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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
| Title | Author | Journal Name | PubMedID | Journal Abbreviation | Publication Date | PubMedLink |
|---|---|---|---|---|---|---|
| Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase. | Puthenveetil S, Liu DS, White KA, Thompson S, Ting AY | Journal of the American Chemical Society | 19863063 | J Am Chem Soc | 2009 Nov 18 | https://www.ncbi.nlm.nih.gov/pubmed/19863063 |
| Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease. | Connelly JP, Barker JC, Pruett-Miller S, Porteus MH | Molecular therapy : the journal of the American Society of Gene Therapy | 20389291 | Mol Ther | 2010 Jun | https://www.ncbi.nlm.nih.gov/pubmed/20389291 |
| Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells. | Ha K, Takeda Y, Dynan WS | DNA repair | 21144806 | DNA Repair (Amst) | 2011 Mar 7 | https://www.ncbi.nlm.nih.gov/pubmed/21144806 |
| Bright and compact alloyed quantum dots with broadly tunable near-infrared absorption and fluorescence spectra through mercury cation exchange. | Smith AM, Nie S | Journal of the American Chemical Society | 21142154 | J Am Chem Soc | 2011 Jan 12 | https://www.ncbi.nlm.nih.gov/pubmed/21142154 |
| Imaging dynamic cellular events with quantum dots The bright future. | Smith AM, Wen MM, Nie S | The biochemist | 20824157 | Biochem (Lond) | 2010 Jun 1 | https://www.ncbi.nlm.nih.gov/pubmed/20824157 |
| Bioconjugated quantum dots for in vivo molecular and cellular imaging. | Smith AM, Duan H, Mohs AM, Nie S | Advanced drug delivery reviews | 18495291 | Adv Drug Deliv Rev | 2008 Aug 17 | https://www.ncbi.nlm.nih.gov/pubmed/18495291 |
| Chromatin dynamics and gene positioning. | Kumaran RI, Thakar R, Spector DL | Cell | 18358806 | Cell | 2008 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/18358806 |
| Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice. | Meiler SE, Wade M, Kutlar F, Yerigenahally SD, Xue Y, Moutouh-de Parseval LA, Corral LG, Swerdlow PS, Kutlar A | Blood | 21536862 | Blood | 2011 Jul 28 | https://www.ncbi.nlm.nih.gov/pubmed/21536862 |
| Imaging and tracking of tat peptide-conjugated quantum dots in living cells: new insights into nanoparticle uptake, intracellular transport, and vesicle shedding. | Ruan G, Agrawal A, Marcus AI, Nie S | Journal of the American Chemical Society | 17983227 | J Am Chem Soc | 2007 Nov 28 | https://www.ncbi.nlm.nih.gov/pubmed/17983227 |
| Tuning the optical and electronic properties of colloidal nanocrystals by lattice strain. | Smith AM, Mohs AM, Nie S | Nature nanotechnology | 19119284 | Nat Nanotechnol | 2009 Jan | https://www.ncbi.nlm.nih.gov/pubmed/19119284 |
| Long noncoding RNAs: functional surprises from the RNA world. | Wilusz JE, Sunwoo H, Spector DL | Genes & development | 19571179 | Genes Dev | 2009 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/19571179 |
| Semiconductor nanocrystals: structure, properties, and band gap engineering. | Smith AM, Nie S | Accounts of chemical research | 19827808 | Acc Chem Res | 2010 Feb 16 | https://www.ncbi.nlm.nih.gov/pubmed/19827808 |
| Homologous recombination-based gene therapy for the primary immunodeficiencies. | Porteus M | Annals of the New York Academy of Sciences | 22236437 | Ann N Y Acad Sci | 2011 Dec | https://www.ncbi.nlm.nih.gov/pubmed/22236437 |
| Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level. | Kita A, Sakurai Y, Myers DR, Rounsevell R, Huang JN, Seok TJ, Yu K, Wu MC, Fletcher DA, Lam WA | PloS one | 22028878 | PLoS One | 2011 | https://www.ncbi.nlm.nih.gov/pubmed/22028878 |
| Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing. | Hendel A, Kildebeck EJ, Fine EJ, Clark J, Punjya N, Sebastiano V, Bao G, Porteus MH | Cell reports | 24685129 | Cell Rep | 2014 Apr 10 | https://www.ncbi.nlm.nih.gov/pubmed/24685129 |
| Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation. | Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino RG, Tran R, Ahn B, Hardy ET, Kee MF, Kumar S, Bao G, Barker TH, Lam WA | Proceedings of the National Academy of Sciences of the United States of America | 25246564 | Proc Natl Acad Sci U S A | 2014 Oct 7 | https://www.ncbi.nlm.nih.gov/pubmed/25246564 |
| CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity. | Cradick TJ, Fine EJ, Antico CJ, Bao G | Nucleic acids research | 23939622 | Nucleic Acids Res | 2013 Nov | https://www.ncbi.nlm.nih.gov/pubmed/23939622 |
| Receptor-mediated delivery of engineered nucleases for genome modification. | Chen Z, Jaafar L, Agyekum DG, Xiao H, Wade MF, Kumaran RI, Spector DL, Bao G, Porteus MH, Dynan WS, Meiler SE | Nucleic acids research | 23956220 | Nucleic Acids Res | 2013 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23956220 |
| DNA targeting specificity of RNA-guided Cas9 nucleases. | Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F | Nature biotechnology | 23873081 | Nat Biotechnol | 2013 Sep | https://www.ncbi.nlm.nih.gov/pubmed/23873081 |
| Engineering imaging probes and molecular machines for nanomedicine. | Tong S, Cradick TJ, Ma Y, Dai Z, Bao G | Science China. Life sciences | 23108862 | Sci China Life Sci | 2012 Oct | https://www.ncbi.nlm.nih.gov/pubmed/23108862 |
| Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells. | Hendel A, Bak RO, Clark JT, Kennedy AB, Ryan DE, Roy S, Steinfeld I, Lunstad BD, Kaiser RJ, Wilkens AB, Bacchetta R, Tsalenko A, Dellinger D, Bruhn L, Porteus MH | Nature biotechnology | 26121415 | Nat Biotechnol | 2015 Sep | https://www.ncbi.nlm.nih.gov/pubmed/26121415 |
| Genome Editing: A New Approach to Human Therapeutics. | Porteus M | Annual review of pharmacology and toxicology | 26566154 | Annu Rev Pharmacol Toxicol | 2016 | https://www.ncbi.nlm.nih.gov/pubmed/26566154 |
| TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs. | Suzuki S, Sargent RG, Illek B, Fischer H, Esmaeili-Shandiz A, Yezzi MJ, Lee A, Yang Y, Kim S, Renz P, Qi Z, Yu J, Muench MO, Beyer AI, Guimarães AO, Ye L, Chang J, Fine EJ, Cradick TJ, Bao G, Rahdar M, Porteus MH, Shuto T, Kai H, Kan YW, Gruenert DC | Molecular therapy. Nucleic acids | 26730810 | Mol Ther Nucleic Acids | 2016 Jan 5 | https://www.ncbi.nlm.nih.gov/pubmed/26730810 |
| Intracellular delivery of molecules using microfabricated nanoneedle arrays. | Park S, Choi SO, Paik SJ, Choi S, Allen M, Prausnitz M | Biomedical microdevices | 26797026 | Biomed Microdevices | 2016 Feb | https://www.ncbi.nlm.nih.gov/pubmed/26797026 |
| A multifunctional AAV-CRISPR-Cas9 and its host response. | Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM | Nature methods | 27595405 | Nat Methods | 2016 Oct | https://www.ncbi.nlm.nih.gov/pubmed/27595405 |
| Treating hemoglobinopathies using gene-correction approaches: promises and challenges. | Cottle RN, Lee CM, Bao G | Human genetics | 27314256 | Hum Genet | 2016 Sep | https://www.ncbi.nlm.nih.gov/pubmed/27314256 |
| Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection. | Cottle RN, Lee CM, Archer D, Bao G | Scientific reports | 26558999 | Sci Rep | 2015 Nov 12 | https://www.ncbi.nlm.nih.gov/pubmed/26558999 |
| Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease. | Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin JF, Bao G, Lagor WR | Scientific reports | 28300165 | Sci Rep | 2017 Mar 16 | https://www.ncbi.nlm.nih.gov/pubmed/28300165 |
| Spatial control of in vivo CRISPR-Cas9 genome editing via nanomagnets. | Zhu H, Zhang L, Tong S, Lee CM, Deshmukh H, Bao G | Nature biomedical engineering | 30944431 | Nat Biomed Eng | 2019 Feb | https://www.ncbi.nlm.nih.gov/pubmed/30944431 |
| Nonrigid registration of 2-D and 3-D dynamic cell nuclei images for improved classification of subcellular particle motion. | Kim IH, Chen YC, Spector DL, Eils R, Rohr K | IEEE transactions on image processing : a publication of the IEEE Signal Processing Society | 20840894 | IEEE Trans Image Process | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/20840894 |
| Protein Mechanics: A New Frontier in Biomechanics. | Bao G | Experimental mechanics | 19809588 | Exp Mech | 2009 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/19809588 |
| Bioimaging: second window for in vivo imaging. | Smith AM, Mancini MC, Nie S | Nature nanotechnology | 19898521 | Nat Nanotechnol | 2009 Nov | https://www.ncbi.nlm.nih.gov/pubmed/19898521 |
| Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications. | Li S, Nguyen L, Xiong H, Wang M, Hu TC, She JX, Serkiz SM, Wicks GG, Dynan WS | Nanomedicine : nanotechnology, biology, and medicine | 19616128 | Nanomedicine | 2010 Feb | https://www.ncbi.nlm.nih.gov/pubmed/19616128 |
| Chromatin dynamics. | Hübner MR, Spector DL | Annual review of biophysics | 20462379 | Annu Rev Biophys | 2010 | https://www.ncbi.nlm.nih.gov/pubmed/20462379 |
| Next-generation quantum dots. | Smith AM, Nie S | Nature biotechnology | 19668181 | Nat Biotechnol | 2009 Aug | https://www.ncbi.nlm.nih.gov/pubmed/19668181 |
| Intranuclear delivery of a novel antibody-derived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit. | Xiong H, Lee RJ, Haura EB, Edwards JG, Dynan WS, Li S | International journal of radiation oncology, biology, physics | 22138455 | Int J Radiat Oncol Biol Phys | 2012 Jul 1 | https://www.ncbi.nlm.nih.gov/pubmed/22138455 |
| NANOSTRUCTURED PROBES FOR IN VIVO GENE DETECTION. | Bao G, Santangelo P, Nitin N, Rhee WJ | Nanomedicine : design and applications of magnetic nanomaterials, nanosensors, and nanosystems | 22138717 | Nanomedicine (Chichester) | 2010 | https://www.ncbi.nlm.nih.gov/pubmed/22138717 |
| In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology. | Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, Ware RE, Fletcher DA, Lam WA | The Journal of clinical investigation | 22156199 | J Clin Invest | 2012 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22156199 |
| Quantum dot-fluorescent protein FRET probes for sensing intracellular pH. | Dennis AM, Rhee WJ, Sotto D, Dublin SN, Bao G | ACS nano | 22443420 | ACS Nano | 2012 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/22443420 |
| Drug delivery: Puncturing cells en masse. | Prausnitz MR | Nature materials | 25899907 | Nat Mater | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25899907 |
| Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector. | Abarrategui-Pontes C, Créneguy A, Thinard R, Fine EJ, Thepenier V, Fournier le RL, Cradick TJ, Bao G, Tesson L, Podevin G, Anegon I, Nguyen TH | Current gene therapy | 25687502 | Curr Gene Ther | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/25687502 |
| Examination of CRISPR/Cas9 design tools and the effect of target site accessibility on Cas9 activity. | Lee CM, Davis TH, Bao G | Experimental physiology | 28303677 | Exp Physiol | 2018 Apr 1 | https://www.ncbi.nlm.nih.gov/pubmed/28303677 |
| Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6. | Bak RO, Dever DP, Reinisch A, Cruz Hernandez D, Majeti R, Porteus MH | eLife | 28956530 | Elife | 2017 Sep 28 | https://www.ncbi.nlm.nih.gov/pubmed/28956530 |
| Understanding and re-engineering nucleoprotein machines to cure human disease. | Dynan W, Takeda Y, Roth D, Bao G | Nanomedicine (London, England) | 18393669 | Nanomedicine (Lond) | 2008 Feb | https://www.ncbi.nlm.nih.gov/pubmed/18393669 |
| E. coli expression of a soluble, active single-chain antibody variable fragment containing a nuclear localization signal. | Xiong H, Li S, Yang Z, Burgess RR, Dynan WS | Protein expression and purification | 19281848 | Protein Expr Purif | 2009 Aug | https://www.ncbi.nlm.nih.gov/pubmed/19281848 |
| Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis. | Rowe RG, Wang LD, Coma S, Han A, Mathieu R, Pearson DS, Ross S, Sousa P, Nguyen PT, Rodriguez A, Wagers AJ, Daley GQ | The Journal of experimental medicine | 27401346 | J Exp Med | 2016 Jul 25 | https://www.ncbi.nlm.nih.gov/pubmed/27401346 |
| COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites. | Cradick TJ, Qiu P, Lee CM, Fine EJ, Bao G | Molecular therapy. Nucleic acids | 25462530 | Mol Ther Nucleic Acids | 2014 Dec 2 | https://www.ncbi.nlm.nih.gov/pubmed/25462530 |
| Multifunctional nanoparticles for drug delivery and molecular imaging. | Bao G, Mitragotri S, Tong S | Annual review of biomedical engineering | 23642243 | Annu Rev Biomed Eng | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23642243 |
| An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage. | Fine EJ, Cradick TJ, Zhao CL, Lin Y, Bao G | Nucleic acids research | 24381193 | Nucleic Acids Res | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24381193 |
| Nanomedicine: tiny particles and machines give huge gains. | Tong S, Fine EJ, Lin Y, Cradick TJ, Bao G | Annals of biomedical engineering | 24297494 | Ann Biomed Eng | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24297494 |
| Chromatin meets its organizers. | Bodnar MS, Spector DL | Cell | 23746835 | Cell | 2013 Jun 6 | https://www.ncbi.nlm.nih.gov/pubmed/23746835 |
| Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models. | Fine EJ, Cradick TJ, Bao G | Methods in molecular biology (Clifton, N.J.) | 24557916 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24557916 |
| TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity. | Mussolino C, Alzubi J, Fine EJ, Morbitzer R, Cradick TJ, Lahaye T, Bao G, Cathomen T | Nucleic acids research | 24792154 | Nucleic Acids Res | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24792154 |
| CRISPR/Cas9 Genome Engineering in Engraftable Human Brain-Derived Neural Stem Cells. | Dever DP, Scharenberg SG, Camarena J, Kildebeck EJ, Clark JT, Martin RM, Bak RO, Tang Y, Dohse M, Birgmeier JA, Jagadeesh KA, Bejerano G, Tsukamoto A, Gomez-Ospina N, Uchida N, Porteus MH | iScience | 31132746 | iScience | 2019 May 31 | https://www.ncbi.nlm.nih.gov/pubmed/31132746 |
| The RAG2 C terminus suppresses genomic instability and lymphomagenesis. | Deriano L, Chaumeil J, Coussens M, Multani A, Chou Y, Alekseyenko AV, Chang S, Skok JA, Roth DB | Nature | 21368836 | Nature | 2011 Mar 3 | https://www.ncbi.nlm.nih.gov/pubmed/21368836 |
| Translating the lessons from gene therapy to the development of regenerative medicine. | Porteus M | Molecular therapy : the journal of the American Society of Gene Therapy | 21358706 | Mol Ther | 2011 Mar | https://www.ncbi.nlm.nih.gov/pubmed/21358706 |
| Endothelialized microfluidics for studying microvascular interactions in hematologic diseases. | Myers DR, Sakurai Y, Tran R, Ahn B, Hardy ET, Mannino R, Kita A, Tsai M, Lam WA | Journal of visualized experiments : JoVE | 22760254 | J Vis Exp | 2012 Jun 22 | https://www.ncbi.nlm.nih.gov/pubmed/22760254 |
| Nuclear speckles. | Spector DL, Lamond AI | Cold Spring Harbor perspectives in biology | 20926517 | Cold Spring Harb Perspect Biol | 2011 Feb 1 | https://www.ncbi.nlm.nih.gov/pubmed/20926517 |
| Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair. | Hirsch ML, Green L, Porteus MH, Samulski RJ | Gene therapy | 20463753 | Gene Ther | 2010 Sep | https://www.ncbi.nlm.nih.gov/pubmed/20463753 |
| Tat peptide is capable of importing large nanoparticles across nuclear membrane in digitonin permeabilized cells. | Nitin N, LaConte L, Rhee WJ, Bao G | Annals of biomedical engineering | 19657743 | Ann Biomed Eng | 2009 Oct | https://www.ncbi.nlm.nih.gov/pubmed/19657743 |
| NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells. | Nitin N, Bao G | Bioconjugate chemistry | 18939859 | Bioconjug Chem | 2008 Nov 19 | https://www.ncbi.nlm.nih.gov/pubmed/18939859 |
| Genome Editing of the Blood: Opportunities and Challenges. | Porteus MH | Current stem cell reports | 26029496 | Curr Stem Cell Rep | 2015 Mar 1 | https://www.ncbi.nlm.nih.gov/pubmed/26029496 |
| Physical Principles of Nanoparticle Cellular Endocytosis. | Zhang S, Gao H, Bao G | ACS nano | 26256227 | ACS Nano | 2015 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/26256227 |
| Poloxamer surfactant preserves cell viability during photoacoustic delivery of molecules into cells. | Sengupta A, Dwivedi N, Kelly SC, Tucci L, Thadhani NN, Prausnitz MR | Biotechnology and bioengineering | 25182778 | Biotechnol Bioeng | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25182778 |
| Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome. | Müller M, Lee CM, Gasiunas G, Davis TH, Cradick TJ, Siksnys V, Bao G, Cathomen T, Mussolino C | Molecular therapy : the journal of the American Society of Gene Therapy | 26658966 | Mol Ther | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26658966 |
| The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells. | Lee CM, Cradick TJ, Bao G | Molecular therapy : the journal of the American Society of Gene Therapy | 26782639 | Mol Ther | 2016 Mar | https://www.ncbi.nlm.nih.gov/pubmed/26782639 |
| In vivo gene editing in dystrophic mouse muscle and muscle stem cells. | Tabebordbar M, Zhu K, Cheng JKW, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ | Science (New York, N.Y.) | 26721686 | Science | 2016 Jan 22 | https://www.ncbi.nlm.nih.gov/pubmed/26721686 |
| The Role of DNA Mismatch Repair and Recombination in the Processing of DNA Alkylating Damage in Living Yeast Cells. | Flores-Rozas H, Jaafar L, Xia L | Advances in bioscience and biotechnology (Print) | 26900494 | Adv Biosci Biotechnol | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26900494 |
| Design and Validation of CRISPR/Cas9 Systems for Targeted Gene Modification in Induced Pluripotent Stem Cells. | Lee CM, Zhu H, Davis TH, Deshmukh H, Bao G | Methods in molecular biology (Clifton, N.J.) | 27709565 | Methods Mol Biol | 2017 | https://www.ncbi.nlm.nih.gov/pubmed/27709565 |
| Simplified prototyping of perfusable polystyrene microfluidics. | Tran R, Ahn B, Myers DR, Qiu Y, Sakurai Y, Moot R, Mihevc E, Trent Spencer H, Doering C, A Lam W | Biomicrofluidics | 25379106 | Biomicrofluidics | 2014 Jul | https://www.ncbi.nlm.nih.gov/pubmed/25379106 |
| Frontiers in bioengineering research. | Bao G, Nerem RM | Annals of biomedical engineering | 24510229 | Ann Biomed Eng | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/24510229 |
| Nuclease-mediated gene editing by homologous recombination of the human globin locus. | Voit RA, Hendel A, Pruett-Miller SM, Porteus MH | Nucleic acids research | 24157834 | Nucleic Acids Res | 2014 Jan | https://www.ncbi.nlm.nih.gov/pubmed/24157834 |
| Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage. | Deriano L, Roth DB | Annual review of genetics | 24050180 | Annu Rev Genet | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/24050180 |
| Designing and testing the activities of TAL effector nucleases. | Lin Y, Cradick TJ, Bao G | Methods in molecular biology (Clifton, N.J.) | 24557905 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24557905 |
| An unbiased method for detection of genome-wide off-target effects in cell lines treated with zinc finger nucleases. | Lindsay CR, Roth DB | Methods in molecular biology (Clifton, N.J.) | 24557915 | Methods Mol Biol | 2014 | https://www.ncbi.nlm.nih.gov/pubmed/24557915 |
| CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells. | Dever DP, Bak RO, Reinisch A, Camarena J, Washington G, Nicolas CE, Pavel-Dinu M, Saxena N, Wilkens AB, Mantri S, Uchida N, Hendel A, Narla A, Majeti R, Weinberg KI, Porteus MH | Nature | 27820943 | Nature | 2016 Nov 17 | https://www.ncbi.nlm.nih.gov/pubmed/27820943 |
| Modifying the function of DNA repair nanomachines for therapeutic benefit. | Dynan WS, Takeda Y, Li S | Nanomedicine : nanotechnology, biology, and medicine | 17292118 | Nanomedicine | 2006 Jun | https://www.ncbi.nlm.nih.gov/pubmed/17292118 |
| 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. | Dimitrova N, Chen YC, Spector DL, de Lange T | Nature | 18931659 | Nature | 2008 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/18931659 |
| Expanding the substrate tolerance of biotin ligase through exploration of enzymes from diverse species. | Slavoff SA, Chen I, Choi YA, Ting AY | Journal of the American Chemical Society | 18171066 | J Am Chem Soc | 2008 Jan 30 | https://www.ncbi.nlm.nih.gov/pubmed/18171066 |
| Nuclear neighborhoods and gene expression. | Zhao R, Bodnar MS, Spector DL | Current opinion in genetics & development | 19339170 | Curr Opin Genet Dev | 2009 Apr | https://www.ncbi.nlm.nih.gov/pubmed/19339170 |
| Use of a microscope stage-mounted Nickel-63 microirradiator for real-time observation of the DNA double-strand break response. | Cao Z, Kuhne WW, Steeb J, Merkley MA, Zhou Y, Janata J, Dynan WS | Nucleic acids research | 20484377 | Nucleic Acids Res | 2010 Aug | https://www.ncbi.nlm.nih.gov/pubmed/20484377 |
| An unexpected ending: noncanonical 3' end processing mechanisms. | Wilusz JE, Spector DL | RNA (New York, N.Y.) | 20007330 | RNA | 2010 Feb | https://www.ncbi.nlm.nih.gov/pubmed/20007330 |
| Surface ligand effects on metal-affinity coordination to quantum dots: implications for nanoprobe self-assembly. | Dennis AM, Sotto DC, Mei BC, Medintz IL, Mattoussi H, Bao G | Bioconjugate chemistry | 20568725 | Bioconjug Chem | 2010 Jul 21 | https://www.ncbi.nlm.nih.gov/pubmed/20568725 |
| Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation. | Hübner MR, Spector DL | Cold Spring Harbor symposia on quantitative biology | 21209387 | Cold Spring Harb Symp Quant Biol | 2010 | https://www.ncbi.nlm.nih.gov/pubmed/21209387 |
| A streamlined method for detecting structural variants in cancer genomes by short read paired-end sequencing. | Mijušković M, Brown SM, Tang Z, Lindsay CR, Efstathiadis E, Deriano L, Roth DB | PloS one | 23144753 | PLoS One | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/23144753 |
| Compact quantum dots for single-molecule imaging. | Smith AM, Nie S | Journal of visualized experiments : JoVE | 23093375 | J Vis Exp | 2012 Oct 9 | https://www.ncbi.nlm.nih.gov/pubmed/23093375 |
| Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs. | Ellis BL, Hirsch ML, Porter SN, Samulski RJ, Porteus MH | Gene therapy | 22257934 | Gene Ther | 2013 Jan | https://www.ncbi.nlm.nih.gov/pubmed/22257934 |
| Biogenesis and function of nuclear bodies. | Mao YS, Zhang B, Spector DL | Trends in genetics : TIG | 21680045 | Trends Genet | 2011 Aug | https://www.ncbi.nlm.nih.gov/pubmed/21680045 |
| Self-assembly of phospholipid-PEG coating on nanoparticles through dual solvent exchange. | Tong S, Hou S, Ren B, Zheng Z, Bao G | Nano letters | 21793503 | Nano Lett | 2011 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/21793503 |
| Single-cell detection of mRNA expression using nanofountain-probe electroporated molecular beacons. | Giraldo-Vela JP, Kang W, McNaughton RL, Zhang X, Wile BM, Tsourkas A, Bao G, Espinosa HD | Small (Weinheim an der Bergstrasse, Germany) | 25641752 | Small | 2015 May | https://www.ncbi.nlm.nih.gov/pubmed/25641752 |
| Quantifying on- and off-target genome editing. | Hendel A, Fine EJ, Bao G, Porteus MH | Trends in biotechnology | 25595557 | Trends Biotechnol | 2015 Feb | https://www.ncbi.nlm.nih.gov/pubmed/25595557 |
| Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles. | Sengupta A, Mezencev R, McDonald JF, Prausnitz MR | Nanomedicine (London, England) | 26080699 | Nanomedicine (Lond) | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/26080699 |
| Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus. | Mijušković M, Chou YF, Gigi V, Lindsay CR, Shestova O, Lewis SM, Roth DB | Cell reports | 26365182 | Cell Rep | 2015 Sep 22 | https://www.ncbi.nlm.nih.gov/pubmed/26365182 |
| Towards a new era in medicine: therapeutic genome editing. | Porteus MH | Genome biology | 26694713 | Genome Biol | 2015 Dec 22 | https://www.ncbi.nlm.nih.gov/pubmed/26694713 |
| CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences. | Lin Y, Cradick TJ, Brown MT, Deshmukh H, Ranjan P, Sarode N, Wile BM, Vertino PM, Stewart FJ, Bao G | Nucleic acids research | 24838573 | Nucleic Acids Res | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24838573 |
| SAPTA: a new design tool for improving TALE nuclease activity. | Lin Y, Fine EJ, Zheng Z, Antico CJ, Voit RA, Porteus MH, Cradick TJ, Bao G | Nucleic acids research | 24442582 | Nucleic Acids Res | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24442582 |
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| Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons. | Peled ES, Isacoff EY | Nature neuroscience | 21378971 | Nat Neurosci | 2011 Apr | https://www.ncbi.nlm.nih.gov/pubmed/21378971 |
| Optical control of calcium affinity in a spiroamido-rhodamine based calcium chelator. | Wu L, Dai Y, Marriott G | Organic letters | 21417245 | Org Lett | 2011 Apr 15 | https://www.ncbi.nlm.nih.gov/pubmed/21417245 |
| A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. | Janovjak H, Szobota S, Wyart C, Trauner D, Isacoff EY | Nature neuroscience | 20581843 | Nat Neurosci | 2010 Aug | https://www.ncbi.nlm.nih.gov/pubmed/20581843 |
| New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo. | Rush JS, Bertozzi CR | Journal of the American Chemical Society | 18722427 | J Am Chem Soc | 2008 Sep 17 | https://www.ncbi.nlm.nih.gov/pubmed/18722427 |
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| Omnidirectional 3D nanoplasmonic optical antenna array via soft-matter transformation. | Ross BM, Wu LY, Lee LP | Nano letters | 21661733 | Nano Lett | 2011 Jul 13 | https://www.ncbi.nlm.nih.gov/pubmed/21661733 |
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| Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h-/- mouse. | Byrne LC, Oztürk BE, Lee T, Fortuny C, Visel M, Dalkara D, Schaffer DV, Flannery JG | Gene therapy | 24694538 | Gene Ther | 2014 Jun | https://www.ncbi.nlm.nih.gov/pubmed/24694538 |
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| High-contrast fluorescence imaging in fixed and living cells using optimized optical switches. | Wu L, Dai Y, Jiang X, Petchprayoon C, Lee JE, Jiang T, Yan Y, Marriott G | PloS one | 23755140 | PLoS One | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23755140 |
| A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor. | Kienzler MA, Reiner A, Trautman E, Yoo S, Trauner D, Isacoff EY | Journal of the American Chemical Society | 24171511 | J Am Chem Soc | 2013 Nov 27 | https://www.ncbi.nlm.nih.gov/pubmed/24171511 |
| Light at the end of the channel: optical manipulation of intrinsic neuronal excitability with chemical photoswitches. | Mourot A, Tochitsky I, Kramer RH | Frontiers in molecular neuroscience | 23518818 | Front Mol Neurosci | 2013 | https://www.ncbi.nlm.nih.gov/pubmed/23518818 |
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| Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa. | Marsili S, Genini S, Sudharsan R, Gingrich J, Aguirre GD, Beltran WA | PloS one | 25695253 | PLoS One | 2015 | https://www.ncbi.nlm.nih.gov/pubmed/25695253 |
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| Restoration of high-sensitivity and adapting vision with a cone opsin. | Berry MH, Holt A, Salari A, Veit J, Visel M, Levitz J, Aghi K, Gaub BM, Sivyer B, Flannery JG, Isacoff EY | Nature communications | 30874546 | Nat Commun | 2019 Mar 15 | https://www.ncbi.nlm.nih.gov/pubmed/30874546 |
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| High throughput cell nanomechanics with mechanical imaging interferometry. | Reed J, Frank M, Troke JJ, Schmit J, Han S, Teitell MA, Gimzewski JK | Nanotechnology | 20737027 | Nanotechnology | 2008 Jun 11 | https://www.ncbi.nlm.nih.gov/pubmed/20737027 |
| High-speed droplet generation on demand driven by pulse laser-induced cavitation. | Park SY, Wu TH, Chen Y, Teitell MA, Chiou PY | Lab on a chip | 21290045 | Lab Chip | 2011 Mar 21 | https://www.ncbi.nlm.nih.gov/pubmed/21290045 |
| A noninvasive, motility independent, sperm sorting method and technology to identify and retrieve individual viable nonmotile sperm for intracytoplasmic sperm injection. | Garcia MM, Ohta AT, Walsh TJ, Vittinghof E, Lin G, Wu MC, Lue TF | The Journal of urology | 20952004 | J Urol | 2010 Dec | https://www.ncbi.nlm.nih.gov/pubmed/20952004 |
| Cell Separation by Non-Inertial Force Fields in Microfluidic Systems. | Tsutsui H, Ho CM | Mechanics research communications | 20046897 | Mech Res Commun | 2009 Jan 1 | https://www.ncbi.nlm.nih.gov/pubmed/20046897 |
| Parallel trapping of multiwalled carbon nanotubes with optoelectronic tweezers. | Pauzauskie PJ, Jamshidi A, Valley JK, Satcher JH, Wu MC | Applied physics letters | 19884988 | Appl Phys Lett | 2009 Sep 14 | https://www.ncbi.nlm.nih.gov/pubmed/19884988 |
| Preimplantation mouse embryo selection guided by light-induced dielectrophoresis. | Valley JK, Swinton P, Boscardin WJ, Lue TF, Rinaudo PF, Wu MC, Garcia MM | PloS one | 20405021 | PLoS One | 2010 Apr 13 | https://www.ncbi.nlm.nih.gov/pubmed/20405021 |
| Image patterned molecular delivery into live cells using gold particle coated substrates. | Wu TH, Kalim S, Callahan C, Teitell MA, Chiou PY | Optics express | 20173916 | Opt Express | 2010 Jan 18 | https://www.ncbi.nlm.nih.gov/pubmed/20173916 |
| Dynamic manipulation and separation of individual semiconducting and metallic nanowires. | Jamshidi A, Pauzauskie PJ, Schuck PJ, Ohta AT, Chiou PY, Chou J, Yang P, Wu MC | Nature photonics | 19789729 | Nat Photonics | 2008 | https://www.ncbi.nlm.nih.gov/pubmed/19789729 |
| Self-amplifying autocrine actions of BDNF in axon development. | Cheng PL, Song AH, Wong YH, Wang S, Zhang X, Poo MM | Proceedings of the National Academy of Sciences of the United States of America | 22025720 | Proc Natl Acad Sci U S A | 2011 Nov 8 | https://www.ncbi.nlm.nih.gov/pubmed/22025720 |
| Systematic quantitative characterization of cellular responses induced by multiple signals. | Al-Shyoukh I, Yu F, Feng J, Yan K, Dubinett S, Ho CM, Shamma JS, Sun R | BMC systems biology | 21624115 | BMC Syst Biol | 2011 May 30 | https://www.ncbi.nlm.nih.gov/pubmed/21624115 |
| Rapidly quantifying drug sensitivity of dispersed and clumped breast cancer cells by mass profiling. | Chun J, Zangle TA, Kolarova T, Finn RS, Teitell MA, Reed J | The Analyst | 23057068 | Analyst | 2012 Dec 7 | https://www.ncbi.nlm.nih.gov/pubmed/23057068 |
| Cascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity. | Ding X, Sanchez DJ, Shahangian A, Al-Shyoukh I, Cheng G, Ho CM | International journal of nanomedicine | 22654513 | Int J Nanomedicine | 2012 | https://www.ncbi.nlm.nih.gov/pubmed/22654513 |
| Rapidly optimizing an aptamer based BoNT sensor by feedback system control (FSC) scheme. | Wei F, Bai B, Ho CM | Biosensors & bioelectronics | 21993141 | Biosens Bioelectron | 2011 Dec 15 | https://www.ncbi.nlm.nih.gov/pubmed/21993141 |
| Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade. | French CT, Toesca IJ, Wu TH, Teslaa T, Beaty SM, Wong W, Liu M, Schröder I, Chiou PY, Teitell MA, Miller JF | Proceedings of the National Academy of Sciences of the United States of America | 21730143 | Proc Natl Acad Sci U S A | 2011 Jul 19 | https://www.ncbi.nlm.nih.gov/pubmed/21730143 |
| Coffee ring aptasensor for rapid protein detection. | Wen JT, Ho CM, Lillehoj PB | Langmuir : the ACS journal of surfaces and colloids | 23540796 | Langmuir | 2013 Jul 2 | https://www.ncbi.nlm.nih.gov/pubmed/23540796 |
| Developing defined culture systems for human pluripotent stem cells. | Valamehr B, Tsutsui H, Ho CM, Wu H | Regenerative medicine | 21916597 | Regen Med | 2011 Sep | https://www.ncbi.nlm.nih.gov/pubmed/21916597 |
| Rapid, massively parallel single-cell drug response measurements via live cell interferometry. | Reed J, Chun J, Zangle TA, Kalim S, Hong JS, Pefley SE, Zheng X, Gimzewski JK, Teitell MA | Biophysical journal | 21889438 | Biophys J | 2011 Sep 7 | https://www.ncbi.nlm.nih.gov/pubmed/21889438 |
| Intracellular delivery of top-down fabricated tunable nano-plasmonic resonators. | Ota S, Wang S, Ryu J, Wang Y, Chen Y, Zhang X | Nanoscale | 24056760 | Nanoscale | 2013 Nov 7 | https://www.ncbi.nlm.nih.gov/pubmed/24056760 |
| Electrical impedance monitoring of photothermal porated mammalian cells. | Yamane D, Wu YC, Wu TH, Toshiyoshi H, Teitell MA, Chiou PY | Journal of laboratory automation | 23797097 | J Lab Autom | 2014 Feb | https://www.ncbi.nlm.nih.gov/pubmed/23797097 |
| Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. | Bendall SC, Davis KL, Amir el-AD, Tadmor MD, Simonds EF, Chen TJ, Shenfeld DK, Nolan GP, Pe'er D | Cell | 24766814 | Cell | 2014 Apr 24 | https://www.ncbi.nlm.nih.gov/pubmed/24766814 |
| Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκB. | Teh BE, French CT, Chen Y, Chen IG, Wu TH, Sagullo E, Chiou PY, Teitell MA, Miller JF, Gan YH | BMC microbiology | 24884837 | BMC Microbiol | 2014 May 6 | https://www.ncbi.nlm.nih.gov/pubmed/24884837 |
| Use of cell morphology as early bioindicator for viral infection. | Ding X, Liu N, Matsuo K, Sun M, Zhao X | IET nanobiotechnology | 24888188 | IET Nanobiotechnol | 2014 Mar | https://www.ncbi.nlm.nih.gov/pubmed/24888188 |
| Multiplexed ion beam imaging of human breast tumors. | Angelo M, Bendall SC, Finck R, Hale MB, Hitzman C, Borowsky AD, Levenson RM, Lowe JB, Liu SD, Zhao S, Natkunam Y, Nolan GP | Nature medicine | 24584119 | Nat Med | 2014 Apr | https://www.ncbi.nlm.nih.gov/pubmed/24584119 |
| Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus. | Sen N, Mukherjee G, Sen A, Bendall SC, Sung P, Nolan GP, Arvin AM | Cell reports | 25043183 | Cell Rep | 2014 Jul 24 | https://www.ncbi.nlm.nih.gov/pubmed/25043183 |
