Extracellular RNA Communication

Once thought to exist only within cells, RNA is now known to be exported from cells and play a role in newly discovered mechanisms of cell-to-cell communication. The Common Fund’s Extracellular RNA Communication (ERC) program aims to establish fundamental biological principles of extracellular RNA secretion, delivery, and impact on recipient cells; to describe exRNAs in human biofluids and the extent to which non-human exRNAs are present; to test clinical utility of exRNAs; and to provide a data and a resource repository for the community at-large.