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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Authors Journal PubMedID Publication Date
Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity. Peterson, Kevin A; Khalouei, Sam; Hanafi, Nour; Wood, Joshua A; Lanza, Denise G; Lintott, Lauri G; Willis, Brandon J; Seavitt, John R; Braun, Robert E; Dickinson, Mary E; White, Jacqueline K; Lloyd, K C Kent; Heaney, Jason D; Murray, Stephen A; Ramani, Arun; Nutter, Lauryl M J Communications biology 37301944 2023 Jun 10
Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice. Oestereicher, Manuela A; Wotton, Janine M; Ayabe, Shinya; Bou About, Ghina; Cheng, Tsz Kwan; Choi, Jae-Hoon; Clary, Dave; Dew, Emily M; Elfertak, Lahcen; Guimond, Alain; Haseli Mashhadi, Hamed; Heaney, Jason D; Kelsey, Lois; Keskivali-Bond, Piia; Lopez Gomez, Federico; Marschall, Susan; McFarland, Michael; Meziane, Hamid; Munoz Fuentes, Violeta; Nam, Ki-Hoan; Nichtová, Zuzana; Pimm, Dale; Bower, Lynette; Prochazka, Jan; Rozman, Jan; Santos, Luis; Stewart, Michelle; Tanaka, Nobuhiko; Ward, Christopher S; Willett, Amelia M E; Wilson, Robert; Braun, Robert E; Dickinson, Mary E; Flenniken, Ann M; Herault, Yann; Lloyd, K C Kent; Mallon, Ann-Marie; McKerlie, Colin; Murray, Stephen A; Nutter, Lauryl M J; Sedlacek, Radislav; Seong, Je Kyung; Sorg, Tania; Tamura, Masaru; Wells, Sara; Schneltzer, Elida; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; White, Jacqueline K; Spielmann, Nadine Mammalian genome : official journal of the International Mammalian Genome Society 37294348 2023 Jun
Topologically associating domain boundaries are required for normal genome function. Rajderkar, Sudha; Barozzi, Iros; Zhu, Yiwen; Hu, Rong; Zhang, Yanxiao; Li, Bin; Alcaina Caro, Ana; Fukuda-Yuzawa, Yoko; Kelman, Guy; Akeza, Adyam; Blow, Matthew J; Pham, Quan; Harrington, Anne N; Godoy, Janeth; Meky, Eman M; von Maydell, Kianna; Hunter, Riana D; Akiyama, Jennifer A; Novak, Catherine S; Plajzer-Frick, Ingrid; Afzal, Veena; Tran, Stella; Lopez-Rios, Javier; Talkowski, Michael E; Lloyd, K C Kent; Ren, Bing; Dickel, Diane E; Visel, Axel; Pennacchio, Len A Communications biology 37081156 2023 Apr 20
Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a NO-CCL2-CCR2 pathway. Ye, Qi; Jo, Juyeon; Wang, Chih-Yen; Oh, Heavin; Choy, Tiffany J; Kim, Kyoungin; Dâ Alessandro, Angelo; Reshetnyak, Yana K; Jung, Sung Yun; Chen, Zheng; Marrelli, Sean P; Lee, Hyun Kyoung bioRxiv : the preprint server for biology 37066295 2023 Apr 03
Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state. Yu, Wangie; Chen, Yunyun; Putluri, Nagireddy; Osman, Abdullah; Coarfa, Cristian; Putluri, Vasanta; Kamal, Abu H M; Asmussen, Jennifer Kay; Katsonis, Panagiotis; Myers, Jeffrey N; Lai, Stephen Y; Lu, Wuhao; Stephan, Clifford C; Powell, Reid T; Johnson, Faye M; Skinner, Heath D; Kazi, Jawad; Ahmed, Kazi Mokim; Hu, Linghao; Threet, Addison; Meyer, Matthew D; Bankson, James A; Wang, Tony; Davis, Jack; Parker, Kirby R; Harris, Madison A; Baek, Mokryun L; Echeverria, Gloria V; Qi, Xiaoli; Wang, Jin; Frederick, Andy I; Walsh, Alex J; Lichtarge, Olivier; Frederick, Mitchell J; Sandulache, Vlad C British journal of cancer 37012319 2023 Jun
The role of Limch1 alternative splicing in skeletal muscle function. Penna, Matthew S; Hu, Rong-Chi; Rodney, George G; Cooper, Thomas A Life science alliance 36977593 2023 Jun
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation. Elliott, Kelsey H; Balchand, Sai K; Bonatto Paese, Christian Louis; Chang, Ching-Fang; Yang, Yanfen; Brown, Kari M; Rasicci, Daniel T; He, Hao; Thorner, Konrad; Chaturvedi, Praneet; Murray, Stephen A; Chen, Jing; Porollo, Aleksey; Peterson, Kevin A; Brugmann, Samantha A Development (Cambridge, England) 36971348 2023 Apr 15
Essential genes: a cross-species perspective. Cacheiro, Pilar; Smedley, Damian Mammalian genome : official journal of the International Mammalian Genome Society 36897351 2023 Mar 10
Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease. Jones, Kathryn M; Mangin, Elise N; Reynolds, Corey L; Villanueva, Liliana E; Cruz, Julio Vladimir; Versteeg, Leroy; Keegan, Brian; Kendricks, April; Pollet, Jeroen; Gusovsky, Fabian; Bottazzi, Maria Elena; Hotez, Peter J Frontiers in cellular and infection microbiology 36844399 2023
Knockout mice are an important tool for human monogenic heart disease studies. Cacheiro, Pilar; Spielmann, Nadine; Mashhadi, Hamed Haseli; Fuchs, Helmut; Gailus-Durner, Valerie; Smedley, Damian; de Angelis, Martin Hrabĕ Disease models & mechanisms 36825469 2023 May 01
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development. Chee, Justine M; Lanoue, Louise; Clary, Dave; Higgins, Kendall; Bower, Lynette; Flenniken, Ann; Guo, Ruolin; Adams, David J; Bosch, Fatima; Braun, Robert E; Brown, Steve D M; Chin, H-J Genie; Dickinson, Mary E; Hsu, Chih-Wei; Dobbie, Michael; Gao, Xiang; Galande, Sanjeev; Grobler, Anne; Heaney, Jason D; Herault, Yann; de Angelis, Martin Hrabe; Mammano, Fabio; Nutter, Lauryl M J; Parkinson, Helen; Qin, Chuan; Shiroishi, Toshi; Sedlacek, Radislav; Seong, J-K; Xu, Ying; International Mouse Phenotyping Consortium; Brooks, Brian; McKerlie, Colin; Lloyd, K C Kent; Westerberg, Henrik; Moshiri, Ala BMC biology 36737727 2023 Feb 03
A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis. Wang, Yuqing; Zhu, Duolong; Ortiz-Velez, Laura C; Perry, Jacob L; Pennington, Michael W; Hyser, Joseph M; Britton, Robert A; Beeton, Christine Proceedings of the National Academy of Sciences of the United States of America 36595694 2023 Jan 10
Three-dimensional microCT imaging of mouse heart development from early post-implantation to late fetal stages. Li-Villarreal, Nanbing; Rasmussen, Tara L; Christiansen, Audrey E; Dickinson, Mary E; Hsu, Chih-Wei Mammalian genome : official journal of the International Mammalian Genome Society 36595063 2023 Jan 03
Dysregulated systemic metabolism in a Down syndrome mouse model. Sarver, Dylan C; Xu, Cheng; Velez, Leandro M; Aja, Susan; Jaffe, Andrew E; Seldin, Marcus M; Reeves, Roger H; Wong, G William Molecular metabolism 36587842 2023 Feb
A novel model of gestational diabetes: Acute high fat high sugar diet results in insulin resistance and beta cell dysfunction during pregnancy in mice. Mishra, Akansha; Ruano, Simone Hernandez; Saha, Pradip K; Pennington, Kathleen A PloS one 36520818 2022
Sex differences in allometry for phenotypic traits in mice indicate that females are not scaled males. Wilson, Laura A B; Zajitschek, Susanne R K; Lagisz, Malgorzata; Mason, Jeremy; Haselimashhadi, Hamed; Nakagawa, Shinichi Nature communications 36509767 2022 Dec 12
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes. Higgins, Kendall; Moore, Bret A; Berberovic, Zorana; Adissu, Hibret A; Eskandarian, Mohammad; Flenniken, Ann M; Shao, Andy; Imai, Denise M; Clary, Dave; Lanoue, Louise; Newbigging, Susan; Nutter, Lauryl M J; Adams, David J; Bosch, Fatima; Braun, Robert E; Brown, Steve D M; Dickinson, Mary E; Dobbie, Michael; Flicek, Paul; Gao, Xiang; Galande, Sanjeev; Grobler, Anne; Heaney, Jason D; Herault, Yann; de Angelis, Martin Hrabe; Chin, Hsian-Jean Genie; Mammano, Fabio; Qin, Chuan; Shiroishi, Toshihiko; Sedlacek, Radislav; Seong, J-K; Xu, Ying; IMPC Consortium; Lloyd, K C Kent; McKerlie, Colin; Moshiri, Ala Scientific reports 36456625 2022 Dec 01
Neuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina. Jiang, Danye; Burger, Courtney A; Akhanov, Viktor; Liang, Justine H; Mackin, Robert D; Albrecht, Nicholas E; Andrade, Pilar; Schafer, Dorothy P; Samuel, Melanie A Immunity 36379210 2022 Dec 13
The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource. Sollis, Elliot; Mosaku, Abayomi; Abid, Ala; Buniello, Annalisa; Cerezo, Maria; Gil, Laurent; Groza, Tudor; Güneş, Osman; Hall, Peggy; Hayhurst, James; Ibrahim, Arwa; Ji, Yue; John, Sajo; Lewis, Elizabeth; MacArthur, Jacqueline A L; McMahon, Aoife; Osumi-Sutherland, David; Panoutsopoulou, Kalliope; Pendlington, Zoë; Ramachandran, Santhi; Stefancsik, Ray; Stewart, Jonathan; Whetzel, Patricia; Wilson, Robert; Hindorff, Lucia; Cunningham, Fiona; Lambert, Samuel A; Inouye, Michael; Parkinson, Helen; Harris, Laura W Nucleic acids research 36350656 2022 Nov 09
The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease. Groza, Tudor; Gomez, Federico Lopez; Mashhadi, Hamed Haseli; Muñoz-Fuentes, Violeta; Gunes, Osman; Wilson, Robert; Cacheiro, Pilar; Frost, Anthony; Keskivali-Bond, Piia; Vardal, Bora; McCoy, Aaron; Cheng, Tsz Kwan; Santos, Luis; Wells, Sara; Smedley, Damian; Mallon, Ann-Marie; Parkinson, Helen Nucleic acids research 36305825 2022 Oct 28
Baat Gene Knockout Alters Post-Natal Development, the Gut Microbiome, and Reveals Unusual Bile Acids in Mice. Neugebauer, Kerri A; Okros, Maxwell; Guzior, Douglas V; Feiner, Jeremiah; Chargo, Nicholas J; Rzepka, Madison; Schilmiller, Anthony L; O'Reilly, Sandra; Jones, A Daniel; Watson, Victoria E; Luyendyk, James P; McCabe, Laura R; Quinn, Robert A Journal of lipid research 36243101 2022 Dec
Mendelian gene identification through mouse embryo viability screening. Cacheiro, Pilar; Westerberg, Carl Henrik; Mager, Jesse; Dickinson, Mary E; Nutter, Lauryl M J; Muñoz-Fuentes, Violeta; Hsu, Chih-Wei; Van den Veyver, Ignatia B; Flenniken, Ann M; McKerlie, Colin; Murray, Stephen A; Teboul, Lydia; Heaney, Jason D; Lloyd, K C Kent; Lanoue, Louise; Braun, Robert E; White, Jacqueline K; Creighton, Amie K; Laurin, Valerie; Guo, Ruolin; Qu, Dawei; Wells, Sara; Cleak, James; Bunton-Stasyshyn, Rosie; Stewart, Michelle; Harrisson, Jackie; Mason, Jeremy; Haseli Mashhadi, Hamed; Parkinson, Helen; Mallon, Ann-Marie; International Mouse Phenotyping Consortium; Genomics England Research Consortium; Smedley, Damian Genome medicine 36229886 2022 Oct 13
Promoting validation and cross-phylogenetic integration in model organism research. Cheng, Keith C; Burdine, Rebecca D; Dickinson, Mary E; Ekker, Stephen C; Lin, Alex Y; Lloyd, K C Kent; Lutz, Cathleen M; MacRae, Calum A; Morrison, John H; O'Connor, David H; Postlethwait, John H; Rogers, Crystal D; Sanchez, Susan; Simpson, Julie H; Talbot, William S; Wallace, Douglas C; Weimer, Jill M; Bellen, Hugo J Disease models & mechanisms 36125045 2022 09 01
Clinical exome sequencing uncovers a high frequency of Mendelian disorders in infants with stroke: A retrospective analysis. Kumar, Runjun D; Meng, Linyan; Liu, Pengfei; Miyake, Christina Y; Worley, Kim C; Bi, Weimin; Lalani, Seema R American journal of medical genetics. Part A 36065636 2022 Sep 06
Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects. Liang, Justine H; Alevy, Jonathan; Akhanov, Viktor; Seo, Ryan; Massey, Cory A; Jiang, Danye; Zhou, Joy; Sillitoe, Roy V; Noebels, Jeffrey L; Samuel, Melanie A Disease models & mechanisms 35972048 2022 09 01
Multivariate phenotype analysis enables genome-wide inference of mammalian gene function. Nicholson, George; Morgan, Hugh; Ganjgahi, Habib; Brown, Steve D M; Mallon, Ann-Marie; Holmes, Chris PLoS biology 35944064 2022 Aug
Phenotype-aware prioritisation of rare Mendelian disease variants. Kelly, Catherine; Szabo, Anita; Pontikos, Nikolas; Arno, Gavin; Robinson, Peter N; Jacobsen, Jules O B; Smedley, Damian; Cipriani, Valentina Trends in genetics : TIG 35934592 2022 Dec
Arap1 loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death. Shao, Andy; Lopez, Antonio Jacobo; Chen, JiaJia; Tham, Addy; Javier, Seanne; Quiroz, Alejandra; Frick, Sonia; Levine, Edward M; Lloyd, K C Kent; Leonard, Brian C; Murphy, Christopher J; Glaser, Thomas M; Moshiri, Ala Disease models & mechanisms 35758026 2022 Jul 01
Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer. Pulliam, Thomas L; Awad, Dominik; Han, Jenny J; Murray, Mollianne M; Ackroyd, Jeffrey J; Goli, Pavithr; Oakhill, Jonathan S; Scott, John W; Ittmann, Michael M; Frigo, Daniel E Cells 35741020 2022 06 10
Preventing Cholesterol-Induced Perk (Protein Kinase RNA-Like Endoplasmic Reticulum Kinase) Signaling in Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation. Chattopadhyay, Abhijnan; Guan, Pujun; Majumder, Suravi; Kaw, Kaveeta; Zhou, Zhen; Zhang, Chen; Prakash, Siddharth K; Kaw, Anita; Buja, L Maximillian; Kwartler, Callie S; Milewicz, Dianna M Arteriosclerosis, thrombosis, and vascular biology 35708026 2022 08
The GA4GH Phenopacket schema defines a computable representation of clinical data. Jacobsen, Julius O B; Baudis, Michael; Baynam, Gareth S; Beckmann, Jacques S; Beltran, Sergi; Buske, Orion J; Callahan, Tiffany J; Chute, Christopher G; Courtot, Mélanie; Danis, Daniel; Elemento, Olivier; Essenwanger, Andrea; Freimuth, Robert R; Gargano, Michael A; Groza, Tudor; Hamosh, Ada; Harris, Nomi L; Kaliyaperumal, Rajaram; Lloyd, Kevin C Kent; Khalifa, Aly; Krawitz, Peter M; Köhler, Sebastian; Laraway, Brian J; Lehväslaiho, Heikki; Matalonga, Leslie; McMurry, Julie A; Metke-Jimenez, Alejandro; Mungall, Christopher J; Munoz-Torres, Monica C; Ogishima, Soichi; Papakonstantinou, Anastasios; Piscia, Davide; Pontikos, Nikolas; Queralt-Rosinach, Núria; Roos, Marco; Sass, Julian; Schofield, Paul N; Seelow, Dominik; Siapos, Anastasios; Smedley, Damian; Smith, Lindsay D; Steinhaus, Robin; Sundaramurthi, Jagadish Chandrabose; Swietlik, Emilia M; Thun, Sylvia; Vasilevsky, Nicole A; Wagner, Alex H; Warner, Jeremy L; Weiland, Claus; GAGH Phenopacket Modeling Consortium; Haendel, Melissa A; Robinson, Peter N Nature biotechnology 35705716 2022 Jun
MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses. Devine, Jay; Vidal-García, Marta; Liu, Wei; Neves, Amanda; Lo Vercio, Lucas D; Green, Rebecca M; Richbourg, Heather A; Marchini, Marta; Unger, Colton M; Nickle, Audrey C; Radford, Bethany; Young, Nathan M; Gonzalez, Paula N; Schuler, Robert E; Bugacov, Alejandro; Rolian, Campbell; Percival, Christopher J; Williams, Trevor; Niswander, Lee; Calof, Anne L; Lander, Arthur D; Visel, Axel; Jirik, Frank R; Cheverud, James M; Klein, Ophir D; Birnbaum, Ramon Y; Merrill, Amy E; Ackermann, Rebecca R; Graf, Daniel; Hemberger, Myriam; Dean, Wendy; Forkert, Nils D; Murray, Stephen A; Westerberg, Henrik; Marcucio, Ralph S; Hallgrímsson, Benedikt Scientific data 35614082 2022 May 25
Evaluation of phenotype-driven gene prioritization methods for Mendelian diseases. Jacobsen, Julius O B; Kelly, Catherine; Cipriani, Valentina; Robinson, Peter N; Smedley, Damian Briefings in bioinformatics 35595299 2022 09 20
Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism. Stork, Brittany A; Dean, Adam; Ortiz, Andrea R; Saha, Pradip; Putluri, Nagireddy; Planas-Silva, Maricarmen D; Mahmud, Iqbal; Rajapakshe, Kimal; Coarfa, Cristian; Knapp, Stefan; Lorenzi, Philip L; Kemp, Bruce E; Turk, Benjamin E; Scott, John W; Means, Anthony R; York, Brian Molecular metabolism 35562082 2022 08
Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen. Wotton, Janine M; Peterson, Emma; Flenniken, Ann M; Bains, Rasneer S; Veeraragavan, Surabi; Bower, Lynette R; Bubier, Jason A; Parisien, Marc; Bezginov, Alexandr; Haselimashhadi, Hamed; Mason, Jeremy; Moore, Michayla A; Stewart, Michelle E; Clary, Dave A; Delbarre, Daniel J; Anderson, Laura C; D'Souza, Abigail; Goodwin, Leslie O; Harrison, Mark E; Huang, Ziyue; Mckay, Matthew; Qu, Dawei; Santos, Luis; Srinivasan, Subhiksha; Urban, Rachel; Vukobradovic, Igor; Ward, Christopher S; Willett, Amelia M; Braun, Robert E; Brown, Steve D M; Dickinson, Mary E; Heaney, Jason D; Kumar, Vivek; Lloyd, K C Kent; Mallon, Ann-Marie; McKerlie, Colin; Murray, Stephen A; Nutter, Lauryl M J; Parkinson, Helen; Seavitt, John R; Wells, Sara; Samaco, Rodney C; Chesler, Elissa J; Smedley, Damian; Diatchenko, Luda; Baumbauer, Kyle M; Young, Erin E; Bonin, Robert P; Mandillo, Silvia; White, Jacqueline K; International Mouse Phenotyping Consortium Pain 35552317 2022 Jun 01
Mouse mutagenesis and phenotyping to generate models of development and disease. Gridley, Thomas; Murray, Stephen A Current topics in developmental biology 35461561 2022
Phenotype-driven approaches to enhance variant prioritization and diagnosis of rare disease. Jacobsen, Julius O B; Kelly, Catherine; Cipriani, Valentina; Research Consortium, Genomics England; Mungall, Christopher J; Reese, Justin; Danis, Daniel; Robinson, Peter N; Smedley, Damian Human mutation 35391505 2022 Apr 07
Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism. Meng, Huan; Gonzales, Naomi M; Jung, Sung Yun; Lu, Yue; Putluri, Nagireddy; Zhu, Bokai; Dacso, Clifford C; Lonard, David M; O'Malley, Bert W Cell reports 35263593 2022 03 08
ADAD2 regulates heterochromatin in meiotic and post-meiotic male germ cells via translation of MDC1. Chukrallah, Lauren G; Badrinath, Aditi; Vittor, Gabrielle G; Snyder, Elizabeth M Journal of cell science 35191498 2022 02 15
LMOD2-related dilated cardiomyopathy presenting in late infancy. Lay, Erica; Azamian, Mahshid S; Denfield, Susan W; Dreyer, William; Spinner, Joseph A; Kearney, Debra; Zhang, Lilei; Worley, Kim C; Bi, Weimin; Lalani, Seema R American journal of medical genetics. Part A 35188328 2022 Feb 21
Making sense of the linear genome, gene function and TADs. Long, Helen S; Greenaway, Simon; Powell, George; Mallon, Ann-Marie; Lindgren, Cecilia M; Simon, Michelle M Epigenetics & chromatin 35090532 2022 01 29
Myocardial Rev-erb-Mediated Diurnal Metabolic Rhythm and Obesity Paradox. Song, Shiyang; Tien, Chih-Liang; Cui, Hao; Basil, Paul; Zhu, Ningxia; Gong, Yingyun; Li, Wenbo; Li, Hui; Fan, Qiying; Min Choi, Jong; Luo, Weijia; Xue, Yanfeng; Cao, Rui; Zhou, Wenjun; Ortiz, Andrea R; Stork, Brittany; Mundra, Vatsala; Putluri, Nagireddy; York, Brian; Chu, Maoping; Chang, Jiang; Yun Jung, Sung; Xie, Liang; Song, Jiangping; Zhang, Lilei; Sun, Zheng Circulation 35034472 2022 02 08
Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice. Wu, Yifan; Li, Evan; Knight, Morgan; Adeniyi-Ipadeola, Grace; Song, Li-Zhen; Burns, Alan R; Gazzinelli-Guimaraes, Ana Clara; Fujiwara, Ricardo; Bottazzi, Maria Elena; Weatherhead, Jill E PLoS neglected tropical diseases 34914687 2021 12
Dimensional reduction of phenotypes from 53 000 mouse models reveals a diverse landscape of gene function. Konopka, Tomasz; Vestito, Letizia; Smedley, Damian Bioinformatics advances 34870209 2021
100,000 Genomes Pilot on Rare-Disease Diagnosis in Health Care - Preliminary Report. 100,000 Genomes Project Pilot Investigators; Smedley, Damian; Smith, Katherine R; Martin, Antonio; Thomas, Ellen A; McDonagh, Ellen M; Cipriani, Valentina; Ellingford, Jamie M; Arno, Gavin; Tucci, Arianna; Vandrovcova, Jana; Chan, Georgia; Williams, Hywel J; Ratnaike, Thiloka; Wei, Wei; Stirrups, Kathleen; Ibanez, Kristina; Moutsianas, Loukas; Wielscher, Matthias; Need, Anna; Barnes, Michael R; Vestito, Letizia; Buchanan, James; Wordsworth, Sarah; Ashford, Sofie; Rehmström, Karola; Li, Emily; Fuller, Gavin; Twiss, Philip; Spasic-Boskovic, Olivera; Halsall, Sally; Floto, R Andres; Poole, Kenneth; Wagner, Annette; Mehta, Sarju G; Gurnell, Mark; Burrows, Nigel; James, Roger; Penkett, Christopher; Dewhurst, Eleanor; Gräf, Stefan; Mapeta, Rutendo; Kasanicki, Mary; Haworth, Andrea; Savage, Helen; Babcock, Melanie; Reese, Martin G; Bale, Mark; Baple, Emma; Boustred, Christopher; Brittain, Helen; de Burca, Anna; Bleda, Marta; Devereau, Andrew; Halai, Dina; Haraldsdottir, Eik; Hyder, Zerin; Kasperaviciute, Dalia; Patch, Christine; Polychronopoulos, Dimitris; Matchan, Angela; Sultana, Razvan; Ryten, Mina; Tavares, Ana L T; Tregidgo, Carolyn; Turnbull, Clare; Welland, Matthew; Wood, Suzanne; Snow, Catherine; Williams, Eleanor; Leigh, Sarah; Foulger, Rebecca E; Daugherty, Louise C; Niblock, Olivia; Leong, Ivone U S; Wright, Caroline F; Davies, Jim; Crichton, Charles; Welch, James; Woods, Kerrie; Abulhoul, Lara; Aurora, Paul; Bockenhauer, Detlef; Broomfield, Alexander; Cleary, Maureen A; Lam, Tanya; Dattani, Mehul; Footitt, Emma; Ganesan, Vijeya; Grunewald, Stephanie; Compeyrot-Lacassagne, Sandrine; Muntoni, Francesco; Pilkington, Clarissa; Quinlivan, Rosaline; Thapar, Nikhil; Wallis, Colin; Wedderburn, Lucy R; Worth, Austen; Bueser, Teofila; Compton, Cecilia; Deshpande, Charu; Fassihi, Hiva; Haque, Eshika; Izatt, Louise; Josifova, Dragana; Mohammed, Shehla; Robert, Leema; Rose, Sarah; Ruddy, Deborah; Sarkany, Robert; Say, Genevieve; Shaw, Adam C; Wolejko, Agata; Habib, Bishoy; Burns, Gavin; Hunter, Sarah; Grocock, Russell J; Humphray, Sean J; Robinson, Peter N; Haendel, Melissa; Simpson, Michael A; Banka, Siddharth; Clayton-Smith, Jill; Douzgou, Sofia; Hall, Georgina; Thomas, Huw B; O'Keefe, Raymond T; Michaelides, Michel; Moore, Anthony T; Malka, Sam; Pontikos, Nikolas; Browning, Andrew C; Straub, Volker; Gorman, Gráinne S; Horvath, Rita; Quinton, Richard; Schaefer, Andrew M; Yu-Wai-Man, Patrick; Turnbull, Doug M; McFarland, Robert; Taylor, Robert W; O'Connor, Emer; Yip, Janice; Newland, Katrina; Morris, Huw R; Polke, James; Wood, Nicholas W; Campbell, Carolyn; Camps, Carme; Gibson, Kate; Koelling, Nils; Lester, Tracy; Németh, Andrea H; Palles, Claire; Patel, Smita; Roy, Noemi B A; Sen, Arjune; Taylor, John; Cacheiro, Pilar; Jacobsen, Julius O; Seaby, Eleanor G; Davison, Val; Chitty, Lyn; Douglas, Angela; Naresh, Kikkeri; McMullan, Dom; Ellard, Sian; Temple, I Karen; Mumford, Andrew D; Wilson, Gill; Beales, Phil; Bitner-Glindzicz, Maria; Black, Graeme; Bradley, John R; Brennan, Paul; Burn, John; Chinnery, Patrick F; Elliott, Perry; Flinter, Frances; Houlden, Henry; Irving, Melita; Newman, William; Rahman, Shamima; Sayer, John A; Taylor, Jenny C; Webster, Andrew R; Wilkie, Andrew O M; Ouwehand, Willem H; Raymond, F Lucy; Chisholm, John; Hill, Sue; Bentley, David; Scott, Richard H; Fowler, Tom; Rendon, Augusto; Caulfield, Mark The New England journal of medicine 34758253 2021 11 11
Progress towards completing the mutant mouse null resource. Peterson, Kevin A; Murray, Stephen A Mammalian genome : official journal of the International Mammalian Genome Society 34698892 2021 Oct 26
A metabolome atlas of the aging mouse brain. Ding, Jun; Ji, Jian; Rabow, Zachary; Shen, Tong; Folz, Jacob; Brydges, Christopher R; Fan, Sili; Lu, Xinchen; Mehta, Sajjan; Showalter, Megan R; Zhang, Ying; Araiza, Renee; Bower, Lynette R; Lloyd, K C Kent; Fiehn, Oliver Nature communications 34654818 2021 10 15
PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes. Angelini, Aude; Saha, Pradip K; Jain, Antrix; Jung, Sung Yun; Mynatt, Randall L; Pi, Xinchun; Xie, Liang Cell reports 34610308 2021 10 05
Biology before the SOS Response-DNA Damage Mechanisms at Chromosome Fragile Sites. Fitzgerald, Devon M; Rosenberg, Susan M Cells 34571923 2021 09 01
Importing genetically altered animals: ensuring quality. Birling, M-C; Fray, M D; Kasparek, P; Kopkanova, J; Massimi, M; Matteoni, R; Montoliu, L; Nutter, L M J; Raspa, M; Rozman, J; Ryder, E J; Scavizzi, F; Voikar, V; Wells, S; Pavlovic, G; Teboul, L Mammalian genome : official journal of the International Mammalian Genome Society 34536110 2022 Mar
Pleiotropy data resource as a primer for investigating co-morbidities/multi-morbidities and their role in disease. Muñoz-Fuentes, Violeta; Haselimashhadi, Hamed; Santos, Luis; Westerberg, Henrik; Parkinson, Helen; Mason, Jeremy Mammalian genome : official journal of the International Mammalian Genome Society 34524473 2021 Sep 15
Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy. Hoffman, Kristyn A; Villar, Maria Jose; Poveda, Cristina; Bottazzi, Maria Elena; Hotez, Peter J; Tweardy, David J; Jones, Kathryn M Frontiers in cellular and infection microbiology 34504808 2021
Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Mao, Hua; Li, Luge; Fan, Qiying; Angelini, Aude; Saha, Pradip K; Coarfa, Cristian; Rajapakshe, Kimal; Perera, Dimuthu; Cheng, Jizhong; Wu, Huaizhu; Ballantyne, Christie M; Sun, Zheng; Xie, Liang; Pi, Xinchun Nature communications 34489478 2021 09 06
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes. Lana-Elola, Eva; Cater, Heather; Watson-Scales, Sheona; Greenaway, Simon; Müller-Winkler, Jennifer; Gibbins, Dorota; Nemes, Mihaela; Slender, Amy; Hough, Tertius; Keskivali-Bond, Piia; Scudamore, Cheryl L; Herbert, Eleanor; Banks, Gareth T; Mobbs, Helene; Canonica, Tara; Tosh, Justin; Noy, Suzanna; Llorian, Miriam; Nolan, Patrick M; Griffin, Julian L; Good, Mark; Simon, Michelle; Mallon, Ann-Marie; Wells, Sara; Fisher, Elizabeth M C; Tybulewicz, Victor L J Disease models & mechanisms 34477842 2021 Oct 01
COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay. Marom, Ronit; Burrage, Lindsay C; Venditti, Rossella; Clément, Aurélie; Blanco-Sánchez, Bernardo; Jain, Mahim; Scott, Daryl A; Rosenfeld, Jill A; Sutton, V Reid; Shinawi, Marwan; Mirzaa, Ghayda; DeVile, Catherine; Roberts, Rowenna; Calder, Alistair D; Allgrove, Jeremy; Grafe, Ingo; Lanza, Denise G; Li, Xiaohui; Joeng, Kyu Sang; Lee, Yi-Chien; Song, I-Wen; Sliepka, Joseph M; Batkovskyte, Dominyka; Washington, Megan; Dawson, Brian C; Jin, Zixue; Jiang, Ming-Ming; Chen, Shan; Chen, Yuqing; Tran, Alyssa A; Emrick, Lisa T; Murdock, David R; Hanchard, Neil A; Zapata, Gladys E; Mehta, Nitesh R; Weis, Mary Ann; Scott, Abbey A; Tremp, Brenna A; Phillips, Jennifer B; Wegner, Jeremy; Taylor-Miller, Tashunka; Gibbs, Richard A; Muzny, Donna M; Jhangiani, Shalini N; Hicks, John; Stottmann, Rolf W; Dickinson, Mary E; Seavitt, John R; Heaney, Jason D; Eyre, David R; Undiagnosed Diseases Network; Westerfield, Monte; De Matteis, Maria Antonietta; Lee, Brendan American journal of human genetics 34450031 2021 09 02
Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor. Huang, Yung-Hsin; Chen, Chun-Wei; Sundaramurthy, Venkatasubramaniam; Slabicki, Mikolaj; Hao, Dapeng; Watson, Caroline J; Tovy, Ayala; Reyes, Jaime M; Dakhova, Olga; Crovetti, Brielle R; Galonska, Christina; Lee, Minjung; Brunetti, Lorenzo; Zhou, Yubin; Tatton-Brown, Katrina; Huang, Yun; Cheng, Xiaodong; Meissner, Alexander; Valk, Peter J M; Van Maldergem, Lionel; Sanders, Mathijs A; Blundell, Jamie R; Li, Wei; Ebert, Benjamin L; Goodell, Margaret A Cancer discovery 34429321 2021 Aug 24
Diffusion enables integration of heterogeneous data and user-driven learning in a desktop knowledge-base. Konopka, Tomasz; Ng, Sandra; Smedley, Damian PLoS computational biology 34379637 2021 Aug
TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain. Kasembeli, Moses M; Singhmar, Pooja; Ma, Jiacheng; Edralin, Jules; Tang, Yongfu; Adams 3rd, Clydell; Heijnen, Cobi J; Kavelaars, Annemieke; Tweardy, David J Biochemical pharmacology 34274354 2021 Oct
Screening and validation of genome-edited animals. Bunton-Stasyshyn, Rosie K; Codner, Gemma F; Teboul, Lydia Laboratory animals 34192966 2022 Feb
A rare description of pure partial trisomy of 16q12.2q24.3 and review of the literature. Manor, Joshua; Dinu, Daniela; Azamian, Mahshid S; Bi, Weimin; Darilek, Sandra; Lalani, Seema R American journal of medical genetics. Part A 34061437 2021 Jun 01
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma. Mohammed, Yassene; Michaud, Sarah A; Pětrošová, Helena; Yang, Juncong; Ganguly, Milan; Schibli, David; Flenniken, Ann M; Nutter, Lauryl M J; Adissu, Hibret A; Lloyd, K C Kent; McKerlie, Colin; Borchers, Christoph H NPJ systems biology and applications 34050187 2021 May 28
REMBI: Recommended Metadata for Biological Images-enabling reuse of microscopy data in biology. Sarkans, Ugis; Chiu, Wah; Collinson, Lucy; Darrow, Michele C; Ellenberg, Jan; Grunwald, David; Hériché, Jean-Karim; Iudin, Andrii; Martins, Gabriel G; Meehan, Terry; Narayan, Kedar; Patwardhan, Ardan; Russell, Matthew Robert Geoffrey; Saibil, Helen R; Str Nature methods 34021280 2021 May 21
Rap1 in the VMH regulates glucose homeostasis. Kaneko, Kentaro; Lin, Hsiao-Yun; Fu, Yukiko; Saha, Pradip K; De la Puente-Gomez, Ana B; Xu, Yong; Ohinata, Kousaku; Chen, Peter; Morozov, Alexei; Fukuda, Makoto JCI insight 33974562 2021 Jun 08
Inter- and Transgenerational Effects of Paternal Exposure to Inorganic Arsenic. Gong, Yingyun; Xue, Yanfeng; Li, Xin; Zhang, Zhao; Zhou, Wenjun; Marcolongo, Paola; Benedetti, Angiolo; Mao, Shengyong; Han, Leng; Ding, Guolian; Sun, Zheng Advanced science (Weinheim, Baden-Wurttemberg, Germany) 33854880 2021 04
Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology. Hoffman, Kristyn; Liu, Zongyuan; Hossain, Ekram; Bottazzi, Maria Elena; Hotez, Peter J; Jones, Kathryn M; McCall, Laura-Isobel ACS infectious diseases 33843195 2021 06 11
A resource of targeted mutant mouse lines for 5,061 genes. Birling, Marie-Christine; Yoshiki, Atsushi; Adams, David J; Ayabe, Shinya; Beaudet, Arthur L; Bottomley, Joanna; Bradley, Allan; Brown, Steve D M; Bürger, Antje; Bushell, Wendy; Chiani, Francesco; Chin, Hsian-Jean Genie; Christou, Skevoulla; Codner, Gemma F; DeMayo, Francesco J; Dickinson, Mary E; Doe, Brendan; Donahue, Leah Rae; Fray, Martin D; Gambadoro, Alessia; Gao, Xiang; Gertsenstein, Marina; Gomez-Segura, Alba; Goodwin, Leslie O; Heaney, Jason D; Hérault, Yann; de Angelis, Martin Hrabe; Jiang, Si-Tse; Justice, Monica J; Kasparek, Petr; King, Ruairidh E; Kühn, Ralf; Lee, Ho; Lee, Young Jae; Liu, Zhiwei; Lloyd, K C Kent; Lorenzo, Isabel; Mallon, Ann-Marie; McKerlie, Colin; Meehan, Terrence F; Fuentes, Violeta Munoz; Newman, Stuart; Nutter, Lauryl M J; Oh, Goo Taeg; Pavlovic, Guillaume; Ramirez-Solis, Ramiro; Rosen, Barry; Ryder, Edward J; Santos, Luis A; Schick, Joel; Seavitt, John R; Sedlacek, Radislav; Seisenberger, Claudia; Seong, Je Kyung; Skarnes, William C; Sorg, Tania; Steel, Karen P; Tamura, Masaru; Tocchini-Valentini, Glauco P; Wang, Chi-Kuang Leo; Wardle-Jones, Hannah; Wattenhofer-Donzé, Marie; Wells, Sara; Wiles, Michael V; Willis, Brandon J; Wood, Joshua A; Wurst, Wolfgang; Xu, Ying; International Mouse Phenotyping Consortium (IMPC); Teboul, Lydia; Murray, Stephen A Nature genetics 33833456 2021 04
Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance. Mao, Hua; Li, Luge; Fan, Qiying; Angelini, Aude; Saha, Pradip K; Wu, Huaizhu; Ballantyne, Christie M; Hartig, Sean M; Xie, Liang; Pi, Xinchun Nature communications 33772019 2021 03 26
REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Ding, Guolian; Li, Xin; Hou, Xinguo; Zhou, Wenjun; Gong, Yingyun; Liu, Fuqiang; He, Yanlin; Song, Jia; Wang, Jing; Basil, Paul; Li, Wenbo; Qian, Sichong; Saha, Pradip; Wang, Jinbang; Cui, Chen; Yang, Tingting; Zou, Kexin; Han, Younghun; Amos, Christopher I; Xu, Yong; Chen, Li; Sun, Zheng Nature 33762728 2021 Apr
Genetic analysis of Pycr1 and Pycr2 in mice. Stum, Morgane G; Tadenev, Abigail L D; Seburn, Kevin L; Miers, Kathy E; Poon, Pak P; McMaster, Christopher R; Robinson, Carolyn; Kane, Coleen; Silva, Kathleen A; Cliften, Paul F; Sundberg, John P; Reinholdt, Laura G; John, Simon W M; Burgess, Robert W Genetics 33734376 2021 May 17
Overlapping roles for PLK1 and Aurora A during meiotic centrosome biogenesis in mouse spermatocytes. Wellard, Stephen R; Zhang, Yujiao; Shults, Chris; Zhao, Xueqi; McKay, Matthew; Murray, Stephen A; Jordan, Philip W EMBO reports 33615678 2021 Apr 07
LAMA: automated image analysis for the developmental phenotyping of mouse embryos. Horner, Neil R; Venkataraman, Shanmugasundaram; Armit, Chris; Casero, Ramón; Brown, James M; Wong, Michael D; van Eede, Matthijs C; Henkelman, R Mark; Johnson, Sara; Teboul, Lydia; Wells, Sara; Brown, Steve D; Westerberg, Henrik; Mallon, Ann-Marie Development (Cambridge, England) 33574040 2021 03 24
Reversible cardiac disease features in an inducible CUG repeat RNA-expressing mouse model of myotonic dystrophy. Rao, Ashish N; Campbell, Hannah M; Guan, Xiangnan; Word, Tarah A; Wehrens, Xander Ht; Xia, Zheng; Cooper, Thomas A JCI insight 33497365 2021 Mar 08
OpenStats: A robust and scalable software package for reproducible analysis of high-throughput phenotypic data. Haselimashhadi, Hamed; Mason, Jeremy C; Mallon, Ann-Marie; Smedley, Damian; Meehan, Terrence F; Parkinson, Helen PloS one 33378393 2020
Nitric oxide modulates bone anabolism through regulation of osteoblast glycolysis and differentiation. Jin, Zixue; Kho, Jordan; Dawson, Brian; Jiang, Ming-Ming; Chen, Yuqing; Ali, Saima; Burrage, Lindsay C; Grover, Monica; Palmer, Donna J; Turner, Dustin L; Ng, Philip; Nagamani, Sandesh Cs; Lee, Brendan The Journal of clinical investigation 33373331 2021 Mar 01
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density. Swan, Anna L; Schütt, Christine; Rozman, Jan; Del Mar Muñiz Moreno, Maria; Brandmaier, Stefan; Simon, Michelle; Leuchtenberger, Stefanie; Griffiths, Mark; Brommage, Robert; Keskivali-Bond, Piia; Grallert, Harald; Werner, Thomas; Teperino, Raffaele; Becker, Lore; Miller, Gregor; Moshiri, Ala; Seavitt, John R; Cissell, Derek D; Meehan, Terrence F; Acar, Elif F; Lelliott, Christopher J; Flenniken, Ann M; Champy, Marie-France; Sorg, Tania; Ayadi, Abdel; Braun, Robert E; Cater, Heather; Dickinson, Mary E; Flicek, Paul; Gallegos, Juan; Ghirardello, Elena J; Heaney, Jason D; Jacquot, Sylvie; Lally, Connor; Logan, John G; Teboul, Lydia; Mason, Jeremy; Spielmann, Nadine; McKerlie, Colin; Murray, Stephen A; Nutter, Lauryl M J; Odfalk, Kristian F; Parkinson, Helen; Prochazka, Jan; Reynolds, Corey L; Selloum, Mohammed; Spoutil, Frantisek; Svenson, Karen L; Vales, Taylor S; Wells, Sara E; White, Jacqueline K; Sedlacek, Radislav; Wurst, Wolfgang; Lloyd, K C Kent; Croucher, Peter I; Fuchs, Helmut; Williams, Graham R; Bassett, J H Duncan; Gailus-Durner, Valerie; Herault, Yann; Mallon, Ann-Marie; Brown, Steve D M; Mayer-Kuckuk, Philipp; Hrabe de Angelis, Martin; IMPC Consortium PLoS genetics 33370286 2020 Dec
Vertical transmission of a large calvarial ossification defect due to heterozygous variants of ALX4 and TWIST1. Walters, Michelle E; Lacassie, Yves; Azamian, Mahshid; Franciskovich, Rachel; Zapata, Gladys; Hernandez, Patricia P; Liu, Pengfei; Campbell, Ian M; Bostwick, Bret L; Lalani, Seema R American journal of medical genetics. Part A 33369125 2021 Mar
XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis. Meng, Huan; Gonzales, Naomi M; Lonard, David M; Putluri, Nagireddy; Zhu, Bokai; Dacso, Clifford C; York, Brian; O'Malley, Bert W Nature communications. 33277471 2020 12 04;
Cage-lid hanging behavior as a translationally relevant measure of pain in mice. Zhang, Hantao; Lecker, Irene; Collymore, Chereen; Dokova, Anastassia; Pham, Maian Christine; Rosen, Sarah F; Crawhall-Duk, Hayley; Zain, Maham; Valencia, Megan; Filippini, Helena Fetter; Li, Jerry; D'Souza, Abigail J; Cho, Chulmin; Michailidis, Vassilia; Whissell, Paul D; Patel, Ingita; Steenland, Hendrik W; Virginia Lee, Wai-Jane; Moayedi, Massieh; Sterley, Toni-Lee; Bains, Jaideep S; Stratton, Jo Anne; Matyas, John R; Biernaskie, Jeff; Dubins, David; Vukobradovic, Igor; Bezginov, Alexandr; Flenniken, Ann M; Martin, Loren J; Mogil, Jeffrey S; Bonin, Robert P Pain 33230005 2021 05 01
Snx3 is important for mammalian neural tube closure via its role in canonical and non-canonical WNT signaling. Brown, Heather Mary; Murray, Stephen A; Northrup, Hope; Au, Kit Sing; Niswander, Lee A Development (Cambridge, England) 33214242 2020 11 19
Sexual dimorphism in trait variability and its eco-evolutionary and statistical implications. Zajitschek, Susanne Rk; Zajitschek, Felix; Bonduriansky, Russell; Brooks, Robert C; Cornwell, Will; Falster, Daniel S; Lagisz, Malgorzata; Mason, Jeremy; Senior, Alistair M; Noble, Daniel Wa; Nakagawa, Shinichi eLife. 33198888 2020 11 17;
Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia. Ward, Christopher S; Huang, Teng-Wei; Herrera, Jose A; Samaco, Rodney C; McGraw, Christopher M; Parra, Diana E; Arvide, E Melissa; Ito-Ishida, Aya; Meng, Xiangling; Ure, Kerstin; Zoghbi, Huda Y; Neul, Jeffrey L Frontiers in neurology. 33193060 2020;
Aurora B and C kinases regulate chromosome desynapsis and segregation during mouse and human spermatogenesis. Wellard, Stephen R; Schindler, Karen; Jordan, Philip W Journal of cell science 33172986 2020 12 04
A holistic view of mouse enhancer architectures reveals analogous pleiotropic effects and correlation with human disease. Sethi, Siddharth; Vorontsov, Ilya E; Kulakovskiy, Ivan V; Greenaway, Simon; Williams, John; Makeev, Vsevolod J; Brown, Steve D M; Simon, Michelle M; Mallon, Ann-Marie BMC genomics. 33138777 2020 Nov 02;
Antioxidant Carbon Nanoparticles Inhibit Fibroblast-Like Synoviocyte Invasiveness and Reduce Disease Severity in a Rat Model of Rheumatoid Arthritis. Tanner, Mark R; Huq, Redwan; Sikkema, William K A; Nilewski, Lizanne G; Yosef, Nejla; Schmitt, Cody; Flores-Suarez, Carlos P; Raugh, Arielle; Laragione, Teresina; Gulko, Pércio S; Tour, James M; Beeton, Christine Antioxidants (Basel, Switzerland) 33081234 2020 Oct 16
Anticipating and Identifying Collateral Damage in Genome Editing. Burgio, Gaëtan; Teboul, Lydia Trends in genetics : TIG. 33039248 2020 Dec;
Machine learning-based automated phenotyping of inflammatory nocifensive behavior in mice. Wotton, Janine M; Peterson, Emma; Anderson, Laura; Murray, Stephen A; Braun, Robert E; Chesler, Elissa J; White, Jacqueline K; Kumar, Vivek Molecular pain. 32955381 2020 Jan-Dec;
Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS Data. Sabik, Olivia L; Calabrese, Gina M; Taleghani, Eric; Ackert-Bicknell, Cheryl L; Farber, Charles R Cell reports 32937138 2020 09 15
Interactive and independent effects of early lipopolysaccharide and hyperoxia exposure on developing murine lungs. Shrestha, Amrit Kumar; Menon, Renuka T; El-Saie, Ahmed; Barrios, Roberto; Reynolds, Corey; Shivanna, Binoy American journal of physiology. Lung cellular and molecular physiology 32901520 2020 12 01
Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin. Ong, Seow Theng; Bajaj, Saumya; Tanner, Mark R; Chang, Shih Chieh; Krishnarjuna, Bankala; Ng, Xuan Rui; Morales, Rodrigo A V; Chen, Ming Wei; Luo, Dahai; Patel, Dharmeshkumar; Yasmin, Sabina; Ng, Jeremy Jun Heng; Zhuang, Zhong; Nguyen, Hai M; El Sahili, Abbas; Lescar, Julien; Patil, Rahul; Charman, Susan A; Robins, Edward G; Goggi, Julian L; Tan, Peng Wen; Sadasivam, Pragalath; Ramasamy, Boominathan; Hartimath, Siddana V; Dhawan, Vikas; Bednenko, Janna; Colussi, Paul; Wulff, Heike; Pennington, Michael W; Kuyucak, Serdar; Norton, Raymond S; Beeton, Christine; Chandy, K George ACS pharmacology & translational science. 32832873 2020 Aug 14;
Profound and redundant functions of arcuate neurons in obesity development. Zhu, Canjun; Jiang, Zhiying; Xu, Yuanzhong; Cai, Zhao-Lin; Jiang, Qingyan; Xu, Yong; Xue, Mingshan; Arenkiel, Benjamin R; Wu, Qi; Shu, Gang; Tong, Qingchun Nature metabolism. 32719538 2020 08;
ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility. Snyder, Elizabeth; Chukrallah, Lauren; Seltzer, Kelly; Goodwin, Leslie; Braun, Robert E Scientific reports. 32665638 2020 Jul 14;
Universal Southern blot protocol with cold or radioactive probes for the validation of alleles obtained by homologous recombination. Codner, Gemma F; Erbs, Valerie; Loeffler, Jorik; Chessum, Lauren; Caulder, Adam; Jullien, Nicolas; Wells, Sara; Birling, Marie-Christine; Teboul, Lydia Methods (San Diego, Calif.) 32599056 2021 07
Somatic Gain of KRAS Function in the Endothelium is Sufficient to Cause Vascular Malformations that Require MEK but not PI3K Signaling. Fish, Jason E; Flores-Suarez, Carlos Perfecto; Boudreau, Emilie; Herman, Alexander M; Gutierrez, Manuel Cantu; Gustafson, Dakota; DiStefano, Peter V; Cui, Meng; Chen, Zhiqi; Berman De Ruiz, Karen; Schexnayder, Taylor S; Ward, Christopher S; Radovanovic, Ivan; Wythe, Joshua D Circulation research. 32552404 2020 Jun 17;
The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities. Herbert, Eleanor; Stewart, Michelle; Hutchison, Marie; Flenniken, Ann M; Qu, Dawei; Nutter, Lauryl M J; McKerlie, Colin; Hobson, Liane; Kick, Brenda; Lyons, Bonnie; Wiegand, Jean-Paul; Doty, Rosalinda; Aguilar-Pimentel, Juan Antonio; Hrabe de Angelis, Martin; Dickinson, Mary; Seavitt, John; White, Jacqueline K; Scudamore, Cheryl L; Wells, Sara PloS one. 32542000 2020;
A global Slc7a7 knockout mouse model demonstrates characteristic phenotypes of human lysinuric protein intolerance. Stroup, Bridget M; Marom, Ronit; Li, Xiaohui; Hsu, Chih-Wei; Chang, Cheng-Yen; Truong, Luan D; Dawson, Brian; Grafe, Ingo; Chen, Yuqing; Jiang, Ming-Ming; Lanza, Denise; Green, Jennie Rose; Sun, Qin; Barrish, J P; Ani, Safa; Christiansen, Audrey E; Seavitt, John R; Dickinson, Mary E; Kheradmand, Farrah; Heaney, Jason D; Lee, Brendan; Burrage, Lindsay C Human molecular genetics 32504080 2020 Aug 03
Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities. Huang, Anna Yu-Szu; Woo, Junsung; Sardar, Debosmita; Lozzi, Brittney; Bosquez Huerta, Navish A; Lin, Chia-Ching John; Felice, Daniela; Jain, Antrix; Paulucci-Holthauzen, Adriana; Deneen, Benjamin Neuron. 32320644 2020 06 17;
Tie-2 Cre-Mediated Deficiency of Extracellular Signal-Regulated Kinase 2 Potentiates Experimental Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension in Neonatal Mice. Menon, Renuka T; Shrestha, Amrit Kumar; Barrios, Roberto; Reynolds, Corey; Shivanna, Binoy International journal of molecular sciences. 32244398 2020 Mar 31;
DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. Li, Ming-Wen; Lloyd, K C Kent Scientific reports. 32123279 2020 Mar 02;
Chromatin interaction analyses elucidate the roles of PRC2-bound silencers in mouse development. Ngan, Chew Yee; Wong, Chee Hong; Tjong, Harianto; Wang, Wenbo; Goldfeder, Rachel L; Choi, Cindy; He, Hao; Gong, Liang; Lin, Junyan; Urban, Barbara; Chow, Julianna; Li, Meihong; Lim, Joanne; Philip, Vivek; Murray, Stephen A; Wang, Haoyi; Wei, Chia-Lin Nature genetics. 32094912 2020 03;
Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice. Menon, Renuka T; Shrestha, Amrit Kumar; Reynolds, Corey L; Barrios, Roberto; Caron, Kathleen M; Shivanna, Binoy The American journal of pathology. 32093901 2020 03;
PATHBIO: an international training program for precision mouse phenotyping. Ruberte, Jesus; Schofield, Paul N; Brakebusch, Cord; Vogel, Peter; Herault, Yann; Gracia, Guillem; McKerlie, Colin; Hrab? de Angelis, Martin; Hagn, Michael; Sundberg, John P Mammalian genome : official journal of the International Mammalian Genome Society. 32088735 2020 02;
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes. Kollmus, Heike; Fuchs, Helmut; Lengger, Christoph; Haselimashhadi, Hamed; Bogue, Molly A; Östereicher, Manuela A; Horsch, Marion; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Beckers, Johannes; Calzada-Wack, Julia; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M; Klein-Rodewald, Tanja; Maier, Holger; Mayer-Kuckuk, Philipp; Miller, Gregor; Moreth, Kristin; Neff, Frauke; Rathkolb, Birgit; Rácz, Ildikó; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk; Graw, Jochen; Klopstock, Thomas; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Önder; Mason, Jeremy; Torres, Arturo; Mouse Phenome Database Team; Balling, Rudi; Mehaan, Terry; Gailus-Durner, Valerie; Schughart, Klaus; Hrab? de Angelis, Martin Mammalian genome : official journal of the International Mammalian Genome Society. 32060626 2020 02;
The Deep Genome Project. Lloyd, K C Kent; Adams, David J; Baynam, Gareth; Beaudet, Arthur L; Bosch, Fatima; Boycott, Kym M; Braun, Robert E; Caulfield, Mark; Cohn, Ronald; Dickinson, Mary E; Dobbie, Michael S; Flenniken, Ann M; Flicek, Paul; Galande, Sanjeev; Gao, Xiang; Grobler, Anne; Heaney, Jason D; Herault, Yann; de Angelis, Martin Hrab?; Lupski, James R; Lyonnet, Stanislas; Mallon, Ann-Marie; Mammano, Fabio; MacRae, Calum A; McInnes, Roderick; McKerlie, Colin; Meehan, Terrence F; Murray, Stephen A; Nutter, Lauryl M J; Obata, Yuichi; Parkinson, Helen; Pepper, Michael S; Sedlacek, Radislav; Seong, Je Kyung; Shiroishi, Toshihiko; Smedley, Damian; Tocchini-Valentini, Glauco; Valle, David; Wang, Chi-Kuang Leo; Wells, Sara; White, Jacqueline; Wurst, Wolfgang; Xu, Ying; Brown, Steve D M Genome biology. 32008577 2020 02 03;
Human and mouse essentiality screens as a resource for disease gene discovery. Cacheiro, Pilar; Muñoz-Fuentes, Violeta; Murray, Stephen A; Dickinson, Mary E; Bucan, Maja; Nutter, Lauryl M J; Peterson, Kevin A; Haselimashhadi, Hamed; Flenniken, Ann M; Morgan, Hugh; Westerberg, Henrik; Konopka, Tomasz; Hsu, Chih-Wei; Christiansen, Audrey; Lanza, Denise G; Beaudet, Arthur L; Heaney, Jason D; Fuchs, Helmut; Gailus-Durner, Valerie; Sorg, Tania; Prochazka, Jan; Novosadova, Vendula; Lelliott, Christopher J; Wardle-Jones, Hannah; Wells, Sara; Teboul, Lydia; Cater, Heather; Stewart, Michelle; Hough, Tertius; Wurst, Wolfgang; Sedlacek, Radislav; Adams, David J; Seavitt, John R; Tocchini-Valentini, Glauco; Mammano, Fabio; Braun, Robert E; McKerlie, Colin; Herault, Yann; de Angelis, Martin Hrab?; Mallon, Ann-Marie; Lloyd, K C Kent; Brown, Steve D M; Parkinson, Helen; Meehan, Terrence F; Smedley, Damian; Genomics England Research Consortium; International Mouse Phenotyping Consortium Nature communications. 32005800 2020 Jan 31;
PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis. Yu, Kwanha; Lin, Chia-Ching John; Hatcher, Asante; Lozzi, Brittney; Kong, Kathleen; Huang-Hobbs, Emmet; Cheng, Yi-Ting; Beechar, Vivek B; Zhu, Wenyi; Zhang, Yiqun; Chen, Fengju; Mills, Gordon B; Mohila, Carrie A; Creighton, Chad J; Noebels, Jeffrey L; Scott, Kenneth L; Deneen, Benjamin Nature. 31996845 2020 02;
Incremental data integration for tracking genotype-disease associations. Konopka, Tomasz; Smedley, Damian PLoS computational biology. 31986132 2020 01;
Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function. Findlay, Amy S; McKie, Lisa; Keighren, Margaret; Clementson-Mobbs, Sharon; Sanchez-Pulido, Luis; Wells, Sara; Cross, Sally H; Jackson, Ian J Scientific reports. 31949211 2020 Jan 16;
High-throughput discovery of genetic determinants of circadian misalignment. Zhang, Tao; Xie, Pancheng; Dong, Yingying; Liu, Zhiwei; Zhou, Fei; Pan, Dejing; Huang, Zhengyun; Zhai, Qiaocheng; Gu, Yue; Wu, Qingyu; Tanaka, Nobuhiko; Obata, Yuichi; Bradley, Allan; Lelliott, Christopher J; Sanger Institute Mouse Genetics Project; Nutter, Lauryl M J; McKerlie, Colin; Flenniken, Ann M; Champy, Marie-France; Sorg, Tania; Herault, Yann; Angelis, Martin Hrabe De; Durner, Valerie Gailus; Mallon, Ann-Marie; Brown, Steve D M; Meehan, Terry; Parkinson, Helen E; Smedley, Damian; Lloyd, K C Kent; Yan, Jun; Gao, Xiang; Seong, Je Kyung; Wang, Chi-Kuang Leo; Sedlacek, Radislav; Liu, Yi; Rozman, Jan; Yang, Ling; Xu, Ying PLoS genetics. 31929527 2020 01;
Metabolic dysregulation in the Atp7b-/- Wilson's disease mouse model. Wooton-Kee, Clavia Ruth; Robertson, Matthew; Zhou, Ying; Dong, Bingning; Sun, Zhen; Kim, Kang Ho; Liu, Hailan; Xu, Yong; Putluri, Nagireddy; Saha, Pradip; Coarfa, Cristian; Moore, David D; Nuotio-Antar, Alli M Proceedings of the National Academy of Sciences of the United States of America. 31924743 2020 Jan 28;
Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation. Stevens, Alexandra M; Xiang, Michael; Heppler, Lisa N; To?i?, Isidora; Jiang, Kevin; Munoz, Jaime O; Gaikwad, Amos S; Horton, Terzah M; Long, Xin; Narayanan, Padmini; Seashore, Elizabeth L; Terrell, Maci C; Rashid, Raushan; Krueger, Michael J; Mangubat-Medina, Alicia E; Ball, Zachary T; Sumazin, Pavel; Walker, Sarah R; Hamada, Yoshimasa; Oyadomari, Seiichi; Redell, Michele S; Frank, David A Blood advances. 31856268 2019 12 23;
High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation. Abeler-Dörner, Lucie; Laing, Adam G; Lorenc, Anna; Ushakov, Dmitry S; Clare, Simon; Speak, Anneliese O; Duque-Correa, Maria A; White, Jacqueline K; Ramirez-Solis, Ramiro; Saran, Namita; Bull, Katherine R; Morón, Belén; Iwasaki, Jua; Barton, Philippa R; Caetano, Susana; Hng, Keng I; Cambridge, Emma; Forman, Simon; Crockford, Tanya L; Griffiths, Mark; Kane, Leanne; Harcourt, Katherine; Brandt, Cordelia; Notley, George; Babalola, Kolawole O; Warren, Jonathan; Mason, Jeremy C; Meeniga, Amrutha; Karp, Natasha A; Melvin, David; Cawthorne, Eleanor; Weinrick, Brian; Rahim, Albina; Drissler, Sibyl; Meskas, Justin; Yue, Alice; Lux, Markus; Song-Zhao, George X; Chan, Anna; Ballesteros Reviriego, Carmen; Abeler, Johannes; Wilson, Heather; Przemska-Kosicka, Agnieszka; Edmans, Matthew; Strevens, Natasha; Pasztorek, Markus; Meehan, Terrence F; Powrie, Fiona; Brinkman, Ryan; Dougan, Gordon; Jacobs Jr, William; Lloyd, Clare M; Cornall, Richard J; Maloy, Kevin J; Grencis, Richard K; Griffiths, Gillian M; Adams, David J; Hayday, Adrian C Nature immunology. 31844327 2020 01;
NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells. Gupta, Shubhranshu S; Sharp, Robert; Hofferek, Colby; Kuai, Le; Dorn 2nd, Gerald W; Wang, Jin; Chen, Min Cell reports. 31722203 2019 11 12;
Improved Biomarker and Imaging Analysis for Characterizing Progressive Cardiac Fibrosis in a Mouse Model of Chronic Chagasic Cardiomyopathy. Hoffman, Kristyn A; Reynolds, Corey; Bottazzi, Maria Elena; Hotez, Peter; Jones, Kathryn Journal of the American Heart Association. 31718442 2019 11 19;
Effector gene expression underlying neuron subtype-specific traits in the Motor Ganglion of Ciona. Gibboney, Susanne; Orvis, Jameson; Kim, Kwantae; Johnson, Christopher J; Martinez-Feduchi, Paula; Lowe, Elijah K; Sharma, Sarthak; Stolfi, Alberto Developmental biology. 31639337 2020 Feb 01;
Long-range Pitx2c enhancer-promoter interactions prevent predisposition to atrial fibrillation. Zhang, Min; Hill, Matthew C; Kadow, Zachary A; Suh, Ji Ho; Tucker, Nathan R; Hall, Amelia W; Tran, Tien T; Swinton, Paul S; Leach, John P; Margulies, Kenneth B; Ellinor, Patrick T; Li, Na; Martin, James F Proceedings of the National Academy of Sciences of the United States of America. 31636200 2019 11 05;
Cytoglobin deficiency potentiates Crb1-mediated retinal degeneration in rd8 mice. Kwon, Young Sam; Tham, Addy; Lopez, Antonio Jacobo; Edwards, Sydney; Woods, Sean; Chen, Jiajia; Wong-Fortunato, Jenna; Quiroz Alonso, Alejandra; Javier, Seanne; Au, Ingrid; Clarke, Maria; Humpal, Devin; Lloyd, K C Kent; Thomasy, Sara; Murphy, Christopher; Glaser, Thomas M; Moshiri, Ala Developmental biology. 31634437 2020 Feb 15;
Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae. Jiang, Danye; Burger, Courtney A; Casasent, Anna K; Albrecht, Nicholas E; Li, Fenge; Samuel, Melanie A The Journal of comparative neurology. 31609468 2020 Apr 01;
Soft Windowing Application to Improve Analysis of High-throughput Phenotyping Data. Haselimashhadi, Hamed; Mason, Jeremy C; Munoz-Fuentes, Violeta; López-Gómez, Federico; Babalola, Kolawole; Acar, Elif F; Kumar, Vivek; White, Jacqui; Flenniken, Ann M; King, Ruairidh; Straiton, Ewan; Seavitt, John Richard; Gaspero, Angelina; Garza, Arturo; Christianson, Audrey E; Hsu, Chih-Wei; Reynolds, Corey L; Lanza, Denise G; Lorenzo, Isabel; Green, Jennie R; Gallegos, Juan J; Bohat, Ritu; Samaco, Rodney C; Veeraragavan, Surabi; Kim, Jong Kyoung; Miller, Gregor; Fuchs, Helmult; Garrett, Lillian; Becker, Lore; Kang, Yeon Kyung; Clary, David; Cho, Soo Young; Tamura, Masaru; Tanaka, Nobuhiko; Soo, Kyung Dong; Bezginov, Alexandr; About, Ghina Bou; Champy, Marie-France; Vasseur, Laurent; Leblanc, Sophie; Meziane, Hamid; Selloum, Mohammed; Reilly, Patrick T; Spielmann, Nadine; Maier, Holger; Gailus-Durner, Valerie; Sorg, Tania; Hiroshi, Masuya; Yuichi, Obata; Heaney, Jason D; Dickinson, Mary E; Wolfgang, Wurst; Tocchini-Valentini, Glauco P; Lloyd, Kevin C Kent; McKerlie, Colin; Seong, Je Kyung; Yann, Herault; de Angelis, Martin Hrabé; Brown, Steve D M; Smedley, Damian; Flicek, Paul; Mallon, Ann-Marie; Parkinson, Helen; Meehan, Terrence F Bioinformatics (Oxford, England). 31591642 2019 Oct 08;
Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis. Xiao, Yang; Hill, Matthew C; Li, Lele; Deshmukh, Vaibhav; Martin, Thomas J; Wang, Jun; Martin, James F Genes & development. 31558567 2019 11 01;
Genomic Mutation Identification in Mice Using Illumina Sequencing and Linux-Based Computational Methods. Williams, John A; Powell, George; Mallon, Ann-Marie; Simon, Michelle M Current protocols in mouse biology 31532925 2019 Sep
Endurance exercise leads to beneficial molecular and physiological effects in a mouse model of myotonic dystrophy type 1. Sharp, Lydia; Cox, Diana C; Cooper, Thomas A Muscle & nerve. 31509256 2019 12;
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation. Gurumurthy, Channabasavaiah B; O'Brien, Aidan R; Quadros, Rolen M; Adams Jr, John; Alcaide, Pilar; Ayabe, Shinya; Ballard, Johnathan; Batra, Surinder K; Beauchamp, Marie-Claude; Becker, Kathleen A; Bernas, Guillaume; Brough, David; Carrillo-Salinas, Francisco; Chan, Wesley; Chen, Hanying; Dawson, Ruby; DeMambro, Victoria; D'Hont, Jinke; Dibb, Katharine M; Eudy, James D; Gan, Lin; Gao, Jing; Gonzales, Amy; Guntur, Anyonya R; Guo, Huiping; Harms, Donald W; Harrington, Anne; Hentges, Kathryn E; Humphreys, Neil; Imai, Shiho; Ishii, Hideshi; Iwama, Mizuho; Jonasch, Eric; Karolak, Michelle; Keavney, Bernard; Khin, Nay-Chi; Konno, Masamitsu; Kotani, Yuko; Kunihiro, Yayoi; Lakshmanan, Imayavaramban; Larochelle, Catherine; Lawrence, Catherine B; Li, Lin; Lindner, Volkhard; Liu, Xian-De; Lopez-Castejon, Gloria; Loudon, Andrew; Lowe, Jenna; Jerome-Majewska, Loydie A; Matsusaka, Taiji; Miura, Hiromi; Miyasaka, Yoshiki; Morpurgo, Benjamin; Motyl, Katherine; Nabeshima, Yo-Ichi; Nakade, Koji; Nakashiba, Toshiaki; Nakashima, Kenichi; Obata, Yuichi; Ogiwara, Sanae; Ouellet, Mariette; Oxburgh, Leif; Piltz, Sandra; Pinz, Ilka; Ponnusamy, Moorthy P; Ray, David; Redder, Ronald J; Rosen, Clifford J; Ross, Nikki; Ruhe, Mark T; Ryzhova, Larisa; Salvador, Ane M; Alam, Sabrina Shameen; Sedlacek, Radislav; Sharma, Karan; Smith, Chad; Staes, Katrien; Starrs, Lora; Sugiyama, Fumihiro; Takahashi, Satoru; Tanaka, Tomohiro; Trafford, Andrew W; Uno, Yoshihiro; Vanhoutte, Leen; Vanrockeghem, Frederique; Willis, Brandon J; Wright, Christian S; Yamauchi, Yuko; Yi, Xin; Yoshimi, Kazuto; Zhang, Xuesong; Zhang, Yu; Ohtsuka, Masato; Das, Satyabrata; Garry, Daniel J; Hochepied, Tino; Thomas, Paul; Parker-Thornburg, Jan; Adamson, Antony D; Yoshiki, Atsushi; Schmouth, Jean-Francois; Golovko, Andrei; Thompson, William R; Lloyd, K C Kent; Wood, Joshua A; Cowan, Mitra; Mashimo, Tomoji; Mizuno, Seiya; Zhu, Hao; Kasparek, Petr; Liaw, Lucy; Miano, Joseph M; Burgio, Gaetan Genome biology. 31446895 2019 08 26;
Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. Moore, Bret A; Flenniken, Ann M; Clary, Dave; Moshiri, Ata S; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammad; McKerlie, Colin; International Mouse Phenotyping Consortium; Thomasy, Sara M; Lloyd, K C Kent; Murphy, Christopher J; Moshiri, Ala Scientific reports. 31371754 2019 Aug 01;
Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1. Cyranka, Malgorzata; Veprik, Anna; McKay, Eleanor J; van Loon, Nienke; Thijsse, Amber; Cotter, Luke; Hare, Nisha; Saibudeen, Affan; Lingam, Swathi; Pires, Elisabete; Larraufie, Pierre; Reimann, Frank; Gribble, Fiona; Stewart, Michelle; Bentley, Elizabeth; Lear, Pamela; McCullagh, James; Cantley, James; Cox, Roger D; de Wet, Heidi Obesity (Silver Spring, Md.). 31338999 2019 Aug;
S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation. Ren, Yi Athena; Monkkonen, Teresa; Lewis, Michael T; Bernard, Daniel J; Christian, Helen C; Jorgez, Carolina J; Moore, Joshua A; Landua, John D; Chin, Haelee M; Chen, Weiqin; Singh, Swarnima; Kim, Ik Sun; Zhang, Xiang Hf; Xia, Yan; Phillips, Kevin J; MacKay, Harry; Waterland, Robert A; Ljungberg, M Cecilia; Saha, Pradip K; Hartig, Sean M; Coll, Tatiana Fiordelisio; Richards, JoAnne S JCI insight. 31265437 2019 Jul 02;
Bmi1 Suppresses Adipogenesis in the Hematopoietic Stem Cell Niche. Hu, Tianyuan; Kitano, Ayumi; Luu, Victor; Dawson, Brian; Hoegenauer, Kevin A; Lee, Brendan H; Nakada, Daisuke Stem cell reports. 31257132 2019 Sep 10;
Luciferase Reporter Mice for In Vivo Monitoring and Ex Vivo Assessment of Hypothalamic Signaling of Socs3 Expression. Cordonier, Elizabeth L; Liu, Tiemin; Saito, Kenji; Chen, Siyu S; Xu, Yong; Fukuda, Makoto Journal of the Endocrine Society. 31214662 2019 Jul 01;
A cellular atlas of Pitx2-dependent cardiac development. Hill, Matthew C; Kadow, Zachary A; Li, Lele; Tran, Tien T; Wythe, Joshua D; Martin, James F Development (Cambridge, England). 31201182 2019 Jun 14;
High Resolution Imaging of Mouse Embryos and Neonates with X-Ray Micro-Computed Tomography. Hsu, Chih-Wei; Kalaga, Sowmya; Akoma, Uchechukwu; Rasmussen, Tara L; Christiansen, Audrey E; Dickinson, Mary E Current protocols in mouse biology. 31195428 2019 Jun;
Progressive myoclonic epilepsy-associated gene Kctd7 regulates retinal neurovascular patterning and function. Alevy, Jonathan; Burger, Courtney A; Albrecht, Nicholas E; Jiang, Danye; Samuel, Melanie A Neurochemistry international. 31175897 2019 Oct;
Non-monotonic dose-response effects of arsenic on glucose metabolism. Gong, Yingyun; Liu, Jidong; Xue, Yanfeng; Zhuang, Zhong; Qian, Sichong; Zhou, Wenjun; Li, Xin; Qian, Justin; Ding, Guolian; Sun, Zheng Toxicology and applied pharmacology. 31170414 2019 Aug 15;
New models for human disease from the International Mouse Phenotyping Consortium. Cacheiro, Pilar; Haendel, Melissa A; Smedley, Damian; International Mouse Phenotyping Consortium and the Monarch Initiative Mammalian genome : official journal of the International Mammalian Genome Society. 31127358 2019 Jun;
A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium. Barupal, Dinesh K; Zhang, Ying; Shen, Tong; Fan, Sili; Roberts, Bryan S; Fitzgerald, Patrick; Wancewicz, Benjamin; Valdiviez, Luis; Wohlgemuth, Gert; Byram, Gregory; Choy, Ying Yng; Haffner, Bennett; Showalter, Megan R; Vaniya, Arpana; Bloszies, Clayton S; Folz, Jacob S; Kind, Tobias; Flenniken, Ann M; McKerlie, Colin; Nutter, Lauryl M J; Lloyd, Kent C; Fiehn, Oliver Metabolites. 31121816 2019 May 22;
-Omics biomarker identification pipeline for translational medicine. Bravo-Merodio, Laura; Williams, John A; Gkoutos, Georgios V; Acharjee, Animesh Journal of translational medicine. 31088492 2019 05 14;
The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming. Rueda, Elda M; Hall, Benjamin M; Hill, Matthew C; Swinton, Paul G; Tong, Xuefei; Martin, James F; Poché, Ross A Cell reports. 31067451 2019 May 07;
TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells. Arhatte, Malika; Gunaratne, Gihan S; El Boustany, Charbel; Kuo, Ivana Y; Moro, Céline; Duprat, Fabrice; Plaisant, Magali; Duval, Hélène; Li, Dahui; Picard, Nicolas; Couvreux, Anais; Duranton, Christophe; Rubera, Isabelle; Pagnotta, Sophie; Lacas-Gervais, Sandra; Ehrlich, Barbara E; Marchant, Jonathan S; Savage, Aaron M; van Eeden, Fredericus J M; Wilkinson, Robert N; Demolombe, Sophie; Honoré, Eric; Patel, Amanda Nature communications. 31048699 2019 05 02;
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. Falcão, Ana Mendanha; Meijer, Mandy; Scaglione, Antonella; Rinwa, Puneet; Agirre, Eneritz; Liang, Jialiang; Larsen, Sara C; Heskol, Abeer; Frawley, Rebecca; Klingener, Michael; Varas-Godoy, Manuel; Raposo, Alexandre A S F; Ernfors, Patrik; Castro, Diogo S; Nielsen, Michael L; Casaccia, Patrizia; Castelo-Branco, Gonçalo Cell reports. 31018126 2019 Apr 23;
Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction. Li, Qiang; Youn, Ji Youn; Siu, Kin Lung; Murugesan, Priya; Zhang, Yixuan; Cai, Hua Redox biology. 30954686 2019 Jun;
Robust mouse tracking in complex environments using neural networks. Geuther, Brian Q; Deats, Sean P; Fox, Kai J; Murray, Steve A; Braun, Robert E; White, Jacqueline K; Chesler, Elissa J; Lutz, Cathleen M; Kumar, Vivek Communications biology. 30937403 2019;
Integrative transcriptomic analysis suggests new autoregulatory splicing events coupled with nonsense-mediated mRNA decay. Pervouchine, Dmitri; Popov, Yaroslav; Berry, Andy; Borsari, Beatrice; Frankish, Adam; Guigó, Roderic Nucleic acids research. 30916337 2019 Jun 04;
Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression. Kumagai, Motona; Guo, Xin; Wang, Ke-Yong; Izumi, Hiroto; Tsukamoto, Manabu; Nakashima, Tamiji; Tasaki, Takashi; Kurose, Nozomu; Uramoto, Hidetaka; Sasaguri, Yasuyuki; Kohno, Kimitoshi; Yamada, Sohsuke International journal of medical sciences. 30911276 2019;
Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts. Moore, Bret A; Leonard, Brian C; Sebbag, Lionel; Edwards, Sydney G; Cooper, Ann; Imai, Denise M; Straiton, Ewan; Santos, Luis; Reilly, Christopher; Griffey, Stephen M; Bower, Lynette; Clary, David; Mason, Jeremy; Roux, Michel J; Meziane, Hamid; Herault, Yann; International Mouse Phenotyping Consortium; McKerlie, Colin; Flenniken, Ann M; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammed; Hsu, Chih-Wei; Kalaga, Sowmya; Udensi, Uchechukwu; Asomugha, Chinwe; Bohat, Ritu; Gallegos, Juan J; Seavitt, John R; Heaney, Jason D; Beaudet, Arthur L; Dickinson, Mary E; Justice, Monica J; Philip, Vivek; Kumar, Vivek; Svenson, Karen L; Braun, Robert E; Wells, Sara; Cater, Heather; Stewart, Michelle; Clementson-Mobbs, Sharon; Joynson, Russell; Gao, Xiang; Suzuki, Tomohiro; Wakana, Shigeharu; Smedley, Damian; Seong, J K; Tocchini-Valentini, Glauco; Moore, Mark; Fletcher, Colin; Karp, Natasha; Ramirez-Solis, Ramiro; White, Jacqueline K; de Angelis, Martin Hrabe; Wurst, Wolfgang; Thomasy, Sara M; Flicek, Paul; Parkinson, Helen; Brown, Steve D M; Meehan, Terrence F; Nishina, Patsy M; Murray, Stephen A; Krebs, Mark P; Mallon, Ann-Marie; Kent Lloyd, K C; Murphy, Christopher J; Moshiri, Ala Communications biology. 30854487 2019;
Cytohesin-3 is required for full insulin receptor signaling and controls body weight via lipid excretion. Jux, Bettina; Gosejacob, Dominic; Tolksdorf, Felix; Mandel, Christa; Rieck, Michael; Namislo, Angrit; Pfeifer, Alexander; Kolanus, Waldemar Scientific reports. 30837656 2019 Mar 05;
Ocular phenotypic consequences of a single copy deletion of the Yap1 gene (Yap1+/-) in mice. Kim, Soohyun; Thomasy, Sara M; Raghunathan, Vijay Krishna; Teixeira, Leandro B C; Moshiri, Ala; FitzGerald, Paul; Murphy, Christopher J Molecular vision. 30820148 2019;
Tead1 is required for perinatal cardiomyocyte proliferation. Liu, Ruya; Jagannathan, Rajaganapathi; Li, Feng; Lee, Jeongkyung; Balasubramanyam, Nikhil; Kim, Byung S; Yang, Ping; Yechoor, Vijay K; Moulik, Mousumi PloS one. 30811446 2019;
YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo. Monroe, Tanner O; Hill, Matthew C; Morikawa, Yuka; Leach, John P; Heallen, Todd; Cao, Shuyi; Krijger, Peter H L; de Laat, Wouter; Wehrens, Xander H T; Rodney, George G; Martin, James F Developmental cell. 30773489 2019 Mar 25;
Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. Burrage, Lindsay C; Reynolds, John J; Baratang, Nissan Vida; Phillips, Jennifer B; Wegner, Jeremy; McFarquhar, Ashley; Higgs, Martin R; Christiansen, Audrey E; Lanza, Denise G; Seavitt, John R; Jain, Mahim; Li, Xiaohui; Parry, David A; Raman, Vandana; Chitayat, David; Chinn, Ivan K; Bertuch, Alison A; Karaviti, Lefkothea; Schlesinger, Alan E; Earl, Dawn; Bamshad, Michael; Savarirayan, Ravi; Doddapaneni, Harsha; Muzny, Donna; Jhangiani, Shalini N; Eng, Christine M; Gibbs, Richard A; Bi, Weimin; Emrick, Lisa; Rosenfeld, Jill A; Postlethwait, John; Westerfield, Monte; Dickinson, Mary E; Beaudet, Arthur L; Ranza, Emmanuelle; Huber, Celine; Cormier-Daire, Valérie; Shen, Wei; Mao, Rong; Heaney, Jason D; Orange, Jordan S; University of Washington Center for Mendelian Genomics; Undiagnosed Diseases Network; Bertola, Débora; Yamamoto, Guilherme L; Baratela, Wagner A R; Butler, Merlin G; Ali, Asim; Adeli, Mehdi; Cohn, Daniel H; Krakow, Deborah; Jackson, Andrew P; Lees, Melissa; Offiah, Amaka C; Carlston, Colleen M; Carey, John C; Stewart, Grant S; Bacino, Carlos A; Campeau, Philippe M; Lee, Brendan American journal of human genetics. 30773277 2019 Mar 07;
Transcriptional analysis of Foxp3+ Tregs and functions of two identified molecules during resolution of ALI. Mock, Jason R; Dial, Catherine F; Tune, Miriya K; Norton, Dustin L; Martin, Jessica R; Gomez, John C; Hagan, Robert S; Dang, Hong; Doerschuk, Claire M JCI insight. 30753170 2019 Mar 21;
Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche. Salazar, Valerie S; Capelo, Luciane P; Cantù, Claudio; Zimmerli, Dario; Gosalia, Nehal; Pregizer, Steven; Cox, Karen; Ohte, Satoshi; Feigenson, Marina; Gamer, Laura; Nyman, Jeffry S; Carey, David J; Economides, Aris; Basler, Konrad; Rosen, Vicki eLife. 30735122 2019 Feb 08;
Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities. Stewart, Michelle; Lau, Petrina; Banks, Gareth; Bains, Rasneer Sonia; Castroflorio, Enrico; Oliver, Peter L; Dixon, Christine L; Kruer, Michael C; Kullmann, Dimitri M; Acevedo-Arozena, Abraham; Wells, Sara E; Corrochano, Silvia; Nolan, Patrick M Disease models & mechanisms. 30692144 2019 Feb 22;
Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Zhou, Wenjun; He, Yanlin; Rehman, Atteeq U; Kong, Yan; Hong, Sungguan; Ding, Guolian; Yalamanchili, Hari Krishna; Wan, Ying-Wooi; Paul, Basil; Wang, Chuhan; Gong, Yingyun; Zhou, Wenxian; Liu, Hao; Dean, John; Scalais, Emmanuel; O'Driscoll, Mary; Morton, Jenny E V; DDD study; Hou, Xinguo; Wu, Qi; Tong, Qingchun; Liu, Zhandong; Liu, Pengfei; Xu, Yong; Sun, Zheng Nature neuroscience. 30664766 2019 02;
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis. Goodwin, Leslie O; Splinter, Erik; Davis, Tiffany L; Urban, Rachel; He, Hao; Braun, Robert E; Chesler, Elissa J; Kumar, Vivek; van Min, Max; Ndukum, Juliet; Philip, Vivek M; Reinholdt, Laura G; Svenson, Karen; White, Jacqueline K; Sasner, Michael; Lutz, Cathleen; Murray, Stephen A Genome research. 30659012 2019 Mar;
Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma. Monsivais, Diana; Peng, Jia; Kang, Yibin; Matzuk, Martin M Proceedings of the National Academy of Sciences of the United States of America. 30655341 2019 Feb 26;
Using CRISPR/Cas9 engineering to generate a mouse with a conditional knockout allele for the promyelocytic leukemia zinc finger transcription factor. Hai, Lan; Szwarc, Maria M; Lanza, Denise G; Heaney, Jason D; Lydon, John P Genesis (New York, N.Y. : 2000). 30628160 2019 Mar;
Generating mouse models for biomedical research: technological advances. Gurumurthy, Channabasavaiah B; Lloyd, Kevin C Kent Disease models & mechanisms. 30626588 2019 01 08;
Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults. Lo Re, Oriana; Mazza, Tommaso; Vinciguerra, Manlio Frontiers in genetics. 30619475 2018;
KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis. Tanner, Mark R; Pennington, Michael W; Chauhan, Satendra S; Laragione, Teresina; Gulko, Pércio S; Beeton, Christine Arthritis research & therapy. 30612588 2019 Jan 07;
Identification of genes required for eye development by high-throughput screening of mouse knockouts. Moore, Bret A; Leonard, Brian C; Sebbag, Lionel; Edwards, Sydney G; Cooper, Ann; Imai, Denise M; Straiton, Ewan; Santos, Luis; Reilly, Christopher; Griffey, Stephen M; Bower, Lynette; Clary, David; Mason, Jeremy; Roux, Michel J; Meziane, Hamid; Herault, Yann; International Mouse Phenotyping Consortium; McKerlie, Colin; Flenniken, Ann M; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammed; Hsu, Chih-Wei; Kalaga, Sowmya; Udensi, Uchechukwu; Asomugha, Chinwe; Bohat, Ritu; Gallegos, Juan J; Seavitt, John R; Heaney, Jason D; Beaudet, Arthur L; Dickinson, Mary E; Justice, Monica J; Philip, Vivek; Kumar, Vivek; Svenson, Karen L; Braun, Robert E; Wells, Sara; Cater, Heather; Stewart, Michelle; Clementson-Mobbs, Sharon; Joynson, Russell; Gao, Xiang; Suzuki, Tomohiro; Wakana, Shigeharu; Smedley, Damian; Seong, J K; Tocchini-Valentini, Glauco; Moore, Mark; Fletcher, Colin; Karp, Natasha; Ramirez-Solis, Ramiro; White, Jacqueline K; de Angelis, Martin Hrabe; Wurst, Wolfgang; Thomasy, Sara M; Flicek, Paul; Parkinson, Helen; Brown, Steve D M; Meehan, Terrence F; Nishina, Patsy M; Murray, Stephen A; Krebs, Mark P; Mallon, Ann-Marie; Lloyd, K C Kent; Murphy, Christopher J; Moshiri, Ala Communications biology. 30588515 2018;
Gi/o protein-coupled receptors in dopamine neurons inhibit the sodium leak channel NALCN. Philippart, Fabian; Khaliq, Zayd M eLife. 30556810 2018 12 17;
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice. Xu, Wenqiong; Zhou, Hongyi; Xuan, Hongzhuan; Saha, Pradip; Wang, Gongxian; Chen, Weiqin Molecular and cellular endocrinology. 30521848 2019 Feb 15;
Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model. Kim, Hyeongseok; Kim, Yeong Gi; Choi, Wonsuk; Moon, Joon Ho; Hwang, Inseon; Kim, Kyuho; Yadav, Vijay K; Karsenty, Gerard; Jeong, Ji-Seon; Kim, Hail Scientific reports. 30518775 2018 Dec 05;
Utility of HbA1c assessment in people with diabetes awaiting liver transplantation. Bhattacharjee, D; Vracar, S; Round, R A; Nightingale, P G; Williams, J A; Gkoutos, G V; Stratton, I M; Parker, R; Luzio, S D; Webber, J; Manley, S E; Roberts, G A; Ghosh, S Diabetic medicine : a journal of the British Diabetic Association. 30474191 2018 Nov 26;
IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections. Shepardson, Kelly M; Larson, Kyle; Johns, Laura L; Stanek, Kayla; Cho, Hanbyul; Wellham, Julia; Henderson, Haley; Rynda-Apple, Agnieszka Frontiers in immunology. 30473701 2018;
WDFY4 is required for cross-presentation in response to viral and tumor antigens. Theisen, Derek J; Davidson 4th, Jesse T; Briseño, Carlos G; Gargaro, Marco; Lauron, Elvin J; Wang, Qiuling; Desai, Pritesh; Durai, Vivek; Bagadia, Prachi; Brickner, Joshua R; Beatty, Wandy L; Virgin, Herbert W; Gillanders, William E; Mosammaparast, Nima; Diamond, Michael S; Sibley, L David; Yokoyama, Wayne; Schreiber, Robert D; Murphy, Theresa L; Murphy, Kenneth M Science (New York, N.Y.). 30409884 2018 11 09;
The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex. Panda, Swarupa; Gekara, Nelson O Nature communications. 30405132 2018 11 07;
FAM92A Underlies Nonsyndromic Postaxial Polydactyly in Humans and an Abnormal Limb and Digit Skeletal Phenotype in Mice. Schrauwen, Isabelle; Giese, Arnaud Pj; Aziz, Abdul; Lafont, David Tino; Chakchouk, Imen; Santos-Cortez, Regie Lyn P; Lee, Kwanghyuk; Acharya, Anushree; Khan, Falak Sher; Ullah, Asmat; Nickerson, Deborah A; Bamshad, Michael J; Ali, Ghazanfar; Riazuddin, Saima; Ansar, Muhammad; Ahmad, Wasim; Ahmed, Zubair M; Leal, Suzanne M Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30395363 2019 Feb;
Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism. Tassi, Elena; Garman, Khalid A; Schmidt, Marcel O; Ma, Xiaoting; Kabbara, Khaled W; Uren, Aykut; Tomita, York; Goetz, Regina; Mohammadi, Moosa; Wilcox, Christopher S; Riegel, Anna T; Carlstrom, Mattias; Wellstein, Anton Scientific reports. 30374109 2018 Oct 29;
Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia. Sundberg, John P; Shen, Tong; Fiehn, Oliver; Rice, Robert H; Silva, Kathleen A; Kennedy, Victoria E; Gott, Nicholas E; Dionne, Louise A; Bechtold, Lesley S; Murray, Stephen A; Kuiper, Raoul; Pratt, C Herbert PloS one. 30372477 2018;
CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias. Pang, Paul D; Alsina, Katherina M; Cao, Shuyi; Koushik, Amrita B; Wehrens, Xander H T; Cooper, Thomas A Journal of the American Heart Association. 30371314 2018 Oct 02;
Haploinsufficiency of autism spectrum disorder candidate gene NUAK1 impairs cortical development and behavior in mice. Courchet, Virginie; Roberts, Amanda J; Meyer-Dilhet, Géraldine; Del Carmine, Peggy; Lewis Jr, Tommy L; Polleux, Franck; Courchet, Julien Nature communications. 30327473 2018 10 16;
Comparison of cryosurvival and spermatogenesis efficiency of cryopreserved neonatal mouse testicular tissue between three vitrification protocols and controlled-rate freezing. Yildiz, Cengiz; Mullen, Brendan; Jarvi, Keith; McKerlie, Colin; Lo, Kirk C Cryobiology. 30195700 2018 10;
Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Szwarc, Maria M; Kommagani, Ramakrishna; Putluri, Vasanta; Dubrulle, Julien; Stossi, Fabio; Mancini, Michael A; Coarfa, Cristian; Lanz, Rainer B; Putluri, Nagireddy; DeMayo, Francesco J; Lydon, John P; O'Malley, Bert W Scientific reports. 30177747 2018 Sep 03;
Rapid and Integrative Discovery of Retina Regulatory Molecules. Albrecht, Nicholas E; Alevy, Jonathan; Jiang, Danye; Burger, Courtney A; Liu, Brian I; Li, Fenge; Wang, Julia; Kim, Seon-Young; Hsu, Chih-Wei; Kalaga, Sowmya; Udensi, Uchechukwu; Asomugha, Chinwe; Bohat, Ritu; Gaspero, Angelina; Justice, Monica J; Westenskow, Peter D; Yamamoto, Shinya; Seavitt, John R; Beaudet, Arthur L; Dickinson, Mary E; Samuel, Melanie A Cell reports. 30157441 2018 Aug 28;
Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes. Lee, Sang H; Shin, Seung Min; Zhong, Peng; Kim, Hyun-Taek; Kim, Dong-Il; Kim, June Myoung; Do Heo, Won; Kim, Dae-Won; Yeo, Chang-Yeol; Kim, Cheol-Hee; Liu, Qing-Song Nature communications. 30143647 2018 08 24;
Ndr kinases regulate retinal interneuron proliferation and homeostasis. Léger, Hélène; Santana, Evelyn; Leu, N Adrian; Smith, Eliot T; Beltran, William A; Aguirre, Gustavo D; Luca, Francis C Scientific reports. 30135513 2018 Aug 22;
The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation. Muñoz-Fuentes, Violeta; Cacheiro, Pilar; Meehan, Terrence F; Aguilar-Pimentel, Juan Antonio; Brown, Steve D M; Flenniken, Ann M; Flicek, Paul; Galli, Antonella; Mashhadi, Hamed Haseli; Hrab? de Angelis, Martin; Kim, Jong Kyoung; Lloyd, K C Kent; McKerlie, Colin; Morgan, Hugh; Murray, Stephen A; Nutter, Lauryl M J; Reilly, Patrick T; Seavitt, John R; Seong, Je Kyung; Simon, Michelle; Wardle-Jones, Hannah; Mallon, Ann-Marie; Smedley, Damian; Parkinson, Helen E; IMPC consortium Conservation genetics (Print). 30100824 2018;
Characterization of Tissue Plasminogen Activator Expression and Trafficking in the Adult Murine Brain. Stevenson, Tamara K; Lawrence, Daniel A eNeuro. 30090852 2018 Jul-Aug;
Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy. Napoli, Eleonora; Song, Gyu; Panoutsopoulos, Alexios; Riyadh, M Asrafuzzaman; Kaushik, Gaurav; Halmai, Julian; Levenson, Richard; Zarbalis, Konstantinos S; Giulivi, Cecilia Scientific reports. 30054502 2018 Jul 27;
Engineering Point Mutant and Epitope-Tagged Alleles in Mice Using Cas9 RNA-Guided Nuclease. Gertsenstein, Marina; Nutter, Lauryl M J Current protocols in mouse biology. 30040228 2018 Mar;
TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. Cheung, Sin Ying; Henrot, Matthias; Al-Saad, Mohammad; Baumann, Matthias; Muller, Heiko; Unger, Anke; Rubaiy, Hussein N; Mathar, Ilka; Dinkel, Klaus; Nussbaumer, Peter; Klebl, Bert; Freichel, Marc; Rode, Baptiste; Trainor, Sebastian; Clapcote, Steven J; Christmann, Mathias; Waldmann, Herbert; Abbas, Syed Khawar; Beech, David J; Vasudev, Naveen S Oncotarget. 30038709 2018 Jul 03;
Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis. Paulo, Esther; Wu, Dongmei; Wang, Yangmeng; Zhang, Yun; Wu, Yixuan; Swaney, Danielle L; Soucheray, Margaret; Jimenez-Morales, David; Chawla, Ajay; Krogan, Nevan J; Wang, Biao Scientific reports. 30030465 2018 Jul 20;
Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages. Recio, Carlota; Lucy, Daniel; Purvis, Gareth S D; Iveson, Poppy; Zeboudj, Lynda; Iqbal, Asif J; Lin, Daniel; O'Callaghan, Chris; Davison, Lucy; Griesbach, Esther; Russell, Angela J; Wynne, Graham M; Dib, Lea; Monaco, Claudia; Greaves, David R Frontiers in immunology. 29973940 2018;
Rbfox-Splicing Factors Maintain Skeletal Muscle Mass by Regulating Calpain3 and Proteostasis. Singh, Ravi K; Kolonin, Arseniy M; Fiorotto, Marta L; Cooper, Thomas A Cell reports. 29972780 2018 Jul 03;
C.B-17 SCID mice develop epicardial calcinosis with unaltered cardiac function. Raghunathan, Suchi; Reynolds, Corey L; Schwartz, Robert J; Stewart, M David; McConnell, Bradley K Fundamental & clinical pharmacology. 29959870 2018 Jun 30;
Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants. Codner, Gemma F; Mianné, Joffrey; Caulder, Adam; Loeffler, Jorik; Fell, Rachel; King, Ruairidh; Allan, Alasdair J; Mackenzie, Matthew; Pike, Fran J; McCabe, Christopher V; Christou, Skevoulla; Joynson, Sam; Hutchison, Marie; Stewart, Michelle E; Kumar, Saumya; Simon, Michelle M; Agius, Loranne; Anstee, Quentin M; Volynski, Kirill E; Kullmann, Dimitri M; Wells, Sara; Teboul, Lydia BMC biology. 29925374 2018 Jun 21;
Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles. Lanza, Denise G; Gaspero, Angelina; Lorenzo, Isabel; Liao, Lan; Zheng, Ping; Wang, Ying; Deng, Yu; Cheng, Chonghui; Zhang, Chuansheng; Seavitt, John R; DeMayo, Francesco J; Xu, Jianming; Dickinson, Mary E; Beaudet, Arthur L; Heaney, Jason D BMC biology. 29925370 2018 Jun 21;
Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain. Carbajosa, Guillermo; Malki, Karim; Lawless, Nathan; Wang, Hong; Ryder, John W; Wozniak, Eva; Wood, Kristie; Mein, Charles A; Dobson, Richard J B; Collier, David A; O'Neill, Michael J; Hodges, Angela K; Newhouse, Stephen J Neurobiology of aging. 29906661 2018 09;
FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex. Künzel, Ulrike; Grieve, Adam Graham; Meng, Yao; Sieber, Boris; Cowley, Sally A; Freeman, Matthew eLife. 29897336 2018 06 13;
Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity. Zhang, Ming-Dong; Su, Jie; Adori, Csaba; Cinquina, Valentina; Malenczyk, Katarzyna; Girach, Fatima; Peng, Changgeng; Ernfors, Patrik; Löw, Peter; Borgius, Lotta; Kiehn, Ole; Watanabe, Masahiko; Uhlén, Mathias; Mitsios, Nicholas; Mulder, Jan; Harkany, Tibor; Hökfelt, Tomas The Journal of clinical investigation. 29893745 2018 08 31;
Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment. Sukumaran, Sujita; Watanabe, Norihiro; Bajgain, Pradip; Raja, Kanchana; Mohammed, Somala; Fisher, William E; Brenner, Malcolm K; Leen, Ann M; Vera, Juan F Cancer discovery. 29880586 2018 Aug;
High-resolution ?CT of a mouse embryo using a compact laser-driven X-ray betatron source. Cole, Jason M; Symes, Daniel R; Lopes, Nelson C; Wood, Jonathan C; Poder, Kristjan; Alatabi, Saleh; Botchway, Stanley W; Foster, Peta S; Gratton, Sarah; Johnson, Sara; Kamperidis, Christos; Kononenko, Olena; De Lazzari, Michael; Palmer, Charlotte A J; Rusby, Dean; Sanderson, Jeremy; Sandholzer, Michael; Sarri, Gianluca; Szoke-Kovacs, Zsombor; Teboul, Lydia; Thompson, James M; Warwick, Jonathan R; Westerberg, Henrik; Hill, Mark A; Norris, Dominic P; Mangles, Stuart P D; Najmudin, Zulfikar Proceedings of the National Academy of Sciences of the United States of America. 29871946 2018 06 19;
A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice. Moore, Bret A; Roux, Michel J; Sebbag, Lionel; Cooper, Ann; Edwards, Sydney G; Leonard, Brian C; Imai, Denise M; Griffey, Stephen; Bower, Lynette; Clary, Dave; Lloyd, K C Kent; Hérault, Yann; Thomasy, Sara M; Murphy, Christopher J; Moshiri, Ala Investigative ophthalmology & visual science. 29847629 2018 May 01;
Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation. Yao, Chunxia; Veleva, Tina; Scott Jr, Larry; Cao, Shuyi; Li, Luge; Chen, Gong; Jeyabal, Prince; Pan, Xiaolu; Alsina, Katherina M; Abu-Taha Dr, Issam; Ghezelbash, Shokoufeh; Reynolds, Corey L; Shen, Ying H; LeMaire, Scott A; Schmitz, Wilhelm; Müller, Frank U; El-Armouche, Ali; Tony Eissa, N; Beeton, Christine; Nattel, Stanley; Wehrens, Xander H T; Dobrev, Dobromir; Li, Na Circulation. 29802206 2018 11 13;
Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1. Morriss, Ginny R; Rajapakshe, Kimal; Huang, Shixia; Coarfa, Cristian; Cooper, Thomas A Human molecular genetics. 29771332 ;
Efficient mouse genome engineering by CRISPR-EZ technology. Modzelewski, Andrew J; Chen, Sean; Willis, Brandon J; Lloyd, K C Kent; Wood, Joshua A; He, Lin Nature protocols. 29748649 2018 06;
SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program. Ratnadiwakara, Madara; Archer, Stuart K; Dent, Craig I; Ruiz De Los Mozos, Igor; Beilharz, Traude H; Knaupp, Anja S; Nefzger, Christian M; Polo, Jose M; Anko, Minna-Liisa eLife. 29741478 2018 05 09;
Adar3 Is Involved in Learning and Memory in Mice. Mladenova, Dessislava; Barry, Guy; Konen, Lyndsey M; Pineda, Sandy S; Guennewig, Boris; Avesson, Lotta; Zinn, Raphael; Schonrock, Nicole; Bitar, Maina; Jonkhout, Nicky; Crumlish, Lauren; Kaczorowski, Dominik C; Gong, Andrew; Pinese, Mark; Franco, Gloria R; Walkley, Carl R; Vissel, Bryce; Mattick, John S Frontiers in neuroscience. 29719497 2018;
Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome. De Pace, Raffaella; Skirzewski, Miguel; Damme, Markus; Mattera, Rafael; Mercurio, Jeffrey; Foster, Arianne M; Cuitino, Loreto; Jarnik, Michal; Hoffmann, Victoria; Morris, H Douglas; Han, Tae-Un; Mancini, Grazia M S; Buonanno, Andrés; Bonifacino, Juan S PLoS genetics. 29698489 2018 04;
Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development. Xiao, Yang; Hill, Matthew C; Zhang, Min; Martin, Thomas J; Morikawa, Yuka; Wang, Suya; Moise, Alexander R; Wythe, Joshua D; Martin, James F Developmental cell. 29689192 2018 04 23;
Pathogenic Effects of IFIT2 and Interferon-? during Fatal Systemic Candida albicans Infection. Stawowczyk, Marcin; Naseem, Shamoon; Montoya, Valeria; Baker, Darren P; Konopka, James; Reich, Nancy C mBio. 29666281 2018 04 17;
IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer. You, Ran; DeMayo, Francesco J; Liu, Jian; Cho, Sung-Nam; Burt, Bryan M; Creighton, Chad J; Casal, Roberto F; Lazarus, Donald R; Lu, Wen; Tung, Hui-Ying; Yuan, Xiaoyi; Hill-McAlester, Andrea; Kim, Myunghoo; Perusich, Sarah; Cornwell, Loraine; Rosen, Daniel; Song, Li-Zhen; Paust, Silke; Diehl, Gretchen; Corry, David; Kheradmand, Farrah Cancer immunology research. 29653981 2018 06;
Renal proteomic analysis of RGC-32 knockout mice reveals the potential mechanism of RGC-32 in regulating cell cycle. Hu, Yu-Jie; Zhou, Qian; Li, Zhu-Yin; Feng, Dan; Sun, Lei; Shen, Yun-Lin; Huang, Wen-Yan American journal of translational research. 29636874 2018;
High-throughput mouse phenomics for characterizing mammalian gene function. Brown, Steve D M; Holmes, Chris C; Mallon, Ann-Marie; Meehan, Terrence F; Smedley, Damian; Wells, Sara Nature reviews. Genetics. 29626206 2018 Jun;
The role of FREM2 and FRAS1 in the development of congenital diaphragmatic hernia. Jordan, Valerie K; Beck, Tyler F; Hernandez-Garcia, Andres; Kundert, Peter N; Kim, Bum-Jun; Jhangiani, Shalini N; Gambin, Tomasz; Starkovich, Molly; Punetha, Jaya; Paine, Ingrid S; Posey, Jennifer E; Li, Alexander H; Muzny, Donna; Hsu, Chih-Wei; Lashua, Amber J; Sun, Xin; Fernandes, Caraciolo J; Dickinson, Mary E; Lally, Kevin P; Gibbs, Richard A; Boerwinkle, Eric; Lupski, James R; Scott, Daryl A Human molecular genetics. 29618029 2018 06 15;
Response to ''Unexpected mutations after CRISPR-Cas9 editing in vivo''. Nutter, Lauryl M J; Heaney, Jason D; Lloyd, K C Kent; Murray, Stephen A; Seavitt, John R; Skarnes, William C; Teboul, Lydia; Brown, Steve D M; Moore, Mark Nature methods. 29600991 2018 Apr;
Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice. Wang, Ke-Yong; Yamada, Sohsuke; Izumi, Hiroto; Tsukamoto, Manabu; Nakashima, Tamiji; Tasaki, Takashi; Guo, Xin; Uramoto, Hidetaka; Sasaguri, Yasuyuki; Kohno, Kimitoshi PloS one. 29596490 2018;
Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2). Zhong, Li; Wang, Zongqi; Wang, Daxin; Wang, Zhe; Martens, Yuka A; Wu, Linbei; Xu, Ying; Wang, Kai; Li, Jianguo; Huang, Ruizhi; Can, Dan; Xu, Huaxi; Bu, Guojun; Chen, Xiao-Fen Molecular neurodegeneration. 29587871 2018 03 27;
Unexplored therapeutic opportunities in the human genome. Oprea, Tudor I; Bologa, Cristian G; Brunak, Søren; Campbell, Allen; Gan, Gregory N; Gaulton, Anna; Gomez, Shawn M; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L; Karlson, Anneli; Leach, Andrew R; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Steven L; McManus, Michael T; Meehan, Terrence F; von Mering, Christian; Muthas, Daniel; Nguyen, Dac-Trung; Overington, John P; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L; Schürer, Stephan C; Simeonov, Anton; Sklar, Larry A; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Du?ica; Waller, Anna; Westergaard, David; Yang, Jeremy J; Zahoránszky-Köhalmi, Gergely Nature reviews. Drug discovery. 29567993 2018 May;
Dynamic Imaging of Mouse Embryos and Cardiodynamics in Static Culture. Lopez 3rd, Andrew L; Larina, Irina V Methods in molecular biology (Clifton, N.J.). 29564760 2018;
Loss of the Intellectual Disability and Autism Gene Cc2d1a and Its Homolog Cc2d1b Differentially Affect Spatial Memory, Anxiety, and Hyperactivity. Zamarbide, Marta; Oaks, Adam W; Pond, Heather L; Adelman, Julia S; Manzini, M Chiara Frontiers in genetics. 29552027 2018;
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining. Li, Conglei; Irrazabal, Thergiory; So, Clare C; Berru, Maribel; Du, Likun; Lam, Evelyn; Ling, Alexanda K; Gommerman, Jennifer L; Pan-Hammarström, Qiang; Martin, Alberto Nature communications. 29520062 2018 03 08;
Contribution of metabolic disease to bone fragility in MAGP1-deficient mice. Turecamo, S E; Walji, T A; Broekelmann, T J; Williams, J W; Ivanov, S; Wee, N K; Procknow, J D; McManus, M R; Randolph, G J; Scheller, E L; Mecham, R P; Craft, C S Matrix biology : journal of the International Society for Matrix Biology. 29519758 2018 04;
Loss of cone function without degeneration in a novel Gnat2 knock-out mouse. Ronning, Kaitryn E; Allina, Gabriel Peinado; Miller, Eric B; Zawadzki, Robert J; Pugh Jr, Edward N; Herrmann, Rolf; Burns, Marie E Experimental eye research. 29518352 2018 06;
TRPV6, TRPM6 and TRPM7 Do Not Contribute to Hair-Cell Mechanotransduction. Morgan, Clive P; Zhao, Hongyu; LeMasurier, Meredith; Xiong, Wei; Pan, Bifeng; Kazmierczak, Piotr; Avenarius, Matthew R; Bateschell, Michael; Larisch, Ruby; Ricci, Anthony J; Müller, Ulrich; Barr-Gillespie, Peter G Frontiers in cellular neuroscience. 29515374 2018;
SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function. Matt, Lucas; Kirk, Lyndsey M; Chenaux, George; Speca, David J; Puhger, Kyle R; Pride, Michael C; Qneibi, Mohammad; Haham, Tomer; Plambeck, Kristopher E; Stern-Bach, Yael; Silverman, Jill L; Crawley, Jacqueline N; Hell, Johannes W; Díaz, Elva Cell reports. 29490264 2018 Feb 27;
Unexplored therapeutic opportunities in the human genome. Oprea, Tudor I; Bologa, Cristian G; Brunak, Søren; Campbell, Allen; Gan, Gregory N; Gaulton, Anna; Gomez, Shawn M; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L; Karlson, Anneli; Leach, Andrew R; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Stephen L; McManus, Michael T; Meehan, Terrence F; von Mering, Christian; Muthas, Daniel; Nguyen, Dac-Trung; Overington, John P; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L; Schürer, Stephan C; Simeonov, Anton; Sklar, Larry A; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Du?ica; Waller, Anna; Westergaard, David; Yang, Jeremy J; Zahoránszky-Köhalmi, Gergely Nature reviews. Drug discovery. 29472638 2018 May;
Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic Angiogenesis. Fan, Yanbo; Lu, Haocheng; Liang, Wenying; Garcia-Barrio, Minerva T; Guo, Yanhong; Zhang, Ji; Zhu, Tianqing; Hao, Yibai; Zhang, Jifeng; Chen, Y Eugene Circulation research. 29467198 2018 Mar 30;
Correction to: Characterization of bone morphology in CCN5/WISP2 knockout mice. Jiang, Jie; Zhao, Gexin; Lyons, Karen M Journal of cell communication and signaling. 29455304 2018 Mar;
Targeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid Arthritis. Tanner, Mark R; Pennington, Michael W; Chamberlain, Brayden H; Huq, Redwan; Gehrmann, Elizabeth J; Laragione, Teresina; Gulko, Pércio S; Beeton, Christine The Journal of pharmacology and experimental therapeutics. 29453198 2018 May;
A Seminiferous Tubule Squash Technique for the Cytological Analysis of Spermatogenesis Using the Mouse Model. Wellard, Stephen R; Hopkins, Jessica; Jordan, Philip W Journal of visualized experiments : JoVE 29443055 2018 02 06
Family with sequence similarity 13, member A modulates adipocyte insulin signaling and preserves systemic metabolic homeostasis. Wardhana, Donytra Arby; Ikeda, Koji; Barinda, Agian Jeffilano; Nugroho, Dhite Bayu; Qurania, Kikid Rucira; Yagi, Keiko; Miyata, Keishi; Oike, Yuichi; Hirata, Ken-Ichi; Emoto, Noriaki Proceedings of the National Academy of Sciences of the United States of America. 29386390 2018 02 13;
Phenotyping acute and chronic atopic dermatitis-like lesions in Stat6VT mice identifies a role for IL-33 in disease pathogenesis. DaSilva-Arnold, Sonia C; Thyagarajan, Anita; Seymour, Leroy J; Yi, Qiaofang; Bradish, Joshua R; Al-Hassani, Mohammed; Zhou, Hongming; Perdue, Nikolajs J; Nemeth, Val; Krbanjevic, Aleksandar; Serezani, Ana P M; Olson, Matthew R; Spandau, Dan F; Travers, Jeffrey B; Kaplan, Mark H; Turner, Matthew J Archives of dermatological research. 29368135 2018 Apr;
Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershäuser, Monja; Brommage, Robert; Meehan, Terrence F; Mason, Jeremy; Haselimashhadi, Hamed; IMPC Consortium; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J; White, Jacqueline K; Sorg, Tania; Champy, Marie-France; Bower, Lynette R; Reynolds, Corey L; Flenniken, Ann M; Murray, Stephen A; Nutter, Lauryl M J; Svenson, Karen L; West, David; Tocchini-Valentini, Glauco P; Beaudet, Arthur L; Bosch, Fatima; Braun, Robert B; Dobbie, Michael S; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A; Kent Lloyd, K C; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D; Tschöp, Matthias H; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas; Hrabe de Angelis, Martin Nature communications. 29348434 2018 Jan 18;
Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis. Regensburger, Martin; Prots, Iryna; Reimer, Dorothea; Brachs, Sebastian; Loskarn, Sandra; Lie, Dieter Chichung; Mielenz, Dirk; Winner, Beate Stem cell reports. 29337116 2018 02 13;
A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice. Abdelhamed, Zakia; Vuong, Shawn M; Hill, Lauren; Shula, Crystal; Timms, Andrew; Beier, David; Campbell, Kenneth; Mangano, Francesco T; Stottmann, Rolf W; Goto, June Development (Cambridge, England). 29317443 2018 01 09;
Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice. Kidana, Kiwami; Tatebe, Takuya; Ito, Kaori; Hara, Norikazu; Kakita, Akiyoshi; Saito, Takashi; Takatori, Sho; Ouchi, Yasuyoshi; Ikeuchi, Takeshi; Makino, Mitsuhiro; Saido, Takaomi C; Akishita, Masahiro; Iwatsubo, Takeshi; Hori, Yukiko; Tomita, Taisuke EMBO molecular medicine. 29311134 2018 03;
Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population. Huang, Lei; Wu, Kuo-Ho; Zhang, Liyong; Wang, Qinchuan; Tang, Shuangbo; Wu, Qiuping; Jiang, Pei-Hsiu; Lin, Jim Jung-Ching; Guo, Jian; Wang, Lin; Loh, Shih-Hurng; Cheng, Jianding Journal of the American Heart Association. 29306897 2018 01 06;
Robust model-based analysis of single-particle tracking experiments with Spot-On. Hansen, Anders S; Woringer, Maxime; Grimm, Jonathan B; Lavis, Luke D; Tjian, Robert; Darzacq, Xavier eLife. 29300163 2018 Jan 04;
Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. Pol, Arjan; Renkema, G Herma; Tangerman, Albert; Winkel, Edwin G; Engelke, Udo F; de Brouwer, Arjan P M; Lloyd, Kent C; Araiza, Renee S; van den Heuvel, Lambert; Omran, Heymut; Olbrich, Heike; Oude Elberink, Marijn; Gilissen, Christian; Rodenburg, Richard J; Sass, Jörn Oliver; Schwab, K Otfried; Schäfer, Hendrik; Venselaar, Hanka; Sequeira, J Silvia; Op den Camp, Huub J M; Wevers, Ron A Nature genetics. 29255262 2018 Jan;
Long-term pulmonary and cardiovascular morbidities of neonatal hyperoxia exposure in mice. Menon, Renuka T; Shrestha, Amrit Kumar; Reynolds, Corey L; Barrios, Roberto; Shivanna, Binoy The international journal of biochemistry & cell biology. 29223466 2018 Jan;
Corrigendum: High-throughput discovery of novel developmental phenotypes. Dickinson, Mary E; Flenniken, Ann M; Ji, Xiao; Teboul, Lydia; Wong, Michael D; White, Jacqueline K; Meehan, Terrence F; Weninger, Wolfgang J; Westerberg, Henrik; Adissu, Hibret; Baker, Candice N; Bower, Lynette; Brown, James M; Caddle, L Brianna; Chiani, Francesco; Clary, Dave; Cleak, James; Daly, Mark J; Denegre, James M; Doe, Brendan; Dolan, Mary E; Edie Helmut Fuchs, Sarah M; Gailus-Durner, Valerie; Galli, Antonella; Gambadoro, Alessia; Gallegos, Juan; Guo, Shiying; Horner, Neil R; Hsu, Chih-Wei; Johnson, Sara J; Kalaga, Sowmya; Keith, Lance C; Lanoue, Louise; Lawson, Thomas N; Lek, Monkol; Mark, Manuel; Marschall, Susan; Mason, Jeremy; McElwee, Melissa L; Nutter, Susan Newbigging Lauryl M J; Peterson, Kevin A; Ramirez-Solis, Ramiro; Rowland, Douglas J; Ryder, Edward; Samocha, Kaitlin E; Seavitt, John R; Selloum, Mohammed; Szoke-Kovacs, Zsombor; Tamura, Masaru; Trainor, Amanda G; Tudose, Ilinca; Wakana, Shigeharu; Warren, Jonathan; Wendling, Olivia; West, David B; Wong, Leeyean; Yoshiki, Atsushi; International Mouse Phenotyping Consortium; Wurst, Wolfgang; MacArthur, Daniel G; Tocchini-Valentini, Glauco P; Gao, Xiang; Flicek, Paul; Bradley, Allan; Skarnes, William C; Justice, Monica J; Parkinson, Helen E; Moore, Mark; Wells, Sara; Braun, Robert E; Svenson, Karen L; de Angelis, Martin Hrabe; Herault, Yann; Mohun, Tim; Mallon, Ann-Marie; Henkelman, R Mark; Brown, Steve D M; Adams, David J; Lloyd, K C Kent; McKerlie, Colin; Beaudet, Arthur L; Murray, Maja Bu?an Stephen A Nature. 29144450 2017 Nov 16;
Asprosin is a centrally acting orexigenic hormone. Duerrschmid, Clemens; He, Yanlin; Wang, Chunmei; Li, Chia; Bournat, Juan C; Romere, Chase; Saha, Pradip K; Lee, Mark E; Phillips, Kevin J; Jain, Mahim; Jia, Peilin; Zhao, Zhongming; Farias, Monica; Wu, Qi; Milewicz, Dianna M; Sutton, V Reid; Moore, David D; Butte, Nancy F; Krashes, Michael J; Xu, Yong; Chopra, Atul R Nature medicine. 29106398 2017 Dec;
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Bowl, Michael R; Simon, Michelle M; Ingham, Neil J; Greenaway, Simon; Santos, Luis; Cater, Heather; Taylor, Sarah; Mason, Jeremy; Kurbatova, Natalja; Pearson, Selina; Bower, Lynette R; Clary, Dave A; Meziane, Hamid; Reilly, Patrick; Minowa, Osamu; Kelsey, Lois; International Mouse Phenotyping Consortium; Tocchini-Valentini, Glauco P; Gao, Xiang; Bradley, Allan; Skarnes, William C; Moore, Mark; Beaudet, Arthur L; Justice, Monica J; Seavitt, John; Dickinson, Mary E; Wurst, Wolfgang; de Angelis, Martin Hrabe; Herault, Yann; Wakana, Shigeharu; Nutter, Lauryl M J; Flenniken, Ann M; McKerlie, Colin; Murray, Stephen A; Svenson, Karen L; Braun, Robert E; West, David B; Lloyd, K C Kent; Adams, David J; White, Jacqui; Karp, Natasha; Flicek, Paul; Smedley, Damian; Meehan, Terrence F; Parkinson, Helen E; Teboul, Lydia M; Wells, Sara; Steel, Karen P; Mallon, Ann-Marie; Brown, Steve D M Nature communications. 29026089 2017 Oct 12;
Revealing hidden complexities of genomic rearrangements generated with Cas9. Boroviak, Katharina; Fu, Beiyuan; Yang, Fengtang; Doe, Brendan; Bradley, Allan Scientific reports. 28993641 2017 Oct 09;
Hippo pathway deficiency reverses systolic heart failure after infarction. Leach, John P; Heallen, Todd; Zhang, Min; Rahmani, Mahdis; Morikawa, Yuka; Hill, Matthew C; Segura, Ana; Willerson, James T; Martin, James F Nature. 28976966 2017 10 12;
A scoring system for the evaluation of the mutated Crb1/rd8-derived retinal lesions in C57BL/6N mice. Concas, Danilo; Cater, Heather; Wells, Sara F1000Research. 28928942 2017;
Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy. Liu, Ruya; Lee, Jeongkyung; Kim, Byung S; Wang, Qiongling; Buxton, Samuel K; Balasubramanyam, Nikhil; Kim, Jean J; Dong, Jianrong; Zhang, Aijun; Li, Shumin; Gupte, Anisha A; Hamilton, Dale J; Martin, James F; Rodney, George G; Coarfa, Cristian; Wehrens, Xander Ht; Yechoor, Vijay K; Moulik, Mousumi JCI insight. 28878117 2017 Sep 07;
Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Freyer, Laina; Hsu, Chih-Wei; Nowotschin, Sonja; Pauli, Andrea; Ishida, Junji; Kuba, Keiji; Fukamizu, Akiyoshi; Schier, Alexander F; Hoodless, Pamela A; Dickinson, Mary E; Hadjantonakis, Anna-Katerina Cell reports. 28854362 2017 Aug 29;
Phenotyping first-generation genome editing mutants: a new standard? Teboul, Lydia; Murray, Stephen A; Nolan, Patrick M Mammalian genome : official journal of the International Mammalian Genome Society. 28756587 2017 Aug;
A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans. Brophy, Patrick D; Rasmussen, Maria; Parida, Mrutyunjaya; Bonde, Greg; Darbro, Benjamin W; Hong, Xiaojing; Clarke, Jason C; Peterson, Kevin A; Denegre, James; Schneider, Michael; Sussman, Caroline R; Sunde, Lone; Lildballe, Dorte L; Hertz, Jens Michael; Cornell, Robert A; Murray, Stephen A; Manak, J Robert Genetics. 28739660 2017 09;
Cardiac reprogramming factor Gata4 reduces postinfarct cardiac fibrosis through direct repression of the profibrotic mediator snail. Mathison, Megumi; Singh, Vivek P; Sanagasetti, Deepthi; Yang, Lina; Pinnamaneni, Jaya Pratap; Yang, Jianchang; Rosengart, Todd K The Journal of thoracic and cardiovascular surgery. 28711329 2017 Nov;
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. Sundberg, John P; Dadras, Soheil S; Silva, Kathleen A; Kennedy, Victoria E; Garland, Gaven; Murray, Stephen A; Sundberg, Beth A; Schofield, Paul N; Pratt, C Herbert PloS one. 28700664 2017;
Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation. Fidler, Trevor P; Middleton, Elizabeth; Rowley, Jesse W; Boudreau, Luc H; Campbell, Robert A; Souvenir, Rhonda; Funari, Trevor; Tessandier, Nicolas; Boilard, Eric; Weyrich, Andrew S; Abel, E Dale Arteriosclerosis, thrombosis, and vascular biology. 28663252 2017 Jun 29;
Prevalence of sexual dimorphism in mammalian phenotypic traits. Karp, Natasha A; Mason, Jeremy; Beaudet, Arthur L; Benjamini, Yoav; Bower, Lynette; Braun, Robert E; Brown, Steve D M; Chesler, Elissa J; Dickinson, Mary E; Flenniken, Ann M; Fuchs, Helmut; Angelis, Martin Hrabe de; Gao, Xiang; Guo, Shiying; Greenaway, Simon; Heller, Ruth; Herault, Yann; Justice, Monica J; Kurbatova, Natalja; Lelliott, Christopher J; Lloyd, K C Kent; Mallon, Ann-Marie; Mank, Judith E; Masuya, Hiroshi; McKerlie, Colin; Meehan, Terrence F; Mott, Richard F; Murray, Stephen A; Parkinson, Helen; Ramirez-Solis, Ramiro; Santos, Luis; Seavitt, John R; Smedley, Damian; Sorg, Tania; Speak, Anneliese O; Steel, Karen P; Svenson, Karen L; International Mouse Phenotyping Consortium; Wakana, Shigeharu; West, David; Wells, Sara; Westerberg, Henrik; Yaacoby, Shay; White, Jacqueline K Nature communications. 28650954 2017 Jun 26;
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium. Meehan, Terrence F; Conte, Nathalie; West, David B; Jacobsen, Julius O; Mason, Jeremy; Warren, Jonathan; Chen, Chao-Kung; Tudose, Ilinca; Relac, Mike; Matthews, Peter; Karp, Natasha; Santos, Luis; Fiegel, Tanja; Ring, Natalie; Westerberg, Henrik; Greenaway, Simon; Sneddon, Duncan; Morgan, Hugh; Codner, Gemma F; Stewart, Michelle E; Brown, James; Horner, Neil; International Mouse Phenotyping Consortium; Haendel, Melissa; Washington, Nicole; Mungall, Christopher J; Reynolds, Corey L; Gallegos, Juan; Gailus-Durner, Valerie; Sorg, Tania; Pavlovic, Guillaume; Bower, Lynette R; Moore, Mark; Morse, Iva; Gao, Xiang; Tocchini-Valentini, Glauco P; Obata, Yuichi; Cho, Soo Young; Seong, Je Kyung; Seavitt, John; Beaudet, Arthur L; Dickinson, Mary E; Herault, Yann; Wurst, Wolfgang; de Angelis, Martin Hrabe; Lloyd, K C Kent; Flenniken, Ann M; Nutter, Lauryl M J; Newbigging, Susan; McKerlie, Colin; Justice, Monica J; Murray, Stephen A; Svenson, Karen L; Braun, Robert E; White, Jacqueline K; Bradley, Allan; Flicek, Paul; Wells, Sara; Skarnes, William C; Adams, David J; Parkinson, Helen; Mallon, Ann-Marie; Brown, Steve D M; Smedley, Damian Nature genetics. 28650483 2017 Jun 26;
Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation. Morikawa, Yuka; Heallen, Todd; Leach, John; Xiao, Yang; Martin, James F Nature. 28581498 2017 07 13;
The complex genetics of hypoplastic left heart syndrome. Liu, Xiaoqin; Yagi, Hisato; Saeed, Shazina; Bais, Abha S; Gabriel, George C; Chen, Zhaohan; Peterson, Kevin A; Li, You; Schwartz, Molly C; Reynolds, William T; Saydmohammed, Manush; Gibbs, Brian; Wu, Yijen; Devine, William; Chatterjee, Bishwanath; Klena, Nikolai T; Kostka, Dennis; de Mesy Bentley, Karen L; Ganapathiraju, Madhavi K; Dexheimer, Phillip; Leatherbury, Linda; Khalifa, Omar; Bhagat, Anchit; Zahid, Maliha; Pu, William; Watkins, Simon; Grossfeld, Paul; Murray, Stephen A; Porter Jr, George A; Tsang, Michael; Martin, Lisa J; Benson, D Woodrow; Aronow, Bruce J; Lo, Cecilia W Nature genetics. 28530678 ;
Speckle variance optical coherence tomography of blood flow in the beating mouse embryonic heart. Grishina, Olga A; Wang, Shang; Larina, Irina V Journal of biophotonics. 28417585 2017 May;
Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analog. Tanner, Mark R; Tajhya, Rajeev B; Huq, Redwan; Gehrmann, Elizabeth J; Rodarte, Kathia E; Atik, Mustafa A; Norton, Raymond S; Pennington, Michael W; Beeton, Christine Clinical immunology (Orlando, Fla.). 28389388 2017 Jul;
Analysing the outcome of CRISPR-aided genome editing in embryos: Screening, genotyping and quality control. Mianné, Joffrey; Codner, Gemma F; Caulder, Adam; Fell, Rachel; Hutchison, Marie; King, Ruairidh; Stewart, Michelle E; Wells, Sara; Teboul, Lydia Methods (San Diego, Calif.). 28363792 2017 05 15;
Biallelic Variants in OTUD6B Cause an Intellectual Disability Syndrome Associated with Seizures and Dysmorphic Features. Santiago-Sim, Teresa; Burrage, Lindsay C; Ebstein, Frédéric; Tokita, Mari J; Miller, Marcus; Bi, Weimin; Braxton, Alicia A; Rosenfeld, Jill A; Shahrour, Maher; Lehmann, Andrea; Cogné, Benjamin; Küry, Sébastien; Besnard, Thomas; Isidor, Bertrand; Bézieau, Stéphane; Hazart, Isabelle; Nagakura, Honey; Immken, LaDonna L; Littlejohn, Rebecca O; Roeder, Elizabeth; EuroEPINOMICS RES Consortium Autosomal Recessive working group, S. Hande Caglayan; Kara, Bulent; Hardies, Katia; Weckhuysen, Sarah; May, Patrick; Lemke, Johannes R; Elpeleg, Orly; Abu-Libdeh, Bassam; James, Kiely N; Silhavy, Jennifer L; Issa, Mahmoud Y; Zaki, Maha S; Gleeson, Joseph G; Seavitt, John R; Dickinson, Mary E; Ljungberg, M Cecilia; Wells, Sara; Johnson, Sara J; Teboul, Lydia; Eng, Christine M; Yang, Yaping; Kloetzel, Peter-Michael; Heaney, Jason D; Walkiewicz, Magdalena A American journal of human genetics. 28343629 2017 Apr 06;
A chemical chaperone improves muscle function in mice with a RyR1 mutation. Lee, Chang Seok; Hanna, Amy D; Wang, Hui; Dagnino-Acosta, Adan; Joshi, Aditya D; Knoblauch, Mark; Xia, Yan; Georgiou, Dimitra K; Xu, Jianjun; Long, Cheng; Amano, Hisayuki; Reynolds, Corey; Dong, Keke; Martin, John C; Lagor, William R; Rodney, George G; Sahin, Ergun; Sewry, Caroline; Hamilton, Susan L Nature communications. 28337975 2017 Mar 24;
Arap1 Deficiency Causes Photoreceptor Degeneration in Mice. Moshiri, Ala; Humpal, Devin; Leonard, Brian C; Imai, Denise M; Tham, Addy; Bower, Lynette; Clary, Dave; Glaser, Thomas M; Lloyd, K C Kent; Murphy, Christopher J Investigative ophthalmology & visual science. 28324111 2017 Mar 01;
CRISPRtools: a flexible computational platform for performing CRISPR/Cas9 experiments in the mouse. Peterson, Kevin A; Beane, Glen L; Goodwin, Leslie O; Kutny, Peter M; Reinholdt, Laura G; Murray, Stephen A Mammalian genome : official journal of the International Mammalian Genome Society. 28280930 2017 Mar 09;
Multimodal embryonic imaging using optical coherence tomography, selective plane illumination microscopy, and optical projection tomography. Singh, M; Wu, C; Mayerich, D; Dickinson, M E; Larina, I V; Larin, K V Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 28269143 2016 08;
A bioluminescence reporter mouse that monitors expression of constitutively active ?-catenin. Szwarc, Maria M; Kommagani, Ramakrishna; Peavey, Mary C; Hai, Lan; Lonard, David M; Lydon, John P PloS one. 28253313 2017;
Applanation optical coherence elastography: noncontact measurement of intraocular pressure, corneal biomechanical properties, and corneal geometry with a single instrument. Singh, Manmohan; Han, Zhaolong; Nair, Achuth; Schill, Alexander; Twa, Michael D; Larin, Kirill V Journal of biomedical optics. 28241272 2017 02 01;
Of mice and CRISPR: The post-CRISPR future of the mouse as a model system for the human condition. Liu, Edison T; Bolcun-Filas, Ewelina; Grass, David S; Lutz, Cathleen; Murray, Steve; Shultz, Lenny; Rosenthal, Nadia EMBO reports. 28119373 2017 Feb;
Dynamic imaging and quantitative analysis of cranial neural tube closure in the mouse embryo using optical coherence tomography. Wang, Shang; Garcia, Monica D; Lopez 3rd, Andrew L; Overbeek, Paul A; Larin, Kirill V; Larina, Irina V Biomedical optics express. 28101427 2017 Jan 01;
Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells. Choi, Yong Jin; Lin, Chao-Po; Risso, Davide; Chen, Sean; Kim, Thomas Aquinas; Tan, Meng How; Li, Jin Billy; Wu, Yalei; Chen, Caifu; Xuan, Zhenyu; Macfarlan, Todd; Peng, Weiqun; Lloyd, K C Kent; Kim, Sang Yong; Speed, Terence P; He, Lin Science (New York, N.Y.). 28082412 2017 02 10;
APOBEC1 complementation factor (A1CF) is dispensable for C-to-U RNA editing in vivo. Snyder, Elizabeth M; McCarty, Christopher; Mehalow, Adrienne; Svenson, Karen L; Murray, Stephen A; Korstanje, Ron; Braun, Robert E RNA (New York, N.Y.). 28069890 2017 04;
Optical coherence elastography for evaluating customized riboflavin/UV-A corneal collagen crosslinking. Singh, Manmohan; Li, Jiasong; Vantipalli, Srilatha; Han, Zhaolong; Larin, Kirill V; Twa, Michael D Journal of biomedical optics. 28055060 2017 09 01;
Three-Dimensional High-Frequency Ultrasonography for Early Detection and Characterization of Embryo Implantation Site Development in the Mouse. Peavey, Mary C; Reynolds, Corey L; Szwarc, Maria M; Gibbons, William E; Valdes, Cecilia T; DeMayo, Francesco J; Lydon, John P PloS one. 28046063 2017;
SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice. Hinton Jr, Antentor Othrell; Yang, Yongjie; Quick, Ann P; Xu, Pingwen; Reddy, Chitra L; Yan, Xiaofeng; Reynolds, Corey L; Tong, Qingchun; Zhu, Liangru; Xu, Jianming; Wehrens, Xander H T; Xu, Yong; Reddy, Anilkumar K PloS one. 28006821 2016;
The impact of intraocular pressure on elastic wave velocity estimates in the crystalline lens. Park, Suhyun; Yoon, Heechul; Larin, Kirill V; Emelianov, Stanislav Y; Aglyamov, Salavat R Physics in medicine and biology. 27997379 2016 Dec 20;
Improving the Identification of Phenotypic Abnormalities and Sexual Dimorphism in Mice When Studying Rare Event Categorical Characteristics. Karp, Natasha A; Heller, Ruth; Yaacoby, Shay; White, Jacqueline K; Benjamini, Yoav Genetics. 27932544 2017 Feb;
Efficient gene targeting in mouse zygotes mediated by CRISPR/Cas9-protein. Jung, Chris J; Zhang, Junli; Trenchard, Elizabeth; Lloyd, Kent C; West, David B; Rosen, Barry; de Jong, Pieter J Transgenic research. 27905063 2017 Apr;
SVEP1 plays a crucial role in epidermal differentiation. Samuelov, Liat; Li, Qiaoli; Bochner, Ron; Najor, Nicole A; Albrecht, Lauren; Malchin, Natalia; Goldsmith, Tomer; Grafi-Cohen, Meital; Vodo, Dan; Fainberg, Gilad; Meilik, Benjamin; Goldberg, Ilan; Warshauer, Emily; Rogers, Tova; Edie, Sarah; Ishida-Yamamoto, Akemi; Burzenski, Lisa; Erez, Noam; Murray, Steve A; Irvine, Alan D; Shultz, Lenny; Green, Kathleen J; Uitto, Jouni; Sprecher, Eli; Sarig, Ofer Experimental dermatology. 27892606 2017 May;
Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release. Reynolds, Julia O; Quick, Ann P; Wang, Qiongling; Beavers, David L; Philippen, Leonne E; Showell, Jordan; Barreto-Torres, Giselle; Thuerauf, Donna J; Doroudgar, Shirin; Glembotski, Christopher C; Wehrens, Xander H T International journal of cardiology. 27760414 2016 Dec 15;
Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1. Giudice, Jimena; Xia, Zheng; Li, Wei; Cooper, Thomas A Scientific reports. 27759042 2016 10 19;
A bioimage informatics platform for high-throughput embryo phenotyping. Brown, James M; Horner, Neil R; Lawson, Thomas N; Fiegel, Tanja; Greenaway, Simon; Morgan, Hugh; Ring, Natalie; Santos, Luis; Sneddon, Duncan; Teboul, Lydia; Vibert, Jennifer; Yaikhom, Gagarine; Westerberg, Henrik; Mallon, Ann-Marie Briefings in bioinformatics. 27742664 2018 01 01;
SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity. Quick, Ann P; Wang, Qiongling; Philippen, Leonne E; Barreto-Torres, Giselle; Chiang, David Y; Beavers, David; Wang, Guoliang; Khalid, Maha; Reynolds, Julia O; Campbell, Hannah M; Showell, Jordan; McCauley, Mark D; Scholten, Arjen; Wehrens, Xander H T Circulation research. 27729468 2017 Jan 06;
Three-dimensional microCT imaging of mouse development from early post-implantation to early postnatal stages. Hsu, Chih-Wei; Wong, Leeyean; Rasmussen, Tara L; Kalaga, Sowmya; McElwee, Melissa L; Keith, Lance C; Bohat, Ritu; Seavitt, John R; Beaudet, Arthur L; Dickinson, Mary E Developmental biology. 27671873 2016 Nov 15;
Quantifying tissue viscoelasticity using optical coherence elastography and the Rayleigh wave model. Han, Zhaolong; Singh, Manmohan; Aglyamov, Salavat R; Liu, Chih-Hao; Nair, Achuth; Raghunathan, Raksha; Wu, Chen; Li, Jiasong; Larin, Kirill V Journal of biomedical optics. 27653931 2016 09 01;
High-throughput discovery of novel developmental phenotypes. Dickinson, Mary E; Flenniken, Ann M; Ji, Xiao; Teboul, Lydia; Wong, Michael D; White, Jacqueline K; Meehan, Terrence F; Weninger, Wolfgang J; Westerberg, Henrik; Adissu, Hibret; Baker, Candice N; Bower, Lynette; Brown, James M; Caddle, L Brianna; Chiani, Francesco; Clary, Dave; Cleak, James; Daly, Mark J; Denegre, James M; Doe, Brendan; Dolan, Mary E; Edie, Sarah M; Fuchs, Helmut; Gailus-Durner, Valerie; Galli, Antonella; Gambadoro, Alessia; Gallegos, Juan; Guo, Shiying; Horner, Neil R; Hsu, Chih-Wei; Johnson, Sara J; Kalaga, Sowmya; Keith, Lance C; Lanoue, Louise; Lawson, Thomas N; Lek, Monkol; Mark, Manuel; Marschall, Susan; Mason, Jeremy; McElwee, Melissa L; Newbigging, Susan; Nutter, Lauryl M J; Peterson, Kevin A; Ramirez-Solis, Ramiro; Rowland, Douglas J; Ryder, Edward; Samocha, Kaitlin E; Seavitt, John R; Selloum, Mohammed; Szoke-Kovacs, Zsombor; Tamura, Masaru; Trainor, Amanda G; Tudose, Ilinca; Wakana, Shigeharu; Warren, Jonathan; Wendling, Olivia; West, David B; Wong, Leeyean; Yoshiki, Atsushi; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center; MacArthur, Daniel G; Tocchini-Valentini, Glauco P; Gao, Xiang; Flicek, Paul; Bradley, Allan; Skarnes, William C; Justice, Monica J; Parkinson, Helen E; Moore, Mark; Wells, Sara; Braun, Robert E; Svenson, Karen L; de Angelis, Martin Hrabe; Herault, Yann; Mohun, Tim; Mallon, Ann-Marie; Henkelman, R Mark; Brown, Steve D M; Adams, David J; Lloyd, K C Kent; McKerlie, Colin; Beaudet, Arthur L; Bu?an, Maja; Murray, Stephen A Nature. 27626380 2016 Sep 14;
Lorentz force optical coherence elastography. Wu, Chen; Singh, Manmohan; Han, Zhaolong; Raghunathan, Raksha; Liu, Chih-Hao; Li, Jiasong; Schill, Alexander; Larin, Kirill V Journal of biomedical optics. 27622242 2016 09 01;
A Whole-Genome Analysis Framework for Effective Identification of Pathogenic Regulatory Variants in Mendelian Disease. Smedley, Damian; Schubach, Max; Jacobsen, Julius O B; Köhler, Sebastian; Zemojtel, Tomasz; Spielmann, Malte; Jäger, Marten; Hochheiser, Harry; Washington, Nicole L; McMurry, Julie A; Haendel, Melissa A; Mungall, Christopher J; Lewis, Suzanna E; Groza, Tudor; Valentini, Giorgio; Robinson, Peter N American journal of human genetics. 27569544 2016 Sep 01;
Noncontact Elastic Wave Imaging Optical Coherence Elastography for Evaluating Changes in Corneal Elasticity Due to Crosslinking. Singh, Manmohan; Li, Jiasong; Vantipalli, Srilatha; Wang, Shang; Han, Zhaolong; Nair, Achuth; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill V IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. 27547022 2016 May-Jun;
Mesp1 Marked Cardiac Progenitor Cells Repair Infarcted Mouse Hearts. Liu, Yu; Chen, Li; Diaz, Andrea Diaz; Benham, Ashley; Xu, Xueping; Wijaya, Cori S; Fa'ak, Faisal; Luo, Weijia; Soibam, Benjamin; Azares, Alon; Yu, Wei; Lyu, Qiongying; Stewart, M David; Gunaratne, Preethi; Cooney, Austin; McConnell, Bradley K; Schwartz, Robert J Scientific reports. 27538477 2016 08 19;
Investigating Elastic Anisotropy of the Porcine Cornea as a Function of Intraocular Pressure With Optical Coherence Elastography. Singh, Manmohan; Li, Jiasong; Han, Zhaolong; Wu, Chen; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill V Journal of refractive surgery (Thorofare, N.J. : 1995). 27505317 2016 Aug 01;
Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction. Codner, Gemma F; Lindner, Loic; Caulder, Adam; Wattenhofer-Donzé, Marie; Radage, Adam; Mertz, Annelyse; Eisenmann, Benjamin; Mianné, Joffrey; Evans, Edward P; Beechey, Colin V; Fray, Martin D; Birling, Marie-Christine; Hérault, Yann; Pavlovic, Guillaume; Teboul, Lydia BMC cell biology. 27496052 2016 Aug 05;
C13orf31 (FAMIN) is a central regulator of immunometabolic function. Cader, M Zaeem; Boroviak, Katharina; Zhang, Qifeng; Assadi, Ghazaleh; Kempster, Sarah L; Sewell, Gavin W; Saveljeva, Svetlana; Ashcroft, Jonathan W; Clare, Simon; Mukhopadhyay, Subhankar; Brown, Karen P; Tschurtschenthaler, Markus; Raine, Tim; Doe, Brendan; Chilvers, Edwin R; Griffin, Jules L; Kaneider, Nicole C; Floto, R Andres; D'Amato, Mauro; Bradley, Allan; Wakelam, Michael J O; Dougan, Gordon; Kaser, Arthur Nature immunology. 27478939 2016 09;
Phenotypic assessment of pulmonary hypertension using high-resolution echocardiography is feasible in neonatal mice with experimental bronchopulmonary dysplasia and pulmonary hypertension: a step toward preventing chronic obstructive pulmonary disease. Reynolds, Corey L; Zhang, Shaojie; Shrestha, Amrit Kumar; Barrios, Roberto; Shivanna, Binoy International journal of chronic obstructive pulmonary disease. 27478373 2016;
Cryorecovery of Mouse Sperm by Different IVF Methods Using MBCD and GSH. Li, Ming-Wen; Glass, Olivia C; Zarrabi, Jasmin; Baker, Lisa N; Lloyd, K C Kent Journal of fertilization in vitro. 27413624 2016 May;
Evaluating the Effects of Riboflavin/UV-A and Rose-Bengal/Green Light Cross-Linking of the Rabbit Cornea by Noncontact Optical Coherence Elastography. Singh, Manmohan; Li, Jiasong; Han, Zhaolong; Vantipalli, Srilatha; Liu, Chih-Hao; Wu, Chen; Raghunathan, Raksha; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill V Investigative ophthalmology & visual science. 27409461 2016 07 01;
Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR. Haeussler, Maximilian; Schönig, Kai; Eckert, Hélène; Eschstruth, Alexis; Mianné, Joffrey; Renaud, Jean-Baptiste; Schneider-Maunoury, Sylvie; Shkumatava, Alena; Teboul, Lydia; Kent, Jim; Joly, Jean-Stephane; Concordet, Jean-Paul Genome biology. 27380939 2016 Jul 05;
Applicability, usability, and limitations of murine embryonic imaging with optical coherence tomography and optical projection tomography. Singh, Manmohan; Raghunathan, Raksha; Piazza, Victor; Davis-Loiacono, Anjul M; Cable, Alex; Vedakkan, Tegy J; Janecek, Trevor; Frazier, Michael V; Nair, Achuth; Wu, Chen; Larina, Irina V; Dickinson, Mary E; Larin, Kirill V Biomedical optics express. 27375945 2016 Jun 01;
Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury. Tao, Ge; Kahr, Peter C; Morikawa, Yuka; Zhang, Min; Rahmani, Mahdis; Heallen, Todd R; Li, Lele; Sun, Zhao; Olson, Eric N; Amendt, Brad A; Martin, James F Nature. 27251288 2016 Jun 2;
CRIPT exonic deletion and a novel missense mutation in a female with short stature, dysmorphic features, microcephaly, and pigmentary abnormalities. Leduc, Magalie S; Niu, Zhiyv; Bi, Weimin; Zhu, Wenmiao; Miloslavskaya, Irene; Chiang, Theodore; Streff, Haley; Seavitt, John R; Murray, Stephen A; Eng, Christine; Chan, Audrey; Yang, Yaping; Lalani, Seema R American journal of medical genetics. Part A. 27250922 2016 Aug;
Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy. Madeo, Marianna; Stewart, Michelle; Sun, Yuyang; Sahir, Nadia; Wiethoff, Sarah; Chandrasekar, Indra; Yarrow, Anna; Rosenfeld, Jill A; Yang, Yaping; Cordeiro, Dawn; McCormick, Elizabeth M; Muraresku, Colleen C; Jepperson, Tyler N; McBeth, Lauren J; Seidahmed, Mohammed Zain; El Khashab, Heba Y; Hamad, Muddathir; Azzedine, Hamid; Clark, Karl; Corrochano, Silvia; Wells, Sara; Elting, Mariet W; Weiss, Marjan M; Burn, Sabrina; Myers, Angela; Landsverk, Megan; Crotwell, Patricia L; Waisfisz, Quinten; Wolf, Nicole I; Nolan, Patrick M; Padilla-Lopez, Sergio; Houlden, Henry; Lifton, Richard; Mane, Shrikant; Singh, Brij B; Falk, Marni J; Mercimek-Mahmutoglu, Saadet; Bilguvar, Kaya; Salih, Mustafa A; Acevedo-Arozena, Abraham; Kruer, Michael C American journal of human genetics. 27236917 2016 Jun 2;
Optical coherence tomography for embryonic imaging: a review. Raghunathan, Raksha; Singh, Manmohan; Dickinson, Mary E; Larin, Kirill V Journal of biomedical optics. 27228503 2016 May 01;
Rapid, noninvasive quantitation of skin disease in systemic sclerosis using optical coherence elastography. Du, Yong; Liu, Chih-Hao; Lei, Ling; Singh, Manmohan; Li, Jiasong; Hicks, M John; Larin, Kirill V; Mohan, Chandra Journal of biomedical optics. 27048877 2016 Apr 30;
Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice. Shaheen, Ranad; Anazi, Shams; Ben-Omran, Tawfeg; Seidahmed, Mohammed Zain; Caddle, L Brianna; Palmer, Kristina; Ali, Rehab; Alshidi, Tarfa; Hagos, Samya; Goodwin, Leslie; Hashem, Mais; Wakil, Salma M; Abouelhoda, Mohamed; Colak, Dilek; Murray, Stephen A; American journal of human genetics. 27018474 2016 Apr 7;
Four-dimensional live imaging of hemodynamics in mammalian embryonic heart with Doppler optical coherence tomography. Wang, Shang; Lakomy, David S; Garcia, Monica D; Lopez 3rd, Andrew L; Larin, Kirill V; Larina, Irina V Journal of biophotonics. 26996292 2016 Aug;
Optical coherence tomography as a tool for real-time visual feedback and biomechanical assessment of dermal filler injections: preliminary results in a pig skin model. Singh, Manmohan; Wang, Shang; Yee, Richard W; Larin, Kirill V Experimental dermatology. 26910121 2016 06;
Reporting phenotypes in mouse models when considering body size as a potential confounder. Oellrich, Anika; Meehan, Terrence F; Parkinson, Helen; Sarntivijai, Sirarat; White, Jacqueline K; Karp, Natasha A Journal of biomedical semantics 26865945 2016
Rotational imaging optical coherence tomography for full-body mouse embryonic imaging. Wu, Chen; Sudheendran, Narendran; Singh, Manmohan; Larina, Irina V; Dickinson, Mary E; Larin, Kirill V Journal of biomedical optics. 26848543 2016 Feb;
Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. West, David B; Engelhard, Eric K; Adkisson, Michael; Nava, A J; Kirov, Julia V; Cipollone, Andreanna; Willis, Brandon; Rapp, Jared; de Jong, Pieter J; Lloyd, Kent C PLoS genetics. 26839965 2016 Feb;
Classifying murine glomerulonephritis using optical coherence tomography and optical coherence elastography. Liu, Chih-Hao; Du, Yong; Singh, Manmohan; Wu, Chen; Han, Zhaolong; Li, Jiasong; Chang, Anthony; Mohan, Chandra; Larin, Kirill V Journal of biophotonics. 26791097 2016 Aug;
Chromosome engineering in zygotes with CRISPR/Cas9. Boroviak, Katharina; Doe, Brendan; Banerjee, Ruby; Yang, Fengtang; Bradley, Allan Genesis (New York, N.Y. : 2000). 26742453 2016 Feb;
Yap and Taz play a crucial role in neural crest-derived craniofacial development. Wang, Jun; Xiao, Yang; Hsu, Chih-Wei; Martinez-Traverso, Idaliz M; Zhang, Min; Bai, Yan; Ishii, Mamoru; Maxson, Robert E; Olson, Eric N; Dickinson, Mary E; Wythe, Joshua D; Martin, James F Development (Cambridge, England). 26718006 2016 Feb 1;
Precision medicine: an opportunity for a paradigm shift in veterinary medicine. Lloyd, K C Kent; Khanna, Chand; Hendricks, William; Trent, Jeffrey; Kotlikoff, Michael Journal of the American Veterinary Medical Association 26684088 2016 Jan 1
JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Berg, Jamee M; Lee, Changhoon; Chen, Leslie; Galvan, Laurie; Cepeda, Carlos; Chen, Jane Y; Peñagarikano, Olga; Stein, Jason L; Li, Alvin; Oguro-Ando, Asami; Miller, Jeremy A; Vashisht, Ajay A; Starks, Mary E; Kite, Elyse P; Tam, Eric; Gdalyahu, Amos; Al-S Neuron. 26627310 2015 Dec 16;
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency. Bone, William P; Washington, Nicole L; Buske, Orion J; Adams, David R; Davis, Joie; Draper, David; Flynn, Elise D; Girdea, Marta; Godfrey, Rena; Golas, Gretchen; Groden, Catherine; Jacobsen, Julius; Köhler, Sebastian; Lee, Elizabeth M J; Links, Amanda E; Markello, Thomas C; Mungall, Christopher J; Nehrebecky, Michele; Robinson, Peter N; Sincan, Murat; Soldatos, Ariane G; Tifft, Cynthia J; Toro, Camilo; Trang, Heather; Valkanas, Elise; Vasilevsky, Nicole; Wahl, Colleen; Wolfe, Lynne A; Boerkoel, Cornelius F; Brudno, Michael; Haendel, Melissa A; Gahl, William A; Smedley, Damian Genetics in medicine : official journal of the American College of Medical Genetics. 26562225 2016 Jun;
Excavating the Genome: Large-Scale Mutagenesis Screening for the Discovery of New Mouse Models. Sundberg, John P; Dadras, Soheil S; Silva, Kathleen A; Kennedy, Victoria E; Murray, Stephen A; Denegre, James M; Schofield, Paul N; King Jr, Lloyd E; Wiles, Michael V; Pratt, C Herbert The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. 26551941 2015 Nov;
Scaling up phenotyping studies. Svenson, Karen L Nature biotechnology. 26544146 2015 Nov;
4D atlas of the mouse embryo for precise morphological staging. Wong, Michael D; van Eede, Matthijs C; Spring, Shoshana; Jevtic, Stefan; Boughner, Julia C; Lerch, Jason P; Henkelman, R Mark Development (Cambridge, England). 26487781 2015 Oct 15;
Direct four-dimensional structural and functional imaging of cardiovascular dynamics in mouse embryos with 1.5 MHz optical coherence tomography. Wang, Shang; Singh, Manmohan; Lopez 3rd, Andrew L; Wu, Chen; Raghunathan, Raksha; Schill, Alexander; Li, Jiasong; Larin, Kirill V; Larina, Irina V Optics letters. 26469621 2015 Oct 15;
Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration. Zhao, Lihong; Spassieva, Stefka; Gable, Kenneth; Gupta, Sita D; Shi, Lan-Ying; Wang, Jieping; Bielawski, Jacek; Hicks, Wanda L; Krebs, Mark P; Naggert, Juergen; Hannun, Yusuf A; Dunn, Teresa M; Nishina, Patsy M Proceedings of the National Academy of Sciences of the United States of America. 26438849 2015 Oct 20;
MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates. Guimier, Anne; Gabriel, George C; Bajolle, Fanny; Tsang, Michael; Liu, Hui; Noll, Aaron; Schwartz, Molly; El Malti, Rajae; Smith, Laurie D; Klena, Nikolai T; Jimenez, Gina; Miller, Neil A; Oufadem, Myriam; Moreau de Bellaing, Anne; Yagi, Hisato; Saunders, Carol J; Baker, Candice N; Di Filippo, Sylvie; Peterson, Kevin A; Thiffault, Isabelle; Bole-Feysot, Christine; Cooley, Linda D; Farrow, Emily G; Masson, Cécile; Schoen, Patric; Deleuze, Jean-François; Nitschké, Patrick; Lyonnet, Stanislas; de Pontual, Loic; Murray, Stephen A; Bonnet, Damien; Kingsmore, Stephen F; Amiel, Jeanne; Bouvagnet, Patrice; Lo, Cecilia W; Gordon, Christopher T Nature genetics. 26437028 2015 Nov;
Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance. Hugill, Alison J; Stewart, Michelle E; Yon, Marianne A; Probert, Fay; Cox, I Jane; Hough, Tertius A; Scudamore, Cheryl L; Bentley, Liz; Wall, Gary; Wells, Sara E; Cox, Roger D Biology open. 26432886 2015 Oct 02;
The digital revolution in phenotyping. Oellrich, Anika; Collier, Nigel; Groza, Tudor; Rebholz-Schuhmann, Dietrich; Shah, Nigam; Bodenreider, Olivier; Boland, Mary Regina; Georgiev, Ivo; Liu, Hongfang; Livingston, Kevin; Luna, Augustin; Mallon, Ann-Marie; Manda, Prashanti; Robinson, Peter N; Rustici, Gabriella; Simon, Michelle; Wang, Liqin; Winnenburg, Rainer; Dumontier, Michel Briefings in bioinformatics. 26420780 2016 09;
A gene expression resource generated by genome-wide lacZ profiling in the mouse. Tuck, Elizabeth; Estabel, Jeanne; Oellrich, Anika; Maguire, Anna Karin; Adissu, Hibret A; Souter, Luke; Siragher, Emma; Lillistone, Charlotte; Green, Angela L; Wardle-Jones, Hannah; Carragher, Damian M; Karp, Natasha A; Smedley, Damian; Adams, Niels C; Sa Disease models & mechanisms. 26398943 2015 Nov;
Live four-dimensional optical coherence tomography reveals embryonic cardiac phenotype in mouse mutant. Lopez 3rd, Andrew L; Wang, Shang; Larin, Kirill V; Overbeek, Paul A; Larina, Irina V Journal of biomedical optics. 26385422 2015;
Cardiovascular Patterning as Determined by Hemodynamic Forces and Blood Vessel Genetics. Anderson, Gregory A; Udan, Ryan S; Dickinson, Mary E; Henkelman, R Mark PloS one. 26340748 2015;
A mouse informatics platform for phenotypic and translational discovery. Ring, Natalie; Meehan, Terrence F; Blake, Andrew; Brown, James; Chen, Chao-Kung; Conte, Nathalie; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Jacobsen, Julius O B; Karp, Natasha; Lawson, Thomas; Mason, Jeremy C; Matthews, Peter; Morgan, Hugh; Relac, Mi Mammalian genome : official journal of the International Mammalian Genome Society. 26314589 2015 Oct;
In vivo micro-scale tomography of ciliary behavior in the mammalian oviduct. Wang, Shang; Burton, Jason C; Behringer, Richard R; Larina, Irina V Scientific reports. 26279472 2015;
Reporter Gene Silencing in Targeted Mouse Mutants Is Associated with Promoter CpG Island Methylation. Kirov, Julia V; Adkisson, Michael; Nava, A J; Cipollone, Andreana; Willis, Brandon; Engelhard, Eric K; Lloyd, K C Kent; de Jong, Pieter; West, David B PloS one. 26275310 2015;
Comparative visualization of genotype-phenotype relationships. Yaikhom, Gagarine; Morgan, Hugh; Sneddon, Duncan; Retha, Ahmad; Atienza-Herrero, Julian; Blake, Andrew; Brown, James; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Ring, Natalie; Santos, Luis; Westerberg, Henrik; Brown, Steve D M; Mallon, Ann-Marie Nature methods. 26226357 2015 Aug;
Principles and application of LIMS in mouse clinics. Maier, Holger; Schütt, Christine; Steinkamp, Ralph; Hurt, Anja; Schneltzer, Elida; Gormanns, Philipp; Lengger, Christoph; Griffiths, Mark; Melvin, David; Agrawal, Neha; Alcantara, Rafael; Evans, Arthur; Gannon, David; Holroyd, Simon; Kipp, Christian; Raj, Mammalian genome : official journal of the International Mammalian Genome Society. 26208973 2015 Oct;
Precision medicine: Look to the mice. Lloyd, K C Kent; Meehan, Terry; Beaudet, Arthur; Murray, Steve; Svenson, Karen; McKerlie, Colin; West, David; Morse, Iva; Parkinson, Helen; Brown, Steve; Mallon, Ann-Marie; Moore, Mark Science (New York, N.Y.). 26206923 2015 Jul 24;
High-resolution three-dimensional in vivo imaging of mouse oviduct using optical coherence tomography. Burton, Jason C; Wang, Shang; Stewart, C Allison; Behringer, Richard R; Larina, Irina V Biomedical optics express. 26203393 2015 Jul 1;
PhenStat: A Tool Kit for Standardized Analysis of High Throughput Phenotypic Data. Kurbatova, Natalja; Mason, Jeremy C; Morgan, Hugh; Meehan, Terrence F; Karp, Natasha A PloS one. 26147094 2015;
Analysis of the effects of curvature and thickness on elastic wave velocity in cornea-like structures by finite element modeling and optical coherence elastography. Han, Zhaolong; Li, Jiasong; Singh, Manmohan; Aglyamov, Salavat R; Wu, Chen; Liu, Chih-Hao; Larin, Kirill V Applied physics letters. 26130825 2015 Jun 08;
Disease insights through cross-species phenotype comparisons. Haendel, Melissa A; Vasilevsky, Nicole; Brush, Matthew; Hochheiser, Harry S; Jacobsen, Julius; Oellrich, Anika; Mungall, Christopher J; Washington, Nicole; Köhler, Sebastian; Lewis, Suzanna E; Robinson, Peter N; Smedley, Damian Mammalian genome : official journal of the International Mammalian Genome Society. 26092691 2015 Oct;
Reproducibility: use mouse biobanks or lose them. Lloyd, Kent; Franklin, Craig; Lutz, Cat; Magnuson, Terry Nature. 26062496 2015 Jun 11;
Phase-sensitive optical coherence elastography at 1.5 million A-Lines per second. Singh, Manmohan; Wu, Chen; Liu, Chih-Hao; Li, Jiasong; Schill, Alexander; Nair, Achuth; Larin, Kirill V Optics letters. 26030564 2015 Jun 1;
Applying the ARRIVE Guidelines to an In Vivo Database. Karp, Natasha A; Meehan, Terry F; Morgan, Hugh; Mason, Jeremy C; Blake, Andrew; Kurbatova, Natalja; Smedley, Damian; Jacobsen, Julius; Mott, Richard F; Iyer, Vivek; Matthews, Peter; Melvin, David G; Wells, Sara; Flenniken, Ann M; Masuya, Hiroshi; Wakana, Shigeharu; White, Jacqueline K; Lloyd, K C Kent; Reynolds, Corey L; Paylor, Richard; West, David B; Svenson, Karen L; Chesler, Elissa J; de Angelis, Martin Hrab?; Tocchini-Valentini, Glauco P; Sorg, Tania; Herault, Yann; Parkinson, Helen; Mallon, Ann-Marie; Brown, Steve D M PLoS biology. 25992600 2015 May;
CRISPR-Cas9-mediated genome editing and guide RNA design. Wiles, Michael V; Qin, Wenning; Cheng, Albert W; Wang, Haoyi Mammalian genome : official journal of the International Mammalian Genome Society. 25991564 2015 Oct;
WGE: a CRISPR database for genome engineering. Hodgkins, Alex; Farne, Anna; Perera, Sajith; Grego, Tiago; Parry-Smith, David J; Skarnes, William C; Iyer, Vivek Bioinformatics (Oxford, England). 25979474 2015 Sep 15;
Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice. Morikawa, Yuka; Zhang, Min; Heallen, Todd; Leach, John; Tao, Ge; Xiao, Yang; Bai, Yan; Li, Wei; Willerson, James T; Martin, James F Science signaling. 25943351 2015 May 5;
Linking gene expression to phenotypes via pathway information. Papatheodorou, Irene; Oellrich, Anika; Smedley, Damian Journal of biomedical semantics. 25901272 2015;
Quantitative methods for reconstructing tissue biomechanical properties in optical coherence elastography: a comparison study. Han, Zhaolong; Li, Jiasong; Singh, Manmohan; Wu, Chen; Liu, Chih-hao; Wang, Shang; Idugboe, Rita; Raghunathan, Raksha; Sudheendran, Narendran; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill V Physics in medicine and biology. 25860076 2015 May 7;
Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening. Gurumurthy, Channabasavaiah B; Joshi, Poonam S; Kurz, Scott G; Ohtsuka, Masato; Quadros, Rolen M; Harms, Donald W; Lloyd, K C Kent International journal of genomics. 25815306 2015;
Automatic concept recognition using the human phenotype ontology reference and test suite corpora. Groza, Tudor; Köhler, Sebastian; Doelken, Sandra; Collier, Nigel; Oellrich, Anika; Smedley, Damian; Couto, Francisco M; Baynam, Gareth; Zankl, Andreas; Robinson, Peter N Database : the journal of biological databases and curation. 25725061 2015;
Algorithms for improved 3-D reconstruction of live mammalian embryo vasculature from optical coherence tomography data. Kulkarni, Prathamesh M; Rey-Villamizar, Nicolas; Merouane, Amine; Sudheendran, Narendran; Wang, Shang; Garcia, Monica; Larina, Irina V; Roysam, Badrinath; Larin, Kirill V Quantitative imaging in medicine and surgery. 25694962 2015 Feb;
Quantitative assessment of corneal viscoelasticity using optical coherence elastography and a modified Rayleigh-Lamb equation. Han, Zhaolong; Aglyamov, Salavat R; Li, Jiasong; Singh, Manmohan; Wang, Shang; Vantipalli, Srilatha; Wu, Chen; Liu, Chih-Hao; Twa, Michael D; Larin, Kirill V Journal of biomedical optics. 25649624 2015 Feb;
Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds. Yang, Jie; Wang, Shih-Kai; Choi, Murim; Reid, Bryan M; Hu, Yuanyuan; Lee, Yuan-Ling; Herzog, Curtis R; Kim-Berman, Hera; Lee, Moses; Benke, Paul J; Lloyd, K C Kent; Simmer, James P; Hu, Jan C-C Molecular genetics & genomic medicine. 25629078 2015 Jan;
Generation of silver standard concept annotations from biomedical texts with special relevance to phenotypes. Oellrich, Anika; Collier, Nigel; Smedley, Damian; Groza, Tudor PloS one. 25607983 2015;
A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines. West, David B; Pasumarthi, Ravi K; Baridon, Brian; Djan, Esi; Trainor, Amanda; Griffey, Stephen M; Engelhard, Eric K; Rapp, Jared; Li, Bowen; de Jong, Pieter J; Lloyd, K C Kent Genome research. 25591789 2015 Apr;
Optical coherence tomography guided microinjections in live mouse embryos: high-resolution targeted manipulation for mouse embryonic research. Syed, Saba H; Coughlin, Andrew J; Garcia, Monica D; Wang, Shang; West, Jennifer L; Larin, Kirill V; Larina, Irina V Journal of biomedical optics. 25581495 2015 May;
A common control group - optimising the experiment design to maximise sensitivity. Bate, Simon; Karp, Natasha A PloS one. 25504147 2014;
Noncontact depth-resolved micro-scale optical coherence elastography of the cornea. Wang, Shang; Larin, Kirill V Biomedical optics express. 25426312 2014 Nov 01;
Optical coherence elastography for tissue characterization: a review. Wang, Shang; Larin, Kirill V Journal of biophotonics. 25412100 2015 Apr;
Differentiating untreated and cross-linked porcine corneas of the same measured stiffness with optical coherence elastography. Li, Jiasong; Han, Zhaolong; Singh, Manmohan; Twa, Michael D; Larin, Kirill V Journal of biomedical optics. 25408955 2014 Nov;
Impact of temporal variation on design and analysis of mouse knockout phenotyping studies. Karp, Natasha A; Speak, Anneliese O; White, Jacqueline K; Adams, David J; Hrabe de Angelis, Martin; Herault, Yann; Mott, Richard F PloS one. 25343444 2014;
Right Ventricular Epicardial Fibrosis in Mice With Sternal Segment Dislocation. Adissu, H A; Medhanie, G A; Morikawa, L; White, J K; Newbigging, S; McKerlie, C Veterinary pathology. 25281652 2014 Oct 3;
A lymphatic defect causes ocular hypertension and glaucoma in mice. Thomson, Benjamin R; Heinen, Stefan; Jeansson, Marie; Ghosh, Asish K; Fatima, Anees; Sung, Hoon-Ki; Onay, Tuncer; Chen, Hui; Yamaguchi, Shinji; Economides, Aris N; Flenniken, Ann; Gale, Nicholas W; Hong, Young-Kwon; Fawzi, Amani; Liu, Xiaorong; Kume, Tsut The Journal of clinical investigation. 25202984 2014 Oct;
Vascular development and hemodynamic force in the mouse yolk sac. Garcia, Monica D; Larina, Irina V Frontiers in physiology. 25191274 2014;
Conditional targeting of Ispd using paired Cas9 nickase and a single DNA template in mice. Lee, Angus Yiu-Fai; Lloyd, Kevin C Kent FEBS open bio. 25161872 2014;
Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia. Salsbury, Grace; Cambridge, Emma L; McIntyre, Zoe; Arends, Mark J; Karp, Natasha A; Isherwood, Christopher; Shannon, Carl; Hooks, Yvette; Sanger Mouse Genetics Project; Ramirez-Solis, Ramiro; Adams, David J; White, Jacqueline K; Speak, Anneliese O Experimental hematology. 25127743 2014 Dec;
Rescue of germline transmission from chimeras by IVF after sperm analysis. Li, Ming-Wen; Willis, Brandon J; Evans, Kristin D; Araiza, Renee S; Lee, Angus Yiu-Fai; Lloyd, K C Kent Transgenic research. 25080098 2015 Feb;
Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. Hopkins, Jessica; Hwang, Grace; Jacob, Justin; Sapp, Nicklas; Bedigian, Rick; Oka, Kazuhiro; Overbeek, Paul; Murray, Steve; Jordan, Philip W PLoS genetics. 24992337 2014 Jul;
Using association rule mining to determine promising secondary phenotyping hypotheses. Oellrich, Anika; Jacobsen, Julius; Papatheodorou, Irene; Sanger Mouse Genetics Project; Smedley, Damian Bioinformatics (Oxford, England) 24932005 2014 Jun 15
IVF recovery of mutant mouse lines using sperm cryopreserved with mtg in cryovials. Li, Ming-Wen; Vallelunga, Jadine M; Kinchen, Kristy L; Rink, Karina L; Zarrabi, Jasmin; Shamamian, Armen O; Lloyd, K C Kent Cryo letters 24869647 2014 Mar-Apr
Automated pipeline for anatomical phenotyping of mouse embryos using micro-CT. Wong, Michael D; Maezawa, Yoshiro; Lerch, Jason P; Henkelman, R Mark Development (Cambridge, England) 24850858 2014 Jun
Animal models: Mouse already being charted gene by gene. Brown, Steve Nature. 24740057 2014 Apr 17;
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Adissu, Hibret A; Estabel, Jeanne; Sunter, David; Tuck, Elizabeth; Hooks, Yvette; Carragher, Damian M; Clarke, Kay; Karp, Natasha A; Sanger Mouse Genetics Project; Newbigging, Susan; Jones, Nora; Morikawa, Lily; White, Jacqueline K; McKerlie, Colin Disease models & mechanisms 24652767 2014 May
Linking tissues to phenotypes using gene expression profiles. Oellrich, Anika; Sanger Mouse Genetics Project; Smedley, Damian Database : the journal of biological databases and curation 24634472 2014
Special section guest editorial: Optical coherence tomography and interferometry: advanced engineering and biomedical applications. Larin, Kirill V; Tuchin, Valery V; Vitkin, Alex Journal of biomedical optics 24570205 2014
Structural stabilization of tissue for embryo phenotyping using micro-CT with iodine staining. Wong, Michael D; Spring, Shoshana; Henkelman, R Mark PloS one. 24386367 2013;
Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides. Takeo, Toru; Fukumoto, Kiyoko; Kondo, Tomoko; Haruguchi, Yukie; Takeshita, Yumi; Nakamuta, Yuko; Tsuchiyama, Shuuji; Yoshimoto, Hidetaka; Shimizu, Norihiko; Li, Ming-Wen; Kinchen, Kristy; Vallelunga, Jadine; Lloyd, K C Kent; Nakagata, Naomi Cryobiology 24201107 2014 Feb
Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase. Ryder, Edward; Doe, Brendan; Gleeson, Diane; Houghton, Richard; Dalvi, Priya; Grau, Evelyn; Habib, Bishoy; Miklejewska, Evelina; Newman, Stuart; Sethi, Debarati; Sinclair, Caroline; Vyas, Sapna; Wardle-Jones, Hannah; Sanger Mouse Genetics Project; Bottoml Transgenic research 24197666 2014 Feb
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny, Gautier; Yaikhom, Gagarine; Iyer, Vivek; Meehan, Terrence F; Morgan, Hugh; Atienza-Herrero, Julian; Blake, Andrew; Chen, Chao-Kung; Easty, Richard; Di Fenza, Armida; Fiegel, Tanja; Grifiths, Mark; Horne, Alan; Karp, Natasha A; Kurbatova, Natalj Nucleic acids research 24194600 2014 Jan
Sestrin-2, a repressor of PDGFR* signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD. Heidler, Juliana; Fysikopoulos, Athanasios; Wempe, Frank; Seimetz, Michael; Bangsow, Thorsten; Tomasovic, Ana; Veit, Florian; Scheibe, Susan; Pichl, Alexandra; Weisel, Friederike; Lloyd, K C Kent; Jaksch, Peter; Klepetko, Walter; Weissmann, Norbert; von M Disease models & mechanisms 24046361 2013 Nov
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL). Carofino, Brandi L; Ayanga, Bernard; Justice, Monica J Disease models & mechanisms 24046360 2013 Nov
The mouse pathology ontology, MPATH; structure and applications. Schofield, Paul N; Sundberg, John P; Sundberg, Beth A; McKerlie, Colin; Gkoutos, Georgios V Journal of biomedical semantics 24033988 2013
Design and implementation of a custom built optical projection tomography system. Wong, Michael D; Dazai, Jun; Walls, Johnathon R; Gale, Nicholas W; Henkelman, R Mark PloS one. 24023880 2013;
Combining sperm plug genotyping and coat color chimerism predicts germline transmission. Lee, Angus Yiu-Fai; Evans, Kristin; Willis, Brandon; Lloyd, K C Kent Transgenic research 23860911 2013 Jul 17
The perfect host: a mouse host embryo facilitating more efficient germ line transmission of genetically modified embryonic stem cells. Taft, Robert A; Low, Benjamin E; Byers, Shannon L; Murray, Stephen A; Kutny, Peter; Wiles, Michael V PloS one. 23844102 2013;
Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening. Adams, David; Baldock, Richard; Bhattacharya, Shoumo; Copp, Andrew J; Dickinson, Mary; Greene, Nicholas D E; Henkelman, Mark; Justice, Monica; Mohun, Timothy; Murray, Stephen A; Pauws, Erwin; Raess, Michael; Rossant, Janet; Weaver, Tom; West, David Disease models & mechanisms 23828646 2013 Jul-Aug
Mapping registration sensitivity in MR mouse brain images. van Eede, Matthijs C; Scholz, Jan; Chakravarty, M Mallar; Henkelman, R Mark; Lerch, Jason P NeuroImage. 23756204 2013 Nov 15;
Effect of different cryoprotectant agents on spermatogenesis efficiency in cryopreserved and grafted neonatal mouse testicular tissue. Yildiz, Cengiz; Mullen, Brendan; Jarvi, Keith; McKerlie, Colin; Lo, Kirk C Cryobiology 23721968 2013 Aug
Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening. Adams, David; Baldock, Richard; Bhattacharya, Shoumo; Copp, Andrew J; Dickinson, Mary; Greene, Nicholas D E; Henkelman, Mark; Justice, Monica; Mohun, Timothy; Murray, Stephen A; Pauws, Erwin; Raess, Michael; Rossant, Janet; Weaver, Tom; West, David Disease models & mechanisms 23519032 2013 May
3D imaging, registration, and analysis of the early mouse embryonic vasculature. Anderson, Gregory A; Wong, Michael D; Yang, Jian; Henkelman, R Mark Developmental dynamics : an official publication of the American Association of Anatomists. 23417982 2013 May;
High osmolality vitrification: a new method for the simple and temperature-permissive cryopreservation of mouse embryos. Mochida, Keiji; Hasegawa, Ayumi; Li, Ming-Wen; Fray, Martin D; Kito, Seiji; Vallelunga, Jadine M; Lloyd, K C Kent; Yoshiki, Atsushi; Obata, Yuichi; Ogura, Atsuo PloS one. 23341870 2013;
Safety, efficacy and efficiency of laser-assisted IVF in subfertile mutant mouse strains. Li, Ming-Wen; Kinchen, Kristy L; Vallelunga, Jadine M; Young, Diana L; Wright, Kaleb D K; Gorano, Lisa N; Wasson, Katherine; Lloyd, K C Kent Reproduction (Cambridge, England) 23315689 2013 Mar
Robust and sensitive analysis of mouse knockout phenotypes. Karp, Natasha A; Melvin, David; Sanger Mouse Genetics Project; Mott, Richard F PloS one 23300663 2012
Accessing and mining data from large-scale mouse phenotyping projects. Morgan, Hugh; Simon, Michelle; Mallon, Ann-Marie International review of neurobiology 23195311 2012
Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left-right patterning and heart development. Jiang, Zhengxin; Zhu, Lirong; Hu, Lingyun; Slesnick, Timothy C; Pautler, Robia G; Justice, Monica J; Belmont, John W Human molecular genetics 23184148 2013 Mar 1
Preclinical research in Rett syndrome: setting the foundation for translational success. Katz, David M; Berger-Sweeney, Joanne E; Eubanks, James H; Justice, Monica J; Neul, Jeffrey L; Pozzo-Miller, Lucas; Blue, Mary E; Christian, Diana; Crawley, Jacqueline N; Giustetto, Maurizio; Guy, Jacky; Howell, C James; Kron, Miriam; Nelson, Sacha B; Samaco, Rodney C; Schaevitz, Laura R; St Hillaire-Clarke, Coryse; Young, Juan L; Zoghbi, Huda Y; Mamounas, Laura A Disease models & mechanisms 23115203 2012 Nov
Structural and functional concepts in current mouse phenotyping and archiving facilities. Kollmus, Heike; Post, Rainer; Brielmeier, Markus; Fernandez, Julia; Fuchs, Helmut; McKerlie, Colin; Montoliu, Lluis; Otaegui, Pedro J; Rebelo, Manuel; Riedesel, Hermann; Ruberte, Jesus; Sedlacek, Radislav; de Angelis, Martin Hrabe; Schughart, Klaus Journal of the American Association for Laboratory Animal Science : JAALAS 23043807 2012 Jul
Immunohistochemical analysis of sphingosine phosphate lyase expression during murine development. Newbigging, Susan; Zhang, Meng; Saba, Julie D Gene expression patterns : GEP. 23041657 2013 Jan-Feb;
Genetically Engineered Mice by Pronuclear DNA microinjection. Demayo, Janet L; Wang, Jie; Liang, Dongcai; Zhang, Ruina; Demayo, Francesco J Current protocols in mouse biology 23024927 2012 Sep 1
Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans. Mallon AM, Iyer V, Melvin D, Morgan H, Parkinson H, Brown SD, Flicek P, Skarnes WC. Mamm Genome 22991088 2012 Oct
The mammalian gene function resource: the international knockout mouse consortium. Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, et al. Mamm Genome 22968824 2012 Oct
The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data. Smith CL, Eppig JT. Mamm Genome 22961259 2012 Oct
Centralized mouse repositories. Donahue, Leah Rae; Hrabe de Angelis, Martin; Hagn, Michael; Franklin, Craig; Lloyd, K C Kent; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Horlein, Andreas; Davisson, Muriel T Mammalian genome : official journal of the International Mammalian Genome Society 22945696 2012 Oct
The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping. Brown SD, Moore MW. Mamm Genome 22940749 2012 Oct
Beyond knockouts: cre resources for conditional mutagenesis. Murray SA, Eppig JT, Smedley D, Simpson EM, Rosenthal N. Mamm Genome 22926223 2012 Oct
A novel 3D mouse embryo atlas based on micro-CT. Wong, Michael D; Dorr, Adrienne E; Walls, Johnathon R; Lerch, Jason P; Henkelman, R Mark Development (Cambridge, England). 22872090 2012 Sep;
Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues. Borowsky, Alexander D; Bandhuvula, Padmavathi; Kumar, Ashok; Yoshinaga, Yuko; Nefedov, Mikhail; Fong, Loren G; Zhang, Meng; Baridon, Brian; Dillard, Lisa; de Jong, Pieter; Young, Stephen G; West, David B; Saba, Julie D Journal of lipid research 22781001 2012 Sep
Neuroanatomical phenotyping of the mouse brain with three-dimensional autofluorescence imaging. Gleave, Jacqueline A; Wong, Michael D; Dazai, Jun; Altaf, Maliha; Henkelman, R Mark; Lerch, Jason P; Nieman, Brian J Physiological genomics. 22718750 2012 Aug 1;
The role of sphingosine-1-phosphate transporter Spns2 in immune system function. Nijnik A, Clare S, Hale C, Chen J, Raisen C, Mottram L, Lucas M, Estabel J, Ryder E, Adissu H; Sanger Mouse Genetics Project, Adams NC, Ramirez-Solis R, White JK, Steel KP, Dougan G, Hancock RE. J Immunol 22664872 2012 Jul 1
Mutant mice derived by ICSI of evaporatively dried spermatozoa exhibit expected phenotype. Li, Ming-Wen; Baridon, Brian; Trainor, Amanda; Djan, Esi; Koehne, Amanda; Griffey, Stephen M; Biggers, John D; Toner, Mehmet; Lloyd, K C Kent Reproduction (Cambridge, England). 22274886 2012 Apr;
A knockout mouse resource for the biomedical research community. Lloyd KC. Ann N Y Acad Sci 22211970 2011 Dec
Optical Coherence Tomography for live imaging of mammalian development. Larina IV, Larin KV, Justice MJ, Dickinson ME. Curr Opin Genet Dev 21962442 2011 Oct
Rederivation of transgenic mice from iPS cells derived from frozen tissue. Lee, Angus Yiu-Fai; Lloyd, K C Kent Transgenic research. 20397045 2011 Feb;

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