Funded Research
|
2012 NIH CRM Pilot Projects for Clinical Applications |
||
| PI Name | Institution Name | Title |
|---|---|---|
|
BONNEMANN, CARSTEN |
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE |
Using iPSC to model the neurological phenotype of alpha-dystroglycanopathie |
|
LIANG, T. JAKE |
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
iPSC-derived Human Hepatocytes: A Model for Treatment of Liver Disease |
|
LIU, PAUL P. |
NATIONAL HUMAN GENOME RESEARCH INSTITUTE |
Towards cell therapy for FPD/AML with patient-specific iPS cells |
|
MILLER, SHELDON |
NATIONAL EYE INSTITUTE |
Constructing Functional iPSC-derived RPE Tissue for Cell-based Therapy |
|
RESTIFO, NICHOLAS |
NATIONAL CANCER INSTITUTE |
Regenerative medicine using lineage reprogramming of tumor-specific T cells |
|
USDIN, KAREN |
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
Making neurons from FX iPSCs to study disease pathology and to screen for drugs |
| 2011 NIH CRM Pilot Projects for Clinical Applications | ||
| PI Name | Institution Name | Title |
|---|---|---|
| BOEHM, MANFRED | NATIONAL HEART, LUNG, AND BLOOD INSTITUTE | Reprogramming and lineage differentiations of IPS cells from HIES patients |
| DENG, CHUXIA | NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES | Targeted correction of human and mouse iPS cells for liver diseases |
| DUNBAR, CYNTHIA | NATIONAL HEART, LUNG, AND BLOOD INSTITUTE | Preclinical Development of reprogrammed cells utilizing the rhesus macaque |
| FISCHBECK, KENNETH | NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE | An iPS cell system for the study of motor neuron disease |
| JETTEN, ANTON | NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES | Induction of pancreatic beta cell development in iPS cells by GLIS3 |
| MALECH, HARRY | NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES | Gene Repaired Autologous iPSC to treat Chronic Granulomatous Disease |
| MILLER, SHELDON | NATIONAL EYE INSTITUTE | Mechanisms of AMD Initiation Using iPS Cell-Derived RPE |
| PARK, JOHN | NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE | Stimulation of anti-glioma immune responses by iPS cell-derived microglia |
| SARTORELLI, VITTORIO | NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES | Role of Epigenetic Regulators in iPS and SCNT-derived ESCs |
| SIDRANSKY, ELLEN | NATIONAL HUMAN GENOME RESEARCH INSTITUTE | iPSc to study and treat Gaucher disease and associated parkinsonism |
| SWAROOP, ANAND | NATIONAL EYE INSTITUTE | Therapies for early onset retinal degeneration using iPS cell technology |
| WESTPHAL, HEINER | NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT | iPS cells for the analysis and treatment of SLOS, a rare childhood disorder |
| YOUNG, NEAL | NATIONAL HEART, LUNG, AND BLOOD INSTITUTE | Induced pluripotent stem cells to model telomere regulation and cell therapy |
| 2010 NIH CRM Pilot Projects for Clinical Applications | ||
| PI Name | Institution Name | Title |
|---|---|---|
| AUSTIN, CHRISTOPHER | NATIONAL HUMAN GENOME RESEARCH INSTITUTE | Development of iPS Cell-Based Disease Model of Niemann-Pick Disease Type C |
| BOHELER, KENNETH | NATIONAL INSTITUTE OF AGING | Isolation of "homogeneous" human iPS cell populations |
| FINKEL, TOREN | NATIONAL HEART, LUNG, AND BLOOD INSTITUTE | Cardiovascular Applications of iPS Cells |
| FISCHBECK, KENNETH | NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE | iPS cells for mechanistic and therapeutic studies of motor neuron disease |
| KELLEY, MATTHEW | NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS | Induction of hair cell regeneration using induced pluripotent stem cells |
| KUEHN, MICHAEL | NATIONAL CANCER INSTITUTE | Assessing the Smads2/3 dependent epigenetic landscape in iPSC |
| LIU, PAUL P | NATIONAL HUMAN GENOME RESEARCH INSTITUTE | Development of a Reference Set of Comprehensively Characterized iPS cell li |
| MILLER, SHELDON | NATIONAL EYE INSTITUTE | Restoring Vision: Criteria for iPS Cell Derived Retinal Pigment Epithelia |
| RESTIFO, NICHOLAS | NATIONAL CANCER INSTITUTE | Reprogramming tumor-specific T cells using iPS for cancer immunotherapy |
| ROBEY, PAMELA | NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH | Differentiation of human iPSCs into bone and cartilage |
| WEINBERGER, DANIEL | NATIONAL INSTITUTE OF MENTAL HEALTH | Validation of human GABA inter-neurons derived from iPS cells |
