Regulatory Science
Regulatory Science
Program Publications
Publications by Program
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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
| Title | Authors | Journal | PubMedID | Publication Date |
|---|---|---|---|---|
| Transporters in drug-refractory epilepsy: clinical significance. | Marchi, N; Gonzalez-Martinez, J; Nguyen, M-T; Granata, T; Janigro, D | Clinical pharmacology and therapeutics | 20019694 | 2010 Jan |
| Biophysics and dynamics of natural and engineered stem cell microenvironments. | Keung, Albert J; Healy, Kevin E; Kumar, Sanjay; Schaffer, David V | Wiley interdisciplinary reviews. Systems biology and medicine | 20836010 | 2010 Jan-Feb |
| Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of *-catenin signaling. | Cimetta, Elisa; Cannizzaro, Christopher; James, Richard; Biechele, Travis; Moon, Randall T; Elvassore, Nicola; Vunjak-Novakovic, Gordana | Lab on a chip. | 20936235 | 2010 Dec 7; |
| Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces. | Pham, Christine T N; Mitchell, Lynne M; Huang, Jennifer L; Lubniewski, Christopher M; Schall, Otto F; Killgore, J Kendall; Pan, Dipanjan; Wickline, Samuel A; Lanza, Gregory M; Hourcade, Dennis E | The Journal of biological chemistry | 21047788 | 2011 Jan 7 |
| Informatics and standards for nanomedicine technology. | Thomas, Dennis G; Klaessig, Fred; Harper, Stacey L; Fritts, Martin; Hoover, Mark D; Gaheen, Sharon; Stokes, Todd H; Reznik-Zellen, Rebecca; Freund, Elaine T; Klemm, Juli D; Paik, David S; Baker, Nathan A | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 21721140 | 2011 Jun 30 |
| Nanotherapeutic approaches for the treatment of rheumatoid arthritis. | Pham, Christine T N | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. | 21837725 | 2011 Nov-Dec; |
| Manganese-based MRI contrast agents: past, present and future. | Pan, Dipanjan; Schmieder, Anne H; Wickline, Samuel A; Lanza, Gregory M | Tetrahedron. | 22043109 | 2011 Nov 04; |
| Interaction of melittin peptides with perfluorocarbon nanoemulsion particles. | Lee, Sun-Joo; Schlesinger, Paul H; Wickline, Samuel A; Lanza, Gregory M; Baker, Nathan A | The journal of physical chemistry. B | 22050303 | 2011 Dec 29 |
| Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip. | Grosberg, Anna; Alford, Patrick W; McCain, Megan L; Parker, Kevin Kit | Lab on a chip | 22072288 | 2011 Dec 21 |
| An early investigation of ytterbium nanocolloids for selective and quantitative "multicolor" spectral CT imaging. | Pan, Dipanjan; Schirra, Carsten O; Senpan, Angana; Schmieder, Anne H; Stacy, Allen J; Roessl, Ewald; Thran, Axel; Wickline, Samuel A; Proska, Roland; Lanza, Gregory M | ACS nano | 22385324 | 2012 Apr 24 |
| An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project. | Meurer, William J; Lewis, Roger J; Tagle, Danilo; Fetters, Michael D; Legocki, Laurie; Berry, Scott; Connor, Jason; Durkalski, Valerie; Elm, Jordan; Zhao, Wenle; Frederiksen, Shirley; Silbergleit, Robert; Palesch, Yuko; Berry, Donald A; Barsan, William G | Annals of emergency medicine | 22424650 | 2012 Oct |
| ICAM-1 and nanomedicine: nature's doorway to the extravascular tissue realm. | Lanza, Gregory M | Arteriosclerosis, thrombosis, and vascular biology | 22517363 | 2012 May |
| Muscle on a chip: in vitro contractility assays for smooth and striated muscle. | Grosberg, Anna; Nesmith, Alexander P; Goss, Josue A; Brigham, Mark D; McCain, Megan L; Parker, Kevin Kit | Journal of pharmacological and toxicological methods | 22521339 | 2012 May-Jun |
| Effect of insurance status on postacute care among working age stroke survivors. | Skolarus, L E; Meurer, W J; Burke, J F; Prvu Bettger, J; Lisabeth, L D | Neurology | 22551730 | 2012 May 15 |
| Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier. | Janigro, Damir | Epilepsia. | 22612806 | 2012 Jun; |
| Adaptive clinical trials: a partial remedy for the therapeutic misconception? | Meurer, William J; Lewis, Roger J; Berry, Donald A | JAMA : the journal of the American Medical Association | 22692168 | 2012 Jun 13 |
| Antiangiogenic nanotherapy with lipase-labile Sn-2 fumagillin prodrug. | Pan, Dipanjan; Sanyal, Nibedita; Schmieder, Anne H; Senpan, Angana; Kim, Benjamin; Yang, Xiaoxia; Hu, Grace; Allen, John S; Gross, Richard W; Wickline, Samuel A; Lanza, Gregory M | Nanomedicine (London, England) | 22709347 | 2012 Oct |
| Simulation of fusion-mediated nanoemulsion interactions with model lipid bilayers. | Lee, Sun-Joo; Schlesinger, Paul H; Wickline, Samuel A; Lanza, Gregory M; Baker, Nathan A | Soft matter | 22712024 | 2012 Jan 1 |
| The contribution of cellular mechanotransduction to cardiomyocyte form and function. | Sheehy, Sean P; Grosberg, Anna; Parker, Kevin Kit | Biomechanics and modeling in mechanobiology | 22772714 | 2012 Nov |
| A mini-microscope for in situ monitoring of cells. | Kim, Sang Bok; Koo, Kyo-in; Bae, Hojae; Dokmeci, Mehmet R; Hamilton, Geraldine A; Bahinski, Anthony; Kim, Sun Min; Ingber, Donald E; Khademhosseini, Ali | Lab on a chip | 22911426 | 2012 Oct 21 |
| Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence. | Hu, Lingzhi; Chen, Junjie; Yang, Xiaoxia; Caruthers, Shelton D; Lanza, Gregory M; Wickline, Samuel A | Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine | 22915328 | 2012 Aug 22 |
| Suppression of inflammation in a mouse model of rheumatoid arthritis using targeted lipase-labile fumagillin prodrug nanoparticles. | Zhou, Hui-Fang; Yan, Huimin; Senpan, Angana; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T N | Biomaterials | 22922023 | 2012 Nov |
| Nanoinformatics: developing new computing applications for nanomedicine. | Maojo, V; Fritts, M; Martin-Sanchez, F; De la Iglesia, D; Cachau, R E; Garcia-Remesal, M; Crespo, J; Mitchell, J A; Anguita, A; Baker, N; Barreiro, J M; Benitez, S E; De la Calle, G; Facelli, J C; Ghazal, P; Geissbuhler, A; Gonzalez-Nilo, F; Graf, N; Gran | Computing in science & engineering | 22942787 | 2012 Jun 1 |
| Near infrared imaging of EGFR of oral squamous cell carcinoma in mice administered arsenic trioxide. | Zhang, Lingbo; Wang, Kezheng; Zhao, Falin; Hu, Weiping; Chen, Junjie; Lanza, Gregory M; Shen, Baozhong; Zhang, Bin | PloS one | 23029451 | 2012 |
| Angiogenesis is required for stress fracture healing in rats. | Tomlinson, Ryan E; McKenzie, Jennifer A; Schmieder, Anne H; Wohl, Gregory R; Lanza, Gregory M; Silva, Matthew J | Bone | 23044046 | 2013 Jan |
| Bursting drops in solid dielectrics caused by high voltages. | Wang, Qiming; Suo, Zhigang; Zhao, Xuanhe | Nature communications. | 23093194 | 2012; |
| Elucidation of adhesion-dependent spontaneous apoptosis in macrophages using phase separated PEG/polyurethane films. | Zachman, Angela L; Page, Jonathan M; Prabhakar, Gayathri; Guelcher, Scott A; Sung, Hak-Joon | Acta biomaterialia. | 23128157 | 2013 Feb; |
| A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. | Huh, Dongeun; Leslie, Daniel C; Matthews, Benjamin D; Fraser, Jacob P; Jurek, Samuel; Hamilton, Geraldine A; Thorneloe, Kevin S; McAlexander, Michael Allen; Ingber, Donald E | Science translational medicine | 23136042 | 2012 Nov 7 |
| Second Generation Gold Nanobeacons for Robust K-Edge Imaging with Multi-Energy CT. | Schirra, Carsten O; Senpan, Angana; Roessl, Ewald; Thran, Axel; Stacy, Allen J; Wu, Lina; Proska, Roland; Pan, Dipanjan | Journal of materials chemistry. | 23185109 | 2012 Jan 01; |
| Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells. | Cimetta, Elisa; Sirabella, Dario; Yeager, Keith; Davidson, Kathryn; Simon, Joseph; Moon, Randall T; Vunjak-Novakovic, Gordana | Lab on a chip | 23232509 | 2013 Feb 7 |
| The inexorable rise of AKI: can we bend the growth curve? | Siew, Edward D; Himmelfarb, Jonathan | Journal of the American Society of Nephrology : JASN. | 23243210 | 2013 Jan; |
| ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format. | Thomas, Dennis G; Gaheen, Sharon; Harper, Stacey L; Fritts, Martin; Klaessig, Fred; Hahn-Dantona, Elizabeth; Paik, David; Pan, Sue; Stafford, Grace A; Freund, Elaine T; Klemm, Juli D; Baker, Nathan A | BMC biotechnology | 23311978 | 2013 |
| Regenerative medicine in 2012: the coming of age of musculoskeletal tissue engineering. | Tuan, Rocky S | Nature reviews. Rheumatology. | 23321611 | 2013 Feb; |
| Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis. | Campanholle, Gabriela; Ligresti, Giovanni; Gharib, Sina A; Duffield, Jeremy S | American journal of physiology. Cell physiology. | 23325411 | 2013 Apr 1; |
| Modeling boundary conditions for balanced proliferation in metastatic latency. | Taylor, Donald P; Wells, Jakob Z; Savol, Andrej; Chennubhotla, Chakra; Wells, Alan | Clinical cancer research : an official journal of the American Association for Cancer Research | 23329811 | 2013 Mar 1 |
| Multifunctionality and control of the crumpling and unfolding of large-area graphene. | Zang, Jianfeng; Ryu, Seunghwa; Pugno, Nicola; Wang, Qiming; Tu, Qing; Buehler, Markus J; Zhao, Xuanhe | Nature materials. | 23334002 | 2013 Apr; |
| Nonsteady state oxygen transport in engineered tissue: implications for design. | Ehsan, Seema M; George, Steven C | Tissue engineering. Part A. | 23350630 | 2013 Jun; |
| Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes. | Robertson, Claire; Tran, David D; George, Steven C | Stem cells (Dayton, Ohio). | 23355363 | 2013 May; |
| Engineering challenges for instrumenting and controlling integrated organ-on-chip systems. | Wikswo, John P; Block 3rd, Frank E; Cliffel, David E; Goodwin, Cody R; Marasco, Christina C; Markov, Dmitry A; McLean, David L; McLean, John A; McKenzie, Jennifer R; Reiserer, Ronald S; Samson, Philip C; Schaffer, David K; Seale, Kevin T; Sherrod, Stacy D | IEEE transactions on bio-medical engineering | 23380852 | 2013 Mar |
| Standardizing data. | Baker, Nathan A; Klemm, Juli D; Harper, Stacey L; Gaheen, Sharon; Heiskanen, Mervi; Rocca-Serra, Philippe; Sansone, Susanna-Assunta | Nature nanotechnology | 23380926 | 2013 Feb |
| A new dynamic in vitro modular capillaries-venules modular system: cerebrovascular physiology in a box. | Cucullo, Luca; Hossain, Mohammed; Tierney, William; Janigro, Damir | BMC neuroscience. | 23388041 | 2013; |
| Does Systemic Inflammation Play a Role in Pediatric Psychosis? | Falcone, Tatiana; Carlton, Erin; Lee, Catherine; Janigro, Mattia; Fazio, Vince; Forcen, Fernando Espi; Franco, Kathleen; Janigro, Damir | Clinical schizophrenia & related psychoses | 23491967 | 2015 |
| EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury. | Kida, Yujiro; Ieronimakis, Nicholas; Schrimpf, Claudia; Reyes, Morayma; Duffield, Jeremy S | Journal of the American Society of Nephrology : JASN. | 23492730 | 2013 Mar; |
| Poly(?-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells. | Crowder, Spencer W; Liang, Yi; Rath, Rutwik; Park, Andrew M; Maltais, Simon; Pintauro, Peter N; Hofmeister, William; Lim, Chee C; Wang, Xintong; Sung, Hak-Joon | Nanomedicine (London, England). | 23530764 | 2013 Nov; |
| Bioreactor engineering of stem cell environments. | Tandon, Nina; Marolt, Darja; Cimetta, Elisa; Vunjak-Novakovic, Gordana | Biotechnology advances | 23531529 | 2013 Mar 24 |
| Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro. | Nguyen, Duc-Huy T; Stapleton, Sarah C; Yang, Michael T; Cha, Susie S; Choi, Colin K; Galie, Peter A; Chen, Christopher S | Proceedings of the National Academy of Sciences of the United States of America. | 23569284 | 2013 Apr 23; |
| A therapy for liver failure found in the JNK yard. | Willenbring, Holger; Grompe, Markus | Cell. | 23582318 | 2013 Apr 11; |
| Three-dimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells. | Crowder, Spencer W; Prasai, Dhiraj; Rath, Rutwik; Balikov, Daniel A; Bae, Hojae; Bolotin, Kirill I; Sung, Hak-Joon | Nanoscale. | 23592029 | 2013 May 21; |
| Production and assessment of decellularized pig and human lung scaffolds. | Nichols, Joan E; Niles, Jean; Riddle, Michael; Vargas, Gracie; Schilagard, Tuya; Ma, Liang; Edward, Kert; La Francesca, Saverio; Sakamoto, Jason; Vega, Stephanie; Ogadegbe, Marie; Mlcak, Ronald; Deyo, Donald; Woodson, Lee; McQuitty, Christopher; Lick, Sco | Tissue engineering. Part A. | 23638920 | 2013 Sep; |
| Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. | Zhang, Donghui; Shadrin, Ilya Y; Lam, Jason; Xian, Hai-Qian; Snodgrass, H Ralph; Bursac, Nenad | Biomaterials. | 23642535 | 2013 Jul; |
| Mechanistic validation. | Hartung, Thomas; Hoffmann, Sebastian; Stephens, Martin | ALTEX | 23665802 | 2013 |
| Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. | Ma, Xiaocui; Duan, Yuyou; Tschudy-Seney, Benjamin; Roll, Garrett; Behbahan, Iman Saramipoor; Ahuja, Tijess P; Tolstikov, Vladimir; Wang, Charles; McGee, Jeannine; Khoobyari, Shiva; Nolta, Jan A; Willenbring, Holger; Zern, Mark A | Stem cells translational medicine. | 23681950 | 2013 Jun; |
| Engineering skeletal muscle repair. | Juhas, Mark; Bursac, Nenad | Current opinion in biotechnology. | 23711735 | 2013 Oct; |
| Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip. | McCain, Megan L; Sheehy, Sean P; Grosberg, Anna; Goss, Josue A; Parker, Kevin Kit | Proceedings of the National Academy of Sciences of the United States of America. | 23716679 | 2013 Jun 11; |
| Pericytes in kidney fibrosis. | Ren, Shuyu; Duffield, Jeremy S | Current opinion in nephrology and hypertension. | 23722183 | 2013 Jul; |
| A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays. | Hsu, Yu-Hsiang; Moya, Monica L; Hughes, Christopher C W; George, Steven C; Lee, Abraham P | Lab on a chip. | 23723013 | 2013 Aug 7; |
| Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts. | Shi, Mingjian; Majumdar, Devi; Gao, Yandong; Brewer, Bryson M; Goodwin, Cody R; McLean, John A; Li, Deyu; Webb, Donna J | Lab on a chip. | 23736663 | 2013 Aug 7; |
| Changes in macrophage phenotype as the immune response evolves. | Lichtnekert, Julia; Kawakami, Takahisa; Parks, William C; Duffield, Jeremy S | Current opinion in pharmacology. | 23747023 | 2013 Aug; |
| Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. | Christoforou, Nicolas; Liau, Brian; Chakraborty, Syandan; Chellapan, Malathi; Bursac, Nenad; Leong, Kam W | PloS one. | 23785459 | 2013; |
| Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients. | Baker, Brendon M; Trappmann, Britta; Stapleton, Sarah C; Toro, Esteban; Chen, Christopher S | Lab on a chip. | 23787488 | 2013 Aug 21; |
| The Dormancy Dilemma: Quiescence versus Balanced Proliferation. | Wells, Alan; Griffith, Linda; Wells, Jakob Z; Taylor, Donald P | Cancer research | 23794703 | 2013 Jun 21 |
| Microfluidic heart on a chip for higher throughput pharmacological studies. | Agarwal, Ashutosh; Goss, Josue Adrian; Cho, Alexander; McCain, Megan Laura; Parker, Kevin Kit | Lab on a chip | 23807141 | 2013 Aug 13 |
| Scaling and systems biology for integrating multiple organs-on-a-chip. | Wikswo, John P; Curtis, Erica L; Eagleton, Zachary E; Evans, Brian C; Kole, Ayeeshik; Hofmeister, Lucas H; Matloff, William J | Lab on a chip | 23828456 | 2013 Aug 13 |
| Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus. | Connor, Jason T; Elm, Jordan J; Broglio, Kristine R; ESETT and ADAPT-IT Investigators | Journal of clinical epidemiology | 23849147 | 2013 Aug |
| Spinal Cord Injury Neuroprotection and the Promise of Flexible Adaptive Clinical Trials. | Meurer, William J; Barsan, William G | World neurosurgery | 23851207 | 2013 Jul 9 |
| Look back in anger - what clinical studies tell us about preclinical work. | Hartung, Thomas | ALTEX | 23861075 | 2013 |
| Expression and functional relevance of UGT1A4 in a cohort of human drug-resistant epileptic brains. | Ghosh, Chaitali; Hossain, Mohammed; Puvenna, Vikram; Martinez-Gonzalez, Jorge; Alexopolous, Andreas; Janigro, Damir; Marchi, Nicola | Epilepsia. | 23865846 | 2013 Sep; |
| Rat hepatocyte culture model of macrosteatosis: effect of macrosteatosis induction and reversal on viability and liver-specific function. | Nativ, Nir I; Yarmush, Gabriel; Chen, Alvin; Dong, David; Henry, Scot D; Guarrera, James V; Klein, Kenneth M; Maguire, Tim; Schloss, Rene; Berthiaume, Francois; Yarmush, Martin L | Journal of hepatology. | 23872604 | 2013 Dec; |
| Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. | Johnston, S Claiborne; Easton, J Donald; Farrant, Mary; Barsan, William; Battenhouse, Holly; Conwit, Robin; Dillon, Catherine; Elm, Jordan; Lindblad, Anne; Morgenstern, Lewis; Poisson, Sharon N; Palesch, Yuko | International journal of stroke : official journal of the International Stroke Society | 23879752 | 2013 Aug |
| Transplantable liver organoids made from only three ingredients. | Willenbring, Holger; Soto-Gutierrez, Alejandro | Cell stem cell. | 23910079 | 2013 Aug 1; |
| Characterization of early neovascular response to acute lung ischemia using simultaneous (19)F/ (1)H MR molecular imaging. | Schmieder, Anne H; Wang, Kezheng; Zhang, Huiying; Senpan, Angana; Pan, Dipanjan; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Shen, Baozhong; Wagner, Elizabeth M; Lanza, Gregory M | Angiogenesis | 23918207 | 2014 Jan |
| Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. | Hung, Chi; Linn, Geoffrey; Chow, Yu-Hua; Kobayashi, Akio; Mittelsteadt, Kristen; Altemeier, William A; Gharib, Sina A; Schnapp, Lynn M; Duffield, Jeremy S | American journal of respiratory and critical care medicine | 23924232 | 2013 Oct 01 |
| A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells. | Magness, Scott T; Puthoff, Brent J; Crissey, Mary Ann; Dunn, James; Henning, Susan J; Houchen, Courtney; Kaddis, John S; Kuo, Calvin J; Li, Linheng; Lynch, John; Martin, Martin G; May, Randal; Niland, Joyce C; Olack, Barbara; Qian, Dajun; Stelzner, Matthi | American journal of physiology. Gastrointestinal and liver physiology. | 23928185 | 2013 Oct 15; |
| Bioengineering heart tissue for in vitro testing. | Cimetta, Elisa; Godier-Furnemont, Amandine; Vunjak-Novakovic, Gordana | Current opinion in biotechnology | 23932513 | 2013 Aug 6 |
| Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase. | Coulter, Jonathan B; O'Driscoll, Cliona M; Bressler, Joseph P | The Journal of biological chemistry. | 23940045 | 2013 Oct 4; |
| Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. | Hou, Zhonggang; Zhang, Yan; Propson, Nicholas E; Howden, Sara E; Chu, Li-Fang; Sontheimer, Erik J; Thomson, James A | Proceedings of the National Academy of Sciences of the United States of America. | 23940360 | 2013 Sep 24; |
| Clear castable polyurethane elastomer for fabrication of microfluidic devices. | Domansky, Karel; Leslie, Daniel C; McKinney, James; Fraser, Jacob P; Sliz, Josiah D; Hamkins-Indik, Tiama; Hamilton, Geraldine A; Bahinski, Anthony; Ingber, Donald E | Lab on a chip | 23954953 | 2013 Oct 7 |
| Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions. | Kawakami, Takahisa; Lichtnekert, Julia; Thompson, Lucas J; Karna, Prasanthi; Bouabe, Hicham; Hohl, Tobias M; Heinecke, Jay W; Ziegler, Steven F; Nelson, Peter J; Duffield, Jeremy S | Journal of immunology (Baltimore, Md. : 1950) | 23956422 | 2013 Sep 15 |
| A brief account of nanoparticle contrast agents for photoacoustic imaging. | Pan, Dipanjan; Kim, Benjamin; Wang, Lihong V; Lanza, Gregory M | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 23983210 | 2013 Nov-Dec |
| A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches. | Janigro, Damir; Iffland 2nd, Philip H; Marchi, Nicola; Granata, Tiziana | Epilepsia. | 24001067 | 2013 Sep; |
| The established status epilepticus trial 2013. | Bleck, Thomas; Cock, Hannah; Chamberlain, James; Cloyd, James; Connor, Jason; Elm, Jordan; Fountain, Nathan; Jones, Elizabeth; Lowenstein, Daniel; Shinnar, Shlomo; Silbergleit, Robert; Treiman, David; Trinka, Eugen; Kapur, Jaideep | Epilepsia | 24001084 | 2013 Sep |
| Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix. | Yang, Guang; Rothrauff, Benjamin B; Lin, Hang; Gottardi, Riccardo; Alexander, Peter G; Tuan, Rocky S | Biomaterials. | 24044998 | 2013 Dec; |
| Variation in diffusion of gases through PDMS due to plasma surface treatment and storage conditions. | Markov, Dmitry A; Lillie, Elizabeth M; Garbett, Shawn P; McCawley, Lisa J | Biomedical microdevices. | 24065585 | 2014 Feb; |
| Femtosecond laser-patterned nanopore arrays for surface-mediated peptide treatment. | Zachman, Angela L; Hofmeister, Lucas H; Costa, Lino; Boire, Timothy C; Hwang, Yu-Shik; Hofmeister, William H; Sung, Hak-Joon | Nanomedicine : nanotechnology, biology, and medicine | 24090768 | 2014 Jan |
| Portable bioreactor for perfusion and electrical stimulation of engineered cardiac tissue. | Tandon, Nina; Taubman, Alanna; Cimetta, Elisa; Saccenti, Laetitia; Vunjak-Novakovic, Gordana | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. | 24111161 | 2013; |
| Microfabrication of human organs-on-chips. | Huh, Dongeun; Kim, Hyun Jung; Fraser, Jacob P; Shea, Daniel E; Khan, Mohammed; Bahinski, Anthony; Hamilton, Geraldine A; Ingber, Donald E | Nature protocols | 24113786 | 2013 Nov |
| Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport. | Yeung, Catherine K; Shen, Danny D; Thummel, Kenneth E; Himmelfarb, Jonathan | Kidney international | 24132209 | 2014 Mar |
| Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers. | Fernandez, Cristina E; Obi-onuoha, Izundu C; Wallace, Charles S; Satterwhite, Lisa L; Truskey, George A; Reichert, William M | Acta biomaterialia | 24140604 | 2014 Feb |
| Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs). | Itoh, Munenari; Umegaki-Arao, Noriko; Guo, Zongyou; Liu, Liang; Higgins, Claire A; Christiano, Angela M | PloS one. | 24147053 | 2013; |
| Microfluidic device to culture 3D in vitro human capillary networks. | Moya, Monica L; Alonzo, Luis F; George, Steven C | Methods in molecular biology (Clifton, N.J.). | 24155229 | 2014; |
| Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption. | Singh, Varsha; Yang, Jianbo; Chen, Tiane-e; Zachos, Nicholas C; Kovbasnjuk, Olga; Verkman, Alan S; Donowitz, Mark | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. | 24184676 | 2014 Jan; |
| Development of a new method for the isolation and culture of pulmonary arterial endothelial cells from rat pulmonary arteries. | Peng, Gongyong; Wen, Xing; Shi, Yu; Jiang, Yongliang; Hu, Guoping; Zhou, Yumin; Ran, Pixin | Journal of vascular research. | 24192526 | 2013; |
| Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles. | Pham, Christine T N; Thomas, Dennis G; Beiser, Julia; Mitchell, Lynne M; Huang, Jennifer L; Senpan, Angana; Hu, Grace; Gordon, Mae; Baker, Nathan A; Pan, Dipanjan; Lanza, Gregory M; Hourcade, Dennis E | Nanomedicine : nanotechnology, biology, and medicine | 24211337 | 2013 Nov 8 |
| New immunological approaches in treating and diagnosing CNS diseases. | Guo, Kathy; Janigro, Damir | Pharmaceutical patent analyst | 24237062 | 2013 May |
| Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion. | Grahovac, Jelena; Wells, Alan | Laboratory investigation; a journal of technical methods and pathology | 24247562 | 2014 Jan |
| Three-dimensional filamentous human diseased cardiac tissue model. | Ma, Zhen; Koo, Sangmo; Finnegan, Micaela A; Loskill, Peter; Huebsch, Nathaniel; Marks, Natalie C; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin E | Biomaterials | 24268663 | 2014 Feb |
| Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems. | Hong, Sungmin; Jung, Youngmee; Yen, Ringo; Chan, Hon Fai; Leong, Kam W; Truskey, George A; Zhao, Xuanhe | Lab on a chip. | 24310854 | 2014 Feb 7; |
| Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients. | McLaughlin, Bethann; Gidday, Jeff M | Translational stroke research | 24323191 | 2013 Feb |
| Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays. | Nguyen, Eric H; Zanotelli, Matthew R; Schwartz, Michael P; Murphy, William L | Biomaterials | 24332391 | 2014 Feb |
| Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. | Cheng, Cindy S; El-Abd, Yasser; Bui, Khanh; Hyun, Young-Eun; Hughes, Rebecca Harbuck; Kraus, William E; Truskey, George A | American journal of physiology. Cell physiology | 24336652 | 2014 Feb 15 |
| Harnessing localized ridges for high-aspect-ratio hierarchical patterns with dynamic tunability and multifunctionality. | Cao, Changyong; Chan, Hon Fai; Zang, Jianfeng; Leong, Kam W; Zhao, Xuanhe | Advanced materials (Deerfield Beach, Fla.) | 24339233 | 2014 Mar 19 |
| Assessing the barriers to image-guided drug delivery. | Lanza, Gregory M; Moonen, Chrit; Baker Jr, James R; Chang, Esther; Cheng, Zheng; Grodzinski, Piotr; Ferrara, Katherine; Hynynen, Kullervo; Kelloff, Gary; Lee, Yong-Eun Koo; Patri, Anil K; Sept, David; Schnitzer, Jan E; Wood, Bradford J; Zhang, Miqin; Zhen | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 24339356 | 2014 Jan-Feb |
| Inflammatory pathways of seizure disorders. | Marchi, Nicola; Granata, Tiziana; Janigro, Damir | Trends in neurosciences. | 24355813 | 2014 Feb; |
| Physiologically relevant organs on chips. | Yum, Kyungsuk; Hong, Soon Gweon; Healy, Kevin E; Lee, Luke P | Biotechnology journal. | 24357624 | 2014 Jan; |
| Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles. | Rangarajan, Swathi; Madden, Lauran; Bursac, Nenad | Annals of biomedical engineering. | 24366526 | 2014 Jul; |
| Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy. | Li, Fengqiang; Xu, Ting; Nguyen, Duc-Huy T; Huang, Xiaolei; Chen, Christopher S; Zhou, Chao | Journal of biomedical optics. | 24395588 | 2014 Jan; |
| How multi-organ microdevices can help foster drug development. | Esch, Mandy B; Smith, Alec S T; Prot, Jean-Matthieu; Oleaga, Carlota; Hickman, James J; Shuler, Michael L | Advanced drug delivery reviews. | 24412641 | 2014 Apr; |
| The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine. | Martins, Ana M; Vunjak-Novakovic, Gordana; Reis, Rui L | Stem cell reviews | 24425421 | 2014 Apr |
| Mapping the human toxome by systems toxicology. | Bouhifd, Mounir; Hogberg, Helena T; Kleensang, Andre; Maertens, Alexandra; Zhao, Liang; Hartung, Thomas | Basic & clinical pharmacology & toxicology | 24443875 | 2014 Jul |
| Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer. | May, Jody C; Goodwin, Cody R; Lareau, Nichole M; Leaptrot, Katrina L; Morris, Caleb B; Kurulugama, Ruwan T; Mordehai, Alex; Klein, Christian; Barry, William; Darland, Ed; Overney, Gregor; Imatani, Kenneth; Stafford, George C; Fjeldsted, John C; McLean, Jo | Analytical chemistry. | 24446877 | 2014 Feb 18; |
| Nanoinformatics workshop report: Current resources, community needs, and the proposal of a collaborative framework for data sharing and information integration. | Harper, Stacey L; Hutchison, James E; Baker, Nathan; Ostraat, Michele; Tinkle, Sally; Steevens, Jeffrey; Hoover, Mark D; Adamick, Jessica; Rajan, Krishna; Gaheen, Sharon; Cohen, Yoram; Nel, Andre; Cachau, Raul E; Tuominen, Mark | Computational science & discovery | 24454543 | 2013 |
| Molecular imaging with computed tomography. | Lanza, Gregory M; Pan, Dipanjan | Contrast media & molecular imaging | 24470289 | 2014 Jan-Feb |
| Multicolor computed tomographic molecular imaging with noncrystalline high-metal-density nanobeacons. | Pan, Dipanjan; Schirra, Carsten O; Wickline, Samuel A; Lanza, Gregory M | Contrast media & molecular imaging | 24470291 | 2014 Jan-Feb |
| Physical influences on stem cells. | Vunjak-Novakovic, Gordana | Stem cell research & therapy. | 24476419 | 2013; |
| Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues. | Li, Cheri Yingjie; Stevens, Kelly R; Schwartz, Robert E; Alejandro, Brian Steven; Huang, Joanne H; Bhatia, Sangeeta N | Tissue engineering. Part A | 24498910 | 2014 Feb 5 |
| Biological and engineering design considerations for vascular tissue engineered blood vessels (TEBVs). | Fernandez, Cristina E; Achneck, Hardean E; Reichert, William M; Truskey, George A | Current opinion in chemical engineering. | 24511460 | 2014 Feb 1; |
| Annotating the structure and components of a nanoparticle formulation using computable string expressions. | Thomas, Dennis G; Chikkagoudar, Satish; Chappell, Alan R; Baker, Nathan A | Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. | 24533226 | 2012 Dec 31; |
| Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system. | Kelly, Edward J; Wang, Zhican; Voellinger, Jenna L; Yeung, Cathy K; Shen, Danny D; Thummel, Kenneth E; Zheng, Ying; Ligresti, Giovanni; Eaton, David L; Muczynski, Kimberly A; Duffield, Jeremy S; Neumann, Thomas; Tourovskaia, Anna; Fauver, Mark; Kramer, Gr | Stem cell research & therapy. | 24564863 | 2013; |
| Neurovascular unit on a chip: implications for translational applications. | Alcendor, Donald J; Block 3rd, Frank E; Cliffel, David E; Daniels, John Scott; Ellacott, Kate L J; Goodwin, Cody R; Hofmeister, Lucas H; Li, Deyu; Markov, Dmitry A; May, Jody C; McCawley, Lisa J; McLaughlin, BethAnn; McLean, John A; Niswender, Kevin D; Pe | Stem cell research & therapy. | 24564885 | 2013; |
| Building a microphysiological skin model from induced pluripotent stem cells. | Guo, Zongyou; Higgins, Claire A; Gillette, Brian M; Itoh, Munenari; Umegaki, Noriko; Gledhill, Karl; Sia, Samuel K; Christiano, Angela M | Stem cell research & therapy. | 24564920 | 2013; |
| Human enteroids: preclinical models of non-inflammatory diarrhea. | Kovbasnjuk, Olga; Zachos, Nicholas C; In, Julie; Foulke-Abel, Jennifer; Ettayebi, Khalil; Hyser, Joseph M; Broughman, James R; Zeng, Xi-Lei; Middendorp, Sabine; de Jonge, Hugo R; Estes, Mary K; Donowitz, Mark | Stem cell research & therapy. | 24564938 | 2013; |
| Toward a 3D model of human brain development for studying gene/environment interactions. | Hogberg, Helena T; Bressler, Joseph; Christian, Kimberly M; Harris, Georgina; Makri, Georgia; O'Driscoll, Cliona; Pamies, David; Smirnova, Lena; Wen, Zhexing; Hartung, Thomas | Stem cell research & therapy. | 24564953 | 2013; |
| Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. | Hartman, Kira G; Bortner, James D; Falk, Gary W; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John P | Stem cell research & therapy. | 24564965 | 2013; |
| Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis. | Lozito, Thomas P; Alexander, Peter G; Lin, Hang; Gottardi, Riccardo; Cheng, Anthony Wai-Ming; Tuan, Rocky S | Stem cell research & therapy. | 24564995 | 2013; |
| Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology. | Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Cortiella, Joaquin | Stem cell research & therapy. | 24565038 | 2013; |
| HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease. | Vunjak-Novakovic, Gordana; Bhatia, Sangeeta; Chen, Christopher; Hirschi, Karen | Stem cell research & therapy | 24565063 | 2013 |
| Microphysiological systems and low-cost microfluidic platform with analytics. | Smith, Alec S T; Long, Christopher J; Berry, Bonnie J; McAleer, Christopher; Stancescu, Maria; Molnar, Peter; Miller, Paula G; Esch, Mandy B; Prot, Jean-Matthieu; Hickman, James J; Shuler, Michael L | Stem cell research & therapy. | 24565109 | 2013; |
| Building additional complexity to in vitro-derived intestinal tissues. | Brugmann, Samantha A; Wells, James M | Stem cell research & therapy. | 24565179 | 2013; |
| Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing. | Truskey, George A; Achneck, Hardean E; Bursac, Nenad; Chan, Hon; Cheng, Cindy S; Fernandez, Cristina; Hong, Sungmin; Jung, Youngmee; Koves, Tim; Kraus, William E; Leong, Kam; Madden, Lauran; Reichert, William M; Zhao, Xuanhe | Stem cell research & therapy. | 24565225 | 2013; |
| All-human microphysical model of metastasis therapy. | Wheeler, Sarah E; Borenstein, Jeffrey T; Clark, Amanda M; Ebrahimkhani, Mohammad R; Fox, Ira J; Griffith, Linda; Inman, Walker; Lauffenburger, Douglas; Nguyen, Transon; Pillai, Venkateswaran C; Prantil-Baun, Rachelle; Stolz, Donna B; Taylor, Donald; Ulric | Stem cell research & therapy. | 24565274 | 2013; |
| A human pluripotent stem cell platform for assessing developmental neural toxicity screening. | Hou, Zhonggang; Zhang, Jue; Schwartz, Michael P; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James A | Stem cell research & therapy. | 24565336 | 2013; |
| Recreating the female reproductive tract in vitro using iPSC technology in a linked microfluidics environment. | Laronda, Monica M; Burdette, Joanna E; Kim, J; Woodruff, Teresa K | Stem cell research & therapy | 24565375 | 2013 |
| Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development. | Mathur, Anurag; Loskill, Peter; Hong, Soongweon; Lee, Jae; Marcus, Sivan G; Dumont, Laure; Conklin, Bruce R; Willenbring, Holger; Lee, Luke P; Healy, Kevin E | Stem cell research & therapy. | 24565415 | 2013; |
| An integrated in vitro model of perfused tumor and cardiac tissue. | Moya, Monica; Tran, David; George, Steven C | Stem cell research & therapy. | 24565445 | 2013; |
| Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans. | Bhushan, Abhinav; Senutovitch, Nina; Bale, Shyam S; McCarty, William J; Hegde, Manjunath; Jindal, Rohit; Golberg, Inna; Berk Usta, O; Yarmush, Martin L; Vernetti, Lawrence; Gough, Albert; Bakan, Ahmet; Shun, Tong Ying; DeBiasio, Richard; Lansing Taylor, D | Stem cell research & therapy. | 24565476 | 2013; |
| Mouse liver repopulation with hepatocytes generated from human fibroblasts. | Zhu, Saiyong; Rezvani, Milad; Harbell, Jack; Mattis, Aras N; Wolfe, Alan R; Benet, Leslie Z; Willenbring, Holger; Ding, Sheng | Nature. | 24572354 | 2014 Apr 3; |
| Three-dimensional paper-based model for cardiac ischemia. | Mosadegh, Bobak; Dabiri, Borna E; Lockett, Matthew R; Derda, Ratmir; Campbell, Patrick; Parker, Kevin Kit; Whitesides, George M | Advanced healthcare materials. | 24574054 | 2014 Jul; |
| Cartilage tissue engineering application of injectable gelatin hydrogel with in situ visible-light-activated gelation capability in both air and aqueous solution. | Lin, Hang; Cheng, Anthony Wai-Ming; Alexander, Peter G; Beck, Angela M; Tuan, Rocky S | Tissue engineering. Part A. | 24575844 | 2014 Sep; |
| Cancer Stem Cells under Hypoxia as a Chemoresistance Factor in Breast and Brain. | Crowder, Spencer W; Balikov, Daniel A; Hwang, Yu-Shik; Sung, Hak-Joon | Current pathobiology reports. | 24587979 | 2014 Mar; |
| Myocardial tissue engineering: in vitro models. | Vunjak Novakovic, Gordana; Eschenhagen, Thomas; Mummery, Christine | Cold Spring Harbor perspectives in medicine. | 24591534 | 2014 Mar; |
| Bioreactor technologies to support liver function in vitro. | Ebrahimkhani, Mohammad R; Neiman, Jaclyn A Shepard; Raredon, Micha Sam B; Hughes, David J; Griffith, Linda G | Advanced drug delivery reviews | 24607703 | 2014 Apr |
| Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition. | Taylor, Donald P; Clark, Amanda; Wheeler, Sarah; Wells, Alan | Breast cancer research and treatment | 24610032 | 2014 Apr |
| The mitogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase (ERK) are involved in hepatocyte-mediated phenotypic switching in prostate cancer cells. | Ma, Bo; Wells, Alan | The Journal of biological chemistry. | 24619413 | 2014 Apr 18; |
| Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor. | Diederichs, Solvig; Tuan, Rocky S | Stem cells and development. | 24625206 | 2014 Jul 15; |
| Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening. | Zhao, Ruogang; Chen, Christopher S; Reich, Daniel H | Biomaterials. | 24630092 | 2014 Jun; |
| Antagonizing the *v *3 integrin inhibits angiogenesis and impairs woven but not lamellar bone formation induced by mechanical loading. | Tomlinson, Ryan E; Schmieder, Anne H; Quirk, James D; Lanza, Gregory M; Silva, Matthew J | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. | 24644077 | 2014 Sep; |
| Engineering Liver. | Griffith, Linda G; Wells, Alan; Stolz, Donna Beer | Hepatology (Baltimore, Md.) | 24668880 | 2014 Mar 26 |
| Quality metrics for stem cell-derived cardiac myocytes. | Sheehy, Sean P; Pasqualini, Francesco; Grosberg, Anna; Park, Sung Jin; Aratyn-Schaus, Yvonne; Parker, Kevin Kit | Stem cell reports. | 24672752 | 2014 Mar 11; |
| Structural characterization of methylenedianiline regioisomers by ion mobility-mass spectrometry, tandem mass spectrometry, and computational strategies: I. Electrospray spectra of 2-ring isomers. | Forsythe, Jay G; Stow, Sarah M; Nefzger, Hartmut; Kwiecien, Nicholas W; May, Jody C; McLean, John A; Hercules, David M | Analytical chemistry. | 24678803 | 2014 May 6; |
| Matrix elasticity regulates the optimal cardiac myocyte shape for contractility. | McCain, Megan L; Yuan, Hongyan; Pasqualini, Francesco S; Campbell, Patrick H; Parker, Kevin Kit | American journal of physiology. Heart and circulatory physiology. | 24682394 | 2014 Jun 1; |
| Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities. | Smirnova, Lena; Hogberg, Helena T; Leist, Marcel; Hartung, Thomas | ALTEX | 24687333 | 2014 |
| The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. | Kulangara, Karina; Adler, Andrew F; Wang, Hong; Chellappan, Malathi; Hammett, Ellen; Yasuda, Ryohei; Leong, Kam W | Biomaterials. | 24709523 | 2014 Jul; |
| Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract. | Foulke-Abel, Jennifer; In, Julie; Kovbasnjuk, Olga; Zachos, Nicholas C; Ettayebi, Khalil; Blutt, Sarah E; Hyser, Joseph M; Zeng, Xi-Lei; Crawford, Sue E; Broughman, James R; Estes, Mary K; Donowitz, Mark | Experimental biology and medicine (Maywood, N.J.). | 24719375 | 2014 Sep; |
| 3D - a new dimension of in vitro research. | Hartung, Thomas | Advanced drug delivery reviews. | 24721291 | 2014 Apr; |
| Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using *(v)*ýýý-targeted theranostic nanoparticles. | Pan, Dipanjan; Schmieder, Anne H; Wang, Kezheng; Yang, Xiaoxia; Senpan, Angana; Cui, Grace; Killgore, Kendall; Kim, Benjamin; Allen, John S; Zhang, Huiying; Caruthers, Shelton D; Shen, Baozhong; Wickline, Samuel A; Lanza, Gregory M | Theranostics | 24723979 | 2014 |
| Integrating in vitro organ-specific function with the microcirculation. | Moya, Monica L; George, Steven C | Current opinion in chemical engineering. | 24729953 | 2014 Feb 1; |
| Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues. | McCain, Megan L; Agarwal, Ashutosh; Nesmith, Haley W; Nesmith, Alexander P; Parker, Kevin Kit | Biomaterials. | 24731714 | 2014 Jul; |
| Microscale technologies for regulating human stem cell differentiation. | Cimetta, Elisa; Vunjak-Novakovic, Gordana | Experimental biology and medicine (Maywood, N.J.). | 24737735 | 2014 Sep; |
| Microphysiological modeling of the reproductive tract: A fertile endeavor. | Eddie, Sharon L; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna E | Experimental biology and medicine (Maywood, N.J.) | 24737736 | 2014 Apr 15 |
| A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening. | Heylman, Christopher; Sobrino, Agua; Shirure, Venktesh S; Hughes, Christopher Cw; George, Steven C | Experimental biology and medicine (Maywood, N.J.). | 24740872 | 2014 Sep; |
| Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKC? signaling. | Cha, Boyoung; Chen, Tiane; Sarker, Rafiquel; Yang, Jianbo; Raben, Daniel; Tse, C Ming; Kovbasnjuk, Olga; Donowitz, Mark | American journal of physiology. Cell physiology. | 24760985 | 2014 Jul 1; |
| A three-dimensional in vitro model of tumor cell intravasation. | Ehsan, Seema M; Welch-Reardon, Katrina M; Waterman, Marian L; Hughes, Christopher C W; George, Steven C | Integrative biology : quantitative biosciences from nano to macro. | 24763498 | 2014 Jun; |
| In vitro platforms for evaluating liver toxicity. | Bale, Shyam Sundhar; Vernetti, Lawrence; Senutovitch, Nina; Jindal, Rohit; Hegde, Manjunath; Gough, Albert; McCarty, William J; Bakan, Ahmet; Bhushan, Abhinav; Shun, Tong Y; Golberg, Inna; DeBiasio, Richard; Usta, O Berk; Taylor, D Lansing; Yarmush, Marti | Experimental biology and medicine (Maywood, N.J.). | 24764241 | 2014 Sep; |
| Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research. | Abrams, Julian A; Appelman, Henry D; Beer, David G; Berry, Lynne D; Chak, Amitabh; Falk, Gary W; Fitzgerald, Rebecca C; Ginsberg, Gregory G; Grady, William M; Joshi, Bishnu P; Lynch, John P; Markowitz, Sanford; Richmond, Ellen S; Rustgi, Anil K; Seibel, E | Gastroenterology. | 24768332 | 2014 Jun; |
| Dynamic interplay of flow and collagen stabilizes primary hepatocytes culture in a microfluidic platform. | Hegde, Manjunath; Jindal, Rohit; Bhushan, Abhinav; Bale, Shyam Sundhar; McCarty, William J; Golberg, Inna; Usta, O Berk; Yarmush, Martin L | Lab on a chip. | 24770663 | 2014 Jun 21; |
| Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems. | Hartman, Kira G; Bortner Jr, James D; Falk, Gary W; Ginsberg, Gregory G; Jhala, Nirag; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John P | Experimental biology and medicine (Maywood, N.J.). | 24781339 | 2014 Sep; |
| Approaches to in vitro tissue regeneration with application for human disease modeling and drug development. | Ebrahimkhani, Mohammad R; Young, Carissa L; Lauffenburger, Douglas A; Griffith, Linda G; Borenstein, Jeffrey T | Drug discovery today | 24793141 | 2014 Jun |
| Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits. | Puvenna, Vikram; Brennan, Chanda; Shaw, Gerald; Yang, Cui; Marchi, Nicola; Bazarian, Jeffrey J; Merchant-Borna, Kian; Janigro, Damir | PloS one. | 24806476 | 2014; |
| Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. | Wang, Gang; McCain, Megan L; Yang, Luhan; He, Aibin; Pasqualini, Francesco Silvio; Agarwal, Ashutosh; Yuan, Hongyan; Jiang, Dawei; Zhang, Donghui; Zangi, Lior; Geva, Judith; Roberts, Amy E; Ma, Qing; Ding, Jian; Chen, Jinghai; Wang, Da-Zhi; Li, Kai; Wang, | Nature medicine. | 24813252 | 2014 Jun; |
| Materials innovation for co-delivery of diverse therapeutic cargos. | Godsey, Megan E; Suryaprakash, Smruthi; Leong, Kam W | RSC advances. | 24818000 | 2013 Dec 21; |
| Polymeric stent materials dysregulate macrophage and endothelial cell functions: implications for coronary artery stent. | Wang, Xintong; Zachman, Angela L; Chun, Young Wook; Shen, Fang-Wen; Hwang, Yu-Shik; Sung, Hak-Joon | International journal of cardiology. | 24820736 | 2014 Jul 1; |
| A microphysiological system model of therapy for liver micrometastases. | Clark, Amanda M; Wheeler, Sarah E; Taylor, Donald P; Pillai, Venkateswaran C; Young, Carissa L; Prantil-Baun, Rachelle; Nguyen, Transon; Stolz, Donna B; Borenstein, Jeffrey T; Lauffenburger, Douglas A; Venkataramanan, Raman; Griffith, Linda G; Wells, Alan | Experimental biology and medicine (Maywood, N.J.). | 24821820 | 2014 Sep; |
| Approaching the in vitro clinical trial: engineering organs on chips. | Capulli, A K; Tian, K; Mehandru, N; Bukhta, A; Choudhury, S F; Suchyta, M; Parker, K K | Lab on a chip. | 24828385 | 2014 Sep 7; |
| Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1?. | Lin, Hang; Lozito, Thomas P; Alexander, Peter G; Gottardi, Riccardo; Tuan, Rocky S | Molecular pharmaceutics. | 24830762 | 2014 Jul 7; |
| MR cholangiography demonstrates unsuspected rapid biliary clearance of nanoparticles in rodents: implications for clinical translation. | Bulte, Jeff W M; Schmieder, Anne H; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory M | Nanomedicine : nanotechnology, biology, and medicine. | 24832959 | 2014 Oct; |
| Multi-scale multi-mechanism design of tough hydrogels: building dissipation into stretchy networks. | Zhao, Xuanhe | Soft matter. | 24834901 | 2014 Feb 7; |
| Intracerebral hemorrhage mortality is not changing despite declining incidence. | Zahuranec, Darin B; Lisabeth, Lynda D; Sanchez, Brisa N; Smith, Melinda A; Brown, Devin L; Garcia, Nelda M; Skolarus, Lesli E; Meurer, William J; Burke, James F; Adelman, Eric E; Morgenstern, Lewis B | Neurology | 24838789 | 2014 Jun 17 |
| Fluid shear stress threshold regulates angiogenic sprouting. | Galie, Peter A; Nguyen, Duc-Huy T; Choi, Colin K; Cohen, Daniel M; Janmey, Paul A; Chen, Christopher S | Proceedings of the National Academy of Sciences of the United States of America | 24843171 | 2014 Jun 3 |
| Ovarian cancer in endometriosis: clinical and molecular aspects. | Lyttle, B; Bernardi, L; Pavone, M E | Minerva ginecologica | 24848074 | 2014 Apr |
| Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury. | Chen, Yi-Ting; Chang, Yu-Ting; Pan, Szu-Yu; Chou, Yu-Hsiang; Chang, Fan-Chi; Yeh, Pei-Ying; Liu, Yuan-Hung; Chiang, Wen-Chih; Chen, Yung-Ming; Wu, Kwan-Dun; Tsai, Tun-Jun; Duffield, Jeremy S; Lin, Shuei-Liong | Journal of the American Society of Nephrology : JASN | 24854266 | 2014 Dec |
| Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. | Evans, J Corey; Hines, Kelly M; Forsythe, Jay G; Erdogan, Begum; Shi, Mingjian; Hill, Salisha; Rose, Kristie L; McLean, John A; Webb, Donna J | Journal of proteome research. | 24874604 | 2014 Jul 3; |
| Cellular and molecular mechanisms in kidney fibrosis. | Duffield, Jeremy S | The Journal of clinical investigation | 24892703 | 2014 Jun |
| Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems. | Marasco, Christina C; Goodwin, Cody R; Winder, Danny G; Schramm-Sapyta, Nicole L; McLean, John A; Wikswo, John P | Experimental biology and medicine (Maywood, N.J.). | 24903164 | 2014 Nov; |
| Induced pluripotent stem cells for regenerative medicine. | Hirschi, Karen K; Li, Song; Roy, Krishnendu | Annual review of biomedical engineering. | 24905879 | 2014 Jul 11; |
| A multiplexed chip-based assay system for investigating the functional development of human skeletal myotubes in vitro. | Smith, A S T; Long, C J; Pirozzi, K; Najjar, S; McAleer, C; Vandenburgh, H H; Hickman, J J | Journal of biotechnology. | 24909944 | 2014 Sep 20; |
| Improved Coarse-Grained Modeling of Cholesterol-Containing Lipid Bilayers. | Daily, Michael D; Olsen, Brett N; Schlesinger, Paul H; Ory, Daniel S; Baker, Nathan A | Journal of chemical theory and computation. | 24910542 | 2014 May 13; |
| Biological and medical applications of a brain-on-a-chip. | Pamies, David; Hartung, Thomas; Hogberg, Helena T | Experimental biology and medicine (Maywood, N.J.). | 24912505 | 2014 Sep; |
| Physiology and metabolism of tissue-engineered skeletal muscle. | Cheng, Cindy S; Davis, Brittany N J; Madden, Lauran; Bursac, Nenad; Truskey, George A | Experimental biology and medicine (Maywood, N.J.). | 24912506 | 2014 Sep; |
| A novel ultrathin collagen nanolayer assembly for 3-D microtissue engineering: Layer-by-layer collagen deposition for long-term stable microfluidic hepatocyte culture. | McCarty, William J; Usta, O Berk; Luitje, Martha; Bale, Shyam Sundhar; Bhushan, Abhinav; Hegde, Manjunath; Golberg, Inna; Jindal, Rohit; Yarmush, Martin L | Technology. | 24932459 | 2014 Mar; |
| Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide. | Zhou, Hui-fang; Yan, Huimin; Hu, Ying; Springer, Luke E; Yang, Xiaoxia; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T N | ACS nano | 24941020 | 2014 Jul 22 |
| Challenges and promises in modeling dermatologic disorders with bioengineered skin. | Eungdamrong, Narat J; Higgins, Claire; Guo, Zongyou; Lee, Wen-Han; Gillette, Brian; Sia, Samuel; Christiano, Angela M | Experimental biology and medicine (Maywood, N.J.). | 24951469 | 2014 Sep; |
| Using physiologically-based pharmacokinetic-guided ''body-on-a-chip'' systems to predict mammalian response to drug and chemical exposure. | Sung, Jong Hwan; Srinivasan, Balaji; Esch, Mandy Brigitte; McLamb, William T; Bernabini, Catia; Shuler, Michael L; Hickman, James J | Experimental biology and medicine (Maywood, N.J.). | 24951471 | 2014 Sep; |
| Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use. | Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Argueta, Lissenya B; Eastaway, Adriene; Cortiella, Joaquin | Experimental biology and medicine (Maywood, N.J.). | 24962174 | 2014 Sep; |
| Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury. | Esch, Mandy B; Mahler, Gretchen J; Stokol, Tracy; Shuler, Michael L | Lab on a chip. | 24970651 | 2014 Aug 21; |
| Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases. | Alexander, Peter G; Gottardi, Riccardo; Lin, Hang; Lozito, Thomas P; Tuan, Rocky S | Experimental biology and medicine (Maywood, N.J.). | 24994814 | 2014 Sep; |
| What non-neuronal mechanisms should be studied to understand epileptic seizures? | Janigro, Damir; Walker, Matthew C | Advances in experimental medicine and biology | 25012382 | 2014 |
| State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. | Alépée, Natalie; Bahinski, Anthony; Daneshian, Mardas; De Wever, Bart; Fritsche, Ellen; Goldberg, Alan; Hansmann, Jan; Hartung, Thomas; Haycock, John; Hogberg, Helena; Hoelting, Lisa; Kelm, Jens M; Kadereit, Suzanne; McVey, Emily; Landsiedel, Robert; Leis | ALTEX. | 25027500 | 2014; |
| Tissue-engineered microenvironment systems for modeling human vasculature. | Tourovskaia, Anna; Fauver, Mark; Kramer, Gregory; Simonson, Sara; Neumann, Thomas | Experimental biology and medicine (Maywood, N.J.). | 25030480 | 2014 Sep; |
| Cell and tissue engineering for liver disease. | Bhatia, Sangeeta N; Underhill, Gregory H; Zaret, Kenneth S; Fox, Ira J | Science translational medicine | 25031271 | 2014 Jul 16 |
| Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery. | Gough, Albert H; Chen, Ning; Shun, Tong Ying; Lezon, Timothy R; Boltz, Robert C; Reese, Celeste E; Wagner, Jacob; Vernetti, Lawrence A; Grandis, Jennifer R; Lee, Adrian V; Stern, Andrew M; Schurdak, Mark E; Taylor, D Lansing | PloS one. | 25036749 | 2014; |
| Developing microphysiological systems for use as regulatory tools--challenges and opportunities. | Andersen, Melvin E; Betts, Kellyn; Dragan, Yvonne; Fitzpatrick, Suzanne; Goodman, Jesse L; Hartung, Thomas; Himmelfarb, Jonathan; Ingber, Donald E; Jacobs, Abigail; Kavlock, Robert; Kolaja, Kyle; Stevens, James L; Tagle, Dan; Lansing Taylor, D; Throckmort | ALTEX. | 25061900 | 2014; |
| Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes. | Freytes, Donald O; O'Neill, John D; Duan-Arnold, Yi; Wrona, Emily A; Vunjak-Novakovic, Gordana | Methods in molecular biology (Clifton, N.J.). | 25070328 | 2014; |
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| Projection Stereolithographic Fabrication of Human Adipose Stem Cell-Incorporated Biodegradable Scaffolds for Cartilage Tissue Engineering. | Sun, Aaron X; Lin, Hang; Beck, Angela M; Kilroy, Evan J; Tuan, Rocky S | Frontiers in bioengineering and biotechnology. | 26347860 | 2015; |
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| Human pluripotent stem cell-derived neural constructs for predicting neural toxicity. | Schwartz, Michael P; Hou, Zhonggang; Propson, Nicholas E; Zhang, Jue; Engstrom, Collin J; Santos Costa, Vitor; Jiang, Peng; Nguyen, Bao Kim; Bolin, Jennifer M; Daly, William; Wang, Yu; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James A | Proceedings of the National Academy of Sciences of the United States of America. | 26392547 | 2015 Oct 6; |
| Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin. | Pellett, Sabine; Schwartz, Michael P; Tepp, William H; Josephson, Richard; Scherf, Jacob M; Pier, Christina L; Thomson, James A; Murphy, William L; Johnson, Eric A | Scientific reports. | 26411797 | 2015; |
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| Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology. | Saxena, Kapil; Blutt, Sarah E; Ettayebi, Khalil; Zeng, Xi-Lei; Broughman, James R; Crawford, Sue E; Karandikar, Umesh C; Sastri, Narayan P; Conner, Margaret E; Opekun, Antone R; Graham, David Y; Qureshi, Waqar; Sherman, Vadim; Foulke-Abel, Jennifer; In, J | Journal of virology. | 26446608 | 2015 Oct 07; |
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| Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. | Jung, Youngmee; Ji, HaYeun; Chen, Zaozao; Fai Chan, Hon; Atchison, Leigh; Klitzman, Bruce; Truskey, George; Leong, Kam W | Scientific reports. | 26456074 | 2015; |
| Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia. | Kong, Jianping; Sai, Hong; Crissey, Mary Ann S; Jhala, Nirag; Falk, Gary W; Ginsberg, Gregory G; Abrams, Julian A; Nakagawa, Hiroshi; Wang, Kenneth; Rustgi, Anil K; Wang, Timothy C; Lynch, John P | Oncotarget. | 26460825 | 2015 Oct 20; |
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| Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain depends on disease status. | Chun, Young Wook; Voyles, David E; Rath, Rutwik; Hofmeister, Lucas H; Boire, Timothy C; Wilcox, Henry; Lee, Jae Han; Bellan, Leon M; Hong, Charles C; Sung, Hak-Joon | Journal of biomechanics. | 26476764 | 2015 Nov 5; |
| Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization. | McCarty, William J; Prodanov, Ljupcho; Bale, Shyam Sundhar; Bhushan, Abhinav; Jindal, Rohit; Yarmush, Martin L; Usta, O Berk | Journal of visualized experiments : JoVE. | 26485274 | 2015; |
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| Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1?/nerve growth factor signaling. | Jiang, Yangzi; Hu, Changchang; Yu, Shuting; Yan, Junwei; Peng, Hsuan; Ouyang, Hong Wei; Tuan, Rocky S | Arthritis research & therapy. | 26577823 | 2015; |
| Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model. | Rivera-Burgos, Dinelia; Sarkar, Ujjal; Lever, Amanda R; Avram, Michael J; Coppeta, Jonathan R; Wishnok, John S; Borenstein, Jeffrey T; Tannenbaum, Steven R | Drug metabolism and disposition: the biological fate of chemicals. | 26586376 | 2016 Feb; |
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| Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. | Eng, George; Lee, Benjamin W; Protas, Lev; Gagliardi, Mark; Brown, Kristy; Kass, Robert S; Keller, Gordon; Robinson, Richard B; Vunjak-Novakovic, Gordana | Nature communications | 26785135 | 2016 Jan 19 |
| High-density lipoprotein subclass measurements improve mortality risk prediction, discrimination and reclassification in a cardiac catheterization cohort. | McGarrah, Robert W; Craig, Damian M; Haynes, Carol; Dowdy, Z Elaine; Shah, Svati H; Kraus, William E | Atherosclerosis. | 26803432 | 2016 Mar; |
| Angiotensin II Induced Cardiac Dysfunction on a Chip. | Horton, Renita E; Yadid, Moran; McCain, Megan L; Sheehy, Sean P; Pasqualini, Francesco S; Park, Sung-Jin; Cho, Alexander; Campbell, Patrick; Parker, Kevin Kit | PloS one | 26808388 | 2016 |
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| Enterohemorrhagic Escherichia coli reduce mucus and intermicrovillar bridges in human stem cell-derived colonoids. | In, Julie; Foulke-Abel, Jennifer; Zachos, Nicholas C; Hansen, Anne-Marie; Kaper, James B; Bernstein, Harris D; Halushka, Marc; Blutt, Sarah; Estes, Mary K; Donowitz, Mark; Kovbasnjuk, Olga | Cellular and molecular gastroenterology and hepatology. | 26855967 | 2016 Jan 1; |
| Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy. | Aratyn-Schaus, Yvonne; Pasqualini, Francesco S; Yuan, Hongyan; McCain, Megan L; Ye, George J C; Sheehy, Sean P; Campbell, Patrick H; Parker, Kevin Kit | The Journal of cell biology. | 26858266 | 2016 Feb 15; |
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| Transdifferentiation of human endothelial progenitors into smooth muscle cells. | Ji, HaYeun; Atchison, Leigh; Chen, Zaozao; Chakraborty, Syandan; Jung, Youngmee; Truskey, George A; Christoforou, Nicolas; Leong, Kam W | Biomaterials. | 26874281 | 2016 Apr; |
| Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators. | Moyle-Heyrman, Georgette; Schipma, Matthew J; Dean, Matthew; Davis, David A; Burdette, Joanna E | Journal of ovarian research. | 26879975 | 2016 Feb 15; |
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| Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels. | Zanotelli, Matthew R; Ardalani, Hamisha; Zhang, Jue; Hou, Zhonggang; Nguyen, Eric H; Swanson, Scott; Nguyen, Bao Kim; Bolin, Jennifer; Elwell, Angela; Bischel, Lauren L; Xie, Angela W; Stewart, Ron; Beebe, David J; Thomson, James A; Schwartz, Michael P; Murphy, William L | Acta biomaterialia. | 26945632 | 2016 Apr 15; |
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| Modeling statin myopathy in a human skeletal muscle microphysiological system. | Ananthakumar, Anandita; Liu, Yiling; Fernandez, Cristina E; Truskey, George A; Voora, Deepak | PloS one | 33237943 | 2020 |
| Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification. | Qiu, Jingyao; Nordling, Sofia; Vasavada, Hema H; Butcher, Eugene C; Hirschi, Karen K | Cell reports | 33264627 | 2020 Dec 01 |
| Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS). | Sakolish, Courtney; Reese, Celeste E; Luo, Yu-Syuan; Valdiviezo, Alan; Schurdak, Mark E; Gough, Albert; Taylor, D Lansing; Chiu, Weihsueh A; Vernetti, Lawrence A; Rusyn, Ivan | Toxicology | 33307106 | 2021 01 30 |
| Electroencephalographic Seizures in Emergency Department Patients After Treatment for Convulsive Status Epilepticus. | Zehtabchi, Shahriar; Silbergleit, Robert; Chamberlain, James M; Shinnar, Shlomo; Elm, Jordan J; Underwood, Ellen; Rosenthal, Eric S; Bleck, Thomas P; Kapur, Jaideep | Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society | 33337664 | 2020 Dec 11 |
| Modeling the Complexity of the Metastatic Niche Ex Vivo. | Clark, Amanda M | Methods in molecular biology (Clifton, N.J.) | 33340364 | 2021 |
| A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®. | Bircsak, Kristin M; DeBiasio, Richard; Miedel, Mark; Alsebahi, Alaa; Reddinger, Ryan; Saleh, Anthony; Shun, Tongying; Vernetti, Lawrence A; Gough, Albert | Toxicology | 33359578 | 2021 Feb 28 |
| An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy. | Hachey, Stephanie J; Movsesyan, Silva; Nguyen, Quy H; Burton-Sojo, Giselle; Tankazyan, Ani; Wu, Jie; Hoang, Tuyen; Zhao, Da; Wang, Shuxiong; Hatch, Michaela M; Celaya, Elizabeth; Gomez, Samantha; Chen, George T; Davis, Ryan T; Nee, Kevin; Pervolarakis, Nicholas; Lawson, Devon A; Kessenbrock, Kai; Lee, Abraham P; Lowengrub, John; Waterman, Marian L; Hughes, Christopher C W | Lab on a chip | 33605955 | 2021 04 07 |
| Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues. | Song, H-H Greco; Lammers, Alex; Sundaram, Subramanian; Rubio, Logan; Chen, Amanda X; Li, Linqing; Eyckmans, Jeroen; Bhatia, Sangeeta N; Chen, Christopher S | Advanced functional materials | 33613149 | 2020 Nov 25 |
| Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease. | Lidberg, Kevin A; Annalora, Andrew J; Jozic, Marija; Elson, Daniel J; Wang, Lu; Bammler, Theo K; Ramm, Susanne; Monteiro, Maria Beatriz; Himmelfarb, Jonathan; Marcus, Craig B; Iversen, Patrick L; Kelly, Edward J | Scientific reports | 33633318 | 2021 Feb 25 |
| Interspecies chimeric conditions affect the developmental rate of human pluripotent stem cells. | Brown, Jared; Barry, Christopher; Schmitz, Matthew T; Argus, Cara; Bolin, Jennifer M; Schwartz, Michael P; Van Aartsen, Amy; Steill, John; Swanson, Scott; Stewart, Ron; Thomson, James A; Kendziorski, Christina | PLoS computational biology | 33647016 | 2021 03 |
| Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling. | Mina, Sara G; Alaybeyoglu, Begum; Murphy, William L; Thomson, James A; Stokes, Cynthia L; Cirit, Murat | Frontiers in big data | 33693346 | 2019 |
| Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers. | Chen, Amanda X; Chhabra, Arnav; Song, H-H Greco; Fleming, Heather E; Chen, Christopher S; Bhatia, Sangeeta N | Advanced functional materials | 33776613 | 2020 Nov 25 |
| Vascular endothelial cell specification in health and disease. | Marziano, Corina; Genet, Gael; Hirschi, Karen K | Angiogenesis | 33844116 | 2021 Apr 12 |
| Directed Differentiation of Hemogenic Endothelial Cells from Human Pluripotent Stem Cells. | Nelson, Elizabeth A; Qiu, Jingyao; Chavkin, Nicholas W; Hirschi, Karen K | Journal of visualized experiments : JoVE | 33871448 | 2021 03 31 |
| Early Neurologic Recovery, Practice Pattern Variation, and the Risk of Endotracheal Intubation Following Established Status Epilepticus. | Rosenthal, Eric S; Elm, Jordan J; Ingles, James; Rogers, Alexander J; Terndrup, Thomas E; Holsti, Maija; Thomas, Danny G; Babcock, Lynn; Okada, Pamela J; Lipsky, Robert H; Miller, Joseph B; Hickey, Robert W; Barra, Megan E; Bleck, Thomas P; Cloyd, James C; Silbergleit, Robert; Lowenstein, Daniel H; Coles, Lisa D; Kapur, Jaideep; Shinnar, Shlomo; Chamberlain, James M; Established Status Epilepticus Treatment Trial Study Group | Neurology | 34032604 | 2021 05 11 |
| Platforms to test the temporospatial capabilities of carrier systems in delivering growth factors to benefit vascular bioengineering. | Argueta, Lissenya B; Niles, Jean A; Sakamoto, Jason; Liu, Xuewu; Vega, Stephanie P; Frank, Luba; Paessler, Marco; Cortiella, Joaquin; Nichols, Joan E | Nanomedicine : nanotechnology, biology, and medicine | 34147665 | 2021 08 |
| The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation. | Chavkin, Nicholas W; Sano, Soichi; Wang, Ying; Oshima, Kosei; Ogawa, Hayato; Horitani, Keita; Sano, Miho; MacLauchlan, Susan; Nelson, Anders; Setia, Karishma; Vippa, Tanvi; Watanabe, Yosuke; Saucerman, Jeffrey J; Hirschi, Karen K; Gokce, Noyan; Walsh, Kenneth | Journal of the American Heart Association | 34155901 | 2021 07 06 |
| Non-destructive vacuum-assisted measurement of lung elastic modulus. | Chen, Jiawen; Mir, Seyed Mohammad; Pinezich, Meghan R; O'Neill, John D; Guenthart, Brandon A; Bacchetta, Matthew; Vunjak-Novakovic, Gordana; Huang, Sarah X L; Kim, Jinho | Acta biomaterialia | 34192570 | 2021 Sep 01 |
| A High-Throughput Mechanical Activator for Cartilage Engineering Enables Rapid Screening of in vitro Response of Tissue Models to Physiological and Supra-Physiological Loads. | Capuana, Elisa; Marino, Davide; Di Gesù, Roberto; La Carrubba, Vincenzo; Brucato, Valerio; Tuan, Rocky S; Gottardi, Riccardo | Cells, tissues, organs | 34261061 | 2022 |
| Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation. | Blutt, Sarah E; Crawford, Sue E; Bomidi, Carolyn; Zeng, Xi-Lei; Broughman, James R; Robertson, Matthew; Coarfa, Cristian; Tessier, Mary Elizabeth M; Savidge, Tor; Hollinger, F Blaine; Curley, Steven A; Donowitz, Mark; Estes, Mary K | American journal of physiology. Gastrointestinal and liver physiology | 34288725 | 2021 09 01 |
| The vascular niche in next generation microphysiological systems. | Ewald, Makena L; Chen, Yu-Hsi; Lee, Abraham P; Hughes, Christopher C W | Lab on a chip | 34396383 | 2021 09 07 |
| High resolution stereolithography fabrication of perfusable scaffolds to enable long-term meso-scale hepatic culture for disease modeling. | Sphabmixay, Pierre; Raredon, Micha Sam Brickman; Wang, Alex J-S; Lee, Howon; Hammond, Paula T; Fang, Nicholas X; Griffith, Linda G | Biofabrication | 34479229 | 2021 09 21 |
| Understanding neural stem cell regulation in vivo and applying the insights to cell therapy for strokes. | Genet, Nafiisha; Hirschi, Karen K | Regenerative medicine | 34498495 | 2021 09 |
| A Mesoscale 3D Culture System for Native and Engineered Biphasic Tissues: Application to the Osteochondral Unit. | Chiesa, Irene; Di Gesù, Roberto; Overholt, Kalon J; Gottardi, Riccardo | Methods in molecular biology (Clifton, N.J.) | 34520018 | 2022 |
| Prediction of hepatic drug clearance with a human microfluidic four-cell liver acinus microphysiology system. | Sakolish, Courtney; Luo, Yu-Syuan; Valdiviezo, Alan; Vernetti, Lawrence A; Rusyn, Ivan; Chiu, Weihsueh A | Toxicology | 34543702 | 2021 Nov |
| milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues. | Tamargo, Manuel Alejandro; Nash, Trevor Ray; Fleischer, Sharon; Kim, Youngbin; Vila, Olaia Fernandez; Yeager, Keith; Summers, Max; Zhao, Yimu; Lock, Roberta; Chavez, Miguel; Costa, Troy; Vunjak-Novakovic, Gordana | ACS biomaterials science & engineering | 34668692 | 2021 11 08 |
| Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency. | Laemmle, Alexander; Poms, Martin; Hsu, Bernadette; Borsuk, Mariia; Rüfenacht, Véronique; Robinson, Joshua; Sadowski, Martin C; Nuoffer, Jean-Marc; Häberle, Johannes; Willenbring, Holger | Hepatology (Baltimore, Md.) | 34786702 | 2021 Nov 16 |
| Organ-on-a-chip model of vascularized human bone marrow niches. | Glaser, Drew E; Curtis, Matthew B; Sariano, Peter A; Rollins, Zachary A; Shergill, Bhupinder S; Anand, Aravind; Deely, Alyssa M; Shirure, Venktesh S; Anderson, Leif; Lowen, Jeremy M; Ng, Natalie R; Weilbaecher, Katherine; Link, Daniel C; George, Steven C | Biomaterials | 34810038 | 2022 01 |
| Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. | Eicher, Alexandra K; Kechele, Daniel O; Sundaram, Nambirajan; Berns, H Matthew; Poling, Holly M; Haines, Lauren E; Sanchez, J Guillermo; Kishimoto, Keishi; Krishnamurthy, Mansa; Han, Lu; Zorn, Aaron M; Helmrath, Michael A; Wells, James M | Cell stem cell | 34856121 | 2022 01 06 |
| Cyclosporine Induces Fenestra-Associated Injury in Human Renal Microvessels In Vitro. | Nagao, Ryan J; Marcu, Raluca; Shin, Yu Jung; Lih, Daniel; Xue, Jun; Arang, Nadia; Wei, Ling; Akilesh, Shreeram; Kaushansky, Alexis; Himmelfarb, Jonathan; Zheng, Ying | ACS biomaterials science & engineering | 34927415 | 2022 01 10 |
| Network inference with Granger causality ensembles on single-cell transcriptomics. | Deshpande, Atul; Chu, Li-Fang; Stewart, Ron; Gitter, Anthony | Cell reports | 35139376 | 2022 02 08 |
| An autonomously swimming biohybrid fish designed with human cardiac biophysics. | Lee, Keel Yong; Park, Sung-Jin; Matthews, David G; Kim, Sean L; Marquez, Carlos Antonio; Zimmerman, John F; Ardoña, Herdeline Ann M; Kleber, Andre G; Lauder, George V; Parker, Kevin Kit | Science (New York, N.Y.) | 35143298 | 2022 02 11 |
| Endothelial Cell Differentiation and Hemogenic Specification. | Aragon, Jordon W; Hirschi, Karen K | Cold Spring Harbor perspectives in medicine | 35193895 | 2022 07 29 |
| Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity. | Pamies, David; Wiersma, Daphne; Katt, Moriah E; Zhao, Liang; Burtscher, Johannes; Harris, Georgina; Smirnova, Lena; Searson, Peter C; Hartung, Thomas; Hogberg, Helena T | Neurobiology of disease | 35398340 | 2022 07 |
| Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia. | Cruz, Nelly M; Reddy, Raghava; McFaline-Figueroa, José L; Tran, Christine; Fu, Hongxia; Freedman, Benjamin S | Nature biomedical engineering | 35478224 | 2022 04 |
| Kidney microphysiological models for nephrotoxicity assessment. | Mahadeo, Anish; Yeung, Catherine K; Himmelfarb, Jonathan; Kelly, Edward J | Current opinion in toxicology | 35495549 | 2022 Jun |
| Comparison of Bayesian vs Frequentist Adaptive Trial Design in the Stroke Hyperglycemia Insulin Network Effort Trial. | Broglio, Kristine; Meurer, William J; Durkalski, Valerie; Pauls, Qi; Connor, Jason; Berry, Donald; Lewis, Roger J; Johnston, Karen C; Barsan, William G | JAMA network open | 35544137 | 2022 05 02 |
| A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models. | Singh, Dharaminder; Deosarkar, Sudhir P; Cadogan, Elaine; Flemington, Vikki; Bray, Alysha; Zhang, Jingwen; Reiserer, Ronald S; Schaffer, David K; Gerken, Gregory B; Britt, Clayton M; Werner, Erik M; Gibbons, Francis D; Kostrzewski, Tomasz; Chambers, Chris | PLoS biology | 35617197 | 2022 05 |
| A vascularized model of the human liver mimics regenerative responses. | Chhabra, Arnav; Song, H-H Greco; Grzelak, Katarzyna A; Polacheck, William J; Fleming, Heather E; Chen, Christopher S; Bhatia, Sangeeta N | Proceedings of the National Academy of Sciences of the United States of America | 35763565 | 2022 Jul 12 |
| Recreating the heart's helical structure-function relationship with focused rotary jet spinning. | Chang, Huibin; Liu, Qihan; Zimmerman, John F; Lee, Keel Yong; Jin, Qianru; Peters, Michael M; Rosnach, Michael; Choi, Suji; Kim, Sean L; Ardoña, Herdeline Ann M; MacQueen, Luke A; Chantre, Christophe O; Motta, Sarah E; Cordoves, Elizabeth M; Parker, Kevin | Science (New York, N.Y.) | 35857545 | 2022 07 08 |
| Engineering Modular 3D Liver Culture Microenvironments In Vitro to Parse the Interplay between Biophysical and Biochemical Microenvironment Cues on Hepatic Phenotypes. | Wang, Alex J; Allen, Allysa; Sofman, Marianna; Sphabmixay, Pierre; Yildiz, Ece; Griffith, Linda G | Advanced nanobiomed research | 35872804 | 2022 Jan |
| Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease. | Li, Sienna R; Gulieva, Ramila E; Helms, Louisa; Cruz, Nelly M; Vincent, Thomas; Fu, Hongxia; Himmelfarb, Jonathan; Freedman, Benjamin S | Nature communications | 36564419 | 2022 Dec 23 |
| Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome. | Abutaleb, Nadia O; Atchison, Leigh; Choi, Leandro; Bedapudi, Akhil; Shores, Kevin; Gete, Yantenew; Cao, Kan; Truskey, George A | Scientific reports | 36977745 | 2023 Mar 28 |
| Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone. | Genet, Nafiisha; Genet, Gael; Chavkin, Nicholas W; Paila, Umadevi; Fang, Jennifer S; Vasavada, Hema H; Goldberg, Joshua S; Acharya, Bipul R; Bhatt, Neha S; Baker, Kasey; McDonnell, Stephanie P; Huba, Mahalia; Sankaranarayanan, Danya; Ma, Gerry Z M; Eichmann, Anne; Thomas, Jean-Leon; Ffrench-Constant, Charles; Hirschi, Karen K | Cell reports | 37043357 | 2023 Apr 25 |
| Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice. | Kam, Chen Yuan; Singh, Ishani D; Gonzalez, David G; Matte-Martone, Catherine; Solá, Paloma; Solanas, Guiomar; Bonjoch, Júlia; Marsh, Edward; Hirschi, Karen K; Greco, Valentina | Cell | 37167971 | 2023 May 25 |
| MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis. | Wu, Yinyu; Paila, Umadevi; Genet, Gael; Hirschi, Karen K | Developmental cell | 37295435 | 2023 Jul 24 |
| One transgene, two myopathies: an MTM1 'cross gene therapy' for BIN1 deficiency? | Asgarian, Zeinab; Siam, Ala'a; Counsell, John R | Brain : a journal of neurology | 37738144 | 2023 Oct 03 |
| Emulator-based Bayesian inference on non-proportional scintillation models by compton-edge probing. | Breitenmoser, David; Cerutti, Francesco; Butterweck, Gernot; Kasprzak, Malgorzata Magdalena; Mayer, Sabine | Nature communications | 38012127 | 2023 Nov 28 |
| Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system. | Lidberg, Kevin A; Jones-Isaac, Kendan; Yang, Jade; Bain, Jacelyn; Wang, Lu; MacDonald, James W; Bammler, Theo K; Calamia, Justina; Thummel, Kenneth E; Yeung, Catherine K; Countryman, Stefanie; Koenig, Paul; Himmelfarb, Jonathan; Kelly, Edward J | NPJ microgravity | 38982119 | 2024 Jul 09 |
| Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP): study protocol for a multicenter, randomized, adaptive allocation clinical trial to identify the optimal duration of induced hypothermia for neuroprotection in comatose, adult survivors of after out-of-hospital cardiac arrest. | Meurer, William J; Schmitzberger, Florian F; Yeatts, Sharon; Ramakrishnan, Viswanathan; Abella, Benjamin; Aufderheide, Tom; Barsan, William; Benoit, Justin; Berry, Scott; Black, Joy; Bozeman, Nia; Broglio, Kristine; Brown, Jeremy; Brown, Kimberly; Carlozzi, Noelle; Caveney, Angela; Cho, Sung-Min; Chung-Esaki, Hangyul; Clevenger, Robert; Conwit, Robin; Cooper, Richelle; Crudo, Valentina; Daya, Mohamud; Harney, Deneil; Hsu, Cindy; Johnson, Nicholas J; Khan, Imad; Khosla, Shaveta; Kline, Peyton; Kratz, Anna; Kudenchuk, Peter; Lewis, Roger J; Madiyal, Chaitra; Meyer, Sara; Mosier, Jarrod; Mouammar, Marwan; Neth, Matthew; O'Neil, Brian; Paxton, James; Perez, Sofia; Perman, Sarah; Sozener, Cemal; Speers, Mickie; Spiteri, Aimee; Stevenson, Valerie; Sunthankar, Kavita; Tonna, Joseph; Youngquist, Scott; Geocadin, Romergryko; Silbergleit, Robert; ICECAP trial investigators | Trials | 39044295 | 2024 Jul 23 |
| Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. | Genet, Gael; Genet, Nafiisha; Paila, Umadevi; Cain, Shelby R; Cwiek, Aleksandra; Chavkin, Nicholas W; Serbulea, Vlad; Figueras, Agnès; Cerdà, Pau; McDonnell, Stephanie P; Sankaranarayanan, Danya; Huba, Mahalia; Nelson, Elizabeth A; Riera-Mestre, Antoni; Hirschi, Karen K | Circulation | 38126211 | 2024 Mar 19 |
| Development of a kidney microphysiological system hardware platform for microgravity studies. | Jones-Isaac, Kendan A; Lidberg, Kevin A; Yeung, Catherine K; Yang, Jade; Bain, Jacelyn; Ruiz, Micaela; Koenig, Greta; Koenig, Paul; Countryman, Stefanie; Himmelfarb, Jonathan; Kelly, Edward J | NPJ microgravity | 38734683 | 2024 May 11 |
| Interferon-γ induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease. | Juliar, Benjamin A; Stanaway, Ian B; Sano, Fumika; Fu, Hongxia; Smith, Kelly D; Akilesh, Shreeram; Scales, Suzie J; El Saghir, Jamal; Bhatraju, Pavan K; Liu, Esther; Yang, Johnson; Lin, Jennie; Eddy, Sean; Kretzler, Matthias; Zheng, Ying; Himmelfarb, Jonathan; Harder, Jennifer L; Freedman, Benjamin S | Cell reports | 38838223 | 2024 Jun 25 |
| Evaluation of Human Hepatocyte Drug Metabolism Carrying High-Risk or Protection-Associated Liver Disease Genetic Variants. | Faccioli, Lanuza A P; Cetin, Zeliha; Kocas-Kilicarslan, Zehra N; Ortiz, Kimberly; Sun, Yiyue; Hu, Zhiping; Kurihara, Takeshi; Tafaleng, Edgar N; Florentino, Rodrigo M; Wang, Zi; Xia, Mengying; Miedel, Mark T; Taylor, D Lansing; Behari, Jaideep; Ostrowska, Alina; Constantine, Robert; Li, Albert; Soto-Gutierrez, Alejandro | International journal of molecular sciences | 37686209 | 2023 Aug 29 |
| Impact of microgravity on a three-dimensional microphysiologic culture of the human kidney proximal tubule epithelium: cell response to serum and vitamin D. | Kelly, Edward; Lindberg, Kevin; Jones-Isaac, Kendan; Yang, Jade; Bain, Jacelyn; Wang, Lu; MacDonald, James; Bammler, Theo; Calamia, Justina; Thummel, Kenneth; Yeung, Catherine; Countryman, Stefanie; Koenig, Paul; Himmelfarb, Jonathan | Research square | 38196580 | 2023 Dec 21 |
| Development of a Kidney Microphysiological System Hardware Platform for Microgravity Studies. | Yeung, Catherine; Jones-Isaac, Kendan; Lindberg, Kevin; Yang, Jade; Bain, Jacelyn; Ruiz, Micaela; Koenig, Greta; Koenig, Paul; Countryman, Stefanie; Himmelfarb, Jonathan; Kelly, Edward | Research square | 38196654 | 2023 Dec 22 |
| Rational engineering of lung alveolar epithelium. | Leiby, Katherine L; Yuan, Yifan; Ng, Ronald; Raredon, Micha Sam Brickman; Adams, Taylor S; Baevova, Pavlina; Greaney, Allison M; Hirschi, Karen K; Campbell, Stuart G; Kaminski, Naftali; Herzog, Erica L; Niklason, Laura E | NPJ Regenerative medicine | 37117221 | 2023 Apr 28 |
| Human Hepatocellular response in Cholestatic Liver Diseases. | Ortiz, Kimberly; Cetin, Zeliha; Sun, Yiyue; Hu, Zhiping; Kurihara, Takeshi; Tafaleng, Edgar N; Florentino, Rodrigo M; Ostrowska, Alina; Soto-Gutierrez, Alejandro; Faccioli, Lanuza A P | Organogenesis | 37598346 | 2023 Dec 31 |
| iPSC-Derived Neurons from Patients with POLG Mutations Exhibit Decreased Mitochondrial Content and Dendrite Simplification. | Verma, Manish; Francis, Lily; Lizama, Britney N; Callio, Jason; Fricklas, Gabriella; Wang, Kent Z Q; Kaufman, Brett A; D'Aiuto, Leonardo; Stolz, Donna B; Watkins, Simon C; Nimgaonkar, Vishwajit L; Soto-Gutierrez, Alejandro; Goldstein, Amy; Chu, Charleen T | The American journal of pathology | 36414085 | 2023 Feb |
