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Systemic Health Implications of the Leaky Barriers within the Oral-Gut-Brain Axis and its Pathways of Communication. Kim RY, Kuraji R, Kapila YL European Medical Journal (Chelmsford, England) 41404120 Eur Med J (Chelmsf) 2025 Mar https://www.ncbi.nlm.nih.gov/pubmed/41404120
Single cell transcriptomic analysis reveals dynamic cellular composition changes at acupuncture point BL23 (Shenshu) in low back pain. Zhao G, Wu X, Huang S, Huang S, Zhang G, Zhou X, Cao S, Lim HJ, Duhon MII, Li R, Boström KI, Li X Molecular pain 41312958 Mol Pain 2025 Jan-Dec https://www.ncbi.nlm.nih.gov/pubmed/41312958
The FDA's plan to phase out animal testing. Gerke S, Balamut J, Wagner JK Trends in biotechnology 41571550 Trends Biotechnol 2026 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/41571550
The Microbe Directory: a centralized database for biological interpretation of microbiome data. Sierra MA, Ryon K, Arikatla MR, Elshafey R, Bhaskar H, Proszynski J, Bhattacharya C, Shaaban H, Danko DC, Ambrose P, Spaulding SA, Zambrano MM, Consortium TMD, Mason CE Database : the journal of biological databases and curation 40996703 Database (Oxford) 2025 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/40996703
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew. Jones CW, Overbey EG, Lacombe J, Ecker AJ, Meydan C, Ryon K, Tierney B, Damle N, MacKay M, Afshin EE, Foox J, Park J, Nelson TM, Suhail Mohamad M, Byhaqui SGA, Aslam B, Tali UA, Nisa L, Menon PV, Patel CO, Khan SA, Ebert DJ, Everson A, Schubert MC, Ali NN, Sarma MS, Kim J, Houerbi N, Grigorev K, Garcia Medina JS, Summers AJ, Gu J, Altin JA, Fattahi A, Hirzallah MI, Wu JH, Stahn AC, Beheshti A, Klotz R, Ortiz V, Yu M, Patras L, Matei I, Lyden D, Melnick A, Banerjee N, Mullane S, Kleinman AS, Loesche M, Menon AS, Donoviel DB, Urquieta E, Mateus J, Sargsyan AE, Shelhamer M, Zenhausern F, Bershad EM, Basner M, Mason CE Nature 38862026 Nature 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38862026
Analysis of metagenomic data. Liu S, Rodriguez JS, Munteanu V, Ronkowski C, Sharma NK, Alser M, Andreace F, Blekhman R, Błaszczyk D, Chikhi R, Crandall KA, Della Libera K, Francis D, Frolova A, Gancz AS, Huntley NE, Jaiswal P, Kosciolek T, Łabaj PP, Łabaj W, Luan T, Mason C, Moustafa AM, Muralidharan HS, Mutlu O, Mansouri Ghiasi N, Rahnavard A, Sun F, Tian S, Tierney BT, Van Syoc E, Vicedomini R, Zackular JP, Zelikovsky A, Zielińska K, Ganda E, Davenport ER, Pop M, Koslicki D, Mangul S Nature reviews. Methods primers 40688383 Nat Rev Methods Primers 2025 https://www.ncbi.nlm.nih.gov/pubmed/40688383
The prototypic crAssphage is a linear phage-plasmid. Schmidtke DT, Hickey AS, Wirbel J, Lin JD, Liachko I, Sherlock G, Bhatt AS Cell host & microbe 40730160 Cell Host Microbe 2025 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/40730160
Astroimmunology: the effects of spaceflight and its associated stressors on the immune system. Winer DA, Du H, Kim J, Chang V, Burke M, Winer S, Costes SV, Frippiat JP, Sams C, Paul AM, Wu H, Ullrich O, Baatout S, Beheshti A, Mason CE, Choukér A, Crucian BE Nature reviews. Immunology 41102553 Nat Rev Immunol 2026 Mar https://www.ncbi.nlm.nih.gov/pubmed/41102553
Multi-Omics Profiling of Individuals Sustaining Extreme Physical Stressors. Sakharkar A, Chen R, LeRoy E, Nelson TM, Proszynski J, Kim J, Park J, Arikatla MR, Mathyk B, Mason CE Life (Basel, Switzerland) 41010319 Life (Basel) 2025 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/41010319
A second space age spanning omics, platforms and medicine across orbits. Mason CE, Green J, Adamopoulos KI, Afshin EE, Baechle JJ, Basner M, Bailey SM, Bielski L, Borg J, Borg J, Broddrick JT, Burke M, Caicedo A, Castañeda V, Chatterjee S, Chin CR, Church G, Costes SV, De Vlaminck I, Desai RI, Dhir R, Diaz JE, Etlin SM, Feinstein Z, Furman D, Garcia-Medina JS, Garrett-Bakelman F, Giacomello S, Gupta A, Hassanin A, Houerbi N, Irby I, Javorsky E, Jirak P, Jones CW, Kamal KY, Kangas BD, Karouia F, Kim J, Kim JH, Kleinman AS, Lam T, Lawler JM, Lee JA, Limoli CL, Lucaci A, MacKay M, McDonald JT, Melnick AM, Meydan C, Mieczkowski J, Muratani M, Najjar D, Othman MA, Overbey EG, Paar V, Park J, Paul AM, Perdyan A, Proszynski J, Reynolds RJ, Ronca AE, Rubins K, Ryon KA, Sanders LM, Glowe PS, Shevde Y, Schmidt MA, Scott RT, Shirah B, Sienkiewicz K, Sierra MA, Siew K, Theriot CA, Tierney BT, Venkateswaran K, Hirschberg JW, Walsh SB, Walter C, Winer DA, Yu M, Zea L, Mateus J, Beheshti A Nature 38862027 Nature 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38862027
CAMP: a modular metagenomics analysis system for integrated multistep data exploration. Mak L, Tierney B, Wei W, Ronkowski C, Toscan RB, Turhan B, Toomey M, Andrade-Martínez JS, Fu C, Lucaci AG, Solano AHB, Setubal JC, Henriksen JR, Zimmerman S, Kopbayeva M, Noyvert A, Iwan Z, Kar S, Nakazawa N, Meleshko D, Horyslavets D, Kantsypa V, Frolova A, Kahles A, Danko D, Elhaik E, Labaj P, Mangul S, International MetaSUB Consortium, Mason CE, Hajirasouliha I NAR genomics and bioinformatics 41551931 NAR Genom Bioinform 2026 Mar https://www.ncbi.nlm.nih.gov/pubmed/41551931
A robust benchmark for detecting low-frequency variants in the HG002 Genome In A Bottle NIST reference material. Daniels CA, Abdulkadir A, Cleveland MH, McDaniel JH, Jáspez D, Rubio-Rodríguez LA, Muñoz-Barrera A, Lorenzo-Salazar JM, Flores C, Yoo B, Sahraeian SME, Wang Y, Rossi M, Visvanath A, Murray L, Chen WT, Catreux S, Han J, Mehio R, Parnaby G, Carroll A, Chang PC, Shafin K, Cook D, Kolesnikov A, Brambrink L, Mootor MFE, Patel Y, Yamaguchi TN, Boutros PC, Sienkiewicz K, Foox J, Mason CE, Lajoie BR, Ruiz-Perez CA, Kruglyak S, Zook JM, Olson ND bioRxiv : the preprint server for biology 39677813 bioRxiv 2024 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/39677813
To boldly go where no microRNAs have gone before: spaceflight impact on risk for small-for-gestational-age infants. Corti G, Kim J, Enguita FJ, Guarnieri JW, Grossman LI, Costes SV, Fuentealba M, Scott RT, Magrini A, Sanders LM, Singh K, Sen CK, Juran CM, Paul AM, Furman D, Calleja-Agius J, Mason CE, Galeano D, Bottini M, Beheshti A Communications biology 39369042 Commun Biol 2024 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/39369042
Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair. McDaniel JH, Patel V, Olson ND, He HJ, He Z, Cole KD, Gooden AA, Schmitt A, Sikkink K, Sedlazeck FJ, Doddapaneni H, Jhangiani SN, Muzny DM, Gingras MC, Mehta H, Behera S, Paulin LF, Hastie AR, Yu HC, Weigman V, Rojas A, Kennedy K, Remington J, Salas-González I, Sudkamp M, Wiseman K, Lajoie BR, Levy S, Jain M, Akeson S, Narzisi G, Steinsnyder Z, Reeves C, Shelton J, Kingan SB, Lambert C, Baybayan P, Wenger AM, McLaughlin IJ, Adamson A, Kingsley C, Wescott M, Kim Y, Paten B, Park J, Violich I, Miga KH, Gardner J, McNulty B, Rosen GL, McCoy R, Brundu F, Sayyari E, Scheffler K, Truong S, Catreux S, Hannah LC, Lipson D, Benjamin H, Iremadze N, Soifer I, Krieger G, Eacker S, Wood M, Cross E, Husar G, Gross S, Vernich M, Kolmogorov M, Ahmad T, Keskus AG, Bryant A, Thibaud-Nissen F, Trow J, Proszynski J, Hirschberg JW, Ryon K, Mason CE, Bhakta MS, Sanborn JZ, Munding EM, Wagner J, Xiao C, Liss AS, Zook JM Scientific data 40670386 Sci Data 2025 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/40670386
Long-read metagenomics reveals phage dynamics in the human gut microbiome. Wirbel J, Hickey AS, Chang D, Enright NJ, Dvorak M, Chanin RB, Schmidtke DT, Bhatt AS Nature 41299176 Nature 2026 Jan https://www.ncbi.nlm.nih.gov/pubmed/41299176
Co-evolved Partners of Immunity: A Trait-Based Map of Human Keystone Organisms. Asiaee A, Mallal N, Phillips E, Mallal S bioRxiv : the preprint server for biology 41502936 bioRxiv 2026 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/41502936
Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function. Liu Y, Gu X, Li Y, Wang F, Vyas CM, Peng C, Dong D, Li Y, Zhang Y, Zhang Y, Zeleznik OA, Kang JH, Wang M, Hu FB, Willett WC, Okereke OI, Eliassen AH, Kraft P, Stampfer MJ, Wang DD Nature medicine 40855194 Nat Med 2025 Nov https://www.ncbi.nlm.nih.gov/pubmed/40855194
Dynamics of gut bacteriophage in diversity outbred mice studied over lifespan and during extreme caloric restriction. Merenstein C, Litichevskiy L, Thaiss C, Collman RG, Bushman FD Microbiome 41772715 Microbiome 2026 Mar 3 https://www.ncbi.nlm.nih.gov/pubmed/41772715
Optimizing methods for virome analysis based on studies of a synthetic viral community. Duan J, Marques AD, Hogenauer M, Hwang Y, Zhang Y, Timperman A, Higgins S, Wilson NG, Fitts EA, Lim HK, Bittinger K, Moustafa AM, Collman RG, Bushman FD bioRxiv : the preprint server for biology 41278782 bioRxiv 2025 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/41278782
DNA extraction and virome processing methods strongly influence recovered human gut viral community characteristics. Hillary LS, Knotts TA, Adams SH, Ali MR, Olm MR, Emerson JB bioRxiv : the preprint server for biology 41394752 bioRxiv 2025 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/41394752
A genomic atlas of the human gut virome elucidates genetic factors shaping host interactions. Camargo AP, Baltoumas FA, Ndela EO, Fiamenghi MB, Merrill BD, Carter MM, Pinto Y, Chakraborty M, Andreeva A, Ghiotto G, Shaw J, Proal AD, Sonnenburg JL, Bhatt AS, Roux S, Pavlopoulos GA, Nayfach S, Kyrpides NC bioRxiv : the preprint server for biology 41279291 bioRxiv 2025 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/41279291
Meta-virus resource (MetaVR): expanding the frontiers of viral diversity with 24 million uncultivated virus genomes. Fiamenghi MB, Camargo AP, Chasapi IN, Baltoumas FA, Roux S, Egorov AA, Aplakidou E, Ndela EO, Vasquez YM, Chen IA, Palaniappan K, Reddy TBK, Mukherjee S, Ivanova NN, Schulz F, Woyke T, Eloe-Fadrosh EA, Pavlopoulos GA, Kyrpides NC Nucleic acids research 41312645 Nucleic Acids Res 2026 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/41312645
Protocol for large-scale, high-yield, high-purity extracellular vesicle purification from human plasma. Zanganeh S, Arias GF, Cone AS, Yuan R, Dittmer DP STAR protocols 41818236 STAR Protoc 2026 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/41818236
Viral Load Measurements for Kaposi Sarcoma Herpesvirus (KSHV/HHV8): Review and an Updated Assay. Cano P, Seltzer T, Seltzer J, Peng A, Landis J, Pluta L, Dittmer DP Journal of medical virology 39648698 J Med Virol 2024 Dec https://www.ncbi.nlm.nih.gov/pubmed/39648698
Dynamics of Bacterial and Viral Transmission in Experimental Microbiota Transplantation. Weagley JS, Cárdenas LAC, Romani A, Sullender ME, Aggarwal S, Makimaa H, Hogarty MP, Rodgers R, Kennedy EA, Foster L, Schriefer LA, Baldridge MT bioRxiv : the preprint server for biology 39868290 bioRxiv 2025 May 7 https://www.ncbi.nlm.nih.gov/pubmed/39868290
Single cell viral tagging of Faecalibacterium prausnitzii reveals rare bacteriophages omitted by other techniques. Campbell DE, Wu X, Hall LR, Lawrence D, Molleston JM, Schriefer LA, Droit L, Weagley JS, Olson BS, Rimmer J, Parkes M, Handley SA, Baldridge MT Gut microbes 40754853 Gut Microbes 2025 Dec https://www.ncbi.nlm.nih.gov/pubmed/40754853
Differential microbial community assembly following co-housing versus microbiota transplant. Weagley JS, Chica Cárdenas LA, Romani A, Sullender ME, Aggarwal S, Makimaa H, Hogarty MP, Rodgers R, Kennedy EA, Foster L, Schriefer LA, Baldridge MT The ISME journal 41247324 ISME J 2025 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/41247324
Clec12a controls colitis by tempering inflammation and restricting expansion of specific commensals. Chiaro TR, Greenewood M, Bauer KM, Ost KS, Stephen-Victor E, Murphy M, Weis AM, Nelson MC, Hill JH, Bell R, Voth W, Jackson T, Klag KA, O'Connell RM, Zac Stephens W, Round JL Cell host & microbe 39788099 Cell Host Microbe 2025 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/39788099
Dietary fat disrupts a commensal-host lipid network that promotes metabolic health. Klag K, Ott D, Tippetts TS, Nicolson RJ, Tatum SM, Bauer KM, Stephen-Victor E, Weis AM, Bell R, Weagley J, Maschek JA, Vu DL, Heaver S, Ley R, O'Connell R, Holland WL, Summers SA, Stephens WZ, Round JL Cell metabolism 41197631 Cell Metab 2026 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/41197631
Population-scale sequencing resolves correlates and determinants of latent Epstein-Barr Virus infection. Nyeo SS, Cumming EM, Burren OS, Pagadala MS, Gutierrez JC, Ali TA, Kida LC, Chen Y, Hu F, Hollis B, Fabre M, MacArthur S, Wang Q, Ludwig LS, Dey KK, Petrovski S, Dhindsa RS, Lareau CA bioRxiv : the preprint server for biology 40791404 bioRxiv 2025 Jul 18 https://www.ncbi.nlm.nih.gov/pubmed/40791404
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing. Abay T, Stickels RR, Takizawa MT, Nalbant BN, Hsieh YH, Hwang S, Snopkowski C, Yu KKH, Abou-Mrad Z, Tabar V, Howitt BE, Ludwig LS, Chaligné R, Satpathy AT, Lareau CA Nature genetics 39779958 Nat Genet 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39779958
Clonal lineage tracing of innate immune cells in human cancer. Liu V, Sandor K, Yan PK, Miao M, Yin Y, Stickels RR, Chen AY, Hiam-Galvez K, Gutierrez J, Zhang W, Sajjath SM, Valbuena R, Wang S, Dániel B, Ludwig LS, Howitt BE, Lareau C, Satpathy AT bioRxiv : the preprint server for biology 40777278 bioRxiv 2025 Jul 21 https://www.ncbi.nlm.nih.gov/pubmed/40777278
Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer. Boscenco S, Tait-Mulder J, Kim M, Tang C, Park T, McNulty F, Lilla S, Zanivan S, Huerta-Uribe A, Nalbant B, Zucker M, Sumpton D, Monteuuis G, Jackson CB, Wei W, Chinnery PF, Chaligne R, Lareau CA, Reznik E, Gammage PA Nature genetics 41184543 Nat Genet 2025 Nov https://www.ncbi.nlm.nih.gov/pubmed/41184543
CAR-engineered lymphocyte persistence is governed by a FAS ligand-FAS autoregulatory circuit. Yi F, Cohen T, Zimmerman N, Dündar F, Zumbo P, Eltilib R, Brophy EJ, Arkin H, Feucht J, Gormally MV, Hackett CS, Kropp KN, Etxeberria I, Chandran SS, Zhao Z, Cai W, Daniyan AF, Park JH, Lareau CA, Hsu KC, Sadelain M, Betel D, Klebanoff CA Nature cancer 40696154 Nat Cancer 2025 Oct https://www.ncbi.nlm.nih.gov/pubmed/40696154
Cell type-specific purifying selection of synonymous mitochondrial DNA variation. Lareau CA, Maschmeyer P, Yin Y, Gutierrez JC, Dhindsa RS, Gribling-Burrer AS, Zielinski S, Hsieh YH, Nitsch L, Dimitrova V, Nalbant B, Buquicchio FA, Abay T, Stickels RR, Ulirsch JC, Yan P, Wang F, Miao Z, Sandor K, Daniel B, Liu V, Mendez PL, Knaus P, Meyer M, Greenleaf WJ, Kundaje A, Smyth RP, Munschauer M, Ludwig LS, Satpathy AT Proceedings of the National Academy of Sciences of the United States of America 40705423 Proc Natl Acad Sci U S A 2025 Jul 29 https://www.ncbi.nlm.nih.gov/pubmed/40705423
Population-scale sequencing resolves determinants of persistent EBV DNA. Nyeo SS, Cumming EM, Burren OS, Pagadala MS, Gutierrez JC, Ali TA, Kida LC, Chen Y, Chu H, Hu F, Zou XZ, Hollis B, Fabre MA, MacArthur S, Wang Q, Ludwig LS, Dey KK, Petrovski S, Dhindsa RS, Lareau CA Nature 41606327 Nature 2026 Feb https://www.ncbi.nlm.nih.gov/pubmed/41606327

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