SMaHT Funded Research

Funded Research

Somatic Mosaicism across Human Tissues (SMaHT) Program: Organizational Center (U24 Clinical Trial Not Allowed) RFA-RM-22-009
PI Name Institution Name Title
WANG, TING (contact) 
FULTON, LUCINDA
LAWSON, HEATHER A		 WASHINGTON UNIVERSITY WashU Somatic Mosaicism across Human Tissues (SMaHT) Program Organizational Center
Somatic Mosaicism across Human Tissues (SMaHT) Program: Data Analysis Center (UM1 Clinical Trial Not Allowed) RFA-RM-22-010
 
PI Name Institution Name Title
PARK, PETER J HARVARD MEDICAL SCHOOL Data Analysis Center for Somatic Mosaicism Across Human Tissues Network
Somatic Mosaicism across Human Tissues (SMaHT) Program:  Tool Development Projects (UG3/UH3 Clinical Trial Not Allowed) RFA-RM-22-011
PI Name Institution Name Title

ABYZOV, ALEXEJ

 MAYO CLINIC ROCHESTER Hybrid approach for comprehensive mutation detection in a cell
BURNS, KATHLEEN H (contact)
LEE, EUNJUNG ALICE		 DANA-FARBER CANCER INST Single molecule detection of L1 insertions and intermediates
CHEN, FEI (contact)
BUENROSTRO, JASON DANIEL
GETZ, GAD A		 BROAD INSTITUTE, INC. A platform for scalable spatial somatic variant profiling
CHOUDHURY, SANGITA (contact)
LEE, EUNJUNG ALICE
WALSH, CHRISTOPHER A		 BOSTON CHILDREN'S HOSPITAL Detection and Characterization of somatic mutations in human tissue utilizing duplex-consensus sequencing
EVRONY, GILAD DAVID NEW YORK UNIVERSITY SCHOOL OF MEDICINE Ultra-high fidelity single-molecule profiling of mosaic double- and single-strand DNA mutations and damage
FAZZIO, THOMAS G (contact)
GARBER, MANUEL		 UNIV OF MASSACHUSETTS MED SCH WORCESTER varCUT&Tag: a method for simultaneous identification and characterization of sequence variants in regulatory elements and genes
JIN, FULAI (contact)
LI, YAN		 CASE WESTERN RESERVE UNIVERSITY Simultaneous mapping of somatic mosaicism and kb-resolution 3D genome in single cells.
LANDAU, DAN (contact)
SATIJA, RAHUL		 WEILL MEDICAL COLL OF CORNELL UNIV Single-cell multi-omics to link clonal mosaicism (CM) genotypes with chromatin, epigenomic, transcriptomic and protein phenotypes
MARTH, GABOR T (contact)
UNDERHILL, HUNTER REEVE		 UNIVERSITY OF UTAH A reference-free computational algorithm for comprehensive somatic mosaic mutation detection

 
MILLS, RYAN E (contact)
BOYLE, ALAN P
MCCONNELL, MICHAEL J		 UNIVERSITY OF MICHIGAN AT ANN ARBOR Molecular and Computational Tools for Identifying Somatic Mosaicism in Human Tissues
 
SEDLAZECK, FRITZ J (contact)
WU, TAO		 BAYLOR COLLEGE OF MEDICINE Identification of somatic/ mosaic SV and transposon activity and their crosstalk to DNA epigenetic Modifications
 
URBAN, ALEXANDER ECKEHART STANFORD UNIVERSITY Establishing and benchmarking advanced methods to comprehensively characterize somatic genome variation in single human cells
WALSH, CHRISTOPHER A (contact)
PARK, PETER J		 BOSTON CHILDREN'S HOSPITAL Development of an efficient high throughput technique for the identification of high-impact non-coding somatic variants across multiple tissue types
 
ZONG, CHENGHANG BAYLOR COLLEGE OF MEDICINE Develop accurate high-coverage and high-throughput single-cell Duplex-seq chemistry and multi-omics platforms for simultaneous profiling of somatic mutation and the transcriptome in single human cells

 

Somatic Mosaicism across Human Tissues (SMaHT) Program: Tissue Procurement Center (U24 Clinical Trial Not Allowed) RFA-RM-22-012
PI Name Institution Name Title
BELL, THOMAS J NATIONAL DISEASE RESEARCH INTERCHANGE Tissue Procurement Center (TPC) Supporting the Somatic Mosaicism across Human Tissues (SMaHT) Network
Somatic Mosaicism across Human Tissues (SMaHT) Program: Genome Characterization Centers (UM1 Clinical Trial Not Allowed) RFA-RM-22-013
PI Name Institution Name Title

ARDLIE, KRISTIN (contact)
LENNON, NIALL JOHN
NATARAJAN, PRADEEP

 BROAD INSTITUTE, INC. Whole Individual Comprehensive KnowlEDge: Somatic Mosaicism across Human Tissues (WICKed SMaHT)
BENNETT, JAMES T (contact)
EICHLER, EVAN
STERGACHIS, ANDREW BEN		 SEATTLE CHILDREN'S HOSPITAL Mosaicism in Human Tissues, from Telomere to Telomere to RFA-22-013: Somatic Mosaicism across Human Tissues Program: Genome Characterization Centers.
 
GERMER, SOREN (contact)
APARICIO, SAMUEL    		 NEW YORK GENOME CENTER     New York Genome Characterization Center: Somatic Mosaicism across Human Tissues
GIBBS, RICHARD A (contact)
CHEN, RUI
DODDAPANENI, HARSHA VARDHAN		 BAYLOR COLLEGE OF  MEDICINE Comprehensive Somatic Variant Characterization at the HGSC
WANG, TING (contact)
FULTON, ROBERT SCOTT
SHEN, HUI		 WASHINGTON UNIVERSITY WashU-VAI Somatic Mosaicism across Human Tissues (SMaHT) Program Genome Characterization Center

This page last reviewed on May 11, 2023