Taking out a cancer’s co-dependency
July 13, 2011
Scientists at the Broad Institute and Massachusetts General Hospital (MGH) have discovered a novel compound that blocks a protective response to oxidative stress selectively in cancer cells but spares normal cells, with an effectiveness that surpassed a chemotherapy drug currently used to treat breast cancer.
Fountain of Youth? Worms Reveal New Clues About Long Life
May 12, 2011
Scientists in the Common Fund’s Interdisciplinary Research Consortium for Geroscience at the Buck Institute for Age Research have identified a class of molecules called N-acylethanolamines (NAEs) that alert worms when calorie intake is low, and trigger responses that slow aging and increase lifespan.
Colorful solution to extending lifespan
April 1, 2011
Researchers at the Common Fund’s Interdisciplinary Research Consortium for Geroscience have discovered that the laboratory dye Thioflavin T (ThT) extends median lifespan in roundworms by 60%.
Mouse Genetics Leads to New Clues for Human Psychiatric Disorders
March 10, 2011
In a paper available online March 10, 2011 in the journal Biological Psychiatry, researchers in the Common Fund’s Interdisciplinary Research program’s Consortium for Neuropsychiatric Phenomics report that they have identified several genes associated with poor impulse control in mice, and that these findings might be applicable to humans as well.
Regulation of Proteins Plays an Important Role in Aging
September 7, 2010
Dr. Gordon Lithgow and colleagues at the Buck Institute, one of nine interdisciplinary research consortia funded by the Common Fund, have uncovered cellular processes that play an important role in longevity and protection from environmental stress
Deciphering Fragile-X Associated Diseases
January 1, 2010
Dr. Paul Hagerman and colleagues at the Neurotherapeutics Research Institute at the University of California-Davis, one of nine Interdisciplinary Research Consortia funded by the Common Fund, are deciphering the molecular and cellular basis of a late onset disorder called Fragile-X associated tremor/ataxia syndrome, or FXTAS, in order to provide new avenues for early intervention which are desperately needed.