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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
| Title | Author | Journal Name | PubMedID | Journal Abbreviation | Publication Date |
|---|---|---|---|---|---|
| A multifunctional AAV-CRISPR-Cas9 and its host response. | Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM | Nature methods | 27595405 | Nat Methods | 2016 Oct |
| CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences. | Lin Y, Cradick TJ, Brown MT, Deshmukh H, Ranjan P, Sarode N, Wile BM, Vertino PM, Stewart FJ, Bao G | Nucleic acids research | 24838573 | Nucleic Acids Res | 2014 Jun |
| CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells. | Dever DP, Bak RO, Reinisch A, Camarena J, Washington G, Nicolas CE, Pavel-Dinu M, Saxena N, Wilkens AB, Mantri S, Uchida N, Hendel A, Narla A, Majeti R, Weinberg KI, Porteus MH | Nature | 27820943 | Nature | 2016 Nov 17 |
| Treating hemoglobinopathies using gene-correction approaches: promises and challenges. | Cottle RN, Lee CM, Bao G | Human genetics | 27314256 | Hum Genet | 2016 Sep |
| Self-assembly of phospholipid-PEG coating on nanoparticles through dual solvent exchange. | Tong S, Hou S, Ren B, Zheng Z, Bao G | Nano letters | 21793503 | Nano Lett | 2011 Sep 14 |
| A streamlined method for detecting structural variants in cancer genomes by short read paired-end sequencing. | Mijušković M, Brown SM, Tang Z, Lindsay CR, Efstathiadis E, Deriano L, Roth DB | PloS one | 23144753 | PLoS One | 2012 |
| Imaging dynamic cellular events with quantum dots The bright future. | Smith AM, Wen MM, Nie S | The biochemist | 20824157 | Biochem (Lond) | 2010 Jun 1 |
| Nonrigid registration of 2-D and 3-D dynamic cell nuclei images for improved classification of subcellular particle motion. | Kim IH, Chen YC, Spector DL, Eils R, Rohr K | IEEE transactions on image processing : a publication of the IEEE Signal Processing Society | 20840894 | IEEE Trans Image Process | 2011 Apr |
| Biogenesis and function of nuclear bodies. | Mao YS, Zhang B, Spector DL | Trends in genetics : TIG | 21680045 | Trends Genet | 2011 Aug |
| Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications. | Li S, Nguyen L, Xiong H, Wang M, Hu TC, She JX, Serkiz SM, Wicks GG, Dynan WS | Nanomedicine : nanotechnology, biology, and medicine | 19616128 | Nanomedicine | 2010 Feb |
| Protein Mechanics: A New Frontier in Biomechanics. | Bao G | Experimental mechanics | 19809588 | Exp Mech | 2009 Feb 1 |
| Tuning the optical and electronic properties of colloidal nanocrystals by lattice strain. | Smith AM, Mohs AM, Nie S | Nature nanotechnology | 19119284 | Nat Nanotechnol | 2009 Jan |
| Poloxamer surfactant preserves cell viability during photoacoustic delivery of molecules into cells. | Sengupta A, Dwivedi N, Kelly SC, Tucci L, Thadhani NN, Prausnitz MR | Biotechnology and bioengineering | 25182778 | Biotechnol Bioeng | 2015 Feb |
| Intranuclear delivery of a novel antibody-derived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit. | Xiong H, Lee RJ, Haura EB, Edwards JG, Dynan WS, Li S | International journal of radiation oncology, biology, physics | 22138455 | Int J Radiat Oncol Biol Phys | 2012 Jul 1 |
| The RAG2 C terminus suppresses genomic instability and lymphomagenesis. | Deriano L, Chaumeil J, Coussens M, Multani A, Chou Y, Alekseyenko AV, Chang S, Skok JA, Roth DB | Nature | 21368836 | Nature | 2011 Mar 3 |
| DNA targeting specificity of RNA-guided Cas9 nucleases. | Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F | Nature biotechnology | 23873081 | Nat Biotechnol | 2013 Sep |
| Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage. | Deriano L, Roth DB | Annual review of genetics | 24050180 | Annu Rev Genet | 2013 |
| Understanding and re-engineering nucleoprotein machines to cure human disease. | Dynan W, Takeda Y, Roth D, Bao G | Nanomedicine (London, England) | 18393669 | Nanomedicine (Lond) | 2008 Feb |
| Nuclear neighborhoods and gene expression. | Zhao R, Bodnar MS, Spector DL | Current opinion in genetics & development | 19339170 | Curr Opin Genet Dev | 2009 Apr |
| Nanomedicine: tiny particles and machines give huge gains. | Tong S, Fine EJ, Lin Y, Cradick TJ, Bao G | Annals of biomedical engineering | 24297494 | Ann Biomed Eng | 2014 Feb |
| The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells. | Lee CM, Cradick TJ, Bao G | Molecular therapy : the journal of the American Society of Gene Therapy | 26782639 | Mol Ther | 2016 Mar |
| Chromatin dynamics. | Hübner MR, Spector DL | Annual review of biophysics | 20462379 | Annu Rev Biophys | 2010 |
| Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair. | Hirsch ML, Green L, Porteus MH, Samulski RJ | Gene therapy | 20463753 | Gene Ther | 2010 Sep |
| Use of a microscope stage-mounted Nickel-63 microirradiator for real-time observation of the DNA double-strand break response. | Cao Z, Kuhne WW, Steeb J, Merkley MA, Zhou Y, Janata J, Dynan WS | Nucleic acids research | 20484377 | Nucleic Acids Res | 2010 Aug |
| Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice. | Meiler SE, Wade M, Kutlar F, Yerigenahally SD, Xue Y, Moutouh-de Parseval LA, Corral LG, Swerdlow PS, Kutlar A | Blood | 21536862 | Blood | 2011 Jul 28 |
| NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells. | Nitin N, Bao G | Bioconjugate chemistry | 18939859 | Bioconjug Chem | 2008 Nov 19 |
| An unexpected ending: noncanonical 3' end processing mechanisms. | Wilusz JE, Spector DL | RNA (New York, N.Y.) | 20007330 | RNA | 2010 Feb |
| Bioimaging: second window for in vivo imaging. | Smith AM, Mancini MC, Nie S | Nature nanotechnology | 19898521 | Nat Nanotechnol | 2009 Nov |
| Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs. | Ellis BL, Hirsch ML, Porter SN, Samulski RJ, Porteus MH | Gene therapy | 22257934 | Gene Ther | 2013 Jan |
| Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus. | Mijušković M, Chou YF, Gigi V, Lindsay CR, Shestova O, Lewis SM, Roth DB | Cell reports | 26365182 | Cell Rep | 2015 Sep 22 |
| Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing. | Hendel A, Kildebeck EJ, Fine EJ, Clark J, Punjya N, Sebastiano V, Bao G, Porteus MH | Cell reports | 24685129 | Cell Rep | 2014 Apr 10 |
| Single-cell detection of mRNA expression using nanofountain-probe electroporated molecular beacons. | Giraldo-Vela JP, Kang W, McNaughton RL, Zhang X, Wile BM, Tsourkas A, Bao G, Espinosa HD | Small (Weinheim an der Bergstrasse, Germany) | 25641752 | Small | 2015 May |
| Quantifying on- and off-target genome editing. | Hendel A, Fine EJ, Bao G, Porteus MH | Trends in biotechnology | 25595557 | Trends Biotechnol | 2015 Feb |
| An unbiased method for detection of genome-wide off-target effects in cell lines treated with zinc finger nucleases. | Lindsay CR, Roth DB | Methods in molecular biology (Clifton, N.J.) | 24557915 | Methods Mol Biol | 2014 |
| SAPTA: a new design tool for improving TALE nuclease activity. | Lin Y, Fine EJ, Zheng Z, Antico CJ, Voit RA, Porteus MH, Cradick TJ, Bao G | Nucleic acids research | 24442582 | Nucleic Acids Res | 2014 Apr |
| Receptor-mediated delivery of engineered nucleases for genome modification. | Chen Z, Jaafar L, Agyekum DG, Xiao H, Wade MF, Kumaran RI, Spector DL, Bao G, Porteus MH, Dynan WS, Meiler SE | Nucleic acids research | 23956220 | Nucleic Acids Res | 2013 Oct |
| Nuclease-mediated gene editing by homologous recombination of the human globin locus. | Voit RA, Hendel A, Pruett-Miller SM, Porteus MH | Nucleic acids research | 24157834 | Nucleic Acids Res | 2014 Jan |
| Designing and testing the activities of TAL effector nucleases. | Lin Y, Cradick TJ, Bao G | Methods in molecular biology (Clifton, N.J.) | 24557905 | Methods Mol Biol | 2014 |
| Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models. | Fine EJ, Cradick TJ, Bao G | Methods in molecular biology (Clifton, N.J.) | 24557916 | Methods Mol Biol | 2014 |
| In vivo gene editing in dystrophic mouse muscle and muscle stem cells. | Tabebordbar M, Zhu K, Cheng JKW, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ | Science (New York, N.Y.) | 26721686 | Science | 2016 Jan 22 |
| Towards a new era in medicine: therapeutic genome editing. | Porteus MH | Genome biology | 26694713 | Genome Biol | 2015 Dec 22 |
| Intracellular delivery of molecules using microfabricated nanoneedle arrays. | Park S, Choi SO, Paik SJ, Choi S, Allen M, Prausnitz M | Biomedical microdevices | 26797026 | Biomed Microdevices | 2016 Feb |
| Spatial control of in vivo CRISPR-Cas9 genome editing via nanomagnets. | Zhu H, Zhang L, Tong S, Lee CM, Deshmukh H, Bao G | Nature biomedical engineering | 30944431 | Nat Biomed Eng | 2019 Feb |
| Genome Editing: A New Approach to Human Therapeutics. | Porteus M | Annual review of pharmacology and toxicology | 26566154 | Annu Rev Pharmacol Toxicol | 2016 |
| Quantum dot-fluorescent protein FRET probes for sensing intracellular pH. | Dennis AM, Rhee WJ, Sotto D, Dublin SN, Bao G | ACS nano | 22443420 | ACS Nano | 2012 Apr 24 |
| Chromatin meets its organizers. | Bodnar MS, Spector DL | Cell | 23746835 | Cell | 2013 Jun 6 |
| E. coli expression of a soluble, active single-chain antibody variable fragment containing a nuclear localization signal. | Xiong H, Li S, Yang Z, Burgess RR, Dynan WS | Protein expression and purification | 19281848 | Protein Expr Purif | 2009 Aug |
| NANOSTRUCTURED PROBES FOR IN VIVO GENE DETECTION. | Bao G, Santangelo P, Nitin N, Rhee WJ | Nanomedicine : design and applications of magnetic nanomaterials, nanosensors, and nanosystems | 22138717 | Nanomedicine (Chichester) | 2010 |
| Modifying the function of DNA repair nanomachines for therapeutic benefit. | Dynan WS, Takeda Y, Li S | Nanomedicine : nanotechnology, biology, and medicine | 17292118 | Nanomedicine | 2006 Jun |
| 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. | Dimitrova N, Chen YC, Spector DL, de Lange T | Nature | 18931659 | Nature | 2008 Nov 27 |
| Imaging and tracking of tat peptide-conjugated quantum dots in living cells: new insights into nanoparticle uptake, intracellular transport, and vesicle shedding. | Ruan G, Agrawal A, Marcus AI, Nie S | Journal of the American Chemical Society | 17983227 | J Am Chem Soc | 2007 Nov 28 |
| TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity. | Mussolino C, Alzubi J, Fine EJ, Morbitzer R, Cradick TJ, Lahaye T, Bao G, Cathomen T | Nucleic acids research | 24792154 | Nucleic Acids Res | 2014 Jun |
| Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease. | Connelly JP, Barker JC, Pruett-Miller S, Porteus MH | Molecular therapy : the journal of the American Society of Gene Therapy | 20389291 | Mol Ther | 2010 Jun |
| Translating the lessons from gene therapy to the development of regenerative medicine. | Porteus M | Molecular therapy : the journal of the American Society of Gene Therapy | 21358706 | Mol Ther | 2011 Mar |
| Semiconductor nanocrystals: structure, properties, and band gap engineering. | Smith AM, Nie S | Accounts of chemical research | 19827808 | Acc Chem Res | 2010 Feb 16 |
| An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage. | Fine EJ, Cradick TJ, Zhao CL, Lin Y, Bao G | Nucleic acids research | 24381193 | Nucleic Acids Res | 2014 Apr |
| Endothelialized microfluidics for studying microvascular interactions in hematologic diseases. | Myers DR, Sakurai Y, Tran R, Ahn B, Hardy ET, Mannino R, Kita A, Tsai M, Lam WA | Journal of visualized experiments : JoVE | 22760254 | J Vis Exp | 2012 Jun 22 |
| COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites. | Cradick TJ, Qiu P, Lee CM, Fine EJ, Bao G | Molecular therapy. Nucleic acids | 25462530 | Mol Ther Nucleic Acids | 2014 Dec 2 |
| Physical Principles of Nanoparticle Cellular Endocytosis. | Zhang S, Gao H, Bao G | ACS nano | 26256227 | ACS Nano | 2015 Sep 22 |
| TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs. | Suzuki S, Sargent RG, Illek B, Fischer H, Esmaeili-Shandiz A, Yezzi MJ, Lee A, Yang Y, Kim S, Renz P, Qi Z, Yu J, Muench MO, Beyer AI, Guimarães AO, Ye L, Chang J, Fine EJ, Cradick TJ, Bao G, Rahdar M, Porteus MH, Shuto T, Kai H, Kan YW, Gruenert DC | Molecular therapy. Nucleic acids | 26730810 | Mol Ther Nucleic Acids | 2016 Jan 5 |
| Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6. | Bak RO, Dever DP, Reinisch A, Cruz Hernandez D, Majeti R, Porteus MH | eLife | 28956530 | Elife | 2017 Sep 28 |
| The Role of DNA Mismatch Repair and Recombination in the Processing of DNA Alkylating Damage in Living Yeast Cells. | Flores-Rozas H, Jaafar L, Xia L | Advances in bioscience and biotechnology (Print) | 26900494 | Adv Biosci Biotechnol | 2015 |
| Genome Editing of the Blood: Opportunities and Challenges. | Porteus MH | Current stem cell reports | 26029496 | Curr Stem Cell Rep | 2015 Mar 1 |
| Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles. | Sengupta A, Mezencev R, McDonald JF, Prausnitz MR | Nanomedicine (London, England) | 26080699 | Nanomedicine (Lond) | 2015 |
| Simplified prototyping of perfusable polystyrene microfluidics. | Tran R, Ahn B, Myers DR, Qiu Y, Sakurai Y, Moot R, Mihevc E, Trent Spencer H, Doering C, A Lam W | Biomicrofluidics | 25379106 | Biomicrofluidics | 2014 Jul |
| Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector. | Abarrategui-Pontes C, Créneguy A, Thinard R, Fine EJ, Thepenier V, Fournier le RL, Cradick TJ, Bao G, Tesson L, Podevin G, Anegon I, Nguyen TH | Current gene therapy | 25687502 | Curr Gene Ther | 2014 |
| Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells. | Hendel A, Bak RO, Clark JT, Kennedy AB, Ryan DE, Roy S, Steinfeld I, Lunstad BD, Kaiser RJ, Wilkens AB, Bacchetta R, Tsalenko A, Dellinger D, Bruhn L, Porteus MH | Nature biotechnology | 26121415 | Nat Biotechnol | 2015 Sep |
| Chromatin dynamics and gene positioning. | Kumaran RI, Thakar R, Spector DL | Cell | 18358806 | Cell | 2008 Mar 21 |
| Bioconjugated quantum dots for in vivo molecular and cellular imaging. | Smith AM, Duan H, Mohs AM, Nie S | Advanced drug delivery reviews | 18495291 | Adv Drug Deliv Rev | 2008 Aug 17 |
| Expanding the substrate tolerance of biotin ligase through exploration of enzymes from diverse species. | Slavoff SA, Chen I, Choi YA, Ting AY | Journal of the American Chemical Society | 18171066 | J Am Chem Soc | 2008 Jan 30 |
| Bright and compact alloyed quantum dots with broadly tunable near-infrared absorption and fluorescence spectra through mercury cation exchange. | Smith AM, Nie S | Journal of the American Chemical Society | 21142154 | J Am Chem Soc | 2011 Jan 12 |
| Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells. | Ha K, Takeda Y, Dynan WS | DNA repair | 21144806 | DNA Repair (Amst) | 2011 Mar 7 |
| Nuclear speckles. | Spector DL, Lamond AI | Cold Spring Harbor perspectives in biology | 20926517 | Cold Spring Harb Perspect Biol | 2011 Feb 1 |
| Surface ligand effects on metal-affinity coordination to quantum dots: implications for nanoprobe self-assembly. | Dennis AM, Sotto DC, Mei BC, Medintz IL, Mattoussi H, Bao G | Bioconjugate chemistry | 20568725 | Bioconjug Chem | 2010 Jul 21 |
| Tat peptide is capable of importing large nanoparticles across nuclear membrane in digitonin permeabilized cells. | Nitin N, LaConte L, Rhee WJ, Bao G | Annals of biomedical engineering | 19657743 | Ann Biomed Eng | 2009 Oct |
| Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation. | Hübner MR, Spector DL | Cold Spring Harbor symposia on quantitative biology | 21209387 | Cold Spring Harb Symp Quant Biol | 2010 |
| Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation. | Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino RG, Tran R, Ahn B, Hardy ET, Kee MF, Kumar S, Bao G, Barker TH, Lam WA | Proceedings of the National Academy of Sciences of the United States of America | 25246564 | Proc Natl Acad Sci U S A | 2014 Oct 7 |
| Multifunctional nanoparticles for drug delivery and molecular imaging. | Bao G, Mitragotri S, Tong S | Annual review of biomedical engineering | 23642243 | Annu Rev Biomed Eng | 2013 |
| Drug delivery: Puncturing cells en masse. | Prausnitz MR | Nature materials | 25899907 | Nat Mater | 2015 May |
| Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis. | Rowe RG, Wang LD, Coma S, Han A, Mathieu R, Pearson DS, Ross S, Sousa P, Nguyen PT, Rodriguez A, Wagers AJ, Daley GQ | The Journal of experimental medicine | 27401346 | J Exp Med | 2016 Jul 25 |
| Design and Validation of CRISPR/Cas9 Systems for Targeted Gene Modification in Induced Pluripotent Stem Cells. | Lee CM, Zhu H, Davis TH, Deshmukh H, Bao G | Methods in molecular biology (Clifton, N.J.) | 27709565 | Methods Mol Biol | 2017 |
| Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection. | Cottle RN, Lee CM, Archer D, Bao G | Scientific reports | 26558999 | Sci Rep | 2015 Nov 12 |
| CRISPR/Cas9 Genome Engineering in Engraftable Human Brain-Derived Neural Stem Cells. | Dever DP, Scharenberg SG, Camarena J, Kildebeck EJ, Clark JT, Martin RM, Bak RO, Tang Y, Dohse M, Birgmeier JA, Jagadeesh KA, Bejerano G, Tsukamoto A, Gomez-Ospina N, Uchida N, Porteus MH | iScience | 31132746 | iScience | 2019 May 31 |
| Compact quantum dots for single-molecule imaging. | Smith AM, Nie S | Journal of visualized experiments : JoVE | 23093375 | J Vis Exp | 2012 Oct 9 |
| Engineering imaging probes and molecular machines for nanomedicine. | Tong S, Cradick TJ, Ma Y, Dai Z, Bao G | Science China. Life sciences | 23108862 | Sci China Life Sci | 2012 Oct |
| CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity. | Cradick TJ, Fine EJ, Antico CJ, Bao G | Nucleic acids research | 23939622 | Nucleic Acids Res | 2013 Nov |
| Frontiers in bioengineering research. | Bao G, Nerem RM | Annals of biomedical engineering | 24510229 | Ann Biomed Eng | 2014 Feb |
| Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome. | Müller M, Lee CM, Gasiunas G, Davis TH, Cradick TJ, Siksnys V, Bao G, Cathomen T, Mussolino C | Molecular therapy : the journal of the American Society of Gene Therapy | 26658966 | Mol Ther | 2016 Mar |
| Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease. | Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin JF, Bao G, Lagor WR | Scientific reports | 28300165 | Sci Rep | 2017 Mar 16 |
| Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase. | Puthenveetil S, Liu DS, White KA, Thompson S, Ting AY | Journal of the American Chemical Society | 19863063 | J Am Chem Soc | 2009 Nov 18 |
| Long noncoding RNAs: functional surprises from the RNA world. | Wilusz JE, Sunwoo H, Spector DL | Genes & development | 19571179 | Genes Dev | 2009 Jul 1 |
| Next-generation quantum dots. | Smith AM, Nie S | Nature biotechnology | 19668181 | Nat Biotechnol | 2009 Aug |
| Homologous recombination-based gene therapy for the primary immunodeficiencies. | Porteus M | Annals of the New York Academy of Sciences | 22236437 | Ann N Y Acad Sci | 2011 Dec |
| In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology. | Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, Ware RE, Fletcher DA, Lam WA | The Journal of clinical investigation | 22156199 | J Clin Invest | 2012 Jan |
| Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level. | Kita A, Sakurai Y, Myers DR, Rounsevell R, Huang JN, Seok TJ, Yu K, Wu MC, Fletcher DA, Lam WA | PloS one | 22028878 | PLoS One | 2011 |
| Examination of CRISPR/Cas9 design tools and the effect of target site accessibility on Cas9 activity. | Lee CM, Davis TH, Bao G | Experimental physiology | 28303677 | Exp Physiol | 2018 Apr 1 |
| Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors. | Rao TN, Gupta MK, Softic S, Wang LD, Jang YC, Thomou T, Bezy O, Kulkarni RN, Kahn CR, Wagers AJ | The EMBO journal | 30446598 | EMBO J | 2018 Dec 14 |
| Different mechanisms regulate productive herpes simplex virus 1 (HSV-1) and HSV-2 infections in adult trigeminal neurons. | Bertke AS, Ma A, Margolis MS, Margolis TP | Journal of virology | 23514893 | J Virol | 2013 Jun |
| Assessment of visual function and retinal structure following acute light exposure in the light sensitive T4R rhodopsin mutant dog. | Iwabe S, Ying GS, Aguirre GD, Beltran WA | Experimental eye research | 27085210 | Exp Eye Res | 2016 May |
| Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h-/- mouse. | Byrne LC, Oztürk BE, Lee T, Fortuny C, Visel M, Dalkara D, Schaffer DV, Flannery JG | Gene therapy | 24694538 | Gene Ther | 2014 Jun |
| How Azobenzene Photoswitches Restore Visual Responses to the Blind Retina. | Tochitsky I, Helft Z, Meseguer V, Fletcher RB, Vessey KA, Telias M, Denlinger B, Malis J, Fletcher EL, Kramer RH | Neuron | 27667006 | Neuron | 2016 Oct 5 |
| Optical properties of the crescent-shaped nanohole antenna. | Wu LY, Ross BM, Lee LP | Nano letters | 19354226 | Nano Lett | 2009 May |
| Tuning photochromic ion channel blockers. | Mourot A, Kienzler MA, Banghart MR, Fehrentz T, Huber FM, Stein M, Kramer RH, Trauner D | ACS chemical neuroscience | 22860175 | ACS Chem Neurosci | 2011 Sep 21 |
| Activation of specific interneurons improves V1 feature selectivity and visual perception. | Lee SH, Kwan AC, Zhang S, Phoumthipphavong V, Flannery JG, Masmanidis SC, Taniguchi H, Huang ZJ, Zhang F, Boyden ES, Deisseroth K, Dan Y | Nature | 22878719 | Nature | 2012 Aug 16 |
| Intravitreal injection of AAV2 transduces macaque inner retina. | Yin L, Greenberg K, Hunter JJ, Dalkara D, Kolstad KD, Masella BD, Wolfe R, Visel M, Stone D, Libby RT, Diloreto D Jr, Schaffer D, Flannery J, Williams DR, Merigan WH | Investigative ophthalmology & visual science | 21310920 | Invest Ophthalmol Vis Sci | 2011 Apr 25 |
| A modern ionotropic glutamate receptor with a K(+) selectivity signature sequence. | Janovjak H, Sandoz G, Isacoff EY | Nature communications | 21407198 | Nat Commun | 2011 |
| Pseudomonas aeruginosa Homoserine lactone activates store-operated cAMP and cystic fibrosis transmembrane regulator-dependent Cl- secretion by human airway epithelia. | Schwarzer C, Wong S, Shi J, Matthes E, Illek B, Ianowski JP, Arant RJ, Isacoff E, Vais H, Foskett JK, Maiellaro I, Hofer AM, Machen TE | The Journal of biological chemistry | 20739289 | J Biol Chem | 2010 Nov 5 |
| Disassembly of a core-satellite nanoassembled substrate for colorimetric biomolecular detection. | Waldeisen JR, Wang T, Ross BM, Lee LP | ACS nano | 21667984 | ACS Nano | 2011 Jul 26 |
| Optical control of neuronal activity. | Szobota S, Isacoff EY | Annual review of biophysics | 20192766 | Annu Rev Biophys | 2010 |
| LiGluR restores visual responses in rodent models of inherited blindness. | Caporale N, Kolstad KD, Lee T, Tochitsky I, Dalkara D, Trauner D, Kramer R, Dan Y, Isacoff EY, Flannery JG | Molecular therapy : the journal of the American Society of Gene Therapy | 21610698 | Mol Ther | 2011 Jul |
| Photochromic blockers of voltage-gated potassium channels. | Banghart MR, Mourot A, Fortin DL, Yao JZ, Kramer RH, Trauner D | Angewandte Chemie (International ed. in English) | 19882609 | Angew Chem Int Ed Engl | 2009 |
| Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. | Wu P, Shui W, Carlson BL, Hu N, Rabuka D, Lee J, Bertozzi CR | Proceedings of the National Academy of Sciences of the United States of America | 19202059 | Proc Natl Acad Sci U S A | 2009 Mar 3 |
| Plasmon resonance energy transfer (PRET)-based molecular imaging of cytochrome c in living cells. | Choi Y, Kang T, Lee LP | Nano letters | 19093833 | Nano Lett | 2009 Jan |
| New photochemical tools for controlling neuronal activity. | Kramer RH, Fortin DL, Trauner D | Current opinion in neurobiology | 19828309 | Curr Opin Neurobiol | 2009 Oct |
| Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration. | Byrne LC, Dalkara D, Luna G, Fisher SK, Clérin E, Sahel JA, Léveillard T, Flannery JG | The Journal of clinical investigation | 25415434 | J Clin Invest | 2015 Jan |
| Optopharmacological tools for restoring visual function in degenerative retinal diseases. | Tochitsky I, Kramer RH | Current opinion in neurobiology | 25706312 | Curr Opin Neurobiol | 2015 Oct |
| A spinal opsin controls early neural activity and drives a behavioral light response. | Friedmann D, Hoagland A, Berlin S, Isacoff EY | Current biology : CB | 25484291 | Curr Biol | 2015 Jan 5 |
| Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells. | Gaub BM, Berry MH, Holt AE, Reiner A, Kienzler MA, Dolgova N, Nikonov S, Aguirre GD, Beltran WA, Flannery JG, Isacoff EY | Proceedings of the National Academy of Sciences of the United States of America | 25489083 | Proc Natl Acad Sci U S A | 2014 Dec 23 |
| Miniaturized integration of a fluorescence microscope. | Ghosh KK, Burns LD, Cocker ED, Nimmerjahn A, Ziv Y, Gamal AE, Schnitzer MJ | Nature methods | 21909102 | Nat Methods | 2011 Sep 11 |
| Regulating enzymatic activity with a photoswitchable affinity label. | Harvey JH, Trauner D | Chembiochem : a European journal of chemical biology | 18085544 | Chembiochem | 2008 Jan 25 |
| Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous. | Dalkara D, Kolstad KD, Caporale N, Visel M, Klimczak RR, Schaffer DV, Flannery JG | Molecular therapy : the journal of the American Society of Gene Therapy | 19672248 | Mol Ther | 2009 Dec |
| Pseudomonas aeruginosa Inhibition of Flagellin-activated NF-kappaB and interleukin-8 by human airway epithelial cells. | Pena J, Fu Z, Schwarzer C, Machen TE | Infection and immunity | 19451246 | Infect Immun | 2009 Jul |
| Photoswitching of cell surface receptors using tethered ligands. | Reiner A, Isacoff EY | Methods in molecular biology (Clifton, N.J.) | 24718794 | Methods Mol Biol | 2014 |
| Conformational pathway provides unique sensitivity to a synaptic mGluR. | Habrian CH, Levitz J, Vyklicky V, Fu Z, Hoagland A, McCort-Tranchepain I, Acher F, Isacoff EY | Nature communications | 31804469 | Nat Commun | 2019 Dec 5 |
| Light-Switchable Ion Channels and Receptors for Optogenetic Interrogation of Neuronal Signaling. | Lin WC, Kramer RH | Bioconjugate chemistry | 29465988 | Bioconjug Chem | 2018 Apr 18 |
| Sequential Steps of CRAC Channel Activation. | Palty R, Fu Z, Isacoff EY | Cell reports | 28564609 | Cell Rep | 2017 May 30 |
| Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors. | Levitz J, Broichhagen J, Leippe P, Konrad D, Trauner D, Isacoff EY | Proceedings of the National Academy of Sciences of the United States of America | 28396447 | Proc Natl Acad Sci U S A | 2017 Apr 25 |
| Restoring visual function to the blind retina with a potent, safe and long-lasting photoswitch. | Tochitsky I, Trautman J, Gallerani N, Malis JG, Kramer RH | Scientific reports | 28406473 | Sci Rep | 2017 Apr 13 |
| Optical control of sphingosine-1-phosphate formation and function. | Morstein J, Hill RZ, Novak AJE, Feng S, Norman DD, Donthamsetti PC, Frank JA, Harayama T, Williams BM, Parrill AL, Tigyi GJ, Riezman H, Isacoff EY, Bautista DM, Trauner D | Nature chemical biology | 31036923 | Nat Chem Biol | 2019 Jun |
| Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand. | Broichhagen J, Damijonaitis A, Levitz J, Sokol KR, Leippe P, Konrad D, Isacoff EY, Trauner D | ACS central science | 27162996 | ACS Cent Sci | 2015 Oct 28 |
| Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor. | Donthamsetti PC, Broichhagen J, Vyklicky V, Stanley C, Fu Z, Visel M, Levitz JL, Javitch JA, Trauner D, Isacoff EY | Journal of the American Chemical Society | 31291105 | J Am Chem Soc | 2019 Jul 24 |
| Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity. | Gaub BM, Berry MH, Holt AE, Isacoff EY, Flannery JG | Molecular therapy : the journal of the American Society of Gene Therapy | 26137852 | Mol Ther | 2015 Oct |
| A new strategy to photoactivate green fluorescent protein. | Groff D, Wang F, Jockusch S, Turro NJ, Schultz PG | Angewandte Chemie (International ed. in English) | 20836111 | Angew Chem Int Ed Engl | 2010 Oct 11 |
| Two-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkey. | Heider B, Nathanson JL, Isacoff EY, Callaway EM, Siegel RM | PloS one | 21079806 | PLoS One | 2010 Nov 4 |
| Filtering of visual information in the tectum by an identified neural circuit. | Del Bene F, Wyart C, Robles E, Tran A, Looger L, Scott EK, Isacoff EY, Baier H | Science (New York, N.Y.) | 21030657 | Science | 2010 Oct 29 |
| Photochemical restoration of visual responses in blind mice. | Polosukhina A, Litt J, Tochitsky I, Nemargut J, Sychev Y, De Kouchkovsky I, Huang T, Borges K, Trauner D, Van Gelder RN, Kramer RH | Neuron | 22841312 | Neuron | 2012 Jul 26 |
| Optogenetic dissection of a behavioural module in the vertebrate spinal cord. | Wyart C, Del Bene F, Warp E, Scott EK, Trauner D, Baier H, Isacoff EY | Nature | 19759620 | Nature | 2009 Sep 17 |
| Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR. | Numano R, Szobota S, Lau AY, Gorostiza P, Volgraf M, Roux B, Trauner D, Isacoff EY | Proceedings of the National Academy of Sciences of the United States of America | 19342491 | Proc Natl Acad Sci U S A | 2009 Apr 21 |
| Nanoplasmonic gene regulation. | Lee SE, Lee LP | Current opinion in chemical biology | 20888286 | Curr Opin Chem Biol | 2010 Oct |
| Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid. | Comoglio Y, Levitz J, Kienzler MA, Lesage F, Isacoff EY, Sandoz G | Proceedings of the National Academy of Sciences of the United States of America | 25197053 | Proc Natl Acad Sci U S A | 2014 Sep 16 |
| Focal damage to macaque photoreceptors produces persistent visual loss. | Strazzeri JM, Hunter JJ, Masella BD, Yin L, Fischer WS, DiLoreto DA Jr, Libby RT, Williams DR, Merigan WH | Experimental eye research | 24316158 | Exp Eye Res | 2014 Feb |
| Adeno-associated virus vectors and neurological gene therapy. | Ojala DS, Amara DP, Schaffer DV | The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry | 24557878 | Neuroscientist | 2015 Feb |
| Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy. | Reiner A, Isacoff EY | Nature chemical biology | 24561661 | Nat Chem Biol | 2014 Apr |
| Light at the end of the channel: optical manipulation of intrinsic neuronal excitability with chemical photoswitches. | Mourot A, Tochitsky I, Kramer RH | Frontiers in molecular neuroscience | 23518818 | Front Mol Neurosci | 2013 |
| Overlap of abnormal photoreceptor development and progressive degeneration in Leber congenital amaurosis caused by NPHP5 mutation. | Downs LM, Scott EM, Cideciyan AV, Iwabe S, Dufour V, Gardiner KL, Genini S, Marinho LF, Sumaroka A, Kosyk MS, Swider M, Aguirre GK, Jacobson SG, Beltran WA, Aguirre GD | Human molecular genetics | 27506978 | Hum Mol Genet | 2016 Oct 1 |
| A Toolkit for Orthogonal and in vivo Optical Manipulation of Ionotropic Glutamate Receptors. | Levitz J, Popescu AT, Reiner A, Isacoff EY | Frontiers in molecular neuroscience | 26869877 | Front Mol Neurosci | 2016 |
| N-(3-Oxo-acyl)-homoserine lactone induces apoptosis primarily through a mitochondrial pathway in fibroblasts. | Neely AM, Zhao G, Schwarzer C, Stivers NS, Whitt AG, Meng S, Burlison JA, Machen TE, Li C | Cellular microbiology | 28876505 | Cell Microbiol | 2018 Jan |
| AAV ancestral reconstruction library enables selection of broadly infectious viral variants. | Santiago-Ortiz J, Ojala DS, Westesson O, Weinstein JR, Wong SY, Steinsapir A, Kumar S, Holmes I, Schaffer DV | Gene therapy | 26186661 | Gene Ther | 2015 Dec |
| Scanless two-photon excitation of channelrhodopsin-2. | Papagiakoumou E, Anselmi F, Bègue A, de Sars V, Glückstad J, Isacoff EY, Emiliani V | Nature methods | 20852649 | Nat Methods | 2010 Oct |
| Imaging light responses of retinal ganglion cells in the living mouse eye. | Yin L, Geng Y, Osakada F, Sharma R, Cetin AH, Callaway EM, Williams DR, Merigan WH | Journal of neurophysiology | 23407356 | J Neurophysiol | 2013 May |
| Optical control of metabotropic glutamate receptors. | Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY | Nature neuroscience | 23455609 | Nat Neurosci | 2013 Apr |
| AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting. | Hastie P, Ulbrich MH, Wang HL, Arant RJ, Lau AG, Zhang Z, Isacoff EY, Chen L | Proceedings of the National Academy of Sciences of the United States of America | 23479622 | Proc Natl Acad Sci U S A | 2013 Mar 26 |
| Emergence of patterned activity in the developing zebrafish spinal cord. | Warp E, Agarwal G, Wyart C, Friedmann D, Oldfield CS, Conner A, Del Bene F, Arrenberg AB, Baier H, Isacoff EY | Current biology : CB | 22197243 | Curr Biol | 2012 Jan 24 |
| Optogenetic activation of LiGluR-expressing astrocytes evokes anion channel-mediated glutamate release. | Li D, Hérault K, Isacoff EY, Oheim M, Ropert N | The Journal of physiology | 22219341 | J Physiol | 2012 Feb 15 |
| AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa. | Dalkara D, Kolstad KD, Guerin KI, Hoffmann NV, Visel M, Klimczak RR, Schaffer DV, Flannery JG | Molecular therapy : the journal of the American Society of Gene Therapy | 21522134 | Mol Ther | 2011 Sep |
| Engineering light-regulated ion channels. | Fortin DL, Dunn TW, Kramer RH | Cold Spring Harbor protocols | 21632787 | Cold Spring Harb Protoc | 2011 Jun 1 |
| Omnidirectional 3D nanoplasmonic optical antenna array via soft-matter transformation. | Ross BM, Wu LY, Lee LP | Nano letters | 21661733 | Nano Lett | 2011 Jul 13 |
| Targeted transgene expression in muller glia of normal and diseased retinas using lentiviral vectors. | Greenberg KP, Geller SF, Schaffer DV, Flannery JG | Investigative ophthalmology & visual science | 17389520 | Invest Ophthalmol Vis Sci | 2007 Apr |
| Colloid-guided assembly of oriented 3D neuronal networks. | Pautot S, Wyart C, Isacoff EY | Nature methods | 18641658 | Nat Methods | 2008 Aug |
| New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo. | Rush JS, Bertozzi CR | Journal of the American Chemical Society | 18722427 | J Am Chem Soc | 2008 Sep 17 |
| Nanoengineering ion channels for optical control. | Gorostiza P, Isacoff EY | Physiology (Bethesda, Md.) | 18927200 | Physiology (Bethesda) | 2008 Oct |
| Engineering a light-regulated GABAA receptor for optical control of neural inhibition. | Lin WC, Davenport CM, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH | ACS chemical biology | 24819442 | ACS Chem Biol | 2014 Jul 18 |
| Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia. | Schwarzer C, Ravishankar B, Patanwala M, Shuai S, Fu Z, Illek B, Fischer H, Machen TE | American journal of physiology. Cell physiology | 24598360 | Am J Physiol Cell Physiol | 2014 May 1 |
| Rapid optical control of nociception with an ion-channel photoswitch. | Mourot A, Fehrentz T, Le Feuvre Y, Smith CM, Herold C, Dalkara D, Nagy F, Trauner D, Kramer RH | Nature methods | 22343342 | Nat Methods | 2012 Feb 19 |
| Biologically functional cationic phospholipid-gold nanoplasmonic carriers of RNA. | Lee SE, Sasaki DY, Perroud TD, Yoo D, Patel KD, Lee LP | Journal of the American Chemical Society | 19746908 | J Am Chem Soc | 2009 Oct 7 |
| Optical control of zebrafish behavior with halorhodopsin. | Arrenberg AB, Del Bene F, Baier H | Proceedings of the National Academy of Sciences of the United States of America | 19805086 | Proc Natl Acad Sci U S A | 2009 Oct 20 |
| In vivo brain imaging using a portable 2.9 g two-photon microscope based on a microelectromechanical systems scanning mirror. | Piyawattanametha W, Cocker ED, Burns LD, Barretto RP, Jung JC, Ra H, Solgaard O, Schnitzer MJ | Optics letters | 19649080 | Opt Lett | 2009 Aug 1 |
| Bioinspired nanocorals with decoupled cellular targeting and sensing functionality. | Wu LY, Ross BM, Hong S, Lee LP | Small (Weinheim an der Bergstrasse, Germany) | 20108232 | Small | 2010 Feb 22 |
| Optical control of calcium affinity in a spiroamido-rhodamine based calcium chelator. | Wu L, Dai Y, Marriott G | Organic letters | 21417245 | Org Lett | 2011 Apr 15 |
| Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway. | Liu CY, Fraser SE, Koos DS | The Journal of comparative neurology | 19565523 | J Comp Neurol | 2009 Sep 1 |
| Restoring visual function to blind mice with a photoswitch that exploits electrophysiological remodeling of retinal ganglion cells. | Tochitsky I, Polosukhina A, Degtyar VE, Gallerani N, Smith CM, Friedman A, Van Gelder RN, Trauner D, Kaufer D, Kramer RH | Neuron | 24559673 | Neuron | 2014 Feb 19 |
| A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor. | Kienzler MA, Reiner A, Trautman E, Yoo S, Trauner D, Isacoff EY | Journal of the American Chemical Society | 24171511 | J Am Chem Soc | 2013 Nov 27 |
| Assembly stoichiometry of the GluK2/GluK5 kainate receptor complex. | Reiner A, Arant RJ, Isacoff EY | Cell reports | 22509486 | Cell Rep | 2012 Mar 29 |
| Rational design, synthesis, and characterization of highly fluorescent optical switches for high-contrast optical lock-in detection (OLID) imaging microscopy in living cells. | Petchprayoon C, Yan Y, Mao S, Marriott G | Bioorganic & medicinal chemistry | 20674372 | Bioorg Med Chem | 2011 Feb 1 |
| Rapid feedback regulation of synaptic efficacy during high-frequency activity at the Drosophila larval neuromuscular junction. | Kauwe G, Isacoff EY | Proceedings of the National Academy of Sciences of the United States of America | 23674684 | Proc Natl Acad Sci U S A | 2013 May 28 |
| Optogenetic Retinal Gene Therapy with the Light Gated GPCR Vertebrate Rhodopsin. | Gaub BM, Berry MH, Visel M, Holt A, Isacoff EY, Flannery JG | Methods in molecular biology (Clifton, N.J.) | 29188513 | Methods Mol Biol | 2018 |
| Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor. | Berry MH, Holt A, Levitz J, Broichhagen J, Gaub BM, Visel M, Stanley C, Aghi K, Kim YJ, Cao K, Kramer RH, Trauner D, Flannery J, Isacoff EY | Nature communications | 29192252 | Nat Commun | 2017 Nov 30 |
| Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa. | Marsili S, Genini S, Sudharsan R, Gingrich J, Aguirre GD, Beltran WA | PloS one | 25695253 | PLoS One | 2015 |
| A family of photoswitchable NMDA receptors. | Berlin S, Szobota S, Reiner A, Carroll EC, Kienzler MA, Guyon A, Xiao T, Trauner D, Isacoff EY | eLife | 26929991 | Elife | 2016 Mar 1 |
| Measuring Behavioral Individuality in the Acoustic Startle Behavior in Zebrafish. | Pantoja C, Hoagland A, Carroll E, Schoppik D, Isacoff EY | Bio-protocol | 28752108 | Bio Protoc | 2017 Apr 5 |
| Lateral Inhibition in the Vertebrate Retina: The Case of the Missing Neurotransmitter. | Kramer RH, Davenport CM | PLoS biology | 26656622 | PLoS Biol | 2015 Dec |
| Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors. | Levitz J, Habrian C, Bharill S, Fu Z, Vafabakhsh R, Isacoff EY | Neuron | 27641494 | Neuron | 2016 Oct 5 |
| Neuromodulatory Regulation of Behavioral Individuality in Zebrafish. | Pantoja C, Hoagland A, Carroll EC, Karalis V, Conner A, Isacoff EY | Neuron | 27397519 | Neuron | 2016 Aug 3 |
| Controlling ionotropic and metabotropic glutamate receptors with light: principles and potential. | Reiner A, Levitz J, Isacoff EY | Current opinion in pharmacology | 25573450 | Curr Opin Pharmacol | 2015 Feb |
| Restoration of high-sensitivity and adapting vision with a cone opsin. | Berry MH, Holt A, Salari A, Veit J, Visel M, Levitz J, Aghi K, Gaub BM, Sivyer B, Flannery JG, Isacoff EY | Nature communications | 30874546 | Nat Commun | 2019 Mar 15 |
| Conformational dynamics of a class C G-protein-coupled receptor. | Vafabakhsh R, Levitz J, Isacoff EY | Nature | 26258295 | Nature | 2015 Aug 27 |
| Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone. | Schwarzer C, Fu Z, Morita T, Whitt AG, Neely AM, Li C, Machen TE | The Journal of biological chemistry | 25627690 | J Biol Chem | 2015 Mar 13 |
| Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics. | Carroll EC, Berlin S, Levitz J, Kienzler MA, Yuan Z, Madsen D, Larsen DS, Isacoff EY | Proceedings of the National Academy of Sciences of the United States of America | 25653339 | Proc Natl Acad Sci U S A | 2015 Feb 17 |
| Photochemical approaches to vision restoration. | Van Gelder RN | Vision research | 25680758 | Vision Res | 2015 Jun |
| Optical switches for remote and noninvasive control of cell signaling. | Gorostiza P, Isacoff EY | Science (New York, N.Y.) | 18927384 | Science | 2008 Oct 17 |
| Biomolecular plasmonics for quantitative biology and nanomedicine. | Lee SE, Lee LP | Current opinion in biotechnology | 20801636 | Curr Opin Biotechnol | 2010 Aug |
| Alternative splicing of neuroligin regulates the rate of presynaptic differentiation. | Lee H, Dean C, Isacoff E | The Journal of neuroscience : the official journal of the Society for Neuroscience | 20739565 | J Neurosci | 2010 Aug 25 |
| A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. | Janovjak H, Szobota S, Wyart C, Trauner D, Isacoff EY | Nature neuroscience | 20581843 | Nat Neurosci | 2010 Aug |
| A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells. | Klimczak RR, Koerber JT, Dalkara D, Flannery JG, Schaffer DV | PloS one | 19826483 | PLoS One | 2009 Oct 14 |
| Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons. | Peled ES, Isacoff EY | Nature neuroscience | 21378971 | Nat Neurosci | 2011 Apr |
| Optogenetic photochemical control of designer K+ channels in mammalian neurons. | Fortin DL, Dunn TW, Fedorchak A, Allen D, Montpetit R, Banghart MR, Trauner D, Adelman JP, Kramer RH | Journal of neurophysiology | 21525363 | J Neurophysiol | 2011 Jul |
| High-contrast fluorescence imaging in fixed and living cells using optimized optical switches. | Wu L, Dai Y, Jiang X, Petchprayoon C, Lee JE, Jiang T, Yan Y, Marriott G | PloS one | 23755140 | PLoS One | 2013 |
| In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous. | Dalkara D, Byrne LC, Klimczak RR, Visel M, Yin L, Merigan WH, Flannery JG, Schaffer DV | Science translational medicine | 23761039 | Sci Transl Med | 2013 Jun 12 |
| Visualizing mammalian brain area interactions by dual-axis two-photon calcium imaging. | Lecoq J, Savall J, Vučinić D, Grewe BF, Kim H, Li JZ, Kitch LJ, Schnitzer MJ | Nature neuroscience | 25402858 | Nat Neurosci | 2014 Dec |
| The expression pattern of systemically injected AAV9 in the developing mouse retina is determined by age. | Byrne LC, Lin YJ, Lee T, Schaffer DV, Flannery JG | Molecular therapy : the journal of the American Society of Gene Therapy | 25224467 | Mol Ther | 2015 Feb |
| Optogenetic techniques for the study of native potassium channels. | Sandoz G, Levitz J | Frontiers in molecular neuroscience | 23596388 | Front Mol Neurosci | 2013 |
| Experience, circuit dynamics, and forebrain recruitment in larval zebrafish prey capture. | Oldfield CS, Grossrubatscher I, Chávez M, Hoagland A, Huth AR, Carroll EC, Prendergast A, Qu T, Gallant JL, Wyart C, Isacoff EY | eLife | 32985972 | Elife | 2020 Sep 28 |
| Pseudomonas aeruginosa homoserine lactone triggers apoptosis and Bak/Bax-independent release of mitochondrial cytochrome C in fibroblasts. | Schwarzer C, Fu Z, Shuai S, Babbar S, Zhao G, Li C, Machen TE | Cellular microbiology | 24438098 | Cell Microbiol | 2014 Jul |
| Reversible optical control of cyanine fluorescence in fixed and living cells: optical lock-in detection immunofluorescence imaging microscopy. | Yan Y, Petchprayoon C, Mao S, Marriott G | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 23267183 | Philos Trans R Soc Lond B Biol Sci | 2013 Feb 5 |
| The Brain Prize 2013: the optogenetics revolution. | Reiner A, Isacoff EY | Trends in neurosciences | 24054067 | Trends Neurosci | 2013 Oct |
| A Comprehensive Optogenetic Pharmacology Toolkit for In Vivo Control of GABA(A) Receptors and Synaptic Inhibition. | Lin WC, Tsai MC, Davenport CM, Smith CM, Veit J, Wilson NM, Adesnik H, Kramer RH | Neuron | 26606997 | Neuron | 2015 Dec 2 |
| Photoactivatable genetically encoded calcium indicators for targeted neuronal imaging. | Berlin S, Carroll EC, Newman ZL, Okada HO, Quinn CM, Kallman B, Rockwell NC, Martin SS, Lagarias JC, Isacoff EY | Nature methods | 26167640 | Nat Methods | 2015 Sep |
| Stoichiometry and specific assembly of Best ion channels. | Bharill S, Fu Z, Palty R, Isacoff EY | Proceedings of the National Academy of Sciences of the United States of America | 24748110 | Proc Natl Acad Sci U S A | 2014 Apr 29 |
| N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins. | Zhao G, Neely AM, Schwarzer C, Lu H, Whitt AG, Stivers NS, Burlison JA, White C, Machen TE, Li C | Oncotarget | 26758417 | Oncotarget | 2016 Feb 2 |
| Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist. | Donthamsetti PC, Winter N, Schönberger M, Levitz J, Stanley C, Javitch JA, Isacoff EY, Trauner D | Journal of the American Chemical Society | 29166564 | J Am Chem Soc | 2017 Dec 27 |
| Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system. | Xiao T, Ackerman CM, Carroll EC, Jia S, Hoagland A, Chan J, Thai B, Liu CS, Isacoff EY, Chang CJ | Nature chemical biology | 29867144 | Nat Chem Biol | 2018 Jul |
| Restoring Vision to the Blind with Chemical Photoswitches. | Tochitsky I, Kienzler MA, Isacoff E, Kramer RH | Chemical reviews | 29874052 | Chem Rev | 2018 Nov 14 |
| Input-Specific Plasticity and Homeostasis at the Drosophila Larval Neuromuscular Junction. | Newman ZL, Hoagland A, Aghi K, Worden K, Levy SL, Son JH, Lee LP, Isacoff EY | Neuron | 28285823 | Neuron | 2017 Mar 22 |
| Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells. | Marriott G, Mao S, Sakata T, Ran J, Jackson DK, Petchprayoon C, Gomez TJ, Warp E, Tulyathan O, Aaron HL, Isacoff EY, Yan Y | Proceedings of the National Academy of Sciences of the United States of America | 19004775 | Proc Natl Acad Sci U S A | 2008 Nov 18 |
| Remote optical switch for localized and selective control of gene interference. | Lee SE, Liu GL, Kim F, Lee LP | Nano letters | 19128006 | Nano Lett | 2009 Feb |
| Genetic and optical targeting of neural circuits and behavior--zebrafish in the spotlight. | Baier H, Scott EK | Current opinion in neurobiology | 19781935 | Curr Opin Neurobiol | 2009 Oct |
| Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling. | Sandoz G, Levitz J, Kramer RH, Isacoff EY | Neuron | 22726831 | Neuron | 2012 Jun 21 |
| Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors. | Tochitsky I, Banghart MR, Mourot A, Yao JZ, Gaub B, Kramer RH, Trauner D | Nature chemistry | 22270644 | Nat Chem | 2012 Jan 10 |
| Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9. | Dalkara D, Byrne LC, Lee T, Hoffmann NV, Schaffer DV, Flannery JG | Gene therapy | 22011645 | Gene Ther | 2012 Feb |
| Photonic gene circuits by optically addressable siRNA-Au nanoantennas. | Lee SE, Sasaki DY, Park Y, Xu R, Brennan JS, Bissell MJ, Lee LP | ACS nano | 22827439 | ACS Nano | 2012 Sep 25 |
| The mitochondrial Na(+)/Ca(2+) exchanger. | Palty R, Sekler I | Cell calcium | 22430014 | Cell Calcium | 2012 Jul |
| Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO). | Barber DM, Schönberger M, Burgstaller J, Levitz J, Weaver CD, Isacoff EY, Baier H, Trauner D | Chemical science | 28090283 | Chem Sci | 2016 |
| Precise modulation of neuronal activity with synthetic photoswitchable ligands. | Kienzler MA, Isacoff EY | Current opinion in neurobiology | 28690101 | Curr Opin Neurobiol | 2017 Aug |
| Photochemical Restoration of Light Sensitivity in the Degenerated Canine Retina. | Nikonov S, Dolgova N, Sudharsan R, Tochitsky I, Iwabe S, Guzman JM, Van Gelder RN, Kramer RH, Aguirre GD, Beltran WA | Pharmaceutics | 36559205 | Pharmaceutics | 2022 Dec 3 |
| Formation of lipid bilayers inside microfluidic channel array for monitoring membrane-embedded nanopores of phi29 DNA packaging nanomotor. | Shim JS, Geng J, Ahn CH, Guo P | Biomedical microdevices | 22773160 | Biomed Microdevices | 2012 Oct |
| Robust properties of membrane-embedded connector channel of bacterial virus phi29 DNA packaging motor. | Jing P, Haque F, Vonderheide AP, Montemagno C, Guo P | Molecular bioSystems | 20523933 | Mol Biosyst | 2010 Oct |
| Oriented insertion of phi29 N-hexahistidine-tagged gp10 connector protein assemblies into C20BAS bolalipid membrane vesicles. | Hyun SH, Kim HK, Kim JM, Thompson DH | Journal of the American Chemical Society | 20715817 | J Am Chem Soc | 2010 Dec 8 |
| One-way traffic of a viral motor channel for double-stranded DNA translocation. | Jing P, Haque F, Shu D, Montemagno C, Guo P | Nano letters | 20722407 | Nano Lett | 2010 Sep 8 |
| Translocation of double-stranded DNA through membrane-adapted phi29 motor protein nanopores. | Wendell D, Jing P, Geng J, Subramaniam V, Lee TJ, Montemagno C, Guo P | Nature nanotechnology | 19893523 | Nat Nanotechnol | 2009 Nov |
| Highly Sensitive, Mechanically Stable Nanopore Sensors for DNA Analysis. | Venkatesan BM, Dorvel B, Yemenicioglu S, Watkins N, Petrov I, Bashir R | Advanced materials (Deerfield Beach, Fla.) | 20098720 | Adv Mater | 2009 Jul 20 |
| Adjustable ellipsoid nanoparticles assembled from re-engineered connectors of the bacteriophage phi29 DNA packaging motor. | Xiao F, Cai Y, Wang JC, Green D, Cheng RH, Demeler B, Guo P | ACS nano | 19634910 | ACS Nano | 2009 Aug 25 |
| Engineering of the fluorescent-energy-conversion arm of phi29 DNA packaging motor for single-molecule studies. | Lee TJ, Zhang H, Chang CL, Savran C, Guo P | Small (Weinheim an der Bergstrasse, Germany) | 19743427 | Small | 2009 Nov |
| Evaluation of end-capped DNA modules for pRNA capture and functionalization. | Laing BM, Bergstrom DE | Bioconjugate chemistry | 22443238 | Bioconjug Chem | 2012 Apr 18 |
| Solid-State and Biological Nanopore for Real-Time Sensing of Single Chemical and Sequencing of DNA. | Haque F, Li J, Wu HC, Liang XJ, Guo P | Nano today | 23504223 | Nano Today | 2013 Feb |
| Modular assembly of chimeric phi29 packaging RNAs that support DNA packaging. | Fang Y, Shu D, Xiao F, Guo P, Qin PZ | Biochemical and biophysical research communications | 18514064 | Biochem Biophys Res Commun | 2008 Aug 8 |
| Construction of bacteriophage phi29 DNA packaging motor and its applications in nanotechnology and therapy. | Lee TJ, Schwartz C, Guo P | Annals of biomedical engineering | 19495981 | Ann Biomed Eng | 2009 Oct |
| Nanomedicine in ophthalmology: the new frontier. | Zarbin MA, Montemagno C, Leary JF, Ritch R | American journal of ophthalmology | 20670739 | Am J Ophthalmol | 2010 Aug |
| Fabrication of massive sheets of single layer patterned arrays using lipid directed reengineered phi29 motor dodecamer. | Xiao F, Sun J, Coban O, Schoen P, Wang JC, Cheng RH, Guo P | ACS nano | 19206255 | ACS Nano | 2009 Jan 27 |
| Engineering RNA for targeted siRNA delivery and medical application. | Guo P, Coban O, Snead NM, Trebley J, Hoeprich S, Guo S, Shu Y | Advanced drug delivery reviews | 20230868 | Adv Drug Deliv Rev | 2010 Apr 30 |
| Design and application of single fluorophore dual-view imaging system containing both the objective- and prism-type TIRF. | Zhang H, Shu D, Wang W, Guo P | Proceedings of SPIE--the International Society for Optical Engineering | 20436791 | Proc SPIE Int Soc Opt Eng | 2010 |
| Lipid bilayer coated Al(2)O(3) nanopore sensors: towards a hybrid biological solid-state nanopore. | Venkatesan BM, Polans J, Comer J, Sridhar S, Wendell D, Aksimentiev A, Bashir R | Biomedical microdevices | 21487665 | Biomed Microdevices | 2011 Aug |
| Nanotechnology in ophthalmology. | Zarbin MA, Montemagno C, Leary JF, Ritch R | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie | 20871642 | Can J Ophthalmol | 2010 Oct |
| Uniqueness, advantages, challenges, solutions, and perspectives in therapeutics applying RNA nanotechnology. | Guo P, Haque F, Hallahan B, Reif R, Li H | Nucleic acid therapeutics | 22913595 | Nucleic Acid Ther | 2012 Aug |
| Reversible switching of pRNA activity on the DNA packaging motor of bacteriophage phi29. | Ko SH, Chen Y, Shu D, Guo P, Mao C | Journal of the American Chemical Society | 19049308 | J Am Chem Soc | 2008 Dec 31 |
| Conformational flexibility facilitates self-assembly of complex DNA nanostructures. | Zhang C, Su M, He Y, Zhao X, Fang PA, Ribbe AE, Jiang W, Mao C | Proceedings of the National Academy of Sciences of the United States of America | 18667705 | Proc Natl Acad Sci U S A | 2008 Aug 5 |
| Capture and alignment of phi29 viral particles in sub-40 nanometer porous alumina membranes. | Moon JM, Akin D, Xuan Y, Ye PD, Guo P, Bashir R | Biomedical microdevices | 18770041 | Biomed Microdevices | 2009 Feb |
| Optimized method for the synthesis and purification of adenosine--folic acid conjugates for use as transcription initiators in the preparation of modified RNA. | Laing BM, Guo P, Bergstrom DE | Methods (San Diego, Calif.) | 21163352 | Methods | 2011 Jun |
| DNA Sensing using Nano-crystalline Surface Enhanced Al(2)O(3) Nanopore Sensors. | Venkatesan BM, Shah AB, Zuo JM, Bashir R | Advanced functional materials | 23335871 | Adv Funct Mater | 2010 Apr 23 |
| A boost for the emerging field of RNA nanotechnology. | Shukla GC, Haque F, Tor Y, Wilhelmsson LM, Toulmé JJ, Isambert H, Guo P, Rossi JJ, Tenenbaum SA, Shapiro BA | ACS nano | 21604810 | ACS Nano | 2011 May 24 |
| Viral nanomotors for packaging of dsDNA and dsRNA. | Guo P, Lee TJ | Molecular microbiology | 17501915 | Mol Microbiol | 2007 May |
| Crystallization and preliminary X-ray diffraction analysis of recombinant hepatitis E virus-like particle. | Wang CY, Miyazaki N, Yamashita T, Higashiura A, Nakagawa A, Li TC, Takeda N, Xing L, Hjalmarsson E, Friberg C, Liou DM, Sung YJ, Tsukihara T, Matsuura Y, Miyamura T, Cheng RH | Acta crystallographica. Section F, Structural biology and crystallization communications | 18391436 | Acta Crystallogr Sect F Struct Biol Cryst Commun | 2008 Apr 1 |
| Strand and nucleotide-dependent ATPase activity of gp16 of bacterial virus phi29 DNA packaging motor. | Lee TJ, Zhang H, Liang D, Guo P | Virology | 18701124 | Virology | 2008 Oct 10 |
| Construction of a laser combiner for dual fluorescent single molecule imaging of pRNA of phi29 DNA packaging motor. | Zhang H, Shu D, Browne M, Guo P | Biomedical microdevices | 19809878 | Biomed Microdevices | 2010 Feb |
| Bright-field analysis of phi29 DNA packaging motor using a magnetomechanical system. | Chang CL, Zhang H, Shu D, Guo P, Savran CA | Applied physics letters | 19529792 | Appl Phys Lett | 2008 Oct 13 |
| Phase separation in binary mixtures of bipolar and monopolar lipid dispersions revealed by 2H NMR spectroscopy, small angle x-ray scattering, and molecular theory. | Brownholland DP, Longo GS, Struts AV, Justice MJ, Szleifer I, Petrache HI, Brown MF, Thompson DH | Biophysical journal | 19917223 | Biophys J | 2009 Nov 18 |
| Effective electrophoretic mobilities and charges of anti-VEGF proteins determined by capillary zone electrophoresis. | Li SK, Liddell MR, Wen H | Journal of pharmaceutical and biomedical analysis | 21269789 | J Pharm Biomed Anal | 2011 Jun 1 |
| Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cells. | Shu Y, Cinier M, Shu D, Guo P | Methods (San Diego, Calif.) | 21320601 | Methods | 2011 Jun |
| Application of phi29 motor pRNA for targeted therapeutic delivery of siRNA silencing metallothionein-IIA and survivin in ovarian cancers. | Tarapore P, Shu Y, Guo P, Ho SM | Molecular therapy : the journal of the American Society of Gene Therapy | 21063391 | Mol Ther | 2011 Feb |
| "Push through one-way valve" mechanism of viral DNA packaging. | Zhang H, Schwartz C, De Donatis GM, Guo P | Advances in virus research | 22748815 | Adv Virus Res | 2012 |
| Novel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging. | Xiao F, Zhang H, Guo P | Nucleic acids research | 18940870 | Nucleic Acids Res | 2008 Nov |
| Improved plasmalogen synthesis using organobarium intermediates. | Van den Bossche J, Shin J, Thompson DH | The Journal of organic chemistry | 17539687 | J Org Chem | 2007 Jun 22 |
| The emerging field of RNA nanotechnology. | Guo P | Nature nanotechnology | 21102465 | Nat Nanotechnol | 2010 Dec |
| Approaches for stoichiometry and distance determination of nanometer bio-complex by dual-channel single molecule imaging. | Zhang H, Shu D, Browne M, Guo P | IEEE/NIH Life Science Systems and Applications Workshop. IEEE/NIH Life Science Systems and Applications Workshop | 20485472 | IEEE NIH Life Sci Syst Appl Workshop | 2009 Apr 9 |
| Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition. | Zhou J, Shu Y, Guo P, Smith DD, Rossi JJ | Methods (San Diego, Calif.) | 21256218 | Methods | 2011 Jun |
| Ultrastable pRNA hexameric ring gearing hexameric phi29 DNA-packaging motor by revolving without rotating and coiling. | Schwartz C, Guo P | Current opinion in biotechnology | 23683853 | Curr Opin Biotechnol | 2013 Aug |
| Accurate and Effective Live Bacteria Microarray Patterning on Thick Polycationic Polymer Layer Co-Patterned with HMDS. | Wong I, Ding X, Wu C, Ho CM | RSC advances | 23418622 | RSC Adv | 2012 |
| Multiplexed ion beam imaging of human breast tumors. | Angelo M, Bendall SC, Finck R, Hale MB, Hitzman C, Borowsky AD, Levenson RM, Lowe JB, Liu SD, Zhao S, Natkunam Y, Nolan GP | Nature medicine | 24584119 | Nat Med | 2014 Apr |
| Creation of functional micro/nano systems through top-down and bottom-up approaches. | Wong TS, Brough B, Ho CM | Molecular & cellular biomechanics : MCB | 19382535 | Mol Cell Biomech | 2009 Mar |
| Reversible regulation of aptamer activity with effector-responsive hairpin oligonucleotides. | Li N | Journal of laboratory automation | 22651934 | J Lab Autom | 2013 Feb |
| Tunable oscillations in the Purkinje neuron. | Abrams ZR, Warrier A, Wang Y, Trauner D, Zhang X | Physical review. E, Statistical, nonlinear, and soft matter physics | 22680496 | Phys Rev E Stat Nonlin Soft Matter Phys | 2012 Apr |
| Motile and non-motile sperm diagnostic manipulation using optoelectronic tweezers. | Ohta AT, Garcia M, Valley JK, Banie L, Hsu HY, Jamshidi A, Neale SL, Lue T, Wu MC | Lab on a chip | 20835428 | Lab Chip | 2010 Dec 7 |
| High throughput cell nanomechanics with mechanical imaging interferometry. | Reed J, Frank M, Troke JJ, Schmit J, Han S, Teitell MA, Gimzewski JK | Nanotechnology | 20737027 | Nanotechnology | 2008 Jun 11 |
| An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells. | Tsutsui H, Valamehr B, Hindoyan A, Qiao R, Ding X, Guo S, Witte ON, Liu X, Ho CM, Wu H | Nature communications | 21266967 | Nat Commun | 2011 Jan 25 |
| NanoPen: dynamic, low-power, and light-actuated patterning of nanoparticles. | Jamshidi A, Neale SL, Yu K, Pauzauskie PJ, Schuck PJ, Valley JK, Hsu HY, Ohta AT, Wu MC | Nano letters | 19588985 | Nano Lett | 2009 Aug |
| TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation. | Kuraishy AI, French SW, Sherman M, Herling M, Jones D, Wall R, Teitell MA | Proceedings of the National Academy of Sciences of the United States of America | 17548807 | Proc Natl Acad Sci U S A | 2007 Jun 12 |
| Operational Regimes and Physics Present in Optoelectronic Tweezers. | Valley JK, Jamshidi A, Ohta AT, Hsu HY, Wu MC | Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems | 19079767 | J Microelectromech Syst | 2008 Apr |
| Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas. | Frank MJ, Dawson DW, Bensinger SJ, Hong JS, Knosp WM, Xu L, Balatoni CE, Allen EL, Shen RR, Bar-Sagi D, Martin GR, Teitell MA | Blood | 19147787 | Blood | 2009 Mar 12 |
| Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NFκB. | Teh BE, French CT, Chen Y, Chen IG, Wu TH, Sagullo E, Chiou PY, Teitell MA, Miller JF, Gan YH | BMC microbiology | 24884837 | BMC Microbiol | 2014 May 6 |
| Use of cell morphology as early bioindicator for viral infection. | Ding X, Liu N, Matsuo K, Sun M, Zhao X | IET nanobiotechnology | 24888188 | IET Nanobiotechnol | 2014 Mar |
| Intracellular delivery of top-down fabricated tunable nano-plasmonic resonators. | Ota S, Wang S, Ryu J, Wang Y, Chen Y, Zhang X | Nanoscale | 24056760 | Nanoscale | 2013 Nov 7 |
| Cascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity. | Ding X, Sanchez DJ, Shahangian A, Al-Shyoukh I, Cheng G, Ho CM | International journal of nanomedicine | 22654513 | Int J Nanomedicine | 2012 |
| Preimplantation mouse embryo selection guided by light-induced dielectrophoresis. | Valley JK, Swinton P, Boscardin WJ, Lue TF, Rinaudo PF, Wu MC, Garcia MM | PloS one | 20405021 | PLoS One | 2010 Apr 13 |
| Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm. | Wong PK, Yu F, Shahangian A, Cheng G, Sun R, Ho CM | Proceedings of the National Academy of Sciences of the United States of America | 18356295 | Proc Natl Acad Sci U S A | 2008 Apr 1 |
| Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies. | Valamehr B, Jonas SJ, Polleux J, Qiao R, Guo S, Gschweng EH, Stiles B, Kam K, Luo TJ, Witte ON, Liu X, Dunn B, Wu H | Proceedings of the National Academy of Sciences of the United States of America | 18791068 | Proc Natl Acad Sci U S A | 2008 Sep 23 |
| Single-sided continuous optoelectrowetting (SCOEW) for droplet manipulation with light patterns. | Park SY, Teitell MA, Chiou EP | Lab on a chip | 20448870 | Lab Chip | 2010 Jul 7 |
| Trap profiles of projector based optoelectronic tweezers (OET) with HeLa cells. | Neale SL, Ohta AT, Hsu HY, Valley JK, Jamshidi A, Wu MC | Optics express | 19333286 | Opt Express | 2009 Mar 30 |
| Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control. | Honda Y, Ding X, Mussano F, Wiberg A, Ho CM, Nishimura I | Scientific reports | 24305548 | Sci Rep | 2013 Dec 5 |
| Cellular Signaling Analysis shows antiviral, ribavirin-mediated ribosomal signaling modulation. | Ding X, Krutzik PO, Ghaffari AA, Zhaozhi Y, Miranda D Jr, Cheng G, Ho CM, Nolan GP, Sanchez DJ | Antiviral research | 31513822 | Antiviral Res | 2019 Nov |
| When Medicine Meets Engineering-Paradigm Shifts in Diagnostics and Therapeutics. | Wang H, Silva A, Ho CM | Diagnostics (Basel, Switzerland) | 26835672 | Diagnostics (Basel) | 2013 Feb 27 |
| Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice. | Raval A, Behbehani GK, Nguyen le XT, Thomas D, Kusler B, Garbuzov A, Ramunas J, Holbrook C, Park CY, Blau H, Nolan GP, Artandi SE, Mitchell BS | PloS one | 26133370 | PLoS One | 2015 |
| A noninvasive, motility independent, sperm sorting method and technology to identify and retrieve individual viable nonmotile sperm for intracytoplasmic sperm injection. | Garcia MM, Ohta AT, Walsh TJ, Vittinghof E, Lin G, Wu MC, Lue TF | The Journal of urology | 20952004 | J Urol | 2010 Dec |
| Nanochromatography driven by the coffee ring effect. | Wong TS, Chen TH, Shen X, Ho CM | Analytical chemistry | 21288015 | Anal Chem | 2011 Mar 15 |
| High-speed droplet generation on demand driven by pulse laser-induced cavitation. | Park SY, Wu TH, Chen Y, Teitell MA, Chiou PY | Lab on a chip | 21290045 | Lab Chip | 2011 Mar 21 |
| Dependence of macroscopic wetting on nanoscopic surface textures. | Wong TS, Ho CM | Langmuir : the ACS journal of surfaces and colloids | 19842620 | Langmuir | 2009 Nov 17 |
| A light-induced dielectrophoretic droplet manipulation platform. | Park SY, Kalim S, Callahan C, Teitell MA, Chiou EP | Lab on a chip | 19865729 | Lab Chip | 2009 Nov 21 |
| Efficient dielectrophoretic patterning of embryonic stem cells in energy landscapes defined by hydrogel geometries. | Tsutsui H, Yu E, Marquina S, Valamehr B, Wong I, Wu H, Ho CM | Annals of biomedical engineering | 20614250 | Ann Biomed Eng | 2010 Dec |
| Surface molecular property modifications for poly(dimethylsiloxane) (PDMS) based microfluidic devices. | Wong I, Ho CM | Microfluidics and nanofluidics | 20357909 | Microfluid Nanofluidics | 2009 Sep 1 |
| AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling. | Sherman MH, Kuraishy AI, Deshpande C, Hong JS, Cacalano NA, Gatti RA, Manis JP, Damore MA, Pellegrini M, Teitell MA | Molecular cell | 20864035 | Mol Cell | 2010 Sep 24 |
| Single molecule transcription profiling with AFM. | Reed J, Mishra B, Pittenger B, Magonov S, Troke J, Teitell MA, Gimzewski JK | Nanotechnology | 20721301 | Nanotechnology | 2007 May 9 |
| Subcellular resolution mapping of endogenous cytokine secretion by nano-plasmonic-resonator sensor array. | Wang S, Ota S, Guo B, Ryu J, Rhodes C, Xiong Y, Kalim S, Zeng L, Chen Y, Teitell MA, Zhang X | Nano letters | 21780816 | Nano Lett | 2011 Aug 10 |
| Directing tissue morphogenesis via self-assembly of vascular mesenchymal cells. | Chen TH, Zhu X, Pan L, Zeng X, Garfinkel A, Tintut Y, Demer LL, Zhao X, Ho CM | Biomaterials | 23010575 | Biomaterials | 2012 Dec |
| Live cell interferometry reveals cellular dynamism during force propagation. | Reed J, Troke JJ, Schmit J, Han S, Teitell MA, Gimzewski JK | ACS nano | 19206480 | ACS Nano | 2008 May |
| Super-resolution imaging by random adsorbed molecule probes. | Wu D, Liu Z, Sun C, Zhang X | Nano letters | 18321073 | Nano Lett | 2008 Apr |
| Gradient lithography of engineered proteins to fabricate 2D and 3D cell culture microenvironments. | Wang S, Wong Po Foo C, Warrier A, Poo MM, Heilshorn SC, Zhang X | Biomedical microdevices | 19495986 | Biomed Microdevices | 2009 Oct |
| Molecular effects on boundary condition in micronanoliquid flows. | Ulmanella U, Ho CM | Physics of fluids (Woodbury, N.Y. : 1994) | 19547719 | Phys Fluids (1994) | 2008 Oct |
| Optically actuated thermocapillary movement of gas bubbles on an absorbing substrate. | Ohta AT, Jamshidi A, Valley JK, Hsu HY, Wu MC | Applied physics letters | 19750203 | Appl Phys Lett | 2007 Aug 14 |
| DNA diagnostics: nanotechnology-enhanced electrochemical detection of nucleic acids. | Wei F, Lillehoj PB, Ho CM | Pediatric research | 20075759 | Pediatr Res | 2010 May |
| Aptamer-based optical probes with separated molecular recognition and signal transduction modules. | Li N, Ho CM | Journal of the American Chemical Society | 18247609 | J Am Chem Soc | 2008 Feb 27 |
| Photothermal nanoblade for patterned cell membrane cutting. | Wu TH, Teslaa T, Teitell MA, Chiou PY | Optics express | 21164656 | Opt Express | 2010 Oct 25 |
| Systematic quantitative characterization of cellular responses induced by multiple signals. | Al-Shyoukh I, Yu F, Feng J, Yan K, Dubinett S, Ho CM, Shamma JS, Sun R | BMC systems biology | 21624115 | BMC Syst Biol | 2011 May 30 |
| Interrogating cell signalling network sensitively monitors cell fate transition during early differentiation of mouse embryonic stem cells. | Yue Z, Zhuang F, Liu YH, Ho CM | Science China. Life sciences | 20596958 | Sci China Life Sci | 2010 Jan |
| An agar gel membrane-PDMS hybrid microfluidic device for long term single cell dynamic study. | Wong I, Atsumi S, Huang WC, Wu TY, Hanai T, Lam ML, Tang P, Yang J, Liao JC, Ho CM | Lab on a chip | 20664845 | Lab Chip | 2010 Oct 21 |
| Normalization of mass cytometry data with bead standards. | Finck R, Simonds EF, Jager A, Krishnaswamy S, Sachs K, Fantl W, Pe'er D, Nolan GP, Bendall SC | Cytometry. Part A : the journal of the International Society for Analytical Cytology | 23512433 | Cytometry A | 2013 May |
| Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. | Bendall SC, Davis KL, Amir el-AD, Tadmor MD, Simonds EF, Chen TJ, Shenfeld DK, Nolan GP, Pe'er D | Cell | 24766814 | Cell | 2014 Apr 24 |
| Self-amplifying autocrine actions of BDNF in axon development. | Cheng PL, Song AH, Wong YH, Wang S, Zhang X, Poo MM | Proceedings of the National Academy of Sciences of the United States of America | 22025720 | Proc Natl Acad Sci U S A | 2011 Nov 8 |
| Coffee ring aptasensor for rapid protein detection. | Wen JT, Ho CM, Lillehoj PB | Langmuir : the ACS journal of surfaces and colloids | 23540796 | Langmuir | 2013 Jul 2 |
| Electrical impedance monitoring of photothermal porated mammalian cells. | Yamane D, Wu YC, Wu TH, Toshiyoshi H, Teitell MA, Chiou PY | Journal of laboratory automation | 23797097 | J Lab Autom | 2014 Feb |
| Application of fractional factorial designs to study drug combinations. | Jaynes J, Ding X, Xu H, Wong WK, Ho CM | Statistics in medicine | 22859316 | Stat Med | 2013 Jan 30 |
| Quantification of biomass and cell motion in human pluripotent stem cell colonies. | Zangle TA, Chun J, Zhang J, Reed J, Teitell MA | Biophysical journal | 23931307 | Biophys J | 2013 Aug 6 |
| Rapid, massively parallel single-cell drug response measurements via live cell interferometry. | Reed J, Chun J, Zangle TA, Kalim S, Hong JS, Pefley SE, Zheng X, Gimzewski JK, Teitell MA | Biophysical journal | 21889438 | Biophys J | 2011 Sep 7 |
| Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. | Qiu P, Simonds EF, Bendall SC, Gibbs KD Jr, Bruggner RV, Linderman MD, Sachs K, Nolan GP, Plevritis SK | Nature biotechnology | 21964415 | Nat Biotechnol | 2011 Oct 2 |
| Rapidly optimizing an aptamer based BoNT sensor by feedback system control (FSC) scheme. | Wei F, Bai B, Ho CM | Biosensors & bioelectronics | 21993141 | Biosens Bioelectron | 2011 Dec 15 |
| Floating electrode optoelectronic tweezers: Light-driven dielectrophoretic droplet manipulation in electrically insulating oil medium. | Park S, Pan C, Wu TH, Kloss C, Kalim S, Callahan CE, Teitell M, Chiou EP | Applied physics letters | 19479046 | Appl Phys Lett | 2008 Apr 14 |
| Automated identification of stratifying signatures in cellular subpopulations. | Bruggner RV, Bodenmiller B, Dill DL, Tibshirani RJ, Nolan GP | Proceedings of the National Academy of Sciences of the United States of America | 24979804 | Proc Natl Acad Sci U S A | 2014 Jul 1 |
| An application of a Hill-based response surface model for a drug combination experiment on lung cancer. | Ning S, Xu H, Al-Shyoukh I, Feng J, Sun R | Statistics in medicine | 24942112 | Stat Med | 2014 Oct 30 |
| Effects of cytoskeletal disruption on transport, structure, and rheology within mammalian cells. | Weihs D, Mason TG, Teitell MA | Physics of fluids (Woodbury, N.Y. : 1994) | 19816550 | Phys Fluids (1994) | 2007 |
| Phototransistor-based optoelectronic tweezers for dynamic cell manipulation in cell culture media. | Hsu HY, Ohta AT, Chiou PY, Jamshidi A, Neale SL, Wu MC | Lab on a chip | 20066243 | Lab Chip | 2010 Jan 21 |
| Placement of alkanethiol-capped Au nanoparticles using organic solvents. | Yim TJ, Choi H, Zhang X | Journal of colloid and interface science | 20332051 | J Colloid Interface Sci | 2010 Jun 1 |
| Continuous sorting of heterogeneous-sized embryoid bodies. | Lillehoj PB, Tsutsui H, Valamehr B, Wu H, Ho CM | Lab on a chip | 20376391 | Lab Chip | 2010 Jul 7 |
| Axon initiation and growth cone turning on bound protein gradients. | Mai J, Fok L, Gao H, Zhang X, Poo MM | The Journal of neuroscience : the official journal of the Society for Neuroscience | 19515913 | J Neurosci | 2009 Jun 10 |
| Parallel trapping of multiwalled carbon nanotubes with optoelectronic tweezers. | Pauzauskie PJ, Jamshidi A, Valley JK, Satcher JH, Wu MC | Applied physics letters | 19884988 | Appl Phys Lett | 2009 Sep 14 |
| Copolymeric nanofilm platform for controlled and localized therapeutic delivery. | Chow EK, Pierstorff E, Cheng G, Ho D | ACS nano | 19206545 | ACS Nano | 2008 Jan |
| Aptamer-based electrochemical biosensor for Botulinum neurotoxin. | Wei F, Ho CM | Analytical and bioanalytical chemistry | 19234874 | Anal Bioanal Chem | 2009 Apr |
| A unified platform for optoelectrowetting and optoelectronic tweezers. | Valley JK, Pei SN, Jamshidi A, Hsu HY, Wu MC | Lab on a chip | 21311817 | Lab Chip | 2011 Apr 7 |
| Synthesis of a gold nanoparticle dimer plasmonic resonator through two-phase-mediated functionalization. | Yim TJ, Wang Y, Zhang X | Nanotechnology | 20737026 | Nanotechnology | 2008 Oct 29 |
| Oxidative stress induces reactivation of Kaposi's sarcoma-associated herpesvirus and death of primary effusion lymphoma cells. | Li X, Feng J, Sun R | Journal of virology | 21068240 | J Virol | 2011 Jan |
| Photothermal nanoblade for large cargo delivery into mammalian cells. | Wu TH, Teslaa T, Kalim S, French CT, Moghadam S, Wall R, Miller JF, Witte ON, Teitell MA, Chiou PY | Analytical chemistry | 21247066 | Anal Chem | 2011 Feb 15 |
| Local plasticity of dendritic excitability can be autonomous of synaptic plasticity and regulated by activity-based phosphorylation of Kv4.2. | Labno A, Warrier A, Wang S, Zhang X | PloS one | 24404150 | PLoS One | 2014 |
| Single-cell mass cytometry for analysis of immune system functional states. | Bjornson ZB, Nolan GP, Fantl WJ | Current opinion in immunology | 23999316 | Curr Opin Immunol | 2013 Aug |
| Rapidly quantifying drug sensitivity of dispersed and clumped breast cancer cells by mass profiling. | Chun J, Zangle TA, Kolarova T, Finn RS, Teitell MA, Reed J | The Analyst | 23057068 | Analyst | 2012 Dec 7 |
| IMMUNOLOGY. An interactive reference framework for modeling a dynamic immune system. | Spitzer MH, Gherardini PF, Fragiadakis GK, Bhattacharya N, Yuan RT, Hotson AN, Finck R, Carmi Y, Zunder ER, Fantl WJ, Bendall SC, Engleman EG, Nolan GP | Science (New York, N.Y.) | 26160952 | Science | 2015 Jul 10 |
| Human polynucleotide phosphorylase: location matters. | Chen HW, Koehler CM, Teitell MA | Trends in cell biology | 17983748 | Trends Cell Biol | 2007 Dec |
| PNPASE regulates RNA import into mitochondria. | Wang G, Chen HW, Oktay Y, Zhang J, Allen EL, Smith GM, Fan KC, Hong JS, French SW, McCaffery JM, Lightowlers RN, Morse HC 3rd, Koehler CM, Teitell MA | Cell | 20691904 | Cell | 2010 Aug 6 |
| New developments in the induction and antiviral effectors of type I interferon. | Liu SY, Sanchez DJ, Cheng G | Current opinion in immunology | 21123041 | Curr Opin Immunol | 2011 Feb |
| Optoelectronic tweezers as a tool for parallel single-cell manipulation and stimulation. | Valley JK, Ohta AT, Hsan-Yin Hsu, Neale SL, Jamshidi A, Wu MC | IEEE transactions on biomedical circuits and systems | 20543904 | IEEE Trans Biomed Circuits Syst | 2009 Dec |
| Epigenetic silencing of Stk39 in B-cell lymphoma inhibits apoptosis from genotoxic stress. | Balatoni CE, Dawson DW, Suh J, Sherman MH, Sanders G, Hong JS, Frank MJ, Malone CS, Said JW, Teitell MA | The American journal of pathology | 19717643 | Am J Pathol | 2009 Oct |
| Photolithographic patterning of organosilane monolayer for generating large area two-dimensional B lymphocyte arrays. | Li N, Ho CM | Lab on a chip | 19023473 | Lab Chip | 2008 Dec |
| Time-resolved single-step protease activity quantification using nanoplasmonic resonator sensors. | Sun C, Su KH, Valentine J, Rosa-Bauza YT, Ellman JA, Elboudwarej O, Mukherjee B, Craik CS, Shuman MA, Chen FF, Zhang X | ACS nano | 20121209 | ACS Nano | 2010 Feb 23 |
| Regulation of cell differentiation by the DNA damage response. | Sherman MH, Bassing CH, Teitell MA | Trends in cell biology | 21354798 | Trends Cell Biol | 2011 May |
| Developing defined culture systems for human pluripotent stem cells. | Valamehr B, Tsutsui H, Ho CM, Wu H | Regenerative medicine | 21916597 | Regen Med | 2011 Sep |
| The convergence of bio, nano, and information technology: When Worlds Collide. | Ho CM, Chen JM | IEEE nanotechnology magazine | 20953308 | IEEE Nanotechnol Mag | 2008 Feb 15 |
| Live-cell mass profiling: an emerging approach in quantitative biophysics. | Zangle TA, Teitell MA | Nature methods | 25423019 | Nat Methods | 2014 Dec |
| Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus. | Sen N, Mukherjee G, Sen A, Bendall SC, Sung P, Nolan GP, Arvin AM | Cell reports | 25043183 | Cell Rep | 2014 Jul 24 |
| Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. | Bendall SC, Simonds EF, Qiu P, Amir el-AD, Krutzik PO, Finck R, Bruggner RV, Melamed R, Trejo A, Ornatsky OI, Balderas RS, Plevritis SK, Sachs K, Pe'er D, Tanner SD, Nolan GP | Science (New York, N.Y.) | 21551058 | Science | 2011 May 6 |
| Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade. | French CT, Toesca IJ, Wu TH, Teslaa T, Beaty SM, Wong W, Liu M, Schröder I, Chiou PY, Teitell MA, Miller JF | Proceedings of the National Academy of Sciences of the United States of America | 21730143 | Proc Natl Acad Sci U S A | 2011 Jul 19 |
| Cell kinase activity assay based on surface enhanced Raman spectroscopy. | Yue Z, Zhuang F, Kumar R, Wong I, Cronin SB, Liu YH | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy | 19299194 | Spectrochim Acta A Mol Biomol Spectrosc | 2009 Jul 15 |
| Integrative systems control approach for reactivating Kaposi's sarcoma-associated herpesvirus (KSHV) with combinatory drugs. | Sun CP, Usui T, Yu F, Al-Shyoukh I, Shamma J, Sun R, Ho CM | Integrative biology : quantitative biosciences from nano to macro | 19851479 | Integr Biol (Camb) | 2009 Jan |
| Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas. | Dawson DW, Hong JS, Shen RR, French SW, Troke JJ, Wu YZ, Chen SS, Gui D, Regelson M, Marahrens Y, Morse HC 3rd, Said J, Plass C, Teitell MA | Oncogene | 17260020 | Oncogene | 2007 Jun 21 |
| Dynamic manipulation and separation of individual semiconducting and metallic nanowires. | Jamshidi A, Pauzauskie PJ, Schuck PJ, Ohta AT, Chiou PY, Chou J, Yang P, Wu MC | Nature photonics | 19789729 | Nat Photonics | 2008 |
| Cell Separation by Non-Inertial Force Fields in Microfluidic Systems. | Tsutsui H, Ho CM | Mechanics research communications | 20046897 | Mech Res Commun | 2009 Jan 1 |
| Parallel single-cell light-induced electroporation and dielectrophoretic manipulation. | Valley JK, Neale S, Hsu HY, Ohta AT, Jamshidi A, Wu MC | Lab on a chip | 19495455 | Lab Chip | 2009 Jun 21 |
| Image patterned molecular delivery into live cells using gold particle coated substrates. | Wu TH, Kalim S, Callahan C, Teitell MA, Chiou PY | Optics express | 20173916 | Opt Express | 2010 Jan 18 |
| Minimal size of coffee ring structure. | Shen X, Ho CM, Wong TS | The journal of physical chemistry. B | 20353247 | J Phys Chem B | 2010 Apr 29 |
| Control of Kaposi's sarcoma-associated herpesvirus reactivation induced by multiple signals. | Yu F, Al-Shyoukh I, Feng J, Li X, Liao CW, Ho CM, Shamma JS, Sun R | PloS one | 21904595 | PLoS One | 2011 |
