genetics 38724748 Nat Genet 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38724748
A Germline Point Mutation in the MYC-FBW7 Phosphodegron Initiates Hematopoietic Malignancies. Freie B, Carroll PA, Varnum-Finney BJ, Ramani V, Bernstein I, Eisenman RN bioRxiv : the preprint server for biology 37961183 bioRxiv 2023 Oct 25 https://www.ncbi.nlm.nih.gov/pubmed/37961183
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Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells. Lampe GD, Liang AR, Zhang DJ, Fernández IS, Sternberg SH bioRxiv : the preprint server for biology 39345383 bioRxiv 2024 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/39345383
Novel recombinases for large DNA insertions. Lampe GD, Sternberg SH Nature biotechnology 36424492 Nat Biotechnol 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36424492
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Evolutionary origins of archaeal and eukaryotic RNA-guided RNA modification in bacterial IS110 transposons. Vaysset H, Meers C, Cury J, Bernheim A, Sternberg SH Nature microbiology 39747689 Nat Microbiol 2025 Jan https://www.ncbi.nlm.nih.gov/pubmed/39747689
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Genome editing with retroelements. Tang S, Sternberg SH Science (New York, N.Y.) 37883564 Science 2023 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/37883564
Bacterial genome engineering using CRISPR-associated transposases. Gelsinger DR, Vo PLH, Klompe SE, Ronda C, Wang HH, Sternberg SH Nature protocols 38216671 Nat Protoc 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38216671
De novo gene synthesis by an antiviral reverse transcriptase. Tang S, Conte V, Zhang DJ, Žedaveinytė R, Lampe GD, Wiegand T, Tang LC, Wang M, Walker MWG, George JT, Berchowitz LE, Jovanovic M, Sternberg SH Science (New York, N.Y.) 39116258 Science 2024 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/39116258
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Geared Toward Applications: A Perspective on Functional Sequence-Controlled Polymers. Yang C, Wu KB, Deng Y, Yuan J, Niu J ACS macro letters 34336395 ACS Macro Lett 2021 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/34336395
Harnessing the power of directed evolution to improve genome editing systems. Su Q, Zhou M, Cheng C, Niu J Current opinion in chemical biology 33725650 Curr Opin Chem Biol 2021 Oct https://www.ncbi.nlm.nih.gov/pubmed/33725650
A General Approach to O-Sulfation by a Sulfur(VI) Fluoride Exchange Reaction. Liu C, Yang C, Hwang S, Ferraro SL, Flynn JP, Niu J Angewandte Chemie (International ed. in English) 32644280 Angew Chem Int Ed Engl 2020 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/32644280
Fluorosulfate as a Latent Sulfate in Peptides and Proteins. Liu C, Liu X, Zhou M, Xia C, Lyu Y, Peng Q, Soni C, Zhou Z, Su Q, Wu Y, Weerapana E, Gao J, Chatterjee A, Lin C, Niu J Journal of the American Chemical Society 37647087 J Am Chem Soc 2023 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/37647087
Genome editor-directed in vivo library diversification. Cheng C, Zhou M, Su Q, Steigmeyer A, Niu J Cell chemical biology 34107297 Cell Chem Biol 2021 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/34107297
"Click handle"-modified 2'-deoxy-2'-fluoroarabino nucleic acid as a synthetic genetic polymer capable of post-polymerization functionalization. Wu KB, Skrodzki CJA, Su Q, Lin J, Niu J Chemical science 35774169 Chem Sci 2022 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/35774169
Heparan sulfate glycomimetics via iterative assembly of "clickable" disaccharides. Yang C, Deng Y, Wang Y, Xia C, Mehta AY, Baker KJ, Samal A, Booneimsri P, Lertmaneedang C, Hwang S, Flynn JP, Cao M, Liu C, Zhu AC, Cummings RD, Lin C, Mohanty U, Niu J Chemical science 37006675 Chem Sci 2023 Mar 29 https://www.ncbi.nlm.nih.gov/pubmed/37006675
Origin recognition complex harbors an intrinsic nucleosome remodeling activity. Li S, Wasserman MR, Yurieva O, Bai L, O'Donnell ME, Liu S Proceedings of the National Academy of Sciences of the United States of America 36215487 Proc Natl Acad Sci U S A 2022 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/36215487
Structure and DNA bridging activity of the essential Rec114â€"Mei4 trimer interface. Liu K, Grasso EM, Pu S, Liu S, Eliezer D, Keeney S bioRxiv : the preprint server for biology 36711595 bioRxiv 2023 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/36711595
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. Abini-Agbomson S, Gretarsson K, Shih RM, Hsieh L, Lou T, De Ioannes P, Vasilyev N, Lee R, Wang M, Simon M, Armache JP, Nudler E, Narlikar G, Liu S, Lu C, Armache KJ bioRxiv : the preprint server for biology 36993485 bioRxiv 2023 Mar 19 https://www.ncbi.nlm.nih.gov/pubmed/36993485
Structure and DNA-bridging activity of the essential Rec114-Mei4 trimer interface. Liu K, Grasso EM, Pu S, Zou M, Liu S, Eliezer D, Keeney S Genes & development 37442580 Genes Dev 2023 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/37442580
Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes. Chua GNL, Watters JW, Olinares PDB, Luo JA, Chait BT, Liu S bioRxiv : the preprint server for biology 37333354 bioRxiv 2023 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/37333354
Head-on and co-directional RNA polymerase collisions orchestrate bidirectional transcription termination. Wang L, Watters JW, Ju X, Lu G, Liu S Molecular cell 36917983 Mol Cell 2023 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/36917983
Nonreciprocal and Conditional Cooperativity Directs the Pioneer Activity of Pluripotency Transcription Factors. Li S, Zheng EB, Zhao L, Liu S Cell reports 31484078 Cell Rep 2019 Sep 3 https://www.ncbi.nlm.nih.gov/pubmed/31484078
Cooperative DNA looping by PRC2 complexes. Lin X, Leicher R, Liu S, Zhang B Nucleic acids research 34057467 Nucleic Acids Res 2021 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/34057467
Single-stranded nucleic acid binding and coacervation by linker histone H1. Leicher R, Osunsade A, Chua GNL, Faulkner SC, Latham AP, Watters JW, Nguyen T, Beckwitt EC, Christodoulou-Rubalcava S, Young PG, Zhang B, David Y, Liu S Nature structural & molecular biology 35484234 Nat Struct Mol Biol 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35484234
Optical tweezers in single-molecule biophysics. Bustamante CJ, Chemla YR, Liu S, Wang MD Nature reviews. Methods primers 34849486 Nat Rev Methods Primers 2021 https://www.ncbi.nlm.nih.gov/pubmed/34849486
The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates. Mickolajczyk KJ, Olinares PDB, Chait BT, Liu S, Kapoor TM eLife 35147499 Elife 2022 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/35147499
Nucleosome-directed replication origin licensing independent of a consensus DNA sequence. Li S, Wasserman MR, Yurieva O, Bai L, O'Donnell ME, Liu S Nature communications 35999198 Nat Commun 2022 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/35999198
Molecular mechanism for direct actin force-sensing by α-catenin. Mei L, Espinosa de Los Reyes S, Reynolds MJ, Leicher R, Liu S, Alushin GM eLife 32969337 Elife 2020 Sep 24 https://www.ncbi.nlm.nih.gov/pubmed/32969337
Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses. Wang L, Johnson ZL, Wasserman MR, Levring J, Chen J, Liu S eLife 32458799 Elife 2020 May 27 https://www.ncbi.nlm.nih.gov/pubmed/32458799
Probing the Interaction Between Chromatin and Chromatin-Associated Complexes with Optical Tweezers. Leicher R, Liu S Methods in molecular biology (Clifton, N.J.) 36063325 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/36063325
Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA. Nguyen T, Li S, Chang JT, Watters JW, Ng H, Osunsade A, David Y, Liu S Nature communications 35810158 Nat Commun 2022 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/35810158
Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA. Chua GNL, Watters JW, Olinares PDB, Begum M, Vostal LE, Luo JA, Chait BT, Liu S Nature structural & molecular biology 39164525 Nat Struct Mol Biol 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/39164525
Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase. Wasserman MR, Schauer GD, O'Donnell ME, Liu S Cell 31348887 Cell 2019 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/31348887
A Tour de Force on the Double Helix: Exploiting DNA Mechanics To Study DNA-Based Molecular Machines. Wasserman MR, Liu S Biochemistry 31251042 Biochemistry 2019 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/31251042
Full-length RNA profiling reveals pervasive bidirectional transcription terminators in bacteria. Ju X, Li D, Liu S Nature microbiology 31308523 Nat Microbiol 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31308523
Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase. Mickolajczyk KJ, Shelton PMM, Grasso M, Cao X, Warrington SE, Aher A, Liu S, Kapoor TM Biophysical journal 33340543 Biophys J 2021 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/33340543
Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin. Leicher R, Ge EJ, Lin X, Reynolds MJ, Xie W, Walz T, Zhang B, Muir TW, Liu S Proceedings of the National Academy of Sciences of the United States of America 33208532 Proc Natl Acad Sci U S A 2020 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/33208532
Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome. Ju X, Li S, Froom R, Wang L, Lilic M, Delbeau M, Campbell EA, Rock JM, Liu S Nature 38418874 Nature 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38418874
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1. Abini-Agbomson S, Gretarsson K, Shih RM, Hsieh L, Lou T, De Ioannes P, Vasilyev N, Lee R, Wang M, Simon MD, Armache JP, Nudler E, Narlikar G, Liu S, Lu C, Armache KJ Molecular cell 37595555 Mol Cell 2023 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/37595555
Tracking cell lineages to improve research reproducibility. Zaaijer S, Groen SC, Sanjana NE Nature biotechnology 34012093 Nat Biotechnol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34012093
Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens. Liscovitch-Brauer N, Montalbano A, Deng J, Méndez-Mancilla A, Wessels HH, Moss NG, Kung CY, Sookdeo A, Guo X, Geller E, Jaini S, Smibert P, Sanjana NE Nature biotechnology 33927415 Nat Biotechnol 2021 Oct https://www.ncbi.nlm.nih.gov/pubmed/33927415
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells. Daniloski Z, Jordan TX, Wessels HH, Hoagland DA, Kasela S, Legut M, Maniatis S, Mimitou EP, Lu L, Geller E, Danziger O, Rosenberg BR, Phatnani H, Smibert P, Lappalainen T, tenOever BR, Sanjana NE Cell 33147445 Cell 2021 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/33147445
Essential transcription factors for induced neuron differentiation. Lu C, Garipler G, Dai C, Roush T, Salome-Correa J, Martin A, Liscovitch-Brauer N, Mazzoni EO, Sanjana NE Nature communications 38102126 Nat Commun 2023 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/38102126
Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling. Yan RE, Corman A, Katgara L, Wang X, Xue X, Gajic ZZ, Sam R, Farid M, Friedman SM, Choo J, Raimondi I, Ganesan S, Katsevich E, Greenfield JP, Dahmane N, Sanjana NE Nature biotechnology 39572737 Nat Biotechnol 2024 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/39572737
Prediction of on-target and off-target activity of CRISPR-Cas13d guide RNAs using deep learning. Wessels HH, Stirn A, Méndez-Mancilla A, Kim EJ, Hart SK, Knowles DA, Sanjana NE Nature biotechnology 37400521 Nat Biotechnol 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/37400521
Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy. Lek A, Zhang Y, Woodman KG, Huang S, DeSimone AM, Cohen J, Ho V, Conner J, Mead L, Kodani A, Pakula A, Sanjana N, King OD, Jones PL, Wagner KR, Lek M, Kunkel LM Science translational medicine 32213627 Sci Transl Med 2020 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/32213627
Generation of a knock-in MAP2-tdTomato reporter human embryonic stem cell line with inducible expression of NEUROG2/1 (NYGCe001-A). Lu C, Sanjana NE Stem cell research 31707212 Stem Cell Res 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31707212
Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus. Kasela S, Daniloski Z, Bollepalli S, Jordan TX, tenOever BR, Sanjana NE, Lappalainen T Genome biology 34425859 Genome Biol 2021 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/34425859
GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease. Li L, Tian E, Chen X, Chao J, Klein J, Qu Q, Sun G, Sun G, Huang Y, Warden CD, Ye P, Feng L, Li X, Cui Q, Sultan A, Douvaras P, Fossati V, Sanjana NE, Riggs AD, Shi Y Cell stem cell 30075130 Cell Stem Cell 2018 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/30075130
The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes. Garipler G, Lu C, Morrissey A, Lopez-Zepeda LS, Pei Y, Vidal SE, Zen Petisco Fiore AP, Aydin B, Stadtfeld M, Ohler U, Mahony S, Sanjana NE, Mazzoni EO Cell reports 35294876 Cell Rep 2022 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/35294876
Cancer genes disfavoring T cell immunity identified via integrated systems approach. Kishton RJ, Patel SJ, Decker AE, Vodnala SK, Cam M, Yamamoto TN, Patel Y, Sukumar M, Yu Z, Ji M, Henning AN, Gurusamy D, Palmer DC, Stefanescu RA, Girvin AT, Lo W, Pasetto A, Malekzadeh P, Deniger DC, Wood KC, Sanjana NE, Restifo NP Cell reports 35926468 Cell Rep 2022 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/35926468
Comprehensive dissection of cis-regulatory elements in a 2.8 Mb topologically associated domain in six human cancers. Caragine CM, Le VT, Mustafa M, Diaz BJ, Morris JA, Müller S, Mendez-Mancilla A, Geller E, Liscovitch-Brauer N, Sanjana NE Nature communications 39948336 Nat Commun 2025 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/39948336
Massively parallel Cas13 screens reveal principles for guide RNA design. Wessels HH, Méndez-Mancilla A, Guo X, Legut M, Daniloski Z, Sanjana NE Nature biotechnology 32518401 Nat Biotechnol 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32518401
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types. Daniloski Z, Jordan TX, Ilmain JK, Guo X, Bhabha G, tenOever BR, Sanjana NE eLife 33570490 Elife 2021 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/33570490
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome. Montalbano A, Canver MC, Sanjana NE Molecular cell 28985510 Mol Cell 2017 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/28985510
Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells. Mimitou EP, Cheng A, Montalbano A, Hao S, Stoeckius M, Legut M, Roush T, Herrera A, Papalexi E, Ouyang Z, Satija R, Sanjana NE, Koralov SB, Smibert P Nature methods 31011186 Nat Methods 2019 May https://www.ncbi.nlm.nih.gov/pubmed/31011186
Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes. Liu EM, Martinez-Fundichely A, Diaz BJ, Aronson B, Cuykendall T, MacKay M, Dhingra P, Wong EWP, Chi P, Apostolou E, Sanjana NE, Khurana E Cell systems 31078526 Cell Syst 2019 May 22 https://www.ncbi.nlm.nih.gov/pubmed/31078526
High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation. Legut M, Daniloski Z, Xue X, McKenzie D, Guo X, Wessels HH, Sanjana NE Cell reports 32130891 Cell Rep 2020 Mar 3 https://www.ncbi.nlm.nih.gov/pubmed/32130891
A genome-wide net to catch and understand cancer. Sanjana NE Science translational medicine 30089637 Sci Transl Med 2018 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/30089637
Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells. Méndez-Mancilla A, Wessels HH, Legut M, Kadina A, Mabuchi M, Walker J, Robb GB, Holden K, Sanjana NE Cell chemical biology 34343484 Cell Chem Biol 2022 Feb 17 https://www.ncbi.nlm.nih.gov/pubmed/34343484
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. Wei W, Geer MJ, Guo X, Dolgalev I, Sanjana NE, Neel BG The Journal of experimental medicine 36820830 J Exp Med 2023 May 1 https://www.ncbi.nlm.nih.gov/pubmed/36820830
Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq. Wessels HH, Méndez-Mancilla A, Hao Y, Papalexi E, Mauck WM 3rd, Lu L, Morris JA, Mimitou EP, Smibert P, Sanjana NE, Satija R Nature methods 36550277 Nat Methods 2023 Jan https://www.ncbi.nlm.nih.gov/pubmed/36550277
Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction. Shi X, Lu C, Corman A, Nikish A, Zhou Y, Platt RJ, Iossifov I, Zhang F, Pan JQ, Sanjana NE American journal of human genetics 37802044 Am J Hum Genet 2023 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/37802044
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens. Morris JA, Caragine C, Daniloski Z, Domingo J, Barry T, Lu L, Davis K, Ziosi M, Glinos DA, Hao S, Mimitou EP, Smibert P, Roeder K, Katsevich E, Lappalainen T, Sanjana NE Science (New York, N.Y.) 37141313 Science 2023 May 19 https://www.ncbi.nlm.nih.gov/pubmed/37141313
Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells. Liang WW, Müller S, Hart SK, Wessels HH, Méndez-Mancilla A, Sookdeo A, Choi O, Caragine CM, Corman A, Lu L, Kolumba O, Williams B, Sanjana NE Cell 39532094 Cell 2024 Dec 26 https://www.ncbi.nlm.nih.gov/pubmed/39532094
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types. Daniloski Z, Jordan TX, Ilmain JK, Guo X, Bhabha G, tenOever BR, Sanjana NE bioRxiv : the preprint server for biology 32587969 bioRxiv 2020 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/32587969
Expanding the Scope of Bacterial CRISPR Activation with PAM-Flexible dCas9 Variants. Kiattisewee C, Karanjia AV, Legut M, Daniloski Z, Koplik SE, Nelson J, Kleinstiver BP, Sanjana NE, Carothers JM, Zalatan JG ACS synthetic biology 36378874 ACS Synth Biol 2022 Dec 16 https://www.ncbi.nlm.nih.gov/pubmed/36378874
A genome-scale screen for synthetic drivers of T cell proliferation. Legut M, Gajic Z, Guarino M, Daniloski Z, Rahman JA, Xue X, Lu C, Lu L, Mimitou EP, Hao S, Davoli T, Diefenbach C, Smibert P, Sanjana NE Nature 35296855 Nature 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35296855
Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens. Guo X, Rahman JA, Wessels HH, Méndez-Mancilla A, Haro D, Chen X, Sanjana NE Cell genomics 35664829 Cell Genom 2021 Oct 13 https://www.ncbi.nlm.nih.gov/pubmed/35664829
Recurrent somatic mutations as predictors of immunotherapy response. Gajic ZZ, Deshpande A, Legut M, Imieliński M, Sanjana NE Nature communications 35803911 Nat Commun 2022 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/35803911
Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus. Kasela S, Daniloski Z, Jordan TX, tenOever BR, Sanjana NE, Lappalainen T medRxiv : the preprint server for health sciences 33880488 medRxiv 2021 Apr 13 https://www.ncbi.nlm.nih.gov/pubmed/33880488
Overexpression of NEUROG2 and NEUROG1 in human embryonic stem cells produces a network of excitatory and inhibitory neurons. Lu C, Shi X, Allen A, Baez-Nieto D, Nikish A, Sanjana NE, Pan JQ FASEB journal : official publication of the Federation of American Societies for Experimental Biology 30698461 FASEB J 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30698461
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H Proceedings of the National Academy of Sciences of the United States of America 38743625 Proc Natl Acad Sci U S A 2024 May 21 https://www.ncbi.nlm.nih.gov/pubmed/38743625
Next-generation forward genetic screens: uniting high-throughput perturbations with single-cell analysis. Morris JA, Sun JS, Sanjana NE Trends in genetics : TIG 37989654 Trends Genet 2024 Feb https://www.ncbi.nlm.nih.gov/pubmed/37989654
Non-linear transcriptional responses to gradual modulation of transcription factor dosage. Domingo J, Minaeva M, Morris JA, Ghatan S, Ziosi M, Sanjana NE, Lappalainen T bioRxiv : the preprint server for biology 38464330 bioRxiv 2024 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/38464330
Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox. Schertzer MD, Stirn A, Isaev K, Pereira L, Das A, Harbison C, Park SH, Wessels HH, Sanjana NE, Knowles DA bioRxiv : the preprint server for biology 37745416 bioRxiv 2023 Sep 13 https://www.ncbi.nlm.nih.gov/pubmed/37745416
Precise RNA targeting with CRISPR-Cas13d. Hart SK, Müller S, Wessels HH, Méndez-Mancilla A, Drabavicius G, Choi O, Sanjana NE Nature biotechnology 39934271 Nat Biotechnol 2025 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/39934271
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A metabolic pathway for bile acid dehydroxylation by the gut microbiome. Funabashi M, Grove TL, Wang M, Varma Y, McFadden ME, Brown LC, Guo C, Higginbottom S, Almo SC, Fischbach MA Nature 32555455 Nature 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32555455
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY Nature 32461639 Nature 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32461639
Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection. Zhang W, Lyu M, Bessman NJ, Xie Z, Arifuzzaman M, Yano H, Parkhurst CN, Chu C, Zhou L, Putzel GG, Li TT, Jin WB, Zhou J, JRI Live Cell Bank, Hu H, Tsou AM, Guo CJ, Artis D Cell 36240781 Cell 2022 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/36240781
Gut bacteria-derived serotonin promotes immune tolerance in early life. Sanidad KZ, Rager SL, Carrow HC, Ananthanarayanan A, Callaghan R, Hart LR, Li T, Ravisankar P, Brown JA, Amir M, Jin JC, Savage AR, Luo R, Rowdo FM, Martin ML, Silver RB, Guo CJ, Krumsiek J, Inohara N, Zeng MY Science immunology 38489352 Sci Immunol 2024 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/38489352
Dietary fiber is a critical determinant of pathologic ILC2 responses and intestinal inflammation. Arifuzzaman M, Won TH, Yano H, Uddin J, Emanuel ER, Hu E, Zhang W, Li TT, Jin WB, Grier A, Kashyap S, JRI Live Cell Bank, Guo CJ, Schroeder FC, Artis D The Journal of experimental medicine 38506708 J Exp Med 2024 May 6 https://www.ncbi.nlm.nih.gov/pubmed/38506708
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology. Li TT, Chen X, Huo D, Arifuzzaman M, Qiao S, Jin WB, Shi H, Li XV, JRI Live Cell Bank Consortium, Iliev ID, Artis D, Guo CJ Cell host & microbe 38657606 Cell Host Microbe 2024 May 8 https://www.ncbi.nlm.nih.gov/pubmed/38657606
Depletion of microbiome-derived molecules in the host using Clostridium genetics. Guo CJ, Allen BM, Hiam KJ, Dodd D, Van Treuren W, Higginbottom S, Nagashima K, Fischer CR, Sonnenburg JL, Spitzer MH, Fischbach MA Science (New York, N.Y.) 31831639 Science 2019 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/31831639
Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection. Brown JA, Sanidad KZ, Lucotti S, Lieber CM, Cox RM, Ananthanarayanan A, Basu S, Chen J, Shan M, Amir M, Schmidt F, Weisblum Y, Cioffi M, Li T, Rowdo FM, Martin ML, Guo CJ, Lyssiotis C, Layden BT, Dannenberg AJ, Bieniasz PD, Lee B, Inohara N, Matei I, Plemper RK, Zeng MY Gut microbes 35915556 Gut Microbes 2022 Jan-Dec https://www.ncbi.nlm.nih.gov/pubmed/35915556
Functional characterization of helminth-associated Clostridiales reveals covariates of Treg differentiation. Sargsian S, Mondragón-Palomino O, Lejeune A, Ercelen D, Jin WB, Varghese A, Lim YAL, Guo CJ, Loke P, Cadwell K Microbiome 38730492 Microbiome 2024 May 10 https://www.ncbi.nlm.nih.gov/pubmed/38730492
Automated detection of axonal damage along white matter tracts in acute severe traumatic brain injury. Maffei C, Gilmore N, Snider SB, Foulkes AS, Bodien YG, Yendiki A, Edlow BL NeuroImage. Clinical 36529035 Neuroimage Clin 2023 https://www.ncbi.nlm.nih.gov/pubmed/36529035
Measuring Consciousness in the Intensive Care Unit. Edlow BL, Fecchio M, Bodien YG, Comanducci A, Rosanova M, Casarotto S, Young MJ, Li J, Dougherty DD, Koch C, Tononi G, Massimini M, Boly M Neurocritical care 37029315 Neurocrit Care 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/37029315
Emerging Consciousness at a Clinical Crossroads. Young MJ, Edlow BL AJOB neuroscience 33960885 AJOB Neurosci 2021 Apr-Sep https://www.ncbi.nlm.nih.gov/pubmed/33960885
Update on neuroimaging in disorders of consciousness. Sanz LRD, Thibaut A, Edlow BL, Laureys S, Gosseries O Current opinion in neurology 34054109 Curr Opin Neurol 2021 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/34054109
Joint cortical registration of geometry and function using semi-supervised learning. Li J, Tuckute G, Fedorenko E, Edlow BL, Fischl B, Dalca AV ArXiv 37744470 ArXiv 2023 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/37744470
A state-space model for dynamic functional connectivity. Chakravarty S, Threlkeld ZD, Bodien YG, Edlow BL, Brown EN Conference record. Asilomar Conference on Signals, Systems & Computers 32801606 Conf Rec Asilomar Conf Signals Syst Comput 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/32801606
Common Data Elements for COVID-19 Neuroimaging: A GCS-NeuroCOVID Proposal. Edlow BL, Boly M, Chou SH, Fischer D, Kondziella D, Li LM, Mac Donald CL, McNett M, Newcombe VFJ, Stevens RD, Menon DK, GCS-NeuroCOVID Neurocritical care 33575956 Neurocrit Care 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33575956
Personalized Connectome Mapping to Guide Targeted Therapy and Promote Recovery of Consciousness in the Intensive Care Unit. Edlow BL, Barra ME, Zhou DW, Foulkes AS, Snider SB, Threlkeld ZD, Chakravarty S, Kirsch JE, Chan ST, Meisler SL, Bleck TP, Fins JJ, Giacino JT, Hochberg LR, Solt K, Brown EN, Bodien YG Neurocritical care 32794142 Neurocrit Care 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32794142
Mapping the subcortical connectivity of the human default mode network. Li J, Curley WH, Guerin B, Dougherty DD, Dalca AV, Fischl B, Horn A, Edlow BL NeuroImage 34838949 Neuroimage 2021 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/34838949
Common data elements for disorders of consciousness. Edlow BL, Claassen J, Suarez JI Neurocritical care 38291278 Neurocrit Care 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38291278
Model-based navigation of transcranial focused ultrasound neuromodulation in humans: Application to targeting the amygdala and thalamus. Daneshzand M, Guerin B, Kotlarz P, Chou T, Dougherty DD, Edlow BL, Nummenmaa A Brain stimulation 39094682 Brain Stimul 2024 Jul-Aug https://www.ncbi.nlm.nih.gov/pubmed/39094682
Cortical Lesion Expansion in Chronic Traumatic Brain Injury. Freeman HJ, Atalay AS, Li J, Sobczak E, Gilmore N, Snider SB, Healy BC, Carrington H, Selmanovic E, Pruyser A, Bura L, Sheppard D, Hunt D, Seifert AC, Bodien YG, Hoffman JM, Mac Donald CL, Dams-O'Connor K, Edlow BL medRxiv : the preprint server for health sciences 38978662 medRxiv 2025 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/38978662
A human brain network linked to restoration of consciousness after deep brain stimulation. Warren AEL, Raguž M, Friedrich H, Schaper FLWVJ, Tasserie J, Snider SB, Li J, Chua MMJ, Butenko K, Friedrich MU, Jha R, Iglesias JE, Carney PW, Fischer D, Fox MD, Boes AD, Edlow BL, Horn A, Chudy D, Rolston JD medRxiv : the preprint server for health sciences 39484242 medRxiv 2024 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/39484242
Cortical lesions and focal white matter injury are associated with attentional performance in chronic traumatic brain injury. Snider SB, Gilmore N, Freeman HJ, Maffei C, Atalay A, Kumar RG, Li LM, Shi H, Bodien YG, Mac Donald CL, Dams-O'Connor K, Edlow BL Brain communications 39926612 Brain Commun 2025 https://www.ncbi.nlm.nih.gov/pubmed/39926612
7 Tesla MRI of the ex vivo human brain at 100 micron resolution. Edlow BL, Mareyam A, Horn A, Polimeni JR, Witzel T, Tisdall MD, Augustinack JC, Stockmann JP, Diamond BR, Stevens A, Tirrell LS, Folkerth RD, Wald LL, Fischl B, van der Kouwe A Scientific data 31666530 Sci Data 2019 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/31666530
EEG Correlates of Language Function in Traumatic Disorders of Consciousness. Chatelle C, Rosenthal ES, Bodien YG, Spencer-Salmon CA, Giacino JT, Edlow BL Neurocritical care 31900883 Neurocrit Care 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/31900883
Ascending arousal network connectivity during recovery from traumatic coma. Snider SB, Bodien YG, Frau-Pascual A, Bianciardi M, Foulkes AS, Edlow BL NeuroImage. Clinical 33395992 Neuroimage Clin 2020 https://www.ncbi.nlm.nih.gov/pubmed/33395992
Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study. Nolan AL, Petersen C, Iacono D, Mac Donald CL, Mukherjee P, van der Kouwe A, Jain S, Stevens A, Diamond BR, Wang R, Markowitz AJ, Fischl B, Perl DP, Manley GT, Keene CD, Diaz-Arrastia R, Edlow BL, TRACK-TBI Investigators Journal of neurotrauma 33412995 J Neurotrauma 2021 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/33412995
Early Seizures Are Predictive of Worse Health-Related Quality of Life at Follow-Up After Intracerebral Hemorrhage. Naidech AM, Weaver B, Maas M, Bleck TP, VanHaerents S, Schuele SU Critical care medicine 33729725 Crit Care Med 2021 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/33729725
Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies. Edlow BL, Claassen J, Schiff ND, Greer DM Nature reviews. Neurology 33318675 Nat Rev Neurol 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33318675
Reemergence of the language network during recovery from severe traumatic brain injury: A pilot functional MRI study. Coffey BJ, Threlkeld ZD, Foulkes AS, Bodien YG, Edlow BL Brain injury 34546806 Brain Inj 2021 Nov 10 https://www.ncbi.nlm.nih.gov/pubmed/34546806
Dopaminergic modulation of human consciousness via default mode network connectivity. Edlow BL Proceedings of the National Academy of Sciences of the United States of America 34330840 Proc Natl Acad Sci U S A 2021 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/34330840
Early Rehabilitation for Patients with Disorders of Consciousness after Severe COVID-19. Edlow BL Neurocritical care 34617252 Neurocrit Care 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/34617252
The Quest for Covert Consciousness: Bringing Neuroethics to the Bedside. Young MJ, Edlow BL Neurology 33653901 Neurology 2021 May 11 https://www.ncbi.nlm.nih.gov/pubmed/33653901
Neuroprognostication: a conceptual framework. Fischer D, Edlow BL, Giacino JT, Greer DM Nature reviews. Neurology 35352033 Nat Rev Neurol 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35352033
Electrophysiological correlates of thalamocortical function in acute severe traumatic brain injury. Curley WH, Bodien YG, Zhou DW, Conte MM, Foulkes AS, Giacino JT, Victor JD, Schiff ND, Edlow BL Cortex; a journal devoted to the study of the nervous system and behavior 35569326 Cortex 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35569326
Predicting Functional Dependency in Patients with Disorders of Consciousness: A TBI-Model Systems and TRACK-TBI Study. Snider SB, Temkin NR, Barber J, Edlow BL, Giacino JT, Hammond FM, Izzy S, Kowalski RG, Markowitz AJ, Rovito CA, Shih SL, Zafonte RD, Manley GT, Bodien YG, TRACK-TBI investigators Annals of neurology 37470289 Ann Neurol 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37470289
Severe cerebral edema in substance-related cardiac arrest patients. Kulpanowski AM, Copen WA, Hancock BL, Rosenthal ES, Schoenfeld DA, Dodelson JA, Edlow BL, Kimberly WT, Amorim E, Westover MB, Ning MM, Schaefer PW, Malhotra R, Giacino JT, Greer DM, Wu O Resuscitation 35149137 Resuscitation 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35149137
Conventional and Investigational Approaches Leveraging Clinical EEG for Prognosis in Acute Disorders of Consciousness. Curley WH, Comanducci A, Fecchio M Seminars in neurology 36100227 Semin Neurol 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/36100227
Brain-Computer Interfaces for Communication in Patients with Disorders of Consciousness: A Gap Analysis and Scientific Roadmap. Schiff ND, Diringer M, Diserens K, Edlow BL, Gosseries O, Hill NJ, Hochberg LR, Ismail FY, Meyer IA, Mikell CB, Mofakham S, Molteni E, Polizzotto L, Shah SA, Stevens RD, Thengone D, and the Curing Coma Campaign and its Contributing Members Neurocritical care 38286946 Neurocrit Care 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38286946
Defining the boundary between life and death: New insights from neuropathology. Edlow BL, Kinney HC Journal of neuropathology and experimental neurology 36519398 J Neuropathol Exp Neurol 2022 Dec 19 https://www.ncbi.nlm.nih.gov/pubmed/36519398
One-Year Outcomes in Disorders of Consciousness Associated with COVID-19. Fischer D, Edlow BL Neurocritical care 36324001 Neurocrit Care 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36324001
Correcting cardiorespiratory noise in resting-state functional MRI data acquired in critically ill patients. Chan ST, Sanders WR, Fischer D, Kirsch JE, Napadow V, Bodien YG, Edlow BL Brain communications 36382222 Brain Commun 2022 https://www.ncbi.nlm.nih.gov/pubmed/36382222
What is a minimal clinically important difference for clinical trials in patients with disorders of consciousness? a novel probabilistic approach. Monti MM, Spivak NM, Edlow BL, Bodien YG PloS one 37616196 PLoS One 2023 https://www.ncbi.nlm.nih.gov/pubmed/37616196
Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness. Edlow BL, Olchanyi M, Freeman HJ, Li J, Maffei C, Snider SB, Zöllei L, Iglesias JE, Augustinack J, Bodien YG, Haynes RL, Greve DN, Diamond BR, Stevens A, Giacino JT, Destrieux C, van der Kouwe A, Brown EN, Folkerth RD, Fischl B, Kinney HC Science translational medicine 38691619 Sci Transl Med 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38691619
Cross-regional coordination of activity in the human brain during autobiographical self-referential processing. Stieger JR, Pinheiro-Chagas P, Fang Y, Li J, Lusk Z, Perry CM, Girn M, Contreras D, Chen Q, Huguenard JR, Spreng RN, Edlow BL, Wagner AD, Buch V, Parvizi J Proceedings of the National Academy of Sciences of the United States of America 39078679 Proc Natl Acad Sci U S A 2024 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/39078679
Three-dimensional fiber orientation mapping of the human brain at micrometer resolution. Liu CJ, Ammon W, Jones RJ, Nolan JC, Gong D, Maffei C, Edlow BL, Augustinack JC, Magnain C, Yendiki A, Villiger M, Fischl B, Wang H Research square 39149445 Res Sq 2024 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/39149445
Automated Measurement of Cerebral Hemorrhagic Contusions and Outcomes After Traumatic Brain Injury in the TRACK-TBI Study. Snider SB, Temkin NR, Sun X, Stubbs JL, Rademaker QJ, Markowitz AJ, Rosenthal ES, Diaz-Arrastia R, Fox MD, Manley GT, Jain S, Edlow BL, TRACK-TBI Investigators JAMA network open 39212991 JAMA Netw Open 2024 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/39212991
MRI in disorders of consciousness. Snider SB, Edlow BL Current opinion in neurology 33044234 Curr Opin Neurol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33044234
Unmasking Covert Language Processing in the Intensive Care Unit with Electroencephalography. Edlow BL, Naccache L Annals of neurology 33491250 Ann Neurol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33491250
Multicenter prospective study on predictors of short-term outcome in disorders of consciousness. Estraneo A, Fiorenza S, Magliacano A, Formisano R, Mattia D, Grippo A, Romoli AM, Angelakis E, Cassol H, Thibaut A, Gosseries O, Lamberti G, Noé E, Bagnato S, Edlow BL, Chatelle C, Lejeune N, Veeramuthu V, Bartolo M, Toppi J, Zasler N, Schnakers C, Trojano L, IBIA DoC-SIG Neurology 32661102 Neurology 2020 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/32661102
Toward Uniform Insurer Coverage for Functional MRI Following Severe Brain Injury. Young MJ, Bodien YG, Freeman HJ, Fecchio M, Edlow BL The Journal of head trauma rehabilitation 36854104 J Head Trauma Rehabil 2023 Jul-Aug 01 https://www.ncbi.nlm.nih.gov/pubmed/36854104
Sustaining wakefulness: Brainstem connectivity in human consciousness. Edlow BL, Olchanyi M, Freeman HJ, Li J, Maffei C, Snider SB, Zöllei L, Iglesias JE, Augustinack J, Bodien YG, Haynes RL, Greve DN, Diamond BR, Stevens A, Giacino JT, Destrieux C, van der Kouwe A, Brown EN, Folkerth RD, Fischl B, Kinney HC bioRxiv : the preprint server for biology 37502983 bioRxiv 2023 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/37502983
Stability of extemporaneously prepared preservative-free methylphenidate 5 mg/mL intravenous solution. Barra ME, Edlow BL, Lund JT, DeSanctis KS, Vetrano J, Reilly-Tremblay C, Zhang ER, Bodien YG, Brown EN, Solt K American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 34788364 Am J Health Syst Pharm 2022 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/34788364
Feasibility and Validity of the Coma Recovery Scale-Revised for Accelerated Standardized Testing: A Practical Assessment Tool for Detecting Consciousness in the Intensive Care Unit. Bodien YG, Vora I, Barra A, Chiang K, Chatelle C, Goostrey K, Martens G, Malone C, Mello J, Parlman K, Ranford J, Sterling A, Waters AB, Hirschberg R, Katz DI, Mazwi N, Ni P, Velmahos G, Waak K, Edlow BL, Giacino JT Annals of neurology 37488068 Ann Neurol 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37488068
Prognostication in Acute Neurological Emergencies. Sloane KL, Miller JJ, Piquet A, Edlow BL, Rosenthal ES, Singhal AB Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 35007934 J Stroke Cerebrovasc Dis 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35007934
Risk factors for 2-year mortality in patients with prolonged disorders of consciousness: An international multicentre study. Estraneo A, Magliacano A, Fiorenza S, Formisano R, Grippo A, Angelakis E, Cassol H, Thibaut A, Gosseries O, Lamberti G, Noé E, Bagnato S, Edlow BL, Chatelle C, Lejeune N, Veeramuthu V, Bartolo M, Mattia D, Toppi J, Zasler N, Schnakers C, Trojano L European journal of neurology 34657359 Eur J Neurol 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/34657359
Mapping a memory disorder using functional network analysis. Edlow BL Acta neurologica Scandinavica 34231225 Acta Neurol Scand 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34231225
Joint super-resolution and synthesis of 1 mm isotropic MP-RAGE volumes from clinical MRI exams with scans of different orientation, resolution and contrast. Iglesias JE, Billot B, Balbastre Y, Tabari A, Conklin J, Gilberto González R, Alexander DC, Golland P, Edlow BL, Fischl B, Alzheimer’s Disease Neuroimaging Initiative NeuroImage 34048902 Neuroimage 2021 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/34048902
Pharmacologic Therapies to Promote Recovery of Consciousness. Barra ME, Edlow BL, Brophy GM Seminars in neurology 36100228 Semin Neurol 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/36100228
Disclosing Results of Tests for Covert Consciousness: A Framework for Ethical Translation. Young MJ, Kazazian K, Fischer D, Lissak IA, Bodien YG, Edlow BL Neurocritical care 38243150 Neurocrit Care 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38243150
SynthSR: A public AI tool to turn heterogeneous clinical brain scans into high-resolution T1-weighted images for 3D morphometry. Iglesias JE, Billot B, Balbastre Y, Magdamo C, Arnold SE, Das S, Edlow BL, Alexander DC, Golland P, Fischl B Science advances 36724222 Sci Adv 2023 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/36724222
Characterizing coma in large vessel occlusion stroke. Young MJ, Awad A, Andreev A, Bonkhoff AK, Schirmer MD, Dmytriw AA, Vranic JE, Rabinov JD, Doron O, Stapleton CJ, Das AS, Edlow BL, Singhal AB, Rost NS, Patel AB, Regenhardt RW Journal of neurology 38366071 J Neurol 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38366071
Coma Prognostication After Acute Brain Injury: A Review. Fischer D, Edlow BL JAMA neurology 38436946 JAMA Neurol 2024 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/38436946
Cognitive Motor Dissociation in Disorders of Consciousness. Bodien YG, Allanson J, Cardone P, Bonhomme A, Carmona J, Chatelle C, Chennu S, Conte M, Dehaene S, Finoia P, Heinonen G, Hersh JE, Kamau E, Lawrence PK, Lupson VC, Meydan A, Rohaut B, Sanders WR, Sitt JD, Soddu A, Valente M, Velazquez A, Voss HU, Vrosgou A, Claassen J, Edlow BL, Fins JJ, Gosseries O, Laureys S, Menon D, Naccache L, Owen AM, Pickard J, Stamatakis EA, Thibaut A, Victor JD, Giacino JT, Bagiella E, Schiff ND The New England journal of medicine 39141852 N Engl J Med 2024 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/39141852
Visualizing Effective Connectivity in the Human Brain. Atalay AS, Fecchio M, Edlow BL bioRxiv : the preprint server for biology 40161749 bioRxiv 2025 Mar 10 https://www.ncbi.nlm.nih.gov/pubmed/40161749
Acute biomarkers of consciousness are associated with recovery after severe traumatic brain injury. Bodien YG, Fecchio M, Gilmore N, Freeman HJ, Sanders WR, Meydan A, Lawrence PK, Atalay AS, Kirsch J, Healy BC, Edlow BL medRxiv : the preprint server for health sciences 40093212 medRxiv 2025 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/40093212
Predicting Long-Term Recovery of Consciousness in Prolonged Disorders of Consciousness Based on Coma Recovery Scale-Revised Subscores: Validation of a Machine Learning-Based Prognostic Index. Magliacano A, Liuzzi P, Formisano R, Grippo A, Angelakis E, Thibaut A, Gosseries O, Lamberti G, Noé E, Bagnato S, Edlow BL, Lejeune N, Veeramuthu V, Trojano L, Zasler N, Schnakers C, Bartolo M, Mannini A, Estraneo A, IBIA DoC-SIG Brain sciences 36672033 Brain Sci 2022 Dec 27 https://www.ncbi.nlm.nih.gov/pubmed/36672033
Prolonged Unconsciousness is Common in COVID-19 and Associated with Hypoxemia. Waldrop G, Safavynia SA, Barra ME, Agarwal S, Berlin DA, Boehme AK, Brodie D, Choi JM, Doyle K, Fins JJ, Ganglberger W, Hoffman K, Mittel AM, Roh D, Mukerji SS, Der Nigoghossian C, Park S, Schenck EJ, Salazar-Schicchi J, Shen Q, Sholle E, Velazquez AG, Walline MC, Westover MB, Brown EN, Victor J, Edlow BL, Schiff ND, Claassen J Annals of neurology 35254675 Ann Neurol 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35254675
Transcranial Pulsed-Current Stimulation versus Transcranial Direct Current Stimulation in Patients with Disorders of Consciousness: A Pilot, Sham-Controlled Cross-Over Double-Blind Study. Barra A, Rosenfelder M, Mortaheb S, Carrière M, Martens G, Bodien YG, Morales-Quezada L, Bender A, Laureys S, Thibaut A, Fregni F Brain sciences 35447961 Brain Sci 2022 Mar 24 https://www.ncbi.nlm.nih.gov/pubmed/35447961
Therapies to Restore Consciousness in Patients with Severe Brain Injuries: A Gap Analysis and Future Directions. Edlow BL, Sanz LRD, Polizzotto L, Pouratian N, Rolston JD, Snider SB, Thibaut A, Stevens RD, Gosseries O, Curing Coma Campaign and its contributing members Neurocritical care 34236624 Neurocrit Care 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34236624
Optimizing the accuracy of cortical volumetric analysis in traumatic brain injury. Diamond BR, Donald CLM, Frau-Pascual A, Snider SB, Fischl B, Dams-O'Connor K, Edlow BL MethodsX 32760659 MethodsX 2020 https://www.ncbi.nlm.nih.gov/pubmed/32760659
Location of Subcortical Microbleeds and Recovery of Consciousness After Severe Traumatic Brain Injury. Bianciardi M, Izzy S, Rosen BR, Wald LL, Edlow BL Neurology 34050005 Neurology 2021 Jul 13 https://www.ncbi.nlm.nih.gov/pubmed/34050005
The neuroethics of disorders of consciousness: a brief history of evolving ideas. Young MJ, Bodien YG, Giacino JT, Fins JJ, Truog RD, Hochberg LR, Edlow BL Brain : a journal of neurology 34347037 Brain 2021 Dec 16 https://www.ncbi.nlm.nih.gov/pubmed/34347037
Long-Term Recovery from Disordered Consciousness Associated with COVID-19. Fischer D, Edlow BL Neurocritical care 34642843 Neurocrit Care 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34642843
Intact Brain Network Function in an Unresponsive Patient with COVID-19. Fischer D, Threlkeld ZD, Bodien YG, Kirsch JE, Huang SY, Schaefer PW, Rapalino O, Hochberg LR, Rosen BR, Edlow BL Annals of neurology 32613682 Ann Neurol 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32613682
Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19. Conklin J, Frosch MP, Mukerji SS, Rapalino O, Maher MD, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, Shaw B, Lemieux JE, Sabeti PC, Branda JA, Brown EN, Westover MB, Huang SY, Edlow BL Journal of the neurological sciences 33497950 J Neurol Sci 2021 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/33497950
Recovery Potential in Patients Who Died After Withdrawal of Life-Sustaining Treatment: A TRACK-TBI Propensity Score Analysis. Sanders WR, Barber JK, Temkin NR, Foreman B, Giacino JT, Williamson T, Edlow BL, Manley GT, Bodien YG Journal of neurotrauma 38739032 J Neurotrauma 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/38739032
Ictal fMRI: Mapping Seizure Topography with Rhythmic BOLD Oscillations. Fischer D, Rapalino O, Fecchio M, Edlow BL Brain sciences 36552169 Brain Sci 2022 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/36552169
Increased task-relevant fMRI responsiveness in comatose cardiac arrest patients is associated with improved neurologic outcomes. Dhakal K, Rosenthal ES, Kulpanowski AM, Dodelson JA, Wang Z, Cudemus-Deseda G, Villien M, Edlow BL, Presciutti AM, Januzzi JL, Ning M, Taylor Kimberly W, Amorim E, Brandon Westover M, Copen WA, Schaefer PW, Giacino JT, Greer DM, Wu O Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 37728641 J Cereb Blood Flow Metab 2024 Jan https://www.ncbi.nlm.nih.gov/pubmed/37728641
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury. Kumar RG, Selmanovic E, Gilmore N, Spielman L, Li LM, Hoffman JM, Bodien YG, Snider SB, Freeman HJ, de Souza NL, Donald CLM, Edlow BL, Dams-O'Connor K medRxiv : the preprint server for health sciences 39974133 medRxiv 2025 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/39974133
Covert cortical processing: a diagnosis in search of a definition. Young MJ, Fecchio M, Bodien YG, Edlow BL Neuroscience of consciousness 38327828 Neurosci Conscious 2024 https://www.ncbi.nlm.nih.gov/pubmed/38327828
Are disorders of consciousness 'dis'connection or 'dys'connection syndromes? Edlow BL, Massimini M Brain communications 38410155 Brain Commun 2023 https://www.ncbi.nlm.nih.gov/pubmed/38410155
Quantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy. Chen Y, Li S, Ge W, Jing J, Chen HY, Doherty D, Herman A, Kaleem S, Ding K, Osman G, Swisher CB, Smith C, Maciel CB, Alkhachroum A, Lee JW, Dhakar MB, Gilmore EJ, Sivaraju A, Hirsch LJ, Omay SB, Blumenfeld H, Sheth KN, Struck AF, Edlow BL, Westover MB, Kim JA Journal of neurology, neurosurgery, and psychiatry 36241423 J Neurol Neurosurg Psychiatry 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/36241423
Covert consciousness. Young MJ, Edlow BL, Bodien YG NeuroRehabilitation 38217619 NeuroRehabilitation 2024 https://www.ncbi.nlm.nih.gov/pubmed/38217619
Alpha coherence is a network signature of cognitive recovery from disorders of consciousness. Zhou DW, Conte MM, Curley WH, Spencer-Salmon CA, Chatelle C, Rosenthal ES, Bodien YG, Victor JD, Schiff ND, Brown EN, Edlow BL medRxiv : the preprint server for health sciences 39417105 medRxiv 2024 Oct 10 https://www.ncbi.nlm.nih.gov/pubmed/39417105
Oral delivery of peptide therapeutics in infants: Challenges and opportunities. Gleeson JP, Fein KC, Whitehead KA Advanced drug delivery reviews 33774115 Adv Drug Deliv Rev 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33774115
The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery. Lamson NG, Fein KC, Gleeson JP, Newby AN, Xian S, Cochran K, Chaudhary N, Melamed JR, Ball RL, Suri K, Ahuja V, Zhang A, Berger A, Kolodieznyi D, Schmidt BF, Silva GL, Whitehead KA Proceedings of the National Academy of Sciences of the United States of America 35943988 Proc Natl Acad Sci U S A 2022 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/35943988
Non-Viral RNA Delivery During Pregnancy: Opportunities and Challenges. Chaudhary N, Newby AN, Whitehead KA Small (Weinheim an der Bergstrasse, Germany) 38145340 Small 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/38145340
Branched-Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice. Petersen DMS, Weiss RM, Hajj KA, Yerneni SS, Chaudhary N, Newby AN, Arral ML, Whitehead KA Advanced healthcare materials 38888972 Adv Healthc Mater 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/38888972
The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism. Strelkova Petersen DM, Chaudhary N, Arral ML, Weiss RM, Whitehead KA European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 37838143 Eur J Pharm Biopharm 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37838143
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs. LoPresti ST, Arral ML, Chaudhary N, Whitehead KA Journal of controlled release : official journal of the Controlled Release Society 35346768 J Control Release 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35346768
mRNA vaccines for infectious diseases: principles, delivery and clinical translation. Chaudhary N, Weissman D, Whitehead KA Nature reviews. Drug discovery 34433919 Nat Rev Drug Discov 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34433919
Placental drug transport and fetal exposure during pregnancy is determined by drug molecular size, chemistry, and conformation. Fein KC, Arral ML, Kim JS, Newby AN, Whitehead KA Journal of controlled release : official journal of the Controlled Release Society 37473809 J Control Release 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37473809
Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes. Chaudhary N, Newby AN, Arral ML, Yerneni SS, LoPresti ST, Doerfler R, Petersen DMS, Montoya C, Kim JS, Fox B, Coon T, Malaney A, Sadovsky Y, Whitehead KA Proceedings of the National Academy of Sciences of the United States of America 38437545 Proc Natl Acad Sci U S A 2024 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/38437545
Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations. Gleeson JP, Chaudhary N, Fein KC, Doerfler R, Hredzak-Showalter P, Whitehead KA Science advances 35767604 Sci Adv 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35767604
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer. Melamed JR, Yerneni SS, Arral ML, LoPresti ST, Chaudhary N, Sehrawat A, Muramatsu H, Alameh MG, Pardi N, Weissman D, Gittes GK, Whitehead KA Science advances 36706177 Sci Adv 2023 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/36706177
Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d. Chaudhary N, Kasiewicz LN, Newby AN, Arral ML, Yerneni SS, Melamed JR, LoPresti ST, Fein KC, Strelkova Petersen DM, Kumar S, Purwar R, Whitehead KA Nature biomedical engineering 39363106 Nat Biomed Eng 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/39363106
Maternal milk cell components are uptaken by infant liver macrophages via extracellular vesicle mediated transport. Doerfler R, Yerneni S, LoPresti S, Chaudhary N, Newby A, Melamed JR, Malaney A, Whitehead KA FASEB journal : official publication of the Federation of American Societies for Experimental Biology 39835705 FASEB J 2025 Jan 31 https://www.ncbi.nlm.nih.gov/pubmed/39835705
Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability. Lamson NG, Berger A, Fein KC, Whitehead KA Nature biomedical engineering 31686002 Nat Biomed Eng 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31686002
The Effect of Infant Gastric Digestion on Human Maternal Milk Cells. Doerfler R, Melamed JR, Whitehead KA Molecular nutrition & food research 35984112 Mol Nutr Food Res 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/35984112
Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery. Melamed JR, Hajj KA, Chaudhary N, Strelkova D, Arral ML, Pardi N, Alameh MG, Miller JB, Farbiak L, Siegwart DJ, Weissman D, Whitehead KA Journal of controlled release : official journal of the Controlled Release Society 34801660 J Control Release 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34801660
The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology. Gleeson JP, Fein KC, Chaudhary N, Doerfler R, Newby AN, Whitehead KA International journal of pharmaceutics 33249250 Int J Pharm 2021 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/33249250
Enhanced epigenetic modulation via mRNA-encapsulated lipid nanoparticles enables targeted anti-inflammatory control. Mokhtari T, Taheri MN, Akhlaghi S, Aryannejad A, Xiang Y, Mahajan V, Keshavarz K, Kiani A, LoPresti S, LeGraw R, Whitehead KA, Kiani S bioRxiv : the preprint server for biology 40060445 bioRxiv 2025 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/40060445
Characterization and comparison of human and mouse milk cells. Doerfler R, Yerneni S, Newby A, Chaudhary N, Shu A, Fein K, Hofstatter Azambuja J, Whitehead KA PloS one 38295101 PLoS One 2024 https://www.ncbi.nlm.nih.gov/pubmed/38295101
Heritability of Childhood Music Engagement and Associations with Language and Executive Function: Insights from the Adolescent Brain Cognitive Development (ABCD) Study. Gustavson DE, Nayak S, Coleman PL, Iversen JR, Lense MD, Gordon RL, Maes HH Behavior genetics 36757558 Behav Genet 2023 May https://www.ncbi.nlm.nih.gov/pubmed/36757558
The case for treatment fidelity in active music interventions: why and how. Wiens N, Gordon RL Annals of the New York Academy of Sciences 29727027 Ann N Y Acad Sci 2018 May 4 https://www.ncbi.nlm.nih.gov/pubmed/29727027
Infants' neural speech discrimination predicts individual differences in grammar ability at 6 years of age and their risk of developing speech-language disorders. Zhao TC, Boorom O, Kuhl PK, Gordon R Developmental cognitive neuroscience 33823366 Dev Cogn Neurosci 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33823366
Does rhythmic priming improve grammatical processing in Hungarian-speaking children with and without developmental language disorder? Ladányi E, Lukács Á, Gervain J Developmental science 34060171 Dev Sci 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34060171
Synaptic processes and immune-related pathways implicated in Tourette syndrome. Tsetsos F, Yu D, Sul JH, Huang AY, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau GA, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados MA, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Wagner M, Knowles JA, Jeremy Willsey A, Tischfield JA, Heiman GA, Cox NJ, Freimer NB, Neale BM, Davis LK, Coppola G, Mathews CA, Scharf JM, Paschou P, Tourette Association of America International Consortium for Genetics, Barr CL, Batterson JR, Berlin C, Budman CL, Cath DC, Coppola G, Cox NJ, Darrow S, Davis LK, Dion Y, Freimer NB, Grados MA, Greenberg E, Hirschtritt ME, Huang AY, Illmann C, King RA, Kurlan R, Leckman JF, Lyon GJ, Malaty IA, Mathews CA, McMahon WM, Neale BM, Okun MS, Osiecki L, Robertson MM, Rouleau GA, Sandor P, Scharf JM, Singer HS, Smit JH, Sul JH, Yu D, Gilles de la Tourette GWAS Replication Initiative, Aschauer HAH, Barta C, Budman CL, Cath DC, Depienne C, Hartmann A, Hebebrand J, Konstantinidis A, Mathews CA, Müller-Vahl K, Nagy P, Nöthen MM, Paschou P, Rizzo R, Rouleau GA, Sandor P, Scharf JM, Schlögelhofer M, Stamenkovic M, Stuhrmann M, Tsetsos F, Tarnok Z, Wolanczyk T, Worbe Y, Tourette International Collaborative Genetics Study, Brown L, Cheon KA, Coffey BJ, Dietrich A, Fernandez TV, Garcia-Delgar B, Gilbert D, Grice DE, Hagstrøm J, Hedderly T, Heiman GA, Heyman I, Hoekstra PJ, Huyser C, Kim YK, Kim YS, King RA, Koh YJ, Kook S, Kuperman S, Leventhal BL, Madruga-Garrido M, Mir P, Morer A, Münchau A, Plessen KJ, Roessner V, Shin EY, Song DH, Song J, Tischfield JA, Willsey AJ, Zinner S, Psychiatric Genomics Consortium Tourette Syndrome Working Group, Aschauer H, Barr CL, Barta C, Batterson JR, Berlin C, Brown L, Budman CL, Cath DC, Coffey BJ, Coppola G, Cox NJ, Darrow S, Davis LK, Depienne C, Dietrich A, Dion Y, Fernandez T, Freimer NB, Gilbert D, Grados MA, Greenberg E, Hartmann A, Hebebrand J, Heiman G, Hirschtritt ME, Hoekstra P, Huang AY, Illmann C, Jankovic J, King RA, Kuperman S, Lee PC, Lyon GJ, Malaty IA, Mathews CA, McMahon WM, Müller-Vahl K, Nagy P, Neale BM, Nöthen MM, Okun MS, Osiecki L, Paschou P, Rizzo R, Robertson MM, Rouleau GA, Sandor P, Scharf JM, Schlögelhofer M, Singer HS, Stamenkovic M, Stuhrmann M, Sul JH, Tarnok Z, Tischfield J, Tsetsos F, Willsey AJ, Woods D, Worbe Y, Yu D, Zinner S Translational psychiatry 33462189 Transl Psychiatry 2021 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/33462189
A neurodevelopmental disorders perspective into music, social attention, and social bonding. Kasdan A, Gordon RL, Lense MD The Behavioral and brain sciences 34588066 Behav Brain Sci 2021 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/34588066
Identifying a brain network for musical rhythm: A functional neuroimaging meta-analysis and systematic review. Kasdan AV, Burgess AN, Pizzagalli F, Scartozzi A, Chern A, Kotz SA, Wilson SM, Gordon RL Neuroscience and biobehavioral reviews 35259422 Neurosci Biobehav Rev 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35259422
The shared genetic architecture and evolution of human language and musical rhythm. Alagöz G, Eising E, Mekki Y, Bignardi G, Fontanillas P, 23andMe Research Team, Nivard MG, Luciano M, Cox NJ, Fisher SE, Gordon RL bioRxiv : the preprint server for biology 37961248 bioRxiv 2023 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/37961248
Linking the genomic signatures of human beat synchronization and learned song in birds. Gordon RL, Ravignani A, Hyland Bruno J, Robinson CM, Scartozzi A, Embalabala R, Niarchou M, 23andMe Research Team, Cox NJ, Creanza N Philosophical transactions of the Royal Society of London. Series B, Biological sciences 34420388 Philos Trans R Soc Lond B Biol Sci 2021 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/34420388
Medical phenome of musicians: an investigation of health records collected on 9803 musically active individuals. Niarchou M, Lin GT, Lense MD, Gordon RL, Davis LK Annals of the New York Academy of Sciences 34414577 Ann N Y Acad Sci 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34414577
The Latent Genetic Structure of Impulsivity and Its Relation to Internalizing Psychopathology. Gustavson DE, Friedman NP, Fontanillas P, Elson SL, 23andMe Research Team, Palmer AA, Sanchez-Roige S Psychological science 32716714 Psychol Sci 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32716714
You got rhythm, or more: The multidimensionality of rhythmic abilities. Fiveash A, Bella SD, Bigand E, Gordon RL, Tillmann B Attention, perception & psychophysics 35437703 Atten Percept Psychophys 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35437703
Musical instrument engagement in adolescence predicts verbal ability 4 years later: A twin and adoption study. Gustavson DE, Friedman NP, Stallings MC, Reynolds CA, Coon H, Corley RP, Hewitt JK, Gordon RL Developmental psychology 34914455 Dev Psychol 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34914455
Neurophysiological Correlates of Dynamic Beat Tracking in Individuals With Williams Syndrome. Kasdan A, Gordon RL, Lense MD Biological psychiatry. Cognitive neuroscience and neuroimaging 33419711 Biol Psychiatry Cogn Neurosci Neuroimaging 2022 Nov https://www.ncbi.nlm.nih.gov/pubmed/33419711
Processing rhythm in speech and music: Shared mechanisms and implications for developmental speech and language disorders. Fiveash A, Bedoin N, Gordon RL, Tillmann B Neuropsychology 34435803 Neuropsychology 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34435803
Regular rhythmic primes improve sentence repetition in children with developmental language disorder. Fiveash A, Ladányi E, Camici J, Chidiac K, Bush CT, Canette LH, Bedoin N, Gordon RL, Tillmann B NPJ science of learning 37429839 NPJ Sci Learn 2023 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/37429839
Individual differences in neural markers of beat processing relate to spoken grammar skills in six-year-old children. Persici V, Blain SD, Iversen JR, Key AP, Kotz SA, Devin McAuley J, Gordon RL Brain and language 37994830 Brain Lang 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37994830
Exploring the genetics of rhythmic perception and musical engagement in the Vanderbilt Online Musicality Study. Gustavson DE, Coleman PL, Wang Y, Nitin R, Petty LE, Bush CT, Mosing MA, Wesseldijk LW, Ullén F, 23 and Me Research Team, Below JE, Cox NJ, Gordon RL Annals of the New York Academy of Sciences 36718543 Ann N Y Acad Sci 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/36718543
The Musical Abilities, Pleiotropy, Language, and Environment (MAPLE) Framework for Understanding Musicality-Language Links Across the Lifespan. Nayak S, Coleman PL, Ladányi E, Nitin R, Gustavson DE, Fisher SE, Magne CL, Gordon RL Neurobiology of language (Cambridge, Mass.) 36742012 Neurobiol Lang (Camb) 2022 https://www.ncbi.nlm.nih.gov/pubmed/36742012
The Neural Correlates of Spontaneous Beat Processing and Its Relationship with Music-Related Characteristics of the Individual. Scartozzi AC, Wang Y, Bush CT, Kasdan AV, Fram NR, Woynaroski T, Lense MD, Gordon RL, Ladányi E eNeuro 39401929 eNeuro 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/39401929
Interprofessional education of the next generation of musician-scientists through music cognition research training: An innovative platform for health professions and biomedical research. Gordon RL, Lense MD Music and medicine 33603955 Music Med 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/33603955
Pushing the Envelope: Developments in Neural Entrainment to Speech and the Biological Underpinnings of Prosody Perception. Myers BR, Lense MD, Gordon RL Brain sciences 30909454 Brain Sci 2019 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/30909454
New evidence of a rhythmic priming effect that enhances grammaticality judgments in children. Chern A, Tillmann B, Vaughan C, Gordon RL Journal of experimental child psychology 29778278 J Exp Child Psychol 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/29778278
Genome-wide association study of musical beat synchronization demonstrates high polygenicity. Niarchou M, Gustavson DE, Sathirapongsasuti JF, Anglada-Tort M, Eising E, Bell E, McArthur E, Straub P, 23andMe Research Team, McAuley JD, Capra JA, Ullén F, Creanza N, Mosing MA, Hinds DA, Davis LK, Jacoby N, Gordon RL Nature human behaviour 35710621 Nat Hum Behav 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35710621
Exploring individual differences in musical rhythm and grammar skills in school-aged children with typically developing language. Nitin R, Gustavson DE, Aaron AS, Boorom OA, Bush CT, Wiens N, Vaughan C, Persici V, Blain SD, Soman U, Hambrick DZ, Camarata SM, McAuley JD, Gordon RL Scientific reports 36750727 Sci Rep 2023 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/36750727
Using a polygenic score in a family design to understand genetic influences on musicality. Wesseldijk LW, Abdellaoui A, Gordon RL, 23andMe Research Team, Ullén F, Mosing MA Scientific reports 36038631 Sci Rep 2022 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/36038631
Mental health and music engagement: review, framework, and guidelines for future studies. Gustavson DE, Coleman PL, Iversen JR, Maes HH, Gordon RL, Lense MD Translational psychiatry 34226495 Transl Psychiatry 2021 Jun 22 https://www.ncbi.nlm.nih.gov/pubmed/34226495
Rhythm and timing as vulnerabilities in neurodevelopmental disorders. Lense MD, Ladányi E, Rabinowitch TC, Trainor L, Gordon R Philosophical transactions of the Royal Society of London. Series B, Biological sciences 34420385 Philos Trans R Soc Lond B Biol Sci 2021 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/34420385
Is atypical rhythm a risk factor for developmental speech and language disorders? Ladányi E, Persici V, Fiveash A, Tillmann B, Gordon RL Wiley interdisciplinary reviews. Cognitive science 32244259 Wiley Interdiscip Rev Cogn Sci 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32244259
Genetic and Environmental Influences on Semantic Verbal Fluency Across Midlife and Later Life. Gustavson DE, Panizzon MS, Kremen WS, Reynolds CA, Pahlen S, Nygaard M, Wod M, Catts VS, Lee T, Gatz M, Franz CE, IGEMS Consortium Behavior genetics 33547998 Behav Genet 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33547998
Elevated Polygenic Burden for Autism Spectrum Disorder Is Associated With the Broad Autism Phenotype in Mothers of Individuals With Autism Spectrum Disorder. Nayar K, Sealock JM, Maltman N, Bush L, Cook EH, Davis LK, Losh M Biological psychiatry 33229037 Biol Psychiatry 2021 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/33229037
Confronting ethical and social issues related to the genetics of musicality. Gordon RL, Martschenko DO, Nayak S, Niarchou M, Morrison MD, Bell E, Jacoby N, Davis LK Annals of the New York Academy of Sciences 36851882 Ann N Y Acad Sci 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36851882
The shared genetic architecture and evolution of human language and musical rhythm. Alagöz G, Eising E, Mekki Y, Bignardi G, Fontanillas P, 23andMe Research Team, Nivard MG, Luciano M, Cox NJ, Fisher SE, Gordon RL Nature human behaviour 39572686 Nat Hum Behav 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39572686
Targeted Rediscovery and Biosynthesis of the Farnesyl-Transferase Inhibitor Pepticinnamin E. Santa Maria KC, Chan AN, O'Neill EM, Li B Chembiochem : a European journal of chemical biology 30694017 Chembiochem 2019 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/30694017
Chemoproteomics Reveals Disruption of Metal Homeostasis and Metalloproteins by the Antibiotic Holomycin. Chan AN, Chen X, Falco JA, Bak DW, Weerapana E, Li B ACS chemical biology 37561838 ACS Chem Biol 2023 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/37561838
A Permissive Amide N-Methyltransferase for Dithiolopyrrolones. Chen X, Johnson RM, Li B ACS catalysis 38106463 ACS Catal 2023 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/38106463
In Vitro Reconstitution Reveals a Central Role for the N-Oxygenase PvfB in (Dihydro)pyrazine-N-oxide and Valdiazen Biosynthesis. Morgan GL, Li B Angewandte Chemie (International ed. in English) 32662921 Angew Chem Int Ed Engl 2020 Nov 23 https://www.ncbi.nlm.nih.gov/pubmed/32662921
Enzymatic Synthesis of Diverse Heterocycles by a Noncanonical Nonribosomal Peptide Synthetase. Morgan GL, Li K, Crawford DM, Aubé J, Li B ACS chemical biology 34767712 ACS Chem Biol 2021 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/34767712
Pseudomonas Virulence Factor Pathway Synthesizes Autoinducers That Regulate the Secretome of a Pathogen. Kretsch AM, Morgan GL, Acken KA, Barr SA, Li B ACS chemical biology 33595276 ACS Chem Biol 2021 Mar 19 https://www.ncbi.nlm.nih.gov/pubmed/33595276
Specificity of Nonribosomal Peptide Synthetases in the Biosynthesis of the Pseudomonas virulence factor. Morgan GL, Kretsch AM, Santa Maria KC, Weeks SJ, Li B Biochemistry 31243997 Biochemistry 2019 Dec 31 https://www.ncbi.nlm.nih.gov/pubmed/31243997
Pseudomonas virulence factor controls expression of virulence genes in Pseudomonas entomophila. Acken KA, Li B PloS one 37200397 PLoS One 2023 https://www.ncbi.nlm.nih.gov/pubmed/37200397
Activation of Dithiolopyrrolone Antibiotics by Cellular Reductants. Steiner OM, Johnson RA, Chen X, Simke WC, Li B Biochemistry 39665630 Biochemistry 2025 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/39665630
Discovery and Biosynthesis of Azabicyclene, a Conserved Nonribosomal Peptide in Pseudomonas aeruginosa. Patteson JB, Lescallette AR, Li B Organic letters 31247735 Org Lett 2019 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/31247735
Biosynthesis of fluopsin C, a copper-containing antibiotic from Pseudomonas aeruginosa. Patteson JB, Putz AT, Tao L, Simke WC, Bryant LH 3rd, Britt RD, Li B Science (New York, N.Y.) 34793213 Science 2021 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/34793213
Inhibition of Isoleucyl-tRNA Synthetase by the Hybrid Antibiotic Thiomarinol. Johnson RA, Chan AN, Ward RD, McGlade CA, Hatfield BM, Peters JM, Li B Journal of the American Chemical Society 34342433 J Am Chem Soc 2021 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/34342433
Discovery of (Dihydro)pyrazine N-Oxides via Genome Mining in Pseudomonas. Kretsch AM, Morgan GL, Tyrrell J, Mevers E, Vallet-Gély I, Li B Organic letters 30073838 Org Lett 2018 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/30073838
Purification and characterization of tomato arginine decarboxylase and its inhibition by the bacterial small molecule phevamine A. Guo Q, Chen X, Li B Protein expression and purification 37348664 Protein Expr Purif 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/37348664
The Hybrid Antibiotic Thiomarinol A Overcomes Intrinsic Resistance in Escherichia coli Using a Privileged Dithiolopyrrolone Moiety. Johnson RM, Li K, Chen X, Morgan GL, Aubé J, Li B ACS infectious diseases 38226592 ACS Infect Dis 2024 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/38226592
"Rho"ing a Cellular Boat with Rearward Membrane Flow. Bell GRR, Collins SR Developmental cell 29974859 Dev Cell 2018 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/29974859
Directional reorientation of migrating neutrophils is limited by suppression of receptor input signaling at the cell rear through myosin II activity. Hadjitheodorou A, Bell GRR, Ellett F, Shastry S, Irimia D, Collins SR, Theriot JA Nature communications 34785640 Nat Commun 2021 Nov 16 https://www.ncbi.nlm.nih.gov/pubmed/34785640
Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens. Haney MS, Bohlen CJ, Morgens DW, Ousey JA, Barkal AA, Tsui CK, Ego BK, Levin R, Kamber RA, Collins H, Tucker A, Li A, Vorselen D, Labitigan L, Crane E, Boyle E, Jiang L, Chan J, Rincón E, Greenleaf WJ, Li B, Snyder MP, Weissman IL, Theriot JA, Collins SR, Barres BA, Bassik MC Nature genetics 30397336 Nat Genet 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30397336
Optimized iLID Membrane Anchors for Local Optogenetic Protein Recruitment. Natwick DE, Collins SR ACS synthetic biology 33843200 ACS Synth Biol 2021 May 21 https://www.ncbi.nlm.nih.gov/pubmed/33843200
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes. Liou MJ, Miller BM, Litvak Y, Nguyen H, Natwick DE, Savage HP, Rixon JA, Mahan SP, Hiyoshi H, Rogers AWL, Velazquez EM, Butler BP, Collins SR, McSorley SJ, Harshey RM, Byndloss MX, Simon SI, Bäumler AJ Cell host & microbe 35568027 Cell Host Microbe 2022 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/35568027
Neutrophil-like cells derived from the HL-60 cell-line as a genetically-tractable model for neutrophil degranulation. Bhakta SB, Lundgren SM, Sesti BN, Flores BA, Akdogan E, Collins SR, Mercer F PloS one 38324578 PLoS One 2024 https://www.ncbi.nlm.nih.gov/pubmed/38324578
Whole-genome screens reveal regulators of differentiation state and context-dependent migration in human neutrophils. Belliveau NM, Footer MJ, Akdoǧan E, van Loon AP, Collins SR, Theriot JA Nature communications 37723145 Nat Commun 2023 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/37723145
Decoding GEFs of animated cells. Natwick DE, Collins SR Nature chemical biology 32694631 Nat Chem Biol 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32694631
A map of gene expression in neutrophil-like cell lines. Rincón E, Rocha-Gregg BL, Collins SR BMC genomics 30068296 BMC Genomics 2018 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/30068296
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors. Lundgren SM, Rocha-Gregg BL, Akdoğan E, Mysore MN, Hayes S, Collins SR Science signaling 37788324 Sci Signal 2023 Oct 3 https://www.ncbi.nlm.nih.gov/pubmed/37788324
A complex of Wnt/planar cell polarity signaling components Vangl1 and Fzd7 drives glioblastoma multiforme malignant properties. Dreyer CA, VanderVorst K, Natwick D, Bell G, Sood P, Hernandez M, Angelastro JM, Collins SR, Carraway KL 3rd Cancer letters 37336284 Cancer Lett 2023 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/37336284
Flagella-driven motility is a target of human Paneth cell defensin activity. Akahoshi DT, Natwick DE, Yuan W, Lu W, Collins SR, Bevins CL PLoS pathogens 36821624 PLoS Pathog 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/36821624
Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing. Bell GRR, Rincón E, Akdoğan E, Collins SR Nature communications 34785668 Nat Commun 2021 Nov 16 https://www.ncbi.nlm.nih.gov/pubmed/34785668
Parallel High-Resolution Imaging of Leukocyte Chemotaxis Under Agarose with Rho-Family GTPase Biosensors. Bell GRR, Natwick DE, Collins SR Methods in molecular biology (Clifton, N.J.) 30062406 Methods Mol Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30062406
Leading edge competition promotes context-dependent responses to receptor inputs to resolve directional dilemmas in neutrophil migration. Hadjitheodorou A, Bell GRR, Ellett F, Irimia D, Tibshirani R, Collins SR, Theriot JA Cell systems 36827986 Cell Syst 2023 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/36827986
Vangl-dependent Wnt/planar cell polarity signaling mediates collective breast carcinoma motility and distant metastasis. VanderVorst K, Dreyer CA, Hatakeyama J, Bell GRR, Learn JA, Berg AL, Hernandez M, Lee H, Collins SR, Carraway KL 3rd Breast cancer research : BCR 37147680 Breast Cancer Res 2023 May 5 https://www.ncbi.nlm.nih.gov/pubmed/37147680
Modeling Subcellular Protein Recruitment Dynamics for Synthetic Biology. Badu-Nkansah KA, Sernas D, Natwick DE, Collins SR Methods in molecular biology (Clifton, N.J.) 36227545 Methods Mol Biol 2023 https://www.ncbi.nlm.nih.gov/pubmed/36227545
Predictive modeling reveals that higher-order cooperativity drives transcriptional repression in a synthetic developmental enhancer. Kim YJ, Rhee K, Liu J, Jeammet S, Turner MA, Small SJ, Garcia HG eLife 36503705 Elife 2022 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/36503705
Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila. Child MB 6th, Bateman JR, Jahangiri A, Reimer A, Lammers NC, Sabouni N, Villamarin D, McKenzie-Smith GC, Johnson JE, Jost D, Garcia HG eLife 34100718 Elife 2021 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/34100718
Quantitative imaging of RNA polymerase II activity in plants reveals the single-cell basis of tissue-wide transcriptional dynamics. Alamos S, Reimer A, Niyogi KK, Garcia HG Nature plants 34373604 Nat Plants 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34373604
Kinetic sculpting of the seven stripes of the Drosophila even-skipped gene. Berrocal A, Lammers NC, Garcia HG, Eisen MB eLife 33300492 Elife 2020 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/33300492
Minimal synthetic enhancers reveal control of the probability of transcriptional engagement and its timing by a morphogen gradient. Alamos S, Reimer A, Westrum C, Turner MA, Talledo P, Zhao J, Luu E, Garcia HG Cell systems 36696901 Cell Syst 2023 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/36696901
Single cell biology-a Keystone Symposia report. Cable J, Elowitz MB, Domingos AI, Habib N, Itzkovitz S, Hamidzada H, Balzer MS, Yanai I, Liberali P, Whited J, Streets A, Cai L, Stergachis AB, Hong CKY, Keren L, Guilliams M, Alon U, Shalek AK, Hamel R, Pfau SJ, Raj A, Quake SR, Zhang NR, Fan J, Trapnell C, Wang B, Greenwald NF, Vento-Tormo R, Santos SDM, Spencer SL, Garcia HG, Arekatla G, Gaiti F, Arbel-Goren R, Rulands S, Junker JP, Klein AM, Morris SA, Murray JI, Galloway KE, Ratz M, Romeike M Annals of the New York Academy of Sciences 34605044 Ann N Y Acad Sci 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34605044
Quantitative dissection of transcription in development yields evidence for transcription-factor-driven chromatin accessibility. Eck E, Liu J, Kazemzadeh-Atoufi M, Ghoreishi S, Blythe SA, Garcia HG eLife 33074101 Elife 2020 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/33074101
Genetically Encoded Fluorescent Biosensor for Rapid Detection of Protein Expression. Eason MG, Pandelieva AT, Mayer MM, Khan ST, Garcia HG, Chica RA ACS synthetic biology 33044070 ACS Synth Biol 2020 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/33044070
Lighting up the central dogma for predictive developmental biology. Garcia HG, Berrocal A, Kim YJ, Martini G, Zhao J Current topics in developmental biology 32143740 Curr Top Dev Biol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32143740
A matter of time: Using dynamics and theory to uncover mechanisms of transcriptional bursting. Lammers NC, Kim YJ, Zhao J, Garcia HG Current opinion in cell biology 33242838 Curr Opin Cell Biol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33242838
The Drosophila Pioneer Factor Zelda Modulates the Nuclear Microenvironment of a Dorsal Target Enhancer to Potentiate Transcriptional Output. Yamada S, Whitney PH, Huang SK, Eck EC, Garcia HG, Rushlow CA Current biology : CB 30982648 Curr Biol 2019 Apr 22 https://www.ncbi.nlm.nih.gov/pubmed/30982648
Competing constraints shape the nonequilibrium limits of cellular decision-making. Lammers NC, Flamholz AI, Garcia HG Proceedings of the National Academy of Sciences of the United States of America 36862689 Proc Natl Acad Sci U S A 2023 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/36862689
Single Molecule Imaging in Live Embryos Using Lattice Light-Sheet Microscopy. Mir M, Reimer A, Stadler M, Tangara A, Hansen AS, Hockemeyer D, Eisen MB, Garcia H, Darzacq X Methods in molecular biology (Clifton, N.J.) 29956254 Methods Mol Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/29956254
LlamaTags: A Versatile Tool to Image Transcription Factor Dynamics in Live Embryos. Bothma JP, Norstad MR, Alamos S, Garcia HG Cell 29754814 Cell 2018 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/29754814
Real-time single-cell characterization of the eukaryotic transcription cycle reveals correlations between RNA initiation, elongation, and cleavage. Liu J, Hansen D, Eck E, Kim YJ, Turner M, Alamos S, Garcia HG PLoS computational biology 34003867 PLoS Comput Biol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/34003867
Figure 1 Theory Meets Figure 2 Experiments in the Study of Gene Expression. Phillips R, Belliveau NM, Chure G, Garcia HG, Razo-Mejia M, Scholes C Annual review of biophysics 31084583 Annu Rev Biophys 2019 May 6 https://www.ncbi.nlm.nih.gov/pubmed/31084583
Multimodal transcriptional control of pattern formation in embryonic development. Lammers NC, Galstyan V, Reimer A, Medin SA, Wiggins CH, Garcia HG Proceedings of the National Academy of Sciences of the United States of America 31882445 Proc Natl Acad Sci U S A 2020 Jan 14 https://www.ncbi.nlm.nih.gov/pubmed/31882445
Chromatin Changes in Phytochrome Interacting Factor-Regulated Genes Parallel Their Rapid Transcriptional Response to Light. González-Grandío E, Álamos S, Zhang Y, Dalton-Roesler J, Niyogi KK, García HG, Quail PH Frontiers in plant science 35251080 Front Plant Sci 2022 https://www.ncbi.nlm.nih.gov/pubmed/35251080
Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis. Shami AN, Zheng X, Munyoki SK, Ma Q, Manske GL, Green CD, Sukhwani M, Orwig KE, Li JZ, Hammoud SS Developmental cell 32504559 Dev Cell 2020 Aug 24 https://www.ncbi.nlm.nih.gov/pubmed/32504559
Proteomic analysis of human sperm reveals changes in protamine 1 phosphorylation in men with infertility. Schon SB, Moritz L, Rabbani M, Meguid J, Juliano BR, Ruotolo BT, Aston K, Hammoud SS F&S science 38065301 F S Sci 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38065301
Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells. Grill S, Bisht K, Tesmer VM, Shami AN, Hammoud SS, Nandakumar J Cell reports 31216472 Cell Rep 2019 Jun 18 https://www.ncbi.nlm.nih.gov/pubmed/31216472
A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq. Green CD, Ma Q, Manske GL, Shami AN, Zheng X, Marini S, Moritz L, Sultan C, Gurczynski SJ, Moore BB, Tallquist MD, Li JZ, Hammoud SS Developmental cell 30146481 Dev Cell 2018 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/30146481
Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline. Graniel JV, Bisht K, Friedman A, White J, Perkey E, Vanderbeck A, Moroz A, Carrington LJ, Brandstadter JD, Allen F, Shami AN, Thomas P, Crayton A, Manzor M, Mychalowych A, Chase J, Hammoud SS, Keegan CE, Maillard I, Nandakumar J Life science alliance 34645668 Life Sci Alliance 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34645668
Decoding the Spermatogenesis Program: New Insights from Transcriptomic Analyses. Rabbani M, Zheng X, Manske GL, Vargo A, Shami AN, Li JZ, Hammoud SS Annual review of genetics 36070560 Annu Rev Genet 2022 Nov 30 https://www.ncbi.nlm.nih.gov/pubmed/36070560
TCF21(+) mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice. Shen YC, Shami AN, Moritz L, Larose H, Manske GL, Ma Q, Zheng X, Sukhwani M, Czerwinski M, Sultan C, Chen H, Gurczynski SJ, Spence JR, Orwig KE, Tallquist M, Li JZ, Hammoud SS Nature communications 34162856 Nat Commun 2021 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/34162856
Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1. Moritz L, Schon SB, Rabbani M, Sheng Y, Agrawal R, Glass-Klaiber J, Sultan C, Camarillo JM, Clements J, Baldwin MR, Diehl AG, Boyle AP, O'Brien PJ, Ragunathan K, Hu YC, Kelleher NL, Nandakumar J, Li JZ, Orwig KE, Redding S, Hammoud SS Nature structural & molecular biology 37460896 Nat Struct Mol Biol 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37460896
Regulation of meiotic progression by Sertoli-cell androgen signaling. Larose H, Kent T, Ma Q, Shami AN, Harerimana N, Li JZ, Hammoud SS, Handel MA Molecular biology of the cell 33026960 Mol Biol Cell 2020 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/33026960
Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq. Ulrich ND, Shen YC, Ma Q, Yang K, Hannum DF, Jones A, Machlin J, Randolph JF Jr, Smith YR, Schon SB, Shikanov A, Marsh EE, Lieberman R, Gurczynski SJ, Moore BB, Li JZ, Hammoud S Developmental cell 35320732 Dev Cell 2022 Apr 11 https://www.ncbi.nlm.nih.gov/pubmed/35320732
The Art of Packaging the Sperm Genome: Molecular and Structural Basis of the Histone-To-Protamine Exchange. Moritz L, Hammoud SS Frontiers in endocrinology 35813619 Front Endocrinol (Lausanne) 2022 https://www.ncbi.nlm.nih.gov/pubmed/35813619
Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal women. Ulrich ND, Vargo A, Ma Q, Shen YC, Bazzano D, Hannum DF, Gurczynski SJ, Moore BB, Schon S, Lieberman R, Shikanov A, Marsh EE, Fazleabas A, Li JZ, Hammoud SS Proceedings of the National Academy of Sciences of the United States of America 39471215 Proc Natl Acad Sci U S A 2024 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/39471215
Asymmetric Histone Inheritance Regulates Differential Transcription Re-initiation and Cell Fate Decisions in Mouse Olfactory Horizontal Basal Cells. Ma B, Yang G, Yao J, Wu C, Vega JP, Manske G, Hammoud SS, Sinha S, Singh A, Zhao H, Chen X bioRxiv : the preprint server for biology 40093102 bioRxiv 2025 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/40093102
Natural language processing: put your model where your mouth is. Haggerty RA, Purvis JE Molecular systems biology 29254950 Mol Syst Biol 2017 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/29254950
Autophagy regulates the localization and degradation of p16(INK4a). Coryell PR, Goraya SK, Griffin KA, Redick MA, Sisk SR, Purvis JE Aging cell 32662244 Aging Cell 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32662244
A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics. Burclaff J, Bliton RJ, Breau KA, Ok MT, Gomez-Martinez I, Ranek JS, Bhatt AP, Purvis JE, Woosley JT, Magness ST Cellular and molecular gastroenterology and hepatology 35176508 Cell Mol Gastroenterol Hepatol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35176508
Inheritance of OCT4 predetermines fate choice in human embryonic stem cells. Wolff SC, Kedziora KM, Dumitru R, Dungee CD, Zikry TM, Beltran AS, Haggerty RA, Cheng J, Redick MA, Purvis JE Molecular systems biology 30177503 Mol Syst Biol 2018 Sep 3 https://www.ncbi.nlm.nih.gov/pubmed/30177503
Orchestration of DNA Damage Checkpoint Dynamics across the Human Cell Cycle. Chao HX, Poovey CE, Privette AA, Grant GD, Chao HY, Cook JG, Purvis JE Cell systems 29102360 Cell Syst 2017 Nov 22 https://www.ncbi.nlm.nih.gov/pubmed/29102360
Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2. Enrico TP, Stallaert W, Wick ET, Ngoi P, Wang X, Rubin SM, Brown NG, Purvis JE, Emanuele MJ eLife 34851822 Elife 2021 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/34851822
Accurate delineation of cell cycle phase transitions in living cells with PIP-FUCCI. Grant GD, Kedziora KM, Limas JC, Cook JG, Purvis JE Cell cycle (Georgetown, Tex.) 30421640 Cell Cycle 2018 https://www.ncbi.nlm.nih.gov/pubmed/30421640
The consequences of differential origin licensing dynamics in distinct chromatin environments. Mei L, Kedziora KM, Song EA, Purvis JE, Cook JG Nucleic acids research 35079814 Nucleic Acids Res 2022 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/35079814
Integrating temporal single-cell gene expression modalities for trajectory inference and disease prediction. Ranek JS, Stanley N, Purvis JE Genome biology 36064614 Genome Biol 2022 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/36064614
Bistable switches as integrators and actuators during cell cycle progression. Stallaert W, Kedziora KM, Chao HX, Purvis JE FEBS letters 31566708 FEBS Lett 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31566708
The Cell Cycle Browser: An Interactive Tool for Visualizing, Simulating, and Perturbing Cell-Cycle Progression. Borland D, Yi H, Grant GD, Kedziora KM, Chao HX, Haggerty RA, Kumar J, Wolff SC, Cook JG, Purvis JE Cell systems 30077635 Cell Syst 2018 Aug 22 https://www.ncbi.nlm.nih.gov/pubmed/30077635
The structure of the human cell cycle. Stallaert W, Kedziora KM, Taylor CD, Zikry TM, Ranek JS, Sobon HK, Taylor SR, Young CL, Cook JG, Purvis JE Cell systems 35051372 Cell Syst 2022 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/35051372
The structure of the human cell cycle. Stallaert W, Kedziora KM, Taylor CD, Zikry TM, Ranek JS, Sobon HK, Taylor SR, Young CL, Cook JG, Purvis JE Cell systems 34800361 Cell Syst 2022 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/34800361
Inferring the structures of signaling motifs from paired dynamic traces of single cells. Haggerty RA, Purvis JE PLoS computational biology 33539338 PLoS Comput Biol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33539338
Chemical screen for epigenetic barriers to single allele activation of Oct4. Headley KM, Kedziora KM, Alejo A, Lai EZ, Purvis JE, Hathaway NA Stem cell research 31170660 Stem Cell Res 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31170660
Genetic determinants of cellular addiction to DNA polymerase theta. Feng W, Simpson DA, Carvajal-Garcia J, Price BA, Kumar RJ, Mose LE, Wood RD, Rashid N, Purvis JE, Parker JS, Ramsden DA, Gupta GP Nature communications 31537809 Nat Commun 2019 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/31537809
Evidence that the human cell cycle is a series of uncoupled, memoryless phases. Chao HX, Fakhreddin RI, Shimerov HK, Kedziora KM, Kumar RJ, Perez J, Limas JC, Grant GD, Cook JG, Gupta GP, Purvis JE Molecular systems biology 30886052 Mol Syst Biol 2019 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/30886052
Rapid DNA replication origin licensing protects stem cell pluripotency. Matson JP, Dumitru R, Coryell P, Baxley RM, Chen W, Twaroski K, Webber BR, Tolar J, Bielinsky AK, Purvis JE, Cook JG eLife 29148972 Elife 2017 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/29148972
Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency. Kumar RJ, Chao HX, Simpson DA, Feng W, Cho MG, Roberts VR, Sullivan AR, Shah SJ, Wozny AS, Fagan-Solis K, Kumar S, Luthman A, Ramsden DA, Purvis JE, Gupta GP NAR cancer 33385162 NAR Cancer 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33385162
Cost-effectiveness of expanding the capacity of opioid agonist treatment in Ukraine: dynamic modeling analysis. Morozova O, Crawford FW, Cohen T, Paltiel AD, Altice FL Addiction (Abingdon, England) 31478285 Addiction 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/31478285
Computational methods for birth-death processes. Crawford FW, Ho LST, Suchard MA Wiley interdisciplinary reviews. Computational statistics 29942419 Wiley Interdiscip Rev Comput Stat 2018 Mar-Apr https://www.ncbi.nlm.nih.gov/pubmed/29942419
Exposure, hazard, and survival analysis of diffusion on social networks. Wu J, Crawford FW, Kim DA, Stafford D, Christakis NA Statistics in medicine 29707798 Stat Med 2018 Jul 30 https://www.ncbi.nlm.nih.gov/pubmed/29707798
COVID-19 projections for reopening Connecticut. Crawford FW, Li ZR, Morozova O medRxiv : the preprint server for health sciences 32588003 medRxiv 2020 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/32588003
SARS-CoV-2 attack rate and population immunity in southern New England, March 2020 - May 2021. Tran TN, Wikle NB, Yang F, Inam H, Leighow S, Gentilesco B, Chan P, Albert E, Strong ER, Pritchard JR, Hanage WP, Hanks EM, Crawford FW, Boni MF medRxiv : the preprint server for health sciences 34909789 medRxiv 2021 Dec 7 https://www.ncbi.nlm.nih.gov/pubmed/34909789
Risk ratios for contagious outcomes. Morozova O, Cohen T, Crawford FW Journal of the Royal Society, Interface 29343627 J R Soc Interface 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29343627
Impact of close interpersonal contact on COVID-19 incidence: evidence from one year of mobile device data. Crawford FW, Jones SA, Cartter M, Dean SG, Warren JL, Li ZR, Barbieri J, Campbell J, Kenney P, Valleau T, Morozova O medRxiv : the preprint server for health sciences 33758869 medRxiv 2021 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/33758869
Identification of causal intervention effects under contagion. Cai X, Loh WW, Crawford FW Journal of causal inference 34676152 J Causal Inference 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/34676152
Dependence-Robust Confidence Intervals for Capture-Recapture Surveys. Sun J, Van Baelen L, Plettinckx E, Crawford FW Journal of survey statistics and methodology 37975066 J Surv Stat Methodol 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37975066
Estimating the Size of a Large Network and its Communities from a Random Sample. Chen L, Karbasi A, Crawford FW Advances in neural information processing systems 28867924 Adv Neural Inf Process Syst 2016 https://www.ncbi.nlm.nih.gov/pubmed/28867924
An Adaptive Approach to Locating Mobile HIV Testing Services. Gonsalves GS, Crawford FW, Cleary PD, Kaplan EH, Paltiel AD Medical decision making : an international journal of the Society for Medical Decision Making 28699382 Med Decis Making 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/28699382
Empirical evidence of recruitment bias in a network study of people who inject drugs. Zeng L, Li J, Crawford FW The American journal of drug and alcohol abuse 30896982 Am J Drug Alcohol Abuse 2019 https://www.ncbi.nlm.nih.gov/pubmed/30896982
Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel. Prunas O, Warren JL, Crawford FW, Gazit S, Patalon T, Weinberger DM, Pitzer VE Science (New York, N.Y.) 35084937 Science 2022 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/35084937
Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel. Prunas O, Warren JL, Crawford FW, Gazit S, Patalon T, Weinberger DM, Pitzer VE medRxiv : the preprint server for health sciences 34981074 medRxiv 2021 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/34981074
Interpretation of the Individual Effect Under Treatment Spillover. Crawford FW, Morozova O, Buchanan AL, Spiegelman D American journal of epidemiology 31094425 Am J Epidemiol 2019 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/31094425
Evaluating the Mediating Role of Recall of Intervention Knowledge in the Relationship Between a Peer-Driven Intervention and HIV Risk Behaviors Among People Who Inject Drugs. Aroke H, Buchanan A, Katenka N, Crawford FW, Lee T, Halloran ME, Latkin C AIDS and behavior 35932359 AIDS Behav 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/35932359
Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks. Dean NE, Gsell PS, Brookmeyer R, Crawford FW, Donnelly CA, Ellenberg SS, Fleming TR, Halloran ME, Horby P, Jaki T, Krause PR, Longini IM, Mulangu S, Muyembe-Tamfum JJ, Nason MC, Smith PG, Wang R, Henao-Restrepo AM, De Gruttola V The New England journal of medicine 32242365 N Engl J Med 2020 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/32242365
One year of modeling and forecasting COVID-19 transmission to support policymakers in Connecticut. Morozova O, Li ZR, Crawford FW medRxiv : the preprint server for health sciences 32587978 medRxiv 2021 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/32587978
Violence and Discrimination Against Men Who Have Sex With Men in Lebanon: The Role of International Displacement and Migration. Orr L, Shebl FM, Heimer R, Khoshnood K, Barbour R, Khouri D, Aaraj E, Mokhbat JE, Crawford FW Journal of interpersonal violence 31658847 J Interpers Violence 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/31658847
Estimates of people who injected drugs within the last 12 months in Belgium based on a capture-recapture and multiplier method. Plettinckx E, Crawford FW, Antoine J, Gremeaux L, Van Baelen L Drug and alcohol dependence 33310486 Drug Alcohol Depend 2021 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/33310486
Transmission Modeling with Regression Adjustment for Analyzing Household-based Studies of Infectious Disease: Application to Tuberculosis. Crawford FW, Marx FM, Zelner J, Cohen T Epidemiology (Cambridge, Mass.) 31764276 Epidemiology 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/31764276
Estimating the early death toll of COVID-19 in the United States. Weinberger DM, Cohen T, Crawford FW, Mostashari F, Olson D, Pitzer VE, Reich NG, Russi M, Simonsen L, Watkins A, Viboud C medRxiv : the preprint server for health sciences 32511293 medRxiv 2020 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/32511293
Hidden population size estimation from respondent-driven sampling: a network approach. Crawford FW, Wu J, Heimer R Journal of the American Statistical Association 30828120 J Am Stat Assoc 2018 https://www.ncbi.nlm.nih.gov/pubmed/30828120
Predictors of Mortality within Prison and after Release among Persons Living with HIV in Indonesia. Culbert GJ, Crawford FW, Murni A, Waluyo A, Bazazi AR, Sahar J, Altice FL Research and reports in tropical medicine 29238241 Res Rep Trop Med 2017 https://www.ncbi.nlm.nih.gov/pubmed/29238241
HIV Risk, Prevalence, and Access to Care Among Men Who Have Sex with Men in Lebanon. Heimer R, Barbour R, Khouri D, Crawford FW, Shebl F, Aaraj E, Khoshnood K AIDS research and human retroviruses 28540733 AIDS Res Hum Retroviruses 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28540733
HIV Testing and awareness of HIV status among people who inject drugs in greater Kuala Lumpur, Malaysia. Bazazi AR, Vijay A, Crawford FW, Heimer R, Kamarulzaman A, Altice FL AIDS care 28803503 AIDS Care 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/28803503
Randomized controlled trials of biomarker targets. Erlendsdottir M, Crawford FW Clinical trials (London, England) 36373783 Clin Trials 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/36373783
Randomization for the susceptibility effect of an infectious disease intervention. Eck DJ, Morozova O, Crawford FW Journal of mathematical biology 36127558 J Math Biol 2022 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/36127558
Impact of close interpersonal contact on COVID-19 incidence: Evidence from 1 year of mobile device data. Crawford FW, Jones SA, Cartter M, Dean SG, Warren JL, Li ZR, Barbieri J, Campbell J, Kenney P, Valleau T, Morozova O Science advances 34995121 Sci Adv 2022 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/34995121
One year of modeling and forecasting COVID-19 transmission to support policymakers in Connecticut. Morozova O, Li ZR, Crawford FW Scientific reports 34642405 Sci Rep 2021 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/34642405
Suspected heroin-related overdoses incidents in Cincinnati, Ohio: A spatiotemporal analysis. Li ZR, Xie E, Crawford FW, Warren JL, McConnell K, Copple JT, Johnson T, Gonsalves GS PLoS medicine 31714940 PLoS Med 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31714940
Opioid Agonist Treatment and Improved Outcomes at Each Stage of the HIV Treatment Cascade in People Who Inject Drugs in Ukraine. Mazhnaya A, Marcus R, Bojko MJ, Zelenev A, Makarenko I, Pykalo I, Filippovych S, Dvoriak S, Altice FL Journal of acquired immune deficiency syndromes (1999) 30312275 J Acquir Immune Defic Syndr 2018 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/30312275
Estimating dose-specific cell division and apoptosis rates from chemo-sensitivity experiments. Liu Y, Crawford FW Scientific reports 29426887 Sci Rep 2018 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/29426887
Divergent estimates of HIV incidence among people who inject drugs in Ukraine. Morozova O, Booth RE, Dvoriak S, Dumchev K, Sazonova Y, Saliuk T, Crawford FW The International journal on drug policy 31405731 Int J Drug Policy 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31405731
Using sigLASSO to optimize cancer mutation signatures jointly with sampling likelihood. Li S, Crawford FW, Gerstein MB Nature communications 32681003 Nat Commun 2020 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/32681003
Dynamics of the HIV outbreak and response in Scott County, IN, USA, 2011-15: a modelling study. Gonsalves GS, Crawford FW The lancet. HIV 30220531 Lancet HIV 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30220531
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Quantifying and Engineering Mucus Adhesion of Probiotics. Mays ZJS, Chappell TC, Nair NU ACS synthetic biology 31909976 ACS Synth Biol 2020 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/31909976
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Synthetic biology in probiotic lactic acid bacteria: At the frontier of living therapeutics. Mays ZJ, Nair NU Current opinion in biotechnology 29550614 Curr Opin Biotechnol 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/29550614
Specific codons control cellular resources and fitness. Love AM, Nair NU Science advances 38381824 Sci Adv 2024 Feb 23 https://www.ncbi.nlm.nih.gov/pubmed/38381824
Towards universal synthetic heterotrophy using a metabolic coordinator. Sullivan SF, Shetty A, Bharadwaj T, Krishna N, Trivedi VD, Endalur Gopinarayanan V, Chappell TC, Sellers DM, Pravin Kumar R, Nair NU Metabolic engineering 37406763 Metab Eng 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37406763
A semi-synthetic regulon enables rapid growth of yeast on xylose. Endalur Gopinarayanan V, Nair NU Nature communications 29581426 Nat Commun 2018 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/29581426
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Towards creating an extended metabolic model (EMM) for E. coli using enzyme promiscuity prediction and metabolomics data. Amin SA, Chavez E, Porokhin V, Nair NU, Hassoun S Microbial cell factories 31196115 Microb Cell Fact 2019 Jun 13 https://www.ncbi.nlm.nih.gov/pubmed/31196115
Galactose to tagatose isomerization at moderate temperatures with high conversion and productivity. Bober JR, Nair NU Nature communications 31591402 Nat Commun 2019 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/31591402
Toward a genetic tool development pipeline for host-associated bacteria. Waller MC, Bober JR, Nair NU, Beisel CL Current opinion in microbiology 28624690 Curr Opin Microbiol 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28624690
Engineered lactobacilli display anti-biofilm and growth suppressing activities against Pseudomonas aeruginosa. Chappell TC, Nair NU NPJ biofilms and microbiomes 33127888 NPJ Biofilms Microbiomes 2020 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/33127888
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Characterization of a membrane enzymatic complex for heterologous production of poly-γ-glutamate in E. coli. Motta Nascimento B, Nair NU Metabolic engineering communications 32963960 Metab Eng Commun 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32963960
Pentose Metabolism in Saccharomyces cerevisiae: The Need to Engineer Global Regulatory Systems. Endalur Gopinarayanan V, Nair NU Biotechnology journal 30171750 Biotechnol J 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30171750
Establishing synthesis pathway-host compatibility via enzyme solubility. Amin SA, Endalur Gopinarayanan V, Nair NU, Hassoun S Biotechnology and bioengineering 30802311 Biotechnol Bioeng 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/30802311
Synthetic Biology Approaches to Engineer Probiotics and Members of the Human Microbiota for Biomedical Applications. Bober JR, Beisel CL, Nair NU Annual review of biomedical engineering 29528686 Annu Rev Biomed Eng 2018 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/29528686
Integration of metabolism and regulation reveals rapid adaptability to growth on non-native substrates. Trivedi VD, Sullivan SF, Choudhury D, Endalur Gopinarayanan V, Hart T, Nair NU Cell chemical biology 37421944 Cell Chem Biol 2023 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/37421944
In-depth Sequence-Function Characterization Reveals Multiple Pathways to Enhance Enzymatic Activity. Trivedi VD, Chappell TC, Krishna NB, Shetty A, Sigamani GG, Mohan K, Ramesh A, Pravin KR, Nair NU ACS catalysis 37325394 ACS Catal 2022 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/37325394
A Silk-Based Platform to Stabilize Phenylalanine Ammonia-lyase for Orally Administered Enzyme Replacement Therapy. d'Amone L, Trivedi VD, Nair NU, Omenetto FG Molecular pharmaceutics 35862031 Mol Pharm 2022 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/35862031
Synthetic biomarkers: a twenty-first century path to early cancer detection. Kwong GA, Ghosh S, Gamboa L, Patriotis C, Srivastava S, Bhatia SN Nature reviews. Cancer 34489588 Nat Rev Cancer 2021 Oct https://www.ncbi.nlm.nih.gov/pubmed/34489588
Protease circuits for processing biological information. Holt BA, Kwong GA Nature communications 33024117 Nat Commun 2020 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/33024117
AND-gated protease-activated nanosensors for programmable detection of anti-tumour immunity. Sivakumar A, Phuengkham H, Rajesh H, Mac QD, Rogers LC, Silva Trenkle AD, Bawage SS, Hincapie R, Li Z, Vainikos S, Lee I, Xue M, Qiu P, Finn MG, Kwong GA Nature nanotechnology 39753733 Nat Nanotechnol 2025 Mar https://www.ncbi.nlm.nih.gov/pubmed/39753733
Remote Control of Mammalian Cells with Heat-Triggered Gene Switches and Photothermal Pulse Trains. Miller IC, Gamboa Castro M, Maenza J, Weis JP, Kwong GA ACS synthetic biology 29579381 ACS Synth Biol 2018 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/29579381
In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles. Su FY, Zhao QH, Dahotre SN, Gamboa L, Bawage SS, Silva Trenkle AD, Zamat A, Phuengkham H, Ahmed R, Santangelo PJ, Kwong GA Science advances 35196075 Sci Adv 2022 Feb 25 https://www.ncbi.nlm.nih.gov/pubmed/35196075
Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity. Mac QD, Mathews DV, Kahla JA, Stoffers CM, Delmas OM, Holt BA, Adams AB, Kwong GA Nature biomedical engineering 30952979 Nat Biomed Eng 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30952979
Synthetic Antigen-Presenting Cells for Adoptive T Cell Therapy. Dahotre SN, Romanov AM, Su FY, Kwong GA Advanced therapeutics 34541300 Adv Ther (Weinh) 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34541300
Macrophage Sensors for Early Cancer Detection. Kwong GA Clinical chemistry 32040571 Clin Chem 2020 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/32040571
Synthetic immunity by remote control. Gamboa L, Zamat AH, Kwong GA Theranostics 32206114 Theranostics 2020 https://www.ncbi.nlm.nih.gov/pubmed/32206114
Deconvolving multiplexed protease signatures with substrate reduction and activity clustering. Zhuang Q, Holt BA, Kwong GA, Qiu P PLoS computational biology 31479443 PLoS Comput Biol 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31479443
Embracing enzyme promiscuity with activity-based compressed biosensing. Holt BA, Lim HS, Sivakumar A, Phuengkham H, Su M, Tuttle M, Xu Y, Liakakos H, Qiu P, Kwong GA Cell reports methods 36814844 Cell Rep Methods 2023 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/36814844
Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics. Holt BA, Mac QD, Kwong GA Journal of visualized experiments : JoVE 30059042 J Vis Exp 2018 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/30059042
Interfacing Biomaterials with Synthetic T Cell Immunity. Su FY, Mac QD, Sivakumar A, Kwong GA Advanced healthcare materials 33887123 Adv Healthc Mater 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/33887123
DNA-Barcoded pMHC Tetramers for Detection of Single Antigen-Specific T Cells by Digital PCR. Dahotre SN, Chang YM, Romanov AM, Kwong GA Analytical chemistry 30656939 Anal Chem 2019 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/30656939
Individually addressable and dynamic DNA gates for multiplexed cell sorting. Dahotre SN, Chang YM, Wieland A, Stammen SR, Kwong GA Proceedings of the National Academy of Sciences of the United States of America 29632190 Proc Natl Acad Sci U S A 2018 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/29632190
Heat-Triggered Remote Control of CRISPR-dCas9 for Tunable Transcriptional Modulation. Gamboa L, Phung EV, Li H, Meyers JP, Hart AC, Miller IC, Kwong GA ACS chemical biology 31904924 ACS Chem Biol 2020 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/31904924
Urinary detection of early responses to checkpoint blockade and of resistance to it via protease-cleaved antibody-conjugated sensors. Mac QD, Sivakumar A, Phuengkham H, Xu C, Bowen JR, Su FY, Stentz SZ, Sim H, Harris AM, Li TT, Qiu P, Kwong GA Nature biomedical engineering 35241815 Nat Biomed Eng 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35241815
Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control. Miller IC, Zamat A, Sun LK, Phuengkham H, Harris AM, Gamboa L, Yang J, Murad JP, Priceman SJ, Kwong GA Nature biomedical engineering 34385695 Nat Biomed Eng 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34385695
Dimensionless parameter predicts bacterial prodrug success. Holt BA, Tuttle M, Xu Y, Su M, Røise JJ, Wang X, Murthy N, Kwong GA Molecular systems biology 35005851 Mol Syst Biol 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/35005851
A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution. Packer JS, Zhu Q, Huynh C, Sivaramakrishnan P, Preston E, Dueck H, Stefanik D, Tan K, Trapnell C, Kim J, Waterston RH, Murray JI Science (New York, N.Y.) 31488706 Science 2019 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/31488706
Connect-seq to superimpose molecular on anatomical neural circuit maps. Hanchate NK, Lee EJ, Ellis A, Kondoh K, Kuang D, Basom R, Trapnell C, Buck LB Proceedings of the National Academy of Sciences of the United States of America 32034095 Proc Natl Acad Sci U S A 2020 Feb 25 https://www.ncbi.nlm.nih.gov/pubmed/32034095
Inferring Causal Gene Regulatory Networks from Coupled Single-Cell Expression Dynamics Using Scribe. Qiu X, Rahimzamani A, Wang L, Ren B, Mao Q, Durham T, McFaline-Figueroa JL, Saunders L, Trapnell C, Kannan S Cell systems 32135093 Cell Syst 2020 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/32135093
Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development. Sharon N, Vanderhooft J, Straubhaar J, Mueller J, Chawla R, Zhou Q, Engquist EN, Trapnell C, Gifford DK, Melton DA Cell reports 31116975 Cell Rep 2019 May 21 https://www.ncbi.nlm.nih.gov/pubmed/31116975
Thyroid hormone regulates distinct paths to maturation in pigment cell lineages. Saunders LM, Mishra AK, Aman AJ, Lewis VM, Toomey MB, Packer JS, Qiu X, McFaline-Figueroa JL, Corbo JC, Trapnell C, Parichy DM eLife 31140974 Elife 2019 May 29 https://www.ncbi.nlm.nih.gov/pubmed/31140974
The accessible chromatin landscape of the murine hippocampus at single-cell resolution. Sinnamon JR, Torkenczy KA, Linhoff MW, Vitak SA, Mulqueen RM, Pliner HA, Trapnell C, Steemers FJ, Mandel G, Adey AC Genome research 30936163 Genome Res 2019 May https://www.ncbi.nlm.nih.gov/pubmed/30936163
Reversed graph embedding resolves complex single-cell trajectories. Qiu X, Mao Q, Tang Y, Wang L, Chawla R, Pliner HA, Trapnell C Nature methods 28825705 Nat Methods 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28825705
A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. Gabrovsek L, Collins KB, Aggarwal S, Saunders LM, Lau HT, Suh D, Sancak Y, Trapnell C, Ong SE, Smith FD, Scott JD The Journal of biological chemistry 32482893 J Biol Chem 2020 Jul 31 https://www.ncbi.nlm.nih.gov/pubmed/32482893
Defining cell types and states with single-cell genomics. Trapnell C Genome research 26430159 Genome Res 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26430159
Comprehensive single-cell transcriptional profiling of a multicellular organism. Cao J, Packer JS, Ramani V, Cusanovich DA, Huynh C, Daza R, Qiu X, Lee C, Furlan SN, Steemers FJ, Adey A, Waterston RH, Trapnell C, Shendure J Science (New York, N.Y.) 28818938 Science 2017 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/28818938
Single-Cell Multi-omics: An Engine for New Quantitative Models of Gene Regulation. Packer J, Trapnell C Trends in genetics : TIG 30007833 Trends Genet 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30007833
Dynamics of Gene Expression in Single Root Cells of Arabidopsis thaliana. Jean-Baptiste K, McFaline-Figueroa JL, Alexandre CM, Dorrity MW, Saunders L, Bubb KL, Trapnell C, Fields S, Queitsch C, Cuperus JT The Plant cell 30923229 Plant Cell 2019 May https://www.ncbi.nlm.nih.gov/pubmed/30923229
A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility. Cusanovich DA, Hill AJ, Aghamirzaie D, Daza RM, Pliner HA, Berletch JB, Filippova GN, Huang X, Christiansen L, DeWitt WS, Lee C, Regalado SG, Read DF, Steemers FJ, Disteche CM, Trapnell C, Shendure J Cell 30078704 Cell 2018 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/30078704
Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data. Pliner HA, Packer JS, McFaline-Figueroa JL, Cusanovich DA, Daza RM, Aghamirzaie D, Srivatsan S, Qiu X, Jackson D, Minkina A, Adey AC, Steemers FJ, Shendure J, Trapnell C Molecular cell 30078726 Mol Cell 2018 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/30078726
A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gürtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D Cell 30661759 Cell 2019 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/30661759
Sci-fate characterizes the dynamics of gene expression in single cells. Cao J, Zhou W, Steemers F, Trapnell C, Shendure J Nature biotechnology 32284584 Nat Biotechnol 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32284584
Massively multiplex chemical transcriptomics at single-cell resolution. Srivatsan SR, McFaline-Figueroa JL, Ramani V, Saunders L, Cao J, Packer J, Pliner HA, Jackson DL, Daza RM, Christiansen L, Zhang F, Steemers F, Shendure J, Trapnell C Science (New York, N.Y.) 31806696 Science 2020 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/31806696
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy. McFaline-Figueroa JL, Srivatsan S, Hill AJ, Gasperini M, Jackson DL, Saunders L, Domcke S, Regalado SG, Lazarchuck P, Alvarez S, Monnat RJ Jr, Shendure J, Trapnell C bioRxiv : the preprint server for biology 37398090 bioRxiv 2023 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/37398090
High-throughput, microscope-based sorting to dissect cellular heterogeneity. Hasle N, Cooke A, Srivatsan S, Huang H, Stephany JJ, Krieger Z, Jackson D, Tang W, Pendyala S, Monnat RJ Jr, Trapnell C, Hatch EM, Fowler DM Molecular systems biology 32500953 Mol Syst Biol 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32500953
A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition. McFaline-Figueroa JL, Hill AJ, Qiu X, Jackson D, Shendure J, Trapnell C Nature genetics 31477929 Nat Genet 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31477929
Dimensionality reduction by UMAP to visualize physical and genetic interactions. Dorrity MW, Saunders LM, Queitsch C, Fields S, Trapnell C Nature communications 32210240 Nat Commun 2020 Mar 24 https://www.ncbi.nlm.nih.gov/pubmed/32210240
Activated CARD11 accelerates germinal center kinetics, promoting mTORC1 and terminal differentiation. Wray-Dutra MN, Chawla R, Thomas KR, Seymour BJ, Arkatkar T, Sommer KM, Khim S, Trapnell C, James RG, Rawlings DJ The Journal of experimental medicine 30127060 J Exp Med 2018 Sep 3 https://www.ncbi.nlm.nih.gov/pubmed/30127060
Joint profiling of chromatin accessibility and gene expression in thousands of single cells. Cao J, Cusanovich DA, Ramani V, Aghamirzaie D, Pliner HA, Hill AJ, Daza RM, McFaline-Figueroa JL, Packer JS, Christiansen L, Steemers FJ, Adey AC, Trapnell C, Shendure J Science (New York, N.Y.) 30166440 Science 2018 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/30166440
IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer. Furlan SN, Singh K, Lopez C, Tkachev V, Hunt DJ, Hibbard J, Betz KM, Blazar BR, Trapnell C, Kean LS Blood advances 32311015 Blood Adv 2020 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/32311015
Supervised classification enables rapid annotation of cell atlases. Pliner HA, Shendure J, Trapnell C Nature methods 31501545 Nat Methods 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31501545
Single-cell mRNA quantification and differential analysis with Census. Qiu X, Hill A, Packer J, Lin D, Ma YA, Trapnell C Nature methods 28114287 Nat Methods 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28114287
The single-cell transcriptional landscape of mammalian organogenesis. Cao J, Spielmann M, Qiu X, Huang X, Ibrahim DM, Hill AJ, Zhang F, Mundlos S, Christiansen L, Steemers FJ, Trapnell C, Shendure J Nature 30787437 Nature 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30787437
A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens. Gasperini M, Hill AJ, McFaline-Figueroa JL, Martin B, Kim S, Zhang MD, Jackson D, Leith A, Schreiber J, Noble WS, Trapnell C, Ahituv N, Shendure J Cell 30612741 Cell 2019 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/30612741
On the design of CRISPR-based single-cell molecular screens. Hill AJ, McFaline-Figueroa JL, Starita LM, Gasperini MJ, Matreyek KA, Packer J, Jackson D, Shendure J, Trapnell C Nature methods 29457792 Nat Methods 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29457792
iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice. Mucci A, Lopez-Rodriguez E, Hetzel M, Liu S, Suzuki T, Happle C, Ackermann M, Kempf H, Hillje R, Kunkiel J, Janosz E, Brennig S, Glage S, Bankstahl JP, Dettmer S, Rodt T, Gohring G, Trapnell B, Hansen G, Trapnell C, Knudsen L, Lachmann N, Moritz T Stem cell reports 30100408 Stem Cell Reports 2018 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/30100408
Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. Cacchiarelli D, Qiu X, Srivatsan S, Manfredi A, Ziller M, Overbey E, Grimaldi A, Grimsby J, Pokharel P, Livak KJ, Li S, Meissner A, Mikkelsen TS, Rinn JL, Trapnell C Cell systems 30195438 Cell Syst 2018 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/30195438
Single-cell transcriptomics reveals receptor transformations during olfactory neurogenesis. Hanchate NK, Kondoh K, Lu Z, Kuang D, Ye X, Qiu X, Pachter L, Trapnell C, Buck LB Science (New York, N.Y.) 26541607 Science 2015 Dec 4 https://www.ncbi.nlm.nih.gov/pubmed/26541607
Single-cell transcriptome sequencing: recent advances and remaining challenges. Liu S, Trapnell C F1000Research 26949524 F1000Res 2016 https://www.ncbi.nlm.nih.gov/pubmed/26949524
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy. McFaline-Figueroa JL, Srivatsan S, Hill AJ, Gasperini M, Jackson DL, Saunders L, Domcke S, Regalado SG, Lazarchuck P, Alvarez S, Monnat RJ Jr, Shendure J, Trapnell C Cell genomics 38278156 Cell Genom 2024 Feb 14 https://www.ncbi.nlm.nih.gov/pubmed/38278156
MaveDB 2024: a curated community database with over seven million variant effects from multiplexed functional assays. Rubin AF, Stone J, Bianchi AH, Capodanno BJ, Da EY, Dias M, Esposito D, Frazer J, Fu Y, Grindstaff SB, Harrington MR, Li I, McEwen AE, Min JK, Moore N, Moscatelli OG, Ong J, Polunina PV, Rollins JE, Rollins NJ, Snyder AE, Tam A, Wakefield MJ, Ye SS, Starita LM, Bryant VL, Marks DS, Fowler DM Genome biology 39838450 Genome Biol 2025 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/39838450
Cortical neuroprosthetics from a clinical perspective. Tsu AP, Burish MJ, GodLove J, Ganguly K Neurobiology of disease 26253606 Neurobiol Dis 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26253606
Flexible regulation of representations on a drifting manifold enables long-term stable complex neuroprosthetic control. Natraj N, Seko S, Abiri R, Yan H, Graham Y, Tu-Chan A, Chang EF, Ganguly K bioRxiv : the preprint server for biology 37645922 bioRxiv 2023 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/37645922
Compartmentalized dynamics within a common multi-area mesoscale manifold represent a repertoire of human hand movements. Natraj N, Silversmith DB, Chang EF, Ganguly K Neuron 34678147 Neuron 2022 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/34678147
Plug-and-play control of a brain-computer interface through neural map stabilization. Silversmith DB, Abiri R, Hardy NF, Natraj N, Tu-Chan A, Chang EF, Ganguly K Nature biotechnology 32895549 Nat Biotechnol 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/32895549
Sampling representational plasticity of simple imagined movements across days enables long-term neuroprosthetic control. Natraj N, Seko S, Abiri R, Miao R, Yan H, Graham Y, Tu-Chan A, Chang EF, Ganguly K Cell 40054446 Cell 2025 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/40054446
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Synthetic glycoscapes: addressing the structural and functional complexity of the glycocalyx. Purcell SC, Godula K Interface focus 30842878 Interface Focus 2019 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/30842878
Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism. Trieger GW, Pessentheiner AR, Purcell SC, Green CR, DeForest N, Willert K, Majithia AR, Metallo CM, Godula K, Gordts PLSM The Journal of biological chemistry 36931394 J Biol Chem 2023 May https://www.ncbi.nlm.nih.gov/pubmed/36931394
Embryonic Stem Cell Engineering with a Glycomimetic FGF2/BMP4 Co-Receptor Drives Mesodermal Differentiation in a Three-Dimensional Culture. Naticchia MR, Laubach LK, Tota EM, Lucas TM, Huang ML, Godula K ACS chemical biology 30157624 ACS Chem Biol 2018 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/30157624
Influencing Early Stages of Neuromuscular Junction Formation through Glycocalyx Engineering. Huang ML, Tota EM, Lucas TM, Godula K ACS chemical neuroscience 30095249 ACS Chem Neurosci 2018 Dec 19 https://www.ncbi.nlm.nih.gov/pubmed/30095249
Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Weiss RJ, Spahn PN, Chiang AWT, Liu Q, Li J, Hamill KM, Rother S, Clausen TM, Hoeksema MA, Timm BM, Godula K, Glass CK, Tor Y, Gordts PLSM, Lewis NE, Esko JD Nature chemical biology 33846619 Nat Chem Biol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33846619
Efficient Synthesis of Heparinoid Bioconjugates for Tailoring FGF2 Activity at the Stem Cell-Matrix Interface. Trieger GW, Verespy S 3rd, Gordts PLSM, Godula K Bioconjugate chemistry 30668905 Bioconjug Chem 2019 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/30668905
Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries. Honigfort DJ, Zhang MH, Verespy S, Godula K Faraday discussions 31313786 Faraday Discuss 2019 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/31313786
Synthetic Mucus Nanobarriers for Identification of Glycan-Dependent Primary Influenza A Infection Inhibitors. Cohen M, Senaati HP, Fisher CJ, Huang ML, Gagneux P, Godula K ACS central science 27800553 ACS Cent Sci 2016 Oct 26 https://www.ncbi.nlm.nih.gov/pubmed/27800553
Mucin-mimetic glycan arrays integrating machine learning for analyzing receptor pattern recognition by influenza A viruses. Lucas TM, Gupta C, Altman MO, Sanchez E, Naticchia MR, Gagneux P, Singharoy A, Godula K Chem 34993358 Chem 2021 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/34993358
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD, Narayanan A, Majowicz SA, Kwong EM, McVicar RN, Thacker BE, Glass CA, Yang Z, Torres JL, Golden GJ, Bartels PL, Porell RN, Garretson AF, Laubach L, Feldman J, Yin X, Pu Y, Hauser BM, Caradonna TM, Kellman BP, Martino C, Gordts PLSM, Chanda SK, Schmidt AG, Godula K, Leibel SL, Jose J, Corbett KD, Ward AB, Carlin AF, Esko JD Cell 32970989 Cell 2020 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/32970989
Spatially controlled glycocalyx engineering for growth factor patterning in embryoid bodies. Naticchia MR, Laubach LK, Honigfort DJ, Purcell SC, Godula K Biomaterials science 33409513 Biomater Sci 2021 Mar 10 https://www.ncbi.nlm.nih.gov/pubmed/33409513
Cell surface photoengineering enables modeling of glycocalyx shedding dynamics. Purcell SC, Zhang MH, Honigfort DJ, Ng HJC, Michalak AL, Godula K Chemical science 35756522 Chem Sci 2022 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/35756522
Biologically Derived Neoproteoglycans for Profiling Protein-Glycosaminoglycan Interactions. Porell RN, Follmar JL, Purcell SC, Timm B, Laubach LK, Kozirovskiy D, Thacker BE, Glass CA, Gordts PLSM, Godula K ACS chemical biology 35574759 ACS Chem Biol 2022 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/35574759
Glycocalyx Remodeling with Glycopolymer-Based Proteoglycan Mimetics. Huang ML, Smith RA, Trieger GW, Godula K Methods in molecular biology (Clifton, N.J.) 26537476 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/26537476
Heparin-fibronectin interactions in the development of extracellular matrix insolubility. Raitman I, Huang ML, Williams SA, Friedman B, Godula K, Schwarzbauer JE Matrix biology : journal of the International Society for Matrix Biology 29223498 Matrix Biol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29223498
Glycomaterials for probing host-pathogen interactions and the immune response. Huang ML, Fisher CJ, Godula K Experimental biology and medicine (Maywood, N.J.) 27190259 Exp Biol Med (Maywood) 2016 May https://www.ncbi.nlm.nih.gov/pubmed/27190259
Glycocalyx scaffolding with synthetic nanoscale glycomaterials. Huang ML, Purcell SC, Verespy S III, Wang Y, Godula K Biomaterials science 28616946 Biomater Sci 2017 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/28616946
Stem Cell Microarrays for Assessing Growth Factor Signaling in Engineered Glycan Microenvironments. Michalak AL, Trieger GW, Trieger KA, Godula K Advanced healthcare materials 34541824 Adv Healthc Mater 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/34541824
Small Molecule Antagonist of Cell Surface Glycosaminoglycans Restricts Mouse Embryonic Stem Cells in a Pluripotent State. Huang ML, Michalak AL, Fisher CJ, Christy M, Smith RAA, Godula K Stem cells (Dayton, Ohio) 28984039 Stem Cells 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/28984039
Following sugar patterns in search of galectin function. Godula K Proceedings of the National Academy of Sciences of the United States of America 29496962 Proc Natl Acad Sci U S A 2018 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/29496962
Silencing glycosaminoglycan functions in mouse embryonic stem cells with small molecule antagonists. Chatterjee S, Stephenson TN, Michalak AL, Godula K, Huang ML Methods in enzymology 31606078 Methods Enzymol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31606078
Glycocalyx crowding with mucin mimetics strengthens binding of soluble and virus-associated lectins to host cell glycan receptors. Honigfort DJ, Altman MO, Gagneux P, Godula K Proceedings of the National Academy of Sciences of the United States of America 34583992 Proc Natl Acad Sci U S A 2021 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/34583992
Advances in Decoding Axolotl Limb Regeneration. Haas BJ, Whited JL Trends in genetics : TIG 28648452 Trends Genet 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28648452
Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution. Leigh ND, Dunlap GS, Johnson K, Mariano R, Oshiro R, Wong AY, Bryant DM, Miller BM, Ratner A, Chen A, Ye WW, Haas BJ, Whited JL Nature communications 30514844 Nat Commun 2018 Dec 4 https://www.ncbi.nlm.nih.gov/pubmed/30514844
von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration. Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL Evolution & development 32163674 Evol Dev 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32163674
Parallels between wound healing, epimorphic regeneration and solid tumors. Wong AY, Whited JL Development (Cambridge, England) 31898582 Development 2020 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/31898582
Bioelectrical controls of morphogenesis: from ancient mechanisms of cell coordination to biomedical opportunities. Whited JL, Levin M Current opinion in genetics & development 31442749 Curr Opin Genet Dev 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31442749
Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration. Sousounis K, Bryant DM, Martinez Fernandez J, Eddy SS, Tsai SL, Gundberg GC, Han J, Courtemanche K, Levin M, Whited JL eLife 32142407 Elife 2020 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/32142407
A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors. Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM Jr, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL Cell reports 28099853 Cell Rep 2017 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/28099853
Common themes in tetrapod appendage regeneration: a cellular perspective. Miller BM, Johnson K, Whited JL EvoDevo 31236203 Evodevo 2019 https://www.ncbi.nlm.nih.gov/pubmed/31236203
Repeated removal of developing limb buds permanently reduces appendage size in the highly-regenerative axolotl. Bryant DM, Sousounis K, Farkas JE, Bryant S, Thao N, Guzikowski AR, Monaghan JR, Levin M, Whited JL Developmental biology 28235582 Dev Biol 2017 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/28235582
Identification of regenerative roadblocks via repeat deployment of limb regeneration in axolotls. Bryant DM, Sousounis K, Payzin-Dogru D, Bryant S, Sandoval AGW, Martinez Fernandez J, Mariano R, Oshiro R, Wong AY, Leigh ND, Johnson K, Whited JL NPJ Regenerative medicine 29302364 NPJ Regen Med 2017 https://www.ncbi.nlm.nih.gov/pubmed/29302364
Complement Receptor C5aR1 Plays an Evolutionarily Conserved Role in Successful Cardiac Regeneration. Natarajan N, Abbas Y, Bryant DM, Gonzalez-Rosa JM, Sharpe M, Uygur A, Cocco-Delgado LH, Ho NN, Gerard NP, Gerard CJ, MacRae CA, Burns CE, Burns CG, Whited JL, Lee RT Circulation 29348261 Circulation 2018 May 15 https://www.ncbi.nlm.nih.gov/pubmed/29348261
Systemic cell cycle activation is induced following complex tissue injury in axolotl. Johnson K, Bateman J, DiTommaso T, Wong AY, Whited JL Developmental biology 29111100 Dev Biol 2018 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/29111100
Discussing limb development and regeneration in Barcelona: The future is at hand. Rosello-Diez A, Whited JL Developmental dynamics : an official publication of the American Association of Anatomists 31587395 Dev Dyn 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31587395
A Practical Guide for CRISPR-Cas9-Induced Mutations in Axolotls. Sousounis K, Courtemanche K, Whited JL Methods in molecular biology (Clifton, N.J.) 36272086 Methods Mol Biol 2023 https://www.ncbi.nlm.nih.gov/pubmed/36272086
Automated home cage training of mice in a hold-still center-out reach task. Bollu T, Whitehead SC, Prasad N, Walker J, Shyamkumar N, Subramaniam R, Kardon B, Cohen I, Goldberg JH Journal of neurophysiology 30540551 J Neurophysiol 2019 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/30540551
Motor cortical inactivation impairs corrective submovements in mice performing a hold-still center-out reach task. Bollu T, Whitehead SC, Prasad N, Walker J, Shyamkumar N, Subramaniam R, Kardon B, Cohen I, Goldberg JH Journal of neurophysiology 39081209 J Neurophysiol 2024 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/39081209
Cortex-dependent corrections as the tongue reaches for and misses targets. Bollu T, Ito BS, Whitehead SC, Kardon B, Redd J, Liu MH, Goldberg JH Nature 34012117 Nature 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34012117
Special issue on "recent advances in meiosis from DNA replication to chromosome segregation". Cole F, Borde V Chromosoma 31616989 Chromosoma 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31616989
2018 PLOS Genetics Research Prize: Bundling, stabilizing, organizing-The orchestration of acentriolar spindle assembly by microtubule motor proteins. Barsh GS, Bhalla N, Cole F, Copenhaver GP, Lacefield S, Libuda DE PLoS genetics 30212501 PLoS Genet 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30212501
Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes. Zelazowski MJ, Sandoval M, Paniker L, Hamilton HM, Han J, Gribbell MA, Kang R, Cole F Cell 28942922 Cell 2017 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/28942922
X marks the spot: PRDM9 rescues hybrid sterility by finding hidden treasure in the genome. Zelazowski MJ, Cole F Nature structural & molecular biology 27045445 Nat Struct Mol Biol 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/27045445
Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance. Takata KI, Reh S, Yousefzadeh MJ, Zelazowski MJ, Bhetawal S, Trono D, Lowery MG, Sandoval M, Takata Y, Lu Y, Lin K, Shen J, Kusewitt DF, McBride KM, Cole F, Wood RD PLoS genetics 28570559 PLoS Genet 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28570559
53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1. Li M, Cole F, Patel DS, Misenko SM, Her J, Malhowski A, Alhamza A, Zheng H, Baer R, Ludwig T, Jasin M, Nussenzweig A, Serrano L, Bunting SF EMBO reports 27670884 EMBO Rep 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27670884
RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1. Vélez-Cruz R, Manickavinayaham S, Biswas AK, Clary RW, Premkumar T, Cole F, Johnson DG Genes & development 27940962 Genes Dev 2016 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/27940962
SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. Hansen RK, Mund A, Poulsen SL, Sandoval M, Klement K, Tsouroula K, Tollenaere MA, Räschle M, Soria R, Offermanns S, Worzfeld T, Grosse R, Brandt DT, Rozell B, Mann M, Cole F, Soutoglou E, Goodarzi AA, Daniel JA, Mailand N, Bekker-Jensen S Nature cell biology 27820601 Nat Cell Biol 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27820601
Dynamic reorganization of the genome shapes the recombination landscape in meiotic prophase. Patel L, Kang R, Rosenberg SC, Qiu Y, Raviram R, Chee S, Hu R, Ren B, Cole F, Corbett KD Nature structural & molecular biology 30778236 Nat Struct Mol Biol 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30778236
Missing the Mark: PRDM9-Dependent Methylation Is Required for Meiotic DSB Targeting. Kang R, Zelazowski MJ, Cole F Molecular cell 29499130 Mol Cell 2018 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/29499130
Genetic dissection of crossover mutants defines discrete intermediates in mouse meiosis. Premkumar T, Paniker L, Kang R, Biot M, Humphrey E, Destain H, Ferranti I, Okulate I, Nguyen H, Kilaru V, Frasca M, Chakraborty P, Cole F Molecular cell 37595556 Mol Cell 2023 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/37595556
Transportability of Trial Results Using Inverse Odds of Sampling Weights. Westreich D, Edwards JK, Lesko CR, Stuart E, Cole SR American journal of epidemiology 28535275 Am J Epidemiol 2017 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/28535275
Smoking, HIV, and risk of pregnancy loss. Westreich D, Cates J, Cohen M, Weber KM, Seidman D, Cropsey K, Wright R, Milam J, Young MA, Mehta CC, Gustafson DR, Golub ET, Fischl MA, Adimora AA AIDS (London, England) 27902507 AIDS 2017 Feb 20 https://www.ncbi.nlm.nih.gov/pubmed/27902507
Generalizing Study Results: A Potential Outcomes Perspective. Lesko CR, Buchanan AL, Westreich D, Edwards JK, Hudgens MG, Cole SR Epidemiology (Cambridge, Mass.) 28346267 Epidemiology 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28346267
Commentary: Epidemiology in the era of big data. Mooney SJ, Westreich DJ, El-Sayed AM Epidemiology (Cambridge, Mass.) 25756221 Epidemiology 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25756221
Risk. Cole SR, Hudgens MG, Brookhart MA, Westreich D American journal of epidemiology 25660080 Am J Epidemiol 2015 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/25660080
Using Bounds to Compare the Strength of Exchangeability Assumptions for Internal and External Validity. Breskin A, Westreich D, Cole SR, Edwards JK American journal of epidemiology 30834430 Am J Epidemiol 2019 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/30834430
UK Biobank, big data, and the consequences of non-representativeness. Keyes KM, Westreich D Lancet (London, England) 30938313 Lancet 2019 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/30938313
Generalizing Randomized Clinical Trial Results: Implementation and Challenges Related to Missing Data in the Target Population. Hong JL, Jonsson Funk M, LoCasale R, Dempster SE, Cole SR, Webster-Clark M, Edwards JK, Stürmer T American journal of epidemiology 29020193 Am J Epidemiol 2018 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/29020193
The Authors Respond. Lesko CR, Buchanan AL, Westreich D, Edwards JK, Hudgens MG, Cole SR Epidemiology (Cambridge, Mass.) 29023242 Epidemiology 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29023242
From Patients to Policy: Population Intervention Effects in Epidemiology. Westreich D Epidemiology (Cambridge, Mass.) 28282339 Epidemiology 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28282339
When Is a Complete-Case Approach to Missing Data Valid? The Importance of Effect-Measure Modification. Ross RK, Breskin A, Westreich D American journal of epidemiology 32601706 Am J Epidemiol 2020 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/32601706
Two-stage g-computation: Evaluating Treatment and Intervention Impacts in Observational Cohorts When Exposure Information Is Partly Missing. Breger TL, Edwards JK, Cole SR, Westreich D, Pence BW, Adimora AA Epidemiology (Cambridge, Mass.) 32657953 Epidemiology 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32657953
Causal Impact: Epidemiological Approaches for a Public Health of Consequence. Westreich D, Edwards JK, Rogawski ET, Hudgens MG, Stuart EA, Cole SR American journal of public health 27153017 Am J Public Health 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27153017
Brief Report: Estimating Differences and Ratios in Median Times to Event. Rogawski ET, Westreich DJ, Kang G, Ward HD, Cole SR Epidemiology (Cambridge, Mass.) 27465526 Epidemiology 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27465526
Invited commentary: every good randomization deserves observation. Westreich D, Edwards JK American journal of epidemiology 26487342 Am J Epidemiol 2015 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/26487342
G-computation for policy-relevant effects of interventions on time-to-event outcomes. Breskin A, Edmonds A, Cole SR, Westreich D, Cocohoba J, Cohen MH, Kassaye SG, Metsch LR, Sharma A, Williams MS, Adimora AA International journal of epidemiology 33141177 Int J Epidemiol 2021 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/33141177
A review of time scale fundamentals in the g-formula and insidious selection bias. Keil AP, Edwards JK Current epidemiology reports 30555772 Curr Epidemiol Rep 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30555772
The Effects of Hepatitis C Treatment Eligibility Criteria on All-cause Mortality Among People With Human Immunodeficiency Virus. Breskin A, Westreich D, Hurt CB, Cole SR, Hudgens MG, Seaberg EC, Thio CL, Tien PC, Adimora AA Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 30615096 Clin Infect Dis 2019 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/30615096
Effect of Postnatal HIV Treatment on Clinical Mastitis and Breast Inflammation in HIV-Infected Breast-feeding Women. Zadrozny S, Westreich D, Hudgens MG, Chasela C, Jamieson DJ, Martinson F, Zimba C, Tegha G, Hoffman I, Miller WC, Pence BW, King CC, Kourtis AP, Msungama W, van der Horst C, BAN Study Team Paediatric and perinatal epidemiology 28205255 Paediatr Perinat Epidemiol 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28205255
Primary non-adherence and the new-user design. Li X, Cole SR, Westreich D, Brookhart MA Pharmacoepidemiology and drug safety 29460385 Pharmacoepidemiol Drug Saf 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29460385
Quantifying Cancer Risk from Radiation. Keil AP, Richardson DB Risk analysis : an official publication of the Society for Risk Analysis 29211917 Risk Anal 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29211917
Target Validity and the Hierarchy of Study Designs. Westreich D, Edwards JK, Lesko CR, Cole SR, Stuart EA American journal of epidemiology 30299451 Am J Epidemiol 2019 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/30299451
Generalizing the per-protocol treatment effect: The case of ACTG A5095. Lu H, Cole SR, Hall HI, Schisterman EF, Breger TL, K Edwards J, Westreich D Clinical trials (London, England) 30326736 Clin Trials 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30326736
Incident obstructive lung disease and mortality among people with HIV and a history of injecting drugs. Kalmin MM, Westreich D, Drummond BM, Sun J, Mehta SH, Kirk GD AIDS (London, England) 33831913 AIDS 2021 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/33831913
A longitudinal, HIV care continuum: 10-year restricted mean time in each care continuum stage after enrollment in care, by history of IDU. Lesko CR, Edwards JK, Moore RD, Lau B AIDS (London, England) 27314178 AIDS 2016 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/27314178
Exploring the Subtleties of Inverse Probability Weighting and Marginal Structural Models. Breskin A, Cole SR, Westreich D Epidemiology (Cambridge, Mass.) 29384789 Epidemiology 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29384789
Invited Commentary: Beware the Test-Negative Design. Westreich D, Hudgens MG American journal of epidemiology 27587722 Am J Epidemiol 2016 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/27587722
Generalizability of randomized trial results to target populations: Design and analysis possibilities. Stuart EA, Ackerman B, Westreich D Research on social work practice 30034203 Res Soc Work Pract 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/30034203
Body mass index, calcium supplementation and risk of colorectal adenomas. Barry EL, Lund JL, Westreich D, Mott LA, Ahnen DJ, Beck GJ, Bostick RM, Bresalier RS, Burke CA, Church TR, Rees JR, Robertson DJ, Baron JA International journal of cancer 30117164 Int J Cancer 2019 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/30117164
Comparison of Methods to Generalize Randomized Clinical Trial Results Without Individual-Level Data for the Target Population. Hong JL, Webster-Clark M, Jonsson Funk M, Stürmer T, Dempster SE, Cole SR, Herr I, LoCasale R American journal of epidemiology 30312378 Am J Epidemiol 2019 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/30312378
The Effects of Hepatitis C Infection and Treatment on All-cause Mortality Among People Living With Human Immunodeficiency Virus. Breskin A, Westreich D, Cole SR, Hudgens MG, Hurt CB, Seaberg EC, Thio CL, Tien PC, Adimora AA Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 30321289 Clin Infect Dis 2019 Mar 19 https://www.ncbi.nlm.nih.gov/pubmed/30321289
Marginal Structural Models for Risk or Prevalence Ratios for a Point Exposure Using a Disease Risk Score. Richardson DB, Keil AP, Kinlaw AC, Cole SR American journal of epidemiology 30726868 Am J Epidemiol 2019 May 1 https://www.ncbi.nlm.nih.gov/pubmed/30726868
The Impact of Implementation Fidelity on Mortality Under a CD4-Stratified Timing Strategy for Antiretroviral Therapy in Patients With Tuberculosis. Patel MR, Westreich D, Yotebieng M, Nana M, Eron JJ, Behets F, Van Rie A American journal of epidemiology 25787266 Am J Epidemiol 2015 May 1 https://www.ncbi.nlm.nih.gov/pubmed/25787266
Thirteen Questions About Using Machine Learning in Causal Research (You Won't Believe the Answer to Number 10!). Mooney SJ, Keil AP, Westreich DJ American journal of epidemiology 33751024 Am J Epidemiol 2021 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/33751024
The effect of early life antibiotic exposures on diarrheal rates among young children in Vellore, India. Rogawski ET, Westreich D, Becker-Dreps S, Adair LS, Sandler RS, Sarkar R, Kattula D, Ward HD, Meshnick SR, Kang G The Pediatric infectious disease journal 25742244 Pediatr Infect Dis J 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25742244
Age at Entry Into Care, Timing of Antiretroviral Therapy Initiation, and 10-Year Mortality Among HIV-Seropositive Adults in the United States. Edwards JK, Cole SR, Westreich D, Mugavero MJ, Eron JJ, Moore RD, Mathews WC, Hunt P, Williams C, Centers for AIDS Research Network of Integrated Clinical Systems investigators Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 26082505 Clin Infect Dis 2015 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/26082505
You are smarter than you think: (super) machine learning in context. Keil AP, Edwards JK European journal of epidemiology 29744711 Eur J Epidemiol 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29744711
RESOLVING AN APPARENT PARADOX IN DOUBLY ROBUST ESTIMATORS. Keil AP, Mooney SJ, Jonsson Funk M, Cole SR, Edwards JK, Westreich D American journal of epidemiology 29394330 Am J Epidemiol 2018 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/29394330
Toward a Clearer Definition of Selection Bias When Estimating Causal Effects. Lu H, Cole SR, Howe CJ, Westreich D Epidemiology (Cambridge, Mass.) 35700187 Epidemiology 2022 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/35700187
Improving Depression Among HIV-Infected Adults: Transporting the Effect of a Depression Treatment Intervention to Routine Care. Bengtson AM, Pence BW, Gaynes BN, Quinlivan EB, Heine AD, OʼDonnell JK, Crane HM, Mathews WC, Moore RD, Westreich D, OʼCleirigh C, Christopoulos K, Mimiaga MJ, Mugavero MJ Journal of acquired immune deficiency syndromes (1999) 27668804 J Acquir Immune Defic Syndr 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27668804
An Illustration of Inverse Probability Weighting to Estimate Policy-Relevant Causal Effects. Edwards JK, Cole SR, Lesko CR, Mathews WC, Moore RD, Mugavero MJ, Westreich D American journal of epidemiology 27469514 Am J Epidemiol 2016 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/27469514
Baseline Characteristics Explain Differences in Effectiveness of Randomization to Daily Oral TDF/FTC PrEP Between Transgender Women and Cisgender Men Who Have Sex With Men in the iPrEx Trial. Mehrotra ML, Westreich D, McMahan VM, Glymour MM, Geng E, Grant RM, Glidden DV Journal of acquired immune deficiency syndromes (1999) 31192894 J Acquir Immune Defic Syndr 2019 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/31192894
Transporting Subgroup Analyses of Randomized Controlled Trials for Planning Implementation of New Interventions. Mehrotra ML, Westreich D, Glymour MM, Geng E, Glidden DV American journal of epidemiology 33615327 Am J Epidemiol 2021 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/33615327
The Authors Respond. Breskin A, Cole SR, Hudgens MG Epidemiology (Cambridge, Mass.) 30052540 Epidemiology 2018 Nov https://www.ncbi.nlm.nih.gov/pubmed/30052540
Inverse Probability Weights for the Analysis of Polytomous Outcomes. Richardson DB, Kinlaw AC, Keil AP, Naimi AI, Kaufman JS, Cole SR American journal of epidemiology 29390115 Am J Epidemiol 2018 May 1 https://www.ncbi.nlm.nih.gov/pubmed/29390115
An updated systematic review of epidemiological evidence on hormonal contraceptive methods and HIV acquisition in women. Polis CB, Curtis KM, Hannaford PC, Phillips SJ, Chipato T, Kiarie JN, Westreich DJ, Steyn PS AIDS (London, England) 27500670 AIDS 2016 Nov 13 https://www.ncbi.nlm.nih.gov/pubmed/27500670
Invited Commentary: Causal Inference Across Space and Time-Quixotic Quest, Worthy Goal, or Both? Edwards JK, Lesko CR, Keil AP American journal of epidemiology 28679174 Am J Epidemiol 2017 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/28679174
Misclassification in defining and diagnosing microcephaly. Kalmin MM, Gower EW, Stringer EM, Bowman NM, Rogawski McQuade ET, Westreich D Paediatric and perinatal epidemiology 31347726 Paediatr Perinat Epidemiol 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31347726
Estimating the Impact of Changes to Occupational Standards for Silica Exposure on Lung Cancer Mortality. Keil AP, Richardson DB, Westreich D, Steenland K Epidemiology (Cambridge, Mass.) 29870429 Epidemiology 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/29870429
Use of electronic health record data and machine learning to identify candidates for HIV pre-exposure prophylaxis: a modelling study. Marcus JL, Hurley LB, Krakower DS, Alexeeff S, Silverberg MJ, Volk JE The lancet. HIV 31285183 Lancet HIV 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31285183
Early Life Antibiotic Exposure Is Not Associated with Growth in Young Children of Vellore, India. Rogawski ET, Westreich DJ, Adair LS, Becker-Dreps S, Sandler RS, Sarkar R, Kattula D, Ward HD, Meshnick S, Kang G The Journal of pediatrics 26372535 J Pediatr 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26372535
The effect of antiretroviral therapy on all-cause mortality, generalized to persons diagnosed with HIV in the USA, 2009-11. Lesko CR, Cole SR, Hall HI, Westreich D, Miller WC, Eron JJ, Li J, Mugavero MJ, CNICS Investigators International journal of epidemiology 26772869 Int J Epidemiol 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26772869
Reduction in diarrhoeal rates through interventions that prevent unnecessary antibiotic exposure early in life in an observational birth cohort. Rogawski ET, Meshnick SR, Becker-Dreps S, Adair LS, Sandler RS, Sarkar R, Kattula D, Ward HD, Kang G, Westreich DJ Journal of epidemiology and community health 26621194 J Epidemiol Community Health 2016 May https://www.ncbi.nlm.nih.gov/pubmed/26621194
Use of Intrauterine Devices and Risk of Human Immunodeficiency Virus Acquisition Among Insured Women in the United States. Marcus JL, Snowden JM, Murray Horwitz ME, Toh S, Horgan C, Tilney RC, Rajbhandari R, Back S, Westreich DJ Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 31412356 Clin Infect Dis 2020 May 6 https://www.ncbi.nlm.nih.gov/pubmed/31412356
The Intersections of COVID-19, HIV, and Race/Ethnicity: Machine Learning Methods to Identify and Model Risk Factors for Severe COVID-19 in a Large U.S. National Dataset. Kunz M, Rott KW, Hurwitz E, Kunisaki K, Sun J, Wilkins KJ, Islam JY, Patel R, Safo SE, National Covid Cohort Collaborative (N3C) Consortium AIDS and behavior 38326668 AIDS Behav 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/38326668
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens. Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC Nature communications 28474669 Nat Commun 2017 May 5 https://www.ncbi.nlm.nih.gov/pubmed/28474669
Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs. Gu S, Zhang Y, Jin L, Huang Y, Zhang F, Bassik MC, Kampmann M, Kay MA Nucleic acids research 25270879 Nucleic Acids Res 2014 Oct 29 https://www.ncbi.nlm.nih.gov/pubmed/25270879
CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity. Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC Nature chemical biology 31451760 Nat Chem Biol 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31451760
Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway. Dubreuil MM, Morgens DW, Okumoto K, Honsho M, Contrepois K, Lee-McMullen B, Traber GM, Sood RS, Dixon SJ, Snyder MP, Fujiki Y, Bassik MC Cell reports 32023459 Cell Rep 2020 Feb 4 https://www.ncbi.nlm.nih.gov/pubmed/32023459
Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. Jeng EE, Bhadkamkar V, Ibe NU, Gause H, Jiang L, Chan J, Jian R, Jimenez-Morales D, Stevenson E, Krogan NJ, Swaney DL, Snyder MP, Mukherjee S, Bassik MC Cell host & microbe 31540829 Cell Host Microbe 2019 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/31540829
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, Bassik MC, Aigner L, Wyss-Coray T Nature neuroscience 31959936 Nat Neurosci 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31959936
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators. Liu N, Lee CH, Swigut T, Grow E, Gu B, Bassik MC, Wysocka J Nature 29211708 Nature 2018 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/29211708
Next-generation libraries for robust RNA interference-based genome-wide screens. Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS Proceedings of the National Academy of Sciences of the United States of America 26080438 Proc Natl Acad Sci U S A 2015 Jun 30 https://www.ncbi.nlm.nih.gov/pubmed/26080438
SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy. Wang Z, Hausmann S, Lyu R, Li TM, Lofgren SM, Flores NM, Fuentes ME, Caporicci M, Yang Z, Meiners MJ, Cheek MA, Howard SA, Zhang L, Elias JE, Kim MP, Maitra A, Wang H, Bassik MC, Keogh MC, Sage J, Gozani O, Mazur PK Cancer cell 32442403 Cancer Cell 2020 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/32442403
CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, Gitler AD Nature genetics 29507424 Nat Genet 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29507424
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis. Kamber RA, Nishiga Y, Morton B, Banuelos AM, Barkal AA, Vences-Catalán F, Gu M, Fernandez D, Seoane JA, Yao D, Liu K, Lin S, Spees K, Curtis C, Jerby-Arnon L, Weissman IL, Sage J, Bassik MC Nature 34497417 Nature 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34497417
LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP. Lahey LJ, Mardjuki RE, Wen X, Hess GT, Ritchie C, Carozza JA, Böhnert V, Maduke M, Bassik MC, Li L Molecular cell 33171122 Mol Cell 2020 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/33171122
Unraveling the mechanism of cell death induced by chemical fibrils. Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA Nature chemical biology 25262416 Nat Chem Biol 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25262416
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS Cell 25307932 Cell 2014 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/25307932
Translation readthrough mitigation. Arribere JA, Cenik ES, Jain N, Hess GT, Lee CH, Bassik MC, Fire AZ Nature 27281202 Nature 2016 Jun 30 https://www.ncbi.nlm.nih.gov/pubmed/27281202
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC Nature biotechnology 28319085 Nat Biotechnol 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28319085
KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics. Milic B, Chakraborty A, Han K, Bassik MC, Block SM Proceedings of the National Academy of Sciences of the United States of America 29703754 Proc Natl Acad Sci U S A 2018 May 15 https://www.ncbi.nlm.nih.gov/pubmed/29703754
Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. Hess GT, Frésard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC Nature methods 27798611 Nat Methods 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27798611
Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs. Lu A, Wawro P, Morgens DW, Portela F, Bassik MC, Pfeffer SR eLife 30556811 Elife 2018 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/30556811
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. Liu S, Hausmann S, Carlson SM, Fuentes ME, Francis JW, Pillai R, Lofgren SM, Hulea L, Tandoc K, Lu J, Li A, Nguyen ND, Caporicci M, Kim MP, Maitra A, Wang H, Wistuba II, Porco JA Jr, Bassik MC, Elias JE, Song J, Topisirovic I, Van Rechem C, Mazur PK, Gozani O Cell 30612740 Cell 2019 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/30612740
Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes. Morgens DW, Deans RM, Li A, Bassik MC Nature biotechnology 27159373 Nat Biotechnol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27159373
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes. Wainberg M, Kamber RA, Balsubramani A, Meyers RM, Sinnott-Armstrong N, Hornburg D, Jiang L, Chan J, Jian R, Gu M, Shcherbina A, Dubreuil MM, Spees K, Meuleman W, Snyder MP, Bassik MC, Kundaje A Nature genetics 33859415 Nat Genet 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33859415
Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins. Morgens DW, Chan C, Kane AJ, Weir NR, Li A, Dubreuil MM, Tsui CK, Hess GT, Lavertu A, Han K, Polyakov N, Zhou J, Handy EL, Alabi P, Dombroski A, Yao D, Altman RB, Sello JK, Denic V, Bassik MC eLife 31674906 Elife 2019 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/31674906
Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages. Cohen A, Jeng EE, Voorhies M, Symington J, Ali N, Rodriguez RA, Bassik MC, Sil A PLoS pathogens 36174103 PLoS Pathog 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/36174103
An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. Coukos R, Yao D, Sanchez MI, Strand ET, Olive ME, Udeshi ND, Weissman JS, Carr SA, Bassik MC, Ting AY eLife 34414886 Elife 2021 Aug 20 https://www.ncbi.nlm.nih.gov/pubmed/34414886
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification. Deans RM, Morgens DW, Ökesli A, Pillay S, Horlbeck MA, Kampmann M, Gilbert LA, Li A, Mateo R, Smith M, Glenn JS, Carette JE, Khosla C, Bassik MC Nature chemical biology 27018887 Nat Chem Biol 2016 May https://www.ncbi.nlm.nih.gov/pubmed/27018887
E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia. Duque-Afonso J, Lin CH, Han K, Wei MC, Feng J, Kurzer JH, Schneidawind C, Wong SH, Bassik MC, Cleary ML Cancer research 27758892 Cancer Res 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27758892
SLC19A1 Is an Importer of the Immunotransmitter cGAMP. Ritchie C, Cordova AF, Hess GT, Bassik MC, Li L Molecular cell 31126740 Mol Cell 2019 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/31126740
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus. Leonardi W, Zilbermintz L, Cheng LW, Zozaya J, Tran SH, Elliott JH, Polukhina K, Manasherob R, Li A, Chi X, Gharaibeh D, Kenny T, Zamani R, Soloveva V, Haddow AD, Nasar F, Bavari S, Bassik MC, Cohen SN, Levitin A, Martchenko M Scientific reports 27686742 Sci Rep 2016 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/27686742
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes. Hess GT, Tycko J, Yao D, Bassik MC Molecular cell 28985508 Mol Cell 2017 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/28985508
Human pyrimidine nucleotide biosynthesis as a target for antiviral chemotherapy. Okesli A, Khosla C, Bassik MC Current opinion in biotechnology 28458037 Curr Opin Biotechnol 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/28458037
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities. Han K, Pierce SE, Li A, Spees K, Anderson GR, Seoane JA, Lo YH, Dubreuil M, Olivas M, Kamber RA, Wainberg M, Kostyrko K, Kelly MR, Yousefi M, Simpkins SW, Yao D, Lee K, Kuo CJ, Jackson PK, Sweet-Cordero A, Kundaje A, Gentles AJ, Curtis C, Winslow MM, Bassik MC Nature 32238925 Nature 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32238925
A genome-wide analysis of targets of macrolide antibiotics in mammalian cells. Gupta A, Ökesli-Armlovich A, Morgens D, Bassik MC, Khosla C The Journal of biological chemistry 31915244 J Biol Chem 2020 Feb 14 https://www.ncbi.nlm.nih.gov/pubmed/31915244
Phenome-based gene discovery provides information about Parkinson's disease drug targets. Chen Y, Xu R BMC genomics 27586503 BMC Genomics 2016 Aug 31 https://www.ncbi.nlm.nih.gov/pubmed/27586503
Combining automatic table classification and relationship extraction in extracting anticancer drug-side effect pairs from full-text articles. Xu R, Wang Q Journal of biomedical informatics 25445920 J Biomed Inform 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25445920
Psoriasis and Psoriatic Arthritis Cardiovascular Disease Endotypes Identified by Red Blood Cell Distribution Width and Mean Platelet Volume. Conic RR, Damiani G, Schrom KP, Ramser AE, Zheng C, Xu R, McCormick TS, Cooper KD Journal of clinical medicine 31936662 J Clin Med 2020 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/31936662
Association of Epigenetic Clock with Consensus Molecular Subtypes and Overall Survival of Colorectal Cancer. Zheng C, Li L, Xu R Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 31375479 Cancer Epidemiol Biomarkers Prev 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31375479
Disease comorbidity-guided drug repositioning: a case study in schizophrenia. Wang Q, Xu R AMIA ... Annual Symposium proceedings. AMIA Symposium 30815174 AMIA Annu Symp Proc 2018 https://www.ncbi.nlm.nih.gov/pubmed/30815174
Immunotherapy-related adverse events (irAEs): extraction from FDA drug labels and comparative analysis. Wang Q, Xu R JAMIA open 30976759 JAMIA Open 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30976759
Context-sensitive network analysis identifies food metabolites associated with Alzheimer's disease: an exploratory study. Chen Y, Xu R BMC medical genomics 30704467 BMC Med Genomics 2019 Jan 31 https://www.ncbi.nlm.nih.gov/pubmed/30704467
Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment. Nagaraj AB, Wang QQ, Joseph P, Zheng C, Chen Y, Kovalenko O, Singh S, Armstrong A, Resnick K, Zanotti K, Waggoner S, Xu R, DiFeo A Oncogene 28967908 Oncogene 2018 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/28967908
Epigenetic age acceleration and clinical outcomes in gliomas. Zheng C, Berger NA, Li L, Xu R PloS one 32692766 PLoS One 2020 https://www.ncbi.nlm.nih.gov/pubmed/32692766
PhenoPredict: A disease phenome-wide drug repositioning approach towards schizophrenia drug discovery. Xu R, Wang Q Journal of biomedical informatics 26151312 J Biomed Inform 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26151312
A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat. Xu R, Wang Q, Li L BMC genomics 26100814 BMC Genomics 2015 https://www.ncbi.nlm.nih.gov/pubmed/26100814
DenguePredict: An Integrated Drug Repositioning Approach towards Drug Discovery for Dengue. Wang Q, Xu R AMIA ... Annual Symposium proceedings. AMIA Symposium 26958268 AMIA Annu Symp Proc 2015 https://www.ncbi.nlm.nih.gov/pubmed/26958268
tcTKB: an integrated cardiovascular toxicity knowledge base for targeted cancer drugs. Xu R, Wang Q AMIA ... Annual Symposium proceedings. AMIA Symposium 26958275 AMIA Annu Symp Proc 2015 https://www.ncbi.nlm.nih.gov/pubmed/26958275
Large-scale automatic extraction of side effects associated with targeted anticancer drugs from full-text oncological articles. Xu R, Wang Q Journal of biomedical informatics 25817969 J Biomed Inform 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25817969
Disease Comorbidity Network Guides the Detection of Molecular Evidence for the Link Between Colorectal Cancer and Obesity. Chen Y, Li L, Xu R AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science 26306270 AMIA Jt Summits Transl Sci Proc 2015 https://www.ncbi.nlm.nih.gov/pubmed/26306270
GLP-1 Receptor Agonists and Colorectal Cancer Risk in Drug-Naive Patients With Type 2 Diabetes, With and Without Overweight/Obesity. Wang L, Wang W, Kaelber DC, Xu R, Berger NA JAMA oncology 38060218 JAMA Oncol 2024 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/38060218
Integrin β3-Mediated Cell Senescence Associates with Gut Inflammation and Intestinal Degeneration in Models of Alzheimer's Disease. Tun X, Wang EJ, Gao Z, Lundberg K, Xu R, Hu D International journal of molecular sciences 36982771 Int J Mol Sci 2023 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/36982771
A Drug-Side Effect Context-Sensitive Network approach for drug target prediction. Zhou M, Chen Y, Xu R Bioinformatics (Oxford, England) 30428013 Bioinformatics 2019 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/30428013
Context-sensitive network-based disease genetics prediction and its implications in drug discovery. Chen Y, Xu R Bioinformatics (Oxford, England) 28062449 Bioinformatics 2017 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/28062449
Association of Aspirin Use with Reduced Risk of Developing Alzheimer's Disease in Elderly Ischemic Stroke Patients: A Retrospective Cohort Study. Gorenflo MP, Davis PB, Kendall EK, Olaker VR, Kaelber DC, Xu R Journal of Alzheimer's disease : JAD 36502331 J Alzheimers Dis 2023 https://www.ncbi.nlm.nih.gov/pubmed/36502331
CoMNRank: An integrated approach to extract and prioritize human microbial metabolites from MEDLINE records. Wang Q, Xu R Journal of biomedical informatics 32791237 J Biomed Inform 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32791237
Drug repurposing for opioid use disorders: integration of computational prediction, clinical corroboration, and mechanism of action analyses. Zhou M, Wang Q, Zheng C, John Rush A, Volkow ND, Xu R Molecular psychiatry 33432189 Mol Psychiatry 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/33432189
A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease. Shang Y, Sun X, Chen X, Wang Q, Wang EJ, Miller E, Xu R, Pieper AA, Qi X Acta neuropathologica 36104602 Acta Neuropathol 2022 Nov https://www.ncbi.nlm.nih.gov/pubmed/36104602
ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models. Zhao Y, Hu D, Wang R, Sun X, Ropelewski P, Hubler Z, Lundberg K, Wang Q, Adams DJ, Xu R, Qi X Nature communications 35236834 Nat Commun 2022 Mar 2 https://www.ncbi.nlm.nih.gov/pubmed/35236834
Glucagon-Like Peptide 1 Receptor Agonists and 13 Obesity-Associated Cancers in Patients With Type 2 Diabetes. Wang L, Xu R, Kaelber DC, Berger NA JAMA network open 38967919 JAMA Netw Open 2024 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/38967919
Explore Small Molecule-induced Genome-wide Transcriptional Profiles for Novel Inflammatory Bowel Disease Drug. Cai X, Chen Y, Gao Z, Xu R AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science 27570643 AMIA Jt Summits Transl Sci Proc 2016 https://www.ncbi.nlm.nih.gov/pubmed/27570643
Combining Human Disease Genetics and Mouse Model Phenotypes towards Drug Repositioning for Parkinson's disease. Chen Y, Cai X, Xu R AMIA ... Annual Symposium proceedings. AMIA Symposium 26958284 AMIA Annu Symp Proc 2015 https://www.ncbi.nlm.nih.gov/pubmed/26958284
Combining mechanism-based prediction with patient-based profiling for psoriasis metabolomics biomarker discovery. Wang Q, McCormick TS, Ward NL, Cooper KD, Conic R, Xu R AMIA ... Annual Symposium proceedings. AMIA Symposium 29854244 AMIA Annu Symp Proc 2017 https://www.ncbi.nlm.nih.gov/pubmed/29854244
MetabolitePredict: A de novo human metabolomics prediction system and its applications in rheumatoid arthritis. Wang Q, Xu R Journal of biomedical informatics 28600026 J Biomed Inform 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28600026
Predict drug permeability to blood-brain-barrier from clinical phenotypes: drug side effects and drug indications. Gao Z, Chen Y, Cai X, Xu R Bioinformatics (Oxford, England) 27993785 Bioinformatics 2017 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/27993785
Drug repurposing for glioblastoma based on molecular subtypes. Chen Y, Xu R Journal of biomedical informatics 27697594 J Biomed Inform 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27697594
Evaluating class III antiarrhythmic agents as novel MYC targeting drugs in ovarian cancer. Belur Nagaraj A, Joseph P, Kovalenko O, Wang Q, Xu R, DiFeo A Gynecologic oncology 30301560 Gynecol Oncol 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30301560
Automatic construction of a large-scale and accurate drug-side-effect association knowledge base from biomedical literature. Xu R, Wang Q Journal of biomedical informatics 24928448 J Biomed Inform 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/24928448
Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R Alzheimer's & dementia : the journal of the Alzheimer's Association 34569707 Alzheimers Dement 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/34569707
Analysis of disease organ as a novel phenotype towards disease genetics understanding. Luo L, Zheng C, Wang J, Tan M, Li Y, Xu R Journal of biomedical informatics 31207382 J Biomed Inform 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31207382
Tumor Necrosis Factor (TNF) blocking agents are associated with lower risk for Alzheimer's disease in patients with rheumatoid arthritis and psoriasis. Zhou M, Xu R, Kaelber DC, Gurney ME PloS one 32203525 PLoS One 2020 https://www.ncbi.nlm.nih.gov/pubmed/32203525
Correction: COVID-19 risk and outcomes in patients with substance use disorders: analyses from electronic health records in the United States. Wang QQ, Kaelber DC, Xu R, Volkow ND Molecular psychiatry 32999436 Mol Psychiatry 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/32999436
COVID-19 risk, disparities and outcomes in patients with chronic liver disease in the United States. Wang Q, Davis PB, Xu R EClinicalMedicine 33521611 EClinicalMedicine 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33521611
COVID-19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US. Wang Q, Davis PB, Gurney ME, Xu R Alzheimer's & dementia : the journal of the Alzheimer's Association 33559975 Alzheimers Dement 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/33559975
When hematologic malignancies meet COVID-19 in the United States: Infections, death and disparities. Wang Q, Berger NA, Xu R Blood reviews 33187811 Blood Rev 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33187811
Aspirin Use and Risk of Alzheimer's Disease: A 2-Sample Mendelian Randomization Study. Ding P, Gorenflo MP, Zhu X, Xu R Journal of Alzheimer's disease : JAD 36846997 J Alzheimers Dis 2023 https://www.ncbi.nlm.nih.gov/pubmed/36846997
Comorbidity-driven multi-modal subtype analysis in mild cognitive impairment of Alzheimer's disease. Katabathula S, Davis PB, Xu R Alzheimer's & dementia : the journal of the Alzheimer's Association 36166485 Alzheimers Dement 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36166485
Glucagon-like peptide-1 receptor agonists and pancreatic cancer risk: target trial emulation using real-world data. Wang L, Wang Q, Li L, Kaelber DC, Xu R Journal of the National Cancer Institute 39418202 J Natl Cancer Inst 2025 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/39418202
Comparative analysis of a novel disease phenotype network based on clinical manifestations. Chen Y, Zhang X, Zhang GQ, Xu R Journal of biomedical informatics 25277758 J Biomed Inform 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25277758
Phenome-driven disease genetics prediction toward drug discovery. Chen Y, Li L, Zhang GQ, Xu R Bioinformatics (Oxford, England) 26072493 Bioinformatics 2015 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/26072493
Network-based gene prediction for Plasmodium falciparum malaria towards genetics-based drug discovery. Chen Y, Xu R BMC genomics 26099491 BMC Genomics 2015 https://www.ncbi.nlm.nih.gov/pubmed/26099491
Automatic extraction, prioritization and analysis of gut microbial metabolites from biomedical literature. Wang Q, Xu R Scientific reports 32561832 Sci Rep 2020 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/32561832
Combining phenome-driven drug-target interaction prediction with patients' electronic health records-based clinical corroboration toward drug discovery. Zhou M, Zheng C, Xu R Bioinformatics (Oxford, England) 32657406 Bioinformatics 2020 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/32657406
A systems biology approach to predict and characterize human gut microbial metabolites in colorectal cancer. Wang Q, Li L, Xu R Scientific reports 29670137 Sci Rep 2018 Apr 18 https://www.ncbi.nlm.nih.gov/pubmed/29670137
Interrogating Patient-level Genomics and Mouse Phenomics towards Understanding Cytokines in Colorectal Cancer Metastasis. Cai X, Chen Y, Zheng C, Xu R AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science 28815134 AMIA Jt Summits Transl Sci Proc 2017 https://www.ncbi.nlm.nih.gov/pubmed/28815134
Sex-Specific Heterogeneity of Mild Cognitive Impairment Identified Based on Multi-Modal Data Analysis. Katabathula S, Davis PB, Xu R, Alzheimer’s Disease Neuroimaging Initiative Journal of Alzheimer's disease : JAD 36404544 J Alzheimers Dis 2023 https://www.ncbi.nlm.nih.gov/pubmed/36404544
A knowledge graph-based disease-gene prediction system using multi-relational graph convolution networks. Gao Z, Pan Y, Ding P, Xu R AMIA ... Annual Symposium proceedings. AMIA Symposium 37128437 AMIA Annu Symp Proc 2022 https://www.ncbi.nlm.nih.gov/pubmed/37128437
Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization. Wang Q, Davis PB, Qi X, Chen SG, Gurney ME, Perry G, Doraiswamy PM, Xu R Alzheimer's research & therapy 34670619 Alzheimers Res Ther 2021 Oct 20 https://www.ncbi.nlm.nih.gov/pubmed/34670619
Predict Alzheimer's disease using hippocampus MRI data: a lightweight 3D deep convolutional network model with visual and global shape representations. Katabathula S, Wang Q, Xu R Alzheimer's research & therapy 34030743 Alzheimers Res Ther 2021 May 24 https://www.ncbi.nlm.nih.gov/pubmed/34030743
DenseCNN: A Densely Connected CNN Model for Alzheimer's Disease Classification Based on Hippocampus MRI Data. Wang Q, Li Y, Zheng C, Xu R AMIA ... Annual Symposium proceedings. AMIA Symposium 33936504 AMIA Annu Symp Proc 2020 https://www.ncbi.nlm.nih.gov/pubmed/33936504
COVID-19 risk and outcomes in patients with substance use disorders: analyses from electronic health records in the United States. Wang QQ, Kaelber DC, Xu R, Volkow ND Molecular psychiatry 32929211 Mol Psychiatry 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/32929211
Data-driven multiple-level analysis of gut-microbiome-immune-joint interactions in rheumatoid arthritis. Wang Q, Xu R BMC genomics 30744546 BMC Genomics 2019 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/30744546
A semi-supervised approach to extract pharmacogenomics-specific drug-gene pairs from biomedical literature for personalized medicine. Xu R, Wang Q Journal of biomedical informatics 23570835 J Biomed Inform 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23570835
An iterative searching and ranking algorithm for prioritising pharmacogenomics genes. Xu R, Wang Q International journal of computational biology and drug design 23428471 Int J Comput Biol Drug Des 2013 https://www.ncbi.nlm.nih.gov/pubmed/23428471
Automatic signal extraction, prioritizing and filtering approaches in detecting post-marketing cardiovascular events associated with targeted cancer drugs from the FDA Adverse Event Reporting System (FAERS). Xu R, Wang Q Journal of biomedical informatics 24177320 J Biomed Inform 2014 Feb https://www.ncbi.nlm.nih.gov/pubmed/24177320
Towards understanding brain-gut-microbiome connections in Alzheimer's disease. Xu R, Wang Q BMC systems biology 27585440 BMC Syst Biol 2016 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/27585440
The Alzheimer's comorbidity phenome: mining from a large patient database and phenome-driven genetics prediction. Zheng C, Xu R JAMIA open 30944912 JAMIA Open 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30944912
Molecular subtyping of Alzheimer's disease with consensus non-negative matrix factorization. Zheng C, Xu R PloS one 34014928 PLoS One 2021 https://www.ncbi.nlm.nih.gov/pubmed/34014928
Large-scale mining disease comorbidity relationships from post-market drug adverse events surveillance data. Zheng C, Xu R BMC bioinformatics 30591027 BMC Bioinformatics 2018 Dec 28 https://www.ncbi.nlm.nih.gov/pubmed/30591027
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Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-Thioguanosine. Kiefer L, Schofield JA, Simon MD Journal of the American Chemical Society 30353734 J Am Chem Soc 2018 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/30353734
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Catching RNAs on chromatin using hybridization capture methods. Machyna M, Simon MD Briefings in functional genomics 29126220 Brief Funct Genomics 2018 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/29126220
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Population Intervention Measures to Connect Research Findings to Policy. Ahern J American journal of public health 27831772 Am J Public Health 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27831772
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Preliminary Experiments with a Unified Controller for a Powered Knee-Ankle Prosthetic Leg Across Walking Speeds. Quintero D, Villarreal DJ, Gregg RD Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems 28392969 Rep U S 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/28392969
Unified Phase Variables of Relative Degree Two for Human Locomotion. Villarreal DJ, Gregg RD Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 28261013 Annu Int Conf IEEE Eng Med Biol Soc 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/28261013
Decentralized Feedback Controllers for Exponential Stabilization of Hybrid Periodic Orbits: Application to Robotic Walking. Hamed KA, Gregg RD Proceedings of the ... American Control Conference. American Control Conference 27990059 Proc Am Control Conf 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27990059
Decentralized Passivity-Based Control With a Generalized Energy Storage Function for Robust Biped Locomotion. Yeatman M, Lv G, Gregg RD Journal of dynamic systems, measurement, and control 31666751 J Dyn Syst Meas Control 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31666751
Experimental Implementation of Underactuated Potential Energy Shaping on a Powered Ankle-Foot Orthosis. Lv G, Zhu H, Elery T, Li L, Gregg RD IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation 27390625 IEEE Int Conf Robot Autom 2016 May https://www.ncbi.nlm.nih.gov/pubmed/27390625
Towards Total Energy Shaping Control of Lower-Limb Exoskeletons. Lv G, Gregg RD Proceedings of the ... American Control Conference. American Control Conference 29104363 Proc Am Control Conf 2017 May https://www.ncbi.nlm.nih.gov/pubmed/29104363
Underactuated Potential Energy Shaping with Contact Constraints: Application to a Powered Knee-Ankle Orthosis. Lv G, Gregg RD IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society 29398885 IEEE Trans Control Syst Technol 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29398885
Stable, Robust Hybrid Zero Dynamics Control of Powered Lower-Limb Prostheses. Martin AE, Gregg RD IEEE transactions on automatic control 29276305 IEEE Trans Automat Contr 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/29276305
Real-Time Continuous Gait Phase and Speed Estimation from a Single Sensor. Quintero D, Lambert DJ, Villarreal DJ, Gregg RD Control Technology and Applications. Control Technology and Applications 30148285 Control Technol Appl 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/30148285
Modeling the Kinematics of Human Locomotion Over Continuously Varying Speeds and Inclines. Embry KR, Villarreal DJ, Macaluso RL, Gregg RD IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society 30403633 IEEE Trans Neural Syst Rehabil Eng 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30403633
A survey of phase variable candidates of human locomotion. Villarreal DJ, Gregg RD Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 25570873 Annu Int Conf IEEE Eng Med Biol Soc 2014 https://www.ncbi.nlm.nih.gov/pubmed/25570873
Design and Validation of a Partial-Assist Knee Orthosis with Compact, Backdrivable Actuation. Zhu H, Nesler C, Divekar N, Ahmad MT, Gregg RD IEEE ... International Conference on Rehabilitation Robotics : [proceedings] 31374747 IEEE Int Conf Rehabil Robot 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31374747
Hybrid Nonlinear Disturbance Observer Design for Underactuated Bipedal Robots. Mohammadi A, Fakoorian S, Horn JC, Simon D, Gregg RD Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control 30778276 Proc IEEE Conf Decis Control 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30778276
A Phase Variable Approach for Improved Rhythmic and Non-Rhythmic Control of a Powered Knee-Ankle Prosthesis. Rezazadeh S, Quintero D, Divekar N, Reznick E, Gray L, Gregg RD IEEE access : practical innovations, open solutions 31656719 IEEE Access 2019 https://www.ncbi.nlm.nih.gov/pubmed/31656719
A Perturbation Mechanism for Investigations of Phase Variables in Human Locomotion. Villarreal DJ, Quintero D, Gregg RD ... IEEE International Conference on Robotics and Biomimetics. IEEE International Conference on Robotics and Biomimetics 27158684 IEEE ROBIO 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/27158684
A Robust Parameterization of Human Gait Patterns Across Phase-Shifting Perturbations. Villarreal DJ, Poonawala HA, Gregg RD IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society 27187967 IEEE Trans Neural Syst Rehabil Eng 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/27187967
A Control Framework for Anthropomorphic Biped Walking Based on Stabilizing Feedforward Trajectories. Rezazadeh S, Gregg RD Proceedings of the ASME Dynamic Systems and Control Conference. ASME Dynamic Systems and Control Conference 28239504 Proc ASME Dyn Syst Control Conf 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/28239504
Design and Benchtop Validation of a Powered Knee-Ankle Prosthesis with High-Torque, Low-Impedance Actuators. Elery T, Rezazadeh S, Nesler C, Doan J, Zhu H, Gregg RD IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation 30598854 IEEE Int Conf Robot Autom 2018 May https://www.ncbi.nlm.nih.gov/pubmed/30598854
Automatic Tuning of Virtual Constraint-Based Control Algorithms for Powered Knee-Ankle Prostheses. Kumar S, Mohammadi A, Gans N, Gregg RD Control Technology and Applications. Control Technology and Applications 30175324 Control Technol Appl 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/30175324
Piecewise and unified phase variables in the control of a powered prosthetic leg. Villarreal DJ, Quintero D, Gregg RD IEEE ... International Conference on Rehabilitation Robotics : [proceedings] 28814020 IEEE Int Conf Rehabil Robot 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28814020
Extremum Seeking Control for Model-Free Auto-Tuning of Powered Prosthetic Legs. Kumar S, Mohammadi A, Quintero D, Rezazadeh S, Gans N, Gregg RD IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society 33041615 IEEE Trans Control Syst Technol 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/33041615
Design and Validation of a Powered Knee-Ankle Prosthesis with High-Torque, Low-Impedance Actuators. Elery T, Rezazadeh S, Nesler C, Gregg RD IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society 33299386 IEEE Trans Robot 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33299386
Prosthetic Leg Control in the Nullspace of Human Interaction. Gregg RD, Martin AE Proceedings of the ... American Control Conference. American Control Conference 27746585 Proc Am Control Conf 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27746585
A GENERAL FRAMEWORK FOR MINIMIZING ENERGY CONSUMPTION OF SERIES ELASTIC ACTUATORS WITH REGENERATION. Bolívar E, Rezazadeh S, Gregg R Proceedings of the ASME Dynamic Systems and Control Conference. ASME Dynamic Systems and Control Conference 29170721 Proc ASME Dyn Syst Control Conf 2017 https://www.ncbi.nlm.nih.gov/pubmed/29170721
Incorporating Human-like Walking Variability in an HZD-Based Bipedal Model. Martin AE, Gregg RD IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society 28082836 IEEE Trans Robot 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/28082836
A Unified Parameterization of Human Gait Across Ambulation Modes. Embry KR, Villarreal DJ, Gregg RD Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 28261005 Annu Int Conf IEEE Eng Med Biol Soc 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/28261005
Decentralized Feedback Controllers for Robust Stabilization of Periodic Orbits of Hybrid Systems: Application to Bipedal Walking. Hamed KA, Gregg RD IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society 28959117 IEEE Trans Control Syst Technol 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28959117
A Perturbation Mechanism for Investigations of Phase-Dependent Behavior in Human Locomotion. Villarreal DJ, Quintero D, Gregg RD IEEE access : practical innovations, open solutions 27570719 IEEE Access 2016 https://www.ncbi.nlm.nih.gov/pubmed/27570719
Hybrid Invariance and Stability of a Feedback Linearizing Controller for Powered Prostheses. Martin AE, Gregg RD Proceedings of the ... American Control Conference. American Control Conference 26604427 Proc Am Control Conf 2015 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/26604427
Intuitive Clinician Control Interface for a Powered Knee-Ankle Prosthesis: A Case Study. Quintero D, Reznick E, Lambert DJ, Rezazadeh S, Gray L, Gregg RD IEEE journal of translational engineering in health and medicine 30546971 IEEE J Transl Eng Health Med 2018 https://www.ncbi.nlm.nih.gov/pubmed/30546971
Virtual Constraint Control of a Powered Prosthetic Leg: From Simulation to Experiments with Transfemoral Amputees. Gregg RD, Lenzi T, Hargrove LJ, Sensinger JW IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society 25558185 IEEE Trans Robot 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25558185
Variable Impedance Control of Powered Knee Prostheses Using Human-Inspired Algebraic Curves. Mohammadi A, Gregg RD Journal of computational and nonlinear dynamics 32280314 J Comput Nonlinear Dyn 2019 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/32280314
Design and Validation of a Torque Dense, Highly Backdrivable Powered Knee-Ankle Orthosis. Zhu H, Doan J, Stence C, Lv G, Elery T, Gregg R IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation 29057142 IEEE Int Conf Robot Autom 2017 May-Jun https://www.ncbi.nlm.nih.gov/pubmed/29057142
A Phase Variable Approach to Volitional Control of Powered Knee-Ankle Prostheses. Rezazadeh S, Quintero D, Divekar N, Gregg RD Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems 30746286 Rep U S 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30746286
Design Principles for Compact, Backdrivable Actuation in Partial-Assist Powered Knee Orthoses. Zhu H, Nesler C, Divekar N, Peddinti V, Gregg RD IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division 34916771 IEEE ASME Trans Mechatron 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34916771
Evidence for a time-invariant phase variable in human ankle control. Gregg RD, Rouse EJ, Hargrove LJ, Sensinger JW PloS one 24558485 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/24558485
Orthotic Body-Weight Support Through Underactuated Potential Energy Shaping with Contact Constraints. Lv G, Gregg RD Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control 26900254 Proc IEEE Conf Decis Control 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26900254
Unifying the Gait Cycle in the Control of a Powered Prosthetic Leg. Quintero D, Martin AE, Gregg RD IEEE ... International Conference on Rehabilitation Robotics : [proceedings] 26913092 IEEE Int Conf Rehabil Robot 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26913092
SIMULTANEOUS CONTROL OF AN ANKLE-FOOT PROSTHESIS MODEL USING A VIRTUAL CONSTRAINT. Nanjangud A, Gregg RD Proceedings of the ASME Dynamic Systems and Control Conference. ASME Dynamic Systems and Control Conference 25554734 Proc ASME Dyn Syst Control Conf 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25554734
Characterizing and modeling the joint-level variability in human walking. Martin AE, Villarreal DJ, Gregg RD Journal of biomechanics 27594679 J Biomech 2016 Oct 3 https://www.ncbi.nlm.nih.gov/pubmed/27594679
Minimizing Energy Consumption and Peak Power of Series Elastic Actuators: A Convex Optimization Framework for Elastic Element Design. Bolívar Nieto EA, Rezazadeh S, Gregg RD 4th IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division 31649476 IEEE ASME Trans Mechatron 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31649476
Robust Optimal Design of Energy Efficient Series Elastic Actuators: Application to a Powered Prosthetic Ankle. Bolivar E, Rezazadeh S, Summers T, Gregg RD IEEE ... International Conference on Rehabilitation Robotics : [proceedings] 31374719 IEEE Int Conf Rehabil Robot 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31374719
Removing Phase Variables from Biped Robot Parametric Gaits. Mohammadi A, Horn J, Gregg RD Control Technology and Applications. Control Technology and Applications 30198027 Control Technol Appl 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/30198027
On the Design and Control of Highly Backdrivable Lower-Limb Exoskeletons: A Discussion of Past and Ongoing Work. Lv G, Zhu H, Gregg RD IEEE control systems 30598586 IEEE Control Syst 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30598586
Parameterizing Human Locomotion Across Quasi-Random Treadmill Perturbations and Inclines. Macaluso R, Embry K, Villarreal DJ, Gregg RD IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society 33556013 IEEE Trans Neural Syst Rehabil Eng 2021 https://www.ncbi.nlm.nih.gov/pubmed/33556013
Toward Unified Control of a Powered Prosthetic Leg: A Simulation Study. Quintero D, Martin AE, Gregg RD IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society 29403259 IEEE Trans Control Syst Technol 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29403259
Passivity-Based Control with a Generalized Energy Storage Function for Robust Walking of Biped Robots. Yeatman MR, Lv G, Gregg RD Proceedings of the ... American Control Conference. American Control Conference 30220783 Proc Am Control Conf 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/30220783
Continuous-Phase Control of a Powered Knee-Ankle Prosthesis: Amputee Experiments Across Speeds and Inclines. Quintero D, Villarreal DJ, Lambert DJ, Kapp S, Gregg RD IEEE transactions on robotics : a publication of the IEEE Robotics and Automation Society 30008623 IEEE Trans Robot 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/30008623
A Haptic Feedback System for Phase-Based Sensory Restoration in Above-Knee Prosthetic Leg Users. Plauche A, Villarreal D, Gregg RD IEEE transactions on haptics 27323375 IEEE Trans Haptics 2016 Jul-Sep https://www.ncbi.nlm.nih.gov/pubmed/27323375
HUMAN-INSPIRED ALGEBRAIC CURVES FOR WEARABLE ROBOT CONTROL. Mohammadi A, Gregg RD Proceedings of the ASME Dynamic Systems and Control Conference. ASME Dynamic Systems and Control Conference 30906619 Proc ASME Dyn Syst Control Conf 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30906619
Engineering immunity in the mucosal niche against sexually transmitted infections. Ramanathan R, Woodrow K Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 26153141 Wiley Interdiscip Rev Nanomed Nanobiotechnol 2016 Jan-Feb https://www.ncbi.nlm.nih.gov/pubmed/26153141
Effect of Mucosal Cytokine Administration on Selective Expansion of Vaginal Dendritic Cells to Support Nanoparticle Transport. Ramanathan R, Park J, Hughes SM, Lykins WR, Bennett HR, Hladik F, Woodrow KA American journal of reproductive immunology (New York, N.Y. : 1989) 26118309 Am J Reprod Immunol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26118309
Microneedle-Mediated Vaccine Delivery to the Oral Mucosa. Creighton RL, Woodrow KA Advanced healthcare materials 30537400 Adv Healthc Mater 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30537400
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Chitosan enhances nanoparticle delivery from the reproductive tract to target draining lymphoid organs. Park J, Ramanathan R, Pham L, Woodrow KA Nanomedicine : nanotechnology, biology, and medicine 28435136 Nanomedicine 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28435136
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Ragweed pollen as an oral vaccine delivery system: Mechanistic insights. Uddin MJ, Gill HS Journal of controlled release : official journal of the Controlled Release Society 29054371 J Control Release 2017 Dec 28 https://www.ncbi.nlm.nih.gov/pubmed/29054371
From allergen to oral vaccine carrier: A new face of ragweed pollen. Uddin MJ, Gill HS International journal of pharmaceutics 29729407 Int J Pharm 2018 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/29729407
Role of Sporopollenin Shell Interfacial Properties in Protein Adsorption. Uddin MJ, Liyanage S, Warzywoda J, Abidi N, Gill HS Langmuir : the ACS journal of surfaces and colloids 35212551 Langmuir 2022 Mar 8 https://www.ncbi.nlm.nih.gov/pubmed/35212551
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Comparative profiling of cellular gait on adhesive micropatterns defines statistical patterns of activity that underlie native and cancerous cell dynamics. Ahn JC, Coyle SM bioRxiv : the preprint server for biology 37961146 bioRxiv 2023 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/37961146
A programmable reaction-diffusion system for spatiotemporal cell signaling circuit design. Rajasekaran R, Chang CC, Weix EWZ, Galateo TM, Coyle SM Cell 38181787 Cell 2024 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/38181787
Synthetic forms most beautiful: engineering insights into self-organization. Xu Z, Chang CC, Coyle S Physiology (Bethesda, Md.) 39938118 Physiology (Bethesda) 2025 Feb 12 https://www.ncbi.nlm.nih.gov/pubmed/39938118
Genetically encoded protein oscillators for FM streaming of single-cell data. Rajasekaran R, Galateo TM, Xu Z, Bolshakov DT, Weix EWZ, Coyle SM bioRxiv : the preprint server for biology 40060462 bioRxiv 2025 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/40060462
Regulatable assembly of synthetic microtubule architectures using engineered MAP-IDR condensates. Chang CC, Coyle SM bioRxiv : the preprint server for biology 38105997 bioRxiv 2023 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/38105997
A mitochondrial redox switch licenses the onset of morphogenesis in animals. Kahlon U, Ricca FD, Pillai SJ, Olivetta M, Tharp KM, Jao LE, Dudin O, McDonald K, Aydogan MG bioRxiv : the preprint server for biology 39553983 bioRxiv 2024 Oct 29 https://www.ncbi.nlm.nih.gov/pubmed/39553983
Cytoplasmic division cycles without the nucleus and mitotic CDK/cyclin complexes. Bakshi A, Iturra FE, Alamban A, Rosas-Salvans M, Dumont S, Aydogan MG Cell 37832525 Cell 2023 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/37832525
Dissecting host-microbe interactions with modern functional genomics. Russell BJ, Verma M, Maier NK, Jost M Current opinion in microbiology 39368241 Curr Opin Microbiol 2024 Dec https://www.ncbi.nlm.nih.gov/pubmed/39368241
Nonpathogenic E. coli engineered to surface display cytokines as a new platform for immunotherapy. Yang S, Sheffer M, Kaplan IE, Wang Z, Tarannum M, Dinh K, Abdulhamid Y, Shapiro R, Porter R, Soiffer R, Ritz J, Koreth J, Wei Y, Chen P, Zhang K, Márquez-Pellegrin V, Bonanno S, Joshi N, Guan M, Yang M, Li D, Bellini C, Chen J, Wu CJ, Barbie D, Li J, Romee R Research square 38562821 Res Sq 2024 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/38562821
A New Bacterial Chassis for Enhanced Surface Display of Recombinant Proteins. Zhang R, Ye N, Wang Z, Yang S, Li J Cellular and molecular bioengineering 39513006 Cell Mol Bioeng 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/39513006
Engineering Tripartite Gene Editing Machinery for Highly Efficient Non-Viral Targeted Genome Integration. Nam H, Xie K, Majumdar I, Yang S, Starzyk J, Lee D, Shan R, Li J, Wu H Research square 37961210 Res Sq 2023 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/37961210
Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses. Yang S, Sheffer M, Kaplan IE, Wang Z, Tarannum M, Dinh K, Abdulhamid Y, Bobilev E, Shapiro R, Porter R, Soiffer R, Ritz J, Koreth J, Wei Y, Chen P, Zhang K, Márquez-Pellegrin V, Bonanno S, Joshi N, Guan M, Yang M, Li D, Bellini C, Liu F, Chen J, Wu CJ, Barbie D, Li J, Romee R Nature biotechnology 39367093 Nat Biotechnol 2024 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/39367093
Squeezable Hydrogel Microparticles for Single Extracellular Vesicle Protein Profiling. Roh YH, Morales RT, Huynh E, Chintapula U, Reynolds DE, Agosto-Nieves RJ, Oh D, Seiner AJ, Lim J, Rodell CB, Ko J Small (Weinheim an der Bergstrasse, Germany) 39468876 Small 2025 Jan https://www.ncbi.nlm.nih.gov/pubmed/39468876
Targeted protein relocalization via protein transport coupling. Ng CSC, Liu A, Cui B, Banik SM Nature 39294374 Nature 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/39294374
Self-Assembled Nanocoatings Protect Microbial Fertilizers for Climate-Resilient Agriculture. Burke B, Fan G, Wasuwanich P, Moore EB, Furst AL JACS Au 38034965 JACS Au 2023 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/38034965
Transferrin receptor targeting chimeras for membrane protein degradation. Zhang D, Duque-Jimenez J, Facchinetti F, Brixi G, Rhee K, Feng WW, Jänne PA, Zhou X Nature 39322661 Nature 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39322661
A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA. Ranzau BL, Robinson TD, Scully JM, Kapelczak ED, Dean TS, TeSlaa T, Schmitt DL ACS bio & med chem Au 39990938 ACS Bio Med Chem Au 2025 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/39990938
A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA. Ranzau BL, Robinson TD, Scully JM, Kapelczack ED, Dean TS, TeSlaa T, Schmitt DL bioRxiv : the preprint server for biology 39386450 bioRxiv 2024 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/39386450
Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability. Bai D, Cao Z, Attada N, Song J, Zhu C Nature methods 40128288 Nat Methods 2025 Mar 24 https://www.ncbi.nlm.nih.gov/pubmed/40128288
A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction. Li X, Gamuyao R, Wu ML, Cho WJ, Kurtz NB, King SV, Petersen RA, Stabley DR, Lindow C, Climer L, Shirinifard A, Ferrara F, Throm RE, Robinson CG, Carisey A, Tebo AG, Chang CL bioRxiv : the preprint server for biology 38076863 bioRxiv 2023 Nov 29 https://www.ncbi.nlm.nih.gov/pubmed/38076863
A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction. Li X, Gamuyao R, Wu ML, Cho WJ, King SV, Petersen RA, Stabley DR, Lindow C, Climer LK, Shirinifard A, Ferrara F, Throm RE, Robinson CG, Zhou Y, Carisey AF, Tebo AG, Chang CL The Journal of cell biology 38949658 J Cell Biol 2024 Sep 2 https://www.ncbi.nlm.nih.gov/pubmed/38949658
Models for human telomere C-strand fill-in by CST-Polα-primase. He Q, Lim CJ Trends in biochemical sciences 37586999 Trends Biochem Sci 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/37586999
Small LEA proteins as an effective air-water interface protectant for fragile samples during cryo-EM grid plunge freezing. Abe KM, Lim CJ bioRxiv : the preprint server for biology 38370693 bioRxiv 2024 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/38370693
Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing. Abe KM, Li G, He Q, Grant T, Lim CJ Nature communications 39231985 Nat Commun 2024 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/39231985
MitoTNT: Mitochondrial Temporal Network Tracking for 4D live-cell fluorescence microscopy data. Wang Z, Natekar P, Tea C, Tamir S, Hakozaki H, Schöneberg J PLoS computational biology 37083820 PLoS Comput Biol 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/37083820
LiveLattice: Real-time visualization of tilted light-sheet microscopy data using a memory-efficient transformation algorithm. Wang Z, Hakozaki H, McMahon G, Medina-Carbonero M, Schöneberg J bioRxiv : the preprint server for biology 38854017 bioRxiv 2024 May 30 https://www.ncbi.nlm.nih.gov/pubmed/38854017
LiveLattice: Real-time visualisation of tilted light-sheet microscopy data using a memory-efficient transformation algorithm. Wang Z, Hakozaki H, McMahon G, Medina-Carbonero M, Schöneberg J Journal of microscopy 39360400 J Microsc 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39360400
OpenTn5: Open-Source Resource for Robust and Scalable Tn5 Transposase Purification and Characterization. Soroczynski J, Anderson LJ, Yeung JL, Rendleman JM, Oren DA, Konishi HA, Risca VI bioRxiv : the preprint server for biology 39026714 bioRxiv 2024 Jul 13 https://www.ncbi.nlm.nih.gov/pubmed/39026714
Determining mesoscale chromatin structure parameters from spatially correlated cleavage data using a coarse-grained oligonucleosome model. Clerkin AB, Pagane N, West DW, Spakowitz AJ, Risca VI bioRxiv : the preprint server for biology 39131347 bioRxiv 2024 Jul 29 https://www.ncbi.nlm.nih.gov/pubmed/39131347
A nucleosome switch primes Hepatitis B Virus infection. Prescott NA, Mansisidor A, Bram Y, Biaco T, Rendleman J, Faulkner SC, Lemmon AA, Lim C, Hamard PJ, Koche RP, Risca VI, Schwartz RE, David Y bioRxiv : the preprint server for biology 38915612 bioRxiv 2024 Jun 12 https://www.ncbi.nlm.nih.gov/pubmed/38915612
Technological advances in probing 4D genome organization. Soroczynski J, Risca VI Current opinion in cell biology 37556867 Curr Opin Cell Biol 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/37556867
Chromatin accessibility: methods, mechanisms, and biological insights. Mansisidor AR, Risca VI Nucleus (Austin, Tex.) 36404679 Nucleus 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36404679
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III. Chen B, Stark DC, Jadhav PV, Lynn-Nguyen TM, Halligan BS, Rossiter NJ, Sindoni N, Shin M, Paulo JA, Chang M, Koo I, Koshkin S, Eyunni S, Ronchi P, Paulsen MT, Morlacchi P, Hanna DA, Lin J, Guerra RM, Pagliarini DJ, Banerjee R, Parolia A, Ljungman ME, Patterson AD, Mancias JD, Mosalaganti S, Sexton JZ, Calì T, Lyssiotis CA, Shah YM bioRxiv : the preprint server for biology 38352460 bioRxiv 2024 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/38352460
Rapid structural analysis of bacterial ribosomes in situ. Powell BM, Brant TS, Davis JH, Mosalaganti S Communications biology 39875527 Commun Biol 2025 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/39875527
Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT). Navratna V, Kumar A, Rana JK, Mosalaganti S bioRxiv : the preprint server for biology 37961489 bioRxiv 2024 Jun 12 https://www.ncbi.nlm.nih.gov/pubmed/37961489
Rapid structural analysis of bacterial ribosomes in situ. Powell BM, Brant TS, Davis JH, Mosalaganti S bioRxiv : the preprint server for biology 38585831 bioRxiv 2024 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/38585831
Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain. Navratna V, Kumar A, Rana JK, Mosalaganti S Life science alliance 38925866 Life Sci Alliance 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/38925866
Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT). Navratna V, Kumar A, Rana JK, Mosalaganti S eLife 39196614 Elife 2024 Aug 28 https://www.ncbi.nlm.nih.gov/pubmed/39196614
Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain. Navratna V, Kumar A, Rana JK, Mosalaganti S bioRxiv : the preprint server for biology 38187772 bioRxiv 2024 Jun 12 https://www.ncbi.nlm.nih.gov/pubmed/38187772
Molecular Visualization of Neuronal TDP43 Pathology In Situ. Erwin AL, Chang ML, Fernandez MG, Attili D, Russ JE, Sutanto R, Pinarbasi ES, Bekier M, Brant TS, Hahn T, Dykstra M, Thomas D, Li X, Baldridge RD, Tank EMH, Barmada SJ, Mosalaganti S bioRxiv : the preprint server for biology 39229019 bioRxiv 2024 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/39229019
LiFT (a Lithium Fiber-Based Test): An At-Home Companion Diagnostics for a Safer Lithium Therapy in Bipolar Disorder. Amirghasemi F, Nejad SK, Chen R, Soleimani A, Ong V, Shroff N, Eftekhari T, Ushijima K, Ainla A, Siegel S, Mousavi MPS Advanced healthcare materials 38563494 Adv Healthc Mater 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38563494
Flexible Acetylcholine Neural Probe with a Hydrophobic Laser-Induced Graphene Electrode and a Fluorous-Phase Sensing Membrane. Amirghasemi F, Al-Shami A, Ushijima K, Mousavi MPS ACS materials letters 39309214 ACS Mater Lett 2024 Sep 2 https://www.ncbi.nlm.nih.gov/pubmed/39309214
Towards sustainable and humane dairy farming: A low-cost electrochemical sensor for on-site diagnosis of milk fever. Soleimani A, Amirghasemi F, Al-Shami A, Khazaee Nejad S, Tsung A, Wang Y, Lara Galindo S, Parvin D, Olson A, Avishai A, Mousavi MPS Biosensors & bioelectronics 38749287 Biosens Bioelectron 2024 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/38749287
SPOOC (Sensor for Periodic Observation of Choline): An Integrated Lab-on-a-Spoon Platform for At-Home Quantification of Choline in Infant Formula. Al-Shami A, Amirghasemi F, Soleimani A, Khazaee Nejad S, Ong V, Berkmen A, Ainla A, Mousavi MPS Small (Weinheim an der Bergstrasse, Germany) 38587168 Small 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38587168
Toward Personalized Treatment of Depression: An Affordable Citalopram Test based on a Solid-Contact Potentiometric Electrode for at-Home Monitoring of the Antidepressant Dosage. Chen R, Amirghasemi F, Ma H, Ong V, Tran A, Mousavi MPS ACS sensors 37734027 ACS Sens 2023 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/37734027
Lab-on-a-lollipop (LoL) platform for preventing food-induced toxicity: all-in-one system for saliva sampling and electrochemical detection of vanillin. Ma H, Khazaee Nejad S, Vargas Ramos D, Al-Shami A, Soleimani A, Amirghasemi F, Mohamed MA, Mousavi MPS Lab on a chip 39207360 Lab Chip 2024 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/39207360
Expansion microscopy: A chemical approach for super-resolution microscopy. Zhuang Y, Shi X Current opinion in structural biology 37253290 Curr Opin Struct Biol 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37253290
RBBP6 anchors pre-mRNA 3' end processing to nuclear speckles for efficient gene expression. Yoon Y, Bournique E, Soles LV, Yin H, Chu HF, Yin C, Zhuang Y, Liu X, Liu L, Jeong J, Yu C, Valdez M, Tian L, Huang L, Shi X, Seelig G, Ding F, Tong L, Buisson R, Shi Y Molecular cell 39798570 Mol Cell 2025 Feb 6 https://www.ncbi.nlm.nih.gov/pubmed/39798570
Cationic peptides erase memories by removing synaptic AMPA receptors through endophilin-mediated endocytosis. Stokes E, Zhuang Y, Toledano M, Vasquez J, Azouz G, Hui M, Tyler I, Shi X, Aoto J, Beier KT Research square 38045269 Res Sq 2023 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/38045269
Label-Retention Expansion Microscopy (LR-ExM) for Enhanced Fluorescent Signals using Trifunctional Probes. Zhuang Y, Shi X Current protocols 38265180 Curr Protoc 2024 Jan https://www.ncbi.nlm.nih.gov/pubmed/38265180
Proximity labeling expansion microscopy (PL-ExM) evaluates interactome labeling techniques. Park S, Wang X, Mo Y, Zhang S, Li X, Fong KC, Yu C, Tran AA, Scipioni L, Dai Z, Huang X, Huang L, Shi X Journal of materials chemistry. B 39105364 J Mater Chem B 2024 Aug 28 https://www.ncbi.nlm.nih.gov/pubmed/39105364
Proximity Labeling Expansion Microscopy (PL-ExM) resolves structure of the interactome. Park S, Wang X, Li X, Huang X, Fong KC, Yu C, Tran AA, Scipioni L, Dai Z, Huang L, Shi X bioRxiv : the preprint server for biology 38014020 bioRxiv 2023 Nov 13 https://www.ncbi.nlm.nih.gov/pubmed/38014020
Coaching ribosome biogenesis from the nuclear periphery. Zhuang Y, Guo X, Razorenova OV, Miles CE, Zhao W, Shi X bioRxiv : the preprint server for biology 38948754 bioRxiv 2024 Jun 22 https://www.ncbi.nlm.nih.gov/pubmed/38948754
Enhanced dynamic coupling in a nuclear receptor underlies ligand activity. Yu T, Villalona P, Khan SH, Mikeasky N, Meinert E, Magafas J, Pulahinge T, Bader A, Okafor CD The Journal of biological chemistry 39675705 J Biol Chem 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39675705
Phase Separation in Biology and Disease; Current Perspectives and Open Questions. Boeynaems S, Chong S, Gsponer J, Holt L, Milovanovic D, Mitrea DM, Mueller-Cajar O, Portz B, Reilly JF, Reinkemeier CD, Sabari BR, Sanulli S, Shorter J, Sontag E, Strader L, Stachowiak J, Weber SC, White M, Zhang H, Zweckstetter M, Elbaum-Garfinkle S, Kriwacki R Journal of molecular biology 36690068 J Mol Biol 2023 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/36690068
Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection. Abdullah L, Emiliani FE, Vaidya CM, Stuart H, Kolling FW, Ackerman ME, Song L, McKenna A, Huang YH bioRxiv : the preprint server for biology 38585810 bioRxiv 2024 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/38585810
The endogenous antigen-specific CD8(+) T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments. Abdullah L, Emiliani FE, Vaidya CM, Stuart H, Musial SC, Kolling FW, Obar JJ, Rosato PC, Ackerman ME, Song L, McKenna A, Huang YH Immunity 40020673 Immunity 2025 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/40020673
Programmability and biomedical utility of intrinsically-disordered protein polymers. Giraldo-Castaño MC, Littlejohn KA, Avecilla ARC, Barrera-Villamizar N, Quiroz FG Advanced drug delivery reviews 39094909 Adv Drug Deliv Rev 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/39094909
Genetically-encoded phase separation sensors for intracellular probing of biomolecular condensates. Regina Chua Avecilla A, Thomas J, Quiroz FG bioRxiv : the preprint server for biology 39257779 bioRxiv 2024 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/39257779
Genetically-Encoded Phase Separation Sensors Enable High-Fidelity Live-Cell Probing of Biomolecular Condensates. Avecilla ARC, Thomas J, Quiroz FG ACS sensors 39987501 ACS Sens 2025 Mar 28 https://www.ncbi.nlm.nih.gov/pubmed/39987501
Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning. Laubscher E, Wang XJ, Razin N, Dougherty T, Xu RJ, Ombelets L, Pao E, Graf W, Moffitt JR, Yue Y, Van Valen D bioRxiv : the preprint server for biology 37732188 bioRxiv 2024 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/37732188
Generalized cell phenotyping for spatial proteomics with language-informed vision models. Wang XJ, Dilip R, Bussi Y, Brown C, Pradhan E, Jain Y, Yu K, Li S, Abt M, Börner K, Keren L, Yue Y, Barnowski R, Van Valen D bioRxiv : the preprint server for biology 39605651 bioRxiv 2024 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/39605651
CellSAM: A Foundation Model for Cell Segmentation. Israel U, Marks M, Dilip R, Li Q, Yu C, Laubscher E, Iqbal A, Pradhan E, Ates A, Abt M, Brown C, Pao E, Li S, Pearson-Goulart A, Perona P, Gkioxari G, Barnowski R, Yue Y, Van Valen D bioRxiv : the preprint server for biology 38045277 bioRxiv 2025 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/38045277
A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation. Yanchus C, Drucker KL, Kollmeyer TM, Tsai R, Winick-Ng W, Liang M, Malik A, Pawling J, De Lorenzo SB, Ali A, Decker PA, Kosel ML, Panda A, Al-Zahrani KN, Jiang L, Browning JWL, Lowden C, Geuenich M, Hernandez JJ, Gosio JT, Ahmed M, Loganathan SK, Berman J, Trcka D, Michealraj KA, Fortin J, Carson B, Hollingsworth EW, Jacinto S, Mazrooei P, Zhou L, Elia A, Lupien M, He HH, Murphy DJ, Wang L, Abyzov A, Dennis JW, Maass PG, Campbell K, Wilson MD, Lachance DH, Wrensch M, Wiencke J, Mak T, Pennacchio LA, Dickel DE, Visel A, Wrana J, Taylor MD, Zadeh G, Dirks P, Eckel-Passow JE, Attisano L, Pombo A, Ida CM, Kvon EZ, Jenkins RB, Schramek D Science (New York, N.Y.) 36201590 Science 2022 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/36201590
Conserved Cis-Acting Range Extender Element Mediates Extreme Long-Range Enhancer Activity in Mammals. Bower G, Hollingsworth EW, Jacinto S, Clock B, Cao K, Liu M, Dziulko A, Alcaina-Caro A, Xu Q, Skowronska-Krawczyk D, Lopez-Rios J, Dickel DE, Bardet AF, Pennacchio LA, Visel A, Kvon EZ bioRxiv : the preprint server for biology 38826394 bioRxiv 2024 May 26 https://www.ncbi.nlm.nih.gov/pubmed/38826394
Genetic factors mediating long-range enhancer-promoter communication in mammalian development. Bower G, Kvon EZ Current opinion in genetics & development 39579740 Curr Opin Genet Dev 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39579740
Increased enhancer-promoter interactions during developmental enhancer activation in mammals. Chen Z, Snetkova V, Bower G, Jacinto S, Clock B, Dizehchi A, Barozzi I, Mannion BJ, Alcaina-Caro A, Lopez-Rios J, Dickel DE, Visel A, Pennacchio LA, Kvon EZ Nature genetics 38509385 Nat Genet 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38509385
Rapid and Quantitative Functional Interrogation of Human Enhancer Variant Activity in Live Mice. Hollingsworth EW, Liu TA, Jacinto SH, Chen CX, Alcantara JA, Kvon EZ bioRxiv : the preprint server for biology 38105996 bioRxiv 2023 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/38105996
Protocol for building a user-friendly temperature control system to support microscopes, microfluidic chambers, and custom incubators. Liu Z, Nguyen TTT, Ding F STAR protocols 38294908 STAR Protoc 2024 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/38294908
Cost-efficient boundary-free surface patterning achieves high effective-throughput of time-lapse microscopy experiments. Liang G, Yin H, Allard J, Ding F PloS one 36301804 PLoS One 2022 https://www.ncbi.nlm.nih.gov/pubmed/36301804
Inferring stochastic rates from heterogeneous snapshots of particle positions. Miles CE, McKinley SA, Ding F, Lehoucq RB ArXiv 37986720 ArXiv 2023 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/37986720
XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells. Dror I, Chitiashvili T, Tan SYX, Cano CT, Sahakyan A, Markaki Y, Chronis C, Collier AJ, Deng W, Liang G, Sun Y, Afasizheva A, Miller J, Xiao W, Black DL, Ding F, Plath K Cell 38181737 Cell 2024 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/38181737
FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1. Cho S, Chun Y, He L, Ramirez CB, Ganesh KS, Jeong K, Song J, Cheong JG, Li Z, Choi J, Kim J, Koundouros N, Ding F, Dephoure N, Jang C, Blenis J, Lee G Molecular cell 37595559 Mol Cell 2023 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/37595559
Inferring Stochastic Rates from Heterogeneous Snapshots of Particle Positions. Miles CE, McKinley SA, Ding F, Lehoucq RB Bulletin of mathematical biology 38740619 Bull Math Biol 2024 May 13 https://www.ncbi.nlm.nih.gov/pubmed/38740619
Displacement and dissociation of oligonucleotides during DNA hairpin closure under strain. Ding F, Cocco S, Raj S, Manosas M, Nguyen TTT, Spiering MM, Bensimon D, Allemand JF, Croquette V Nucleic acids research 36478056 Nucleic Acids Res 2022 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/36478056
Wafer-Scale Fabrication of Uniform, Micrometer-Sized, Triangular Membranes on Sapphire for High-Speed Protein Sensing in a Nanopore. Xia P, Rahman Laskar MA, Wang C ACS applied materials & interfaces 36598264 ACS Appl Mater Interfaces 2023 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/36598264
Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket. Shi H, Ditter IA, Oken AC, Mansoor SE Science advances 39823330 Sci Adv 2025 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/39823330
High-affinity agonism at the P2X(7) receptor is mediated by three residues outside the orthosteric pocket. Oken AC, Lisi NE, Krishnamurthy I, McCarthy AE, Godsey MH, Glasfeld A, Mansoor SE Nature communications 39107314 Nat Commun 2024 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/39107314
P2X(7) receptors exhibit at least three modes of allosteric antagonism. Oken AC, Ditter IA, Lisi NE, Krishnamurthy I, Godsey MH, Mansoor SE Science advances 39365862 Sci Adv 2024 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/39365862
Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding. Oken AC, Lisi NE, Ditter IA, Shi H, Nechiporuk NA, Mansoor SE Nature communications 39353889 Nat Commun 2024 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/39353889
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Dimerization of the deaminase domain and locking interactions with Cas9 boost base editing efficiency in ABE8e. Arantes PR, Chen X, Sinha S, Saha A, Patel AC, Sample M, Nierzwicki Ł, Lapinaite A, Palermo G Nucleic acids research 39569582 Nucleic Acids Res 2024 Dec 11 https://www.ncbi.nlm.nih.gov/pubmed/39569582
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Mitochondrially-associated actin waves maintain organelle homeostasis and equitable inheritance. Coscia SM, Moore AS, Wong YC, Holzbaur ELF Current opinion in cell biology 38692079 Curr Opin Cell Biol 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38692079
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Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response. Chen Y, Quan S, Patil V, Kunjamma RB, Tokars HM, Leisten ED, Joy G, Wills S, Chan JR, Wong YC, Popko B Glia 37203250 Glia 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37203250
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Social evolution of shared biofilm matrix components. Tai JB, Mukherjee S, Nero T, Olson R, Tithof J, Nadell CD, Yan J Proceedings of the National Academy of Sciences of the United States of America 35771939 Proc Natl Acad Sci U S A 2022 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/35771939
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An Atlas of Variant Effects to understand the genome at nucleotide resolution. Fowler DM, Adams DJ, Gloyn AL, Hahn WC, Marks DS, Muffley LA, Neal JT, Roth FP, Rubin AF, Starita LM, Hurles ME Genome biology 37394429 Genome Biol 2023 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/37394429
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Machine learning-optimized targeted detection of alternative splicing. Yang K, Islas N, Jewell S, Jha A, Radens CM, Pleiss JA, Lynch KW, Barash Y, Choi PS bioRxiv : the preprint server for biology 39386495 bioRxiv 2024 Sep 24 https://www.ncbi.nlm.nih.gov/pubmed/39386495
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Machine learning-optimized targeted detection of alternative splicing. Yang K, Islas N, Jewell S, Wu D, Jha A, Radens CM, Pleiss JA, Lynch KW, Barash Y, Choi PS Nucleic acids research 39727154 Nucleic Acids Res 2025 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/39727154
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cGLRs are a diverse family of pattern recognition receptors in animal innate immunity. Li Y, Slavik KM, Morehouse BR, de Oliveira Mann CC, Mears K, Liu J, Kashin D, Schwede F, Kranzusch PJ bioRxiv : the preprint server for biology 36865129 bioRxiv 2023 Feb 22 https://www.ncbi.nlm.nih.gov/pubmed/36865129
Structural basis of human TREX1 DNA degradation and autoimmune disease. Zhou W, Richmond-Buccola D, Wang Q, Kranzusch PJ Nature communications 35879334 Nat Commun 2022 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/35879334
Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity. Hobbs SJ, Wein T, Lu A, Morehouse BR, Schnabel J, Leavitt A, Yirmiya E, Sorek R, Kranzusch PJ Nature 35395152 Nature 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35395152
Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS. Scott TM, Arnold LM, Powers JA, McCann DA, Rowe AB, Christensen DE, Pereira MJ, Zhou W, Torrez RM, Iwasa JH, Kranzusch PJ, Sundquist WI, Johnson JS bioRxiv : the preprint server for biology 38712059 bioRxiv 2024 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/38712059
Convergent mutations in phage virion assembly proteins enable evasion of Type I CBASS immunity. Richmond-Buccola D, Hobbs SJ, Garcia JM, Toyoda H, Gao J, Shao S, Lee ASY, Kranzusch PJ bioRxiv : the preprint server for biology 37292831 bioRxiv 2023 May 22 https://www.ncbi.nlm.nih.gov/pubmed/37292831
The virus-induced cyclic dinucleotide 2'3'-c-di-GMP mediates STING-dependent antiviral immunity in Drosophila. Cai H, Li L, Slavik KM, Huang J, Yin T, Ai X, Hédelin L, Haas G, Xiang Z, Yang Y, Li X, Chen Y, Wei Z, Deng H, Chen D, Jiao R, Martins N, Meignin C, Kranzusch PJ, Imler JL Immunity 37659413 Immunity 2023 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/37659413
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CARD-like domains mediate anti-phage defense in bacterial gasdermin systems. Wein T, Johnson AG, Millman A, Lange K, Yirmiya E, Hadary R, Garb J, Steinruecke F, Hill AB, Kranzusch PJ, Sorek R bioRxiv : the preprint server for biology 37398489 bioRxiv 2023 May 29 https://www.ncbi.nlm.nih.gov/pubmed/37398489
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A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion. Richmond-Buccola D, Hobbs SJ, Garcia JM, Toyoda H, Gao J, Shao S, Lee ASY, Kranzusch PJ Cell host & microbe 38917809 Cell Host Microbe 2024 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/38917809
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Diversity of ribosomes at the level of rRNA variation associated with human health and disease. Rothschild D, Susanto TT, Sui X, Spence JP, Rangan R, Genuth NR, Sinnott-Armstrong N, Wang X, Pritchard JK, Barna M bioRxiv : the preprint server for biology 36778251 bioRxiv 2024 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/36778251
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Chemical and topological design of multicapped mRNA and capped circular RNA to augment translation. Chen H, Liu D, Aditham A, Guo J, Huang J, Kostas F, Maher K, Friedrich MJ, Xavier RJ, Zhang F, Wang X Nature biotechnology 39313647 Nat Biotechnol 2024 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/39313647
Live cell single-molecule imaging to study DNA repair in human cells. Heyza JR, Mikhova M, Schmidt JC DNA repair 37467632 DNA Repair (Amst) 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37467632
Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates. Broadbent DG, McEwan CM, Jayatunge D, Kaminsky EG, Tsang TM, Poole DM, Naylor BC, Price JC, Schmidt JC, Andersen JL Molecular biology of the cell 39718773 Mol Biol Cell 2025 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/39718773
TRF1 and TRF2 form distinct shelterin subcomplexes at telomeres. Janovič T, Perez GI, Schmidt JC bioRxiv : the preprint server for biology 39763972 bioRxiv 2024 Dec 23 https://www.ncbi.nlm.nih.gov/pubmed/39763972
The PST repeat region of MDC1 is a tunable multivalent chromatin tethering domain. Heyza JR, Mikhova M, Perez GI, Broadbent DG, Schmidt JC bioRxiv : the preprint server for biology 39868091 bioRxiv 2025 Jan 13 https://www.ncbi.nlm.nih.gov/pubmed/39868091
Systematic analysis of the molecular and biophysical properties of key DNA damage response factors. Heyza JR, Mikhova M, Bahl A, Broadbent DG, Schmidt JC eLife 37341699 Elife 2023 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/37341699
The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy. Broadbent DG, McEwan CM, Tsang TM, Poole DM, Naylor BC, Price JC, Schmidt JC, Andersen JL bioRxiv : the preprint server for biology 38077022 bioRxiv 2023 Nov 29 https://www.ncbi.nlm.nih.gov/pubmed/38077022
RHINO restricts MMEJ activity to mitosis. Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A bioRxiv : the preprint server for biology 36993461 bioRxiv 2023 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/36993461
PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress. Mashayekhi F, Ganje C, Caron MC, Heyza JR, Gao Y, Zeinali E, Fanta M, Li L, Ali J, Mersaoui SY, Schmidt JC, Godbout R, Masson JY, Weinfeld M, Ismail IH Cell reports 39671289 Cell Rep 2024 Dec 24 https://www.ncbi.nlm.nih.gov/pubmed/39671289
Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation. Broadbent DG, Barnaba C, Perez GI, Schmidt JC The Journal of cell biology 37115157 J Cell Biol 2023 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/37115157
Tracking the transition from an ATG9A vesicle to an autophagosome. Broadbent D, Barnaba C, Schmidt JC Autophagy 37405380 Autophagy 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/37405380
RHINO directs MMEJ to repair DNA breaks in mitosis. Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A Science (New York, N.Y.) 37440612 Science 2023 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/37440612
Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells. Mikhova M, Goff NJ, Janovič T, Heyza JR, Meek K, Schmidt JC Nature communications 39578493 Nat Commun 2024 Nov 23 https://www.ncbi.nlm.nih.gov/pubmed/39578493
AMPK regulates phagophore-to-autophagosome maturation. Barnaba C, Broadbent DG, Kaminsky EG, Perez GI, Schmidt JC The Journal of cell biology 38775785 J Cell Biol 2024 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/38775785
AMPK Regulates Phagophore-to-Autophagosome Maturation. Barnaba C, Broadbent DG, Perez GI, Schmidt JC bioRxiv : the preprint server for biology 37808644 bioRxiv 2023 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/37808644
Single-molecule imaging reveals the kinetics of non-homologous end-joining in living cells. Mikhova M, Goff NJ, Janovič T, Heyza JR, Meek K, Schmidt JC bioRxiv : the preprint server for biology 38826211 bioRxiv 2024 May 25 https://www.ncbi.nlm.nih.gov/pubmed/38826211
Native SAD phasing at room temperature. Greisman JB, Dalton KM, Sheehan CJ, Klureza MA, Kurinov I, Hekstra DR Acta crystallographica. Section D, Structural biology 35916223 Acta Crystallogr D Struct Biol 2022 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/35916223
Correcting systematic errors in diffraction data with modern scaling algorithms. Aldama LA, Dalton KM, Hekstra DR Acta crystallographica. Section D, Structural biology 37584427 Acta Crystallogr D Struct Biol 2023 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/37584427
Insights into VDAC Gating: Room-Temperature X-ray Crystal Structure of mVDAC-1. Gonzalez-DeWhitt KR, Ermolova N, Wang HK, Hekstra DR, Althoff T, Abramson J Biomolecules 39456136 Biomolecules 2024 Sep 24 https://www.ncbi.nlm.nih.gov/pubmed/39456136
Resolving DJ-1 Glyoxalase Catalysis Using Mix-and-Inject Serial Crystallography at a Synchrotron. Zielinski KA, Dolamore C, Dalton KM, Smith N, Termini J, Henning R, Srajer V, Hekstra DR, Pollack L, Wilson MA bioRxiv : the preprint server for biology 39071394 bioRxiv 2024 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/39071394
MatchMaps: non-isomorphous difference maps for X-ray crystallography. Brookner DE, Hekstra DR Journal of applied crystallography 38846758 J Appl Crystallogr 2024 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/38846758
Scaling and Merging Time-Resolved Laue Data with Variational Inference. Zielinski KA, Dolamore C, Wang HK, Henning RW, Wilson MA, Pollack L, Srajer V, Hekstra DR, Dalton KM bioRxiv : the preprint server for biology 39131362 bioRxiv 2024 Jul 31 https://www.ncbi.nlm.nih.gov/pubmed/39131362
Mapping protein conformational landscapes from crystallographic drug fragment screens. Saeed AA, Klureza MA, Hekstra DR bioRxiv : the preprint server for biology 39131376 bioRxiv 2024 Jul 30 https://www.ncbi.nlm.nih.gov/pubmed/39131376
Scaling and merging time-resolved pink-beam diffraction with variational inference. Zielinski KA, Dolamore C, Wang HK, Henning RW, Wilson MA, Pollack L, Srajer V, Hekstra DR, Dalton KM Structural dynamics (Melville, N.Y.) 39629168 Struct Dyn 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/39629168
Mapping Protein Conformational Landscapes from Crystallographic Drug Fragment Screens. Saeed AA, Klureza MA, Hekstra DR Journal of chemical information and modeling 39530154 J Chem Inf Model 2024 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/39530154
AlphaFold as a Prior: Experimental Structure Determination Conditioned on a Pretrained Neural Network. Fadini A, Li M, McCoy AJ, Terwilliger TC, Read RJ, Hekstra D, AlQuraishi M bioRxiv : the preprint server for biology 40027838 bioRxiv 2025 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/40027838
SFCalculator: connecting deep generative models and crystallography. Li M, Dalton K, Hekstra D bioRxiv : the preprint server for biology 39868231 bioRxiv 2025 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/39868231
Laue-DIALS: open-source software for polychromatic X-ray diffraction data. Hewitt RA, Dalton KM, Mendez D, Wang HK, Klureza MA, Brookner DE, Greisman JB, McDonagh D, Šrajer V, Sauter NK, Brewster AS, Hekstra DR bioRxiv : the preprint server for biology 39091818 bioRxiv 2024 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/39091818
Sensitive Detection of Structural Differences using a Statistical Framework for Comparative Crystallography. Hekstra DR, Wang HK, Klureza MA, Greisman JB, Dalton KM bioRxiv : the preprint server for biology 39091831 bioRxiv 2024 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/39091831
Resolving conformational changes that mediate a two-step catalytic mechanism in a model enzyme. Greisman JB, Dalton KM, Brookner DE, Klureza MA, Sheehan CJ, Kim IS, Henning RW, Russi S, Hekstra DR bioRxiv : the preprint server for biology 37398233 bioRxiv 2023 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/37398233
A unifying Bayesian framework for merging X-ray diffraction data. Dalton KM, Greisman JB, Hekstra DR Nature communications 36522310 Nat Commun 2022 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/36522310
MatchMaps: Non-isomorphous difference maps for X-ray crystallography. Brookner DE, Hekstra DR bioRxiv : the preprint server for biology 37732267 bioRxiv 2024 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/37732267
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Greisman JB, Dalton KM, Brookner DE, Klureza MA, Sheehan CJ, Kim IS, Henning RW, Russi S, Hekstra DR Proceedings of the National Academy of Sciences of the United States of America 38386706 Proc Natl Acad Sci U S A 2024 Feb 27 https://www.ncbi.nlm.nih.gov/pubmed/38386706
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Emerging Time-Resolved X-Ray Diffraction Approaches for Protein Dynamics. Hekstra DR Annual review of biophysics 37159292 Annu Rev Biophys 2023 May 9 https://www.ncbi.nlm.nih.gov/pubmed/37159292
Direct visualization of electric-field-stimulated ion conduction in a potassium channel. Lee B, White KI, Socolich M, Klureza MA, Henning R, Srajer V, Ranganathan R, Hekstra DR Cell 39793560 Cell 2025 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/39793560
Noncoding translation mitigation. Kesner JS, Chen Z, Shi P, Aparicio AO, Murphy MR, Guo Y, Trehan A, Lipponen JE, Recinos Y, Myeku N, Wu X Nature 37046090 Nature 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37046090
Finding functional microproteins. Azam S, Yang F, Wu X Trends in genetics : TIG 39753408 Trends Genet 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39753408
Collateral activity of the CRISPR/RfxCas13d system in human cells. Shi P, Murphy MR, Aparicio AO, Kesner JS, Fang Z, Chen Z, Trehan A, Guo Y, Wu X Communications biology 36977923 Commun Biol 2023 Mar 28 https://www.ncbi.nlm.nih.gov/pubmed/36977923
Programmable RNA targeting with CRISPR-Cas13. Shi P, Wu X RNA biology 38764173 RNA Biol 2024 Jan https://www.ncbi.nlm.nih.gov/pubmed/38764173
Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments. Goel VY, Huseyin MK, Hansen AS Nature genetics 37157000 Nat Genet 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/37157000
Enhancer selectivity in space and time: from enhancer-promoter interactions to promoter activation. Yang JH, Hansen AS Nature reviews. Molecular cell biology 38413840 Nat Rev Mol Cell Biol 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38413840
Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation. Kim KL, Rahme GJ, Goel VY, El Farran CA, Hansen AS, Bernstein BE Molecular cell 38452764 Mol Cell 2024 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/38452764
Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging. Mahadevan J, Jha A, Rudolph J, Bowerman S, Narducci D, Hansen AS, Luger K iScience 36594010 iScience 2023 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/36594010
LDB1 establishes multi-enhancer networks to regulate gene expression. Aboreden NG, Lam JC, Goel VY, Wang S, Wang X, Midla SC, Quijano A, Keller CA, Giardine BM, Hardison RC, Zhang H, Hansen AS, Blobel GA bioRxiv : the preprint server for biology 39229045 bioRxiv 2024 Aug 24 https://www.ncbi.nlm.nih.gov/pubmed/39229045
Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project. Dekker J, Alber F, Aufmkolk S, Beliveau BJ, Bruneau BG, Belmont AS, Bintu L, Boettiger A, Calandrelli R, Disteche CM, Gilbert DM, Gregor T, Hansen AS, Huang B, Huangfu D, Kalhor R, Leslie CS, Li W, Li Y, Ma J, Noble WS, Park PJ, Phillips-Cremins JE, Pollard KS, Rafelski SM, Ren B, Ruan Y, Shav-Tal Y, Shen Y, Shendure J, Shu X, Strambio-De-Castillia C, Vertii A, Zhang H, Zhong S Molecular cell 37419111 Mol Cell 2023 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/37419111
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Integrative PTEN Enhancer Discovery Reveals a New Model of Enhancer Organization. Cerda-Smith CG, Hutchinson HM, Liu A, Goel VY, Sept C, Kim H, Casaní-Galdón S, Burkman KG, Bassil CF, Hansen AS, Aryee MJ, Johnstone SE, Eyler CE, Wood KC bioRxiv : the preprint server for biology 37786671 bioRxiv 2023 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/37786671
An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing. Waterbury AL, Kwok HS, Lee C, Narducci DN, Freedy AM, Su C, Raval S, Reiter AH, Hawkins W, Lee K, Li J, Hoenig SM, Vinyard ME, Cole PA, Hansen AS, Carr SA, Papanastasiou M, Liau BB Molecular cell 38870936 Mol Cell 2024 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/38870936
Tracking and interpreting long-range chromatin interactions with super-resolution live-cell imaging. Brandão HB, Gabriele M, Hansen AS Current opinion in cell biology 33310227 Curr Opin Cell Biol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33310227
Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging. Gabriele M, Brandão HB, Grosse-Holz S, Jha A, Dailey GM, Cattoglio C, Hsieh TS, Mirny L, Zechner C, Hansen AS Science (New York, N.Y.) 35420890 Science 2022 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/35420890
Reeling it in: how DNA topology drives loop extrusion by condensin. Narducci DN, Hansen AS Nature structural & molecular biology 35835869 Nat Struct Mol Biol 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35835869
Genome-wide absolute quantification of chromatin looping. Jusuf JM, Grosse-Holz S, Gabriele M, Mach P, Flyamer IM, Zechner C, Giorgetti L, Mirny LA, Hansen AS bioRxiv : the preprint server for biology 39935886 bioRxiv 2025 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/39935886
Enhancer-promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1. Hsieh TS, Cattoglio C, Slobodyanyuk E, Hansen AS, Darzacq X, Tjian R Nature genetics 36471071 Nat Genet 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36471071
A Protocol for Studying Transcription Factor Dynamics Using Fast Single-Particle Tracking and Spot-On Model-Based Analysis. Jha A, Hansen AS Methods in molecular biology (Clifton, N.J.) 35103967 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35103967
Promoters adopt distinct dynamic manifestations depending on transcription factor context. Hansen AS, Zechner C Molecular systems biology 33595925 Mol Syst Biol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33595925
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Beyond circadian rhythms: emerging roles of ultradian rhythms in control of liver functions. Asher G, Zhu B Hepatology (Baltimore, Md.) 35591797 Hepatology 2023 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/35591797
LEF1 isoforms regulate cellular senescence and aging. Jia M, Sayed K, Kapetanaki MG, Dion W, Rosas L, Irfan S, Valenzi E, Mora AL, Lafyatis RA, Rojas M, Zhu B, Benos PV bioRxiv : the preprint server for biology 37502913 bioRxiv 2023 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/37502913
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Logic of the Temporal Compartmentalization of the Hepatic Metabolic Cycle. Zhu B Physiology (Bethesda, Md.) 35658626 Physiology (Bethesda) 2022 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/35658626
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Twelve-hour rhythms in transcript expression within the human dorsolateral prefrontal cortex are altered in schizophrenia. Scott MR, Zong W, Ketchesin KD, Seney ML, Tseng GC, Zhu B, McClung CA PLoS biology 36693045 PLoS Biol 2023 Jan https://www.ncbi.nlm.nih.gov/pubmed/36693045
Temporal gene expression patterns in the coral Euphyllia paradivisa reveal the complexity of biological clocks in the cnidarian-algal symbiosis. Rinsky M, Weizman E, Ben-Asher HW, Eyal G, Zhu B, Levy O Science advances 36112690 Sci Adv 2022 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/36112690
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Previously hidden intraspecies dynamics underlie the apparent stability of two important skin microbiome species. Baker JS, Qu E, Mancuso CP, Tripp AD, Conwill A, Lieberman TD bioRxiv : the preprint server for biology 38260404 bioRxiv 2025 Jan 31 https://www.ncbi.nlm.nih.gov/pubmed/38260404
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Detecting bacterial adaptation within individual microbiomes. Lieberman TD Philosophical transactions of the Royal Society of London. Series B, Biological sciences 35989602 Philos Trans R Soc Lond B Biol Sci 2022 Oct 10 https://www.ncbi.nlm.nih.gov/pubmed/35989602
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Circularized fluorescent nanodiscs for probing protein-lipid interactions. Ren Q, Zhang S, Bao H Communications biology 35618817 Commun Biol 2022 May 26 https://www.ncbi.nlm.nih.gov/pubmed/35618817
Targeting Recycling Endosomes to Potentiate mRNA Lipid Nanoparticles. Shin J, Douglas CJ, Zhang S, Seath CP, Bao H Nano letters 38640421 Nano Lett 2024 May 1 https://www.ncbi.nlm.nih.gov/pubmed/38640421
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Developing Nanodisc-ID for label-free characterizations of membrane proteins. Bao H Communications biology 33931748 Commun Biol 2021 Apr 30 https://www.ncbi.nlm.nih.gov/pubmed/33931748
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Designer Nanodiscs to Probe and Reprogram Membrane Biology in Synapses. Dallo S, Shin J, Zhang S, Ren Q, Bao H Journal of molecular biology 35872069 J Mol Biol 2023 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/35872069
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Bringing Vibrational Imaging to Chemical Biology with Molecular Probes. Du J, Wang H, Wei L ACS chemical biology 35772040 ACS Chem Biol 2022 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/35772040
Seeing is Believing: Developing Multimodal Metabolic Insights at the Molecular Level. Chadha RS, Guerrero JA, Wei L, Sanchez LM ACS central science 38680555 ACS Cent Sci 2024 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/38680555
Toward the Next Frontiers of Vibrational Bioimaging. Wang H, Lee D, Wei L Chemical & biomedical imaging 37122829 Chem Biomed Imaging 2023 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/37122829
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Bond-selective fluorescence imaging with single-molecule sensitivity. Wang H, Lee D, Cao Y, Bi X, Du J, Miao K, Wei L Nature photonics 38162388 Nat Photonics 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/38162388
Nitrile Vibrational Lifetimes as Probes of Local Electric Fields. Kocheril PA, Wang H, Lee D, Naji N, Wei L The journal of physical chemistry letters 38722706 J Phys Chem Lett 2024 May 16 https://www.ncbi.nlm.nih.gov/pubmed/38722706
Room-Temperature Single-Molecule Infrared Imaging and Spectroscopy through Bond-Selective Fluorescence. Wang H, Kocheril PA, Yang Z, Lee D, Naji N, Du J, Lin LE, Wei L Angewandte Chemie (International ed. in English) 39312677 Angew Chem Int Ed Engl 2024 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/39312677
Toward photoswitchable electronic pre-resonance stimulated Raman probes. Lee D, Qian C, Wang H, Li L, Miao K, Du J, Shcherbakova DM, Verkhusha VV, Wang LV, Wei L The Journal of chemical physics 33832245 J Chem Phys 2021 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/33832245
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Reentrant DNA shells tune polyphosphate condensate size. Chawla R, Tom JKA, Boyd T, Grotjahn DA, Park D, Deniz AA, Racki LR bioRxiv : the preprint server for biology 37745474 bioRxiv 2023 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/37745474
Polyphosphate: The "Dark Matter" of Bacterial Chromatin Structure. Racki LR, Freddolino L Molecular microbiology 39967274 Mol Microbiol 2025 Mar https://www.ncbi.nlm.nih.gov/pubmed/39967274
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A High-Throughput Colocalization Pipeline for Quantification of Mitochondrial Targeting across Different Protein Types. Lear SK, Nunez JA, Shipman SL ACS synthetic biology 37506292 ACS Synth Biol 2023 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/37506292
An experimental census of retrons for DNA production and genome editing. Khan AG, Rojas-Montero M, González-Delgado A, Lopez SC, Fang RF, Shipman SL bioRxiv : the preprint server for biology 38328236 bioRxiv 2024 Jan 26 https://www.ncbi.nlm.nih.gov/pubmed/38328236
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One-step data storage in cellular DNA. Bhattarai-Kline S, Lear SK, Shipman SL Nature chemical biology 33500580 Nat Chem Biol 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33500580
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Retron reverse transcriptase termination and phage defense are dependent on host RNase H1. Palka C, Fishman CB, Bhattarai-Kline S, Myers SA, Shipman SL Nucleic acids research 35293583 Nucleic Acids Res 2022 Apr 8 https://www.ncbi.nlm.nih.gov/pubmed/35293583
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Continuous Multiplexed Phage Genome Editing Using Recombitrons. Fishman CB, Crawford KD, Bhattarai-Kline S, Zhang K, González-Delgado A, Shipman SL bioRxiv : the preprint server for biology 36993281 bioRxiv 2023 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/36993281
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OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human. Huang X, Park KM, Gontarz P, Zhang B, Pan J, McKenzie Z, Fischer LA, Dong C, Dietmann S, Xing X, Shliaha PV, Yang J, Li D, Ding J, Lungjangwa T, Mitalipova M, Khan SA, Imsoonthornruksa S, Jensen N, Wang T, Kadoch C, Jaenisch R, Wang J, Theunissen TW Nature communications 34446700 Nat Commun 2021 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/34446700
A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. Dong C, Fu S, Karvas RM, Chew B, Fischer LA, Xing X, Harrison JK, Popli P, Kommagani R, Wang T, Zhang B, Theunissen TW Nature communications 35538076 Nat Commun 2022 May 10 https://www.ncbi.nlm.nih.gov/pubmed/35538076
Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening. Khan SA, Park KM, Fischer LA, Dong C, Lungjangwa T, Jimenez M, Casalena D, Chew B, Dietmann S, Auld DS, Jaenisch R, Theunissen TW Cell reports 34133938 Cell Rep 2021 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/34133938
iPSC-based modeling of preeclampsia identifies epigenetic defects in extravillous trophoblast differentiation. Morey R, Bui T, Cheung VC, Dong C, Zemke JE, Requena D, Arora H, Jackson MG, Pizzo D, Theunissen TW, Horii M iScience 38623329 iScience 2024 Apr 19 https://www.ncbi.nlm.nih.gov/pubmed/38623329
Generation of 3D Trophoblast Organoids from Human Naïve Pluripotent Stem Cells. Karvas RM, Theunissen TW Methods in molecular biology (Clifton, N.J.) 37402094 Methods Mol Biol 2024 https://www.ncbi.nlm.nih.gov/pubmed/37402094
Modular control of l-tryptophan isotopic substitution via an efficient biosynthetic cascade. Thompson CM, McDonald AD, Yang H, Cavagnero S, Buller AR Organic & biomolecular chemistry 32452506 Org Biomol Chem 2020 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/32452506
Site-Selective Deuteration of Amino Acids through Dual-Protein Catalysis. Doyon TJ, Buller AR Journal of the American Chemical Society 35416652 J Am Chem Soc 2022 Apr 27 https://www.ncbi.nlm.nih.gov/pubmed/35416652
Biocatalytic synthesis of non-standard amino acids by a decarboxylative aldol reaction. Ellis JM, Campbell ME, Kumar P, Geunes EP, Bingman CA, Buller AR Nature catalysis 35935533 Nat Catal 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/35935533
Multiplexed Assessment of Promiscuous Non-Canonical Amino Acid Synthase Activity in a Pyridoxal Phosphate-Dependent Protein Family. Zmich A, Perkins LJ, Bingman C, Acheson JF, Buller AR ACS catalysis 37720819 ACS Catal 2023 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/37720819
Occupational modulation in the (3+1)-dimensional incommensurate structure of (2S,3S)-2-amino-3-hydroxy-3-methyl-4-phenoxybutanoic acid dihydrate. Sanders KM, Bruffy SK, Buller AR, Petříček V, Guzei IA Acta crystallographica. Section C, Structural chemistry 39115533 Acta Crystallogr C Struct Chem 2024 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/39115533
Substrate-Multiplexed Assessment of Aromatic Prenyltransferase Activity. Higgins PM, Wehrli NG, Buller AR Chembiochem : a European journal of chemical biology 39317170 Chembiochem 2025 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/39317170
l-Threonine Transaldolase Activity Is Enabled by a Persistent Catalytic Intermediate. Kumar P, Meza A, Ellis JM, Carlson GA, Bingman CA, Buller AR ACS chemical biology 33337128 ACS Chem Biol 2021 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/33337128
Engineered Biocatalytic Synthesis of β-N-Substituted-α-Amino Acids. Villalona J, Higgins PM, Buller AR Angewandte Chemie (International ed. in English) 37625129 Angew Chem Int Ed Engl 2023 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/37625129
Scalable and Selective β-Hydroxy-α-Amino Acid Synthesis Catalyzed by Promiscuous l-Threonine Transaldolase ObiH. Doyon TJ, Kumar P, Thein S, Kim M, Stitgen A, Grieger AM, Madigan C, Willoughby PH, Buller AR Chembiochem : a European journal of chemical biology 34699683 Chembiochem 2022 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/34699683
Asymmetric Alkylation of Ketones Catalyzed by Engineered TrpB. Watkins-Dulaney EJ, Dunham NP, Straathof S, Turi S, Arnold FH, Buller AR Angewandte Chemie (International ed. in English) 34269506 Angew Chem Int Ed Engl 2021 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/34269506
Efficient chemoenzymatic synthesis of α-aryl aldehydes as intermediates in C-C bond forming biocatalytic cascades. Meza A, Campbell ME, Zmich A, Thein SA, Grieger AM, McGill MJ, Willoughby PH, Buller AR ACS catalysis 36420479 ACS Catal 2022 Sep 2 https://www.ncbi.nlm.nih.gov/pubmed/36420479
Elucidation of the stereochemical mechanism of cystathionine γ-lyase reveals how substrate specificity constrains catalysis. Zmich A, Perkins LJ, Bingman C, Buller AR ACS catalysis 39391268 ACS Catal 2024 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/39391268
Biocatalytic asymmetric aldol addition into unactivated ketones. Bruffy SK, Meza A, Soler J, Doyon TJ, Young SH, Lim J, Huseth KG, Willoughby PH, Garcia-Borràs M, Buller AR Nature chemistry 39333392 Nat Chem 2024 Dec https://www.ncbi.nlm.nih.gov/pubmed/39333392
Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis. McDonald AD, Higgins PM, Buller AR Nature communications 36068220 Nat Commun 2022 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/36068220
Investigation of β-Substitution Activity of O-Acetylserine Sulfhydrolase from Citrullus vulgaris. Smith JL, Harrison IM, Bingman CA, Buller AR Chembiochem : a European journal of chemical biology 35476889 Chembiochem 2022 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/35476889
Engineering Enzyme Substrate Scope Complementarity for Promiscuous Cascade Synthesis of 1,2-Amino Alcohols. McDonald AD, Bruffy SK, Kasat AT, Buller AR Angewandte Chemie (International ed. in English) 36136093 Angew Chem Int Ed Engl 2022 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/36136093
Efficient and flexible tagging of endogenous genes by homology-independent intron targeting. Serebrenik YV, Sansbury SE, Kumar SS, Henao-Mejia J, Shalem O Genome research 31239279 Genome Res 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31239279
CRISPR associated enzymes are mislocalized to the cytoplasm in iPSC-derived neurons resulting in KRAB-specific degradation. Cajka G, Liu M, Shalem O bioRxiv : the preprint server for biology 39464063 bioRxiv 2024 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/39464063
Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics. Serebrenik YV, Mani D, Maujean T, Burslem GM, Shalem O Research square 37790450 Res Sq 2023 Sep 13 https://www.ncbi.nlm.nih.gov/pubmed/37790450
CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. Sweeney KM, Chantarawong S, Barbieri EM, Cajka G, Liu M, Spruce L, Fazelinia H, Portz B, Copley K, Lapidot T, Duhamel L, Greenwald P, Saida N, Shalgi R, Shorter J, Shalem O PLoS genetics 38315730 PLoS Genet 2024 Feb https://www.ncbi.nlm.nih.gov/pubmed/38315730
Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses. Sansbury SE, Serebrenik YV, Lapidot T, Burslem GM, Shalem O bioRxiv : the preprint server for biology 37503003 bioRxiv 2023 Jul 14 https://www.ncbi.nlm.nih.gov/pubmed/37503003
Pooled endogenous protein tagging and recruitment for systematic profiling of protein function. Serebrenik YV, Mani D, Maujean T, Burslem GM, Shalem O Cell genomics 39255790 Cell Genom 2024 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/39255790
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins. Viera Ortiz AP, Cajka G, Olatunji OA, Mikytuck B, Shalem O, Lee EB Brain : a journal of neurology 36516294 Brain 2023 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/36516294
Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin function and life span. Garcia G, Bar-Ziv R, Averbukh M, Dasgupta N, Dutta N, Zhang H, Fan W, Moaddeli D, Tsui CK, Castro Torres T, Alcala A, Moehle EA, Hoang S, Shalem O, Adams PD, Thorwald MA, Higuchi-Sanabria R Aging cell 36404134 Aging Cell 2023 Jan https://www.ncbi.nlm.nih.gov/pubmed/36404134
High-throughput optimized prime editing mediated endogenous protein tagging for pooled imaging of protein localization. Sanchez HM, Lapidot T, Shalem O bioRxiv : the preprint server for biology 39345511 bioRxiv 2024 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/39345511
Intracellular Protein Editing to Enable Incorporation of Non-Canonical Residues into Endogenous Proteins. Beyer JN, Serebrenik YV, Toy K, Najar MA, Raniszewski NR, Shalem O, Burslem GM bioRxiv : the preprint server for biology 39026884 bioRxiv 2024 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/39026884
CRISPR screen for rAAV production implicates genes associated with infection. O'Driscoll EE, Arora S, Lang JF, Davidson BL, Shalem O bioRxiv : the preprint server for biology 39345423 bioRxiv 2024 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/39345423
ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins. McKenna MJ, Adams BM, Chu V, Paulo JA, Shao S Molecular cell 36283413 Mol Cell 2022 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/36283413
Detecting and Rescuing Stalled Ribosomes. Yip MCJ, Shao S Trends in biochemical sciences 33966939 Trends Biochem Sci 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/33966939
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase. McKenna MJ, Sim SI, Ordureau A, Wei L, Harper JW, Shao S, Park E Science (New York, N.Y.) 32973005 Science 2020 Sep 25 https://www.ncbi.nlm.nih.gov/pubmed/32973005
Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. Koga Y, Hoang EM, Park Y, Keszei AFA, Murray J, Shao S, Liau BB Journal of the American Chemical Society 34403584 J Am Chem Soc 2021 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/34403584
Mechanism of ASF1 Inhibition by CDAN1. Sedor SF, Shao S bioRxiv : the preprint server for biology 39149339 bioRxiv 2024 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/39149339
Mechanism of ASF1 engagement by CDAN1. Sedor SF, Shao S Nature communications 40091041 Nat Commun 2025 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/40091041
ELAC1 Repairs tRNAs Cleaved during Ribosome-Associated Quality Control. Yip MCJ, Savickas S, Gygi SP, Shao S Cell reports 32075755 Cell Rep 2020 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/32075755
Selective destabilization of polypeptides synthesized from NMD-targeted transcripts. Chu V, Feng Q, Lim Y, Shao S Molecular biology of the cell 34586879 Mol Biol Cell 2021 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/34586879
Mechanism of client selection by the protein quality-control factor UBE2O. Yip MCJ, Sedor SF, Shao S Nature structural & molecular biology 35915257 Nat Struct Mol Biol 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/35915257
The Endoplasmic Reticulum and the Fidelity of Nascent Protein Localization. McKenna MJ, Shao S Cold Spring Harbor perspectives in biology 36041782 Cold Spring Harb Perspect Biol 2023 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/36041782
Structural insights into metazoan pretargeting GET complexes. Keszei AFA, Yip MCJ, Hsieh TC, Shao S Nature structural & molecular biology 34887561 Nat Struct Mol Biol 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34887561
The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center. Coelho JPL, Yip MCJ, Oltion K, Taunton J, Shao S Nature chemical biology 38172604 Nat Chem Biol 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38172604
Cotranslational molecular condensation of cochaperones and assembly factors facilitates axonemal dynein biogenesis. Li Y, Xu W, Cheng Y, Djenoune L, Zhuang C, Cox AL, Britto CJ, Yuan S, Wang S, Sun Z Proceedings of the National Academy of Sciences of the United States of America 39541357 Proc Natl Acad Sci U S A 2024 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/39541357
Multiplexed imaging of nucleome architectures in single cells of mammalian tissue. Liu M, Lu Y, Yang B, Chen Y, Radda JSD, Hu M, Katz SG, Wang S Nature communications 32518300 Nat Commun 2020 Jun 9 https://www.ncbi.nlm.nih.gov/pubmed/32518300
TAD-like single-cell domain structures exist on both active and inactive X chromosomes and persist under epigenetic perturbations. Cheng Y, Liu M, Hu M, Wang S Genome biology 34749781 Genome Biol 2021 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/34749781
Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery. Liu M, Jin S, Agabiti SS, Jensen TB, Yang T, Radda JSD, Ruiz CF, Baldissera G, Rajaei M, Townsend JP, Muzumdar MD, Wang S bioRxiv : the preprint server for biology 37546882 bioRxiv 2024 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/37546882
Regulation of gene editing using T-DNA concatenation. Dickinson L, Yuan W, LeBlanc C, Thomson G, Wang S, Jacob Y Nature plants 37653336 Nat Plants 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37653336
Chromatin tracing and multiplexed imaging of nucleome architectures (MINA) and RNAs in single mammalian cells and tissue. Liu M, Yang B, Hu M, Radda JSD, Chen Y, Jin S, Cheng Y, Wang S Nature protocols 33903756 Nat Protoc 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33903756
Lamina-Dependent Stretching and Unconventional Chromosome Compartments in Early C. elegans Embryos. Sawh AN, Shafer MER, Su JH, Zhuang X, Wang S, Mango SE Molecular cell 32105612 Mol Cell 2020 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/32105612
Sequencing-free whole genome spatial transcriptomics at molecular resolution in intact tissue. Cheng Y, Dang S, Zhang Y, Chen Y, Yu R, Liu M, Jin S, Han A, Katz S, Wang S bioRxiv : the preprint server for biology 40161724 bioRxiv 2025 Mar 29 https://www.ncbi.nlm.nih.gov/pubmed/40161724
G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration. Boraas LC, Hu M, Martino P, Thornton L, Vejnar CE, Zhen G, Zeng L, Parker DM, Cox AL, Giraldez AJ, Su X, Mayr C, Wang S, Nicoli S Cell reports 39883578 Cell Rep 2025 Feb 25 https://www.ncbi.nlm.nih.gov/pubmed/39883578
New mechanism of chromatin compartmentalization by BRD2. Cheng Y, Wang S Trends in genetics : TIG 35811175 Trends Genet 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/35811175
Perturb-tracing enables high-content screening of multiscale 3D genome regulators. Cheng Y, Hu M, Yang B, Jensen TB, Yang T, Yu R, Ma Z, Radda JSD, Jin S, Zang C, Wang S bioRxiv : the preprint server for biology 36778402 bioRxiv 2023 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/36778402
Chromatin Tracing: Imaging 3D Genome and Nucleome. Hu M, Wang S Trends in cell biology 33191055 Trends Cell Biol 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33191055
An integrated platform for high-throughput nanoscopy. Barentine AES, Lin Y, Courvan EM, Kidd P, Liu M, Balduf L, Phan T, Rivera-Molina F, Grace MR, Marin Z, Lessard M, Rios Chen J, Wang S, Neugebauer KM, Bewersdorf J, Baddeley D Nature biotechnology 36914886 Nat Biotechnol 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/36914886
Induction of T-DNA amplification by retrotransposon-derived sequences. Dickinson L, Yuan W, LeBlanc C, Thomson G, Wang S, Jacob Y bioRxiv : the preprint server for biology 36945545 bioRxiv 2023 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/36945545
Female naïve human pluripotent stem cells carry X chromosomes with Xa-like and Xi-like folding conformations. Patterson B, Yang B, Tanaka Y, Kim KY, Cakir B, Xiang Y, Kim J, Wang S, Park IH Science advances 37540754 Sci Adv 2023 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/37540754
Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome. Wang SE, Cheng Y, Lim J, Jang MA, Forrest EN, Kim Y, Donahue M, Qiao SN, Xiong Y, Jin J, Wang S, Jiang YH Research square 39011107 Res Sq 2024 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/39011107
TransDiscovery: Discovering Biotransformation from Human Microbiota by Integrating Metagenomic and Metabolomic Data. Yan D, Cao L, Zhou M, Mohimani H Metabolites 35208194 Metabolites 2022 Jan 26 https://www.ncbi.nlm.nih.gov/pubmed/35208194
Bacillus subtilis biofilm matrix components target seed oil bodies to promote growth and anti-fungal resistance in melon. Berlanga-Clavero MV, Molina-Santiago C, Caraballo-Rodríguez AM, Petras D, Díaz-Martínez L, Pérez-García A, de Vicente A, Carrión VJ, Dorrestein PC, Romero D Nature microbiology 35668112 Nat Microbiol 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35668112
Feature-based molecular networking in the GNPS analysis environment. Nothias LF, Petras D, Schmid R, Dührkop K, Rainer J, Sarvepalli A, Protsyuk I, Ernst M, Tsugawa H, Fleischauer M, Aicheler F, Aksenov AA, Alka O, Allard PM, Barsch A, Cachet X, Caraballo-Rodriguez AM, Da Silva RR, Dang T, Garg N, Gauglitz JM, Gurevich A, Isaac G, Jarmusch AK, Kameník Z, Kang KB, Kessler N, Koester I, Korf A, Le Gouellec A, Ludwig M, Martin H C, McCall LI, McSayles J, Meyer SW, Mohimani H, Morsy M, Moyne O, Neumann S, Neuweger H, Nguyen NH, Nothias-Esposito M, Paolini J, Phelan VV, Pluskal T, Quinn RA, Rogers S, Shrestha B, Tripathi A, van der Hooft JJJ, Vargas F, Weldon KC, Witting M, Yang H, Zhang Z, Zubeil F, Kohlbacher O, Böcker S, Alexandrov T, Bandeira N, Wang M, Dorrestein PC Nature methods 32839597 Nat Methods 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32839597
An interpretable machine learning approach to identify mechanism of action of antibiotics. Mongia M, Guler M, Mohimani H Scientific reports 35725893 Sci Rep 2022 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/35725893
MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities. Cao L, Gurevich A, Alexander KL, Naman CB, Leão T, Glukhov E, Luzzatto-Knaan T, Vargas F, Quinn R, Bouslimani A, Nothias LF, Singh NK, Sanders JG, Benitez RAS, Thompson LR, Hamid MN, Morton JT, Mikheenko A, Shlemov A, Korobeynikov A, Friedberg I, Knight R, Venkateswaran K, Gerwick WH, Gerwick L, Dorrestein PC, Pevzner PA, Mohimani H Cell systems 31629686 Cell Syst 2019 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/31629686
Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery. Behsaz B, Bode E, Gurevich A, Shi YN, Grundmann F, Acharya D, Caraballo-Rodríguez AM, Bouslimani A, Panitchpakdi M, Linck A, Guan C, Oh J, Dorrestein PC, Bode HB, Pevzner PA, Mohimani H Nature communications 34050176 Nat Commun 2021 May 28 https://www.ncbi.nlm.nih.gov/pubmed/34050176
Chemical Gradients of Plant Substrates in an Atta texana Fungus Garden. Caraballo-Rodríguez AM, Puckett SP, Kyle KE, Petras D, da Silva R, Nothias LF, Ernst M, van der Hooft JJJ, Tripathi A, Wang M, Balunas MJ, Klassen JL, Dorrestein PC mSystems 34342533 mSystems 2021 Aug 31 https://www.ncbi.nlm.nih.gov/pubmed/34342533
Repository scale classification and decomposition of tandem mass spectral data. Mongia M, Mohimani H Scientific reports 33859284 Sci Rep 2021 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/33859284
HypoRiPPAtlas as an Atlas of hypothetical natural products for mass spectrometry database search. Lee YY, Guler M, Chigumba DN, Wang S, Mittal N, Miller C, Krummenacher B, Liu H, Cao L, Kannan A, Narayan K, Slocum ST, Roth BL, Gurevich A, Behsaz B, Kersten RD, Mohimani H Nature communications 37452020 Nat Commun 2023 Jul 14 https://www.ncbi.nlm.nih.gov/pubmed/37452020
microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data. Zuffa S, Schmid R, Bauermeister A, P Gomes PW, Caraballo-Rodriguez AM, El Abiead Y, Aron AT, Gentry EC, Zemlin J, Meehan MJ, Avalon NE, Cichewicz RH, Buzun E, Terrazas MC, Hsu CY, Oles R, Ayala AV, Zhao J, Chu H, Kuijpers MCM, Jackrel SL, Tugizimana F, Nephali LP, Dubery IA, Madala NE, Moreira EA, Costa-Lotufo LV, Lopes NP, Rezende-Teixeira P, Jimenez PC, Rimal B, Patterson AD, Traxler MF, Pessotti RC, Alvarado-Villalobos D, Tamayo-Castillo G, Chaverri P, Escudero-Leyva E, Quiros-Guerrero LM, Bory AJ, Joubert J, Rutz A, Wolfender JL, Allard PM, Sichert A, Pontrelli S, Pullman BS, Bandeira N, Gerwick WH, Gindro K, Massana-Codina J, Wagner BC, Forchhammer K, Petras D, Aiosa N, Garg N, Liebeke M, Bourceau P, Kang KB, Gadhavi H, de Carvalho LPS, Silva Dos Santos M, Pérez-Lorente AI, Molina-Santiago C, Romero D, Franke R, Brönstrup M, Vera Ponce de León A, Pope PB, La Rosa SL, La Barbera G, Roager HM, Laursen MF, Hammerle F, Siewert B, Peintner U, Licona-Cassani C, Rodriguez-Orduña L, Rampler E, Hildebrand F, Koellensperger G, Schoeny H, Hohenwallner K, Panzenboeck L, Gregor R, O'Neill EC, Roxborough ET, Odoi J, Bale NJ, Ding S, Sinninghe Damsté JS, Guan XL, Cui JJ, Ju KS, Silva DB, Silva FMR, da Silva GF, Koolen HHF, Grundmann C, Clement JA, Mohimani H, Broders K, McPhail KL, Ober-Singleton SE, Rath CM, McDonald D, Knight R, Wang M, Dorrestein PC Nature microbiology 38316926 Nat Microbiol 2024 Feb https://www.ncbi.nlm.nih.gov/pubmed/38316926
Discovering type I cis-AT polyketides through computational mass spectrometry and genome mining with Seq2PKS. Yan D, Zhou M, Adduri A, Zhuang Y, Guler M, Liu S, Shin H, Kovach T, Oh G, Liu X, Deng Y, Wang X, Cao L, Sherman DH, Schultz PJ, Kersten RD, Clement JA, Tripathi A, Behsaz B, Mohimani H Nature communications 38918378 Nat Commun 2024 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/38918378
A Metabolome- and Metagenome-Wide Association Network Reveals Microbial Natural Products and Microbial Biotransformation Products from the Human Microbiota. Cao L, Shcherbin E, Mohimani H mSystems 31455639 mSystems 2019 Aug 27 https://www.ncbi.nlm.nih.gov/pubmed/31455639
De Novo Peptide Sequencing Reveals Many Cyclopeptides in the Human Gut and Other Environments. Behsaz B, Mohimani H, Gurevich A, Prjibelski A, Fisher M, Vargas F, Smarr L, Dorrestein PC, Mylne JS, Pevzner PA Cell systems 31864964 Cell Syst 2020 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/31864964
Chemical interplay and complementary adaptative strategies toggle bacterial antagonism and co-existence. Molina-Santiago C, Vela-Corcía D, Petras D, Díaz-Martínez L, Pérez-Lorente AI, Sopeña-Torres S, Pearson J, Caraballo-Rodríguez AM, Dorrestein PC, de Vicente A, Romero D Cell reports 34320359 Cell Rep 2021 Jul 27 https://www.ncbi.nlm.nih.gov/pubmed/34320359
A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data. Zuffa S, Schmid R, Bauermeister A, Gomes PWP, Caraballo-Rodriguez AM, Abiead YE, Aron AT, Gentry EC, Zemlin J, Meehan MJ, Avalon NE, Cichewicz RH, Buzun E, Terrazas MC, Hsu CY, Oles R, Ayala AV, Zhao J, Chu H, Kuijpers MCM, Jackrel SL, Tugizimana F, Nephali LP, Dubery IA, Madala NE, Moreira EA, Costa-Lotufo LV, Lopes NP, Rezende-Teixeira P, Jimenez PC, Rimal B, Patterson AD, Traxler MF, de Cassia Pessotti R, Alvarado-Villalobos D, Tamayo-Castillo G, Chaverri P, Escudero-Leyva E, Quiros-Guerrero LM, Bory AJ, Joubert J, Rutz A, Wolfender JL, Allard PM, Sichert A, Pontrelli S, Pullman BS, Bandeira N, Gerwick WH, Gindro K, Massana-Codina J, Wagner BC, Forchhammer K, Petras D, Aiosa N, Garg N, Liebeke M, Bourceau P, Kang KB, Gadhavi H, de Carvalho LPS, Dos Santos MS, Pérez-Lorente AI, Molina-Santiago C, Romero D, Franke R, Brönstrup M, de León AVP, Pope PB, Rosa SL, Barbera G, Roager HM, Laursen MF, Hammerle F, Siewert B, Peintner U, Licona-Cassani C, Rodriguez-Orduña L, Rampler E, Hildebrand F, Koellensperger G, Schoeny H, Hohenwallner K, Panzenboeck L, Gregor R, O'Neill EC, Roxborough ET, Odoi J, Bale NJ, Ding S, Sinninghe Damsté JS, Guan XL, Cui JJ, Ju KS, Silva DB, Silva FMR, da Silva GF, Koolen HHF, Grundmann C, Clement JA, Mohimani H, Broders K, McPhail KL, Ober-Singleton SE, Rath CM, McDonald D, Knight R, Wang M, Dorrestein PC Research square 37577622 Res Sq 2023 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/37577622
MS2Planner: improved fragmentation spectra coverage in untargeted mass spectrometry by iterative optimized data acquisition. Zuo Z, Cao L, Nothia LF, Mohimani H Bioinformatics (Oxford, England) 34252948 Bioinformatics 2021 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/34252948
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Nanoscale Structures and Materials from the Self-assembly of Polypeptides and DNA. Bernal-Chanchavac J, Al-Amin M, Stephanopoulos N Current topics in medicinal chemistry 34911426 Curr Top Med Chem 2022 https://www.ncbi.nlm.nih.gov/pubmed/34911426
Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals. Simmons CR, Buchberger A, Henry SJW, Novacek A, Fahmi NE, MacCulloch T, Stephanopoulos N, Yan H Journal of the American Chemical Society 37987645 J Am Chem Soc 2023 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/37987645
Self-Assembly of Hybrid Peptide-DNA Nanostructures using Homotrimeric Coiled-Coil/Nucleic Acid Building Blocks. Buchberger A, Al-Amin M, Simmons CR, Stephanopoulos N Chembiochem : a European journal of chemical biology 37099451 Chembiochem 2023 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/37099451
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Protein Corona Inhibits Endosomal Escape of Functionalized DNA Nanostructures in Living Cells. Smolková B, MacCulloch T, Rockwood TF, Liu M, Henry SJW, Frtús A, Uzhytchak M, Lunova M, Hof M, Jurkiewicz P, Dejneka A, Stephanopoulos N, Lunov O ACS applied materials & interfaces 34569777 ACS Appl Mater Interfaces 2021 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/34569777
CytoDirect: A Nucleic Acid Nanodevice for Specific and Efficient Delivery of Functional Payloads to the Cytoplasm. Yu L, Xu Y, Al-Amin M, Jiang S, Sample M, Prasad A, Stephanopoulos N, Šulc P, Yan H Journal of the American Chemical Society 38055928 J Am Chem Soc 2023 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/38055928
High-Affinity Host-Guest Recognition for Efficient Assembly and Enzymatic Responsiveness of DNA Nanostructures. Narayanan RP, Prasad A, Buchberger A, Zou L, Bernal-Chanchavac J, MacCulloch T, Fahmi NE, Yan H, Zhang F, Webber MJ, Stephanopoulos N Small (Weinheim an der Bergstrasse, Germany) 37849034 Small 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/37849034
Construction of Reconfigurable and Polymorphic DNA Origami Assemblies with Coiled-Coil Patches and Patterns. Teng T, Bernal-Chanchavac J, Stephanopoulos N, Castro CE Advanced science (Weinheim, Baden-Wurttemberg, Germany) 38459678 Adv Sci (Weinh) 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38459678
Using dynamic biomaterials to study the temporal role of bioactive peptides during osteogenesis. Fumasi FM, MacCulloch T, Bernal-Chanchavac J, Stephanopoulos N, Holloway JL Biomaterials advances 38096646 Biomater Adv 2024 Feb https://www.ncbi.nlm.nih.gov/pubmed/38096646
Peptide-coated DNA nanostructures as a platform for control of lysosomal function in cells. Elblová P, Lunova M, Henry SJW, Tu X, Calé A, Dejneka A, Havelková J, Petrenko Y, Jirsa M, Stephanopoulos N, Lunov O Chemical engineering journal (Lausanne, Switzerland : 1996) 39372137 Chem Eng J 2024 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/39372137
Site-specific arrangement and structure determination of minor groove binding molecules in self-assembled three-dimensional DNA crystals. Simmons CR, Buchberger A, Henry SJW, Novacek A, Fahmi NE, MacCulloch T, Stephanopoulos N, Yan H bioRxiv : the preprint server for biology 37873139 bioRxiv 2023 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/37873139
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Coding functions of "noncoding" RNAs. Wei LH, Guo JU Science (New York, N.Y.) 32139529 Science 2020 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/32139529
Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions. Lee PJ, Sun Y, Soares AR, Fai C, Picciotto MR, Guo JU Molecular cell 39317199 Mol Cell 2024 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/39317199
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Regulation of nonsense-mediated mRNA decay in neural development and disease. Lee PJ, Yang S, Sun Y, Guo JU Journal of molecular cell biology 33783512 J Mol Cell Biol 2021 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/33783512
Stress promotes RNA G-quadruplex folding in human cells. Kharel P, Fay M, Manasova EV, Anderson PJ, Kurkin AV, Guo JU, Ivanov P Nature communications 36639366 Nat Commun 2023 Jan 13 https://www.ncbi.nlm.nih.gov/pubmed/36639366
Restriction of SARS-CoV-2 Replication by Targeting Programmed -1 Ribosomal Frameshifting In Vitro. Sun Y, Abriola L, Surovtseva YV, Lindenbach BD, Guo JU bioRxiv : the preprint server for biology 33106809 bioRxiv 2020 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/33106809
Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions. Lee PJ, Soares AR, Sun Y, Fai C, Picciotto MR, Guo JU bioRxiv : the preprint server for biology 38405936 bioRxiv 2024 Feb 17 https://www.ncbi.nlm.nih.gov/pubmed/38405936
Internal sensory neurons regulate stage-specific growth in Drosophila. Ohhara Y, Yamanaka N Development (Cambridge, England) 36227580 Development 2022 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/36227580
Steroid Hormone Entry into the Brain Requires a Membrane Transporter in Drosophila. Okamoto N, Yamanaka N Current biology : CB 31928869 Curr Biol 2020 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/31928869
Essential functions of mosquito ecdysone importers in development and reproduction. Hun LV, Okamoto N, Imura E, Maxson R, Bittar R, Yamanaka N Proceedings of the National Academy of Sciences of the United States of America 35696563 Proc Natl Acad Sci U S A 2022 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/35696563
Steroid hormone signaling: What we can learn from insect models. Okamoto N, Fujinaga D, Yamanaka N Vitamins and hormones 37717997 Vitam Horm 2023 https://www.ncbi.nlm.nih.gov/pubmed/37717997
Functional characterization of eicosanoid signaling in Drosophila development. Fujinaga D, Nolan C, Yamanaka N bioRxiv : the preprint server for biology 39868285 bioRxiv 2025 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/39868285
A Neuropeptide Signaling Network That Regulates Developmental Timing and Systemic Growth in Drosophila. Ohhara Y, Blick M, Park D, Yoon SE, Kim YJ, Pankratz MJ, O'Connor MB, Yamanaka N The Journal of comparative neurology 39415613 J Comp Neurol 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/39415613
Deep mutational scanning and machine learning reveal structural and molecular rules governing allosteric hotspots in homologous proteins. Leander M, Liu Z, Cui Q, Raman S eLife 36226916 Elife 2022 Oct 13 https://www.ncbi.nlm.nih.gov/pubmed/36226916
De novo design of programmable inducible promoters. Liu X, Gupta STP, Bhimsaria D, Reed JL, Rodríguez-Martínez JA, Ansari AZ, Raman S Nucleic acids research 31552424 Nucleic Acids Res 2019 Nov 4 https://www.ncbi.nlm.nih.gov/pubmed/31552424
A parametrized two-domain thermodynamic model explains diverse mutational effects on protein allostery. Liu Z, Gillis T, Raman S, Cui Q bioRxiv : the preprint server for biology 37662419 bioRxiv 2024 Feb 14 https://www.ncbi.nlm.nih.gov/pubmed/37662419
Large-scale discovery of chromatin dysregulation induced by oncofusions and other protein-coding variants. Frenkel M, Corban JE, Hujoel MLA, Morris Z, Raman S Nature biotechnology 39048711 Nat Biotechnol 2024 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/39048711
Functional plasticity and evolutionary adaptation of allosteric regulation. Leander M, Yuan Y, Meger A, Cui Q, Raman S Proceedings of the National Academy of Sciences of the United States of America 32999067 Proc Natl Acad Sci U S A 2020 Oct 13 https://www.ncbi.nlm.nih.gov/pubmed/32999067
Discovering chromatin dysregulation induced by protein-coding perturbations at scale. Frenkel M, Hujoel MLA, Morris Z, Raman S bioRxiv : the preprint server for biology 37781603 bioRxiv 2023 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/37781603
Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors. Meger AT, Spence MA, Sandhu M, Matthews D, Chen J, Jackson CJ, Raman S Cell systems 38537640 Cell Syst 2024 Apr 17 https://www.ncbi.nlm.nih.gov/pubmed/38537640
A parameterized two-domain thermodynamic model explains diverse mutational effects on protein allostery. Liu Z, Gillis TG, Raman S, Cui Q eLife 38836839 Elife 2024 Jun 5 https://www.ncbi.nlm.nih.gov/pubmed/38836839
Multidimensional super-resolution microscopy unveils nanoscale surface aggregates in the aging of FUS condensates. He C, Wu CY, Li W, Xu K bioRxiv : the preprint server for biology 37503034 bioRxiv 2023 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/37503034
Single-Molecule Displacement Mapping Unveils Sign-Asymmetric Protein Charge Effects on Intraorganellar Diffusion. Xiang L, Yan R, Chen K, Li W, Xu K Nano letters 36802676 Nano Lett 2023 Mar 8 https://www.ncbi.nlm.nih.gov/pubmed/36802676
Probing Nanoscale Diffusional Heterogeneities in Cellular Membranes through Multidimensional Single-Molecule and Super-Resolution Microscopy. Yan R, Chen K, Xu K Journal of the American Chemical Society 33084318 J Am Chem Soc 2020 Nov 4 https://www.ncbi.nlm.nih.gov/pubmed/33084318
The endoplasmic reticulum adopts two distinct tubule forms. Wang B, Zhao Z, Xiong M, Yan R, Xu K Proceedings of the National Academy of Sciences of the United States of America 35471903 Proc Natl Acad Sci U S A 2022 May 3 https://www.ncbi.nlm.nih.gov/pubmed/35471903
Single-Molecule Spectroscopy and Super-Resolution Mapping of Physicochemical Parameters in Living Cells. Steves MA, He C, Xu K Annual review of physical chemistry 38360526 Annu Rev Phys Chem 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38360526
Single-molecule displacement mapping unveils nanoscale heterogeneities in intracellular diffusivity. Xiang L, Chen K, Yan R, Li W, Xu K Nature methods 32203387 Nat Methods 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32203387
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis. Tian R, Abarientos A, Hong J, Hashemi SH, Yan R, Dräger N, Leng K, Nalls MA, Singleton AB, Xu K, Faghri F, Kampmann M Nature neuroscience 34031600 Nat Neurosci 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34031600
Single Molecules Are Your Quanta: A Bottom-Up Approach toward Multidimensional Super-resolution Microscopy. Xiang L, Chen K, Xu K ACS nano 34304562 ACS Nano 2021 Aug 24 https://www.ncbi.nlm.nih.gov/pubmed/34304562
Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing. Chen K, Yan R, Xiang L, Xu K Light, science & applications 33963178 Light Sci Appl 2021 May 8 https://www.ncbi.nlm.nih.gov/pubmed/33963178
SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport. Yan R, Chen K, Wang B, Xu K Developmental cell 35051356 Dev Cell 2022 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/35051356
Vertebrate cells differentially interpret ciliary and extraciliary cAMP. Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF Cell 33932338 Cell 2021 May 27 https://www.ncbi.nlm.nih.gov/pubmed/33932338
Multidimensional Super-Resolution Microscopy Unveils Nanoscale Surface Aggregates in the Aging of FUS Condensates. He C, Wu CY, Li W, Xu K Journal of the American Chemical Society 37782826 J Am Chem Soc 2023 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/37782826
Displacement Statistics of Unhindered Single Molecules Show no Enhanced Diffusion in Enzymatic Reactions. Choi AA, Park HH, Chen K, Yan R, Li W, Xu K Journal of the American Chemical Society 35258969 J Am Chem Soc 2022 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/35258969
Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells. Jin M, Shirazinejad C, Wang B, Yan A, Schöneberg J, Upadhyayula S, Xu K, Drubin DG Nature communications 35732852 Nat Commun 2022 Jun 22 https://www.ncbi.nlm.nih.gov/pubmed/35732852
Super-multiplexing excitation spectral microscopy with multiple fluorescence bands. Chen K, Li W, Xu K Biomedical optics express 36733753 Biomed Opt Express 2022 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/36733753
Graphene-Enabled, Spatially Controlled Electroporation of Adherent Cells for Live-Cell Super-resolution Microscopy. Moon S, Li W, Hauser M, Xu K ACS nano 32282180 ACS Nano 2020 May 26 https://www.ncbi.nlm.nih.gov/pubmed/32282180
Single-Molecule Displacement Mapping Indicates Unhindered Intracellular Diffusion of Small (≲1 kDa) Solutes. Choi AA, Xiang L, Li W, Xu K Journal of the American Chemical Society 37027457 J Am Chem Soc 2023 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/37027457
Carborane Guests for Cucurbit[7]uril Facilitate Strong Binding and On-Demand Removal. Kataki-Anastasakou A, Axtell JC, Hernandez S, Dziedzic RM, Balaich GJ, Rheingold AL, Spokoyny AM, Sletten EM Journal of the American Chemical Society 33253553 J Am Chem Soc 2020 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/33253553
Cell-surface Labeling via Bioorthogonal Host-Guest Chemistry. Kataki-Anastasakou A, Hernandez S, Sletten EM ACS chemical biology 34669367 ACS Chem Biol 2021 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/34669367
Bioorthogonal chemistry: Bridging chemistry, biology, and medicine. Hartung KM, Sletten EM Chem 39006002 Chem 2023 Aug 10 https://www.ncbi.nlm.nih.gov/pubmed/39006002
Expanding the Scope of Palladium-Catalyzed B - N Cross-Coupling Chemistry in Carboranes. Mu X, Hopp M, Dziedzic RM, Waddington MA, Rheingold AL, Sletten EM, Axtell JC, Spokoyny AM Organometallics 34012188 Organometallics 2020 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/34012188
Arene-Perfluoroarene Interactions in Solution. Lee GY, Hu E, Rheingold AL, Houk KN, Sletten EM The Journal of organic chemistry 34077211 J Org Chem 2021 Jun 18 https://www.ncbi.nlm.nih.gov/pubmed/34077211
A Fluorescent Unnatural Mannosamine Derivative with Enhanced Emission Upon Complexation with Cucurbit[7]uril. Kataki-Anastasakou A, Jia S, Axtell JC, Sletten EM Israel journal of chemistry 37636996 Isr J Chem 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/37636996
A mixture-density-based tandem optimization network for on-demand inverse design of thin-film high reflectors. Unni R, Yao K, Han X, Zhou M, Zheng Y Nanophotonics (Berlin, Germany) 36425324 Nanophotonics 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/36425324
All-optical reconfigurable chiral meta-molecules. Lin L, Lepeshov S, Krasnok A, Jiang T, Peng X, Korgel BA, Alù A, Zheng Y Materials today (Kidlington, England) 31777449 Mater Today (Kidlington) 2019 May https://www.ncbi.nlm.nih.gov/pubmed/31777449
Opto-Thermophoretic Manipulation and Construction of Colloidal Superstructures in Photocurable Hydrogels. Peng X, Li J, Lin L, Liu Y, Zheng Y ACS applied nano materials 31106296 ACS Appl Nano Mater 2018 Aug 24 https://www.ncbi.nlm.nih.gov/pubmed/31106296
Opto-thermophoretic fiber tweezers. Kotnala A, Zheng Y Nanophotonics (Berlin, Germany) 34290953 Nanophotonics 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/34290953
Optothermally Assembled Nanostructures. Li J, Zheng Y Accounts of materials research 34396151 Acc Mater Res 2021 May 28 https://www.ncbi.nlm.nih.gov/pubmed/34396151
Universal optothermal micro/nanoscale rotors. Ding H, Kollipara PS, Kim Y, Kotnala A, Li J, Chen Z, Zheng Y Science advances 35704582 Sci Adv 2022 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/35704582
Thermo-Electro-Mechanics at Individual Particles in Complex Colloidal Systems. Kollipara PS, Lin L, Zheng Y The journal of physical chemistry. C, Nanomaterials and interfaces 32913480 J Phys Chem C Nanomater Interfaces 2019 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/32913480
Optical manipulation and assembly of micro/nanoscale objects on solid substrates. Li J, Alfares A, Zheng Y iScience 35313687 iScience 2022 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/35313687
Room-Temperature Observation of Near-Intrinsic Exciton Linewidth in Monolayer WS(2). Fang J, Yao K, Zhang T, Wang M, Jiang T, Huang S, Korgel BA, Terrones M, Alù A, Zheng Y Advanced materials (Deerfield Beach, Fla.) 35170105 Adv Mater 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35170105
Light-driven C-H activation mediated by 2D transition metal dichalcogenides. Li J, Zhang D, Guo Z, Chen Z, Jiang X, Larson JM, Zhu H, Zhang T, Gu Y, Blankenship BW, Chen M, Wu Z, Huang S, Kostecki R, Minor AM, Grigoropoulos CP, Akinwande D, Terrones M, Redwing JM, Li H, Zheng Y Nature communications 38956055 Nat Commun 2024 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/38956055
Bubble-pen lithography: Fundamentals and applications: Nanoscience: Special Issue Dedicated to Professor Paul S. Weiss. Kollipara PS, Mahendra R, Li J, Zheng Y Aggregate (Hoboken, N.J.) 37441005 Aggregate (Hoboken) 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/37441005
Opto-Thermophoretic Attraction, Trapping, and Dynamic Manipulation of Lipid Vesicles. Hill EH, Li J, Lin L, Liu Y, Zheng Y Langmuir : the ACS journal of surfaces and colloids 30350700 Langmuir 2018 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/30350700
Opto-thermoelectric nanotweezers. Lin L, Wang M, Peng X, Lissek EN, Mao Z, Scarabelli L, Adkins E, Coskun S, Unalan HE, Korgel BA, Liz-Marzán LM, Florin EL, Zheng Y Nature photonics 29785202 Nat Photonics 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29785202
Optical Nanoprinting of Colloidal Particles and Functional Structures. Li J, Hill EH, Lin L, Zheng Y ACS nano 30875190 ACS Nano 2019 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/30875190
Optical Patterning of Two-Dimensional Materials. Kollipara PS, Li J, Zheng Y Research (Washington, D.C.) 32043085 Research (Wash D C) 2020 https://www.ncbi.nlm.nih.gov/pubmed/32043085
Enhancing Surface Capture and Sensing of Proteins with Low-Power Optothermal Bubbles in a Biphasic Liquid. Kim Y, Ding H, Zheng Y Nano letters 32667815 Nano Lett 2020 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/32667815
Directional light emission by electric and magnetic dipoles near a nanosphere: an analytical approach based on the generalized Mie theory. Yao K, Zheng Y Optics letters 33449012 Opt Lett 2021 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/33449012
Directional Modulation of Exciton Emission Using Single Dielectric Nanospheres. Fang J, Wang M, Yao K, Zhang T, Krasnok A, Jiang T, Choi J, Kahn E, Korgel BA, Terrones M, Li X, Alù A, Zheng Y Advanced materials (Deerfield Beach, Fla.) 33837615 Adv Mater 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33837615
Heat-Mediated Optical Manipulation. Chen Z, Li J, Zheng Y Chemical reviews 34797041 Chem Rev 2022 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/34797041
Opto-refrigerative tweezers. Li J, Chen Z, Liu Y, Kollipara PS, Feng Y, Zhang Z, Zheng Y Science advances 34172454 Sci Adv 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34172454
Digital manufacturing of advanced materials: challenges and perspective. Lin L, Kollipara PS, Zheng Y Materials today (Kidlington, England) 32831619 Mater Today (Kidlington) 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/32831619
Sensitivity-Enhancing Strategies in Optical Biosensing. Kim Y, Gonzales J, Zheng Y Small (Weinheim an der Bergstrasse, Germany) 33369864 Small 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33369864
Enhancing Single-Molecule Fluorescence Spectroscopy with Simple and Robust Hybrid Nanoapertures. Kotnala A, Ding H, Zheng Y ACS photonics 35445142 ACS Photonics 2021 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/35445142
Plasmonic Nanotweezers and Nanosensors for Point-of-Care Applications. Peng X, Kotnala A, Rajeeva BB, Wang M, Yao K, Bhatt N, Penley D, Zheng Y Advanced optical materials 34434691 Adv Opt Mater 2021 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/34434691
Investigating water/oil interfaces with opto-thermophoresis. Kim Y, Ding H, Zheng Y Nature communications 35768421 Nat Commun 2022 Jun 29 https://www.ncbi.nlm.nih.gov/pubmed/35768421
Deep Convolutional Mixture Density Network for Inverse Design of Layered Photonic Structures. Unni R, Yao K, Zheng Y ACS photonics 38031541 ACS Photonics 2020 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/38031541
Broadband Forward Light Scattering by Architectural Design of Core-Shell Silicon Particles. De Marco ML, Jiang T, Fang J, Lacomme S, Zheng Y, Baron A, Korgel BA, Barois P, Drisko GL, Aymonier C Advanced functional materials 38031546 Adv Funct Mater 2021 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/38031546
Light-driven C-H activation mediated by 2D transition metal dichalcogenides. Li J, Zhang D, Guo Z, Jiang X, Larson JM, Zhu H, Zhang T, Gu Y, Blankenship B, Chen M, Wu Z, Huang S, Kostecki R, Minor AM, Grigoropoulos CP, Akinwande D, Terrones M, Redwing JM, Li H, Zheng Y Research square 38260621 Res Sq 2024 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/38260621
Digital Assembly of Colloidal Particles for Nanoscale Manufacturing. Kotnala A, Zheng Y Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems 33041521 Part Part Syst Charact 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/33041521
Label-Free Ultrasensitive Detection of Abnormal Chiral Metabolites in Diabetes. Liu Y, Wu Z, Kollipara PS, Montellano R, Sharma K, Zheng Y ACS nano 33760602 ACS Nano 2021 Apr 27 https://www.ncbi.nlm.nih.gov/pubmed/33760602
Liquid Optothermoelectrics: Fundamentals and Applications. Chen Z, Kollipara PS, Ding H, Pughazhendi A, Zheng Y Langmuir : the ACS journal of surfaces and colloids 33410698 Langmuir 2021 Feb 2 https://www.ncbi.nlm.nih.gov/pubmed/33410698
Tunable Chiral Optics in All-Solid-Phase Reconfigurable Dielectric Nanostructures. Li J, Wang M, Wu Z, Li H, Hu G, Jiang T, Guo J, Liu Y, Yao K, Chen Z, Fang J, Fan D, Korgel BA, Alù A, Zheng Y Nano letters 33372805 Nano Lett 2021 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/33372805
Optothermal Manipulations of Colloidal Particles and Living Cells. Lin L, Hill EH, Peng X, Zheng Y Accounts of chemical research 29799720 Acc Chem Res 2018 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/29799720
Nanoradiator-Mediated Deterministic Opto-Thermoelectric Manipulation. Liu Y, Lin L, Bangalore Rajeeva B, Jarrett JW, Li X, Peng X, Kollipara P, Yao K, Akinwande D, Dunn AK, Zheng Y ACS nano 30226980 ACS Nano 2018 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/30226980
Optical nanomanipulation on solid substrates via optothermally-gated photon nudging. Li J, Liu Y, Lin L, Wang M, Jiang T, Guo J, Ding H, Kollipara PS, Inoue Y, Fan D, Korgel BA, Zheng Y Nature communications 31831746 Nat Commun 2019 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/31831746
Opto-thermoelectric speckle tweezers. Kotnala A, Kollipara PS, Zheng Y Nanophotonics (Berlin, Germany) 34290954 Nanophotonics 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/34290954
Decoding Optical Data with Machine Learning. Fang J, Swain A, Unni R, Zheng Y Laser & photonics reviews 34539925 Laser Photon Rev 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/34539925
Tunable Strong Coupling in Transition Metal Dichalcogenide Nanowires. Li J, Yao K, Huang Y, Fang J, Kollipara PS, Fan DE, Zheng Y Advanced materials (Deerfield Beach, Fla.) 35793202 Adv Mater 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/35793202
Programmable Multimodal Optothermal Manipulation of Synthetic Particles and Biological Cells. Ding H, Chen Z, Kollipara PS, Liu Y, Kim Y, Huang S, Zheng Y ACS nano 35816157 ACS Nano 2022 Jul 26 https://www.ncbi.nlm.nih.gov/pubmed/35816157
Opto-Thermophoretic Tweezers and Assembly. Li J, Lin L, Inoue Y, Zheng Y Journal of micro- and nano-manufacturing 35832388 J Micro Nanomanuf 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/35832388
Light-driven single-cell rotational adhesion frequency assay. Liu Y, Ding H, Li J, Lou X, Yang M, Zheng Y eLight 35965781 eLight 2022 https://www.ncbi.nlm.nih.gov/pubmed/35965781
Overcoming Diffusion-Limited Trapping in Nanoaperture Tweezers Using Opto-Thermal-Induced Flow. Kotnala A, Kollipara PS, Li J, Zheng Y Nano letters 31834809 Nano Lett 2020 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/31834809
Atomistic modeling and rational design of optothermal tweezers for targeted applications. Ding H, Kollipara PS, Lin L, Zheng Y Nano research 35475031 Nano Res 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/35475031
Opto-thermoelectric microswimmers. Peng X, Chen Z, Kollipara PS, Liu Y, Fang J, Lin L, Zheng Y Light, science & applications 32864116 Light Sci Appl 2020 https://www.ncbi.nlm.nih.gov/pubmed/32864116
Optothermophoretic Manipulation of Colloidal Particles in Nonionic Liquids. Peng X, Lin L, Hill EH, Kunal P, Humphrey SM, Zheng Y The journal of physical chemistry. C, Nanomaterials and interfaces 30766650 J Phys Chem C Nanomater Interfaces 2018 Oct 25 https://www.ncbi.nlm.nih.gov/pubmed/30766650
Suppressing material loss in the visible and near-infrared range for functional nanophotonics using bandgap engineering. Wang M, Krasnok A, Lepeshov S, Hu G, Jiang T, Fang J, Korgel BA, Alù A, Zheng Y Nature communications 33028825 Nat Commun 2020 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/33028825
Controlling the polarization of chiral dipolar emission with a spherical dielectric nanoantenna. Yao K, Zheng Y The Journal of chemical physics 34911301 J Chem Phys 2021 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/34911301
Opto-Thermocapillary Nanomotors on Solid Substrates. Li J, Kollipara PS, Liu Y, Yao K, Liu Y, Zheng Y ACS nano 35594375 ACS Nano 2022 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/35594375
Intelligent nanophotonics: merging photonics and artificial intelligence at the nanoscale. Yao K, Unni R, Zheng Y Nanophotonics (Berlin, Germany) 34290952 Nanophotonics 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/34290952
Opto-Thermoelectric Tweezers: Principles and Applications. Pughazhendi A, Chen Z, Wu Z, Li J, Zheng Y Frontiers in physics 38031585 Front Phys 2020 https://www.ncbi.nlm.nih.gov/pubmed/38031585
Influenza A virus rapidly adapts particle shape to environmental pressures. Partlow EA, Jaeggi-Wong A, Planitzer SD, Berg N, Li Z, Ivanovic T Nature microbiology 39929974 Nat Microbiol 2025 Mar https://www.ncbi.nlm.nih.gov/pubmed/39929974
Hemagglutinin Stability Determines Influenza A Virus Susceptibility to a Broad-Spectrum Fusion Inhibitor Arbidol. Li Z, Li T, Liu M, Ivanovic T ACS infectious diseases 35819162 ACS Infect Dis 2022 Aug 12 https://www.ncbi.nlm.nih.gov/pubmed/35819162
The shape of pleomorphic virions determines resistance to cell-entry pressure. Li T, Li Z, Deans EE, Mittler E, Liu M, Chandran K, Ivanovic T Nature microbiology 33737748 Nat Microbiol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33737748
SCINA: A Semi-Supervised Subtyping Algorithm of Single Cells and Bulk Samples. Zhang Z, Luo D, Zhong X, Choi JH, Ma Y, Wang S, Mahrt E, Guo W, Stawiski EW, Modrusan Z, Seshagiri S, Kapur P, Hon GC, Brugarolas J, Wang T Genes 31336988 Genes (Basel) 2019 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/31336988
FBA: feature barcoding analysis for single cell RNA-Seq. Duan J, Hon GC Bioinformatics (Oxford, England) 33999185 Bioinformatics 2021 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/33999185
Breaking enhancers to gain insights into developmental defects. Armendariz DA, Sundarrajan A, Hon GC eLife 37497775 Elife 2023 Jul 27 https://www.ncbi.nlm.nih.gov/pubmed/37497775
Frequent sgRNA-barcode recombination in single-cell perturbation assays. Xie S, Cooley A, Armendariz D, Zhou P, Hon GC PloS one 29874289 PLoS One 2018 https://www.ncbi.nlm.nih.gov/pubmed/29874289
Experimental and Computational Approaches for Single-Cell Enhancer Perturbation Assay. Xie S, Hon GC Methods in molecular biology (Clifton, N.J.) 30758829 Methods Mol Biol 2019 https://www.ncbi.nlm.nih.gov/pubmed/30758829
Rational Reprogramming of Cellular States by Combinatorial Perturbation. Duan J, Li B, Bhakta M, Xie S, Zhou P, Munshi NV, Hon GC Cell reports 31216470 Cell Rep 2019 Jun 18 https://www.ncbi.nlm.nih.gov/pubmed/31216470
A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum. Zhang Y, Li B, Cananzi S, Han C, Wang LL, Zou Y, Fu YX, Hon GC, Zhang CL Proceedings of the National Academy of Sciences of the United States of America 35254903 Proc Natl Acad Sci U S A 2022 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/35254903
Computational identification of clonal cells in single-cell CRISPR screens. Wang Y, Xie S, Armendariz D, Hon GC BMC genomics 35168568 BMC Genomics 2022 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/35168568
CHD-associated enhancers shape human cardiomyocyte lineage commitment. Armendariz DA, Goetsch SC, Sundarrajan A, Sivakumar S, Wang Y, Xie S, Munshi NV, Hon GC eLife 37096669 Elife 2023 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/37096669
Benchmarking and optimizing Perturb-seq in differentiating human pluripotent stem cells. Sivakumar S, Wang Y, Goetsch SC, Pandit V, Wang L, Zhao H, Sundarrajan A, Armendariz D, Takeuchi C, Nzima M, Chen WC, Dederich AE, El Hayek L, Gao T, Ghazawi R, Gogate A, Kaur K, Kim HB, McCoy MK, Niederstrasser H, Oura S, Pinzon-Arteaga CA, Sanghvi M, Schmitz DA, Yu L, Zhang Y, Zhou Q, Kraus WL, Xu L, Wu J, Posner BA, Chahrour MH, Hon GC, Munshi NV bioRxiv : the preprint server for biology 39896670 bioRxiv 2025 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/39896670
Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice. Hepler C, Shan B, Zhang Q, Henry GH, Shao M, Vishvanath L, Ghaben AL, Mobley AB, Strand D, Hon GC, Gupta RK eLife 30265241 Elife 2018 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/30265241
Single-Cell Genomics: Catalyst for Cell Fate Engineering. Li B, Hon GC Frontiers in bioengineering and biotechnology 34733831 Front Bioeng Biotechnol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34733831
Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption. Cooley A, Madhukaran S, Stroebele E, Colon Caraballo M, Wang L, Akgul Y, Hon GC, Mahendroo M iScience 36718364 iScience 2023 Feb 17 https://www.ncbi.nlm.nih.gov/pubmed/36718364
Global Analysis of Enhancer Targets Reveals Convergent Enhancer-Driven Regulatory Modules. Xie S, Armendariz D, Zhou P, Duan J, Hon GC Cell reports 31775028 Cell Rep 2019 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/31775028
A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra. Henry GH, Malewska A, Joseph DB, Malladi VS, Lee J, Torrealba J, Mauck RJ, Gahan JC, Raj GV, Roehrborn CG, Hon GC, MacConmara MP, Reese JC, Hutchinson RC, Vezina CM, Strand DW Cell reports 30566875 Cell Rep 2018 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/30566875
Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition. Bhattacharyya S, Duan J, Wang L, Li B, Bhakta M, Fernandez-Perez A, Hon GC, Munshi NV Scientific reports 30765799 Sci Rep 2019 Feb 14 https://www.ncbi.nlm.nih.gov/pubmed/30765799
Enhancer regulatory networks globally connect non-coding breast cancer loci to cancer genes. Wang Y, Armendariz D, Wang L, Zhao H, Xie S, Hon GC bioRxiv : the preprint server for biology 38045327 bioRxiv 2023 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/38045327
Accurate Classification of Cardiomyopathy Diagnosis by Chromatin Accessibility. Bhattacharyya S, Duan J, Vela RJ, Bhakta M, Bajona P, Mammen PPA, Hon GC, Munshi NV Circulation 36095061 Circulation 2022 Sep 13 https://www.ncbi.nlm.nih.gov/pubmed/36095061
Hormonal modulation of reproduction in Polistes fuscatus social wasps: Dual functions in both ovary development and sexual receptivity. Walton A, Tumulty JP, Toth AL, Sheehan MJ Journal of insect physiology 31705844 J Insect Physiol 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31705844
Expansion and Accelerated Evolution of 9-Exon Odorant Receptors in Polistes Paper Wasps. Legan AW, Jernigan CM, Miller SE, Fuchs MF, Sheehan MJ Molecular biology and evolution 34151983 Mol Biol Evol 2021 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/34151983
Coevolution of cognitive abilities and identity signals in individual recognition systems. Miller SE, Sheehan MJ, Reeve HK Philosophical transactions of the Royal Society of London. Series B, Biological sciences 32420843 Philos Trans R Soc Lond B Biol Sci 2020 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/32420843
Evidence for a selective link between cooperation and individual recognition. Tumulty JP, Miller SE, Van Belleghem SM, Weller HI, Jernigan CM, Vincent S, Staudenraus RJ, Legan AW, Polnaszek TJ, Uy FMK, Walton A, Sheehan MJ Current biology : CB 38065097 Curr Biol 2023 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/38065097
Postural analysis reveals persistent changes in paper wasp foundress behavioral state after conspecific challenge. Legan AW, Vogt CC, Sheehan MJ Ecology and evolution 37664514 Ecol Evol 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37664514
Distinct evolutionary trajectories of V1R clades across mouse species. Miller CH, Campbell P, Sheehan MJ BMC evolutionary biology 32770934 BMC Evol Biol 2020 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/32770934
Strong, but incomplete, mate choice discrimination between two closely related species of paper wasp. Miller SE, Legan AW, Flores ZA, Ng HY, Sheehan MJ Biological journal of the Linnean Society. Linnean Society of London 30853716 Biol J Linn Soc Lond 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30853716
Age and social experience induced plasticity across brain regions of the paper wasp Polistes fuscatus. Jernigan CM, Zaba NC, Sheehan MJ Biology letters 33849349 Biol Lett 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33849349
The promises and challenges of archiving insect behavior and natural history in a changing world. Sheehan MJ, Miller SE Current opinion in insect science 33857642 Curr Opin Insect Sci 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33857642
WASPnest: a worldwide assessment of social Polistine nesting behavior. Miller SE, Bluher SE, Bell E, Cini A, Silva RCD, de Souza AR, Gandia KM, Jandt J, Loope K, Prato A, Pruitt JN, Rankin D, Rankin E, Southon RJ, Uy FMK, Weiner S, Wright CM, Downing H, Gadagkar R, Cristina Lorenzi M, Rusina L, Sumner S, Tibbetts EA, Toth A, Sheehan MJ Ecology 29999519 Ecology 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/29999519
Animal Behavior: Socially Distanced Wasps Learn About Rivals. Sheehan MJ, Goldberg J Current biology : CB 32750347 Curr Biol 2020 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/32750347
Rapid local adaptation linked with phenotypic plasticity. Sun SJ, Catherall AM, Pascoal S, Jarrett BJM, Miller SE, Sheehan MJ, Kilner RM Evolution letters 32774883 Evol Lett 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32774883
Evolutionary dynamics of recent selection on cognitive abilities. Miller SE, Legan AW, Henshaw MT, Ostevik KL, Samuk K, Uy FMK, Sheehan MJ Proceedings of the National Academy of Sciences of the United States of America 31980529 Proc Natl Acad Sci U S A 2020 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/31980529
Dynamic neurogenomic responses to social interactions and dominance outcomes in female paper wasps. Uy FMK, Jernigan CM, Zaba NC, Mehrotra E, Miller SE, Sheehan MJ PLoS genetics 34478434 PLoS Genet 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34478434
Highly Contiguous Genome Assemblies of the Guinea Paper Wasp (Polistes exclamans) and Mischocyttarus mexicanus. Miller SE, Legan AW, Uy FMK, Sheehan MJ Genome biology and evolution 35880292 Genome Biol Evol 2022 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/35880292
Evolutionarily stable investments in recognition systems explain patterns of discrimination failure and success. Sheehan MJ, Reeve HK Philosophical transactions of the Royal Society of London. Series B, Biological sciences 32420853 Philos Trans R Soc Lond B Biol Sci 2020 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/32420853
Fine-Scale Population Structure but Limited Genetic Differentiation in a Cooperatively Breeding Paper Wasp. Bluher SE, Miller SE, Sheehan MJ Genome biology and evolution 32271866 Genome Biol Evol 2020 May 1 https://www.ncbi.nlm.nih.gov/pubmed/32271866
Color is necessary for face discrimination in the Northern paper wasp, Polistes fuscatus. Jernigan CM, Stafstrom JA, Zaba NC, Vogt CC, Sheehan MJ Animal cognition 36245014 Anim Cogn 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/36245014
Sex differences in deleterious genetic variants in a haplodiploid social insect. Miller SE, Sheehan MJ Molecular ecology 37350360 Mol Ecol 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37350360
Detergent headgroups control TolC folding in vitro. Ikujuni AP, Budiardjo SJ, Dhar R, Slusky JSG Biophysical journal 36772796 Biophys J 2023 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/36772796
Efflux Pumps Represent Possible Evolutionary Convergence onto the β-Barrel Fold. Franklin MW, Nepomnyachiy S, Feehan R, Ben-Tal N, Kolodny R, Slusky JSG Structure (London, England : 1993) 30057025 Structure 2018 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/30057025
Evolutionary Engineering a Larger Porin Using a Loop-to-Hairpin Mechanism. Dhar R, Bowman AM, Hatungimana B, Sg Slusky J Journal of molecular biology 37769963 J Mol Biol 2023 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/37769963
Evolutionary engineering a larger porin using a loop-to-hairpin mechanism. Dhar R, Bowman AM, Hatungimana B, Slusky JS bioRxiv : the preprint server for biology 37398247 bioRxiv 2023 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/37398247
MAHOMES II: A webserver for predicting if a metal binding site is enzymatic. Feehan R, Copeland M, Franklin MW, Slusky JSG Protein science : a publication of the Protein Society 36916762 Protein Sci 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36916762
High-Yield Preparation of Outer Membrane Protein Efflux Pumps by in Vitro Refolding is Concentration Dependent. Budiardjo SJ, Ikujuni AP, Firlar E, Cordova A, Kaelber JT, Slusky JSG The Journal of membrane biology 33462665 J Membr Biol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33462665
Machine learning differentiates enzymatic and non-enzymatic metals in proteins. Feehan R, Franklin MW, Slusky JSG Nature communications 34140507 Nat Commun 2021 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/34140507
MAHOMES II: A webserver for predicting if a metal binding site is enzymatic. Feehan R, Copeland M, Franklin MW, Slusky JSG bioRxiv : the preprint server for biology 36945603 bioRxiv 2023 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/36945603
Tight Turns of Outer Membrane Proteins: An Analysis of Sequence, Structure, and Hydrogen Bonding. Franklin MW, Slusky JSG Journal of molecular biology 29944853 J Mol Biol 2018 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/29944853
Evolutionary pathways of repeat protein topology in bacterial outer membrane proteins. Franklin MW, Nepomnyachyi S, Feehan R, Ben-Tal N, Kolodny R, Slusky JS eLife 30489257 Elife 2018 Nov 29 https://www.ncbi.nlm.nih.gov/pubmed/30489257
Machine learning for enzyme engineering, selection and design. Feehan R, Montezano D, Slusky JSG Protein engineering, design & selection : PEDS 34296736 Protein Eng Des Sel 2021 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/34296736
General features of transmembrane beta barrels from a large database. Montezano D, Bernstein R, Copeland MM, Slusky JSG Proceedings of the National Academy of Sciences of the United States of America 37432995 Proc Natl Acad Sci U S A 2023 Jul 18 https://www.ncbi.nlm.nih.gov/pubmed/37432995
Membrane Barrels Are Taller, Fatter, Inside-Out Soluble Barrels. Dhar R, Feehan R, Slusky JSG The journal of physical chemistry. B 33797916 J Phys Chem B 2021 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/33797916
Colicin E1 opens its hinge to plug TolC. Budiardjo SJ, Stevens JJ, Calkins AL, Ikujuni AP, Wimalasena VK, Firlar E, Case DA, Biteen JS, Kaelber JT, Slusky JSG eLife 35199644 Elife 2022 Feb 24 https://www.ncbi.nlm.nih.gov/pubmed/35199644
Outer membrane protein evolution. Dhar R, Slusky JS Current opinion in structural biology 33493965 Curr Opin Struct Biol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33493965
Discovery and Characterization of Two Folded Intermediates for Outer Membrane Protein TolC Biogenesis. Ikujuni AP, Dhar R, Cordova A, Bowman AM, Noga S, Slusky JSG Journal of molecular biology 38871177 J Mol Biol 2024 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/38871177
Observation of conformational dynamics in single light-harvesting proteins from cryptophyte algae. Moya R, Norris AC, Spangler LC, Scholes GD, Schlau-Cohen GS The Journal of chemical physics 35868944 J Chem Phys 2022 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/35868944
Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor. Gordon JB, Hoffman MC, Troiano JM, Li M, Hazelbauer GL, Schlau-Cohen GS ACS chemical biology 34647725 ACS Chem Biol 2021 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/34647725
Ligand-induced transmembrane conformational coupling in monomeric EGFR. Srinivasan S, Regmi R, Lin X, Dreyer CA, Chen X, Quinn SD, He W, Coleman MA, Carraway KL 3rd, Zhang B, Schlau-Cohen GS Nature communications 35794108 Nat Commun 2022 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/35794108
Phosphorylation-Dependent Conformations of the Disordered Carboxyl-Terminus Domain in the Epidermal Growth Factor Receptor. Regmi R, Srinivasan S, Latham AP, Kukshal V, Cui W, Zhang B, Bose R, Schlau-Cohen GS The journal of physical chemistry letters 33179922 J Phys Chem Lett 2020 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/33179922
Nanoscale 3D spatial addressing and valence control of quantum dots using wireframe DNA origami. Chen C, Wei X, Parsons MF, Guo J, Banal JL, Zhao Y, Scott MN, Schlau-Cohen GS, Hernandez R, Bathe M Nature communications 35999227 Nat Commun 2022 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/35999227
Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single-molecule pump-probe spectroscopy. Moya R, Norris AC, Kondo T, Schlau-Cohen GS Nature chemistry 34992285 Nat Chem 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/34992285
Tuning Optical Absorption and Emission Using Strongly Coupled Dimers in Programmable DNA Scaffolds. Hart SM, Wang X, Guo J, Bathe M, Schlau-Cohen GS The journal of physical chemistry letters 35175058 J Phys Chem Lett 2022 Feb 24 https://www.ncbi.nlm.nih.gov/pubmed/35175058
Spectrally-tunable femtosecond single-molecule pump-probe spectroscopy. Moya R, Kondo T, Norris AC, Schlau-Cohen GS Optics express 34614960 Opt Express 2021 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/34614960
Evolving artificial metalloenzymes via random mutagenesis. Yang H, Swartz AM, Park HJ, Srivastava P, Ellis-Guardiola K, Upp DM, Lee G, Belsare K, Gu Y, Zhang C, Moellering RE, Lewis JC Nature chemistry 29461523 Nat Chem 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29461523
Chemical probes for spatially resolved measurement of active enzymes in single cells. Li G, Moellering RE Methods in enzymology 31668232 Methods Enzymol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31668232
Versatile Peptide Macrocyclization with Diels-Alder Cycloadditions. Montgomery JE, Donnelly JA, Fanning SW, Speltz TE, Shangguan X, Coukos JS, Greene GL, Moellering RE Journal of the American Chemical Society 31523967 J Am Chem Soc 2019 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/31523967
Diels-Alder Cycloadditions for Peptide Macrocycle Formation. Montgomery JE, Moellering RE Methods in molecular biology (Clifton, N.J.) 34596848 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/34596848
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaženović I, Lastra RR, Curtis M, Yamada SD, Perets R, McGregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel E Nature 31043742 Nature 2019 May https://www.ncbi.nlm.nih.gov/pubmed/31043742
High throughput discovery of functional protein modifications by Hotspot Thermal Profiling. Huang JX, Lee G, Cavanaugh KE, Chang JW, Gardel ML, Moellering RE Nature methods 31384043 Nat Methods 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31384043
Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains. Speltz TE, Qiao Z, Swenson CS, Shangguan X, Coukos JS, Lee CW, Thomas DM, Santana J, Fanning SW, Greene GL, Moellering RE Nature biotechnology 36302987 Nat Biotechnol 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/36302987
Photoproximity Profiling of Protein-Protein Interactions in Cells. McCutcheon DC, Lee G, Carlos A, Montgomery JE, Moellering RE Journal of the American Chemical Society 31820968 J Am Chem Soc 2020 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/31820968
Chemoproteomic Profiling of Phosphoaspartate Modifications in Prokaryotes. Chang JW, Montgomery JE, Lee G, Moellering RE Angewandte Chemie (International ed. in English) 30231186 Angew Chem Int Ed Engl 2018 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/30231186
Family-Wide Photoproximity Profiling of Integrin Protein Social Networks in Cancer. Carlos AJ, Yang D, Thomas DM, Huang S, Harter KI, Moellering RE bioRxiv : the preprint server for biology 39345550 bioRxiv 2024 Sep 22 https://www.ncbi.nlm.nih.gov/pubmed/39345550
A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Bollong MJ, Lee G, Coukos JS, Yun H, Zambaldo C, Chang JW, Chin EN, Ahmad I, Chatterjee AK, Lairson LL, Schultz PG, Moellering RE Nature 30323285 Nature 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30323285
Ultrasensitive, multiplexed chemoproteomic profiling with soluble activity-dependent proximity ligation. Li G, Eckert MA, Chang JW, Montgomery JE, Chryplewicz A, Lengyel E, Moellering RE Proceedings of the National Academy of Sciences of the United States of America 31591248 Proc Natl Acad Sci U S A 2019 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/31591248
A Concise, Modular Antibody-Oligonucleotide Conjugation Strategy Based on Disuccinimidyl Ester Activation Chemistry. Li G, Moellering RE Chembiochem : a European journal of chemical biology 30767357 Chembiochem 2019 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/30767357
An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells. Li G, Montgomery JE, Eckert MA, Chang JW, Tienda SM, Lengyel E, Moellering RE Nature communications 29176560 Nat Commun 2017 Nov 24 https://www.ncbi.nlm.nih.gov/pubmed/29176560
Label-Free Vibrational and Quantitative Phase Microscopy Reveals Remarkable Pathogen-Induced Morphomolecular Divergence in Tumor-Derived Cells. Liu Z, Parida S, Wu S, Sears CL, Sharma D, Barman I ACS sensors 35583030 ACS Sens 2022 May 27 https://www.ncbi.nlm.nih.gov/pubmed/35583030
Label-Free Raman Spectroscopy Reveals Signatures of Radiation Resistance in the Tumor Microenvironment. Paidi SK, Diaz PM, Dadgar S, Jenkins SV, Quick CM, Griffin RJ, Dings RPM, Rajaram N, Barman I Cancer research 30819665 Cancer Res 2019 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/30819665
Ultrasensitive Detection of Hepatotoxic Microcystin Production from Cyanobacteria Using Surface-Enhanced Raman Scattering Immunosensor. Li M, Paidi SK, Sakowski E, Preheim S, Barman I ACS sensors 30990314 ACS Sens 2019 May 24 https://www.ncbi.nlm.nih.gov/pubmed/30990314
Reagent-Free and Rapid Assessment of T Cell Activation State Using Diffraction Phase Microscopy and Deep Learning. Karandikar SH, Zhang C, Meiyappan A, Barman I, Finck C, Srivastava PK, Pandey R Analytical chemistry 30741527 Anal Chem 2019 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/30741527
Self-Folding Hybrid Graphene Skin for 3D Biosensing. Xu W, Paidi SK, Qin Z, Huang Q, Yu CH, Pagaduan JV, Buehler MJ, Barman I, Gracias DH Nano letters 30433789 Nano Lett 2019 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/30433789
Mapping the genetic basis of breast microcalcifications and their role in metastasis. Rizwan A, Paidi SK, Zheng C, Cheng M, Barman I, Glunde K Scientific reports 30038419 Sci Rep 2018 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/30038419
Decoding Live Cell Interactions with Multi-Nanoparticle Systems: Differential Implications for Uptake, Trafficking, and Gene Regulation. Liang L, Liu Z, Barman I ACS applied materials & interfaces 31436085 ACS Appl Mater Interfaces 2019 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/31436085
Shedding Light on the Trehalose-Enabled Mucopermeation of Nanoparticles with Label-Free Raman Spectroscopy. Siddhanta S, Bhattacharjee S, Harrison SM, Scholz D, Barman I Small (Weinheim an der Bergstrasse, Germany) 31267720 Small 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31267720
Optical properties of symmetry-breaking tetrahedral nanoparticles. Zheng P , Paria D , Wang H , Li M , Barman I Nanoscale 31830188 Nanoscale 2020 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/31830188
Rapid, Label-free Optical Spectroscopy Platform for Diagnosis of Heparin-Induced Thrombocytopenia. Huang Z, Siddhanta S, Zheng G, Kickler T, Barman I Angewandte Chemie (International ed. in English) 31972060 Angew Chem Int Ed Engl 2020 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/31972060
Label-free spectrochemical probe for determination of hemoglobin glycation in clinical blood samples. Pandey R, Singh SP, Zhang C, Horowitz GL, Lue N, Galindo L, Dasari RR, Barman I Journal of biophotonics 29726123 J Biophotonics 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/29726123
Pyramidal hyperbolic metasurfaces enhance spontaneous emission of nitrogen-vacancy centers in nanodiamond. Zheng P, Liang L, Arora S, Ray K, Semancik S, Barman I Advanced optical materials 37920689 Adv Opt Mater 2023 Mar 17 https://www.ncbi.nlm.nih.gov/pubmed/37920689
Coarse Raman and optical diffraction tomographic imaging enable label-free phenotyping of isogenic breast cancer cells of varying metastatic potential. Paidi SK, Shah V, Raj P, Glunde K, Pandey R, Barman I Biosensors & bioelectronics 33272866 Biosens Bioelectron 2021 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/33272866
Towards rational design and optimization of near-field enhancement and spectral tunability of hybrid core-shell plasmonic nanoprobes. Paria D, Zhang C, Barman I Scientific reports 31690763 Sci Rep 2019 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/31690763
A Programmable DNA-Silicification-Based Nanocavity for Single-Molecule Plasmonic Sensing. Liang L, Zheng P, Zhang C, Barman I Advanced materials (Deerfield Beach, Fla.) 33458901 Adv Mater 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33458901
Furin-Mediated Self-Assembly of Olsalazine Nanoparticles for Targeted Raman Imaging of Tumors. Yuan Y, Raj P, Zhang J, Siddhanta S, Barman I, Bulte JWM Angewandte Chemie (International ed. in English) 33325142 Angew Chem Int Ed Engl 2021 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/33325142
Silver-Coated Disordered Silicon Nanowires Provide Highly Sensitive Label-Free Glycated Albumin Detection through Molecular Trapping and Plasmonic Hotspot Formation. Paria D, Convertino A, Mussi V, Maiolo L, Barman I Advanced healthcare materials 33236490 Adv Healthc Mater 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33236490
Identification and Staging of B-Cell Acute Lymphoblastic Leukemia Using Quantitative Phase Imaging and Machine Learning. Ayyappan V, Chang A, Zhang C, Paidi SK, Bordett R, Liang T, Barman I, Pandey R ACS sensors 33092347 ACS Sens 2020 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/33092347
A Dual-Modal Single-Antibody Plasmonic Spectro-Immunoassay for Detection of Small Molecules. Zheng P, Wu L, Raj P, Mizutani T, Szabo M, Hanson WA, Barman I Small (Weinheim an der Bergstrasse, Germany) 35373504 Small 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35373504
Label-Free Morpho-Molecular Imaging for Studying the Differential Interaction of Black Phosphorus with Tumor Cells. Mussi V, Fasolino I, Paria D, De Simone S, Caporali M, Serrano-Ruiz M, Ambrosio L, Barman I, Raucci MG, Convertino A Nanomaterials (Basel, Switzerland) 35745333 Nanomaterials (Basel) 2022 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/35745333
RaMALDI: Enabling simultaneous Raman and MALDI imaging of the same tissue section. Yang E, Kim JH, Tressler CM, Shen XE, Brown DR, Johnson CC, Hahm TH, Barman I, Glunde K Biosensors & bioelectronics 37597501 Biosens Bioelectron 2023 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/37597501
Quantitative Detection of Thyroid-Stimulating Hormone in Patient Samples with a Nanomechanical Single-Antibody Spectro-Immunoassay. Zheng P, Raj P, Wu L, Mizutani T, Szabo M, Hanson WA, Barman I Small (Weinheim an der Bergstrasse, Germany) 37752776 Small 2024 Feb https://www.ncbi.nlm.nih.gov/pubmed/37752776
Molecular Radiative Energy Shifts under Strong Oscillating Fields. Zheng P, Kang J, Paria D, Kang JU, Barman I Small (Weinheim an der Bergstrasse, Germany) 33354911 Small 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33354911
Integration of diffraction phase microscopy and Raman imaging for label-free morpho-molecular assessment of live cells. Pandey R, Zhou R, Bordett R, Hunter C, Glunde K, Barman I, Valdez T, Finck C Journal of biophotonics 30421505 J Biophotonics 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30421505
Composite-Scattering Plasmonic Nanoprobes for Label-Free, Quantitative Biomolecular Sensing. Zhang C, Paria D, Semancik S, Barman I Small (Weinheim an der Bergstrasse, Germany) 31394029 Small 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31394029
Optical diffraction tomography and Raman spectroscopy reveal distinct cellular phenotypes during white and brown adipocyte differentiation. Anantha P, Liu Z, Raj P, Barman I Biosensors & bioelectronics 37207582 Biosens Bioelectron 2023 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/37207582
Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy. Paidi SK, Rodriguez Troncoso J, Raj P, Monterroso Diaz P, Ivers JD, Lee DE, Avaritt NL, Gies AJ, Quick CM, Byrum SD, Tackett AJ, Rajaram N, Barman I Cancer research 34645610 Cancer Res 2021 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/34645610
Raman and quantitative phase imaging allow morpho-molecular recognition of malignancy and stages of B-cell acute lymphoblastic leukemia. Paidi SK, Raj P, Bordett R, Zhang C, Karandikar SH, Pandey R, Barman I Biosensors & bioelectronics 34130086 Biosens Bioelectron 2021 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/34130086
Vibrational spectroscopy for decoding cancer microbiota interactions: Current evidence and future perspective. Liu Z, Parida S, Prasad R, Pandey R, Sharma D, Barman I Seminars in cancer biology 34273519 Semin Cancer Biol 2022 Nov https://www.ncbi.nlm.nih.gov/pubmed/34273519
Raman spectroscopy reveals phenotype switches in breast cancer metastasis. Paidi SK, Troncoso JR, Harper MG, Liu Z, Nguyen KG, Ravindranathan S, Rebello L, Lee DE, Ivers JD, Zaharoff DA, Rajaram N, Barman I Theranostics 35910801 Theranostics 2022 https://www.ncbi.nlm.nih.gov/pubmed/35910801
Hyperspectral Raman Imaging for Automated Recognition of Human Renal Amyloid. Kim JH, Zhang C, Sperati CJ, Barman I, Bagnasco SM The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 37833851 J Histochem Cytochem 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37833851
Non-Perturbative Identification and Subtyping of Amyloidosis in Human Kidney Tissue with Raman Spectroscopy and Machine Learning. Kim JH, Zhang C, Sperati CJ, Bagnasco SM, Barman I Biosensors 37185541 Biosensors (Basel) 2023 Apr 8 https://www.ncbi.nlm.nih.gov/pubmed/37185541
Rapid, quantitative determination of aggregation and particle formation for antibody drug conjugate therapeutics with label-free Raman spectroscopy. Zhang C, Springall JS, Wang X, Barman I Analytica chimica acta 31446951 Anal Chim Acta 2019 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/31446951
Cancer cells display increased migration and deformability in pace with metastatic progression. Liu Z, Lee SJ, Park S, Konstantopoulos K, Glunde K, Chen Y, Barman I FASEB journal : official publication of the Federation of American Societies for Experimental Biology 32463148 FASEB J 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32463148
Surface-enhanced Raman scattering: An emerging tool for sensing cellular function. Tanwar S, Kim JH, Bulte JWM, Barman I Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 35510405 Wiley Interdiscip Rev Nanomed Nanobiotechnol 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35510405
Label-Free Spectroscopic SARS-CoV-2 Detection on Versatile Nanoimprinted Substrates. Paria D, Kwok KS, Raj P, Zheng P, Gracias DH, Barman I Nano letters 35348344 Nano Lett 2022 May 11 https://www.ncbi.nlm.nih.gov/pubmed/35348344
Spectroscopy-Assisted Label-free Molecular Analysis of Live Cell Surface with Vertically Aligned Plasmonic Nanopillars. Zhang C, Siddhanta S, Paria D, Li Y, Zheng C, Barman I Small (Weinheim an der Bergstrasse, Germany) 33942486 Small 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33942486
Plexcitonic Quasi-Bound States in the Continuum. Zheng P, Raj P, Mizutani T, Szabo M, Hanson WA, Barman I Small (Weinheim an der Bergstrasse, Germany) 34411423 Small 2021 Oct https://www.ncbi.nlm.nih.gov/pubmed/34411423
Nanowire Assisted Mechanotyping of Cellular Metastatic Potential. Paria D, Convertino A, Raj P, Glunde K, Chen Y, Barman I Advanced functional materials 34512229 Adv Funct Mater 2021 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/34512229
A Fluorescence and Surface-Enhanced Raman Spectroscopic Dual-Modal Aptasensor for Sensitive Detection of Cyanotoxins. Li M, Lin H, Paidi SK, Mesyngier N, Preheim S, Barman I ACS sensors 32314582 ACS Sens 2020 May 22 https://www.ncbi.nlm.nih.gov/pubmed/32314582
Leveraging Nanomechanical Perturbations in Raman Spectro-Immunoassays to Design a Versatile Serum Biomarker Detection Platform. Zheng P, Raj P, Wu L, Szabo M, Hanson WA, Mizutani T, Barman I Small (Weinheim an der Bergstrasse, Germany) 36117050 Small 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/36117050
Targeted Enzyme Activity Imaging with Quantitative Phase Microscopy. Tanwar S, Wu L, Zahn N, Raj P, Ghaemi B, Chatterjee A, Bulte JWM, Barman I Nano letters 37154678 Nano Lett 2023 May 24 https://www.ncbi.nlm.nih.gov/pubmed/37154678
Engineering vascularized skin-mimetic phantom for non-invasive Raman spectroscopy. Raj P, Wu L, Arora S, Bhatt R, Zuo Y, Fang Z, Verdoold R, Koch T, Gu L, Barman I Sensors and actuators. B, Chemical 38524639 Sens Actuators B Chem 2024 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/38524639
A Smart Intracellular Self-Assembling Bioorthogonal Raman Active Nanoprobe for Targeted Tumor Imaging. Tanwar S, Ghaemi B, Raj P, Singh A, Wu L, Yuan Y, Arifin DR, McMahon MT, Bulte JWM, Barman I Advanced science (Weinheim, Baden-Wurttemberg, Germany) 37715297 Adv Sci (Weinh) 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37715297
Noninvasive morpho-molecular imaging reveals early therapy-induced senescence in human cancer cells. Bresci A, Kim JH, Ghislanzoni S, Manetti F, Wu L, Vernuccio F, Ceconello C, Sorrentino S, Barman I, Bongarzone I, Cerullo G, Vanna R, Polli D Science advances 37703362 Sci Adv 2023 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/37703362
RNA Localization in Bacteria. Fei J, Sharma CM Microbiology spectrum 30191804 Microbiol Spectr 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30191804
Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells. Park S, Prévost K, Heideman EM, Carrier MC, Azam MS, Reyer MA, Liu W, Massé E, Fei J eLife 33616037 Elife 2021 Feb 22 https://www.ncbi.nlm.nih.gov/pubmed/33616037
Mechanical expansion microscopy. Fan Y, Lim Y, Wyss LS, Park S, Xu C, Fu H, Fei J, Hong Y, Wang B Methods in cell biology 33478686 Methods Cell Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33478686
RNA molecules display distinctive organization at nuclear speckles. Paul S, Arias MA, Wen L, Liao SE, Zhang J, Wang X, Regev O, Fei J iScience 38638569 iScience 2024 May 17 https://www.ncbi.nlm.nih.gov/pubmed/38638569
Deoxyribozyme-based method for absolute quantification of N(6)-methyladenosine fractions at specific sites of RNA. Bujnowska M, Zhang J, Dai Q, Heideman EM, Fei J The Journal of biological chemistry 32269077 J Biol Chem 2020 May 15 https://www.ncbi.nlm.nih.gov/pubmed/32269077
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices. Lerner E, Barth A, Hendrix J, Ambrose B, Birkedal V, Blanchard SC, Börner R, Sung Chung H, Cordes T, Craggs TD, Deniz AA, Diao J, Fei J, Gonzalez RL, Gopich IV, Ha T, Hanke CA, Haran G, Hatzakis NS, Hohng S, Hong SC, Hugel T, Ingargiola A, Joo C, Kapanidis AN, Kim HD, Laurence T, Lee NK, Lee TH, Lemke EA, Margeat E, Michaelis J, Michalet X, Myong S, Nettels D, Peulen TO, Ploetz E, Razvag Y, Robb NC, Schuler B, Soleimaninejad H, Tang C, Vafabakhsh R, Lamb DC, Seidel CA, Weiss S eLife 33779550 Elife 2021 Mar 29 https://www.ncbi.nlm.nih.gov/pubmed/33779550
An Improved Method for Bacterial Immunofluorescence Staining To Eliminate Antibody Exclusion from the Fixed Nucleoid. Park S, Reyer MA, McLean EL, Liu W, Fei J Biochemistry 31657208 Biochemistry 2019 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/31657208
Continuous active development of super-resolution fluorescence microscopy. Wang Y, Fei J Physical biology 32066124 Phys Biol 2020 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/32066124
Translational T-box riboswitches bind tRNA by modulating conformational flexibility. Campos-Chavez E, Paul S, Zhou Z, Alonso D, Verma AR, Fei J, Mondragón A Nature communications 39097611 Nat Commun 2024 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/39097611
Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency. Wu J, Xiao Y, Liu Y, Wen L, Jin C, Liu S, Paul S, He C, Regev O, Fei J Science advances 39413186 Sci Adv 2024 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/39413186
Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA regulators. Reyer MA, Chennakesavalu S, Heideman EM, Ma X, Bujnowska M, Hong L, Dinner AR, Vanderpool CK, Fei J Cell reports 34592145 Cell Rep 2021 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/34592145
Trophoblast organoids with physiological polarity model placental structure and function. Yang L, Liang P, Yang H, Coyne CB bioRxiv : the preprint server for biology 36711688 bioRxiv 2023 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/36711688
Molecular basis of PIP(2)-dependent regulation of the Ca(2+)-activated chloride channel TMEM16A. Le SC, Jia Z, Chen J, Yang H Nature communications 31434906 Nat Commun 2019 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/31434906
An inner activation gate controls TMEM16F phospholipid scrambling. Le T, Jia Z, Le SC, Zhang Y, Chen J, Yang H Nature communications 31015464 Nat Commun 2019 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/31015464
Conformational plasticity in the selectivity filter of the TRPV2 ion channel. Zubcevic L, Le S, Yang H, Lee SY Nature structural & molecular biology 29728656 Nat Struct Mol Biol 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29728656
Niclosamide potentiates TMEM16A and induces vasoconstriction. Liang P, Wan YCS, Yu K, Hartzell HC, Yang H bioRxiv : the preprint server for biology 37577682 bioRxiv 2023 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/37577682
Endothelial TMEM16F lipid scramblase regulates angiogenesis. Shan KZ, Le T, Liang P, Dong P, Yang H bioRxiv : the preprint server for biology 37645870 bioRxiv 2023 Aug 20 https://www.ncbi.nlm.nih.gov/pubmed/37645870
Trophoblast organoids with physiological polarity model placental structure and function. Yang L, Liang P, Yang H, Coyne CB Journal of cell science 37676312 J Cell Sci 2024 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/37676312
Niclosamide potentiates TMEM16A and induces vasoconstriction. Liang P, Wan YCS, Yu K, Hartzell HC, Yang H The Journal of general physiology 38814250 J Gen Physiol 2024 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/38814250
TMEM16 and OSCA/TMEM63 proteins share a conserved potential to permeate ions and phospholipids. Lowry AJ, Liang P, Song M, Wan Y, Pei ZM, Yang H, Zhang Y eLife 39495104 Elife 2024 Nov 4 https://www.ncbi.nlm.nih.gov/pubmed/39495104
TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development. Zhang Y, Le T, Grabau R, Mohseni Z, Kim H, Natale DR, Feng L, Pan H, Yang H Science advances 32494719 Sci Adv 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32494719
An Additional Ca(2+) Binding Site Allosterically Controls TMEM16A Activation. Le SC, Yang H Cell reports 33378669 Cell Rep 2020 Dec 29 https://www.ncbi.nlm.nih.gov/pubmed/33378669
Corrigendum to "A simple and robust fluorescent labeling method to quantify trophoblast fusion" [Placenta 77 (2019) 16-18]. Zhang Y, Yang H Placenta 31130263 Placenta 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31130263
TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling. Shan KZ, Le T, Liang P, Dong P, Lowry AJ, Kremmyda P, Claesson-Welsh L, Yang H Journal of cell science 38940198 J Cell Sci 2024 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/38940198
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel. Yin Y, Le SC, Hsu AL, Borgnia MJ, Yang H, Lee SY Science (New York, N.Y.) 30733385 Science 2019 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/30733385
A simple and robust fluorescent labeling method to quantify trophoblast fusion. Zhang Y, Yang H Placenta 30827351 Placenta 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30827351
Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel. Zhou Y, Yang H, Cui J, Lingle CJ The Journal of general physiology 29025867 J Gen Physiol 2017 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/29025867
Deciphering and disrupting PIEZO1-TMEM16F interplay in hereditary xerocytosis. Liang P, Zhang Y, Wan YCS, Ma S, Dong P, Lowry AJ, Francis SJ, Khandelwal S, Delahunty M, Telen MJ, Strouse JJ, Arepally GM, Yang H Blood 38033286 Blood 2024 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/38033286
Gating and Regulatory Mechanisms of TMEM16 Ion Channels and Scramblases. Le SC, Liang P, Lowry AJ, Yang H Frontiers in physiology 34867487 Front Physiol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34867487
Structure-Function of TMEM16 Ion Channels and Lipid Scramblases. Le SC, Yang H Advances in experimental medicine and biology 35138612 Adv Exp Med Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/35138612
Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion. Zhang Y, Liang P, Yang L, Shan KZ, Feng L, Chen Y, Liedtke W, Coyne CB, Yang H eLife 35670667 Elife 2022 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/35670667
Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F. Le T, Le SC, Zhang Y, Liang P, Yang H The Journal of biological chemistry 32709749 J Biol Chem 2020 Aug 28 https://www.ncbi.nlm.nih.gov/pubmed/32709749
Drosophila Subdued is a moonlighting transmembrane protein 16 (TMEM16) that transports ions and phospholipids. Le T, Le SC, Yang H The Journal of biological chemistry 30700552 J Biol Chem 2019 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/30700552
Molecular underpinning of intracellular pH regulation on TMEM16F. Liang P, Yang H The Journal of general physiology 33346788 J Gen Physiol 2021 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/33346788
Safety Profile of Rapamycin Perfluorocarbon Nanoparticles for Preventing Cisplatin-Induced Kidney Injury. Zhou Q, Doherty J, Akk A, Springer LE, Fan P, Spasojevic I, Halade GV, Yang H, Pham CTN, Wickline SA, Pan H Nanomaterials (Basel, Switzerland) 35159680 Nanomaterials (Basel) 2022 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/35159680
TMEM16 and OSCA/TMEM63 proteins share a conserved potential to permeate ions and phospholipids. Lowry AJ, Liang P, Song M, Serena Wan YC, Pei ZM, Yang H, Zhang Y bioRxiv : the preprint server for biology 38370744 bioRxiv 2024 Sep 3 https://www.ncbi.nlm.nih.gov/pubmed/38370744
Improved Yield for the Enzymatic Synthesis of Radiolabeled Nicotinamide Adenine Dinucleotide. Eller J, Goyal S, Cambronne XA ACS bio & med chem Au 36820310 ACS Bio Med Chem Au 2023 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/36820310
SLC25A51 is a mammalian mitochondrial NAD(+) transporter. Luongo TS, Eller JM, Lu MJ, Niere M, Raith F, Perry C, Bornstein MR, Oliphint P, Wang L, McReynolds MR, Migaud ME, Rabinowitz JD, Johnson FB, Johnsson K, Ziegler M, Cambronne XA, Baur JA Nature 32906142 Nature 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32906142
Layered mechanisms regulating the human mitochondrial NAD+ transporter SLC25A51. Goyal S, Cambronne XA Biochemical Society transactions 38108469 Biochem Soc Trans 2023 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/38108469
Flow Cytometry Analysis of Free Intracellular NAD(+) Using a Targeted Biosensor. Eller JM, Stewart ML, Slepian AJ, Markwardt S, Wiedrick J, Cohen MS, Goodman RH, Cambronne XA Current protocols in cytometry 30556645 Curr Protoc Cytom 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30556645
Location, Location, Location: Compartmentalization of NAD(+) Synthesis and Functions in Mammalian Cells. Cambronne XA, Kraus WL Trends in biochemical sciences 32595066 Trends Biochem Sci 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32595066
SLC25A51 decouples the mitochondrial NAD(+)/NADH ratio to control proliferation of AML cells. Lu MJ, Busquets J, Impedovo V, Wilson CN, Chan HR, Chang YT, Matsui W, Tiziani S, Cambronne XA Cell metabolism 38354740 Cell Metab 2024 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/38354740
Pharmacological bypass of NAD(+) salvage pathway protects neurons from chemotherapy-induced degeneration. Liu HW, Smith CB, Schmidt MS, Cambronne XA, Cohen MS, Migaud ME, Brenner C, Goodman RH Proceedings of the National Academy of Sciences of the United States of America 30257945 Proc Natl Acad Sci U S A 2018 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/30257945
The mitochondrial NAD(+) transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions. Fu Z, Kim H, Morse PT, Lu MJ, Hüttemann M, Cambronne XA, Zhang K, Zhang R Metabolism: clinical and experimental 35932995 Metabolism 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/35932995
Methods for Using a Genetically Encoded Fluorescent Biosensor to Monitor Nuclear NAD<sup/>. Cohen MS, Stewart ML, Goodman RH, Cambronne XA Methods in molecular biology (Clifton, N.J.) 30097882 Methods Mol Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30097882
Dynamics of SLC25A51 reveal preference for oxidized NAD(+) and substrate led transport. Goyal S, Paspureddi A, Lu MJ, Chan HR, Lyons SN, Wilson CN, Niere M, Ziegler M, Cambronne XA EMBO reports 37575034 EMBO Rep 2023 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/37575034
Meeting report - Mitotic spindle: from living and synthetic systems to theory. Simunić J, Subramanian R Journal of cell science 31477579 J Cell Sci 2019 Sep 2 https://www.ncbi.nlm.nih.gov/pubmed/31477579
Simultaneous Visualization of the Dynamics of Crosslinked and Single Microtubules In Vitro by TIRF Microscopy. Mani N, Marchan MF, Subramanian R Journal of visualized experiments : JoVE 35253794 J Vis Exp 2022 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/35253794
Motor guidance by long-range communication on the microtubule highway. Wijeratne SS, Fiorenza SA, Neary AE, Subramanian R, Betterton MD Proceedings of the National Academy of Sciences of the United States of America 35867749 Proc Natl Acad Sci U S A 2022 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/35867749
Real-Time Visualization of Microtubule and Protofilament-Scale Dynamics in Multi-Microtubule Arrays by Atomic Force Microscopy. Wijeratne SS, Subramanian R Current protocols 37227098 Curr Protoc 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37227098
Active Microphase Separation in Mixtures of Microtubules and Tip-Accumulating Molecular Motors. Lemma B, Mitchell NP, Subramanian R, Needleman DJ, Dogic Z Physical review. X 36643940 Phys Rev X 2022 Jul-Sep https://www.ncbi.nlm.nih.gov/pubmed/36643940
Atomic force microscopy reveals distinct protofilament-scale structural dynamics in depolymerizing microtubule arrays. Wijeratne SS, Marchan MF, Tresback JS, Subramanian R Proceedings of the National Academy of Sciences of the United States of America 35101922 Proc Natl Acad Sci U S A 2022 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/35101922
Micron-scale geometrical features of microtubules as regulators of microtubule organization. Mani N, Wijeratne SS, Subramanian R eLife 34114950 Elife 2021 Jun 11 https://www.ncbi.nlm.nih.gov/pubmed/34114950
Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7. Jiang S, Mani N, Wilson-Kubalek EM, Ku PI, Milligan RA, Subramanian R Developmental cell 31031197 Dev Cell 2019 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/31031197
Differential regulation of single microtubules and bundles by a three-protein module. Mani N, Jiang S, Neary AE, Wijeratne SS, Subramanian R Nature chemical biology 34083810 Nat Chem Biol 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/34083810
Geometry of antiparallel microtubule bundles regulates relative sliding and stalling by PRC1 and Kif4A. Wijeratne S, Subramanian R eLife 30353849 Elife 2018 Oct 24 https://www.ncbi.nlm.nih.gov/pubmed/30353849
Using genome-wide expression compendia to study microorganisms. Lee AJ, Reiter T, Doing G, Oh J, Hogan DA, Greene CS Computational and structural biotechnology journal 36016717 Comput Struct Biotechnol J 2022 https://www.ncbi.nlm.nih.gov/pubmed/36016717
Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19. Landay A, Bartley J, Banerjee D, Hargis G, Haynes L, Keshavarzian A, Kuo CL, Kwon OS, Li S, Li S, Oh J, Ozbolat IT, Ucar D, Xu M, Yao X, Unutmaz D, Kuchel GA Frontiers in aging 35128530 Front Aging 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/35128530
High throughput in situ metagenomic measurement of bacterial replication at ultra-low sequencing coverage. Emiola A, Oh J Nature communications 30470746 Nat Commun 2018 Nov 23 https://www.ncbi.nlm.nih.gov/pubmed/30470746
Strains to go: interactions of the skin microbiome beyond its species. Caldwell R, Zhou W, Oh J Current opinion in microbiology 36242896 Curr Opin Microbiol 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36242896
Bioassay-Driven, Fractionation-Empowered, Focused Metabolomics for Discovering Bacterial Activators of Aryl Hydrocarbon Receptor. Tian H, Wang L, Hardy R, Kozhaya L, Placek L, Fleming E, Oh J, Unutmaz D, Yao X Journal of the American Society for Mass Spectrometry 38308645 J Am Soc Mass Spectrom 2024 Mar 6 https://www.ncbi.nlm.nih.gov/pubmed/38308645
Associations of the skin, oral and gut microbiome with aging, frailty and infection risk reservoirs in older adults. Larson PJ, Zhou W, Santiago A, Driscoll S, Fleming E, Voigt AY, Chun OK, Grady JJ, Kuchel GA, Robison JT, Oh J Nature aging 36398033 Nat Aging 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/36398033
Selective colonization ability of human fecal microbes in different mouse gut environments. Zhou W, Chow KH, Fleming E, Oh J The ISME journal 30442907 ISME J 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30442907
Metagenomic growth rate inferences of strains in situ. Emiola A, Zhou W, Oh J Science advances 32494636 Sci Adv 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32494636
Differential Hairless Mouse Strain-Specific Susceptibility to Skin Cancer and Sunburn. Voigt AY, Michaud M, Tsai KY, Oh J, Sundberg JP The Journal of investigative dermatology 30742806 J Invest Dermatol 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/30742806
State of Residency: Microbial Strain Diversity in the Skin. Kong HH, Oh J The Journal of investigative dermatology 34688614 J Invest Dermatol 2022 May https://www.ncbi.nlm.nih.gov/pubmed/34688614
Cultivation of common bacterial species and strains from human skin, oral, and gut microbiota. Fleming E, Pabst V, Scholar Z, Xiong R, Voigt AY, Zhou W, Hoyt A, Hardy R, Peterson A, Beach R, Ondouah-Nzutchi Y, Dong J, Bateman L, Vernon SD, Oh J BMC microbiology 34649516 BMC Microbiol 2021 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/34649516
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Integration of a multi-omics stem cell differentiation dataset using a dynamical model. van den Berg PR, Bérenger-Currias NMLP, Budnik B, Slavov N, Semrau S PLoS genetics 37167320 PLoS Genet 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37167320
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. Specht H, Emmott E, Petelski AA, Huffman RG, Perlman DH, Serra M, Kharchenko P, Koller A, Slavov N Genome biology 33504367 Genome Biol 2021 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/33504367
Ribosome Stoichiometry: From Form to Function. Emmott E, Jovanovic M, Slavov N Trends in biochemical sciences 30473427 Trends Biochem Sci 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30473427
Voices in methods development. Anikeeva P, Boyden E, Brangwynne C, Cissé II, Fiehn O, Fromme P, Gingras AC, Greene CS, Heard E, Hell SW, Hillman E, Jensen GJ, Karchin R, Kiessling LL, Kleinstiver BP, Knight R, Kukura P, Lancaster MA, Loman N, Looger L, Lundberg E, Luo Q, Miyawaki A, Myers EW Jr, Nolan GP, Picotti P, Reik W, Sauer M, Shalek AK, Shendure J, Slavov N, Tanay A, Troyanskaya O, van Valen D, Wang HW, Yi C, Yin P, Zernicka-Goetz M, Zhuang X Nature methods 31562479 Nat Methods 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31562479
Single cell protein analysis for systems biology. Levy E, Slavov N Essays in biochemistry 30072488 Essays Biochem 2018 Oct 26 https://www.ncbi.nlm.nih.gov/pubmed/30072488
Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics. Huffman RG, Leduc A, Wichmann C, Di Gioia M, Borriello F, Specht H, Derks J, Khan S, Khoury L, Emmott E, Petelski AA, Perlman DH, Cox J, Zanoni I, Slavov N Nature methods 37012480 Nat Methods 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37012480
New Views of Old Proteins: Clarifying the Enigmatic Proteome. Burnum-Johnson KE, Conrads TP, Drake RR, Herr AE, Iyengar R, Kelly RT, Lundberg E, MacCoss MJ, Naba A, Nolan GP, Pevzner PA, Rodland KD, Sechi S, Slavov N, Spraggins JM, Van Eyk JE, Vidal M, Vogel C, Walt DR, Kelleher NL Molecular & cellular proteomics : MCP 35654359 Mol Cell Proteomics 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35654359
DART-ID increases single-cell proteome coverage. Chen AT, Franks A, Slavov N PLoS computational biology 31260443 PLoS Comput Biol 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31260443
Scaling Up Single-Cell Proteomics. Slavov N Molecular & cellular proteomics : MCP 34808355 Mol Cell Proteomics 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34808355
Analyzing Ribosome Remodeling in Health and Disease. Petelski AA, Slavov N Proteomics 32820594 Proteomics 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32820594
Measuring Protein Shapes in Living Cells. Slavov N Journal of proteome research 33988997 J Proteome Res 2021 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/33988997
Approaches for Studying Ribosome Specialization. Emmott E, Jovanovic M, Slavov N Trends in biochemical sciences 30792028 Trends Biochem Sci 2019 May https://www.ncbi.nlm.nih.gov/pubmed/30792028
Single-cell protein analysis by mass spectrometry. Slavov N Current opinion in chemical biology 32599342 Curr Opin Chem Biol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/32599342
Post-transcriptional regulation across human tissues. Franks A, Airoldi E, Slavov N PLoS computational biology 28481885 PLoS Comput Biol 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28481885
Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs. Kern DM, Oh S, Hite RK, Brohawn SG eLife 30775971 Elife 2019 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/30775971
Structural Basis for pH-gating of the K(+) channel TWIK1 at the selectivity filter. Turney TS, Li V, Brohawn SG Nature communications 35680900 Nat Commun 2022 Jun 9 https://www.ncbi.nlm.nih.gov/pubmed/35680900
Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes. Gunasekar SK, Xie L, Kumar A, Hong J, Chheda PR, Kang C, Kern DM, My-Ta C, Maurer J, Heebink J, Gerber EE, Grzesik WJ, Elliot-Hudson M, Zhang Y, Key P, Kulkarni CA, Beals JW, Smith GI, Samuel I, Smith JK, Nau P, Imai Y, Sheldon RD, Taylor EB, Lerner DJ, Norris AW, Klein S, Brohawn SG, Kerns R, Sah R Nature communications 35145074 Nat Commun 2022 Feb 10 https://www.ncbi.nlm.nih.gov/pubmed/35145074
Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A. Hoel CM, Zhang L, Brohawn SG eLife 36373655 Elife 2022 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/36373655
Ultrasound activates mechanosensitive TRAAK K(+) channels through the lipid membrane. Sorum B, Rietmeijer RA, Gopakumar K, Adesnik H, Brohawn SG Proceedings of the National Academy of Sciences of the United States of America 33542098 Proc Natl Acad Sci U S A 2021 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/33542098
Physical basis for distinct basal and mechanically gated activity of the human K(+) channel TRAAK. Rietmeijer RA, Sorum B, Li B, Brohawn SG Neuron 34390650 Neuron 2021 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/34390650
SARS-CoV-2 3a expression, purification, and reconstitution into lipid nanodiscs. Kern DM, Brohawn SG Methods in enzymology 34099172 Methods Enzymol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34099172
Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex. Wang JY, Hoel CM, Al-Shayeb B, Banfield JF, Brohawn SG, Doudna JA Nature communications 33958590 Nat Commun 2021 May 6 https://www.ncbi.nlm.nih.gov/pubmed/33958590
Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca(2+)-dependent switch from intra- to intermembrane dimerization. Li B, Hoel CM, Brohawn SG Nature communications 34824283 Nat Commun 2021 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/34824283
Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs. Tucker K, Sridharan S, Adesnik H, Brohawn SG Nature communications 35977941 Nat Commun 2022 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/35977941
Studying Mechanosensitivity of Two-Pore Domain K(+) Channels in Cellular and Reconstituted Proteoliposome Membranes. Del Mármol J, Rietmeijer RA, Brohawn SG Methods in molecular biology (Clifton, N.J.) 29058189 Methods Mol Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/29058189
Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs. Kern DM, Sorum B, Mali SS, Hoel CM, Sridharan S, Remis JP, Toso DB, Kotecha A, Bautista DM, Brohawn SG Nature structural & molecular biology 34158638 Nat Struct Mol Biol 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34158638
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The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. Brohawn SG, Wang W, Handler A, Campbell EB, Schwarz JR, MacKinnon R eLife 31674909 Elife 2019 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/31674909
Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs. Kern DM, Sorum B, Mali SS, Hoel CM, Sridharan S, Remis JP, Toso DB, Kotecha A, Bautista DM, Brohawn SG bioRxiv : the preprint server for biology 32587976 bioRxiv 2021 Jan 26 https://www.ncbi.nlm.nih.gov/pubmed/32587976
Structural basis for pH gating of the two-pore domain K(+) channel TASK2. Li B, Rietmeijer RA, Brohawn SG Nature 32999458 Nature 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32999458
Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs. Reid MS, Kern DM, Brohawn SG eLife 32286222 Elife 2020 Apr 14 https://www.ncbi.nlm.nih.gov/pubmed/32286222
Replication timing alterations in leukemia affect clinically relevant chromosome domains. Rivera-Mulia JC, Sasaki T, Trevilla-Garcia C, Nakamichi N, Knapp DJHF, Hammond CA, Chang BH, Tyner JW, Devidas M, Zimmerman J, Klein KN, Somasundaram V, Druker BJ, Gruber TA, Koren A, Eaves CJ, Gilbert DM Blood advances 31698451 Blood Adv 2019 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/31698451
Positive and Negative Regulation of DNA Replication Initiation. Ding Q, Koren A Trends in genetics : TIG 32739030 Trends Genet 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/32739030
Cancer Mutational Processes Vary in Their Association with Replication Timing and Chromatin Accessibility. Yaacov A, Vardi O, Blumenfeld B, Greenberg A, Massey DJ, Koren A, Adar S, Simon I, Rosenberg S Cancer research 34702725 Cancer Res 2021 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/34702725
Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. Caballero M, Ge T, Rebelo AR, Seo S, Kim S, Brooks K, Zuccaro M, Kanagaraj R, Vershkov D, Kim D, Smogorzewska A, Smolka M, Benvenisty N, West SC, Egli D, Mace EM, Koren A Human molecular genetics 35394024 Hum Mol Genet 2022 Aug 25 https://www.ncbi.nlm.nih.gov/pubmed/35394024
TIGER: inferring DNA replication timing from whole-genome sequence data. Koren A, Massey DJ, Bracci AN Bioinformatics (Oxford, England) 33704387 Bioinformatics 2021 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/33704387
Cell-type specificity of the human mutation landscape with respect to DNA replication dynamics. Caballero M, Boos D, Koren A Cell genomics 37388911 Cell Genom 2023 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/37388911
Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer. Webster ALH, Sanders MA, Patel K, Dietrich R, Noonan RJ, Lach FP, White RR, Goldfarb A, Hadi K, Edwards MM, Donovan FX, Hoogenboezem RM, Jung M, Sridhar S, Wiley TF, Fedrigo O, Tian H, Rosiene J, Heineman T, Kennedy JA, Bean L, Rosti RO, Tryon R, Gonzalez AM, Rosenberg A, Luo JD, Carroll TS, Shroff S, Beaumont M, Velleuer E, Rastatter JC, Wells SI, Surrallés J, Bagby G, MacMillan ML, Wagner JE, Cancio M, Boulad F, Scognamiglio T, Vaughan R, Beaumont KG, Koren A, Imielinski M, Chandrasekharappa SC, Auerbach AD, Singh B, Kutler DI, Campbell PJ, Smogorzewska A Nature 36450981 Nature 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36450981
Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication. Jones MJK, Gelot C, Munk S, Koren A, Kawasoe Y, George KA, Santos RE, Olsen JV, McCarroll SA, Frattini MG, Takahashi TS, Jallepalli PV Molecular cell 33545059 Mol Cell 2021 Feb 4 https://www.ncbi.nlm.nih.gov/pubmed/33545059
Mutation Rate Variability across Human Y-Chromosome Haplogroups. Ding Q, Hu Y, Koren A, Clark AG Molecular biology and evolution 33049047 Mol Biol Evol 2021 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/33049047
Germline DNA replication timing shapes mammalian genome composition. Yehuda Y, Blumenfeld B, Mayorek N, Makedonski K, Vardi O, Cohen-Daniel L, Mansour Y, Baror-Sebban S, Masika H, Farago M, Berger M, Carmi S, Buganim Y, Koren A, Simon I Nucleic acids research 29986092 Nucleic Acids Res 2018 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/29986092
Germline Structural Variations Are Preferential Sites of DNA Replication Timing Plasticity during Development. Hulke ML, Siefert JC, Sansam CL, Koren A Genome biology and evolution 31076752 Genome Biol Evol 2019 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/31076752
Genomic methods for measuring DNA replication dynamics. Hulke ML, Massey DJ, Koren A Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 31848781 Chromosome Res 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/31848781
The genetic architecture of DNA replication timing in human pluripotent stem cells. Ding Q, Edwards MM, Wang N, Zhu X, Bracci AN, Hulke ML, Hu Y, Tong Y, Hsiao J, Charvet CJ, Ghosh S, Handsaker RE, Eggan K, Merkle FT, Gerhardt J, Egli D, Clark AG, Koren A Nature communications 34799581 Nat Commun 2021 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/34799581
Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells. Deshpande M, Paniza T, Jalloul N, Nanjangud G, Twarowski J, Koren A, Zaninovic N, Zhan Q, Chadalavada K, Malkova A, Khiabanian H, Madireddy A, Rosenwaks Z, Gerhardt J Molecular cell 36099913 Mol Cell 2022 Oct 20 https://www.ncbi.nlm.nih.gov/pubmed/36099913
High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control. Massey DJ, Koren A Nature communications 35504890 Nat Commun 2022 May 3 https://www.ncbi.nlm.nih.gov/pubmed/35504890
Telomere-to-telomere human DNA replication timing profiles. Massey DJ, Koren A Scientific reports 35688856 Sci Rep 2022 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/35688856
Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes. Rivas MA, Durmaz C, Kloetgen A, Chin CR, Chen Z, Bhinder B, Koren A, Viny AD, Scharer CD, Boss JM, Elemento O, Mason CE, Melnick AM Frontiers in immunology 34621263 Front Immunol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34621263
Replication timing analysis in polyploid cells reveals Rif1 uses multiple mechanisms to promote underreplication in Drosophila. Das S, Caballero M, Kolesnikova T, Zhimulev I, Koren A, Nordman J Genetics 34740250 Genetics 2021 Nov 5 https://www.ncbi.nlm.nih.gov/pubmed/34740250
Next-Generation Sequencing Enables Spatiotemporal Resolution of Human Centromere Replication Timing. Massey DJ, Kim D, Brooks KE, Smolka MB, Koren A Genes 30987063 Genes (Basel) 2019 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/30987063
The landscape of somatic mutations in lymphoblastoid cell lines. Caballero M, Koren A Cell genomics 37388907 Cell Genom 2023 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/37388907
Assembly of a nucleus-like structure during viral replication in bacteria. Chaikeeratisak V, Nguyen K, Khanna K, Brilot AF, Erb ML, Coker JK, Vavilina A, Newton GL, Buschauer R, Pogliano K, Villa E, Agard DA, Pogliano J Science (New York, N.Y.) 28082593 Science 2017 Jan 13 https://www.ncbi.nlm.nih.gov/pubmed/28082593
The In Situ Structure of Parkinson's Disease-Linked LRRK2. Watanabe R, Buschauer R, Böhning J, Audagnotto M, Lasker K, Lu TW, Boassa D, Taylor S, Villa E Cell 32783917 Cell 2020 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/32783917
Shaping an Endospore: Architectural Transformations During Bacillus subtilis Sporulation. Khanna K, Lopez-Garrido J, Pogliano K Annual review of microbiology 32660383 Annu Rev Microbiol 2020 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/32660383
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Lu S, Ye Q, Singh D, Cao Y, Diedrich JK, Yates JR 3rd, Villa E, Cleveland DW, Corbett KD Nature communications 33479198 Nat Commun 2021 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/33479198
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. Yu H, Lu S, Gasior K, Singh D, Vazquez-Sanchez S, Tapia O, Toprani D, Beccari MS, Yates JR 3rd, Da Cruz S, Newby JM, Lafarga M, Gladfelter AS, Villa E, Cleveland DW Science (New York, N.Y.) 33335017 Science 2021 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/33335017
Challenges of Integrating Stochastic Dynamics and Cryo-Electron Tomograms in Whole-Cell Simulations. Earnest TM, Watanabe R, Stone JE, Mahamid J, Baumeister W, Villa E, Luthey-Schulten Z The journal of physical chemistry. B 28291359 J Phys Chem B 2017 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/28291359
The molecular architecture of engulfment during Bacillus subtilis sporulation. Khanna K, Lopez-Garrido J, Zhao Z, Watanabe R, Yuan Y, Sugie J, Pogliano K, Villa E eLife 31282858 Elife 2019 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/31282858
Viral Capsid Trafficking along Treadmilling Tubulin Filaments in Bacteria. Chaikeeratisak V, Khanna K, Nguyen KT, Sugie J, Egan ME, Erb ML, Vavilina A, Nonejuie P, Nieweglowska E, Pogliano K, Agard DA, Villa E, Pogliano J Cell 31199917 Cell 2019 Jun 13 https://www.ncbi.nlm.nih.gov/pubmed/31199917
Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography. Wagner FR, Watanabe R, Schampers R, Singh D, Persoon H, Schaffer M, Fruhstorfer P, Plitzko J, Villa E Nature protocols 32405053 Nat Protoc 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32405053
Chromosome Translocation Inflates Bacillus Forespores and Impacts Cellular Morphology. Lopez-Garrido J, Ojkic N, Khanna K, Wagner FR, Villa E, Endres RG, Pogliano K Cell 29425492 Cell 2018 Feb 8 https://www.ncbi.nlm.nih.gov/pubmed/29425492
Generating Chromosome Geometries in a Minimal Cell From Cryo-Electron Tomograms and Chromosome Conformation Capture Maps. Gilbert BR, Thornburg ZR, Lam V, Rashid FM, Glass JI, Villa E, Dame RT, Luthey-Schulten Z Frontiers in molecular biosciences 34368224 Front Mol Biosci 2021 https://www.ncbi.nlm.nih.gov/pubmed/34368224
Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Akey CW, Singh D, Ouch C, Echeverria I, Nudelman I, Varberg JM, Yu Z, Fang F, Shi Y, Wang J, Salzberg D, Song K, Xu C, Gumbart JC, Suslov S, Unruh J, Jaspersen SL, Chait BT, Sali A, Fernandez-Martinez J, Ludtke SJ, Villa E, Rout MP Cell 34982960 Cell 2022 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/34982960
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems. Lasker K, Boeynaems S, Lam V, Scholl D, Stainton E, Briner A, Jacquemyn M, Daelemans D, Deniz A, Villa E, Holehouse AS, Gitler AD, Shapiro L Nature communications 36163138 Nat Commun 2022 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/36163138
ExoSloNano: Multi-Modal Nanogold Tags for identification of Macromolecules in Live Cells & Cryo-Electron Tomograms. Young LN, Sherrard A, Zhou H, Shaikh F, Hutchings J, Riggi M, Rosen MK, Giraldez AJ, Villa E bioRxiv : the preprint server for biology 39416124 bioRxiv 2024 Oct 13 https://www.ncbi.nlm.nih.gov/pubmed/39416124
The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Lu S, Ye Q, Singh D, Villa E, Cleveland DW, Corbett KD bioRxiv : the preprint server for biology 32766587 bioRxiv 2020 Jul 31 https://www.ncbi.nlm.nih.gov/pubmed/32766587
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction. Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE Nature 32814344 Nature 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/32814344
Practical Approaches for Cryo-FIB Milling and Applications for Cellular Cryo-Electron Tomography. Lam V, Villa E Methods in molecular biology (Clifton, N.J.) 33367999 Methods Mol Biol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33367999
Entropy-regularized deconvolution of cellular cryotransmission electron tomograms. Croxford M, Elbaum M, Arigovindan M, Kam Z, Agard D, Villa E, Sedat J Proceedings of the National Academy of Sciences of the United States of America 34876518 Proc Natl Acad Sci U S A 2021 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/34876518
The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC). Rale MJ, Romer B, Mahon BP, Travis SM, Petry S eLife 36515268 Elife 2022 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/36515268
How TPX2 helps microtubules branch out. Alfaro-Aco R, Petry S Cell cycle (Georgetown, Tex.) 28767311 Cell Cycle 2017 https://www.ncbi.nlm.nih.gov/pubmed/28767311
Biochemical reconstitution of branching microtubule nucleation. Alfaro-Aco R, Thawani A, Petry S eLife 31933480 Elife 2020 Jan 14 https://www.ncbi.nlm.nih.gov/pubmed/31933480
Visualizing and Analyzing Branching Microtubule Nucleation Using Meiotic Xenopus Egg Extracts and TIRF Microscopy. King M, Petry S Methods in molecular biology (Clifton, N.J.) 27193844 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/27193844
Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules. Song JG, King MR, Zhang R, Kadzik RS, Thawani A, Petry S The Journal of cell biology 29875259 J Cell Biol 2018 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/29875259
Building the Microtubule Cytoskeleton Piece by Piece. Alfaro-Aco R, Petry S The Journal of biological chemistry 25957410 J Biol Chem 2015 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/25957410
The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy. Thawani A, Rale MJ, Coudray N, Bhabha G, Stone HA, Shaevitz JW, Petry S eLife 32538784 Elife 2020 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/32538784
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A hydrodynamic instability drives protein droplet formation on microtubules to nucleate branches. Setru SU, Gouveia B, Alfaro-Aco R, Shaevitz JW, Stone HA, Petry S Nature physics 35211183 Nat Phys 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/35211183
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Microtubule nucleation for spindle assembly: one molecule at a time. Kraus J, Alfaro-Aco R, Gouveia B, Petry S Trends in biochemical sciences 37482516 Trends Biochem Sci 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37482516
Confinement size determines the architecture of Ran-induced microtubule networks. Gai Y, Cook B, Setru S, Stone HA, Petry S Soft matter 34041514 Soft Matter 2021 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/34041514
Phase Transitioning the Centrosome into a Microtubule Nucleator. Rale MJ, Kadzik RS, Petry S Biochemistry 29256606 Biochemistry 2018 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/29256606
Mechanisms of Mitotic Spindle Assembly. Petry S Annual review of biochemistry 27145846 Annu Rev Biochem 2016 Jun 2 https://www.ncbi.nlm.nih.gov/pubmed/27145846
Spatiotemporal organization of branched microtubule networks. Thawani A, Stone HA, Shaevitz JW, Petry S eLife 31066674 Elife 2019 May 8 https://www.ncbi.nlm.nih.gov/pubmed/31066674
Acentrosomal spindles assemble from branching microtubule nucleation near chromosomes in Xenopus laevis egg extract. Gouveia B, Setru SU, King MR, Hamlin A, Stone HA, Shaevitz JW, Petry S Nature communications 37344488 Nat Commun 2023 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/37344488
Molecular insight into how γ-TuRC makes microtubules. Thawani A, Petry S Journal of cell science 34297125 J Cell Sci 2021 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/34297125
How Microtubules Build the Spindle Branch by Branch. Travis SM, Mahon BP, Petry S Annual review of cell and developmental biology 35759800 Annu Rev Cell Dev Biol 2022 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/35759800
Structural analysis of the role of TPX2 in branching microtubule nucleation. Alfaro-Aco R, Thawani A, Petry S The Journal of cell biology 28264915 J Cell Biol 2017 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/28264915
Dissecting Protein Complexes in Branching Microtubule Nucleation Using Meiotic Xenopus Egg Extracts. Song JG, Petry S Cold Spring Harbor protocols 29321281 Cold Spring Harb Protoc 2018 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/29321281
XMAP215 is a microtubule nucleation factor that functions synergistically with the γ-tubulin ring complex. Thawani A, Kadzik RS, Petry S Nature cell biology 29695792 Nat Cell Biol 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29695792
Selective binding of a toxin and phosphatidylinositides to a mammalian potassium channel. Liu Y, LoCaste CE, Liu W, Poltash ML, Russell DH, Laganowsky A Nature communications 30902995 Nat Commun 2019 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/30902995
Variable-Temperature ESI-IMS-MS Analysis of Myohemerythrin Reveals Ligand Losses, Unfolding, and a Non-Native Disulfide Bond. Woodall DW, El-Baba TJ, Fuller DR, Liu W, Brown CJ, Laganowsky A, Russell DH, Clemmer DE Analytical chemistry 31038926 Anal Chem 2019 May 21 https://www.ncbi.nlm.nih.gov/pubmed/31038926
Investigation of Protein-Lipid Interactions Using Native Mass Spectrometry. Cong X, Patrick JW, Liu Y, Liang X, Liu W, Laganowsky A Methods in molecular biology (Clifton, N.J.) 34718990 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/34718990
Small molecule peptidomimetic trypsin inhibitors: validation of an EKO binding mode, but with a twist. Lyu RL, Joy S, Packianathan C, Laganowsky A, Burgess K Organic & biomolecular chemistry 35225309 Org Biomol Chem 2022 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/35225309
Entropy in the Molecular Recognition of Membrane Protein-Lipid Interactions. Qiao P, Schrecke S, Walker T, McCabe JW, Lyu J, Zhu Y, Zhang T, Kumar S, Clemmer D, Russell DH, Laganowsky A The journal of physical chemistry letters 34928154 J Phys Chem Lett 2021 Dec 30 https://www.ncbi.nlm.nih.gov/pubmed/34928154
Development and Evaluation of a Reverse-Entry Ion Source Orbitrap Mass Spectrometer. Poltash ML, McCabe JW, Patrick JW, Laganowsky A, Russell DH Journal of the American Society for Mass Spectrometry 29796735 J Am Soc Mass Spectrom 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/29796735
First-Principles Collision Cross Section Measurements of Large Proteins and Protein Complexes. McCabe JW, Mallis CS, Kocurek KI, Poltash ML, Shirzadeh M, Hebert MJ, Fan L, Walker TE, Zheng X, Jiang T, Dong S, Lin CW, Laganowsky A, Russell DH Analytical chemistry 32662991 Anal Chem 2020 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/32662991
Implementing Digital-Waveform Technology for Extended m/z Range Operation on a Native Dual-Quadrupole FT-IM-Orbitrap Mass Spectrometer. McCabe JW, Jones BJ, Walker TE, Schrader RL, Huntley AP, Lyu J, Hoffman NM, Anderson GA, Reilly PTA, Laganowsky A, Wysocki VH, Russell DH Journal of the American Society for Mass Spectrometry 34797072 J Am Soc Mass Spectrom 2021 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/34797072
Allosteric modulation of protein-protein interactions by individual lipid binding events. Cong X, Liu Y, Liu W, Liang X, Laganowsky A Nature communications 29259178 Nat Commun 2017 Dec 19 https://www.ncbi.nlm.nih.gov/pubmed/29259178
THE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY-MASS SPECTROMETRY. McCabe JW, Hebert MJ, Shirzadeh M, Mallis CS, Denton JK, Walker TE, Russell DH Mass spectrometry reviews 32608033 Mass Spectrom Rev 2021 May https://www.ncbi.nlm.nih.gov/pubmed/32608033
A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins. Khan D, Lee D, Gulten G, Aggarwal A, Wofford J, Krieger I, Tripathi A, Patrick JW, Eckert DM, Laganowsky A, Sacchettini J, Lindahl P, Bankaitis VA eLife 32780017 Elife 2020 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/32780017
Development of Native MS Capabilities on an Extended Mass Range Q-TOF MS. Mallis CS, Zheng X, Qiu X, McCabe JW, Shirzadeh M, Lyu J, Laganowsky A, Russell DH International journal of mass spectrometry 33162786 Int J Mass Spectrom 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33162786
Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding. McCabe JW, Shirzadeh M, Walker TE, Lin CW, Jones BJ, Wysocki VH, Barondeau DP, Clemmer DE, Laganowsky A, Russell DH Analytical chemistry 33904705 Anal Chem 2021 May 11 https://www.ncbi.nlm.nih.gov/pubmed/33904705
Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants. Moghadamchargari Z, Shirzadeh M, Liu C, Schrecke S, Packianathan C, Russell DH, Zhao M, Laganowsky A Proceedings of the National Academy of Sciences of the United States of America 33723061 Proc Natl Acad Sci U S A 2021 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/33723061
Surface induced dissociation as a tool to study membrane protein complexes. Harvey SR, Liu Y, Liu W, Wysocki VH, Laganowsky A Chemical communications (Cambridge, England) 28243658 Chem Commun (Camb) 2017 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/28243658
Generation of Charge-Reduced Ions of Membrane Protein Complexes for Native Ion Mobility Mass Spectrometry Studies. Patrick JW, Laganowsky A Journal of the American Society for Mass Spectrometry 30887461 J Am Soc Mass Spectrom 2019 May https://www.ncbi.nlm.nih.gov/pubmed/30887461
Topological Analysis of Transthyretin Disassembly Mechanism: Surface-Induced Dissociation Reveals Hidden Reaction Pathways. Shirzadeh M, Boone CD, Laganowsky A, Russell DH Analytical chemistry 30642177 Anal Chem 2019 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/30642177
Evidence for Many Unique Solution Structures for Chymotrypsin Inhibitor 2: A Thermodynamic Perspective Derived from vT-ESI-IMS-MS Measurements. Raab SA, El-Baba TJ, Woodall DW, Liu W, Liu Y, Baird Z, Hales DA, Laganowsky A, Russell DH, Clemmer DE Journal of the American Chemical Society 32866376 J Am Chem Soc 2020 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/32866376
Allostery revealed within lipid binding events to membrane proteins. Patrick JW, Boone CD, Liu W, Conover GM, Liu Y, Cong X, Laganowsky A Proceedings of the National Academy of Sciences of the United States of America 29507234 Proc Natl Acad Sci U S A 2018 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/29507234
Protons Are Fast and Smart; Proteins Are Slow and Dumb: On the Relationship of Electrospray Ionization Charge States and Conformations. Raab SA, El-Baba TJ, Laganowsky A, Russell DH, Valentine SJ, Clemmer DE Journal of the American Society for Mass Spectrometry 34151568 J Am Soc Mass Spectrom 2021 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/34151568
Cupric Ions Selectively Modulate TRAAK-Phosphatidylserine Interactions. Zhu Y, Schrecke S, Tang S, Odenkirk MT, Walker T, Stover L, Lyu J, Zhang T, Russell D, Baker ES, Yan X, Laganowsky A Journal of the American Chemical Society 35421309 J Am Chem Soc 2022 Apr 27 https://www.ncbi.nlm.nih.gov/pubmed/35421309
Structural basis for lipid and copper regulation of the ABC transporter MsbA. Lyu J, Liu C, Zhang T, Schrecke S, Elam NP, Packianathan C, Hochberg GKA, Russell D, Zhao M, Laganowsky A Nature communications 36435815 Nat Commun 2022 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/36435815
Enhanced Characterization of Membrane Protein Complexes by Ultraviolet Photodissociation Mass Spectrometry. Sipe SN, Patrick JW, Laganowsky A, Brodbelt JS Analytical chemistry 31765130 Anal Chem 2020 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/31765130
Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1. Bergdoll LA, Lerch MT, Patrick JW, Belardo K, Altenbach C, Bisignano P, Laganowsky A, Grabe M, Hubbell WL, Abramson J Proceedings of the National Academy of Sciences of the United States of America 29279396 Proc Natl Acad Sci U S A 2018 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/29279396
Insight into the Phospholipid-Binding Preferences of Kir3.4. Qiao P, Schrecke S, Lyu J, Zhu Y, Zhang T, Benavides A, Laganowsky A Biochemistry 34846128 Biochemistry 2021 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/34846128
Selective regulation of human TRAAK channels by biologically active phospholipids. Schrecke S, Zhu Y, McCabe JW, Bartz M, Packianathan C, Zhao M, Zhou M, Russell D, Laganowsky A Nature chemical biology 32989299 Nat Chem Biol 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/32989299
Fourier Transform-Ion Mobility-Orbitrap Mass Spectrometer: A Next-Generation Instrument for Native Mass Spectrometry. Poltash ML, McCabe JW, Shirzadeh M, Laganowsky A, Clowers BH, Russell DH Analytical chemistry 30091588 Anal Chem 2018 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/30091588
Discovery of Potent Charge-Reducing Molecules for Native Ion Mobility Mass Spectrometry Studies. Lyu J, Liu Y, McCabe JW, Schrecke S, Fang L, Russell DH, Laganowsky A Analytical chemistry 32672445 Anal Chem 2020 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/32672445
Native IM-Orbitrap MS: Resolving What Was Hidden. Poltash ML, McCabe JW, Shirzadeh M, Laganowsky A, Russell DH Trends in analytical chemistry : TRAC 32189816 Trends Analyt Chem 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/32189816
Variable-Temperature Native Mass Spectrometry for Studies of Protein Folding, Stabilities, Assembly, and Molecular Interactions. Laganowsky A, Clemmer DE, Russell DH Annual review of biophysics 34932911 Annu Rev Biophys 2022 May 9 https://www.ncbi.nlm.nih.gov/pubmed/34932911
Intrinsic GTPase Activity of K-RAS Monitored by Native Mass Spectrometry. Moghadamchargari Z, Huddleston J, Shirzadeh M, Zheng X, Clemmer DE, M Raushel F, Russell DH, Laganowsky A Biochemistry 31306575 Biochemistry 2019 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/31306575
Double and triple thermodynamic mutant cycles reveal the basis for specific MsbA-lipid interactions. Lyu J, Zhang T, Marty MT, Clemmer D, Russell DH, Laganowsky A bioRxiv : the preprint server for biology 37461710 bioRxiv 2023 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/37461710
Double and triple thermodynamic mutant cycles reveal the basis for specific MsbA-lipid interactions. Lyu J, Zhang T, Marty MT, Clemmer D, Russell DH, Laganowsky A eLife 38252560 Elife 2024 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/38252560
Denoising genome-wide histone ChIP-seq with convolutional neural networks. Koh PW, Pierson E, Kundaje A Bioinformatics (Oxford, England) 28881977 Bioinformatics 2017 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/28881977
Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study. Wainberg M, Mahajan A, Kundaje A, McCarthy MI, Ingelsson E, Sinnott-Armstrong N, Rivas MA PLoS medicine 31821322 PLoS Med 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31821322
GenomeDISCO: a concordance score for chromosome conformation capture experiments using random walks on contact map graphs. Ursu O, Boley N, Taranova M, Wang YXR, Yardimci GG, Stafford Noble W, Kundaje A Bioinformatics (Oxford, England) 29554289 Bioinformatics 2018 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/29554289
Transcription-dependent domain-scale three-dimensional genome organization in the dinoflagellate Breviolum minutum. Marinov GK, Trevino AE, Xiang T, Kundaje A, Grossman AR, Greenleaf WJ Nature genetics 33927397 Nat Genet 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33927397
The chromatin landscape of the euryarchaeon Haloferax volcanii. Marinov GK, Bagdatli ST, Wu T, He C, Kundaje A, Greenleaf WJ Genome biology 37932847 Genome Biol 2023 Nov 6 https://www.ncbi.nlm.nih.gov/pubmed/37932847
Base-resolution models of transcription-factor binding reveal soft motif syntax. Avsec Ž, Weilert M, Shrikumar A, Krueger S, Alexandari A, Dalal K, Fropf R, McAnany C, Gagneur J, Kundaje A, Zeitlinger J Nature genetics 33603233 Nat Genet 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33603233
The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation. Kim DS, Risca VI, Reynolds DL, Chappell J, Rubin AJ, Jung N, Donohue LKH, Lopez-Pajares V, Kathiria A, Shi M, Zhao Z, Deep H, Sharmin M, Rao D, Lin S, Chang HY, Snyder MP, Greenleaf WJ, Kundaje A, Khavari PA Nature genetics 34650237 Nat Genet 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34650237
fastISM: performant in silico saturation mutagenesis for convolutional neural networks. Nair S, Shrikumar A, Schreiber J, Kundaje A Bioinformatics (Oxford, England) 35238376 Bioinformatics 2022 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/35238376
Transparency and reproducibility in artificial intelligence. Haibe-Kains B, Adam GA, Hosny A, Khodakarami F, Massive Analysis Quality Control (MAQC) Society Board of Directors, Waldron L, Wang B, McIntosh C, Goldenberg A, Kundaje A, Greene CS, Broderick T, Hoffman MM, Leek JT, Korthauer K, Huber W, Brazma A, Pineau J, Tibshirani R, Hastie T, Ioannidis JPA, Quackenbush J, Aerts HJWL Nature 33057217 Nature 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/33057217
Learning cis-regulatory principles of ADAR-based RNA editing from CRISPR-mediated mutagenesis. Liu X, Sun T, Shcherbina A, Li Q, Jarmoskaite I, Kappel K, Ramaswami G, Das R, Kundaje A, Li JB Nature communications 33846332 Nat Commun 2021 Apr 12 https://www.ncbi.nlm.nih.gov/pubmed/33846332
Deciphering regulatory DNA sequences and noncoding genetic variants using neural network models of massively parallel reporter assays. Movva R, Greenside P, Marinov GK, Nair S, Shrikumar A, Kundaje A PloS one 31206543 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/31206543
Discovering epistatic feature interactions from neural network models of regulatory DNA sequences. Greenside P, Shimko T, Fordyce P, Kundaje A Bioinformatics (Oxford, England) 30423062 Bioinformatics 2018 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/30423062
GkmExplain: fast and accurate interpretation of nonlinear gapped k-mer SVMs. Shrikumar A, Prakash E, Kundaje A Bioinformatics (Oxford, England) 31510661 Bioinformatics 2019 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/31510661
MTSplice predicts effects of genetic variants on tissue-specific splicing. Cheng J, Çelik MH, Kundaje A, Gagneur J Genome biology 33789710 Genome Biol 2021 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/33789710
Domain-adaptive neural networks improve cross-species prediction of transcription factor binding. Cochran K, Srivastava D, Shrikumar A, Balsubramani A, Hardison RC, Kundaje A, Mahony S Genome research 35042722 Genome Res 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35042722
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease. Ameen M, Sundaram L, Shen M, Banerjee A, Kundu S, Nair S, Shcherbina A, Gu M, Wilson KD, Varadarajan A, Vadgama N, Balsubramani A, Wu JC, Engreitz JM, Farh K, Karakikes I, Wang KC, Quertermous T, Greenleaf WJ, Kundaje A Cell 36563664 Cell 2022 Dec 22 https://www.ncbi.nlm.nih.gov/pubmed/36563664
Integrating regulatory DNA sequence and gene expression to predict genome-wide chromatin accessibility across cellular contexts. Nair S, Kim DS, Perricone J, Kundaje A Bioinformatics (Oxford, England) 31510655 Bioinformatics 2019 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/31510655
Accelerating in silico saturation mutagenesis using compressed sensing. Schreiber J, Nair S, Balsubramani A, Kundaje A Bioinformatics (Oxford, England) 35678521 Bioinformatics 2022 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/35678521
NETWORK MODELLING OF TOPOLOGICAL DOMAINS USING HI-C DATA. Wang YXR, Sarkar P, Ursu O, Kundaje A, Bickel PJ The annals of applied statistics 32968472 Ann Appl Stat 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/32968472
Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin. Yang D, Denny SK, Greenside PG, Chaikovsky AC, Brady JJ, Ouadah Y, Granja JM, Jahchan NS, Lim JS, Kwok S, Kong CS, Berghoff AS, Schmitt A, Reinhardt HC, Park KS, Preusser M, Kundaje A, Greenleaf WJ, Sage J, Winslow MM Cancer discovery 30228179 Cancer Discov 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30228179
Opportunities and challenges for transcriptome-wide association studies. Wainberg M, Sinnott-Armstrong N, Mancuso N, Barbeira AN, Knowles DA, Golan D, Ermel R, Ruusalepp A, Quertermous T, Hao K, Björkegren JLM, Im HK, Pasaniuc B, Rivas MA, Kundaje A Nature genetics 30926968 Nat Genet 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30926968
Brief Report: Cell Cycle Dynamics of Human Pluripotent Stem Cells Primed for Differentiation. Shcherbina A, Li J, Narayanan C, Greenleaf W, Kundaje A, Chetty S Stem cells (Dayton, Ohio) 31135093 Stem Cells 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31135093
The Kipoi repository accelerates community exchange and reuse of predictive models for genomics. Avsec Ž, Kreuzhuber R, Israeli J, Xu N, Cheng J, Shrikumar A, Banerjee A, Kim DS, Beier T, Urban L, Kundaje A, Stegle O, Gagneur J Nature biotechnology 31138913 Nat Biotechnol 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31138913
ChIP-ping the branches of the tree: functional genomics and the evolution of eukaryotic gene regulation. Marinov GK, Kundaje A Briefings in functional genomics 29529131 Brief Funct Genomics 2018 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/29529131
Opportunities and obstacles for deep learning in biology and medicine. Ching T, Himmelstein DS, Beaulieu-Jones BK, Kalinin AA, Do BT, Way GP, Ferrero E, Agapow PM, Zietz M, Hoffman MM, Xie W, Rosen GL, Lengerich BJ, Israeli J, Lanchantin J, Woloszynek S, Carpenter AE, Shrikumar A, Xu J, Cofer EM, Lavender CA, Turaga SC, Alexandari AM, Lu Z, Harris DJ, DeCaprio D, Qi Y, Kundaje A, Peng Y, Wiley LK, Segler MHS, Boca SM, Swamidass SJ, Huang A, Gitter A, Greene CS Journal of the Royal Society, Interface 29618526 J R Soc Interface 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29618526
Prediction of protein-ligand interactions from paired protein sequence motifs and ligand substructures. Greenside P, Hillenmeyer M, Kundaje A Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 29218866 Pac Symp Biocomput 2018 https://www.ncbi.nlm.nih.gov/pubmed/29218866
Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading. Kennedy DR, Lemiere J, Tan C, Simental E, Braxton J, Maxwell RA, Amine AA, Al-Sady B bioRxiv : the preprint server for biology 39554105 bioRxiv 2024 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/39554105
Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability. Greenstein RA, Barrales RR, Sanchez NA, Bisanz JE, Braun S, Al-Sady B Genes & development 31805521 Genes Dev 2020 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/31805521
Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability. Greenstein RA, Jones SK, Spivey EC, Rybarski JR, Finkelstein IJ, Al-Sady B eLife 30020075 Elife 2018 Jul 18 https://www.ncbi.nlm.nih.gov/pubmed/30020075
Epigenetic fates of gene silencing established by heterochromatin spreading in cell identity and genome stability. Greenstein RA, Al-Sady B Current genetics 30390097 Curr Genet 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30390097
Heterodimerization of H3K9 histone methyltransferases G9a and GLP activates methyl reading and writing capabilities. Sanchez NA, Kallweit LM, Trnka MJ, Clemmer CL, Al-Sady B The Journal of biological chemistry 34619147 J Biol Chem 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34619147
Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction. Greenstein RA, Ng H, Barrales RR, Tan C, Braun S, Al-Sady B PLoS genetics 35584134 PLoS Genet 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35584134
The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states. Murawska M, Greenstein RA, Schauer T, Olsen KCF, Ng H, Ladurner AG, Al-Sady B, Braun S Cell reports 34731638 Cell Rep 2021 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/34731638
The complete structure of the small-subunit processome. Barandun J, Chaker-Margot M, Hunziker M, Molloy KR, Chait BT, Klinge S Nature structural & molecular biology 28945246 Nat Struct Mol Biol 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28945246
Ribosome assembly coming into focus. Klinge S, Woolford JL Jr Nature reviews. Molecular cell biology 30467428 Nat Rev Mol Cell Biol 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30467428
Conformational switches control early maturation of the eukaryotic small ribosomal subunit. Hunziker M, Barandun J, Buzovetsky O, Steckler C, Molina H, Klinge S eLife 31206356 Elife 2019 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/31206356
Assembly and early maturation of large subunit precursors. Chaker-Margot M, Klinge S RNA (New York, N.Y.) 30670483 RNA 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30670483
Evolutionary compaction and adaptation visualized by the structure of the dormant microsporidian ribosome. Barandun J, Hunziker M, Vossbrinck CR, Klinge S Nature microbiology 31332387 Nat Microbiol 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31332387
Nucleolar maturation of the human small subunit processome. Singh S, Vanden Broeck A, Miller L, Chaker-Margot M, Klinge S Science (New York, N.Y.) 34516797 Science 2021 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/34516797
Assembly and structure of the SSU processome-a nucleolar precursor of the small ribosomal subunit. Barandun J, Hunziker M, Klinge S Current opinion in structural biology 29414516 Curr Opin Struct Biol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29414516
Modular assembly of the nucleolar pre-60S ribosomal subunit. Sanghai ZA, Miller L, Molloy KR, Barandun J, Hunziker M, Chaker-Margot M, Wang J, Chait BT, Klinge S Nature 29512650 Nature 2018 Apr 5 https://www.ncbi.nlm.nih.gov/pubmed/29512650
High Throughput Viability Assay for Microbiology. Meyer CT, Lynch GK, Stamo DF, Miller EJ, Chatterjee A, Kralj JM bioRxiv : the preprint server for biology 36712102 bioRxiv 2023 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/36712102
Machine Learning Establishes Single-Cell Calcium Dynamics as an Early Indicator of Antibiotic Response. Meyer CT, Jewell MP, Miller EJ, Kralj JM Microorganisms 34063175 Microorganisms 2021 May 5 https://www.ncbi.nlm.nih.gov/pubmed/34063175
Genome-Wide Functional Screen for Calcium Transients in Escherichia coli Identifies Increased Membrane Potential Adaptation to Persistent DNA Damage. Luder R, Bruni GN, Kralj JM Journal of bacteriology 33199283 J Bacteriol 2021 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/33199283
A high-throughput and low-waste viability assay for microbes. Meyer CT, Lynch GK, Stamo DF, Miller EJ, Chatterjee A, Kralj JM Nature microbiology 37919425 Nat Microbiol 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37919425
Live Cell Imaging Reveals pH Oscillations in Saccharomyces cerevisiae During Metabolic Transitions. Dodd BJT, Kralj JM Scientific reports 29066766 Sci Rep 2017 Oct 24 https://www.ncbi.nlm.nih.gov/pubmed/29066766
Finding the Spark. Kralj JM Bioelectricity 34476390 Bioelectricity 2021 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/34476390
Membrane voltage dysregulation driven by metabolic dysfunction underlies bactericidal activity of aminoglycosides. Bruni GN, Kralj JM eLife 32748785 Elife 2020 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/32748785
Voltage-gated calcium flux mediates Escherichia coli mechanosensation. Bruni GN, Weekley RA, Dodd BJT, Kralj JM Proceedings of the National Academy of Sciences of the United States of America 28808010 Proc Natl Acad Sci U S A 2017 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/28808010
High throughput sequencing of in vitro selections of mRNA-displayed peptides: data analysis and applications. Blanco C , Verbanic S , Seelig B , Chen IA Physical chemistry chemical physics : PCCP 31967131 Phys Chem Chem Phys 2020 Mar 28 https://www.ncbi.nlm.nih.gov/pubmed/31967131
Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages. Peng H, Borg RE, Dow LP, Pruitt BL, Chen IA Proceedings of the National Academy of Sciences of the United States of America 31932441 Proc Natl Acad Sci U S A 2020 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/31932441
Promiscuous Ribozymes and Their Proposed Role in Prebiotic Evolution. Janzen E, Blanco C, Peng H, Kenchel J, Chen IA Chemical reviews 32011135 Chem Rev 2020 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/32011135
Phage engineering and the evolutionary arms race. Peng H, Chen IA Current opinion in biotechnology 33113495 Curr Opin Biotechnol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33113495
Improved single-swab sample preparation for recovering bacterial and phage DNA from human skin and wound microbiomes. Verbanic S, Kim CY, Deacon JM, Chen IA BMC microbiology 31488062 BMC Microbiol 2019 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/31488062
Chimeric Phage Nanoparticles for Rapid Characterization of Bacterial Pathogens: Detection in Complex Biological Samples and Determination of Antibiotic Sensitivity. Peng H, Borg RE, Nguyen ABN, Chen IA ACS sensors 32314570 ACS Sens 2020 May 22 https://www.ncbi.nlm.nih.gov/pubmed/32314570
Kinetic sequencing (k-Seq) as a massively parallel assay for ribozyme kinetics: utility and critical parameters. Shen Y, Pressman A, Janzen E, Chen IA Nucleic acids research 33772580 Nucleic Acids Res 2021 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/33772580
PacBio sequencing output increased through uniform and directional fivefold concatenation. Kanwar N, Blanco C, Chen IA, Seelig B Scientific reports 34508117 Sci Rep 2021 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/34508117
Rapid Colorimetric Detection of Bacterial Species through the Capture of Gold Nanoparticles by Chimeric Phages. Peng H, Chen IA ACS nano 30586498 ACS Nano 2019 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/30586498
Genetically engineered filamentous phage for bacterial detection using magnetic resonance imaging. Borg RE, Ozbakir HF, Xu B, Li E, Fang X, Peng H, Chen IA, Mukherjee A Sensors & diagnostics 38405385 Sens Diagn 2023 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/38405385
Phage therapy administered noninvasively could be effective in thin tubes subject to episodic flow despite washout: a simulation study. Blanco C, Chen IA Physical biology 31266001 Phys Biol 2019 Jul 22 https://www.ncbi.nlm.nih.gov/pubmed/31266001
Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds. Verbanic S, Shen Y, Lee J, Deacon JM, Chen IA NPJ biofilms and microbiomes 32358500 NPJ Biofilms Microbiomes 2020 May 1 https://www.ncbi.nlm.nih.gov/pubmed/32358500
Treatment of Wound Infections in a Mouse Model Using Zn(2+)-Releasing Phage Bound to Gold Nanorods. Peng H, Rossetto D, Mansy SS, Jordan MC, Roos KP, Chen IA ACS nano 35239330 ACS Nano 2022 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/35239330
Emergent properties as by-products of prebiotic evolution of aminoacylation ribozymes. Janzen E, Shen Y, Vázquez-Salazar A, Liu Z, Blanco C, Kenchel J, Chen IA Nature communications 35752631 Nat Commun 2022 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/35752631
Modulation of α-Synuclein Aggregation In Vitro by a DNA Aptamer. Tran CH, Saha R, Blanco C, Bagchi D, Chen IA Biochemistry 35994742 Biochemistry 2022 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/35994742
Preparation of Bioconjugates of Chimeric M13 Phage and Gold Nanorods. Peng H, Chen IA Methods in molecular biology (Clifton, N.J.) 38526728 Methods Mol Biol 2024 https://www.ncbi.nlm.nih.gov/pubmed/38526728
The Chronic Wound Phageome: Phage Diversity and Associations with Wounds and Healing Outcomes. Verbanic S, Deacon JM, Chen IA Microbiology spectrum 35435739 Microbiol Spectr 2022 Jun 29 https://www.ncbi.nlm.nih.gov/pubmed/35435739
EasyDIVER: A Pipeline for Assembling and Counting High-Throughput Sequencing Data from In Vitro Evolution of Nucleic Acids or Peptides. Blanco C, Verbanic S, Seelig B, Chen IA Journal of molecular evolution 32529275 J Mol Evol 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32529275
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Lineage tracing and analog recording in mammalian cells by single-site DNA writing. Loveless TB, Grotts JH, Schechter MW, Forouzmand E, Carlson CK, Agahi BS, Liang G, Ficht M, Liu B, Xie X, Liu CC Nature chemical biology 33753928 Nat Chem Biol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33753928
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Evolving Small-Molecule Biosensors with Improved Performance and Reprogrammed Ligand Preference Using OrthoRep. Javanpour AA, Liu CC ACS synthetic biology 34597502 ACS Synth Biol 2021 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/34597502
Synthetic Epigenetics To Engineer Regulation. Loveless TB, Liu CC Biochemistry 30860818 Biochemistry 2019 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/30860818
Open-ended molecular recording of sequential cellular events into DNA. Loveless TB, Carlson CK, Dentzel Helmy CA, Hu VJ, Ross SK, Demelo MC, Murtaza A, Liang G, Ficht M, Singhai A, Pajoh-Casco MJ, Liu CC Nature chemical biology 39543397 Nat Chem Biol 2025 Apr https://www.ncbi.nlm.nih.gov/pubmed/39543397
Rapid generation of potent antibodies by autonomous hypermutation in yeast. Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC bioRxiv : the preprint server for biology 33200136 bioRxiv 2020 Nov 11 https://www.ncbi.nlm.nih.gov/pubmed/33200136
Tunable Expression Systems for Orthogonal DNA Replication. Zhong Z, Ravikumar A, Liu CC ACS synthetic biology 30408954 ACS Synth Biol 2018 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/30408954
Genetic Compatibility and Extensibility of Orthogonal Replication. Javanpour AA, Liu CC ACS synthetic biology 31095905 ACS Synth Biol 2019 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/31095905
Toward an orthogonal central dogma. Liu CC, Jewett MC, Chin JW, Voigt CA Nature chemical biology 29337969 Nat Chem Biol 2018 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/29337969
Mutually Orthogonal DNA Replication Systems In Vivo. Arzumanyan GA, Gabriel KN, Ravikumar A, Javanpour AA, Liu CC ACS synthetic biology 29969238 ACS Synth Biol 2018 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/29969238
Probing pathways of adaptation with continuous evolution. Zhong Z, Liu CC Current opinion in systems biology 31608311 Curr Opin Syst Biol 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/31608311
Automated Continuous Evolution of Proteins in Vivo. Zhong Z, Wong BG, Ravikumar A, Arzumanyan GA, Khalil AS, Liu CC ACS synthetic biology 32374988 ACS Synth Biol 2020 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/32374988
Rapid generation of potent antibodies by autonomous hypermutation in yeast. Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC Nature chemical biology 34168368 Nat Chem Biol 2021 Oct https://www.ncbi.nlm.nih.gov/pubmed/34168368
Genetic Engineering by DNA Recombineering. Papa LJ 3rd, Shoulders MD Current protocols in chemical biology 31483098 Curr Protoc Chem Biol 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31483098
Multidimensional chemical control of CRISPR-Cas9. Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A Nature chemical biology 27820801 Nat Chem Biol 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27820801
HSF1 Activation Can Restrict HIV Replication. Nekongo EE, Ponomarenko AI, Dewal MB, Butty VL, Browne EP, Shoulders MD ACS infectious diseases 32502335 ACS Infect Dis 2020 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/32502335
A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo. Moore CL, Papa LJ 3rd, Shoulders MD Journal of the American Chemical Society 29991261 J Am Chem Soc 2018 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/29991261
The Path of Least Resistance: Mechanisms to Reduce Influenza's Sensitivity to Oseltamivir. Phillips AM, Shoulders MD Journal of molecular biology 26748011 J Mol Biol 2016 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/26748011
Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin. Phillips AM, Doud MB, Gonzalez LO, Butty VL, Lin YS, Bloom JD, Shoulders MD eLife 30188321 Elife 2018 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/30188321
Transportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1. Moore CL, Dewal MB, Nekongo EE, Santiago S, Lu NB, Levine SS, Shoulders MD ACS chemical biology 26502114 ACS Chem Biol 2016 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/26502114
Host proteostasis modulates influenza evolution. Phillips AM, Gonzalez LO, Nekongo EE, Ponomarenko AI, McHugh SM, Butty VL, Levine SS, Lin YS, Mirny LA, Shoulders MD eLife 28949290 Elife 2017 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/28949290
Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones. Phillips AM, Ponomarenko AI, Chen K, Ashenberg O, Miao J, McHugh SM, Butty VL, Whittaker CA, Moore CL, Bloom JD, Lin YS, Shoulders MD PLoS biology 30222731 PLoS Biol 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30222731
An Adaptable Platform for Directed Evolution in Human Cells. Berman CM, Papa LJ 3rd, Hendel SJ, Moore CL, Suen PH, Weickhardt AF, Doan ND, Kumar CM, Uil TG, Butty VL, Hoeben RC, Shoulders MD Journal of the American Chemical Society 30427676 J Am Chem Soc 2018 Dec 26 https://www.ncbi.nlm.nih.gov/pubmed/30427676
Chemical Biology Framework to Illuminate Proteostasis. Sebastian RM, Shoulders MD Annual review of biochemistry 32097570 Annu Rev Biochem 2020 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/32097570
A common bacterial metabolite elicits prion-based bypass of glucose repression. Garcia DM, Dietrich D, Clardy J, Jarosz DF eLife 27906649 Elife 2016 Nov 29 https://www.ncbi.nlm.nih.gov/pubmed/27906649
A prion accelerates proliferation at the expense of lifespan. Garcia DM, Campbell EA, Jakobson CM, Tsuchiya M, Shaw EA, DiNardo AL, Kaeberlein M, Jarosz DF eLife 34545808 Elife 2021 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/34545808
Biomolecular Condensation: A New Phase in Cancer Research. Chakravarty AK, McGrail DJ, Lozanoski TM, Dunn BS, Shih DJH, Cirillo KM, Cetinkaya SH, Zheng WJ, Mills GB, Yi SS, Jarosz DF, Sahni N Cancer discovery 35852417 Cancer Discov 2022 Sep 2 https://www.ncbi.nlm.nih.gov/pubmed/35852417
Massively parallel experimental interrogation of natural variants in ancient signaling pathways reveals both purifying selection and local adaptation. Aguilar-Rodríguez J, Vila J, Chen SA, Razo-Mejia M, Ghosh O, Fraser HB, Jarosz DF, Petrov DA bioRxiv : the preprint server for biology 39553990 bioRxiv 2024 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/39553990
Organizing biochemistry in space and time using prion-like self-assembly. Jakobson CM, Jarosz DF Current opinion in systems biology 29725624 Curr Opin Syst Biol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29725624
A Prion Epigenetic Switch Establishes an Active Chromatin State. Harvey ZH, Chakravarty AK, Futia RA, Jarosz DF Cell 32109413 Cell 2020 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/32109413
A Non-amyloid Prion Particle that Activates a Heritable Gene Expression Program. Chakravarty AK, Smejkal T, Itakura AK, Garcia DM, Jarosz DF Molecular cell 31757755 Mol Cell 2020 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/31757755
What Has a Century of Quantitative Genetics Taught Us About Nature's Genetic Tool Kit? Jakobson CM, Jarosz DF Annual review of genetics 32897739 Annu Rev Genet 2020 Nov 23 https://www.ncbi.nlm.nih.gov/pubmed/32897739
Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome. She R, Chakravarty AK, Layton CJ, Chircus LM, Andreasson JO, Damaraju N, McMahon PL, Buenrostro JD, Jarosz DF, Greenleaf WJ Proceedings of the National Academy of Sciences of the United States of America 28325876 Proc Natl Acad Sci U S A 2017 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/28325876
Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits. Chakrabortee S, Byers JS, Jones S, Garcia DM, Bhullar B, Chang A, She R, Lee L, Fremin B, Lindquist S, Jarosz DF Cell 27693355 Cell 2016 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/27693355
Tissue-specific landscape of protein aggregation and quality control in an aging vertebrate. Chen YR, Harel I, Singh PP, Ziv I, Moses E, Goshtchevsky U, Machado BE, Brunet A, Jarosz DF Developmental cell 38810654 Dev Cell 2024 Jul 22 https://www.ncbi.nlm.nih.gov/pubmed/38810654
The Hsp90 Molecular Chaperone as a Global Modifier of the Genotype-Phenotype-Fitness Map: An Evolutionary Perspective. Aguilar-Rodríguez J, Jakobson CM, Jarosz DF Journal of molecular biology 39481633 J Mol Biol 2024 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/39481633
A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects. Jakobson CM, Hartl J, Trébulle P, Mülleder M, Jarosz DF, Ralser M bioRxiv : the preprint server for biology 39484408 bioRxiv 2024 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/39484408
Protein self-assembly: A new frontier in cell signaling. Saad S, Jarosz DF Current opinion in cell biology 33493989 Curr Opin Cell Biol 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33493989
The Hunt for Ancient Prions: Archaeal Prion-Like Domains Form Amyloid-Based Epigenetic Elements. Zajkowski T, Lee MD, Mondal SS, Carbajal A, Dec R, Brennock PD, Piast RW, Snyder JE, Bense NB, Dzwolak W, Jarosz DF, Rothschild LJ Molecular biology and evolution 33480998 Mol Biol Evol 2021 May 4 https://www.ncbi.nlm.nih.gov/pubmed/33480998
Molecular Origins of Complex Heritability in Natural Genotype-to-Phenotype Relationships. Jakobson CM, Jarosz DF Cell systems 31054809 Cell Syst 2019 May 22 https://www.ncbi.nlm.nih.gov/pubmed/31054809
Pervasive function and evidence for selection across standing genetic variation in S. cerevisiae. Jakobson CM, She R, Jarosz DF Nature communications 30874558 Nat Commun 2019 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/30874558
It Pays To Be in Phase. Itakura AK, Futia RA, Jarosz DF Biochemistry 29509425 Biochemistry 2018 May 1 https://www.ncbi.nlm.nih.gov/pubmed/29509425
Mapping Causal Variants with Single-Nucleotide Resolution Reveals Biochemical Drivers of Phenotypic Change. She R, Jarosz DF Cell 29373829 Cell 2018 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/29373829
Protein-Based Inheritance: Epigenetics beyond the Chromosome. Harvey ZH, Chen Y, Jarosz DF Molecular cell 29153393 Mol Cell 2018 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/29153393
Widespread Prion-Based Control of Growth and Differentiation Strategies in Saccharomyces cerevisiae. Itakura AK, Chakravarty AK, Jakobson CM, Jarosz DF Molecular cell 31757756 Mol Cell 2020 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/31757756
Hsp90 shapes adaptation by controlling the fitness consequences of regulatory variation. Jakobson CM, Aguilar-Rodríguez J, Jarosz DF bioRxiv : the preprint server for biology 37961536 bioRxiv 2023 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/37961536
Mutations, protein homeostasis, and epigenetic control of genome integrity. Xie JL, Jarosz DF DNA repair 30181040 DNA Repair (Amst) 2018 Nov https://www.ncbi.nlm.nih.gov/pubmed/30181040
High-throughput Screening for Protein-based Inheritance in S. cerevisiae. Byers JS, Jarosz DF Journal of visualized experiments : JoVE 28809826 J Vis Exp 2017 Aug 8 https://www.ncbi.nlm.nih.gov/pubmed/28809826
Protein aggregation and the evolution of stress resistance in clinical yeast. Chen YR, Ziv I, Swaminathan K, Elias JE, Jarosz DF Philosophical transactions of the Royal Society of London. Series B, Biological sciences 33866806 Philos Trans R Soc Lond B Biol Sci 2021 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/33866806
More than Just a Phase: Prions at the Crossroads of Epigenetic Inheritance and Evolutionary Change. Chakravarty AK, Jarosz DF Journal of molecular biology 30031007 J Mol Biol 2018 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/30031007
A CRISPR Approach to Neurodegenerative Diseases. Kampmann M Trends in molecular medicine 28478951 Trends Mol Med 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28478951
LRP1 is a master regulator of tau uptake and spread. Rauch JN, Luna G, Guzman E, Audouard M, Challis C, Sibih YE, Leshuk C, Hernandez I, Wegmann S, Hyman BT, Gradinaru V, Kampmann M, Kosik KS Nature 32296178 Nature 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32296178
Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation. Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M The Journal of biological chemistry 31578281 J Biol Chem 2019 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/31578281
Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance. Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, Ary BE, Bauer DP, Bergman ID, Brunetti RM, Chio CM, Dai SA, Dickinson MS, Elledge SK, Helsell CVM, Hendel NL, Kang E, Kern N, Khoroshkin MS, Kirkemo LL, Lewis GR, Lou K, Marin WM, Maxwell AM, McTigue PF, Myers-Turnbull D, Nagy TL, Natale AM, Oltion K, Pourmal S, Reder GK, Rettko NJ, Rohweder PJ, Schwarz DMC, Tan SK, Thomas PV, Tibble RW, Town JP, Tsai MK, Ugur FS, Wassarman DR, Wolff AM, Wu TS, Bogdanoff D, Li J, Thorn KS, O'Conchúir S, Swaney DL, Chow ED, Madhani HD, Redding S, Bolon DN, Kortemme T, DeRisi JL, Kampmann M, Fraser JS Biology open 30037883 Biol Open 2018 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/30037883
An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes. Oltion K, Carelli JD, Yang T, See SK, Wang HY, Kampmann M, Taunton J Cell 36638793 Cell 2023 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/36638793
Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability. Abrams J, Arhar T, Mok SA, Taylor IR, Kampmann M, Gestwicki JE Cell stress & chaperones 33547632 Cell Stress Chaperones 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33547632
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states. Dräger NM, Sattler SM, Huang CT, Teter OM, Leng K, Hashemi SH, Hong J, Aviles G, Clelland CD, Zhan L, Udeochu JC, Kodama L, Singleton AB, Nalls MA, Ichida J, Ward ME, Faghri F, Gan L, Kampmann M Nature neuroscience 35953545 Nat Neurosci 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35953545
Dual gene activation and knockout screen reveals directional dependencies in genetic networks. Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT Nature biotechnology 29334369 Nat Biotechnol 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29334369
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity. Zhang YJ, Guo L, Gonzales PK, Gendron TF, Wu Y, Jansen-West K, O'Raw AD, Pickles SR, Prudencio M, Carlomagno Y, Gachechiladze MA, Ludwig C, Tian R, Chew J, DeTure M, Lin WL, Tong J, Daughrity LM, Yue M, Song Y, Andersen JW, Castanedes-Casey M, Kurti A, Datta A, Antognetti G, McCampbell A, Rademakers R, Oskarsson B, Dickson DW, Kampmann M, Ward ME, Fryer JD, Link CD, Shorter J, Petrucelli L Science (New York, N.Y.) 30765536 Science 2019 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/30765536
A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure. Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K PLoS biology 30148842 PLoS Biol 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/30148842
NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems. Biebl MM, Delhommel F, Faust O, Zak KM, Agam G, Guo X, Mühlhofer M, Dahiya V, Hillebrand D, Popowicz GM, Kampmann M, Lamb DC, Rosenzweig R, Sattler M, Buchner J Molecular cell 35063133 Mol Cell 2022 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/35063133
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS Cell 33838111 Cell 2021 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/33838111
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine. Kampmann M ACS chemical biology 29035510 ACS Chem Biol 2018 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/29035510
Mapping the Genetic Landscape of Human Cells. Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA Cell 30033366 Cell 2018 Aug 9 https://www.ncbi.nlm.nih.gov/pubmed/30033366
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ Cell 30053424 Cell 2018 Jul 26 https://www.ncbi.nlm.nih.gov/pubmed/30053424
Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs). Rauch JN, Chen JJ, Sorum AW, Miller GM, Sharf T, See SK, Hsieh-Wilson LC, Kampmann M, Kosik KS Scientific reports 29686391 Sci Rep 2018 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/29686391
Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells. Kampmann M Chemical communications (Cambridge, England) 28487920 Chem Commun (Camb) 2017 Jun 29 https://www.ncbi.nlm.nih.gov/pubmed/28487920
A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling. Semesta KM, Tian R, Kampmann M, von Zastrow M, Tsvetanova NG PLoS genetics 33052901 PLoS Genet 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/33052901
Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes. Kanfer G, Sarraf SA, Maman Y, Baldwin H, Dominguez-Martin E, Johnson KR, Ward ME, Kampmann M, Lippincott-Schwartz J, Youle RJ The Journal of cell biology 33464298 J Cell Biol 2021 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/33464298
CRISPulator: a discrete simulation tool for pooled genetic screens. Nagy T, Kampmann M BMC bioinformatics 28732459 BMC Bioinformatics 2017 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/28732459
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS eLife 27661255 Elife 2016 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/27661255
The mTOR Complex Controls HIV Latency. Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E Cell host & microbe 27978436 Cell Host Microbe 2016 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/27978436
CRISPR-based functional genomics for neurological disease. Kampmann M Nature reviews. Neurology 32641861 Nat Rev Neurol 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32641861
Defining the ATPome reveals cross-optimization of metabolic pathways. Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K Nature communications 32859923 Nat Commun 2020 Aug 28 https://www.ncbi.nlm.nih.gov/pubmed/32859923
Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding. Newberry RW, Arhar T, Costello J, Hartoularos GC, Maxwell AM, Naing ZZC, Pittman M, Reddy NR, Schwarz DMC, Wassarman DR, Wu TS, Barrero D, Caggiano C, Catching A, Cavazos TB, Estes LS, Faust B, Fink EA, Goldman MA, Gomez YK, Gordon MG, Gunsalus LM, Hoppe N, Jaime-Garza M, Johnson MC, Jones MG, Kung AF, Lopez KE, Lumpe J, Martyn C, McCarthy EE, Miller-Vedam LE, Navarro EJ, Palar A, Pellegrino J, Saylor W, Stephens CA, Strickland J, Torosyan H, Wankowicz SA, Wong DR, Wong G, Redding S, Chow ED, DeGrado WF, Kampmann M ACS chemical biology 32786289 ACS Chem Biol 2020 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/32786289
CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons. Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M Neuron 31422865 Neuron 2019 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/31422865
Global Proteome Remodeling during ER Stress Involves Hac1-Driven Expression of Long Undecoded Transcript Isoforms. Van Dalfsen KM, Hodapp S, Keskin A, Otto GM, Berdan CA, Higdon A, Cheunkarndee T, Nomura DK, Jovanovic M, Brar GA Developmental cell 30016623 Dev Cell 2018 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/30016623
Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast. Eisenberg AR, Higdon AL, Hollerer I, Fields AP, Jungreis I, Diamond PD, Kellis M, Jovanovic M, Brar GA Cell systems 32710835 Cell Syst 2020 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/32710835
Global mapping of translation initiation sites by TIS profiling in budding yeast. Hollerer I, Powers EN, Brar GA STAR protocols 33458709 STAR Protoc 2021 Mar 19 https://www.ncbi.nlm.nih.gov/pubmed/33458709
Pervasive, Coordinated Protein-Level Changes Driven by Transcript Isoform Switching during Meiosis. Cheng Z, Otto GM, Powers EN, Keskin A, Mertins P, Carr SA, Jovanovic M, Brar GA Cell 29474919 Cell 2018 Feb 22 https://www.ncbi.nlm.nih.gov/pubmed/29474919
Precise Post-translational Tuning Occurs for Most Protein Complex Components during Meiosis. Eisenberg AR, Higdon A, Keskin A, Hodapp S, Jovanovic M, Brar GA Cell reports 30590036 Cell Rep 2018 Dec 26 https://www.ncbi.nlm.nih.gov/pubmed/30590036
Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate. Cheng Z, Mugler CF, Keskin A, Hodapp S, Chan LY, Weis K, Mertins P, Regev A, Jovanovic M, Brar GA Molecular cell 30503772 Mol Cell 2019 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/30503772
Tunable Transcriptional Interference at the Endogenous Alcohol Dehydrogenase Gene Locus in Drosophila melanogaster. Jorgensen V, Chen J, Vander Wende H, Harris DE, McCarthy A, Breznak S, Wong-Deyrup SW, Chen Y, Rangan P, Brar GA, Sawyer EM, Chan LY, Ünal E G3 (Bethesda, Md.) 32213532 G3 (Bethesda) 2020 May 4 https://www.ncbi.nlm.nih.gov/pubmed/32213532
Strategies and Challenges in Identifying Function for Thousands of sORF-Encoded Peptides in Meiosis. Hollerer I, Higdon A, Brar GA Proteomics 28929627 Proteomics 2018 May https://www.ncbi.nlm.nih.gov/pubmed/28929627
Beyond the Triplet Code: Context Cues Transform Translation. Brar GA Cell 27984720 Cell 2016 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/27984720
Global translation inhibition yields condition-dependent de-repression of ribosome biogenesis mRNAs. Cheng Z, Brar GA Nucleic acids research 30937450 Nucleic Acids Res 2019 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/30937450
Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells. Hollerer I, Barker JC, Jorgensen V, Tresenrider A, Dugast-Darzacq C, Chan LY, Darzacq X, Tjian R, Ünal E, Brar GA G3 (Bethesda, Md.) 30723103 G3 (Bethesda) 2019 Apr 9 https://www.ncbi.nlm.nih.gov/pubmed/30723103
The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S eLife 31612858 Elife 2019 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/31612858
A Spatial Interactome Reveals the Protein Organization of the Algal CO(2)-Concentrating Mechanism. Mackinder LCM, Chen C, Leib RD, Patena W, Blum SR, Rodman M, Ramundo S, Adams CM, Jonikas MC Cell 28938113 Cell 2017 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/28938113
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Dynamic Nuclear Polarization Nuclear Magnetic Resonance in Human Cells Using Fluorescent Polarizing Agents. Albert BJ, Gao C, Sesti EL, Saliba EP, Alaniva N, Scott FJ, Sigurdsson ST, Barnes AB Biochemistry 29924582 Biochemistry 2018 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/29924582
Instrumentation for cryogenic magic angle spinning dynamic nuclear polarization using 90L of liquid nitrogen per day. Albert BJ, Pahng SH, Alaniva N, Sesti EL, Rand PW, Saliba EP, Scott FJ, Choi EJ, Barnes AB Journal of magnetic resonance (San Diego, Calif. : 1997) 28888182 J Magn Reson 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28888182
Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation. Albert BJ, Niu A, Ramani R, Marshall GR, Wender PA, Williams RM, Ratner L, Barnes AB, Kyei GB Scientific reports 28785069 Sci Rep 2017 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/28785069
Pulsed Electron Decoupling and Strategies for Time Domain Dynamic Nuclear Polarization with Magic Angle Spinning. Saliba EP, Sesti EL, Alaniva N, Barnes AB The journal of physical chemistry letters 30180584 J Phys Chem Lett 2018 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/30180584
Fast electron paramagnetic resonance magic angle spinning simulations using analytical powder averaging techniques. Saliba EP, Barnes AB The Journal of chemical physics 31542017 J Chem Phys 2019 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/31542017
Frequency swept microwaves for hyperfine decoupling and time domain dynamic nuclear polarization. Hoff DE, Albert BJ, Saliba EP, Scott FJ, Choi EJ, Mardini M, Barnes AB Solid state nuclear magnetic resonance 26482131 Solid State Nucl Magn Reson 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26482131
Frequency-agile gyrotron for electron decoupling and pulsed dynamic nuclear polarization. Scott FJ, Saliba EP, Albert BJ, Alaniva N, Sesti EL, Gao C, Golota NC, Choi EJ, Jagtap AP, Wittmann JJ, Eckardt M, Harneit W, Corzilius B, Th Sigurdsson S, Barnes AB Journal of magnetic resonance (San Diego, Calif. : 1997) 29471275 J Magn Reson 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29471275
A versatile custom cryostat for dynamic nuclear polarization supports multiple cryogenic magic angle spinning transmission line probes. Scott FJ, Alaniva N, Golota NC, Sesti EL, Saliba EP, Price LE, Albert BJ, Chen P, O'Connor RD, Barnes AB Journal of magnetic resonance (San Diego, Calif. : 1997) 30342370 J Magn Reson 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30342370
Magic angle spinning NMR with metallized rotors as cylindrical microwave resonators. Scott FJ, Sesti EL, Choi EJ, Laut AJ, Sirigiri JR, Barnes AB Magnetic resonance in chemistry : MRC 29672916 Magn Reson Chem 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/29672916
Magic angle spinning NMR below 6 K with a computational fluid dynamics analysis of fluid flow and temperature gradients. Sesti EL, Alaniva N, Rand PW, Choi EJ, Albert BJ, Saliba EP, Scott FJ, Barnes AB Journal of magnetic resonance (San Diego, Calif. : 1997) 29161649 J Magn Reson 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29161649
Frequency-chirped dynamic nuclear polarization with magic angle spinning using a frequency-agile gyrotron. Gao C, Alaniva N, Saliba EP, Sesti EL, Judge PT, Scott FJ, Halbritter T, Sigurdsson ST, Barnes AB Journal of magnetic resonance (San Diego, Calif. : 1997) 31525550 J Magn Reson 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31525550
T-REX on-demand redox targeting in live cells. Parvez S, Long MJ, Lin HY, Zhao Y, Haegele JA, Pham VN, Lee DK, Aye Y Nature protocols 27809314 Nat Protoc 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27809314
On-Demand Targeting: Investigating Biology with Proximity-Directed Chemistry. Long MJ, Poganik JR, Aye Y Journal of the American Chemical Society 26907082 J Am Chem Soc 2016 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/26907082
Breaking the Fourth Wall: Modulating Quaternary Associations for Protein Regulation and Drug Discovery. Long MJC, Hnedzko D, Kim BK, Aye Y Chembiochem : a European journal of chemical biology 30589188 Chembiochem 2019 May 2 https://www.ncbi.nlm.nih.gov/pubmed/30589188
β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling. Long MJ, Lin HY, Parvez S, Zhao Y, Poganik JR, Huang P, Aye Y Cell chemical biology 28736239 Cell Chem Biol 2017 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/28736239
Getting the Message? Native Reactive Electrophiles Pass Two Out of Three Thresholds to be Bona Fide Signaling Mediators. Poganik JR, Long MJC, Aye Y BioEssays : news and reviews in molecular, cellular and developmental biology 29603288 Bioessays 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29603288
Ube2V2 Is a Rosetta Stone Bridging Redox and Ubiquitin Codes, Coordinating DNA Damage Responses. Zhao Y, Long MJC, Wang Y, Zhang S, Aye Y ACS central science 29532025 ACS Cent Sci 2018 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/29532025
A generalizable platform for interrogating target- and signal-specific consequences of electrophilic modifications in redox-dependent cell signaling. Lin HY, Haegele JA, Disare MT, Lin Q, Aye Y Journal of the American Chemical Society 25909755 J Am Chem Soc 2015 May 20 https://www.ncbi.nlm.nih.gov/pubmed/25909755
Chemical Biology Gateways to Mapping Location, Association, and Pathway Responsivity. Long MJC, Liu X, Aye Y Frontiers in chemistry 30949469 Front Chem 2019 https://www.ncbi.nlm.nih.gov/pubmed/30949469
REX technologies for profiling and decoding the electrophile signaling axes mediated by Rosetta Stone proteins. Long MJC, Urul DA, Aye Y Methods in enzymology 32046846 Methods Enzymol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32046846
Empowering Global Chemical Biology at the Dawn of the New Decade. Hoogendoorn S, Aye Y ACS chemical biology 32315151 ACS Chem Biol 2020 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/32315151
Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals. Poganik JR, Aye Y Frontiers in aging neuroscience 32116644 Front Aging Neurosci 2020 https://www.ncbi.nlm.nih.gov/pubmed/32116644
The mRNA-Binding Protein HuR Is a Kinetically-Privileged Electrophile Sensor. Poganik JR, Van Hall-Beauvais AK, Long MJC, Disare MT, Zhao Y, Aye Y Helvetica chimica acta 34113045 Helv Chim Acta 2020 May https://www.ncbi.nlm.nih.gov/pubmed/34113045
Substoichiometric hydroxynonenylation of a single protein recapitulates whole-cell-stimulated antioxidant response. Parvez S, Fu Y, Li J, Long MJ, Lin HY, Lee DK, Hu GS, Aye Y Journal of the American Chemical Society 25544059 J Am Chem Soc 2015 Jan 14 https://www.ncbi.nlm.nih.gov/pubmed/25544059
Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis. Long MJC, Zhao Y, Aye Y Cell chemical biology 31836351 Cell Chem Biol 2020 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/31836351
Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1. Poganik JR, Long MJC, Disare MT, Liu X, Chang SH, Hla T, Aye Y FASEB journal : official publication of the Federation of American Societies for Experimental Biology 31665914 FASEB J 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31665914
Modular Total Synthesis and Cell-Based Anticancer Activity Evaluation of Ouabagenin and Other Cardiotonic Steroids with Varying Degrees of Oxygenation. Khatri HR, Bhattarai B, Kaplan W, Li Z, Curtis Long MJ, Aye Y, Nagorny P Journal of the American Chemical Society 30802047 J Am Chem Soc 2019 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/30802047
Neighborhood watch: tools for defining locale-dependent subproteomes and their contextual signaling activities. Long MJC, Zhao Y, Aye Y RSC chemical biology 34458747 RSC Chem Biol 2020 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/34458747
Akt3 is a privileged first responder in isozyme-specific electrophile response. Long MJ, Parvez S, Zhao Y, Surya SL, Wang Y, Zhang S, Aye Y Nature chemical biology 28114274 Nat Chem Biol 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28114274
Subcellular Redox Targeting: Bridging in Vitro and in Vivo Chemical Biology. Long MJ, Poganik JR, Ghosh S, Aye Y ACS chemical biology 28068059 ACS Chem Biol 2017 Mar 17 https://www.ncbi.nlm.nih.gov/pubmed/28068059
The more the merrier: how homo-oligomerization alters the interactome and function of ribonucleotide reductase. Long MJC, Van Hall-Beauvais A, Aye Y Current opinion in chemical biology 31734537 Curr Opin Chem Biol 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31734537
Privileged Electrophile Sensors: A Resource for Covalent Drug Development. Long MJC, Aye Y Cell chemical biology 28648380 Cell Chem Biol 2017 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/28648380
Proteomics and Beyond: Cell Decision-Making Shaped by Reactive Electrophiles. Liu X, Long MJC, Aye Y Trends in biochemical sciences 30327250 Trends Biochem Sci 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30327250
Weighing up the Selenocysteome Uncovers New Sec-rets. Poganik JR, Aye Y Cell chemical biology 30445052 Cell Chem Biol 2018 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/30445052
The Die Is Cast: Precision Electrophilic Modifications Contribute to Cellular Decision Making. Long MJC, Aye Y Chemical research in toxicology 27617777 Chem Res Toxicol 2016 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/27617777
Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3. Fu Y, Long MJC, Wisitpitthaya S, Inayat H, Pierpont TM, Elsaid IM, Bloom JC, Ortega J, Weiss RS, Aye Y Nature chemical biology 30150681 Nat Chem Biol 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30150681
Genie in a bottle: controlled release helps tame natural polypharmacology? Long MJ, Liu X, Aye Y Current opinion in chemical biology 30913473 Curr Opin Chem Biol 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/30913473
Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor. Surya SL, Long MJC, Urul DA, Zhao Y, Mercer EJ, EIsaid IM, Evans T, Aye Y ACS chemical biology 29397684 ACS Chem Biol 2018 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/29397684
Redox Signaling by Reactive Electrophiles and Oxidants. Parvez S, Long MJC, Poganik JR, Aye Y Chemical reviews 30148624 Chem Rev 2018 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/30148624
Single-Protein-Specific Redox Targeting in Live Mammalian Cells and C. elegans. Van Hall-Beauvais A, Zhao Y, Urul DA, Long MJC, Aye Y Current protocols in chemical biology 30085412 Curr Protoc Chem Biol 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30085412
Cladribine and Fludarabine Nucleotides Induce Distinct Hexamers Defining a Common Mode of Reversible RNR Inhibition. Wisitpitthaya S, Zhao Y, Long MJ, Li M, Fletcher EA, Blessing WA, Weiss RS, Aye Y ACS chemical biology 27159113 ACS Chem Biol 2016 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/27159113
Getting the Right Grip? How Understanding Electrophile Selectivity Profiles Could Illuminate Our Understanding of Redox Signaling. Long MJC, Wang L, Aye Y Antioxidants & redox signaling 31578876 Antioxid Redox Signal 2020 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/31578876
Distribution shapes govern the discovery of predictive models for gene regulation. Munsky B, Li G, Fox ZR, Shepherd DP, Neuert G Proceedings of the National Academy of Sciences of the United States of America 29959206 Proc Natl Acad Sci U S A 2018 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/29959206
Finite state projection based bounds to compare chemical master equation models using single-cell data. Fox Z, Neuert G, Munsky B The Journal of chemical physics 27544081 J Chem Phys 2016 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/27544081
Modelling patient drug exposure profiles in vitro to narrow the valley of death. Leasure CS, Neuert G Nature reviews bioengineering 38873361 Nat Rev Bioeng 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38873361
Diverse Cell Stimulation Kinetics Identify Predictive Signal Transduction Models. Jashnsaz H, Fox ZR, Hughes JJ, Li G, Munsky B, Neuert G iScience 33083733 iScience 2020 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/33083733
Optimal Design of Single-Cell Experiments within Temporally Fluctuating Environments. Fox ZR, Neuert G, Munsky B Complexity 32982137 Complexity 2020 https://www.ncbi.nlm.nih.gov/pubmed/32982137
Phenotypic consequences of logarithmic signaling in MAPK stress response. Jashnsaz H, Neuert G bioRxiv : the preprint server for biology 38106069 bioRxiv 2023 Dec 7 https://www.ncbi.nlm.nih.gov/pubmed/38106069
Generating kinetic environments to study dynamic cellular processes in single cells. Thiemicke A, Jashnsaz H, Li G, Neuert G Scientific reports 31300695 Sci Rep 2019 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/31300695
Multiplex RNA single molecule FISH of inducible mRNAs in single yeast cells. Li G, Neuert G Scientific data 31209217 Sci Data 2019 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/31209217
A rate threshold mechanism regulates MAPK stress signaling and survival. Johnson AN, Li G, Jashnsaz H, Thiemicke A, Kesler BK, Rogers DC, Neuert G Proceedings of the National Academy of Sciences of the United States of America 33443180 Proc Natl Acad Sci U S A 2021 Jan 12 https://www.ncbi.nlm.nih.gov/pubmed/33443180
Kinetics of osmotic stress regulate a cell fate switch of cell survival. Thiemicke A, Neuert G Science advances 33608274 Sci Adv 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33608274
Rate thresholds in cell signaling have functional and phenotypic consequences in non-linear time-dependent environments. Thiemicke A, Neuert G Frontiers in cell and developmental biology 37025183 Front Cell Dev Biol 2023 https://www.ncbi.nlm.nih.gov/pubmed/37025183
Automated cell boundary and 3D nuclear segmentation of cells in suspension. Kesler B, Li G, Thiemicke A, Venkat R, Neuert G Scientific reports 31308458 Sci Rep 2019 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/31308458
Integrating single-molecule experiments and discrete stochastic models to understand heterogeneous gene transcription dynamics. Munsky B, Fox Z, Neuert G Methods (San Diego, Calif.) 26079925 Methods 2015 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/26079925
From analog to digital models of gene regulation. Munsky B, Neuert G Physical biology 26086470 Phys Biol 2015 Jun 18 https://www.ncbi.nlm.nih.gov/pubmed/26086470
TrueSpot: A robust automated tool for quantifying signal puncta in fluorescent imaging. Hospelhorn BG, Kesler BK, Jashnsaz H, Neuert G bioRxiv : the preprint server for biology 39868229 bioRxiv 2025 Jan 14 https://www.ncbi.nlm.nih.gov/pubmed/39868229
Chemoselective ratiometric imaging of protein S-sulfenylation. Tom CTMB, Crellin JE, Motiwala HF, Stone MB, Davda D, Walker W, Kuo YH, Hernandez JL, Labby KJ, Gomez-Rodriguez L, Jenkins PM, Veatch SL, Martin BR Chemical communications (Cambridge, England) 28613292 Chem Commun (Camb) 2017 Jun 29 https://www.ncbi.nlm.nih.gov/pubmed/28613292
Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2). Won SJ, Davda D, Labby KJ, Hwang SY, Pricer R, Majmudar JD, Armacost KA, Rodriguez LA, Rodriguez CL, Chong FS, Torossian KA, Palakurthi J, Hur ES, Meagher JL, Brooks CL 3rd, Stuckey JA, Martin BR ACS chemical biology 27748579 ACS Chem Biol 2016 Dec 16 https://www.ncbi.nlm.nih.gov/pubmed/27748579
Variable-Velocity Traveling-Wave Ion Mobility Separation Enhancing Peak Capacity for Data-Independent Acquisition Proteomics. Haynes SE, Polasky DA, Dixit SM, Majmudar JD, Neeson K, Ruotolo BT, Martin BR Analytical chemistry 28471653 Anal Chem 2017 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/28471653
Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling. Motiwala HF, Kuo YH, Stinger BL, Palfey BA, Martin BR Journal of the American Chemical Society 31881155 J Am Chem Soc 2020 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/31881155
Global Analysis of Palmitoylated Proteins in Toxoplasma gondii. Foe IT, Child MA, Majmudar JD, Krishnamurthy S, van der Linden WA, Ward GE, Martin BR, Bogyo M Cell host & microbe 26468752 Cell Host Microbe 2015 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/26468752
Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes. Xu H, Majmudar JD, Davda D, Ghanakota P, Kim KH, Carlson HA, Showalter HD, Martin BR, Amidon GL Molecular pharmaceutics 26262434 Mol Pharm 2015 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/26262434
Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle. Won SJ, Martin BR ACS chemical biology 29733200 ACS Chem Biol 2018 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/29733200
APT2 Inhibition Restores Scribble Localization and S-Palmitoylation in Snail-Transformed Cells. Hernandez JL, Davda D, Cheung See Kit M, Majmudar JD, Won SJ, Gang M, Pasupuleti SC, Choi AI, Bartkowiak CM, Martin BR Cell chemical biology 28065656 Cell Chem Biol 2017 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/28065656
Activated G Protein Gαs Samples Multiple Endomembrane Compartments. Martin BR, Lambert NA The Journal of biological chemistry 27528603 J Biol Chem 2016 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/27528603
Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly. ElAzzouny M, Tom CT, Evans CR, Olson LL, Tanga MJ, Gallagher KA, Martin BR, Burant CF The Journal of biological chemistry 28188288 J Biol Chem 2017 Mar 24 https://www.ncbi.nlm.nih.gov/pubmed/28188288
Harnessing Redox Cross-Reactivity To Profile Distinct Cysteine Modifications. Majmudar JD, Konopko AM, Labby KJ, Tom CT, Crellin JE, Prakash A, Martin BR Journal of the American Chemical Society 26780921 J Am Chem Soc 2016 Feb 17 https://www.ncbi.nlm.nih.gov/pubmed/26780921
Correlated S-palmitoylation profiling of Snail-induced epithelial to mesenchymal transition. Hernandez JL, Davda D, Majmudar JD, Won SJ, Prakash A, Choi AI, Martin BR Molecular bioSystems 27030425 Mol Biosyst 2016 May https://www.ncbi.nlm.nih.gov/pubmed/27030425
Targeted Annotation of S-Sulfonylated Peptides by Selective Infrared Multiphoton Dissociation Mass Spectrometry. Borotto NB, McClory PJ, Martin BR, Håkansson K Analytical chemistry 28708386 Anal Chem 2017 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/28708386
DIA-SIFT: A Precursor and Product Ion Filter for Accurate Stable Isotope Data-Independent Acquisition Proteomics. Haynes SE, Majmudar JD, Martin BR Analytical chemistry 29989796 Anal Chem 2018 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/29989796
Affinity-Based Selectivity Profiling of an In-Class Selective Competitive Inhibitor of Acyl Protein Thioesterase 2. Won SJ, Eschweiler JD, Majmudar JD, Chong FS, Hwang SY, Ruotolo BT, Martin BR ACS medicinal chemistry letters 28197315 ACS Med Chem Lett 2017 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/28197315
Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation. Zhao D, Yin Z, Soellner MB, Martin BR Cell chemical biology 33730553 Cell Chem Biol 2021 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/33730553
Profiling Protein S-Sulfination with Maleimide-Linked Probes. Kuo YH, Konopko AM, Borotto NB, Majmudar JD, Haynes SE, Martin BR Chembiochem : a European journal of chemical biology 28809078 Chembiochem 2017 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/28809078
HDAC8 Substrates Identified by Genetically Encoded Active Site Photocrosslinking. Lopez JE, Haynes SE, Majmudar JD, Martin BR, Fierke CA Journal of the American Chemical Society 29035536 J Am Chem Soc 2017 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/29035536
Protein depalmitoylases. Won SJ, Cheung See Kit M, Martin BR Critical reviews in biochemistry and molecular biology 29239216 Crit Rev Biochem Mol Biol 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29239216
Enrichment of S-Palmitoylated Proteins for Mass Spectrometry Analysis. Cheung See Kit M, Martin BR Methods in molecular biology (Clifton, N.J.) 31152396 Methods Mol Biol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31152396
Free Radical Initiated Peptide Sequencing for Direct Site Localization of Sulfation and Phosphorylation with Negative Ion Mode Mass Spectrometry. Borotto NB, Ileka KM, Tom CATMB, Martin BR, Håkansson K Analytical chemistry 30063332 Anal Chem 2018 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/30063332
Placing and shaping liposomes with reconfigurable DNA nanocages. Zhang Z, Yang Y, Pincet F, Llaguno MC, Lin C Nature chemistry 28644472 Nat Chem 2017 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/28644472
DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells. Williams ND, Landajuela A, Kasula RK, Zhou W, Powell JT, Xi Z, Isaacs FJ, Berro J, Toomre D, Karatekin E, Lin C Nano letters 33164530 Nano Lett 2020 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/33164530
DNA Origami Post-Processing by CRISPR-Cas12a. Xiong Q, Xie C, Zhang Z, Liu L, Powell JT, Shen Q, Lin C Angewandte Chemie (International ed. in English) 31883145 Angew Chem Int Ed Engl 2020 Mar 2 https://www.ncbi.nlm.nih.gov/pubmed/31883145
FisB relies on homo-oligomerization and lipid binding to catalyze membrane fission in bacteria. Landajuela A, Braun M, Rodrigues CDA, Martínez-Calvo A, Doan T, Horenkamp F, Andronicos A, Shteyn V, Williams ND, Lin C, Wingreen NS, Rudner DZ, Karatekin E PLoS biology 34185788 PLoS Biol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34185788
Engineering Lipid Membranes with Programmable DNA Nanostructures. Shen Q, Grome MW, Yang Y, Lin C Advanced biosystems 31934608 Adv Biosyst 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31934608
A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement. Fisher PDE, Shen Q, Akpinar B, Davis LK, Chung KKH, Baddeley D, Šarić A, Melia TJ, Hoogenboom BW, Lin C, Lusk CP ACS nano 29350911 ACS Nano 2018 Feb 27 https://www.ncbi.nlm.nih.gov/pubmed/29350911
Vesicle Tubulation with Self-Assembling DNA Nanosprings. Grome MW, Zhang Z, Pincet F, Lin C Angewandte Chemie (International ed. in English) 29575478 Angew Chem Int Ed Engl 2018 May 4 https://www.ncbi.nlm.nih.gov/pubmed/29575478
Stiffness and Membrane Anchor Density Modulate DNA-Nanospring-Induced Vesicle Tubulation. Grome MW, Zhang Z, Lin C ACS applied materials & interfaces 31252462 ACS Appl Mater Interfaces 2019 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/31252462
A programmable DNA-origami platform for studying lipid transfer between bilayers. Bian X, Zhang Z, Xiong Q, De Camilli P, Lin C Nature chemical biology 31320758 Nat Chem Biol 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31320758
DNA Origami Rotaxanes: Tailored Synthesis and Controlled Structure Switching. Powell JT, Akhuetie-Oni BO, Zhang Z, Lin C Angewandte Chemie (International ed. in English) 27527591 Angew Chem Int Ed Engl 2016 Sep 12 https://www.ncbi.nlm.nih.gov/pubmed/27527591
Sorting sub-150-nm liposomes of distinct sizes by DNA-brick-assisted centrifugation. Yang Y, Wu Z, Wang L, Zhou K, Xia K, Xiong Q, Liu L, Zhang Z, Chapman ER, Xiong Y, Melia TJ, Karatekin E, Gu H, Lin C Nature chemistry 33785892 Nat Chem 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33785892
Directing reconfigurable DNA nanoarrays. Yang Y, Lin C Science (New York, N.Y.) 28751594 Science 2017 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/28751594
Fluorogenic DNA-PAINT for faster, low-background super-resolution imaging. Chung KKH, Zhang Z, Kidd P, Zhang Y, Williams ND, Rollins B, Yang Y, Lin C, Baddeley D, Bewersdorf J Nature methods 35501386 Nat Methods 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35501386
A systematic comparison of error correction enzymes by next-generation sequencing. Lubock NB, Zhang D, Sidore AM, Church GM, Kosuri S Nucleic acids research 28911123 Nucleic Acids Res 2017 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/28911123
Dissection of c-AMP Response Element Architecture by Using Genomic and Episomal Massively Parallel Reporter Assays. Davis JE, Insigne KD, Jones EM, Hastings QA, Boldridge WC, Kosuri S Cell systems 32603702 Cell Syst 2020 Jul 22 https://www.ncbi.nlm.nih.gov/pubmed/32603702
Systematic Dissection of Sequence Elements Controlling σ70 Promoters Using a Genomically Encoded Multiplexed Reporter Assay in Escherichia coli. Urtecho G, Tripp AD, Insigne KD, Kim H, Kosuri S Biochemistry 29388765 Biochemistry 2019 Mar 19 https://www.ncbi.nlm.nih.gov/pubmed/29388765
Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems. Yu TC, Liu WL, Brinck MS, Davis JE, Shek J, Bower G, Einav T, Insigne KD, Phillips R, Kosuri S, Urtecho G Nature communications 33436562 Nat Commun 2021 Jan 12 https://www.ncbi.nlm.nih.gov/pubmed/33436562
Multiplexed gene synthesis in emulsions for exploring protein functional landscapes. Plesa C, Sidore AM, Lubock NB, Zhang D, Kosuri S Science (New York, N.Y.) 29301959 Science 2018 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/29301959
A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions. Chong R, Insigne KD, Yao D, Burghard CP, Wang J, Hsiao YE, Jones EM, Goodman DB, Xiao X, Kosuri S Molecular cell 30503770 Mol Cell 2019 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/30503770
Highly parallel genome variant engineering with CRISPR-Cas9. Sadhu MJ, Bloom JS, Day L, Siegel JJ, Kosuri S, Kruglyak L Nature genetics 29632376 Nat Genet 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29632376
Structural and functional characterization of G protein-coupled receptors with deep mutational scanning. Jones EM, Lubock NB, Venkatakrishnan AJ, Wang J, Tseng AM, Paggi JM, Latorraca NR, Cancilla D, Satyadi M, Davis JE, Babu MM, Dror RO, Kosuri S eLife 33084570 Elife 2020 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/33084570
Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross. Renganaath K, Chong R, Day L, Kosuri S, Kruglyak L, Albert FW eLife 33179598 Elife 2020 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/33179598
A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing. Jones EM, Jajoo R, Cancilla D, Lubock NB, Wang J, Satyadi M, Chong R, de March C, Bloom JS, Matsunami H, Kosuri S Cell systems 30904378 Cell Syst 2019 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/30904378
Metagenomic mining of regulatory elements enables programmable species-selective gene expression. Johns NI, Gomes ALC, Yim SS, Yang A, Blazejewski T, Smillie CS, Smith MB, Alm EJ, Kosuri S, Wang HH Nature methods 30052624 Nat Methods 2018 May https://www.ncbi.nlm.nih.gov/pubmed/30052624
DropSynth 2.0: high-fidelity multiplexed gene synthesis in emulsions. Sidore AM, Plesa C, Samson JA, Lubock NB, Kosuri S Nucleic acids research 32692349 Nucleic Acids Res 2020 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/32692349
A multiplexed bacterial two-hybrid for rapid characterization of protein-protein interactions and iterative protein design. Boldridge WC, Ljubetič A, Kim H, Lubock N, Szilágyi D, Lee J, Brodnik A, Jerala R, Kosuri S Nature communications 37532706 Nat Commun 2023 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/37532706
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Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli. Alexander M, Ramstead AG, Bauer KM, Lee SH, Runtsch MC, Wallace J, Huffaker TB, Larsen DK, Tolmachova T, Seabra MC, Round JL, Ward DM, O'Connell RM Journal of immunology (Baltimore, Md. : 1950) 28978688 J Immunol 2017 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/28978688
MicroRNAs and acute myeloid leukemia: therapeutic implications and emerging concepts. Wallace JA, O'Connell RM Blood 28751524 Blood 2017 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/28751524
MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi. Lochhead RB, Ma Y, Zachary JF, Baltimore D, Zhao JL, Weis JH, O'Connell RM, Weis JJ PLoS pathogens 24967703 PLoS Pathog 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24967703
miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation. Hu R, Kagele DA, Huffaker TB, Runtsch MC, Alexander M, Liu J, Bake E, Su W, Williams MA, Rao DS, Möller T, Garden GA, Round JL, O'Connell RM Immunity 25367574 Immunity 2014 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/25367574
miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response. Wallace JA, Kagele DA, Eiring AM, Kim CN, Hu R, Runtsch MC, Alexander M, Huffaker TB, Lee SH, Patel AB, Mosbruger TL, Voth WP, Rao DS, Miles RR, Round JL, Deininger MW, O'Connell RM Blood 28432220 Blood 2017 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/28432220
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis. Gogokhia L, Buhrke K, Bell R, Hoffman B, Brown DG, Hanke-Gogokhia C, Ajami NJ, Wong MC, Ghazaryan A, Valentine JF, Porter N, Martens E, O'Connell R, Jacob V, Scherl E, Crawford C, Stephens WZ, Casjens SR, Longman RS, Round JL Cell host & microbe 30763538 Cell Host Microbe 2019 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/30763538
Colitis reduces active social engagement in mice and is ameliorated by supplementation with human microbiota members. Brown DG, Murphy M, Cadeddu R, Bell R, Weis A, Chiaro T, Klag K, Morgan J, Coon H, Stephens WZ, Bortolato M, Round JL Nature communications 38553486 Nat Commun 2024 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/38553486
Choosing the right pharmacotherapeutic strategy for HIV maintenance in patients with alcohol addiction. Kodidela S, Kumar S Expert opinion on pharmacotherapy 30724618 Expert Opin Pharmacother 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30724618
Characterizing RNA structures in vitro and in vivo with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq). Watters KE, Yu AM, Strobel EJ, Settle AH, Lucks JB Methods (San Diego, Calif.) 27064082 Methods 2016 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/27064082
Simultaneous characterization of cellular RNA structure and function with in-cell SHAPE-Seq. Watters KE, Abbott TR, Lucks JB Nucleic acids research 26350218 Nucleic Acids Res 2016 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/26350218
Characterizing the Structure-Function Relationship of a Naturally Occurring RNA Thermometer. Meyer S, Carlson PD, Lucks JB Biochemistry 29172455 Biochemistry 2017 Dec 26 https://www.ncbi.nlm.nih.gov/pubmed/29172455
Computationally reconstructing cotranscriptional RNA folding from experimental data reveals rearrangement of non-native folding intermediates. Yu AM, Gasper PM, Cheng L, Lai LB, Kaur S, Gopalan V, Chen AA, Lucks JB Molecular cell 33453165 Mol Cell 2021 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/33453165
Distributed biotin-streptavidin transcription roadblocks for mapping cotranscriptional RNA folding. Strobel EJ, Watters KE, Nedialkov Y, Artsimovitch I, Lucks JB Nucleic acids research 28398514 Nucleic Acids Res 2017 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/28398514
SHAPE-Seq 2.0: systematic optimization and extension of high-throughput chemical probing of RNA secondary structure with next generation sequencing. Loughrey D, Watters KE, Settle AH, Lucks JB Nucleic acids research 25303992 Nucleic Acids Res 2014 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/25303992
SnapShot: RNA Structure Probing Technologies. Carlson PD, Evans ME, Yu AM, Strobel EJ, Lucks JB Cell 30290145 Cell 2018 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/30290145
Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements. Watters KE, Choudhary K, Aviran S, Lucks JB, Perry KL, Thompson JR Nucleic acids research 29294088 Nucleic Acids Res 2018 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/29294088
RNA systems biology: uniting functional discoveries and structural tools to understand global roles of RNAs. Strobel EJ, Watters KE, Loughrey D, Lucks JB Current opinion in biotechnology 27132125 Curr Opin Biotechnol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27132125
Using in-cell SHAPE-Seq and simulations to probe structure-function design principles of RNA transcriptional regulators. Takahashi MK, Watters KE, Gasper PM, Abbott TR, Carlson PD, Chen AA, Lucks JB RNA (New York, N.Y.) 27103533 RNA 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27103533
Mapping RNA Structure In Vitro with SHAPE Chemistry and Next-Generation Sequencing (SHAPE-Seq). Watters KE, Lucks JB Methods in molecular biology (Clifton, N.J.) 27665597 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/27665597
DUETT quantitatively identifies known and novel events in nascent RNA structural dynamics from chemical probing data. Xue AY, Yu AM, Lucks JB, Bagheri N Bioinformatics (Oxford, England) 31389563 Bioinformatics 2019 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/31389563
Computational design of three-dimensional RNA structure and function. Yesselman JD, Eiler D, Carlson ED, Gotrik MR, d'Aquino AE, Ooms AN, Kladwang W, Carlson PD, Shi X, Costantino DA, Herschlag D, Lucks JB, Jewett MC, Kieft JS, Das R Nature nanotechnology 31427748 Nat Nanotechnol 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31427748
Cotranscriptional folding of a riboswitch at nucleotide resolution. Watters KE, Strobel EJ, Yu AM, Lis JT, Lucks JB Nature structural & molecular biology 27798597 Nat Struct Mol Biol 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27798597
High-throughput determination of RNA structures. Strobel EJ, Yu AM, Lucks JB Nature reviews. Genetics 30054568 Nat Rev Genet 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30054568
A ligand-gated strand displacement mechanism for ZTP riboswitch transcription control. Strobel EJ, Cheng L, Berman KE, Carlson PD, Lucks JB Nature chemical biology 31636437 Nat Chem Biol 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31636437
Inhibiting the Evolution of Antibiotic Resistance. Ragheb MN, Thomason MK, Hsu C, Nugent P, Gage J, Samadpour AN, Kariisa A, Merrikh CN, Miller SI, Sherman DR, Merrikh H Molecular cell 30449724 Mol Cell 2019 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/30449724
Spatial and Temporal Control of Evolution through Replication-Transcription Conflicts. Merrikh H Trends in microbiology 28216294 Trends Microbiol 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28216294
Crystal structure of a membrane-bound O-acyltransferase. Ma D, Wang Z, Merrikh CN, Lang KS, Lu P, Li X, Merrikh H, Rao Z, Xu W Nature 30283133 Nature 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30283133
Gene inversion potentiates bacterial evolvability and virulence. Merrikh CN, Merrikh H Nature communications 30405125 Nat Commun 2018 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/30405125
Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis. Lang KS, Hall AN, Merrikh CN, Ragheb M, Tabakh H, Pollock AJ, Woodward JJ, Dreifus JE, Merrikh H Cell 28802046 Cell 2017 Aug 10 https://www.ncbi.nlm.nih.gov/pubmed/28802046
The B. subtilis Accessory Helicase PcrA Facilitates DNA Replication through Transcription Units. Merrikh CN, Brewer BJ, Merrikh H PLoS genetics 26070154 PLoS Genet 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/26070154
Replication Restart after Replication-Transcription Conflicts Requires RecA in Bacillus subtilis. Million-Weaver S, Samadpour AN, Merrikh H Journal of bacteriology 25939832 J Bacteriol 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/25939832
Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts. Lang KS, Merrikh H Cell reports 33657379 Cell Rep 2021 Mar 2 https://www.ncbi.nlm.nih.gov/pubmed/33657379
The Accelerated Evolution of Lagging Strand Genes Is Independent of Sequence Context. Merrikh CN, Weiss E, Merrikh H Genome biology and evolution 28039230 Genome Biol Evol 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/28039230
The bacterial replisome has factory-like localization. Mangiameli SM, Cass JA, Merrikh H, Wiggins PA Current genetics 29632994 Curr Genet 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/29632994
The Clash of Macromolecular Titans: Replication-Transcription Conflicts in Bacteria. Lang KS, Merrikh H Annual review of microbiology 29856930 Annu Rev Microbiol 2018 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/29856930
DNA gyrase activity regulates DnaA-dependent replication initiation in Bacillus subtilis. Samadpour AN, Merrikh H Molecular microbiology 29396913 Mol Microbiol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29396913
An underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis. Million-Weaver S, Samadpour AN, Moreno-Habel DA, Nugent P, Brittnacher MJ, Weiss E, Hayden HS, Miller SI, Liachko I, Merrikh H Proceedings of the National Academy of Sciences of the United States of America 25713353 Proc Natl Acad Sci U S A 2015 Mar 10 https://www.ncbi.nlm.nih.gov/pubmed/25713353
Current outcomes when optimizing 'standard' sample preparation for single-particle cryo-EM. Carragher B, Cheng Y, Frost A, Glaeser RM, Lander GC, Nogales E, Wang HW Journal of microscopy 31553060 J Microsc 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31553060
Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins. Kalia R, Frost A Molecular biology of the cell 31365329 Mol Biol Cell 2019 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/31365329
Membrane constriction and thinning by sequential ESCRT-III polymerization. Nguyen HC, Talledge N, McCullough J, Sharma A, Moss FR 3rd, Iwasa JH, Vershinin MD, Sundquist WI, Frost A Nature structural & molecular biology 32251413 Nat Struct Mol Biol 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32251413
Structural and functional studies of membrane remodeling machines. Kalia R, Talledge N, Frost A Methods in cell biology 25997348 Methods Cell Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/25997348
In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing. Osuna BA, Howard CJ, Kc S, Frost A, Weinberg DE eLife 28718767 Elife 2017 Jul 18 https://www.ncbi.nlm.nih.gov/pubmed/28718767
Structure and membrane remodeling activity of ESCRT-III helical polymers. McCullough J, Clippinger AK, Talledge N, Skowyra ML, Saunders MG, Naismith TV, Colf LA, Afonine P, Arthur C, Sundquist WI, Hanson PI, Frost A Science (New York, N.Y.) 26634441 Science 2015 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/26634441
LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. Gu M, LaJoie D, Chen OS, von Appen A, Ladinsky MS, Redd MJ, Nikolova L, Bjorkman PJ, Sundquist WI, Ullman KS, Frost A Proceedings of the National Academy of Sciences of the United States of America 28242692 Proc Natl Acad Sci U S A 2017 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/28242692
Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P Science (New York, N.Y.) 29599213 Science 2018 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/29599213
Cell biology: Double agents for mitochondrial division. McBride HM, Frost A Nature 27880759 Nature 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27880759
A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP. Hwang J, Ribbens D, Raychaudhuri S, Cairns L, Gu H, Frost A, Urban S, Espenshade PJ The EMBO journal 27655872 EMBO J 2016 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/27655872
Structural inhibition of dynamin-mediated membrane fission by endophilin. Hohendahl A, Talledge N, Galli V, Shen PS, Humbert F, De Camilli P, Frost A, Roux A eLife 28933693 Elife 2017 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/28933693
Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A Science (New York, N.Y.) 25554787 Science 2015 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/25554787
Functional role of PGAM5 multimeric assemblies and their polymerization into filaments. Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N Nature communications 30705304 Nat Commun 2019 Jan 31 https://www.ncbi.nlm.nih.gov/pubmed/30705304
Structures, Functions, and Dynamics of ESCRT-III/Vps4 Membrane Remodeling and Fission Complexes. McCullough J, Frost A, Sundquist WI Annual review of cell and developmental biology 30095293 Annu Rev Cell Dev Biol 2018 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/30095293
A Tunable Microfluidic Device Enables Cargo Encapsulation by Cell- or Organelle-Sized Lipid Vesicles Comprising Asymmetric Lipid Bilayers. Romanov V, McCullough J, Gale BK, Frost A Advanced biosystems 31428671 Adv Biosyst 2019 Jul https://www.ncbi.nlm.nih.gov/pubmed/31428671
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. Miller-Vedam LE, Bräuning B, Popova KD, Schirle Oakdale NT, Bonnar JL, Prabu JR, Boydston EA, Sevillano N, Shurtleff MJ, Stroud RM, Craik CS, Schulman BA, Frost A, Weissman JS eLife 33236988 Elife 2020 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/33236988
Photocatalytic LPOR forms helical lattices that shape membranes for chlorophyll synthesis. Nguyen HC, Melo AA, Kruk J, Frost A, Gabruk M Nature plants 33875834 Nat Plants 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33875834
Brominated lipid probes expose structural asymmetries in constricted membranes. Moss FR 3rd, Lincoff J, Tucker M, Mohammed A, Grabe M, Frost A Nature structural & molecular biology 36624348 Nat Struct Mol Biol 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/36624348
Vms1p is a release factor for the ribosome-associated quality control complex. Zurita Rendón O, Fredrickson EK, Howard CJ, Van Vranken J, Fogarty S, Tolley ND, Kalia R, Osuna BA, Shen PS, Hill CP, Frost A, Rutter J Nature communications 29875445 Nat Commun 2018 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/29875445
Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex. Heider MR, Gu M, Duffy CM, Mirza AM, Marcotte LL, Walls AC, Farrall N, Hakhverdyan Z, Field MC, Rout MP, Frost A, Munson M Nature structural & molecular biology 26656853 Nat Struct Mol Biol 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/26656853
Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission. Koirala S, Guo Q, Kalia R, Bui HT, Eckert DM, Frost A, Shaw JM Proceedings of the National Academy of Sciences of the United States of America 23530241 Proc Natl Acad Sci U S A 2013 Apr 9 https://www.ncbi.nlm.nih.gov/pubmed/23530241
eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A Science (New York, N.Y.) 31048491 Science 2019 May 3 https://www.ncbi.nlm.nih.gov/pubmed/31048491
Structural basis of mitochondrial receptor binding and constriction by DRP1. Kalia R, Wang RY, Yusuf A, Thomas PV, Agard DA, Shaw JM, Frost A Nature 29899447 Nature 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29899447
Membrane fission by dynamin: what we know and what we need to know. Antonny B, Burd C, De Camilli P, Chen E, Daumke O, Faelber K, Ford M, Frolov VA, Frost A, Hinshaw JE, Kirchhausen T, Kozlov MM, Lenz M, Low HH, McMahon H, Merrifield C, Pollard TD, Robinson PJ, Roux A, Schmid S The EMBO journal 27670760 EMBO J 2016 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/27670760
The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH, Weissman JS eLife 29809151 Elife 2018 May 29 https://www.ncbi.nlm.nih.gov/pubmed/29809151
FDM 3D Printing of High-Pressure, Heat-Resistant, Transparent Microfluidic Devices. Romanov V, Samuel R, Chaharlang M, Jafek AR, Frost A, Gale BK Analytical chemistry 30071717 Anal Chem 2018 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/30071717
Exocyst structural changes associated with activation of tethering downstream of Rho/Cdc42 GTPases. Rossi G, Lepore D, Kenner L, Czuchra AB, Plooster M, Frost A, Munson M, Brennwald P The Journal of cell biology 31904797 J Cell Biol 2020 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/31904797
LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation. von Appen A, LaJoie D, Johnson IE, Trnka MJ, Pick SM, Burlingame AL, Ullman KS, Frost A Nature 32494070 Nature 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32494070
CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, Weinberg DE, Weissman JS Science (New York, N.Y.) 28751611 Science 2017 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/28751611
Structural basis of TRPV1 modulation by endogenous bioactive lipids. Arnold WR, Mancino A, Moss FR 3rd, Frost A, Julius D, Cheng Y Nature structural & molecular biology 38698206 Nat Struct Mol Biol 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/38698206
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Mapping human microbiome drug metabolism by gut bacteria and their genes. Zimmermann M, Zimmermann-Kogadeeva M, Wegmann R, Goodman AL Nature 31158845 Nature 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31158845
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Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. Stein BD, Calzolari D, Hellberg K, Hu YS, He L, Hung CM, Toyama EQ, Ross DS, Lillemeier BF, Cantley LC, Yates JR 3rd, Shaw RJ Cell reports 31801093 Cell Rep 2019 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/31801093
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Srs2 prevents Rad51 filament formation by repetitive motion on DNA. Qiu Y, Antony E, Doganay S, Koh HR, Lohman TM, Myong S Nature communications 23939144 Nat Commun 2013 https://www.ncbi.nlm.nih.gov/pubmed/23939144
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G-quadruplex conformation and dynamics are determined by loop length and sequence. Tippana R, Xiao W, Myong S Nucleic acids research 24920827 Nucleic Acids Res 2014 Jul https://www.ncbi.nlm.nih.gov/pubmed/24920827
Single-molecule real-time detection of telomerase extension activity. Hwang H, Opresko P, Myong S Scientific reports 25263700 Sci Rep 2014 Sep 29 https://www.ncbi.nlm.nih.gov/pubmed/25263700
The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics. Elbaum-Garfinkle S, Kim Y, Szczepaniak K, Chen CC, Eckmann CR, Myong S, Brangwynne CP Proceedings of the National Academy of Sciences of the United States of America 26015579 Proc Natl Acad Sci U S A 2015 Jun 9 https://www.ncbi.nlm.nih.gov/pubmed/26015579
Visualizing repetitive diffusion activity of double-strand RNA binding proteins by single molecule fluorescence assays. Koh HR, Wang X, Myong S Methods (San Diego, Calif.) 27012177 Methods 2016 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/27012177
RNA stem structure governs coupling of dicing and gene silencing in RNA interference. Koh HR, Ghanbariniaki A, Myong S Proceedings of the National Academy of Sciences of the United States of America 29133395 Proc Natl Acad Sci U S A 2017 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/29133395
Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Chen MC, Tippana R, Demeshkina NA, Murat P, Balasubramanian S, Myong S, Ferré-D'Amaré AR Nature 29899445 Nature 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29899445
RNA Remodeling Activity of DEAD Box Proteins Tuned by Protein Concentration, RNA Length, and ATP. Kim Y, Myong S Molecular cell 27546789 Mol Cell 2016 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/27546789
Substrate recognition and specificity of double-stranded RNA binding proteins. Vuković L, Koh HR, Myong S, Schulten K Biochemistry 24801449 Biochemistry 2014 Jun 3 https://www.ncbi.nlm.nih.gov/pubmed/24801449
Single-Cell Imaging Approaches for Studying Small-RNA-Induced Gene Regulation. Koh HR, Myong S Biophysical journal 29970232 Biophys J 2018 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/29970232
G-Quadruplex and Protein Binding by Single-Molecule FRET Microscopy. Lee CY, McNerney C, Myong S Methods in molecular biology (Clifton, N.J.) 31444758 Methods Mol Biol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31444758
Dynamic profiling of double-stranded RNA binding proteins. Wang X, Vukovic L, Koh HR, Schulten K, Myong S Nucleic acids research 26184879 Nucleic Acids Res 2015 Sep 3 https://www.ncbi.nlm.nih.gov/pubmed/26184879
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer. Bell RJ, Rube HT, Kreig A, Mancini A, Fouse SD, Nagarajan RP, Choi S, Hong C, He D, Pekmezci M, Wiencke JK, Wrensch MR, Chang SM, Walsh KM, Myong S, Song JS, Costello JF Science (New York, N.Y.) 25977370 Science 2015 May 29 https://www.ncbi.nlm.nih.gov/pubmed/25977370
Molecular mechanism of resolving trinucleotide repeat hairpin by helicases. Qiu Y, Niu H, Vukovic L, Sung P, Myong S Structure (London, England : 1993) 26004439 Structure 2015 Jun 2 https://www.ncbi.nlm.nih.gov/pubmed/26004439
POT1-TPP1 regulates telomeric overhang structural dynamics. Hwang H, Buncher N, Opresko PL, Myong S Structure (London, England : 1993) 22981946 Structure 2012 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/22981946
The Chd1 Chromatin Remodeler Shifts Nucleosomal DNA Bidirectionally as a Monomer. Qiu Y, Levendosky RF, Chakravarthy S, Patel A, Bowman GD, Myong S Molecular cell 28943314 Mol Cell 2017 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/28943314
mRNA structure determines specificity of a polyQ-driven phase separation. Langdon EM, Qiu Y, Ghanbari Niaki A, McLaughlin GA, Weidmann CA, Gerbich TM, Smith JA, Crutchley JM, Termini CM, Weeks KM, Myong S, Gladfelter AS Science (New York, N.Y.) 29650703 Science 2018 May 25 https://www.ncbi.nlm.nih.gov/pubmed/29650703
Quantitative analysis and prediction of G-quadruplex forming sequences in double-stranded DNA. Kim M, Kreig A, Lee CY, Rube HT, Calvert J, Song JS, Myong S Nucleic acids research 27095201 Nucleic Acids Res 2016 Jun 2 https://www.ncbi.nlm.nih.gov/pubmed/27095201
Oxidative guanine base damage regulates human telomerase activity. Fouquerel E, Lormand J, Bose A, Lee HT, Kim GS, Li J, Sobol RW, Freudenthal BD, Myong S, Opresko PL Nature structural & molecular biology 27820808 Nat Struct Mol Biol 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27820808
RNA Scanning of a Molecular Machine with a Built-in Ruler. Koh HR, Kidwell MA, Doudna J, Myong S Journal of the American Chemical Society 27958730 J Am Chem Soc 2017 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/27958730
Single-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicases. Tippana R, Hwang H, Opresko PL, Bohr VA, Myong S Proceedings of the National Academy of Sciences of the United States of America 27407146 Proc Natl Acad Sci U S A 2016 Jul 26 https://www.ncbi.nlm.nih.gov/pubmed/27407146
ATP-independent diffusion of double-stranded RNA binding proteins. Koh HR, Kidwell MA, Ragunathan K, Doudna JA, Myong S Proceedings of the National Academy of Sciences of the United States of America 23251028 Proc Natl Acad Sci U S A 2013 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/23251028
Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins. Hwang H, Kreig A, Calvert J, Lormand J, Kwon Y, Daley JM, Sung P, Opresko PL, Myong S Structure (London, England : 1993) 24836024 Structure 2014 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/24836024
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An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. Zhao Z, Lee RT, Pusapati GV, Iyu A, Rohatgi R, Ingham PW EMBO reports 27113758 EMBO Rep 2016 May https://www.ncbi.nlm.nih.gov/pubmed/27113758
Lipid droplets can promote drug accumulation and activation. Dubey R, Stivala CE, Nguyen HQ, Goo YH, Paul A, Carette JE, Trost BM, Rohatgi R Nature chemical biology 31932720 Nat Chem Biol 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31932720
Phase separation-deficient TDP43 remains functional in splicing. Schmidt HB, Barreau A, Rohatgi R Nature communications 31653829 Nat Commun 2019 Oct 25 https://www.ncbi.nlm.nih.gov/pubmed/31653829
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G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog. Pusapati GV, Kong JH, Patel BB, Gouti M, Sagner A, Sircar R, Luchetti G, Ingham PW, Briscoe J, Rohatgi R Science signaling 29438014 Sci Signal 2018 Feb 6 https://www.ncbi.nlm.nih.gov/pubmed/29438014
Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1. Dubey R, Lebensohn AM, Bahrami-Nejad Z, Marceau C, Champion M, Gevaert O, Sikic BI, Carette JE, Rohatgi R Cancer research 27503929 Cancer Res 2016 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/27503929
Measuring Expression Levels of Endogenous Gli Genes by Immunoblotting and Real-Time PCR. Niewiadomski P, Rohatgi R Methods in molecular biology (Clifton, N.J.) 26179041 Methods Mol Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26179041
Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry. Ahrends R, Niewiadomski P, Teruel MN, Rohatgi R Methods in molecular biology (Clifton, N.J.) 26179043 Methods Mol Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26179043
In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes. Schmidt HB, Rohatgi R Cell reports 27452472 Cell Rep 2016 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/27452472
R-spondins can potentiate WNT signaling without LGRs. Lebensohn AM, Rohatgi R eLife 29405118 Elife 2018 Feb 6 https://www.ncbi.nlm.nih.gov/pubmed/29405118
CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog. Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R Developmental cell 29290584 Dev Cell 2018 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/29290584
Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. Kong JH, Yang L, Dessaud E, Chuang K, Moore DM, Rohatgi R, Briscoe J, Novitch BG Developmental cell 25936505 Dev Cell 2015 May 26 https://www.ncbi.nlm.nih.gov/pubmed/25936505
G-protein-coupled receptors, Hedgehog signaling and primary cilia. Mukhopadhyay S, Rohatgi R Seminars in cell & developmental biology 24845016 Semin Cell Dev Biol 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/24845016
TDP-43 α-helical structure tunes liquid-liquid phase separation and function. Conicella AE, Dignon GL, Zerze GH, Schmidt HB, D'Ordine AM, Kim YC, Rohatgi R, Ayala YM, Mittal J, Fawzi NL Proceedings of the National Academy of Sciences of the United States of America 32132204 Proc Natl Acad Sci U S A 2020 Mar 17 https://www.ncbi.nlm.nih.gov/pubmed/32132204
Multiple ligand binding sites regulate the Hedgehog signal transducer Smoothened in vertebrates. Byrne EF, Luchetti G, Rohatgi R, Siebold C Current opinion in cell biology 29268141 Curr Opin Cell Biol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29268141
CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog. Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R Developmental cell 29401421 Dev Cell 2018 Jan 22 https://www.ncbi.nlm.nih.gov/pubmed/29401421
Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. Lebensohn AM, Dubey R, Neitzel LR, Tacchelly-Benites O, Yang E, Marceau CD, Davis EM, Patel BB, Bahrami-Nejad Z, Travaglini KJ, Ahmed Y, Lee E, Carette JE, Rohatgi R eLife 27996937 Elife 2016 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/27996937
Cholesterol accessibility at the ciliary membrane controls hedgehog signaling. Kinnebrew M, Iverson EJ, Patel BB, Pusapati GV, Kong JH, Johnson KA, Luchetti G, Eckert KM, McDonald JG, Covey DF, Siebold C, Radhakrishnan A, Rohatgi R eLife 31657721 Elife 2019 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/31657721
Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision. Phua SC, Chiba S, Suzuki M, Su E, Roberson EC, Pusapati GV, Schurmans S, Setou M, Rohatgi R, Reiter JF, Ikegami K, Inoue T Cell 28086093 Cell 2017 Jan 12 https://www.ncbi.nlm.nih.gov/pubmed/28086093
A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing. Wang A, Conicella AE, Schmidt HB, Martin EW, Rhoads SN, Reeb AN, Nourse A, Ramirez Montero D, Ryan VH, Rohatgi R, Shewmaker F, Naik MT, Mittag T, Ayala YM, Fawzi NL The EMBO journal 29438978 EMBO J 2018 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/29438978
Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens. Patel BB, Lebensohn AM, Pusapati GV, Carette JE, Salzman J, Rohatgi R PloS one 30695034 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/30695034
Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling. Hong SR, Wang CL, Huang YS, Chang YC, Chang YC, Pusapati GV, Lin CY, Hsu N, Cheng HC, Chiang YC, Huang WE, Shaner NC, Rohatgi R, Inoue T, Lin YC Nature communications 29712905 Nat Commun 2018 Apr 30 https://www.ncbi.nlm.nih.gov/pubmed/29712905
Rapid Screening of Gli2/3 Mutants Using the Flp-In System. Niewiadomski P, Rohatgi R Methods in molecular biology (Clifton, N.J.) 26179044 Methods Mol Biol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26179044
Photoactivatable protein labeling by singlet oxygen mediated reactions. To TL, Medzihradszky KF, Burlingame AL, DeGrado WF, Jo H, Shu X Bioorganic & medicinal chemistry letters 27220724 Bioorg Med Chem Lett 2016 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/27220724
Precision Optogenetic Tool for Selective Single- and Multiple-Cell Ablation in a Live Animal Model System. Makhijani K, To TL, Ruiz-González R, Lafaye C, Royant A, Shu X Cell chemical biology 28065655 Cell Chem Biol 2017 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/28065655
Singlet oxygen triplet energy transfer-based imaging technology for mapping protein-protein proximity in intact cells. To TL, Fadul MJ, Shu X Nature communications 24905026 Nat Commun 2014 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/24905026
Dynamic Imaging of Small Molecule Induced Protein-Protein Interactions in Living Cells with a Fluorophore Phase Transition Based Approach. Chung CI, Zhang Q, Shu X Analytical chemistry 30431263 Anal Chem 2018 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/30431263
Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. Zhang Q, Huang H, Zhang L, Wu R, Chung CI, Zhang SQ, Torra J, Schepis A, Coughlin SR, Kornberg TB, Shu X Molecular cell 29307513 Mol Cell 2018 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/29307513
A rapid fluorogenic GPCR-β-arrestin interaction assay. Zhang Q, Zheng YW, Coughlin SR, Shu X Protein science : a publication of the Protein Society 29411438 Protein Sci 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29411438
Structure-guided design of a reversible fluorogenic reporter of protein-protein interactions. To TL, Zhang Q, Shu X Protein science : a publication of the Protein Society 26690964 Protein Sci 2016 Mar https://www.ncbi.nlm.nih.gov/pubmed/26690964
Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network. Culyba MJ, Kubiak JM, Mo CY, Goulian M, Kohli RM PLoS genetics 29856734 PLoS Genet 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29856734
Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response. Selwood T, Larsen BJ, Mo CY, Culyba MJ, Hostetler ZM, Kohli RM, Reitz AB, Baugh SDP Frontiers in microbiology 30619111 Front Microbiol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30619111
Systematically Altering Bacterial SOS Activity under Stress Reveals Therapeutic Strategies for Potentiating Antibiotics. Mo CY, Manning SA, Roggiani M, Culyba MJ, Samuels AN, Sniegowski PD, Goulian M, Kohli RM mSphere 27536734 mSphere 2016 Jul-Aug https://www.ncbi.nlm.nih.gov/pubmed/27536734
A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage. Kubiak JM, Culyba MJ, Liu MY, Mo CY, Goulian M, Kohli RM ACS synthetic biology 28826208 ACS Synth Biol 2017 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/28826208
Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection. Sungwienwong I, Hostetler ZM, Blizzard RJ, Porter JJ, Driggers CM, Mbengi LZ, Villegas JA, Speight LC, Saven JG, Perona JJ, Kohli RM, Mehl RA, Petersson EJ Organic & biomolecular chemistry 28397914 Org Biomol Chem 2017 May 3 https://www.ncbi.nlm.nih.gov/pubmed/28397914
Specificity determinants for autoproteolysis of LexA, a key regulator of bacterial SOS mutagenesis. Mo CY, Birdwell LD, Kohli RM Biochemistry 24779472 Biochemistry 2014 May 20 https://www.ncbi.nlm.nih.gov/pubmed/24779472
Targets for Combating the Evolution of Acquired Antibiotic Resistance. Culyba MJ, Mo CY, Kohli RM Biochemistry 26016604 Biochemistry 2015 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/26016604
DNA Methyltransferases Demonstrate Reduced Activity against Arabinosylcytosine: Implications for Epigenetic Instability in Acute Myeloid Leukemia. Nabel CS, DeNizio JE, Carroll M, Kohli RM Biochemistry 28394581 Biochemistry 2017 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/28394581
Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership. Mo CY, Culyba MJ, Selwood T, Kubiak JM, Hostetler ZM, Jurewicz AJ, Keller PM, Pope AJ, Quinn A, Schneck J, Widdowson KL, Kohli RM ACS infectious diseases 29275629 ACS Infect Dis 2018 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/29275629
Simple and versatile imaging of genomic loci in live mammalian cells and early pre-implantation embryos using CAS-LiveFISH. Geng Y, Pertsinidis A Scientific reports 34108610 Sci Rep 2021 Jun 9 https://www.ncbi.nlm.nih.gov/pubmed/34108610
Single-Molecule Real-Time 3D Imaging of the Transcription Cycle by Modulation Interferometry. Wang G, Hauver J, Thomas Z, Darst SA, Pertsinidis A Cell 27984731 Cell 2016 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/27984731
Volumetric interferometric lattice light-sheet imaging. Cao B, Coelho S, Li J, Wang G, Pertsinidis A Nature biotechnology 34635835 Nat Biotechnol 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34635835
Topoisomerase III Acts at the Replication Fork To Remove Precatenanes. Lee CM, Wang G, Pertsinidis A, Marians KJ Journal of bacteriology 30617245 J Bacteriol 2019 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/30617245
Single-gene imaging links genome topology, promoter-enhancer communication and transcription control. Li J, Hsu A, Hua Y, Wang G, Cheng L, Ochiai H, Yamamoto T, Pertsinidis A Nature structural & molecular biology 32958948 Nat Struct Mol Biol 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/32958948
A Single-Molecule Surface-Based Platform to Detect the Assembly and Function of the Human RNA Polymerase II Transcription Machinery. Park SR, Hauver J, Zhang Y, Revyakin A, Coleman RA, Tjian R, Chu S, Pertsinidis A Structure (London, England : 1993) 32763141 Structure 2020 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/32763141
Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells. Li J, Dong A, Saydaminova K, Chang H, Wang G, Ochiai H, Yamamoto T, Pertsinidis A Cell 31155237 Cell 2019 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/31155237
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Metabolic inflexibility promotes mitochondrial health during liver regeneration. Wang X, Menezes CJ, Jia Y, Xiao Y, Venigalla SSK, Cai F, Hsieh MH, Gu W, Du L, Sudderth J, Kim D, Shelton SD, Llamas CB, Lin YH, Zhu M, Merchant S, Bezwada D, Kelekar S, Zacharias LG, Mathews TP, Hoxhaj G, Wynn RM, Tambar UK, DeBerardinis RJ, Zhu H, Mishra P Science (New York, N.Y.) 38870309 Science 2024 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/38870309
Bioorthogonal Retro-Cope Elimination Reaction of N,N-Dialkylhydroxylamines and Strained Alkynes. Kang D, Kim J Journal of the American Chemical Society 33829777 J Am Chem Soc 2021 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/33829777
Enamine N-oxides: Design, Synthesis, and Function in Bioorthogonal Reactions. Kang D, Kim J Synlett : accounts and rapid communications in synthetic organic chemistry 38947226 Synlett 2024 Jan https://www.ncbi.nlm.nih.gov/pubmed/38947226
Bioorthogonal Click and Release: A General, Rapid, Chemically Revertible Bioconjugation Strategy Employing Enamine N-oxides. Kang D, Lee S, Kim J Chem 36176744 Chem 2022 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/36176744
Enamine N-Oxides: Synthesis and Application to Hypoxia-Responsive Prodrugs and Imaging Agents. Kang D, Cheung ST, Wong-Rolle A, Kim J ACS central science 34056093 ACS Cent Sci 2021 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/34056093
Bioorthogonally activated reactive species for target identification. Siriwongsup S, Schmoker AM, Ficarro SB, Marto JA, Kim J Chem 38617077 Chem 2024 Apr 11 https://www.ncbi.nlm.nih.gov/pubmed/38617077
Bioorthogonal Hydroamination of Push-Pull-Activated Linear Alkynes. Kang D, Cheung ST, Kim J Angewandte Chemie (International ed. in English) 34019705 Angew Chem Int Ed Engl 2021 Jul 26 https://www.ncbi.nlm.nih.gov/pubmed/34019705
Synthesis of push-pull-activated ynol ethers and their evaluation in the bioorthogonal hydroamination reaction. Kang D, Wahl C, Kim J Organic & biomolecular chemistry 36367436 Org Biomol Chem 2022 Nov 30 https://www.ncbi.nlm.nih.gov/pubmed/36367436
Tissue clearing and its applications in neuroscience. Ueda HR, Ertürk A, Chung K, Gradinaru V, Chédotal A, Tomancak P, Keller PJ Nature reviews. Neuroscience 31896771 Nat Rev Neurosci 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31896771
Protection of tissue physicochemical properties using polyfunctional crosslinkers. Park YG, Sohn CH, Chen R, McCue M, Yun DH, Drummond GT, Ku T, Evans NB, Oak HC, Trieu W, Choi H, Jin X, Lilascharoen V, Wang J, Truttmann MC, Qi HW, Ploegh HL, Golub TR, Chen SC, Frosch MP, Kulik HJ, Lim BK, Chung K Nature biotechnology 30556815 Nat Biotechnol 2018 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/30556815
Depolarization signatures map gold nanorods within biological tissue. Lippok N, Villiger M, Albanese A, Meijer EFJ, Chung K, Padera TP, Bhatia SN, Bouma BE Nature photonics 29201136 Nat Photonics 2017 https://www.ncbi.nlm.nih.gov/pubmed/29201136
Integrated platform for multiscale molecular imaging and phenotyping of the human brain. Park J, Wang J, Guan W, Gjesteby LA, Pollack D, Kamentsky L, Evans NB, Stirman J, Gu X, Zhao C, Marx S, Kim ME, Choi SW, Snyder M, Chavez D, Su-Arcaro C, Tian Y, Park CS, Zhang Q, Yun DH, Moukheiber M, Feng G, Yang XW, Keene CD, Hof PR, Ghosh SS, Frosch MP, Brattain LJ, Chung K Science (New York, N.Y.) 38870291 Science 2024 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/38870291
Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems. Murray E, Cho JH, Goodwin D, Ku T, Swaney J, Kim SY, Choi H, Park YG, Park JY, Hubbert A, McCue M, Vassallo S, Bakh N, Frosch MP, Wedeen VJ, Seung HS, Chung K Cell 26638076 Cell 2015 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/26638076
Basic principles of hydrogel-based tissue transformation technologies and their applications. Choi SW, Guan W, Chung K Cell 34358468 Cell 2021 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/34358468
Elasticizing tissues for reversible shape transformation and accelerated molecular labeling. Ku T, Guan W, Evans NB, Sohn CH, Albanese A, Kim JG, Frosch MP, Chung K Nature methods 32424271 Nat Methods 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32424271
Label-free volumetric optical imaging of intact murine brains. Ren J, Choi H, Chung K, Bouma BE Scientific reports 28401897 Sci Rep 2017 Apr 12 https://www.ncbi.nlm.nih.gov/pubmed/28401897
Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions. Roy DS, Park YG, Kim ME, Zhang Y, Ogawa SK, DiNapoli N, Gu X, Cho JH, Choi H, Kamentsky L, Martin J, Mosto O, Aida T, Chung K, Tonegawa S Nature communications 35379803 Nat Commun 2022 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/35379803
Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues. Ku T, Swaney J, Park JY, Albanese A, Murray E, Cho JH, Park YG, Mangena V, Chen J, Chung K Nature biotechnology 27454740 Nat Biotechnol 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/27454740
Multiscale 3D phenotyping of human cerebral organoids. Albanese A, Swaney JM, Yun DH, Evans NB, Antonucci JM, Velasco S, Sohn CH, Arlotta P, Gehrke L, Chung K Scientific reports 33293587 Sci Rep 2020 Dec 8 https://www.ncbi.nlm.nih.gov/pubmed/33293587
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease. Stevens KR, Scull MA, Ramanan V, Fortin CL, Chaturvedi RR, Knouse KA, Xiao JW, Fung C, Mirabella T, Chen AX, McCue MG, Yang MT, Fleming HE, Chung K, de Jong YP, Chen CS, Rice CM, Bhatia SN Science translational medicine 28724577 Sci Transl Med 2017 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/28724577
Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy. Mano T, Albanese A, Dodt HU, Erturk A, Gradinaru V, Treweek JB, Miyawaki A, Chung K, Ueda HR The Journal of neuroscience : the official journal of the Society for Neuroscience 30381424 J Neurosci 2018 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/30381424
Npas4 Is a Critical Regulator of Learning-Induced Plasticity at Mossy Fiber-CA3 Synapses during Contextual Memory Formation. Weng FJ, Garcia RI, Lutzu S, Alviña K, Zhang Y, Dushko M, Ku T, Zemoura K, Rich D, Garcia-Dominguez D, Hung M, Yelhekar TD, Sørensen AT, Xu W, Chung K, Castillo PE, Lin Y Neuron 29429933 Neuron 2018 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/29429933
Self-organized developmental patterning and differentiation in cerebral organoids. Renner M, Lancaster MA, Bian S, Choi H, Ku T, Peer A, Chung K, Knoblich JA The EMBO journal 28283582 EMBO J 2017 May 15 https://www.ncbi.nlm.nih.gov/pubmed/28283582
Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Martorell AJ, Paulson AL, Suk HJ, Abdurrob F, Drummond GT, Guan W, Young JZ, Kim DN, Kritskiy O, Barker SJ, Mangena V, Prince SM, Brown EN, Chung K, Boyden ES, Singer AC, Tsai LH Cell 30879788 Cell 2019 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/30879788
TISSUE CLEARING. Richardson DS, Guan W, Matsumoto K, Pan C, Chung K, Ertürk A, Ueda HR, Lichtman JW Nature reviews. Methods primers 35128463 Nat Rev Methods Primers 2021 https://www.ncbi.nlm.nih.gov/pubmed/35128463
Recent advances in simultaneous analysis of bisphenol A and its conjugates in human matrices: Exposure biomarker perspectives. Andra SS, Austin C, Yang J, Patel D, Arora M The Science of the total environment 27586167 Sci Total Environ 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27586167
A multimodal imaging workflow to visualize metal mixtures in the human placenta and explore colocalization with biological response markers. Niedzwiecki MM, Austin C, Remark R, Merad M, Gnjatic S, Estrada-Gutierrez G, Espejel-Nuñez A, Borboa-Olivares H, Guzman-Huerta M, Wright RJ, Wright RO, Arora M Metallomics : integrated biometal science 26987553 Metallomics 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26987553
Comparison of multiple X-ray fluorescence techniques for elemental analysis of particulate matter collected on air filters. Bilo F, Borgese L, Wambui A, Assi A, Zacco A, Federici S, Eichert DM, Tsuji K, Lucchini RG, Placidi D, Bontempi E, Depero LE Journal of aerosol science 30662085 J Aerosol Sci 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/30662085
Elemental signatures of Australopithecus africanus teeth reveal seasonal dietary stress. Joannes-Boyau R, Adams JW, Austin C, Arora M, Moffat I, Herries AIR, Tonge MP, Benazzi S, Evans AR, Kullmer O, Wroe S, Dosseto A, Fiorenza L Nature 31308534 Nature 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31308534
Bayesian varying coefficient kernel machine regression to assess neurodevelopmental trajectories associated with exposure to complex mixtures. Liu SH, Bobb JF, Claus Henn B, Gennings C, Schnaas L, Tellez-Rojo M, Bellinger D, Arora M, Wright RO, Coull BA Statistics in medicine 30277584 Stat Med 2018 Dec 30 https://www.ncbi.nlm.nih.gov/pubmed/30277584
Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth. Wahlberg K, Arora M, Curtin A, Curtin P, Wright RO, Smith DR, Lucchini RG, Broberg K, Austin C Neurotoxicology 28917719 Neurotoxicology 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/28917719
Stress exposure histories revealed by biochemical changes along accentuated lines in teeth. Austin C, Kumar P, Carter EA, Lee J, Smith TM, Hinde K, Arora M, Lay PA Chemosphere 37054846 Chemosphere 2023 Jul https://www.ncbi.nlm.nih.gov/pubmed/37054846
Sex differences in sensitivity to prenatal and early childhood manganese exposure on neuromotor function in adolescents. Chiu YM, Claus Henn B, Hsu HL, Pendo MP, Coull BA, Austin C, Cagna G, Fedrighi C, Placidi D, Smith DR, Wright RO, Lucchini RG, Arora M Environmental research 28858760 Environ Res 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28858760
Dentine biomarkers of prenatal and early childhood exposure to manganese, zinc and lead and childhood behavior. Horton MK, Hsu L, Claus Henn B, Margolis A, Austin C, Svensson K, Schnaas L, Gennings C, Hu H, Wright R, Rojo MMT, Arora M Environment international 30205321 Environ Int 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30205321
Near-Infrared Intraoperative Chemiluminescence Imaging. Büchel GE, Carney B, Shaffer TM, Tang J, Austin C, Arora M, Zeglis BM, Grimm J, Eppinger J, Reiner T ChemMedChem 27471800 ChemMedChem 2016 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/27471800
Fetal and postnatal metal dysregulation in autism. Arora M, Reichenberg A, Willfors C, Austin C, Gennings C, Berggren S, Lichtenstein P, Anckarsäter H, Tammimies K, Bölte S Nature communications 28569757 Nat Commun 2017 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/28569757
Is poor oral health a risk marker for incident cardiovascular disease hospitalisation and all-cause mortality? Findings from 172 630 participants from the prospective 45 and Up Study. Joshy G, Arora M, Korda RJ, Chalmers J, Banks E BMJ open 27577588 BMJ Open 2016 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/27577588
Manganese transporter genetics and sex modify the association between environmental manganese exposure and neurobehavioral outcomes in children. Broberg K, Taj T, Guazzetti S, Peli M, Cagna G, Pineda D, Placidi D, Wright RO, Smith DR, Lucchini RG, Wahlberg K Environment international 31233999 Environ Int 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31233999
The tooth exposome in children's health research. Andra SS, Austin C, Arora M Current opinion in pediatrics 26859286 Curr Opin Pediatr 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26859286
Uncovering neurodevelopmental windows of susceptibility to manganese exposure using dentine microspatial analyses. Claus Henn B, Austin C, Coull BA, Schnaas L, Gennings C, Horton MK, Hernández-Ávila M, Hu H, Téllez-Rojo MM, Wright RO, Arora M Environmental research 29247915 Environ Res 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29247915
Critical windows of susceptibility in the association between manganese and neurocognition in Italian adolescents living near ferro-manganese industry. Bauer JA, White RF, Coull BA, Austin C, Oppini M, Zoni S, Fedrighi C, Cagna G, Placidi D, Guazzetti S, Yang Q, Bellinger DC, Webster TF, Wright RO, Smith D, Horton M, Lucchini RG, Arora M, Claus Henn B Neurotoxicology 34478771 Neurotoxicology 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34478771
In utero metal exposures measured in deciduous teeth and birth outcomes in a racially-diverse urban cohort. Cassidy-Bushrow AE, Wu KH, Sitarik AR, Park SK, Bielak LF, Austin C, Gennings C, Curtin P, Johnson CC, Arora M Environmental research 30735952 Environ Res 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/30735952
Exposure to environmental chemical mixtures is associated with nasal colonization by Staphylococcus aureus: NHANES 2001-2004. Eggers S, Gennings C, Malecki KMC, Safdar N, Arora M Environmental research 32771801 Environ Res 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/32771801
Prenatal and postnatal manganese teeth levels and neurodevelopment at 7, 9, and 10.5 years in the CHAMACOS cohort. Mora AM, Arora M, Harley KG, Kogut K, Parra K, Hernández-Bonilla D, Gunier RB, Bradman A, Smith DR, Eskenazi B Environment international 26209874 Environ Int 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26209874
Tooth matrix analysis for biomonitoring of organic chemical exposure: Current status, challenges, and opportunities. Andra SS, Austin C, Arora M Environmental research 26219084 Environ Res 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26219084
Reconstructing pre-natal and early childhood exposure to multi-class organic chemicals using teeth: Towards a retrospective temporal exposome. Andra SS, Austin C, Wright RO, Arora M Environment international 26134987 Environ Int 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26134987
Manganese in teeth and neurodevelopment in young Mexican-American children. Gunier RB, Arora M, Jerrett M, Bradman A, Harley KG, Mora AM, Kogut K, Hubbard A, Austin C, Holland N, Eskenazi B Environmental research 26381693 Environ Res 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26381693
Recurrence quantification analysis to characterize cyclical components of environmental elemental exposures during fetal and postnatal development. Curtin P, Curtin A, Austin C, Gennings C, Tammimies K, Bölte S, Arora M PloS one 29112980 PLoS One 2017 https://www.ncbi.nlm.nih.gov/pubmed/29112980
Uncovering system-specific stress signatures in primate teeth with multimodal imaging. Austin C, Smith TM, Farahani RM, Hinde K, Carter EA, Lee J, Lay PA, Kennedy BJ, Sarrafpour B, Wright RJ, Wright RO, Arora M Scientific reports 26727334 Sci Rep 2016 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/26727334
Cyclical nursing patterns in wild orangutans. Smith TM, Austin C, Hinde K, Vogel ER, Arora M Science advances 28560319 Sci Adv 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28560319
Extending the Distributed Lag Model framework to handle chemical mixtures. Bello GA, Arora M, Austin C, Horton MK, Wright RO, Gennings C Environmental research 28371754 Environ Res 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28371754
Burden of higher lead exposure in African-Americans starts in utero and persists into childhood. Cassidy-Bushrow AE, Sitarik AR, Havstad S, Park SK, Bielak LF, Austin C, Johnson CC, Arora M Environment international 28886415 Environ Int 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28886415
Manganese in teeth and neurobehavior: Sex-specific windows of susceptibility. Bauer JA, Claus Henn B, Austin C, Zoni S, Fedrighi C, Cagna G, Placidi D, White RF, Yang Q, Coull BA, Smith D, Lucchini RG, Wright RO, Arora M Environment international 28941415 Environ Int 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28941415
Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity. Morishita H, Arora M Trends in neurosciences 28038829 Trends Neurosci 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/28038829
Tooth manganese as a biomarker of exposure and body burden in rats. Austin C, Richardson C, Smith D, Arora M Environmental research 28279842 Environ Res 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28279842
Wintertime stress, nursing, and lead exposure in Neanderthal children. Smith TM, Austin C, Green DR, Joannes-Boyau R, Bailey S, Dumitriu D, Fallon S, Grün R, James HF, Moncel MH, Williams IS, Wood R, Arora M Science advances 30402544 Sci Adv 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30402544
Dynamical properties of elemental metabolism distinguish attention deficit hyperactivity disorder from autism spectrum disorder. Austin C, Curtin P, Curtin A, Gennings C, Arora M, Tammimies K, Isaksson J, Willfors C, Bölte S Translational psychiatry 31551411 Transl Psychiatry 2019 Sep 25 https://www.ncbi.nlm.nih.gov/pubmed/31551411
Modeling the health effects of time-varying complex environmental mixtures: Mean field variational Bayes for lagged kernel machine regression. Liu SH, Bobb JF, Claus Henn B, Schnaas L, Tellez-Rojo MM, Gennings C, Arora M, Wright RO, Coull BA, Wand MP Environmetrics 30686915 Environmetrics 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/30686915
Cross-sectional study of the association between serum perfluorinated alkyl acid concentrations and dental caries among US adolescents (NHANES 1999-2012). Puttige Ramesh N, Arora M, Braun JM BMJ open 30782897 BMJ Open 2019 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/30782897
Dynamical features in fetal and postnatal zinc-copper metabolic cycles predict the emergence of autism spectrum disorder. Curtin P, Austin C, Curtin A, Gennings C, Arora M, (for the Emergent Dynamical Systems Group), Tammimies K, Willfors C, Berggren S, Siper P, Rai D, Meyering K, Kolevzon A, Mollon J, David AS, Lewis G, Zammit S, Heilbrun L, Palmer RF, Wright RO, Bölte S, Reichenberg A Science advances 29854952 Sci Adv 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29854952
Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice. Morris-Schaffer K, Sobolewski M, Allen JL, Marvin E, Yee M, Arora M, O'Reilly MA, Cory-Slechta DA Neurotoxicology 29920326 Neurotoxicology 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29920326
New Research Strategy for Measuring Pre- and Postnatal Metal Dysregulation in Psychotic Disorders. Velthorst E, Smith L, Bello G, Austin C, Gennings C, Modabbernia A, Franke N, Frangou S, Wright R, de Haan L, Reichenberg A, Arora M Schizophrenia bulletin 28981868 Schizophr Bull 2017 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/28981868
Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis. Curtin P, Austin C, Curtin A, Gennings C, Figueroa-Romero C, Mikhail KA, Botero TM, Goutman SA, Feldman EL, Arora M PLoS computational biology 32294079 PLoS Comput Biol 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32294079
Multielemental bioimaging of tissues in children's environmental health research. Austinc C, Niedzwiecki MM, Arora M Current opinion in pediatrics 26845145 Curr Opin Pediatr 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26845145
Early-life dentine manganese concentrations and intrinsic functional brain connectivity in adolescents: A pilot study. de Water E, Papazaharias DM, Ambrosi C, Mascaro L, Iannilli E, Gasparotti R, Lucchini RG, Austin C, Arora M, Tang CY, Smith DR, Wright RO, Horton MK PloS one 31412061 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/31412061
A Perspective on Crowdsourcing and Human-in-the-Loop Workflows in Precision Health. Washington P Journal of medical Internet research 38602750 J Med Internet Res 2024 Apr 11 https://www.ncbi.nlm.nih.gov/pubmed/38602750
Audio-Based Emotion Recognition Using Self-Supervised Learning on an Engineered Feature Space. Nimitsurachat P, Washington P AI (Basel, Switzerland) 38715564 AI (Basel) 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38715564
Digitally Diagnosing Multiple Developmental Delays Using Crowdsourcing Fused With Machine Learning: Protocol for a Human-in-the-Loop Machine Learning Study. Jaiswal A, Kruiper R, Rasool A, Nandkeolyar A, Wall DP, Washington P JMIR research protocols 38329783 JMIR Res Protoc 2024 Feb 8 https://www.ncbi.nlm.nih.gov/pubmed/38329783
Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design. Li Y, Li N, Liu W, Prominski A, Kang S, Dai Y, Liu Y, Hu H, Wai S, Dai S, Cheng Z, Su Q, Cheng P, Wei C, Jin L, Hubbell JA, Tian B, Wang S Nature communications 37495580 Nat Commun 2023 Jul 26 https://www.ncbi.nlm.nih.gov/pubmed/37495580
Bioadhesive polymer semiconductors and transistors for intimate biointerfaces. Li N, Li Y, Cheng Z, Liu Y, Dai Y, Kang S, Li S, Shan N, Wai S, Ziaja A, Wang Y, Strzalka J, Liu W, Zhang C, Gu X, Hubbell JA, Tian B, Wang S Science (New York, N.Y.) 37561870 Science 2023 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/37561870
Soft mechanical sensors for wearable and implantable applications. Papani R, Li Y, Wang S Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 38723798 Wiley Interdiscip Rev Nanomed Nanobiotechnol 2024 May-Jun https://www.ncbi.nlm.nih.gov/pubmed/38723798
A Neuromorphic Brain Interface based on RRAM Crossbar Arrays for High Throughput Real-time Spike Sorting. Shi Y, Ananthakrishnan A, Oh S, Liu X, Hota G, Cauwenberghs G, Kuzum D IEEE transactions on electron devices 37168652 IEEE Trans Electron Devices 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/37168652
Energy-efficient Mott activation neuron for full-hardware implementation of neural networks. Oh S, Shi Y, Del Valle J, Salev P, Lu Y, Huang Z, Kalcheim Y, Schuller IK, Kuzum D Nature nanotechnology 33737724 Nat Nanotechnol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33737724
Multimodal neural recordings with Neuro-FITM uncover diverse patterns of cortical-hippocampal interactions. Liu X, Ren C, Lu Y, Liu Y, Kim JH, Leutgeb S, Komiyama T, Kuzum D Nature neuroscience 33875893 Nat Neurosci 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33875893
Evaluation of Durability of Transparent Graphene Electrodes Fabricated on Different Flexible Substrates for Chronic In Vivo Experiments. Ding D, Lu Y, Zhao R, Liu X, De-Eknamkul C, Ren C, Mehrsa A, Komiyama T, Kuzum D IEEE transactions on bio-medical engineering 32191878 IEEE Trans Biomed Eng 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/32191878
E-Cannula reveals anatomical diversity in sharp-wave ripples as a driver for the recruitment of distinct hippocampal assemblies. Liu X, Terada S, Ramezani M, Kim JH, Lu Y, Grosmark A, Losonczy A, Kuzum D Cell reports 36198271 Cell Rep 2022 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/36198271
Decoding of cortex-wide brain activity from local recordings of neural potentials. Liu X, Ren C, Huang Z, Wilson M, Kim JH, Lu Y, Ramezani M, Komiyama T, Kuzum D Journal of neural engineering 34706356 J Neural Eng 2021 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/34706356
High-density transparent graphene arrays for predicting cellular calcium activity at depth from surface potential recordings. Ramezani M, Kim JH, Liu X, Ren C, Alothman A, De-Eknamkul C, Wilson MN, Cubukcu E, Gilja V, Komiyama T, Kuzum D Nature nanotechnology 38212523 Nat Nanotechnol 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38212523
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex. Wilson MN, Thunemann M, Liu X, Lu Y, Puppo F, Adams JW, Kim JH, Ramezani M, Pizzo DP, Djurovic S, Andreassen OA, Mansour AA, Gage FH, Muotri AR, Devor A, Kuzum D Nature communications 36572698 Nat Commun 2022 Dec 26 https://www.ncbi.nlm.nih.gov/pubmed/36572698
Electrochemical and electrophysiological considerations for clinical high channel count neural interfaces. Vatsyayan R, Lee J, Bourhis AM, Tchoe Y, Cleary DR, Tonsfeldt KJ, Lee K, Montgomery-Walsh R, Paulk AC, U HS, Cash SS, Dayeh SA MRS bulletin 37476355 MRS Bull 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37476355
Intraoperative application and early experience with novel high-resolution, high-channel-count thin-film electrodes for human microelectrocorticography. Tan H, Paulk AC, Stedelin B, Cleary DR, Nerison C, Tchoe Y, Brown EC, Bourhis A, Russman S, Lee J, Tonsfeldt KJ, Yang JC, Oh H, Ro YG, Lee K, Ganji M, Galton I, Siler D, Han SJ, Collins KL, Ben-Haim S, Halgren E, Cash SS, Dayeh S, Raslan AM Journal of neurosurgery 37874692 J Neurosurg 2024 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/37874692
An Analytical Model for Dual Gate Piezoelectrically Sensitive ZnO Thin Film Transistors. Oh H, Dayeh SA Advanced materials technologies 34485683 Adv Mater Technol 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34485683
Surface-Grafted Biocompatible Polymer Conductors for Stable and Compliant Electrodes for Brain Interfaces. Blau R, Russman SM, Qie Y, Shipley W, Lim A, Chen AX, Nyayachavadi A, Ah L, Abdal A, Esparza GL, Edmunds SJ, Vatsyayan R, Dunfield SP, Halder M, Jokerst JV, Fenning DP, Tao AR, Dayeh SA, Lipomi DJ Advanced healthcare materials 39011811 Adv Healthc Mater 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/39011811
Human brain mapping with multithousand-channel PtNRGrids resolves spatiotemporal dynamics. Tchoe Y, Bourhis AM, Cleary DR, Stedelin B, Lee J, Tonsfeldt KJ, Brown EC, Siler DA, Paulk AC, Yang JC, Oh H, Ro YG, Lee K, Russman SM, Ganji M, Galton I, Ben-Haim S, Raslan AM, Dayeh SA Science translational medicine 35044788 Sci Transl Med 2022 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/35044788
Microscale Physiological Events on the Human Cortical Surface. Paulk AC, Yang JC, Cleary DR, Soper DJ, Halgren M, O'Donnell AR, Lee SH, Ganji M, Ro YG, Oh H, Hossain L, Lee J, Tchoe Y, Rogers N, Kiliç K, Ryu SB, Lee SW, Hermiz J, Gilja V, Ulbert I, Fabó D, Thesen T, Doyle WK, Devinsky O, Madsen JR, Schomer DL, Eskandar EN, Lee JW, Maus D, Devor A, Fried SI, Jones PS, Nahed BV, Ben-Haim S, Bick SK, Richardson RM, Raslan AM, Siler DA, Cahill DP, Williams ZM, Cosgrove GR, Dayeh SA, Cash SS Cerebral cortex (New York, N.Y. : 1991) 33749727 Cereb Cortex 2021 Jul 5 https://www.ncbi.nlm.nih.gov/pubmed/33749727
Scalable tactile sensor arrays on flexible substrates with high spatiotemporal resolution enabling slip and grip for closed-loop robotics. Oh H, Yi GC, Yip M, Dayeh SA Science advances 33188031 Sci Adv 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/33188031
Selective Formation of Porous Pt Nanorods for Highly Electrochemically Efficient Neural Electrode Interfaces. Ganji M, Paulk AC, Yang JC, Vahidi NW, Lee SH, Liu R, Hossain L, Arneodo EM, Thunemann M, Shigyo M, Tanaka A, Ryu SB, Lee SW, Tchoe Y, Marsala M, Devor A, Cleary DR, Martin JR, Oh H, Gilja V, Gentner TQ, Fried SI, Halgren E, Cash SS, Dayeh SA Nano letters 31369283 Nano Lett 2019 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/31369283
Electrochemical safety limits for clinical stimulation investigated using depth and strip electrodes in the pig brain. Vatsyayan R, Cleary D, Martin JR, Halgren E, Dayeh SA Journal of neural engineering 34015769 J Neural Eng 2021 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/34015769
Ultra-Sharp Nanowire Arrays Natively Permeate, Record, and Stimulate Intracellular Activity in Neuronal and Cardiac Networks. Liu R, Lee J, Tchoe Y, Pre D, Bourhis AM, D'Antonio-Chronowska A, Robin G, Lee SH, Ro YG, Vatsyayan R, Tonsfeldt KJ, Hossain LA, Phipps ML, Yoo J, Nogan J, Martinez JS, Frazer KA, Bang AG, Dayeh SA Advanced functional materials 35603230 Adv Funct Mater 2022 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/35603230
Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation. Gonzalez G, Nelson AC, Holman AR, Whitehead AJ, LaMontagne E, Lian R, Vatsyayan R, Dayeh SA, Engler AJ Biomaterials 37898021 Biomaterials 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37898021
The Brain Electroencephalogram Microdisplay for Precision Neurosurgery. Tchoe Y, Wu T, U HS, Roth DM, Kim D, Lee J, Cleary DR, Pizarro P, Tonsfeldt KJ, Lee K, Chen PC, Bourhis AM, Galton I, Coughlin B, Yang JC, Paulk AC, Halgren E, Cash SS, Dayeh SA bioRxiv : the preprint server for biology 37503216 bioRxiv 2023 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/37503216
Flexible, scalable, high channel count stereo-electrode for recording in the human brain. Lee K, Paulk AC, Ro YG, Cleary DR, Tonsfeldt KJ, Kfir Y, Pezaris JS, Tchoe Y, Lee J, Bourhis AM, Vatsyayan R, Martin JR, Russman SM, Yang JC, Baohan A, Richardson RM, Williams ZM, Fried SI, Hoi Sang U, Raslan AM, Ben-Haim S, Halgren E, Cash SS, Dayeh SA Nature communications 38233418 Nat Commun 2024 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/38233418
Syllable processing is organized in discrete subregions of the human superior temporal gyrus. Cleary DR, Tchoe Y, Bourhis A, Dickey CW, Stedelin B, Ganji M, Lee SH, Lee J, Siler DA, Brown EC, Rosen BQ, Kaestner E, Yang JC, Soper DJ, Han SJ, Paulk AC, Cash SS, Raslan AM, Dayeh SA, Halgren E PLoS biology 39241107 PLoS Biol 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/39241107
Constructing 2D maps of human spinal cord activity and isolating the functional midline with high-density microelectrode arrays. Russman SM, Cleary DR, Tchoe Y, Bourhis AM, Stedelin B, Martin J, Brown EC, Zhang X, Kawamoto A, Ryu WHA, Raslan AM, Ciacci JD, Dayeh SA Science translational medicine 36170445 Sci Transl Med 2022 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/36170445
Scalable Thousand Channel Penetrating Microneedle Arrays on Flex for Multimodal and Large Area Coverage BrainMachine Interfaces. Lee SH, Thunemann M, Lee K, Cleary DR, Tonsfeldt KJ, Oh H, Azzazy F, Tchoe Y, Bourhis AM, Hossain L, Ro YG, Tanaka A, Kılıç K, Devor A, Dayeh SA Advanced functional materials 36381629 Adv Funct Mater 2022 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/36381629
A Low-Noise Low-Power 0.001Hz-1kHz Neural Recording System-on-Chip With Sample-Level Duty-Cycling. Wu J, Akinin A, Somayajulu J, Lee MS, Paul A, Lu H, Park Y, Kim SJ, Mercier PP, Cauwenberghs G IEEE transactions on biomedical circuits and systems 38408002 IEEE Trans Biomed Circuits Syst 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38408002
Spatially confined responses of mouse visual cortex to intracortical magnetic stimulation from micro-coils. Ryu SB, Paulk AC, Yang JC, Ganji M, Dayeh SA, Cash SS, Fried SI, Lee SW Journal of neural engineering 32998116 J Neural Eng 2020 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/32998116
A Comprehensive Large Signal, Small Signal, and Noise Model for IGZO Thin Film Transistor Circuits. Vatsyayan R, Dayeh SA IEEE transactions on electron devices 37680851 IEEE Trans Electron Devices 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37680851
Modular Phoneme Processing in Human Superior Temporal Gyrus. Cleary DR, Tchoe Y, Bourhis A, Dickey CW, Stedelin B, Ganji M, Lee SH, Lee J, Siler DA, Brown EC, Rosen BQ, Kaestner E, Yang JC, Soper DJ, Han SJ, Paulk AC, Cash SS, Raslan AMT, Dayeh SA, Halgren E bioRxiv : the preprint server for biology 38293030 bioRxiv 2024 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/38293030
An electroencephalogram microdisplay to visualize neuronal activity on the brain surface. Tchoe Y, Wu T, U HS, Roth DM, Kim D, Lee J, Cleary DR, Pizarro P, Tonsfeldt KJ, Lee K, Chen PC, Bourhis AM, Galton I, Coughlin B, Yang JC, Paulk AC, Halgren E, Cash SS, Dayeh SA Science translational medicine 38657026 Sci Transl Med 2024 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/38657026
Microscale dynamics of electrophysiological markers of epilepsy. Yang JC, Paulk AC, Salami P, Lee SH, Ganji M, Soper DJ, Cleary D, Simon M, Maus D, Lee JW, Nahed BV, Jones PS, Cahill DP, Cosgrove GR, Chu CJ, Williams Z, Halgren E, Dayeh S, Cash SS Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 34419344 Clin Neurophysiol 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34419344
Considerations and recent advances in nanoscale interfaces with neuronal and cardiac networks. Tchoe Y, Lee J, Liu R, Bourhis AM, Vatsyayan R, Tonsfeldt KJ, Dayeh SA Applied physics reviews 34868443 Appl Phys Rev 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34868443
Magnify is a universal molecular anchoring strategy for expansion microscopy. Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y Nature biotechnology 36593399 Nat Biotechnol 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/36593399
Expansion Microscopy: Toward Nanoscale Imaging of a Diverse Range of Biomolecules. Klimas A, Zhao Y ACS nano 32628828 ACS Nano 2020 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/32628828
Super-Resolution Vibrational Imaging Using Expansion Stimulated Raman Scattering Microscopy. Shi L, Klimas A, Gallagher B, Cheng Z, Fu F, Wijesekara P, Miao Y, Ren X, Zhao Y, Min W Advanced science (Weinheim, Baden-Wurttemberg, Germany) 35521971 Adv Sci (Weinh) 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35521971
Basics of Expansion Microscopy. Klimas A, Gallagher B, Zhao Y Current protocols in cytometry 31763769 Curr Protoc Cytom 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31763769
Expansion microscopy: A powerful nanoscale imaging tool for neuroscientists. Gallagher BR, Zhao Y Neurobiology of disease 33813047 Neurobiol Dis 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/33813047
MicroMagnify: A Multiplexed Expansion Microscopy Method for Pathogens and Infected Tissues. Cheng Z, Stefani C, Skillman T, Klimas A, Lee A, DiBernardo EF, Brown KM, Milman T, Wang Y, Gallagher BR, Lagree K, Jena BP, Pulido JS, Filler SG, Mitchell AP, Hiller NL, Lacy-Hulbert A, Zhao Y Advanced science (Weinheim, Baden-Wurttemberg, Germany) 37658522 Adv Sci (Weinh) 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/37658522
Nanoscale imaging of clinical specimens using conventional and rapid-expansion pathology. Bucur O, Fu F, Calderon M, Mylvaganam GH, Ly NL, Day J, Watkin S, Walker BD, Boyden ES, Zhao Y Nature protocols 32238952 Nat Protoc 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32238952
Reciprocal Signaling between Myeloid Derived Suppressor and Tumor Cells Enhances Cellular Motility and is Mediated by Structural Cues in the Microenvironment. Shukla VC, Duarte-Sanmiguel S, Panic A, Senthilvelan A, Moore J, Bobba C, Benner B, Carson WE 3rd, Ghadiali SN, Gallego-Perez D Advanced biosystems 32419350 Adv Biosyst 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32419350
In Situ Deployment of Engineered Extracellular Vesicles into the Tumor Niche via Myeloid-Derived Suppressor Cells. Duarte-Sanmiguel S, Panic A, Dodd DJ, Salazar-Puerta A, Moore JT, Lawrence WR, Nairon K, Francis C, Zachariah N, McCoy W, Turaga R, Skardal A, Carson WE, Higuita-Castro N, Gallego-Perez D Advanced healthcare materials 34662497 Adv Healthc Mater 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/34662497
Designer Extracellular Vesicles Modulate Pro-Neuronal Cell Responses and Improve Intracranial Retention. Ortega-Pineda L, Sunyecz A, Salazar-Puerta AI, Rincon-Benavides MA, Alzate-Correa D, Anaparthi AL, Guilfoyle E, Mezache L, Struckman HL, Duarte-Sanmiguel S, Deng B, McComb DW, Dodd DJ, Lawrence WR, Moore J, Zhang J, Reátegui E, Veeraraghavan R, Nelson MT, Gallego-Perez D, Higuita-Castro N Advanced healthcare materials 35014204 Adv Healthc Mater 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35014204
Nanotransfection-based vasculogenic cell reprogramming drives functional recovery in a mouse model of ischemic stroke. Lemmerman LR, Balch MHH, Moore JT, Alzate-Correa D, Rincon-Benavides MA, Salazar-Puerta A, Gnyawali S, Harris HN, Lawrence W, Ortega-Pineda L, Wilch L, Risser IB, Maxwell AJ, Duarte-Sanmiguel S, Dodd D, Guio-Vega GP, McTigue DM, Arnold WD, Nimjee SM, Sen CK, Khanna S, Rink C, Higuita-Castro N, Gallego-Perez D Science advances 33741587 Sci Adv 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33741587
Engineered Vasculogenic Extracellular Vesicles Drive Nonviral Direct Conversions of Human Dermal Fibroblasts into Induced Endothelial Cells and Improve Wound Closure. Rincon-Benavides MA, Mendonca NC, Cuellar-Gaviria TZ, Salazar-Puerta AI, Ortega-Pineda L, Blackstone BN, Deng B, McComb DW, Gallego-Perez D, Powell HM, Higuita-Castro N Advanced therapeutics 37577183 Adv Ther (Weinh) 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/37577183
Nanomedicine-Based Strategies for Diabetes: Diagnostics, Monitoring, and Treatment. Lemmerman LR, Das D, Higuita-Castro N, Mirmira RG, Gallego-Perez D Trends in endocrinology and metabolism: TEM 32396845 Trends Endocrinol Metab 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32396845
Guided migration analyses at the single-clone level uncover cellular targets of interest in tumor-associated myeloid-derived suppressor cell populations. Duarte-Sanmiguel S, Shukla V, Benner B, Moore J, Lemmerman L, Lawrence W, Panic A, Wang S, Idzkowski N, Guio-Vega G, Higuita-Castro N, Ghadiali S, Carson WE, Gallego-Perez D Scientific reports 31988310 Sci Rep 2020 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/31988310
Transient Middle Cerebral Artery Occlusion with an Intraluminal Suture Enables Reproducible Induction of Ischemic Stroke in Mice. Lemmerman LR, Harris HN, Balch MHH, Rincon-Benavides MA, Higuita-Castro N, Arnold DW, Gallego-Perez D Bio-protocol 35284595 Bio Protoc 2022 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/35284595
Nanotechnology-Driven Cell-Based Therapies in Regenerative Medicine. Alzate-Correa D, Lawrence WR, Salazar-Puerta A, Higuita-Castro N, Gallego-Perez D The AAPS journal 35292878 AAPS J 2022 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/35292878
A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function. Pinckard KM, Shettigar VK, Wright KR, Abay E, Baer LA, Vidal P, Dewal RS, Das D, Duarte-Sanmiguel S, Hernández-Saavedra D, Arts PJ, Lehnig AC, Bussberg V, Narain NR, Kiebish MA, Yi F, Sparks LM, Goodpaster BH, Smith SR, Pratley RE, Lewandowski ED, Raman SV, Wold LE, Gallego-Perez D, Coen PM, Ziolo MT, Stanford KI Circulation 33106031 Circulation 2021 Jan 12 https://www.ncbi.nlm.nih.gov/pubmed/33106031
ICAM-1-decorated extracellular vesicles loaded with miR-146a and Glut1 drive immunomodulation and hinder tumor progression in a murine model of breast cancer. Duarte-Sanmiguel S, Salazar-Puerta AI, Panic A, Dodd D, Francis C, Alzate-Correa D, Ortega-Pineda L, Lemmerman L, Rincon-Benavides MA, Dathathreya K, Lawrence W, Ott N, Zhang J, Deng B, Wang S, Santander SP, McComb DW, Reategui E, Palmer AF, Carson WE, Higuita-Castro N, Gallego-Perez D Biomaterials science 37646133 Biomater Sci 2023 Oct 10 https://www.ncbi.nlm.nih.gov/pubmed/37646133
Injectable pulverized electrospun poly(lactic-co-glycolic acid) fibers improve human adipose tissue engraftment and volume retention. Das D, Lawrence WR, Diaz-Starokozheva L, Salazar-Puerta AI, Ott N, Goebel ER, Damughatla A, Vidal P, Gallentine S, Moore JT, Kayuha D, Mendonca NC, Albert JB, Houser R, Johnson J, Powell H, Higuita-Castro N, Stanford KI, Gallego-Perez D Journal of biomedical materials research. Part A 37326365 J Biomed Mater Res A 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37326365
Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles. Cuellar-Gaviria TZ, Rincon-Benavides MA, Halipci Topsakal HN, Salazar-Puerta AI, Jaramillo-Garrido S, Kordowski M, Vasquez-Martinez CA, Nguyen KT, Rima XY, Rana PSJB, Combita-Heredia O, Deng B, Dathathreya K, McComb DW, Reategui E, Wozniak D, Higuita-Castro N, Gallego-Perez D Journal of controlled release : official journal of the Controlled Release Society 39491627 J Control Release 2024 Dec https://www.ncbi.nlm.nih.gov/pubmed/39491627
Early Intervention in Ischemic Tissue with Oxygen Nanocarriers Enables Successful Implementation of Restorative Cell Therapies. Diaz-Starokozheva L, Das D, Gu X, Moore JT, Lemmerman LR, Valerio I, Powell HM, Higuita-Castro N, Go MR, Palmer AF, Gallego-Perez D Cellular and molecular bioengineering 33184576 Cell Mol Bioeng 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/33184576
Nanochannel-Based Poration Drives Benign and Effective Nonviral Gene Delivery to Peripheral Nerve Tissue. Moore JT, Wier CG, Lemmerman LR, Ortega-Pineda L, Dodd DJ, Lawrence WR, Duarte-Sanmiguel S, Dathathreya K, Diaz-Starokozheva L, Harris HN, Sen CK, Valerio IL, Higuita-Castro N, Arnold WD, Kolb SJ, Gallego-Perez D Advanced biosystems 32939985 Adv Biosyst 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/32939985
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease. Salazar-Puerta AI, Kordowski M, Cuellar-Gaviria TZ, Rincon-Benavides MA, Hussein J, Flemister D, Mayoral-Andrade G, Barringer G, Guilfoyle E, Blackstone BN, Deng B, Zepeda-Orozco D, McComb DW, Powell H, Dasi LP, Gallego-Perez D, Higuita-Castro N Cellular and molecular bioengineering 37810997 Cell Mol Bioeng 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37810997
Engineered Extracellular Vesicles Derived from Dermal Fibroblasts Attenuate Inflammation in a Murine Model of Acute Lung Injury. Salazar-Puerta AI, Rincon-Benavides MA, Cuellar-Gaviria TZ, Aldana J, Vasquez Martinez G, Ortega-Pineda L, Das D, Dodd D, Spencer CA, Deng B, McComb DW, Englert JA, Ghadiali S, Zepeda-Orozco D, Wold LE, Gallego-Perez D, Higuita-Castro N Advanced materials (Deerfield Beach, Fla.) 37119468 Adv Mater 2023 Jul https://www.ncbi.nlm.nih.gov/pubmed/37119468
Engineered extracellular vesicles from human skin cells induce pro-β-cell conversions in pancreatic ductal cells. Ortega-Pineda L, Guilfoyle E, Rincon-Benavides MA, Anaparthi AL, Lemmerman LR, Cuellar-Gaviria TZ, Lawrence W, Buss JL, Deng B, Blackstone BN, Salazar-Puerta A, McComb DW, Powell H, Gallego-Perez D, Higuita-Castro N Advanced nanobiomed research 38911285 Adv Nanobiomed Res 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/38911285
The Fifth Annual Symposium of the Midwest Aging Consortium. Reader BF, Rosas L, Knopf BA, Liu Y, Alzate-Correa D, Bhat A, Carey A, Cuervo AM, Dayal S, Demarco RS, Elliehausen CJ, Englund DA, Hamilton HL, Johnston M, Kang P, Konopka AR, Lepola N, Presley CJ, Schafer MJ, Serrano J, Singer BD, Song MA, Stanford KI, Taylor J, Wei W, Yeh CY, Zhang L, Zhang L, Anderson RM, Bai H, Robbins PD, Lamming DW, Mihaylova MM, Rojas M, Mora AL The journals of gerontology. Series A, Biological sciences and medical sciences 39704343 J Gerontol A Biol Sci Med Sci 2025 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/39704343
3D-printed bioactive scaffolds from nanosilicates and PEOT/PBT for bone tissue engineering. Carrow JK, Di Luca A, Dolatshahi-Pirouz A, Moroni L, Gaharwar AK Regenerative biomaterials 30740240 Regen Biomater 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30740240
Printing Therapeutic Proteins in 3D using Nanoengineered Bioink to Control and Direct Cell Migration. Peak CW, Singh KA, Adlouni M, Chen J, Gaharwar AK Advanced healthcare materials 31066517 Adv Healthc Mater 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31066517
Intra-Articular Injectable Biomaterials for Cartilage Repair and Regeneration. Kalairaj MS, Pradhan R, Saleem W, Smith MM, Gaharwar AK Advanced healthcare materials 38324655 Adv Healthc Mater 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38324655
Dynamically crosslinked thermoresponsive granular hydrogels. Lee HP, Cai KX, Wang TC, Davis R Jr, Deo K, Singh KA, Lele TP, Gaharwar AK Journal of biomedical materials research. Part A 37199446 J Biomed Mater Res A 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/37199446
2D Covalent Organic Framework Direct Osteogenic Differentiation of Stem Cells. Bhunia S, Jaiswal MK, Singh KA, Deo KA, Gaharwar AK Advanced healthcare materials 35104392 Adv Healthc Mater 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35104392
Inorganic Biomaterials Shape the Transcriptome Profile to Induce Endochondral Differentiation. Murali A, Brokesh AM, Cross LM, Kersey AL, Jaiswal MK, Singh I, Gaharwar A Advanced science (Weinheim, Baden-Wurttemberg, Germany) 38738803 Adv Sci (Weinh) 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38738803
Atomic vacancies of molybdenum disulfide nanoparticles stimulate mitochondrial biogenesis. Singh KA, Soukar J, Zulkifli M, Kersey A, Lokhande G, Ghosh S, Murali A, Garza NM, Kaur H, Keeney JN, Banavath R, Ceylan Koydemir H, Sitcheran R, Singh I, Gohil VM, Gaharwar AK Nature communications 39289340 Nat Commun 2024 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/39289340
Nanoengineered Colloidal Inks for 3D Bioprinting. Peak CW, Stein J, Gold KA, Gaharwar AK Langmuir : the ACS journal of surfaces and colloids 28981287 Langmuir 2018 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/28981287
Gradient nanocomposite hydrogels for interface tissue engineering. Cross LM, Shah K, Palani S, Peak CW, Gaharwar AK Nanomedicine : nanotechnology, biology, and medicine 28554596 Nanomedicine 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/28554596
Emerging 2D Nanomaterials for Biomedical Applications. Murali A, Lokhande G, Deo KA, Brokesh A, Gaharwar AK Materials today (Kidlington, England) 34970073 Mater Today (Kidlington) 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34970073
2D Nanoclay for Biomedical Applications: Regenerative Medicine, Therapeutic Delivery, and Additive Manufacturing. Gaharwar AK, Cross LM, Peak CW, Gold K, Carrow JK, Brokesh A, Singh KA Advanced materials (Deerfield Beach, Fla.) 30941811 Adv Mater 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/30941811
Superhydrophobic states of 2D nanomaterials controlled by atomic defects can modulate cell adhesion. Jaiswal MK , Singh KA , Lokhande G , Gaharwar AK Chemical communications (Cambridge, England) 31172998 Chem Commun (Camb) 2019 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/31172998
Dissociation of nanosilicates induces downstream endochondral differentiation gene expression program. Brokesh AM, Cross LM, Kersey AL, Murali A, Richter C, Gregory CA, Singh I, Gaharwar AK Science advances 35476448 Sci Adv 2022 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/35476448
Inorganic ions activate lineage-specific gene regulatory networks. Kersey AL, Singh I, Gaharwar AK Acta biomaterialia 38552761 Acta Biomater 2024 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/38552761
Organelle-Targeting Nanoparticles. Soukar J, Peppas NA, Gaharwar AK Advanced science (Weinheim, Baden-Wurttemberg, Germany) 39806939 Adv Sci (Weinh) 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39806939
Comparison of Photo Cross Linkable Gelatin Derivatives and Initiators for Three-Dimensional Extrusion Bioprinting. Tigner TJ, Rajput S, Gaharwar AK, Alge DL Biomacromolecules 31743018 Biomacromolecules 2020 Feb 10 https://www.ncbi.nlm.nih.gov/pubmed/31743018
Photothermal modulation of human stem cells using light-responsive 2D nanomaterials. Carrow JK, Singh KA, Jaiswal MK, Ramirez A, Lokhande G, Yeh AT, Sarkar TR, Singh I, Gaharwar AK Proceedings of the National Academy of Sciences of the United States of America 32461372 Proc Natl Acad Sci U S A 2020 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/32461372
Nanoclay Reinforced Biomaterials for Mending Musculoskeletal Tissue Disorders. Erezuma I, Eufrasio-da-Silva T, Golafshan N, Deo K, Mishra YK, Castilho M, Gaharwar AK, Leeuwenburgh S, Dolatshahi-Pirouz A, Orive G Advanced healthcare materials 34185438 Adv Healthc Mater 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34185438
Nano-bio interactions of 2D molybdenum disulfide. Roy S, Deo KA, Singh KA, Lee HP, Jaiswal A, Gaharwar AK Advanced drug delivery reviews 35636569 Adv Drug Deliv Rev 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/35636569
2D layered nanomaterials for therapeutics delivery. Davis R Jr, Urbanowski RA Jr, Gaharwar AK Current opinion in biomedical engineering 35814330 Curr Opin Biomed Eng 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/35814330
Clickable PEG hydrogel microspheres as building blocks for 3D bioprinting. Xin S , Chimene D , Garza JE , Gaharwar AK , Alge DL Biomaterials science 30656307 Biomater Sci 2019 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/30656307
Self-assembled, ellipsoidal polymeric nanoparticles for intracellular delivery of therapeutics. Desai P, Venkataramanan A, Schneider R, Jaiswal MK, Carrow JK, Purwada A, Singh A, Gaharwar AK Journal of biomedical materials research. Part A 29577576 J Biomed Mater Res A 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29577576
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs. Kersey AL, Cheng DY, Deo KA, Dubell CR, Wang TC, Jaiswal MK, Kim MH, Murali A, Hargett SE, Mallick S, Lele TP, Singh I, Gaharwar AK Biomaterials 38335719 Biomaterials 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38335719
Sustained and Prolonged Delivery of Protein Therapeutics from Two-Dimensional Nanosilicates. Cross LM, Carrow JK, Ding X, Singh KA, Gaharwar AK ACS applied materials & interfaces 30676016 ACS Appl Mater Interfaces 2019 Feb 20 https://www.ncbi.nlm.nih.gov/pubmed/30676016
Dynamically Cross-Linked Granular Hydrogels for 3D Printing and Therapeutic Delivery. Lee HP, Davis R Jr, Wang TC, Deo KA, Cai KX, Alge DL, Lele TP, Gaharwar AK ACS applied bio materials 37584641 ACS Appl Bio Mater 2023 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/37584641
Granular Biphasic Colloidal Hydrogels for 3D Bioprinting. Deo KA, Murali A, Tronolone JJ, Mandrona C, Lee HP, Rajput S, Hargett SE, Selahi A, Sun Y, Alge DL, Jain A, Gaharwar AK Advanced healthcare materials 38749006 Adv Healthc Mater 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/38749006
Organ-on-chips made of blood: endothelial progenitor cells from blood reconstitute vascular thromboinflammation in vessel-chips. Mathur T, Singh KA, R Pandian NK, Tsai SH, Hein TW, Gaharwar AK, Flanagan JM, Jain A Lab on a chip 31246211 Lab Chip 2019 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/31246211
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Four Key Steps Control Glycolytic Flux in Mammalian Cells. Tanner LB, Goglia AG, Wei MH, Sehgal T, Parsons LR, Park JO, White E, Toettcher JE, Rabinowitz JD Cell systems 29960885 Cell Syst 2018 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/29960885
Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix. Iuliano JN, Collado JT, Gil AA, Ravindran PT, Lukacs A, Shin S, Woroniecka HA, Adamczyk K, Aramini JM, Edupuganti UR, Hall CR, Greetham GM, Sazanovich IV, Clark IP, Daryaee T, Toettcher JE, French JB, Gardner KH, Simmerling CL, Meech SR, Tonge PJ ACS chemical biology 32880430 ACS Chem Biol 2020 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/32880430
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Revealing new biology from multiplexed, metal-isotope-tagged, single-cell readouts. Baskar R, Kimmey SC, Bendall SC Trends in cell biology 35181197 Trends Cell Biol 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35181197
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A Universal Live Cell Barcoding-Platform for Multiplexed Human Single Cell Analysis. Hartmann FJ, Simonds EF, Bendall SC Scientific reports 30018331 Sci Rep 2018 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/30018331
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Immune monitoring using mass cytometry and related high-dimensional imaging approaches. Hartmann FJ, Bendall SC Nature reviews. Rheumatology 31892734 Nat Rev Rheumatol 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31892734
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Mass-tag barcoding for multiplexed analysis of human synaptosomes and other anuclear events. Gajera CR, Fernandez R, Montine KS, Fox EJ, Mrdjen D, Postupna NO, Keene CD, Bendall SC, Montine TJ Cytometry. Part A : the journal of the International Society for Analytical Cytology 33818911 Cytometry A 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/33818911
A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging. Keren L, Bosse M, Marquez D, Angoshtari R, Jain S, Varma S, Yang SR, Kurian A, Van Valen D, West R, Bendall SC, Angelo M Cell 30193111 Cell 2018 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/30193111
High-Parameter Immune Profiling with CyTOF. Sahaf B, Rahman A, Maecker HT, Bendall SC Methods in molecular biology (Clifton, N.J.) 31502160 Methods Mol Biol 2020 https://www.ncbi.nlm.nih.gov/pubmed/31502160
Single-cell metabolic profiling of human cytotoxic T cells. Hartmann FJ, Mrdjen D, McCaffrey E, Glass DR, Greenwald NF, Bharadwaj A, Khair Z, Verberk SGS, Baranski A, Baskar R, Graf W, Van Valen D, Van den Bossche J, Angelo M, Bendall SC Nature biotechnology 32868913 Nat Biotechnol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/32868913
An Integrated Multi-omic Single-Cell Atlas of Human B Cell Identity. Glass DR, Tsai AG, Oliveria JP, Hartmann FJ, Kimmey SC, Calderon AA, Borges L, Glass MC, Wagar LE, Davis MM, Bendall SC Immunity 32668225 Immunity 2020 Jul 14 https://www.ncbi.nlm.nih.gov/pubmed/32668225
Mass Synaptometry: Applying Mass Cytometry to Single Synapse Analysis. Gajera CR, Fernandez R, Postupna N, Montine KS, Keene CD, Bendall SC, Montine TJ Methods in molecular biology (Clifton, N.J.) 35099792 Methods Mol Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/35099792
Modular Antigen-Specific T-cell Biofactories for Calibrated In Vivo Synthesis of Engineered Proteins. Repellin CE, Patel P, Beviglia L, Javitz H, Sambucetti L, Bhatnagar P Advanced biosystems 30984819 Adv Biosyst 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30984819
Lentivirus Manufacturing Process for Primary T-Cell Biofactory Production. Radhakrishnan H, Javitz HS, Bhatnagar P Advanced biosystems 32390316 Adv Biosyst 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32390316
NK-Cell Biofactory as an Off-the-Shelf Cell-based Vector for Targeted In Situ Synthesis of Engineered Proteins. Repellin CE, Ssemadaali MA, Newmyer S, Radhakrishnan H, Javitz HS, Bhatnagar P Advanced biology 33871182 Adv Biol (Weinh) 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/33871182
Cell-Based Platform for Antigen Testing and Its Application for SARS-CoV-2 Infection. Ssemadaali MA, Newmyer S, Radhakrishnan H, Arredondo J, Javitz HS, Dandekar S, Bhatnagar P Microbiology spectrum 35852348 Microbiol Spectr 2022 Aug 31 https://www.ncbi.nlm.nih.gov/pubmed/35852348
Electrically regulated cell-based intervention for viral infections. Newmyer S, Ssemadaali MA, Radhakrishnan H, Javitz HS, Bhatnagar P Bioengineering & translational medicine 36925710 Bioeng Transl Med 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/36925710
Primary T-cell-based delivery platform for in vivo synthesis of engineered proteins. Radhakrishnan H, Newmyer SL, Ssemadaali MA, Javitz HS, Bhatnagar P Bioengineering & translational medicine 38193126 Bioeng Transl Med 2024 Jan https://www.ncbi.nlm.nih.gov/pubmed/38193126
Genetically engineered pair of cells for serological testing and its application for SARS-CoV-2. Ssemadaali MA, Arredondo J, Buser EA, Newmyer S, Radhakrishnan H, Javitz HS, Dandekar S, Bhatnagar P Bioengineering & translational medicine 37206248 Bioeng Transl Med 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37206248
Engineered CD4 T cells for in vivo delivery of therapeutic proteins. Radhakrishnan H, Newmyer SL, Javitz HS, Bhatnagar P Proceedings of the National Academy of Sciences of the United States of America 39312667 Proc Natl Acad Sci U S A 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/39312667
Engineered Ovarian Cancer Cell Lines for Validation of CAR T Cell Function. Repellin CE, Ganesan P, Alcudia JF, Lakshmireddy HKD, Patel P, Beviglia L, Javitz HS, Sambucetti L, Bhatnagar P Advanced biosystems 32293122 Adv Biosyst 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/32293122
Using Communication Theory of Identity to Evaluate Decision Aids: Focus Group Research with African American Prostate Cancer Survivors. Upshaw SJ Health communication 31814430 Health Commun 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/31814430
Higher Ultraviolet Radiation Exposure Among Rural-Dwelling Versus Urban-Dwelling Adults and Children: Implications for Skin Cancer Prevention. Nagelhout ES, Lensink R, Zhu A, Parsons BG, Haaland B, Hashibe M, Grossman D, VanDerslice J, Gren LH, Jensen JD, Wu YP Journal of community health 32542551 J Community Health 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/32542551
Temporal frames, temporal focus, and behavioral expectations: The persuasive impact of near and distant threats. Pokharel M, Jensen JD, Taylor-Burton S, King AJ, John KK, Upshaw S Social science & medicine (1982) 37229932 Soc Sci Med 2023 Jul https://www.ncbi.nlm.nih.gov/pubmed/37229932
Revisiting nutrition backlash: Psychometric properties and discriminant validity of the nutrition backlash scale. Jensen JD, Giorgi EA, Jackson JR, Berger J, Katz RA, Mobley AR Nutrition (Burbank, Los Angeles County, Calif.) 32871324 Nutrition 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32871324
Validating Cross-Modal Measures for Comparative Research: Message Veracity, Novelty, and Memorability. Jensen JD, Krakow MM, Christy KR, Ratcliff CL, Pokharel M, Lillie H Psychology & marketing 38962756 Psychol Mark 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/38962756
Do 360-Character Wireless Emergency Alert (WEA) Messages Work Better than 90-Character Messages? Testing the Risk Communication Consensus. Carlson EJ, Bean H, Ratcliff C, Pokharel M, Barbour J Journal of contingencies and crisis management 39328310 J Conting Crisis Manag 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/39328310
Emerging applications of eye-tracking technology in dermatology. John KK, Jensen JD, King AJ, Pokharel M, Grossman D Journal of dermatological science 29655589 J Dermatol Sci 2018 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/29655589
Do Pattern-Focused Visuals Improve Skin Self-Examination Performance? Explicating the Visual Skill Acquisition Model. John KK, Jensen JD, King AJ, Ratcliff CL, Grossman D Journal of health communication 28759333 J Health Commun 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/28759333
Death Narratives, Negative Emotion, and Counterarguing: Testing Fear, Anger, and Sadness as Mechanisms of Effect. Lillie HM, Jensen JD, Pokharel M, Upshaw SJ Journal of health communication 34569434 J Health Commun 2021 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/34569434
Are some narratives better than others?: The impact of different narrative forms on adolescents' intentions to text and drive. Scherr CL, Lillie H, Ratcliff CL, Krakow M, Liu M, Jensen JD Risk analysis : an official publication of the Society for Risk Analysis 35104924 Risk Anal 2022 Oct https://www.ncbi.nlm.nih.gov/pubmed/35104924
Cancer Information Overload Across Time: Evidence from Two Longitudinal Studies. Lillie H, Katz RA, Carcioppolo N, Giorgi EA, Jensen JD Health communication 35172651 Health Commun 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/35172651
Tailored visuals, implementation interventions, and sun safe behavior: A longitudinal message experiment. Jensen JD, Parsons BG, Nagelhout ES, Pokharel M, Christy KR, Ratcliff CL, Grossman D, Haaland B, Wu YP Health psychology : official journal of the Division of Health Psychology, American Psychological Association 36074598 Health Psychol 2023 Jan https://www.ncbi.nlm.nih.gov/pubmed/36074598
Increasing Skin Cancer Prevention in Young Adults: the Cumulative Impact of Personalized UV Photography and MC1R Genetic Testing. Wu YP, Hamilton JG, Kaphingst KA, Jensen JD, Kohlmann W, Parsons BG, Lillie HM, Wang X, Haaland B, Wankier AP, Grossman D, Hay JL Journal of cancer education : the official journal of the American Association for Cancer Education 36306029 J Cancer Educ 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/36306029
Healthcare Providers' Resilience Communication: A New Type of Patient-Centered Communication. Lillie HM Journal of health communication 38982683 J Health Commun 2024 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/38982683
'I had a bigger cancer risk than I thought…': The experience of receiving personalized risk information as part of a skin cancer prevention intervention in the college setting. Brady HL, Hamilton JG, Kaphingst KA, Jensen JD, Kohlmann W, Parsons BG, Lillie HM, Wankier AP, Smith HJ, Grossman D, Hay JL, Wu YP Health expectations : an international journal of public participation in health care and health policy 36225123 Health Expect 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36225123
Developing skin cancer education materials for darker skin populations: crowdsourced design, message targeting, and acral lentiginous melanoma. Upshaw SJ, Jensen JD, Giorgi EA, Pokharel M, Lillie HM, Adams DR, John KK, Wu YP, Grossman D Journal of behavioral medicine 36125669 J Behav Med 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/36125669
Visual Tailoring and Skin Cancer Prevention: Comparing Personalized, Stock, and Non-Ultraviolet Images. Pokharel M, Jensen JD, John KK, Christy KR, Taylor-Burton S, Upshaw S Health communication 35765121 Health Commun 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/35765121
The Impact of Social and Material Resources on Resilience Communication at the Intersection of Race and Gender. Lillie HM, Sánchez Sánchez V Journal of health communication 36484127 J Health Commun 2022 Oct 3 https://www.ncbi.nlm.nih.gov/pubmed/36484127
The Feasibility and Acceptability of Using a Wearable UV Radiation Exposure Monitoring Device in Adults and Children: Cross-Sectional Questionnaire Study. Nagelhout ES, Lensink R, Zhu A, Parsons BG, Jensen JD, Wu YP JMIR dermatology 33043275 JMIR Dermatol 2020 https://www.ncbi.nlm.nih.gov/pubmed/33043275
Theorizing Foreshadowed Death Narratives: Examining the Impact of Character Death on Narrative Processing and Skin Self-Exam Intentions. Jensen JD, Yale RN, Krakow M, John KK, King AJ Journal of health communication 28060585 J Health Commun 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/28060585
Does it matter if a story character lives or dies?: a message experiment comparing survivor and death narratives. Lillie HM, Pokharel M, John KK, Christy KR, Upshaw S, Giorgi EA, Jensen JD Psychology & health 33464969 Psychol Health 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/33464969
Differences in reported sun protection practices, skin cancer knowledge, and perceived risk for skin cancer between rural and urban high school students. Nagelhout ES, Parsons BG, Haaland B, Tercyak KP, Zaugg K, Zhu A, Harding G, Yancey J, Jensen JD, Grossman D, Wetter DW, Wu YP Cancer causes & control : CCC 31522321 Cancer Causes Control 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31522321
Cancer information overload: Discriminant validity and relationship to sun safe behaviors. Jensen JD, Pokharel M, Carcioppolo N, Upshaw S, John KK, Katz RA Patient education and counseling 31522897 Patient Educ Couns 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31522897
Political Party Collective Norms, Perceived Norms, and Mask Wearing Behavior: A Test of the Theory of Normative Social Behavior. Pokharel M, Lillie HM, Jensen JD, King AJ, Ratcliff CL, Barbour JB Health communication 38281912 Health Commun 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/38281912
People Wear Masks when they Ski: Comparing Congruent and Incongruent Behavioral Context Appeals. Liao Y, Adams DR, Lillie HM, Jensen JD Journal of health communication 37768095 J Health Commun 2023 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/37768095
Do ultraviolet photos increase sun safe behavior expectations via fear? A randomized controlled trial in a sample of U.S. adults. Pokharel M, Christy KR, Jensen JD, Giorgi EA, John KK, Wu YP Journal of behavioral medicine 30523504 J Behav Med 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/30523504
A four-group experiment to improve Western high school students' sun protection behaviors. Wu YP, Parsons BG, Nagelhout E, Haaland B, Jensen J, Zaugg K, Caputo H, Lensink R, Harding G, Yancey J, Klein SZ, Leachman SA, Tercyak KP Translational behavioral medicine 31094440 Transl Behav Med 2019 May 16 https://www.ncbi.nlm.nih.gov/pubmed/31094440
Obstacles to skin self-examination: are frontier adults inclined abstainers? Jensen JD, Pokharel M, King AJ, John KK, Wu YP, Grossman D Psychology, health & medicine 31847571 Psychol Health Med 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/31847571
Is News Surveillance related to Cancer Knowledge in Underserved Adults? Testing Three Versions of the Cognitive Mediation Model. Jensen JD, King AJ, Torres DP, Krakow M, Coe K, Upshaw S Journalism studies 33100901 Journal Stud 2020 https://www.ncbi.nlm.nih.gov/pubmed/33100901
Spit, Disgust, and Parasite Stress Theory: A Message Experiment. Chavez-Yenter D, Lille HM, Gorissen S, John KK, Vega AS, Jensen JD Journal of health communication 37382498 J Health Commun 2023 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/37382498
Using narratives to correct politically charged health misinformation and address affective belief echoes. Lillie HM, Ratcliff CL, King AJ, Pokharel M, Jensen JD Journal of public health (Oxford, England) 38632889 J Public Health (Oxf) 2024 Aug 25 https://www.ncbi.nlm.nih.gov/pubmed/38632889
Resilience Communication Mitigates the Negative Relational Effects of Topic Avoidance: Evidence from Parental Caregiving and COVID-19 Pandemic Contexts. Lillie HM, Venetis MK, Chernichky-Karcher S Personal Relationships 38737382 Pers Relatsh 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/38737382
Reactivity to UV Radiation Exposure Monitoring Using Personal Exposure Devices for Skin Cancer Prevention: Longitudinal Observational Study. Parsons BG, Nagelhout ES, Wankier AP, Hu N, Lensink R, Zhu A, Nottingham K, Grossman D, Jensen JD, Wu YP JMIR mHealth and uHealth 34581683 JMIR Mhealth Uhealth 2021 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/34581683
Communicating scientific uncertainty in the early stages of the COVID-19 pandemic: A message experiment. Adams DR, Ratcliff CL, Pokharel M, Jensen JD, Liao Y Risk analysis : an official publication of the Society for Risk Analysis 37963681 Risk Anal 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/37963681
A Missing Mechanism of Effect: How People Who Habitually Replot Stories React Differently (Or Not so Differently) to Melanoma Narratives. Lillie HM, Pokharel M, Jensen JD Journal of health communication 39550610 J Health Commun 2025 Mar 28 https://www.ncbi.nlm.nih.gov/pubmed/39550610
Compact and adjustable compensator for AOD spatial and temporal dispersion using off-the-shelf components. Yamaguchi A, Karagyozov D, Gershow MH Optics letters 33793507 Opt Lett 2021 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/33793507
Direction Selectivity in Drosophila Proprioceptors Requires the Mechanosensory Channel Tmc. He L, Gulyanon S, Mihovilovic Skanata M, Karagyozov D, Heckscher ES, Krieg M, Tsechpenakis G, Gershow M, Tracey WD Jr Current biology : CB 30853433 Curr Biol 2019 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/30853433
Switch-like and persistent memory formation in individual Drosophila larvae. Lesar A, Tahir J, Wolk J, Gershow M eLife 34636720 Elife 2021 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/34636720
Recording Neural Activity in Unrestrained Animals with Three-Dimensional Tracking Two-Photon Microscopy. Karagyozov D, Mihovilovic Skanata M, Lesar A, Gershow M Cell reports 30380425 Cell Rep 2018 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/30380425
Neural Substrates of Drosophila Larval Anemotaxis. Jovanic T, Winding M, Cardona A, Truman JW, Gershow M, Zlatic M Current biology : CB 30744969 Curr Biol 2019 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/30744969
Variance adaptation in navigational decision making. Gepner R, Wolk J, Wadekar DS, Dvali S, Gershow M eLife 30480547 Elife 2018 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/30480547
Dedicated photoreceptor pathways in Drosophila larvae mediate navigation by processing either spatial or temporal cues. Humberg TH, Bruegger P, Afonso B, Zlatic M, Truman JW, Gershow M, Samuel A, Sprecher SG Nature communications 29593252 Nat Commun 2018 Mar 28 https://www.ncbi.nlm.nih.gov/pubmed/29593252
Multi-neuronal recording in unrestrained animals with all acousto-optic random-access line-scanning two-photon microscopy. Yamaguchi A, Wu R, McNulty P, Karagyozov D, Mihovilovic Skanata M, Gershow M Frontiers in neuroscience 37389365 Front Neurosci 2023 https://www.ncbi.nlm.nih.gov/pubmed/37389365
CRASH2p: Closed-loop Two Photon Imaging in a Freely Moving Animal. McNulty P, Wu R, Yamaguchi A, Heckscher ES, Haas A, Nwankpa A, Skanata MM, Gershow M bioRxiv : the preprint server for biology 38826435 bioRxiv 2024 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/38826435
Role of indentation depth and contact area on human perception of softness for haptic interfaces. Dhong C, Miller R, Root NB, Gupta S, Kayser LV, Carpenter CW, Loh KJ, Ramachandran VS, Lipomi DJ Science advances 31497646 Sci Adv 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31497646
Effects of flexibility and branching of side chains on the mechanical properties of low-bandgap conjugated polymers. Sugiyama F, Kleinschmidt AT, Kayser LV, Rodriquez D, Finn M 3rd, Alkhadra MA, Wan JM, Ramírez J, Chiang AS, Root SE, Savagatrup S, Lipomi DJ Polymer chemistry 30873221 Polym Chem 2018 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/30873221
Metallic Nanoislands on Graphene for Biomechanical Sensing. Ramírez J, Polat B, Lipomi DJ ACS omega 32656394 ACS Omega 2020 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/32656394
Role of fingerprint-inspired relief structures in elastomeric slabs for detecting frictional differences arising from surface monolayers. Dhong C , Kayser LV , Arroyo R , Shin A , Finn M , Kleinschmidt AT , Lipomi DJ Soft matter 30152497 Soft Matter 2018 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/30152497
Electropneumotactile Stimulation: Multimodal Haptic Actuators Enabled by a Stretchable Conductive Polymer on Inflatable Pockets. Carpenter CW, Malinao MG, Rafeedi TA, Rodriquez D, Melissa Tan ST, Root NB, Skelil K, Ramírez J, Polat B, Root SE, Ramachandran VS, Lipomi DJ Advanced materials technologies 32905479 Adv Mater Technol 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32905479
Single-Nanowire Strain Sensors Fabricated by Nanoskiving. Jibril L, Ramírez J, Zaretski AV, Lipomi DJ Sensors and actuators. A, Physical 28860679 Sens Actuators A Phys 2017 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/28860679
RAFT Polymerization of an Intrinsically Stretchable Water-Soluble Block Copolymer Scaffold for PEDOT. Kayser LV, Russell MD, Rodriquez D, Abuhamdieh SN, Dhong C, Khan S, Stein AN, Ramírez J, Lipomi DJ Chemistry of materials : a publication of the American Chemical Society 30930534 Chem Mater 2018 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/30930534
Stretchable Conductive Polymers and Composites Based on PEDOT and PEDOT:PSS. Kayser LV, Lipomi DJ Advanced materials (Deerfield Beach, Fla.) 30600559 Adv Mater 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30600559
Metallic nanoislands on graphene: A metamaterial for chemical, mechanical, optical, and biological applications. Marin BC, Ramirez J, Root SE, Aklile E, Lipomi DJ Nanoscale horizons 29276626 Nanoscale Horiz 2017 https://www.ncbi.nlm.nih.gov/pubmed/29276626
Metallic Nanoislands on Graphene for Monitoring Swallowing Activity in Head and Neck Cancer Patients. Ramírez J, Rodriquez D, Qiao F, Warchall J, Rye J, Aklile E, S-C Chiang A, Marin BC, Mercier PP, Cheng CK, Hutcheson KA, Shinn EH, Lipomi DJ ACS nano 29874030 ACS Nano 2018 Jun 26 https://www.ncbi.nlm.nih.gov/pubmed/29874030
Exploring the limits of sensitivity for strain gauges of graphene and hexagonal boron nitride decorated with metallic nanoislands. Ramírez J, Urbina AD, Kleinschmidt AT, Finn M 3rd, Edmunds SJ, Esparza GL, Lipomi DJ Nanoscale 32409812 Nanoscale 2020 May 28 https://www.ncbi.nlm.nih.gov/pubmed/32409812
Graphene-Metal Composite Sensors with Near-Zero Temperature Coefficient of Resistance. Marin BC, Root SE, Urbina AD, Aklile E, Miller R, Zaretski AV, Lipomi DJ ACS omega 28261691 ACS Omega 2017 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/28261691
Combining High Sensitivity and Dynamic Range: Wearable Thin-Film Composite Strain Sensors of Graphene, Ultrathin Palladium, and PEDOT:PSS. Ramírez J, Rodriquez D, Urbina A, Cardenas A, Lipomi DJ ACS applied nano materials 33829151 ACS Appl Nano Mater 2019 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/33829151
The Language of Glove: Wireless gesture decoder with low-power and stretchable hybrid electronics. O'Connor TF, Fach ME, Miller R, Root SE, Mercier PP, Lipomi DJ PloS one 28700603 PLoS One 2017 https://www.ncbi.nlm.nih.gov/pubmed/28700603
Stretchable and Degradable Semiconducting Block Copolymers. Sugiyama F, Kleinschmidt AT, Kayser LV, Alkhadra MA, Wan JM, Chiang AS, Rodriquez D, Root SE, Savagatrup S, Lipomi DJ Macromolecules 30930487 Macromolecules 2018 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/30930487
SERS-enhanced piezoplasmonic graphene composite for biological and structural strain mapping. Marin BC, Liu J, Aklile E, Urbina AD, Chiang AS, Lawrence N, Chen S, Lipomi DJ Nanoscale 28055038 Nanoscale 2017 Jan 19 https://www.ncbi.nlm.nih.gov/pubmed/28055038
Ionotactile Stimulation: Nonvolatile Ionic Gels for Human-Machine Interfaces. Root SE, Carpenter CW, Kayser LV, Rodriquez D, Davies DM, Wang S, Tan STM, Meng YS, Lipomi DJ ACS omega 29399651 ACS Omega 2018 Jan 31 https://www.ncbi.nlm.nih.gov/pubmed/29399651
Healable Thermoplastic for Kinesthetic Feedback in Wearable Haptic Devices. Carpenter CW, Ting Melissa Tan S, Keef C, Skelil K, Malinao M, Rodriquez D, Alkhadra MA, Ramírez J, Lipomi DJ Sensors and actuators. A, Physical 31777429 Sens Actuators A Phys 2019 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/31777429
Stretchable Conjugated Polymers: A Case Study in Topic Selection for New Research Groups. Kleinschmidt AT, Lipomi DJ Accounts of chemical research 30516970 Acc Chem Res 2018 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/30516970
Virtual Texture Generated using Elastomeric Conductive Block Copolymer in Wireless Multimodal Haptic Glove. Keef CV, Kayser LV, Tronboll S, Carpenter CW, Root NB, Finn M 3rd, O'Connor TF, Abuhamdieh SN, Davies DM, Runser R, Meng YS, Ramachandran VS, Lipomi DJ Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) 32656536 Adv Intell Syst 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32656536
Organic Haptics: Intersection of Materials Chemistry and Tactile Perception. Lipomi DJ, Dhong C, Carpenter CW, Root NB, Ramachandran VS Advanced functional materials 34276273 Adv Funct Mater 2020 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/34276273
Polymer Chemistry for Haptics, Soft Robotics, and Human-Machine Interfaces. Schara S, Blau R, Church DC, Pokorski JK, Lipomi DJ Advanced functional materials 34924911 Adv Funct Mater 2021 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/34924911
Therapeutic hypothermia reduces cortical inflammation associated with utah array implants. Dugan EA, Bennett C, Tamames I, Dietrich WD, King CS, Prasad A, Rajguru SM Journal of neural engineering 32240985 J Neural Eng 2020 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/32240985
Common marmoset (Callithrix jacchus) as a primate model for behavioral neuroscience studies. Prins NW, Pohlmeyer EA, Debnath S, Mylavarapu R, Geng S, Sanchez JC, Rothen D, Prasad A Journal of neuroscience methods 28400103 J Neurosci Methods 2017 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/28400103
Spinal cord neural interfacing in common marmosets (Callithrix jacchus). Prins NW, Mylavarapu R, Shoup AM, Debnath S, Prasad A Journal of neural engineering 31480029 J Neural Eng 2020 Jan 14 https://www.ncbi.nlm.nih.gov/pubmed/31480029
Chronic recordings from the marmoset motor cortex reveals modulation of neural firing and local field potentials overlap with macaques. Mylavarapu R, Prins NW, Pohlmeyer EA, Shoup AM, Debnath S, Geng S, Sanchez JC, Schwartz O, Prasad A Journal of neural engineering 34225263 J Neural Eng 2021 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/34225263
The complement cascade at the Utah microelectrode-tissue interface. Bennett C, Álvarez-Ciara A, Franklin M, Dietrich WD, Prasad A Biomaterials 33310540 Biomaterials 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33310540
Long-term stability of neural signals from microwire arrays implanted in common marmoset motor cortex and striatum. Debnath S, Prins NW, Pohlmeyer E, Mylavarapu R, Geng S, Sanchez JC, Prasad A Biomedical physics & engineering express 31011432 Biomed Phys Eng Express 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/31011432
Neuroinflammation, oxidative stress, and blood-brain barrier (BBB) disruption in acute Utah electrode array implants and the effect of deferoxamine as an iron chelator on acute foreign body response. Bennett C, Mohammed F, Álvarez-Ciara A, Nguyen MA, Dietrich WD, Rajguru SM, Streit WJ, Prasad A Biomaterials 30343257 Biomaterials 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30343257
Blood brain barrier (BBB)-disruption in intracortical silicon microelectrode implants. Bennett C, Samikkannu M, Mohammed F, Dietrich WD, Rajguru SM, Prasad A Biomaterials 29477707 Biomaterials 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29477707
Biologically Inspired Smart Release System Based on 3D Bioprinted Perfused Scaffold for Vascularized Tissue Regeneration. Cui H, Zhu W, Holmes B, Zhang LG Advanced science (Weinheim, Baden-Wurttemberg, Germany) 27818910 Adv Sci (Weinh) 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27818910
Engineering a Novel 3D Printed Vascularized Tissue Model for Investigating Breast Cancer Metastasis to Bone. Cui H, Esworthy T, Zhou X, Hann SY, Glazer RI, Li R, Zhang LG Advanced healthcare materials 31846231 Adv Healthc Mater 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/31846231
Recent advances in 3D printing: vascular network for tissue and organ regeneration. Hann SY, Cui H, Esworthy T, Miao S, Zhou X, Lee SJ, Fisher JP, Zhang LG Translational research : the journal of laboratory and clinical medicine 31004563 Transl Res 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31004563
4D printing smart biomedical scaffolds with novel soybean oil epoxidized acrylate. Miao S, Zhu W, Castro NJ, Nowicki M, Zhou X, Cui H, Fisher JP, Zhang LG Scientific reports 27251982 Sci Rep 2016 Jun 2 https://www.ncbi.nlm.nih.gov/pubmed/27251982
Hierarchical Fabrication of Engineered Vascularized Bone Biphasic Constructs via Dual 3D Bioprinting: Integrating Regional Bioactive Factors into Architectural Design. Cui H, Zhu W, Nowicki M, Zhou X, Khademhosseini A, Zhang LG Advanced healthcare materials 27383032 Adv Healthc Mater 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/27383032
A 3D printed nano bone matrix for characterization of breast cancer cell and osteoblast interactions. Zhu W, Castro NJ, Cui H, Zhou X, Boualam B, McGrane R, Glazer RI, Zhang LG Nanotechnology 27346678 Nanotechnology 2016 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/27346678
Four-Dimensional Printing Hierarchy Scaffolds with Highly Biocompatible Smart Polymers for Tissue Engineering Applications. Miao S, Zhu W, Castro NJ, Leng J, Zhang LG Tissue engineering. Part C, Methods 28195832 Tissue Eng Part C Methods 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/28195832
4D printing of polymeric materials for tissue and organ regeneration. Miao S, Castro N, Nowicki M, Xia L, Cui H, Zhou X, Zhu W, Lee SJ, Sarkar K, Vozzi G, Tabata Y, Fisher J, Zhang LG Materials today (Kidlington, England) 29403328 Mater Today (Kidlington) 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/29403328
Cold Atmospheric Plasma Modified Electrospun Scaffolds with Embedded Microspheres for Improved Cartilage Regeneration. Zhu W, Castro NJ, Cheng X, Keidar M, Zhang LG PloS one 26222527 PLoS One 2015 https://www.ncbi.nlm.nih.gov/pubmed/26222527
Design of a Novel 3D Printed Bioactive Nanocomposite Scaffold for Improved Osteochondral Regeneration. Castro NJ, Patel R, Zhang LG Cellular and molecular bioengineering 26366231 Cell Mol Bioeng 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26366231
In vitro and in vivo evaluation of 3D bioprinted small-diameter vasculature with smooth muscle and endothelium. Cui H, Zhu W, Huang Y, Liu C, Yu ZX, Nowicki M, Miao S, Cheng Y, Zhou X, Lee SJ, Zhou Y, Wang S, Mohiuddin M, Horvath K, Zhang LG Biofabrication 31470437 Biofabrication 2019 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/31470437
4D physiologically adaptable cardiac patch: A 4-month in vivo study for the treatment of myocardial infarction. Cui H, Liu C, Esworthy T, Huang Y, Yu ZX, Zhou X, San H, Lee SJ, Hann SY, Boehm M, Mohiuddin M, Fisher JP, Zhang LG Science advances 32637623 Sci Adv 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32637623
A novel near-infrared light responsive 4D printed nanoarchitecture with dynamically and remotely controllable transformation. Cui H, Miao S, Esworthy T, Lee SJ, Zhou X, Hann SY, Webster TJ, Harris BT, Zhang LG Nano research 33312444 Nano Res 2019 https://www.ncbi.nlm.nih.gov/pubmed/33312444
Integrating biologically inspired nanomaterials and table-top stereolithography for 3D printed biomimetic osteochondral scaffolds. Castro NJ, O'Brien J, Zhang LG Nanoscale 26234364 Nanoscale 2015 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/26234364
Stereolithographic 4D Bioprinting of Multiresponsive Architectures for Neural Engineering. Miao S, Cui H, Nowicki M, Xia L, Zhou X, Lee SJ, Zhu W, Sarkar K, Zhang Z, Zhang LG Advanced biosystems 30906853 Adv Biosyst 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30906853
A synergistic approach to the design, fabrication and evaluation of 3D printed micro and nano featured scaffolds for vascularized bone tissue repair. Holmes B, Bulusu K, Plesniak M, Zhang LG Nanotechnology 26758780 Nanotechnology 2016 Feb 12 https://www.ncbi.nlm.nih.gov/pubmed/26758780
How can 3D printing be a powerful tool in nanomedicine? Zhu W, Webster TJ, Zhang LG Nanomedicine (London, England) 29338559 Nanomedicine (Lond) 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29338559
Integration of biological systems with electronic-mechanical assemblies. Yi N, Cui H, Zhang LG, Cheng H Acta biomaterialia 31004844 Acta Biomater 2019 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/31004844
Enhanced bone tissue regeneration using a 3D printed microstructure incorporated with a hybrid nano hydrogel. Heo DN, Castro NJ, Lee SJ, Noh H, Zhu W, Zhang LG Nanoscale 28211933 Nanoscale 2017 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/28211933
3D Bioprinting for Organ Regeneration. Cui H, Nowicki M, Fisher JP, Zhang LG Advanced healthcare materials 27995751 Adv Healthc Mater 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27995751
Simulated Body Fluid Nucleation of Three-Dimensional Printed Elastomeric Scaffolds for Enhanced Osteogenesis. Castro NJ, Tan WN, Shen C, Zhang LG Tissue engineering. Part A 27298115 Tissue Eng Part A 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27298115
Photolithographic-stereolithographic-tandem fabrication of 4D smart scaffolds for improved stem cell cardiomyogenic differentiation. Miao S, Cui H, Nowicki M, Lee SJ, Almeida J, Zhou X, Zhu W, Yao X, Masood F, Plesniak MW, Mohiuddin M, Zhang LG Biofabrication 29651999 Biofabrication 2018 May 2 https://www.ncbi.nlm.nih.gov/pubmed/29651999
Bio-Based Polymers for 3D Printing of Bioscaffolds. Yang E, Miao S, Zhong J, Zhang Z, Mills DK, Zhang LG Polymer reviews (Philadelphia, Pa.) 30911289 Polym Rev (Phila Pa) 2018 https://www.ncbi.nlm.nih.gov/pubmed/30911289
Integrating three-dimensional printing and nanotechnology for musculoskeletal regeneration. Nowicki M, Castro NJ, Rao R, Plesniak M, Zhang LG Nanotechnology 28762957 Nanotechnology 2017 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/28762957
4D anisotropic skeletal muscle tissue constructs fabricated by staircase effect strategy. Miao S, Nowicki M, Cui H, Lee SJ, Zhou X, Mills DK, Zhang LG Biofabrication 31026857 Biofabrication 2019 Jun 24 https://www.ncbi.nlm.nih.gov/pubmed/31026857
3D bioprinting for cardiovascular regeneration and pharmacology. Cui H, Miao S, Esworthy T, Zhou X, Lee SJ, Liu C, Yu ZX, Fisher JP, Mohiuddin M, Zhang LG Advanced drug delivery reviews 30053441 Adv Drug Deliv Rev 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/30053441
Advanced 4D Bioprinting Technologies for Brain Tissue Modeling and Study. Esworthy TJ, Miao S, Lee SJ, Zhou X, Cui H, Zuo YY, Zhang LG International journal of smart and nano materials 32864037 Int J Smart Nano Mater 2019 https://www.ncbi.nlm.nih.gov/pubmed/32864037
3D Printed Stretchable Tactile Sensors. Guo SZ, Qiu K, Meng F, Park SH, McAlpine MC Advanced materials (Deerfield Beach, Fla.) 28474793 Adv Mater 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28474793
3D Printed Electrically-Driven Soft Actuators. Haghiashtiani G, Habtour E, Park SH, Gardea F, McAlpine MC Extreme Mechanics Letters 32596434 Extreme Mech Lett 2018 May https://www.ncbi.nlm.nih.gov/pubmed/32596434
3D printed deformable sensors. Zhu Z, Park HS, McAlpine MC Science advances 32596461 Sci Adv 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32596461
The Role of Nanoparticle Design in Determining Analytical Performance of Lateral Flow Immunoassays. Zhan L, Guo SZ, Song F, Gong Y, Xu F, Boulware DR, McAlpine MC, Chan WCW, Bischof JC Nano letters 29120648 Nano Lett 2017 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/29120648
3D Printed Functional and Biological Materials on Moving Freeform Surfaces. Zhu Z, Guo SZ, Hirdler T, Eide C, Fan X, Tolar J, McAlpine MC Advanced materials (Deerfield Beach, Fla.) 29691902 Adv Mater 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29691902
3D Printed Bionic Nanodevices. Kong YL, Gupta MK, Johnson BN, McAlpine MC Nano today 27617026 Nano Today 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27617026
3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments. Meng F, Meyer CM, Joung D, Vallera DA, McAlpine MC, Panoskaltsis-Mortari A Advanced materials (Deerfield Beach, Fla.) 30663123 Adv Mater 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30663123
3D Printed Programmable Release Capsules. Gupta MK, Meng F, Johnson BN, Kong YL, Tian L, Yeh YW, Masters N, Singamaneni S, McAlpine MC Nano letters 26042472 Nano Lett 2015 Aug 12 https://www.ncbi.nlm.nih.gov/pubmed/26042472
3D printed self-supporting elastomeric structures for multifunctional microfluidics. Su R, Wen J, Su Q, Wiederoder MS, Koester SJ, Uzarski JR, McAlpine MC Science advances 33036980 Sci Adv 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/33036980
3D Printed Neural Regeneration Devices. Joung D, Lavoie NS, Guo SZ, Park SH, Parr AM, McAlpine MC Advanced functional materials 32038121 Adv Funct Mater 2020 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/32038121
In Situ Expansion, Differentiation, and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid. Kupfer ME, Lin WH, Ravikumar V, Qiu K, Wang L, Gao L, Bhuiyan DB, Lenz M, Ai J, Mahutga RR, Townsend D, Zhang J, McAlpine MC, Tolkacheva EG, Ogle BM Circulation research 32228120 Circ Res 2020 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/32228120
3D Printed Polymer Photodetectors. Park SH, Su R, Jeong J, Guo SZ, Qiu K, Joung D, Meng F, McAlpine MC Advanced materials (Deerfield Beach, Fla.) 30151842 Adv Mater 2018 Aug 28 https://www.ncbi.nlm.nih.gov/pubmed/30151842
3D Printed Organ Models with Physical Properties of Tissue and Integrated Sensors. Qiu K, Zhao Z, Haghiashtiani G, Guo SZ, He M, Su R, Zhu Z, Bhuiyan DB, Murugan P, Meng F, Park SH, Chu CC, Ogle BM, Saltzman DA, Konety BR, Sweet RM, McAlpine MC Advanced materials technologies 29608202 Adv Mater Technol 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29608202
3D Printed Stem-Cell Derived Neural Progenitors Generate Spinal Cord Scaffolds. Joung D, Truong V, Neitzke CC, Guo SZ, Walsh PJ, Monat JR, Meng F, Park SH, Dutton JR, Parr AM, McAlpine MC Advanced functional materials 32595422 Adv Funct Mater 2018 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/32595422
3D Printed Organ Models for Surgical Applications. Qiu K, Haghiashtiani G, McAlpine MC Annual review of analytical chemistry (Palo Alto, Calif.) 29589961 Annu Rev Anal Chem (Palo Alto Calif) 2018 Jun 12 https://www.ncbi.nlm.nih.gov/pubmed/29589961
Corrigendum to "3D printed bionic nanodevices" [Nano Today 11 (2016) 330-350]. Kong YL, Gupta MK, Johnson BN, McAlpine MC Nano today 31186673 Nano Today 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/31186673
3D printed patient-specific aortic root models with internal sensors for minimally invasive applications. Haghiashtiani G, Qiu K, Zhingre Sanchez JD, Fuenning ZJ, Nair P, Ahlberg SE, Iaizzo PA, McAlpine MC Science advances 32923641 Sci Adv 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32923641
3D Printed Skin-Interfaced UV-Visible Hybrid Photodetectors. Ouyang X, Su R, Ng DWH, Han G, Pearson DR, McAlpine MC Advanced science (Weinheim, Baden-Wurttemberg, Germany) 35818683 Adv Sci (Weinh) 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35818683
3D-printed flexible organic light-emitting diode displays. Su R, Park SH, Ouyang X, Ahn SI, McAlpine MC Science advances 34995118 Sci Adv 2022 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/34995118
Conduction Cooling and Plasmonic Heating Dramatically Increase Droplet Vitrification Volumes for Cell Cryopreservation. Zhan L, Guo SZ, Kangas J, Shao Q, Shiao M, Khosla K, Low WC, McAlpine MC, Bischof J Advanced science (Weinheim, Baden-Wurttemberg, Germany) 34141523 Adv Sci (Weinh) 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34141523
The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits. Gardner BM, Chowdhury S, Lander GC, Martin A Journal of molecular biology 25659908 J Mol Biol 2015 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/25659908
Unique Structural Features of the Mitochondrial AAA+ Protease AFG3L2 Reveal the Molecular Basis for Activity in Health and Disease. Puchades C, Ding B, Song A, Wiseman RL, Lander GC, Glynn SE Molecular cell 31327635 Mol Cell 2019 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/31327635
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing. Fribourgh JL, Srivastava A, Sandate CR, Michael AK, Hsu PL, Rakers C, Nguyen LT, Torgrimson MR, Parico GCG, Tripathi S, Zheng N, Lander GC, Hirota T, Tama F, Partch CL eLife 32101164 Elife 2020 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/32101164
An allosteric network in spastin couples multiple activities required for microtubule severing. Sandate CR, Szyk A, Zehr EA, Lander GC, Roll-Mecak A Nature structural & molecular biology 31285604 Nat Struct Mol Biol 2019 Aug https://www.ncbi.nlm.nih.gov/pubmed/31285604
Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3. Hirschi M, Herzik MA Jr, Wie J, Suo Y, Borschel WF, Ren D, Lander GC, Lee SY Nature 29019979 Nature 2017 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/29019979
Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases. Garnham CP, Vemu A, Wilson-Kubalek EM, Yu I, Szyk A, Lander GC, Milligan RA, Roll-Mecak A Cell 25959773 Cell 2015 May 21 https://www.ncbi.nlm.nih.gov/pubmed/25959773
Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition. Dambacher CM, Worden EJ, Herzik MA, Martin A, Lander GC eLife 26744777 Elife 2016 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/26744777
Site-specific labeling of proteins for electron microscopy. Dambacher CM, Lander GC Journal of structural biology 26409249 J Struct Biol 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26409249
Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome. Bashore C, Dambacher CM, Goodall EA, Matyskiela ME, Lander GC, Martin A Nature structural & molecular biology 26301997 Nat Struct Mol Biol 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26301997
A guided approach for subtomogram averaging of challenging macromolecular assemblies. Basanta B, Chowdhury S, Lander GC, Grotjahn DA Journal of structural biology: X 33319208 J Struct Biol X 2020 https://www.ncbi.nlm.nih.gov/pubmed/33319208
The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading. Gardner BM, Castanzo DT, Chowdhury S, Stjepanovic G, Stefely MS, Hurley JH, Lander GC, Martin A Nature communications 29321502 Nat Commun 2018 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/29321502
The rod-shaped ATG2A-WIPI4 complex tethers membranes in vitro. Otomo T, Chowdhury S, Lander GC Contact (Thousand Oaks (Ventura County, Calif.)) 30766969 Contact (Thousand Oaks) 2018 Jan-Dec https://www.ncbi.nlm.nih.gov/pubmed/30766969
A Multi-model Approach to Assessing Local and Global Cryo-EM Map Quality. Herzik MA Jr, Fraser JS, Lander GC Structure (London, England : 1993) 30449687 Structure 2019 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/30449687
Substrate-engaged 26S proteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. de la Peña AH, Goodall EA, Gates SN, Lander GC, Martin A Science (New York, N.Y.) 30309908 Science 2018 Nov 30 https://www.ncbi.nlm.nih.gov/pubmed/30309908
Setting the dynein motor in motion: New insights from electron tomography. Grotjahn DA, Lander GC The Journal of biological chemistry 31285262 J Biol Chem 2019 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/31285262
Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex. Chowdhury S, Otomo C, Leitner A, Ohashi K, Aebersold R, Lander GC, Otomo T Proceedings of the National Academy of Sciences of the United States of America 30185561 Proc Natl Acad Sci U S A 2018 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/30185561
AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex. Hirschi M, Lu WT, Santiago-Frangos A, Wilkinson R, Golden SM, Davidson AR, Lander GC, Wiedenheft B Nature communications 32483187 Nat Commun 2020 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/32483187
Structural organization of the dynein-dynactin complex bound to microtubules. Chowdhury S, Ketcham SA, Schroer TA, Lander GC Nature structural & molecular biology 25751425 Nat Struct Mol Biol 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25751425
Structural basis for distinct operational modes and protease activation in AAA+ protease Lon. Shin M, Puchades C, Asmita A, Puri N, Adjei E, Wiseman RL, Karzai AW, Lander GC Science advances 32490208 Sci Adv 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32490208
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel. Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY Nature communications 31431622 Nat Commun 2019 Aug 20 https://www.ncbi.nlm.nih.gov/pubmed/31431622
The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer. Chen KC, Qu S, Chowdhury S, Noxon IC, Schonhoft JD, Plate L, Powers ET, Kelly JW, Lander GC, Wiseman RL The EMBO journal 28655754 EMBO J 2017 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/28655754
Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry. Rollins MF, Chowdhury S, Carter J, Golden SM, Miettinen HM, Santiago-Frangos A, Faith D, Lawrence CM, Lander GC, Wiedenheft B Molecular cell 30872121 Mol Cell 2019 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/30872121
Isolation of yeast complex IV in native lipid nanodiscs. Smirnova IA, Sjöstrand D, Li F, Björck M, Schäfer J, Östbye H, Högbom M, von Ballmoos C, Lander GC, Ädelroth P, Brzezinski P Biochimica et biophysica acta 27620332 Biochim Biophys Acta 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27620332
Cryo-EM structure of a mitochondrial calcium uniporter. Yoo J, Wu M, Yin Y, Herzik MA Jr, Lander GC, Lee SY Science (New York, N.Y.) 29954988 Science 2018 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/29954988
Conformational ensemble of the human TRPV3 ion channel. Zubcevic L, Herzik MA Jr, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY Nature communications 30429472 Nat Commun 2018 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/30429472
Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing. Puchades C, Rampello AJ, Shin M, Giuliano CJ, Wiseman RL, Glynn SE, Lander GC Science (New York, N.Y.) 29097521 Science 2017 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/29097521
The molecular principles governing the activity and functional diversity of AAA+ proteins. Puchades C, Sandate CR, Lander GC Nature reviews. Molecular cell biology 31754261 Nat Rev Mol Cell Biol 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31754261
Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility. Grotjahn DA, Chowdhury S, Xu Y, McKenney RJ, Schroer TA, Lander GC Nature structural & molecular biology 29416113 Nat Struct Mol Biol 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29416113
High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM. Herzik MA Jr, Wu M, Lander GC Nature communications 30833564 Nat Commun 2019 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/30833564
Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity. Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B Proceedings of the National Academy of Sciences of the United States of America 28438998 Proc Natl Acad Sci U S A 2017 Jun 27 https://www.ncbi.nlm.nih.gov/pubmed/28438998
Achieving better-than-3-Å resolution by single-particle cryo-EM at 200 keV. Herzik MA Jr, Wu M, Lander GC Nature methods 28991891 Nat Methods 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28991891
Exploring applications of crowdsourcing to cryo-EM. Bruggemann J, Lander GC, Su AI Journal of structural biology 29486249 J Struct Biol 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29486249
DNA-Assembled Core-Satellite Upconverting-Metal-Organic Framework Nanoparticle Superstructures for Efficient Photodynamic Therapy. He L, Brasino M, Mao C, Cho S, Park W, Goodwin AP, Cha JN Small (Weinheim an der Bergstrasse, Germany) 28481463 Small 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28481463
Depolymerizable Poly(O-vinyl carbamate-alt-sulfones) as Customizable Macromolecular Scaffolds for Mucosal Drug Delivery. Kumar K, Castaño EJ, Weidner AR, Yildirim A, Goodwin AP ACS macro letters 28480130 ACS Macro Lett 2016 May 17 https://www.ncbi.nlm.nih.gov/pubmed/28480130
Understanding Acoustic Cavitation Initiation by Porous Nanoparticles: Toward Nanoscale Agents for Ultrasound Imaging and Therapy. Yildirim A, Chattaraj R, Blum NT, Goodwin AP Chemistry of materials : a publication of the American Chemical Society 28484307 Chem Mater 2016 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/28484307
TiO(2)-Capped Gold Nanorods for Plasmon-Enhanced Production of Reactive Oxygen Species and Photothermal Delivery of Chemotherapeutic Agents. He L, Mao C, Brasino M, Harguindey A, Park W, Goodwin AP, Cha JN ACS applied materials & interfaces 30044085 ACS Appl Mater Interfaces 2018 Aug 22 https://www.ncbi.nlm.nih.gov/pubmed/30044085
Temperature-Responsive Hydrophobic Silica Nanoparticle Ultrasound Contrast Agents Directed by Phospholipid Phase Behavior. Blum NT, Yildirim A, Gyorkos C, Shi D, Cai A, Chattaraj R, Goodwin AP ACS applied materials & interfaces 31012297 ACS Appl Mater Interfaces 2019 May 1 https://www.ncbi.nlm.nih.gov/pubmed/31012297
Enzymes Photo-Cross-Linked to Live Cell Receptors Retain Activity and EGFR Inhibition after Both Internalization and Recycling. Roy S, Brasino M, Beirne JM, Harguindey A, Chapnick DA, Liu X, Cha JN, Goodwin AP Bioconjugate chemistry 31840981 Bioconjug Chem 2020 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/31840981
Phospholipid Capped Mesoporous Nanoparticles for Targeted High Intensity Focused Ultrasound Ablation. Yildirim A, Chattaraj R, Blum NT, Shi D, Kumar K, Goodwin AP Advanced healthcare materials 28699308 Adv Healthc Mater 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/28699308
Selective Vaporization of Superheated Nanodroplets for Rapid, Sensitive, Acoustic Biosensing. Chattaraj R, Mohan P, Besmer JD, Goodwin AP Advanced healthcare materials 26084414 Adv Healthc Mater 2015 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/26084414
Anti-EGFR Affibodies with Site-Specific Photo-Cross-Linker Incorporation Show Both Directed Target-Specific Photoconjugation and Increased Retention in Tumors. Brasino M, Roy S, Erbse AH, He L, Mao C, Park W, Cha JN, Goodwin AP Journal of the American Chemical Society 30203972 J Am Chem Soc 2018 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/30203972
Light-Driven Catalytic Upgrading of Butanol in a Biohybrid Photoelectrochemical System. Harris AW, Yehezkeli O, Hafenstine GR, Goodwin AP, Cha JN ACS sustainable chemistry & engineering 33133786 ACS Sustain Chem Eng 2017 https://www.ncbi.nlm.nih.gov/pubmed/33133786
Conversion of Ethanol to 2-Ethylhexenal at Ambient Conditions Using Tandem, Biphasic Catalysis. Hafenstine GR, Harris AW, Ma K, Cha JN, Goodwin AP ACS sustainable chemistry & engineering 33224638 ACS Sustain Chem Eng 2017 https://www.ncbi.nlm.nih.gov/pubmed/33224638
Nanoparticles Formed by Acoustic Destruction of Microbubbles and Their Utilization for Imaging and Effects on Therapy by High Intensity Focused Ultrasound. Blum NT, Yildirim A, Chattaraj R, Goodwin AP Theranostics 28255360 Theranostics 2017 https://www.ncbi.nlm.nih.gov/pubmed/28255360
Surface-Templated Nanobubbles Protect Proteins from Surface-Mediated Denaturation. Bull DS, Kienle DF, Chaparro Sosa AF, Nelson N, Roy S, Cha JN, Schwartz DK, Kaar JL, Goodwin AP The journal of physical chemistry letters 31067058 J Phys Chem Lett 2019 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/31067058
Contact Line Pinning Is Not Required for Nanobubble Stability on Copolymer Brushes. Bull DS, Nelson N, Konetski D, Bowman CN, Schwartz DK, Goodwin AP The journal of physical chemistry letters 30010342 J Phys Chem Lett 2018 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/30010342
Phospholipid-Coated Hydrophobic Mesoporous Silica Nanoparticles Enhance Thrombectomy by High-Intensity Focused Ultrasound with Low Production of Embolism-Inducing Clot Debris. Blum NT, Gyorkos CM, Narowetz SJ, Mueller EN, Goodwin AP ACS applied materials & interfaces 31556582 ACS Appl Mater Interfaces 2019 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/31556582
Catalytic Upgrading in Bacteria-Compatible Conditions via a Biocompatible Aldol Condensation. Domaille DW, Hafenstine GR, Greer MA, Goodwin AP, Cha JN ACS sustainable chemistry & engineering 28480149 ACS Sustain Chem Eng 2016 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/28480149
Phase Behavior of Mixed Lipid Monolayers on Perfluorocarbon Nanoemulsions and its Effect on Acoustic Contrast. Chattaraj R, Goldscheitter GM, Yildirim A, Goodwin AP RSC advances 28603605 RSC Adv 2016 Dec 4 https://www.ncbi.nlm.nih.gov/pubmed/28603605
Stable Encapsulation of Air in Mesoporous Silica Nanoparticles: Fluorocarbon-Free Nanoscale Ultrasound Contrast Agents. Yildirim A, Chattaraj R, Blum NT, Goldscheitter GM, Goodwin AP Advanced healthcare materials 26990167 Adv Healthc Mater 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/26990167
Polyacrylamide Hydrogels Produce Hydrogen Peroxide from Osmotic Swelling in Aqueous Media. Parameswar AV, Fitch KR, Bull DS, Duke VR, Goodwin AP Biomacromolecules 30052430 Biomacromolecules 2018 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/30052430
Nanoparticle-Mediated Acoustic Cavitation Enables High Intensity Focused Ultrasound Ablation Without Tissue Heating. Yildirim A, Shi D, Roy S, Blum NT, Chattaraj R, Cha JN, Goodwin AP ACS applied materials & interfaces 30339360 ACS Appl Mater Interfaces 2018 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/30339360
Design and Application of Stimulus-Responsive Droplets and Bubbles Stabilized by Phospholipid Monolayers. Chattaraj R, Blum NT, Goodwin AP Current opinion in colloid & interface science 31086500 Curr Opin Colloid Interface Sci 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/31086500
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Multicatalytic, Light-Driven Upgrading of Butanol to 2-Ethylhexenal and Hydrogen under Mild Aqueous Conditions. Hafenstine GR, Ma K, Harris AW, Yehezkeli O, Park E, Domaille DW, Cha JN, Goodwin AP ACS catalysis 33133753 ACS Catal 2017 https://www.ncbi.nlm.nih.gov/pubmed/33133753
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Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling. Gimple RC, Kidwell RL, Kim LJY, Sun T, Gromovsky AD, Wu Q, Wolf M, Lv D, Bhargava S, Jiang L, Prager BC, Wang X, Ye Q, Zhu Z, Zhang G, Dong Z, Zhao L, Lee D, Bi J, Sloan AE, Mischel PS, Brown JM, Cang H, Huan T, Mack SC, Xie Q, Rich JN Cancer discovery 31201181 Cancer Discov 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31201181
Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence. Liu S, Cao W, Niu Y, Luo J, Zhao Y, Hu Z, Zong C eLife 33983114 Elife 2021 May 13 https://www.ncbi.nlm.nih.gov/pubmed/33983114
Single-cell total-RNA profiling unveils regulatory hubs of transcription factors. Niu Y, Luo J, Zong C Nature communications 39009595 Nat Commun 2024 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/39009595
Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1. Jen HI, Hill MC, Tao L, Sheng K, Cao W, Zhang H, Yu HV, Llamas J, Zong C, Martin JF, Segil N, Groves AK eLife 31033441 Elife 2019 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/31033441
Droplet-based transcriptome profiling of individual synapses. Niu M, Cao W, Wang Y, Zhu Q, Luo J, Wang B, Zheng H, Weitz DA, Zong C Nature biotechnology 36646931 Nat Biotechnol 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/36646931
Fibroblast heterogeneity and its impact on extracellular matrix and immune landscape remodeling in cancer. Yamauchi M, Gibbons DL, Zong C, Fradette JJ, Bota-Rabassedas N, Kurie JM Matrix biology : journal of the International Society for Matrix Biology 32442601 Matrix Biol 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32442601
Single-cell Damagenome Profiling by Linear Copying and Splitting based Whole Genome Amplification (LCS-WGA). Niu Y, Zhu Q, Zong C Bio-protocol 35434195 Bio Protoc 2022 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/35434195
Single-cell damagenome profiling unveils vulnerable genes and functional pathways in human genome toward DNA damage. Zhu Q, Niu Y, Gundry M, Zong C Science advances 34215579 Sci Adv 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34215579
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Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch. Oakes BL, Nadler DC, Flamholz A, Fellmann C, Staahl BT, Doudna JA, Savage DF Nature biotechnology 27136077 Nat Biotechnol 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27136077
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Biofuel metabolic engineering with biosensors. Morgan SA, Nadler DC, Yokoo R, Savage DF Current opinion in chemical biology 27768949 Curr Opin Chem Biol 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27768949
Cas14: Big Advances from Small CRISPR Proteins. Savage DF Biochemistry 30740978 Biochemistry 2019 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/30740978
Imaging and three-dimensional reconstruction of chemical groups inside a protein complex using atomic force microscopy. Kim D, Sahin O Nature nanotechnology 25664622 Nat Nanotechnol 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25664622
Cellular nanoscale stiffness patterns governed by intracellular forces. Mandriota N, Friedsam C, Jones-Molina JA, Tatem KV, Ingber DE, Sahin O Nature materials 31209386 Nat Mater 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31209386
Calibration of T-shaped atomic force microscope cantilevers using the thermal noise method. Kim Y, Mandriota N, Goodnight D, Sahin O The Review of scientific instruments 32872926 Rev Sci Instrum 2020 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/32872926
Live-cell quantitative imaging of proteome degradation by stimulated Raman scattering. Shen Y, Xu F, Wei L, Hu F, Min W Angewandte Chemie (International ed. in English) 24737659 Angew Chem Int Ed Engl 2014 May 26 https://www.ncbi.nlm.nih.gov/pubmed/24737659
Operando and three-dimensional visualization of anion depletion and lithium growth by stimulated Raman scattering microscopy. Cheng Q, Wei L, Liu Z, Ni N, Sang Z, Zhu B, Xu W, Chen M, Miao Y, Chen LQ, Min W, Yang Y Nature communications 30061610 Nat Commun 2018 Jul 30 https://www.ncbi.nlm.nih.gov/pubmed/30061610
Optical imaging of metabolic dynamics in animals. Shi L, Zheng C, Shen Y, Chen Z, Silveira ES, Zhang L, Wei M, Liu C, de Sena-Tomas C, Targoff K, Min W Nature communications 30082908 Nat Commun 2018 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/30082908
Multicolor live-cell chemical imaging by isotopically edited alkyne vibrational palette. Chen Z, Paley DW, Wei L, Weisman AL, Friesner RA, Nuckolls C, Min W Journal of the American Chemical Society 24849912 J Am Chem Soc 2014 Jun 4 https://www.ncbi.nlm.nih.gov/pubmed/24849912
Spectral tracing of deuterium for imaging glucose metabolism. Zhang L, Shi L, Shen Y, Miao Y, Wei M, Qian N, Liu Y, Min W Nature biomedical engineering 31036888 Nat Biomed Eng 2019 May https://www.ncbi.nlm.nih.gov/pubmed/31036888
Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering. Long R, Zhang L, Shi L, Shen Y, Hu F, Zeng C, Min W Chemical communications (Cambridge, England) 29218356 Chem Commun (Camb) 2018 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/29218356
Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering. Wei L, Hu F, Shen Y, Chen Z, Yu Y, Lin CC, Wang MC, Min W Nature methods 24584195 Nat Methods 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24584195
Live-cell vibrational imaging of choline metabolites by stimulated Raman scattering coupled with isotope-based metabolic labeling. Hu F, Wei L, Zheng C, Shen Y, Min W The Analyst 24555181 Analyst 2014 May 21 https://www.ncbi.nlm.nih.gov/pubmed/24555181
Bioorthogonal chemical imaging of metabolic activities in live mammalian hippocampal tissues with stimulated Raman scattering. Hu F, Lamprecht MR, Wei L, Morrison B, Min W Scientific reports 28000773 Sci Rep 2016 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/28000773
Vibrational Imaging of Glucose Uptake Activity in Live Cells and Tissues by Stimulated Raman Scattering. Hu F, Chen Z, Zhang L, Shen Y, Wei L, Min W Angewandte Chemie (International ed. in English) 26207979 Angew Chem Int Ed Engl 2015 Aug 17 https://www.ncbi.nlm.nih.gov/pubmed/26207979
Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging. Hu F, Brucks SD, Lambert TH, Campos LM, Min W Chemical communications (Cambridge, England) 28474031 Chem Commun (Camb) 2017 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/28474031
Supermultiplexed optical imaging and barcoding with engineered polyynes. Hu F, Zeng C, Long R, Miao Y, Wei L, Xu Q, Min W Nature methods 29334378 Nat Methods 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29334378
Metabolic activity induces membrane phase separation in endoplasmic reticulum. Shen Y, Zhao Z, Zhang L, Shi L, Shahriar S, Chan RB, Di Paolo G, Min W Proceedings of the National Academy of Sciences of the United States of America 29196526 Proc Natl Acad Sci U S A 2017 Dec 19 https://www.ncbi.nlm.nih.gov/pubmed/29196526
Vibrational imaging of newly synthesized proteins in live cells by stimulated Raman scattering microscopy. Wei L, Yu Y, Shen Y, Wang MC, Min W Proceedings of the National Academy of Sciences of the United States of America 23798434 Proc Natl Acad Sci U S A 2013 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/23798434
Super-multiplex vibrational imaging. Wei L, Chen Z, Shi L, Long R, Anzalone AV, Zhang L, Hu F, Yuste R, Cornish VW, Min W Nature 28424513 Nature 2017 Apr 27 https://www.ncbi.nlm.nih.gov/pubmed/28424513
Imaging complex protein metabolism in live organisms by stimulated Raman scattering microscopy with isotope labeling. Wei L, Shen Y, Xu F, Hu F, Harrington JK, Targoff KL, Min W ACS chemical biology 25560305 ACS Chem Biol 2015 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/25560305
Bioorthogonal chemical imaging of metabolic changes during epithelial-mesenchymal transition of cancer cells by stimulated Raman scattering microscopy. Zhang L, Min W Journal of biomedical optics 29043713 J Biomed Opt 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/29043713
Applications of vibrational tags in biological imaging by Raman microscopy. Zhao Z, Shen Y, Hu F, Min W The Analyst 28875184 Analyst 2017 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/28875184
Electronic Preresonance Stimulated Raman Scattering Microscopy. Wei L, Min W The journal of physical chemistry letters 30001137 J Phys Chem Lett 2018 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/30001137
A ratiometric Raman probe for live-cell imaging of hydrogen sulfide in mitochondria by stimulated Raman scattering. Zeng C , Hu F , Long R , Min W The Analyst 30246812 Analyst 2018 Oct 8 https://www.ncbi.nlm.nih.gov/pubmed/30246812
Live-Cell Bioorthogonal Chemical Imaging: Stimulated Raman Scattering Microscopy of Vibrational Probes. Wei L, Hu F, Chen Z, Shen Y, Zhang L, Min W Accounts of chemical research 27486796 Acc Chem Res 2016 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/27486796
Reducing X-Ray Induced Oxidative Damages in Fibroblasts with Graphene Oxide. Qiao Y, Zhang P, Wang C, Ma L, Su M Nanomaterials (Basel, Switzerland) 25530873 Nanomaterials (Basel) 2014 https://www.ncbi.nlm.nih.gov/pubmed/25530873
Monte Carlo and analytic simulations in nanoparticle-enhanced radiation therapy. Paro AD, Hossain M, Webster TJ, Su M International journal of nanomedicine 27695329 Int J Nanomedicine 2016 https://www.ncbi.nlm.nih.gov/pubmed/27695329
Enhanced radiation therapy with internalized polyelectrolyte modified nanoparticles. Zhang P, Qiao Y, Wang C, Ma L, Su M Nanoscale 25032891 Nanoscale 2014 Sep 7 https://www.ncbi.nlm.nih.gov/pubmed/25032891
Whole slide imaging of circulating tumor cells captured on a capillary microchannel device. Zheng Y, Li Q, Hu W, Liao J, Zheng G, Su M Lab on a chip 31621763 Lab Chip 2019 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/31621763
Nanoparticle location and material dependent dose enhancement in X-ray radiation therapy. Hossain M, Su M The journal of physical chemistry. C, Nanomaterials and interfaces 23393610 J Phys Chem C Nanomater Interfaces 2012 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/23393610
Three-dimensional microtissues as an in vitro model for personalized radiation therapy. Qiu Y, Ning D, Zhang P, Curly S, Qiao Y, Ma L, Su M The Analyst 28812074 Analyst 2017 Sep 25 https://www.ncbi.nlm.nih.gov/pubmed/28812074
Multiplexed detection of molecular biomarkers with phase-change nanoparticles. Su M Nanomedicine (London, England) 23394155 Nanomedicine (Lond) 2013 Feb https://www.ncbi.nlm.nih.gov/pubmed/23394155
Surface charge controlled nucleoli selective staining with nanoscale carbon dots. Zhu Z, Li Q, Li P, Xun X, Zheng L, Ning D, Su M PloS one 31150413 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/31150413
Cationic surface modification of gold nanoparticles for enhanced cellular uptake and X-ray radiation therapy. Wang C, Sun A, Qiao Y, Zhang P, Ma L, Su M Journal of materials chemistry. B 26512323 J Mater Chem B 2015 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/26512323
Chip-scale alignment of long DNA nanofibers on a patterned self-assembled monolayer. Xia J, Su M Lab on a chip 28820213 Lab Chip 2017 Sep 26 https://www.ncbi.nlm.nih.gov/pubmed/28820213
Polydopamine Nanoparticles for Combined Chemo- and Photothermal Cancer Therapy. Zhu Z, Su M Nanomaterials (Basel, Switzerland) 28661423 Nanomaterials (Basel) 2017 Jun 29 https://www.ncbi.nlm.nih.gov/pubmed/28661423
A noncanonical polyamine from bacteria antagonizes animal mitochondrial function. Nauta KM, Gates DR, Weiland M, Mechan-Llontop ME, Wang X, Nguyen KP, Isaguirre C, Genjdar MR, Sheldon RD, Krawczyk CM, Burton NO bioRxiv : the preprint server for biology 38746390 bioRxiv 2025 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/38746390
An ultrathin membrane mediates tissue-specific morphogenesis and barrier function in a human kidney chip. Mou X, Shah J, Roye Y, Du C, Musah S Science advances 38838141 Sci Adv 2024 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/38838141
Kidney Disease Modeling with Organoids and Organs-on-Chips. Musah S, Bhattacharya R, Himmelfarb J Annual review of biomedical engineering 38424088 Annu Rev Biomed Eng 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38424088
Fenestrated Endothelial Cells across Organs: Insights into Kidney Function and Disease. Mou X, Leeman SM, Roye Y, Miller C, Musah S International journal of molecular sciences 39201792 Int J Mol Sci 2024 Aug 22 https://www.ncbi.nlm.nih.gov/pubmed/39201792
Unleashing the power of biomaterials to enhance organoid differentiation and function. Musah S, Arzaghi H Nature methods 39179910 Nat Methods 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/39179910
Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations. Bhattacharya R, Ward T, Kalejaiye TD, Mishra A, Leeman S, Arzaghi H, Seidman JG, Seidman CE, Musah S bioRxiv : the preprint server for biology 39211233 bioRxiv 2024 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/39211233
Editorial: Environmental rhythms at the host-microbe interface. Brooks JF, Heath-Heckman E, Kuang Z Frontiers in genetics 37811149 Front Genet 2023 https://www.ncbi.nlm.nih.gov/pubmed/37811149
HDAC3 integrates TGF-β and microbial cues to program tuft cell biogenesis and diurnal rhythms in mucosal immune surveillance. Zhang J, Wang G, Ma J, Duan Y, Sharma SA, Oladejo S, Ma X, Arellano G, Orchard RC, Reese TA, Kuang Z Science immunology 39331726 Sci Immunol 2024 Sep 27 https://www.ncbi.nlm.nih.gov/pubmed/39331726
Chemical interplay between gut microbiota and epigenetics: Implications in circadian biology. Sharma SA, Oladejo SO, Kuang Z Cell chemical biology 38776923 Cell Chem Biol 2025 Jan 16 https://www.ncbi.nlm.nih.gov/pubmed/38776923
A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan. Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, Markovski A, Sun S, Yao H, Sankaran VG, Gladyshev VN, Brooke RT, Horvath S, Griffith EC, Hrvatin S bioRxiv : the preprint server for biology 38585858 bioRxiv 2024 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/38585858
A torpor-like state in mice slows blood epigenetic aging and prolongs healthspan. Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, Markovski A, Sun S, Yao H, Sankaran VG, Gladyshev VN, Brooke RT, Horvath S, Griffith EC, Hrvatin S Nature aging 40055478 Nat Aging 2025 Mar https://www.ncbi.nlm.nih.gov/pubmed/40055478
Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death. Lam B, Kajderowicz KM, Keys HR, Roessler JM, Frenkel EM, Kirkland A, Bisht P, El-Brolosy MA, Jaenisch R, Bell GW, Weissman JS, Griffith EC, Hrvatin S bioRxiv : the preprint server for biology 39091747 bioRxiv 2024 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/39091747
Building a kidney tree: Functional collecting duct from human pluripotent stem cells. Li Z, Lindström NO Developmental cell 36220079 Dev Cell 2022 Oct 10 https://www.ncbi.nlm.nih.gov/pubmed/36220079
Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids. Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, Zhang CC, Schreiber ME, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Lindström NO, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, McMahon AP, Li Z bioRxiv : the preprint server for biology 37293038 bioRxiv 2023 May 25 https://www.ncbi.nlm.nih.gov/pubmed/37293038
Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease. Huang B, Zeng Z, Kim S, Fausto CC, Koppitch K, Li H, Li Z, Chen X, Guo J, Zhang CC, Ma T, Medina P, Schreiber ME, Xia MW, Vonk AC, Xiang T, Patel T, Li Y, Parvez RK, Der B, Chen JH, Liu Z, Thornton ME, Grubbs BH, Diao Y, Dou Y, Gnedeva K, Ying Q, Pastor-Soler NM, Fei T, Hallows KR, Lindström NO, McMahon AP, Li Z Cell stem cell 38692273 Cell Stem Cell 2024 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/38692273
Engineering multicellular living systems-a Keystone Symposia report. Cable J, Arlotta P, Parker KK, Hughes AJ, Goodwin K, Mummery CL, Kamm RD, Engle SJ, Tagle DA, Boj SF, Stanton AE, Morishita Y, Kemp ML, Norfleet DA, May EE, Lu A, Bashir R, Feinberg AW, Hull SM, Gonzalez AL, Blatchley MR, Montserrat Pulido N, Morizane R, McDevitt TC, Mishra D, Mulero-Russe A Annals of the New York Academy of Sciences 36177947 Ann N Y Acad Sci 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36177947
Kidney development to kidney organoids and back again. Gupta N, Morizane R Seminars in cell & developmental biology 34627669 Semin Cell Dev Biol 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/34627669
Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury. Ettou S, Jung YL, Miyoshi T, Jain D, Hiratsuka K, Schumacher V, Taglienti ME, Morizane R, Park PJ, Kreidberg JA Science advances 32754639 Sci Adv 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32754639
Cryopreservation of human kidney organoids. Mashouf P, Tabibzadeh N, Kuraoka S, Oishi H, Morizane R Cellular and molecular life sciences : CMLS 39023560 Cell Mol Life Sci 2024 Jul 18 https://www.ncbi.nlm.nih.gov/pubmed/39023560
Kidney organoids in translational medicine: Disease modeling and regenerative medicine. Miyoshi T, Hiratsuka K, Saiz EG, Morizane R Developmental dynamics : an official publication of the American Association of Anatomists 30843293 Dev Dyn 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/30843293
3D proximal tubule-on-chip model derived from kidney organoids with improved drug uptake. Aceves JO, Heja S, Kobayashi K, Robinson SS, Miyoshi T, Matsumoto T, Schäffers OJM, Morizane R, Lewis JA Scientific reports 36056134 Sci Rep 2022 Sep 2 https://www.ncbi.nlm.nih.gov/pubmed/36056134
Advancements in therapeutic development: kidney organoids and organs on a chip. Tabibzadeh N, Morizane R Kidney international 38296026 Kidney Int 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38296026
Generation of glucocorticoid-producing cells derived from human pluripotent stem cells. Ruiz-Babot G, Eceiza A, Abollo-Jiménez F, Malyukov M, Carlone DL, Borges K, Da Costa AR, Qarin S, Matsumoto T, Morizane R, Skarnes WC, Ludwig B, Chapple PJ, Guasti L, Storr HL, Bornstein SR, Breault DT Cell reports methods 37924815 Cell Rep Methods 2023 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/37924815
Functional maturation of kidney organoid tubules: PIEZO1-mediated Ca(2+) signaling. Carrisoza-Gaytan R, Kroll KT, Hiratsuka K, Gupta NR, Morizane R, Lewis JA, Satlin LM American journal of physiology. Cell physiology 36745528 Am J Physiol Cell Physiol 2023 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/36745528
A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis. Yoon SH, Meyer MB, Arevalo C, Tekguc M, Zhang C, Wang JS, Castro Andrade CD, Strauss K, Sato T, Benkusky NA, Lee SM, Berdeaux R, Foretz M, Sundberg TB, Xavier RJ, Adelmann CH, Brooks DJ, Anselmo A, Sadreyev RI, Rosales IA, Fisher DE, Gupta N, Morizane R, Greka A, Pike JW, Mannstadt M, Wein MN The Journal of clinical investigation 36862513 J Clin Invest 2023 May 1 https://www.ncbi.nlm.nih.gov/pubmed/36862513
Strategies for Improving Vascularization in Kidney Organoids: A Review of Current Trends. Konoe R, Morizane R Biology 37106704 Biology (Basel) 2023 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/37106704
Advancing preclinical drug evaluation through automated 3D imaging for high-throughput screening with kidney organoids. Oishi H, Tabibzadeh N, Morizane R Biofabrication 38547531 Biofabrication 2024 Apr 8 https://www.ncbi.nlm.nih.gov/pubmed/38547531
The NIH Somatic Cell Genome Editing program. Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J, SCGE Consortium Nature 33828315 Nature 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33828315
3D kidney organoids for bench-to-bedside translation. Gupta N, Dilmen E, Morizane R Journal of molecular medicine (Berlin, Germany) 33034708 J Mol Med (Berl) 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33034708
Live functional assays reveal longitudinal maturation of transepithelial transport in kidney organoids. Rizki-Safitri A, Gupta N, Hiratsuka K, Kobayashi K, Zhang C, Ida K, Satlin LM, Morizane R Frontiers in cell and developmental biology 36046340 Front Cell Dev Biol 2022 https://www.ncbi.nlm.nih.gov/pubmed/36046340
Kidney organoids: a pioneering model for kidney diseases. Tekguc M, Gaal RCV, Uzel SGM, Gupta N, Riella LV, Lewis JA, Morizane R Translational research : the journal of laboratory and clinical medicine 35750295 Transl Res 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/35750295
Immune-infiltrated kidney organoid-on-chip model for assessing T cell bispecific antibodies. Kroll KT, Mata MM, Homan KA, Micallef V, Carpy A, Hiratsuka K, Morizane R, Moisan A, Gubler M, Walz AC, Marrer-Berger E, Lewis JA Proceedings of the National Academy of Sciences of the United States of America 37603766 Proc Natl Acad Sci U S A 2023 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/37603766
ATP/ADP biosensor organoids for drug nephrotoxicity assessment. Susa K, Kobayashi K, Galichon P, Matsumoto T, Tamura A, Hiratsuka K, Gupta NR, Yazdi IK, Bonventre JV, Morizane R Frontiers in cell and developmental biology 36936695 Front Cell Dev Biol 2023 https://www.ncbi.nlm.nih.gov/pubmed/36936695
Bioengineered Kidney Models: Methods and Functional Assessments. Rizki-Safitri A, Traitteur T, Morizane R Function (Oxford, England) 35330622 Function (Oxf) 2021 https://www.ncbi.nlm.nih.gov/pubmed/35330622
Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair. Gupta N, Matsumoto T, Hiratsuka K, Garcia Saiz E, Galichon P, Miyoshi T, Susa K, Tatsumoto N, Yamashita M, Morizane R Science translational medicine 35235339 Sci Transl Med 2022 Mar 2 https://www.ncbi.nlm.nih.gov/pubmed/35235339
Navigating the kidney organoid: insights into assessment and enhancement of nephron function. Tabibzadeh N, Satlin LM, Jain S, Morizane R American journal of physiology. Renal physiology 37767571 Am J Physiol Renal Physiol 2023 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/37767571
Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery. Hiratsuka K, Miyoshi T, Kroll KT, Gupta NR, Valerius MT, Ferrante T, Yamashita M, Lewis JA, Morizane R Science advances 36129975 Sci Adv 2022 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/36129975
Brain Defense of Glycemia in Health and Diabetes. Mirzadeh Z, Faber C Diabetes 39401393 Diabetes 2024 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/39401393
Leptin receptor neurons in the dorsomedial hypothalamus regulate diurnal patterns of feeding, locomotion, and metabolism. Faber CL, Deem JD, Phan BA, Doan TP, Ogimoto K, Mirzadeh Z, Schwartz MW, Morton GJ eLife 33527893 Elife 2021 Feb 2 https://www.ncbi.nlm.nih.gov/pubmed/33527893
Central Nervous System Control of Glucose Homeostasis: A Therapeutic Target for Type 2 Diabetes? Mirzadeh Z, Faber CL, Schwartz MW Annual review of pharmacology and toxicology 34990204 Annu Rev Pharmacol Toxicol 2022 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/34990204
Multiplexed single-cell analysis reveals prognostic and nonprognostic T cell types in human colorectal cancer. Masuda K, Kornberg A, Miller J, Lin S, Suek N, Botella T, Secener KA, Bacarella AM, Cheng L, Ingham M, Rosario V, Al-Mazrou AM, Lee-Kong SA, Kiran RP, Stoeckius M, Smibert P, Del Portillo A, Oberstein PE, Sims PA, Yan KS, Han A JCI insight 35192548 JCI Insight 2022 Apr 8 https://www.ncbi.nlm.nih.gov/pubmed/35192548
R-SPONDIN2(+) mesenchymal cells form the bud tip progenitor niche during human lung development. Hein RFC, Wu JH, Holloway EM, Frum T, Conchola AS, Tsai YH, Wu A, Fine AS, Miller AJ, Szenker-Ravi E, Yan KS, Kuo CJ, Glass I, Reversade B, Spence JR Developmental cell 35679862 Dev Cell 2022 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/35679862
Microbial-Dependent Recruitment of Immature Myeloid Cells Promotes Intestinal Regeneration. Jiang Z, Waterbury QT, Malagola E, Fu N, Kim W, Ochiai Y, Wu F, Guha C, Shawber CJ, Yan KS, Wang TC Cellular and molecular gastroenterology and hepatology 37898454 Cell Mol Gastroenterol Hepatol 2024 https://www.ncbi.nlm.nih.gov/pubmed/37898454
COVID-19 Gastrointestinal Symptoms and Attenuation of the Immune Response to SARS-CoV-2. Miller J, Yan KS Gastroenterology 33753106 Gastroenterology 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33753106
3D Organoids: An Untapped Platform for Studying Host-Microbiome Interactions in Esophageal Cancers. Flashner S, Yan KS, Nakagawa H Microorganisms 34835308 Microorganisms 2021 Oct 20 https://www.ncbi.nlm.nih.gov/pubmed/34835308
Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells. Capdevila C, Miller J, Cheng L, Kornberg A, George JJ, Lee H, Botella T, Moon CS, Murray JW, Lam S, Calderon RI, Malagola E, Whelan G, Lin CS, Han A, Wang TC, Sims PA, Yan KS Cell 38848677 Cell 2024 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/38848677
Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury. Malagola E, Vasciaveo A, Ochiai Y, Kim W, Zheng B, Zanella L, Wang ALE, Middelhoff M, Nienhüser H, Deng L, Wu F, Waterbury QT, Belin B, LaBella J, Zamechek LB, Wong MH, Li L, Guha C, Cheng CW, Yan KS, Califano A, Wang TC Cell 38848678 Cell 2024 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/38848678
Single-Cell Transcriptional Profiling of the Intestinal Epithelium. Capdevila C, Calderon RI, Bush EC, Sheldon-Collins K, Sims PA, Yan KS Methods in molecular biology (Clifton, N.J.) 32705639 Methods Mol Biol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32705639
Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration. Maan ZN, Rinkevich Y, Barrera J, Chen K, Henn D, Foster D, Bonham CA, Padmanabhan J, Sivaraj D, Duscher D, Hu M, Yan K, Januszyk M, Longaker MT, Weissman IL, Gurtner GC Journal of clinical medicine 34575372 J Clin Med 2021 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/34575372
Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids. Flashner S, Martin C, Matsuura N, Shimonosono M, Tomita Y, Morimoto M, Okolo O, Yu VX, Parikh AS, Klein-Szanto AJP, Yan K, Gabre JT, Lu C, Momen-Heravi F, Rustgi AK, Nakagawa H Journal of visualized experiments : JoVE 36622034 J Vis Exp 2022 Dec 23 https://www.ncbi.nlm.nih.gov/pubmed/36622034
Presentation of the Julius M. Friedenwald Medal to Timothy C. Wang, MD, AGAF. Abrams J, Camilleri M, Merchant J, Rustgi AK, Yan K Gastroenterology 35443933 Gastroenterology 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35443933
Single-Cell Studies of Intestinal Stem Cell Heterogeneity During Homeostasis and Regeneration. Norkin M, Capdevila C, Calderon RI, Su T, Trifas M, Ordóñez-Morán P, Yan KS Methods in molecular biology (Clifton, N.J.) 32705640 Methods Mol Biol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32705640
Cellular origins and lineage relationships of the intestinal epithelium. Capdevila C, Trifas M, Miller J, Anderson T, Sims PA, Yan KS American journal of physiology. Gastrointestinal and liver physiology 34431400 Am J Physiol Gastrointest Liver Physiol 2021 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/34431400
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease. Kornberg A, Botella T, Moon CS, Rao S, Gelbs J, Cheng L, Miller J, Bacarella AM, García-Vilas JA, Vargas J, Yu X, Krupska I, Bush E, Garcia-Carrasquillo R, Lebwohl B, Krishnareddy S, Lewis S, Green PHR, Bhagat G, Yan KS, Han A Science immunology 37450575 Sci Immunol 2023 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/37450575
Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope. Lovelace JW, Ma J, Yadav S, Chhabria K, Shen H, Pang Z, Qi T, Sehgal R, Zhang Y, Bali T, Vaissiere T, Tan S, Liu Y, Rumbaugh G, Ye L, Kleinfeld D, Stringer C, Augustine V Nature 37914931 Nature 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37914931
Xiphoid nucleus of the midline thalamus controls cold-induced food seeking. Lal NK, Le P, Aggarwal S, Zhang A, Wang K, Qi T, Pang Z, Yang D, Nudell V, Yeo GW, Banks AS, Ye L Nature 37587337 Nature 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/37587337
In situ identification of cellular drug targets in mammalian tissue. Pang Z, Schafroth MA, Ogasawara D, Wang Y, Nudell V, Lal NK, Yang D, Wang K, Herbst DM, Ha J, Guijas C, Blankman JL, Cravatt BF, Ye L Cell 35483372 Cell 2022 May 12 https://www.ncbi.nlm.nih.gov/pubmed/35483372
The Afferent Function of Adipose Innervation. Wang Y, Ye L Diabetes 38377447 Diabetes 2024 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/38377447
The role of somatosensory innervation of adipose tissues. Wang Y, Leung VH, Zhang Y, Nudell VS, Loud M, Servin-Vences MR, Yang D, Wang K, Moya-Garzon MD, Li VL, Long JZ, Patapoutian A, Ye L Nature 36045288 Nature 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/36045288
Brainstem Dbh(+) neurons control allergen-induced airway hyperreactivity. Su Y, Xu J, Zhu Z, Chin J, Xu L, Yu H, Nudell V, Dash B, Moya EA, Ye L, Nimmerjahn A, Sun X Nature 38987587 Nature 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38987587
Cortical Representations of Conspecific Sex Shape Social Behavior. Kingsbury L, Huang S, Raam T, Ye LS, Wei D, Hu RK, Ye L, Hong W Neuron 32663438 Neuron 2020 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/32663438
Acetylcholine-synthesizing macrophages in subcutaneous fat are regulated by β(2) -adrenergic signaling. Knights AJ, Liu S, Ma Y, Nudell VS, Perkey E, Sorensen MJ, Kennedy RT, Maillard I, Ye L, Jun H, Wu J The EMBO journal 34459015 EMBO J 2021 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/34459015
A protocol to visualize on-target specific drug binding in mammalian tissue with cellular resolution using tissue clearing and click chemistry. Pang Z, Ye L STAR protocols 36313539 STAR Protoc 2022 Dec 16 https://www.ncbi.nlm.nih.gov/pubmed/36313539
Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity. Yang D, Wang Y, Qi T, Zhang X, Shen L, Ma J, Pang Z, Lal NK, McClatchy DB, Seradj SH, Leung VH, Wang K, Xie Y, Polli FS, Maximov A, Gonzalez OC, de Lecea L, Cline HT, Augustine V, Yates JR 3rd, Ye L Neuron 38266644 Neuron 2024 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/38266644
TESOS: an integrated approach for uniform mesoscale imaging. Wang Y, Ye L Cell research 38168641 Cell Res 2024 Feb https://www.ncbi.nlm.nih.gov/pubmed/38168641
Xiphoid nucleus of the midline thalamus controls cold-induced food seeking. Lal NK, Le P, Aggarwal S, Zhang A, Wang K, Qi T, Pang Z, Yang D, Nudell V, Yeo GW, Banks AS, Ye L bioRxiv : the preprint server for biology 36993706 bioRxiv 2023 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/36993706
Somatosensory innervation of adipose tissues. Wang Y, Ye L Physiology & behavior 36965573 Physiol Behav 2023 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/36965573
A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation. Wang Y, Zhang Y, Leung V, Seradj SH, Sonmez U, Servin-Vences R, Lipomi D, Ye L, Patapoutian A bioRxiv : the preprint server for biology 39605632 bioRxiv 2024 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/39605632
HYBRiD: hydrogel-reinforced DISCO for clearing mammalian bodies. Nudell V, Wang Y, Pang Z, Lal NK, Huang M, Shaabani N, Kanim W, Teijaro J, Maximov A, Ye L Nature methods 35347322 Nat Methods 2022 Apr https://www.ncbi.nlm.nih.gov/pubmed/35347322
Illuminating spatial pharmacology with in situ drug imaging. Pang Z, Ye L Clinical and translational medicine 36030504 Clin Transl Med 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/36030504
Narrative engineering of the liver. Lee IS, Takebe T Current opinion in genetics & development 35700688 Curr Opin Genet Dev 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/35700688
Cellotype-phenotype associations using 'organoid villages'. Kimura M, Takebe T Trends in endocrinology and metabolism: TEM 38575442 Trends Endocrinol Metab 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38575442
Polygenic architecture informs potential vulnerability to drug-induced liver injury. Koido M, Kawakami E, Fukumura J, Noguchi Y, Ohori M, Nio Y, Nicoletti P, Aithal GP, Daly AK, Watkins PB, Anayama H, Dragan Y, Shinozawa T, Takebe T Nature medicine 32895570 Nat Med 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32895570
Human liver model systems in a dish. Thompson WL, Takebe T Development, growth & differentiation 33423319 Dev Growth Differ 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33423319
Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids. Miao Y, Tan C, Pek NM, Yu Z, Iwasawa K, Kechele DO, Sundaram N, Pastrana-Gomez V, Kishimoto K, Yang MC, Jiang C, Tchieu J, Whitsett JA, McCracken KW, Rottier RJ, Kotton DN, Helmrath MA, Wells JM, Takebe T, Zorn AM, Chen YW, Guo M, Gu M bioRxiv : the preprint server for biology 38370768 bioRxiv 2024 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/38370768
POLYseq: A poly(β-amino ester)-based vector for multifunctional cellular barcoding. Dunn A, Cai Y, Iwasawa K, Kimura M, Takebe T Stem cell reports 34450040 Stem Cell Reports 2021 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/34450040
Organoid transplant approaches for the liver. Reza HA, Okabe R, Takebe T Transplant international : official journal of the European Society for Organ Transplantation 34614263 Transpl Int 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34614263
En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH. Kimura M, Iguchi T, Iwasawa K, Dunn A, Thompson WL, Yoneyama Y, Chaturvedi P, Zorn AM, Wintzinger M, Quattrocelli M, Watanabe-Chailland M, Zhu G, Fujimoto M, Kumbaji M, Kodaka A, Gindin Y, Chung C, Myers RP, Subramanian GM, Hwa V, Takebe T Cell 36240780 Cell 2022 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/36240780
In vitro human cell-based models: What can they do and what are their limitations? Lutolf MP, Radisic M, Beekman J, Huh DD, Huch M, Turco MY, Tahmasebi Birgani ZN, Gao D, Yao R, Lin H, Takebe T Cell 39178827 Cell 2024 Aug 22 https://www.ncbi.nlm.nih.gov/pubmed/39178827
Inter-cellular mRNA Transfer Alters Human Pluripotent Stem Cell State. Yoneyama Y, Zhang RR, Kimura M, Cai Y, Adam M, Parameswaran S, Masaki H, Mizuno N, Bhadury J, Maezawa S, Ochiai H, Nakauchi H, Potter SS, Weirauch MT, Takebe T bioRxiv : the preprint server for biology 38979277 bioRxiv 2024 Jun 27 https://www.ncbi.nlm.nih.gov/pubmed/38979277
Eicosatetraynoic Acid Regulates Profibrotic Pathways in an Induced Pluripotent Stem Cell-Derived Macrophage-Human Intestinal Organoid Model of Crohn's Disease. Jurickova I, Dreskin BW, Angerman E, Bonkowski E, Nguyen J, Villarreal R, Tominaga K, Iwasawa K, Braun T, Takebe T, Helmrath MA, Haberman Y, Wells JM, Denson LA Journal of Crohn's & colitis 39212594 J Crohns Colitis 2025 Feb 4 https://www.ncbi.nlm.nih.gov/pubmed/39212594
Self-Assembled Generation of Multi-zonal Liver Organoids from Human Pluripotent Stem Cells. Al Reza H, Santangelo C, Al Reza A, Iwasawa K, Sachiko S, Glaser K, Bondoc A, Merola J, Takebe T bioRxiv : the preprint server for biology 39257824 bioRxiv 2024 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/39257824
Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells. Rezvani M, Lewis K, Quach S, Iwasawa K, Weihs J, Reza H, Cai Y, Kimura M, Zhang R, Milton Y, Chaturvedi P, Thorner K, Nayak RC, Munera JO, Kramer P, Davis B, Balamurugan A, Ait Ahmed Y, Finke M, Behncke RY, Guillot A, Haegerling R, Polansky J, Bufler P, Cancelas J, Wells J, Yoshimoto M, Takebe T bioRxiv : the preprint server for biology 39416072 bioRxiv 2024 Oct 12 https://www.ncbi.nlm.nih.gov/pubmed/39416072
Generation of multi-cellular human liver organoids from pluripotent stem cells. Thompson WL, Takebe T Methods in cell biology 32586449 Methods Cell Biol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32586449
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection. Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Murphy A, Iskhakova M, Fernando MB, Powell SK, Deans PJM, Javidfar B, Peter C, Møller R, Uhl SA, Garcia MF, Kimura M, Iwasawa K, Crary JF, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ Stem cell reports 33636110 Stem Cell Reports 2021 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/33636110
Fetal liver hematopoiesis: from development to delivery. Lewis K, Yoshimoto M, Takebe T Stem cell research & therapy 33597015 Stem Cell Res Ther 2021 Feb 17 https://www.ncbi.nlm.nih.gov/pubmed/33597015
The promise of human organoids in the digestive system. Funata M, Nio Y, Erion DM, Thompson WL, Takebe T Cell death and differentiation 33204011 Cell Death Differ 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33204011
Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Koike H, Iwasawa K, Ouchi R, Maezawa M, Kimura M, Kodaka A, Nishii S, Thompson WL, Takebe T Nature protocols 33432231 Nat Protoc 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33432231
High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids. Shinozawa T, Kimura M, Cai Y, Saiki N, Yoneyama Y, Ouchi R, Koike H, Maezawa M, Zhang RR, Dunn A, Ferguson A, Togo S, Lewis K, Thompson WL, Asai A, Takebe T Gastroenterology 33039464 Gastroenterology 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33039464
A Pillar and Perfusion Plate Platform for Robust Human Organoid Culture and Analysis. Kang SY, Kimura M, Shrestha S, Lewis P, Lee S, Cai Y, Joshi P, Acharya P, Liu J, Yang Y, Sanchez JG, Ayyagari S, Alsberg E, Wells JM, Takebe T, Lee MY Advanced healthcare materials 37616035 Adv Healthc Mater 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/37616035
Organogenesis in vitro. Iwasawa K, Takebe T Current opinion in cell biology 34352726 Curr Opin Cell Biol 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34352726
Synthesis and application of POLYseq for profiling human liver organoids. Dunn AW, Cai Y, Iwasawa K, Kimura M, Takebe T STAR protocols 34934958 STAR Protoc 2021 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/34934958
Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems. Kishimoto K, Iwasawa K, Sorel A, Ferran-Heredia C, Han L, Morimoto M, Wells JM, Takebe T, Zorn AM Nature protocols 35978039 Nat Protoc 2022 Nov https://www.ncbi.nlm.nih.gov/pubmed/35978039
Synthetic augmentation of bilirubin metabolism in human pluripotent stem cell-derived liver organoids. Reza HA, Farooqui Z, Reza AA, Conroy C, Iwasawa K, Ogura Y, Okita K, Osafune K, Takebe T Stem cell reports 37832542 Stem Cell Reports 2023 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/37832542
ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH. Liu YJ, Kimura M, Li X, Sulc J, Wang Q, Rodríguez-López S, Scantlebery AML, Strotjohann K, Gallart-Ayala H, Vijayakumar A, Myers RP, Ivanisevic J, Houtkooper RH, Subramanian GM, Takebe T, Auwerx J Journal of hepatology 39181211 J Hepatol 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39181211
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids. Marsee A, Roos FJM, Verstegen MMA, HPB Organoid Consortium, Gehart H, de Koning E, Lemaigre F, Forbes SJ, Peng WC, Huch M, Takebe T, Vallier L, Clevers H, van der Laan LJW, Spee B Cell stem cell 33961769 Cell Stem Cell 2021 May 6 https://www.ncbi.nlm.nih.gov/pubmed/33961769
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection. Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Iskhakova M, Fernando MB, Deans PJM, Powell SK, Javidfar B, Murphy A, Peter C, Møeller R, Garcia MF, Kimura M, Iwasawa K, Crary J, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ bioRxiv : the preprint server for biology 32995783 bioRxiv 2020 Sep 21 https://www.ncbi.nlm.nih.gov/pubmed/32995783
Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19. Kawakami E, Saiki N, Yoneyama Y, Moriya C, Maezawa M, Kawamura S, Kinebuchi A, Kono T, Funata M, Sakoda A, Kondo S, Ebihara T, Matsumoto H, Togami Y, Ogura H, Sugihara F, Okuzaki D, Kojima T, Deguchi S, Vallee S, McQuade S, Islam R, Natarajan M, Ishigaki H, Nakayama M, Nguyen CT, Kitagawa Y, Wu Y, Mori K, Hishiki T, Takasaki T, Itoh Y, Takayama K, Nio Y, Takebe T Cell stem cell 37802037 Cell Stem Cell 2023 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/37802037
Self-Organization of Sinusoidal Vessels in Pluripotent Stem Cell-derived Human Liver Bud Organoids. Saiki N, Nio Y, Yoneyama Y, Kawamura S, Iwasawa K, Kawakami E, Araki K, Fukumura J, Sakairi T, Kono T, Ohmura R, Koido M, Funata M, Thompson WL, Cruz-Encarnacion P, Chen YW, Takebe T bioRxiv : the preprint server for biology 39005378 bioRxiv 2024 Jul 4 https://www.ncbi.nlm.nih.gov/pubmed/39005378
Intercellular mRNA transfer alters the human pluripotent stem cell state. Yoneyama Y, Zhang RR, Maezawa M, Masaki H, Kimura M, Cai Y, Adam M, Parameswaran S, Mizuno N, Bhadury J, Maezawa S, Ochiai H, Nakauchi H, Potter SS, Weirauch MT, Takebe T Proceedings of the National Academy of Sciences of the United States of America 39841146 Proc Natl Acad Sci U S A 2025 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/39841146
Organoid-guided precision hepatology for metabolic liver disease. Osonoi S, Takebe T Journal of hepatology 38237864 J Hepatol 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38237864
Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids. Sheth M, Sharma M, Lehn M, Reza H, Takebe T, Takiar V, Wise-Draper T, Esfandiari L APL bioengineering 39092008 APL Bioeng 2024 Sep https://www.ncbi.nlm.nih.gov/pubmed/39092008
Autoreactivity in naïve human fetal B cells is associated with commensal bacteria recognition. Chen JW, Rice TA, Bannock JM, Bielecka AA, Strauss JD, Catanzaro JR, Wang H, Menard LC, Anolik JH, Palm NW, Meffre E Science (New York, N.Y.) 32675374 Science 2020 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/32675374
Within-host evolution of a gut pathobiont facilitates liver translocation. Yang Y, Nguyen M, Khetrapal V, Sonnert ND, Martin AL, Chen H, Kriegel MA, Palm NW Nature 35831502 Nature 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35831502
Small Molecule Metabolites at the Host-Microbiota Interface. Bishai JD, Palm NW Journal of immunology (Baltimore, Md. : 1950) 34544815 J Immunol 2021 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/34544815
Gut instincts in neuroimmunity from the eighteenth to twenty-first centuries. Nguyen M, Palm NW Seminars in immunopathology 35786740 Semin Immunopathol 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35786740
Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites. Cao Y, Oh J, Xue M, Huh WJ, Wang J, Gonzalez-Hernandez JA, Rice TA, Martin AL, Song D, Crawford JM, Herzon SB, Palm NW Science (New York, N.Y.) 36302024 Science 2022 Oct 28 https://www.ncbi.nlm.nih.gov/pubmed/36302024
Interspecies commensal interactions have nonlinear impacts on host immunity. Rice TA, Bielecka AA, Nguyen MT, Rosen CE, Song D, Sonnert ND, Yang Y, Cao Y, Khetrapal V, Catanzaro JR, Martin AL, Rashed SA, Leopold SR, Hao L, Yu X, van Dijk D, Ring AM, Flavell RA, de Zoete MR, Palm NW Cell host & microbe 35640610 Cell Host Microbe 2022 Jul 13 https://www.ncbi.nlm.nih.gov/pubmed/35640610
Highly multiplexed bioactivity screening reveals human and microbiota metabolome-GPCRome interactions. Chen H, Rosen CE, González-Hernández JA, Song D, Potempa J, Ring AM, Palm NW Cell 37321219 Cell 2023 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/37321219
Diagnosis, Education, and Care of Patients with APOL1-Associated Nephropathy: A Delphi Consensus and Systematic Review. Freedman BI, Burke W, Divers J, Eberhard L, Gadegbeku CA, Gbadegesin R, Hall ME, Jones-Smith T, Knight R, Kopp JB, Kovesdy CP, Norris KC, Olabisi OA, Roberts GV, Sedor JR, Blacksher E Journal of the American Society of Nephrology : JASN 33853887 J Am Soc Nephrol 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/33853887
Kidney Disease-Associated APOL1 Variants Have Dose-Dependent, Dominant Toxic Gain-of-Function. Datta S, Kataria R, Zhang JY, Moore S, Petitpas K, Mohamed A, Zahler N, Pollak MR, Olabisi OA Journal of the American Society of Nephrology : JASN 32675303 J Am Soc Nephrol 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32675303
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Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness. Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, Wu JC, Moon RT, Si Dong PD, Karakikes I, Cashman JR, Mercola M Cell chemical biology 33503403 Cell Chem Biol 2021 May 20 https://www.ncbi.nlm.nih.gov/pubmed/33503403
KPC and NDM-1 genes in related Enterobacteriaceae strains and plasmids from Pakistan and the United States. Pesesky MW, Hussain T, Wallace M, Wang B, Andleeb S, Burnham CA, Dantas G Emerging infectious diseases 25988236 Emerg Infect Dis 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25988236
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Characterization of Wild and Captive Baboon Gut Microbiota and Their Antibiotic Resistomes. Tsukayama P, Boolchandani M, Patel S, Pehrsson EC, Gibson MK, Chiou KL, Jolly CJ, Rogers J, Phillips-Conroy JE, Dantas G mSystems 29963641 mSystems 2018 May-Jun https://www.ncbi.nlm.nih.gov/pubmed/29963641
Longitudinal analysis of microbial interaction between humans and the indoor environment. Lax S, Smith DP, Hampton-Marcell J, Owens SM, Handley KM, Scott NM, Gibbons SM, Larsen P, Shogan BD, Weiss S, Metcalf JL, Ursell LK, Vázquez-Baeza Y, Van Treuren W, Hasan NA, Gibson MK, Colwell R, Dantas G, Knight R, Gilbert JA Science (New York, N.Y.) 25170151 Science 2014 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/25170151
Bacterial phylogeny structures soil resistomes across habitats. Forsberg KJ, Patel S, Gibson MK, Lauber CL, Knight R, Fierer N, Dantas G Nature 24847883 Nature 2014 May 29 https://www.ncbi.nlm.nih.gov/pubmed/24847883
Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms. Sun J, Liao XP, D'Souza AW, Boolchandani M, Li SH, Cheng K, Luis Martínez J, Li L, Feng YJ, Fang LX, Huang T, Xia J, Yu Y, Zhou YF, Sun YX, Deng XB, Zeng ZL, Jiang HX, Fang BH, Tang YZ, Lian XL, Zhang RM, Fang ZW, Yan QL, Dantas G, Liu YH Nature communications 32188862 Nat Commun 2020 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/32188862
Prairie plants harbor distinct and beneficial root-endophytic bacterial communities. Adu-Oppong B, Mangan SA, Stein C, Catano CP, Myers JA, Dantas G PloS one 32574172 PLoS One 2020 https://www.ncbi.nlm.nih.gov/pubmed/32574172
Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes. Adu-Oppong B, Gasparrini AJ, Dantas G Annals of the New York Academy of Sciences 27768825 Ann N Y Acad Sci 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27768825
The microbiome and resistome of chimpanzees, gorillas, and humans across host lifestyle and geography. Campbell TP, Sun X, Patel VH, Sanz C, Morgan D, Dantas G The ISME journal 32203121 ISME J 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32203121
The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes. Forsberg KJ, Patel S, Wencewicz TA, Dantas G Chemistry & biology 26097034 Chem Biol 2015 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/26097034
Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria. Crofts TS, Wang B, Spivak A, Gianoulis TA, Forsberg KJ, Gibson MK, Johnsky LA, Broomall SM, Rosenzweig CN, Skowronski EW, Gibbons HS, Sommer MOA, Dantas G Genome announcements 28798166 Genome Announc 2017 Aug 10 https://www.ncbi.nlm.nih.gov/pubmed/28798166
Functional mining of novel terpene synthases from metagenomes. Kwak S, Crook N, Yoneda A, Ahn N, Ning J, Cheng J, Dantas G Biotechnology for biofuels and bioproducts 36209178 Biotechnol Biofuels Bioprod 2022 Oct 8 https://www.ncbi.nlm.nih.gov/pubmed/36209178
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The yin and yang of bacterial resilience in the human gut microbiota. Gibson MK, Pesesky MW, Dantas G Journal of molecular biology 24911583 J Mol Biol 2014 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/24911583
Evaluation of Machine Learning and Rules-Based Approaches for Predicting Antimicrobial Resistance Profiles in Gram-negative Bacilli from Whole Genome Sequence Data. Pesesky MW, Hussain T, Wallace M, Patel S, Andleeb S, Burnham CD, Dantas G Frontiers in microbiology 27965630 Front Microbiol 2016 https://www.ncbi.nlm.nih.gov/pubmed/27965630
The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation. Langdon A, Crook N, Dantas G Genome medicine 27074706 Genome Med 2016 Apr 13 https://www.ncbi.nlm.nih.gov/pubmed/27074706
Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut. Crook N, Ferreiro A, Gasparrini AJ, Pesesky MW, Gibson MK, Wang B, Sun X, Condiotte Z, Dobrowolski S, Peterson D, Dantas G Cell host & microbe 30926240 Cell Host Microbe 2019 Apr 10 https://www.ncbi.nlm.nih.gov/pubmed/30926240
Discovery and Characterization of a Nitroreductase Capable of Conferring Bacterial Resistance to Chloramphenicol. Crofts TS, Sontha P, King AO, Wang B, Biddy BA, Zanolli N, Gaumnitz J, Dantas G Cell chemical biology 30799223 Cell Chem Biol 2019 Apr 18 https://www.ncbi.nlm.nih.gov/pubmed/30799223
The microbiome of uncontacted Amerindians. Clemente JC, Pehrsson EC, Blaser MJ, Sandhu K, Gao Z, Wang B, Magris M, Hidalgo G, Contreras M, Noya-Alarcón Ó, Lander O, McDonald J, Cox M, Walter J, Oh PL, Ruiz JF, Rodriguez S, Shen N, Song SJ, Metcalf J, Knight R, Dantas G, Dominguez-Bello MG Science advances 26229982 Sci Adv 2015 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/26229982
Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs. Pehrsson EC, Forsberg KJ, Gibson MK, Ahmadi S, Dantas G Frontiers in microbiology 23760651 Front Microbiol 2013 https://www.ncbi.nlm.nih.gov/pubmed/23760651
High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED. Kaminski J, Gibson MK, Franzosa EA, Segata N, Dantas G, Huttenhower C PLoS computational biology 26682918 PLoS Comput Biol 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26682918
Identification of Genes Conferring Tolerance to Lignocellulose-Derived Inhibitors by Functional Selections in Soil Metagenomes. Forsberg KJ, Patel S, Witt E, Wang B, Ellison TD, Dantas G Applied and environmental microbiology 26546427 Appl Environ Microbiol 2016 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/26546427
Next-generation approaches to understand and combat the antibiotic resistome. Crofts TS, Gasparrini AJ, Dantas G Nature reviews. Microbiology 28392565 Nat Rev Microbiol 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28392565
Functional Metagenomics to Study Antibiotic Resistance. Mahmud B, Boolchandani M, Patel S, Dantas G Methods in molecular biology (Clifton, N.J.) 36445596 Methods Mol Biol 2023 https://www.ncbi.nlm.nih.gov/pubmed/36445596
Shared strategies for β-lactam catabolism in the soil microbiome. Crofts TS, Wang B, Spivak A, Gianoulis TA, Forsberg KJ, Gibson MK, Johnsky LA, Broomall SM, Rosenzweig CN, Skowronski EW, Gibbons HS, Sommer MOA, Dantas G Nature chemical biology 29713061 Nat Chem Biol 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29713061
Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in E. coli Nissle Residing in the Mammalian Gut. Crook N, Ferreiro A, Condiotte Z, Dantas G ACS synthetic biology 32324995 ACS Synth Biol 2020 May 15 https://www.ncbi.nlm.nih.gov/pubmed/32324995
Antibiotics and the developing infant gut microbiota and resistome. Gibson MK, Crofts TS, Dantas G Current opinion in microbiology 26241507 Curr Opin Microbiol 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/26241507
Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA. Gonzales PR, Pesesky MW, Bouley R, Ballard A, Biddy BA, Suckow MA, Wolter WR, Schroeder VA, Burnham CA, Mobashery S, Chang M, Dantas G Nature chemical biology 26368589 Nat Chem Biol 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26368589
Single-cell measurement of red blood cell oxygen affinity. Di Caprio G, Stokes C, Higgins JM, Schonbrun E Proceedings of the National Academy of Sciences of the United States of America 26216973 Proc Natl Acad Sci U S A 2015 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/26216973
Developmental plasticity of red blood cell homeostasis. Golub MS, Hogrefe CE, Malka R, Higgins JM American journal of hematology 24415575 Am J Hematol 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24415575
Data-driven physiologic thresholds for iron deficiency associated with hematologic decline. Foy BH, Li A, McClung JP, Ranganath R, Higgins JM American journal of hematology 31849101 Am J Hematol 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/31849101
Non-Parametric Combined Reference Regions and Prediction of Clinical Risk. Malka R, Brugnara C, Cialic R, Higgins JM Clinical chemistry 32040586 Clin Chem 2020 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/32040586
Hereditary xerocytosis revisited. Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG American journal of hematology 25044010 Am J Hematol 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25044010
Red blood cell population dynamics. Higgins JM Clinics in laboratory medicine 25676371 Clin Lab Med 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25676371
White Blood Cell and Platelet Dynamics Define Human Inflammatory Recovery. Foy BH, Sundt T, Carlson JCT, Aguirre AD, Higgins JM medRxiv : the preprint server for health sciences 34189534 medRxiv 2021 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/34189534
A microfluidic platform to study the effects of vascular architecture and oxygen gradients on sickle blood flow. Lu X, Galarneau MM, Higgins JM, Wood DK Microcirculation (New York, N.Y. : 1994) 28129479 Microcirculation 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28129479
Intracellular water exchange for measuring the dry mass, water mass and changes in chemical composition of living cells. Feijó Delgado F, Cermak N, Hecht VC, Son S, Li Y, Knudsen SM, Olcum S, Higgins JM, Chen J, Grover WH, Manalis SR PloS one 23844039 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23844039
Age-related clonal hematopoiesis associated with adverse outcomes. Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, Kinnunen L, Koistinen HA, Ladenvall C, Getz G, Correa A, Banahan BF, Gabriel S, Kathiresan S, Stringham HM, McCarthy MI, Boehnke M, Tuomilehto J, Haiman C, Groop L, Atzmon G, Wilson JG, Neuberg D, Altshuler D, Ebert BL The New England journal of medicine 25426837 N Engl J Med 2014 Dec 25 https://www.ncbi.nlm.nih.gov/pubmed/25426837
Modulation of red blood cell population dynamics is a fundamental homeostatic response to disease. Patel HH, Patel HR, Higgins JM American journal of hematology 25691355 Am J Hematol 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25691355
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Human acute inflammatory recovery is defined by co-regulatory dynamics of white blood cell and platelet populations. Foy BH, Sundt TM, Carlson JCT, Aguirre AD, Higgins JM Nature communications 35995789 Nat Commun 2022 Aug 22 https://www.ncbi.nlm.nih.gov/pubmed/35995789
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Mechanistic modeling of hemoglobin glycation and red blood cell kinetics enables personalized diabetes monitoring. Malka R, Nathan DM, Higgins JM Science translational medicine 27708063 Sci Transl Med 2016 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/27708063
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Dynamic cell fate plasticity and tissue integration drive functional synovial joint regeneration. Blumenkrantz M, Woron F, Gagarin E, Weinstein E, Kamel MH, Campos L, Geras A, Anderson T, Mo J, Sherwood D, Gwin M, Dumitrascu B, Chahine NO, Smeeton J bioRxiv : the preprint server for biology 39713398 bioRxiv 2024 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/39713398
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Controlled Human Malaria Infection Leads to Long-Lasting Changes in Innate and Innate-like Lymphocyte Populations. Mpina M, Maurice NJ, Yajima M, Slichter CK, Miller HW, Dutta M, McElrath MJ, Stuart KD, De Rosa SC, McNevin JP, Linsley PS, Abdulla S, Tanner M, Hoffman SL, Gottardo R, Daubenberger CA, Prlic M Journal of immunology (Baltimore, Md. : 1950) 28576979 J Immunol 2017 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/28576979
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The human memory T cell compartment changes across tissues of the female reproductive tract. Woodward Davis AS, Vick SC, Pattacini L, Voillet V, Hughes SM, Lentz GM, Kirby AC, Fialkow MF, Gottardo R, Hladik F, Lund JM, Prlic M Mucosal immunology 33953338 Mucosal Immunol 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/33953338
A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire. Oberle SG, Hanna-El-Daher L, Chennupati V, Enouz S, Scherer S, Prlic M, Zehn D Cell reports 27732840 Cell Rep 2016 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/27732840
OMIP-044: 28-color immunophenotyping of the human dendritic cell compartment. Mair F, Prlic M Cytometry. Part A : the journal of the International Society for Analytical Cytology 29356334 Cytometry A 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29356334
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4(+) T Cells in Peripheral Blood of Subjects with Type 1 Diabetes. Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS Journal of immunology (Baltimore, Md. : 1950) 28566371 J Immunol 2017 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/28566371
Anti-proliferative therapy for HIV cure: a compound interest approach. Reeves DB, Duke ER, Hughes SM, Prlic M, Hladik F, Schiffer JT Scientific reports 28638104 Sci Rep 2017 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/28638104
Distinct activation thresholds of human conventional and innate-like memory T cells. Slichter CK, McDavid A, Miller HW, Finak G, Seymour BJ, McNevin JP, Diaz G, Czartoski JL, McElrath MJ, Gottardo R, Prlic M JCI insight 27331143 JCI Insight 2016 Jun 2 https://www.ncbi.nlm.nih.gov/pubmed/27331143
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data. Finak G, McDavid A, Yajima M, Deng J, Gersuk V, Shalek AK, Slichter CK, Miller HW, McElrath MJ, Prlic M, Linsley PS, Gottardo R Genome biology 26653891 Genome Biol 2015 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/26653891

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