Regulatory Science
Regulatory Science
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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
| Title | Author | Journal Name | PubMedID | Journal Abbreviation | Publication Date |
|---|---|---|---|---|---|
| Human fallopian tube epithelium co-culture with murine ovarian follicles reveals crosstalk in the reproductive cycle. | Zhu J, Xu Y, Rashedi AS, Pavone ME, Kim JJ, Woodruff TK, Burdette JE | Molecular human reproduction | 27542947 | Mol Hum Reprod | 2016 Nov |
| Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface. | Karthikeyan S, Lantvit DD, Chae DH, Burdette JE | Oncotarget | 27563818 | Oncotarget | 2016 Oct 25 |
| Extra Cellular Matrix-Based and Extra Cellular Matrix-Free Generation of Murine Testicular Organoids. | Edmonds ME, Forshee MD, Woodruff TK | Journal of visualized experiments : JoVE | 33104061 | J Vis Exp | 2020 Oct 7 |
| A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control. | Coppeta JR, Mescher MJ, Isenberg BC, Spencer AJ, Kim ES, Lever AR, Mulhern TJ, Prantil-Baun R, Comolli JC, Borenstein JT | Lab on a chip | 27901159 | Lab Chip | 2016 Dec 20 |
| A Systematic Evaluation of Factors Affecting Extracellular Vesicle Uptake by Breast Cancer Cells. | Stranford DM, Hung ME, Gargus ES, Shah RN, Leonard JN | Tissue engineering. Part A | 28586292 | Tissue Eng Part A | 2017 Nov |
| Engineering the ovarian cycle using in vitro follicle culture. | Skory RM, Xu Y, Shea LD, Woodruff TK | Human reproduction (Oxford, England) | 25784584 | Hum Reprod | 2015 Jun |
| Three-dimensional modeling of the human fallopian tube fimbriae. | Eddie SL, Quartuccio SM, Zhu J, Shepherd JA, Kothari R, Kim JJ, Woodruff TK, Burdette JE | Gynecologic oncology | 25527363 | Gynecol Oncol | 2015 Feb |
| Testicular organoid formation is a property of immature somatic cells, which self-assemble and exhibit long-term hormone-responsive endocrine function. | Edmonds ME, Woodruff TK | Biofabrication | 32492667 | Biofabrication | 2020 Jul 9 |
| A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice. | Laronda MM, Rutz AL, Xiao S, Whelan KA, Duncan FE, Roth EW, Woodruff TK, Shah RN | Nature communications | 28509899 | Nat Commun | 2017 May 16 |
| Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators. | Moyle-Heyrman G, Schipma MJ, Dean M, Davis DA, Burdette JE | Journal of ovarian research | 26879975 | J Ovarian Res | 2016 Feb 15 |
| Good manufacturing practice requirements for the production of tissue vitrification and warming and recovery kits for clinical research. | Laronda MM, McKinnon KE, Ting AY, Le Fever AV, Zelinski MB, Woodruff TK | Journal of assisted reproduction and genetics | 27900615 | J Assist Reprod Genet | 2017 Feb |
| Engineered reproductive tissues. | Gargus ES, Rogers HB, McKinnon KE, Edmonds ME, Woodruff TK | Nature biomedical engineering | 32251392 | Nat Biomed Eng | 2020 Apr |
| Multidrug Resistance Protein 1 Deficiency Promotes Doxorubicin-Induced Ovarian Toxicity in Female Mice. | Wang Y, Liu M, Zhang J, Liu Y, Kopp M, Zheng W, Xiao S | Toxicological sciences : an official journal of the Society of Toxicology | 29462422 | Toxicol Sci | 2018 May 1 |
| Microphysiologic systems in female reproductive biology. | Young AN, Moyle-Heyrman G, Kim JJ, Burdette JE | Experimental biology and medicine (Maywood, N.J.) | 29065798 | Exp Biol Med (Maywood) | 2017 Nov |
| Doxorubicin Has Dose-Dependent Toxicity on Mouse Ovarian Follicle Development, Hormone Secretion, and Oocyte Maturation. | Xiao S, Zhang J, Liu M, Iwahata H, Rogers HB, Woodruff TK | Toxicological sciences : an official journal of the Society of Toxicology | 28329872 | Toxicol Sci | 2017 Jun 1 |
| Initiation of puberty in mice following decellularized ovary transplant. | Laronda MM, Jakus AE, Whelan KA, Wertheim JA, Shah RN, Woodruff TK | Biomaterials | 25736492 | Biomaterials | 2015 May |
| Distinct follicular and luteal transcriptional profiles in engineered human ectocervical tissue dependent on menstrual cycle phase. | McKinnon KE, Getsios S, Woodruff TK | Biology of reproduction | 32614039 | Biol Reprod | 2020 Aug 21 |
| Novel three dimensional human endocervix cultures respond to 28-day hormone treatment. | Arslan SY, Yu Y, Burdette JE, Pavone ME, Hope TJ, Woodruff TK, Kim JJ | Endocrinology | 25635622 | Endocrinology | 2015 Apr |
| Use of an organotypic mammalian in vitro follicle growth assay to facilitate female reproductive toxicity screening. | Xu Y, Duncan FE, Xu M, Woodruff TK | Reproduction, fertility, and development | 25689754 | Reprod Fertil Dev | 2015 Feb 18 |
| Endometriosis and ovarian cancer: links, risks, and challenges faced. | Pavone ME, Lyttle BM | International journal of women's health | 26170722 | Int J Womens Health | 2015 |
| A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. | Xiao S, Coppeta JR, Rogers HB, Isenberg BC, Zhu J, Olalekan SA, McKinnon KE, Dokic D, Rashedi AS, Haisenleder DJ, Malpani SS, Arnold-Murray CA, Chen K, Jiang M, Bai L, Nguyen CT, Zhang J, Laronda MM, Hope TJ, Maniar KP, Pavone ME, Avram MJ, Sefton EC, Getsios S, Burdette JE, Kim JJ, Borenstein JT, Woodruff TK | Nature communications | 28350383 | Nat Commun | 2017 Mar 28 |
| Approaching the in vitro clinical trial: engineering organs on chips. | Capulli AK, Tian K, Mehandru N, Bukhta A, Choudhury SF, Suchyta M, Parker KK | Lab on a chip | 24828385 | Lab Chip | 2014 Sep 7 |
| Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation. | Nesmith AP, Agarwal A, McCain ML, Parker KK | Lab on a chip | 25093641 | Lab Chip | 2014 Oct 21 |
| Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing. | Lind JU, Busbee TA, Valentine AD, Pasqualini FS, Yuan H, Yadid M, Park SJ, Kotikian A, Nesmith AP, Campbell PH, Vlassak JJ, Lewis JA, Parker KK | Nature materials | 27775708 | Nat Mater | 2017 Mar |
| Mechanotransduction and Metabolism in Cardiomyocyte Microdomains. | Pasqualini FS, Nesmith AP, Horton RE, Sheehy SP, Parker KK | BioMed research international | 28044126 | Biomed Res Int | 2016 |
| Traction force microscopy of engineered cardiac tissues. | Pasqualini FS, Agarwal A, O'Connor BB, Liu Q, Sheehy SP, Parker KK | PloS one | 29590169 | PLoS One | 2018 |
| Angiotensin II Induced Cardiac Dysfunction on a Chip. | Horton RE, Yadid M, McCain ML, Sheehy SP, Pasqualini FS, Park SJ, Cho A, Campbell P, Parker KK | PloS one | 26808388 | PLoS One | 2016 |
| Insights Into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia From Engineered Human Heart Tissue. | Park SJ, Zhang D, Qi Y, Li Y, Lee KY, Bezzerides VJ, Yang P, Xia S, Kim SL, Liu X, Lu F, Pasqualini FS, Campbell PH, Geva J, Roberts AE, Kleber AG, Abrams DJ, Pu WT, Parker KK | Circulation | 31311300 | Circulation | 2019 Jul 30 |
| Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues. | McCain ML, Agarwal A, Nesmith HW, Nesmith AP, Parker KK | Biomaterials | 24731714 | Biomaterials | 2014 Jul |
| Three-dimensional paper-based model for cardiac ischemia. | Mosadegh B, Dabiri BE, Lockett MR, Derda R, Campbell P, Parker KK, Whitesides GM | Advanced healthcare materials | 24574054 | Adv Healthc Mater | 2014 Jul |
| The role of mechanotransduction on vascular smooth muscle myocytes' [corrected] cytoskeleton and contractile function. | Ye GJ, Nesmith AP, Parker KK | Anatomical record (Hoboken, N.J. : 2007) | 25125187 | Anat Rec (Hoboken) | 2014 Sep |
| Phototactic guidance of a tissue-engineered soft-robotic ray. | Park SJ, Gazzola M, Park KS, Park S, Di Santo V, Blevins EL, Lind JU, Campbell PH, Dauth S, Capulli AK, Pasqualini FS, Ahn S, Cho A, Yuan H, Maoz BM, Vijaykumar R, Choi JW, Deisseroth K, Lauder GV, Mahadevan L, Parker KK | Science (New York, N.Y.) | 27387948 | Science | 2016 Jul 8 |
| Organ Chips: Quality Assurance Systems in Regenerative Medicine. | Pasqualini FS, Emmert MY, Parker KK, Hoerstrup SP | Clinical pharmacology and therapeutics | 27709615 | Clin Pharmacol Ther | 2017 Jan |
| Fibrous scaffolds for building hearts and heart parts. | Capulli AK, MacQueen LA, Sheehy SP, Parker KK | Advanced drug delivery reviews | 26656602 | Adv Drug Deliv Rev | 2016 Jan 15 |
| Continuous Formation of Ultrathin, Strong Collagen Sheets with Tunable Anisotropy and Compaction. | Malladi S, Miranda-Nieves D, Leng L, Grainger SJ, Tarabanis C, Nesmith AP, Kosaraju R, Haller CA, Parker KK, Chaikof EL, Günther A | ACS biomaterials science & engineering | 32685675 | ACS Biomater Sci Eng | 2020 Jul 13 |
| An autonomously swimming biohybrid fish designed with human cardiac biophysics. | Lee KY, Park SJ, Matthews DG, Kim SL, Marquez CA, Zimmerman JF, Ardoña HAM, Kleber AG, Lauder GV, Parker KK | Science (New York, N.Y.) | 35143298 | Science | 2022 Feb 11 |
| Myofibrils in Cardiomyocytes Tend to Assemble Along the Maximal Principle Stress Directions. | Yuan H, Marzban B, Kit Parker K | Journal of biomechanical engineering | 28857113 | J Biomech Eng | 2017 Dec 1 |
| Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence. | Garbern JC, Helman A, Sereda R, Sarikhani M, Ahmed A, Escalante GO, Ogurlu R, Kim SL, Zimmerman JF, Cho A, MacQueen L, Bezzerides VJ, Parker KK, Melton DA, Lee RT | Circulation | 31707831 | Circulation | 2020 Jan 28 |
| Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro. | Capulli AK, MacQueen LA, O'Connor BB, Dauth S, Parker KK | Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology | 27174867 | Cardiovasc Pathol | 2016 Jul-Aug |
| Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip. | McCain ML, Sheehy SP, Grosberg A, Goss JA, Parker KK | Proceedings of the National Academy of Sciences of the United States of America | 23716679 | Proc Natl Acad Sci U S A | 2013 Jun 11 |
| Quality metrics for stem cell-derived cardiac myocytes. | Sheehy SP, Pasqualini F, Grosberg A, Park SJ, Aratyn-Schaus Y, Parker KK | Stem cell reports | 24672752 | Stem Cell Reports | 2014 Mar 11 |
| Structural phenotyping of stem cell-derived cardiomyocytes. | Pasqualini FS, Sheehy SP, Agarwal A, Aratyn-Schaus Y, Parker KK | Stem cell reports | 25733020 | Stem Cell Reports | 2015 Mar 10 |
| A tissue-engineered scale model of the heart ventricle. | MacQueen LA, Sheehy SP, Chantre CO, Zimmerman JF, Pasqualini FS, Liu X, Goss JA, Campbell PH, Gonzalez GM, Park SJ, Capulli AK, Ferrier JP, Kosar TF, Mahadevan L, Pu WT, Parker KK | Nature biomedical engineering | 31015723 | Nat Biomed Eng | 2018 Dec |
| Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip. | Yadid M, Lind JU, Ardoña HAM, Sheehy SP, Dickinson LE, Eweje F, Bastings MMC, Pope B, O'Connor BB, Straubhaar JR, Budnik B, Kleber AG, Parker KK | Science translational medicine | 33055246 | Sci Transl Med | 2020 Oct 14 |
| Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening. | Lind JU, Yadid M, Perkins I, O'Connor BB, Eweje F, Chantre CO, Hemphill MA, Yuan H, Campbell PH, Vlassak JJ, Parker KK | Lab on a chip | 28976521 | Lab Chip | 2017 Oct 25 |
| Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications. | Nawroth JC, Scudder LL, Halvorson RT, Tresback J, Ferrier JP, Sheehy SP, Cho A, Kannan S, Sunyovszki I, Goss JA, Campbell PH, Parker KK | Biofabrication | 29337695 | Biofabrication | 2018 Jan 16 |
| JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement. | Capulli AK, Emmert MY, Pasqualini FS, Kehl D, Caliskan E, Lind JU, Sheehy SP, Park SJ, Ahn S, Weber B, Goss JA, Hoerstrup SP, Parker KK | Biomaterials | 28445803 | Biomaterials | 2017 Jul |
| Matrix elasticity regulates the optimal cardiac myocyte shape for contractility. | McCain ML, Yuan H, Pasqualini FS, Campbell PH, Parker KK | American journal of physiology. Heart and circulatory physiology | 24682394 | Am J Physiol Heart Circ Physiol | 2014 Jun 1 |
| Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. | Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, Wang DZ, Li K, Wang J, Wanders RJ, Kulik W, Vaz FM, Laflamme MA, Murry CE, Chien KR, Kelley RI, Church GM, Parker KK, Pu WT | Nature medicine | 24813252 | Nat Med | 2014 Jun |
| Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy. | Aratyn-Schaus Y, Pasqualini FS, Yuan H, McCain ML, Ye GJ, Sheehy SP, Campbell PH, Parker KK | The Journal of cell biology | 26858266 | J Cell Biol | 2016 Feb 15 |
| Recreating the heart's helical structure-function relationship with focused rotary jet spinning. | Chang H, Liu Q, Zimmerman JF, Lee KY, Jin Q, Peters MM, Rosnach M, Choi S, Kim SL, Ardoña HAM, MacQueen LA, Chantre CO, Motta SE, Cordoves EM, Parker KK | Science (New York, N.Y.) | 35857545 | Science | 2022 Jul 8 |
| Customizable biomaterials as tools for advanced anti-angiogenic drug discovery. | Nguyen EH, Murphy WL | Biomaterials | 30077137 | Biomaterials | 2018 Oct |
| Interspecies chimeric conditions affect the developmental rate of human pluripotent stem cells. | Brown J, Barry C, Schmitz MT, Argus C, Bolin JM, Schwartz MP, Van Aartsen A, Steill J, Swanson S, Stewart R, Thomson JA, Kendziorski C | PLoS computational biology | 33647016 | PLoS Comput Biol | 2021 Mar |
| Network inference with Granger causality ensembles on single-cell transcriptomics. | Deshpande A, Chu LF, Stewart R, Gitter A | Cell reports | 35139376 | Cell Rep | 2022 Feb 8 |
| Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and nontumorigenic human mesenchymal cell types. | Hansen TD, Koepsel JT, Le NN, Nguyen EH, Zorn S, Parlato M, Loveland SG, Schwartz MP, Murphy WL | Biomaterials science | 25386339 | Biomater Sci | 2014 May |
| Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays. | Nguyen EH, Zanotelli MR, Schwartz MP, Murphy WL | Biomaterials | 24332391 | Biomaterials | 2014 Feb |
| TimeMeter assesses temporal gene expression similarity and identifies differentially progressing genes. | Jiang P, Chamberlain CS, Vanderby R, Thomson JA, Stewart R | Nucleic acids research | 32123905 | Nucleic Acids Res | 2020 May 21 |
| Machine learning to predict developmental neurotoxicity with high-throughput data from 2D bio-engineered tissues. | Kuusisto F, Costa VS, Hou Z, Thomson J, Page D, Stewart R | Proceedings of the ... International Conference on Machine Learning and Applications. International Conference on Machine Learning and Applications | 32181450 | Proc Int Conf Mach Learn Appl | 2019 Dec |
| Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels. | Kaushik G, Gil DA, Torr E, Berge ES, Soref C, Uhl P, Fontana G, Antosiewicz-Bourget J, Edington C, Schwartz MP, Griffith LG, Thomson JA, Skala MC, Daly WT, Murphy WL | Advanced healthcare materials | 30565891 | Adv Healthc Mater | 2019 Jan |
| Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. | Hou Z, Zhang Y, Propson NE, Howden SE, Chu LF, Sontheimer EJ, Thomson JA | Proceedings of the National Academy of Sciences of the United States of America | 23940360 | Proc Natl Acad Sci U S A | 2013 Sep 24 |
| Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin. | Pellett S, Schwartz MP, Tepp WH, Josephson R, Scherf JM, Pier CL, Thomson JA, Murphy WL, Johnson EA | Scientific reports | 26411797 | Sci Rep | 2015 Sep 28 |
| Hydrogel arrays formed via differential wettability patterning enable combinatorial screening of stem cell behavior. | Le NNT, Zorn S, Schmitt SK, Gopalan P, Murphy WL | Acta biomaterialia | 26386315 | Acta Biomater | 2016 Apr 1 |
| Human pluripotent stem cell-derived neural constructs for predicting neural toxicity. | Schwartz MP, Hou Z, Propson NE, Zhang J, Engstrom CJ, Santos Costa V, Jiang P, Nguyen BK, Bolin JM, Daly W, Wang Y, Stewart R, Page CD, Murphy WL, Thomson JA | Proceedings of the National Academy of Sciences of the United States of America | 26392547 | Proc Natl Acad Sci U S A | 2015 Oct 6 |
| Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments. | Leng N, Chu LF, Barry C, Li Y, Choi J, Li X, Jiang P, Stewart RM, Thomson JA, Kendziorski C | Nature methods | 26301841 | Nat Methods | 2015 Oct |
| OEFinder: a user interface to identify and visualize ordering effects in single-cell RNA-seq data. | Leng N, Choi J, Chu LF, Thomson JA, Kendziorski C, Stewart R | Bioinformatics (Oxford, England) | 26743507 | Bioinformatics | 2016 May 1 |
| Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling. | Mina SG, Alaybeyoglu B, Murphy WL, Thomson JA, Stokes CL, Cirit M | Frontiers in big data | 33693346 | Front Big Data | 2019 |
| Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels. | Zanotelli MR, Ardalani H, Zhang J, Hou Z, Nguyen EH, Swanson S, Nguyen BK, Bolin J, Elwell A, Bischel LL, Xie AW, Stewart R, Beebe DJ, Thomson JA, Schwartz MP, Murphy WL | Acta biomaterialia | 26945632 | Acta Biomater | 2016 Apr 15 |
| A human pluripotent stem cell platform for assessing developmental neural toxicity screening. | Hou Z, Zhang J, Schwartz MP, Stewart R, Page CD, Murphy WL, Thomson JA | Stem cell research & therapy | 24565336 | Stem Cell Res Ther | 2013 |
| A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia. | Zhang J, McIntosh BE, Wang B, Brown ME, Probasco MD, Webster S, Duffin B, Zhou Y, Guo LW, Burlingham WJ, Kent C, Ferris M, Thomson JA | Stem cell reports | 31080110 | Stem Cell Reports | 2019 Jun 11 |
| Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments. | Bacher R, Leng N, Chu LF, Ni Z, Thomson JA, Kendziorski C, Stewart R | BMC bioinformatics | 30326833 | BMC Bioinformatics | 2018 Oct 16 |
| Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications. | Adamski M, Fontana G, Gershlak JR, Gaudette GR, Le HD, Murphy WL | Journal of visualized experiments : JoVE | 29912197 | J Vis Exp | 2018 May 31 |
| Functional characterization of human pluripotent stem cell-derived arterial endothelial cells. | Zhang J, Chu LF, Hou Z, Schwartz MP, Hacker T, Vickerman V, Swanson S, Leng N, Nguyen BK, Elwell A, Bolin J, Brown ME, Stewart R, Burlingham WJ, Murphy WL, Thomson JA | Proceedings of the National Academy of Sciences of the United States of America | 28696312 | Proc Natl Acad Sci U S A | 2017 Jul 25 |
| A Genome-wide Analysis of Human Pluripotent Stem Cell-Derived Endothelial Cells in 2D or 3D Culture. | Zhang J, Schwartz MP, Hou Z, Bai Y, Ardalani H, Swanson S, Steill J, Ruotti V, Elwell A, Nguyen BK, Bolin J, Stewart R, Thomson JA, Murphy WL | Stem cell reports | 28343999 | Stem Cell Reports | 2017 Apr 11 |
| Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques. | Barry C, Schmitz MT, Propson NE, Hou Z, Zhang J, Nguyen BK, Bolin JM, Jiang P, McIntosh BE, Probasco MD, Swanson S, Stewart R, Thomson JA, Schwartz MP, Murphy WL | Experimental biology and medicine (Maywood, N.J.) | 28599598 | Exp Biol Med (Maywood) | 2017 Nov |
| Species-specific developmental timing is maintained by pluripotent stem cells ex utero. | Barry C, Schmitz MT, Jiang P, Schwartz MP, Duffin BM, Swanson S, Bacher R, Bolin JM, Elwell AL, McIntosh BE, Stewart R, Thomson JA | Developmental biology | 28179190 | Dev Biol | 2017 Mar 15 |
| Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion. | Nguyen EH, Daly WT, Le NNT, Farnoodian M, Belair DG, Schwartz MP, Lebakken CS, Ananiev GE, Saghiri MA, Knudsen TB, Sheibani N, Murphy WL | Nature biomedical engineering | 29104816 | Nat Biomed Eng | 2017 |
| An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells. | Chu LF, Mamott D, Ni Z, Bacher R, Liu C, Swanson S, Kendziorski C, Stewart R, Thomson JA | Cell reports | 31461642 | Cell Rep | 2019 Aug 27 |
| Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics. | Barry C, Schmitz MT, Argus C, Bolin JM, Probasco MD, Leng N, Duffin BM, Steill J, Swanson S, McIntosh BE, Stewart R, Kendziorski C, Thomson JA, Bacher R | PLoS computational biology | 31815944 | PLoS Comput Biol | 2019 Dec |
| Human vascular tissue models formed from human induced pluripotent stem cell derived endothelial cells. | Belair DG, Whisler JA, Valdez J, Velazquez J, Molenda JA, Vickerman V, Lewis R, Daigh C, Hansen TD, Mann DA, Thomson JA, Griffith LG, Kamm RD, Schwartz MP, Murphy WL | Stem cell reviews and reports | 25190668 | Stem Cell Rev Rep | 2015 Jun |
| Biofunctionalized Plants as Diverse Biomaterials for Human Cell Culture. | Fontana G, Gershlak J, Adamski M, Lee JS, Matsumoto S, Le HD, Binder B, Wirth J, Gaudette G, Murphy WL | Advanced healthcare materials | 28319334 | Adv Healthc Mater | 2017 Apr |
| A cost-effective RNA sequencing protocol for large-scale gene expression studies. | Hou Z, Jiang P, Swanson SA, Elwell AL, Nguyen BK, Bolin JM, Stewart R, Thomson JA | Scientific reports | 25831155 | Sci Rep | 2015 Apr 1 |
| RNA-Seq of Human Neural Progenitor Cells Exposed to Lead (Pb) Reveals Transcriptome Dynamics, Splicing Alterations and Disease Risk Associations. | Jiang P, Hou Z, Bolin JM, Thomson JA, Stewart R | Toxicological sciences : an official journal of the Society of Toxicology | 28903495 | Toxicol Sci | 2017 Sep 1 |
| Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm. | Chu LF, Leng N, Zhang J, Hou Z, Mamott D, Vereide DT, Choi J, Kendziorski C, Stewart R, Thomson JA | Genome biology | 27534536 | Genome Biol | 2016 Aug 17 |
| A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. | Korthauer KD, Chu LF, Newton MA, Li Y, Thomson J, Stewart R, Kendziorski C | Genome biology | 27782827 | Genome Biol | 2016 Oct 25 |
| Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. | Jung Y, Ji H, Chen Z, Fai Chan H, Atchison L, Klitzman B, Truskey G, Leong KW | Scientific reports | 26456074 | Sci Rep | 2015 Oct 12 |
| Application of induced pluripotent stem cells to model smooth muscle cell function in vascular diseases. | Ji H, Kim HS, Kim HW, Leong KW | Current opinion in biomedical engineering | 29082353 | Curr Opin Biomed Eng | 2017 Mar |
| Biological and engineering design considerations for vascular tissue engineered blood vessels (TEBVs). | Fernandez CE, Achneck HE, Reichert WM, Truskey GA | Current opinion in chemical engineering | 24511460 | Curr Opin Chem Eng | 2014 Feb 1 |
| Physiology and metabolism of tissue-engineered skeletal muscle. | Cheng CS, Davis BN, Madden L, Bursac N, Truskey GA | Experimental biology and medicine (Maywood, N.J.) | 24912506 | Exp Biol Med (Maywood) | 2014 Sep |
| Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain. | Kabadi AM, Thakore PI, Vockley CM, Ousterout DG, Gibson TM, Guilak F, Reddy TE, Gersbach CA | ACS synthetic biology | 25494287 | ACS Synth Biol | 2015 Jun 19 |
| Human Vascular Microphysiological System for in vitro Drug Screening. | Fernandez CE, Yen RW, Perez SM, Bedell HW, Povsic TJ, Reichert WM, Truskey GA | Scientific reports | 26888719 | Sci Rep | 2016 Feb 18 |
| Tissue-engineered blood vessels as promising tools for testing drug toxicity. | Truskey GA, Fernandez CE | Expert opinion on drug metabolism & toxicology | 26028128 | Expert Opin Drug Metab Toxicol | 2015 Jul |
| Striated muscle function, regeneration, and repair. | Shadrin IY, Khodabukus A, Bursac N | Cellular and molecular life sciences : CMLS | 27271751 | Cell Mol Life Sci | 2016 Nov |
| Skin-inspired hydrogel-elastomer hybrids with robust interfaces and functional microstructures. | Yuk H, Zhang T, Parada GA, Liu X, Zhao X | Nature communications | 27345380 | Nat Commun | 2016 Jun 27 |
| Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions. | Chan HF, Zhang Y, Leong KW | Small (Weinheim an der Bergstrasse, Germany) | 27038291 | Small | 2016 May |
| Multifunctionality and control of the crumpling and unfolding of large-area graphene. | Zang J, Ryu S, Pugno N, Wang Q, Tu Q, Buehler MJ, Zhao X | Nature materials | 23334002 | Nat Mater | 2013 Apr |
| NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection. | Juul S, Obliosca JM, Liu C, Liu YL, Chen YA, Imphean DM, Knudsen BR, Ho YP, Leong KW, Yeh HC | Nanoscale | 25901841 | Nanoscale | 2015 May 14 |
| Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease. | Bursac N, Juhas M, Rando TA | Annual review of biomedical engineering | 26643021 | Annu Rev Biomed Eng | 2015 |
| Modeling the Effect of TNF-α upon Drug-Induced Toxicity in Human, Tissue-Engineered Myobundles. | Davis BNJ, Santoso JW, Walker MJ, Oliver CE, Cunningham MM, Boehm CA, Dawes D, Lasater SL, Huffman K, Kraus WE, Truskey GA | Annals of biomedical engineering | 30963383 | Ann Biomed Eng | 2019 Jul |
| Real-time observation of leukocyte-endothelium interactions in tissue-engineered blood vessel. | Chen Z, Tang M, Huang D, Jiang W, Li M, Ji H, Park J, Xu B, Atchison LJ, Truskey GA, Leong KW | Lab on a chip | 29927449 | Lab Chip | 2018 Jul 10 |
| Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscle. | Khodabukus A, Madden L, Prabhu NK, Koves TR, Jackman CP, Muoio DM, Bursac N | Biomaterials | 30180985 | Biomaterials | 2019 Apr |
| Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy. | Ousterout DG, Kabadi AM, Thakore PI, Majoros WH, Reddy TE, Gersbach CA | Nature communications | 25692716 | Nat Commun | 2015 Feb 18 |
| Nanograting structure promotes lamellipodia-based cell collective migration and wound healing. | Chen Z, Atchison L, Ji H, Leong KW | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 25570601 | Annu Int Conf IEEE Eng Med Biol Soc | 2014 |
| Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome. | Abutaleb NO, Atchison L, Choi L, Bedapudi A, Shores K, Gete Y, Cao K, Truskey GA | Scientific reports | 36977745 | Sci Rep | 2023 Mar 28 |
| Engineering skeletal muscle repair. | Juhas M, Bursac N | Current opinion in biotechnology | 23711735 | Curr Opin Biotechnol | 2013 Oct |
| Harnessing localized ridges for high-aspect-ratio hierarchical patterns with dynamic tunability and multifunctionality. | Cao C, Chan HF, Zang J, Leong KW, Zhao X | Advanced materials (Deerfield Beach, Fla.) | 24339233 | Adv Mater | 2014 Mar 19 |
| Bursting drops in solid dielectrics caused by high voltages. | Wang Q, Suo Z, Zhao X | Nature communications | 23093194 | Nat Commun | 2012 |
| Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems. | Hong S, Jung Y, Yen R, Chan HF, Leong KW, Truskey GA, Zhao X | Lab on a chip | 24310854 | Lab Chip | 2014 Feb 7 |
| Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing. | Truskey GA, Achneck HE, Bursac N, Chan H, Cheng CS, Fernandez C, Hong S, Jung Y, Koves T, Kraus WE, Leong K, Madden L, Reichert WM, Zhao X | Stem cell research & therapy | 24565225 | Stem Cell Res Ther | 2013 |
| Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases. | Ousterout DG, Kabadi AM, Thakore PI, Perez-Pinera P, Brown MT, Majoros WH, Reddy TE, Gersbach CA | Molecular therapy : the journal of the American Society of Gene Therapy | 25492562 | Mol Ther | 2015 Mar |
| Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis. | Chakraborty S, Ji H, Chen J, Gersbach CA, Leong KW | Scientific reports | 25492703 | Sci Rep | 2014 Dec 10 |
| Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors. | Thakore PI, Gersbach CA | Methods in molecular biology (Clifton, N.J.) | 26443215 | Methods Mol Biol | 2016 |
| Tough bonding of hydrogels to diverse non-porous surfaces. | Yuk H, Zhang T, Lin S, Parada GA, Zhao X | Nature materials | 26552058 | Nat Mater | 2016 Feb |
| Engineering human pluripotent stem cells into a functional skeletal muscle tissue. | Rao L, Qian Y, Khodabukus A, Ribar T, Bursac N | Nature communications | 29317646 | Nat Commun | 2018 Jan 9 |
| Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. | Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL | Scientific reports | 28176881 | Sci Rep | 2017 Feb 8 |
| RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. | Thakore PI, Kwon JB, Nelson CE, Rouse DC, Gemberling MP, Oliver ML, Gersbach CA | Nature communications | 29700298 | Nat Commun | 2018 Apr 26 |
| Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. | Cheng CS, Ran L, Bursac N, Kraus WE, Truskey GA | Tissue engineering. Part A | 26891613 | Tissue Eng Part A | 2016 Apr |
| Engineered skeletal muscles for disease modeling and drug discovery. | Wang J, Khodabukus A, Rao L, Vandusen K, Abutaleb N, Bursac N | Biomaterials | 31419653 | Biomaterials | 2019 Nov |
| Distilling complexity to advance cardiac tissue engineering. | Ogle BM, Bursac N, Domian I, Huang NF, Menasché P, Murry CE, Pruitt B, Radisic M, Wu JC, Wu SM, Zhang J, Zimmermann WH, Vunjak-Novakovic G | Science translational medicine | 27280684 | Sci Transl Med | 2016 Jun 8 |
| Advancing cardiovascular tissue engineering. | Truskey GA | F1000Research | 27303643 | F1000Res | 2016 |
| Tissue-Engineered Human Myobundle System as a Platform for Evaluation of Skeletal Muscle Injury Biomarkers. | Khodabukus A, Kaza A, Wang J, Prabhu N, Goldstein R, Vaidya VS, Bursac N | Toxicological sciences : an official journal of the Society of Toxicology | 32294208 | Toxicol Sci | 2020 Jul 1 |
| Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. | Zhang D, Shadrin IY, Lam J, Xian HQ, Snodgrass HR, Bursac N | Biomaterials | 23642535 | Biomaterials | 2013 Jul |
| On-demand hierarchical patterning with electric fields. | Wang Q, Robinson D, Zhao X | Applied physics letters | 25316923 | Appl Phys Lett | 2014 Jun 9 |
| Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs. | Madden L, Juhas M, Kraus WE, Truskey GA, Bursac N | eLife | 25575180 | Elife | 2015 Jan 9 |
| Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts. | Xing Q, Vogt C, Leong KW, Zhao F | Advanced functional materials | 25484849 | Adv Funct Mater | 2014 May 28 |
| Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair. | Jackman CP, Shadrin IY, Carlson AL, Bursac N | Current opinion in chemical engineering | 25599018 | Curr Opin Chem Eng | 2015 Feb |
| 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures. | Hong S, Sycks D, Chan HF, Lin S, Lopez GP, Guilak F, Leong KW, Zhao X | Advanced materials (Deerfield Beach, Fla.) | 26033288 | Adv Mater | 2015 Jul 15 |
| The Development of TALE Nucleases for Biotechnology. | Ousterout DG, Gersbach CA | Methods in molecular biology (Clifton, N.J.) | 26443211 | Methods Mol Biol | 2016 |
| Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles. | Rangarajan S, Madden L, Bursac N | Annals of biomedical engineering | 24366526 | Ann Biomed Eng | 2014 Jul |
| Materials innovation for co-delivery of diverse therapeutic cargos. | Godsey ME, Suryaprakash S, Leong KW | RSC advances | 24818000 | RSC Adv | 2013 Dec 21 |
| Multi-scale multi-mechanism design of tough hydrogels: building dissipation into stretchy networks. | Zhao X | Soft matter | 24834901 | Soft Matter | 2014 Feb 7 |
| Fringe instability in constrained soft elastic layers. | Lin S, Cohen T, Zhang T, Yuk H, Abeyaratne R, Zhao X | Soft matter | 27731462 | Soft Matter | 2016 Nov 4 |
| Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. | Christoforou N, Liau B, Chakraborty S, Chellapan M, Bursac N, Leong KW | PloS one | 23785459 | PLoS One | 2013 |
| Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers. | Fernandez CE, Obi-onuoha IC, Wallace CS, Satterwhite LL, Truskey GA, Reichert WM | Acta biomaterialia | 24140604 | Acta Biomater | 2014 Feb |
| Engineering mesenchymal stem cells for regenerative medicine and drug delivery. | Park JS, Suryaprakash S, Lao YH, Leong KW | Methods (San Diego, Calif.) | 25770356 | Methods | 2015 Aug |
| Integration of drug, protein, and gene delivery systems with regenerative medicine. | Lorden ER, Levinson HM, Leong KW | Drug delivery and translational research | 25787742 | Drug Deliv Transl Res | 2015 Apr |
| The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. | Kulangara K, Adler AF, Wang H, Chellappan M, Hammett E, Yasuda R, Leong KW | Biomaterials | 24709523 | Biomaterials | 2014 Jul |
| Nanotopography alters nuclear protein expression, proliferation and differentiation of human mesenchymal stem/stromal cells. | Kulangara K, Yang J, Chellappan M, Yang Y, Leong KW | PloS one | 25521962 | PLoS One | 2014 |
| Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies? | Chan HF, Ma S, Leong KW | Regenerative biomaterials | 27047674 | Regen Biomater | 2016 Jun |
| Oxygen consumption in human, tissue-engineered myobundles during basal and electrical stimulation conditions. | Davis BN, Yen R, Prasad V, Truskey GA | APL bioengineering | 31149650 | APL Bioeng | 2019 Jun |
| iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome. | Atchison L, Abutaleb NO, Snyder-Mounts E, Gete Y, Ladha A, Ribar T, Cao K, Truskey GA | Stem cell reports | 32032552 | Stem Cell Reports | 2020 Feb 11 |
| Glucose Uptake and Insulin Response in Tissue-engineered Human Skeletal Muscle. | Kondash ME, Ananthakumar A, Khodabukus A, Bursac N, Truskey GA | Tissue engineering and regenerative medicine | 32200516 | Tissue Eng Regen Med | 2020 Dec |
| Modeling statin myopathy in a human skeletal muscle microphysiological system. | Ananthakumar A, Liu Y, Fernandez CE, Truskey GA, Voora D | PloS one | 33237943 | PLoS One | 2020 |
| A system to monitor statin-induced myopathy in individual engineered skeletal muscle myobundles. | Zhang X, Hong S, Yen R, Kondash M, Fernandez CE, Truskey GA | Lab on a chip | 30112530 | Lab Chip | 2018 Sep 11 |
| Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide. | Wang HX, Song Z, Lao YH, Xu X, Gong J, Cheng D, Chakraborty S, Park JS, Li M, Huang D, Yin L, Cheng J, Leong KW | Proceedings of the National Academy of Sciences of the United States of America | 29686087 | Proc Natl Acad Sci U S A | 2018 May 8 |
| A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells. | Atchison L, Zhang H, Cao K, Truskey GA | Scientific reports | 28811655 | Sci Rep | 2017 Aug 15 |
| Human, Tissue-Engineered, Skeletal Muscle Myobundles to Measure Oxygen Uptake and Assess Mitochondrial Toxicity. | Davis BN, Santoso JW, Walker MJ, Cheng CS, Koves TR, Kraus WE, Truskey GA | Tissue engineering. Part C, Methods | 28338413 | Tissue Eng Part C Methods | 2017 Apr |
| In Vitro Tissue-Engineered Skeletal Muscle Models for Studying Muscle Physiology and Disease. | Khodabukus A, Prabhu N, Wang J, Bursac N | Advanced healthcare materials | 29696831 | Adv Healthc Mater | 2018 Aug |
| Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. | Cheng CS, El-Abd Y, Bui K, Hyun YE, Hughes RH, Kraus WE, Truskey GA | American journal of physiology. Cell physiology | 24336652 | Am J Physiol Cell Physiol | 2014 Feb 15 |
| A CRISPR/Cas9-based system for reprogramming cell lineage specification. | Chakraborty S, Ji H, Kabadi AM, Gersbach CA, Christoforou N, Leong KW | Stem cell reports | 25448066 | Stem Cell Reports | 2014 Dec 9 |
| MicroRNA delivery for regenerative medicine. | Peng B, Chen Y, Leong KW | Advanced drug delivery reviews | 26024978 | Adv Drug Deliv Rev | 2015 Jul 1 |
| Enabling functional genomics with genome engineering. | Hilton IB, Gersbach CA | Genome research | 26430154 | Genome Res | 2015 Oct |
| Transdifferentiation of human endothelial progenitors into smooth muscle cells. | Ji H, Atchison L, Chen Z, Chakraborty S, Jung Y, Truskey GA, Christoforou N, Leong KW | Biomaterials | 26874281 | Biomaterials | 2016 Apr |
| High-density lipoprotein subclass measurements improve mortality risk prediction, discrimination and reclassification in a cardiac catheterization cohort. | McGarrah RW, Craig DM, Haynes C, Dowdy ZE, Shah SH, Kraus WE | Atherosclerosis | 26803432 | Atherosclerosis | 2016 Mar |
| Stretchable Hydrogel Electronics and Devices. | Lin S, Yuk H, Zhang T, Parada GA, Koo H, Yu C, Zhao X | Advanced materials (Deerfield Beach, Fla.) | 26639322 | Adv Mater | 2016 Jun |
| A versatile platform for surface modification of microfluidic droplets. | Li M, Jiang W, Chen Z, Suryaprakash S, Lv S, Tang Z, Chen X, Leong KW | Lab on a chip | 28154857 | Lab Chip | 2017 Feb 14 |
| Dynamic culture yields engineered myocardium with near-adult functional output. | Jackman CP, Carlson AL, Bursac N | Biomaterials | 27723557 | Biomaterials | 2016 Dec |
| Development of a microphysiological model of human kidney proximal tubule function. | Weber EJ, Chapron A, Chapron BD, Voellinger JL, Lidberg KA, Yeung CK, Wang Z, Yamaura Y, Hailey DW, Neumann T, Shen DD, Thummel KE, Muczynski KA, Himmelfarb J, Kelly EJ | Kidney international | 27521113 | Kidney Int | 2016 Sep |
| Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function. | Chang SY, Weber EJ, Ness KV, Eaton DL, Kelly EJ | Clinical pharmacology and therapeutics | 27448090 | Clin Pharmacol Ther | 2016 Nov |
| Human Organ-Specific Endothelial Cell Heterogeneity. | Marcu R, Choi YJ, Xue J, Fortin CL, Wang Y, Nagao RJ, Xu J, MacDonald JW, Bammler TK, Murry CE, Muczynski K, Stevens KR, Himmelfarb J, Schwartz SM, Zheng Y | iScience | 30240741 | iScience | 2018 Jun 29 |
| Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection. | Foulke-Abel J, Yu H, Sunuwar L, Lin R, Fleckenstein JM, Kaper JB, Donowitz M | Gut microbes | 32378997 | Gut Microbes | 2020 Nov 9 |
| Predicting tubular reabsorption with a human kidney proximal tubule tissue-on-a-chip and physiologically-based modeling. | Sakolish C, Chen Z, Dalaijamts C, Mitra K, Liu Y, Fulton T, Wade TL, Kelly EJ, Rusyn I, Chiu WA | Toxicology in vitro : an international journal published in association with BIBRA | 31857146 | Toxicol In Vitro | 2020 Mar |
| Microphysiological system modeling of ochratoxin A-associated nephrotoxicity. | Imaoka T, Yang J, Wang L, McDonald MG, Afsharinejad Z, Bammler TK, Van Ness K, Yeung CK, Rettie AE, Himmelfarb J, Kelly EJ | Toxicology | 32905824 | Toxicology | 2020 Nov |
| Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease. | Lidberg KA, Annalora AJ, Jozic M, Elson DJ, Wang L, Bammler TK, Ramm S, Monteiro MB, Himmelfarb J, Marcus CB, Iversen PL, Kelly EJ | Scientific reports | 33633318 | Sci Rep | 2021 Feb 25 |
| Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. | Foulke-Abel J, In J, Yin J, Zachos NC, Kovbasnjuk O, Estes MK, de Jonge H, Donowitz M | Gastroenterology | 26677983 | Gastroenterology | 2016 Mar |
| Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease. | Cruz NM, Song X, Czerniecki SM, Gulieva RE, Churchill AJ, Kim YK, Winston K, Tran LM, Diaz MA, Fu H, Finn LS, Pei Y, Himmelfarb J, Freedman BS | Nature materials | 28967916 | Nat Mater | 2017 Nov |
| Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis. | Campanholle G, Ligresti G, Gharib SA, Duffield JS | American journal of physiology. Cell physiology | 23325411 | Am J Physiol Cell Physiol | 2013 Apr 1 |
| Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. | Hung C, Linn G, Chow YH, Kobayashi A, Mittelsteadt K, Altemeier WA, Gharib SA, Schnapp LM, Duffield JS | American journal of respiratory and critical care medicine | 23924232 | Am J Respir Crit Care Med | 2013 Oct 1 |
| Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics. | Prasad B, Johnson K, Billington S, Lee C, Chung GW, Brown CD, Kelly EJ, Himmelfarb J, Unadkat JD | Drug metabolism and disposition: the biological fate of chemicals | 27621205 | Drug Metab Dispos | 2016 Dec |
| Development of a Kidney Microphysiological System Hardware Platform for Microgravity Studies. | Yeung C, Jones-Isaac K, Lindberg K, Yang J, Bain J, Ruiz M, Koenig G, Koenig P, Countryman S, Himmelfarb J, Kelly E | Research square | 38196654 | Res Sq | 2023 Dec 22 |
| Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system. | Lidberg KA, Jones-Isaac K, Yang J, Bain J, Wang L, MacDonald JW, Bammler TK, Calamia J, Thummel KE, Yeung CK, Countryman S, Koenig P, Himmelfarb J, Kelly EJ | NPJ microgravity | 38982119 | NPJ Microgravity | 2024 Jul 9 |
| A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro. | Adler M, Ramm S, Hafner M, Muhlich JL, Gottwald EM, Weber E, Jaklic A, Ajay AK, Svoboda D, Auerbach S, Kelly EJ, Himmelfarb J, Vaidya VS | Journal of the American Society of Nephrology : JASN | 26260164 | J Am Soc Nephrol | 2016 Apr |
| Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system. | Kelly EJ, Wang Z, Voellinger JL, Yeung CK, Shen DD, Thummel KE, Zheng Y, Ligresti G, Eaton DL, Muczynski KA, Duffield JS, Neumann T, Tourovskaia A, Fauver M, Kramer G, Asp E, Himmelfarb J | Stem cell research & therapy | 24564863 | Stem Cell Res Ther | 2013 |
| TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease. | Gomez IG, Roach AM, Nakagawa N, Amatucci A, Johnson BG, Dunn K, Kelly MC, Karaca G, Zheng TS, Szak S, Peppiatt-Wildman CM, Burkly LC, Duffield JS | Journal of the American Society of Nephrology : JASN | 27026366 | J Am Soc Nephrol | 2016 Dec |
| RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis. | Craciun FL, Bijol V, Ajay AK, Rao P, Kumar RK, Hutchinson J, Hofmann O, Joshi N, Luyendyk JP, Kusebauch U, Moss CL, Srivastava A, Himmelfarb J, Waikar SS, Moritz RL, Vaidya VS | Journal of the American Society of Nephrology : JASN | 26449608 | J Am Soc Nephrol | 2016 Jun |
| Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci. | Sieber KB, Batorsky A, Siebenthall K, Hudkins KL, Vierstra JD, Sullivan S, Sur A, McNulty M, Sandstrom R, Reynolds A, Bates D, Diegel M, Dunn D, Nelson J, Buckley M, Kaul R, Sampson MG, Himmelfarb J, Alpers CE, Waterworth D, Akilesh S | Journal of the American Society of Nephrology : JASN | 30760496 | J Am Soc Nephrol | 2019 Mar |
| High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping. | Czerniecki SM, Cruz NM, Harder JL, Menon R, Annis J, Otto EA, Gulieva RE, Islas LV, Kim YK, Tran LM, Martins TJ, Pippin JW, Fu H, Kretzler M, Shankland SJ, Himmelfarb J, Moon RT, Paragas N, Freedman BS | Cell stem cell | 29779890 | Cell Stem Cell | 2018 Jun 1 |
| A Novel Three-Dimensional Human Peritubular Microvascular System. | Ligresti G, Nagao RJ, Xue J, Choi YJ, Xu J, Ren S, Aburatani T, Anderson SK, MacDonald JW, Bammler TK, Schwartz SM, Muczynski KA, Duffield JS, Himmelfarb J, Zheng Y | Journal of the American Society of Nephrology : JASN | 26657868 | J Am Soc Nephrol | 2016 Aug |
| A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation. | Monteiro MB, Ramm S, Chandrasekaran V, Boswell SA, Weber EJ, Lidberg KA, Kelly EJ, Vaidya VS | Journal of the American Society of Nephrology : JASN | 30361326 | J Am Soc Nephrol | 2018 Dec |
| Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity. | Weber EJ, Lidberg KA, Wang L, Bammler TK, MacDonald JW, Li MJ, Redhair M, Atkins WM, Tran C, Hines KM, Herron J, Xu L, Monteiro MB, Ramm S, Vaidya V, Vaara M, Vaara T, Himmelfarb J, Kelly EJ | JCI insight | 30568031 | JCI Insight | 2018 Dec 20 |
| Kidney microphysiological models for nephrotoxicity assessment. | Mahadeo A, Yeung CK, Himmelfarb J, Kelly EJ | Current opinion in toxicology | 35495549 | Curr Opin Toxicol | 2022 Jun |
| Development of a kidney microphysiological system hardware platform for microgravity studies. | Jones-Isaac KA, Lidberg KA, Yeung CK, Yang J, Bain J, Ruiz M, Koenig G, Koenig P, Countryman S, Himmelfarb J, Kelly EJ | NPJ microgravity | 38734683 | NPJ Microgravity | 2024 May 11 |
| The inexorable rise of AKI: can we bend the growth curve? | Siew ED, Himmelfarb J | Journal of the American Society of Nephrology : JASN | 23243210 | J Am Soc Nephrol | 2013 Jan |
| Changes in macrophage phenotype as the immune response evolves. | Lichtnekert J, Kawakami T, Parks WC, Duffield JS | Current opinion in pharmacology | 23747023 | Curr Opin Pharmacol | 2013 Aug |
| Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport. | Yeung CK, Shen DD, Thummel KE, Himmelfarb J | Kidney international | 24132209 | Kidney Int | 2014 Mar |
| EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury. | Kida Y, Ieronimakis N, Schrimpf C, Reyes M, Duffield JS | Journal of the American Society of Nephrology : JASN | 23492730 | J Am Soc Nephrol | 2013 Mar |
| Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia. | Cruz NM, Reddy R, McFaline-Figueroa JL, Tran C, Fu H, Freedman BS | Nature biomedical engineering | 35478224 | Nat Biomed Eng | 2022 Apr |
| Cellular and molecular mechanisms in kidney fibrosis. | Duffield JS | The Journal of clinical investigation | 24892703 | J Clin Invest | 2014 Jun |
| Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS. | Kawakami T, Gomez IG, Ren S, Hudkins K, Roach A, Alpers CE, Shankland SJ, D'Agati VD, Duffield JS | Journal of the American Society of Nephrology : JASN | 25406339 | J Am Soc Nephrol | 2015 May |
| Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel. | Hiraki HL, Nagao RJ, Himmelfarb J, Zheng Y | Journal of visualized experiments : JoVE | 30371659 | J Vis Exp | 2018 Oct 13 |
| Engineered 3D Microvascular Networks for the Study of Ultrasound-Microbubble-Mediated Drug Delivery. | Juang EK, De Cock I, Keravnou C, Gallagher MK, Keller SB, Zheng Y, Averkiou M | Langmuir : the ACS journal of surfaces and colloids | 30540481 | Langmuir | 2019 Aug 6 |
| A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis. | Miller CP, Tsuchida C, Zheng Y, Himmelfarb J, Akilesh S | Neoplasia (New York, N.Y.) | 29747161 | Neoplasia | 2018 Jun |
| Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment. | Kotha S, Sun S, Adams A, Hayes B, Phong KT, Nagao R, Reems JA, Gao D, Torok-Storb B, López JA, Zheng Y | PloS one | 29617409 | PLoS One | 2018 |
| Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury. | Chen YT, Chang YT, Pan SY, Chou YH, Chang FC, Yeh PY, Liu YH, Chiang WC, Chen YM, Wu KD, Tsai TJ, Duffield JS, Lin SL | Journal of the American Society of Nephrology : JASN | 24854266 | J Am Soc Nephrol | 2014 Dec |
| Concise Review: Current and Emerging Biomarkers of Nephrotoxicity. | Weber EJ, Himmelfarb J, Kelly EJ | Current opinion in toxicology | 29057384 | Curr Opin Toxicol | 2017 Jun |
| Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology. | Watson DE, Hunziker R, Wikswo JP | Experimental biology and medicine (Maywood, N.J.) | 29065799 | Exp Biol Med (Maywood) | 2017 Oct |
| Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease. | Nakagawa N, Barron L, Gomez IG, Johnson BG, Roach AM, Kameoka S, Jack RM, Lupher ML Jr, Gharib SA, Duffield JS | JCI insight | 27942582 | JCI Insight | 2016 Dec 8 |
| Impact of microgravity on a three-dimensional microphysiologic culture of the human kidney proximal tubule epithelium: cell response to serum and vitamin D. | Kelly E, Lindberg K, Jones-Isaac K, Yang J, Bain J, Wang L, MacDonald J, Bammler T, Calamia J, Thummel K, Yeung C, Countryman S, Koenig P, Himmelfarb J | Research square | 38196580 | Res Sq | 2023 Dec 21 |
| Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease. | Li SR, Gulieva RE, Helms L, Cruz NM, Vincent T, Fu H, Himmelfarb J, Freedman BS | Nature communications | 36564419 | Nat Commun | 2022 Dec 23 |
| Interferon-γ induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease. | Juliar BA, Stanaway IB, Sano F, Fu H, Smith KD, Akilesh S, Scales SJ, El Saghir J, Bhatraju PK, Liu E, Yang J, Lin J, Eddy S, Kretzler M, Zheng Y, Himmelfarb J, Harder JL, Freedman BS | Cell reports | 38838223 | Cell Rep | 2024 Jun 25 |
| Pericytes in kidney fibrosis. | Ren S, Duffield JS | Current opinion in nephrology and hypertension | 23722183 | Curr Opin Nephrol Hypertens | 2013 Jul |
| Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions. | Kawakami T, Lichtnekert J, Thompson LJ, Karna P, Bouabe H, Hohl TM, Heinecke JW, Ziegler SF, Nelson PJ, Duffield JS | Journal of immunology (Baltimore, Md. : 1950) | 23956422 | J Immunol | 2013 Sep 15 |
| Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity. | Chang SY, Voellinger JL, Van Ness KP, Chapron B, Shaffer RM, Neumann T, White CC, Kavanagh TJ, Kelly EJ, Eaton DL | Toxicology in vitro : an international journal published in association with BIBRA | 28089783 | Toxicol In Vitro | 2017 Apr |
| Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes. | Bhatraju PK, Cohen M, Nagao RJ, Morrell ED, Kosamo S, Chai XY, Nance R, Dmyterko V, Delaney J, Christie JD, Liu KD, Mikacenic C, Gharib SA, Liles WC, Zheng Y, Christiani DC, Himmelfarb J, Wurfel MM | BMC nephrology | 32680471 | BMC Nephrol | 2020 Jul 17 |
| Tissue-engineered microenvironment systems for modeling human vasculature. | Tourovskaia A, Fauver M, Kramer G, Simonson S, Neumann T | Experimental biology and medicine (Maywood, N.J.) | 25030480 | Exp Biol Med (Maywood) | 2014 Sep |
| Translational Assessment of Drug-Induced Proximal Tubule Injury Using a Kidney Microphysiological System. | Maass C, Sorensen NB, Himmelfarb J, Kelly EJ, Stokes CL, Cirit M | CPT: pharmacometrics & systems pharmacology | 30869201 | CPT Pharmacometrics Syst Pharmacol | 2019 May |
| A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro. | Ramm S, Todorov P, Chandrasekaran V, Dohlman A, Monteiro MB, Pavkovic M, Muhlich J, Shankaran H, Chen WW, Mettetal JT, Vaidya VS | Toxicological sciences : an official journal of the Society of Toxicology | 30649541 | Toxicol Sci | 2019 May 1 |
| Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. | Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL | JCI insight | 29202460 | JCI Insight | 2017 Nov 16 |
| Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip. | Sakolish C, Weber EJ, Kelly EJ, Himmelfarb J, Mouneimne R, Grimm FA, House JS, Wade T, Han A, Chiu WA, Rusyn I | Scientific reports | 30291268 | Sci Rep | 2018 Oct 5 |
| Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics. | Bajaj P, Chowdhury SK, Yucha R, Kelly EJ, Xiao G | Drug metabolism and disposition: the biological fate of chemicals | 30076203 | Drug Metab Dispos | 2018 Nov |
| Reconstructing the Human Renal Vascular-Tubular Unit In Vitro. | Rayner SG, Phong KT, Xue J, Lih D, Shankland SJ, Kelly EJ, Himmelfarb J, Zheng Y | Advanced healthcare materials | 30379416 | Adv Healthc Mater | 2018 Dec |
| Circadian hormone control in a human-on-a-chip: In vitro biology's ignored component? | Cyr KJ, Avaldi OM, Wikswo JP | Experimental biology and medicine (Maywood, N.J.) | 29065796 | Exp Biol Med (Maywood) | 2017 Nov |
| Microphysiological Systems to Assess Nonclinical Toxicity. | Van Ness KP, Chang SY, Weber EJ, Zumpano D, Eaton DL, Kelly EJ | Current protocols in toxicology | 28777442 | Curr Protoc Toxicol | 2017 Aug 4 |
| Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins. | Cil O, Phuan PW, Gillespie AM, Lee S, Tradtrantip L, Yin J, Tse M, Zachos NC, Lin R, Donowitz M, Verkman AS | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 27871064 | FASEB J | 2017 Feb |
| Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways. | Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS | The Journal of clinical investigation | 25415439 | J Clin Invest | 2015 Jan |
| The FOXD1 lineage of kidney perivascular cells and myofibroblasts: functions and responses to injury. | Gomez IG, Duffield JS | Kidney international supplements | 26312147 | Kidney Int Suppl (2011) | 2014 Nov |
| Cyclosporine Induces Fenestra-Associated Injury in Human Renal Microvessels In Vitro. | Nagao RJ, Marcu R, Shin YJ, Lih D, Xue J, Arang N, Wei L, Akilesh S, Kaushansky A, Himmelfarb J, Zheng Y | ACS biomaterials science & engineering | 34927415 | ACS Biomater Sci Eng | 2022 Jan 10 |
| Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism. | Yamaura Y, Chapron BD, Wang Z, Himmelfarb J, Thummel KE | Drug metabolism and disposition: the biological fate of chemicals | 26700954 | Drug Metab Dispos | 2016 Mar |
| Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence. | Nagao RJ, Xu J, Luo P, Xue J, Wang Y, Kotha S, Zeng W, Fu X, Himmelfarb J, Zheng Y | Tissue engineering. Part A | 27481445 | Tissue Eng Part A | 2016 Oct |
| Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury. | Leaf IA, Nakagawa S, Johnson BG, Cha JJ, Mittelsteadt K, Guckian KM, Gomez IG, Altemeier WA, Duffield JS | The Journal of clinical investigation | 27869651 | J Clin Invest | 2017 Jan 3 |
| Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation. | Cil O, Phuan PW, Son JH, Zhu JS, Ku CK, Tabib NA, Teuthorn AP, Ferrera L, Zachos NC, Lin R, Galietta LJV, Donowitz M, Kurth MJ, Verkman AS | Translational research : the journal of laboratory and clinical medicine | 27815136 | Transl Res | 2017 Apr |
| A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX. | Li X, George SM, Vernetti L, Gough AH, Taylor DL | Lab on a chip | 30063238 | Lab Chip | 2018 Aug 21 |
| Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS). | Sakolish C, Reese CE, Luo YS, Valdiviezo A, Schurdak ME, Gough A, Taylor DL, Chiu WA, Vernetti LA, Rusyn I | Toxicology | 33307106 | Toxicology | 2021 Jan 30 |
| Prediction of hepatic drug clearance with a human microfluidic four-cell liver acinus microphysiology system. | Sakolish C, Luo YS, Valdiviezo A, Vernetti LA, Rusyn I, Chiu WA | Toxicology | 34543702 | Toxicology | 2021 Nov |
| In vitro platforms for evaluating liver toxicity. | Bale SS, Vernetti L, Senutovitch N, Jindal R, Hegde M, Gough A, McCarty WJ, Bakan A, Bhushan A, Shun TY, Golberg I, DeBiasio R, Usta BO, Taylor DL, Yarmush ML | Experimental biology and medicine (Maywood, N.J.) | 24764241 | Exp Biol Med (Maywood) | 2014 Sep |
| SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. | Tobita T, Guzman-Lepe J, Takeishi K, Nakao T, Wang Y, Meng F, Deng CX, Collin de l'Hortet A, Soto-Gutierrez A | PloS one | 26890260 | PLoS One | 2016 |
| Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies. | Usta OB, McCarty WJ, Bale S, Hegde M, Jindal R, Bhushan A, Golberg I, Yarmush ML | Technology | 26167518 | Technology (Singap World Sci) | 2015 Mar |
| A Microfabricated Platform for Generating Physiologically-Relevant Hepatocyte Zonation. | McCarty WJ, Usta OB, Yarmush ML | Scientific reports | 27240736 | Sci Rep | 2016 May 31 |
| A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine. | Stern AM, Schurdak ME, Bahar I, Berg JM, Taylor DL | Journal of biomolecular screening | 26962875 | J Biomol Screen | 2016 Jul |
| Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems. | Soto-Gutierrez A, Gough A, Vernetti LA, Taylor DL, Monga SP | Experimental biology and medicine (Maywood, N.J.) | 28467181 | Exp Biol Med (Maywood) | 2017 Oct |
| Development and validation of a microfluidic immunoassay capable of multiplexing parallel samples in microliter volumes. | Ghodbane M, Stucky EC, Maguire TJ, Schloss RS, Shreiber DI, Zahn JD, Yarmush ML | Lab on a chip | 26130452 | Lab Chip | 2015 Aug 7 |
| Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. | Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevila C, Stärkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R | Nature communications | 31311938 | Nat Commun | 2019 Jul 16 |
| Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems. | Lee-Montiel FT, George SM, Gough AH, Sharma AD, Wu J, DeBiasio R, Vernetti LA, Taylor DL | Experimental biology and medicine (Maywood, N.J.) | 28409533 | Exp Biol Med (Maywood) | 2017 Oct |
| iPSC-Derived Neurons from Patients with POLG Mutations Exhibit Decreased Mitochondrial Content and Dendrite Simplification. | Verma M, Francis L, Lizama BN, Callio J, Fricklas G, Wang KZQ, Kaufman BA, D'Aiuto L, Stolz DB, Watkins SC, Nimgaonkar VL, Soto-Gutierrez A, Goldstein A, Chu CT | The American journal of pathology | 36414085 | Am J Pathol | 2023 Feb |
| Fluorescent protein biosensors applied to microphysiological systems. | Senutovitch N, Vernetti L, Boltz R, DeBiasio R, Gough A, Taylor DL | Experimental biology and medicine (Maywood, N.J.) | 25990438 | Exp Biol Med (Maywood) | 2015 Jun |
| Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery. | Gough AH, Chen N, Shun TY, Lezon TR, Boltz RC, Reese CE, Wagner J, Vernetti LA, Grandis JR, Lee AV, Stern AM, Schurdak ME, Taylor DL | PloS one | 25036749 | PLoS One | 2014 |
| Long-term coculture strategies for primary hepatocytes and liver sinusoidal endothelial cells. | Bale SS, Golberg I, Jindal R, McCarty WJ, Luitje M, Hegde M, Bhushan A, Usta OB, Yarmush ML | Tissue engineering. Part C, Methods | 25233394 | Tissue Eng Part C Methods | 2015 Apr |
| Dynamic interplay of flow and collagen stabilizes primary hepatocytes culture in a microfluidic platform. | Hegde M, Jindal R, Bhushan A, Bale SS, McCarty WJ, Golberg I, Usta OB, Yarmush ML | Lab on a chip | 24770663 | Lab Chip | 2014 Jun 21 |
| Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization. | McCarty WJ, Prodanov L, Bale SS, Bhushan A, Jindal R, Yarmush ML, Usta OB | Journal of visualized experiments : JoVE | 26485274 | J Vis Exp | 2015 Sep 29 |
| Liver metastases: Microenvironments and ex-vivo models. | Clark AM, Ma B, Taylor DL, Griffith L, Wells A | Experimental biology and medicine (Maywood, N.J.) | 27390264 | Exp Biol Med (Maywood) | 2016 Sep |
| Human organoid cultures: transformative new tools for human virus studies. | Ramani S, Crawford SE, Blutt SE, Estes MK | Current opinion in virology | 29656244 | Curr Opin Virol | 2018 Apr |
| Human mini-guts: new insights into intestinal physiology and host-pathogen interactions. | In JG, Foulke-Abel J, Estes MK, Zachos NC, Kovbasnjuk O, Donowitz M | Nature reviews. Gastroenterology & hepatology | 27677718 | Nat Rev Gastroenterol Hepatol | 2016 Nov |
| Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation. | Blutt SE, Crawford SE, Bomidi C, Zeng XL, Broughman JR, Robertson M, Coarfa C, Tessier MEM, Savidge T, Hollinger FB, Curley SA, Donowitz M, Estes MK | American journal of physiology. Gastrointestinal and liver physiology | 34288725 | Am J Physiol Gastrointest Liver Physiol | 2021 Sep 1 |
| Applications of the microphysiology systems database for experimental ADME-Tox and disease models. | Schurdak M, Vernetti L, Bergenthal L, Wolter QK, Shun TY, Karcher S, Taylor DL, Gough A | Lab on a chip | 32211684 | Lab Chip | 2020 Apr 14 |
| A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®. | Bircsak KM, DeBiasio R, Miedel M, Alsebahi A, Reddinger R, Saleh A, Shun T, Vernetti LA, Gough A | Toxicology | 33359578 | Toxicology | 2021 Feb 28 |
| Human Hepatocellular response in Cholestatic Liver Diseases. | Ortiz K, Cetin Z, Sun Y, Hu Z, Kurihara T, Tafaleng EN, Florentino RM, Ostrowska A, Soto-Gutierrez A, Faccioli LAP | Organogenesis | 37598346 | Organogenesis | 2023 Dec 31 |
| Liver-Regenerative Transplantation: Regrow and Reset. | Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Handa K, Matsubara K, Fukumitsu K, Dorko K, Presnell SC, Yagi H, Soto-Gutierrez A | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons | 26699680 | Am J Transplant | 2016 Jun |
| A novel ultrathin collagen nanolayer assembly for 3-D microtissue engineering: Layer-by-layer collagen deposition for long-term stable microfluidic hepatocyte culture. | McCarty WJ, Usta OB, Luitje M, Bale SS, Bhushan A, Hegde M, Golberg I, Jindal R, Yarmush ML | Technology | 24932459 | Technology (Singap World Sci) | 2014 Mar |
| Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes. | Jia S, Miedel MT, Ngo M, Hessenius R, Chen N, Wang P, Bahreini A, Li Z, Ding Z, Shun TY, Zuckerman DM, Taylor DL, Puhalla SL, Lee AV, Oesterreich S, Stern AM | Oncology | 29306943 | Oncology | 2018 |
| Biotunable acoustic node assembly of organoids. | Chen P, Güven S, Usta OB, Yarmush ML, Demirci U | Advanced healthcare materials | 26149464 | Adv Healthc Mater | 2015 Sep 16 |
| Biologically Relevant Heterogeneity: Metrics and Practical Insights. | Gough A, Stern AM, Maier J, Lezon T, Shun TY, Chennubhotla C, Schurdak ME, Haney SA, Taylor DL | SLAS discovery : advancing life sciences R & D | 28231035 | SLAS Discov | 2017 Mar |
| Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response. | Bale SS, Geerts S, Jindal R, Yarmush ML | Scientific reports | 27142224 | Sci Rep | 2016 May 4 |
| Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans. | Bhushan A, Senutovitch N, Bale SS, McCarty WJ, Hegde M, Jindal R, Golberg I, Berk Usta O, Yarmush ML, Vernetti L, Gough A, Bakan A, Shun TY, DeBiasio R, Lansing Taylor D | Stem cell research & therapy | 24565476 | Stem Cell Res Ther | 2013 |
| The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models. | Gough A, Vernetti L, Bergenthal L, Shun TY, Taylor DL | Applied in vitro toxicology | 28781990 | Appl In Vitro Toxicol | 2016 Jun 1 |
| Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy. | Vernetti LA, Vogt A, Gough A, Taylor DL | Clinics in liver disease | 27842772 | Clin Liver Dis | 2017 Feb |
| Development of a low-volume, highly sensitive microimmunoassay using computational fluid dynamics-driven multiobjective optimization. | Ghodbane M, Kulesa A, Yu HH, Maguire TJ, Schloss RR, Ramachandran R, Zahn JD, Yarmush ML | Microfluidics and nanofluidics | 25691853 | Microfluid Nanofluidics | 2015 Feb |
| Long-term maintenance of a microfluidic 3D human liver sinusoid. | Prodanov L, Jindal R, Bale SS, Hegde M, McCarty WJ, Golberg I, Bhushan A, Yarmush ML, Usta OB | Biotechnology and bioengineering | 26152452 | Biotechnol Bioeng | 2016 Jan |
| A human liver microphysiology platform for investigating physiology, drug safety, and disease models. | Vernetti LA, Senutovitch N, Boltz R, DeBiasio R, Shun TY, Gough A, Taylor DL | Experimental biology and medicine (Maywood, N.J.) | 26202373 | Exp Biol Med (Maywood) | 2016 Jan |
| A novel low-volume two-chamber microfabricated platform for evaluating drug metabolism and toxicity. | Bale SS, Sridharan GV, Golberg I, Prodanov L, McCarty WJ, Usta OB, Jindal R, Yarmush ML | Technology | 26925437 | Technology (Singap World Sci) | 2015 Dec |
| Evaluation of Human Hepatocyte Drug Metabolism Carrying High-Risk or Protection-Associated Liver Disease Genetic Variants. | Faccioli LAP, Cetin Z, Kocas-Kilicarslan ZN, Ortiz K, Sun Y, Hu Z, Kurihara T, Tafaleng EN, Florentino RM, Wang Z, Xia M, Miedel MT, Taylor DL, Behari J, Ostrowska A, Constantine R, Li A, Soto-Gutierrez A | International journal of molecular sciences | 37686209 | Int J Mol Sci | 2023 Aug 29 |
| Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling. | Beckwitt CH, Shiraha K, Wells A | PloS one | 29763460 | PLoS One | 2018 |
| High resolution stereolithography fabrication of perfusable scaffolds to enable long-term meso-scale hepatic culture for disease modeling. | Sphabmixay P, Raredon MSB, Wang AJ, Lee H, Hammond PT, Fang NX, Griffith LG | Biofabrication | 34479229 | Biofabrication | 2021 Sep 21 |
| Bioreactor technologies to support liver function in vitro. | Ebrahimkhani MR, Neiman JA, Raredon MS, Hughes DJ, Griffith LG | Advanced drug delivery reviews | 24607703 | Adv Drug Deliv Rev | 2014 Apr |
| A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties. | Clark AM, Wheeler SE, Young CL, Stockdale L, Shepard Neiman J, Zhao W, Stolz DB, Venkataramanan R, Lauffenburger D, Griffith L, Wells A | Lab on a chip | 27910972 | Lab Chip | 2016 Dec 20 |
| Expression of E-cadherin and specific CXCR3 isoforms impact each other in prostate cancer. | Ma B, Khazali A, Shao H, Jiang Y, Wells A | Cell communication and signaling : CCS | 31831069 | Cell Commun Signal | 2019 Dec 12 |
| The dormancy dilemma: quiescence versus balanced proliferation. | Wells A, Griffith L, Wells JZ, Taylor DP | Cancer research | 23794703 | Cancer Res | 2013 Jul 1 |
| Engineering Modular 3D Liver Culture Microenvironments In Vitro to Parse the Interplay between Biophysical and Biochemical Microenvironment Cues on Hepatic Phenotypes. | Wang AJ, Allen A, Sofman M, Sphabmixay P, Yildiz E, Griffith LG | Advanced nanobiomed research | 35872804 | Adv Nanobiomed Res | 2022 Jan |
| Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion. | Grahovac J, Wells A | Laboratory investigation; a journal of technical methods and pathology | 24247562 | Lab Invest | 2014 Jan |
| Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor. | Sarkar U, Rivera-Burgos D, Large EM, Hughes DJ, Ravindra KC, Dyer RL, Ebrahimkhani MR, Wishnok JS, Griffith LG, Tannenbaum SR | Drug metabolism and disposition: the biological fate of chemicals | 25926431 | Drug Metab Dispos | 2015 Jul |
| All-human microphysical model of metastasis therapy. | Wheeler SE, Borenstein JT, Clark AM, Ebrahimkhani MR, Fox IJ, Griffith L, Inman W, Lauffenburger D, Nguyen T, Pillai VC, Prantil-Baun R, Stolz DB, Taylor D, Ulrich T, Venkataramanan R, Wells A, Young C | Stem cell research & therapy | 24565274 | Stem Cell Res Ther | 2013 |
| Modeling boundary conditions for balanced proliferation in metastatic latency. | Taylor DP, Wells JZ, Savol A, Chennubhotla C, Wells A | Clinical cancer research : an official journal of the American Association for Cancer Research | 23329811 | Clin Cancer Res | 2013 Mar 1 |
| Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. | Warita K, Warita T, Beckwitt CH, Schurdak ME, Vazquez A, Wells A, Oltvai ZN | Scientific reports | 25534349 | Sci Rep | 2014 Dec 23 |
| CXCR3 in carcinoma progression. | Ma B, Khazali A, Wells A | Histology and histopathology | 25663474 | Histol Histopathol | 2015 Jul |
| Tenascin-C Signaling in melanoma. | Shao H, Kirkwood JM, Wells A | Cell adhesion & migration | 25482624 | Cell Adh Migr | 2015 |
| The mitogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase (ERK) are involved in hepatocyte-mediated phenotypic switching in prostate cancer cells. | Ma B, Wells A | The Journal of biological chemistry | 24619413 | J Biol Chem | 2014 Apr 18 |
| Approaches to in vitro tissue regeneration with application for human disease modeling and drug development. | Ebrahimkhani MR, Young CL, Lauffenburger DA, Griffith LG, Borenstein JT | Drug discovery today | 24793141 | Drug Discov Today | 2014 Jun |
| Liver 'organ on a chip'. | Beckwitt CH, Clark AM, Wheeler S, Taylor DL, Stolz DB, Griffith L, Wells A | Experimental cell research | 29291400 | Exp Cell Res | 2018 Feb 1 |
| Physiome-on-a-Chip: The Challenge of "Scaling" in Design, Operation, and Translation of Microphysiological Systems. | Stokes CL, Cirit M, Lauffenburger DA | CPT: pharmacometrics & systems pharmacology | 26535154 | CPT Pharmacometrics Syst Pharmacol | 2015 Oct |
| Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS). | Maass C, Stokes CL, Griffith LG, Cirit M | Integrative biology : quantitative biosciences from nano to macro | 28267162 | Integr Biol (Camb) | 2017 Apr 18 |
| Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform. | Long TJ, Cosgrove PA, Dunn RT 2nd, Stolz DB, Hamadeh H, Afshari C, McBride H, Griffith LG | Drug metabolism and disposition: the biological fate of chemicals | 27621203 | Drug Metab Dispos | 2016 Dec |
| Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration. | Yu J, Cilfone NA, Large EM, Sarkar U, Wishnok JS, Tannenbaum SR, Hughes DJ, Lauffenburger DA, Griffith LG, Stokes CL, Cirit M | CPT: pharmacometrics & systems pharmacology | 26535159 | CPT Pharmacometrics Syst Pharmacol | 2015 Oct |
| Liver protects metastatic prostate cancer from induced death by activating E-cadherin signaling. | Ma B, Wheeler SE, Clark AM, Whaley DL, Yang M, Wells A | Hepatology (Baltimore, Md.) | 27482645 | Hepatology | 2016 Nov |
| Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies. | Tsamandouras N, Chen WLK, Edington CD, Stokes CL, Griffith LG, Cirit M | The AAPS journal | 28752430 | AAPS J | 2017 Sep |
| Modeling the Complexity of the Metastatic Niche Ex Vivo. | Clark AM | Methods in molecular biology (Clifton, N.J.) | 33340364 | Methods Mol Biol | 2021 |
| Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies. | Maass C, Dallas M, LaBarge ME, Shockley M, Valdez J, Geishecker E, Stokes CL, Griffith LG, Cirit M | Scientific reports | 29789564 | Sci Rep | 2018 May 22 |
| Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells. | Dioufa N, Clark AM, Ma B, Beckwitt CH, Wells A | Molecular cancer | 29137633 | Mol Cancer | 2017 Nov 14 |
| Biomarker identification for statin sensitivity of cancer cell lines. | Raghu VK, Beckwitt CH, Warita K, Wells A, Benos PV, Oltvai ZN | Biochemical and biophysical research communications | 29146185 | Biochem Biophys Res Commun | 2018 Jan 1 |
| Covalent Modification of Synthetic Hydrogels with Bioactive Proteins via Sortase-Mediated Ligation. | Cambria E, Renggli K, Ahrens CC, Cook CD, Kroll C, Krueger AT, Imperiali B, Griffith LG | Biomacromolecules | 26098148 | Biomacromolecules | 2015 Aug 10 |
| Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition. | Taylor DP, Clark A, Wheeler S, Wells A | Breast cancer research and treatment | 24610032 | Breast Cancer Res Treat | 2014 Apr |
| A microphysiological system model of therapy for liver micrometastases. | Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan R, Griffith LG, Wells A | Experimental biology and medicine (Maywood, N.J.) | 24821820 | Exp Biol Med (Maywood) | 2014 Sep |
| Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model. | Rivera-Burgos D, Sarkar U, Lever AR, Avram MJ, Coppeta JR, Wishnok JS, Borenstein JT, Tannenbaum SR | Drug metabolism and disposition: the biological fate of chemicals | 26586376 | Drug Metab Dispos | 2016 Feb |
| MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock. | Kader M, Alaoui-El-Azher M, Vorhauer J, Kode BB, Wells JZ, Stolz D, Michalopoulos G, Wells A, Scott M, Ismail N | PLoS pathogens | 29049365 | PLoS Pathog | 2017 Oct |
| IP-10 (CXCL10) Can Trigger Emergence of Dormant Breast Cancer Cells in a Metastatic Liver Microenvironment. | Clark AM, Heusey HL, Griffith LG, Lauffenburger DA, Wells A | Frontiers in oncology | 34123844 | Front Oncol | 2021 |
| Engineering liver. | Griffith LG, Wells A, Stolz DB | Hepatology (Baltimore, Md.) | 24668880 | Hepatology | 2014 Oct |
| Photopatterning of hydrogel scaffolds coupled to filter materials using stereolithography for perfused 3D culture of hepatocytes. | Neiman JA, Raman R, Chan V, Rhoads MG, Raredon MS, Velazquez JJ, Dyer RL, Bashir R, Hammond PT, Griffith LG | Biotechnology and bioengineering | 25384798 | Biotechnol Bioeng | 2015 Apr |
| Adult Stem Cell Functioning in the Tumor Micro-Environment. | Jiang Y, Wells A, Sylakowski K, Clark AM, Ma B | International journal of molecular sciences | 31130595 | Int J Mol Sci | 2019 May 25 |
| Integrated gut/liver microphysiological systems elucidates inflammatory inter-tissue crosstalk. | Chen WLK, Edington C, Suter E, Yu J, Velazquez JJ, Velazquez JG, Shockley M, Large EM, Venkataramanan R, Hughes DJ, Stokes CL, Trumper DL, Carrier RL, Cirit M, Griffith LG, Lauffenburger DA | Biotechnology and bioengineering | 28667746 | Biotechnol Bioeng | 2017 Nov |
| A Perspective on Therapeutic Pan-Resistance in Metastatic Cancer. | Korentzelos D, Clark AM, Wells A | International journal of molecular sciences | 33022920 | Int J Mol Sci | 2020 Oct 3 |
| Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy. | Khazali AS, Clark AM, Wells A | British journal of cancer | 29169181 | Br J Cancer | 2018 Feb 20 |
| A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures. | Clark AM, Kumar MP, Wheeler SE, Young CL, Venkataramanan R, Stolz DB, Griffith LG, Lauffenburger DA, Wells A | Molecular & cellular proteomics : MCP | 29353230 | Mol Cell Proteomics | 2018 Apr |
| On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks. | Valdez J, Cook CD, Ahrens CC, Wang AJ, Brown A, Kumar M, Stockdale L, Rothenberg D, Renggli K, Gordon E, Lauffenburger D, White F, Griffith L | Biomaterials | 28371736 | Biomaterials | 2017 Jun |
| The pan-therapeutic resistance of disseminated tumor cells: Role of phenotypic plasticity and the metastatic microenvironment. | Ma B, Wells A, Clark AM | Seminars in cancer biology | 31376430 | Semin Cancer Biol | 2020 Feb |
| Integrative microphysiological tissue systems of cancer metastasis to the liver. | Clark AM, Allbritton NL, Wells A | Seminars in cancer biology | 32580025 | Semin Cancer Biol | 2021 Jun |
| Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells. | Furukawa M, Wheeler S, Clark AM, Wells A | PloS one | 25635394 | PLoS One | 2015 |
| Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system. | Wheeler SE, Clark AM, Taylor DP, Young CL, Pillai VC, Stolz DB, Venkataramanan R, Lauffenburger D, Griffith L, Wells A | British journal of cancer | 25314052 | Br J Cancer | 2014 Dec 9 |
| Use of ChemoFx® for Identification of Effective Treatments in Epithelial Ovarian Cancer. | Richard S, Wells A, Connor J, Price F | PLoS currents | 26213638 | PLoS Curr | 2015 Jul 13 |
| Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells. | Yang M, Ma B, Shao H, Clark AM, Wells A | BMC cancer | 27387344 | BMC Cancer | 2016 Jul 7 |
| Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System. | Tsamandouras N, Kostrzewski T, Stokes CL, Griffith LG, Hughes DJ, Cirit M | The Journal of pharmacology and experimental therapeutics | 27760784 | J Pharmacol Exp Ther | 2017 Jan |
| A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms. | Khazali AS, Clark AM, Wells A | Stem cell reviews and reports | 28425064 | Stem Cell Rev Rep | 2017 Jun |
| Patterned polymer matrix promotes stemness and cell-cell interaction of adult stem cells. | Hofmeister LH, Costa L, Balikov DA, Crowder SW, Terekhov A, Sung HJ, Hofmeister WH | Journal of biological engineering | 26464581 | J Biol Eng | 2015 |
| Cerebral Waste Accumulation and Glymphatic Clearance as Mechanisms of Human Neurological Diseases. | Dadas A, Washington J, Janigro D | Journal of neurology & neuromedicine | 30506062 | J Neurol Neuromedicine | 2016 |
| Oligoproline-derived nanocarrier for dual stimuli-responsive gene delivery. | Gupta MK , Lee SH , Crowder SW , Wang X , Hofmeister LH , Nelson CE , Bellan LM , Duvall CL , Sung HJ | Journal of materials chemistry. B | 32262835 | J Mater Chem B | 2015 Sep 28 |
| Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits. | Puvenna V, Brennan C, Shaw G, Yang C, Marchi N, Bazarian JJ, Merchant-Borna K, Janigro D | PloS one | 24806476 | PLoS One | 2014 |
| Poly(ε-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells. | Crowder SW, Liang Y, Rath R, Park AM, Maltais S, Pintauro PN, Hofmeister W, Lim CC, Wang X, Sung HJ | Nanomedicine (London, England) | 23530764 | Nanomedicine (Lond) | 2013 Nov |
| New immunological approaches in treating and diagnosing CNS diseases. | Guo K, Janigro D | Pharmaceutical patent analyst | 24237062 | Pharm Pat Anal | 2013 May |
| Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels. | Zachman AL, Wang X, Tucker-Schwartz JM, Fitzpatrick ST, Lee SH, Guelcher SA, Skala MC, Sung HJ | Biomaterials | 25154665 | Biomaterials | 2014 Dec |
| Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems. | Marasco CC, Goodwin CR, Winder DG, Schramm-Sapyta NL, McLean JA, Wikswo JP | Experimental biology and medicine (Maywood, N.J.) | 24903164 | Exp Biol Med (Maywood) | 2014 Nov |
| Bond-specific dissociation following excitation energy transfer for distance constraint determination in the gas phase. | Hendricks NG, Lareau NM, Stow SM, McLean JA, Julian RR | Journal of the American Chemical Society | 25174489 | J Am Chem Soc | 2014 Sep 24 |
| ROS-cleavable proline oligomer crosslinking of polycaprolactone for pro-angiogenic host response. | Lee SH, Boire TC, Lee JB, Gupta MK, Zachman AL, Rath R, Sung HJ | Journal of materials chemistry. B | 25343029 | J Mater Chem B | 2014 Nov 7 |
| Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study. | Ghosh C, Hossain M, Spriggs A, Ghosh A, Grant GA, Marchi N, Perucca E, Janigro D | Epilepsia | 25656284 | Epilepsia | 2015 Mar |
| Ion mobility-mass spectrometry: time-dispersive instrumentation. | May JC, McLean JA | Analytical chemistry | 25526595 | Anal Chem | 2015 Feb 3 |
| S100B blood levels and childhood trauma in adolescent inpatients. | Falcone T, Janigro D, Lovell R, Simon B, Brown CA, Herrera M, Myint AM, Anand A | Journal of psychiatric research | 25669696 | J Psychiatr Res | 2015 Mar |
| Evaluation of Collision Cross Section Calibrants for Structural Analysis of Lipids by Traveling Wave Ion Mobility-Mass Spectrometry. | Hines KM, May JC, McLean JA, Xu L | Analytical chemistry | 27321977 | Anal Chem | 2016 Jul 19 |
| Detection of brain-directed autoantibodies in the serum of non-small cell lung cancer patients. | Banjara M, Ghosh C, Dadas A, Mazzone P, Janigro D | PloS one | 28746384 | PLoS One | 2017 |
| A new dynamic in vitro modular capillaries-venules modular system: cerebrovascular physiology in a box. | Cucullo L, Hossain M, Tierney W, Janigro D | BMC neuroscience | 23388041 | BMC Neurosci | 2013 Feb 6 |
| Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain depends on disease status. | Chun YW, Voyles DE, Rath R, Hofmeister LH, Boire TC, Wilcox H, Lee JH, Bellan LM, Hong CC, Sung HJ | Journal of biomechanics | 26476764 | J Biomech | 2015 Nov 5 |
| MALDI-TOF/TOF CID Study of Poly(1,4-dihydroxybenzene terephthalate) Fragmentation Reactions. | Gies AP, Stow SM, McLean JA, Hercules DM | Polymer | 26195848 | Polymer (Guildf) | 2015 May 1 |
| A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches. | Janigro D, Iffland PH 2nd, Marchi N, Granata T | Epilepsia | 24001067 | Epilepsia | 2013 Sep |
| The relevance and potential roles of microphysiological systems in biology and medicine. | Wikswo JP | Experimental biology and medicine (Maywood, N.J.) | 25187571 | Exp Biol Med (Maywood) | 2014 Sep |
| Note: A single-chamber tool for plasma activation and surface functionalization in microfabrication. | Bowman AJ, Scherrer JR, Reiserer RS | The Review of scientific instruments | 26133881 | Rev Sci Instrum | 2015 Jun |
| Blood-brain barrier, bulk flow, and interstitial clearance in epilepsy. | Marchi N, Banjara M, Janigro D | Journal of neuroscience methods | 26093166 | J Neurosci Methods | 2016 Feb 15 |
| Systems-Wide High-Dimensional Data Acquisition and Informatics Using Structural Mass Spectrometry Strategies. | Sherrod SD, McLean JA | Clinical chemistry | 26453699 | Clin Chem | 2016 Jan |
| Broadscale resolving power performance of a high precision uniform field ion mobility-mass spectrometer. | May JC, Dodds JN, Kurulugama RT, Stafford GC, Fjeldsted JC, McLean JA | The Analyst | 26191544 | Analyst | 2015 Oct 21 |
| Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes. | Chun YW, Balikov DA, Feaster TK, Williams CH, Sheng CC, Lee JB, Boire TC, Neely MD, Bellan LM, Ess KC, Bowman AB, Sung HJ, Hong CC | Biomaterials | 26204225 | Biomaterials | 2015 Oct |
| Real-Time Monitoring of Cellular Bioenergetics with a Multianalyte Screen-Printed Electrode. | McKenzie JR, Cognata AC, Davis AN, Wikswo JP, Cliffel DE | Analytical chemistry | 26125545 | Anal Chem | 2015 Aug 4 |
| Engineering challenges for instrumenting and controlling integrated organ-on-chip systems. | Wikswo JP, Block FE 3rd, Cliffel DE, Goodwin CR, Marasco CC, Markov DA, McLean DL, McLean JA, McKenzie JR, Reiserer RS, Samson PC, Schaffer DK, Seale KT, Sherrod SD | IEEE transactions on bio-medical engineering | 23380852 | IEEE Trans Biomed Eng | 2013 Mar |
| Cancer Stem Cells under Hypoxia as a Chemoresistance Factor in Breast and Brain. | Crowder SW, Balikov DA, Hwang YS, Sung HJ | Current pathobiology reports | 24587979 | Curr Pathobiol Rep | 2014 Mar |
| Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. | Kumar KK, Goodwin CR, Uhouse MA, Bornhorst J, Schwerdtle T, Aschner M, McLean JA, Bowman AB | Metallomics : integrated biometal science | 25599126 | Metallomics | 2015 Feb |
| Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures. | Lizama-Manibusan BN, Klein S, McKenzie JR, Cliffel DE, McLaughlin B | ACS chemical neuroscience | 27504748 | ACS Chem Neurosci | 2016 Sep 21 |
| Ultrathin Polymer Membranes with Patterned, Micrometric Pores for Organs-on-Chips. | Pensabene V, Costa L, Terekhov AY, Gnecco JS, Wikswo JP, Hofmeister WH | ACS applied materials & interfaces | 27513606 | ACS Appl Mater Interfaces | 2016 Aug 31 |
| Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge. | May JC, McLean JA | Annual review of analytical chemistry (Palo Alto, Calif.) | 27306312 | Annu Rev Anal Chem (Palo Alto Calif) | 2016 Jun 12 |
| Novel behavior of the chromatographic separation of linear and cyclic polymers. | Montenegro-Burke JR, Bennett JM, McLean JA, Hercules DM | Analytical and bioanalytical chemistry | 26637218 | Anal Bioanal Chem | 2016 Jan |
| Untargeted Metabolomics Strategies-Challenges and Emerging Directions. | Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA | Journal of the American Society for Mass Spectrometry | 27624161 | J Am Soc Mass Spectrom | 2016 Dec |
| Cationic Nanocylinders Promote Angiogenic Activities of Endothelial Cells. | Lee JB, Balikov DA, Yang JW, Kim KS, Park HK, Kim JK, Kwon IK, Bellan LM, Sung HJ | Polymers | 29034114 | Polymers (Basel) | 2016 Jan |
| Transporters in drug-refractory epilepsy: clinical significance. | Marchi N, Gonzalez-Martinez J, Nguyen MT, Granata T, Janigro D | Clinical pharmacology and therapeutics | 20019694 | Clin Pharmacol Ther | 2010 Jan |
| Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier. | Janigro D | Epilepsia | 22612806 | Epilepsia | 2012 Jun |
| Expression and functional relevance of UGT1A4 in a cohort of human drug-resistant epileptic brains. | Ghosh C, Hossain M, Puvenna V, Martinez-Gonzalez J, Alexopolous A, Janigro D, Marchi N | Epilepsia | 23865846 | Epilepsia | 2013 Sep |
| Three-dimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells. | Crowder SW, Prasai D, Rath R, Balikov DA, Bae H, Bolotin KI, Sung HJ | Nanoscale | 23592029 | Nanoscale | 2013 May 21 |
| In Situ Crosslinkable Gelatin Hydrogels for Vasculogenic Induction and Delivery of Mesenchymal Stem Cells. | Lee SH, Lee Y, Chun YW, Crowder SW, Young PP, Park KD, Sung HJ | Advanced functional materials | 26327818 | Adv Funct Mater | 2014 Nov 19 |
| Pathophysiological implications of neurovascular P450 in brain disorders. | Ghosh C, Hossain M, Solanki J, Dadas A, Marchi N, Janigro D | Drug discovery today | 27312874 | Drug Discov Today | 2016 Oct |
| Lipid profiling of polarized human monocyte-derived macrophages. | Montenegro-Burke JR, Sutton JA, Rogers LM, Milne GL, McLean JA, Aronoff DM | Prostaglandins & other lipid mediators | 27871801 | Prostaglandins Other Lipid Mediat | 2016 Dec |
| S100B and S100B autoantibody as biomarkers for early detection of brain metastases in lung cancer. | Choi H, Puvenna V, Brennan C, Mahmoud S, Wang XF, Phillips M, Janigro D, Mazzone P | Translational lung cancer research | 27652205 | Transl Lung Cancer Res | 2016 Aug |
| Improving the clinical management of traumatic brain injury through the pharmacokinetic modeling of peripheral blood biomarkers. | Dadas A, Washington J, Marchi N, Janigro D | Fluids and barriers of the CNS | 27903281 | Fluids Barriers CNS | 2016 Nov 30 |
| Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer. | May JC, Goodwin CR, Lareau NM, Leaptrot KL, Morris CB, Kurulugama RT, Mordehai A, Klein C, Barry W, Darland E, Overney G, Imatani K, Stafford GC, Fjeldsted JC, McLean JA | Analytical chemistry | 24446877 | Anal Chem | 2014 Feb 18 |
| Current progress in Reactive Oxygen Species (ROS)-Responsive materials for biomedical applications. | Lee SH, Gupta MK, Bang JB, Bae H, Sung HJ | Advanced healthcare materials | 25136729 | Adv Healthc Mater | 2013 |
| Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia. | Brown JA, Sherrod SD, Goodwin CR, Brewer B, Yang L, Garbett KA, Li D, McLean JA, Wikswo JP, Mirnics K | Journal of neuroinflammation | 25374324 | J Neuroinflammation | 2014 Nov 6 |
| Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases. | Hines KM, Ballard BR, Marshall DR, McLean JA | Molecular bioSystems | 25212505 | Mol Biosyst | 2014 Nov |
| Wavelet-based peak detection and a new charge inference procedure for MS/MS implemented in ProteoWizard's msConvert. | French WR, Zimmerman LJ, Schilling B, Gibson BW, Miller CA, Townsend RR, Sherrod SD, Goodwin CR, McLean JA, Tabb DL | Journal of proteome research | 25411686 | J Proteome Res | 2015 Feb 6 |
| Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease. | Wilkerson I, Laban J, Mitchell JM, Sheibani N, Alcendor DJ | Journal of neuroinflammation | 25573478 | J Neuroinflammation | 2015 Jan 9 |
| Biology coming full circle: joining the whole and the parts. | Wikswo JP, Porter AP | Experimental biology and medicine (Maywood, N.J.) | 25583953 | Exp Biol Med (Maywood) | 2015 Jan |
| Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. | Evans JC, Hines KM, Forsythe JG, Erdogan B, Shi M, Hill S, Rose KL, McLean JA, Webb DJ | Journal of proteome research | 24874604 | J Proteome Res | 2014 Jul 3 |
| What non-neuronal mechanisms should be studied to understand epileptic seizures? | Janigro D, Walker MC | Advances in experimental medicine and biology | 25012382 | Adv Exp Med Biol | 2014 |
| Ion mobility-mass spectrometry strategies for untargeted systems, synthetic, and chemical biology. | May JC, Goodwin CR, McLean JA | Current opinion in biotechnology | 25462629 | Curr Opin Biotechnol | 2015 Feb |
| Mesangial cells, specialized renal pericytes and cytomegalovirus infectivity: Implications for HCMV pathology in the glomerular vascular unit and post-transplant renal disease. | Popik W, Correa H, Khatua A, Aronoff DM, Alcendor DJ | Journal of translational science | 29977613 | J Transl Sci | 2019 Feb |
| Real-time cellular exometabolome analysis with a microfluidic-mass spectrometry platform. | Marasco CC, Enders JR, Seale KT, McLean JA, Wikswo JP | PloS one | 25723555 | PLoS One | 2015 |
| Structural Characterization of Methylenedianiline Regioisomers by Ion Mobility-Mass Spectrometry, Tandem Mass Spectrometry, and Computational Strategies. 2. Electrospray Spectra of 3-Ring and 4-Ring Isomers. | Stow SM, Onifer TM, Forsythe JG, Nefzger H, Kwiecien NW, May JC, McLean JA, Hercules DM | Analytical chemistry | 25971782 | Anal Chem | 2015 Jun 16 |
| Polymeric stent materials dysregulate macrophage and endothelial cell functions: implications for coronary artery stent. | Wang X, Zachman AL, Chun YW, Shen FW, Hwang YS, Sung HJ | International journal of cardiology | 24820736 | Int J Cardiol | 2014 Jul 1 |
| Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression. | Boussadia B, Ghosh C, Plaud C, Pascussi JM, de Bock F, Rousset MC, Janigro D, Marchi N | Neuroscience | 25280786 | Neuroscience | 2014 Dec 5 |
| Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease. | Roach T, Alcendor DJ | Journal of neuroinflammation | 28253931 | J Neuroinflammation | 2017 Mar 3 |
| Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor. | Brown JA, Pensabene V, Markov DA, Allwardt V, Neely MD, Shi M, Britt CM, Hoilett OS, Yang Q, Brewer BM, Samson PC, McCawley LJ, May JM, Webb DJ, Li D, Bowman AB, Reiserer RS, Wikswo JP | Biomicrofluidics | 26576206 | Biomicrofluidics | 2015 Sep |
| Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit. | Brown JA, Codreanu SG, Shi M, Sherrod SD, Markov DA, Neely MD, Britt CM, Hoilett OS, Reiserer RS, Samson PC, McCawley LJ, Webb DJ, Bowman AB, McLean JA, Wikswo JP | Journal of neuroinflammation | 27955696 | J Neuroinflammation | 2016 Dec 12 |
| A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models. | Singh D, Deosarkar SP, Cadogan E, Flemington V, Bray A, Zhang J, Reiserer RS, Schaffer DK, Gerken GB, Britt CM, Werner EM, Gibbons FD, Kostrzewski T, Chambers CE, Davies EJ, Montoya AR, Fok JHL, Hughes D, Fabre K, Wagoner MP, Wikswo JP, Scott CW | PLoS biology | 35617197 | PLoS Biol | 2022 May |
| Elucidation of adhesion-dependent spontaneous apoptosis in macrophages using phase separated PEG/polyurethane films. | Zachman AL, Page JM, Prabhakar G, Guelcher SA, Sung HJ | Acta biomaterialia | 23128157 | Acta Biomater | 2013 Feb |
| Does Systemic Inflammation Play a Role in Pediatric Psychosis? | Falcone T, Carlton E, Lee C, Janigro M, Fazio V, Forcen FE, Franco K, Janigro D | Clinical schizophrenia & related psychoses | 23491967 | Clin Schizophr Relat Psychoses | 2015 Summer |
| Scaling and systems biology for integrating multiple organs-on-a-chip. | Wikswo JP, Curtis EL, Eagleton ZE, Evans BC, Kole A, Hofmeister LH, Matloff WJ | Lab on a chip | 23828456 | Lab Chip | 2013 Sep 21 |
| Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts. | Shi M, Majumdar D, Gao Y, Brewer BM, Goodwin CR, McLean JA, Li D, Webb DJ | Lab on a chip | 23736663 | Lab Chip | 2013 Aug 7 |
| Structural characterization of methylenedianiline regioisomers by ion mobility-mass spectrometry, tandem mass spectrometry, and computational strategies: I. Electrospray spectra of 2-ring isomers. | Forsythe JG, Stow SM, Nefzger H, Kwiecien NW, May JC, McLean JA, Hercules DM | Analytical chemistry | 24678803 | Anal Chem | 2014 May 6 |
| Neurovascular unit on a chip: implications for translational applications. | Alcendor DJ, Block FE 3rd, Cliffel DE, Daniels JS, Ellacott KL, Goodwin CR, Hofmeister LH, Li D, Markov DA, May JC, McCawley LJ, McLaughlin B, McLean JA, Niswender KD, Pensabene V, Seale KT, Sherrod SD, Sung HJ, Tabb DL, Webb DJ, Wikswo JP | Stem cell research & therapy | 24564885 | Stem Cell Res Ther | 2013 |
| Femtosecond laser-patterned nanopore arrays for surface-mediated peptide treatment. | Zachman AL, Hofmeister LH, Costa L, Boire TC, Hwang YS, Hofmeister WH, Sung HJ | Nanomedicine : nanotechnology, biology, and medicine | 24090768 | Nanomedicine | 2014 Jan |
| Phage-display-guided nanocarrier targeting to atheroprone vasculature. | Hofmeister LH, Lee SH, Norlander AE, Montaniel KR, Chen W, Harrison DG, Sung HJ | ACS nano | 25768046 | ACS Nano | 2015 |
| Variation in diffusion of gases through PDMS due to plasma surface treatment and storage conditions. | Markov DA, Lillie EM, Garbett SP, McCawley LJ | Biomedical microdevices | 24065585 | Biomed Microdevices | 2014 Feb |
| Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells. | Ghosh C, Hossain M, Solanki J, Najm IM, Marchi N, Janigro D | Epilepsia | 28199000 | Epilepsia | 2017 Apr |
| Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues. | Karolak A, Markov DA, McCawley LJ, Rejniak KA | Journal of the Royal Society, Interface | 29367239 | J R Soc Interface | 2018 Jan |
| Zika Virus Infection of the Human Glomerular Cells: Implications for Viral Reservoirs and Renal Pathogenesis. | Alcendor DJ | The Journal of infectious diseases | 28398522 | J Infect Dis | 2017 Jul 15 |
| Inflammatory pathways of seizure disorders. | Marchi N, Granata T, Janigro D | Trends in neurosciences | 24355813 | Trends Neurosci | 2014 Feb |
| Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients. | McLaughlin B, Gidday JM | Translational stroke research | 24323191 | Transl Stroke Res | 2013 Feb |
| Is phosphorylated tau unique to chronic traumatic encephalopathy? Phosphorylated tau in epileptic brain and chronic traumatic encephalopathy. | Puvenna V, Engeler M, Banjara M, Brennan C, Schreiber P, Dadas A, Bahrami A, Solanki J, Bandyopadhyay A, Morris JK, Bernick C, Ghosh C, Rapp E, Bazarian JJ, Janigro D | Brain research | 26556772 | Brain Res | 2016 Jan 1 |
| IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study. | Wathen C, Janigro D | Epilepsia | 25099305 | Epilepsia | 2014 Aug |
| Profiling and Imaging Ion Mobility-Mass Spectrometry Analysis of Cholesterol and 7-Dehydrocholesterol in Cells Via Sputtered Silver MALDI. | Xu L, Kliman M, Forsythe JG, Korade Z, Hmelo AB, Porter NA, McLean JA | Journal of the American Society for Mass Spectrometry | 25822928 | J Am Soc Mass Spectrom | 2015 Jun |
| In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4(+) T Lymphocytes. | Matta P, Sherrod SD, Marasco CC, Moore DJ, McLean JA, Weitkamp JH | Journal of immunology (Baltimore, Md. : 1950) | 28947540 | J Immunol | 2017 Nov 1 |
| Determination of ion mobility collision cross sections for unresolved isomeric mixtures using tandem mass spectrometry and chemometric deconvolution. | Harper B, Neumann EK, Stow SM, May JC, McLean JA, Solouki T | Analytica chimica acta | 27639144 | Anal Chim Acta | 2016 Oct 5 |
| Emulator-based Bayesian inference on non-proportional scintillation models by compton-edge probing. | Breitenmoser D, Cerutti F, Butterweck G, Kasprzak MM, Mayer S | Nature communications | 38012127 | Nat Commun | 2023 Nov 28 |
| Biophysics and dynamics of natural and engineered stem cell microenvironments. | Keung AJ, Healy KE, Kumar S, Schaffer DV | Wiley interdisciplinary reviews. Systems biology and medicine | 20836010 | Wiley Interdiscip Rev Syst Biol Med | 2010 Jan-Feb |
| Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs. | Liu Y, Sakolish C, Chen Z, Phan DTT, Bender RHF, Hughes CCW, Rusyn I | Toxicology | 32980478 | Toxicology | 2020 Dec 1 |
| Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. | Ma X, Duan Y, Tschudy-Seney B, Roll G, Behbahan IS, Ahuja TP, Tolstikov V, Wang C, McGee J, Khoobyari S, Nolta JA, Willenbring H, Zern MA | Stem cells translational medicine | 23681950 | Stem Cells Transl Med | 2013 Jun |
| Physiologically relevant organs on chips. | Yum K, Hong SG, Healy KE, Lee LP | Biotechnology journal | 24357624 | Biotechnol J | 2014 Jan |
| Transplantable liver organoids made from only three ingredients. | Willenbring H, Soto-Gutierrez A | Cell stem cell | 23910079 | Cell Stem Cell | 2013 Aug 1 |
| In vitro cardiac tissue models: Current status and future prospects. | Mathur A, Ma Z, Loskill P, Jeeawoody S, Healy KE | Advanced drug delivery reviews | 26428618 | Adv Drug Deliv Rev | 2016 Jan 15 |
| WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue. | Loskill P, Sezhian T, Tharp KM, Lee-Montiel FT, Jeeawoody S, Reese WM, Zushin PH, Stahl A, Healy KE | Lab on a chip | 28418430 | Lab Chip | 2017 May 2 |
| Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. | Spencer CI, Baba S, Nakamura K, Hua EA, Sears MA, Fu CC, Zhang J, Balijepalli S, Tomoda K, Hayashi Y, Lizarraga P, Wojciak J, Scheinman MM, Aalto-Setälä K, Makielski JC, January CT, Healy KE, Kamp TJ, Yamanaka S, Conklin BR | Stem cell reports | 25254341 | Stem Cell Reports | 2014 Aug 12 |
| Human iPSC-based cardiac microphysiological system for drug screening applications. | Mathur A, Loskill P, Shao K, Huebsch N, Hong S, Marcus SG, Marks N, Mandegar M, Conklin BR, Lee LP, Healy KE | Scientific reports | 25748532 | Sci Rep | 2015 Mar 9 |
| A therapy for liver failure found in the JNK yard. | Willenbring H, Grompe M | Cell | 23582318 | Cell | 2013 Apr 11 |
| Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales. | Huebsch N, Loskill P, Mandegar MA, Marks NC, Sheehan AS, Ma Z, Mathur A, Nguyen TN, Yoo JC, Judge LM, Spencer CI, Chukka AC, Russell CR, So PL, Conklin BR, Healy KE | Tissue engineering. Part C, Methods | 25333967 | Tissue Eng Part C Methods | 2015 May |
| A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis. | Natividad-Diaz SL, Browne S, Jha AK, Ma Z, Hossainy S, Kurokawa YK, George SC, Healy KE | Biomaterials | 30583150 | Biomaterials | 2019 Feb |
| Mouse liver repopulation with hepatocytes generated from human fibroblasts. | Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S | Nature | 24572354 | Nature | 2014 Apr 3 |
| Three-dimensional filamentous human diseased cardiac tissue model. | Ma Z, Koo S, Finnegan MA, Loskill P, Huebsch N, Marks NC, Conklin BR, Grigoropoulos CP, Healy KE | Biomaterials | 24268663 | Biomaterials | 2014 Feb |
| Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload. | Ma Z, Huebsch N, Koo S, Mandegar MA, Siemons B, Boggess S, Conklin BR, Grigoropoulos CP, Healy KE | Nature biomedical engineering | 31015724 | Nat Biomed Eng | 2018 Dec |
| Self-organizing human cardiac microchambers mediated by geometric confinement. | Ma Z, Wang J, Loskill P, Huebsch N, Koo S, Svedlund FL, Marks NC, Hua EW, Grigoropoulos CP, Conklin BR, Healy KE | Nature communications | 26172574 | Nat Commun | 2015 Jul 14 |
| Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. | Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, Fox CB, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, Desai TA, So PL, Healy KE, Conklin BR | Scientific reports | 27095412 | Sci Rep | 2016 Apr 20 |
| Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency. | Laemmle A, Poms M, Hsu B, Borsuk M, Rüfenacht V, Robinson J, Sadowski MC, Nuoffer JM, Häberle J, Willenbring H | Hepatology (Baltimore, Md.) | 34786702 | Hepatology | 2022 Sep |
| Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development. | Mathur A, Loskill P, Hong S, Lee J, Marcus SG, Dumont L, Conklin BR, Willenbring H, Lee LP, Healy KE | Stem cell research & therapy | 24565415 | Stem Cell Res Ther | 2013 |
| Maladaptive Contractility of 3D Human Cardiac Microtissues to Mechanical Nonuniformity. | Wang C, Koo S, Park M, Vangelatos Z, Hoang P, Conklin BR, Grigoropoulos CP, Healy KE, Ma Z | Advanced healthcare materials | 32090507 | Adv Healthc Mater | 2020 Apr |
| Quantitatively characterizing drug-induced arrhythmic contractile motions of human stem cell-derived cardiomyocytes. | Hoang P, Huebsch N, Bang SH, Siemons BA, Conklin BR, Healy KE, Ma Z, Jacquir S | Biotechnology and bioengineering | 29663322 | Biotechnol Bioeng | 2018 Aug |
| Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cells. | Hoang P, Wang J, Conklin BR, Healy KE, Ma Z | Nature protocols | 29543795 | Nat Protoc | 2018 Apr |
| 3D microtumors in vitro supported by perfused vascular networks. | Sobrino A, Phan DT, Datta R, Wang X, Hachey SJ, Romero-López M, Gratton E, Lee AP, George SC, Hughes CC | Scientific reports | 27549930 | Sci Rep | 2016 Aug 23 |
| Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms. | Shirure VS, George SC | Lab on a chip | 28102869 | Lab Chip | 2017 Feb 14 |
| Deep Learning for Drug Discovery and Cancer Research: Automated Analysis of Vascularization Images. | Urban G, Bache KM, Phan D, Sobrino A, Shmakov AK, Hachey SJ, Hughes C, Baldi P | IEEE/ACM transactions on computational biology and bioinformatics | 29993583 | IEEE/ACM Trans Comput Biol Bioinform | 2019 May-Jun |
| An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy. | Hachey SJ, Movsesyan S, Nguyen QH, Burton-Sojo G, Tankazyan A, Wu J, Hoang T, Zhao D, Wang S, Hatch MM, Celaya E, Gomez S, Chen GT, Davis RT, Nee K, Pervolarakis N, Lawson DA, Kessenbrock K, Lee AP, Lowengrub J, Waterman ML, Hughes CCW | Lab on a chip | 33605955 | Lab Chip | 2021 Apr 7 |
| A three-dimensional in vitro model of tumor cell intravasation. | Ehsan SM, Welch-Reardon KM, Waterman ML, Hughes CC, George SC | Integrative biology : quantitative biosciences from nano to macro | 24763498 | Integr Biol (Camb) | 2014 Jun |
| Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs. | Lee EK, Kurokawa YK, Tu R, George SC, Khine M | Scientific reports | 26139150 | Sci Rep | 2015 Jul 3 |
| Automated detection and analysis of depolarization events in human cardiomyocytes using MaDEC. | Szymanska AF, Heylman C, Datta R, Gratton E, Nenadic Z | Computers in biology and medicine | 27281718 | Comput Biol Med | 2016 Aug 1 |
| Human Induced Pluripotent Stem Cell-Derived Endothelial Cells for Three-Dimensional Microphysiological Systems. | Kurokawa YK, Yin RT, Shang MR, Shirure VS, Moya ML, George SC | Tissue engineering. Part C, Methods | 28622076 | Tissue Eng Part C Methods | 2017 Aug |
| A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays. | Hsu YH, Moya ML, Hughes CC, George SC, Lee AP | Lab on a chip | 23723013 | Lab Chip | 2013 Aug 7 |
| Differential β3 Integrin Expression Regulates the Response of Human Lung and Cardiac Fibroblasts to Extracellular Matrix and Its Components. | Merna N, Fung KM, Wang JJ, King CR, Hansen KC, Christman KL, George SC | Tissue engineering. Part A | 25926101 | Tissue Eng Part A | 2015 Aug |
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| Microfluidic device to control interstitial flow-mediated homotypic and heterotypic cellular communication. | Alonzo LF, Moya ML, Shirure VS, George SC | Lab on a chip | 26190172 | Lab Chip | 2015 Sep 7 |
| Microfluidic device to culture 3D in vitro human capillary networks. | Moya ML, Alonzo LF, George SC | Methods in molecular biology (Clifton, N.J.) | 24155229 | Methods Mol Biol | 2014 |
| Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening. | Kurokawa YK, George SC | Advanced drug delivery reviews | 26212156 | Adv Drug Deliv Rev | 2016 Jan 15 |
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| Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes. | Datta R, Heylman C, George SC, Gratton E | Biomedical optics express | 27231614 | Biomed Opt Express | 2016 May 1 |
| A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications. | Phan DTT, Wang X, Craver BM, Sobrino A, Zhao D, Chen JC, Lee LYN, George SC, Lee AP, Hughes CCW | Lab on a chip | 28092382 | Lab Chip | 2017 Jan 31 |
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| Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. | Heylman C, Datta R, Sobrino A, George S, Gratton E | PloS one | 26695765 | PLoS One | 2015 |
| Human Induced Pluripotent Stem-Cardiac-Endothelial-Tumor-on-a-Chip to Assess Anticancer Efficacy and Cardiotoxicity. | Weng KC, Kurokawa YK, Hajek BS, Paladin JA, Shirure VS, George SC | Tissue engineering. Part C, Methods | 31797733 | Tissue Eng Part C Methods | 2020 Jan |
| 3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels. | Wang X, Phan DTT, George SC, Hughes CCW, Lee AP | Methods in molecular biology (Clifton, N.J.) | 28634954 | Methods Mol Biol | 2017 |
| Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels. | Wang X, Phan DT, Sobrino A, George SC, Hughes CC, Lee AP | Lab on a chip | 26616908 | Lab Chip | 2016 Jan 21 |
| Organ-on-a-chip model of vascularized human bone marrow niches. | Glaser DE, Curtis MB, Sariano PA, Rollins ZA, Shergill BS, Anand A, Deely AM, Shirure VS, Anderson L, Lowen JM, Ng NR, Weilbaecher K, Link DC, George SC | Biomaterials | 34810038 | Biomaterials | 2022 Jan |
| Integrating in vitro organ-specific function with the microcirculation. | Moya ML, George SC | Current opinion in chemical engineering | 24729953 | Curr Opin Chem Eng | 2014 Feb 1 |
| An integrated in vitro model of perfused tumor and cardiac tissue. | Moya M, Tran D, George SC | Stem cell research & therapy | 24565445 | Stem Cell Res Ther | 2013 |
| A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening. | Heylman C, Sobrino A, Shirure VS, Hughes CC, George SC | Experimental biology and medicine (Maywood, N.J.) | 24740872 | Exp Biol Med (Maywood) | 2014 Sep |
| Cancer-associated fibroblasts support vascular growth through mechanical force. | Sewell-Loftin MK, Bayer SVH, Crist E, Hughes T, Joison SM, Longmore GD, George SC | Scientific reports | 28974764 | Sci Rep | 2017 Oct 3 |
| Low levels of physiological interstitial flow eliminate morphogen gradients and guide angiogenesis. | Shirure VS, Lezia A, Tao A, Alonzo LF, George SC | Angiogenesis | 28608153 | Angiogenesis | 2017 Nov |
| Blood-brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood-central nervous system interface. | Phan DT, Bender RHF, Andrejecsk JW, Sobrino A, Hachey SJ, George SC, Hughes CC | Experimental biology and medicine (Maywood, N.J.) | 28195514 | Exp Biol Med (Maywood) | 2017 Nov |
| Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes. | Robertson C, Tran DD, George SC | Stem cells (Dayton, Ohio) | 23355363 | Stem Cells | 2013 May |
| The vascular niche in next generation microphysiological systems. | Ewald ML, Chen YH, Lee AP, Hughes CCW | Lab on a chip | 34396383 | Lab Chip | 2021 Sep 7 |
| Applications of tumor chip technology. | Hachey SJ, Hughes CCW | Lab on a chip | 30156248 | Lab Chip | 2018 Sep 26 |
| Tumor-on-a-chip platform to investigate progression and drug sensitivity in cell lines and patient-derived organoids. | Shirure VS, Bi Y, Curtis MB, Lezia A, Goedegebuure MM, Goedegebuure SP, Aft R, Fields RC, George SC | Lab on a chip | 30393802 | Lab Chip | 2018 Dec 7 |
| Executive summary of the 12th HHT international scientific conference. | Andrejecsk JW, Hosman AE, Botella LM, Shovlin CL, Arthur HM, Dupuis-Girod S, Buscarini E, Hughes CCW, Lebrin F, Mummery CL, Post MC, Mager JJ | Angiogenesis | 29147802 | Angiogenesis | 2018 Feb |
| Vessel network formation in response to intermittent hypoxia is frequency dependent. | Ehsan SM, George SC | Journal of bioscience and bioengineering | 25735591 | J Biosci Bioeng | 2015 Sep |
| Biomimetic on-a-chip platforms for studying cancer metastasis. | Lee E, Song HG, Chen CS | Current opinion in chemical engineering | 27570735 | Curr Opin Chem Eng | 2016 Feb |
| Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. | Fang JS, Coon BG, Gillis N, Chen Z, Qiu J, Chittenden TW, Burt JM, Schwartz MA, Hirschi KK | Nature communications | 29247167 | Nat Commun | 2017 Dec 15 |
| Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification. | Qiu J, Nordling S, Vasavada HH, Butcher EC, Hirschi KK | Cell reports | 33264627 | Cell Rep | 2020 Dec 1 |
| Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers. | Chen AX, Chhabra A, Song HG, Fleming HE, Chen CS, Bhatia SN | Advanced functional materials | 33776613 | Adv Funct Mater | 2020 Nov 25 |
| HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease. | Vunjak-Novakovic G, Bhatia S, Chen C, Hirschi K | Stem cell research & therapy | 24565063 | Stem Cell Res Ther | 2013 |
| Development of a new method for the isolation and culture of pulmonary arterial endothelial cells from rat pulmonary arteries. | Peng G, Wen X, Shi Y, Jiang Y, Hu G, Zhou Y, Ran P | Journal of vascular research | 24192526 | J Vasc Res | 2013 |
| Macrophages modulate engineered human tissues for enhanced vascularization and healing. | Spiller KL, Freytes DO, Vunjak-Novakovic G | Annals of biomedical engineering | 25331098 | Ann Biomed Eng | 2015 Mar |
| 3D culture models of tissues under tension. | Eyckmans J, Chen CS | Journal of cell science | 27909243 | J Cell Sci | 2017 Jan 1 |
| Tissue-Engineering for the Study of Cardiac Biomechanics. | Ma SP, Vunjak-Novakovic G | Journal of biomechanical engineering | 26720588 | J Biomech Eng | 2016 Feb |
| Isolation of Murine Embryonic Hemogenic Endothelial Cells. | Fang JS, Gritz EC, Marcelo KL, Hirschi KK | Journal of visualized experiments : JoVE | 27341393 | J Vis Exp | 2016 Jun 17 |
| Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma. | Villasante A, Sakaguchi K, Kim J, Cheung NK, Nakayama M, Parsa H, Okano T, Shimizu T, Vunjak-Novakovic G | Theranostics | 29158813 | Theranostics | 2017 |
| Multifaceted Roles of Connexin 43 in Stem Cell Niches. | Genet N, Bhatt N, Bourdieu A, Hirschi KK | Current stem cell reports | 29600160 | Curr Stem Cell Rep | 2018 |
| Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening. | Zhao R, Chen CS, Reich DH | Biomaterials | 24630092 | Biomaterials | 2014 Jun |
| The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine. | Martins AM, Vunjak-Novakovic G, Reis RL | Stem cell reviews and reports | 24425421 | Stem Cell Rev Rep | 2014 Apr |
| Cell and tissue engineering for liver disease. | Bhatia SN, Underhill GH, Zaret KS, Fox IJ | Science translational medicine | 25031271 | Sci Transl Med | 2014 Jul 16 |
| Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro. | Ng S, Schwartz RE, March S, Galstian A, Gural N, Shan J, Prabhu M, Mota MM, Bhatia SN | Stem cell reports | 25660406 | Stem Cell Reports | 2015 Mar 10 |
| Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype. | Ronaldson-Bouchard K, Yeager K, Teles D, Chen T, Ma S, Song L, Morikawa K, Wobma HM, Vasciaveo A, Ruiz EC, Yazawa M, Vunjak-Novakovic G | Nature protocols | 31492957 | Nat Protoc | 2019 Oct |
| The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation. | Chavkin NW, Sano S, Wang Y, Oshima K, Ogawa H, Horitani K, Sano M, MacLauchlan S, Nelson A, Setia K, Vippa T, Watanabe Y, Saucerman JJ, Hirschi KK, Gokce N, Walsh K | Journal of the American Heart Association | 34155901 | J Am Heart Assoc | 2021 Jul 6 |
| Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients. | Baker BM, Trappmann B, Stapleton SC, Toro E, Chen CS | Lab on a chip | 23787488 | Lab Chip | 2013 Aug 21 |
| Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice. | Kam CY, Singh ID, Gonzalez DG, Matte-Martone C, Solá P, Solanas G, Bonjoch J, Marsh E, Hirschi KK, Greco V | Cell | 37167971 | Cell | 2023 May 25 |
| A vascularized model of the human liver mimics regenerative responses. | Chhabra A, Song HG, Grzelak KA, Polacheck WJ, Fleming HE, Chen CS, Bhatia SN | Proceedings of the National Academy of Sciences of the United States of America | 35763565 | Proc Natl Acad Sci U S A | 2022 Jul 12 |
| Rational engineering of lung alveolar epithelium. | Leiby KL, Yuan Y, Ng R, Raredon MSB, Adams TS, Baevova P, Greaney AM, Hirschi KK, Campbell SG, Kaminski N, Herzog EL, Niklason LE | NPJ Regenerative medicine | 37117221 | NPJ Regen Med | 2023 Apr 28 |
| Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone. | Genet N, Genet G, Chavkin NW, Paila U, Fang JS, Vasavada HH, Goldberg JS, Acharya BR, Bhatt NS, Baker K, McDonnell SP, Huba M, Sankaranarayanan D, Ma GZM, Eichmann A, Thomas JL, Ffrench-Constant C, Hirschi KK | Cell reports | 37043357 | Cell Rep | 2023 Apr 25 |
| Portable bioreactor for perfusion and electrical stimulation of engineered cardiac tissue. | Tandon N, Taubman A, Cimetta E, Saccenti L, Vunjak-Novakovic G | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | 24111161 | Annu Int Conf IEEE Eng Med Biol Soc | 2013 |
| Patterning vascular networks in vivo for tissue engineering applications. | Chaturvedi RR, Stevens KR, Solorzano RD, Schwartz RE, Eyckmans J, Baranski JD, Stapleton SC, Bhatia SN, Chen CS | Tissue engineering. Part C, Methods | 25390971 | Tissue Eng Part C Methods | 2015 May |
| Myocardial tissue engineering: in vitro models. | Vunjak Novakovic G, Eschenhagen T, Mummery C | Cold Spring Harbor perspectives in medicine | 24591534 | Cold Spring Harb Perspect Med | 2014 Mar 1 |
| Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells. | Cimetta E, Sirabella D, Yeager K, Davidson K, Simon J, Moon RT, Vunjak-Novakovic G | Lab on a chip | 23232509 | Lab Chip | 2013 Feb 7 |
| Physical influences on stem cells. | Vunjak-Novakovic G | Stem cell research & therapy | 24476419 | Stem Cell Res Ther | 2013 Dec 24 |
| Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes. | Freytes DO, O'Neill JD, Duan-Arnold Y, Wrona EA, Vunjak-Novakovic G | Methods in molecular biology (Clifton, N.J.) | 25070328 | Methods Mol Biol | 2014 |
| Fluid shear stress threshold regulates angiogenic sprouting. | Galie PA, Nguyen DH, Choi CK, Cohen DM, Janmey PA, Chen CS | Proceedings of the National Academy of Sciences of the United States of America | 24843171 | Proc Natl Acad Sci U S A | 2014 Jun 3 |
| Forces and mechanotransduction in 3D vascular biology. | Kutys ML, Chen CS | Current opinion in cell biology | 27209346 | Curr Opin Cell Biol | 2016 Oct |
| A non-canonical Notch complex regulates adherens junctions and vascular barrier function. | Polacheck WJ, Kutys ML, Yang J, Eyckmans J, Wu Y, Vasavada H, Hirschi KK, Chen CS | Nature | 29160307 | Nature | 2017 Dec 14 |
| Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. | Ronaldson-Bouchard K, Vunjak-Novakovic G | Cell stem cell | 29499151 | Cell Stem Cell | 2018 Mar 1 |
| Tissue Engineering and Regenerative Medicine 2015: A Year in Review. | Wobma H, Vunjak-Novakovic G | Tissue engineering. Part B, Reviews | 26714410 | Tissue Eng Part B Rev | 2016 Apr |
| Modular Assembly Approach to Engineer Geometrically Precise Cardiovascular Tissue. | Lee BW, Liu B, Pluchinsky A, Kim N, Eng G, Vunjak-Novakovic G | Advanced healthcare materials | 26865105 | Adv Healthc Mater | 2016 Apr 20 |
| Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. | Eng G, Lee BW, Protas L, Gagliardi M, Brown K, Kass RS, Keller G, Robinson RB, Vunjak-Novakovic G | Nature communications | 26785135 | Nat Commun | 2016 Jan 19 |
| Engineered Microvasculature in PDMS Networks Using Endothelial Cells Derived from Human Induced Pluripotent Stem Cells. | Sivarapatna A, Ghaedi M, Xiao Y, Han E, Aryal B, Zhou J, Fernandez-Hernando C, Qyang Y, Hirschi KK, Niklason LE | Cell transplantation | 28901188 | Cell Transplant | 2017 Aug |
| Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification. | Logan DJ, Shan J, Bhatia SN, Carpenter AE | Methods (San Diego, Calif.) | 26687239 | Methods | 2016 Mar 1 |
| FGF-dependent metabolic control of vascular development. | Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M | Nature | 28467822 | Nature | 2017 May 11 |
| Tissue engineering of human hair follicles using a biomimetic developmental approach. | Abaci HE, Coffman A, Doucet Y, Chen J, Jacków J, Wang E, Guo Z, Shin JU, Jahoda CA, Christiano AM | Nature communications | 30546011 | Nat Commun | 2018 Dec 13 |
| Biomechanical regulation of drug sensitivity in an engineered model of human tumor. | Marturano-Kruik A, Villasante A, Yaeger K, Ambati SR, Chramiec A, Raimondi MT, Vunjak-Novakovic G | Biomaterials | 29040875 | Biomaterials | 2018 Jan |
| Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues. | Song HG, Lammers A, Sundaram S, Rubio L, Chen AX, Li L, Eyckmans J, Bhatia SN, Chen CS | Advanced functional materials | 33613149 | Adv Funct Mater | 2020 Nov 25 |
| Endothelial Cell Development and Its Application to Regenerative Medicine. | Qiu J, Hirschi KK | Circulation research | 31518171 | Circ Res | 2019 Aug 2 |
| Directed Differentiation of Hemogenic Endothelial Cells from Human Pluripotent Stem Cells. | Nelson EA, Qiu J, Chavkin NW, Hirschi KK | Journal of visualized experiments : JoVE | 33871448 | J Vis Exp | 2021 Mar 31 |
| Bioengineering heart tissue for in vitro testing. | Cimetta E, Godier-Furnémont A, Vunjak-Novakovic G | Current opinion in biotechnology | 23932513 | Curr Opin Biotechnol | 2013 Oct |
| Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro. | Nguyen DH, Stapleton SC, Yang MT, Cha SS, Choi CK, Galie PA, Chen CS | Proceedings of the National Academy of Sciences of the United States of America | 23569284 | Proc Natl Acad Sci U S A | 2013 Apr 23 |
| Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling. | Cimetta E, Cannizzaro C, James R, Biechele T, Moon RT, Elvassore N, Vunjak-Novakovic G | Lab on a chip | 20936235 | Lab Chip | 2010 Dec 7 |
| Tissue engineering of the heart: An evolving paradigm. | Vunjak-Novakovic G | The Journal of thoracic and cardiovascular surgery | 27692954 | J Thorac Cardiovasc Surg | 2017 Mar |
| milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues. | Tamargo MA, Nash TR, Fleischer S, Kim Y, Vila OF, Yeager K, Summers M, Zhao Y, Lock R, Chavez M, Costa T, Vunjak-Novakovic G | ACS biomaterials science & engineering | 34668692 | ACS Biomater Sci Eng | 2021 Nov 8 |
| Endothelial Cell Differentiation and Hemogenic Specification. | Aragon JW, Hirschi KK | Cold Spring Harbor perspectives in medicine | 35193895 | Cold Spring Harb Perspect Med | 2022 Jul 29 |
| Understanding neural stem cell regulation in vivo and applying the insights to cell therapy for strokes. | Genet N, Hirschi KK | Regenerative medicine | 34498495 | Regen Med | 2021 Sep |
| Induced pluripotent stem cells for regenerative medicine. | Hirschi KK, Li S, Roy K | Annual review of biomedical engineering | 24905879 | Annu Rev Biomed Eng | 2014 Jul 11 |
| The magic touch: endothelial cells muscle-up adipose. | Martin KA, Hirschi KK | Circulation research | 25301822 | Circ Res | 2014 Oct 10 |
| A DNA-based molecular probe for optically reporting cellular traction forces. | Blakely BL, Dumelin CE, Trappmann B, McGregor LM, Choi CK, Anthony PC, Duesterberg VK, Baker BM, Block SM, Liu DR, Chen CS | Nature methods | 25306545 | Nat Methods | 2014 Dec |
| Bioengineered tumors. | Villasante A, Vunjak-Novakovic G | Bioengineered | 25616977 | Bioengineered | 2015 |
| Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers. | Wang H, Abhilash AS, Chen CS, Wells RG, Shenoy VB | Biophysical journal | 25468338 | Biophys J | 2014 Dec 2 |
| In vitro Models of Ischemia-Reperfusion Injury. | Chen T, Vunjak-Novakovic G | Regenerative engineering and translational medicine | 30393757 | Regen Eng Transl Med | 2018 Sep |
| A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling. | Nguyen DT, Lee E, Alimperti S, Norgard RJ, Wong A, Lee JJ, Eyckmans J, Stanger BZ, Chen CS | Science advances | 31489365 | Sci Adv | 2019 Aug |
| Human bone perivascular niche-on-a-chip for studying metastatic colonization. | Marturano-Kruik A, Nava MM, Yeager K, Chramiec A, Hao L, Robinson S, Guo E, Raimondi MT, Vunjak-Novakovic G | Proceedings of the National Academy of Sciences of the United States of America | 29363599 | Proc Natl Acad Sci U S A | 2018 Feb 6 |
| Advanced maturation of human cardiac tissue grown from pluripotent stem cells. | Ronaldson-Bouchard K, Ma SP, Yeager K, Chen T, Song L, Sirabella D, Morikawa K, Teles D, Yazawa M, Vunjak-Novakovic G | Nature | 29618819 | Nature | 2018 Apr |
| "The state of the heart": Recent advances in engineering human cardiac tissue from pluripotent stem cells. | Sirabella D, Cimetta E, Vunjak-Novakovic G | Experimental biology and medicine (Maywood, N.J.) | 26069271 | Exp Biol Med (Maywood) | 2015 Aug |
| Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors. | Bagley AF, Scherz-Shouval R, Galie PA, Zhang AQ, Wyckoff J, Whitesell L, Chen CS, Lindquist S, Bhatia SN | Cancer research | 26122846 | Cancer Res | 2015 Aug 15 |
| Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. | Shlomai A, Schwartz RE, Ramanan V, Bhatta A, de Jong YP, Bhatia SN, Rice CM | Proceedings of the National Academy of Sciences of the United States of America | 25092305 | Proc Natl Acad Sci U S A | 2014 Aug 19 |
| Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy. | Li F, Xu T, Nguyen DH, Huang X, Chen CS, Zhou C | Journal of biomedical optics | 24395588 | J Biomed Opt | 2014 Jan |
| Non-destructive vacuum-assisted measurement of lung elastic modulus. | Chen J, Mir M, Pinezich MR, O'Neill JD, Guenthart BA, Bacchetta M, Vunjak-Novakovic G, Huang SXL, Kim J | Acta biomaterialia | 34192570 | Acta Biomater | 2021 Sep 1 |
| Laminar flow downregulates Notch activity to promote lymphatic sprouting. | Choi D, Park E, Jung E, Seong YJ, Yoo J, Lee E, Hong M, Lee S, Ishida H, Burford J, Peti-Peterdi J, Adams RH, Srikanth S, Gwack Y, Chen CS, Vogel HJ, Koh CJ, Wong AK, Hong YK | The Journal of clinical investigation | 28263185 | J Clin Invest | 2017 Apr 3 |
| Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. | Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE | Cell reports | 28009297 | Cell Rep | 2016 Dec 20 |
| (*) Extracellular Vesicles and Their Versatile Roles in Tissue Engineering. | Jay SM, Vunjak-Novakovic G | Tissue engineering. Part A | 28649910 | Tissue Eng Part A | 2017 Nov |
| Bioengineered Models of Solid Human Tumors for Cancer Research. | Marturano-Kruik A, Villasante A, Vunjak-Novakovic G | Methods in molecular biology (Clifton, N.J.) | 27115504 | Methods Mol Biol | 2016 |
| Next generation human skin constructs as advanced tools for drug development. | Abaci HE, Guo Z, Doucet Y, Jacków J, Christiano A | Experimental biology and medicine (Maywood, N.J.) | 28592171 | Exp Biol Med (Maywood) | 2017 Nov |
| Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues. | Feric NT, Radisic M | Advanced drug delivery reviews | 25956564 | Adv Drug Deliv Rev | 2016 Jan 15 |
| Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. | Genet G, Genet N, Paila U, Cain SR, Cwiek A, Chavkin NW, Serbulea V, Figueras A, Cerdà P, McDonnell SP, Sankaranarayanan D, Huba M, Nelson EA, Riera-Mestre A, Hirschi KK | Circulation | 38126211 | Circulation | 2024 Mar 19 |
| MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis. | Wu Y, Paila U, Genet G, Hirschi KK | Developmental cell | 37295435 | Dev Cell | 2023 Jul 24 |
| Bioreactor engineering of stem cell environments. | Tandon N, Marolt D, Cimetta E, Vunjak-Novakovic G | Biotechnology advances | 23531529 | Biotechnol Adv | 2013 Nov 15 |
| Vascular endothelial cell specification in health and disease. | Marziano C, Genet G, Hirschi KK | Angiogenesis | 33844116 | Angiogenesis | 2021 May |
| Microscale technologies for regulating human stem cell differentiation. | Cimetta E, Vunjak-Novakovic G | Experimental biology and medicine (Maywood, N.J.) | 24737735 | Exp Biol Med (Maywood) | 2014 Sep |
| Stress-Induced Premature Senescence of Endothelial and Endothelial Progenitor Cells. | Goligorsky MS, Hirschi K | Advances in pharmacology (San Diego, Calif.) | 27451101 | Adv Pharmacol | 2016 |
| Microfabricated blood vessels for modeling the vascular transport barrier. | Polacheck WJ, Kutys ML, Tefft JB, Chen CS | Nature protocols | 30953042 | Nat Protoc | 2019 May |
| The molecular basis of endothelial cell plasticity. | Dejana E, Hirschi KK, Simons M | Nature communications | 28181491 | Nat Commun | 2017 Feb 9 |
| Isolation of Highly Purified and Viable Retinal Endothelial Cells. | Chavkin NW, Walsh K, Hirschi KK | Journal of vascular research | 33022674 | J Vasc Res | 2021 |
| Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety. | Chramiec A, Teles D, Yeager K, Marturano-Kruik A, Pak J, Chen T, Hao L, Wang M, Lock R, Tavakol DN, Lee MB, Kim J, Ronaldson-Bouchard K, Vunjak-Novakovic G | Lab on a chip | 32955072 | Lab Chip | 2020 Nov 24 |
| Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells. | Liu B, Lee BW, Nakanishi K, Villasante A, Williamson R, Metz J, Kim J, Kanai M, Bi L, Brown K, Di Paolo G, Homma S, Sims PA, Topkara VK, Vunjak-Novakovic G | Nature biomedical engineering | 30271672 | Nat Biomed Eng | 2018 May |
| Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell-endothelial cell-regulated barrier function. | Alimperti S, Mirabella T, Bajaj V, Polacheck W, Pirone DM, Duffield J, Eyckmans J, Assoian RK, Chen CS | Proceedings of the National Academy of Sciences of the United States of America | 28765370 | Proc Natl Acad Sci U S A | 2017 Aug 15 |
| Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury. | McCurley A, Alimperti S, Campos-Bilderback SB, Sandoval RM, Calvino JE, Reynolds TL, Quigley C, Mugford JW, Polacheck WJ, Gomez IG, Dovey J, Marsh G, Huang A, Qian F, Weinreb PH, Dolinski BM, Moore S, Duffield JS, Chen CS, Molitoris BA, Violette SM, Crackower MA | Journal of the American Society of Nephrology : JASN | 28062569 | J Am Soc Nephrol | 2017 Jun |
| Modeling tumor microenvironments using custom-designed biomaterial scaffolds. | Liu Z, Vunjak-Novakovic G | Current opinion in chemical engineering | 27152253 | Curr Opin Chem Eng | 2016 Feb |
| Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production. | Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi MM, Bender JR, Morrison AR | Arteriosclerosis, thrombosis, and vascular biology | 27834690 | Arterioscler Thromb Vasc Biol | 2017 Feb |
| Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues. | Li CY, Stevens KR, Schwartz RE, Alejandro BS, Huang JH, Bhatia SN | Tissue engineering. Part A | 24498910 | Tissue Eng Part A | 2014 Aug |
| Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells. | Coşkun S, Chao H, Vasavada H, Heydari K, Gonzales N, Zhou X, de Crombrugghe B, Hirschi KK | Cell reports | 25310984 | Cell Rep | 2014 Oct 23 |
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| Platforms to test the temporospatial capabilities of carrier systems in delivering growth factors to benefit vascular bioengineering. | Argueta LB, Niles JA, Sakamoto J, Liu X, Vega SP, Frank L, Paessler M, Cortiella J, Nichols JE | Nanomedicine : nanotechnology, biology, and medicine | 34147665 | Nanomedicine | 2021 Aug |
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| A High-Throughput Mechanical Activator for Cartilage Engineering Enables Rapid Screening of in vitro Response of Tissue Models to Physiological and Supra-Physiological Loads. | Capuana E, Marino D, Di Gesù R, La Carrubba V, Brucato V, Tuan RS, Gottardi R | Cells, tissues, organs | 34261061 | Cells Tissues Organs | 2022 |
| A Mesoscale 3D Culture System for Native and Engineered Biphasic Tissues: Application to the Osteochondral Unit. | Chiesa I, Di Gesù R, Overholt KJ, Gottardi R | Methods in molecular biology (Clifton, N.J.) | 34520018 | Methods Mol Biol | 2022 |
| Projection Stereolithographic Fabrication of Human Adipose Stem Cell-Incorporated Biodegradable Scaffolds for Cartilage Tissue Engineering. | Sun AX, Lin H, Beck AM, Kilroy EJ, Tuan RS | Frontiers in bioengineering and biotechnology | 26347860 | Front Bioeng Biotechnol | 2015 |
| Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1β. | Lin H, Lozito TP, Alexander PG, Gottardi R, Tuan RS | Molecular pharmaceutics | 24830762 | Mol Pharm | 2014 Jul 7 |
| Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis. | Lozito TP, Alexander PG, Lin H, Gottardi R, Cheng AW, Tuan RS | Stem cell research & therapy | 24564995 | Stem Cell Res Ther | 2013 |
| Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor. | Diederichs S, Tuan RS | Stem cells and development | 24625206 | Stem Cells Dev | 2014 Jul 15 |
| Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases. | Alexander PG, Gottardi R, Lin H, Lozito TP, Tuan RS | Experimental biology and medicine (Maywood, N.J.) | 24994814 | Exp Biol Med (Maywood) | 2014 Sep |
| Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies. | Hofer HR, Tuan RS | Stem cell research & therapy | 27612948 | Stem Cell Res Ther | 2016 Sep 9 |
| Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1β/nerve growth factor signaling. | Jiang Y, Hu C, Yu S, Yan J, Peng H, Ouyang HW, Tuan RS | Arthritis research & therapy | 26577823 | Arthritis Res Ther | 2015 Nov 17 |
| Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial. | Chamberlain JM, Kapur J, Shinnar S, Elm J, Holsti M, Babcock L, Rogers A, Barsan W, Cloyd J, Lowenstein D, Bleck TP, Conwit R, Meinzer C, Cock H, Fountain NB, Underwood E, Connor JT, Silbergleit R, Neurological Emergencies Treatment Trials, Pediatric Emergency Care Applied Research Network investigators | Lancet (London, England) | 32203691 | Lancet | 2020 Apr 11 |
| Electroencephalographic Seizures in Emergency Department Patients After Treatment for Convulsive Status Epilepticus. | Zehtabchi S, Silbergleit R, Chamberlain JM, Shinnar S, Elm JJ, Underwood E, Rosenthal ES, Bleck TP, Kapur J | Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society | 33337664 | J Clin Neurophysiol | 2022 Sep 1 |
| Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus. | Connor JT, Elm JJ, Broglio KR, ESETT and ADAPT-IT Investigators | Journal of clinical epidemiology | 23849147 | J Clin Epidemiol | 2013 Aug |
| Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. | Johnston SC, Easton JD, Farrant M, Barsan W, Battenhouse H, Conwit R, Dillon C, Elm J, Lindblad A, Morgenstern L, Poisson SN, Palesch Y | International journal of stroke : official journal of the International Stroke Society | 23879752 | Int J Stroke | 2013 Aug |
| Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis. | Legocki LJ, Meurer WJ, Frederiksen S, Lewis RJ, Durkalski VL, Berry DA, Barsan WG, Fetters MD | BMC medical ethics | 25933921 | BMC Med Ethics | 2015 May 3 |
| The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial: an adaptive trial design case study. | Connor JT, Broglio KR, Durkalski V, Meurer WJ, Johnston KC | Trials | 25885963 | Trials | 2015 Mar 4 |
| Lessons from the Established Status Epilepticus Treatment Trial. | Cock HR, Coles LD, Elm J, Silbergleit R, Chamberlain JM, Cloyd JC, Fountain N, Shinnar S, Lowenstein D, Conwit R, Bleck TP, Kapur J | Epilepsy & behavior : E&B | 31653603 | Epilepsy Behav | 2019 Dec |
| Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP): study protocol for a multicenter, randomized, adaptive allocation clinical trial to identify the optimal duration of induced hypothermia for neuroprotection in comatose, adult survivors of after out-of-hospital cardiac arrest. | Meurer WJ, Schmitzberger FF, Yeatts S, Ramakrishnan V, Abella B, Aufderheide T, Barsan W, Benoit J, Berry S, Black J, Bozeman N, Broglio K, Brown J, Brown K, Carlozzi N, Caveney A, Cho SM, Chung-Esaki H, Clevenger R, Conwit R, Cooper R, Crudo V, Daya M, Harney D, Hsu C, Johnson NJ, Khan I, Khosla S, Kline P, Kratz A, Kudenchuk P, Lewis RJ, Madiyal C, Meyer S, Mosier J, Mouammar M, Neth M, O'Neil B, Paxton J, Perez S, Perman S, Sozener C, Speers M, Spiteri A, Stevenson V, Sunthankar K, Tonna J, Youngquist S, Geocadin R, Silbergleit R, ICECAP trial investigators | Trials | 39044295 | Trials | 2024 Jul 23 |
| The established status epilepticus trial 2013. | Bleck T, Cock H, Chamberlain J, Cloyd J, Connor J, Elm J, Fountain N, Jones E, Lowenstein D, Shinnar S, Silbergleit R, Treiman D, Trinka E, Kapur J | Epilepsia | 24001084 | Epilepsia | 2013 Sep |
| An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project. | Meurer WJ, Lewis RJ, Tagle D, Fetters MD, Legocki L, Berry S, Connor J, Durkalski V, Elm J, Zhao W, Frederiksen S, Silbergleit R, Palesch Y, Berry DA, Barsan WG | Annals of emergency medicine | 22424650 | Ann Emerg Med | 2012 Oct |
| Attitudes and opinions regarding confirmatory adaptive clinical trials: a mixed methods analysis from the Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT) project. | Meurer WJ, Legocki L, Mawocha S, Frederiksen SM, Guetterman TC, Barsan W, Lewis R, Berry D, Fetters M | Trials | 27473126 | Trials | 2016 Jul 29 |
| Effect of insurance status on postacute care among working age stroke survivors. | Skolarus LE, Meurer WJ, Burke JF, Prvu Bettger J, Lisabeth LD | Neurology | 22551730 | Neurology | 2012 May 15 |
| Spinal cord injury neuroprotection and the promise of flexible adaptive clinical trials. | Meurer WJ, Barsan WG | World neurosurgery | 23851207 | World Neurosurg | 2014 Sep-Oct |
| Early Neurologic Recovery, Practice Pattern Variation, and the Risk of Endotracheal Intubation Following Established Status Epilepticus. | Rosenthal ES, Elm JJ, Ingles J, Rogers AJ, Terndrup TE, Holsti M, Thomas DG, Babcock L, Okada PJ, Lipsky RH, Miller JB, Hickey RW, Barra ME, Bleck TP, Cloyd JC, Silbergleit R, Lowenstein DH, Coles LD, Kapur J, Shinnar S, Chamberlain JM, Established Status Epilepticus Treatment Trial Study Group | Neurology | 34032604 | Neurology | 2021 May 11 |
| Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus. | Kapur J, Elm J, Chamberlain JM, Barsan W, Cloyd J, Lowenstein D, Shinnar S, Conwit R, Meinzer C, Cock H, Fountain N, Connor JT, Silbergleit R, NETT and PECARN Investigators | The New England journal of medicine | 31774955 | N Engl J Med | 2019 Nov 28 |
| Adaptive clinical trials: a partial remedy for the therapeutic misconception? | Meurer WJ, Lewis RJ, Berry DA | JAMA | 22692168 | JAMA | 2012 Jun 13 |
| Intracerebral hemorrhage mortality is not changing despite declining incidence. | Zahuranec DB, Lisabeth LD, Sánchez BN, Smith MA, Brown DL, Garcia NM, Skolarus LE, Meurer WJ, Burke JF, Adelman EE, Morgenstern LB | Neurology | 24838789 | Neurology | 2014 Jun 17 |
| Comparison of Bayesian vs Frequentist Adaptive Trial Design in the Stroke Hyperglycemia Insulin Network Effort Trial. | Broglio K, Meurer WJ, Durkalski V, Pauls Q, Connor J, Berry D, Lewis RJ, Johnston KC, Barsan WG | JAMA network open | 35544137 | JAMA Netw Open | 2022 May 2 |
| Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study. | Guetterman TC, Fetters MD, Legocki LJ, Mawocha S, Barsan WG, Lewis RJ, Berry DA, Meurer WJ | Clinical research and regulatory affairs | 26622163 | Clin Res Regul Aff | 2015 Oct 2 |
| A conceptual model for the development process of confirmatory adaptive clinical trials within an emergency research network. | Mawocha SC, Fetters MD, Legocki LJ, Guetterman TC, Frederiksen S, Barsan WG, Lewis RJ, Berry DA, Meurer WJ | Clinical trials (London, England) | 28135827 | Clin Trials | 2017 Jun |
| Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip. | Grosberg A, Alford PW, McCain ML, Parker KK | Lab on a chip | 22072288 | Lab Chip | 2011 Dec 21 |
| Microfluidic heart on a chip for higher throughput pharmacological studies. | Agarwal A, Goss JA, Cho A, McCain ML, Parker KK | Lab on a chip | 23807141 | Lab Chip | 2013 Sep 21 |
| Muscle on a chip: in vitro contractility assays for smooth and striated muscle. | Grosberg A, Nesmith AP, Goss JA, Brigham MD, McCain ML, Parker KK | Journal of pharmacological and toxicological methods | 22521339 | J Pharmacol Toxicol Methods | 2012 May-Jun |
| The contribution of cellular mechanotransduction to cardiomyocyte form and function. | Sheehy SP, Grosberg A, Parker KK | Biomechanics and modeling in mechanobiology | 22772714 | Biomech Model Mechanobiol | 2012 Nov |
| A mini-microscope for in situ monitoring of cells. | Kim SB, Koo KI, Bae H, Dokmeci MR, Hamilton GA, Bahinski A, Kim SM, Ingber DE, Khademhosseini A | Lab on a chip | 22911426 | Lab Chip | 2012 Oct 21 |
| A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. | Huh D, Leslie DC, Matthews BD, Fraser JP, Jurek S, Hamilton GA, Thorneloe KS, McAlexander MA, Ingber DE | Science translational medicine | 23136042 | Sci Transl Med | 2012 Nov 7 |
| Clear castable polyurethane elastomer for fabrication of microfluidic devices. | Domansky K, Leslie DC, McKinney J, Fraser JP, Sliz JD, Hamkins-Indik T, Hamilton GA, Bahinski A, Ingber DE | Lab on a chip | 23954953 | Lab Chip | 2013 Oct 7 |
| Micropatterning Alginate Substrates for in vitro Cardiovascular Muscle on a Chip. | Agarwal A, Farouz Y, Nesmith AP, Deravi LF, McCain ML, Parker KK | Advanced functional materials | 26213529 | Adv Funct Mater | 2013 Aug 12 |
| Microfabrication of human organs-on-chips. | Huh D, Kim HJ, Fraser JP, Shea DE, Khan M, Bahinski A, Hamilton GA, Ingber DE | Nature protocols | 24113786 | Nat Protoc | 2013 Nov |
| Informatics and standards for nanomedicine technology. | Thomas DG, Klaessig F, Harper SL, Fritts M, Hoover MD, Gaheen S, Stokes TH, Reznik-Zellen R, Freund ET, Klemm JD, Paik DS, Baker NA | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 21721140 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2011 Sep-Oct |
| Manganese-based MRI contrast agents: past, present and future. | Pan D, Schmieder AH, Wickline SA, Lanza GM | Tetrahedron | 22043109 | Tetrahedron | 2011 Nov 4 |
| Antiangiogenic nanotherapy with lipase-labile Sn-2 fumagillin prodrug. | Pan D, Sanyal N, Schmieder AH, Senpan A, Kim B, Yang X, Hu G, Allen JS, Gross RW, Wickline SA, Lanza GM | Nanomedicine (London, England) | 22709347 | Nanomedicine (Lond) | 2012 Oct |
| Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces. | Pham CT, Mitchell LM, Huang JL, Lubniewski CM, Schall OF, Killgore JK, Pan D, Wickline SA, Lanza GM, Hourcade DE | The Journal of biological chemistry | 21047788 | J Biol Chem | 2011 Jan 7 |
| MR cholangiography demonstrates unsuspected rapid biliary clearance of nanoparticles in rodents: implications for clinical translation. | Bulte JW, Schmieder AH, Keupp J, Caruthers SD, Wickline SA, Lanza GM | Nanomedicine : nanotechnology, biology, and medicine | 24832959 | Nanomedicine | 2014 Oct |
| Improved Coarse-Grained Modeling of Cholesterol-Containing Lipid Bilayers. | Daily MD, Olsen BN, Schlesinger PH, Ory DS, Baker NA | Journal of chemical theory and computation | 24910542 | J Chem Theory Comput | 2014 May 13 |
| Standardizing data. | Baker NA, Klemm JD, Harper SL, Gaheen S, Heiskanen M, Rocca-Serra P, Sansone SA | Nature nanotechnology | 23380926 | Nat Nanotechnol | 2013 Feb |
| Nanotherapeutic approaches for the treatment of rheumatoid arthritis. | Pham CT | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 21837725 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2011 Nov-Dec |
| Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using α(v)β₃-targeted theranostic nanoparticles. | Pan D, Schmieder AH, Wang K, Yang X, Senpan A, Cui G, Killgore K, Kim B, Allen JS, Zhang H, Caruthers SD, Shen B, Wickline SA, Lanza GM | Theranostics | 24723979 | Theranostics | 2014 |
| Molecular imaging with computed tomography. | Lanza GM, Pan D | Contrast media & molecular imaging | 24470289 | Contrast Media Mol Imaging | 2014 Jan-Feb |
| Interaction of melittin peptides with perfluorocarbon nanoemulsion particles. | Lee SJ, Schlesinger PH, Wickline SA, Lanza GM, Baker NA | The journal of physical chemistry. B | 22050303 | J Phys Chem B | 2011 Dec 29 |
| ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format. | Thomas DG, Gaheen S, Harper SL, Fritts M, Klaessig F, Hahn-Dantona E, Paik D, Pan S, Stafford GA, Freund ET, Klemm JD, Baker NA | BMC biotechnology | 23311978 | BMC Biotechnol | 2013 Jan 14 |
| Suppression of inflammation in a mouse model of rheumatoid arthritis using targeted lipase-labile fumagillin prodrug nanoparticles. | Zhou HF, Yan H, Senpan A, Wickline SA, Pan D, Lanza GM, Pham CT | Biomaterials | 22922023 | Biomaterials | 2012 Nov |
| alphaVbeta3-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment. | Zhang R, Pan D, Cai X, Yang X, Senpan A, Allen JS, Lanza GM, Wang LV | Theranostics | 25553103 | Theranostics | 2015 |
| Multicolor computed tomographic molecular imaging with noncrystalline high-metal-density nanobeacons. | Pan D, Schirra CO, Wickline SA, Lanza GM | Contrast media & molecular imaging | 24470291 | Contrast Media Mol Imaging | 2014 Jan-Feb |
| Nanoinformatics workshop report: Current resources, community needs, and the proposal of a collaborative framework for data sharing and information integration. | Harper SL, Hutchison JE, Baker N, Ostraat M, Tinkle S, Steevens J, Hoover MD, Adamick J, Rajan K, Gaheen S, Cohen Y, Nel A, Cachau RE, Tuominen M | Computational science & discovery | 24454543 | Comput Sci Discov | 2013 |
| A strategy for combating melanoma with oncogenic c-Myc inhibitors and targeted nanotherapy. | Pan D, Kim B, Hu G, Gupta DS, Senpan A, Yang X, Schmieder A, Swain C, Wickline SA, Tomasson MH, Lanza GM | Nanomedicine (London, England) | 25600969 | Nanomedicine (Lond) | 2015 Jan |
| Near infrared imaging of EGFR of oral squamous cell carcinoma in mice administered arsenic trioxide. | Zhang L, Wang K, Zhao F, Hu W, Chen J, Lanza GM, Shen B, Zhang B | PloS one | 23029451 | PLoS One | 2012 |
| Second Generation Gold Nanobeacons for Robust K-Edge Imaging with Multi-Energy CT. | Schirra CO, Senpan A, Roessl E, Thran A, Stacy AJ, Wu L, Proska R, Pan D | Journal of materials chemistry | 23185109 | J Mater Chem | 2012 Jan 1 |
| Angiogenesis is required for stress fracture healing in rats. | Tomlinson RE, McKenzie JA, Schmieder AH, Wohl GR, Lanza GM, Silva MJ | Bone | 23044046 | Bone | 2013 Jan |
| An early investigation of ytterbium nanocolloids for selective and quantitative "multicolor" spectral CT imaging. | Pan D, Schirra CO, Senpan A, Schmieder AH, Stacy AJ, Roessl E, Thran A, Wickline SA, Proska R, Lanza GM | ACS nano | 22385324 | ACS Nano | 2012 Apr 24 |
| Characterization of early neovascular response to acute lung ischemia using simultaneous (19)F/ (1)H MR molecular imaging. | Schmieder AH, Wang K, Zhang H, Senpan A, Pan D, Keupp J, Caruthers SD, Wickline SA, Shen B, Wagner EM, Lanza GM | Angiogenesis | 23918207 | Angiogenesis | 2014 Jan |
| A brief account of nanoparticle contrast agents for photoacoustic imaging. | Pan D, Kim B, Wang LV, Lanza GM | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 23983210 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2013 Nov-Dec |
| Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles. | Pham CT, Thomas DG, Beiser J, Mitchell LM, Huang JL, Senpan A, Hu G, Gordon M, Baker NA, Pan D, Lanza GM, Hourcade DE | Nanomedicine : nanotechnology, biology, and medicine | 24211337 | Nanomedicine | 2014 Apr |
| Assessing the barriers to image-guided drug delivery. | Lanza GM, Moonen C, Baker JR Jr, Chang E, Cheng Z, Grodzinski P, Ferrara K, Hynynen K, Kelloff G, Lee YE, Patri AK, Sept D, Schnitzer JE, Wood BJ, Zhang M, Zheng G, Farahani K | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 24339356 | Wiley Interdiscip Rev Nanomed Nanobiotechnol | 2014 Jan-Feb |
| Synergy between surface and core entrapped metals in a mixed manganese-gadolinium nanocolloid affords safer MR imaging of sparse biomarkers. | Wang K, Pan D, Schmieder AH, Senpan A, Hourcade DE, Pham CT, Mitchell LM, Caruthers SD, Cui G, Wickline SA, Shen B, Lanza GM | Nanomedicine : nanotechnology, biology, and medicine | 25652900 | Nanomedicine | 2015 Apr |
| Comparative hazard analysis and toxicological modeling of diverse nanomaterials using the embryonic zebrafish (EZ) metric of toxicity. | Harper B, Thomas D, Chikkagoudar S, Baker N, Tang K, Heredia-Langner A, Lins R, Harper S | Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology | 26069453 | J Nanopart Res | 2015 |
| ICAM-1 and nanomedicine: nature's doorway to the extravascular tissue realm. | Lanza GM | Arteriosclerosis, thrombosis, and vascular biology | 22517363 | Arterioscler Thromb Vasc Biol | 2012 May |
| Simulation of fusion-mediated nanoemulsion interactions with model lipid bilayers. | Lee SJ, Schlesinger PH, Wickline SA, Lanza GM, Baker NA | Soft matter | 22712024 | Soft Matter | 2012 Jan 1 |
| Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence. | Hu L, Chen J, Yang X, Caruthers SD, Lanza GM, Wickline SA | Magnetic resonance in medicine | 22915328 | Magn Reson Med | 2013 Jul |
| Nanoinformatics: developing new computing applications for nanomedicine. | Maojo V, Fritts M, Martin-Sanchez F, De la Iglesia D, Cachau RE, Garcia-Remesal M, Crespo J, Mitchell JA, Anguita A, Baker N, Barreiro JM, Benitez SE, De la Calle G, Facelli JC, Ghazal P, Geissbuhler A, Gonzalez-Nilo F, Graf N, Grangeat P, Hermosilla I, Hussein R, Kern J, Koch S, Legre Y, Lopez-Alonso V, Lopez-Campos G, Milanesi L, Moustakis V, Munteanu C, Otero P, Pazos A, Perez-Rey D, Potamias G, Sanz F, Kulikowski C | Computing in science & engineering | 22942787 | Comput Sci Eng | 2012 Jun 1 |
| Physicochemical signatures of nanoparticle-dependent complement activation. | Thomas DG, Chikkagoudar S, Heredia-Langer A, Tardiff MF, Xu Z, Hourcade DE, Pham CT, Lanza GM, Weinberger KQ, Baker NA | Computational science & discovery | 25254068 | Comput Sci Discov | 2014 Mar 21 |
| Angiogenesis and airway reactivity in asthmatic Brown Norway rats. | Wagner EM, Jenkins J, Schmieder A, Eldridge L, Zhang Q, Moldobaeva A, Zhang H, Allen JS, Yang X, Mitzner W, Keupp J, Caruthers SD, Wickline SA, Lanza GM | Angiogenesis | 25149641 | Angiogenesis | 2015 Jan |
| Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide. | Zhou HF, Yan H, Hu Y, Springer LE, Yang X, Wickline SA, Pan D, Lanza GM, Pham CT | ACS nano | 24941020 | ACS Nano | 2014 Jul 22 |
| Annotating the structure and components of a nanoparticle formulation using computable string expressions. | Thomas DG, Chikkagoudar S, Chappell AR, Baker NA | Proceedings. IEEE International Conference on Bioinformatics and Biomedicine | 24533226 | Proceedings (IEEE Int Conf Bioinformatics Biomed) | 2012 Dec 31 |
| Antagonizing the αv β3 integrin inhibits angiogenesis and impairs woven but not lamellar bone formation induced by mechanical loading. | Tomlinson RE, Schmieder AH, Quirk JD, Lanza GM, Silva MJ | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research | 24644077 | J Bone Miner Res | 2014 Sep |
| Balanced UTE-SSFP for 19F MR imaging of complex spectra. | Goette MJ, Keupp J, Rahmer J, Lanza GM, Wickline SA, Caruthers SD | Magnetic resonance in medicine | 25163853 | Magn Reson Med | 2015 Aug |
