Skip to main content

Program Publications

Publications Search by Program

Search Result

The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Author Journal Name PubMedID Journal Abbreviation Publication Date
Cardiovascular disease: The rise of the genetic risk score. Knowles JW, Ashley EA PLoS medicine 29601582 PLoS Med 2018 Mar
Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise. Sanford JA, Nogiec CD, Lindholm ME, Adkins JN, Amar D, Dasari S, Drugan JK, Fernández FM, Radom-Aizik S, Schenk S, Snyder MP, Tracy RP, Vanderboom P, Trappe S, Walsh MJ, Molecular Transducers of Physical Activity Consortium Cell 32589957 Cell 2020 Jun 25
Molecular adaptations in response to exercise training are associated with tissue-specific transcriptomic and epigenomic signatures. Nair VD, Pincas H, Smith GR, Zaslavsky E, Ge Y, Amper MAS, Vasoya M, Chikina M, Sun Y, Raja AN, Mao W, Gay NR, Esser KA, Smith KS, Zhao B, Wiel L, Singh A, Lindholm ME, Amar D, Montgomery S, Snyder MP, Walsh MJ, Sealfon SC, MoTrPAC Study Group Cell genomics 38697122 Cell Genom 2024 Jun 12
Physiological Adaptations to Progressive Endurance Exercise Training in Adult and Aged Rats: Insights from the Molecular Transducers of Physical Activity Consortium (MoTrPAC). Schenk S, Sagendorf TJ, Many GM, Lira AK, de Sousa LGO, Bae D, Cicha M, Kramer KS, Muehlbauer M, Hevener AL, Rector RS, Thyfault JP, Williams JP, Goodyear LJ, Esser KA, Newgard CB, Bodine SC, MoTrPAC Study Group Function (Oxford, England) 38984994 Function (Oxf) 2024 Jul 11
Cardiovascular Precision Medicine in the Genomics Era. Dainis AM, Ashley EA JACC. Basic to translational science 30062216 JACC Basic Transl Sci 2018 Apr
Molecular Transducers of Physical Activity Consortium (MoTrPAC): human studies design and protocol. MoTrPAC Study Group, Jakicic JM, Kohrt WM, Houmard JA, Miller ME, Radom-Aizik S, Rasmussen BB, Ravussin E, Serra M, Stowe CL, Trappe S, Abouassi H, Adkins JN, Alekel DL, Ashley E, Bamman MM, Bergman BC, Bessesen DH, Broskey NT, Buford TW, Burant CF, Chen H, Christle JW, Clish CB, Coen PM, Collier D, Collins KA, Cooper DM, Cortes T, Cutter GR, Dubis G, Fernández FM, Firnhaber J, Forman DE, Gaul DA, Gay N, Gerszten RE, Goodpaster BH, Gritsenko MA, Haddad F, Huffman KM, Ilkayeva O, Jankowski CM, Jin C, Johannsen NM, Johnson J, Kelly L, Kershaw E, Kraus WE, Laughlin M, Lester B, Lindholm ME, Lowe A, Lu CJ, McGowan J, Melanson EL, Montgomery S, Moore SG, Moreau KL, Muehlbauer M, Musi N, Nair VD, Newgard CB, Newman AB, Nicklas B, Nindl BC, Ormond K, Piehowski PD, Qian WJ, Rankinen T, Rejeski WJ, Robbins J, Rogers RJ, Rooney JL, Rushing S, Sanford JA, Schauer IE, Schwartz RS, Sealfon SC, Slentz C, Sloan R, Smith KS, Snyder M, Spahn J, Sparks LM, Stefanovic-Racic M, Tanner CJ, Thalacker-Mercer A, Tracy R, Trappe TA, Volpi E, Walsh MJ, Wheeler MT, Willis L Journal of applied physiology (Bethesda, Md. : 1985) 38634503 J Appl Physiol (1985) 2024 Sep 1
Researcher views on returning results from multi-omics data to research participants: insights from The Molecular Transducers of Physical Activity Consortium (MoTrPAC) Study. Ormond KE, Stanclift C, Reuter CM, Carter JN, Murphy KE, Lindholm ME, Wheeler MT BMC medical ethics 39920727 BMC Med Ethics 2025 Feb 7
Targeted Long-Read RNA Sequencing Demonstrates Transcriptional Diversity Driven by Splice-Site Variation in MYBPC3. Dainis A, Tseng E, Clark TA, Hon T, Wheeler M, Ashley E Circulation. Genomic and precision medicine 31112421 Circ Genom Precis Med 2019 May
Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study. DeBoever C, Tanigawa Y, Lindholm ME, McInnes G, Lavertu A, Ingelsson E, Chang C, Ashley EA, Bustamante CD, Daly MJ, Rivas MA Nature communications 29691392 Nat Commun 2018 Apr 24
Silencing of MYH7 ameliorates disease phenotypes in human iPSC-cardiomyocytes. Dainis A, Zaleta-Rivera K, Ribeiro A, Chang ACH, Shang C, Lan F, Burridge PW, Liu WR, Wu JC, Chang ACY, Pruitt BL, Wheeler M, Ashley E Physiological genomics 32567507 Physiol Genomics 2020 Jul 1
Phenotypic Expression, Natural History, and Risk Stratification of Cardiomyopathy Caused by Filamin C Truncating Variants. Gigli M, Stolfo D, Graw SL, Merlo M, Gregorio C, Nee Chen S, Dal Ferro M, PaldinoMD A, De Angelis G, Brun F, Jirikowic J, Salcedo EE, Turja S, Fatkin D, Johnson R, van Tintelen JP, Te Riele ASJM, Wilde AAM, Lakdawala NK, Picard K, Miani D, Muser D, Maria Severini G, Calkins H, James CA, Murray B, Tichnell C, Parikh VN, Ashley EA, Reuter C, Song J, Judge DP, McKenna WJ, Taylor MRG, Sinagra G, Mestroni L Circulation 34587765 Circulation 2021 Nov 16
The mitochondrial multi-omic response to exercise training across rat tissues. Amar D, Gay NR, Jimenez-Morales D, Jean Beltran PM, Ramaker ME, Raja AN, Zhao B, Sun Y, Marwaha S, Gaul DA, Hershman SG, Ferrasse A, Xia A, Lanza I, Fernández FM, Montgomery SB, Hevener AL, Ashley EA, Walsh MJ, Sparks LM, Burant CF, Rector RS, Thyfault J, Wheeler MT, Goodpaster BH, Coen PM, Schenk S, Bodine SC, Lindholm ME, MoTrPAC Study Group Cell metabolism 38701776 Cell Metab 2024 Jun 4
Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue. Many GM, Sanford JA, Sagendorf TJ, Hou Z, Nigro P, Whytock KL, Amar D, Caputo T, Gay NR, Gaul DA, Hirshman MF, Jimenez-Morales D, Lindholm ME, Muehlbauer MJ, Vamvini M, Bergman BC, Fernández FM, Goodyear LJ, Hevener AL, Ortlund EA, Sparks LM, Xia A, Adkins JN, Bodine SC, Newgard CB, Schenk S, MoTrPAC Study Group Nature metabolism 38693320 Nat Metab 2024 May
Temporal dynamics of the multi-omic response to endurance exercise training. MoTrPAC Study Group, Lead Analysts, MoTrPAC Study Group Nature 38693412 Nature 2024 May
The mitochondrial multi-omic response to exercise training across tissues. Amar D, Gay NR, Jimenez-Morales D, Beltran PMJ, Ramaker ME, Raja AN, Zhao B, Sun Y, Marwaha S, Gaul D, Hershman SG, Xia A, Lanza I, Fernandez FM, Montgomery SB, Hevener AL, Ashley EA, Walsh MJ, Sparks LM, Burant CF, Rector RS, Thyfault J, Wheeler MT, Goodpaster BH, Coen PM, Schenk S, Bodine SC, Lindholm ME, MoTrPAC Study Group bioRxiv : the preprint server for biology 36711881 bioRxiv 2023 Jan 13
Mind the Gap: The Complete Human Genome Unlocks Benefits for Clinical Genomics. Kim DS, Wiel L, Ashley EA Clinical chemistry 36112529 Clin Chem 2023 Jan 4
Protocol for high-throughput DNA methylation profiling in rat tissues using automated reduced representation bisulfite sequencing. Nair VD, Pincas H, Amper MAS, Ge Y, Vasoya M, Raja AN, Walsh MJ, Sealfon SC STAR protocols 38691461 STAR Protoc 2024 Jun 21
Time trajectories in the transcriptomic response to exercise - a meta-analysis. Amar D, Lindholm ME, Norrbom J, Wheeler MT, Rivas MA, Ashley EA Nature communications 34108459 Nat Commun 2021 Jun 9
Endurance Exercise Training Alters Lipidomic Profiles of Plasma and Eight Tissues in Rats: a MoTrPAC study. Ortlund E, Hou Z, Chen CY, Gaul D, Zhang T, Moore S, Liu X, Ivanova A, Maner-Smith K, Newgard C, Bodine S, Savage E, Bennett A, Fernandez F Research square 39606465 Res Sq 2024 Nov 21
Charting the Molecular Terrain of Exercise: Energetics, Exerkines, and the Future of Multiomic Mapping. Katz DH, Lindholm ME, Ashley EA Physiology (Bethesda, Md.) 39136551 Physiology (Bethesda) 2025 Mar 1
Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy. Parikh VN, Ioannidis AG, Jimenez-Morales D, Gorzynski JE, De Jong HN, Liu X, Roque J, Cepeda-Espinoza VP, Osoegawa K, Hughes C, Sutton SC, Youlton N, Joshi R, Amar D, Tanigawa Y, Russo D, Wong J, Lauzon JT, Edelson J, Mas Montserrat D, Kwon Y, Rubinacci S, Delaneau O, Cappello L, Kim J, Shoura MJ, Raja AN, Watson N, Hammond N, Spiteri E, Mallempati KC, Montero-Martín G, Christle J, Kim J, Kirillova A, Seo K, Huang Y, Zhao C, Moreno-Grau S, Hershman SG, Dalton KP, Zhen J, Kamm J, Bhatt KD, Isakova A, Morri M, Ranganath T, Blish CA, Rogers AJ, Nadeau K, Yang S, Blomkalns A, O'Hara R, Neff NF, DeBoever C, Szalma S, Wheeler MT, Gates CM, Farh K, Schroth GP, Febbo P, deSouza F, Cornejo OE, Fernandez-Vina M, Kistler A, Palacios JA, Pinsky BA, Bustamante CD, Rivas MA, Ashley EA Nature communications 36042219 Nat Commun 2022 Aug 30
Multi-omic identification of key transcriptional regulatory programs during endurance exercise training. Smith GR, Zhao B, Lindholm ME, Raja A, Viggars M, Pincas H, Gay NR, Sun Y, Ge Y, Nair VD, Sanford JA, Amper MAS, Vasoya M, Smith KS, Montgomery S, Zaslavsky E, Bodine SC, Esser KA, Walsh MJ, Snyder MP, MoTrPAC Study Group bioRxiv : the preprint server for biology 36711841 bioRxiv 2023 Oct 23
The impact of exercise on gene regulation in association with complex trait genetics. Vetr NG, Gay NR, MoTrPAC Study Group, Montgomery SB Nature communications 38693125 Nat Commun 2024 May 1
Alterations of the skeletal muscle nuclear proteome after acute exercise reveals a post-transcriptional influence. Martin RA, Viggars MR, Sanford JA, Taylor ZW, Hansen JR, Clair GC, Adkins JN, Douglas CM, Esser KA bioRxiv : the preprint server for biology 39149399 bioRxiv 2024 Aug 9
Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation. Gaffrey MJ, Day NJ, Li X, Qian WJ Journal of visualized experiments : JoVE 34223836 J Vis Exp 2021 Jun 21
Fatiguing contractions increase protein S-glutathionylation occupancy in mouse skeletal muscle. Kramer PA, Duan J, Gaffrey MJ, Shukla AK, Wang L, Bammler TK, Qian WJ, Marcinek DJ Redox biology 29857311 Redox Biol 2018 Jul
Rapidly Assessing the Quality of Targeted Proteomics Experiments through Monitoring Stable-Isotope Labeled Standards. Gibbons BC, Fillmore TL, Gao Y, Moore RJ, Liu T, Nakayasu ES, Metz TO, Payne SH Journal of proteome research 30525668 J Proteome Res 2019 Feb 1
Characterization of cellular oxidative stress response by stoichiometric redox proteomics. Zhang T, Gaffrey MJ, Li X, Qian WJ American journal of physiology. Cell physiology 33264075 Am J Physiol Cell Physiol 2021 Feb 1
Assessment of TMT Labeling Efficiency in Large-Scale Quantitative Proteomics: The Critical Effect of Sample pH. Hutchinson-Bunch C, Sanford JA, Hansen JR, Gritsenko MA, Rodland KD, Piehowski PD, Qian WJ, Adkins JN ACS omega 34056417 ACS Omega 2021 May 18
A deep redox proteome profiling workflow and its application to skeletal muscle of a Duchenne Muscular Dystrophy model. Day NJ, Zhang T, Gaffrey MJ, Zhao R, Fillmore TL, Moore RJ, Rodney GG, Qian WJ Free radical biology & medicine 36306991 Free Radic Biol Med 2022 Nov 20
Leveraging Mobile Technology for Public Health Promotion: A Multidisciplinary Perspective. Hicks JL, Boswell MA, Althoff T, Crum AJ, Ku JP, Landay JA, Moya PML, Murnane EL, Snyder MP, King AC, Delp SL Annual review of public health 36542772 Annu Rev Public Health 2023 Apr 3
Exerkines in health, resilience and disease. Chow LS, Gerszten RE, Taylor JM, Pedersen BK, van Praag H, Trappe S, Febbraio MA, Galis ZS, Gao Y, Haus JM, Lanza IR, Lavie CJ, Lee CH, Lucia A, Moro C, Pandey A, Robbins JM, Stanford KI, Thackray AE, Villeda S, Watt MJ, Xia A, Zierath JR, Goodpaster BH, Snyder MP Nature reviews. Endocrinology 35304603 Nat Rev Endocrinol 2022 May
Dynamic DNA methylation: In the right place at the right time. Luo C, Hajkova P, Ecker JR Science (New York, N.Y.) 30262495 Science 2018 Sep 28
Nonsense-mediated decay is highly stable across individuals and tissues. Teran NA, Nachun DC, Eulalio T, Ferraro NM, Smail C, Rivas MA, Montgomery SB American journal of human genetics 34216550 Am J Hum Genet 2021 Aug 5
Untargeted Metabolomics Differentiates l-Carnitine Treated Septic Shock 1-Year Survivors and Nonsurvivors. Evans CR, Karnovsky A, Puskarich MA, Michailidis G, Jones AE, Stringer KA Journal of proteome research 30895797 J Proteome Res 2019 May 3
Higher mitochondrial oxidative capacity is the primary molecular differentiator in muscle of rats with high and low intrinsic cardiorespiratory fitness. Fleischman JY, Van den Bergh F, Collins NL, Bowers M, Beard DA, Burant CF Molecular metabolism 37625738 Mol Metab 2023 Oct
International Ring Trial of a High Resolution Targeted Metabolomics and Lipidomics Platform for Serum and Plasma Analysis. Thompson JW, Adams KJ, Adamski J, Asad Y, Borts D, Bowden JA, Byram G, Dang V, Dunn WB, Fernandez F, Fiehn O, Gaul DA, Hühmer AF, Kalli A, Koal T, Koeniger S, Mandal R, Meier F, Naser FJ, O'Neil D, Pal A, Patti GJ, Pham-Tuan H, Prehn C, Raynaud FI, Shen T, Southam AD, St John-Williams L, Sulek K, Vasilopoulou CG, Viant M, Winder CL, Wishart D, Zhang L, Zheng J, Moseley MA Analytical chemistry 31638379 Anal Chem 2019 Nov 19
Mass Spectrometry-Based Non-targeted Metabolic Profiling for Disease Detection: Recent Developments. Zang X, Monge ME, Fernández FM Trends in analytical chemistry : TRAC 32831436 Trends Analyt Chem 2019 Sep
Ambient mass spectrometry in metabolomics. Clendinen CS, Monge ME, Fernández FM The Analyst 28792022 Analyst 2017 Aug 21
Triboelectric Nanogenerators: Low-Cost Power Supplies for Improved Electrospray Ionization. Vallejo DD, Corstvet JL, Fernández FM International journal of mass spectrometry 38053979 Int J Mass Spectrom 2024 Jan
The COVID-19 MS Coalition-accelerating diagnostics, prognostics, and treatment. Struwe W, Emmott E, Bailey M, Sharon M, Sinz A, Corrales FJ, Thalassinos K, Braybrook J, Mills C, Barran P, COVID-19 MS Coalition Lancet (London, England) 32473097 Lancet 2020 Jun 6
Metabolomics and adductomics of newborn bloodspots to retrospectively assess the early-life exposome. Petrick LM, Uppal K, Funk WE Current opinion in pediatrics 31913157 Curr Opin Pediatr 2020 Apr
Challenges in Identifying the Dark Molecules of Life. Monge ME, Dodds JN, Baker ES, Edison AS, Fernández FM Annual review of analytical chemistry (Palo Alto, Calif.) 30883183 Annu Rev Anal Chem (Palo Alto Calif) 2019 Jun 12
Triboelectric Nanogenerator Ion Mobility-Mass Spectrometry for In-Depth Lipid Annotation. Bouza M, Li Y, Wang AC, Wang ZL, Fernández FM Analytical chemistry 33720699 Anal Chem 2021 Apr 6
The HERITAGE Family Study: A Review of the Effects of Exercise Training on Cardiometabolic Health, with Insights into Molecular Transducers. Sarzynski MA, Rice TK, Després JP, Pérusse L, Tremblay A, Stanforth PR, Tchernof A, Barber JL, Falciani F, Clish C, Robbins JM, Ghosh S, Gerszten RE, Leon AS, Skinner JS, Rao DC, Bouchard C Medicine and science in sports and exercise 35611651 Med Sci Sports Exerc 2022 May 1
Metabolomics and Proteomics in Type 2 Diabetes. Chen ZZ, Gerszten RE Circulation research 32437301 Circ Res 2020 May 22
Rapid and deep-scale ubiquitylation profiling for biology and translational research. Udeshi ND, Mani DC, Satpathy S, Fereshetian S, Gasser JA, Svinkina T, Olive ME, Ebert BL, Mertins P, Carr SA Nature communications 31953384 Nat Commun 2020 Jan 17
Exercise, exerkines, and cardiometabolic health: from individual players to a team sport. Robbins JM, Gerszten RE The Journal of clinical investigation 37395284 J Clin Invest 2023 Jul 3
Exercise, exerkines, and cardiometabolic health: from individual players to a team sport. Robbins JM, Gerszten RE The Journal of clinical investigation 37259917 J Clin Invest 2023 Jun 1
CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1. Belizaire R, Koochaki SHJ, Udeshi ND, Vedder A, Sun L, Svinkina T, Hartigan C, McConkey M, Kovalcik V, Bizuayehu A, Stanclift C, Schenone M, Carr SA, Padron E, Ebert BL Blood 33512474 Blood 2021 Apr 22
Plasma Metabolite Profiles in Response to Chronic Exercise. Brennan AM, Benson M, Morningstar J, Herzig M, Robbins J, Gerszten RE, Ross R Medicine and science in sports and exercise 29509640 Med Sci Sports Exerc 2018 Jul
Emerging Affinity Reagents for High Throughput Proteomics: Trust, but Verify. Benson MD, Ngo D, Ganz P, Gerszten RE Circulation 31710523 Circulation 2019 Nov 12
Human plasma proteomic profiles indicative of cardiorespiratory fitness. Robbins JM, Peterson B, Schranner D, Tahir UA, Rienmüller T, Deng S, Keyes MJ, Katz DH, Beltran PMJ, Barber JL, Baumgartner C, Carr SA, Ghosh S, Shen C, Jennings LL, Ross R, Sarzynski MA, Bouchard C, Gerszten RE Nature metabolism 34045743 Nat Metab 2021 Jun
Cardiovascular Risk Beyond Low-Density Lipoprotein Cholesterol. Mayr M, Gerszten R, Kiechl S Journal of the American College of Cardiology 29420959 J Am Coll Cardiol 2018 Feb 13
Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes. O'Sullivan JF, Morningstar JE, Yang Q, Zheng B, Gao Y, Jeanfavre S, Scott J, Fernandez C, Zheng H, O'Connor S, Cohen P, Vasan RS, Long MT, Wilson JG, Melander O, Wang TJ, Fox C, Peterson RT, Clish CB, Corey KE, Gerszten RE The Journal of clinical investigation 29083323 J Clin Invest 2017 Dec 1
Association of Dimethylguanidino Valeric Acid With Partial Resistance to Metabolic Health Benefits of Regular Exercise. Robbins JM, Herzig M, Morningstar J, Sarzynski MA, Cruz DE, Wang TJ, Gao Y, Wilson JG, Bouchard C, Rankinen T, Gerszten RE JAMA cardiology 31166569 JAMA Cardiol 2019 Jul 1
Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods. Katz DH, Robbins JM, Deng S, Tahir UA, Bick AG, Pampana A, Yu Z, Ngo D, Benson MD, Chen ZZ, Cruz DE, Shen D, Gao Y, Bouchard C, Sarzynski MA, Correa A, Natarajan P, Wilson JG, Gerszten RE Science advances 35984888 Sci Adv 2022 Aug 19
Author Correction: Human plasma proteomic profiles indicative of cardiorespiratory fitness. Robbins JM, Peterson B, Schranner D, Tahir UA, Rienmüller T, Deng S, Keyes MJ, Katz DH, Beltran PMJ, Barber JL, Baumgartner C, Carr SA, Ghosh S, Shen C, Jennings LL, Ross R, Sarzynski MA, Bouchard C, Gerszten RE Nature metabolism 34446928 Nat Metab 2021 Sep
Protein-metabolite association studies identify novel proteomic determinants of metabolite levels in human plasma. Benson MD, Eisman AS, Tahir UA, Katz DH, Deng S, Ngo D, Robbins JM, Hofmann A, Shi X, Zheng S, Keyes M, Yu Z, Gao Y, Farrell L, Shen D, Chen ZZ, Cruz DE, Sims M, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Jain D, Yang Q, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Sarkar IN, Natarajan P, Gerszten RE Cell metabolism 37582364 Cell Metab 2023 Sep 5
TMT Labeling for the Masses: A Robust and Cost-efficient, In-solution Labeling Approach. Zecha J, Satpathy S, Kanashova T, Avanessian SC, Kane MH, Clauser KR, Mertins P, Carr SA, Kuster B Molecular & cellular proteomics : MCP 30967486 Mol Cell Proteomics 2019 Jul
Succinate links atrial dysfunction and cardioembolic stroke. Nelson SE, Ament Z, Wolcott Z, Gerszten RE, Kimberly WT Neurology 30674589 Neurology 2019 Feb 19
Omics-driven investigation of the biology underlying intrinsic submaximal working capacity and its trainability. Hota M, Barber JL, Ruiz-Ramie JJ, Schwartz CS, Lam DTUH, Rao P, Mi MY, Katz DH, Robbins JM, Clish CB, Gerszten RE, Sarzynski MA, Ghosh S, Bouchard C Physiological genomics 37661925 Physiol Genomics 2023 Nov 1
Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk. Castel SE, Cervera A, Mohammadi P, Aguet F, Reverter F, Wolman A, Guigo R, Iossifov I, Vasileva A, Lappalainen T Nature genetics 30127527 Nat Genet 2018 Sep
A vast resource of allelic expression data spanning human tissues. Castel SE, Aguet F, Mohammadi P, GTEx Consortium, Ardlie KG, Lappalainen T Genome biology 32912332 Genome Biol 2020 Sep 11
Non-negative Independent Factor Analysis disentangles discrete and continuous sources of variation in scRNA-seq data. Mao W, Pouyan MB, Kostka D, Chikina M Bioinformatics (Oxford, England) 35561207 Bioinformatics 2022 May 13
Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity. Whytock KL, Pino MF, Sun Y, Yu G, De Carvalho FG, Yeo RX, Vega RB, Parmar G, Divoux A, Kapoor N, Yi F, Cornnell H, Patten DA, Harper ME, Gardell SJ, Smith SR, Walsh MJ, Sparks LM American journal of physiology. Endocrinology and metabolism 37584609 Am J Physiol Endocrinol Metab 2023 Oct 1
Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells. Sun Y, Asano K, Sedes L, Cantalupo A, Hansen J, Iyengar R, Walsh MJ, Ramirez F JCI insight 37022786 JCI Insight 2023 May 22
An intrinsically interpretable neural network architecture for sequence-to-function learning. Balcı AT, Ebeid MM, Benos PV, Kostka D, Chikina M Bioinformatics (Oxford, England) 37387140 Bioinformatics 2023 Jun 30
Sedentary and Trained Older Men Have Distinct Circulating Exosomal microRNA Profiles at Baseline and in Response to Acute Exercise. Nair VD, Ge Y, Li S, Pincas H, Jain N, Seenarine N, Amper MAS, Goodpaster BH, Walsh MJ, Coen PM, Sealfon SC Frontiers in physiology 32587527 Front Physiol 2020
Single-cell transcriptional profiles in human skeletal muscle. Rubenstein AB, Smith GR, Raue U, Begue G, Minchev K, Ruf-Zamojski F, Nair VD, Wang X, Zhou L, Zaslavsky E, Trappe TA, Trappe S, Sealfon SC Scientific reports 31937892 Sci Rep 2020 Jan 14
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations. Kim-Hellmuth S, Bechheim M, Pütz B, Mohammadi P, Nédélec Y, Giangreco N, Becker J, Kaiser V, Fricker N, Beier E, Boor P, Castel SE, Nöthen MM, Barreiro LB, Pickrell JK, Müller-Myhsok B, Lappalainen T, Schumacher J, Hornung V Nature communications 28814792 Nat Commun 2017 Aug 16
DataRemix: a universal data transformation for optimal inference from gene expression datasets. Mao W, Rahimikollu J, Hausler R, Chikina M Bioinformatics (Oxford, England) 32821903 Bioinformatics 2021 May 17
Pathway-level information extractor (PLIER) for gene expression data. Mao W, Zaslavsky E, Hartmann BM, Sealfon SC, Chikina M Nature methods 31249421 Nat Methods 2019 Jul
Heterogeneous origins and functions of mouse skeletal muscle-resident macrophages. Wang X, Sathe AA, Smith GR, Ruf-Zamojski F, Nair V, Lavine KJ, Xing C, Sealfon SC, Zhou L Proceedings of the National Academy of Sciences of the United States of America 32796104 Proc Natl Acad Sci U S A 2020 Aug 25
A micromachined force sensing apparatus and method for human engineered cardiac tissue and induced pluripotent stem cell characterization. Turnbull IC, Zhu W, Stillitano F, Chien CC, Gaitas A Sensors and actuators. A, Physical 34305317 Sens Actuators A Phys 2021 Nov 1
Transcriptome variation in human tissues revealed by long-read sequencing. Glinos DA, Garborcauskas G, Hoffman P, Ehsan N, Jiang L, Gokden A, Dai X, Aguet F, Brown KL, Garimella K, Bowers T, Costello M, Ardlie K, Jian R, Tucker NR, Ellinor PT, Harrington ED, Tang H, Snyder M, Juul S, Mohammadi P, MacArthur DG, Lappalainen T, Cummings BB Nature 35922509 Nature 2022 Aug
AFM Microfluidic Cantilevers as Weight Sensors for Live Single Cell Mass Measurements. Chien CC, Jiang J, Gong B, Li T, Gaitas A Measurement science & technology 35832465 Meas Sci Technol 2022 Sep
Skeletal muscle transcriptional networks linked to type I myofiber grouping in Parkinson's disease. Lavin KM, Sealfon SC, McDonald MN, Roberts BM, Wilk K, Nair VD, Ge Y, Lakshman Kumar P, Windham ST, Bamman MM Journal of applied physiology (Bethesda, Md. : 1985) 31829804 J Appl Physiol (1985) 2020 Feb 1
Rehabilitative Impact of Exercise Training on Human Skeletal Muscle Transcriptional Programs in Parkinson's Disease. Lavin KM, Ge Y, Sealfon SC, Nair VD, Wilk K, McAdam JS, Windham ST, Kumar PL, McDonald MN, Bamman MM Frontiers in physiology 32625117 Front Physiol 2020
A size-exclusion-based approach for purifying extracellular vesicles from human plasma. Vanderboom PM, Dasari S, Ruegsegger GN, Pataky MW, Lucien F, Heppelmann CJ, Lanza IR, Nair KS Cell reports methods 34355211 Cell Rep Methods 2021 Jul 26
Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes. Ruegsegger GN, Manjunatha S, Summer P, Gopala S, Zabeilski P, Dasari S, Vanderboom PM, Lanza IR, Klaus KA, Nair KS FASEB journal : official publication of the Federation of American Societies for Experimental Biology 30676773 FASEB J 2019 Mar
Rapid report on using data to make standardized decisions about enrollment during the COVID-19 pandemic: perspectives from the MoTrPAC study. George SM, Chen H, Miller ME, Rejeski WJ, Stowe CL, Webb C, Kraus WE, Musi N, Jakicic JM Annals of epidemiology 33957248 Ann Epidemiol 2021 Oct
Isolation of nuclei from frozen human subcutaneous adipose tissue for full-length single-nuclei transcriptional profiling. Whytock KL, Divoux A, Sun Y, Hopf M, Yeo RX, Pino MF, Yu G, Smith SR, Walsh MJ, Sparks LM STAR protocols 36853719 STAR Protoc 2023 Mar 17
Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue. Many GM, Sanford JA, Sagendorf TJ, Hou Z, Nigro P, Whytock K, Amar D, Caputo T, Gay NR, Gaul DA, Hirshman M, Jimenez-Morales D, Lindholm ME, Muehlbauer MJ, Vamvini M, Bergman B, Fern Ndez FM, Goodyear LJ, Ortlund EA, Sparks LM, Xia A, Adkins JN, Bodine SC, Newgard CB, Schenk S, MoTrPAC Study Group bioRxiv : the preprint server for biology 36778330 bioRxiv 2023 Feb 4
Daily energy expenditure through the human life course. Pontzer H, Yamada Y, Sagayama H, Ainslie PN, Andersen LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, Blanc S, Bonomi AG, Bouten CVC, Bovet P, Buchowski MS, Butte NF, Camps SG, Close GL, Cooper JA, Cooper R, Das SK, Dugas LR, Ekelund U, Entringer S, Forrester T, Fudge BW, Goris AH, Gurven M, Hambly C, El Hamdouchi A, Hoos MB, Hu S, Joonas N, Joosen AM, Katzmarzyk P, Kempen KP, Kimura M, Kraus WE, Kushner RF, Lambert EV, Leonard WR, Lessan N, Martin C, Medin AC, Meijer EP, Morehen JC, Morton JP, Neuhouser ML, Nicklas TA, Ojiambo RM, Pietiläinen KH, Pitsiladis YP, Plange-Rhule J, Plasqui G, Prentice RL, Rabinovich RA, Racette SB, Raichlen DA, Ravussin E, Reynolds RM, Roberts SB, Schuit AJ, Sjödin AM, Stice E, Urlacher SS, Valenti G, Van Etten LM, Van Mil EA, Wells JCK, Wilson G, Wood BM, Yanovski J, Yoshida T, Zhang X, Murphy-Alford AJ, Loechl C, Luke AH, Rood J, Schoeller DA, Westerterp KR, Wong WW, Speakman JR, IAEA DLW Database Consortium Science (New York, N.Y.) 34385400 Science 2021 Aug 13
Energy compensation and adiposity in humans. Careau V, Halsey LG, Pontzer H, Ainslie PN, Andersen LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, Blanc S, Bonomi AG, Bouten CVC, Buchowski MS, Butte NF, Camps SGJA, Close GL, Cooper JA, Das SK, Cooper R, Dugas LR, Eaton SD, Ekelund U, Entringer S, Forrester T, Fudge BW, Goris AH, Gurven M, Hambly C, El Hamdouchi A, Hoos MB, Hu S, Joonas N, Joosen AM, Katzmarzyk P, Kempen KP, Kimura M, Kraus WE, Kushner RF, Lambert EV, Leonard WR, Lessan N, Martin CK, Medin AC, Meijer EP, Morehen JC, Morton JP, Neuhouser ML, Nicklas TA, Ojiambo RM, Pietiläinen KH, Pitsiladis YP, Plange-Rhule J, Plasqui G, Prentice RL, Rabinovich RA, Racette SB, Raichlen DA, Ravussin E, Reilly JJ, Reynolds RM, Roberts SB, Schuit AJ, Sjödin AM, Stice E, Urlacher SS, Valenti G, Van Etten LM, Van Mil EA, Wells JCK, Wilson G, Wood BM, Yanovski J, Yoshida T, Zhang X, Murphy-Alford AJ, Loechl CU, Luke AH, Rood J, Sagayama H, Schoeller DA, Wong WW, Yamada Y, Speakman JR, IAEA DLW database group Current biology : CB 34453886 Curr Biol 2021 Oct 25
Supramax exercise testing in cystic fibrosis: not ready for prime time. Cooper DM Journal of applied physiology (Bethesda, Md. : 1985) 30694710 J Appl Physiol (1985) 2019 Jan 1
Decline of Psychological Health Following the Designation of COVID-19 as a Pandemic: Descriptive Study. Patel DI, Gamez Y, Shah L, Patel J Journal of medical Internet research 33793408 J Med Internet Res 2021 Apr 22
Impact of Geroscience on Therapeutic Strategies for Older Adults With Cardiovascular Disease: JACC Scientific Statement. Forman DE, Kuchel GA, Newman JC, Kirkland JL, Volpi E, Taffet GE, Barzilai N, Pandey A, Kitzman DW, Libby P, Ferrucci L Journal of the American College of Cardiology 37389519 J Am Coll Cardiol 2023 Aug 15
Exercise preserves muscle mass and force in a prostate cancer mouse model. Patel DI, Abuchowski K, Sheikh B, Rivas P, Musi N, Kumar AP European journal of translational myology 31908747 Eur J Transl Myol 2019 Oct 29
Nexrutine and exercise similarly prevent high grade prostate tumors in transgenic mouse model. Patel DI, Abuchowski K, Bedolla R, Rivas P, Musi N, Reddick R, Kumar AP PloS one 31856170 PLoS One 2019
Nursing Research, CER, PICO and PCORI. Patel DI Journal of community & public health nursing 29676399 J Community Public Health Nurs 2018
Mechanisms of exercise as a preventative measure to muscle wasting. Graham ZA, Lavin KM, O'Bryan SM, Thalacker-Mercer AE, Buford TW, Ford KM, Broderick TJ, Bamman MM American journal of physiology. Cell physiology 33950699 Am J Physiol Cell Physiol 2021 Jul 1
A Role for Exercise to Counter Skeletal Muscle Clock Disruption. Erickson ML, Esser KA, Kraus WE, Buford TW, Redman LM Exercise and sport sciences reviews 33044328 Exerc Sport Sci Rev 2021 Jan
Influence of low-dose aspirin, resistance exercise, and sex on human skeletal muscle PGE(2) /COX pathway activity. Naruse M, Fountain WA, Claiborne A, Chambers TL, Jones AM, Stroh AM, Montenegro CF, Lynch CE, Minchev K, Trappe S, Trappe TA Physiological reports 33661544 Physiol Rep 2021 Mar
A single nuclei atlas of aging human abdominal subcutaneous white adipose tissue. Sparks L, Whytock K, Divoux A, Sun Y, Pino M, Yu G, Smith S, Walsh M Research square 37503028 Res Sq 2023 Jul 13
Mechanistic Insights Into the Exercise-Induced Changes in Muscle Lipids and Insulin Sensitivity-Expanding on the "Athlete's Paradox": Revisiting a 2011 Diabetes Classic by Amati et al. Horowitz JF, Goodpaster BH Diabetes 39836884 Diabetes 2025 Feb 1
Human adipose and skeletal muscle tissue DNA, RNA, and protein content. Stroh AM, Lynch CE, Lester BE, Minchev K, Chambers TL, Montenegro CF, Chavez Martinez C, Fountain WA, Trappe TA, Trappe SW Journal of applied physiology (Bethesda, Md. : 1985) 34435508 J Appl Physiol (1985) 2021 Oct 1
Muscle transcriptional networks linked to resistance exercise training hypertrophic response heterogeneity. Lavin KM, Bell MB, McAdam JS, Peck BD, Walton RG, Windham ST, Tuggle SC, Long DE, Kern PA, Peterson CA, Bamman MM Physiological genomics 33870722 Physiol Genomics 2021 May 1
Multitissue responses to exercise: a MoTrPAC feasibility study. Chambers TL, Stroh AM, Chavez C, Brandt AR, Claiborne A, Fountain WA, Gries KJ, Jones AM, Kuszmaul DJ, Lee GA, Lester BE, Lynch CE, Minchev K, Montenegro CF, Naruse M, Raue U, Trappe TA, Trappe S Journal of applied physiology (Bethesda, Md. : 1985) 37318985 J Appl Physiol (1985) 2023 Aug 1
Single cell full-length transcriptome of human subcutaneous adipose tissue reveals unique and heterogeneous cell populations. Whytock KL, Sun Y, Divoux A, Yu G, Smith SR, Walsh MJ, Sparks LM iScience 35992069 iScience 2022 Aug 19
An optimized pipeline for high-throughput bulk RNA-Seq deconvolution illustrates the impact of obesity and weight loss on cell composition of human adipose tissue. Ahn C, Divoux A, Zhou M, Seldin MM, Sparks LM, Whytock KL bioRxiv : the preprint server for biology 39386599 bioRxiv 2024 Sep 25
Pyruvate Kinase M2 Supports Muscle Progenitor Cell Proliferation but Is Dispensable for Skeletal Muscle Regeneration after Injury. Blum JE, Gheller BJ, Benvie A, Field MS, Panizza E, Vacanti NM, Berry D, Thalacker-Mercer A The Journal of nutrition 34383048 J Nutr 2021 Nov 2
miR-486 is essential for muscle function and suppresses a dystrophic transcriptome. Samani A, Hightower RM, Reid AL, English KG, Lopez MA, Doyle JS, Conklin MJ, Schneider DA, Bamman MM, Widrick JJ, Crossman DK, Xie M, Jee D, Lai EC, Alexander MS Life science alliance 35512829 Life Sci Alliance 2022 Sep
State of Knowledge on Molecular Adaptations to Exercise in Humans: Historical Perspectives and Future Directions. Lavin KM, Coen PM, Baptista LC, Bell MB, Drummer D, Harper SA, Lixandrão ME, McAdam JS, O'Bryan SM, Ramos S, Roberts LM, Vega RB, Goodpaster BH, Bamman MM, Buford TW Comprehensive Physiology 35578962 Compr Physiol 2022 Mar 9
When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging. Mihaylova MM, Chaix A, Delibegovic M, Ramsey JJ, Bass J, Melkani G, Singh R, Chen Z, Ja WW, Shirasu-Hiza M, Latimer MN, Mattison JA, Thalacker-Mercer AE, Dixit VD, Panda S, Lamming DW Cell metabolism 37392742 Cell Metab 2023 Jul 11
Cardiac Rehabilitation in Frail Older Adults With Cardiovascular Disease: A NEW DIAGNOSTIC AND TREATMENT PARADIGM. Flint KM, Stevens-Lapsley J, Forman DE Journal of cardiopulmonary rehabilitation and prevention 31939755 J Cardiopulm Rehabil Prev 2020 Mar
Research Priorities in the Secondary Prevention of Atrial Fibrillation: A National Heart, Lung, and Blood Institute Virtual Workshop Report. Benjamin EJ, Al-Khatib SM, Desvigne-Nickens P, Alonso A, Djoussé L, Forman DE, Gillis AM, Hendriks JML, Hills MT, Kirchhof P, Link MS, Marcus GM, Mehra R, Murray KT, Parkash R, Piña IL, Redline S, Rienstra M, Sanders P, Somers VK, Van Wagoner DR, Wang PJ, Cooper LS, Go AS Journal of the American Heart Association 34351783 J Am Heart Assoc 2021 Aug 17
Gerotechnology for Older Adults With Cardiovascular Diseases: JACC State-of-the-Art Review. Krishnaswami A, Beavers C, Dorsch MP, Dodson JA, Masterson Creber R, Kitsiou S, Goyal P, Maurer MS, Wenger NK, Croy DS, Alexander KP, Batsis JA, Turakhia MP, Forman DE, Bernacki GM, Kirkpatrick JN, Orr NM, Peterson ED, Rich MW, Freeman AM, Bhavnani SP, Innovations, Cardiovascular Team and the Geriatric Cardiology Councils, American College of Cardiology Journal of the American College of Cardiology 33243384 J Am Coll Cardiol 2020 Dec 1
Cardiovascular Biomarkers and Imaging in Older Adults: JACC Council Perspectives. Forman DE, de Lemos JA, Shaw LJ, Reuben DB, Lyubarova R, Peterson ED, Spertus JA, Zieman S, Salive ME, Rich MW, Geriatric Cardiology Section Leadership Council Journal of the American College of Cardiology 32972536 J Am Coll Cardiol 2020 Sep 29
Cardiac Rehabilitation for Patients With Heart Failure: JACC Expert Panel. Bozkurt B, Fonarow GC, Goldberg LR, Guglin M, Josephson RA, Forman DE, Lin G, Lindenfeld J, O'Connor C, Panjrath G, Piña IL, Shah T, Sinha SS, Wolfel E, ACC’s Heart Failure and Transplant Section and Leadership Council Journal of the American College of Cardiology 33736829 J Am Coll Cardiol 2021 Mar 23
Impact of Age on Comorbidities and Outcomes in Heart Failure With Reduced Ejection Fraction. Regan JA, Kitzman DW, Leifer ES, Kraus WE, Fleg JL, Forman DE, Whellan DJ, Wojdyla D, Parikh K, O'Connor CM, Mentz RJ JACC. Heart failure 31779928 JACC Heart Fail 2019 Dec
Impaired Exercise Tolerance in Heart Failure: Role of Skeletal Muscle Morphology and Function. Tucker WJ, Haykowsky MJ, Seo Y, Stehling E, Forman DE Current heart failure reports 30178183 Curr Heart Fail Rep 2018 Dec
Never Too Old for Cardiac Rehabilitation. O'Neill D, Forman DE Clinics in geriatric medicine 31543175 Clin Geriatr Med 2019 Nov
The importance of physical function as a clinical outcome: Assessment and enhancement. O'Neill D, Forman DE Clinical cardiology 31825137 Clin Cardiol 2020 Feb
Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop. Espinoza SE, Khosla S, Baur JA, de Cabo R, Musi N The journals of gerontology. Series A, Biological sciences and medical sciences 37325957 J Gerontol A Biol Sci Med Sci 2023 Jun 16
The role of androgens in microvascular endothelial dysfunction in polycystic ovary syndrome: does size matter? Moreau KL, DuBose LE The Journal of physiology 31025703 J Physiol 2019 Jun
Body composition and cardiometabolic health across the menopause transition. Marlatt KL, Pitynski-Miller DR, Gavin KM, Moreau KL, Melanson EL, Santoro N, Kohrt WM Obesity (Silver Spring, Md.) 34932890 Obesity (Silver Spring) 2022 Jan
Molecular Mechanisms of Exercise and Healthspan. Guan Y, Yan Z Cells 35269492 Cells 2022 Mar 3
AMPK and the Adaptation to Exercise. Spaulding HR, Yan Z Annual review of physiology 35143330 Annu Rev Physiol 2022 Feb 10
Leveraging inter-individual transcriptional correlation structure to infer discrete signaling mechanisms across metabolic tissues. Zhou M, Tamburini I, Van C, Molendijk J, Nguyen CM, Chang IY, Johnson C, Velez LM, Cheon Y, Yeo R, Bae H, Le J, Larson N, Pulido R, Nascimento-Filho CHV, Jang C, Marazzi I, Justice J, Pannunzio N, Hevener AL, Sparks L, Kershaw EE, Nicholas D, Parker BL, Masri S, Seldin MM eLife 38224289 Elife 2024 Jan 15
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. Wang Z, Emmerich A, Pillon NJ, Moore T, Hemerich D, Cornelis MC, Mazzaferro E, Broos S, Ahluwalia TS, Bartz TM, Bentley AR, Bielak LF, Chong M, Chu AY, Berry D, Dorajoo R, Dueker ND, Kasbohm E, Feenstra B, Feitosa MF, Gieger C, Graff M, Hall LM, Haller T, Hartwig FP, Hillis DA, Huikari V, Heard-Costa N, Holzapfel C, Jackson AU, Johansson Å, Jørgensen AM, Kaakinen MA, Karlsson R, Kerr KF, Kim B, Koolhaas CM, Kutalik Z, Lagou V, Lind PA, Lorentzon M, Lyytikäinen LP, Mangino M, Metzendorf C, Monroe KR, Pacolet A, Pérusse L, Pool R, Richmond RC, Rivera NV, Robiou-du-Pont S, Schraut KE, Schulz CA, Stringham HM, Tanaka T, Teumer A, Turman C, van der Most PJ, Vanmunster M, van Rooij FJA, van Vliet-Ostaptchouk JV, Zhang X, Zhao JH, Zhao W, Balkhiyarova Z, Balslev-Harder MN, Baumeister SE, Beilby J, Blangero J, Boomsma DI, Brage S, Braund PS, Brody JA, Bruinenberg M, Ekelund U, Liu CT, Cole JW, Collins FS, Cupples LA, Esko T, Enroth S, Faul JD, Fernandez-Rhodes L, Fohner AE, Franco OH, Galesloot TE, Gordon SD, Grarup N, Hartman CA, Heiss G, Hui J, Illig T, Jago R, James A, Joshi PK, Jung T, Kähönen M, Kilpeläinen TO, Koh WP, Kolcic I, Kraft PP, Kuusisto J, Launer LJ, Li A, Linneberg A, Luan J, Vidal PM, Medland SE, Milaneschi Y, Moscati A, Musk B, Nelson CP, Nolte IM, Pedersen NL, Peters A, Peyser PA, Power C, Raitakari OT, Reedik M, Reiner AP, Ridker PM, Rudan I, Ryan K, Sarzynski MA, Scott LJ, Scott RA, Sidney S, Siggeirsdottir K, Smith AV, Smith JA, Sonestedt E, Strøm M, Tai ES, Teo KK, Thorand B, Tönjes A, Tremblay A, Uitterlinden AG, Vangipurapu J, van Schoor N, Völker U, Willemsen G, Williams K, Wong Q, Xu H, Young KL, Yuan JM, Zillikens MC, Zonderman AB, Ameur A, Bandinelli S, Bis JC, Boehnke M, Bouchard C, Chasman DI, Smith GD, de Geus EJC, Deldicque L, Dörr M, Evans MK, Ferrucci L, Fornage M, Fox C, Garland T Jr, Gudnason V, Gyllensten U, Hansen T, Hayward C, Horta BL, Hyppönen E, Jarvelin MR, Johnson WC, Kardia SLR, Kiemeney LA, Laakso M, Langenberg C, Lehtimäki T, Marchand LL, Lifelines Cohort Study, Magnusson PKE, Martin NG, Melbye M, Metspalu A, Meyre D, North KE, Ohlsson C, Oldehinkel AJ, Orho-Melander M, Pare G, Park T, Pedersen O, Penninx BWJH, Pers TH, Polasek O, Prokopenko I, Rotimi CN, Samani NJ, Sim X, Snieder H, Sørensen TIA, Spector TD, Timpson NJ, van Dam RM, van der Velde N, van Duijn CM, Vollenweider P, Völzke H, Voortman T, Waeber G, Wareham NJ, Weir DR, Wichmann HE, Wilson JF, Hevener AL, Krook A, Zierath JR, Thomis MAI, Loos RJF, Hoed MD Nature genetics 36071172 Nat Genet 2022 Sep
Mammary duct luminal epithelium controls adipocyte thermogenic programme. Patel S, Sparman NZR, Arneson D, Alvarsson A, Santos LC, Duesman SJ, Centonze A, Hathaway E, Ahn IS, Diamante G, Cely I, Cho CH, Talari NK, Rajbhandari AK, Goedeke L, Wang P, Butte AJ, Blanpain C, Chella Krishnan K, Lusis AJ, Stanley SA, Yang X, Rajbhandari P Nature 37495690 Nature 2023 Aug
Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function. Molendijk J, Blazev R, Mills RJ, Ng YK, Watt KI, Chau D, Gregorevic P, Crouch PJ, Hilton JBW, Lisowski L, Zhang P, Reue K, Lusis AJ, Hudson JE, James DE, Seldin MM, Parker BL eLife 36472367 Elife 2022 Dec 6
Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis. Lee-Ødegård S, Hjorth M, Olsen T, Moen GH, Daubney E, Evans DM, Hevener AL, Lusis AJ, Zhou M, Seldin MM, Allayee H, Hilser J, Viken JK, Gulseth H, Norheim F, Drevon CA, Birkeland KI eLife 39190027 Elife 2024 Aug 27
Conserved multi-tissue transcriptomic adaptations to exercise training in humans and mice. Moore TM, Lee S, Olsen T, Morselli M, Strumwasser AR, Lin AJ, Zhou Z, Abrishami A, Garcia SM, Bribiesca J, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Nguyen CQA, Anand ATS, Yackly A, Mendoza LQ, Leyva BK, Aliman C, Artiga DJ, Meng Y, Charugundla S, Pan C, Jedian V, Seldin MM, Ahn IS, Diamante G, Blencowe M, Yang X, Mouisel E, Pellegrini M, Turcotte LP, Birkeland KI, Norheim F, Drevon CA, Lusis AJ, Hevener AL Cell reports 37178122 Cell Rep 2023 May 30
Barriers in translating preclinical rodent exercise metabolism findings to human health. Fuller KNZ, Thyfault JP Journal of applied physiology (Bethesda, Md. : 1985) 33180643 J Appl Physiol (1985) 2021 Jan 1
Exercise drives metabolic integration between muscle, adipose and liver metabolism and protects against aging-related diseases. Cao X, Thyfault JP Experimental gerontology 37085127 Exp Gerontol 2023 Jun 1
Cognitive impairment caused by compromised hepatic ketogenesis is prevented by endurance exercise. Kelty TJ, Kerr NR, Chou CH, Shryack GE, Taylor CL, Krause AA, Knutson AR, Bunten J, Childs TE, Meers GM, Dashek RJ, Puchalska P, Crawford PA, Thyfault JP, Booth FW, Rector RS The Journal of physiology 39808588 J Physiol 2025 Jan 14
Disruption of hepatic mitochondrial pyruvate and amino acid metabolism impairs gluconeogenesis and endurance exercise capacity in mice. Martino MR, Habibi M, Ferguson D, Brookheart RT, Thyfault JP, Meyer GA, Lantier L, Hughey CC, Finck BN American journal of physiology. Endocrinology and metabolism 38353639 Am J Physiol Endocrinol Metab 2024 Apr 1
Disruption of Hepatic Mitochondrial Pyruvate and Amino Acid Metabolism Impairs Gluconeogenesis and Endurance Exercise Capacity in Mice. Martino MR, Habibi M, Ferguson D, Brookheart RT, Thyfault JP, Meyer GA, Lantier L, Hughey CC, Finck BN bioRxiv : the preprint server for biology 37662392 bioRxiv 2023 Aug 23
Time of Day and Muscle Strength: A Circadian Output? Douglas CM, Hesketh SJ, Esser KA Physiology (Bethesda, Md.) 33325817 Physiology (Bethesda) 2021 Jan 1
Exercise sets the muscle clock with a calcium assist. Wolff CA, Esser KA The Journal of physiology 32949163 J Physiol 2020 Dec
Differential analysis of chromatin accessibility and gene expression profiles identifies cis-regulatory elements in rat adipose and muscle. Nair VD, Vasoya M, Nair V, Smith GR, Pincas H, Ge Y, Douglas CM, Esser KA, Sealfon SC Genomics 34547403 Genomics 2021 Nov
Targeted brain-specific tauopathy compromises peripheral skeletal muscle integrity and function. Alava B, Hery G, Sidhom S, Prokop S, Esser K, Abisambra J bioRxiv : the preprint server for biology 38014109 bioRxiv 2023 Nov 17
Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training. Viggars MR, Berko HE, Hesketh SJ, Wolff CA, Gutierrez-Monreal MA, Martin RA, Jennings IG, Huo Z, Esser KA Molecular metabolism 38950777 Mol Metab 2024 Aug
Clockwork conditioning: Aligning the skeletal muscle clock with time-of-day exercise for cardiometabolic health. Procopio SB, Esser KA Journal of molecular and cellular cardiology 39615287 J Mol Cell Cardiol 2025 Jan
A wrinkle in time: circadian biology in pulmonary vascular health and disease. Bryant AJ, Ebrahimi E, Nguyen A, Wolff CA, Gumz ML, Liu AC, Esser KA American journal of physiology. Lung cellular and molecular physiology 34850650 Am J Physiol Lung Cell Mol Physiol 2022 Jan 1
Optimization of the Omni-ATAC protocol to chromatin accessibility profiling in snap-frozen rat adipose and muscle tissues. Nair VD, Vasoya M, Nair V, Smith GR, Pincas H, Ge Y, Douglas CM, Esser KA, Sealfon SC MethodsX 35464805 MethodsX 2022
Reuniting the Body "Neck Up and Neck Down" to Understand Cognitive Aging: The Nexus of Geroscience and Neuroscience. Hernandez AR, Hoffman JM, Hernandez CM, Cortes CJ, Jumbo-Lucioni P, Baxter MG, Esser KA, Liu AC, McMahon LL, Bizon JL, Burke SN, Buford TW, Carter CS The journals of gerontology. Series A, Biological sciences and medical sciences 34309630 J Gerontol A Biol Sci Med Sci 2022 Jan 7
Fiber-type traps: revisiting common misconceptions about skeletal muscle fiber types with application to motor control, biomechanics, physiology, and biology. Blemker SS, Brooks SV, Esser KA, Saul KR Journal of applied physiology (Bethesda, Md. : 1985) 37994416 J Appl Physiol (1985) 2024 Jan 1
Reinventing the wheel: comparison of two wheel cage styles for assessing mouse voluntary running activity. Seward T, Harfmann BD, Esser KA, Schroder EA Journal of applied physiology (Bethesda, Md. : 1985) 29357507 J Appl Physiol (1985) 2018 Apr 1
Time-of-day dependent effects of contractile activity on the phase of the skeletal muscle clock. Kemler D, Wolff CA, Esser KA The Journal of physiology 32537739 J Physiol 2020 Sep
Time for Exercise? Exercise and Its Influence on the Skeletal Muscle Clock. Martin RA, Esser KA Journal of biological rhythms 36129164 J Biol Rhythms 2022 Dec
Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions. Roberts MD, McCarthy JJ, Hornberger TA, Phillips SM, Mackey AL, Nader GA, Boppart MD, Kavazis AN, Reidy PT, Ogasawara R, Libardi CA, Ugrinowitsch C, Booth FW, Esser KA Physiological reviews 37382939 Physiol Rev 2023 Oct 1
Metabolism and exercise: the skeletal muscle clock takes centre stage. Martin RA, Viggars MR, Esser KA Nature reviews. Endocrinology 36726017 Nat Rev Endocrinol 2023 May
Early morning run-training results in enhanced endurance performance adaptations in mice. Hesketh SJ, Sexton CL, Wolff CA, Viggars MR, Esser KA bioRxiv : the preprint server for biology 37781623 bioRxiv 2023 Sep 19
Exploring Circadian Changes in Muscle Physiology: Methodological Considerations. Viggars MR, Esser KA Function (Oxford, England) 39227174 Function (Oxf) 2024 Nov 20
Exercise Timing and Circadian Rhythms. Wolff CA, Esser KA Current opinion in physiology 31938759 Curr Opin Physiol 2019 Aug
Ticking for Metabolic Health: The Skeletal-Muscle Clocks. Gutierrez-Monreal MA, Harmsen JF, Schrauwen P, Esser KA Obesity (Silver Spring, Md.) 32468732 Obesity (Silver Spring) 2020 Jul
Targeted brain-specific tauopathy compromises peripheral skeletal muscle integrity and function. Alava B, Hery G, Sidhom S, Gutierrez-Monreal M, Prokop S, Esser KA, Abisambra J Aging brain 38419621 Aging Brain 2024

This page last reviewed on March 17, 2025