Program Publications
Publications by Program
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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
Title | Authors | Journal | PubMedID | Publication Date |
---|---|---|---|---|
Transporters in drug-refractory epilepsy: clinical significance. | Marchi, N; Gonzalez-Martinez, J; Nguyen, M-T; Granata, T; Janigro, D | Clinical pharmacology and therapeutics | 20019694 | 2010 Jan |
Biophysics and dynamics of natural and engineered stem cell microenvironments. | Keung, Albert J; Healy, Kevin E; Kumar, Sanjay; Schaffer, David V | Wiley interdisciplinary reviews. Systems biology and medicine | 20836010 | 2010 Jan-Feb |
Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of *-catenin signaling. | Cimetta, Elisa; Cannizzaro, Christopher; James, Richard; Biechele, Travis; Moon, Randall T; Elvassore, Nicola; Vunjak-Novakovic, Gordana | Lab on a chip. | 20936235 | 2010 Dec 7; |
Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces. | Pham, Christine T N; Mitchell, Lynne M; Huang, Jennifer L; Lubniewski, Christopher M; Schall, Otto F; Killgore, J Kendall; Pan, Dipanjan; Wickline, Samuel A; Lanza, Gregory M; Hourcade, Dennis E | The Journal of biological chemistry | 21047788 | 2011 Jan 7 |
Informatics and standards for nanomedicine technology. | Thomas, Dennis G; Klaessig, Fred; Harper, Stacey L; Fritts, Martin; Hoover, Mark D; Gaheen, Sharon; Stokes, Todd H; Reznik-Zellen, Rebecca; Freund, Elaine T; Klemm, Juli D; Paik, David S; Baker, Nathan A | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 21721140 | 2011 Jun 30 |
Nanotherapeutic approaches for the treatment of rheumatoid arthritis. | Pham, Christine T N | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. | 21837725 | 2011 Nov-Dec; |
Manganese-based MRI contrast agents: past, present and future. | Pan, Dipanjan; Schmieder, Anne H; Wickline, Samuel A; Lanza, Gregory M | Tetrahedron. | 22043109 | 2011 Nov 04; |
Interaction of melittin peptides with perfluorocarbon nanoemulsion particles. | Lee, Sun-Joo; Schlesinger, Paul H; Wickline, Samuel A; Lanza, Gregory M; Baker, Nathan A | The journal of physical chemistry. B | 22050303 | 2011 Dec 29 |
Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip. | Grosberg, Anna; Alford, Patrick W; McCain, Megan L; Parker, Kevin Kit | Lab on a chip | 22072288 | 2011 Dec 21 |
An early investigation of ytterbium nanocolloids for selective and quantitative "multicolor" spectral CT imaging. | Pan, Dipanjan; Schirra, Carsten O; Senpan, Angana; Schmieder, Anne H; Stacy, Allen J; Roessl, Ewald; Thran, Axel; Wickline, Samuel A; Proska, Roland; Lanza, Gregory M | ACS nano | 22385324 | 2012 Apr 24 |
An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project. | Meurer, William J; Lewis, Roger J; Tagle, Danilo; Fetters, Michael D; Legocki, Laurie; Berry, Scott; Connor, Jason; Durkalski, Valerie; Elm, Jordan; Zhao, Wenle; Frederiksen, Shirley; Silbergleit, Robert; Palesch, Yuko; Berry, Donald A; Barsan, William G | Annals of emergency medicine | 22424650 | 2012 Oct |
ICAM-1 and nanomedicine: nature's doorway to the extravascular tissue realm. | Lanza, Gregory M | Arteriosclerosis, thrombosis, and vascular biology | 22517363 | 2012 May |
Muscle on a chip: in vitro contractility assays for smooth and striated muscle. | Grosberg, Anna; Nesmith, Alexander P; Goss, Josue A; Brigham, Mark D; McCain, Megan L; Parker, Kevin Kit | Journal of pharmacological and toxicological methods | 22521339 | 2012 May-Jun |
Effect of insurance status on postacute care among working age stroke survivors. | Skolarus, L E; Meurer, W J; Burke, J F; Prvu Bettger, J; Lisabeth, L D | Neurology | 22551730 | 2012 May 15 |
Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier. | Janigro, Damir | Epilepsia. | 22612806 | 2012 Jun; |
Adaptive clinical trials: a partial remedy for the therapeutic misconception? | Meurer, William J; Lewis, Roger J; Berry, Donald A | JAMA : the journal of the American Medical Association | 22692168 | 2012 Jun 13 |
Antiangiogenic nanotherapy with lipase-labile Sn-2 fumagillin prodrug. | Pan, Dipanjan; Sanyal, Nibedita; Schmieder, Anne H; Senpan, Angana; Kim, Benjamin; Yang, Xiaoxia; Hu, Grace; Allen, John S; Gross, Richard W; Wickline, Samuel A; Lanza, Gregory M | Nanomedicine (London, England) | 22709347 | 2012 Oct |
Simulation of fusion-mediated nanoemulsion interactions with model lipid bilayers. | Lee, Sun-Joo; Schlesinger, Paul H; Wickline, Samuel A; Lanza, Gregory M; Baker, Nathan A | Soft matter | 22712024 | 2012 Jan 1 |
The contribution of cellular mechanotransduction to cardiomyocyte form and function. | Sheehy, Sean P; Grosberg, Anna; Parker, Kevin Kit | Biomechanics and modeling in mechanobiology | 22772714 | 2012 Nov |
A mini-microscope for in situ monitoring of cells. | Kim, Sang Bok; Koo, Kyo-in; Bae, Hojae; Dokmeci, Mehmet R; Hamilton, Geraldine A; Bahinski, Anthony; Kim, Sun Min; Ingber, Donald E; Khademhosseini, Ali | Lab on a chip | 22911426 | 2012 Oct 21 |
Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence. | Hu, Lingzhi; Chen, Junjie; Yang, Xiaoxia; Caruthers, Shelton D; Lanza, Gregory M; Wickline, Samuel A | Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine | 22915328 | 2012 Aug 22 |
Suppression of inflammation in a mouse model of rheumatoid arthritis using targeted lipase-labile fumagillin prodrug nanoparticles. | Zhou, Hui-Fang; Yan, Huimin; Senpan, Angana; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T N | Biomaterials | 22922023 | 2012 Nov |
Nanoinformatics: developing new computing applications for nanomedicine. | Maojo, V; Fritts, M; Martin-Sanchez, F; De la Iglesia, D; Cachau, R E; Garcia-Remesal, M; Crespo, J; Mitchell, J A; Anguita, A; Baker, N; Barreiro, J M; Benitez, S E; De la Calle, G; Facelli, J C; Ghazal, P; Geissbuhler, A; Gonzalez-Nilo, F; Graf, N; Gran | Computing in science & engineering | 22942787 | 2012 Jun 1 |
Nanoinformatics: developing new computing applications for nanomedicine. | Maojo, V; Fritts, M; Martin-Sanchez, F; De la Iglesia, D; Cachau, R E; Garcia-Remesal, M; Crespo, J; Mitchell, J A; Anguita, A; Baker, N; Barreiro, J M; Benitez, S E; De la Calle, G; Facelli, J C; Ghazal, P; Geissbuhler, A; Gonzalez-Nilo, F; Graf, N; Grangeat, P; Hermosilla, I; Hussein, R; Kern, J; Koch, S; Legre, Y; Lopez-Alonso, V; Lopez-Campos, G; Milanesi, L; Moustakis, V; Munteanu, C; Otero, P; Pazos, A; Perez-Rey, D; Potamias, G; Sanz, F; Kulikowski, C | Computing in science & engineering | 22942787 | 2012 Jun 1 |
Near infrared imaging of EGFR of oral squamous cell carcinoma in mice administered arsenic trioxide. | Zhang, Lingbo; Wang, Kezheng; Zhao, Falin; Hu, Weiping; Chen, Junjie; Lanza, Gregory M; Shen, Baozhong; Zhang, Bin | PloS one | 23029451 | 2012 |
Angiogenesis is required for stress fracture healing in rats. | Tomlinson, Ryan E; McKenzie, Jennifer A; Schmieder, Anne H; Wohl, Gregory R; Lanza, Gregory M; Silva, Matthew J | Bone | 23044046 | 2013 Jan |
Bursting drops in solid dielectrics caused by high voltages. | Wang, Qiming; Suo, Zhigang; Zhao, Xuanhe | Nature communications. | 23093194 | 2012; |
Elucidation of adhesion-dependent spontaneous apoptosis in macrophages using phase separated PEG/polyurethane films. | Zachman, Angela L; Page, Jonathan M; Prabhakar, Gayathri; Guelcher, Scott A; Sung, Hak-Joon | Acta biomaterialia. | 23128157 | 2013 Feb; |
A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. | Huh, Dongeun; Leslie, Daniel C; Matthews, Benjamin D; Fraser, Jacob P; Jurek, Samuel; Hamilton, Geraldine A; Thorneloe, Kevin S; McAlexander, Michael Allen; Ingber, Donald E | Science translational medicine | 23136042 | 2012 Nov 7 |
Second Generation Gold Nanobeacons for Robust K-Edge Imaging with Multi-Energy CT. | Schirra, Carsten O; Senpan, Angana; Roessl, Ewald; Thran, Axel; Stacy, Allen J; Wu, Lina; Proska, Roland; Pan, Dipanjan | Journal of materials chemistry. | 23185109 | 2012 Jan 01; |
Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells. | Cimetta, Elisa; Sirabella, Dario; Yeager, Keith; Davidson, Kathryn; Simon, Joseph; Moon, Randall T; Vunjak-Novakovic, Gordana | Lab on a chip | 23232509 | 2013 Feb 7 |
The inexorable rise of AKI: can we bend the growth curve? | Siew, Edward D; Himmelfarb, Jonathan | Journal of the American Society of Nephrology : JASN. | 23243210 | 2013 Jan; |
ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format. | Thomas, Dennis G; Gaheen, Sharon; Harper, Stacey L; Fritts, Martin; Klaessig, Fred; Hahn-Dantona, Elizabeth; Paik, David; Pan, Sue; Stafford, Grace A; Freund, Elaine T; Klemm, Juli D; Baker, Nathan A | BMC biotechnology | 23311978 | 2013 |
Regenerative medicine in 2012: the coming of age of musculoskeletal tissue engineering. | Tuan, Rocky S | Nature reviews. Rheumatology. | 23321611 | 2013 Feb; |
Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis. | Campanholle, Gabriela; Ligresti, Giovanni; Gharib, Sina A; Duffield, Jeremy S | American journal of physiology. Cell physiology. | 23325411 | 2013 Apr 1; |
Modeling boundary conditions for balanced proliferation in metastatic latency. | Taylor, Donald P; Wells, Jakob Z; Savol, Andrej; Chennubhotla, Chakra; Wells, Alan | Clinical cancer research : an official journal of the American Association for Cancer Research | 23329811 | 2013 Mar 1 |
Multifunctionality and control of the crumpling and unfolding of large-area graphene. | Zang, Jianfeng; Ryu, Seunghwa; Pugno, Nicola; Wang, Qiming; Tu, Qing; Buehler, Markus J; Zhao, Xuanhe | Nature materials. | 23334002 | 2013 Apr; |
Nonsteady state oxygen transport in engineered tissue: implications for design. | Ehsan, Seema M; George, Steven C | Tissue engineering. Part A. | 23350630 | 2013 Jun; |
Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes. | Robertson, Claire; Tran, David D; George, Steven C | Stem cells (Dayton, Ohio). | 23355363 | 2013 May; |
Engineering challenges for instrumenting and controlling integrated organ-on-chip systems. | Wikswo, John P; Block 3rd, Frank E; Cliffel, David E; Goodwin, Cody R; Marasco, Christina C; Markov, Dmitry A; McLean, David L; McLean, John A; McKenzie, Jennifer R; Reiserer, Ronald S; Samson, Philip C; Schaffer, David K; Seale, Kevin T; Sherrod, Stacy D | IEEE transactions on bio-medical engineering | 23380852 | 2013 Mar |
Standardizing data. | Baker, Nathan A; Klemm, Juli D; Harper, Stacey L; Gaheen, Sharon; Heiskanen, Mervi; Rocca-Serra, Philippe; Sansone, Susanna-Assunta | Nature nanotechnology | 23380926 | 2013 Feb |
A new dynamic in vitro modular capillaries-venules modular system: cerebrovascular physiology in a box. | Cucullo, Luca; Hossain, Mohammed; Tierney, William; Janigro, Damir | BMC neuroscience. | 23388041 | 2013; |
Does Systemic Inflammation Play a Role in Pediatric Psychosis? | Falcone, Tatiana; Carlton, Erin; Lee, Catherine; Janigro, Mattia; Fazio, Vince; Forcen, Fernando Espi; Franco, Kathleen; Janigro, Damir | Clinical schizophrenia & related psychoses | 23491967 | 2015 |
EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury. | Kida, Yujiro; Ieronimakis, Nicholas; Schrimpf, Claudia; Reyes, Morayma; Duffield, Jeremy S | Journal of the American Society of Nephrology : JASN. | 23492730 | 2013 Mar; |
Poly(?-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells. | Crowder, Spencer W; Liang, Yi; Rath, Rutwik; Park, Andrew M; Maltais, Simon; Pintauro, Peter N; Hofmeister, William; Lim, Chee C; Wang, Xintong; Sung, Hak-Joon | Nanomedicine (London, England). | 23530764 | 2013 Nov; |
Bioreactor engineering of stem cell environments. | Tandon, Nina; Marolt, Darja; Cimetta, Elisa; Vunjak-Novakovic, Gordana | Biotechnology advances | 23531529 | 2013 Mar 24 |
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro. | Nguyen, Duc-Huy T; Stapleton, Sarah C; Yang, Michael T; Cha, Susie S; Choi, Colin K; Galie, Peter A; Chen, Christopher S | Proceedings of the National Academy of Sciences of the United States of America. | 23569284 | 2013 Apr 23; |
A therapy for liver failure found in the JNK yard. | Willenbring, Holger; Grompe, Markus | Cell. | 23582318 | 2013 Apr 11; |
Three-dimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells. | Crowder, Spencer W; Prasai, Dhiraj; Rath, Rutwik; Balikov, Daniel A; Bae, Hojae; Bolotin, Kirill I; Sung, Hak-Joon | Nanoscale. | 23592029 | 2013 May 21; |
Production and assessment of decellularized pig and human lung scaffolds. | Nichols, Joan E; Niles, Jean; Riddle, Michael; Vargas, Gracie; Schilagard, Tuya; Ma, Liang; Edward, Kert; La Francesca, Saverio; Sakamoto, Jason; Vega, Stephanie; Ogadegbe, Marie; Mlcak, Ronald; Deyo, Donald; Woodson, Lee; McQuitty, Christopher; Lick, Sco | Tissue engineering. Part A. | 23638920 | 2013 Sep; |
Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. | Zhang, Donghui; Shadrin, Ilya Y; Lam, Jason; Xian, Hai-Qian; Snodgrass, H Ralph; Bursac, Nenad | Biomaterials. | 23642535 | 2013 Jul; |
Mechanistic validation. | Hartung, Thomas; Hoffmann, Sebastian; Stephens, Martin | ALTEX | 23665802 | 2013 |
Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. | Ma, Xiaocui; Duan, Yuyou; Tschudy-Seney, Benjamin; Roll, Garrett; Behbahan, Iman Saramipoor; Ahuja, Tijess P; Tolstikov, Vladimir; Wang, Charles; McGee, Jeannine; Khoobyari, Shiva; Nolta, Jan A; Willenbring, Holger; Zern, Mark A | Stem cells translational medicine. | 23681950 | 2013 Jun; |
Engineering skeletal muscle repair. | Juhas, Mark; Bursac, Nenad | Current opinion in biotechnology. | 23711735 | 2013 Oct; |
Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip. | McCain, Megan L; Sheehy, Sean P; Grosberg, Anna; Goss, Josue A; Parker, Kevin Kit | Proceedings of the National Academy of Sciences of the United States of America. | 23716679 | 2013 Jun 11; |
Pericytes in kidney fibrosis. | Ren, Shuyu; Duffield, Jeremy S | Current opinion in nephrology and hypertension. | 23722183 | 2013 Jul; |
A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays. | Hsu, Yu-Hsiang; Moya, Monica L; Hughes, Christopher C W; George, Steven C; Lee, Abraham P | Lab on a chip. | 23723013 | 2013 Aug 7; |
Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts. | Shi, Mingjian; Majumdar, Devi; Gao, Yandong; Brewer, Bryson M; Goodwin, Cody R; McLean, John A; Li, Deyu; Webb, Donna J | Lab on a chip. | 23736663 | 2013 Aug 7; |
Changes in macrophage phenotype as the immune response evolves. | Lichtnekert, Julia; Kawakami, Takahisa; Parks, William C; Duffield, Jeremy S | Current opinion in pharmacology. | 23747023 | 2013 Aug; |
Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. | Christoforou, Nicolas; Liau, Brian; Chakraborty, Syandan; Chellapan, Malathi; Bursac, Nenad; Leong, Kam W | PloS one. | 23785459 | 2013; |
Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients. | Baker, Brendon M; Trappmann, Britta; Stapleton, Sarah C; Toro, Esteban; Chen, Christopher S | Lab on a chip. | 23787488 | 2013 Aug 21; |
The Dormancy Dilemma: Quiescence versus Balanced Proliferation. | Wells, Alan; Griffith, Linda; Wells, Jakob Z; Taylor, Donald P | Cancer research | 23794703 | 2013 Jun 21 |
Microfluidic heart on a chip for higher throughput pharmacological studies. | Agarwal, Ashutosh; Goss, Josue Adrian; Cho, Alexander; McCain, Megan Laura; Parker, Kevin Kit | Lab on a chip | 23807141 | 2013 Aug 13 |
Scaling and systems biology for integrating multiple organs-on-a-chip. | Wikswo, John P; Curtis, Erica L; Eagleton, Zachary E; Evans, Brian C; Kole, Ayeeshik; Hofmeister, Lucas H; Matloff, William J | Lab on a chip | 23828456 | 2013 Aug 13 |
Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus. | Connor, Jason T; Elm, Jordan J; Broglio, Kristine R; ESETT and ADAPT-IT Investigators | Journal of clinical epidemiology | 23849147 | 2013 Aug |
Spinal Cord Injury Neuroprotection and the Promise of Flexible Adaptive Clinical Trials. | Meurer, William J; Barsan, William G | World neurosurgery | 23851207 | 2013 Jul 9 |
Look back in anger - what clinical studies tell us about preclinical work. | Hartung, Thomas | ALTEX | 23861075 | 2013 |
Expression and functional relevance of UGT1A4 in a cohort of human drug-resistant epileptic brains. | Ghosh, Chaitali; Hossain, Mohammed; Puvenna, Vikram; Martinez-Gonzalez, Jorge; Alexopolous, Andreas; Janigro, Damir; Marchi, Nicola | Epilepsia. | 23865846 | 2013 Sep; |
Rat hepatocyte culture model of macrosteatosis: effect of macrosteatosis induction and reversal on viability and liver-specific function. | Nativ, Nir I; Yarmush, Gabriel; Chen, Alvin; Dong, David; Henry, Scot D; Guarrera, James V; Klein, Kenneth M; Maguire, Tim; Schloss, Rene; Berthiaume, Francois; Yarmush, Martin L | Journal of hepatology. | 23872604 | 2013 Dec; |
Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. | Johnston, S Claiborne; Easton, J Donald; Farrant, Mary; Barsan, William; Battenhouse, Holly; Conwit, Robin; Dillon, Catherine; Elm, Jordan; Lindblad, Anne; Morgenstern, Lewis; Poisson, Sharon N; Palesch, Yuko | International journal of stroke : official journal of the International Stroke Society | 23879752 | 2013 Aug |
Transplantable liver organoids made from only three ingredients. | Willenbring, Holger; Soto-Gutierrez, Alejandro | Cell stem cell. | 23910079 | 2013 Aug 1; |
Characterization of early neovascular response to acute lung ischemia using simultaneous (19)F/ (1)H MR molecular imaging. | Schmieder, Anne H; Wang, Kezheng; Zhang, Huiying; Senpan, Angana; Pan, Dipanjan; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Shen, Baozhong; Wagner, Elizabeth M; Lanza, Gregory M | Angiogenesis | 23918207 | 2014 Jan |
Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. | Hung, Chi; Linn, Geoffrey; Chow, Yu-Hua; Kobayashi, Akio; Mittelsteadt, Kristen; Altemeier, William A; Gharib, Sina A; Schnapp, Lynn M; Duffield, Jeremy S | American journal of respiratory and critical care medicine | 23924232 | 2013 Oct 01 |
A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells. | Magness, Scott T; Puthoff, Brent J; Crissey, Mary Ann; Dunn, James; Henning, Susan J; Houchen, Courtney; Kaddis, John S; Kuo, Calvin J; Li, Linheng; Lynch, John; Martin, Martin G; May, Randal; Niland, Joyce C; Olack, Barbara; Qian, Dajun; Stelzner, Matthi | American journal of physiology. Gastrointestinal and liver physiology. | 23928185 | 2013 Oct 15; |
Bioengineering heart tissue for in vitro testing. | Cimetta, Elisa; Godier-Furnemont, Amandine; Vunjak-Novakovic, Gordana | Current opinion in biotechnology | 23932513 | 2013 Aug 6 |
Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase. | Coulter, Jonathan B; O'Driscoll, Cliona M; Bressler, Joseph P | The Journal of biological chemistry. | 23940045 | 2013 Oct 4; |
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. | Hou, Zhonggang; Zhang, Yan; Propson, Nicholas E; Howden, Sara E; Chu, Li-Fang; Sontheimer, Erik J; Thomson, James A | Proceedings of the National Academy of Sciences of the United States of America. | 23940360 | 2013 Sep 24; |
Clear castable polyurethane elastomer for fabrication of microfluidic devices. | Domansky, Karel; Leslie, Daniel C; McKinney, James; Fraser, Jacob P; Sliz, Josiah D; Hamkins-Indik, Tiama; Hamilton, Geraldine A; Bahinski, Anthony; Ingber, Donald E | Lab on a chip | 23954953 | 2013 Oct 7 |
Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions. | Kawakami, Takahisa; Lichtnekert, Julia; Thompson, Lucas J; Karna, Prasanthi; Bouabe, Hicham; Hohl, Tobias M; Heinecke, Jay W; Ziegler, Steven F; Nelson, Peter J; Duffield, Jeremy S | Journal of immunology (Baltimore, Md. : 1950) | 23956422 | 2013 Sep 15 |
A brief account of nanoparticle contrast agents for photoacoustic imaging. | Pan, Dipanjan; Kim, Benjamin; Wang, Lihong V; Lanza, Gregory M | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 23983210 | 2013 Nov-Dec |
A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches. | Janigro, Damir; Iffland 2nd, Philip H; Marchi, Nicola; Granata, Tiziana | Epilepsia. | 24001067 | 2013 Sep; |
The established status epilepticus trial 2013. | Bleck, Thomas; Cock, Hannah; Chamberlain, James; Cloyd, James; Connor, Jason; Elm, Jordan; Fountain, Nathan; Jones, Elizabeth; Lowenstein, Daniel; Shinnar, Shlomo; Silbergleit, Robert; Treiman, David; Trinka, Eugen; Kapur, Jaideep | Epilepsia | 24001084 | 2013 Sep |
Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix. | Yang, Guang; Rothrauff, Benjamin B; Lin, Hang; Gottardi, Riccardo; Alexander, Peter G; Tuan, Rocky S | Biomaterials. | 24044998 | 2013 Dec; |
Variation in diffusion of gases through PDMS due to plasma surface treatment and storage conditions. | Markov, Dmitry A; Lillie, Elizabeth M; Garbett, Shawn P; McCawley, Lisa J | Biomedical microdevices. | 24065585 | 2014 Feb; |
Femtosecond laser-patterned nanopore arrays for surface-mediated peptide treatment. | Zachman, Angela L; Hofmeister, Lucas H; Costa, Lino; Boire, Timothy C; Hwang, Yu-Shik; Hofmeister, William H; Sung, Hak-Joon | Nanomedicine : nanotechnology, biology, and medicine | 24090768 | 2014 Jan |
Portable bioreactor for perfusion and electrical stimulation of engineered cardiac tissue. | Tandon, Nina; Taubman, Alanna; Cimetta, Elisa; Saccenti, Laetitia; Vunjak-Novakovic, Gordana | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. | 24111161 | 2013; |
Microfabrication of human organs-on-chips. | Huh, Dongeun; Kim, Hyun Jung; Fraser, Jacob P; Shea, Daniel E; Khan, Mohammed; Bahinski, Anthony; Hamilton, Geraldine A; Ingber, Donald E | Nature protocols | 24113786 | 2013 Nov |
Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport. | Yeung, Catherine K; Shen, Danny D; Thummel, Kenneth E; Himmelfarb, Jonathan | Kidney international | 24132209 | 2014 Mar |
Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers. | Fernandez, Cristina E; Obi-onuoha, Izundu C; Wallace, Charles S; Satterwhite, Lisa L; Truskey, George A; Reichert, William M | Acta biomaterialia | 24140604 | 2014 Feb |
Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs). | Itoh, Munenari; Umegaki-Arao, Noriko; Guo, Zongyou; Liu, Liang; Higgins, Claire A; Christiano, Angela M | PloS one. | 24147053 | 2013; |
Microfluidic device to culture 3D in vitro human capillary networks. | Moya, Monica L; Alonzo, Luis F; George, Steven C | Methods in molecular biology (Clifton, N.J.). | 24155229 | 2014; |
Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption. | Singh, Varsha; Yang, Jianbo; Chen, Tiane-e; Zachos, Nicholas C; Kovbasnjuk, Olga; Verkman, Alan S; Donowitz, Mark | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. | 24184676 | 2014 Jan; |
Development of a new method for the isolation and culture of pulmonary arterial endothelial cells from rat pulmonary arteries. | Peng, Gongyong; Wen, Xing; Shi, Yu; Jiang, Yongliang; Hu, Guoping; Zhou, Yumin; Ran, Pixin | Journal of vascular research. | 24192526 | 2013; |
Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles. | Pham, Christine T N; Thomas, Dennis G; Beiser, Julia; Mitchell, Lynne M; Huang, Jennifer L; Senpan, Angana; Hu, Grace; Gordon, Mae; Baker, Nathan A; Pan, Dipanjan; Lanza, Gregory M; Hourcade, Dennis E | Nanomedicine : nanotechnology, biology, and medicine | 24211337 | 2013 Nov 8 |
New immunological approaches in treating and diagnosing CNS diseases. | Guo, Kathy; Janigro, Damir | Pharmaceutical patent analyst | 24237062 | 2013 May |
Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion. | Grahovac, Jelena; Wells, Alan | Laboratory investigation; a journal of technical methods and pathology | 24247562 | 2014 Jan |
Three-dimensional filamentous human diseased cardiac tissue model. | Ma, Zhen; Koo, Sangmo; Finnegan, Micaela A; Loskill, Peter; Huebsch, Nathaniel; Marks, Natalie C; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin E | Biomaterials | 24268663 | 2014 Feb |
Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems. | Hong, Sungmin; Jung, Youngmee; Yen, Ringo; Chan, Hon Fai; Leong, Kam W; Truskey, George A; Zhao, Xuanhe | Lab on a chip. | 24310854 | 2014 Feb 7; |
Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients. | McLaughlin, Bethann; Gidday, Jeff M | Translational stroke research | 24323191 | 2013 Feb |
Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays. | Nguyen, Eric H; Zanotelli, Matthew R; Schwartz, Michael P; Murphy, William L | Biomaterials | 24332391 | 2014 Feb |
Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. | Cheng, Cindy S; El-Abd, Yasser; Bui, Khanh; Hyun, Young-Eun; Hughes, Rebecca Harbuck; Kraus, William E; Truskey, George A | American journal of physiology. Cell physiology | 24336652 | 2014 Feb 15 |
Harnessing localized ridges for high-aspect-ratio hierarchical patterns with dynamic tunability and multifunctionality. | Cao, Changyong; Chan, Hon Fai; Zang, Jianfeng; Leong, Kam W; Zhao, Xuanhe | Advanced materials (Deerfield Beach, Fla.) | 24339233 | 2014 Mar 19 |
Assessing the barriers to image-guided drug delivery. | Lanza, Gregory M; Moonen, Chrit; Baker Jr, James R; Chang, Esther; Cheng, Zheng; Grodzinski, Piotr; Ferrara, Katherine; Hynynen, Kullervo; Kelloff, Gary; Lee, Yong-Eun Koo; Patri, Anil K; Sept, David; Schnitzer, Jan E; Wood, Bradford J; Zhang, Miqin; Zhen | Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology | 24339356 | 2014 Jan-Feb |
Inflammatory pathways of seizure disorders. | Marchi, Nicola; Granata, Tiziana; Janigro, Damir | Trends in neurosciences. | 24355813 | 2014 Feb; |
Physiologically relevant organs on chips. | Yum, Kyungsuk; Hong, Soon Gweon; Healy, Kevin E; Lee, Luke P | Biotechnology journal. | 24357624 | 2014 Jan; |
Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles. | Rangarajan, Swathi; Madden, Lauran; Bursac, Nenad | Annals of biomedical engineering. | 24366526 | 2014 Jul; |
Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy. | Li, Fengqiang; Xu, Ting; Nguyen, Duc-Huy T; Huang, Xiaolei; Chen, Christopher S; Zhou, Chao | Journal of biomedical optics. | 24395588 | 2014 Jan; |
How multi-organ microdevices can help foster drug development. | Esch, Mandy B; Smith, Alec S T; Prot, Jean-Matthieu; Oleaga, Carlota; Hickman, James J; Shuler, Michael L | Advanced drug delivery reviews. | 24412641 | 2014 Apr; |
The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine. | Martins, Ana M; Vunjak-Novakovic, Gordana; Reis, Rui L | Stem cell reviews | 24425421 | 2014 Apr |
Mapping the human toxome by systems toxicology. | Bouhifd, Mounir; Hogberg, Helena T; Kleensang, Andre; Maertens, Alexandra; Zhao, Liang; Hartung, Thomas | Basic & clinical pharmacology & toxicology | 24443875 | 2014 Jul |
Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer. | May, Jody C; Goodwin, Cody R; Lareau, Nichole M; Leaptrot, Katrina L; Morris, Caleb B; Kurulugama, Ruwan T; Mordehai, Alex; Klein, Christian; Barry, William; Darland, Ed; Overney, Gregor; Imatani, Kenneth; Stafford, George C; Fjeldsted, John C; McLean, Jo | Analytical chemistry. | 24446877 | 2014 Feb 18; |
Nanoinformatics workshop report: Current resources, community needs, and the proposal of a collaborative framework for data sharing and information integration. | Harper, Stacey L; Hutchison, James E; Baker, Nathan; Ostraat, Michele; Tinkle, Sally; Steevens, Jeffrey; Hoover, Mark D; Adamick, Jessica; Rajan, Krishna; Gaheen, Sharon; Cohen, Yoram; Nel, Andre; Cachau, Raul E; Tuominen, Mark | Computational science & discovery | 24454543 | 2013 |
Molecular imaging with computed tomography. | Lanza, Gregory M; Pan, Dipanjan | Contrast media & molecular imaging | 24470289 | 2014 Jan-Feb |
Multicolor computed tomographic molecular imaging with noncrystalline high-metal-density nanobeacons. | Pan, Dipanjan; Schirra, Carsten O; Wickline, Samuel A; Lanza, Gregory M | Contrast media & molecular imaging | 24470291 | 2014 Jan-Feb |
Physical influences on stem cells. | Vunjak-Novakovic, Gordana | Stem cell research & therapy. | 24476419 | 2013; |
Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues. | Li, Cheri Yingjie; Stevens, Kelly R; Schwartz, Robert E; Alejandro, Brian Steven; Huang, Joanne H; Bhatia, Sangeeta N | Tissue engineering. Part A | 24498910 | 2014 Feb 5 |
Biological and engineering design considerations for vascular tissue engineered blood vessels (TEBVs). | Fernandez, Cristina E; Achneck, Hardean E; Reichert, William M; Truskey, George A | Current opinion in chemical engineering. | 24511460 | 2014 Feb 1; |
Annotating the structure and components of a nanoparticle formulation using computable string expressions. | Thomas, Dennis G; Chikkagoudar, Satish; Chappell, Alan R; Baker, Nathan A | Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. | 24533226 | 2012 Dec 31; |
Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system. | Kelly, Edward J; Wang, Zhican; Voellinger, Jenna L; Yeung, Cathy K; Shen, Danny D; Thummel, Kenneth E; Zheng, Ying; Ligresti, Giovanni; Eaton, David L; Muczynski, Kimberly A; Duffield, Jeremy S; Neumann, Thomas; Tourovskaia, Anna; Fauver, Mark; Kramer, Gr | Stem cell research & therapy. | 24564863 | 2013; |
Neurovascular unit on a chip: implications for translational applications. | Alcendor, Donald J; Block 3rd, Frank E; Cliffel, David E; Daniels, John Scott; Ellacott, Kate L J; Goodwin, Cody R; Hofmeister, Lucas H; Li, Deyu; Markov, Dmitry A; May, Jody C; McCawley, Lisa J; McLaughlin, BethAnn; McLean, John A; Niswender, Kevin D; Pe | Stem cell research & therapy. | 24564885 | 2013; |
Building a microphysiological skin model from induced pluripotent stem cells. | Guo, Zongyou; Higgins, Claire A; Gillette, Brian M; Itoh, Munenari; Umegaki, Noriko; Gledhill, Karl; Sia, Samuel K; Christiano, Angela M | Stem cell research & therapy. | 24564920 | 2013; |
Human enteroids: preclinical models of non-inflammatory diarrhea. | Kovbasnjuk, Olga; Zachos, Nicholas C; In, Julie; Foulke-Abel, Jennifer; Ettayebi, Khalil; Hyser, Joseph M; Broughman, James R; Zeng, Xi-Lei; Middendorp, Sabine; de Jonge, Hugo R; Estes, Mary K; Donowitz, Mark | Stem cell research & therapy. | 24564938 | 2013; |
Toward a 3D model of human brain development for studying gene/environment interactions. | Hogberg, Helena T; Bressler, Joseph; Christian, Kimberly M; Harris, Georgina; Makri, Georgia; O'Driscoll, Cliona; Pamies, David; Smirnova, Lena; Wen, Zhexing; Hartung, Thomas | Stem cell research & therapy. | 24564953 | 2013; |
Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. | Hartman, Kira G; Bortner, James D; Falk, Gary W; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John P | Stem cell research & therapy. | 24564965 | 2013; |
Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis. | Lozito, Thomas P; Alexander, Peter G; Lin, Hang; Gottardi, Riccardo; Cheng, Anthony Wai-Ming; Tuan, Rocky S | Stem cell research & therapy. | 24564995 | 2013; |
Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology. | Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Cortiella, Joaquin | Stem cell research & therapy. | 24565038 | 2013; |
HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease. | Vunjak-Novakovic, Gordana; Bhatia, Sangeeta; Chen, Christopher; Hirschi, Karen | Stem cell research & therapy | 24565063 | 2013 |
Microphysiological systems and low-cost microfluidic platform with analytics. | Smith, Alec S T; Long, Christopher J; Berry, Bonnie J; McAleer, Christopher; Stancescu, Maria; Molnar, Peter; Miller, Paula G; Esch, Mandy B; Prot, Jean-Matthieu; Hickman, James J; Shuler, Michael L | Stem cell research & therapy. | 24565109 | 2013; |
Building additional complexity to in vitro-derived intestinal tissues. | Brugmann, Samantha A; Wells, James M | Stem cell research & therapy. | 24565179 | 2013; |
Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing. | Truskey, George A; Achneck, Hardean E; Bursac, Nenad; Chan, Hon; Cheng, Cindy S; Fernandez, Cristina; Hong, Sungmin; Jung, Youngmee; Koves, Tim; Kraus, William E; Leong, Kam; Madden, Lauran; Reichert, William M; Zhao, Xuanhe | Stem cell research & therapy. | 24565225 | 2013; |
All-human microphysical model of metastasis therapy. | Wheeler, Sarah E; Borenstein, Jeffrey T; Clark, Amanda M; Ebrahimkhani, Mohammad R; Fox, Ira J; Griffith, Linda; Inman, Walker; Lauffenburger, Douglas; Nguyen, Transon; Pillai, Venkateswaran C; Prantil-Baun, Rachelle; Stolz, Donna B; Taylor, Donald; Ulric | Stem cell research & therapy. | 24565274 | 2013; |
A human pluripotent stem cell platform for assessing developmental neural toxicity screening. | Hou, Zhonggang; Zhang, Jue; Schwartz, Michael P; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James A | Stem cell research & therapy. | 24565336 | 2013; |
Recreating the female reproductive tract in vitro using iPSC technology in a linked microfluidics environment. | Laronda, Monica M; Burdette, Joanna E; Kim, J; Woodruff, Teresa K | Stem cell research & therapy | 24565375 | 2013 |
Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development. | Mathur, Anurag; Loskill, Peter; Hong, Soongweon; Lee, Jae; Marcus, Sivan G; Dumont, Laure; Conklin, Bruce R; Willenbring, Holger; Lee, Luke P; Healy, Kevin E | Stem cell research & therapy. | 24565415 | 2013; |
An integrated in vitro model of perfused tumor and cardiac tissue. | Moya, Monica; Tran, David; George, Steven C | Stem cell research & therapy. | 24565445 | 2013; |
Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans. | Bhushan, Abhinav; Senutovitch, Nina; Bale, Shyam S; McCarty, William J; Hegde, Manjunath; Jindal, Rohit; Golberg, Inna; Berk Usta, O; Yarmush, Martin L; Vernetti, Lawrence; Gough, Albert; Bakan, Ahmet; Shun, Tong Ying; DeBiasio, Richard; Lansing Taylor, D | Stem cell research & therapy. | 24565476 | 2013; |
Mouse liver repopulation with hepatocytes generated from human fibroblasts. | Zhu, Saiyong; Rezvani, Milad; Harbell, Jack; Mattis, Aras N; Wolfe, Alan R; Benet, Leslie Z; Willenbring, Holger; Ding, Sheng | Nature. | 24572354 | 2014 Apr 3; |
Three-dimensional paper-based model for cardiac ischemia. | Mosadegh, Bobak; Dabiri, Borna E; Lockett, Matthew R; Derda, Ratmir; Campbell, Patrick; Parker, Kevin Kit; Whitesides, George M | Advanced healthcare materials. | 24574054 | 2014 Jul; |
Cartilage tissue engineering application of injectable gelatin hydrogel with in situ visible-light-activated gelation capability in both air and aqueous solution. | Lin, Hang; Cheng, Anthony Wai-Ming; Alexander, Peter G; Beck, Angela M; Tuan, Rocky S | Tissue engineering. Part A. | 24575844 | 2014 Sep; |
Cancer Stem Cells under Hypoxia as a Chemoresistance Factor in Breast and Brain. | Crowder, Spencer W; Balikov, Daniel A; Hwang, Yu-Shik; Sung, Hak-Joon | Current pathobiology reports. | 24587979 | 2014 Mar; |
Myocardial tissue engineering: in vitro models. | Vunjak Novakovic, Gordana; Eschenhagen, Thomas; Mummery, Christine | Cold Spring Harbor perspectives in medicine. | 24591534 | 2014 Mar; |
Bioreactor technologies to support liver function in vitro. | Ebrahimkhani, Mohammad R; Neiman, Jaclyn A Shepard; Raredon, Micha Sam B; Hughes, David J; Griffith, Linda G | Advanced drug delivery reviews | 24607703 | 2014 Apr |
Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition. | Taylor, Donald P; Clark, Amanda; Wheeler, Sarah; Wells, Alan | Breast cancer research and treatment | 24610032 | 2014 Apr |
The mitogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase (ERK) are involved in hepatocyte-mediated phenotypic switching in prostate cancer cells. | Ma, Bo; Wells, Alan | The Journal of biological chemistry. | 24619413 | 2014 Apr 18; |
Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor. | Diederichs, Solvig; Tuan, Rocky S | Stem cells and development. | 24625206 | 2014 Jul 15; |
Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening. | Zhao, Ruogang; Chen, Christopher S; Reich, Daniel H | Biomaterials. | 24630092 | 2014 Jun; |
Antagonizing the *v *3 integrin inhibits angiogenesis and impairs woven but not lamellar bone formation induced by mechanical loading. | Tomlinson, Ryan E; Schmieder, Anne H; Quirk, James D; Lanza, Gregory M; Silva, Matthew J | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. | 24644077 | 2014 Sep; |
Engineering Liver. | Griffith, Linda G; Wells, Alan; Stolz, Donna Beer | Hepatology (Baltimore, Md.) | 24668880 | 2014 Mar 26 |
Quality metrics for stem cell-derived cardiac myocytes. | Sheehy, Sean P; Pasqualini, Francesco; Grosberg, Anna; Park, Sung Jin; Aratyn-Schaus, Yvonne; Parker, Kevin Kit | Stem cell reports. | 24672752 | 2014 Mar 11; |
Structural characterization of methylenedianiline regioisomers by ion mobility-mass spectrometry, tandem mass spectrometry, and computational strategies: I. Electrospray spectra of 2-ring isomers. | Forsythe, Jay G; Stow, Sarah M; Nefzger, Hartmut; Kwiecien, Nicholas W; May, Jody C; McLean, John A; Hercules, David M | Analytical chemistry. | 24678803 | 2014 May 6; |
Matrix elasticity regulates the optimal cardiac myocyte shape for contractility. | McCain, Megan L; Yuan, Hongyan; Pasqualini, Francesco S; Campbell, Patrick H; Parker, Kevin Kit | American journal of physiology. Heart and circulatory physiology. | 24682394 | 2014 Jun 1; |
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities. | Smirnova, Lena; Hogberg, Helena T; Leist, Marcel; Hartung, Thomas | ALTEX | 24687333 | 2014 |
The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. | Kulangara, Karina; Adler, Andrew F; Wang, Hong; Chellappan, Malathi; Hammett, Ellen; Yasuda, Ryohei; Leong, Kam W | Biomaterials. | 24709523 | 2014 Jul; |
Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract. | Foulke-Abel, Jennifer; In, Julie; Kovbasnjuk, Olga; Zachos, Nicholas C; Ettayebi, Khalil; Blutt, Sarah E; Hyser, Joseph M; Zeng, Xi-Lei; Crawford, Sue E; Broughman, James R; Estes, Mary K; Donowitz, Mark | Experimental biology and medicine (Maywood, N.J.). | 24719375 | 2014 Sep; |
3D - a new dimension of in vitro research. | Hartung, Thomas | Advanced drug delivery reviews. | 24721291 | 2014 Apr; |
Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using *(v)*ýýý-targeted theranostic nanoparticles. | Pan, Dipanjan; Schmieder, Anne H; Wang, Kezheng; Yang, Xiaoxia; Senpan, Angana; Cui, Grace; Killgore, Kendall; Kim, Benjamin; Allen, John S; Zhang, Huiying; Caruthers, Shelton D; Shen, Baozhong; Wickline, Samuel A; Lanza, Gregory M | Theranostics | 24723979 | 2014 |
Integrating in vitro organ-specific function with the microcirculation. | Moya, Monica L; George, Steven C | Current opinion in chemical engineering. | 24729953 | 2014 Feb 1; |
Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues. | McCain, Megan L; Agarwal, Ashutosh; Nesmith, Haley W; Nesmith, Alexander P; Parker, Kevin Kit | Biomaterials. | 24731714 | 2014 Jul; |
Microscale technologies for regulating human stem cell differentiation. | Cimetta, Elisa; Vunjak-Novakovic, Gordana | Experimental biology and medicine (Maywood, N.J.). | 24737735 | 2014 Sep; |
Microphysiological modeling of the reproductive tract: A fertile endeavor. | Eddie, Sharon L; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna E | Experimental biology and medicine (Maywood, N.J.) | 24737736 | 2014 Apr 15 |
A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening. | Heylman, Christopher; Sobrino, Agua; Shirure, Venktesh S; Hughes, Christopher Cw; George, Steven C | Experimental biology and medicine (Maywood, N.J.). | 24740872 | 2014 Sep; |
Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKC? signaling. | Cha, Boyoung; Chen, Tiane; Sarker, Rafiquel; Yang, Jianbo; Raben, Daniel; Tse, C Ming; Kovbasnjuk, Olga; Donowitz, Mark | American journal of physiology. Cell physiology. | 24760985 | 2014 Jul 1; |
A three-dimensional in vitro model of tumor cell intravasation. | Ehsan, Seema M; Welch-Reardon, Katrina M; Waterman, Marian L; Hughes, Christopher C W; George, Steven C | Integrative biology : quantitative biosciences from nano to macro. | 24763498 | 2014 Jun; |
In vitro platforms for evaluating liver toxicity. | Bale, Shyam Sundhar; Vernetti, Lawrence; Senutovitch, Nina; Jindal, Rohit; Hegde, Manjunath; Gough, Albert; McCarty, William J; Bakan, Ahmet; Bhushan, Abhinav; Shun, Tong Y; Golberg, Inna; DeBiasio, Richard; Usta, O Berk; Taylor, D Lansing; Yarmush, Marti | Experimental biology and medicine (Maywood, N.J.). | 24764241 | 2014 Sep; |
Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research. | Abrams, Julian A; Appelman, Henry D; Beer, David G; Berry, Lynne D; Chak, Amitabh; Falk, Gary W; Fitzgerald, Rebecca C; Ginsberg, Gregory G; Grady, William M; Joshi, Bishnu P; Lynch, John P; Markowitz, Sanford; Richmond, Ellen S; Rustgi, Anil K; Seibel, E | Gastroenterology. | 24768332 | 2014 Jun; |
Dynamic interplay of flow and collagen stabilizes primary hepatocytes culture in a microfluidic platform. | Hegde, Manjunath; Jindal, Rohit; Bhushan, Abhinav; Bale, Shyam Sundhar; McCarty, William J; Golberg, Inna; Usta, O Berk; Yarmush, Martin L | Lab on a chip. | 24770663 | 2014 Jun 21; |
Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems. | Hartman, Kira G; Bortner Jr, James D; Falk, Gary W; Ginsberg, Gregory G; Jhala, Nirag; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John P | Experimental biology and medicine (Maywood, N.J.). | 24781339 | 2014 Sep; |
Approaches to in vitro tissue regeneration with application for human disease modeling and drug development. | Ebrahimkhani, Mohammad R; Young, Carissa L; Lauffenburger, Douglas A; Griffith, Linda G; Borenstein, Jeffrey T | Drug discovery today | 24793141 | 2014 Jun |
Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits. | Puvenna, Vikram; Brennan, Chanda; Shaw, Gerald; Yang, Cui; Marchi, Nicola; Bazarian, Jeffrey J; Merchant-Borna, Kian; Janigro, Damir | PloS one. | 24806476 | 2014; |
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. | Wang, Gang; McCain, Megan L; Yang, Luhan; He, Aibin; Pasqualini, Francesco Silvio; Agarwal, Ashutosh; Yuan, Hongyan; Jiang, Dawei; Zhang, Donghui; Zangi, Lior; Geva, Judith; Roberts, Amy E; Ma, Qing; Ding, Jian; Chen, Jinghai; Wang, Da-Zhi; Li, Kai; Wang, | Nature medicine. | 24813252 | 2014 Jun; |
Materials innovation for co-delivery of diverse therapeutic cargos. | Godsey, Megan E; Suryaprakash, Smruthi; Leong, Kam W | RSC advances. | 24818000 | 2013 Dec 21; |
Polymeric stent materials dysregulate macrophage and endothelial cell functions: implications for coronary artery stent. | Wang, Xintong; Zachman, Angela L; Chun, Young Wook; Shen, Fang-Wen; Hwang, Yu-Shik; Sung, Hak-Joon | International journal of cardiology. | 24820736 | 2014 Jul 1; |
A microphysiological system model of therapy for liver micrometastases. | Clark, Amanda M; Wheeler, Sarah E; Taylor, Donald P; Pillai, Venkateswaran C; Young, Carissa L; Prantil-Baun, Rachelle; Nguyen, Transon; Stolz, Donna B; Borenstein, Jeffrey T; Lauffenburger, Douglas A; Venkataramanan, Raman; Griffith, Linda G; Wells, Alan | Experimental biology and medicine (Maywood, N.J.). | 24821820 | 2014 Sep; |
Approaching the in vitro clinical trial: engineering organs on chips. | Capulli, A K; Tian, K; Mehandru, N; Bukhta, A; Choudhury, S F; Suchyta, M; Parker, K K | Lab on a chip. | 24828385 | 2014 Sep 7; |
Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1?. | Lin, Hang; Lozito, Thomas P; Alexander, Peter G; Gottardi, Riccardo; Tuan, Rocky S | Molecular pharmaceutics. | 24830762 | 2014 Jul 7; |
MR cholangiography demonstrates unsuspected rapid biliary clearance of nanoparticles in rodents: implications for clinical translation. | Bulte, Jeff W M; Schmieder, Anne H; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory M | Nanomedicine : nanotechnology, biology, and medicine. | 24832959 | 2014 Oct; |
Multi-scale multi-mechanism design of tough hydrogels: building dissipation into stretchy networks. | Zhao, Xuanhe | Soft matter. | 24834901 | 2014 Feb 7; |
Intracerebral hemorrhage mortality is not changing despite declining incidence. | Zahuranec, Darin B; Lisabeth, Lynda D; Sanchez, Brisa N; Smith, Melinda A; Brown, Devin L; Garcia, Nelda M; Skolarus, Lesli E; Meurer, William J; Burke, James F; Adelman, Eric E; Morgenstern, Lewis B | Neurology | 24838789 | 2014 Jun 17 |
Fluid shear stress threshold regulates angiogenic sprouting. | Galie, Peter A; Nguyen, Duc-Huy T; Choi, Colin K; Cohen, Daniel M; Janmey, Paul A; Chen, Christopher S | Proceedings of the National Academy of Sciences of the United States of America | 24843171 | 2014 Jun 3 |
Ovarian cancer in endometriosis: clinical and molecular aspects. | Lyttle, B; Bernardi, L; Pavone, M E | Minerva ginecologica | 24848074 | 2014 Apr |
Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury. | Chen, Yi-Ting; Chang, Yu-Ting; Pan, Szu-Yu; Chou, Yu-Hsiang; Chang, Fan-Chi; Yeh, Pei-Ying; Liu, Yuan-Hung; Chiang, Wen-Chih; Chen, Yung-Ming; Wu, Kwan-Dun; Tsai, Tun-Jun; Duffield, Jeremy S; Lin, Shuei-Liong | Journal of the American Society of Nephrology : JASN | 24854266 | 2014 Dec |
Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. | Evans, J Corey; Hines, Kelly M; Forsythe, Jay G; Erdogan, Begum; Shi, Mingjian; Hill, Salisha; Rose, Kristie L; McLean, John A; Webb, Donna J | Journal of proteome research. | 24874604 | 2014 Jul 3; |
Cellular and molecular mechanisms in kidney fibrosis. | Duffield, Jeremy S | The Journal of clinical investigation | 24892703 | 2014 Jun |
Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems. | Marasco, Christina C; Goodwin, Cody R; Winder, Danny G; Schramm-Sapyta, Nicole L; McLean, John A; Wikswo, John P | Experimental biology and medicine (Maywood, N.J.). | 24903164 | 2014 Nov; |
Induced pluripotent stem cells for regenerative medicine. | Hirschi, Karen K; Li, Song; Roy, Krishnendu | Annual review of biomedical engineering. | 24905879 | 2014 Jul 11; |
A multiplexed chip-based assay system for investigating the functional development of human skeletal myotubes in vitro. | Smith, A S T; Long, C J; Pirozzi, K; Najjar, S; McAleer, C; Vandenburgh, H H; Hickman, J J | Journal of biotechnology. | 24909944 | 2014 Sep 20; |
Improved Coarse-Grained Modeling of Cholesterol-Containing Lipid Bilayers. | Daily, Michael D; Olsen, Brett N; Schlesinger, Paul H; Ory, Daniel S; Baker, Nathan A | Journal of chemical theory and computation. | 24910542 | 2014 May 13; |
Biological and medical applications of a brain-on-a-chip. | Pamies, David; Hartung, Thomas; Hogberg, Helena T | Experimental biology and medicine (Maywood, N.J.). | 24912505 | 2014 Sep; |
Physiology and metabolism of tissue-engineered skeletal muscle. | Cheng, Cindy S; Davis, Brittany N J; Madden, Lauran; Bursac, Nenad; Truskey, George A | Experimental biology and medicine (Maywood, N.J.). | 24912506 | 2014 Sep; |
A novel ultrathin collagen nanolayer assembly for 3-D microtissue engineering: Layer-by-layer collagen deposition for long-term stable microfluidic hepatocyte culture. | McCarty, William J; Usta, O Berk; Luitje, Martha; Bale, Shyam Sundhar; Bhushan, Abhinav; Hegde, Manjunath; Golberg, Inna; Jindal, Rohit; Yarmush, Martin L | Technology. | 24932459 | 2014 Mar; |
Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide. | Zhou, Hui-fang; Yan, Huimin; Hu, Ying; Springer, Luke E; Yang, Xiaoxia; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T N | ACS nano | 24941020 | 2014 Jul 22 |
Challenges and promises in modeling dermatologic disorders with bioengineered skin. | Eungdamrong, Narat J; Higgins, Claire; Guo, Zongyou; Lee, Wen-Han; Gillette, Brian; Sia, Samuel; Christiano, Angela M | Experimental biology and medicine (Maywood, N.J.). | 24951469 | 2014 Sep; |
Using physiologically-based pharmacokinetic-guided ''body-on-a-chip'' systems to predict mammalian response to drug and chemical exposure. | Sung, Jong Hwan; Srinivasan, Balaji; Esch, Mandy Brigitte; McLamb, William T; Bernabini, Catia; Shuler, Michael L; Hickman, James J | Experimental biology and medicine (Maywood, N.J.). | 24951471 | 2014 Sep; |
Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use. | Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Argueta, Lissenya B; Eastaway, Adriene; Cortiella, Joaquin | Experimental biology and medicine (Maywood, N.J.). | 24962174 | 2014 Sep; |
Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury. | Esch, Mandy B; Mahler, Gretchen J; Stokol, Tracy; Shuler, Michael L | Lab on a chip. | 24970651 | 2014 Aug 21; |
Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases. | Alexander, Peter G; Gottardi, Riccardo; Lin, Hang; Lozito, Thomas P; Tuan, Rocky S | Experimental biology and medicine (Maywood, N.J.). | 24994814 | 2014 Sep; |
What non-neuronal mechanisms should be studied to understand epileptic seizures? | Janigro, Damir; Walker, Matthew C | Advances in experimental medicine and biology | 25012382 | 2014 |
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. | Alépée, Natalie; Bahinski, Anthony; Daneshian, Mardas; De Wever, Bart; Fritsche, Ellen; Goldberg, Alan; Hansmann, Jan; Hartung, Thomas; Haycock, John; Hogberg, Helena; Hoelting, Lisa; Kelm, Jens M; Kadereit, Suzanne; McVey, Emily; Landsiedel, Robert; Leis | ALTEX. | 25027500 | 2014; |
Tissue-engineered microenvironment systems for modeling human vasculature. | Tourovskaia, Anna; Fauver, Mark; Kramer, Gregory; Simonson, Sara; Neumann, Thomas | Experimental biology and medicine (Maywood, N.J.). | 25030480 | 2014 Sep; |
Cell and tissue engineering for liver disease. | Bhatia, Sangeeta N; Underhill, Gregory H; Zaret, Kenneth S; Fox, Ira J | Science translational medicine | 25031271 | 2014 Jul 16 |
Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery. | Gough, Albert H; Chen, Ning; Shun, Tong Ying; Lezon, Timothy R; Boltz, Robert C; Reese, Celeste E; Wagner, Jacob; Vernetti, Lawrence A; Grandis, Jennifer R; Lee, Adrian V; Stern, Andrew M; Schurdak, Mark E; Taylor, D Lansing | PloS one. | 25036749 | 2014; |
Developing microphysiological systems for use as regulatory tools--challenges and opportunities. | Andersen, Melvin E; Betts, Kellyn; Dragan, Yvonne; Fitzpatrick, Suzanne; Goodman, Jesse L; Hartung, Thomas; Himmelfarb, Jonathan; Ingber, Donald E; Jacobs, Abigail; Kavlock, Robert; Kolaja, Kyle; Stevens, James L; Tagle, Dan; Lansing Taylor, D; Throckmort | ALTEX. | 25061900 | 2014; |
Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes. | Freytes, Donald O; O'Neill, John D; Duan-Arnold, Yi; Wrona, Emily A; Vunjak-Novakovic, Gordana | Methods in molecular biology (Clifton, N.J.). | 25070328 | 2014; |
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. | Shlomai, Amir; Schwartz, Robert E; Ramanan, Vyas; Bhatta, Ankit; de Jong, Ype P; Bhatia, Sangeeta N; Rice, Charles M | Proceedings of the National Academy of Sciences of the United States of America. | 25092305 | 2014 Aug 19; |
Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation. | Nesmith, Alexander Peyton; Agarwal, Ashutosh; McCain, Megan Laura; Parker, Kevin Kit | Lab on a chip | 25093641 | 2014 Oct 21 |
IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study. | Wathen, Connor; Janigro, Damir | Epilepsia | 25099305 | 2014 Aug |
The role of mechanotransduction on vascular smooth muscle myocytes' [corrected] cytoskeleton and contractile function. | Ye, George J C; Nesmith, Alexander P; Parker, Kevin Kit | Anatomical record (Hoboken, N.J. : 2007) | 25125187 | 2014 Sep |
Current progress in Reactive Oxygen Species (ROS)-Responsive materials for biomedical applications. | Lee, Sue Hyun; Gupta, Mukesh K; Bang, Jae Beum; Bae, Hojae; Sung, Hak-Joon | Advanced healthcare materials. | 25136729 | 2013; |
Angiogenesis and airway reactivity in asthmatic Brown Norway rats. | Wagner, Elizabeth M; Jenkins, John; Schmieder, Anne; Eldridge, Lindsey; Zhang, Qiong; Moldobaeva, Aigul; Zhang, Huiying; Allen, John S; Yang, Xiaoxia; Mitzner, Wayne; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory M | Angiogenesis. | 25149641 | 2015 Jan; |
Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels. | Zachman, Angela L; Wang, Xintong; Tucker-Schwartz, Jason M; Fitzpatrick, Sean T; Lee, Sue H; Guelcher, Scott A; Skala, Melissa C; Sung, Hak-Joon | Biomaterials | 25154665 | 2014 Dec |
Balanced UTE-SSFP for 19F MR imaging of complex spectra. | Goette, Matthew J; Keupp, Jochen; Rahmer, Jürgen; Lanza, Gregory M; Wickline, Samuel A; Caruthers, Shelton D | Magnetic resonance in medicine. | 25163853 | 2015 Aug; |
Bond-specific dissociation following excitation energy transfer for distance constraint determination in the gas phase. | Hendricks, Nathan G; Lareau, Nichole M; Stow, Sarah M; McLean, John A; Julian, Ryan R | Journal of the American Chemical Society | 25174489 | 2014 Sep 24 |
Design of growth factor sequestering biomaterials. | Belair, David G; Le, Ngoc Nhi; Murphy, William L | Chemical communications (Cambridge, England). | 25182455 | 2014 Dec 25; |
The relevance and potential roles of microphysiological systems in biology and medicine. | Wikswo, John P | Experimental biology and medicine (Maywood, N.J.) | 25187571 | 2014 Sep |
Human vascular tissue models formed from human induced pluripotent stem cell derived endothelial cells. | Belair, David G; Whisler, Jordan A; Valdez, Jorge; Velazquez, Jeremy; Molenda, James A; Vickerman, Vernella; Lewis, Rachel; Daigh, Christine; Hansen, Tyler D; Mann, David A; Thomson, James A; Griffith, Linda G; Kamm, Roger D; Schwartz, Michael P; Murphy, William L | Stem cell reviews and reports | 25190668 | 2015 Jun |
Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases. | Hines, Kelly M; Ballard, Billy R; Marshall, Dana R; McLean, John A | Molecular bioSystems. | 25212505 | 2014 Nov; |
Long-term coculture strategies for primary hepatocytes and liver sinusoidal endothelial cells. | Bale, Shyam Sundhar; Golberg, Inna; Jindal, Rohit; McCarty, William J; Luitje, Martha; Hegde, Manjunath; Bhushan, Abhinav; Usta, Osman Berk; Yarmush, Martin L | Tissue engineering. Part C, Methods | 25233394 | 2015 Apr |
Physicochemical signatures of nanoparticle-dependent complement activation. | Thomas, Dennis G; Chikkagoudar, Satish; Heredia-Langer, Alejandro; Tardiff, Mark F; Xu, Zhixiang; Hourcade, Dennis E; Pham, Christine T N; Lanza, Gregory M; Weinberger, Kilian Q; Baker, Nathan A | Computational science & discovery. | 25254068 | 2014 Mar 21; |
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. | Spencer, C Ian; Baba, Shiro; Nakamura, Kenta; Hua, Ethan A; Sears, Marie A F; Fu, Chi-cheng; Zhang, Jianhua; Balijepalli, Sadguna; Tomoda, Kiichiro; Hayashi, Yohei; Lizarraga, Paweena; Wojciak, Julianne; Scheinman, Melvin M; Aalto-Setälä, Katriina; Makiel | Stem cell reports. | 25254341 | 2014 Aug 12; |
Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression. | Boussadia, B; Ghosh, C; Plaud, C; Pascussi, J M; de Bock, F; Rousset, M C; Janigro, D; Marchi, N | Neuroscience. | 25280786 | 2014 Oct 2; |
The magic touch: endothelial cells muscle-up adipose. | Martin, Kathleen A; Hirschi, Karen K | Circulation research. | 25301822 | 2014 Oct 10; |
A DNA-based molecular probe for optically reporting cellular traction forces. | Blakely, Brandon L; Dumelin, Christoph E; Trappmann, Britta; McGregor, Lynn M; Choi, Colin K; Anthony, Peter C; Duesterberg, Van K; Baker, Brendon M; Block, Steven M; Liu, David R; Chen, Christopher S | Nature methods. | 25306545 | 2014 Dec; |
Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells. | Coskun, Suleyman; Chao, Hsu; Vasavada, Hema; Heydari, Kartoosh; Gonzales, Naomi; Zhou, Xin; de Crombrugghe, Benoit; Hirschi, Karen K | Cell reports. | 25310984 | 2014 Oct 23; |
Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system. | Wheeler, S E; Clark, A M; Taylor, D P; Young, C L; Pillai, V C; Stolz, D B; Venkataramanan, R; Lauffenburger, D; Griffith, L; Wells, A | British journal of cancer. | 25314052 | 2014 Dec 9; |
On-demand hierarchical patterning with electric fields. | Wang, Qiming; Robinson, Dominick; Zhao, Xuanhe | Applied physics letters. | 25316923 | 2014 Jun 09; |
An in vivo model of human small intestine using pluripotent stem cells. | Watson, Carey L; Mahe, Maxime M; Múnera, Jorge; Howell, Jonathan C; Sundaram, Nambirajan; Poling, Holly M; Schweitzer, Jamie I; Vallance, Jefferson E; Mayhew, Christopher N; Sun, Ying; Grabowski, Gregory; Finkbeiner, Stacy R; Spence, Jason R; Shroyer, Noa | Nature medicine. | 25326803 | 2014 Nov; |
Macrophages modulate engineered human tissues for enhanced vascularization and healing. | Spiller, Kara L; Freytes, Donald O; Vunjak-Novakovic, Gordana | Annals of biomedical engineering | 25331098 | 2015 Mar |
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales. | Huebsch, Nathaniel; Loskill, Peter; Mandegar, Mohammad A; Marks, Natalie C; Sheehan, Alice S; Ma, Zhen; Mathur, Anurag; Nguyen, Trieu N; Yoo, Jennie C; Judge, Luke M; Spencer, C Ian; Chukka, Anand C; Russell, Caitlin R; So, Po-Lin; Conklin, Bruce R; Healy | Tissue engineering. Part C, Methods. | 25333967 | 2015 May; |
ROS-cleavable proline oligomer crosslinking of polycaprolactone for pro-angiogenic host response. | Lee, Sue Hyun; Boire, Timothy C; Lee, Jung Bok; Gupta, Mukesh K; Zachman, Angela L; Rath, Rutwik; Sung, Hak-Joon | Journal of materials chemistry. B, Materials for biology and medicine. | 25343029 | 2014 Nov 7; |
Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia. | Brown, Jacquelyn A; Sherrod, Stacy D; Goodwin, Cody R; Brewer, Bryson; Yang, Lijie; Garbett, Krassimira A; Li, Deyu; McLean, John A; Wikswo, John P; Mirnics, Károly | Journal of neuroinflammation. | 25374324 | 2014; |
Photopatterning of hydrogel scaffolds coupled to filter materials using stereolithography for perfused 3D culture of hepatocytes. | Neiman, Jaclyn A Shepard; Raman, Ritu; Chan, Vincent; Rhoads, Mary G; Raredon, Micha Sam B; Velazquez, Jeremy J; Dyer, Rachel L; Bashir, Rashid; Hammond, Paula T; Griffith, Linda G | Biotechnology and bioengineering. | 25384798 | 2015 Apr; |
Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and nontumorigenic human mesenchymal cell types. | Hansen, Tyler D; Koepsel, Justin T; Le, Ngoc Nhi; Nguyen, Eric H; Zorn, Stefan; Parlato, Matthew; Loveland, Samuel G; Schwartz, Michael P; Murphy, William L | Biomaterials science. | 25386339 | 2014 May; |
Patterning vascular networks in vivo for tissue engineering applications. | Chaturvedi, Ritika R; Stevens, Kelly R; Solorzano, Ricardo D; Schwartz, Robert E; Eyckmans, Jeroen; Baranski, Jan D; Stapleton, Sarah Chase; Bhatia, Sangeeta N; Chen, Christopher S | Tissue engineering. Part C, Methods. | 25390971 | 2015 May; |
Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS. | Kawakami, Takahisa; Gomez, Ivan G; Ren, Shuyu; Hudkins, Kelly; Roach, Allie; Alpers, Charles E; Shankland, Stuart J; D'Agati, Vivette D; Duffield, Jeremy S | Journal of the American Society of Nephrology : JASN | 25406339 | 2015 May |
Wavelet-based peak detection and a new charge inference procedure for MS/MS implemented in ProteoWizard's msConvert. | French, William R; Zimmerman, Lisa J; Schilling, Birgit; Gibson, Bradford W; Miller, Christine A; Townsend, R Reid; Sherrod, Stacy D; Goodwin, Cody R; McLean, John A; Tabb, David L | Journal of proteome research. | 25411686 | 2015 Feb 6; |
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways. | Gomez, Ivan G; MacKenna, Deidre A; Johnson, Bryce G; Kaimal, Vivek; Roach, Allie M; Ren, Shuyu; Nakagawa, Naoki; Xin, Cuiyan; Newitt, Rick; Pandya, Shweta; Xia, Tai-He; Liu, Xueqing; Borza, Dorin-Bogdan; Grafals, Monica; Shankland, Stuart J; Himmelfarb, J | The Journal of clinical investigation. | 25415439 | 2015 Jan; |
A CRISPR/Cas9-based system for reprogramming cell lineage specification. | Chakraborty, Syandan; Ji, HaYeun; Kabadi, Ami M; Gersbach, Charles A; Christoforou, Nicolas; Leong, Kam W | Stem cell reports. | 25448066 | 2014 Dec 9; |
Ion mobility-mass spectrometry strategies for untargeted systems, synthetic, and chemical biology. | May, Jody C; Goodwin, Cody R; McLean, John A | Current opinion in biotechnology. | 25462629 | 2015 Feb; |
Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers. | Wang, Hailong; Abhilash, A S; Chen, Christopher S; Wells, Rebecca G; Shenoy, Vivek B | Biophysical journal. | 25468338 | 2014 Dec 2; |
Tenascin-C Signaling in melanoma. | Shao, Hanshuang; Kirkwood, John M; Wells, Alan | Cell adhesion & migration. | 25482624 | 2015; |
Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts. | Xing, Qi; Vogt, Caleb; Leong, Kam W; Zhao, Feng | Advanced functional materials. | 25484849 | 2014 May 28; |
Correction of dystrophin expression in cells from duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases. | Ousterout, David G; Kabadi, Ami M; Thakore, Pratiksha I; Perez-Pinera, Pablo; Brown, Matthew T; Majoros, William H; Reddy, Timothy E; Gersbach, Charles A | Molecular therapy : the journal of the American Society of Gene Therapy. | 25492562 | 2015 Mar; |
Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis. | Chakraborty, Syandan; Ji, HaYeun; Chen, Jack; Gersbach, Charles A; Leong, Kam W | Scientific reports. | 25492703 | 2014; |
Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain. | Kabadi, Ami M; Thakore, Pratiksha I; Vockley, Christopher M; Ousterout, David G; Gibson, Tyler M; Guilak, Farshid; Reddy, Timothy E; Gersbach, Charles A | ACS synthetic biology. | 25494287 | 2015 Jun 19; |
Nanotopography alters nuclear protein expression, proliferation and differentiation of human mesenchymal stem/stromal cells. | Kulangara, Karina; Yang, Jennifer; Chellappan, Malathi; Yang, Yong; Leong, Kam W | PloS one. | 25521962 | 2014; |
Ion mobility-mass spectrometry: time-dispersive instrumentation. | May, Jody C; McLean, John A | Analytical chemistry. | 25526595 | 2015 Feb 3; |
Three-dimensional modeling of the human fallopian tube fimbriae. | Eddie, Sharon L; Quartuccio, Suzanne M; Zhu, Jie; Shepherd, Jessica A; Kothari, Rajul; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna E | Gynecologic oncology. | 25527363 | 2015 Feb; |
Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. | Warita, Katsuhiko; Warita, Tomoko; Beckwitt, Colin H; Schurdak, Mark E; Vazquez, Alexei; Wells, Alan; Oltvai, Zoltán N | Scientific reports. | 25534349 | 2014; |
Origin and function of cartilage stem/progenitor cells in osteoarthritis. | Jiang, Yangzi; Tuan, Rocky S | Nature reviews. Rheumatology. | 25536487 | 2015 Apr; |
ýýýý*ýýý-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment. | Zhang, Ruiying; Pan, Dipanjan; Cai, Xin; Yang, Xiaoxia; Senpan, Angana; Allen, John S; Lanza, Gregory M; Wang, Lihong V | Theranostics. | 25553103 | 2015; |
Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. | Vega, Maria E; Giroux, Véronique; Natsuizaka, Mitsuteru; Liu, Mingen; Klein-Szanto, Andres J; Stairs, Douglas B; Nakagawa, Hiroshi; Wang, Kenneth K; Wang, Timothy C; Lynch, John P; Rustgi, Anil K | Cell cycle (Georgetown, Tex.). | 25558829 | 2014; |
Nanograting structure promotes lamellipodia-based cell collective migration and wound healing. | Chen, Zaozao; Atchison, Leigh; Ji, HaYeun; Leong, Kam W | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. | 25570601 | 2014; |
Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease. | Wilkerson, Irene; Laban, Joshua; Mitchell, Johnathan M; Sheibani, Nader; Alcendor, Donald J | Journal of neuroinflammation. | 25573478 | 2015; |
Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs. | Madden, Lauran; Juhas, Mark; Kraus, William E; Truskey, George A; Bursac, Nenad | eLife. | 25575180 | 2015; |
Biology coming full circle: joining the whole and the parts. | Wikswo, John P; Porter, Andrew P | Experimental biology and medicine (Maywood, N.J.). | 25583953 | 2015 Jan; |
TEER measurement techniques for in vitro barrier model systems. | Srinivasan, Balaji; Kolli, Aditya Reddy; Esch, Mandy Brigitte; Abaci, Hasan Erbil; Shuler, Michael L; Hickman, James J | Journal of laboratory automation. | 25586998 | 2015 Apr; |
Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair. | Jackman, Christopher P; Shadrin, Ilya Y; Carlson, Aaron L; Bursac, Nenad | Current opinion in chemical engineering. | 25599018 | 2015 Feb; |
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. | Kumar, Kevin K; Goodwin, Cody R; Uhouse, Michael A; Bornhorst, Julia; Schwerdtle, Tanja; Aschner, Michael; McLean, John A; Bowman, Aaron B | Metallomics : integrated biometal science. | 25599126 | 2015 Feb; |
A strategy for combating melanoma with oncogenic c-Myc inhibitors and targeted nanotherapy. | Pan, Dipanjan; Kim, Benjamin; Hu, Grace; Gupta, Deepti Sood; Senpan, Angana; Yang, Xiaoxia; Schmieder, Anne; Swain, Corban; Wickline, Samuel A; Tomasson, Michael H; Lanza, Gregory M | Nanomedicine (London, England). | 25600969 | 2015 Jan; |
Bioengineered tumors. | Villasante, Aranzazu; Vunjak-Novakovic, Gordana | Bioengineered | 25616977 | 2015 |
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes. | Bal-Price, Anna; Crofton, Kevin M; Leist, Marcel; Allen, Sandra; Arand, Michael; Buetler, Timo; Delrue, Nathalie; FitzGerald, Rex E; Hartung, Thomas; Heinonen, Tuula; Hogberg, Helena; Bennekou, Susanne Hougaard; Lichtensteiger, Walter; Oggier, Daniela; Pa | Archives of toxicology. | 25618548 | 2015 Feb; |
Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells. | Furukawa, Masashi; Wheeler, Sarah; Clark, Amanda M; Wells, Alan | PloS one. | 25635394 | 2015; |
Novel three dimensional human endocervix cultures respond to 28-day hormone treatment. | Arslan, Sevim Yildiz; Yu, Yanni; Burdette, Joanne E; Pavone, Mary Ellen; Hope, Thomas J; Woodruff, Teresa K; Kim, J Julie | Endocrinology. | 25635622 | 2015 Apr; |
Developmental biology. Regional identity of gut stem cells--one gene to rule them all. | Wells, James M | Nature reviews. Gastroenterology & hepatology. | 25645971 | 2015 Mar; |
Synergy between surface and core entrapped metals in a mixed manganese-gadolinium nanocolloid affords safer MR imaging of sparse biomarkers. | Wang, Kezheng; Pan, Dipanjan; Schmieder, Anne H; Senpan, Angana; Hourcade, Dennis E; Pham, Christine T N; Mitchell, Lynne M; Caruthers, Shelton D; Cui, Grace; Wickline, Samuel A; Shen, Baozhong; Lanza, Gregory M | Nanomedicine : nanotechnology, biology, and medicine. | 25652900 | 2015 Apr; |
Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study. | Ghosh, Chaitali; Hossain, Mohammad; Spriggs, Addison; Ghosh, Arnab; Grant, Gerald A; Marchi, Nicola; Perucca, Emilio; Janigro, Damir | Epilepsia. | 25656284 | 2015 Mar; |
Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro. | Ng, Shengyong; Schwartz, Robert E; March, Sandra; Galstian, Ani; Gural, Nil; Shan, Jing; Prabhu, Mythili; Mota, Maria M; Bhatia, Sangeeta N | Stem cell reports. | 25660406 | 2015 Mar 10; |
CXCR3 in carcinoma progression. | Ma, Bo; Khazali, Ahmad; Wells, Alan | Histology and histopathology. | 25663474 | 2015 Jul; |
S100B blood levels and childhood trauma in adolescent inpatients. | Falcone, Tatiana; Janigro, Damir; Lovell, Rachel; Simon, Barry; Brown, Charles A; Herrera, Mariela; Myint, Aye Mu; Anand, Amit | Journal of psychiatric research. | 25669696 | 2015 Mar; |
Charge Relaxation Dynamics of an Electrolytic Nanocapacitor. | Thakore, Vaibhav; Hickman, James J | The journal of physical chemistry. C, Nanomaterials and interfaces. | 25678941 | 2015 Jan 29; |
Use of an organotypic mammalian in vitro follicle growth assay to facilitate female reproductive toxicity screening. | Xu, Yuanming; Duncan, Francesca E; Xu, Min; Woodruff, Teresa K | Reproduction, fertility, and development. | 25689754 | 2015 Feb 18; |
Development of a low-volume, highly sensitive microimmunoassay using computational fluid dynamics-driven multiobjective optimization. | Ghodbane, Mehdi; Kulesa, Anthony; Yu, Henry H; Maguire, Tim J; Schloss, Rene R; Ramachandran, Rohit; Zahn, Jeffrey D; Yarmush, Martin L | Microfluidics and nanofluidics. | 25691853 | 2015 Feb; |
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy. | Ousterout, David G; Kabadi, Ami M; Thakore, Pratiksha I; Majoros, William H; Reddy, Timothy E; Gersbach, Charles A | Nature communications. | 25692716 | 2015 Feb 18; |
Real-time cellular exometabolome analysis with a microfluidic-mass spectrometry platform. | Marasco, Christina C; Enders, Jeffrey R; Seale, Kevin T; McLean, John A; Wikswo, John P | PloS one. | 25723555 | 2015; |
Structural phenotyping of stem cell-derived cardiomyocytes. | Pasqualini, Francesco Silvio; Sheehy, Sean Paul; Agarwal, Ashutosh; Aratyn-Schaus, Yvonne; Parker, Kevin Kit | Stem cell reports. | 25733020 | 2015 Mar 10; |
Vessel network formation in response to intermittent hypoxia is frequency dependent. | Ehsan, Seema M; George, Steven C | Journal of bioscience and bioengineering. | 25735591 | 2015 Sep; |
Initiation of puberty in mice following decellularized ovary transplant. | Laronda, Monica M; Jakus, Adam E; Whelan, Kelly A; Wertheim, Jason A; Shah, Ramille N; Woodruff, Teresa K | Biomaterials. | 25736492 | 2015 May; |
Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling. | Abaci, Hasan Erbil; Shuler, Michael L | Integrative biology : quantitative biosciences from nano to macro. | 25739725 | 2015 Apr; |
Mechanisms of Barrett's oesophagus: intestinal differentiation, stem cells, and tissue models. | Nakagawa, Hiroshi; Whelan, Kelly; Lynch, John P | Best practice & research. Clinical gastroenterology. | 25743452 | 2015 Feb; |
Human iPSC-based cardiac microphysiological system for drug screening applications. | Mathur, Anurag; Loskill, Peter; Shao, Kaifeng; Huebsch, Nathaniel; Hong, SoonGweon; Marcus, Sivan G; Marks, Natalie; Mandegar, Mohammad; Conklin, Bruce R; Lee, Luke P; Healy, Kevin E | Scientific reports. | 25748532 | 2015; |
Phage-display-guided nanocarrier targeting to atheroprone vasculature. | Hofmeister, Lucas H; Lee, Sue Hyun; Norlander, Allison E; Montaniel, Kim Ramil C; Chen, Wei; Harrison, David G; Sung, Hak-Joon | ACS nano. | 25768046 | 2015; |
Engineering mesenchymal stem cells for regenerative medicine and drug delivery. | Park, Ji Sun; Suryaprakash, Smruthi; Lao, Yeh-Hsing; Leong, Kam W | Methods (San Diego, Calif.). | 25770356 | 2015 Aug; |
Engineering the ovarian cycle using in vitro follicle culture. | Skory, Robin M; Xu, Yuanming; Shea, Lonnie D; Woodruff, Teresa K | Human reproduction (Oxford, England). | 25784584 | 2015 Jun; |
Integration of drug, protein, and gene delivery systems with regenerative medicine. | Lorden, Elizabeth R; Levinson, Howard M; Leong, Kam W | Drug delivery and translational research. | 25787742 | 2015 Apr; |
Generating human intestinal tissues from pluripotent stem cells to study development and disease. | Sinagoga, Katie L; Wells, James M | The EMBO journal. | 25792515 | 2015 May 5; |
Profiling and Imaging Ion Mobility-Mass Spectrometry Analysis of Cholesterol and 7-Dehydrocholesterol in Cells Via Sputtered Silver MALDI. | Xu, Libin; Kliman, Michal; Forsythe, Jay G; Korade, Zeljka; Hmelo, Anthony B; Porter, Ned A; McLean, John A | Journal of the American Society for Mass Spectrometry. | 25822928 | 2015 Jun; |
A cost-effective RNA sequencing protocol for large-scale gene expression studies. | Hou, Zhonggang; Jiang, Peng; Swanson, Scott A; Elwell, Angela L; Nguyen, Bao Kim S; Bolin, Jennifer M; Stewart, Ron; Thomson, James A | Scientific reports. | 25831155 | 2015; |
Culturing adult stem cells from mouse small intestinal crypts. | Hamilton, Kathryn E; Crissey, Mary Ann S; Lynch, John P; Rustgi, Anil K | Cold Spring Harbor protocols. | 25834260 | 2015 Apr; |
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow. | Esch, Mandy B; Prot, Jean-Matthieu; Wang, Ying I; Miller, Paula; Llamas-Vidales, Jose Ricardo; Naughton, Brian A; Applegate, Dawn R; Shuler, Michael L | Lab on a chip. | 25857666 | 2015 May 21; |
The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial: an adaptive trial design case study. | Connor, Jason T; Broglio, Kristine R; Durkalski, Valerie; Meurer, William J; Johnston, Karen C | Trials. | 25885963 | 2015; |
NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection. | Juul, Sissel; Obliosca, Judy M; Liu, Cong; Liu, Yen-Liang; Chen, Yu-An; Imphean, Darren M; Knudsen, Birgitta R; Ho, Yi-Ping; Leong, Kam W; Yeh, Hsin-Chih | Nanoscale. | 25901841 | 2015 May 14; |
Differential ?3 Integrin Expression Regulates the Response of Human Lung and Cardiac Fibroblasts to Extracellular Matrix and Its Components. | Merna, Nick; Fung, Kelsey M; Wang, Jean J; King, Cristi R; Hansen, Kirk C; Christman, Karen L; George, Steven C | Tissue engineering. Part A. | 25926101 | 2015 Aug; |
Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor. | Sarkar, Ujjal; Rivera-Burgos, Dinelia; Large, Emma M; Hughes, David J; Ravindra, Kodihalli C; Dyer, Rachel L; Ebrahimkhani, Mohammad R; Wishnok, John S; Griffith, Linda G; Tannenbaum, Steven R | Drug metabolism and disposition: the biological fate of chemicals. | 25926431 | 2015 Jul; |
Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis. | Legocki, Laurie J; Meurer, William J; Frederiksen, Shirley; Lewis, Roger J; Durkalski, Valerie L; Berry, Donald A; Barsan, William G; Fetters, Michael D | BMC medical ethics. | 25933921 | 2015; |
Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues. | Feric, Nicole T; Radisic, Milica | Advanced drug delivery reviews. | 25956564 | 2015 May 5; |
Structural Characterization of Methylenedianiline Regioisomers by Ion Mobility-Mass Spectrometry, Tandem Mass Spectrometry, and Computational Strategies. 2. Electrospray Spectra of 3-Ring and 4-Ring Isomers. | Stow, Sarah M; Onifer, Tiffany M; Forsythe, Jay G; Nefzger, Hartmut; Kwiecien, Nicholas W; May, Jody C; McLean, John A; Hercules, David M | Analytical chemistry. | 25971782 | 2015 Jun 16; |
A phenotypic in vitro model for the main determinants of human whole heart function. | Stancescu, Maria; Molnar, Peter; McAleer, Christopher W; McLamb, William; Long, Christopher J; Oleaga, Carlota; Prot, Jean-Matthieu; Hickman, James J | Biomaterials. | 25978005 | 2015 Aug; |
Fluorescent protein biosensors applied to microphysiological systems. | Senutovitch, Nina; Vernetti, Lawrence; Boltz, Robert; DeBiasio, Richard; Gough, Albert; Taylor, D Lansing | Experimental biology and medicine (Maywood, N.J.). | 25990438 | 2015 Jun; |
Fluorescence lifetime imaging of endogenous biomarker of oxidative stress. | Datta, Rupsa; Alfonso-García, Alba; Cinco, Rachel; Gratton, Enrico | Scientific reports. | 25993434 | 2015; |
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. | Chen, Huanhuan Joyce; Sun, Jian; Huang, Zhiliang; Hou Jr, Harry; Arcilla, Myra; Rakhilin, Nikolai; Joe, Daniel J; Choi, Jiahn; Gadamsetty, Poornima; Milsom, Jeff; Nandakumar, Govind; Longman, Randy; Zhou, Xi Kathy; Edwards, Robert; Chen, Jonlin; Chen, Kai | Nature biotechnology. | 26006007 | 2015 Jun; |
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Tissue-engineered blood vessels as promising tools for testing drug toxicity. | Truskey, George A; Fernandez, Cristina E | Expert opinion on drug metabolism & toxicology. | 26028128 | 2015 Jul; |
3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures. | Hong, Sungmin; Sycks, Dalton; Chan, Hon Fai; Lin, Shaoting; Lopez, Gabriel P; Guilak, Farshid; Leong, Kam W; Zhao, Xuanhe | Advanced materials (Deerfield Beach, Fla.). | 26033288 | 2015 Jul 15; |
The state of the heart: Recent advances in engineering human cardiac tissue from pluripotent stem cells. | Sirabella, Dario; Cimetta, Elisa; Vunjak-Novakovic, Gordana | Experimental biology and medicine (Maywood, N.J.) | 26069271 | 2015 Aug |
Comparative hazard analysis and toxicological modeling of diverse nanomaterials using the embryonic zebrafish (EZ) metric of toxicity. | Harper, Bryan; Thomas, Dennis; Chikkagoudar, Satish; Baker, Nathan; Tang, Kaizhi; Heredia-Langner, Alejandro; Lins, Roberto; Harper, Stacey | Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology. | 26069453 | 2015; |
Blood-brain barrier, bulk flow, and interstitial clearance in epilepsy. | Marchi, Nicola; Banjara, Manoj; Janigro, Damir | Journal of neuroscience methods | 26093166 | 2016 Feb 15 |
Covalent Modification of Synthetic Hydrogels with Bioactive Proteins via Sortase-Mediated Ligation. | Cambria, Elena; Renggli, Kasper; Ahrens, Caroline C; Cook, Christi D; Kroll, Carsten; Krueger, Andrew T; Imperiali, Barbara; Griffith, Linda G | Biomacromolecules | 26098148 | 2015 Aug 10 |
Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors. | Bagley, Alexander F; Scherz-Shouval, Ruth; Galie, Peter A; Zhang, Angela Q; Wyckoff, Jeffrey; Whitesell, Luke; Chen, Christopher S; Lindquist, Susan; Bhatia, Sangeeta N | Cancer research. | 26122846 | 2015 Aug 15; |
Real-Time Monitoring of Cellular Bioenergetics with a Multianalyte Screen-Printed Electrode. | McKenzie, Jennifer R; Cognata, Andrew C; Davis, Anna N; Wikswo, John P; Cliffel, David E | Analytical chemistry. | 26125545 | 2015 Aug 4; |
Development and validation of a microfluidic immunoassay capable of multiplexing parallel samples in microliter volumes. | Ghodbane, Mehdi; Stucky, Elizabeth C; Maguire, Tim J; Schloss, Rene S; Shreiber, David I; Zahn, Jeffrey D; Yarmush, Martin L | Lab on a chip. | 26130452 | 2015 Aug 7; |
Note: A single-chamber tool for plasma activation and surface functionalization in microfabrication. | Bowman, Adam J; Scherrer, Joseph R; Reiserer, Ronald S | The Review of scientific instruments | 26133881 | 2015 Jun |
Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs. | Lee, Eugene K; Kurokawa, Yosuke K; Tu, Robin; George, Steven C; Khine, Michelle | Scientific reports | 26139150 | 2015 Jul 03 |
Biotunable acoustic node assembly of organoids. | Chen, Pu; Güven, Sinan; Usta, Osman Berk; Yarmush, Martin L; Demirci, Utkan | Advanced healthcare materials. | 26149464 | 2015 Sep 16; |
Bioengineering methods for myocardial regeneration. | Parsa, Hesam; Ronaldson, Kacey; Vunjak-Novakovic, Gordana | Advanced drug delivery reviews. | 26150344 | 2015 Jul 4; |
Long-term maintenance of a microfluidic 3D human liver sinusoid. | Prodanov, Ljupcho; Jindal, Rohit; Bale, Shyam Sundhar; Hegde, Manjunath; McCarty, William J; Golberg, Inna; Bhushan, Abhinav; Yarmush, Martin L; Usta, Osman Berk | Biotechnology and bioengineering. | 26152452 | 2016 Jan; |
Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies. | Usta, O B; McCarty, W J; Bale, S; Hegde, M; Jindal, R; Bhushan, A; Golberg, I; Yarmush, M L | Technology. | 26167518 | 2015 Mar; |
Endometriosis and ovarian cancer: links, risks, and challenges faced. | Pavone, Mary Ellen; Lyttle, Brianna M | International journal of women's health. | 26170722 | 2015; |
Self-organizing human cardiac microchambers mediated by geometric confinement. | Ma, Zhen; Wang, Jason; Loskill, Peter; Huebsch, Nathaniel; Koo, Sangmo; Svedlund, Felicia L; Marks, Natalie C; Hua, Ethan W; Grigoropoulos, Costas P; Conklin, Bruce R; Healy, Kevin E | Nature communications | 26172574 | 2015 Jul 14 |
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Microfluidic device to control interstitial flow-mediated homotypic and heterotypic cellular communication. | Alonzo, Luis F; Moya, Monica L; Shirure, Venktesh S; George, Steven C | Lab on a chip. | 26190172 | 2015 Sep 7; |
Broadscale resolving power performance of a high precision uniform field ion mobility-mass spectrometer. | May, Jody C; Dodds, James N; Kurulugama, Ruwan T; Stafford, George C; Fjeldsted, John C; McLean, John A | The Analyst. | 26191544 | 2015 Oct 21; |
MALDI-TOF/TOF CID Study of Poly(1,4-dihydroxybenzene terephthalate) Fragmentation Reactions. | Gies, Anthony P; Stow, Sarah M; McLean, John A; Hercules, David M | Polymer | 26195848 | 2015 May 01 |
A human liver microphysiology platform for investigating physiology, drug safety, and disease models. | Vernetti, Lawrence A; Senutovitch, Nina; Boltz, Robert; DeBiasio, Richard; Ying Shun, Tong; Gough, Albert; Taylor, D Lansing | Experimental biology and medicine (Maywood, N.J.). | 26202373 | 2016 Jan; |
Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes. | Chun, Young Wook; Balikov, Daniel A; Feaster, Tromondae K; Williams, Charles H; Sheng, Calvin C; Lee, Jung-Bok; Boire, Timothy C; Neely, M Diana; Bellan, Leon M; Ess, Kevin C; Bowman, Aaron B; Sung, Hak-Joon; Hong, Charles C | Biomaterials. | 26204225 | 2015 Oct; |
Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening. | Kurokawa, Yosuke K; George, Steven C | Advanced drug delivery reviews | 26212156 | 2016 Jan 15 |
Micropatterning Alginate Substrates for in vitro Cardiovascular Muscle on a Chip. | Agarwal, Ashutosh; Farouz, Yohan; Nesmith, Alexander Peyton; Deravi, Leila F; McCain, Megan Laura; Parker, Kevin Kit | Advanced functional materials. | 26213529 | 2013 Aug 12; |
Use of ChemoFx® for Identification of Effective Treatments in Epithelial Ovarian Cancer. | Richard, Scott; Wells, Alan; Connor, Joseph; Price, Fredric | PLoS currents | 26213638 | 2015 Jul 13 |
A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro. | Adler, Melanie; Ramm, Susanne; Hafner, Marc; Muhlich, Jeremy L; Gottwald, Esther Maria; Weber, Elijah; Jaklic, Alenka; Ajay, Amrendra Kumar; Svoboda, Daniel; Auerbach, Scott; Kelly, Edward J; Himmelfarb, Jonathan; Vaidya, Vishal S | Journal of the American Society of Nephrology : JASN. | 26260164 | 2016 Apr; |
Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments. | Leng, Ning; Chu, Li-Fang; Barry, Chris; Li, Yuan; Choi, Jeea; Li, Xiaomao; Jiang, Peng; Stewart, Ron M; Thomson, James A; Kendziorski, Christina | Nature methods. | 26301841 | 2015 Oct; |
Melanin Transfer in Human 3D Skin Equivalents Generated Exclusively from Induced Pluripotent Stem Cells. | Gledhill, Karl; Guo, Zongyou; Umegaki-Arao, Noriko; Higgins, Claire A; Itoh, Munenari; Christiano, Angela M | PloS one. | 26308443 | 2015; |
The FOXD1 lineage of kidney perivascular cells and myofibroblasts: functions and responses to injury. | Gomez, Ivan G; Duffield, Jeremy S | Kidney international supplements. | 26312147 | 2014 Nov; |
HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy. | Hinson, John T; Chopra, Anant; Nafissi, Navid; Polacheck, William J; Benson, Craig C; Swist, Sandra; Gorham, Joshua; Yang, Luhan; Schafer, Sebastian; Sheng, Calvin C; Haghighi, Alireza; Homsy, Jason; Hubner, Norbert; Church, George; Cook, Stuart A; Linke, Wolfgang A; Chen, Christopher S; Seidman, J G; Seidman, Christine E | Science (New York, N.Y.) | 26315439 | 2015 Aug 28 |
Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems. | Berry, Bonnie J; Akanda, Nesar; Smith, Alec S T; Long, Christopher J; Schnepper, Mark T; Guo, Xiufang; Hickman, James J | Biotechnology progress. | 26317319 | 2015 Nov-Dec; |
In Situ Crosslinkable Gelatin Hydrogels for Vasculogenic Induction and Delivery of Mesenchymal Stem Cells. | Lee, Sue Hyun; Lee, Yunki; Chun, Young Wook; Crowder, Spencer W; Young, Pampee P; Park, Ki Dong; Sung, Hak-Joon | Advanced functional materials. | 26327818 | 2014 Nov 19; |
Projection Stereolithographic Fabrication of Human Adipose Stem Cell-Incorporated Biodegradable Scaffolds for Cartilage Tissue Engineering. | Sun, Aaron X; Lin, Hang; Beck, Angela M; Kilroy, Evan J; Tuan, Rocky S | Frontiers in bioengineering and biotechnology. | 26347860 | 2015; |
Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress. | Kong, Jianping; Whelan, Kelly A; Laczkó, Dorottya; Dang, Brendan; Caro Monroig, Angeliz; Soroush, Ali; Falcone, John; Amaravadi, Ravi K; Rustgi, Anil K; Ginsberg, Gregory G; Falk, Gary W; Nakagawa, Hiroshi; Lynch, John P | Molecular carcinogenesis. | 26373456 | 2015 Sep 16; |
Hydrogel arrays formed via differential wettability patterning enable combinatorial screening of stem cell behavior. | Le, Ngoc Nhi T; Zorn, Stefan; Schmitt, Samantha K; Gopalan, Padma; Murphy, William L | Acta biomaterialia. | 26386315 | 2016 Apr 1; |
Human pluripotent stem cell-derived neural constructs for predicting neural toxicity. | Schwartz, Michael P; Hou, Zhonggang; Propson, Nicholas E; Zhang, Jue; Engstrom, Collin J; Santos Costa, Vitor; Jiang, Peng; Nguyen, Bao Kim; Bolin, Jennifer M; Daly, William; Wang, Yu; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James A | Proceedings of the National Academy of Sciences of the United States of America. | 26392547 | 2015 Oct 6; |
Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin. | Pellett, Sabine; Schwartz, Michael P; Tepp, William H; Josephson, Richard; Scherf, Jacob M; Pier, Christina L; Thomson, James A; Murphy, William L; Johnson, Eric A | Scientific reports. | 26411797 | 2015; |
In vitro cardiac tissue models: Current status and future prospects. | Mathur, Anurag; Ma, Zhen; Loskill, Peter; Jeeawoody, Shaheen; Healy, Kevin E | Advanced drug delivery reviews. | 26428618 | 2016 Jan 15; |
Enabling functional genomics with genome engineering. | Hilton, Isaac B; Gersbach, Charles A | Genome research. | 26430154 | 2015 Oct; |
The Development of TALE Nucleases for Biotechnology. | Ousterout, David G; Gersbach, Charles A | Methods in molecular biology (Clifton, N.J.). | 26443211 | 2016; |
Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors. | Thakore, Pratiksha I; Gersbach, Charles A | Methods in molecular biology (Clifton, N.J.). | 26443215 | 2016; |
Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology. | Saxena, Kapil; Blutt, Sarah E; Ettayebi, Khalil; Zeng, Xi-Lei; Broughman, James R; Crawford, Sue E; Karandikar, Umesh C; Sastri, Narayan P; Conner, Margaret E; Opekun, Antone R; Graham, David Y; Qureshi, Waqar; Sherman, Vadim; Foulke-Abel, Jennifer; In, J | Journal of virology. | 26446608 | 2015 Oct 07; |
RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis. | Craciun, Florin L; Bijol, Vanesa; Ajay, Amrendra K; Rao, Poornima; Kumar, Ramya K; Hutchinson, John; Hofmann, Oliver; Joshi, Nikita; Luyendyk, James P; Kusebauch, Ulrike; Moss, Christopher L; Srivastava, Anand; Himmelfarb, Jonathan; Waikar, Sushrut S; Moritz, Robert L; Vaidya, Vishal S | Journal of the American Society of Nephrology : JASN. | 26449608 | 2016 Jun; |
Systems-Wide High-Dimensional Data Acquisition and Informatics Using Structural Mass Spectrometry Strategies. | Sherrod, Stacy D; McLean, John A | Clinical chemistry. | 26453699 | 2016 Jan; |
Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. | Jung, Youngmee; Ji, HaYeun; Chen, Zaozao; Fai Chan, Hon; Atchison, Leigh; Klitzman, Bruce; Truskey, George; Leong, Kam W | Scientific reports. | 26456074 | 2015; |
Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia. | Kong, Jianping; Sai, Hong; Crissey, Mary Ann S; Jhala, Nirag; Falk, Gary W; Ginsberg, Gregory G; Abrams, Julian A; Nakagawa, Hiroshi; Wang, Kenneth; Rustgi, Anil K; Wang, Timothy C; Lynch, John P | Oncotarget. | 26460825 | 2015 Oct 20; |
Patterned polymer matrix promotes stemness and cell-cell interaction of adult stem cells. | Hofmeister, Lucas H; Costa, Lino; Balikov, Daniel A; Crowder, Spencer W; Terekhov, Alexander; Sung, Hak-Joon; Hofmeister, William H | Journal of biological engineering. | 26464581 | 2015; |
Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain depends on disease status. | Chun, Young Wook; Voyles, David E; Rath, Rutwik; Hofmeister, Lucas H; Boire, Timothy C; Wilcox, Henry; Lee, Jae Han; Bellan, Leon M; Hong, Charles C; Sung, Hak-Joon | Journal of biomechanics. | 26476764 | 2015 Nov 5; |
Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization. | McCarty, William J; Prodanov, Ljupcho; Bale, Shyam Sundhar; Bhushan, Abhinav; Jindal, Rohit; Yarmush, Martin L; Usta, O Berk | Journal of visualized experiments : JoVE. | 26485274 | 2015; |
Physiome-on-a-Chip: The Challenge of "Scaling" in Design, Operation, and Translation of Microphysiological Systems. | Stokes, C L; Cirit, M; Lauffenburger, D A | CPT: pharmacometrics & systems pharmacology | 26535154 | 2015 Oct |
Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration. | Yu, J; Cilfone, N A; Large, E M; Sarkar, U; Wishnok, J S; Tannenbaum, S R; Hughes, D J; Lauffenburger, D A; Griffith, L G; Stokes, C L; Cirit, M | CPT: pharmacometrics & systems pharmacology | 26535159 | 2015 Oct |
Tough bonding of hydrogels to diverse non-porous surfaces. | Yuk, Hyunwoo; Zhang, Teng; Lin, Shaoting; Parada, German Alberto; Zhao, Xuanhe | Nature materials. | 26552058 | 2016 Feb; |
Is phosphorylated tau unique to chronic traumatic encephalopathy? Phosphorylated tau in epileptic brain and chronic traumatic encephalopathy. | Puvenna, Vikram; Engeler, Madeline; Banjara, Manoj; Brennan, Chanda; Schreiber, Peter; Dadas, Aaron; Bahrami, Ashkon; Solanki, Jesal; Bandyopadhyay, Anasua; Morris, Jacqueline K; Bernick, Charles; Ghosh, Chaitali; Rapp, Edward; Bazarian, Jeffrey J; Janigr | Brain research. | 26556772 | 2016 Jan 1; |
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor. | Brown, Jacquelyn A; Pensabene, Virginia; Markov, Dmitry A; Allwardt, Vanessa; Neely, M Diana; Shi, Mingjian; Britt, Clayton M; Hoilett, Orlando S; Yang, Qing; Brewer, Bryson M; Samson, Philip C; McCawley, Lisa J; May, James M; Webb, Donna J; Li, Deyu; Bow | Biomicrofluidics. | 26576206 | 2015 Sep; |
Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1?/nerve growth factor signaling. | Jiang, Yangzi; Hu, Changchang; Yu, Shuting; Yan, Junwei; Peng, Hsuan; Ouyang, Hong Wei; Tuan, Rocky S | Arthritis research & therapy. | 26577823 | 2015; |
Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model. | Rivera-Burgos, Dinelia; Sarkar, Ujjal; Lever, Amanda R; Avram, Michael J; Coppeta, Jonathan R; Wishnok, John S; Borenstein, Jeffrey T; Tannenbaum, Steven R | Drug metabolism and disposition: the biological fate of chemicals. | 26586376 | 2016 Feb; |
Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels. | Wang, Xiaolin; Phan, Duc T T; Sobrino, Agua; George, Steven C; Hughes, Christopher C W; Lee, Abraham P | Lab on a chip | 26616908 | 2016 Jan 21 |
Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study. | Guetterman, Timothy C; Fetters, Michael D; Legocki, Laurie J; Mawocha, Samkeliso; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J | Clinical research and regulatory affairs. | 26622163 | 2015 Oct 2; |
Novel behavior of the chromatographic separation of linear and cyclic polymers. | Montenegro-Burke, J Rafael; Bennett, Jackson M; McLean, John A; Hercules, David M | Analytical and bioanalytical chemistry. | 26637218 | 2016 Jan; |
Stretchable Hydrogel Electronics and Devices. | Lin, Shaoting; Yuk, Hyunwoo; Zhang, Teng; Parada, German Alberto; Koo, Hyunwoo; Yu, Cunjiang; Zhao, Xuanhe | Advanced materials (Deerfield Beach, Fla.). | 26639322 | 2015 Dec 7; |
Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease. | Bursac, Nenad; Juhas, Mark; Rando, Thomas A | Annual review of biomedical engineering | 26643021 | 2015 |
A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis. | Smirnova, L; Harris, G; Delp, J; Valadares, M; Pamies, D; Hogberg, H T; Waldmann, T; Leist, M; Hartung, T | Archives of toxicology. | 26647301 | 2016 Nov; |
Fibrous scaffolds for building hearts and heart parts. | Capulli, A K; MacQueen, L A; Sheehy, Sean P; Parker, K K | Advanced drug delivery reviews. | 26656602 | 2016 Jan 15; |
A Novel Three-Dimensional Human Peritubular Microvascular System. | Ligresti, Giovanni; Nagao, Ryan J; Xue, Jun; Choi, Yoon Jung; Xu, Jin; Ren, Shuyu; Aburatani, Takahide; Anderson, Susan K; MacDonald, James W; Bammler, Theo K; Schwartz, Stephen M; Muczynski, Kimberly A; Duffield, Jeremy S; Himmelfarb, Jonathan; Zheng, Yi | Journal of the American Society of Nephrology : JASN. | 26657868 | 2016 Aug; |
Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology. | Zachos, Nicholas C; Kovbasnjuk, Olga; Foulke-Abel, Jennifer; In, Julie; Blutt, Sarah E; de Jonge, Hugo R; Estes, Mary K; Donowitz, Mark | The Journal of biological chemistry. | 26677228 | 2016 Feb 19; |
Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. | Foulke-Abel, Jennifer; In, Julie; Yin, Jianyi; Zachos, Nicholas C; Kovbasnjuk, Olga; Estes, Mary K; de Jonge, Hugo; Donowitz, Mark | Gastroenterology. | 26677983 | 2016 Mar; |
Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification. | Logan, David J; Shan, Jing; Bhatia, Sangeeta N; Carpenter, Anne E | Methods (San Diego, Calif.). | 26687239 | 2016 Mar 1; |
Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. | Heylman, Christopher; Datta, Rupsa; Sobrino, Agua; George, Steven; Gratton, Enrico | PloS one | 26695765 | 2015 |
Liver-Regenerative Transplantation: Regrow and Reset. | Collin de l'Hortet, A; Takeishi, K; Guzman-Lepe, J; Handa, K; Matsubara, K; Fukumitsu, K; Dorko, K; Presnell, S C; Yagi, H; Soto-Gutierrez, A | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons | 26699680 | 2016 Jun |
Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism. | Yamaura, Yoshiyuki; Chapron, Brian D; Wang, Zhican; Himmelfarb, Jonathan; Thummel, Kenneth E | Drug metabolism and disposition: the biological fate of chemicals. | 26700954 | 2016 Mar; |
Tissue Engineering and Regenerative Medicine 2015: A Year in Review. | Wobma, Holly; Vunjak-Novakovic, Gordana | Tissue engineering. Part B, Reviews. | 26714410 | 2016 Apr; |
Tissue-Engineering for the Study of Cardiac Biomechanics. | Ma, Stephen P; Vunjak-Novakovic, Gordana | Journal of biomechanical engineering. | 26720588 | 2016 Feb; |
OEFinder: a user interface to identify and visualize ordering effects in single-cell RNA-seq data. | Leng, Ning; Choi, Jeea; Chu, Li-Fang; Thomson, James A; Kendziorski, Christina; Stewart, Ron | Bioinformatics (Oxford, England). | 26743507 | 2016 May 01; |
Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. | Eng, George; Lee, Benjamin W; Protas, Lev; Gagliardi, Mark; Brown, Kristy; Kass, Robert S; Keller, Gordon; Robinson, Richard B; Vunjak-Novakovic, Gordana | Nature communications | 26785135 | 2016 Jan 19 |
High-density lipoprotein subclass measurements improve mortality risk prediction, discrimination and reclassification in a cardiac catheterization cohort. | McGarrah, Robert W; Craig, Damian M; Haynes, Carol; Dowdy, Z Elaine; Shah, Svati H; Kraus, William E | Atherosclerosis. | 26803432 | 2016 Mar; |
Angiotensin II Induced Cardiac Dysfunction on a Chip. | Horton, Renita E; Yadid, Moran; McCain, Megan L; Sheehy, Sean P; Pasqualini, Francesco S; Park, Sung-Jin; Cho, Alexander; Campbell, Patrick; Parker, Kevin Kit | PloS one | 26808388 | 2016 |
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs. | Oleaga, Carlota; Bernabini, Catia; Smith, Alec S T; Srinivasan, Balaji; Jackson, Max; McLamb, William; Platt, Vivien; Bridges, Richard; Cai, Yunqing; Santhanam, Navaneetha; Berry, Bonnie; Najjar, Sarah; Akanda, Nesar; Guo, Xiufang; Martin, Candace; Ekman, | Scientific reports. | 26837601 | 2016; |
Enterohemorrhagic Escherichia coli reduce mucus and intermicrovillar bridges in human stem cell-derived colonoids. | In, Julie; Foulke-Abel, Jennifer; Zachos, Nicholas C; Hansen, Anne-Marie; Kaper, James B; Bernstein, Harris D; Halushka, Marc; Blutt, Sarah; Estes, Mary K; Donowitz, Mark; Kovbasnjuk, Olga | Cellular and molecular gastroenterology and hepatology. | 26855967 | 2016 Jan 1; |
Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy. | Aratyn-Schaus, Yvonne; Pasqualini, Francesco S; Yuan, Hongyan; McCain, Megan L; Ye, George J C; Sheehy, Sean P; Campbell, Patrick H; Parker, Kevin Kit | The Journal of cell biology. | 26858266 | 2016 Feb 15; |
Modular Assembly Approach to Engineer Geometrically Precise Cardiovascular Tissue. | Lee, Benjamin W; Liu, Bohao; Pluchinsky, Adam; Kim, Nathan; Eng, George; Vunjak-Novakovic, Gordana | Advanced healthcare materials. | 26865105 | 2016 Apr; |
Transdifferentiation of human endothelial progenitors into smooth muscle cells. | Ji, HaYeun; Atchison, Leigh; Chen, Zaozao; Chakraborty, Syandan; Jung, Youngmee; Truskey, George A; Christoforou, Nicolas; Leong, Kam W | Biomaterials. | 26874281 | 2016 Apr; |
Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators. | Moyle-Heyrman, Georgette; Schipma, Matthew J; Dean, Matthew; Davis, David A; Burdette, Joanna E | Journal of ovarian research. | 26879975 | 2016 Feb 15; |
Human Vascular Microphysiological System for in vitro Drug Screening. | Fernandez, C E; Yen, R W; Perez, S M; Bedell, H W; Povsic, T J; Reichert, W M; Truskey, G A | Scientific reports | 26888719 | 2016 Feb 18 |
SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. | Tobita, Takamasa; Guzman-Lepe, Jorge; Takeishi, Kazuki; Nakao, Toshimasa; Wang, Yang; Meng, Fanying; Deng, Chu-Xia; Collin de l'Hortet, Alexandra; Soto-Gutierrez, Alejandro | PloS one | 26890260 | 2016 |
Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. | Cheng, Cindy S; Ran, Lydia; Bursac, Nenad; Kraus, William E; Truskey, George A | Tissue engineering. Part A. | 26891613 | 2016 Apr; |
A novel low-volume two-chamber microfabricated platform for evaluating drug metabolism and toxicity. | Bale, Shyam Sundhar; Sridharan, Gautham Vivek; Golberg, Inna; Prodanov, Ljupcho; McCarty, William J; Usta, Osman Berk; Jindal, Rohit; Yarmush, Martin L | Technology. | 26925437 | 2015 Dec; |
Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels. | Zanotelli, Matthew R; Ardalani, Hamisha; Zhang, Jue; Hou, Zhonggang; Nguyen, Eric H; Swanson, Scott; Nguyen, Bao Kim; Bolin, Jennifer; Elwell, Angela; Bischel, Lauren L; Xie, Angela W; Stewart, Ron; Beebe, David J; Thomson, James A; Schwartz, Michael P; Murphy, William L | Acta biomaterialia. | 26945632 | 2016 Apr 15; |
A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine. | Stern, Andrew M; Schurdak, Mark E; Bahar, Ivet; Berg, Jeremy M; Taylor, D Lansing | Journal of biomolecular screening. | 26962875 | 2016 Jul; |
TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease. | Gomez, Ivan G; Roach, Allie M; Nakagawa, Naoki; Amatucci, Aldo; Johnson, Bryce G; Dunn, Kadeshia; Kelly, Mark C; Karaca, Gamze; Zheng, Timothy S; Szak, Suzanne; Peppiatt-Wildman, Claire M; Burkly, Linda C; Duffield, Jeremy S | Journal of the American Society of Nephrology : JASN. | 27026366 | ; |
Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions. | Chan, Hon Fai; Zhang, Ying; Leong, Kam W | Small (Weinheim an der Bergstrasse, Germany). | 27038291 | 2016 May; |
Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies? | Chan, Hon Fai; Ma, Siying; Leong, Kam W | Regenerative biomaterials. | 27047674 | 2016 Jun; |
Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. | Huebsch, Nathaniel; Loskill, Peter; Deveshwar, Nikhil; Spencer, C Ian; Judge, Luke M; Mandegar, Mohammad A; Fox, Cade B; Mohamed, Tamer M A; Ma, Zhen; Mathur, Anurag; Sheehan, Alice M; Truong, Annie; Saxton, Mike; Yoo, Jennie; Srivastava, Deepak; Desai, Tejal A; So, Po-Lin; Healy, Kevin E; Conklin, Bruce R | Scientific reports. | 27095412 | 2016; |
Bioengineered Models of Solid Human Tumors for Cancer Research. | Marturano-Kruik, Alessandro; Villasante, Aranzazu; Vunjak-Novakovic, Gordana | Methods in molecular biology (Clifton, N.J.). | 27115504 | 2016 Apr 27; |
Human Cartilage-Derived Progenitor Cells From Committed Chondrocytes for Efficient Cartilage Repair and Regeneration. | Jiang, Yangzi; Cai, Youzhi; Zhang, Wei; Yin, Zi; Hu, Changchang; Tong, Tong; Lu, Ping; Zhang, Shufang; Neculai, Dante; Tuan, Rocky S; Ouyang, Hong Wei | Stem cells translational medicine. | 27130221 | 2016 Jun; |
Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response. | Bale, Shyam Sundhar; Geerts, Sharon; Jindal, Rohit; Yarmush, Martin L | Scientific reports. | 27142224 | 2016 May 04; |
Modeling tumor microenvironments using custom-designed biomaterial scaffolds. | Liu, Zen; Vunjak-Novakovic, Gordana | Current opinion in chemical engineering. | 27152253 | 2016 Feb; |
Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro. | Capulli, Andrew K; MacQueen, Luke A; O'Connor, Blakely B; Dauth, Stephanie; Parker, Kevin Kit | Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. | 27174867 | 2016 Jul-Aug; |
Forces and mechanotransduction in 3D vascular biology. | Kutys, Matthew L; Chen, Christopher S | Current opinion in cell biology. | 27209346 | 2016 May 19; |
Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes. | Datta, Rupsa; Heylman, Christopher; George, Steven C; Gratton, Enrico | Biomedical optics express | 27231614 | 2016 May 01 |
A Microfabricated Platform for Generating Physiologically-Relevant Hepatocyte Zonation. | McCarty, William J; Usta, O Berk; Yarmush, Martin L | Scientific reports. | 27240736 | 2016 May 31; |
Striated muscle function, regeneration, and repair. | Shadrin, I Y; Khodabukus, A; Bursac, N | Cellular and molecular life sciences : CMLS. | 27271751 | 2016 Jun 6; |
Recapitulating the Size and Cargo of Tumor Exosomes in a Tissue-Engineered Model. | Villasante, Aranzazu; Marturano-Kruik, Alessandro; Ambati, Srikanth R; Liu, Zen; Godier-Furnemont, Amandine; Parsa, Hesam; Lee, Benjamin W; Moore, Malcolm A S; Vunjak-Novakovic, Gordana | Theranostics. | 27279906 | 2016; |
Distilling complexity to advance cardiac tissue engineering. | Ogle, Brenda M; Bursac, Nenad; Domian, Ibrahim; Huang, Ngan F; Menasché, Philippe; Murry, Charles E; Pruitt, Beth; Radisic, Milica; Wu, Joseph C; Wu, Sean M; Zhang, Jianyi; Zimmermann, Wolfram-Hubertus; Vunjak-Novakovic, Gordana | Science translational medicine | 27280684 | 2016 Jun 08 |
Automated detection and analysis of depolarization events in human cardiomyocytes using MaDEC. | Szymanska, Agnieszka F; Heylman, Christopher; Datta, Rupsa; Gratton, Enrico; Nenadic, Zoran | Computers in biology and medicine. | 27281718 | 2016 Aug 1; |
Engineering a perfusable 3D human liver platform from iPS cells. | Schepers, Arnout; Li, Cheri; Chhabra, Arnav; Seney, Benjamin Tschudy; Bhatia, Sangeeta | Lab on a chip. | 27296616 | 2016 Jul 5; |
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Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge. | May, Jody C; McLean, John A | Annual review of analytical chemistry (Palo Alto, Calif.). | 27306312 | 2016 Jun 12; |
Pathophysiological implications of neurovascular P450 in brain disorders. | Ghosh, Chaitali; Hossain, Mohammed; Solanki, Jesal; Dadas, Aaron; Marchi, Nicola; Janigro, Damir | Drug discovery today. | 27312874 | 2016 Jun 14; |
Evaluation of Collision Cross Section Calibrants for Structural Analysis of Lipids by Traveling Wave Ion Mobility-Mass Spectrometry. | Hines, Kelly M; May, Jody C; McLean, John A; Xu, Libin | Analytical chemistry. | 27321977 | 2016 Jul 19; |
Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC-Derived Endothelial Cells. | Abaci, Hasan E; Guo, Zongyou; Coffman, Abigail; Gillette, Brian; Lee, Wen-Han; Sia, Samuel K; Christiano, Angela M | Advanced healthcare materials. | 27333469 | 2016 Jul; |
Isolation of Murine Embryonic Hemogenic Endothelial Cells. | Fang, Jennifer S; Gritz, Emily C; Marcelo, Kathrina L; Hirschi, Karen K | Journal of visualized experiments : JoVE. | 27341393 | 2016 06 17; |
Skin-inspired hydrogel-elastomer hybrids with robust interfaces and functional microstructures. | Yuk, Hyunwoo; Zhang, Teng; Parada, German Alberto; Liu, Xinyue; Zhao, Xuanhe | Nature communications. | 27345380 | 2016 Jun 27; |
Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells. | Yang, Min; Ma, Bo; Shao, Hanshuang; Clark, Amanda M; Wells, Alan | BMC cancer. | 27387344 | 2016 Jul 07; |
Phototactic guidance of a tissue-engineered soft-robotic ray. | Park, Sung-Jin; Gazzola, Mattia; Park, Kyung Soo; Park, Shirley; Di Santo, Valentina; Blevins, Erin L; Lind, Johan U; Campbell, Patrick H; Dauth, Stephanie; Capulli, Andrew K; Pasqualini, Francesco S; Ahn, Seungkuk; Cho, Alexander; Yuan, Hongyan; Maoz, Be | Science (New York, N.Y.). | 27387948 | 2016 Jul 8; |
Liver metastases: Microenvironments and ex-vivo models. | Clark, Amanda M; Ma, Bo; Taylor, D Lansing; Griffith, Linda; Wells, Alan | Experimental biology and medicine (Maywood, N.J.). | 27390264 | 2016 Sep; |
A recellularized human colon model identifies cancer driver genes. | Chen, Huanhuan Joyce; Wei, Zhubo; Sun, Jian; Bhattacharya, Asmita; Savage, David J; Serda, Rita; Mackeyev, Yuri; Curley, Steven A; Bu, Pengcheng; Wang, Lihua; Chen, Shuibing; Cohen-Gould, Leona; Huang, Emina; Shen, Xiling; Lipkin, Steven M; Copeland, Neal | Nature biotechnology. | 27398792 | 2016 Aug; |
Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening. | Wang, Ying I; Abaci, Hasan Erbil; Shuler, Michael L | Biotechnology and bioengineering. | 27399645 | 2017 01; |
Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function. | Chang, Shih-Yu; Weber, Elijah J; Van Ness, Kirk P; Eaton, David L; Kelly, Edward J | Clinical pharmacology and therapeutics. | 27448090 | 2016 Jul 22; |
Stress-Induced Premature Senescence of Endothelial and Endothelial Progenitor Cells. | Goligorsky, M S; Hirschi, K | Advances in pharmacology (San Diego, Calif.). | 27451101 | 2016; |
Attitudes and opinions regarding confirmatory adaptive clinical trials: a mixed methods analysis from the Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT) project. | Meurer, William J; Legocki, Laurie; Mawocha, Samkeliso; Frederiksen, Shirley M; Guetterman, Timothy C; Barsan, William; Lewis, Roger; Berry, Donald; Fetters, Michael | Trials. | 27473126 | 2016 Jul 29; |
Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins. | Pattison, Amanda M; Blomain, Erik S; Merlino, Dante J; Wang, Fang; Crissey, Mary Ann S; Kraft, Crystal L; Rappaport, Jeff A; Snook, Adam E; Lynch, John P; Waldman, Scott A | Infection and immunity. | 27481254 | 2016 Oct; |
Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence. | Nagao, Ryan J; Xu, Jin; Luo, Ping; Xue, Jun; Wang, Yi; Kotha, Surya; Zeng, Wen; Fu, Xiaoyun; Himmelfarb, Jonathan; Zheng, Ying | Tissue engineering. Part A. | 27481445 | 2016 Aug 30; |
Liver Protects Metastatic Prostate Cancer From Induced Death by Activating E-cadherin Signaling. | Ma, Bo; Wheeler, Sarah E; Clark, Amanda M; Whaley, Diana L; Yang, Min; Wells, Alan | Hepatology (Baltimore, Md.). | 27482645 | 2016 Aug 2; |
Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures. | Lizama-Manibusan, Britney N; Klein, Sharon; McKenzie, Jennifer R; Cliffel, David E; McLaughlin, BethAnn | ACS chemical neuroscience. | 27504748 | 2016 Sep 21; |
Ultrathin Polymer Membranes with Patterned, Micrometric Pores for Organs-on-Chips. | Pensabene, Virginia; Costa, Lino; Terekhov, Alexander Y; Gnecco, Juan S; Wikswo, John P; Hofmeister, William H | ACS applied materials & interfaces. | 27513606 | 2016 Aug 31; |
Development of a microphysiological model of human kidney proximal tubule function. | Weber, Elijah J; Chapron, Alenka; Chapron, Brian D; Voellinger, Jenna L; Lidberg, Kevin A; Yeung, Catherine K; Wang, Zhican; Yamaura, Yoshiyuki; Hailey, Dale W; Neumann, Thomas; Shen, Danny D; Thummel, Kenneth E; Muczynski, Kimberly A; Himmelfarb, Jonathan; Kelly, Edward J | Kidney international. | 27521113 | 2016 Sep; |
Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm. | Chu, Li-Fang; Leng, Ning; Zhang, Jue; Hou, Zhonggang; Mamott, Daniel; Vereide, David T; Choi, Jeea; Kendziorski, Christina; Stewart, Ron; Thomson, James A | Genome biology. | 27534536 | 2016 Aug 17; |
Human fallopian tube epithelium co-culture with murine ovarian follicles reveals crosstalk in the reproductive cycle. | Zhu, Jie; Xu, Yuanming; Rashedi, Alexandra S; Pavone, Mary Ellen; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna E | Molecular human reproduction. | 27542947 | 2016 Nov; |
3D microtumors in vitro supported by perfused vascular networks. | Sobrino, Agua; Phan, Duc T T; Datta, Rupsa; Wang, Xiaolin; Hachey, Stephanie J; Romero-López, Mónica; Gratton, Enrico; Lee, Abraham P; George, Steven C; Hughes, Christopher C W | Scientific reports. | 27549930 | 2016 Aug 23; |
Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface. | Karthikeyan, Subbulakshmi; Lantvit, Daniel D; Chae, Dam Hee; Burdette, Joanna E | Oncotarget. | 27563818 | 2016 10 25; |
Biomimetic on-a-chip platforms for studying cancer metastasis. | Lee, Esak; Song, H-H Greco; Chen, Christopher S | Current opinion in chemical engineering. | 27570735 | 2016 Feb; |
Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies. | Hofer, Heidi R; Tuan, Rocky S | Stem cell research & therapy. | 27612948 | 2016 Sep 09; |
Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform. | Long, Thomas J; Cosgrove, Patrick A; Dunn 2nd, Robert T; Stolz, Donna B; Hamadeh, Hisham; Afshari, Cynthia; McBride, Helen; Griffith, Linda G | Drug metabolism and disposition: the biological fate of chemicals. | 27621203 | 2016 Dec; |
Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics. | Prasad, Bhagwat; Johnson, Katherine; Billington, Sarah; Lee, Caroline; Chung, Git W; Brown, Colin D A; Kelly, Edward J; Himmelfarb, Jonathan; Unadkat, Jashvant D | Drug metabolism and disposition: the biological fate of chemicals. | 27621205 | 2016 Dec; |
Untargeted Metabolomics Strategies-Challenges and Emerging Directions. | Schrimpe-Rutledge, Alexandra C; Codreanu, Simona G; Sherrod, Stacy D; McLean, John A | Journal of the American Society for Mass Spectrometry. | 27624161 | 2016 Dec; |
Determination of ion mobility collision cross sections for unresolved isomeric mixtures using tandem mass spectrometry and chemometric deconvolution. | Harper, Brett; Neumann, Elizabeth K; Stow, Sarah M; May, Jody C; McLean, John A; Solouki, Touradj | Analytica chimica acta. | 27639144 | 2016 Oct 05; |
High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro. | Shan, Jing; Logan, David J; Root, David E; Carpenter, Anne E; Bhatia, Sangeeta N | Journal of biomolecular screening. | 27650791 | 2016 Oct; |
S100B and S100B autoantibody as biomarkers for early detection of brain metastases in lung cancer. | Choi, Humberto; Puvenna, Vikram; Brennan, Chanda; Mahmoud, Shamseldeen; Wang, Xiao-Feng; Phillips, Michael; Janigro, Damir; Mazzone, Peter | Translational lung cancer research. | 27652205 | 2016 Aug; |
Distributed and Lumped Parameter Models for the Characterization of High Throughput Bioreactors. | Iannetti, Laura; D'Urso, Giovanna; Conoscenti, Gioacchino; Cutrì, Elena; Tuan, Rocky S; Raimondi, Manuela T; Gottardi, Riccardo; Zunino, Paolo | PloS one. | 27669413 | 2016; |
Human mini-guts: new insights into intestinal physiology and host-pathogen interactions. | In, Julie G; Foulke-Abel, Jennifer; Estes, Mary K; Zachos, Nicholas C; Kovbasnjuk, Olga; Donowitz, Mark | Nature reviews. Gastroenterology & hepatology. | 27677718 | 2016 Nov; |
Tissue engineering of the heart: An evolving paradigm. | Vunjak-Novakovic, Gordana | The Journal of thoracic and cardiovascular surgery. | 27692954 | 2017 03; |
Organ Chips: Quality Assurance Systems in Regenerative Medicine. | Pasqualini, Francesco S; Emmert, Maximillian Y; Parker, Kevin Kit; Hoerstrup, Simon P | Clinical pharmacology and therapeutics. | 27709615 | 2016 Oct 6; |
Dynamic culture yields engineered myocardium with near-adult functional output. | Jackman, Christopher P; Carlson, Aaron L; Bursac, Nenad | Biomaterials. | 27723557 | 2016 Dec; |
Fringe instability in constrained soft elastic layers. | Lin, Shaoting; Cohen, Tal; Zhang, Teng; Yuk, Hyunwoo; Abeyaratne, Rohan; Zhao, Xuanhe | Soft matter. | 27731462 | 2016 Oct 12; |
Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System. | Tsamandouras, N; Kostrzewski, T; Stokes, C L; Griffith, L G; Hughes, D J; Cirit, M | The Journal of pharmacology and experimental therapeutics. | 27760784 | 2017 Jan; |
Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing. | Lind, Johan U; Busbee, Travis A; Valentine, Alexander D; Pasqualini, Francesco S; Yuan, Hongyan; Yadid, Moran; Park, Sung-Jin; Kotikian, Arda; Nesmith, Alexander P; Campbell, Patrick H; Vlassak, Joost J; Lewis, Jennifer A; Parker, Kevin K | Nature materials. | 27775708 | 2016 Oct 24; |
A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. | Korthauer, Keegan D; Chu, Li-Fang; Newton, Michael A; Li, Yuan; Thomson, James; Stewart, Ron; Kendziorski, Christina | Genome biology. | 27782827 | 2016 Oct 25; |
Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation. | Cil, Onur; Phuan, Puay-Wah; Son, Jung-Ho; Zhu, Jie S; Ku, Colton K; Tabib, Niloufar Akhavan; Teuthorn, Andrew P; Ferrera, Loretta; Zachos, Nicholas C; Lin, Ruxian; Galietta, Luis J V; Donowitz, Mark; Kurth, Mark J; Verkman, Alan S | Translational research : the journal of laboratory and clinical medicine. | 27815136 | 2017 Apr; |
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1? Production. | Ceneri, Nicolle; Zhao, Lina; Young, Bryan D; Healy, Abigail; Coskun, Suleyman; Vasavada, Hema; Yarovinsky, Timur O; Ike, Kenneth; Pardi, Ruggero; Qin, Lingfen; Qin, Li; Tellides, George; Hirschi, Karen; Meadows, Judith; Soufer, Robert; Chun, Hyung J; Sade | Arteriosclerosis, thrombosis, and vascular biology. | 27834690 | 2017 Feb; |
Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy. | Vernetti, Lawrence A; Vogt, Andreas; Gough, Albert; Taylor, D Lansing | Clinics in liver disease. | 27842772 | 2017 02; |
Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury. | Leaf, Irina A; Nakagawa, Shunsaku; Johnson, Bryce G; Cha, Jin Joo; Mittelsteadt, Kristen; Guckian, Kevin M; Gomez, Ivan G; Altemeier, William A; Duffield, Jeremy S | The Journal of clinical investigation. | 27869651 | 2017 Jan 03; |
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. | Workman, Michael J; Mahe, Maxime M; Trisno, Stephen; Poling, Holly M; Watson, Carey L; Sundaram, Nambirajan; Chang, Ching-Fang; Schiesser, Jacqueline; Aubert, Philippe; Stanley, Edouard G; Elefanty, Andrew G; Miyaoka, Yuichiro; Mandegar, Mohammad A; Conkl | Nature medicine. | 27869805 | 2017 Jan; |
Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for anti-secretory therapy of diarrheas caused by bacterial enterotoxins. | Cil, Onur; Phuan, Puay-Wah; Gillespie, Anne Marie; Lee, Sujin; Tradtrantip, Lukmanee; Yin, Jianyi; Tse, Ming; Zachos, Nicholas C; Lin, Ruxian; Donowitz, Mark; Verkman, Alan S | FASEB journal : official publication of the Federation of American Societies for Experimental Biology. | 27871064 | 2016 Nov 08; |
Lipid profiling of polarized human monocyte-derived macrophages. | Montenegro-Burke, J Rafael; Sutton, Jessica A; Rogers, Lisa M; Milne, Ginger L; McLean, John A; Aronoff, David M | Prostaglandins & other lipid mediators. | 27871801 | 2016 12; |
A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity. | Pamies, David; Barreras, Paula; Block, Katharina; Makri, Georgia; Kumar, Anupama; Wiersma, Daphne; Smirnova, Lenna; Zang, Ce; Bressler, Joseph; Christian, Kimberly M; Harris, Georgina; Ming, Guo-Li; Berlinicke, Cindy J; Kyro, Kelly; Song, Hongjun; Pardo, Carlos A; Hartung, Thomas; Hogberg, Helena T | ALTEX. | 27883356 | 2017; |
Good manufacturing practice requirements for the production of tissue vitrification and warming and recovery kits for clinical research. | Laronda, Monica M; McKinnon, Kelly E; Ting, Alison Y; Le Fever, Ann V; Zelinski, Mary B; Woodruff, Teresa K | Journal of assisted reproduction and genetics. | 27900615 | ; |
A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control. | Coppeta, J R; Mescher, M J; Isenberg, B C; Spencer, A J; Kim, E S; Lever, A R; Mulhern, T J; Prantil-Baun, R; Comolli, J C; Borenstein, J T | Lab on a chip. | 27901159 | ; |
Improving the clinical management of traumatic brain injury through the pharmacokinetic modeling of peripheral blood biomarkers. | Dadas, Aaron; Washington, Jolewis; Marchi, Nicola; Janigro, Damir | Fluids and barriers of the CNS. | 27903281 | 2016 Nov 30; |
3D culture models of tissues under tension. | Eyckmans, Jeroen; Chen, Christopher S | Journal of cell science. | 27909243 | 2017 Jan 01; |
A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties. | Clark, A M; Wheeler, S E; Young, C L; Stockdale, L; Shepard Neiman, J; Zhao, W; Stolz, D B; Venkataramanan, R; Lauffenburger, D; Griffith, L; Wells, A | Lab on a chip. | 27910972 | 2016 Dec 20; |
Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease. | Nakagawa, Naoki; Barron, Luke; Gomez, Ivan G; Johnson, Bryce G; Roach, Allie M; Kameoka, Sei; Jack, Richard M; Lupher Jr, Mark L; Gharib, Sina A; Duffield, Jeremy S | JCI insight. | 27942582 | 2016 Dec 08; |
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit. | Brown, Jacquelyn A; Codreanu, Simona G; Shi, Mingjian; Sherrod, Stacy D; Markov, Dmitry A; Neely, M Diana; Britt, Clayton M; Hoilett, Orlando S; Reiserer, Ronald S; Samson, Philip C; McCawley, Lisa J; Webb, Donna J; Bowman, Aaron B; McLean, John A; Wikswo | Journal of neuroinflammation. | 27955696 | 2016 Dec 12; |
Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. | Hinson, J Travis; Chopra, Anant; Lowe, Andre; Sheng, Calvin C; Gupta, Rajat M; Kuppusamy, Rajarajan; O'Sullivan, John; Rowe, Glenn; Wakimoto, Hiroko; Gorham, Joshua; Zhang, Kehan; Musunuru, Kiran; Gerszten, Robert E; Wu, Sean M; Chen, Christopher S; Seidman, Jonathan G; Seidman, Christine E | Cell reports. | 28009297 | 2016 Dec 20; |
Mechanotransduction and Metabolism in Cardiomyocyte Microdomains. | Pasqualini, Francesco S; Nesmith, Alexander P; Horton, Renita E; Sheehy, Sean P; Parker, Kevin Kit | BioMed research international. | 28044126 | 2016; |
Inhibition of ?v?5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury. | McCurley, Amy; Alimperti, Stella; Campos-Bilderback, Silvia B; Sandoval, Ruben M; Calvino, Jenna E; Reynolds, Taylor L; Quigley, Catherine; Mugford, Joshua W; Polacheck, William J; Gomez, Ivan G; Dovey, Jennifer; Marsh, Graham; Huang, Angela; Qian, Fang; Weinreb, Paul H; Dolinski, Brian M; Moore, Shaun; Duffield, Jeremy S; Chen, Christopher S; Molitoris, Bruce A; Violette, Shelia M; Crackower, Michael A | Journal of the American Society of Nephrology : JASN. | 28062569 | 2017 Jun; |
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection. | Saxena, Kapil; Simon, Lukas M; Zeng, Xi-Lei; Blutt, Sarah E; Crawford, Sue E; Sastri, Narayan P; Karandikar, Umesh C; Ajami, Nadim J; Zachos, Nicholas C; Kovbasnjuk, Olga; Donowitz, Mark; Conner, Margaret E; Shaw, Chad A; Estes, Mary K | Proceedings of the National Academy of Sciences of the United States of America. | 28069942 | 2017 Jan 24; |
Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity. | Chang, Shih-Yu; Voellinger, Jenna L; Van Ness, Kirk P; Chapron, Brian; Shaffer, Rachel M; Neumann, Thomas; White, Collin C; Kavanagh, Terrance J; Kelly, Edward J; Eaton, David L | Toxicology in vitro : an international journal published in association with BIBRA. | 28089783 | 2017 Apr; |
A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications. | Phan, Duc T T; Wang, Xiaolin; Craver, Brianna M; Sobrino, Agua; Zhao, Da; Chen, Jerry C; Lee, Lilian Y N; George, Steven C; Lee, Abraham P; Hughes, Christopher C W | Lab on a chip. | 28092382 | 2017 01 31; |
21st Century Cell Culture for 21st Century Toxicology. | Pamies, David; Hartung, Thomas | Chemical research in toxicology. | 28092941 | 2017 01 17; |
Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms. | Shirure, V S; George, S C | Lab on a chip. | 28102869 | 2017 Feb 14; |
A conceptual model for the development process of confirmatory adaptive clinical trials within an emergency research network. | Mawocha, Samkeliso C; Fetters, Michael D; Legocki, Laurie J; Guetterman, Timothy C; Frederiksen, Shirley; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J | Clinical trials (London, England). | 28135827 | 2017 Jun; |
A versatile platform for surface modification of microfluidic droplets. | Li, Mingqiang; Jiang, Weiqian; Chen, Zaozao; Suryaprakash, Smruthi; Lv, Shixian; Tang, Zhaohui; Chen, Xuesi; Leong, Kam W | Lab on a chip. | 28154857 | 2017 Feb 14; |
Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. | Vernetti, Lawrence; Gough, Albert; Baetz, Nicholas; Blutt, Sarah; Broughman, James R; Brown, Jacquelyn A; Foulke-Abel, Jennifer; Hasan, Nesrin; In, Julie; Kelly, Edward; Kovbasnjuk, Olga; Repper, Jonathan; Senutovitch, Nina; Stabb, Janet; Yeung, Catherine; Zachos, Nick C; Donowitz, Mark; Estes, Mary; Himmelfarb, Jonathan; Truskey, George; Wikswo, John P; Taylor, D Lansing | Scientific reports. | 28176881 | 2017 Feb 08; |
Species-specific developmental timing is maintained by pluripotent stem cells ex utero. | Barry, Christopher; Schmitz, Matthew T; Jiang, Peng; Schwartz, Michael P; Duffin, Bret M; Swanson, Scott; Bacher, Rhonda; Bolin, Jennifer M; Elwell, Angela L; McIntosh, Brian E; Stewart, Ron; Thomson, James A | Developmental biology. | 28179190 | 2017 Mar 15; |
The molecular basis of endothelial cell plasticity. | Dejana, Elisabetta; Hirschi, Karen K; Simons, Michael | Nature communications. | 28181491 | 2017 Feb 09; |
The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology. | Yu, Huimin; Hasan, Nesrin M; In, Julie G; Estes, Mary K; Kovbasnjuk, Olga; Zachos, Nicholas C; Donowitz, Mark | Annual review of physiology. | 28192061 | 2017 Feb 10; |
Blood-brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood-central nervous system interface. | Phan, Duc Tt; Bender, R Hugh F; Andrejecsk, Jillian W; Sobrino, Agua; Hachey, Stephanie J; George, Steven C; Hughes, Christopher Cw | Experimental biology and medicine (Maywood, N.J.). | 28195514 | 2017 11; |
Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells. | Ghosh, Chaitali; Hossain, Mohammed; Solanki, Jesal; Najm, Imad M; Marchi, Nicola; Janigro, Damir | Epilepsia. | 28199000 | 2017 Apr; |
Biologically Relevant Heterogeneity: Metrics and Practical Insights. | Gough, Albert; Stern, Andrew M; Maier, John; Lezon, Timothy; Shun, Tong-Ying; Chennubhotla, Chakra; Schurdak, Mark E; Haney, Steven A; Taylor, D Lansing | SLAS discovery. | 28231035 | 2017 Mar; |
Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease. | Roach, Tracoyia; Alcendor, Donald J | Journal of neuroinflammation. | 28253931 | 2017 Mar 03; |
Laminar flow downregulates Notch activity to promote lymphatic sprouting. | Choi, Dongwon; Park, Eunkyung; Jung, Eunson; Seong, Young Jin; Yoo, Jaehyuk; Lee, Esak; Hong, Mingu; Lee, Sunju; Ishida, Hiroaki; Burford, James; Peti-Peterdi, Janos; Adams, Ralf H; Srikanth, Sonal; Gwack, Yousang; Chen, Christopher S; Vogel, Hans J; Koh, Chester J; Wong, Alex K; Hong, Young-Kwon | The Journal of clinical investigation. | 28263185 | 2017 Apr 03; |
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Biofunctionalized Plants as Diverse Biomaterials for Human Cell Culture. | Fontana, Gianluca; Gershlak, Joshua; Adamski, Michal; Lee, Jae-Sung; Matsumoto, Shion; Le, Hau D; Binder, Bernard; Wirth, John; Gaudette, Glenn; Murphy, William L | Advanced healthcare materials. | 28319334 | 2017 Apr; |
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A Genome-wide Analysis of Human Pluripotent Stem Cell-Derived Endothelial Cells in 2D or 3D Culture. | Zhang, Jue; Schwartz, Michael P; Hou, Zhonggang; Bai, Yongsheng; Ardalani, Hamisha; Swanson, Scott; Steill, John; Ruotti, Victor; Elwell, Angela; Nguyen, Bao Kim; Bolin, Jennifer; Stewart, Ron; Thomson, James A; Murphy, William L | Stem cell reports. | 28343999 | 2017 Apr 11; |
A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. | Xiao, Shuo; Coppeta, Jonathan R; Rogers, Hunter B; Isenberg, Brett C; Zhu, Jie; Olalekan, Susan A; McKinnon, Kelly E; Dokic, Danijela; Rashedi, Alexandra S; Haisenleder, Daniel J; Malpani, Saurabh S; Arnold-Murray, Chanel A; Chen, Kuanwei; Jiang, Mingyang; Bai, Lu; Nguyen, Catherine T; Zhang, Jiyang; Laronda, Monica M; Hope, Thomas J; Maniar, Kruti P; Pavone, Mary Ellen; Avram, Michael J; Sefton, Elizabeth C; Getsios, Spiro; Burdette, Joanna E; Kim, J Julie; Borenstein, Jeffrey T; Woodruff, Teresa K | Nature communications. | 28350383 | 2017 Mar 28; |
Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections. | Zou, Winnie Y; Blutt, Sarah E; Crawford, Sue E; Ettayebi, Khalil; Zeng, Xi-Lei; Saxena, Kapil; Ramani, Sasirekha; Karandikar, Umesh C; Zachos, Nicholas C; Estes, Mary K | Methods in molecular biology (Clifton, N.J.). | 28361480 | 2017 Mar 31; |
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Zika Virus Infection of the Human Glomerular Cells: Implications for Viral Reservoirs and Renal Pathogenesis. | Alcendor, Donald J | The Journal of infectious diseases | 28398522 | 2017 Jul 15 |
Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems. | Lee-Montiel, Felipe T; George, Subin M; Gough, Albert H; Sharma, Anup D; Wu, Juanfang; DeBiasio, Richard; Vernetti, Lawrence A; Taylor, D Lansing | Experimental biology and medicine (Maywood, N.J.). | 28409533 | 2017 Oct; |
WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue. | Loskill, Peter; Sezhian, Thiagarajan; Tharp, Kevin M; Lee-Montiel, Felipe T; Jeeawoody, Shaheen; Reese, Willie Mae; Zushin, Peter-James H; Stahl, Andreas; Healy, Kevin E | Lab on a chip. | 28418430 | 2017 May 02; |
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JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement. | Capulli, Andrew K; Emmert, Maximillian Y; Pasqualini, Francesco S; Kehl, Debora; Caliskan, Etem; Lind, Johan U; Sheehy, Sean P; Park, Sung Jin; Ahn, Seungkuk; Weber, Benedikt; Goss, Josue A; Hoerstrup, Simon P; Parker, Kevin Kit | Biomaterials. | 28445803 | 2017 Jul; |
Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems. | Soto-Gutierrez, Alejandro; Gough, Albert; Vernetti, Lawrence A; Taylor, D L; Monga, Satdarshan P | Experimental biology and medicine (Maywood, N.J.). | 28467181 | 2017 10; |
FGF-dependent metabolic control of vascular development. | Yu, Pengchun; Wilhelm, Kerstin; Dubrac, Alexandre; Tung, Joe K; Alves, Tiago C; Fang, Jennifer S; Xie, Yi; Zhu, Jie; Chen, Zehua; De Smet, Frederik; Zhang, Jiasheng; Jin, Suk-Won; Sun, Lele; Sun, Hongye; Kibbey, Richard G; Hirschi, Karen K; Hay, Nissim; Carmeliet, Peter; Chittenden, Thomas W; Eichmann, Anne; Potente, Michael; Simons, Michael | Nature. | 28467822 | 2017 05 11; |
A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice. | Laronda, Monica M; Rutz, Alexandra L; Xiao, Shuo; Whelan, Kelly A; Duncan, Francesca E; Roth, Eric W; Woodruff, Teresa K; Shah, Ramille N | Nature communications. | 28509899 | 2017 05 16; |
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Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques. | Barry, Christopher; Schmitz, Matthew T; Propson, Nicholas E; Hou, Zhonggang; Zhang, Jue; Nguyen, Bao K; Bolin, Jennifer M; Jiang, Peng; McIntosh, Brian E; Probasco, Mitchell D; Swanson, Scott; Stewart, Ron; Thomson, James A; Schwartz, Michael P; Murphy, William L | Experimental biology and medicine (Maywood, N.J.). | 28599598 | 2017 11; |
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Human iPS-derived endothelial cells for 3D microphysiological systems. | Kurokawa, Yosuke K; Yin, Rose T; Shang, Michael R; Shirure, Venktesh S; Moya, Monica L; George, Steven C | Tissue engineering. Part C, Methods. | 28622076 | 2017 Jun 16; |
3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels. | Wang, Xiaolin; Phan, Duc T T; George, Steven C; Hughes, Christopher C W; Lee, Abraham P | Methods in molecular biology (Clifton, N.J.). | 28634954 | 2017; |
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Integrated gut/liver microphysiological systems elucidates inflammatory inter-tissue crosstalk. | Chen, Wen L K; Edington, Collin; Suter, Emily; Yu, Jiajie; Velazquez, Jeremy J; Velazquez, Jason G; Shockley, Michael; Large, Emma M; Venkataramanan, Raman; Hughes, David J; Stokes, Cynthia L; Trumper, David L; Carrier, Rebecca L; Cirit, Murat; Griffith, Linda G; Lauffenburger, Douglas A | Biotechnology and bioengineering. | 28667746 | 2017 Jul 01; |
Functional characterization of human pluripotent stem cell-derived arterial endothelial cells. | Zhang, Jue; Chu, Li-Fang; Hou, Zhonggang; Schwartz, Michael P; Hacker, Timothy; Vickerman, Vernella; Swanson, Scott; Leng, Ning; Nguyen, Bao Kim; Elwell, Angela; Bolin, Jennifer; Brown, Matthew E; Stewart, Ron; Burlingham, William J; Murphy, William L; Thomson, James A | Proceedings of the National Academy of Sciences of the United States of America. | 28696312 | 2017 Jul 25; |
Detection of brain-directed autoantibodies in the serum of non-small cell lung cancer patients. | Banjara, Manoj; Ghosh, Chaitali; Dadas, Aaron; Mazzone, Peter; Janigro, Damir | PloS one. | 28746384 | 2017; |
Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies. | Tsamandouras, Nikolaos; Chen, Wen Li Kelly; Edington, Collin D; Stokes, Cynthia L; Griffith, Linda G; Cirit, Murat | The AAPS journal. | 28752430 | 2017 09; |
Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell-endothelial cell-regulated barrier function. | Alimperti, Stella; Mirabella, Teodelinda; Bajaj, Varnica; Polacheck, William; Pirone, Dana M; Duffield, Jeremy; Eyckmans, Jeroen; Assoian, Richard K; Chen, Christopher S | Proceedings of the National Academy of Sciences of the United States of America. | 28765370 | 2017 Aug 15; |
3D Differentiation of LUHMES Cell Line to Study Recovery and Delayed Neurotoxic Effects. | Harris, Georgina; Hogberg, Helena; Hartung, Thomas; Smirnova, Lena | Current protocols in toxicology. | 28777440 | 2017 Aug 04; |
Microphysiological Systems to Assess Nonclinical Toxicity. | Van Ness, Kirk P; Chang, Shih-Yu; Weber, Elijah J; Zumpano, Danielle; Eaton, David L; Kelly, Edward J | Current protocols in toxicology. | 28777442 | 2017 Aug 04; |
The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models. | Gough, Albert; Vernetti, Lawrence; Bergenthal, Luke; Shun, Tong Ying; Taylor, D Lansing | Applied in vitro toxicology. | 28781990 | 2016 Jun 01; |
Tissue Engineering the Vascular Tree. | Traore, Mahama A; George, Steven C | Tissue engineering. Part B, Reviews. | 28799844 | 2017 12; |
A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells. | Atchison, Leigh; Zhang, Haoyue; Cao, Kan; Truskey, George A | Scientific reports. | 28811655 | 2017 08 15; |
Myofibrils in Cardiomyocytes Tend to Assemble Along the Maximal Principle Stress Directions. | Yuan, Hongyan; Marzban, Bahador; Kit Parker, Kevin | Journal of biomechanical engineering | 28857113 | 2017 Dec 01 |
Engineered Microvasculature in PDMS Networks Using Endothelial Cells Derived from Human Induced Pluripotent Stem Cells. | Sivarapatna, Amogh; Ghaedi, Mahboobe; Xiao, Yang; Han, Edward; Aryal, Binod; Zhou, Jing; Fernandez-Hernando, Carlos; Qyang, Yibing; Hirschi, Karen K; Niklason, Laura E | Cell transplantation. | 28901188 | 2017 08; |
RNA-Seq of Human Neural Progenitor Cells Exposed to Lead (Pb) Reveals Transcriptome Dynamics, Splicing Alterations and Disease Risk Associations. | Jiang, Peng; Hou, Zhonggang; Bolin, Jennifer M; Thomson, James A; Stewart, Ron | Toxicological sciences : an official journal of the Society of Toxicology. | 28903495 | 2017 Sep 01; |
In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4(+) T Lymphocytes. | Matta, Poojitha; Sherrod, Stacy D; Marasco, Christina C; Moore, Daniel J; McLean, John A; Weitkamp, Joern-Hendrik | Journal of immunology (Baltimore, Md. : 1950). | 28947540 | 2017 Nov 01; |
Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease. | Cruz, Nelly M; Song, Xuewen; Czerniecki, Stefan M; Gulieva, Ramila E; Churchill, Angela J; Kim, Yong Kyun; Winston, Kosuke; Tran, Linh M; Diaz, Marco A; Fu, Hongxia; Finn, Laura S; Pei, York; Himmelfarb, Jonathan; Freedman, Benjamin S | Nature materials. | 28967916 | 2017 Nov; |
Cancer-associated fibroblasts support vascular growth through mechanical force. | Sewell-Loftin, Mary Kathryn; Bayer, Samantha Van Hove; Crist, Elizabeth; Hughes, Taylor; Joison, Sofia M; Longmore, Gregory D; George, Steven C | Scientific reports. | 28974764 | 2017 Oct 03; |
Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening. | Lind, Johan U; Yadid, Moran; Perkins, Ian; O'Connor, Blakely B; Eweje, Feyisayo; Chantre, Christophe O; Hemphill, Matthew A; Yuan, Hongyan; Campbell, Patrick H; Vlassak, Joost J; Parker, Kevin K | Lab on a chip. | 28976521 | 2017 Oct 25; |
Cationic Nanocylinders Promote Angiogenic Activities of Endothelial Cells. | Lee, Jung Bok; Balikov, Daniel A; Yang, Jae Won; Kim, Ki Seok; Park, Hun Kuk; Kim, Jeong Koo; Kwon, Il Keun; Bellan, Leon M; Sung, Hak-Joon | Polymers. | 29034114 | 2016 Jan; |
Biomechanical regulation of drug sensitivity in an engineered model of human tumor. | Marturano-Kruik, A; Villasante, A; Yaeger, K; Ambati, S R; Chramiec, A; Raimondi, M T; Vunjak-Novakovic, G | Biomaterials. | 29040875 | 2018 Jan; |
MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock. | Kader, Muhamuda; Alaoui-El-Azher, Mounia; Vorhauer, Jennie; Kode, Bhushan B; Wells, Jakob Z; Stolz, Donna; Michalopoulos, George; Wells, Alan; Scott, Melanie; Ismail, Nahed | PLoS pathogens. | 29049365 | 2017 Oct; |
Concise Review: Current and Emerging Biomarkers of Nephrotoxicity. | Weber, Elijah J; Himmelfarb, Jonathan; Kelly, Edward J | Current opinion in toxicology. | 29057384 | 2017 Jun; |
Circadian hormone control in a human-on-a-chip: In vitro biology's ignored component? | Cyr, Kevin J; Avaldi, Omero M; Wikswo, John P | Experimental biology and medicine (Maywood, N.J.). | 29065796 | 2017 Nov; |
Self-contained, low-cost Body-on-a-Chip systems for drug development. | Wang, Ying I; Oleaga, Carlota; Long, Christopher J; Esch, Mandy B; McAleer, Christopher W; Miller, Paula G; Hickman, James J; Shuler, Michael L | Experimental biology and medicine (Maywood, N.J.). | 29065797 | 2017 11; |
Microphysiologic systems in female reproductive biology. | Young, Alexandria N; Moyle-Heyrman, Georgette; Kim, J Julie; Burdette, Joanna E | Experimental biology and medicine (Maywood, N.J.). | 29065798 | 2017 11; |
Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology. | Watson, David E; Hunziker, Rosemarie; Wikswo, John P | Experimental biology and medicine (Maywood, N.J.). | 29065799 | 2017 Oct; |
Application of induced pluripotent stem cells to model smooth muscle cell function in vascular diseases. | Ji, HaYeun; Kim, Hye Sung; Kim, Hae-Won; Leong, Kam W | Current opinion in biomedical engineering. | 29082353 | 2017 Mar; |
The life cycles of six multi-center adaptive clinical trials focused on neurological emergencies developed for the Advancing Regulatory Science initiative of the National Institutes of Health and US Food and Drug Administration: Case studies from the Adap | Guetterman, Timothy C; Fetters, Michael D; Mawocha, Samkeliso; Legocki, Laurie J; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J | SAGE open medicine. | 29085638 | 2017; |
Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion. | Nguyen, Eric H; Daly, William T; Le, Ngoc Nhi T; Farnoodian, Mitra; Belair, David G; Schwartz, Michael P; Lebakken, Connie S; Ananiev, Gene E; Saghiri, Mohammad Ali; Knudsen, Thomas B; Sheibani, Nader; Murphy, William L | Nature biomedical engineering. | 29104816 | 2017; |
Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells. | Dioufa, Nikolina; Clark, Amanda M; Ma, Bo; Beckwitt, Colin H; Wells, Alan | Molecular cancer. | 29137633 | 2017 Nov 14; |
Biomarker identification for statin sensitivity of cancer cell lines. | Raghu, Vineet K; Beckwitt, Colin H; Warita, Katsuhiko; Wells, Alan; Benos, Panayiotis V; Oltvai, Zoltán N | Biochemical and biophysical research communications. | 29146185 | 2018 01 01; |
Executive summary of the 12th HHT international scientific conference. | Andrejecsk, Jillian W; Hosman, Anna E; Botella, Luisa M; Shovlin, Claire L; Arthur, Helen M; Dupuis-Girod, Sophie; Buscarini, Elisabetta; Hughes, Christopher C W; Lebrin, Franck; Mummery, Christine L; Post, Marco C; Mager, Johannes J | Angiogenesis | 29147802 | 2018 02 |
Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma. | Villasante, A; Sakaguchi, K; Kim, J; Cheung, N K; Nakayama, M; Parsa, H; Okano, T; Shimizu, T; Vunjak-Novakovic, G | Theranostics. | 29158813 | 2017; |
A non-canonical Notch complex regulates adherens junctions and vascular barrier function. | Polacheck, William J; Kutys, Matthew L; Yang, Jinling; Eyckmans, Jeroen; Wu, Yinyu; Vasavada, Hema; Hirschi, Karen K; Chen, Christopher S | Nature. | 29160307 | 2017 12 14; |
Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy. | Khazali, Ahmad S; Clark, Amanda M; Wells, Alan | British journal of cancer. | 29169181 | 2018 Feb 20; |
Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. | Chang, Shih-Yu; Weber, Elijah J; Sidorenko, Viktoriya S; Chapron, Alenka; Yeung, Catherine K; Gao, Chunying; Mao, Qingcheng; Shen, Danny; Wang, Joanne; Rosenquist, Thomas A; Dickman, Kathleen G; Neumann, Thomas; Grollman, Arthur P; Kelly, Edward J; Himmel | JCI insight. | 29202460 | 2017 Nov 16; |
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. | Fang, Jennifer S; Coon, Brian G; Gillis, Noelle; Chen, Zehua; Qiu, Jingyao; Chittenden, Thomas W; Burt, Janis M; Schwartz, Martin A; Hirschi, Karen K | Nature communications. | 29247167 | 2017 12 15; |
Liver 'organ on a chip'. | Beckwitt, Colin H; Clark, Amanda M; Wheeler, Sarah; Taylor, D Lansing; Stolz, Donna B; Griffith, Linda; Wells, Alan | Experimental cell research. | 29291400 | 2018 02 01; |
Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes. | Jia, Shanhang; Miedel, Mark T; Ngo, Marilyn; Hessenius, Ryan; Chen, Ning; Wang, Peilu; Bahreini, Amir; Li, Zheqi; Ding, Zhijie; Shun, Tong Ying; Zuckerman, Daniel M; Taylor, D Lansing; Puhalla, Shannon L; Lee, Adrian V; Oesterreich, Steffi; Stern, Andrew M | Oncology. | 29306943 | 2018 Jan 06; |
Engineering human pluripotent stem cells into a functional skeletal muscle tissue. | Rao, Lingjun; Qian, Ying; Khodabukus, Alastair; Ribar, Thomas; Bursac, Nenad | Nature communications. | 29317646 | ; |
Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications. | Nawroth, Janna C; Scudder, Lisa L; Halvorson, Ryan T; Tresback, Jason; Ferrier, John P; Sheehy, Sean P; Cho, Alex; Kannan, Suraj; Sunyovszki, Ilona; Goss, Josue A; Campbell, Patrick H; Parker, Kevin Kit | Biofabrication. | 29337695 | 2018 Jan 16; |
A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures. | Clark, Amanda M; Kumar, Manu P; Wheeler, Sarah E; Young, Carissa L; Venkataramanan, Raman; Stolz, Donna B; Griffith, Linda G; Lauffenburger, Douglas A; Wells, Alan | Molecular & cellular proteomics : MCP. | 29353230 | 2018 Apr; |
Human bone perivascular niche-on-a-chip for studying metastatic colonization. | Marturano-Kruik, Alessandro; Nava, Michele Maria; Yeager, Keith; Chramiec, Alan; Hao, Luke; Robinson, Samuel; Guo, Edward; Raimondi, Manuela Teresa; Vunjak-Novakovic, Gordana | Proceedings of the National Academy of Sciences of the United States of America. | 29363599 | 2018 Feb 06; |
The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms. | Kang, Inhae; Chu, Charleen T; Kaufman, Brett A | FEBS letters. | 29364506 | 2018 Mar; |
Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues. | Karolak, Aleksandra; Markov, Dmitry A; McCawley, Lisa J; Rejniak, Katarzyna A | Journal of the Royal Society, Interface. | 29367239 | 2018 Jan; |
Rotenone exerts developmental neurotoxicity in a human brain spheroid model. | Pamies, David; Block, Katharina; Lau, Pierre; Gribaldo, Laura; Pardo, Carlos A; Barreras, Paula; Smirnova, Lena; Wiersma, Daphne; Zhao, Liang; Harris, Georgina; Hartung, Thomas; Hogberg, Helena T | Toxicology and applied pharmacology. | 29428530 | 2018 09 01; |
Multidrug Resistance Protein 1 Deficiency Promotes Doxorubicin-Induced Ovarian Toxicity in Female Mice. | Wang, Yingzheng; Liu, Mingjun; Zhang, Jiyang; Liu, Yuwen; Kopp, Megan; Zheng, Weiwei; Xiao, Shuo | Toxicological sciences : an official journal of the Society of Toxicology. | 29462422 | 2018 May 01; |
Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. | Ronaldson-Bouchard, Kacey; Vunjak-Novakovic, Gordana | Cell stem cell. | 29499151 | 2018 03 01; |
Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cells. | Hoang, Plansky; Wang, Jason; Conklin, Bruce R; Healy, Kevin E; Ma, Zhen | Nature protocols. | 29543795 | 2018 Apr; |
Traction force microscopy of engineered cardiac tissues. | Pasqualini, Francesco Silvio; Agarwal, Ashutosh; O'Connor, Blakely Bussie; Liu, Qihan; Sheehy, Sean P; Parker, Kevin Kit | PloS one. | 29590169 | 2018; |
Multifaceted Roles of Connexin 43 in Stem Cell Niches. | Genet, Nafiisha; Bhatt, Neha; Bourdieu, Antonin; Hirschi, Karen K | Current stem cell reports. | 29600160 | 2018; |
Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment. | Kotha, Surya; Sun, Sijie; Adams, Amie; Hayes, Brian; Phong, Kiet T; Nagao, Ryan; Reems, Jo-Anna; Gao, Dayong; Torok-Storb, Beverly; López, José A; Zheng, Ying | PloS one. | 29617409 | 2018; |
Advanced maturation of human cardiac tissue grown from pluripotent stem cells. | Ronaldson-Bouchard, Kacey; Ma, Stephen P; Yeager, Keith; Chen, Timothy; Song, LouJin; Sirabella, Dario; Morikawa, Kumi; Teles, Diogo; Yazawa, Masayuki; Vunjak-Novakovic, Gordana | Nature. | 29618819 | 2018 Apr; |
Human organoid cultures: transformative new tools for human virus studies. | Ramani, Sasirekha; Crawford, Sue E; Blutt, Sarah E; Estes, Mary K | Current opinion in virology. | 29656244 | 2018 Apr; |
Quantitatively characterizing drug-induced arrhythmic contractile motions of human stem cell-derived cardiomyocytes. | Hoang, Plansky; Huebsch, Nathaniel; Bang, Shin Hyuk; Siemons, Brian A; Conklin, Bruce R; Healy, Kevin E; Ma, Zhen; Jacquir, Sabir | Biotechnology and bioengineering. | 29663322 | 2018 08; |
Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases. | Blutt, Sarah E; Crawford, Sue E; Ramani, Sasirekha; Zou, Winnie Y; Estes, Mary K | Cellular and molecular gastroenterology and hepatology. | 29675450 | 2018 Mar; |
3S - Systematic, systemic, and systems biology and toxicology. | Smirnova, Lena; Kleinstreuer, Nicole; Corvi, Raffaella; Levchenko, Andre; Fitzpatrick, Suzanne C; Hartung, Thomas | ALTEX. | 29677694 | 2018; |
Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide. | Wang, Hong-Xia; Song, Ziyuan; Lao, Yeh-Hsing; Xu, Xin; Gong, Jing; Cheng, Du; Chakraborty, Syandan; Park, Ji Sun; Li, Mingqiang; Huang, Dantong; Yin, Lichen; Cheng, Jianjun; Leong, Kam W | Proceedings of the National Academy of Sciences of the United States of America. | 29686087 | 2018 May 08; |
In Vitro Tissue-Engineered Skeletal Muscle Models for Studying Muscle Physiology and Disease. | Khodabukus, Alastair; Prabhu, Neel; Wang, Jason; Bursac, Nenad | Advanced healthcare materials. | 29696831 | 2018 08; |
RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. | Thakore, Pratiksha I; Kwon, Jennifer B; Nelson, Christopher E; Rouse, Douglas C; Gemberling, Matthew P; Oliver, Matthew L; Gersbach, Charles A | Nature communications. | 29700298 | 2018 Apr 26; |
A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis. | Miller, Chris P; Tsuchida, Connor; Zheng, Ying; Himmelfarb, Jonathan; Akilesh, Shreeram | Neoplasia (New York, N.Y.). | 29747161 | 2018 06; |
Tissue engineering toward organ-specific regeneration and disease modeling. | Mandrycky, Christian; Phong, Kiet; Zheng, Ying | MRS communications. | 29750131 | 2017 Sep; |
Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling. | Beckwitt, Colin H; Shiraha, Keisuke; Wells, Alan | PloS one. | 29763460 | 2018; |
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping. | Czerniecki, Stefan M; Cruz, Nelly M; Harder, Jennifer L; Menon, Rajasree; Annis, James; Otto, Edgar A; Gulieva, Ramila E; Islas, Laura V; Kim, Yong Kyun; Tran, Linh M; Martins, Timothy J; Pippin, Jeffrey W; Fu, Hongxia; Kretzler, Matthias; Shankland, Stuart J; Himmelfarb, Jonathan; Moon, Randall T; Paragas, Neal; Freedman, Benjamin S | Cell stem cell. | 29779890 | 2018 Jun 01; |
Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies. | Maass, Christian; Dallas, Matthew; LaBarge, Matthew E; Shockley, Michael; Valdez, Jorge; Geishecker, Emily; Stokes, Cynthia L; Griffith, Linda G; Cirit, Murat | Scientific reports. | 29789564 | 2018 May 22; |
A pumpless body-on-a-chip model using a primary culture of human intestinal cells and a 3D culture of liver cells. | Chen, Huanhuan Joyce; Miller, Paula; Shuler, Michael L | Lab on a chip. | 29881844 | 2018 07 10; |
Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications. | Adamski, Michal; Fontana, Gianluca; Gershlak, Joshua R; Gaudette, Glenn R; Le, Hau D; Murphy, William L | Journal of visualized experiments : JoVE. | 29912197 | 2018 05 31; |
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Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers. | Yin, Jianyi; Tse, Chung-Ming; Avula, Leela Rani; Singh, Varsha; Foulke-Abel, Jennifer; de Jonge, Hugo R; Donowitz, Mark | Cellular and molecular gastroenterology and hepatology. | 29930980 | 2018; |
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A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX. | Li, Xiang; George, Subin M; Vernetti, Lawrence; Gough, Albert H; Taylor, D Lansing | Lab on a chip. | 30063238 | 2018 08 21; |
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Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system. | Oleaga, Carlota; Riu, Anne; Rothemund, Sandra; Lavado, Andrea; McAleer, Christopher W; Long, Christopher J; Persaud, Keisha; Narasimhan, Narasimhan Sriram; Tran, My; Roles, Jeffry; Carmona-Moran, Carlos A; Sasserath, Trevor; Elbrecht, Daniel H; Kumanchik, Lee; Bridges, L Richard; Martin, Candace; Schnepper, Mark T; Ekman, Gail; Jackson, Max; Wang, Ying I; Note, Reine; Langer, Jessica; Teissier, Silvia; Hickman, James J | Biomaterials. | 30130706 | 2018 11; |
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Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip. | Sakolish, Courtney; Weber, Elijah J; Kelly, Edward J; Himmelfarb, Jonathan; Mouneimne, Roula; Grimm, Fabian A; House, John S; Wade, Terry; Han, Arum; Chiu, Weihsueh A; Rusyn, Ivan | Scientific reports. | 30291268 | 2018 10 05; |
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A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation. | Monteiro, Maria B; Ramm, Susanne; Chandrasekaran, Vidya; Boswell, Sarah A; Weber, Elijah J; Lidberg, Kevin A; Kelly, Edward J; Vaidya, Vishal S | Journal of the American Society of Nephrology : JASN. | 30361326 | 2018 12; |
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Engineering a Bioartificial Human Colon Model Through Decellularization and Recellularization. | Chen, Huanhuan Joyce; Shuler, Michael L | Methods in molecular biology (Clifton, N.J.). | 30542993 | 2019; |
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Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels. | Kaushik, Gaurav; Gil, Daniel A; Torr, Elizabeth; Berge, Elizabeth S; Soref, Cheryl; Uhl, Peyton; Fontana, Gianluca; Antosiewicz-Bourget, Jessica; Edington, Collin; Schwartz, Michael P; Griffith, Linda G; Thomson, James A; Skala, Melissa C; Daly, William T; Murphy, William L | Advanced healthcare materials. | 30565891 | 2019 01; |
Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity. | Weber, Elijah J; Lidberg, Kevin A; Wang, Lu; Bammler, Theo K; MacDonald, James W; Li, Mavis J; Redhair, Michelle; Atkins, William M; Tran, Cecilia; Hines, Kelly M; Herron, Josi; Xu, Libin; Monteiro, Maria Beatriz; Ramm, Susanne; Vaidya, Vishal; Vaara, Martti; Vaara, Timo; Himmelfarb, Jonathan; Kelly, Edward J | JCI insight. | 30568031 | 2018 12 20; |
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A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis. | Natividad-Diaz, Sylvia L; Browne, Shane; Jha, Amit K; Ma, Zhen; Hossainy, Samir; Kurokawa, Yosuke K; George, Steven C; Healy, Kevin E | Biomaterials. | 30583150 | 2019 Feb; |
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Translational Assessment of Drug-Induced Proximal Tubule Injury Using a Kidney Microphysiological System. | Maass, Christian; Sorensen, Nathan B; Himmelfarb, Jonathan; Kelly, Edward J; Stokes, Cynthia L; Cirit, Murat | CPT: pharmacometrics & systems pharmacology. | 30869201 | 2019 05; |
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Modeling the Effect of TNF-? upon Drug-Induced Toxicity in Human, Tissue-Engineered Myobundles. | Davis, Brittany N J; Santoso, Jeffrey W; Walker, Michaela J; Oliver, Catherine E; Cunningham, Michael M; Boehm, Christian A; Dawes, Danielle; Lasater, Samantha L; Huffman, Kim; Kraus, William E; Truskey, George A | Annals of biomedical engineering. | 30963383 | 2019 Jul; |
A tissue-engineered scale model of the heart ventricle. | MacQueen, Luke A; Sheehy, Sean P; Chantre, Christophe O; Zimmerman, John F; Pasqualini, Francesco S; Liu, Xujie; Goss, Josue A; Campbell, Patrick H; Gonzalez, Grant M; Park, Sung-Jin; Capulli, Andrew K; Ferrier, John P; Kosar, T Fettah; Mahadevan, L; Pu, William T; Parker, Kevin Kit | Nature biomedical engineering. | 31015723 | 2018 12; |
Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload. | Ma, Zhen; Huebsch, Nathaniel; Koo, Sangmo; Mandegar, Mohammad A; Siemons, Brian; Boggess, Steven; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin E | Nature biomedical engineering. | 31015724 | 2018 12; |
A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia. | Zhang, Jue; McIntosh, Brian E; Wang, Bowen; Brown, Matthew E; Probasco, Mitchell D; Webster, Sarah; Duffin, Bret; Zhou, Ying; Guo, Lian-Wang; Burlingham, William J; Kent, Craig; Ferris, Michael; Thomson, James A | Stem cell reports. | 31080110 | 2019 Jun 11; |
Adult Stem Cell Functioning in the Tumor Micro-Environment. | Jiang, Yuhan; Wells, Alan; Sylakowski, Kyle; Clark, Amanda M; Ma, Bo | International journal of molecular sciences | 31130595 | 2019 May 25 |
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An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells. | Chu, Li-Fang; Mamott, Daniel; Ni, Zijian; Bacher, Rhonda; Liu, Cathy; Swanson, Scott; Kendziorski, Christina; Stewart, Ron; Thomson, James A | Cell reports. | 31461642 | 2019 Aug 27; |
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Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype. | Ronaldson-Bouchard, Kacey; Yeager, Keith; Teles, Diogo; Chen, Timothy; Ma, Stephen; Song, LouJin; Morikawa, Kumi; Wobma, Holly M; Vasciaveo, Alessandro; Ruiz, Edward C; Yazawa, Masayuki; Vunjak-Novakovic, Gordana | Nature protocols. | 31492957 | 2019 10; |
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Glucose Uptake and Insulin Response in Tissue-engineered Human Skeletal Muscle. | Kondash, Megan E; Ananthakumar, Anandita; Khodabukus, Alastair; Bursac, Nenad; Truskey, George A | Tissue engineering and regenerative medicine. | 32200516 | 2020 Mar 21; |
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial. | Chamberlain, James M; Kapur, Jaideep; Shinnar, Shlomo; Elm, Jordan; Holsti, Maija; Babcock, Lynn; Rogers, Alex; Barsan, William; Cloyd, James; Lowenstein, Daniel; Bleck, Thomas P; Conwit, Robin; Meinzer, Caitlyn; Cock, Hannah; Fountain, Nathan B; Underwoo | Lancet (London, England). | 32203691 | 2020 04 11; |
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Oligoproline-derived nanocarrier for dual stimuli-responsive gene delivery. | Gupta, Mukesh K; Lee, Sue Hyun; Crowder, Spencer W; Wang, Xintong; Hofmeister, Lucas H; Nelson, Christopher E; Bellan, Leon M; Duvall, Craig L; Sung, Hak-Joon | Journal of materials chemistry. B | 32262835 | 2015 Sep 28 |
Tissue-Engineered Human Myobundle System as a Platform for Evaluation of Skeletal Muscle Injury Biomarkers. | Khodabukus, Alastair; Kaza, Amulya; Wang, Jason; Prabhu, Neel; Goldstein, Richard; Vaidya, Vishal S; Bursac, Nenad | Toxicological sciences : an official journal of the Society of Toxicology. | 32294208 | 2020 Jul 01; |
Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection. | Foulke-Abel, Jennifer; Yu, Huimin; Sunuwar, Laxmi; Lin, Ruxian; Fleckenstein, James M; Kaper, James B; Donowitz, Mark | Gut microbes. | 32378997 | 2020 May 07; |
Testicular organoid formation is a property of immature somatic cells, which self-assemble and exhibit long-term hormone-responsive endocrine function. | Edmonds, Maxwell E; Woodruff, Teresa K | Biofabrication. | 32492667 | 2020 07 09; |
Integrative microphysiological tissue systems of cancer metastasis to the liver. | Clark, Amanda M; Allbritton, Nancy L; Wells, Alan | Seminars in cancer biology. | 32580025 | 2020 Jun 21; |
Distinct follicular and luteal transcriptional profiles in engineered human ectocervical tissue dependent on menstrual cycle phase. | McKinnon, Kelly E; Getsios, Spiro; Woodruff, Teresa K | Biology of reproduction | 32614039 | 2020 08 21 |
Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes. | Bhatraju, Pavan K; Cohen, Max; Nagao, Ryan J; Morrell, Eric D; Kosamo, Susanna; Chai, Xin-Ya; Nance, Robin; Dmyterko, Victoria; Delaney, Joseph; Christie, Jason D; Liu, Kathleen D; Mikacenic, Carmen; Gharib, Sina A; Liles, W Conrad; Zheng, Ying; Christiani, David C; Himmelfarb, Jonathan; Wurfel, Mark M | BMC nephrology | 32680471 | 2020 07 17 |
Continuous Formation of Ultrathin, Strong Collagen Sheets with Tunable Anisotropy and Compaction. | Malladi, Shashi; Miranda-Nieves, David; Leng, Lian; Grainger, Stephanie J; Tarabanis, Constantine; Nesmith, Alexander P; Kosaraju, Revanth; Haller, Carolyn A; Parker, Kevin Kit; Chaikof, Elliot L; Günther, Axel | ACS biomaterials science & engineering | 32685675 | 2020 07 13 |
A functional long-term 2D serum-free human hepatic in vitro system for drug evaluation. | Oleaga, Carlota; Bridges, L Richard; Persaud, Keisha; McAleer, Christopher W; Long, Christopher J; Hickman, James J | Biotechnology progress | 32829524 | 2021 01 |
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Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs. | Liu, Yizhong; Sakolish, Courtney; Chen, Zunwei; Phan, Duc T T; Bender, R Hugh F; Hughes, Christopher C W; Rusyn, Ivan | Toxicology. | 32980478 | 2020 Dec 01; |
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Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip. | Yadid, Moran; Lind, Johan U; Ardoña, Herdeline Ann M; Sheehy, Sean P; Dickinson, Lauren E; Eweje, Feyisayo; Bastings, Maartje M C; Pope, Benjamin; O'Connor, Blakely B; Straubhaar, Juerg R; Budnik, Bogdan; Kleber, Andre G; Parker, Kevin Kit | Science translational medicine | 33055246 | 2020 10 14 |
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Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification. | Qiu, Jingyao; Nordling, Sofia; Vasavada, Hema H; Butcher, Eugene C; Hirschi, Karen K | Cell reports | 33264627 | 2020 Dec 01 |
Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS). | Sakolish, Courtney; Reese, Celeste E; Luo, Yu-Syuan; Valdiviezo, Alan; Schurdak, Mark E; Gough, Albert; Taylor, D Lansing; Chiu, Weihsueh A; Vernetti, Lawrence A; Rusyn, Ivan | Toxicology | 33307106 | 2021 01 30 |
Electroencephalographic Seizures in Emergency Department Patients After Treatment for Convulsive Status Epilepticus. | Zehtabchi, Shahriar; Silbergleit, Robert; Chamberlain, James M; Shinnar, Shlomo; Elm, Jordan J; Underwood, Ellen; Rosenthal, Eric S; Bleck, Thomas P; Kapur, Jaideep | Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society | 33337664 | 2020 Dec 11 |
Modeling the Complexity of the Metastatic Niche Ex Vivo. | Clark, Amanda M | Methods in molecular biology (Clifton, N.J.) | 33340364 | 2021 |
A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®. | Bircsak, Kristin M; DeBiasio, Richard; Miedel, Mark; Alsebahi, Alaa; Reddinger, Ryan; Saleh, Anthony; Shun, Tongying; Vernetti, Lawrence A; Gough, Albert | Toxicology | 33359578 | 2021 Feb 28 |
An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy. | Hachey, Stephanie J; Movsesyan, Silva; Nguyen, Quy H; Burton-Sojo, Giselle; Tankazyan, Ani; Wu, Jie; Hoang, Tuyen; Zhao, Da; Wang, Shuxiong; Hatch, Michaela M; Celaya, Elizabeth; Gomez, Samantha; Chen, George T; Davis, Ryan T; Nee, Kevin; Pervolarakis, Nicholas; Lawson, Devon A; Kessenbrock, Kai; Lee, Abraham P; Lowengrub, John; Waterman, Marian L; Hughes, Christopher C W | Lab on a chip | 33605955 | 2021 04 07 |
Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues. | Song, H-H Greco; Lammers, Alex; Sundaram, Subramanian; Rubio, Logan; Chen, Amanda X; Li, Linqing; Eyckmans, Jeroen; Bhatia, Sangeeta N; Chen, Christopher S | Advanced functional materials | 33613149 | 2020 Nov 25 |
Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease. | Lidberg, Kevin A; Annalora, Andrew J; Jozic, Marija; Elson, Daniel J; Wang, Lu; Bammler, Theo K; Ramm, Susanne; Monteiro, Maria Beatriz; Himmelfarb, Jonathan; Marcus, Craig B; Iversen, Patrick L; Kelly, Edward J | Scientific reports | 33633318 | 2021 Feb 25 |
Interspecies chimeric conditions affect the developmental rate of human pluripotent stem cells. | Brown, Jared; Barry, Christopher; Schmitz, Matthew T; Argus, Cara; Bolin, Jennifer M; Schwartz, Michael P; Van Aartsen, Amy; Steill, John; Swanson, Scott; Stewart, Ron; Thomson, James A; Kendziorski, Christina | PLoS computational biology | 33647016 | 2021 03 |
Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling. | Mina, Sara G; Alaybeyoglu, Begum; Murphy, William L; Thomson, James A; Stokes, Cynthia L; Cirit, Murat | Frontiers in big data | 33693346 | 2019 |
Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers. | Chen, Amanda X; Chhabra, Arnav; Song, H-H Greco; Fleming, Heather E; Chen, Christopher S; Bhatia, Sangeeta N | Advanced functional materials | 33776613 | 2020 Nov 25 |
Vascular endothelial cell specification in health and disease. | Marziano, Corina; Genet, Gael; Hirschi, Karen K | Angiogenesis | 33844116 | 2021 Apr 12 |
Directed Differentiation of Hemogenic Endothelial Cells from Human Pluripotent Stem Cells. | Nelson, Elizabeth A; Qiu, Jingyao; Chavkin, Nicholas W; Hirschi, Karen K | Journal of visualized experiments : JoVE | 33871448 | 2021 03 31 |
Early Neurologic Recovery, Practice Pattern Variation, and the Risk of Endotracheal Intubation Following Established Status Epilepticus. | Rosenthal, Eric S; Elm, Jordan J; Ingles, James; Rogers, Alexander J; Terndrup, Thomas E; Holsti, Maija; Thomas, Danny G; Babcock, Lynn; Okada, Pamela J; Lipsky, Robert H; Miller, Joseph B; Hickey, Robert W; Barra, Megan E; Bleck, Thomas P; Cloyd, James C; Silbergleit, Robert; Lowenstein, Daniel H; Coles, Lisa D; Kapur, Jaideep; Shinnar, Shlomo; Chamberlain, James M; Established Status Epilepticus Treatment Trial Study Group | Neurology | 34032604 | 2021 05 11 |
Platforms to test the temporospatial capabilities of carrier systems in delivering growth factors to benefit vascular bioengineering. | Argueta, Lissenya B; Niles, Jean A; Sakamoto, Jason; Liu, Xuewu; Vega, Stephanie P; Frank, Luba; Paessler, Marco; Cortiella, Joaquin; Nichols, Joan E | Nanomedicine : nanotechnology, biology, and medicine | 34147665 | 2021 08 |
The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation. | Chavkin, Nicholas W; Sano, Soichi; Wang, Ying; Oshima, Kosei; Ogawa, Hayato; Horitani, Keita; Sano, Miho; MacLauchlan, Susan; Nelson, Anders; Setia, Karishma; Vippa, Tanvi; Watanabe, Yosuke; Saucerman, Jeffrey J; Hirschi, Karen K; Gokce, Noyan; Walsh, Kenneth | Journal of the American Heart Association | 34155901 | 2021 07 06 |
Non-destructive vacuum-assisted measurement of lung elastic modulus. | Chen, Jiawen; Mir, Seyed Mohammad; Pinezich, Meghan R; O'Neill, John D; Guenthart, Brandon A; Bacchetta, Matthew; Vunjak-Novakovic, Gordana; Huang, Sarah X L; Kim, Jinho | Acta biomaterialia | 34192570 | 2021 Sep 01 |
A High-Throughput Mechanical Activator for Cartilage Engineering Enables Rapid Screening of in vitro Response of Tissue Models to Physiological and Supra-Physiological Loads. | Capuana, Elisa; Marino, Davide; Di Gesù, Roberto; La Carrubba, Vincenzo; Brucato, Valerio; Tuan, Rocky S; Gottardi, Riccardo | Cells, tissues, organs | 34261061 | 2022 |
Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation. | Blutt, Sarah E; Crawford, Sue E; Bomidi, Carolyn; Zeng, Xi-Lei; Broughman, James R; Robertson, Matthew; Coarfa, Cristian; Tessier, Mary Elizabeth M; Savidge, Tor; Hollinger, F Blaine; Curley, Steven A; Donowitz, Mark; Estes, Mary K | American journal of physiology. Gastrointestinal and liver physiology | 34288725 | 2021 09 01 |
The vascular niche in next generation microphysiological systems. | Ewald, Makena L; Chen, Yu-Hsi; Lee, Abraham P; Hughes, Christopher C W | Lab on a chip | 34396383 | 2021 09 07 |
High resolution stereolithography fabrication of perfusable scaffolds to enable long-term meso-scale hepatic culture for disease modeling. | Sphabmixay, Pierre; Raredon, Micha Sam Brickman; Wang, Alex J-S; Lee, Howon; Hammond, Paula T; Fang, Nicholas X; Griffith, Linda G | Biofabrication | 34479229 | 2021 09 21 |
Understanding neural stem cell regulation in vivo and applying the insights to cell therapy for strokes. | Genet, Nafiisha; Hirschi, Karen K | Regenerative medicine | 34498495 | 2021 09 |
A Mesoscale 3D Culture System for Native and Engineered Biphasic Tissues: Application to the Osteochondral Unit. | Chiesa, Irene; Di Gesù, Roberto; Overholt, Kalon J; Gottardi, Riccardo | Methods in molecular biology (Clifton, N.J.) | 34520018 | 2022 |
Prediction of hepatic drug clearance with a human microfluidic four-cell liver acinus microphysiology system. | Sakolish, Courtney; Luo, Yu-Syuan; Valdiviezo, Alan; Vernetti, Lawrence A; Rusyn, Ivan; Chiu, Weihsueh A | Toxicology | 34543702 | 2021 Nov |
milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues. | Tamargo, Manuel Alejandro; Nash, Trevor Ray; Fleischer, Sharon; Kim, Youngbin; Vila, Olaia Fernandez; Yeager, Keith; Summers, Max; Zhao, Yimu; Lock, Roberta; Chavez, Miguel; Costa, Troy; Vunjak-Novakovic, Gordana | ACS biomaterials science & engineering | 34668692 | 2021 11 08 |
Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency. | Laemmle, Alexander; Poms, Martin; Hsu, Bernadette; Borsuk, Mariia; Rüfenacht, Véronique; Robinson, Joshua; Sadowski, Martin C; Nuoffer, Jean-Marc; Häberle, Johannes; Willenbring, Holger | Hepatology (Baltimore, Md.) | 34786702 | 2021 Nov 16 |
Organ-on-a-chip model of vascularized human bone marrow niches. | Glaser, Drew E; Curtis, Matthew B; Sariano, Peter A; Rollins, Zachary A; Shergill, Bhupinder S; Anand, Aravind; Deely, Alyssa M; Shirure, Venktesh S; Anderson, Leif; Lowen, Jeremy M; Ng, Natalie R; Weilbaecher, Katherine; Link, Daniel C; George, Steven C | Biomaterials | 34810038 | 2022 01 |
Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. | Eicher, Alexandra K; Kechele, Daniel O; Sundaram, Nambirajan; Berns, H Matthew; Poling, Holly M; Haines, Lauren E; Sanchez, J Guillermo; Kishimoto, Keishi; Krishnamurthy, Mansa; Han, Lu; Zorn, Aaron M; Helmrath, Michael A; Wells, James M | Cell stem cell | 34856121 | 2022 01 06 |
Cyclosporine Induces Fenestra-Associated Injury in Human Renal Microvessels In Vitro. | Nagao, Ryan J; Marcu, Raluca; Shin, Yu Jung; Lih, Daniel; Xue, Jun; Arang, Nadia; Wei, Ling; Akilesh, Shreeram; Kaushansky, Alexis; Himmelfarb, Jonathan; Zheng, Ying | ACS biomaterials science & engineering | 34927415 | 2022 01 10 |
Network inference with Granger causality ensembles on single-cell transcriptomics. | Deshpande, Atul; Chu, Li-Fang; Stewart, Ron; Gitter, Anthony | Cell reports | 35139376 | 2022 02 08 |
An autonomously swimming biohybrid fish designed with human cardiac biophysics. | Lee, Keel Yong; Park, Sung-Jin; Matthews, David G; Kim, Sean L; Marquez, Carlos Antonio; Zimmerman, John F; Ardoña, Herdeline Ann M; Kleber, Andre G; Lauder, George V; Parker, Kevin Kit | Science (New York, N.Y.) | 35143298 | 2022 02 11 |
Endothelial Cell Differentiation and Hemogenic Specification. | Aragon, Jordon W; Hirschi, Karen K | Cold Spring Harbor perspectives in medicine | 35193895 | 2022 07 29 |
Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity. | Pamies, David; Wiersma, Daphne; Katt, Moriah E; Zhao, Liang; Burtscher, Johannes; Harris, Georgina; Smirnova, Lena; Searson, Peter C; Hartung, Thomas; Hogberg, Helena T | Neurobiology of disease | 35398340 | 2022 07 |
Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia. | Cruz, Nelly M; Reddy, Raghava; McFaline-Figueroa, José L; Tran, Christine; Fu, Hongxia; Freedman, Benjamin S | Nature biomedical engineering | 35478224 | 2022 04 |
Kidney microphysiological models for nephrotoxicity assessment. | Mahadeo, Anish; Yeung, Catherine K; Himmelfarb, Jonathan; Kelly, Edward J | Current opinion in toxicology | 35495549 | 2022 Jun |
Comparison of Bayesian vs Frequentist Adaptive Trial Design in the Stroke Hyperglycemia Insulin Network Effort Trial. | Broglio, Kristine; Meurer, William J; Durkalski, Valerie; Pauls, Qi; Connor, Jason; Berry, Donald; Lewis, Roger J; Johnston, Karen C; Barsan, William G | JAMA network open | 35544137 | 2022 05 02 |
A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models. | Singh, Dharaminder; Deosarkar, Sudhir P; Cadogan, Elaine; Flemington, Vikki; Bray, Alysha; Zhang, Jingwen; Reiserer, Ronald S; Schaffer, David K; Gerken, Gregory B; Britt, Clayton M; Werner, Erik M; Gibbons, Francis D; Kostrzewski, Tomasz; Chambers, Chris | PLoS biology | 35617197 | 2022 05 |
A vascularized model of the human liver mimics regenerative responses. | Chhabra, Arnav; Song, H-H Greco; Grzelak, Katarzyna A; Polacheck, William J; Fleming, Heather E; Chen, Christopher S; Bhatia, Sangeeta N | Proceedings of the National Academy of Sciences of the United States of America | 35763565 | 2022 Jul 12 |
Recreating the heart's helical structure-function relationship with focused rotary jet spinning. | Chang, Huibin; Liu, Qihan; Zimmerman, John F; Lee, Keel Yong; Jin, Qianru; Peters, Michael M; Rosnach, Michael; Choi, Suji; Kim, Sean L; Ardoña, Herdeline Ann M; MacQueen, Luke A; Chantre, Christophe O; Motta, Sarah E; Cordoves, Elizabeth M; Parker, Kevin | Science (New York, N.Y.) | 35857545 | 2022 07 08 |
Engineering Modular 3D Liver Culture Microenvironments In Vitro to Parse the Interplay between Biophysical and Biochemical Microenvironment Cues on Hepatic Phenotypes. | Wang, Alex J; Allen, Allysa; Sofman, Marianna; Sphabmixay, Pierre; Yildiz, Ece; Griffith, Linda G | Advanced nanobiomed research | 35872804 | 2022 Jan |
Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease. | Li, Sienna R; Gulieva, Ramila E; Helms, Louisa; Cruz, Nelly M; Vincent, Thomas; Fu, Hongxia; Himmelfarb, Jonathan; Freedman, Benjamin S | Nature communications | 36564419 | 2022 Dec 23 |
Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome. | Abutaleb, Nadia O; Atchison, Leigh; Choi, Leandro; Bedapudi, Akhil; Shores, Kevin; Gete, Yantenew; Cao, Kan; Truskey, George A | Scientific reports | 36977745 | 2023 Mar 28 |
Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone. | Genet, Nafiisha; Genet, Gael; Chavkin, Nicholas W; Paila, Umadevi; Fang, Jennifer S; Vasavada, Hema H; Goldberg, Joshua S; Acharya, Bipul R; Bhatt, Neha S; Baker, Kasey; McDonnell, Stephanie P; Huba, Mahalia; Sankaranarayanan, Danya; Ma, Gerry Z M; Eichmann, Anne; Thomas, Jean-Leon; Ffrench-Constant, Charles; Hirschi, Karen K | Cell reports | 37043357 | 2023 Apr 25 |
Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice. | Kam, Chen Yuan; Singh, Ishani D; Gonzalez, David G; Matte-Martone, Catherine; Solá, Paloma; Solanas, Guiomar; Bonjoch, Júlia; Marsh, Edward; Hirschi, Karen K; Greco, Valentina | Cell | 37167971 | 2023 May 25 |
MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis. | Wu, Yinyu; Paila, Umadevi; Genet, Gael; Hirschi, Karen K | Developmental cell | 37295435 | 2023 Jul 24 |
One transgene, two myopathies: an MTM1 'cross gene therapy' for BIN1 deficiency? | Asgarian, Zeinab; Siam, Ala'a; Counsell, John R | Brain : a journal of neurology | 37738144 | 2023 Oct 03 |
Emulator-based Bayesian inference on non-proportional scintillation models by compton-edge probing. | Breitenmoser, David; Cerutti, Francesco; Butterweck, Gernot; Kasprzak, Malgorzata Magdalena; Mayer, Sabine | Nature communications | 38012127 | 2023 Nov 28 |