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Funded Research

The Regenerative Medicine program has transitioned from Common Fund support. For more information, please visit https://commonfund.nih.gov/stemcells.

Please note that since the Regenerative Medicine Program is no longer supported by the Common Fund, the program website is being maintained as an archive and will not be updated on a regular basis.

2014 NIH CRM Therapeutic Challenge Award
PI NameInstitution NameTitle
BHARTI, KAPILNATIONAL EYE INSTITUTEAn Autologous Cell Based Therapy Using iPS Cell-Derived RPE

 

2012 NIH CRM Pilot Projects for Clinical Applications
PI NameInstitution NameTitle
BONNEMANN, CARSTENNATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKEUsing iPSC to model the neurological phenotype of alpha-dystroglycanopathie
LIANG, T. JAKENATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESiPSC-derived Human Hepatocytes: A Model for Treatment of Liver Disease
LIU, PAUL P.NATIONAL HUMAN GENOME RESEARCH INSTITUTETowards cell therapy for FPD/AML with patient-specific iPS cells
MILLER, SHELDONNATIONAL EYE INSTITUTEConstructing Functional iPSC-derived RPE Tissue for Cell-based Therapy
RESTIFO, NICHOLASNATIONAL CANCER INSTITUTERegenerative medicine using lineage reprogramming of tumor-specific T cells
USDIN, KARENNATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESMaking neurons from FX iPSCs to study disease pathology and to screen for drugs

 

2011 NIH CRM Pilot Projects for Clinical Applications
PI NameInstitution NameTitle
BOEHM, MANFREDNATIONAL HEART, LUNG, AND BLOOD INSTITUTEReprogramming and lineage differentiations of IPS cells from HIES patients
DENG, CHUXIANATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESTargeted correction of human and mouse iPS cells for liver diseases
DUNBAR, CYNTHIANATIONAL HEART, LUNG, AND BLOOD INSTITUTEPreclinical Development of reprogrammed cells utilizing the rhesus macaque
FISCHBECK, KENNETHNATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKEAn iPS cell system for the study of motor neuron disease
JETTEN, ANTONNATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCESInduction of pancreatic beta cell development in iPS cells by GLIS3
MALECH, HARRYNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESGene Repaired Autologous iPSC to treat Chronic Granulomatous Disease
MILLER, SHELDONNATIONAL EYE INSTITUTEMechanisms of AMD Initiation Using iPS Cell-Derived RPE
PARK, JOHNNATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKEStimulation of anti-glioma immune responses by iPS cell-derived microglia
SARTORELLI, VITTORIONATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASESRole of Epigenetic Regulators in iPS and SCNT-derived ESCs
SIDRANSKY, ELLENNATIONAL HUMAN GENOME RESEARCH INSTITUTEiPSc to study and treat Gaucher disease and associated parkinsonism
SWAROOP, ANANDNATIONAL EYE INSTITUTETherapies for early onset retinal degeneration using iPS cell technology
WESTPHAL, HEINERNATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENTiPS cells for the analysis and treatment of SLOS, a rare childhood disorder
YOUNG, NEALNATIONAL HEART, LUNG, AND BLOOD INSTITUTEInduced pluripotent stem cells to model telomere regulation and cell therapy



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2010 NIH CRM Pilot Projects for Clinical Applications
PI NameInstitution NameTitle
AUSTIN, CHRISTOPHERNATIONAL HUMAN GENOME RESEARCH INSTITUTEDevelopment of iPS Cell-Based Disease Model of Niemann-Pick Disease Type C
BOHELER, KENNETHNATIONAL INSTITUTE OF AGINGIsolation of "homogeneous" human iPS cell populations
FINKEL, TORENNATIONAL HEART, LUNG, AND BLOOD INSTITUTECardiovascular Applications of iPS Cells
FISCHBECK, KENNETHNATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKEiPS cells for mechanistic and therapeutic studies of motor neuron disease
KELLEY, MATTHEWNATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERSInduction of hair cell regeneration using induced pluripotent stem cells
KUEHN, MICHAELNATIONAL CANCER INSTITUTEAssessing the Smads2/3 dependent epigenetic landscape in iPSC
LIU, PAUL PNATIONAL HUMAN GENOME RESEARCH INSTITUTEDevelopment of a Reference Set of Comprehensively Characterized iPS cell li
MILLER, SHELDONNATIONAL EYE INSTITUTERestoring Vision: Criteria for iPS Cell Derived Retinal Pigment Epithelia
RESTIFO, NICHOLASNATIONAL CANCER INSTITUTEReprogramming tumor-specific T cells using iPS for cancer immunotherapy
ROBEY, PAMELANATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCHDifferentiation of human iPSCs into bone and cartilage
WEINBERGER, DANIELNATIONAL INSTITUTE OF MENTAL HEALTHValidation of human GABA inter-neurons derived from iPS cells

This page last reviewed on April 12, 2024