Scientific Meetings

• HCS Research Collaboratory Weekly Grand Rounds
  The NIH HCS Research Collaboratory hosts Pragmatic Clinical Trial Grand Rounds webinars on challenges and opportunities in conducting clinical trials at the site of medical care. Grand Rounds are a collaboration with the National Patient-Centered Clinical Research Network (PCORnet) and participants of the Clinical and Translational Science Awards (CTSA) program. View archived files or upcoming Grand Rounds presentations. Follow the conversation on Twitter at: @PCTGrandRounds.
• Pragmatic Clinical Trials - Design & Analysis of Embedded Pragmatic Clinical Trials
  May 2, 2019
  Bethesda, MD
  Agenda, Registration, and Meeting Information
  Archived Videocast of the Meeting
• Pragmatic Clinical Trials - Embedded Pragmatic Clinical Trials of Therapeutic A vs. B Interventions
  May 16, 2018
  Bethesda, MD
  Agenda, Registration, and Meeting Information
  Archived Videocast of the Meeting
• Pragmatic Clinical Trials - Unique Opportunities for Disseminating, Implementing, & Sustaining Evidence-Based Practices into Care Workshop
  May 24, 2017
  Bethesda, MD
  Agenda and Meeting Information
  Archived Videocast of the Meeting
• Ethical & Regulatory Issues of Pragmatic Clinical Trials Workshop
  May 10, 2016
  Agenda and Meeting Information
  Archived Videocast of the Meeting
  Meeting Materials and Slides
  NCCIH Research Blog post about the meeting
• HCS Research Collaboratory Steering Committee Meeting
  May 9-10, 2016
  Bethesda, MD
• HCS Research Collaboratory Steering Committee Meeting
  April 20-21, 2015
  Bethesda, MD
• HCS Research Collaboratory Steering Committee Meeting
  August 19-20, 2014
  Bethesda, MD
• HCS Research Collaboratory Steering Committee Meeting
  February 24-25, 2014
  Bethesda, MD

Early Program Meetings

Protection of Human Subjects HHS Meeting, August 2013
The Department of Health and Human Services (HHS) held a public meeting to seek input and comments on how certain provisions of the HHS requirements related to the protection of human subjects should be applied to research studying one or more interventions which are used as standard of care treatment in the non-research context.   HHS specifically requested input regarding how an institutional review board (IRB) should assess the risks of research involving randomization to one or more treatments within the standard of care for particular interventions, and what reasonably foreseeable risks of the research should be disclosed to research subjects in the informed consent process.  The public meeting took place August 28, 2013 from 9:00 am to 5:00 pm. Download transcripts of the meeting.

Coordinating Center-Organized Meeting, July 2013
The NIH HCS Collaboratory hosted a “Cluster Randomized Trials: Ethical, Regulatory and Practical Issues” workshop on July 29, 2013.   The objectives of the workshop were:

• To describe the ethical issues related to cluster randomized trials
• To determine the extent to which existing guidelines and policies related to cluster randomized trials are appropriate for research conducted in the United States or funded by the US government
• To capture the findings in a white paper and/or peer-reviewed publication.

Representatives from a broad cross-section of the clinical trial enterprise including regulators, government sponsors of clinical research, academia, industry, patient advocates, clinical investigators, and other interested parties were in attendance.

Archived Meetings

• Technical Assistance Videocast for RFA-RM-11-021: NIH Health Care Systems Research Collaboratory - Coordinating Center (U54) (NOT-RM-12-012)
• Technical Assistance Videocast for RFA-RM-12-002: NIH Health Care Systems Research Collaboratory - Pragmatic Clinical Trials Demonstration Projects (UH2/UH3) (NOT-RM-12-013)
• NIH Workshop on Enhancing Collaboration with HMORN Research Organizations - March 15, 2010, NIH Main Campus, Bethesda, MD

Archived Activities

• NIH Sought Input on Leveraging Existing Health Data and Linked to Biospecimen Repositories for Epidemiology Research Read the Request for Information (RFI)