The HCS Collaboratory Solicits a New Round of Pragmatic Clinical Trial Demonstration Projects. The HCS Collaboratory has issued a funding opportunity announcement for a new round of demonstration projects that include an efficient, large-scale pragmatic clinical trial. Multiple NIH Institutes and Centers have signed on to participate. Applications are due June 2, 2017. Read the Funding Opportunity Announcement. A technical assistance webinar for potential applicants will be held January 24, 2017 at 1:30 PM, ET to review the purpose and objectives of the Funding Opportunity Announcement and to address questions from the community. View information on the webinar.
Lumbar Imaging with Reporting of Epidemiology (LIRE) Trial Completes Enrollment. LIRE is a pragmatic clinical trial supported by the Collaboratory. It tests the effectiveness of giving doctors normal spine image reports to use as a comparison when they are trying to diagnose patients with lower back pain. In September 2016, LIRE completed enrollment of trial participants. Congratulations to the LIRE team on this important milestone! Learn more about the LIRE trial.
ICD Pieces Pragmatic Clinical Trial Begins Enrollment. ICD Pieces is a pragmatic clinical trial demonstration project supported by the Collaboratory. The trial will implement a new technology platform (Pieces) to enable use of electronic health record data to improve care for patients with chronic kidney disease and other associated conditions. Congratulations to the ICD Pieces Team on this important milestone! Learn more about the ICD Pieces trial.
Collaboratory's Regulatory Ethics/Core Publishes Study on Doctors' viewpoints on Pragmatic Clinical Trials. The Collaboratory's Regulatory/Ethics Core found in a recent study that while doctors are generally willing to participate in pragmatic clinical trials, “their support is predicated on several factors including expected benefits, minimization of time and workflow burdens, and physician engagement.” Read the article abstract.
Protocol Published for the Trauma Survivors and Support (TSOS) Trial. Congratulations to the study team for the TSOS trial, who recently published the protocol for their trial in Implementation Science! The TSOS trial is intended to improve care for patients with posttraumatic stress disorder and other associated conditions. Read the article abstract. Learn more about the TSOS trial.