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Funded Research

Cellular Senescence Network: Technology Development and Application in Murine Systems (UG3/UH3 Clinical Trial Not Allowed) RFA-RM-22-005 In September 2024, the awards below transitioned into their UH3 phase. The UG3 (first phase) of these awards focused on technology development and feasibility, while the UH3 phase will focus on technology application.
PI NameInstitution NameTitle
SCHAFER, MARISSA JOYMAYO CLINIC ROCHESTERSpatially-resolved protein and transcriptome mapping of senescent cells

 

Cellular Senescence Network: Technology Development and Application in Human Systems (UG3/UH3 Clinical Trial Not Allowed RFA-RM-22-004. In September 2024, the awards below transitioned into their UH3 phase. The UG3 (first phase) of these awards focused on technology development and feasibility, while the UH3 phase will focus on technology application.
PI NameInstitution NameTitle
CHRISTIANO, ANGELA MCOLUMBIA UNIVERSITY HEALTH SCIENCESSenescence-on-a-chip: Building a microphysiological 3D skin model
SO, PETER TMASSACHUSETTS INSTITUTE OF TECHNOLOGYSingle-cell label-free identification of senescence by Raman microscopy and spatial genomics
WU, PEI-HSUNJOHNS HOPKINS UNIVERSITYThree-dimensional maps of senescence in the human pancreas

 

Cellular Senescence Network: Murine Tissue Mapping Centers (U54 - Clinical Trial Not Allowed) RFA-RM-22-003
PI NameInstitution NameTitle
ADAMS, PETER D (contact)
REN, BING
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY  INSTITUTESpatial mapping senescent cells across the mouse lifespan by multiplex transcriptomics and epigenomics
BERNLOHR, DAVID A (contact)
BUDINGER, GR SCOTT
KHOSLA, SUNDEEP
UNIVERSITY OF MINNESOTAMidwest Murine-Tissue Mapping Center (MM-TMC)
DIXIT, VISHWA DEEP (contact)
MONTGOMERY, RUTH R
YALE UNIVERSITYYale Murine-TMC on Immune Cell Senescence Derived Inflammation
ELISSEEFF, JENNIFER H (contact)
BAKER, DARREN
DE CABO, RAFAEL
JOHNS HOPKINS UNIVERSITYJHU-Mayo-NIA Murine Senescence Mapping Program (JMN-MSMP)
ROSENTHAL, NADIA A (contact)
KORSTANJE, RONNY
ROBSON, PAUL
XU, MING
JACKSON LABORATORYThe Jackson Laboratory Senescence Tissue Mapping Center (JAX-Sen TMC)

 

Cellular Senescence Network: Consortium Organization and Data Coordinating Center (U24 Clinical Trial Not Allowed) RFA-RM-21-010
PI NameInstitution NameTitle
SILVERSTEIN, JONATHAN C (contact)
BAR-JOSEPH, ZIV
BLOOD, PHILIP D
UNIVERSITY OF PITTSBURGH AT PITTSBURGHCellular Senescence Network (SenNet) Consortium Organization and Data Coordinating Center (CODCC)

 

Cellular Senescence Network: Technology Development and Application (UG3/UH3 Clinical Trial Not Allowed) RFA-RM-21-009
PI NameInstitution NameTitle
DALDRUP-LINK, HEIKE ELIZABETHSTANFORD UNIVERSITYCellular Senescence Network: New Imaging Tools for Arthritis Imaging
DOU, ZHIXUN (contact)
RAJAGOPAL, JAYARAJ
SLAVOV, NIKOLAI
MASSACHUSETTS GENERAL HOSPITALSingle-cell proteomic identification of novel markers of senescence
GU, LIANGCAIUNIVERSITY OF WASHINGTONPIXEL-seq-based spatial, multi-omic profiling for senescent cell mapping with single-cell resolution
LEE, JUN HEEUNIVERSITY OF MICHIGAN AT ANN ARBORSeq-Scope: Microscopic Examination of Spatial Single Cell Transcriptome in Cell and Tissue Senescence
MELOV, SIMONBUCK INSTITUTE FOR RESEARCH ON AGINGEvaluating diverse technologies for detecting and validating senescent cells in vivo
NERETTI, NICOLA (contact)
MA, JIAN
WANG, SIYUAN
BROWN UNIVERSITYSpatial omics technologies to map the senescent cell microenvironment
PASSOS, JOAOMAYO CLINIC ROCHESTERDevelopment of machine learning software to quantitatively map telomere induced senescence in tissue sections during aging

 

Cellular Senescence Network: Tissue Mapping Centers (U54 Clinical Trial Not Allowed) RFA-RM-21-008
PI NameInstitution NameTitle
CAMPISI, JUDITH (contact)
SCHILLING, BIRGIT
BUCK INSTITUTE FOR RESEARCH ON AGINGSenescent cell mapping, identification and validation for human somatic and reproductive tissues
DING, LI (contact)
CHEN, FENG
FIELDS, RYAN C
STEWART, SHEILA A
WASHINGTON UNIVERSITYWashington University Senescence Tissue Mapping Center (WU-SN-TMC)
FAN, RONG (contact)
HALENE, STEPHANIE
YALE UNIVERSITY Yale TMC for Cellular Senescence in Lymphoid Organs
FINKEL, TOREN (contact)
KOENIGSHOFF, MELANIE
MORA, ANA LUCIA
RAHMAN, IRFAN
UNIVERSITY OF PITTSBURGH AT PITTSBURGHTriState SenNET (Lung and Heart) Tissue Map and Atlas consortium
KUCHEL, GEORGE A (contact)
GAROVIC, VESNA D
MUSI, NICOLAS
ROBSON, PAUL
UNIVERSITY OF CONNECTICUT SCH OF MED/DNTThe KAPP-Sen Tissue Mapping Center Collaborative
LEE, PATTY JDUKE UNIVERSITYThe Duke Senescent Cell Evaluations in Normal Tissues (SCENT) Mapping Center
NIEDERNHOFER, LAURA JANEUNIVERSITY OF MINNESOTAMinnesota Tissue Mapping Center for Senescent Cells
PHATNANI, HEMALI (contact)
CHRISTIANO, ANGELA M
MENON, VILAS
SUH, YOUSIN
COLUMBIA UNIVERSITY HEALTH SCIENCESA Multi-scale Atlas of Senescence in Diverse Tissue Types

 

This page last reviewed on December 3, 2024