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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Authors Journal PubMedID Publication Date
Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity. Peterson, Kevin A; Khalouei, Sam; Hanafi, Nour; Wood, Joshua A; Lanza, Denise G; Lintott, Lauri G; Willis, Brandon J; Seavitt, John R; Braun, Robert E; Dickinson, Mary E; White, Jacqueline K; Lloyd, K C Kent; Heaney, Jason D; Murray, Stephen A; Ramani, Arun; Nutter, Lauryl M J Communications biology 37301944 2023 Jun 10
Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice. Oestereicher, Manuela A; Wotton, Janine M; Ayabe, Shinya; Bou About, Ghina; Cheng, Tsz Kwan; Choi, Jae-Hoon; Clary, Dave; Dew, Emily M; Elfertak, Lahcen; Guimond, Alain; Haseli Mashhadi, Hamed; Heaney, Jason D; Kelsey, Lois; Keskivali-Bond, Piia; Lopez Gomez, Federico; Marschall, Susan; McFarland, Michael; Meziane, Hamid; Munoz Fuentes, Violeta; Nam, Ki-Hoan; Nichtová, Zuzana; Pimm, Dale; Bower, Lynette; Prochazka, Jan; Rozman, Jan; Santos, Luis; Stewart, Michelle; Tanaka, Nobuhiko; Ward, Christopher S; Willett, Amelia M E; Wilson, Robert; Braun, Robert E; Dickinson, Mary E; Flenniken, Ann M; Herault, Yann; Lloyd, K C Kent; Mallon, Ann-Marie; McKerlie, Colin; Murray, Stephen A; Nutter, Lauryl M J; Sedlacek, Radislav; Seong, Je Kyung; Sorg, Tania; Tamura, Masaru; Wells, Sara; Schneltzer, Elida; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; White, Jacqueline K; Spielmann, Nadine Mammalian genome : official journal of the International Mammalian Genome Society 37294348 2023 Jun
Topologically associating domain boundaries are required for normal genome function. Rajderkar, Sudha; Barozzi, Iros; Zhu, Yiwen; Hu, Rong; Zhang, Yanxiao; Li, Bin; Alcaina Caro, Ana; Fukuda-Yuzawa, Yoko; Kelman, Guy; Akeza, Adyam; Blow, Matthew J; Pham, Quan; Harrington, Anne N; Godoy, Janeth; Meky, Eman M; von Maydell, Kianna; Hunter, Riana D; Akiyama, Jennifer A; Novak, Catherine S; Plajzer-Frick, Ingrid; Afzal, Veena; Tran, Stella; Lopez-Rios, Javier; Talkowski, Michael E; Lloyd, K C Kent; Ren, Bing; Dickel, Diane E; Visel, Axel; Pennacchio, Len A Communications biology 37081156 2023 Apr 20
Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a NO-CCL2-CCR2 pathway. Ye, Qi; Jo, Juyeon; Wang, Chih-Yen; Oh, Heavin; Choy, Tiffany J; Kim, Kyoungin; Dâ Alessandro, Angelo; Reshetnyak, Yana K; Jung, Sung Yun; Chen, Zheng; Marrelli, Sean P; Lee, Hyun Kyoung bioRxiv : the preprint server for biology 37066295 2023 Apr 03
Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state. Yu, Wangie; Chen, Yunyun; Putluri, Nagireddy; Osman, Abdullah; Coarfa, Cristian; Putluri, Vasanta; Kamal, Abu H M; Asmussen, Jennifer Kay; Katsonis, Panagiotis; Myers, Jeffrey N; Lai, Stephen Y; Lu, Wuhao; Stephan, Clifford C; Powell, Reid T; Johnson, Faye M; Skinner, Heath D; Kazi, Jawad; Ahmed, Kazi Mokim; Hu, Linghao; Threet, Addison; Meyer, Matthew D; Bankson, James A; Wang, Tony; Davis, Jack; Parker, Kirby R; Harris, Madison A; Baek, Mokryun L; Echeverria, Gloria V; Qi, Xiaoli; Wang, Jin; Frederick, Andy I; Walsh, Alex J; Lichtarge, Olivier; Frederick, Mitchell J; Sandulache, Vlad C British journal of cancer 37012319 2023 Jun
The role of Limch1 alternative splicing in skeletal muscle function. Penna, Matthew S; Hu, Rong-Chi; Rodney, George G; Cooper, Thomas A Life science alliance 36977593 2023 Jun
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation. Elliott, Kelsey H; Balchand, Sai K; Bonatto Paese, Christian Louis; Chang, Ching-Fang; Yang, Yanfen; Brown, Kari M; Rasicci, Daniel T; He, Hao; Thorner, Konrad; Chaturvedi, Praneet; Murray, Stephen A; Chen, Jing; Porollo, Aleksey; Peterson, Kevin A; Brugmann, Samantha A Development (Cambridge, England) 36971348 2023 Apr 15
Essential genes: a cross-species perspective. Cacheiro, Pilar; Smedley, Damian Mammalian genome : official journal of the International Mammalian Genome Society 36897351 2023 Mar 10
Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease. Jones, Kathryn M; Mangin, Elise N; Reynolds, Corey L; Villanueva, Liliana E; Cruz, Julio Vladimir; Versteeg, Leroy; Keegan, Brian; Kendricks, April; Pollet, Jeroen; Gusovsky, Fabian; Bottazzi, Maria Elena; Hotez, Peter J Frontiers in cellular and infection microbiology 36844399 2023
Knockout mice are an important tool for human monogenic heart disease studies. Cacheiro, Pilar; Spielmann, Nadine; Mashhadi, Hamed Haseli; Fuchs, Helmut; Gailus-Durner, Valerie; Smedley, Damian; de Angelis, Martin Hrabĕ Disease models & mechanisms 36825469 2023 May 01
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development. Chee, Justine M; Lanoue, Louise; Clary, Dave; Higgins, Kendall; Bower, Lynette; Flenniken, Ann; Guo, Ruolin; Adams, David J; Bosch, Fatima; Braun, Robert E; Brown, Steve D M; Chin, H-J Genie; Dickinson, Mary E; Hsu, Chih-Wei; Dobbie, Michael; Gao, Xiang; Galande, Sanjeev; Grobler, Anne; Heaney, Jason D; Herault, Yann; de Angelis, Martin Hrabe; Mammano, Fabio; Nutter, Lauryl M J; Parkinson, Helen; Qin, Chuan; Shiroishi, Toshi; Sedlacek, Radislav; Seong, J-K; Xu, Ying; International Mouse Phenotyping Consortium; Brooks, Brian; McKerlie, Colin; Lloyd, K C Kent; Westerberg, Henrik; Moshiri, Ala BMC biology 36737727 2023 Feb 03
A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis. Wang, Yuqing; Zhu, Duolong; Ortiz-Velez, Laura C; Perry, Jacob L; Pennington, Michael W; Hyser, Joseph M; Britton, Robert A; Beeton, Christine Proceedings of the National Academy of Sciences of the United States of America 36595694 2023 Jan 10
Three-dimensional microCT imaging of mouse heart development from early post-implantation to late fetal stages. Li-Villarreal, Nanbing; Rasmussen, Tara L; Christiansen, Audrey E; Dickinson, Mary E; Hsu, Chih-Wei Mammalian genome : official journal of the International Mammalian Genome Society 36595063 2023 Jan 03
Dysregulated systemic metabolism in a Down syndrome mouse model. Sarver, Dylan C; Xu, Cheng; Velez, Leandro M; Aja, Susan; Jaffe, Andrew E; Seldin, Marcus M; Reeves, Roger H; Wong, G William Molecular metabolism 36587842 2023 Feb
A novel model of gestational diabetes: Acute high fat high sugar diet results in insulin resistance and beta cell dysfunction during pregnancy in mice. Mishra, Akansha; Ruano, Simone Hernandez; Saha, Pradip K; Pennington, Kathleen A PloS one 36520818 2022
Sex differences in allometry for phenotypic traits in mice indicate that females are not scaled males. Wilson, Laura A B; Zajitschek, Susanne R K; Lagisz, Malgorzata; Mason, Jeremy; Haselimashhadi, Hamed; Nakagawa, Shinichi Nature communications 36509767 2022 Dec 12
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes. Higgins, Kendall; Moore, Bret A; Berberovic, Zorana; Adissu, Hibret A; Eskandarian, Mohammad; Flenniken, Ann M; Shao, Andy; Imai, Denise M; Clary, Dave; Lanoue, Louise; Newbigging, Susan; Nutter, Lauryl M J; Adams, David J; Bosch, Fatima; Braun, Robert E; Brown, Steve D M; Dickinson, Mary E; Dobbie, Michael; Flicek, Paul; Gao, Xiang; Galande, Sanjeev; Grobler, Anne; Heaney, Jason D; Herault, Yann; de Angelis, Martin Hrabe; Chin, Hsian-Jean Genie; Mammano, Fabio; Qin, Chuan; Shiroishi, Toshihiko; Sedlacek, Radislav; Seong, J-K; Xu, Ying; IMPC Consortium; Lloyd, K C Kent; McKerlie, Colin; Moshiri, Ala Scientific reports 36456625 2022 Dec 01
Neuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina. Jiang, Danye; Burger, Courtney A; Akhanov, Viktor; Liang, Justine H; Mackin, Robert D; Albrecht, Nicholas E; Andrade, Pilar; Schafer, Dorothy P; Samuel, Melanie A Immunity 36379210 2022 Dec 13
The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource. Sollis, Elliot; Mosaku, Abayomi; Abid, Ala; Buniello, Annalisa; Cerezo, Maria; Gil, Laurent; Groza, Tudor; Güneş, Osman; Hall, Peggy; Hayhurst, James; Ibrahim, Arwa; Ji, Yue; John, Sajo; Lewis, Elizabeth; MacArthur, Jacqueline A L; McMahon, Aoife; Osumi-Sutherland, David; Panoutsopoulou, Kalliope; Pendlington, Zoë; Ramachandran, Santhi; Stefancsik, Ray; Stewart, Jonathan; Whetzel, Patricia; Wilson, Robert; Hindorff, Lucia; Cunningham, Fiona; Lambert, Samuel A; Inouye, Michael; Parkinson, Helen; Harris, Laura W Nucleic acids research 36350656 2022 Nov 09
The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease. Groza, Tudor; Gomez, Federico Lopez; Mashhadi, Hamed Haseli; Muñoz-Fuentes, Violeta; Gunes, Osman; Wilson, Robert; Cacheiro, Pilar; Frost, Anthony; Keskivali-Bond, Piia; Vardal, Bora; McCoy, Aaron; Cheng, Tsz Kwan; Santos, Luis; Wells, Sara; Smedley, Damian; Mallon, Ann-Marie; Parkinson, Helen Nucleic acids research 36305825 2022 Oct 28
Baat Gene Knockout Alters Post-Natal Development, the Gut Microbiome, and Reveals Unusual Bile Acids in Mice. Neugebauer, Kerri A; Okros, Maxwell; Guzior, Douglas V; Feiner, Jeremiah; Chargo, Nicholas J; Rzepka, Madison; Schilmiller, Anthony L; O'Reilly, Sandra; Jones, A Daniel; Watson, Victoria E; Luyendyk, James P; McCabe, Laura R; Quinn, Robert A Journal of lipid research 36243101 2022 Dec
Mendelian gene identification through mouse embryo viability screening. Cacheiro, Pilar; Westerberg, Carl Henrik; Mager, Jesse; Dickinson, Mary E; Nutter, Lauryl M J; Muñoz-Fuentes, Violeta; Hsu, Chih-Wei; Van den Veyver, Ignatia B; Flenniken, Ann M; McKerlie, Colin; Murray, Stephen A; Teboul, Lydia; Heaney, Jason D; Lloyd, K C Kent; Lanoue, Louise; Braun, Robert E; White, Jacqueline K; Creighton, Amie K; Laurin, Valerie; Guo, Ruolin; Qu, Dawei; Wells, Sara; Cleak, James; Bunton-Stasyshyn, Rosie; Stewart, Michelle; Harrisson, Jackie; Mason, Jeremy; Haseli Mashhadi, Hamed; Parkinson, Helen; Mallon, Ann-Marie; International Mouse Phenotyping Consortium; Genomics England Research Consortium; Smedley, Damian Genome medicine 36229886 2022 Oct 13
Promoting validation and cross-phylogenetic integration in model organism research. Cheng, Keith C; Burdine, Rebecca D; Dickinson, Mary E; Ekker, Stephen C; Lin, Alex Y; Lloyd, K C Kent; Lutz, Cathleen M; MacRae, Calum A; Morrison, John H; O'Connor, David H; Postlethwait, John H; Rogers, Crystal D; Sanchez, Susan; Simpson, Julie H; Talbot, William S; Wallace, Douglas C; Weimer, Jill M; Bellen, Hugo J Disease models & mechanisms 36125045 2022 09 01
Clinical exome sequencing uncovers a high frequency of Mendelian disorders in infants with stroke: A retrospective analysis. Kumar, Runjun D; Meng, Linyan; Liu, Pengfei; Miyake, Christina Y; Worley, Kim C; Bi, Weimin; Lalani, Seema R American journal of medical genetics. Part A 36065636 2022 Sep 06
Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects. Liang, Justine H; Alevy, Jonathan; Akhanov, Viktor; Seo, Ryan; Massey, Cory A; Jiang, Danye; Zhou, Joy; Sillitoe, Roy V; Noebels, Jeffrey L; Samuel, Melanie A Disease models & mechanisms 35972048 2022 09 01
Multivariate phenotype analysis enables genome-wide inference of mammalian gene function. Nicholson, George; Morgan, Hugh; Ganjgahi, Habib; Brown, Steve D M; Mallon, Ann-Marie; Holmes, Chris PLoS biology 35944064 2022 Aug
Phenotype-aware prioritisation of rare Mendelian disease variants. Kelly, Catherine; Szabo, Anita; Pontikos, Nikolas; Arno, Gavin; Robinson, Peter N; Jacobsen, Jules O B; Smedley, Damian; Cipriani, Valentina Trends in genetics : TIG 35934592 2022 Dec
Arap1 loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death. Shao, Andy; Lopez, Antonio Jacobo; Chen, JiaJia; Tham, Addy; Javier, Seanne; Quiroz, Alejandra; Frick, Sonia; Levine, Edward M; Lloyd, K C Kent; Leonard, Brian C; Murphy, Christopher J; Glaser, Thomas M; Moshiri, Ala Disease models & mechanisms 35758026 2022 Jul 01
Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer. Pulliam, Thomas L; Awad, Dominik; Han, Jenny J; Murray, Mollianne M; Ackroyd, Jeffrey J; Goli, Pavithr; Oakhill, Jonathan S; Scott, John W; Ittmann, Michael M; Frigo, Daniel E Cells 35741020 2022 06 10
Preventing Cholesterol-Induced Perk (Protein Kinase RNA-Like Endoplasmic Reticulum Kinase) Signaling in Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation. Chattopadhyay, Abhijnan; Guan, Pujun; Majumder, Suravi; Kaw, Kaveeta; Zhou, Zhen; Zhang, Chen; Prakash, Siddharth K; Kaw, Anita; Buja, L Maximillian; Kwartler, Callie S; Milewicz, Dianna M Arteriosclerosis, thrombosis, and vascular biology 35708026 2022 08
The GA4GH Phenopacket schema defines a computable representation of clinical data. Jacobsen, Julius O B; Baudis, Michael; Baynam, Gareth S; Beckmann, Jacques S; Beltran, Sergi; Buske, Orion J; Callahan, Tiffany J; Chute, Christopher G; Courtot, Mélanie; Danis, Daniel; Elemento, Olivier; Essenwanger, Andrea; Freimuth, Robert R; Gargano, Michael A; Groza, Tudor; Hamosh, Ada; Harris, Nomi L; Kaliyaperumal, Rajaram; Lloyd, Kevin C Kent; Khalifa, Aly; Krawitz, Peter M; Köhler, Sebastian; Laraway, Brian J; Lehväslaiho, Heikki; Matalonga, Leslie; McMurry, Julie A; Metke-Jimenez, Alejandro; Mungall, Christopher J; Munoz-Torres, Monica C; Ogishima, Soichi; Papakonstantinou, Anastasios; Piscia, Davide; Pontikos, Nikolas; Queralt-Rosinach, Núria; Roos, Marco; Sass, Julian; Schofield, Paul N; Seelow, Dominik; Siapos, Anastasios; Smedley, Damian; Smith, Lindsay D; Steinhaus, Robin; Sundaramurthi, Jagadish Chandrabose; Swietlik, Emilia M; Thun, Sylvia; Vasilevsky, Nicole A; Wagner, Alex H; Warner, Jeremy L; Weiland, Claus; GAGH Phenopacket Modeling Consortium; Haendel, Melissa A; Robinson, Peter N Nature biotechnology 35705716 2022 Jun
MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses. Devine, Jay; Vidal-García, Marta; Liu, Wei; Neves, Amanda; Lo Vercio, Lucas D; Green, Rebecca M; Richbourg, Heather A; Marchini, Marta; Unger, Colton M; Nickle, Audrey C; Radford, Bethany; Young, Nathan M; Gonzalez, Paula N; Schuler, Robert E; Bugacov, Alejandro; Rolian, Campbell; Percival, Christopher J; Williams, Trevor; Niswander, Lee; Calof, Anne L; Lander, Arthur D; Visel, Axel; Jirik, Frank R; Cheverud, James M; Klein, Ophir D; Birnbaum, Ramon Y; Merrill, Amy E; Ackermann, Rebecca R; Graf, Daniel; Hemberger, Myriam; Dean, Wendy; Forkert, Nils D; Murray, Stephen A; Westerberg, Henrik; Marcucio, Ralph S; Hallgrímsson, Benedikt Scientific data 35614082 2022 May 25
Evaluation of phenotype-driven gene prioritization methods for Mendelian diseases. Jacobsen, Julius O B; Kelly, Catherine; Cipriani, Valentina; Robinson, Peter N; Smedley, Damian Briefings in bioinformatics 35595299 2022 09 20
Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism. Stork, Brittany A; Dean, Adam; Ortiz, Andrea R; Saha, Pradip; Putluri, Nagireddy; Planas-Silva, Maricarmen D; Mahmud, Iqbal; Rajapakshe, Kimal; Coarfa, Cristian; Knapp, Stefan; Lorenzi, Philip L; Kemp, Bruce E; Turk, Benjamin E; Scott, John W; Means, Anthony R; York, Brian Molecular metabolism 35562082 2022 08
Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen. Wotton, Janine M; Peterson, Emma; Flenniken, Ann M; Bains, Rasneer S; Veeraragavan, Surabi; Bower, Lynette R; Bubier, Jason A; Parisien, Marc; Bezginov, Alexandr; Haselimashhadi, Hamed; Mason, Jeremy; Moore, Michayla A; Stewart, Michelle E; Clary, Dave A; Delbarre, Daniel J; Anderson, Laura C; D'Souza, Abigail; Goodwin, Leslie O; Harrison, Mark E; Huang, Ziyue; Mckay, Matthew; Qu, Dawei; Santos, Luis; Srinivasan, Subhiksha; Urban, Rachel; Vukobradovic, Igor; Ward, Christopher S; Willett, Amelia M; Braun, Robert E; Brown, Steve D M; Dickinson, Mary E; Heaney, Jason D; Kumar, Vivek; Lloyd, K C Kent; Mallon, Ann-Marie; McKerlie, Colin; Murray, Stephen A; Nutter, Lauryl M J; Parkinson, Helen; Seavitt, John R; Wells, Sara; Samaco, Rodney C; Chesler, Elissa J; Smedley, Damian; Diatchenko, Luda; Baumbauer, Kyle M; Young, Erin E; Bonin, Robert P; Mandillo, Silvia; White, Jacqueline K; International Mouse Phenotyping Consortium Pain 35552317 2022 Jun 01
Mouse mutagenesis and phenotyping to generate models of development and disease. Gridley, Thomas; Murray, Stephen A Current topics in developmental biology 35461561 2022
Phenotype-driven approaches to enhance variant prioritization and diagnosis of rare disease. Jacobsen, Julius O B; Kelly, Catherine; Cipriani, Valentina; Research Consortium, Genomics England; Mungall, Christopher J; Reese, Justin; Danis, Daniel; Robinson, Peter N; Smedley, Damian Human mutation 35391505 2022 Apr 07
Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism. Meng, Huan; Gonzales, Naomi M; Jung, Sung Yun; Lu, Yue; Putluri, Nagireddy; Zhu, Bokai; Dacso, Clifford C; Lonard, David M; O'Malley, Bert W Cell reports 35263593 2022 03 08
ADAD2 regulates heterochromatin in meiotic and post-meiotic male germ cells via translation of MDC1. Chukrallah, Lauren G; Badrinath, Aditi; Vittor, Gabrielle G; Snyder, Elizabeth M Journal of cell science 35191498 2022 02 15
LMOD2-related dilated cardiomyopathy presenting in late infancy. Lay, Erica; Azamian, Mahshid S; Denfield, Susan W; Dreyer, William; Spinner, Joseph A; Kearney, Debra; Zhang, Lilei; Worley, Kim C; Bi, Weimin; Lalani, Seema R American journal of medical genetics. Part A 35188328 2022 Feb 21
Making sense of the linear genome, gene function and TADs. Long, Helen S; Greenaway, Simon; Powell, George; Mallon, Ann-Marie; Lindgren, Cecilia M; Simon, Michelle M Epigenetics & chromatin 35090532 2022 01 29
Myocardial Rev-erb-Mediated Diurnal Metabolic Rhythm and Obesity Paradox. Song, Shiyang; Tien, Chih-Liang; Cui, Hao; Basil, Paul; Zhu, Ningxia; Gong, Yingyun; Li, Wenbo; Li, Hui; Fan, Qiying; Min Choi, Jong; Luo, Weijia; Xue, Yanfeng; Cao, Rui; Zhou, Wenjun; Ortiz, Andrea R; Stork, Brittany; Mundra, Vatsala; Putluri, Nagireddy; York, Brian; Chu, Maoping; Chang, Jiang; Yun Jung, Sung; Xie, Liang; Song, Jiangping; Zhang, Lilei; Sun, Zheng Circulation 35034472 2022 02 08
Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice. Wu, Yifan; Li, Evan; Knight, Morgan; Adeniyi-Ipadeola, Grace; Song, Li-Zhen; Burns, Alan R; Gazzinelli-Guimaraes, Ana Clara; Fujiwara, Ricardo; Bottazzi, Maria Elena; Weatherhead, Jill E PLoS neglected tropical diseases 34914687 2021 12
Dimensional reduction of phenotypes from 53 000 mouse models reveals a diverse landscape of gene function. Konopka, Tomasz; Vestito, Letizia; Smedley, Damian Bioinformatics advances 34870209 2021
100,000 Genomes Pilot on Rare-Disease Diagnosis in Health Care - Preliminary Report. 100,000 Genomes Project Pilot Investigators; Smedley, Damian; Smith, Katherine R; Martin, Antonio; Thomas, Ellen A; McDonagh, Ellen M; Cipriani, Valentina; Ellingford, Jamie M; Arno, Gavin; Tucci, Arianna; Vandrovcova, Jana; Chan, Georgia; Williams, Hywel J; Ratnaike, Thiloka; Wei, Wei; Stirrups, Kathleen; Ibanez, Kristina; Moutsianas, Loukas; Wielscher, Matthias; Need, Anna; Barnes, Michael R; Vestito, Letizia; Buchanan, James; Wordsworth, Sarah; Ashford, Sofie; Rehmström, Karola; Li, Emily; Fuller, Gavin; Twiss, Philip; Spasic-Boskovic, Olivera; Halsall, Sally; Floto, R Andres; Poole, Kenneth; Wagner, Annette; Mehta, Sarju G; Gurnell, Mark; Burrows, Nigel; James, Roger; Penkett, Christopher; Dewhurst, Eleanor; Gräf, Stefan; Mapeta, Rutendo; Kasanicki, Mary; Haworth, Andrea; Savage, Helen; Babcock, Melanie; Reese, Martin G; Bale, Mark; Baple, Emma; Boustred, Christopher; Brittain, Helen; de Burca, Anna; Bleda, Marta; Devereau, Andrew; Halai, Dina; Haraldsdottir, Eik; Hyder, Zerin; Kasperaviciute, Dalia; Patch, Christine; Polychronopoulos, Dimitris; Matchan, Angela; Sultana, Razvan; Ryten, Mina; Tavares, Ana L T; Tregidgo, Carolyn; Turnbull, Clare; Welland, Matthew; Wood, Suzanne; Snow, Catherine; Williams, Eleanor; Leigh, Sarah; Foulger, Rebecca E; Daugherty, Louise C; Niblock, Olivia; Leong, Ivone U S; Wright, Caroline F; Davies, Jim; Crichton, Charles; Welch, James; Woods, Kerrie; Abulhoul, Lara; Aurora, Paul; Bockenhauer, Detlef; Broomfield, Alexander; Cleary, Maureen A; Lam, Tanya; Dattani, Mehul; Footitt, Emma; Ganesan, Vijeya; Grunewald, Stephanie; Compeyrot-Lacassagne, Sandrine; Muntoni, Francesco; Pilkington, Clarissa; Quinlivan, Rosaline; Thapar, Nikhil; Wallis, Colin; Wedderburn, Lucy R; Worth, Austen; Bueser, Teofila; Compton, Cecilia; Deshpande, Charu; Fassihi, Hiva; Haque, Eshika; Izatt, Louise; Josifova, Dragana; Mohammed, Shehla; Robert, Leema; Rose, Sarah; Ruddy, Deborah; Sarkany, Robert; Say, Genevieve; Shaw, Adam C; Wolejko, Agata; Habib, Bishoy; Burns, Gavin; Hunter, Sarah; Grocock, Russell J; Humphray, Sean J; Robinson, Peter N; Haendel, Melissa; Simpson, Michael A; Banka, Siddharth; Clayton-Smith, Jill; Douzgou, Sofia; Hall, Georgina; Thomas, Huw B; O'Keefe, Raymond T; Michaelides, Michel; Moore, Anthony T; Malka, Sam; Pontikos, Nikolas; Browning, Andrew C; Straub, Volker; Gorman, Gráinne S; Horvath, Rita; Quinton, Richard; Schaefer, Andrew M; Yu-Wai-Man, Patrick; Turnbull, Doug M; McFarland, Robert; Taylor, Robert W; O'Connor, Emer; Yip, Janice; Newland, Katrina; Morris, Huw R; Polke, James; Wood, Nicholas W; Campbell, Carolyn; Camps, Carme; Gibson, Kate; Koelling, Nils; Lester, Tracy; Németh, Andrea H; Palles, Claire; Patel, Smita; Roy, Noemi B A; Sen, Arjune; Taylor, John; Cacheiro, Pilar; Jacobsen, Julius O; Seaby, Eleanor G; Davison, Val; Chitty, Lyn; Douglas, Angela; Naresh, Kikkeri; McMullan, Dom; Ellard, Sian; Temple, I Karen; Mumford, Andrew D; Wilson, Gill; Beales, Phil; Bitner-Glindzicz, Maria; Black, Graeme; Bradley, John R; Brennan, Paul; Burn, John; Chinnery, Patrick F; Elliott, Perry; Flinter, Frances; Houlden, Henry; Irving, Melita; Newman, William; Rahman, Shamima; Sayer, John A; Taylor, Jenny C; Webster, Andrew R; Wilkie, Andrew O M; Ouwehand, Willem H; Raymond, F Lucy; Chisholm, John; Hill, Sue; Bentley, David; Scott, Richard H; Fowler, Tom; Rendon, Augusto; Caulfield, Mark The New England journal of medicine 34758253 2021 11 11
Progress towards completing the mutant mouse null resource. Peterson, Kevin A; Murray, Stephen A Mammalian genome : official journal of the International Mammalian Genome Society 34698892 2021 Oct 26
A metabolome atlas of the aging mouse brain. Ding, Jun; Ji, Jian; Rabow, Zachary; Shen, Tong; Folz, Jacob; Brydges, Christopher R; Fan, Sili; Lu, Xinchen; Mehta, Sajjan; Showalter, Megan R; Zhang, Ying; Araiza, Renee; Bower, Lynette R; Lloyd, K C Kent; Fiehn, Oliver Nature communications 34654818 2021 10 15
PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes. Angelini, Aude; Saha, Pradip K; Jain, Antrix; Jung, Sung Yun; Mynatt, Randall L; Pi, Xinchun; Xie, Liang Cell reports 34610308 2021 10 05
Biology before the SOS Response-DNA Damage Mechanisms at Chromosome Fragile Sites. Fitzgerald, Devon M; Rosenberg, Susan M Cells 34571923 2021 09 01
Importing genetically altered animals: ensuring quality. Birling, M-C; Fray, M D; Kasparek, P; Kopkanova, J; Massimi, M; Matteoni, R; Montoliu, L; Nutter, L M J; Raspa, M; Rozman, J; Ryder, E J; Scavizzi, F; Voikar, V; Wells, S; Pavlovic, G; Teboul, L Mammalian genome : official journal of the International Mammalian Genome Society 34536110 2022 Mar
Pleiotropy data resource as a primer for investigating co-morbidities/multi-morbidities and their role in disease. Muñoz-Fuentes, Violeta; Haselimashhadi, Hamed; Santos, Luis; Westerberg, Henrik; Parkinson, Helen; Mason, Jeremy Mammalian genome : official journal of the International Mammalian Genome Society 34524473 2021 Sep 15
Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy. Hoffman, Kristyn A; Villar, Maria Jose; Poveda, Cristina; Bottazzi, Maria Elena; Hotez, Peter J; Tweardy, David J; Jones, Kathryn M Frontiers in cellular and infection microbiology 34504808 2021
Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Mao, Hua; Li, Luge; Fan, Qiying; Angelini, Aude; Saha, Pradip K; Coarfa, Cristian; Rajapakshe, Kimal; Perera, Dimuthu; Cheng, Jizhong; Wu, Huaizhu; Ballantyne, Christie M; Sun, Zheng; Xie, Liang; Pi, Xinchun Nature communications 34489478 2021 09 06
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes. Lana-Elola, Eva; Cater, Heather; Watson-Scales, Sheona; Greenaway, Simon; Müller-Winkler, Jennifer; Gibbins, Dorota; Nemes, Mihaela; Slender, Amy; Hough, Tertius; Keskivali-Bond, Piia; Scudamore, Cheryl L; Herbert, Eleanor; Banks, Gareth T; Mobbs, Helene; Canonica, Tara; Tosh, Justin; Noy, Suzanna; Llorian, Miriam; Nolan, Patrick M; Griffin, Julian L; Good, Mark; Simon, Michelle; Mallon, Ann-Marie; Wells, Sara; Fisher, Elizabeth M C; Tybulewicz, Victor L J Disease models & mechanisms 34477842 2021 Oct 01
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Vertical transmission of a large calvarial ossification defect due to heterozygous variants of ALX4 and TWIST1. Walters, Michelle E; Lacassie, Yves; Azamian, Mahshid; Franciskovich, Rachel; Zapata, Gladys; Hernandez, Patricia P; Liu, Pengfei; Campbell, Ian M; Bostwick, Bret L; Lalani, Seema R American journal of medical genetics. Part A 33369125 2021 Mar
XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis. Meng, Huan; Gonzales, Naomi M; Lonard, David M; Putluri, Nagireddy; Zhu, Bokai; Dacso, Clifford C; York, Brian; O'Malley, Bert W Nature communications. 33277471 2020 12 04;
Cage-lid hanging behavior as a translationally relevant measure of pain in mice. Zhang, Hantao; Lecker, Irene; Collymore, Chereen; Dokova, Anastassia; Pham, Maian Christine; Rosen, Sarah F; Crawhall-Duk, Hayley; Zain, Maham; Valencia, Megan; Filippini, Helena Fetter; Li, Jerry; D'Souza, Abigail J; Cho, Chulmin; Michailidis, Vassilia; Whissell, Paul D; Patel, Ingita; Steenland, Hendrik W; Virginia Lee, Wai-Jane; Moayedi, Massieh; Sterley, Toni-Lee; Bains, Jaideep S; Stratton, Jo Anne; Matyas, John R; Biernaskie, Jeff; Dubins, David; Vukobradovic, Igor; Bezginov, Alexandr; Flenniken, Ann M; Martin, Loren J; Mogil, Jeffrey S; Bonin, Robert P Pain 33230005 2021 05 01
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Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia. Ward, Christopher S; Huang, Teng-Wei; Herrera, Jose A; Samaco, Rodney C; McGraw, Christopher M; Parra, Diana E; Arvide, E Melissa; Ito-Ishida, Aya; Meng, Xiangling; Ure, Kerstin; Zoghbi, Huda Y; Neul, Jeffrey L Frontiers in neurology. 33193060 2020;
Aurora B and C kinases regulate chromosome desynapsis and segregation during mouse and human spermatogenesis. Wellard, Stephen R; Schindler, Karen; Jordan, Philip W Journal of cell science 33172986 2020 12 04
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Antioxidant Carbon Nanoparticles Inhibit Fibroblast-Like Synoviocyte Invasiveness and Reduce Disease Severity in a Rat Model of Rheumatoid Arthritis. Tanner, Mark R; Huq, Redwan; Sikkema, William K A; Nilewski, Lizanne G; Yosef, Nejla; Schmitt, Cody; Flores-Suarez, Carlos P; Raugh, Arielle; Laragione, Teresina; Gulko, Pércio S; Tour, James M; Beeton, Christine Antioxidants (Basel, Switzerland) 33081234 2020 Oct 16
Anticipating and Identifying Collateral Damage in Genome Editing. Burgio, Gaëtan; Teboul, Lydia Trends in genetics : TIG. 33039248 2020 Dec;
Machine learning-based automated phenotyping of inflammatory nocifensive behavior in mice. Wotton, Janine M; Peterson, Emma; Anderson, Laura; Murray, Stephen A; Braun, Robert E; Chesler, Elissa J; White, Jacqueline K; Kumar, Vivek Molecular pain. 32955381 2020 Jan-Dec;
Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS Data. Sabik, Olivia L; Calabrese, Gina M; Taleghani, Eric; Ackert-Bicknell, Cheryl L; Farber, Charles R Cell reports 32937138 2020 09 15
Interactive and independent effects of early lipopolysaccharide and hyperoxia exposure on developing murine lungs. Shrestha, Amrit Kumar; Menon, Renuka T; El-Saie, Ahmed; Barrios, Roberto; Reynolds, Corey; Shivanna, Binoy American journal of physiology. Lung cellular and molecular physiology 32901520 2020 12 01
Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin. Ong, Seow Theng; Bajaj, Saumya; Tanner, Mark R; Chang, Shih Chieh; Krishnarjuna, Bankala; Ng, Xuan Rui; Morales, Rodrigo A V; Chen, Ming Wei; Luo, Dahai; Patel, Dharmeshkumar; Yasmin, Sabina; Ng, Jeremy Jun Heng; Zhuang, Zhong; Nguyen, Hai M; El Sahili, Abbas; Lescar, Julien; Patil, Rahul; Charman, Susan A; Robins, Edward G; Goggi, Julian L; Tan, Peng Wen; Sadasivam, Pragalath; Ramasamy, Boominathan; Hartimath, Siddana V; Dhawan, Vikas; Bednenko, Janna; Colussi, Paul; Wulff, Heike; Pennington, Michael W; Kuyucak, Serdar; Norton, Raymond S; Beeton, Christine; Chandy, K George ACS pharmacology & translational science. 32832873 2020 Aug 14;
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ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility. Snyder, Elizabeth; Chukrallah, Lauren; Seltzer, Kelly; Goodwin, Leslie; Braun, Robert E Scientific reports. 32665638 2020 Jul 14;
Universal Southern blot protocol with cold or radioactive probes for the validation of alleles obtained by homologous recombination. Codner, Gemma F; Erbs, Valerie; Loeffler, Jorik; Chessum, Lauren; Caulder, Adam; Jullien, Nicolas; Wells, Sara; Birling, Marie-Christine; Teboul, Lydia Methods (San Diego, Calif.) 32599056 2021 07
Somatic Gain of KRAS Function in the Endothelium is Sufficient to Cause Vascular Malformations that Require MEK but not PI3K Signaling. Fish, Jason E; Flores-Suarez, Carlos Perfecto; Boudreau, Emilie; Herman, Alexander M; Gutierrez, Manuel Cantu; Gustafson, Dakota; DiStefano, Peter V; Cui, Meng; Chen, Zhiqi; Berman De Ruiz, Karen; Schexnayder, Taylor S; Ward, Christopher S; Radovanovic, Ivan; Wythe, Joshua D Circulation research. 32552404 2020 Jun 17;
The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities. Herbert, Eleanor; Stewart, Michelle; Hutchison, Marie; Flenniken, Ann M; Qu, Dawei; Nutter, Lauryl M J; McKerlie, Colin; Hobson, Liane; Kick, Brenda; Lyons, Bonnie; Wiegand, Jean-Paul; Doty, Rosalinda; Aguilar-Pimentel, Juan Antonio; Hrabe de Angelis, Martin; Dickinson, Mary; Seavitt, John; White, Jacqueline K; Scudamore, Cheryl L; Wells, Sara PloS one. 32542000 2020;
A global Slc7a7 knockout mouse model demonstrates characteristic phenotypes of human lysinuric protein intolerance. Stroup, Bridget M; Marom, Ronit; Li, Xiaohui; Hsu, Chih-Wei; Chang, Cheng-Yen; Truong, Luan D; Dawson, Brian; Grafe, Ingo; Chen, Yuqing; Jiang, Ming-Ming; Lanza, Denise; Green, Jennie Rose; Sun, Qin; Barrish, J P; Ani, Safa; Christiansen, Audrey E; Seavitt, John R; Dickinson, Mary E; Kheradmand, Farrah; Heaney, Jason D; Lee, Brendan; Burrage, Lindsay C Human molecular genetics 32504080 2020 Aug 03
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DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. Li, Ming-Wen; Lloyd, K C Kent Scientific reports. 32123279 2020 Mar 02;
Chromatin interaction analyses elucidate the roles of PRC2-bound silencers in mouse development. Ngan, Chew Yee; Wong, Chee Hong; Tjong, Harianto; Wang, Wenbo; Goldfeder, Rachel L; Choi, Cindy; He, Hao; Gong, Liang; Lin, Junyan; Urban, Barbara; Chow, Julianna; Li, Meihong; Lim, Joanne; Philip, Vivek; Murray, Stephen A; Wang, Haoyi; Wei, Chia-Lin Nature genetics. 32094912 2020 03;
Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice. Menon, Renuka T; Shrestha, Amrit Kumar; Reynolds, Corey L; Barrios, Roberto; Caron, Kathleen M; Shivanna, Binoy The American journal of pathology. 32093901 2020 03;
PATHBIO: an international training program for precision mouse phenotyping. Ruberte, Jesus; Schofield, Paul N; Brakebusch, Cord; Vogel, Peter; Herault, Yann; Gracia, Guillem; McKerlie, Colin; Hrab? de Angelis, Martin; Hagn, Michael; Sundberg, John P Mammalian genome : official journal of the International Mammalian Genome Society. 32088735 2020 02;
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes. Kollmus, Heike; Fuchs, Helmut; Lengger, Christoph; Haselimashhadi, Hamed; Bogue, Molly A; Östereicher, Manuela A; Horsch, Marion; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Beckers, Johannes; Calzada-Wack, Julia; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M; Klein-Rodewald, Tanja; Maier, Holger; Mayer-Kuckuk, Philipp; Miller, Gregor; Moreth, Kristin; Neff, Frauke; Rathkolb, Birgit; Rácz, Ildikó; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk; Graw, Jochen; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Önder; Mason, Jeremy; Torres, Arturo; Mouse Phenome Database Team; Balling, Rudi; Mehaan, Terry; Gailus-Durner, Valerie; Schughart, Klaus; Hrab? de Angelis, Martin Mammalian genome : official journal of the International Mammalian Genome Society. 32060626 2020 02;
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PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis. Yu, Kwanha; Lin, Chia-Ching John; Hatcher, Asante; Lozzi, Brittney; Kong, Kathleen; Huang-Hobbs, Emmet; Cheng, Yi-Ting; Beechar, Vivek B; Zhu, Wenyi; Zhang, Yiqun; Chen, Fengju; Mills, Gordon B; Mohila, Carrie A; Creighton, Chad J; Noebels, Jeffrey L; Scott, Kenneth L; Deneen, Benjamin Nature. 31996845 2020 02;
Incremental data integration for tracking genotype-disease associations. Konopka, Tomasz; Smedley, Damian PLoS computational biology. 31986132 2020 01;
Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function. Findlay, Amy S; McKie, Lisa; Keighren, Margaret; Clementson-Mobbs, Sharon; Sanchez-Pulido, Luis; Wells, Sara; Cross, Sally H; Jackson, Ian J Scientific reports. 31949211 2020 Jan 16;
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Metabolic dysregulation in the Atp7b-/- Wilson's disease mouse model. Wooton-Kee, Clavia Ruth; Robertson, Matthew; Zhou, Ying; Dong, Bingning; Sun, Zhen; Kim, Kang Ho; Liu, Hailan; Xu, Yong; Putluri, Nagireddy; Saha, Pradip; Coarfa, Cristian; Moore, David D; Nuotio-Antar, Alli M Proceedings of the National Academy of Sciences of the United States of America. 31924743 2020 Jan 28;
Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation. Stevens, Alexandra M; Xiang, Michael; Heppler, Lisa N; To?i?, Isidora; Jiang, Kevin; Munoz, Jaime O; Gaikwad, Amos S; Horton, Terzah M; Long, Xin; Narayanan, Padmini; Seashore, Elizabeth L; Terrell, Maci C; Rashid, Raushan; Krueger, Michael J; Mangubat-Medina, Alicia E; Ball, Zachary T; Sumazin, Pavel; Walker, Sarah R; Hamada, Yoshimasa; Oyadomari, Seiichi; Redell, Michele S; Frank, David A Blood advances. 31856268 2019 12 23;
High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation. Abeler-Dörner, Lucie; Laing, Adam G; Lorenc, Anna; Ushakov, Dmitry S; Clare, Simon; Speak, Anneliese O; Duque-Correa, Maria A; White, Jacqueline K; Ramirez-Solis, Ramiro; Saran, Namita; Bull, Katherine R; Morón, Belén; Iwasaki, Jua; Barton, Philippa R; Caetano, Susana; Hng, Keng I; Cambridge, Emma; Forman, Simon; Crockford, Tanya L; Griffiths, Mark; Kane, Leanne; Harcourt, Katherine; Brandt, Cordelia; Notley, George; Babalola, Kolawole O; Warren, Jonathan; Mason, Jeremy C; Meeniga, Amrutha; Karp, Natasha A; Melvin, David; Cawthorne, Eleanor; Weinrick, Brian; Rahim, Albina; Drissler, Sibyl; Meskas, Justin; Yue, Alice; Lux, Markus; Song-Zhao, George X; Chan, Anna; Ballesteros Reviriego, Carmen; Abeler, Johannes; Wilson, Heather; Przemska-Kosicka, Agnieszka; Edmans, Matthew; Strevens, Natasha; Pasztorek, Markus; Meehan, Terrence F; Powrie, Fiona; Brinkman, Ryan; Dougan, Gordon; Jacobs Jr, William; Lloyd, Clare M; Cornall, Richard J; Maloy, Kevin J; Grencis, Richard K; Griffiths, Gillian M; Adams, David J; Hayday, Adrian C Nature immunology. 31844327 2020 01;
NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells. Gupta, Shubhranshu S; Sharp, Robert; Hofferek, Colby; Kuai, Le; Dorn 2nd, Gerald W; Wang, Jin; Chen, Min Cell reports. 31722203 2019 11 12;
Improved Biomarker and Imaging Analysis for Characterizing Progressive Cardiac Fibrosis in a Mouse Model of Chronic Chagasic Cardiomyopathy. Hoffman, Kristyn A; Reynolds, Corey; Bottazzi, Maria Elena; Hotez, Peter; Jones, Kathryn Journal of the American Heart Association. 31718442 2019 11 19;
Effector gene expression underlying neuron subtype-specific traits in the Motor Ganglion of Ciona. Gibboney, Susanne; Orvis, Jameson; Kim, Kwantae; Johnson, Christopher J; Martinez-Feduchi, Paula; Lowe, Elijah K; Sharma, Sarthak; Stolfi, Alberto Developmental biology. 31639337 2020 Feb 01;
Long-range Pitx2c enhancer-promoter interactions prevent predisposition to atrial fibrillation. Zhang, Min; Hill, Matthew C; Kadow, Zachary A; Suh, Ji Ho; Tucker, Nathan R; Hall, Amelia W; Tran, Tien T; Swinton, Paul S; Leach, John P; Margulies, Kenneth B; Ellinor, Patrick T; Li, Na; Martin, James F Proceedings of the National Academy of Sciences of the United States of America. 31636200 2019 11 05;
Cytoglobin deficiency potentiates Crb1-mediated retinal degeneration in rd8 mice. Kwon, Young Sam; Tham, Addy; Lopez, Antonio Jacobo; Edwards, Sydney; Woods, Sean; Chen, Jiajia; Wong-Fortunato, Jenna; Quiroz Alonso, Alejandra; Javier, Seanne; Au, Ingrid; Clarke, Maria; Humpal, Devin; Lloyd, K C Kent; Thomasy, Sara; Murphy, Christopher; Glaser, Thomas M; Moshiri, Ala Developmental biology. 31634437 2020 Feb 15;
Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae. Jiang, Danye; Burger, Courtney A; Casasent, Anna K; Albrecht, Nicholas E; Li, Fenge; Samuel, Melanie A The Journal of comparative neurology. 31609468 2020 Apr 01;
Soft Windowing Application to Improve Analysis of High-throughput Phenotyping Data. Haselimashhadi, Hamed; Mason, Jeremy C; Munoz-Fuentes, Violeta; López-Gómez, Federico; Babalola, Kolawole; Acar, Elif F; Kumar, Vivek; White, Jacqui; Flenniken, Ann M; King, Ruairidh; Straiton, Ewan; Seavitt, John Richard; Gaspero, Angelina; Garza, Arturo; Christianson, Audrey E; Hsu, Chih-Wei; Reynolds, Corey L; Lanza, Denise G; Lorenzo, Isabel; Green, Jennie R; Gallegos, Juan J; Bohat, Ritu; Samaco, Rodney C; Veeraragavan, Surabi; Kim, Jong Kyoung; Miller, Gregor; Fuchs, Helmult; Garrett, Lillian; Becker, Lore; Kang, Yeon Kyung; Clary, David; Cho, Soo Young; Tamura, Masaru; Tanaka, Nobuhiko; Soo, Kyung Dong; Bezginov, Alexandr; About, Ghina Bou; Champy, Marie-France; Vasseur, Laurent; Leblanc, Sophie; Meziane, Hamid; Selloum, Mohammed; Reilly, Patrick T; Spielmann, Nadine; Maier, Holger; Gailus-Durner, Valerie; Sorg, Tania; Hiroshi, Masuya; Yuichi, Obata; Heaney, Jason D; Dickinson, Mary E; Wolfgang, Wurst; Tocchini-Valentini, Glauco P; Lloyd, Kevin C Kent; McKerlie, Colin; Seong, Je Kyung; Yann, Herault; de Angelis, Martin Hrabé; Brown, Steve D M; Smedley, Damian; Flicek, Paul; Mallon, Ann-Marie; Parkinson, Helen; Meehan, Terrence F Bioinformatics (Oxford, England). 31591642 2019 Oct 08;
Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis. Xiao, Yang; Hill, Matthew C; Li, Lele; Deshmukh, Vaibhav; Martin, Thomas J; Wang, Jun; Martin, James F Genes & development. 31558567 2019 11 01;
Genomic Mutation Identification in Mice Using Illumina Sequencing and Linux-Based Computational Methods. Williams, John A; Powell, George; Mallon, Ann-Marie; Simon, Michelle M Current protocols in mouse biology 31532925 2019 Sep
Endurance exercise leads to beneficial molecular and physiological effects in a mouse model of myotonic dystrophy type 1. Sharp, Lydia; Cox, Diana C; Cooper, Thomas A Muscle & nerve. 31509256 2019 12;
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation. Gurumurthy, Channabasavaiah B; O'Brien, Aidan R; Quadros, Rolen M; Adams Jr, John; Alcaide, Pilar; Ayabe, Shinya; Ballard, Johnathan; Batra, Surinder K; Beauchamp, Marie-Claude; Becker, Kathleen A; Bernas, Guillaume; Brough, David; Carrillo-Salinas, Francisco; Chan, Wesley; Chen, Hanying; Dawson, Ruby; DeMambro, Victoria; D'Hont, Jinke; Dibb, Katharine M; Eudy, James D; Gan, Lin; Gao, Jing; Gonzales, Amy; Guntur, Anyonya R; Guo, Huiping; Harms, Donald W; Harrington, Anne; Hentges, Kathryn E; Humphreys, Neil; Imai, Shiho; Ishii, Hideshi; Iwama, Mizuho; Jonasch, Eric; Karolak, Michelle; Keavney, Bernard; Khin, Nay-Chi; Konno, Masamitsu; Kotani, Yuko; Kunihiro, Yayoi; Lakshmanan, Imayavaramban; Larochelle, Catherine; Lawrence, Catherine B; Li, Lin; Lindner, Volkhard; Liu, Xian-De; Lopez-Castejon, Gloria; Loudon, Andrew; Lowe, Jenna; Jerome-Majewska, Loydie A; Matsusaka, Taiji; Miura, Hiromi; Miyasaka, Yoshiki; Morpurgo, Benjamin; Motyl, Katherine; Nabeshima, Yo-Ichi; Nakade, Koji; Nakashiba, Toshiaki; Nakashima, Kenichi; Obata, Yuichi; Ogiwara, Sanae; Ouellet, Mariette; Oxburgh, Leif; Piltz, Sandra; Pinz, Ilka; Ponnusamy, Moorthy P; Ray, David; Redder, Ronald J; Rosen, Clifford J; Ross, Nikki; Ruhe, Mark T; Ryzhova, Larisa; Salvador, Ane M; Alam, Sabrina Shameen; Sedlacek, Radislav; Sharma, Karan; Smith, Chad; Staes, Katrien; Starrs, Lora; Sugiyama, Fumihiro; Takahashi, Satoru; Tanaka, Tomohiro; Trafford, Andrew W; Uno, Yoshihiro; Vanhoutte, Leen; Vanrockeghem, Frederique; Willis, Brandon J; Wright, Christian S; Yamauchi, Yuko; Yi, Xin; Yoshimi, Kazuto; Zhang, Xuesong; Zhang, Yu; Ohtsuka, Masato; Das, Satyabrata; Garry, Daniel J; Hochepied, Tino; Thomas, Paul; Parker-Thornburg, Jan; Adamson, Antony D; Yoshiki, Atsushi; Schmouth, Jean-Francois; Golovko, Andrei; Thompson, William R; Lloyd, K C Kent; Wood, Joshua A; Cowan, Mitra; Mashimo, Tomoji; Mizuno, Seiya; Zhu, Hao; Kasparek, Petr; Liaw, Lucy; Miano, Joseph M; Burgio, Gaetan Genome biology. 31446895 2019 08 26;
Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. Moore, Bret A; Flenniken, Ann M; Clary, Dave; Moshiri, Ata S; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammad; McKerlie, Colin; International Mouse Phenotyping Consortium; Thomasy, Sara M; Lloyd, K C Kent; Murphy, Christopher J; Moshiri, Ala Scientific reports. 31371754 2019 Aug 01;
Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1. Cyranka, Malgorzata; Veprik, Anna; McKay, Eleanor J; van Loon, Nienke; Thijsse, Amber; Cotter, Luke; Hare, Nisha; Saibudeen, Affan; Lingam, Swathi; Pires, Elisabete; Larraufie, Pierre; Reimann, Frank; Gribble, Fiona; Stewart, Michelle; Bentley, Elizabeth; Lear, Pamela; McCullagh, James; Cantley, James; Cox, Roger D; de Wet, Heidi Obesity (Silver Spring, Md.). 31338999 2019 Aug;
S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation. Ren, Yi Athena; Monkkonen, Teresa; Lewis, Michael T; Bernard, Daniel J; Christian, Helen C; Jorgez, Carolina J; Moore, Joshua A; Landua, John D; Chin, Haelee M; Chen, Weiqin; Singh, Swarnima; Kim, Ik Sun; Zhang, Xiang Hf; Xia, Yan; Phillips, Kevin J; MacKay, Harry; Waterland, Robert A; Ljungberg, M Cecilia; Saha, Pradip K; Hartig, Sean M; Coll, Tatiana Fiordelisio; Richards, JoAnne S JCI insight. 31265437 2019 Jul 02;
Bmi1 Suppresses Adipogenesis in the Hematopoietic Stem Cell Niche. Hu, Tianyuan; Kitano, Ayumi; Luu, Victor; Dawson, Brian; Hoegenauer, Kevin A; Lee, Brendan H; Nakada, Daisuke Stem cell reports. 31257132 2019 Sep 10;
Luciferase Reporter Mice for In Vivo Monitoring and Ex Vivo Assessment of Hypothalamic Signaling of Socs3 Expression. Cordonier, Elizabeth L; Liu, Tiemin; Saito, Kenji; Chen, Siyu S; Xu, Yong; Fukuda, Makoto Journal of the Endocrine Society. 31214662 2019 Jul 01;
A cellular atlas of Pitx2-dependent cardiac development. Hill, Matthew C; Kadow, Zachary A; Li, Lele; Tran, Tien T; Wythe, Joshua D; Martin, James F Development (Cambridge, England). 31201182 2019 Jun 14;
High Resolution Imaging of Mouse Embryos and Neonates with X-Ray Micro-Computed Tomography. Hsu, Chih-Wei; Kalaga, Sowmya; Akoma, Uchechukwu; Rasmussen, Tara L; Christiansen, Audrey E; Dickinson, Mary E Current protocols in mouse biology. 31195428 2019 Jun;
Progressive myoclonic epilepsy-associated gene Kctd7 regulates retinal neurovascular patterning and function. Alevy, Jonathan; Burger, Courtney A; Albrecht, Nicholas E; Jiang, Danye; Samuel, Melanie A Neurochemistry international. 31175897 2019 Oct;
Non-monotonic dose-response effects of arsenic on glucose metabolism. Gong, Yingyun; Liu, Jidong; Xue, Yanfeng; Zhuang, Zhong; Qian, Sichong; Zhou, Wenjun; Li, Xin; Qian, Justin; Ding, Guolian; Sun, Zheng Toxicology and applied pharmacology. 31170414 2019 Aug 15;
New models for human disease from the International Mouse Phenotyping Consortium. Cacheiro, Pilar; Haendel, Melissa A; Smedley, Damian; International Mouse Phenotyping Consortium and the Monarch Initiative Mammalian genome : official journal of the International Mammalian Genome Society. 31127358 2019 Jun;
A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium. Barupal, Dinesh K; Zhang, Ying; Shen, Tong; Fan, Sili; Roberts, Bryan S; Fitzgerald, Patrick; Wancewicz, Benjamin; Valdiviez, Luis; Wohlgemuth, Gert; Byram, Gregory; Choy, Ying Yng; Haffner, Bennett; Showalter, Megan R; Vaniya, Arpana; Bloszies, Clayton S; Folz, Jacob S; Kind, Tobias; Flenniken, Ann M; McKerlie, Colin; Nutter, Lauryl M J; Lloyd, Kent C; Fiehn, Oliver Metabolites. 31121816 2019 May 22;
-Omics biomarker identification pipeline for translational medicine. Bravo-Merodio, Laura; Williams, John A; Gkoutos, Georgios V; Acharjee, Animesh Journal of translational medicine. 31088492 2019 05 14;
The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming. Rueda, Elda M; Hall, Benjamin M; Hill, Matthew C; Swinton, Paul G; Tong, Xuefei; Martin, James F; Poché, Ross A Cell reports. 31067451 2019 May 07;
TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells. Arhatte, Malika; Gunaratne, Gihan S; El Boustany, Charbel; Kuo, Ivana Y; Moro, Céline; Duprat, Fabrice; Plaisant, Magali; Duval, Hélène; Li, Dahui; Picard, Nicolas; Couvreux, Anais; Duranton, Christophe; Rubera, Isabelle; Pagnotta, Sophie; Lacas-Gervais, Sandra; Ehrlich, Barbara E; Marchant, Jonathan S; Savage, Aaron M; van Eeden, Fredericus J M; Wilkinson, Robert N; Demolombe, Sophie; Honoré, Eric; Patel, Amanda Nature communications. 31048699 2019 05 02;
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. Falcão, Ana Mendanha; Meijer, Mandy; Scaglione, Antonella; Rinwa, Puneet; Agirre, Eneritz; Liang, Jialiang; Larsen, Sara C; Heskol, Abeer; Frawley, Rebecca; Klingener, Michael; Varas-Godoy, Manuel; Raposo, Alexandre A S F; Ernfors, Patrik; Castro, Diogo S; Nielsen, Michael L; Casaccia, Patrizia; Castelo-Branco, Gonçalo Cell reports. 31018126 2019 Apr 23;
Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction. Li, Qiang; Youn, Ji Youn; Siu, Kin Lung; Murugesan, Priya; Zhang, Yixuan; Cai, Hua Redox biology. 30954686 2019 Jun;
Robust mouse tracking in complex environments using neural networks. Geuther, Brian Q; Deats, Sean P; Fox, Kai J; Murray, Steve A; Braun, Robert E; White, Jacqueline K; Chesler, Elissa J; Lutz, Cathleen M; Kumar, Vivek Communications biology. 30937403 2019;
Integrative transcriptomic analysis suggests new autoregulatory splicing events coupled with nonsense-mediated mRNA decay. Pervouchine, Dmitri; Popov, Yaroslav; Berry, Andy; Borsari, Beatrice; Frankish, Adam; Guigó, Roderic Nucleic acids research. 30916337 2019 Jun 04;
Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression. Kumagai, Motona; Guo, Xin; Wang, Ke-Yong; Izumi, Hiroto; Tsukamoto, Manabu; Nakashima, Tamiji; Tasaki, Takashi; Kurose, Nozomu; Uramoto, Hidetaka; Sasaguri, Yasuyuki; Kohno, Kimitoshi; Yamada, Sohsuke International journal of medical sciences. 30911276 2019;
Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts. Moore, Bret A; Leonard, Brian C; Sebbag, Lionel; Edwards, Sydney G; Cooper, Ann; Imai, Denise M; Straiton, Ewan; Santos, Luis; Reilly, Christopher; Griffey, Stephen M; Bower, Lynette; Clary, David; Mason, Jeremy; Roux, Michel J; Meziane, Hamid; Herault, Yann; International Mouse Phenotyping Consortium; McKerlie, Colin; Flenniken, Ann M; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammed; Hsu, Chih-Wei; Kalaga, Sowmya; Udensi, Uchechukwu; Asomugha, Chinwe; Bohat, Ritu; Gallegos, Juan J; Seavitt, John R; Heaney, Jason D; Beaudet, Arthur L; Dickinson, Mary E; Justice, Monica J; Philip, Vivek; Kumar, Vivek; Svenson, Karen L; Braun, Robert E; Wells, Sara; Cater, Heather; Stewart, Michelle; Clementson-Mobbs, Sharon; Joynson, Russell; Gao, Xiang; Suzuki, Tomohiro; Wakana, Shigeharu; Smedley, Damian; Seong, J K; Tocchini-Valentini, Glauco; Moore, Mark; Fletcher, Colin; Karp, Natasha; Ramirez-Solis, Ramiro; White, Jacqueline K; de Angelis, Martin Hrabe; Wurst, Wolfgang; Thomasy, Sara M; Flicek, Paul; Parkinson, Helen; Brown, Steve D M; Meehan, Terrence F; Nishina, Patsy M; Murray, Stephen A; Krebs, Mark P; Mallon, Ann-Marie; Kent Lloyd, K C; Murphy, Christopher J; Moshiri, Ala Communications biology. 30854487 2019;
Cytohesin-3 is required for full insulin receptor signaling and controls body weight via lipid excretion. Jux, Bettina; Gosejacob, Dominic; Tolksdorf, Felix; Mandel, Christa; Rieck, Michael; Namislo, Angrit; Pfeifer, Alexander; Kolanus, Waldemar Scientific reports. 30837656 2019 Mar 05;
Ocular phenotypic consequences of a single copy deletion of the Yap1 gene (Yap1+/-) in mice. Kim, Soohyun; Thomasy, Sara M; Raghunathan, Vijay Krishna; Teixeira, Leandro B C; Moshiri, Ala; FitzGerald, Paul; Murphy, Christopher J Molecular vision. 30820148 2019;
Tead1 is required for perinatal cardiomyocyte proliferation. Liu, Ruya; Jagannathan, Rajaganapathi; Li, Feng; Lee, Jeongkyung; Balasubramanyam, Nikhil; Kim, Byung S; Yang, Ping; Yechoor, Vijay K; Moulik, Mousumi PloS one. 30811446 2019;
YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo. Monroe, Tanner O; Hill, Matthew C; Morikawa, Yuka; Leach, John P; Heallen, Todd; Cao, Shuyi; Krijger, Peter H L; de Laat, Wouter; Wehrens, Xander H T; Rodney, George G; Martin, James F Developmental cell. 30773489 2019 Mar 25;
Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. Burrage, Lindsay C; Reynolds, John J; Baratang, Nissan Vida; Phillips, Jennifer B; Wegner, Jeremy; McFarquhar, Ashley; Higgs, Martin R; Christiansen, Audrey E; Lanza, Denise G; Seavitt, John R; Jain, Mahim; Li, Xiaohui; Parry, David A; Raman, Vandana; Chitayat, David; Chinn, Ivan K; Bertuch, Alison A; Karaviti, Lefkothea; Schlesinger, Alan E; Earl, Dawn; Bamshad, Michael; Savarirayan, Ravi; Doddapaneni, Harsha; Muzny, Donna; Jhangiani, Shalini N; Eng, Christine M; Gibbs, Richard A; Bi, Weimin; Emrick, Lisa; Rosenfeld, Jill A; Postlethwait, John; Westerfield, Monte; Dickinson, Mary E; Beaudet, Arthur L; Ranza, Emmanuelle; Huber, Celine; Cormier-Daire, Valérie; Shen, Wei; Mao, Rong; Heaney, Jason D; Orange, Jordan S; University of Washington Center for Mendelian Genomics; Undiagnosed Diseases Network; Bertola, Débora; Yamamoto, Guilherme L; Baratela, Wagner A R; Butler, Merlin G; Ali, Asim; Adeli, Mehdi; Cohn, Daniel H; Krakow, Deborah; Jackson, Andrew P; Lees, Melissa; Offiah, Amaka C; Carlston, Colleen M; Carey, John C; Stewart, Grant S; Bacino, Carlos A; Campeau, Philippe M; Lee, Brendan American journal of human genetics. 30773277 2019 Mar 07;
Transcriptional analysis of Foxp3+ Tregs and functions of two identified molecules during resolution of ALI. Mock, Jason R; Dial, Catherine F; Tune, Miriya K; Norton, Dustin L; Martin, Jessica R; Gomez, John C; Hagan, Robert S; Dang, Hong; Doerschuk, Claire M JCI insight. 30753170 2019 Mar 21;
Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche. Salazar, Valerie S; Capelo, Luciane P; Cantù, Claudio; Zimmerli, Dario; Gosalia, Nehal; Pregizer, Steven; Cox, Karen; Ohte, Satoshi; Feigenson, Marina; Gamer, Laura; Nyman, Jeffry S; Carey, David J; Economides, Aris; Basler, Konrad; Rosen, Vicki eLife. 30735122 2019 Feb 08;
Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities. Stewart, Michelle; Lau, Petrina; Banks, Gareth; Bains, Rasneer Sonia; Castroflorio, Enrico; Oliver, Peter L; Dixon, Christine L; Kruer, Michael C; Kullmann, Dimitri M; Acevedo-Arozena, Abraham; Wells, Sara E; Corrochano, Silvia; Nolan, Patrick M Disease models & mechanisms. 30692144 2019 Feb 22;
Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Zhou, Wenjun; He, Yanlin; Rehman, Atteeq U; Kong, Yan; Hong, Sungguan; Ding, Guolian; Yalamanchili, Hari Krishna; Wan, Ying-Wooi; Paul, Basil; Wang, Chuhan; Gong, Yingyun; Zhou, Wenxian; Liu, Hao; Dean, John; Scalais, Emmanuel; O'Driscoll, Mary; Morton, Jenny E V; DDD study; Hou, Xinguo; Wu, Qi; Tong, Qingchun; Liu, Zhandong; Liu, Pengfei; Xu, Yong; Sun, Zheng Nature neuroscience. 30664766 2019 02;
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis. Goodwin, Leslie O; Splinter, Erik; Davis, Tiffany L; Urban, Rachel; He, Hao; Braun, Robert E; Chesler, Elissa J; Kumar, Vivek; van Min, Max; Ndukum, Juliet; Philip, Vivek M; Reinholdt, Laura G; Svenson, Karen; White, Jacqueline K; Sasner, Michael; Lutz, Cathleen; Murray, Stephen A Genome research. 30659012 2019 Mar;
Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma. Monsivais, Diana; Peng, Jia; Kang, Yibin; Matzuk, Martin M Proceedings of the National Academy of Sciences of the United States of America. 30655341 2019 Feb 26;
Using CRISPR/Cas9 engineering to generate a mouse with a conditional knockout allele for the promyelocytic leukemia zinc finger transcription factor. Hai, Lan; Szwarc, Maria M; Lanza, Denise G; Heaney, Jason D; Lydon, John P Genesis (New York, N.Y. : 2000). 30628160 2019 Mar;
Generating mouse models for biomedical research: technological advances. Gurumurthy, Channabasavaiah B; Lloyd, Kevin C Kent Disease models & mechanisms. 30626588 2019 01 08;
Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults. Lo Re, Oriana; Mazza, Tommaso; Vinciguerra, Manlio Frontiers in genetics. 30619475 2018;
KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis. Tanner, Mark R; Pennington, Michael W; Chauhan, Satendra S; Laragione, Teresina; Gulko, Pércio S; Beeton, Christine Arthritis research & therapy. 30612588 2019 Jan 07;
Identification of genes required for eye development by high-throughput screening of mouse knockouts. Moore, Bret A; Leonard, Brian C; Sebbag, Lionel; Edwards, Sydney G; Cooper, Ann; Imai, Denise M; Straiton, Ewan; Santos, Luis; Reilly, Christopher; Griffey, Stephen M; Bower, Lynette; Clary, David; Mason, Jeremy; Roux, Michel J; Meziane, Hamid; Herault, Yann; International Mouse Phenotyping Consortium; McKerlie, Colin; Flenniken, Ann M; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammed; Hsu, Chih-Wei; Kalaga, Sowmya; Udensi, Uchechukwu; Asomugha, Chinwe; Bohat, Ritu; Gallegos, Juan J; Seavitt, John R; Heaney, Jason D; Beaudet, Arthur L; Dickinson, Mary E; Justice, Monica J; Philip, Vivek; Kumar, Vivek; Svenson, Karen L; Braun, Robert E; Wells, Sara; Cater, Heather; Stewart, Michelle; Clementson-Mobbs, Sharon; Joynson, Russell; Gao, Xiang; Suzuki, Tomohiro; Wakana, Shigeharu; Smedley, Damian; Seong, J K; Tocchini-Valentini, Glauco; Moore, Mark; Fletcher, Colin; Karp, Natasha; Ramirez-Solis, Ramiro; White, Jacqueline K; de Angelis, Martin Hrabe; Wurst, Wolfgang; Thomasy, Sara M; Flicek, Paul; Parkinson, Helen; Brown, Steve D M; Meehan, Terrence F; Nishina, Patsy M; Murray, Stephen A; Krebs, Mark P; Mallon, Ann-Marie; Lloyd, K C Kent; Murphy, Christopher J; Moshiri, Ala Communications biology. 30588515 2018;
Gi/o protein-coupled receptors in dopamine neurons inhibit the sodium leak channel NALCN. Philippart, Fabian; Khaliq, Zayd M eLife. 30556810 2018 12 17;
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice. Xu, Wenqiong; Zhou, Hongyi; Xuan, Hongzhuan; Saha, Pradip; Wang, Gongxian; Chen, Weiqin Molecular and cellular endocrinology. 30521848 2019 Feb 15;
Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model. Kim, Hyeongseok; Kim, Yeong Gi; Choi, Wonsuk; Moon, Joon Ho; Hwang, Inseon; Kim, Kyuho; Yadav, Vijay K; Karsenty, Gerard; Jeong, Ji-Seon; Kim, Hail Scientific reports. 30518775 2018 Dec 05;
Utility of HbA1c assessment in people with diabetes awaiting liver transplantation. Bhattacharjee, D; Vracar, S; Round, R A; Nightingale, P G; Williams, J A; Gkoutos, G V; Stratton, I M; Parker, R; Luzio, S D; Webber, J; Manley, S E; Roberts, G A; Ghosh, S Diabetic medicine : a journal of the British Diabetic Association. 30474191 2018 Nov 26;
IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections. Shepardson, Kelly M; Larson, Kyle; Johns, Laura L; Stanek, Kayla; Cho, Hanbyul; Wellham, Julia; Henderson, Haley; Rynda-Apple, Agnieszka Frontiers in immunology. 30473701 2018;
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The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex. Panda, Swarupa; Gekara, Nelson O Nature communications. 30405132 2018 11 07;
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Engineering Point Mutant and Epitope-Tagged Alleles in Mice Using Cas9 RNA-Guided Nuclease. Gertsenstein, Marina; Nutter, Lauryl M J Current protocols in mouse biology. 30040228 2018 Mar;
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Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles. Lanza, Denise G; Gaspero, Angelina; Lorenzo, Isabel; Liao, Lan; Zheng, Ping; Wang, Ying; Deng, Yu; Cheng, Chonghui; Zhang, Chuansheng; Seavitt, John R; DeMayo, Francesco J; Xu, Jianming; Dickinson, Mary E; Beaudet, Arthur L; Heaney, Jason D BMC biology. 29925370 2018 Jun 21;
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Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity. Zhang, Ming-Dong; Su, Jie; Adori, Csaba; Cinquina, Valentina; Malenczyk, Katarzyna; Girach, Fatima; Peng, Changgeng; Ernfors, Patrik; Löw, Peter; Borgius, Lotta; Kiehn, Ole; Watanabe, Masahiko; Uhlén, Mathias; Mitsios, Nicholas; Mulder, Jan; Harkany, Tibor; Hökfelt, Tomas The Journal of clinical investigation. 29893745 2018 08 31;
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High-resolution ?CT of a mouse embryo using a compact laser-driven X-ray betatron source. Cole, Jason M; Symes, Daniel R; Lopes, Nelson C; Wood, Jonathan C; Poder, Kristjan; Alatabi, Saleh; Botchway, Stanley W; Foster, Peta S; Gratton, Sarah; Johnson, Sara; Kamperidis, Christos; Kononenko, Olena; De Lazzari, Michael; Palmer, Charlotte A J; Rusby, Dean; Sanderson, Jeremy; Sandholzer, Michael; Sarri, Gianluca; Szoke-Kovacs, Zsombor; Teboul, Lydia; Thompson, James M; Warwick, Jonathan R; Westerberg, Henrik; Hill, Mark A; Norris, Dominic P; Mangles, Stuart P D; Najmudin, Zulfikar Proceedings of the National Academy of Sciences of the United States of America. 29871946 2018 06 19;
A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice. Moore, Bret A; Roux, Michel J; Sebbag, Lionel; Cooper, Ann; Edwards, Sydney G; Leonard, Brian C; Imai, Denise M; Griffey, Stephen; Bower, Lynette; Clary, Dave; Lloyd, K C Kent; Hérault, Yann; Thomasy, Sara M; Murphy, Christopher J; Moshiri, Ala Investigative ophthalmology & visual science. 29847629 2018 May 01;
Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation. Yao, Chunxia; Veleva, Tina; Scott Jr, Larry; Cao, Shuyi; Li, Luge; Chen, Gong; Jeyabal, Prince; Pan, Xiaolu; Alsina, Katherina M; Abu-Taha Dr, Issam; Ghezelbash, Shokoufeh; Reynolds, Corey L; Shen, Ying H; LeMaire, Scott A; Schmitz, Wilhelm; Müller, Frank U; El-Armouche, Ali; Tony Eissa, N; Beeton, Christine; Nattel, Stanley; Wehrens, Xander H T; Dobrev, Dobromir; Li, Na Circulation. 29802206 2018 11 13;
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Efficient mouse genome engineering by CRISPR-EZ technology. Modzelewski, Andrew J; Chen, Sean; Willis, Brandon J; Lloyd, K C Kent; Wood, Joshua A; He, Lin Nature protocols. 29748649 2018 06;
SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program. Ratnadiwakara, Madara; Archer, Stuart K; Dent, Craig I; Ruiz De Los Mozos, Igor; Beilharz, Traude H; Knaupp, Anja S; Nefzger, Christian M; Polo, Jose M; Anko, Minna-Liisa eLife. 29741478 2018 05 09;
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Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome. De Pace, Raffaella; Skirzewski, Miguel; Damme, Markus; Mattera, Rafael; Mercurio, Jeffrey; Foster, Arianne M; Cuitino, Loreto; Jarnik, Michal; Hoffmann, Victoria; Morris, H Douglas; Han, Tae-Un; Mancini, Grazia M S; Buonanno, Andrés; Bonifacino, Juan S PLoS genetics. 29698489 2018 04;
Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development. Xiao, Yang; Hill, Matthew C; Zhang, Min; Martin, Thomas J; Morikawa, Yuka; Wang, Suya; Moise, Alexander R; Wythe, Joshua D; Martin, James F Developmental cell. 29689192 2018 04 23;
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IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer. You, Ran; DeMayo, Francesco J; Liu, Jian; Cho, Sung-Nam; Burt, Bryan M; Creighton, Chad J; Casal, Roberto F; Lazarus, Donald R; Lu, Wen; Tung, Hui-Ying; Yuan, Xiaoyi; Hill-McAlester, Andrea; Kim, Myunghoo; Perusich, Sarah; Cornwell, Loraine; Rosen, Daniel; Song, Li-Zhen; Paust, Silke; Diehl, Gretchen; Corry, David; Kheradmand, Farrah Cancer immunology research. 29653981 2018 06;
Renal proteomic analysis of RGC-32 knockout mice reveals the potential mechanism of RGC-32 in regulating cell cycle. Hu, Yu-Jie; Zhou, Qian; Li, Zhu-Yin; Feng, Dan; Sun, Lei; Shen, Yun-Lin; Huang, Wen-Yan American journal of translational research. 29636874 2018;
High-throughput mouse phenomics for characterizing mammalian gene function. Brown, Steve D M; Holmes, Chris C; Mallon, Ann-Marie; Meehan, Terrence F; Smedley, Damian; Wells, Sara Nature reviews. Genetics. 29626206 2018 Jun;
The role of FREM2 and FRAS1 in the development of congenital diaphragmatic hernia. Jordan, Valerie K; Beck, Tyler F; Hernandez-Garcia, Andres; Kundert, Peter N; Kim, Bum-Jun; Jhangiani, Shalini N; Gambin, Tomasz; Starkovich, Molly; Punetha, Jaya; Paine, Ingrid S; Posey, Jennifer E; Li, Alexander H; Muzny, Donna; Hsu, Chih-Wei; Lashua, Amber J; Sun, Xin; Fernandes, Caraciolo J; Dickinson, Mary E; Lally, Kevin P; Gibbs, Richard A; Boerwinkle, Eric; Lupski, James R; Scott, Daryl A Human molecular genetics. 29618029 2018 06 15;
Response to ''Unexpected mutations after CRISPR-Cas9 editing in vivo''. Nutter, Lauryl M J; Heaney, Jason D; Lloyd, K C Kent; Murray, Stephen A; Seavitt, John R; Skarnes, William C; Teboul, Lydia; Brown, Steve D M; Moore, Mark Nature methods. 29600991 2018 Apr;
Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice. Wang, Ke-Yong; Yamada, Sohsuke; Izumi, Hiroto; Tsukamoto, Manabu; Nakashima, Tamiji; Tasaki, Takashi; Guo, Xin; Uramoto, Hidetaka; Sasaguri, Yasuyuki; Kohno, Kimitoshi PloS one. 29596490 2018;
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Dynamic Imaging of Mouse Embryos and Cardiodynamics in Static Culture. Lopez 3rd, Andrew L; Larina, Irina V Methods in molecular biology (Clifton, N.J.). 29564760 2018;
Loss of the Intellectual Disability and Autism Gene Cc2d1a and Its Homolog Cc2d1b Differentially Affect Spatial Memory, Anxiety, and Hyperactivity. Zamarbide, Marta; Oaks, Adam W; Pond, Heather L; Adelman, Julia S; Manzini, M Chiara Frontiers in genetics. 29552027 2018;
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining. Li, Conglei; Irrazabal, Thergiory; So, Clare C; Berru, Maribel; Du, Likun; Lam, Evelyn; Ling, Alexanda K; Gommerman, Jennifer L; Pan-Hammarström, Qiang; Martin, Alberto Nature communications. 29520062 2018 03 08;
Contribution of metabolic disease to bone fragility in MAGP1-deficient mice. Turecamo, S E; Walji, T A; Broekelmann, T J; Williams, J W; Ivanov, S; Wee, N K; Procknow, J D; McManus, M R; Randolph, G J; Scheller, E L; Mecham, R P; Craft, C S Matrix biology : journal of the International Society for Matrix Biology. 29519758 2018 04;
Loss of cone function without degeneration in a novel Gnat2 knock-out mouse. Ronning, Kaitryn E; Allina, Gabriel Peinado; Miller, Eric B; Zawadzki, Robert J; Pugh Jr, Edward N; Herrmann, Rolf; Burns, Marie E Experimental eye research. 29518352 2018 06;
TRPV6, TRPM6 and TRPM7 Do Not Contribute to Hair-Cell Mechanotransduction. Morgan, Clive P; Zhao, Hongyu; LeMasurier, Meredith; Xiong, Wei; Pan, Bifeng; Kazmierczak, Piotr; Avenarius, Matthew R; Bateschell, Michael; Larisch, Ruby; Ricci, Anthony J; Müller, Ulrich; Barr-Gillespie, Peter G Frontiers in cellular neuroscience. 29515374 2018;
SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function. Matt, Lucas; Kirk, Lyndsey M; Chenaux, George; Speca, David J; Puhger, Kyle R; Pride, Michael C; Qneibi, Mohammad; Haham, Tomer; Plambeck, Kristopher E; Stern-Bach, Yael; Silverman, Jill L; Crawley, Jacqueline N; Hell, Johannes W; Díaz, Elva Cell reports. 29490264 2018 Feb 27;
Unexplored therapeutic opportunities in the human genome. Oprea, Tudor I; Bologa, Cristian G; Brunak, Søren; Campbell, Allen; Gan, Gregory N; Gaulton, Anna; Gomez, Shawn M; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L; Karlson, Anneli; Leach, Andrew R; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Stephen L; McManus, Michael T; Meehan, Terrence F; von Mering, Christian; Muthas, Daniel; Nguyen, Dac-Trung; Overington, John P; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L; Schürer, Stephan C; Simeonov, Anton; Sklar, Larry A; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Du?ica; Waller, Anna; Westergaard, David; Yang, Jeremy J; Zahoránszky-Köhalmi, Gergely Nature reviews. Drug discovery. 29472638 2018 May;
Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic Angiogenesis. Fan, Yanbo; Lu, Haocheng; Liang, Wenying; Garcia-Barrio, Minerva T; Guo, Yanhong; Zhang, Ji; Zhu, Tianqing; Hao, Yibai; Zhang, Jifeng; Chen, Y Eugene Circulation research. 29467198 2018 Mar 30;
Correction to: Characterization of bone morphology in CCN5/WISP2 knockout mice. Jiang, Jie; Zhao, Gexin; Lyons, Karen M Journal of cell communication and signaling. 29455304 2018 Mar;
Targeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid Arthritis. Tanner, Mark R; Pennington, Michael W; Chamberlain, Brayden H; Huq, Redwan; Gehrmann, Elizabeth J; Laragione, Teresina; Gulko, Pércio S; Beeton, Christine The Journal of pharmacology and experimental therapeutics. 29453198 2018 May;
A Seminiferous Tubule Squash Technique for the Cytological Analysis of Spermatogenesis Using the Mouse Model. Wellard, Stephen R; Hopkins, Jessica; Jordan, Philip W Journal of visualized experiments : JoVE 29443055 2018 02 06
Family with sequence similarity 13, member A modulates adipocyte insulin signaling and preserves systemic metabolic homeostasis. Wardhana, Donytra Arby; Ikeda, Koji; Barinda, Agian Jeffilano; Nugroho, Dhite Bayu; Qurania, Kikid Rucira; Yagi, Keiko; Miyata, Keishi; Oike, Yuichi; Hirata, Ken-Ichi; Emoto, Noriaki Proceedings of the National Academy of Sciences of the United States of America. 29386390 2018 02 13;
Phenotyping acute and chronic atopic dermatitis-like lesions in Stat6VT mice identifies a role for IL-33 in disease pathogenesis. DaSilva-Arnold, Sonia C; Thyagarajan, Anita; Seymour, Leroy J; Yi, Qiaofang; Bradish, Joshua R; Al-Hassani, Mohammed; Zhou, Hongming; Perdue, Nikolajs J; Nemeth, Val; Krbanjevic, Aleksandar; Serezani, Ana P M; Olson, Matthew R; Spandau, Dan F; Travers, Jeffrey B; Kaplan, Mark H; Turner, Matthew J Archives of dermatological research. 29368135 2018 Apr;
Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershäuser, Monja; Brommage, Robert; Meehan, Terrence F; Mason, Jeremy; Haselimashhadi, Hamed; IMPC Consortium; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J; White, Jacqueline K; Sorg, Tania; Champy, Marie-France; Bower, Lynette R; Reynolds, Corey L; Flenniken, Ann M; Murray, Stephen A; Nutter, Lauryl M J; Svenson, Karen L; West, David; Tocchini-Valentini, Glauco P; Beaudet, Arthur L; Bosch, Fatima; Braun, Robert B; Dobbie, Michael S; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A; Kent Lloyd, K C; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D; Tschöp, Matthias H; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas; Hrabe de Angelis, Martin Nature communications. 29348434 2018 Jan 18;
Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis. Regensburger, Martin; Prots, Iryna; Reimer, Dorothea; Brachs, Sebastian; Loskarn, Sandra; Lie, Dieter Chichung; Mielenz, Dirk; Winner, Beate Stem cell reports. 29337116 2018 02 13;
A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice. Abdelhamed, Zakia; Vuong, Shawn M; Hill, Lauren; Shula, Crystal; Timms, Andrew; Beier, David; Campbell, Kenneth; Mangano, Francesco T; Stottmann, Rolf W; Goto, June Development (Cambridge, England). 29317443 2018 01 09;
Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice. Kidana, Kiwami; Tatebe, Takuya; Ito, Kaori; Hara, Norikazu; Kakita, Akiyoshi; Saito, Takashi; Takatori, Sho; Ouchi, Yasuyoshi; Ikeuchi, Takeshi; Makino, Mitsuhiro; Saido, Takaomi C; Akishita, Masahiro; Iwatsubo, Takeshi; Hori, Yukiko; Tomita, Taisuke EMBO molecular medicine. 29311134 2018 03;
Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population. Huang, Lei; Wu, Kuo-Ho; Zhang, Liyong; Wang, Qinchuan; Tang, Shuangbo; Wu, Qiuping; Jiang, Pei-Hsiu; Lin, Jim Jung-Ching; Guo, Jian; Wang, Lin; Loh, Shih-Hurng; Cheng, Jianding Journal of the American Heart Association. 29306897 2018 01 06;
Robust model-based analysis of single-particle tracking experiments with Spot-On. Hansen, Anders S; Woringer, Maxime; Grimm, Jonathan B; Lavis, Luke D; Tjian, Robert; Darzacq, Xavier eLife. 29300163 2018 Jan 04;
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CRIPT exonic deletion and a novel missense mutation in a female with short stature, dysmorphic features, microcephaly, and pigmentary abnormalities. Leduc, Magalie S; Niu, Zhiyv; Bi, Weimin; Zhu, Wenmiao; Miloslavskaya, Irene; Chiang, Theodore; Streff, Haley; Seavitt, John R; Murray, Stephen A; Eng, Christine; Chan, Audrey; Yang, Yaping; Lalani, Seema R American journal of medical genetics. Part A. 27250922 2016 Aug;
Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy. Madeo, Marianna; Stewart, Michelle; Sun, Yuyang; Sahir, Nadia; Wiethoff, Sarah; Chandrasekar, Indra; Yarrow, Anna; Rosenfeld, Jill A; Yang, Yaping; Cordeiro, Dawn; McCormick, Elizabeth M; Muraresku, Colleen C; Jepperson, Tyler N; McBeth, Lauren J; Seidahmed, Mohammed Zain; El Khashab, Heba Y; Hamad, Muddathir; Azzedine, Hamid; Clark, Karl; Corrochano, Silvia; Wells, Sara; Elting, Mariet W; Weiss, Marjan M; Burn, Sabrina; Myers, Angela; Landsverk, Megan; Crotwell, Patricia L; Waisfisz, Quinten; Wolf, Nicole I; Nolan, Patrick M; Padilla-Lopez, Sergio; Houlden, Henry; Lifton, Richard; Mane, Shrikant; Singh, Brij B; Falk, Marni J; Mercimek-Mahmutoglu, Saadet; Bilguvar, Kaya; Salih, Mustafa A; Acevedo-Arozena, Abraham; Kruer, Michael C American journal of human genetics. 27236917 2016 Jun 2;
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Rapid, noninvasive quantitation of skin disease in systemic sclerosis using optical coherence elastography. Du, Yong; Liu, Chih-Hao; Lei, Ling; Singh, Manmohan; Li, Jiasong; Hicks, M John; Larin, Kirill V; Mohan, Chandra Journal of biomedical optics. 27048877 2016 Apr 30;
Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice. Shaheen, Ranad; Anazi, Shams; Ben-Omran, Tawfeg; Seidahmed, Mohammed Zain; Caddle, L Brianna; Palmer, Kristina; Ali, Rehab; Alshidi, Tarfa; Hagos, Samya; Goodwin, Leslie; Hashem, Mais; Wakil, Salma M; Abouelhoda, Mohamed; Colak, Dilek; Murray, Stephen A; American journal of human genetics. 27018474 2016 Apr 7;
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Optical coherence tomography as a tool for real-time visual feedback and biomechanical assessment of dermal filler injections: preliminary results in a pig skin model. Singh, Manmohan; Wang, Shang; Yee, Richard W; Larin, Kirill V Experimental dermatology. 26910121 2016 06;
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Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. West, David B; Engelhard, Eric K; Adkisson, Michael; Nava, A J; Kirov, Julia V; Cipollone, Andreanna; Willis, Brandon; Rapp, Jared; de Jong, Pieter J; Lloyd, Kent C PLoS genetics. 26839965 2016 Feb;
Classifying murine glomerulonephritis using optical coherence tomography and optical coherence elastography. Liu, Chih-Hao; Du, Yong; Singh, Manmohan; Wu, Chen; Han, Zhaolong; Li, Jiasong; Chang, Anthony; Mohan, Chandra; Larin, Kirill V Journal of biophotonics. 26791097 2016 Aug;
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Direct four-dimensional structural and functional imaging of cardiovascular dynamics in mouse embryos with 1.5 MHz optical coherence tomography. Wang, Shang; Singh, Manmohan; Lopez 3rd, Andrew L; Wu, Chen; Raghunathan, Raksha; Schill, Alexander; Li, Jiasong; Larin, Kirill V; Larina, Irina V Optics letters. 26469621 2015 Oct 15;
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A gene expression resource generated by genome-wide lacZ profiling in the mouse. Tuck, Elizabeth; Estabel, Jeanne; Oellrich, Anika; Maguire, Anna Karin; Adissu, Hibret A; Souter, Luke; Siragher, Emma; Lillistone, Charlotte; Green, Angela L; Wardle-Jones, Hannah; Carragher, Damian M; Karp, Natasha A; Smedley, Damian; Adams, Niels C; Sa Disease models & mechanisms. 26398943 2015 Nov;
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A mouse informatics platform for phenotypic and translational discovery. Ring, Natalie; Meehan, Terrence F; Blake, Andrew; Brown, James; Chen, Chao-Kung; Conte, Nathalie; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Jacobsen, Julius O B; Karp, Natasha; Lawson, Thomas; Mason, Jeremy C; Matthews, Peter; Morgan, Hugh; Relac, Mi Mammalian genome : official journal of the International Mammalian Genome Society. 26314589 2015 Oct;
In vivo micro-scale tomography of ciliary behavior in the mammalian oviduct. Wang, Shang; Burton, Jason C; Behringer, Richard R; Larina, Irina V Scientific reports. 26279472 2015;
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Comparative visualization of genotype-phenotype relationships. Yaikhom, Gagarine; Morgan, Hugh; Sneddon, Duncan; Retha, Ahmad; Atienza-Herrero, Julian; Blake, Andrew; Brown, James; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Ring, Natalie; Santos, Luis; Westerberg, Henrik; Brown, Steve D M; Mallon, Ann-Marie Nature methods. 26226357 2015 Aug;
Principles and application of LIMS in mouse clinics. Maier, Holger; Schütt, Christine; Steinkamp, Ralph; Hurt, Anja; Schneltzer, Elida; Gormanns, Philipp; Lengger, Christoph; Griffiths, Mark; Melvin, David; Agrawal, Neha; Alcantara, Rafael; Evans, Arthur; Gannon, David; Holroyd, Simon; Kipp, Christian; Raj, Mammalian genome : official journal of the International Mammalian Genome Society. 26208973 2015 Oct;
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High-resolution three-dimensional in vivo imaging of mouse oviduct using optical coherence tomography. Burton, Jason C; Wang, Shang; Stewart, C Allison; Behringer, Richard R; Larina, Irina V Biomedical optics express. 26203393 2015 Jul 1;
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Analysis of the effects of curvature and thickness on elastic wave velocity in cornea-like structures by finite element modeling and optical coherence elastography. Han, Zhaolong; Li, Jiasong; Singh, Manmohan; Aglyamov, Salavat R; Wu, Chen; Liu, Chih-Hao; Larin, Kirill V Applied physics letters. 26130825 2015 Jun 08;
Disease insights through cross-species phenotype comparisons. Haendel, Melissa A; Vasilevsky, Nicole; Brush, Matthew; Hochheiser, Harry S; Jacobsen, Julius; Oellrich, Anika; Mungall, Christopher J; Washington, Nicole; Köhler, Sebastian; Lewis, Suzanna E; Robinson, Peter N; Smedley, Damian Mammalian genome : official journal of the International Mammalian Genome Society. 26092691 2015 Oct;
Reproducibility: use mouse biobanks or lose them. Lloyd, Kent; Franklin, Craig; Lutz, Cat; Magnuson, Terry Nature. 26062496 2015 Jun 11;
Phase-sensitive optical coherence elastography at 1.5 million A-Lines per second. Singh, Manmohan; Wu, Chen; Liu, Chih-Hao; Li, Jiasong; Schill, Alexander; Nair, Achuth; Larin, Kirill V Optics letters. 26030564 2015 Jun 1;
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Quantitative methods for reconstructing tissue biomechanical properties in optical coherence elastography: a comparison study. Han, Zhaolong; Li, Jiasong; Singh, Manmohan; Wu, Chen; Liu, Chih-hao; Wang, Shang; Idugboe, Rita; Raghunathan, Raksha; Sudheendran, Narendran; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill V Physics in medicine and biology. 25860076 2015 May 7;
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Algorithms for improved 3-D reconstruction of live mammalian embryo vasculature from optical coherence tomography data. Kulkarni, Prathamesh M; Rey-Villamizar, Nicolas; Merouane, Amine; Sudheendran, Narendran; Wang, Shang; Garcia, Monica; Larina, Irina V; Roysam, Badrinath; Larin, Kirill V Quantitative imaging in medicine and surgery. 25694962 2015 Feb;
Quantitative assessment of corneal viscoelasticity using optical coherence elastography and a modified Rayleigh-Lamb equation. Han, Zhaolong; Aglyamov, Salavat R; Li, Jiasong; Singh, Manmohan; Wang, Shang; Vantipalli, Srilatha; Wu, Chen; Liu, Chih-Hao; Twa, Michael D; Larin, Kirill V Journal of biomedical optics. 25649624 2015 Feb;
Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds. Yang, Jie; Wang, Shih-Kai; Choi, Murim; Reid, Bryan M; Hu, Yuanyuan; Lee, Yuan-Ling; Herzog, Curtis R; Kim-Berman, Hera; Lee, Moses; Benke, Paul J; Lloyd, K C Kent; Simmer, James P; Hu, Jan C-C Molecular genetics & genomic medicine. 25629078 2015 Jan;
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Differentiating untreated and cross-linked porcine corneas of the same measured stiffness with optical coherence elastography. Li, Jiasong; Han, Zhaolong; Singh, Manmohan; Twa, Michael D; Larin, Kirill V Journal of biomedical optics. 25408955 2014 Nov;
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