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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Authors Journal PubMedID Publication Date
Transporters in drug-refractory epilepsy: clinical significance. Marchi, N; Gonzalez-Martinez, J; Nguyen, M-T; Granata, T; Janigro, D Clinical pharmacology and therapeutics 20019694 2010 Jan
Biophysics and dynamics of natural and engineered stem cell microenvironments. Keung, Albert J; Healy, Kevin E; Kumar, Sanjay; Schaffer, David V Wiley interdisciplinary reviews. Systems biology and medicine 20836010 2010 Jan-Feb
Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of *-catenin signaling. Cimetta, Elisa; Cannizzaro, Christopher; James, Richard; Biechele, Travis; Moon, Randall T; Elvassore, Nicola; Vunjak-Novakovic, Gordana Lab on a chip. 20936235 2010 Dec 7;
Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces. Pham, Christine T N; Mitchell, Lynne M; Huang, Jennifer L; Lubniewski, Christopher M; Schall, Otto F; Killgore, J Kendall; Pan, Dipanjan; Wickline, Samuel A; Lanza, Gregory M; Hourcade, Dennis E The Journal of biological chemistry 21047788 2011 Jan 7
Informatics and standards for nanomedicine technology. Thomas, Dennis G; Klaessig, Fred; Harper, Stacey L; Fritts, Martin; Hoover, Mark D; Gaheen, Sharon; Stokes, Todd H; Reznik-Zellen, Rebecca; Freund, Elaine T; Klemm, Juli D; Paik, David S; Baker, Nathan A Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 21721140 2011 Jun 30
Nanotherapeutic approaches for the treatment of rheumatoid arthritis. Pham, Christine T N Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 21837725 2011 Nov-Dec;
Manganese-based MRI contrast agents: past, present and future. Pan, Dipanjan; Schmieder, Anne H; Wickline, Samuel A; Lanza, Gregory M Tetrahedron. 22043109 2011 Nov 04;
Interaction of melittin peptides with perfluorocarbon nanoemulsion particles. Lee, Sun-Joo; Schlesinger, Paul H; Wickline, Samuel A; Lanza, Gregory M; Baker, Nathan A The journal of physical chemistry. B 22050303 2011 Dec 29
Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip. Grosberg, Anna; Alford, Patrick W; McCain, Megan L; Parker, Kevin Kit Lab on a chip 22072288 2011 Dec 21
An early investigation of ytterbium nanocolloids for selective and quantitative "multicolor" spectral CT imaging. Pan, Dipanjan; Schirra, Carsten O; Senpan, Angana; Schmieder, Anne H; Stacy, Allen J; Roessl, Ewald; Thran, Axel; Wickline, Samuel A; Proska, Roland; Lanza, Gregory M ACS nano 22385324 2012 Apr 24
An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project. Meurer, William J; Lewis, Roger J; Tagle, Danilo; Fetters, Michael D; Legocki, Laurie; Berry, Scott; Connor, Jason; Durkalski, Valerie; Elm, Jordan; Zhao, Wenle; Frederiksen, Shirley; Silbergleit, Robert; Palesch, Yuko; Berry, Donald A; Barsan, William G Annals of emergency medicine 22424650 2012 Oct
ICAM-1 and nanomedicine: nature's doorway to the extravascular tissue realm. Lanza, Gregory M Arteriosclerosis, thrombosis, and vascular biology 22517363 2012 May
Muscle on a chip: in vitro contractility assays for smooth and striated muscle. Grosberg, Anna; Nesmith, Alexander P; Goss, Josue A; Brigham, Mark D; McCain, Megan L; Parker, Kevin Kit Journal of pharmacological and toxicological methods 22521339 2012 May-Jun
Effect of insurance status on postacute care among working age stroke survivors. Skolarus, L E; Meurer, W J; Burke, J F; Prvu Bettger, J; Lisabeth, L D Neurology 22551730 2012 May 15
Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier. Janigro, Damir Epilepsia. 22612806 2012 Jun;
Adaptive clinical trials: a partial remedy for the therapeutic misconception? Meurer, William J; Lewis, Roger J; Berry, Donald A JAMA : the journal of the American Medical Association 22692168 2012 Jun 13
Antiangiogenic nanotherapy with lipase-labile Sn-2 fumagillin prodrug. Pan, Dipanjan; Sanyal, Nibedita; Schmieder, Anne H; Senpan, Angana; Kim, Benjamin; Yang, Xiaoxia; Hu, Grace; Allen, John S; Gross, Richard W; Wickline, Samuel A; Lanza, Gregory M Nanomedicine (London, England) 22709347 2012 Oct
Simulation of fusion-mediated nanoemulsion interactions with model lipid bilayers. Lee, Sun-Joo; Schlesinger, Paul H; Wickline, Samuel A; Lanza, Gregory M; Baker, Nathan A Soft matter 22712024 2012 Jan 1
The contribution of cellular mechanotransduction to cardiomyocyte form and function. Sheehy, Sean P; Grosberg, Anna; Parker, Kevin Kit Biomechanics and modeling in mechanobiology 22772714 2012 Nov
A mini-microscope for in situ monitoring of cells. Kim, Sang Bok; Koo, Kyo-in; Bae, Hojae; Dokmeci, Mehmet R; Hamilton, Geraldine A; Bahinski, Anthony; Kim, Sun Min; Ingber, Donald E; Khademhosseini, Ali Lab on a chip 22911426 2012 Oct 21
Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence. Hu, Lingzhi; Chen, Junjie; Yang, Xiaoxia; Caruthers, Shelton D; Lanza, Gregory M; Wickline, Samuel A Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 22915328 2012 Aug 22
Suppression of inflammation in a mouse model of rheumatoid arthritis using targeted lipase-labile fumagillin prodrug nanoparticles. Zhou, Hui-Fang; Yan, Huimin; Senpan, Angana; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T N Biomaterials 22922023 2012 Nov
Nanoinformatics: developing new computing applications for nanomedicine. Maojo, V; Fritts, M; Martin-Sanchez, F; De la Iglesia, D; Cachau, R E; Garcia-Remesal, M; Crespo, J; Mitchell, J A; Anguita, A; Baker, N; Barreiro, J M; Benitez, S E; De la Calle, G; Facelli, J C; Ghazal, P; Geissbuhler, A; Gonzalez-Nilo, F; Graf, N; Gran Computing in science & engineering 22942787 2012 Jun 1
Nanoinformatics: developing new computing applications for nanomedicine. Maojo, V; Fritts, M; Martin-Sanchez, F; De la Iglesia, D; Cachau, R E; Garcia-Remesal, M; Crespo, J; Mitchell, J A; Anguita, A; Baker, N; Barreiro, J M; Benitez, S E; De la Calle, G; Facelli, J C; Ghazal, P; Geissbuhler, A; Gonzalez-Nilo, F; Graf, N; Grangeat, P; Hermosilla, I; Hussein, R; Kern, J; Koch, S; Legre, Y; Lopez-Alonso, V; Lopez-Campos, G; Milanesi, L; Moustakis, V; Munteanu, C; Otero, P; Pazos, A; Perez-Rey, D; Potamias, G; Sanz, F; Kulikowski, C Computing in science & engineering 22942787 2012 Jun 1
Near infrared imaging of EGFR of oral squamous cell carcinoma in mice administered arsenic trioxide. Zhang, Lingbo; Wang, Kezheng; Zhao, Falin; Hu, Weiping; Chen, Junjie; Lanza, Gregory M; Shen, Baozhong; Zhang, Bin PloS one 23029451 2012
Angiogenesis is required for stress fracture healing in rats. Tomlinson, Ryan E; McKenzie, Jennifer A; Schmieder, Anne H; Wohl, Gregory R; Lanza, Gregory M; Silva, Matthew J Bone 23044046 2013 Jan
Bursting drops in solid dielectrics caused by high voltages. Wang, Qiming; Suo, Zhigang; Zhao, Xuanhe Nature communications. 23093194 2012;
Elucidation of adhesion-dependent spontaneous apoptosis in macrophages using phase separated PEG/polyurethane films. Zachman, Angela L; Page, Jonathan M; Prabhakar, Gayathri; Guelcher, Scott A; Sung, Hak-Joon Acta biomaterialia. 23128157 2013 Feb;
A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Huh, Dongeun; Leslie, Daniel C; Matthews, Benjamin D; Fraser, Jacob P; Jurek, Samuel; Hamilton, Geraldine A; Thorneloe, Kevin S; McAlexander, Michael Allen; Ingber, Donald E Science translational medicine 23136042 2012 Nov 7
Second Generation Gold Nanobeacons for Robust K-Edge Imaging with Multi-Energy CT. Schirra, Carsten O; Senpan, Angana; Roessl, Ewald; Thran, Axel; Stacy, Allen J; Wu, Lina; Proska, Roland; Pan, Dipanjan Journal of materials chemistry. 23185109 2012 Jan 01;
Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells. Cimetta, Elisa; Sirabella, Dario; Yeager, Keith; Davidson, Kathryn; Simon, Joseph; Moon, Randall T; Vunjak-Novakovic, Gordana Lab on a chip 23232509 2013 Feb 7
The inexorable rise of AKI: can we bend the growth curve? Siew, Edward D; Himmelfarb, Jonathan Journal of the American Society of Nephrology : JASN. 23243210 2013 Jan;
ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format. Thomas, Dennis G; Gaheen, Sharon; Harper, Stacey L; Fritts, Martin; Klaessig, Fred; Hahn-Dantona, Elizabeth; Paik, David; Pan, Sue; Stafford, Grace A; Freund, Elaine T; Klemm, Juli D; Baker, Nathan A BMC biotechnology 23311978 2013
Regenerative medicine in 2012: the coming of age of musculoskeletal tissue engineering. Tuan, Rocky S Nature reviews. Rheumatology. 23321611 2013 Feb;
Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis. Campanholle, Gabriela; Ligresti, Giovanni; Gharib, Sina A; Duffield, Jeremy S American journal of physiology. Cell physiology. 23325411 2013 Apr 1;
Modeling boundary conditions for balanced proliferation in metastatic latency. Taylor, Donald P; Wells, Jakob Z; Savol, Andrej; Chennubhotla, Chakra; Wells, Alan Clinical cancer research : an official journal of the American Association for Cancer Research 23329811 2013 Mar 1
Multifunctionality and control of the crumpling and unfolding of large-area graphene. Zang, Jianfeng; Ryu, Seunghwa; Pugno, Nicola; Wang, Qiming; Tu, Qing; Buehler, Markus J; Zhao, Xuanhe Nature materials. 23334002 2013 Apr;
Nonsteady state oxygen transport in engineered tissue: implications for design. Ehsan, Seema M; George, Steven C Tissue engineering. Part A. 23350630 2013 Jun;
Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes. Robertson, Claire; Tran, David D; George, Steven C Stem cells (Dayton, Ohio). 23355363 2013 May;
Engineering challenges for instrumenting and controlling integrated organ-on-chip systems. Wikswo, John P; Block 3rd, Frank E; Cliffel, David E; Goodwin, Cody R; Marasco, Christina C; Markov, Dmitry A; McLean, David L; McLean, John A; McKenzie, Jennifer R; Reiserer, Ronald S; Samson, Philip C; Schaffer, David K; Seale, Kevin T; Sherrod, Stacy D IEEE transactions on bio-medical engineering 23380852 2013 Mar
Standardizing data. Baker, Nathan A; Klemm, Juli D; Harper, Stacey L; Gaheen, Sharon; Heiskanen, Mervi; Rocca-Serra, Philippe; Sansone, Susanna-Assunta Nature nanotechnology 23380926 2013 Feb
A new dynamic in vitro modular capillaries-venules modular system: cerebrovascular physiology in a box. Cucullo, Luca; Hossain, Mohammed; Tierney, William; Janigro, Damir BMC neuroscience. 23388041 2013;
Does Systemic Inflammation Play a Role in Pediatric Psychosis? Falcone, Tatiana; Carlton, Erin; Lee, Catherine; Janigro, Mattia; Fazio, Vince; Forcen, Fernando Espi; Franco, Kathleen; Janigro, Damir Clinical schizophrenia & related psychoses 23491967 2015
EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury. Kida, Yujiro; Ieronimakis, Nicholas; Schrimpf, Claudia; Reyes, Morayma; Duffield, Jeremy S Journal of the American Society of Nephrology : JASN. 23492730 2013 Mar;
Poly(?-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells. Crowder, Spencer W; Liang, Yi; Rath, Rutwik; Park, Andrew M; Maltais, Simon; Pintauro, Peter N; Hofmeister, William; Lim, Chee C; Wang, Xintong; Sung, Hak-Joon Nanomedicine (London, England). 23530764 2013 Nov;
Bioreactor engineering of stem cell environments. Tandon, Nina; Marolt, Darja; Cimetta, Elisa; Vunjak-Novakovic, Gordana Biotechnology advances 23531529 2013 Mar 24
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro. Nguyen, Duc-Huy T; Stapleton, Sarah C; Yang, Michael T; Cha, Susie S; Choi, Colin K; Galie, Peter A; Chen, Christopher S Proceedings of the National Academy of Sciences of the United States of America. 23569284 2013 Apr 23;
A therapy for liver failure found in the JNK yard. Willenbring, Holger; Grompe, Markus Cell. 23582318 2013 Apr 11;
Three-dimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells. Crowder, Spencer W; Prasai, Dhiraj; Rath, Rutwik; Balikov, Daniel A; Bae, Hojae; Bolotin, Kirill I; Sung, Hak-Joon Nanoscale. 23592029 2013 May 21;
Production and assessment of decellularized pig and human lung scaffolds. Nichols, Joan E; Niles, Jean; Riddle, Michael; Vargas, Gracie; Schilagard, Tuya; Ma, Liang; Edward, Kert; La Francesca, Saverio; Sakamoto, Jason; Vega, Stephanie; Ogadegbe, Marie; Mlcak, Ronald; Deyo, Donald; Woodson, Lee; McQuitty, Christopher; Lick, Sco Tissue engineering. Part A. 23638920 2013 Sep;
Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. Zhang, Donghui; Shadrin, Ilya Y; Lam, Jason; Xian, Hai-Qian; Snodgrass, H Ralph; Bursac, Nenad Biomaterials. 23642535 2013 Jul;
Mechanistic validation. Hartung, Thomas; Hoffmann, Sebastian; Stephens, Martin ALTEX 23665802 2013
Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. Ma, Xiaocui; Duan, Yuyou; Tschudy-Seney, Benjamin; Roll, Garrett; Behbahan, Iman Saramipoor; Ahuja, Tijess P; Tolstikov, Vladimir; Wang, Charles; McGee, Jeannine; Khoobyari, Shiva; Nolta, Jan A; Willenbring, Holger; Zern, Mark A Stem cells translational medicine. 23681950 2013 Jun;
Engineering skeletal muscle repair. Juhas, Mark; Bursac, Nenad Current opinion in biotechnology. 23711735 2013 Oct;
Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip. McCain, Megan L; Sheehy, Sean P; Grosberg, Anna; Goss, Josue A; Parker, Kevin Kit Proceedings of the National Academy of Sciences of the United States of America. 23716679 2013 Jun 11;
Pericytes in kidney fibrosis. Ren, Shuyu; Duffield, Jeremy S Current opinion in nephrology and hypertension. 23722183 2013 Jul;
A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays. Hsu, Yu-Hsiang; Moya, Monica L; Hughes, Christopher C W; George, Steven C; Lee, Abraham P Lab on a chip. 23723013 2013 Aug 7;
Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts. Shi, Mingjian; Majumdar, Devi; Gao, Yandong; Brewer, Bryson M; Goodwin, Cody R; McLean, John A; Li, Deyu; Webb, Donna J Lab on a chip. 23736663 2013 Aug 7;
Changes in macrophage phenotype as the immune response evolves. Lichtnekert, Julia; Kawakami, Takahisa; Parks, William C; Duffield, Jeremy S Current opinion in pharmacology. 23747023 2013 Aug;
Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. Christoforou, Nicolas; Liau, Brian; Chakraborty, Syandan; Chellapan, Malathi; Bursac, Nenad; Leong, Kam W PloS one. 23785459 2013;
Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients. Baker, Brendon M; Trappmann, Britta; Stapleton, Sarah C; Toro, Esteban; Chen, Christopher S Lab on a chip. 23787488 2013 Aug 21;
The Dormancy Dilemma: Quiescence versus Balanced Proliferation. Wells, Alan; Griffith, Linda; Wells, Jakob Z; Taylor, Donald P Cancer research 23794703 2013 Jun 21
Microfluidic heart on a chip for higher throughput pharmacological studies. Agarwal, Ashutosh; Goss, Josue Adrian; Cho, Alexander; McCain, Megan Laura; Parker, Kevin Kit Lab on a chip 23807141 2013 Aug 13
Scaling and systems biology for integrating multiple organs-on-a-chip. Wikswo, John P; Curtis, Erica L; Eagleton, Zachary E; Evans, Brian C; Kole, Ayeeshik; Hofmeister, Lucas H; Matloff, William J Lab on a chip 23828456 2013 Aug 13
Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus. Connor, Jason T; Elm, Jordan J; Broglio, Kristine R; ESETT and ADAPT-IT Investigators Journal of clinical epidemiology 23849147 2013 Aug
Spinal Cord Injury Neuroprotection and the Promise of Flexible Adaptive Clinical Trials. Meurer, William J; Barsan, William G World neurosurgery 23851207 2013 Jul 9
Look back in anger - what clinical studies tell us about preclinical work. Hartung, Thomas ALTEX 23861075 2013
Expression and functional relevance of UGT1A4 in a cohort of human drug-resistant epileptic brains. Ghosh, Chaitali; Hossain, Mohammed; Puvenna, Vikram; Martinez-Gonzalez, Jorge; Alexopolous, Andreas; Janigro, Damir; Marchi, Nicola Epilepsia. 23865846 2013 Sep;
Rat hepatocyte culture model of macrosteatosis: effect of macrosteatosis induction and reversal on viability and liver-specific function. Nativ, Nir I; Yarmush, Gabriel; Chen, Alvin; Dong, David; Henry, Scot D; Guarrera, James V; Klein, Kenneth M; Maguire, Tim; Schloss, Rene; Berthiaume, Francois; Yarmush, Martin L Journal of hepatology. 23872604 2013 Dec;
Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. Johnston, S Claiborne; Easton, J Donald; Farrant, Mary; Barsan, William; Battenhouse, Holly; Conwit, Robin; Dillon, Catherine; Elm, Jordan; Lindblad, Anne; Morgenstern, Lewis; Poisson, Sharon N; Palesch, Yuko International journal of stroke : official journal of the International Stroke Society 23879752 2013 Aug
Transplantable liver organoids made from only three ingredients. Willenbring, Holger; Soto-Gutierrez, Alejandro Cell stem cell. 23910079 2013 Aug 1;
Characterization of early neovascular response to acute lung ischemia using simultaneous (19)F/ (1)H MR molecular imaging. Schmieder, Anne H; Wang, Kezheng; Zhang, Huiying; Senpan, Angana; Pan, Dipanjan; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Shen, Baozhong; Wagner, Elizabeth M; Lanza, Gregory M Angiogenesis 23918207 2014 Jan
Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. Hung, Chi; Linn, Geoffrey; Chow, Yu-Hua; Kobayashi, Akio; Mittelsteadt, Kristen; Altemeier, William A; Gharib, Sina A; Schnapp, Lynn M; Duffield, Jeremy S American journal of respiratory and critical care medicine 23924232 2013 Oct 01
A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells. Magness, Scott T; Puthoff, Brent J; Crissey, Mary Ann; Dunn, James; Henning, Susan J; Houchen, Courtney; Kaddis, John S; Kuo, Calvin J; Li, Linheng; Lynch, John; Martin, Martin G; May, Randal; Niland, Joyce C; Olack, Barbara; Qian, Dajun; Stelzner, Matthi American journal of physiology. Gastrointestinal and liver physiology. 23928185 2013 Oct 15;
Bioengineering heart tissue for in vitro testing. Cimetta, Elisa; Godier-Furnemont, Amandine; Vunjak-Novakovic, Gordana Current opinion in biotechnology 23932513 2013 Aug 6
Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase. Coulter, Jonathan B; O'Driscoll, Cliona M; Bressler, Joseph P The Journal of biological chemistry. 23940045 2013 Oct 4;
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Hou, Zhonggang; Zhang, Yan; Propson, Nicholas E; Howden, Sara E; Chu, Li-Fang; Sontheimer, Erik J; Thomson, James A Proceedings of the National Academy of Sciences of the United States of America. 23940360 2013 Sep 24;
Clear castable polyurethane elastomer for fabrication of microfluidic devices. Domansky, Karel; Leslie, Daniel C; McKinney, James; Fraser, Jacob P; Sliz, Josiah D; Hamkins-Indik, Tiama; Hamilton, Geraldine A; Bahinski, Anthony; Ingber, Donald E Lab on a chip 23954953 2013 Oct 7
Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions. Kawakami, Takahisa; Lichtnekert, Julia; Thompson, Lucas J; Karna, Prasanthi; Bouabe, Hicham; Hohl, Tobias M; Heinecke, Jay W; Ziegler, Steven F; Nelson, Peter J; Duffield, Jeremy S Journal of immunology (Baltimore, Md. : 1950) 23956422 2013 Sep 15
A brief account of nanoparticle contrast agents for photoacoustic imaging. Pan, Dipanjan; Kim, Benjamin; Wang, Lihong V; Lanza, Gregory M Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 23983210 2013 Nov-Dec
A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches. Janigro, Damir; Iffland 2nd, Philip H; Marchi, Nicola; Granata, Tiziana Epilepsia. 24001067 2013 Sep;
The established status epilepticus trial 2013. Bleck, Thomas; Cock, Hannah; Chamberlain, James; Cloyd, James; Connor, Jason; Elm, Jordan; Fountain, Nathan; Jones, Elizabeth; Lowenstein, Daniel; Shinnar, Shlomo; Silbergleit, Robert; Treiman, David; Trinka, Eugen; Kapur, Jaideep Epilepsia 24001084 2013 Sep
Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix. Yang, Guang; Rothrauff, Benjamin B; Lin, Hang; Gottardi, Riccardo; Alexander, Peter G; Tuan, Rocky S Biomaterials. 24044998 2013 Dec;
Variation in diffusion of gases through PDMS due to plasma surface treatment and storage conditions. Markov, Dmitry A; Lillie, Elizabeth M; Garbett, Shawn P; McCawley, Lisa J Biomedical microdevices. 24065585 2014 Feb;
Femtosecond laser-patterned nanopore arrays for surface-mediated peptide treatment. Zachman, Angela L; Hofmeister, Lucas H; Costa, Lino; Boire, Timothy C; Hwang, Yu-Shik; Hofmeister, William H; Sung, Hak-Joon Nanomedicine : nanotechnology, biology, and medicine 24090768 2014 Jan
Portable bioreactor for perfusion and electrical stimulation of engineered cardiac tissue. Tandon, Nina; Taubman, Alanna; Cimetta, Elisa; Saccenti, Laetitia; Vunjak-Novakovic, Gordana Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 24111161 2013;
Microfabrication of human organs-on-chips. Huh, Dongeun; Kim, Hyun Jung; Fraser, Jacob P; Shea, Daniel E; Khan, Mohammed; Bahinski, Anthony; Hamilton, Geraldine A; Ingber, Donald E Nature protocols 24113786 2013 Nov
Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport. Yeung, Catherine K; Shen, Danny D; Thummel, Kenneth E; Himmelfarb, Jonathan Kidney international 24132209 2014 Mar
Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers. Fernandez, Cristina E; Obi-onuoha, Izundu C; Wallace, Charles S; Satterwhite, Lisa L; Truskey, George A; Reichert, William M Acta biomaterialia 24140604 2014 Feb
Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs). Itoh, Munenari; Umegaki-Arao, Noriko; Guo, Zongyou; Liu, Liang; Higgins, Claire A; Christiano, Angela M PloS one. 24147053 2013;
Microfluidic device to culture 3D in vitro human capillary networks. Moya, Monica L; Alonzo, Luis F; George, Steven C Methods in molecular biology (Clifton, N.J.). 24155229 2014;
Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption. Singh, Varsha; Yang, Jianbo; Chen, Tiane-e; Zachos, Nicholas C; Kovbasnjuk, Olga; Verkman, Alan S; Donowitz, Mark Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 24184676 2014 Jan;
Development of a new method for the isolation and culture of pulmonary arterial endothelial cells from rat pulmonary arteries. Peng, Gongyong; Wen, Xing; Shi, Yu; Jiang, Yongliang; Hu, Guoping; Zhou, Yumin; Ran, Pixin Journal of vascular research. 24192526 2013;
Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles. Pham, Christine T N; Thomas, Dennis G; Beiser, Julia; Mitchell, Lynne M; Huang, Jennifer L; Senpan, Angana; Hu, Grace; Gordon, Mae; Baker, Nathan A; Pan, Dipanjan; Lanza, Gregory M; Hourcade, Dennis E Nanomedicine : nanotechnology, biology, and medicine 24211337 2013 Nov 8
New immunological approaches in treating and diagnosing CNS diseases. Guo, Kathy; Janigro, Damir Pharmaceutical patent analyst 24237062 2013 May
Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion. Grahovac, Jelena; Wells, Alan Laboratory investigation; a journal of technical methods and pathology 24247562 2014 Jan
Three-dimensional filamentous human diseased cardiac tissue model. Ma, Zhen; Koo, Sangmo; Finnegan, Micaela A; Loskill, Peter; Huebsch, Nathaniel; Marks, Natalie C; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin E Biomaterials 24268663 2014 Feb
Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems. Hong, Sungmin; Jung, Youngmee; Yen, Ringo; Chan, Hon Fai; Leong, Kam W; Truskey, George A; Zhao, Xuanhe Lab on a chip. 24310854 2014 Feb 7;
Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients. McLaughlin, Bethann; Gidday, Jeff M Translational stroke research 24323191 2013 Feb
Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays. Nguyen, Eric H; Zanotelli, Matthew R; Schwartz, Michael P; Murphy, William L Biomaterials 24332391 2014 Feb
Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. Cheng, Cindy S; El-Abd, Yasser; Bui, Khanh; Hyun, Young-Eun; Hughes, Rebecca Harbuck; Kraus, William E; Truskey, George A American journal of physiology. Cell physiology 24336652 2014 Feb 15
Harnessing localized ridges for high-aspect-ratio hierarchical patterns with dynamic tunability and multifunctionality. Cao, Changyong; Chan, Hon Fai; Zang, Jianfeng; Leong, Kam W; Zhao, Xuanhe Advanced materials (Deerfield Beach, Fla.) 24339233 2014 Mar 19
Assessing the barriers to image-guided drug delivery. Lanza, Gregory M; Moonen, Chrit; Baker Jr, James R; Chang, Esther; Cheng, Zheng; Grodzinski, Piotr; Ferrara, Katherine; Hynynen, Kullervo; Kelloff, Gary; Lee, Yong-Eun Koo; Patri, Anil K; Sept, David; Schnitzer, Jan E; Wood, Bradford J; Zhang, Miqin; Zhen Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 24339356 2014 Jan-Feb
Inflammatory pathways of seizure disorders. Marchi, Nicola; Granata, Tiziana; Janigro, Damir Trends in neurosciences. 24355813 2014 Feb;
Physiologically relevant organs on chips. Yum, Kyungsuk; Hong, Soon Gweon; Healy, Kevin E; Lee, Luke P Biotechnology journal. 24357624 2014 Jan;
Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles. Rangarajan, Swathi; Madden, Lauran; Bursac, Nenad Annals of biomedical engineering. 24366526 2014 Jul;
Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy. Li, Fengqiang; Xu, Ting; Nguyen, Duc-Huy T; Huang, Xiaolei; Chen, Christopher S; Zhou, Chao Journal of biomedical optics. 24395588 2014 Jan;
How multi-organ microdevices can help foster drug development. Esch, Mandy B; Smith, Alec S T; Prot, Jean-Matthieu; Oleaga, Carlota; Hickman, James J; Shuler, Michael L Advanced drug delivery reviews. 24412641 2014 Apr;
The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine. Martins, Ana M; Vunjak-Novakovic, Gordana; Reis, Rui L Stem cell reviews 24425421 2014 Apr
Mapping the human toxome by systems toxicology. Bouhifd, Mounir; Hogberg, Helena T; Kleensang, Andre; Maertens, Alexandra; Zhao, Liang; Hartung, Thomas Basic & clinical pharmacology & toxicology 24443875 2014 Jul
Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer. May, Jody C; Goodwin, Cody R; Lareau, Nichole M; Leaptrot, Katrina L; Morris, Caleb B; Kurulugama, Ruwan T; Mordehai, Alex; Klein, Christian; Barry, William; Darland, Ed; Overney, Gregor; Imatani, Kenneth; Stafford, George C; Fjeldsted, John C; McLean, Jo Analytical chemistry. 24446877 2014 Feb 18;
Nanoinformatics workshop report: Current resources, community needs, and the proposal of a collaborative framework for data sharing and information integration. Harper, Stacey L; Hutchison, James E; Baker, Nathan; Ostraat, Michele; Tinkle, Sally; Steevens, Jeffrey; Hoover, Mark D; Adamick, Jessica; Rajan, Krishna; Gaheen, Sharon; Cohen, Yoram; Nel, Andre; Cachau, Raul E; Tuominen, Mark Computational science & discovery 24454543 2013
Molecular imaging with computed tomography. Lanza, Gregory M; Pan, Dipanjan Contrast media & molecular imaging 24470289 2014 Jan-Feb
Multicolor computed tomographic molecular imaging with noncrystalline high-metal-density nanobeacons. Pan, Dipanjan; Schirra, Carsten O; Wickline, Samuel A; Lanza, Gregory M Contrast media & molecular imaging 24470291 2014 Jan-Feb
Physical influences on stem cells. Vunjak-Novakovic, Gordana Stem cell research & therapy. 24476419 2013;
Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues. Li, Cheri Yingjie; Stevens, Kelly R; Schwartz, Robert E; Alejandro, Brian Steven; Huang, Joanne H; Bhatia, Sangeeta N Tissue engineering. Part A 24498910 2014 Feb 5
Biological and engineering design considerations for vascular tissue engineered blood vessels (TEBVs). Fernandez, Cristina E; Achneck, Hardean E; Reichert, William M; Truskey, George A Current opinion in chemical engineering. 24511460 2014 Feb 1;
Annotating the structure and components of a nanoparticle formulation using computable string expressions. Thomas, Dennis G; Chikkagoudar, Satish; Chappell, Alan R; Baker, Nathan A Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 24533226 2012 Dec 31;
Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system. Kelly, Edward J; Wang, Zhican; Voellinger, Jenna L; Yeung, Cathy K; Shen, Danny D; Thummel, Kenneth E; Zheng, Ying; Ligresti, Giovanni; Eaton, David L; Muczynski, Kimberly A; Duffield, Jeremy S; Neumann, Thomas; Tourovskaia, Anna; Fauver, Mark; Kramer, Gr Stem cell research & therapy. 24564863 2013;
Neurovascular unit on a chip: implications for translational applications. Alcendor, Donald J; Block 3rd, Frank E; Cliffel, David E; Daniels, John Scott; Ellacott, Kate L J; Goodwin, Cody R; Hofmeister, Lucas H; Li, Deyu; Markov, Dmitry A; May, Jody C; McCawley, Lisa J; McLaughlin, BethAnn; McLean, John A; Niswender, Kevin D; Pe Stem cell research & therapy. 24564885 2013;
Building a microphysiological skin model from induced pluripotent stem cells. Guo, Zongyou; Higgins, Claire A; Gillette, Brian M; Itoh, Munenari; Umegaki, Noriko; Gledhill, Karl; Sia, Samuel K; Christiano, Angela M Stem cell research & therapy. 24564920 2013;
Human enteroids: preclinical models of non-inflammatory diarrhea. Kovbasnjuk, Olga; Zachos, Nicholas C; In, Julie; Foulke-Abel, Jennifer; Ettayebi, Khalil; Hyser, Joseph M; Broughman, James R; Zeng, Xi-Lei; Middendorp, Sabine; de Jonge, Hugo R; Estes, Mary K; Donowitz, Mark Stem cell research & therapy. 24564938 2013;
Toward a 3D model of human brain development for studying gene/environment interactions. Hogberg, Helena T; Bressler, Joseph; Christian, Kimberly M; Harris, Georgina; Makri, Georgia; O'Driscoll, Cliona; Pamies, David; Smirnova, Lena; Wen, Zhexing; Hartung, Thomas Stem cell research & therapy. 24564953 2013;
Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. Hartman, Kira G; Bortner, James D; Falk, Gary W; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John P Stem cell research & therapy. 24564965 2013;
Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis. Lozito, Thomas P; Alexander, Peter G; Lin, Hang; Gottardi, Riccardo; Cheng, Anthony Wai-Ming; Tuan, Rocky S Stem cell research & therapy. 24564995 2013;
Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology. Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Cortiella, Joaquin Stem cell research & therapy. 24565038 2013;
HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease. Vunjak-Novakovic, Gordana; Bhatia, Sangeeta; Chen, Christopher; Hirschi, Karen Stem cell research & therapy 24565063 2013
Microphysiological systems and low-cost microfluidic platform with analytics. Smith, Alec S T; Long, Christopher J; Berry, Bonnie J; McAleer, Christopher; Stancescu, Maria; Molnar, Peter; Miller, Paula G; Esch, Mandy B; Prot, Jean-Matthieu; Hickman, James J; Shuler, Michael L Stem cell research & therapy. 24565109 2013;
Building additional complexity to in vitro-derived intestinal tissues. Brugmann, Samantha A; Wells, James M Stem cell research & therapy. 24565179 2013;
Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing. Truskey, George A; Achneck, Hardean E; Bursac, Nenad; Chan, Hon; Cheng, Cindy S; Fernandez, Cristina; Hong, Sungmin; Jung, Youngmee; Koves, Tim; Kraus, William E; Leong, Kam; Madden, Lauran; Reichert, William M; Zhao, Xuanhe Stem cell research & therapy. 24565225 2013;
All-human microphysical model of metastasis therapy. Wheeler, Sarah E; Borenstein, Jeffrey T; Clark, Amanda M; Ebrahimkhani, Mohammad R; Fox, Ira J; Griffith, Linda; Inman, Walker; Lauffenburger, Douglas; Nguyen, Transon; Pillai, Venkateswaran C; Prantil-Baun, Rachelle; Stolz, Donna B; Taylor, Donald; Ulric Stem cell research & therapy. 24565274 2013;
A human pluripotent stem cell platform for assessing developmental neural toxicity screening. Hou, Zhonggang; Zhang, Jue; Schwartz, Michael P; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James A Stem cell research & therapy. 24565336 2013;
Recreating the female reproductive tract in vitro using iPSC technology in a linked microfluidics environment. Laronda, Monica M; Burdette, Joanna E; Kim, J; Woodruff, Teresa K Stem cell research & therapy 24565375 2013
Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development. Mathur, Anurag; Loskill, Peter; Hong, Soongweon; Lee, Jae; Marcus, Sivan G; Dumont, Laure; Conklin, Bruce R; Willenbring, Holger; Lee, Luke P; Healy, Kevin E Stem cell research & therapy. 24565415 2013;
An integrated in vitro model of perfused tumor and cardiac tissue. Moya, Monica; Tran, David; George, Steven C Stem cell research & therapy. 24565445 2013;
Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans. Bhushan, Abhinav; Senutovitch, Nina; Bale, Shyam S; McCarty, William J; Hegde, Manjunath; Jindal, Rohit; Golberg, Inna; Berk Usta, O; Yarmush, Martin L; Vernetti, Lawrence; Gough, Albert; Bakan, Ahmet; Shun, Tong Ying; DeBiasio, Richard; Lansing Taylor, D Stem cell research & therapy. 24565476 2013;
Mouse liver repopulation with hepatocytes generated from human fibroblasts. Zhu, Saiyong; Rezvani, Milad; Harbell, Jack; Mattis, Aras N; Wolfe, Alan R; Benet, Leslie Z; Willenbring, Holger; Ding, Sheng Nature. 24572354 2014 Apr 3;
Three-dimensional paper-based model for cardiac ischemia. Mosadegh, Bobak; Dabiri, Borna E; Lockett, Matthew R; Derda, Ratmir; Campbell, Patrick; Parker, Kevin Kit; Whitesides, George M Advanced healthcare materials. 24574054 2014 Jul;
Cartilage tissue engineering application of injectable gelatin hydrogel with in situ visible-light-activated gelation capability in both air and aqueous solution. Lin, Hang; Cheng, Anthony Wai-Ming; Alexander, Peter G; Beck, Angela M; Tuan, Rocky S Tissue engineering. Part A. 24575844 2014 Sep;
Cancer Stem Cells under Hypoxia as a Chemoresistance Factor in Breast and Brain. Crowder, Spencer W; Balikov, Daniel A; Hwang, Yu-Shik; Sung, Hak-Joon Current pathobiology reports. 24587979 2014 Mar;
Myocardial tissue engineering: in vitro models. Vunjak Novakovic, Gordana; Eschenhagen, Thomas; Mummery, Christine Cold Spring Harbor perspectives in medicine. 24591534 2014 Mar;
Bioreactor technologies to support liver function in vitro. Ebrahimkhani, Mohammad R; Neiman, Jaclyn A Shepard; Raredon, Micha Sam B; Hughes, David J; Griffith, Linda G Advanced drug delivery reviews 24607703 2014 Apr
Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition. Taylor, Donald P; Clark, Amanda; Wheeler, Sarah; Wells, Alan Breast cancer research and treatment 24610032 2014 Apr
The mitogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase (ERK) are involved in hepatocyte-mediated phenotypic switching in prostate cancer cells. Ma, Bo; Wells, Alan The Journal of biological chemistry. 24619413 2014 Apr 18;
Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor. Diederichs, Solvig; Tuan, Rocky S Stem cells and development. 24625206 2014 Jul 15;
Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening. Zhao, Ruogang; Chen, Christopher S; Reich, Daniel H Biomaterials. 24630092 2014 Jun;
Antagonizing the *v *3 integrin inhibits angiogenesis and impairs woven but not lamellar bone formation induced by mechanical loading. Tomlinson, Ryan E; Schmieder, Anne H; Quirk, James D; Lanza, Gregory M; Silva, Matthew J Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 24644077 2014 Sep;
Engineering Liver. Griffith, Linda G; Wells, Alan; Stolz, Donna Beer Hepatology (Baltimore, Md.) 24668880 2014 Mar 26
Quality metrics for stem cell-derived cardiac myocytes. Sheehy, Sean P; Pasqualini, Francesco; Grosberg, Anna; Park, Sung Jin; Aratyn-Schaus, Yvonne; Parker, Kevin Kit Stem cell reports. 24672752 2014 Mar 11;
Structural characterization of methylenedianiline regioisomers by ion mobility-mass spectrometry, tandem mass spectrometry, and computational strategies: I. Electrospray spectra of 2-ring isomers. Forsythe, Jay G; Stow, Sarah M; Nefzger, Hartmut; Kwiecien, Nicholas W; May, Jody C; McLean, John A; Hercules, David M Analytical chemistry. 24678803 2014 May 6;
Matrix elasticity regulates the optimal cardiac myocyte shape for contractility. McCain, Megan L; Yuan, Hongyan; Pasqualini, Francesco S; Campbell, Patrick H; Parker, Kevin Kit American journal of physiology. Heart and circulatory physiology. 24682394 2014 Jun 1;
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities. Smirnova, Lena; Hogberg, Helena T; Leist, Marcel; Hartung, Thomas ALTEX 24687333 2014
The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. Kulangara, Karina; Adler, Andrew F; Wang, Hong; Chellappan, Malathi; Hammett, Ellen; Yasuda, Ryohei; Leong, Kam W Biomaterials. 24709523 2014 Jul;
Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract. Foulke-Abel, Jennifer; In, Julie; Kovbasnjuk, Olga; Zachos, Nicholas C; Ettayebi, Khalil; Blutt, Sarah E; Hyser, Joseph M; Zeng, Xi-Lei; Crawford, Sue E; Broughman, James R; Estes, Mary K; Donowitz, Mark Experimental biology and medicine (Maywood, N.J.). 24719375 2014 Sep;
3D - a new dimension of in vitro research. Hartung, Thomas Advanced drug delivery reviews. 24721291 2014 Apr;
Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using *(v)*ýýý-targeted theranostic nanoparticles. Pan, Dipanjan; Schmieder, Anne H; Wang, Kezheng; Yang, Xiaoxia; Senpan, Angana; Cui, Grace; Killgore, Kendall; Kim, Benjamin; Allen, John S; Zhang, Huiying; Caruthers, Shelton D; Shen, Baozhong; Wickline, Samuel A; Lanza, Gregory M Theranostics 24723979 2014
Integrating in vitro organ-specific function with the microcirculation. Moya, Monica L; George, Steven C Current opinion in chemical engineering. 24729953 2014 Feb 1;
Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues. McCain, Megan L; Agarwal, Ashutosh; Nesmith, Haley W; Nesmith, Alexander P; Parker, Kevin Kit Biomaterials. 24731714 2014 Jul;
Microscale technologies for regulating human stem cell differentiation. Cimetta, Elisa; Vunjak-Novakovic, Gordana Experimental biology and medicine (Maywood, N.J.). 24737735 2014 Sep;
Microphysiological modeling of the reproductive tract: A fertile endeavor. Eddie, Sharon L; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna E Experimental biology and medicine (Maywood, N.J.) 24737736 2014 Apr 15
A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening. Heylman, Christopher; Sobrino, Agua; Shirure, Venktesh S; Hughes, Christopher Cw; George, Steven C Experimental biology and medicine (Maywood, N.J.). 24740872 2014 Sep;
Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKC? signaling. Cha, Boyoung; Chen, Tiane; Sarker, Rafiquel; Yang, Jianbo; Raben, Daniel; Tse, C Ming; Kovbasnjuk, Olga; Donowitz, Mark American journal of physiology. Cell physiology. 24760985 2014 Jul 1;
A three-dimensional in vitro model of tumor cell intravasation. Ehsan, Seema M; Welch-Reardon, Katrina M; Waterman, Marian L; Hughes, Christopher C W; George, Steven C Integrative biology : quantitative biosciences from nano to macro. 24763498 2014 Jun;
In vitro platforms for evaluating liver toxicity. Bale, Shyam Sundhar; Vernetti, Lawrence; Senutovitch, Nina; Jindal, Rohit; Hegde, Manjunath; Gough, Albert; McCarty, William J; Bakan, Ahmet; Bhushan, Abhinav; Shun, Tong Y; Golberg, Inna; DeBiasio, Richard; Usta, O Berk; Taylor, D Lansing; Yarmush, Marti Experimental biology and medicine (Maywood, N.J.). 24764241 2014 Sep;
Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research. Abrams, Julian A; Appelman, Henry D; Beer, David G; Berry, Lynne D; Chak, Amitabh; Falk, Gary W; Fitzgerald, Rebecca C; Ginsberg, Gregory G; Grady, William M; Joshi, Bishnu P; Lynch, John P; Markowitz, Sanford; Richmond, Ellen S; Rustgi, Anil K; Seibel, E Gastroenterology. 24768332 2014 Jun;
Dynamic interplay of flow and collagen stabilizes primary hepatocytes culture in a microfluidic platform. Hegde, Manjunath; Jindal, Rohit; Bhushan, Abhinav; Bale, Shyam Sundhar; McCarty, William J; Golberg, Inna; Usta, O Berk; Yarmush, Martin L Lab on a chip. 24770663 2014 Jun 21;
Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems. Hartman, Kira G; Bortner Jr, James D; Falk, Gary W; Ginsberg, Gregory G; Jhala, Nirag; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John P Experimental biology and medicine (Maywood, N.J.). 24781339 2014 Sep;
Approaches to in vitro tissue regeneration with application for human disease modeling and drug development. Ebrahimkhani, Mohammad R; Young, Carissa L; Lauffenburger, Douglas A; Griffith, Linda G; Borenstein, Jeffrey T Drug discovery today 24793141 2014 Jun
Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits. Puvenna, Vikram; Brennan, Chanda; Shaw, Gerald; Yang, Cui; Marchi, Nicola; Bazarian, Jeffrey J; Merchant-Borna, Kian; Janigro, Damir PloS one. 24806476 2014;
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. Wang, Gang; McCain, Megan L; Yang, Luhan; He, Aibin; Pasqualini, Francesco Silvio; Agarwal, Ashutosh; Yuan, Hongyan; Jiang, Dawei; Zhang, Donghui; Zangi, Lior; Geva, Judith; Roberts, Amy E; Ma, Qing; Ding, Jian; Chen, Jinghai; Wang, Da-Zhi; Li, Kai; Wang, Nature medicine. 24813252 2014 Jun;
Materials innovation for co-delivery of diverse therapeutic cargos. Godsey, Megan E; Suryaprakash, Smruthi; Leong, Kam W RSC advances. 24818000 2013 Dec 21;
Polymeric stent materials dysregulate macrophage and endothelial cell functions: implications for coronary artery stent. Wang, Xintong; Zachman, Angela L; Chun, Young Wook; Shen, Fang-Wen; Hwang, Yu-Shik; Sung, Hak-Joon International journal of cardiology. 24820736 2014 Jul 1;
A microphysiological system model of therapy for liver micrometastases. Clark, Amanda M; Wheeler, Sarah E; Taylor, Donald P; Pillai, Venkateswaran C; Young, Carissa L; Prantil-Baun, Rachelle; Nguyen, Transon; Stolz, Donna B; Borenstein, Jeffrey T; Lauffenburger, Douglas A; Venkataramanan, Raman; Griffith, Linda G; Wells, Alan Experimental biology and medicine (Maywood, N.J.). 24821820 2014 Sep;
Approaching the in vitro clinical trial: engineering organs on chips. Capulli, A K; Tian, K; Mehandru, N; Bukhta, A; Choudhury, S F; Suchyta, M; Parker, K K Lab on a chip. 24828385 2014 Sep 7;
Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1?. Lin, Hang; Lozito, Thomas P; Alexander, Peter G; Gottardi, Riccardo; Tuan, Rocky S Molecular pharmaceutics. 24830762 2014 Jul 7;
MR cholangiography demonstrates unsuspected rapid biliary clearance of nanoparticles in rodents: implications for clinical translation. Bulte, Jeff W M; Schmieder, Anne H; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory M Nanomedicine : nanotechnology, biology, and medicine. 24832959 2014 Oct;
Multi-scale multi-mechanism design of tough hydrogels: building dissipation into stretchy networks. Zhao, Xuanhe Soft matter. 24834901 2014 Feb 7;
Intracerebral hemorrhage mortality is not changing despite declining incidence. Zahuranec, Darin B; Lisabeth, Lynda D; Sanchez, Brisa N; Smith, Melinda A; Brown, Devin L; Garcia, Nelda M; Skolarus, Lesli E; Meurer, William J; Burke, James F; Adelman, Eric E; Morgenstern, Lewis B Neurology 24838789 2014 Jun 17
Fluid shear stress threshold regulates angiogenic sprouting. Galie, Peter A; Nguyen, Duc-Huy T; Choi, Colin K; Cohen, Daniel M; Janmey, Paul A; Chen, Christopher S Proceedings of the National Academy of Sciences of the United States of America 24843171 2014 Jun 3
Ovarian cancer in endometriosis: clinical and molecular aspects. Lyttle, B; Bernardi, L; Pavone, M E Minerva ginecologica 24848074 2014 Apr
Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury. Chen, Yi-Ting; Chang, Yu-Ting; Pan, Szu-Yu; Chou, Yu-Hsiang; Chang, Fan-Chi; Yeh, Pei-Ying; Liu, Yuan-Hung; Chiang, Wen-Chih; Chen, Yung-Ming; Wu, Kwan-Dun; Tsai, Tun-Jun; Duffield, Jeremy S; Lin, Shuei-Liong Journal of the American Society of Nephrology : JASN 24854266 2014 Dec
Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. Evans, J Corey; Hines, Kelly M; Forsythe, Jay G; Erdogan, Begum; Shi, Mingjian; Hill, Salisha; Rose, Kristie L; McLean, John A; Webb, Donna J Journal of proteome research. 24874604 2014 Jul 3;
Cellular and molecular mechanisms in kidney fibrosis. Duffield, Jeremy S The Journal of clinical investigation 24892703 2014 Jun
Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems. Marasco, Christina C; Goodwin, Cody R; Winder, Danny G; Schramm-Sapyta, Nicole L; McLean, John A; Wikswo, John P Experimental biology and medicine (Maywood, N.J.). 24903164 2014 Nov;
Induced pluripotent stem cells for regenerative medicine. Hirschi, Karen K; Li, Song; Roy, Krishnendu Annual review of biomedical engineering. 24905879 2014 Jul 11;
A multiplexed chip-based assay system for investigating the functional development of human skeletal myotubes in vitro. Smith, A S T; Long, C J; Pirozzi, K; Najjar, S; McAleer, C; Vandenburgh, H H; Hickman, J J Journal of biotechnology. 24909944 2014 Sep 20;
Improved Coarse-Grained Modeling of Cholesterol-Containing Lipid Bilayers. Daily, Michael D; Olsen, Brett N; Schlesinger, Paul H; Ory, Daniel S; Baker, Nathan A Journal of chemical theory and computation. 24910542 2014 May 13;
Biological and medical applications of a brain-on-a-chip. Pamies, David; Hartung, Thomas; Hogberg, Helena T Experimental biology and medicine (Maywood, N.J.). 24912505 2014 Sep;
Physiology and metabolism of tissue-engineered skeletal muscle. Cheng, Cindy S; Davis, Brittany N J; Madden, Lauran; Bursac, Nenad; Truskey, George A Experimental biology and medicine (Maywood, N.J.). 24912506 2014 Sep;
A novel ultrathin collagen nanolayer assembly for 3-D microtissue engineering: Layer-by-layer collagen deposition for long-term stable microfluidic hepatocyte culture. McCarty, William J; Usta, O Berk; Luitje, Martha; Bale, Shyam Sundhar; Bhushan, Abhinav; Hegde, Manjunath; Golberg, Inna; Jindal, Rohit; Yarmush, Martin L Technology. 24932459 2014 Mar;
Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide. Zhou, Hui-fang; Yan, Huimin; Hu, Ying; Springer, Luke E; Yang, Xiaoxia; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T N ACS nano 24941020 2014 Jul 22
Challenges and promises in modeling dermatologic disorders with bioengineered skin. Eungdamrong, Narat J; Higgins, Claire; Guo, Zongyou; Lee, Wen-Han; Gillette, Brian; Sia, Samuel; Christiano, Angela M Experimental biology and medicine (Maywood, N.J.). 24951469 2014 Sep;
Using physiologically-based pharmacokinetic-guided ''body-on-a-chip'' systems to predict mammalian response to drug and chemical exposure. Sung, Jong Hwan; Srinivasan, Balaji; Esch, Mandy Brigitte; McLamb, William T; Bernabini, Catia; Shuler, Michael L; Hickman, James J Experimental biology and medicine (Maywood, N.J.). 24951471 2014 Sep;
Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use. Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Argueta, Lissenya B; Eastaway, Adriene; Cortiella, Joaquin Experimental biology and medicine (Maywood, N.J.). 24962174 2014 Sep;
Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury. Esch, Mandy B; Mahler, Gretchen J; Stokol, Tracy; Shuler, Michael L Lab on a chip. 24970651 2014 Aug 21;
Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases. Alexander, Peter G; Gottardi, Riccardo; Lin, Hang; Lozito, Thomas P; Tuan, Rocky S Experimental biology and medicine (Maywood, N.J.). 24994814 2014 Sep;
What non-neuronal mechanisms should be studied to understand epileptic seizures? Janigro, Damir; Walker, Matthew C Advances in experimental medicine and biology 25012382 2014
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. Alépée, Natalie; Bahinski, Anthony; Daneshian, Mardas; De Wever, Bart; Fritsche, Ellen; Goldberg, Alan; Hansmann, Jan; Hartung, Thomas; Haycock, John; Hogberg, Helena; Hoelting, Lisa; Kelm, Jens M; Kadereit, Suzanne; McVey, Emily; Landsiedel, Robert; Leis ALTEX. 25027500 2014;
Tissue-engineered microenvironment systems for modeling human vasculature. Tourovskaia, Anna; Fauver, Mark; Kramer, Gregory; Simonson, Sara; Neumann, Thomas Experimental biology and medicine (Maywood, N.J.). 25030480 2014 Sep;
Cell and tissue engineering for liver disease. Bhatia, Sangeeta N; Underhill, Gregory H; Zaret, Kenneth S; Fox, Ira J Science translational medicine 25031271 2014 Jul 16
Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery. Gough, Albert H; Chen, Ning; Shun, Tong Ying; Lezon, Timothy R; Boltz, Robert C; Reese, Celeste E; Wagner, Jacob; Vernetti, Lawrence A; Grandis, Jennifer R; Lee, Adrian V; Stern, Andrew M; Schurdak, Mark E; Taylor, D Lansing PloS one. 25036749 2014;
Developing microphysiological systems for use as regulatory tools--challenges and opportunities. Andersen, Melvin E; Betts, Kellyn; Dragan, Yvonne; Fitzpatrick, Suzanne; Goodman, Jesse L; Hartung, Thomas; Himmelfarb, Jonathan; Ingber, Donald E; Jacobs, Abigail; Kavlock, Robert; Kolaja, Kyle; Stevens, James L; Tagle, Dan; Lansing Taylor, D; Throckmort ALTEX. 25061900 2014;
Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes. Freytes, Donald O; O'Neill, John D; Duan-Arnold, Yi; Wrona, Emily A; Vunjak-Novakovic, Gordana Methods in molecular biology (Clifton, N.J.). 25070328 2014;
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems. Shlomai, Amir; Schwartz, Robert E; Ramanan, Vyas; Bhatta, Ankit; de Jong, Ype P; Bhatia, Sangeeta N; Rice, Charles M Proceedings of the National Academy of Sciences of the United States of America. 25092305 2014 Aug 19;
Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation. Nesmith, Alexander Peyton; Agarwal, Ashutosh; McCain, Megan Laura; Parker, Kevin Kit Lab on a chip 25093641 2014 Oct 21
IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study. Wathen, Connor; Janigro, Damir Epilepsia 25099305 2014 Aug
The role of mechanotransduction on vascular smooth muscle myocytes' [corrected] cytoskeleton and contractile function. Ye, George J C; Nesmith, Alexander P; Parker, Kevin Kit Anatomical record (Hoboken, N.J. : 2007) 25125187 2014 Sep
Current progress in Reactive Oxygen Species (ROS)-Responsive materials for biomedical applications. Lee, Sue Hyun; Gupta, Mukesh K; Bang, Jae Beum; Bae, Hojae; Sung, Hak-Joon Advanced healthcare materials. 25136729 2013;
Angiogenesis and airway reactivity in asthmatic Brown Norway rats. Wagner, Elizabeth M; Jenkins, John; Schmieder, Anne; Eldridge, Lindsey; Zhang, Qiong; Moldobaeva, Aigul; Zhang, Huiying; Allen, John S; Yang, Xiaoxia; Mitzner, Wayne; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory M Angiogenesis. 25149641 2015 Jan;
Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels. Zachman, Angela L; Wang, Xintong; Tucker-Schwartz, Jason M; Fitzpatrick, Sean T; Lee, Sue H; Guelcher, Scott A; Skala, Melissa C; Sung, Hak-Joon Biomaterials 25154665 2014 Dec
Balanced UTE-SSFP for 19F MR imaging of complex spectra. Goette, Matthew J; Keupp, Jochen; Rahmer, Jürgen; Lanza, Gregory M; Wickline, Samuel A; Caruthers, Shelton D Magnetic resonance in medicine. 25163853 2015 Aug;
Bond-specific dissociation following excitation energy transfer for distance constraint determination in the gas phase. Hendricks, Nathan G; Lareau, Nichole M; Stow, Sarah M; McLean, John A; Julian, Ryan R Journal of the American Chemical Society 25174489 2014 Sep 24
Design of growth factor sequestering biomaterials. Belair, David G; Le, Ngoc Nhi; Murphy, William L Chemical communications (Cambridge, England). 25182455 2014 Dec 25;
The relevance and potential roles of microphysiological systems in biology and medicine. Wikswo, John P Experimental biology and medicine (Maywood, N.J.) 25187571 2014 Sep
Human vascular tissue models formed from human induced pluripotent stem cell derived endothelial cells. Belair, David G; Whisler, Jordan A; Valdez, Jorge; Velazquez, Jeremy; Molenda, James A; Vickerman, Vernella; Lewis, Rachel; Daigh, Christine; Hansen, Tyler D; Mann, David A; Thomson, James A; Griffith, Linda G; Kamm, Roger D; Schwartz, Michael P; Murphy, William L Stem cell reviews and reports 25190668 2015 Jun
Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases. Hines, Kelly M; Ballard, Billy R; Marshall, Dana R; McLean, John A Molecular bioSystems. 25212505 2014 Nov;
Long-term coculture strategies for primary hepatocytes and liver sinusoidal endothelial cells. Bale, Shyam Sundhar; Golberg, Inna; Jindal, Rohit; McCarty, William J; Luitje, Martha; Hegde, Manjunath; Bhushan, Abhinav; Usta, Osman Berk; Yarmush, Martin L Tissue engineering. Part C, Methods 25233394 2015 Apr
Physicochemical signatures of nanoparticle-dependent complement activation. Thomas, Dennis G; Chikkagoudar, Satish; Heredia-Langer, Alejandro; Tardiff, Mark F; Xu, Zhixiang; Hourcade, Dennis E; Pham, Christine T N; Lanza, Gregory M; Weinberger, Kilian Q; Baker, Nathan A Computational science & discovery. 25254068 2014 Mar 21;
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. Spencer, C Ian; Baba, Shiro; Nakamura, Kenta; Hua, Ethan A; Sears, Marie A F; Fu, Chi-cheng; Zhang, Jianhua; Balijepalli, Sadguna; Tomoda, Kiichiro; Hayashi, Yohei; Lizarraga, Paweena; Wojciak, Julianne; Scheinman, Melvin M; Aalto-Setälä, Katriina; Makiel Stem cell reports. 25254341 2014 Aug 12;
Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression. Boussadia, B; Ghosh, C; Plaud, C; Pascussi, J M; de Bock, F; Rousset, M C; Janigro, D; Marchi, N Neuroscience. 25280786 2014 Oct 2;
The magic touch: endothelial cells muscle-up adipose. Martin, Kathleen A; Hirschi, Karen K Circulation research. 25301822 2014 Oct 10;
A DNA-based molecular probe for optically reporting cellular traction forces. Blakely, Brandon L; Dumelin, Christoph E; Trappmann, Britta; McGregor, Lynn M; Choi, Colin K; Anthony, Peter C; Duesterberg, Van K; Baker, Brendon M; Block, Steven M; Liu, David R; Chen, Christopher S Nature methods. 25306545 2014 Dec;
Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells. Coskun, Suleyman; Chao, Hsu; Vasavada, Hema; Heydari, Kartoosh; Gonzales, Naomi; Zhou, Xin; de Crombrugghe, Benoit; Hirschi, Karen K Cell reports. 25310984 2014 Oct 23;
Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system. Wheeler, S E; Clark, A M; Taylor, D P; Young, C L; Pillai, V C; Stolz, D B; Venkataramanan, R; Lauffenburger, D; Griffith, L; Wells, A British journal of cancer. 25314052 2014 Dec 9;
On-demand hierarchical patterning with electric fields. Wang, Qiming; Robinson, Dominick; Zhao, Xuanhe Applied physics letters. 25316923 2014 Jun 09;
An in vivo model of human small intestine using pluripotent stem cells. Watson, Carey L; Mahe, Maxime M; Múnera, Jorge; Howell, Jonathan C; Sundaram, Nambirajan; Poling, Holly M; Schweitzer, Jamie I; Vallance, Jefferson E; Mayhew, Christopher N; Sun, Ying; Grabowski, Gregory; Finkbeiner, Stacy R; Spence, Jason R; Shroyer, Noa Nature medicine. 25326803 2014 Nov;
Macrophages modulate engineered human tissues for enhanced vascularization and healing. Spiller, Kara L; Freytes, Donald O; Vunjak-Novakovic, Gordana Annals of biomedical engineering 25331098 2015 Mar
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales. Huebsch, Nathaniel; Loskill, Peter; Mandegar, Mohammad A; Marks, Natalie C; Sheehan, Alice S; Ma, Zhen; Mathur, Anurag; Nguyen, Trieu N; Yoo, Jennie C; Judge, Luke M; Spencer, C Ian; Chukka, Anand C; Russell, Caitlin R; So, Po-Lin; Conklin, Bruce R; Healy Tissue engineering. Part C, Methods. 25333967 2015 May;
ROS-cleavable proline oligomer crosslinking of polycaprolactone for pro-angiogenic host response. Lee, Sue Hyun; Boire, Timothy C; Lee, Jung Bok; Gupta, Mukesh K; Zachman, Angela L; Rath, Rutwik; Sung, Hak-Joon Journal of materials chemistry. B, Materials for biology and medicine. 25343029 2014 Nov 7;
Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia. Brown, Jacquelyn A; Sherrod, Stacy D; Goodwin, Cody R; Brewer, Bryson; Yang, Lijie; Garbett, Krassimira A; Li, Deyu; McLean, John A; Wikswo, John P; Mirnics, Károly Journal of neuroinflammation. 25374324 2014;
Photopatterning of hydrogel scaffolds coupled to filter materials using stereolithography for perfused 3D culture of hepatocytes. Neiman, Jaclyn A Shepard; Raman, Ritu; Chan, Vincent; Rhoads, Mary G; Raredon, Micha Sam B; Velazquez, Jeremy J; Dyer, Rachel L; Bashir, Rashid; Hammond, Paula T; Griffith, Linda G Biotechnology and bioengineering. 25384798 2015 Apr;
Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and nontumorigenic human mesenchymal cell types. Hansen, Tyler D; Koepsel, Justin T; Le, Ngoc Nhi; Nguyen, Eric H; Zorn, Stefan; Parlato, Matthew; Loveland, Samuel G; Schwartz, Michael P; Murphy, William L Biomaterials science. 25386339 2014 May;
Patterning vascular networks in vivo for tissue engineering applications. Chaturvedi, Ritika R; Stevens, Kelly R; Solorzano, Ricardo D; Schwartz, Robert E; Eyckmans, Jeroen; Baranski, Jan D; Stapleton, Sarah Chase; Bhatia, Sangeeta N; Chen, Christopher S Tissue engineering. Part C, Methods. 25390971 2015 May;
Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS. Kawakami, Takahisa; Gomez, Ivan G; Ren, Shuyu; Hudkins, Kelly; Roach, Allie; Alpers, Charles E; Shankland, Stuart J; D'Agati, Vivette D; Duffield, Jeremy S Journal of the American Society of Nephrology : JASN 25406339 2015 May
Wavelet-based peak detection and a new charge inference procedure for MS/MS implemented in ProteoWizard's msConvert. French, William R; Zimmerman, Lisa J; Schilling, Birgit; Gibson, Bradford W; Miller, Christine A; Townsend, R Reid; Sherrod, Stacy D; Goodwin, Cody R; McLean, John A; Tabb, David L Journal of proteome research. 25411686 2015 Feb 6;
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways. Gomez, Ivan G; MacKenna, Deidre A; Johnson, Bryce G; Kaimal, Vivek; Roach, Allie M; Ren, Shuyu; Nakagawa, Naoki; Xin, Cuiyan; Newitt, Rick; Pandya, Shweta; Xia, Tai-He; Liu, Xueqing; Borza, Dorin-Bogdan; Grafals, Monica; Shankland, Stuart J; Himmelfarb, J The Journal of clinical investigation. 25415439 2015 Jan;
A CRISPR/Cas9-based system for reprogramming cell lineage specification. Chakraborty, Syandan; Ji, HaYeun; Kabadi, Ami M; Gersbach, Charles A; Christoforou, Nicolas; Leong, Kam W Stem cell reports. 25448066 2014 Dec 9;
Ion mobility-mass spectrometry strategies for untargeted systems, synthetic, and chemical biology. May, Jody C; Goodwin, Cody R; McLean, John A Current opinion in biotechnology. 25462629 2015 Feb;
Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers. Wang, Hailong; Abhilash, A S; Chen, Christopher S; Wells, Rebecca G; Shenoy, Vivek B Biophysical journal. 25468338 2014 Dec 2;
Tenascin-C Signaling in melanoma. Shao, Hanshuang; Kirkwood, John M; Wells, Alan Cell adhesion & migration. 25482624 2015;
Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts. Xing, Qi; Vogt, Caleb; Leong, Kam W; Zhao, Feng Advanced functional materials. 25484849 2014 May 28;
Correction of dystrophin expression in cells from duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases. Ousterout, David G; Kabadi, Ami M; Thakore, Pratiksha I; Perez-Pinera, Pablo; Brown, Matthew T; Majoros, William H; Reddy, Timothy E; Gersbach, Charles A Molecular therapy : the journal of the American Society of Gene Therapy. 25492562 2015 Mar;
Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis. Chakraborty, Syandan; Ji, HaYeun; Chen, Jack; Gersbach, Charles A; Leong, Kam W Scientific reports. 25492703 2014;
Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain. Kabadi, Ami M; Thakore, Pratiksha I; Vockley, Christopher M; Ousterout, David G; Gibson, Tyler M; Guilak, Farshid; Reddy, Timothy E; Gersbach, Charles A ACS synthetic biology. 25494287 2015 Jun 19;
Nanotopography alters nuclear protein expression, proliferation and differentiation of human mesenchymal stem/stromal cells. Kulangara, Karina; Yang, Jennifer; Chellappan, Malathi; Yang, Yong; Leong, Kam W PloS one. 25521962 2014;
Ion mobility-mass spectrometry: time-dispersive instrumentation. May, Jody C; McLean, John A Analytical chemistry. 25526595 2015 Feb 3;
Three-dimensional modeling of the human fallopian tube fimbriae. Eddie, Sharon L; Quartuccio, Suzanne M; Zhu, Jie; Shepherd, Jessica A; Kothari, Rajul; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna E Gynecologic oncology. 25527363 2015 Feb;
Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion. Warita, Katsuhiko; Warita, Tomoko; Beckwitt, Colin H; Schurdak, Mark E; Vazquez, Alexei; Wells, Alan; Oltvai, Zoltán N Scientific reports. 25534349 2014;
Origin and function of cartilage stem/progenitor cells in osteoarthritis. Jiang, Yangzi; Tuan, Rocky S Nature reviews. Rheumatology. 25536487 2015 Apr;
ýýýý*ýýý-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment. Zhang, Ruiying; Pan, Dipanjan; Cai, Xin; Yang, Xiaoxia; Senpan, Angana; Allen, John S; Lanza, Gregory M; Wang, Lihong V Theranostics. 25553103 2015;
Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. Vega, Maria E; Giroux, Véronique; Natsuizaka, Mitsuteru; Liu, Mingen; Klein-Szanto, Andres J; Stairs, Douglas B; Nakagawa, Hiroshi; Wang, Kenneth K; Wang, Timothy C; Lynch, John P; Rustgi, Anil K Cell cycle (Georgetown, Tex.). 25558829 2014;
Nanograting structure promotes lamellipodia-based cell collective migration and wound healing. Chen, Zaozao; Atchison, Leigh; Ji, HaYeun; Leong, Kam W Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 25570601 2014;
Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease. Wilkerson, Irene; Laban, Joshua; Mitchell, Johnathan M; Sheibani, Nader; Alcendor, Donald J Journal of neuroinflammation. 25573478 2015;
Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs. Madden, Lauran; Juhas, Mark; Kraus, William E; Truskey, George A; Bursac, Nenad eLife. 25575180 2015;
Biology coming full circle: joining the whole and the parts. Wikswo, John P; Porter, Andrew P Experimental biology and medicine (Maywood, N.J.). 25583953 2015 Jan;
TEER measurement techniques for in vitro barrier model systems. Srinivasan, Balaji; Kolli, Aditya Reddy; Esch, Mandy Brigitte; Abaci, Hasan Erbil; Shuler, Michael L; Hickman, James J Journal of laboratory automation. 25586998 2015 Apr;
Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair. Jackman, Christopher P; Shadrin, Ilya Y; Carlson, Aaron L; Bursac, Nenad Current opinion in chemical engineering. 25599018 2015 Feb;
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. Kumar, Kevin K; Goodwin, Cody R; Uhouse, Michael A; Bornhorst, Julia; Schwerdtle, Tanja; Aschner, Michael; McLean, John A; Bowman, Aaron B Metallomics : integrated biometal science. 25599126 2015 Feb;
A strategy for combating melanoma with oncogenic c-Myc inhibitors and targeted nanotherapy. Pan, Dipanjan; Kim, Benjamin; Hu, Grace; Gupta, Deepti Sood; Senpan, Angana; Yang, Xiaoxia; Schmieder, Anne; Swain, Corban; Wickline, Samuel A; Tomasson, Michael H; Lanza, Gregory M Nanomedicine (London, England). 25600969 2015 Jan;
Bioengineered tumors. Villasante, Aranzazu; Vunjak-Novakovic, Gordana Bioengineered 25616977 2015
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes. Bal-Price, Anna; Crofton, Kevin M; Leist, Marcel; Allen, Sandra; Arand, Michael; Buetler, Timo; Delrue, Nathalie; FitzGerald, Rex E; Hartung, Thomas; Heinonen, Tuula; Hogberg, Helena; Bennekou, Susanne Hougaard; Lichtensteiger, Walter; Oggier, Daniela; Pa Archives of toxicology. 25618548 2015 Feb;
Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells. Furukawa, Masashi; Wheeler, Sarah; Clark, Amanda M; Wells, Alan PloS one. 25635394 2015;
Novel three dimensional human endocervix cultures respond to 28-day hormone treatment. Arslan, Sevim Yildiz; Yu, Yanni; Burdette, Joanne E; Pavone, Mary Ellen; Hope, Thomas J; Woodruff, Teresa K; Kim, J Julie Endocrinology. 25635622 2015 Apr;
Developmental biology. Regional identity of gut stem cells--one gene to rule them all. Wells, James M Nature reviews. Gastroenterology & hepatology. 25645971 2015 Mar;
Synergy between surface and core entrapped metals in a mixed manganese-gadolinium nanocolloid affords safer MR imaging of sparse biomarkers. Wang, Kezheng; Pan, Dipanjan; Schmieder, Anne H; Senpan, Angana; Hourcade, Dennis E; Pham, Christine T N; Mitchell, Lynne M; Caruthers, Shelton D; Cui, Grace; Wickline, Samuel A; Shen, Baozhong; Lanza, Gregory M Nanomedicine : nanotechnology, biology, and medicine. 25652900 2015 Apr;
Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study. Ghosh, Chaitali; Hossain, Mohammad; Spriggs, Addison; Ghosh, Arnab; Grant, Gerald A; Marchi, Nicola; Perucca, Emilio; Janigro, Damir Epilepsia. 25656284 2015 Mar;
Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro. Ng, Shengyong; Schwartz, Robert E; March, Sandra; Galstian, Ani; Gural, Nil; Shan, Jing; Prabhu, Mythili; Mota, Maria M; Bhatia, Sangeeta N Stem cell reports. 25660406 2015 Mar 10;
CXCR3 in carcinoma progression. Ma, Bo; Khazali, Ahmad; Wells, Alan Histology and histopathology. 25663474 2015 Jul;
S100B blood levels and childhood trauma in adolescent inpatients. Falcone, Tatiana; Janigro, Damir; Lovell, Rachel; Simon, Barry; Brown, Charles A; Herrera, Mariela; Myint, Aye Mu; Anand, Amit Journal of psychiatric research. 25669696 2015 Mar;
Charge Relaxation Dynamics of an Electrolytic Nanocapacitor. Thakore, Vaibhav; Hickman, James J The journal of physical chemistry. C, Nanomaterials and interfaces. 25678941 2015 Jan 29;
Use of an organotypic mammalian in vitro follicle growth assay to facilitate female reproductive toxicity screening. Xu, Yuanming; Duncan, Francesca E; Xu, Min; Woodruff, Teresa K Reproduction, fertility, and development. 25689754 2015 Feb 18;
Development of a low-volume, highly sensitive microimmunoassay using computational fluid dynamics-driven multiobjective optimization. Ghodbane, Mehdi; Kulesa, Anthony; Yu, Henry H; Maguire, Tim J; Schloss, Rene R; Ramachandran, Rohit; Zahn, Jeffrey D; Yarmush, Martin L Microfluidics and nanofluidics. 25691853 2015 Feb;
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy. Ousterout, David G; Kabadi, Ami M; Thakore, Pratiksha I; Majoros, William H; Reddy, Timothy E; Gersbach, Charles A Nature communications. 25692716 2015 Feb 18;
Real-time cellular exometabolome analysis with a microfluidic-mass spectrometry platform. Marasco, Christina C; Enders, Jeffrey R; Seale, Kevin T; McLean, John A; Wikswo, John P PloS one. 25723555 2015;
Structural phenotyping of stem cell-derived cardiomyocytes. Pasqualini, Francesco Silvio; Sheehy, Sean Paul; Agarwal, Ashutosh; Aratyn-Schaus, Yvonne; Parker, Kevin Kit Stem cell reports. 25733020 2015 Mar 10;
Vessel network formation in response to intermittent hypoxia is frequency dependent. Ehsan, Seema M; George, Steven C Journal of bioscience and bioengineering. 25735591 2015 Sep;
Initiation of puberty in mice following decellularized ovary transplant. Laronda, Monica M; Jakus, Adam E; Whelan, Kelly A; Wertheim, Jason A; Shah, Ramille N; Woodruff, Teresa K Biomaterials. 25736492 2015 May;
Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling. Abaci, Hasan Erbil; Shuler, Michael L Integrative biology : quantitative biosciences from nano to macro. 25739725 2015 Apr;
Mechanisms of Barrett's oesophagus: intestinal differentiation, stem cells, and tissue models. Nakagawa, Hiroshi; Whelan, Kelly; Lynch, John P Best practice & research. Clinical gastroenterology. 25743452 2015 Feb;
Human iPSC-based cardiac microphysiological system for drug screening applications. Mathur, Anurag; Loskill, Peter; Shao, Kaifeng; Huebsch, Nathaniel; Hong, SoonGweon; Marcus, Sivan G; Marks, Natalie; Mandegar, Mohammad; Conklin, Bruce R; Lee, Luke P; Healy, Kevin E Scientific reports. 25748532 2015;
Phage-display-guided nanocarrier targeting to atheroprone vasculature. Hofmeister, Lucas H; Lee, Sue Hyun; Norlander, Allison E; Montaniel, Kim Ramil C; Chen, Wei; Harrison, David G; Sung, Hak-Joon ACS nano. 25768046 2015;
Engineering mesenchymal stem cells for regenerative medicine and drug delivery. Park, Ji Sun; Suryaprakash, Smruthi; Lao, Yeh-Hsing; Leong, Kam W Methods (San Diego, Calif.). 25770356 2015 Aug;
Engineering the ovarian cycle using in vitro follicle culture. Skory, Robin M; Xu, Yuanming; Shea, Lonnie D; Woodruff, Teresa K Human reproduction (Oxford, England). 25784584 2015 Jun;
Integration of drug, protein, and gene delivery systems with regenerative medicine. Lorden, Elizabeth R; Levinson, Howard M; Leong, Kam W Drug delivery and translational research. 25787742 2015 Apr;
Generating human intestinal tissues from pluripotent stem cells to study development and disease. Sinagoga, Katie L; Wells, James M The EMBO journal. 25792515 2015 May 5;
Profiling and Imaging Ion Mobility-Mass Spectrometry Analysis of Cholesterol and 7-Dehydrocholesterol in Cells Via Sputtered Silver MALDI. Xu, Libin; Kliman, Michal; Forsythe, Jay G; Korade, Zeljka; Hmelo, Anthony B; Porter, Ned A; McLean, John A Journal of the American Society for Mass Spectrometry. 25822928 2015 Jun;
A cost-effective RNA sequencing protocol for large-scale gene expression studies. Hou, Zhonggang; Jiang, Peng; Swanson, Scott A; Elwell, Angela L; Nguyen, Bao Kim S; Bolin, Jennifer M; Stewart, Ron; Thomson, James A Scientific reports. 25831155 2015;
Culturing adult stem cells from mouse small intestinal crypts. Hamilton, Kathryn E; Crissey, Mary Ann S; Lynch, John P; Rustgi, Anil K Cold Spring Harbor protocols. 25834260 2015 Apr;
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow. Esch, Mandy B; Prot, Jean-Matthieu; Wang, Ying I; Miller, Paula; Llamas-Vidales, Jose Ricardo; Naughton, Brian A; Applegate, Dawn R; Shuler, Michael L Lab on a chip. 25857666 2015 May 21;
The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial: an adaptive trial design case study. Connor, Jason T; Broglio, Kristine R; Durkalski, Valerie; Meurer, William J; Johnston, Karen C Trials. 25885963 2015;
NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection. Juul, Sissel; Obliosca, Judy M; Liu, Cong; Liu, Yen-Liang; Chen, Yu-An; Imphean, Darren M; Knudsen, Birgitta R; Ho, Yi-Ping; Leong, Kam W; Yeh, Hsin-Chih Nanoscale. 25901841 2015 May 14;
Differential ?3 Integrin Expression Regulates the Response of Human Lung and Cardiac Fibroblasts to Extracellular Matrix and Its Components. Merna, Nick; Fung, Kelsey M; Wang, Jean J; King, Cristi R; Hansen, Kirk C; Christman, Karen L; George, Steven C Tissue engineering. Part A. 25926101 2015 Aug;
Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor. Sarkar, Ujjal; Rivera-Burgos, Dinelia; Large, Emma M; Hughes, David J; Ravindra, Kodihalli C; Dyer, Rachel L; Ebrahimkhani, Mohammad R; Wishnok, John S; Griffith, Linda G; Tannenbaum, Steven R Drug metabolism and disposition: the biological fate of chemicals. 25926431 2015 Jul;
Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis. Legocki, Laurie J; Meurer, William J; Frederiksen, Shirley; Lewis, Roger J; Durkalski, Valerie L; Berry, Donald A; Barsan, William G; Fetters, Michael D BMC medical ethics. 25933921 2015;
Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues. Feric, Nicole T; Radisic, Milica Advanced drug delivery reviews. 25956564 2015 May 5;
Structural Characterization of Methylenedianiline Regioisomers by Ion Mobility-Mass Spectrometry, Tandem Mass Spectrometry, and Computational Strategies. 2. Electrospray Spectra of 3-Ring and 4-Ring Isomers. Stow, Sarah M; Onifer, Tiffany M; Forsythe, Jay G; Nefzger, Hartmut; Kwiecien, Nicholas W; May, Jody C; McLean, John A; Hercules, David M Analytical chemistry. 25971782 2015 Jun 16;
A phenotypic in vitro model for the main determinants of human whole heart function. Stancescu, Maria; Molnar, Peter; McAleer, Christopher W; McLamb, William; Long, Christopher J; Oleaga, Carlota; Prot, Jean-Matthieu; Hickman, James J Biomaterials. 25978005 2015 Aug;
Fluorescent protein biosensors applied to microphysiological systems. Senutovitch, Nina; Vernetti, Lawrence; Boltz, Robert; DeBiasio, Richard; Gough, Albert; Taylor, D Lansing Experimental biology and medicine (Maywood, N.J.). 25990438 2015 Jun;
Fluorescence lifetime imaging of endogenous biomarker of oxidative stress. Datta, Rupsa; Alfonso-García, Alba; Cinco, Rachel; Gratton, Enrico Scientific reports. 25993434 2015;
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. Chen, Huanhuan Joyce; Sun, Jian; Huang, Zhiliang; Hou Jr, Harry; Arcilla, Myra; Rakhilin, Nikolai; Joe, Daniel J; Choi, Jiahn; Gadamsetty, Poornima; Milsom, Jeff; Nandakumar, Govind; Longman, Randy; Zhou, Xi Kathy; Edwards, Robert; Chen, Jonlin; Chen, Kai Nature biotechnology. 26006007 2015 Jun;
MicroRNA delivery for regenerative medicine. Peng, Bo; Chen, Yongming; Leong, Kam W Advanced drug delivery reviews. 26024978 2015 Jul 1;
Tissue-engineered blood vessels as promising tools for testing drug toxicity. Truskey, George A; Fernandez, Cristina E Expert opinion on drug metabolism & toxicology. 26028128 2015 Jul;
3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures. Hong, Sungmin; Sycks, Dalton; Chan, Hon Fai; Lin, Shaoting; Lopez, Gabriel P; Guilak, Farshid; Leong, Kam W; Zhao, Xuanhe Advanced materials (Deerfield Beach, Fla.). 26033288 2015 Jul 15;
The state of the heart: Recent advances in engineering human cardiac tissue from pluripotent stem cells. Sirabella, Dario; Cimetta, Elisa; Vunjak-Novakovic, Gordana Experimental biology and medicine (Maywood, N.J.) 26069271 2015 Aug
Comparative hazard analysis and toxicological modeling of diverse nanomaterials using the embryonic zebrafish (EZ) metric of toxicity. Harper, Bryan; Thomas, Dennis; Chikkagoudar, Satish; Baker, Nathan; Tang, Kaizhi; Heredia-Langner, Alejandro; Lins, Roberto; Harper, Stacey Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology. 26069453 2015;
Blood-brain barrier, bulk flow, and interstitial clearance in epilepsy. Marchi, Nicola; Banjara, Manoj; Janigro, Damir Journal of neuroscience methods 26093166 2016 Feb 15
Covalent Modification of Synthetic Hydrogels with Bioactive Proteins via Sortase-Mediated Ligation. Cambria, Elena; Renggli, Kasper; Ahrens, Caroline C; Cook, Christi D; Kroll, Carsten; Krueger, Andrew T; Imperiali, Barbara; Griffith, Linda G Biomacromolecules 26098148 2015 Aug 10
Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors. Bagley, Alexander F; Scherz-Shouval, Ruth; Galie, Peter A; Zhang, Angela Q; Wyckoff, Jeffrey; Whitesell, Luke; Chen, Christopher S; Lindquist, Susan; Bhatia, Sangeeta N Cancer research. 26122846 2015 Aug 15;
Real-Time Monitoring of Cellular Bioenergetics with a Multianalyte Screen-Printed Electrode. McKenzie, Jennifer R; Cognata, Andrew C; Davis, Anna N; Wikswo, John P; Cliffel, David E Analytical chemistry. 26125545 2015 Aug 4;
Development and validation of a microfluidic immunoassay capable of multiplexing parallel samples in microliter volumes. Ghodbane, Mehdi; Stucky, Elizabeth C; Maguire, Tim J; Schloss, Rene S; Shreiber, David I; Zahn, Jeffrey D; Yarmush, Martin L Lab on a chip. 26130452 2015 Aug 7;
Note: A single-chamber tool for plasma activation and surface functionalization in microfabrication. Bowman, Adam J; Scherrer, Joseph R; Reiserer, Ronald S The Review of scientific instruments 26133881 2015 Jun
Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs. Lee, Eugene K; Kurokawa, Yosuke K; Tu, Robin; George, Steven C; Khine, Michelle Scientific reports 26139150 2015 Jul 03
Biotunable acoustic node assembly of organoids. Chen, Pu; Güven, Sinan; Usta, Osman Berk; Yarmush, Martin L; Demirci, Utkan Advanced healthcare materials. 26149464 2015 Sep 16;
Bioengineering methods for myocardial regeneration. Parsa, Hesam; Ronaldson, Kacey; Vunjak-Novakovic, Gordana Advanced drug delivery reviews. 26150344 2015 Jul 4;
Long-term maintenance of a microfluidic 3D human liver sinusoid. Prodanov, Ljupcho; Jindal, Rohit; Bale, Shyam Sundhar; Hegde, Manjunath; McCarty, William J; Golberg, Inna; Bhushan, Abhinav; Yarmush, Martin L; Usta, Osman Berk Biotechnology and bioengineering. 26152452 2016 Jan;
Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies. Usta, O B; McCarty, W J; Bale, S; Hegde, M; Jindal, R; Bhushan, A; Golberg, I; Yarmush, M L Technology. 26167518 2015 Mar;
Endometriosis and ovarian cancer: links, risks, and challenges faced. Pavone, Mary Ellen; Lyttle, Brianna M International journal of women's health. 26170722 2015;
Self-organizing human cardiac microchambers mediated by geometric confinement. Ma, Zhen; Wang, Jason; Loskill, Peter; Huebsch, Nathaniel; Koo, Sangmo; Svedlund, Felicia L; Marks, Natalie C; Hua, Ethan W; Grigoropoulos, Costas P; Conklin, Bruce R; Healy, Kevin E Nature communications 26172574 2015 Jul 14
3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures. Hong, Sungmin; Sycks, Dalton; Chan, Hon Fai; Lin, Shaoting; Lopez, Gabriel P; Guilak, Farshid; Leong, Kam W; Zhao, Xuanhe Advanced materials (Deerfield Beach, Fla.). 26172844 2015 Jul 15;
Microfluidic device to control interstitial flow-mediated homotypic and heterotypic cellular communication. Alonzo, Luis F; Moya, Monica L; Shirure, Venktesh S; George, Steven C Lab on a chip. 26190172 2015 Sep 7;
Broadscale resolving power performance of a high precision uniform field ion mobility-mass spectrometer. May, Jody C; Dodds, James N; Kurulugama, Ruwan T; Stafford, George C; Fjeldsted, John C; McLean, John A The Analyst. 26191544 2015 Oct 21;
MALDI-TOF/TOF CID Study of Poly(1,4-dihydroxybenzene terephthalate) Fragmentation Reactions. Gies, Anthony P; Stow, Sarah M; McLean, John A; Hercules, David M Polymer 26195848 2015 May 01
A human liver microphysiology platform for investigating physiology, drug safety, and disease models. Vernetti, Lawrence A; Senutovitch, Nina; Boltz, Robert; DeBiasio, Richard; Ying Shun, Tong; Gough, Albert; Taylor, D Lansing Experimental biology and medicine (Maywood, N.J.). 26202373 2016 Jan;
Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes. Chun, Young Wook; Balikov, Daniel A; Feaster, Tromondae K; Williams, Charles H; Sheng, Calvin C; Lee, Jung-Bok; Boire, Timothy C; Neely, M Diana; Bellan, Leon M; Ess, Kevin C; Bowman, Aaron B; Sung, Hak-Joon; Hong, Charles C Biomaterials. 26204225 2015 Oct;
Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening. Kurokawa, Yosuke K; George, Steven C Advanced drug delivery reviews 26212156 2016 Jan 15
Micropatterning Alginate Substrates for in vitro Cardiovascular Muscle on a Chip. Agarwal, Ashutosh; Farouz, Yohan; Nesmith, Alexander Peyton; Deravi, Leila F; McCain, Megan Laura; Parker, Kevin Kit Advanced functional materials. 26213529 2013 Aug 12;
Use of ChemoFx® for Identification of Effective Treatments in Epithelial Ovarian Cancer. Richard, Scott; Wells, Alan; Connor, Joseph; Price, Fredric PLoS currents 26213638 2015 Jul 13
A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro. Adler, Melanie; Ramm, Susanne; Hafner, Marc; Muhlich, Jeremy L; Gottwald, Esther Maria; Weber, Elijah; Jaklic, Alenka; Ajay, Amrendra Kumar; Svoboda, Daniel; Auerbach, Scott; Kelly, Edward J; Himmelfarb, Jonathan; Vaidya, Vishal S Journal of the American Society of Nephrology : JASN. 26260164 2016 Apr;
Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments. Leng, Ning; Chu, Li-Fang; Barry, Chris; Li, Yuan; Choi, Jeea; Li, Xiaomao; Jiang, Peng; Stewart, Ron M; Thomson, James A; Kendziorski, Christina Nature methods. 26301841 2015 Oct;
Melanin Transfer in Human 3D Skin Equivalents Generated Exclusively from Induced Pluripotent Stem Cells. Gledhill, Karl; Guo, Zongyou; Umegaki-Arao, Noriko; Higgins, Claire A; Itoh, Munenari; Christiano, Angela M PloS one. 26308443 2015;
The FOXD1 lineage of kidney perivascular cells and myofibroblasts: functions and responses to injury. Gomez, Ivan G; Duffield, Jeremy S Kidney international supplements. 26312147 2014 Nov;
HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy. Hinson, John T; Chopra, Anant; Nafissi, Navid; Polacheck, William J; Benson, Craig C; Swist, Sandra; Gorham, Joshua; Yang, Luhan; Schafer, Sebastian; Sheng, Calvin C; Haghighi, Alireza; Homsy, Jason; Hubner, Norbert; Church, George; Cook, Stuart A; Linke, Wolfgang A; Chen, Christopher S; Seidman, J G; Seidman, Christine E Science (New York, N.Y.) 26315439 2015 Aug 28
Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems. Berry, Bonnie J; Akanda, Nesar; Smith, Alec S T; Long, Christopher J; Schnepper, Mark T; Guo, Xiufang; Hickman, James J Biotechnology progress. 26317319 2015 Nov-Dec;
In Situ Crosslinkable Gelatin Hydrogels for Vasculogenic Induction and Delivery of Mesenchymal Stem Cells. Lee, Sue Hyun; Lee, Yunki; Chun, Young Wook; Crowder, Spencer W; Young, Pampee P; Park, Ki Dong; Sung, Hak-Joon Advanced functional materials. 26327818 2014 Nov 19;
Projection Stereolithographic Fabrication of Human Adipose Stem Cell-Incorporated Biodegradable Scaffolds for Cartilage Tissue Engineering. Sun, Aaron X; Lin, Hang; Beck, Angela M; Kilroy, Evan J; Tuan, Rocky S Frontiers in bioengineering and biotechnology. 26347860 2015;
Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress. Kong, Jianping; Whelan, Kelly A; Laczkó, Dorottya; Dang, Brendan; Caro Monroig, Angeliz; Soroush, Ali; Falcone, John; Amaravadi, Ravi K; Rustgi, Anil K; Ginsberg, Gregory G; Falk, Gary W; Nakagawa, Hiroshi; Lynch, John P Molecular carcinogenesis. 26373456 2015 Sep 16;
Hydrogel arrays formed via differential wettability patterning enable combinatorial screening of stem cell behavior. Le, Ngoc Nhi T; Zorn, Stefan; Schmitt, Samantha K; Gopalan, Padma; Murphy, William L Acta biomaterialia. 26386315 2016 Apr 1;
Human pluripotent stem cell-derived neural constructs for predicting neural toxicity. Schwartz, Michael P; Hou, Zhonggang; Propson, Nicholas E; Zhang, Jue; Engstrom, Collin J; Santos Costa, Vitor; Jiang, Peng; Nguyen, Bao Kim; Bolin, Jennifer M; Daly, William; Wang, Yu; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James A Proceedings of the National Academy of Sciences of the United States of America. 26392547 2015 Oct 6;
Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin. Pellett, Sabine; Schwartz, Michael P; Tepp, William H; Josephson, Richard; Scherf, Jacob M; Pier, Christina L; Thomson, James A; Murphy, William L; Johnson, Eric A Scientific reports. 26411797 2015;
In vitro cardiac tissue models: Current status and future prospects. Mathur, Anurag; Ma, Zhen; Loskill, Peter; Jeeawoody, Shaheen; Healy, Kevin E Advanced drug delivery reviews. 26428618 2016 Jan 15;
Enabling functional genomics with genome engineering. Hilton, Isaac B; Gersbach, Charles A Genome research. 26430154 2015 Oct;
The Development of TALE Nucleases for Biotechnology. Ousterout, David G; Gersbach, Charles A Methods in molecular biology (Clifton, N.J.). 26443211 2016;
Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors. Thakore, Pratiksha I; Gersbach, Charles A Methods in molecular biology (Clifton, N.J.). 26443215 2016;
Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology. Saxena, Kapil; Blutt, Sarah E; Ettayebi, Khalil; Zeng, Xi-Lei; Broughman, James R; Crawford, Sue E; Karandikar, Umesh C; Sastri, Narayan P; Conner, Margaret E; Opekun, Antone R; Graham, David Y; Qureshi, Waqar; Sherman, Vadim; Foulke-Abel, Jennifer; In, J Journal of virology. 26446608 2015 Oct 07;
RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis. Craciun, Florin L; Bijol, Vanesa; Ajay, Amrendra K; Rao, Poornima; Kumar, Ramya K; Hutchinson, John; Hofmann, Oliver; Joshi, Nikita; Luyendyk, James P; Kusebauch, Ulrike; Moss, Christopher L; Srivastava, Anand; Himmelfarb, Jonathan; Waikar, Sushrut S; Moritz, Robert L; Vaidya, Vishal S Journal of the American Society of Nephrology : JASN. 26449608 2016 Jun;
Systems-Wide High-Dimensional Data Acquisition and Informatics Using Structural Mass Spectrometry Strategies. Sherrod, Stacy D; McLean, John A Clinical chemistry. 26453699 2016 Jan;
Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. Jung, Youngmee; Ji, HaYeun; Chen, Zaozao; Fai Chan, Hon; Atchison, Leigh; Klitzman, Bruce; Truskey, George; Leong, Kam W Scientific reports. 26456074 2015;
Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia. Kong, Jianping; Sai, Hong; Crissey, Mary Ann S; Jhala, Nirag; Falk, Gary W; Ginsberg, Gregory G; Abrams, Julian A; Nakagawa, Hiroshi; Wang, Kenneth; Rustgi, Anil K; Wang, Timothy C; Lynch, John P Oncotarget. 26460825 2015 Oct 20;
Patterned polymer matrix promotes stemness and cell-cell interaction of adult stem cells. Hofmeister, Lucas H; Costa, Lino; Balikov, Daniel A; Crowder, Spencer W; Terekhov, Alexander; Sung, Hak-Joon; Hofmeister, William H Journal of biological engineering. 26464581 2015;
Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain depends on disease status. Chun, Young Wook; Voyles, David E; Rath, Rutwik; Hofmeister, Lucas H; Boire, Timothy C; Wilcox, Henry; Lee, Jae Han; Bellan, Leon M; Hong, Charles C; Sung, Hak-Joon Journal of biomechanics. 26476764 2015 Nov 5;
Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization. McCarty, William J; Prodanov, Ljupcho; Bale, Shyam Sundhar; Bhushan, Abhinav; Jindal, Rohit; Yarmush, Martin L; Usta, O Berk Journal of visualized experiments : JoVE. 26485274 2015;
Physiome-on-a-Chip: The Challenge of "Scaling" in Design, Operation, and Translation of Microphysiological Systems. Stokes, C L; Cirit, M; Lauffenburger, D A CPT: pharmacometrics & systems pharmacology 26535154 2015 Oct
Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration. Yu, J; Cilfone, N A; Large, E M; Sarkar, U; Wishnok, J S; Tannenbaum, S R; Hughes, D J; Lauffenburger, D A; Griffith, L G; Stokes, C L; Cirit, M CPT: pharmacometrics & systems pharmacology 26535159 2015 Oct
Tough bonding of hydrogels to diverse non-porous surfaces. Yuk, Hyunwoo; Zhang, Teng; Lin, Shaoting; Parada, German Alberto; Zhao, Xuanhe Nature materials. 26552058 2016 Feb;
Is phosphorylated tau unique to chronic traumatic encephalopathy? Phosphorylated tau in epileptic brain and chronic traumatic encephalopathy. Puvenna, Vikram; Engeler, Madeline; Banjara, Manoj; Brennan, Chanda; Schreiber, Peter; Dadas, Aaron; Bahrami, Ashkon; Solanki, Jesal; Bandyopadhyay, Anasua; Morris, Jacqueline K; Bernick, Charles; Ghosh, Chaitali; Rapp, Edward; Bazarian, Jeffrey J; Janigr Brain research. 26556772 2016 Jan 1;
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor. Brown, Jacquelyn A; Pensabene, Virginia; Markov, Dmitry A; Allwardt, Vanessa; Neely, M Diana; Shi, Mingjian; Britt, Clayton M; Hoilett, Orlando S; Yang, Qing; Brewer, Bryson M; Samson, Philip C; McCawley, Lisa J; May, James M; Webb, Donna J; Li, Deyu; Bow Biomicrofluidics. 26576206 2015 Sep;
Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1?/nerve growth factor signaling. Jiang, Yangzi; Hu, Changchang; Yu, Shuting; Yan, Junwei; Peng, Hsuan; Ouyang, Hong Wei; Tuan, Rocky S Arthritis research & therapy. 26577823 2015;
Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model. Rivera-Burgos, Dinelia; Sarkar, Ujjal; Lever, Amanda R; Avram, Michael J; Coppeta, Jonathan R; Wishnok, John S; Borenstein, Jeffrey T; Tannenbaum, Steven R Drug metabolism and disposition: the biological fate of chemicals. 26586376 2016 Feb;
Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels. Wang, Xiaolin; Phan, Duc T T; Sobrino, Agua; George, Steven C; Hughes, Christopher C W; Lee, Abraham P Lab on a chip 26616908 2016 Jan 21
Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study. Guetterman, Timothy C; Fetters, Michael D; Legocki, Laurie J; Mawocha, Samkeliso; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J Clinical research and regulatory affairs. 26622163 2015 Oct 2;
Novel behavior of the chromatographic separation of linear and cyclic polymers. Montenegro-Burke, J Rafael; Bennett, Jackson M; McLean, John A; Hercules, David M Analytical and bioanalytical chemistry. 26637218 2016 Jan;
Stretchable Hydrogel Electronics and Devices. Lin, Shaoting; Yuk, Hyunwoo; Zhang, Teng; Parada, German Alberto; Koo, Hyunwoo; Yu, Cunjiang; Zhao, Xuanhe Advanced materials (Deerfield Beach, Fla.). 26639322 2015 Dec 7;
Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease. Bursac, Nenad; Juhas, Mark; Rando, Thomas A Annual review of biomedical engineering 26643021 2015
A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis. Smirnova, L; Harris, G; Delp, J; Valadares, M; Pamies, D; Hogberg, H T; Waldmann, T; Leist, M; Hartung, T Archives of toxicology. 26647301 2016 Nov;
Fibrous scaffolds for building hearts and heart parts. Capulli, A K; MacQueen, L A; Sheehy, Sean P; Parker, K K Advanced drug delivery reviews. 26656602 2016 Jan 15;
A Novel Three-Dimensional Human Peritubular Microvascular System. Ligresti, Giovanni; Nagao, Ryan J; Xue, Jun; Choi, Yoon Jung; Xu, Jin; Ren, Shuyu; Aburatani, Takahide; Anderson, Susan K; MacDonald, James W; Bammler, Theo K; Schwartz, Stephen M; Muczynski, Kimberly A; Duffield, Jeremy S; Himmelfarb, Jonathan; Zheng, Yi Journal of the American Society of Nephrology : JASN. 26657868 2016 Aug;
Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology. Zachos, Nicholas C; Kovbasnjuk, Olga; Foulke-Abel, Jennifer; In, Julie; Blutt, Sarah E; de Jonge, Hugo R; Estes, Mary K; Donowitz, Mark The Journal of biological chemistry. 26677228 2016 Feb 19;
Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. Foulke-Abel, Jennifer; In, Julie; Yin, Jianyi; Zachos, Nicholas C; Kovbasnjuk, Olga; Estes, Mary K; de Jonge, Hugo; Donowitz, Mark Gastroenterology. 26677983 2016 Mar;
Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification. Logan, David J; Shan, Jing; Bhatia, Sangeeta N; Carpenter, Anne E Methods (San Diego, Calif.). 26687239 2016 Mar 1;
Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Heylman, Christopher; Datta, Rupsa; Sobrino, Agua; George, Steven; Gratton, Enrico PloS one 26695765 2015
Liver-Regenerative Transplantation: Regrow and Reset. Collin de l'Hortet, A; Takeishi, K; Guzman-Lepe, J; Handa, K; Matsubara, K; Fukumitsu, K; Dorko, K; Presnell, S C; Yagi, H; Soto-Gutierrez, A American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 26699680 2016 Jun
Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism. Yamaura, Yoshiyuki; Chapron, Brian D; Wang, Zhican; Himmelfarb, Jonathan; Thummel, Kenneth E Drug metabolism and disposition: the biological fate of chemicals. 26700954 2016 Mar;
Tissue Engineering and Regenerative Medicine 2015: A Year in Review. Wobma, Holly; Vunjak-Novakovic, Gordana Tissue engineering. Part B, Reviews. 26714410 2016 Apr;
Tissue-Engineering for the Study of Cardiac Biomechanics. Ma, Stephen P; Vunjak-Novakovic, Gordana Journal of biomechanical engineering. 26720588 2016 Feb;
OEFinder: a user interface to identify and visualize ordering effects in single-cell RNA-seq data. Leng, Ning; Choi, Jeea; Chu, Li-Fang; Thomson, James A; Kendziorski, Christina; Stewart, Ron Bioinformatics (Oxford, England). 26743507 2016 May 01;
Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Eng, George; Lee, Benjamin W; Protas, Lev; Gagliardi, Mark; Brown, Kristy; Kass, Robert S; Keller, Gordon; Robinson, Richard B; Vunjak-Novakovic, Gordana Nature communications 26785135 2016 Jan 19
High-density lipoprotein subclass measurements improve mortality risk prediction, discrimination and reclassification in a cardiac catheterization cohort. McGarrah, Robert W; Craig, Damian M; Haynes, Carol; Dowdy, Z Elaine; Shah, Svati H; Kraus, William E Atherosclerosis. 26803432 2016 Mar;
Angiotensin II Induced Cardiac Dysfunction on a Chip. Horton, Renita E; Yadid, Moran; McCain, Megan L; Sheehy, Sean P; Pasqualini, Francesco S; Park, Sung-Jin; Cho, Alexander; Campbell, Patrick; Parker, Kevin Kit PloS one 26808388 2016
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs. Oleaga, Carlota; Bernabini, Catia; Smith, Alec S T; Srinivasan, Balaji; Jackson, Max; McLamb, William; Platt, Vivien; Bridges, Richard; Cai, Yunqing; Santhanam, Navaneetha; Berry, Bonnie; Najjar, Sarah; Akanda, Nesar; Guo, Xiufang; Martin, Candace; Ekman, Scientific reports. 26837601 2016;
Enterohemorrhagic Escherichia coli reduce mucus and intermicrovillar bridges in human stem cell-derived colonoids. In, Julie; Foulke-Abel, Jennifer; Zachos, Nicholas C; Hansen, Anne-Marie; Kaper, James B; Bernstein, Harris D; Halushka, Marc; Blutt, Sarah; Estes, Mary K; Donowitz, Mark; Kovbasnjuk, Olga Cellular and molecular gastroenterology and hepatology. 26855967 2016 Jan 1;
Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy. Aratyn-Schaus, Yvonne; Pasqualini, Francesco S; Yuan, Hongyan; McCain, Megan L; Ye, George J C; Sheehy, Sean P; Campbell, Patrick H; Parker, Kevin Kit The Journal of cell biology. 26858266 2016 Feb 15;
Modular Assembly Approach to Engineer Geometrically Precise Cardiovascular Tissue. Lee, Benjamin W; Liu, Bohao; Pluchinsky, Adam; Kim, Nathan; Eng, George; Vunjak-Novakovic, Gordana Advanced healthcare materials. 26865105 2016 Apr;
Transdifferentiation of human endothelial progenitors into smooth muscle cells. Ji, HaYeun; Atchison, Leigh; Chen, Zaozao; Chakraborty, Syandan; Jung, Youngmee; Truskey, George A; Christoforou, Nicolas; Leong, Kam W Biomaterials. 26874281 2016 Apr;
Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators. Moyle-Heyrman, Georgette; Schipma, Matthew J; Dean, Matthew; Davis, David A; Burdette, Joanna E Journal of ovarian research. 26879975 2016 Feb 15;
Human Vascular Microphysiological System for in vitro Drug Screening. Fernandez, C E; Yen, R W; Perez, S M; Bedell, H W; Povsic, T J; Reichert, W M; Truskey, G A Scientific reports 26888719 2016 Feb 18
SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. Tobita, Takamasa; Guzman-Lepe, Jorge; Takeishi, Kazuki; Nakao, Toshimasa; Wang, Yang; Meng, Fanying; Deng, Chu-Xia; Collin de l'Hortet, Alexandra; Soto-Gutierrez, Alejandro PloS one 26890260 2016
Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. Cheng, Cindy S; Ran, Lydia; Bursac, Nenad; Kraus, William E; Truskey, George A Tissue engineering. Part A. 26891613 2016 Apr;
A novel low-volume two-chamber microfabricated platform for evaluating drug metabolism and toxicity. Bale, Shyam Sundhar; Sridharan, Gautham Vivek; Golberg, Inna; Prodanov, Ljupcho; McCarty, William J; Usta, Osman Berk; Jindal, Rohit; Yarmush, Martin L Technology. 26925437 2015 Dec;
Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels. Zanotelli, Matthew R; Ardalani, Hamisha; Zhang, Jue; Hou, Zhonggang; Nguyen, Eric H; Swanson, Scott; Nguyen, Bao Kim; Bolin, Jennifer; Elwell, Angela; Bischel, Lauren L; Xie, Angela W; Stewart, Ron; Beebe, David J; Thomson, James A; Schwartz, Michael P; Murphy, William L Acta biomaterialia. 26945632 2016 Apr 15;
A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine. Stern, Andrew M; Schurdak, Mark E; Bahar, Ivet; Berg, Jeremy M; Taylor, D Lansing Journal of biomolecular screening. 26962875 2016 Jul;
TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease. Gomez, Ivan G; Roach, Allie M; Nakagawa, Naoki; Amatucci, Aldo; Johnson, Bryce G; Dunn, Kadeshia; Kelly, Mark C; Karaca, Gamze; Zheng, Timothy S; Szak, Suzanne; Peppiatt-Wildman, Claire M; Burkly, Linda C; Duffield, Jeremy S Journal of the American Society of Nephrology : JASN. 27026366 ;
Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions. Chan, Hon Fai; Zhang, Ying; Leong, Kam W Small (Weinheim an der Bergstrasse, Germany). 27038291 2016 May;
Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies? Chan, Hon Fai; Ma, Siying; Leong, Kam W Regenerative biomaterials. 27047674 2016 Jun;
Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Huebsch, Nathaniel; Loskill, Peter; Deveshwar, Nikhil; Spencer, C Ian; Judge, Luke M; Mandegar, Mohammad A; Fox, Cade B; Mohamed, Tamer M A; Ma, Zhen; Mathur, Anurag; Sheehan, Alice M; Truong, Annie; Saxton, Mike; Yoo, Jennie; Srivastava, Deepak; Desai, Tejal A; So, Po-Lin; Healy, Kevin E; Conklin, Bruce R Scientific reports. 27095412 2016;
Bioengineered Models of Solid Human Tumors for Cancer Research. Marturano-Kruik, Alessandro; Villasante, Aranzazu; Vunjak-Novakovic, Gordana Methods in molecular biology (Clifton, N.J.). 27115504 2016 Apr 27;
Human Cartilage-Derived Progenitor Cells From Committed Chondrocytes for Efficient Cartilage Repair and Regeneration. Jiang, Yangzi; Cai, Youzhi; Zhang, Wei; Yin, Zi; Hu, Changchang; Tong, Tong; Lu, Ping; Zhang, Shufang; Neculai, Dante; Tuan, Rocky S; Ouyang, Hong Wei Stem cells translational medicine. 27130221 2016 Jun;
Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response. Bale, Shyam Sundhar; Geerts, Sharon; Jindal, Rohit; Yarmush, Martin L Scientific reports. 27142224 2016 May 04;
Modeling tumor microenvironments using custom-designed biomaterial scaffolds. Liu, Zen; Vunjak-Novakovic, Gordana Current opinion in chemical engineering. 27152253 2016 Feb;
Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro. Capulli, Andrew K; MacQueen, Luke A; O'Connor, Blakely B; Dauth, Stephanie; Parker, Kevin Kit Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 27174867 2016 Jul-Aug;
Forces and mechanotransduction in 3D vascular biology. Kutys, Matthew L; Chen, Christopher S Current opinion in cell biology. 27209346 2016 May 19;
Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes. Datta, Rupsa; Heylman, Christopher; George, Steven C; Gratton, Enrico Biomedical optics express 27231614 2016 May 01
A Microfabricated Platform for Generating Physiologically-Relevant Hepatocyte Zonation. McCarty, William J; Usta, O Berk; Yarmush, Martin L Scientific reports. 27240736 2016 May 31;
Striated muscle function, regeneration, and repair. Shadrin, I Y; Khodabukus, A; Bursac, N Cellular and molecular life sciences : CMLS. 27271751 2016 Jun 6;
Recapitulating the Size and Cargo of Tumor Exosomes in a Tissue-Engineered Model. Villasante, Aranzazu; Marturano-Kruik, Alessandro; Ambati, Srikanth R; Liu, Zen; Godier-Furnemont, Amandine; Parsa, Hesam; Lee, Benjamin W; Moore, Malcolm A S; Vunjak-Novakovic, Gordana Theranostics. 27279906 2016;
Distilling complexity to advance cardiac tissue engineering. Ogle, Brenda M; Bursac, Nenad; Domian, Ibrahim; Huang, Ngan F; Menasché, Philippe; Murry, Charles E; Pruitt, Beth; Radisic, Milica; Wu, Joseph C; Wu, Sean M; Zhang, Jianyi; Zimmermann, Wolfram-Hubertus; Vunjak-Novakovic, Gordana Science translational medicine 27280684 2016 Jun 08
Automated detection and analysis of depolarization events in human cardiomyocytes using MaDEC. Szymanska, Agnieszka F; Heylman, Christopher; Datta, Rupsa; Gratton, Enrico; Nenadic, Zoran Computers in biology and medicine. 27281718 2016 Aug 1;
Engineering a perfusable 3D human liver platform from iPS cells. Schepers, Arnout; Li, Cheri; Chhabra, Arnav; Seney, Benjamin Tschudy; Bhatia, Sangeeta Lab on a chip. 27296616 2016 Jul 5;
Advancing cardiovascular tissue engineering. Truskey, George A F1000Research 27303643 2016
Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge. May, Jody C; McLean, John A Annual review of analytical chemistry (Palo Alto, Calif.). 27306312 2016 Jun 12;
Pathophysiological implications of neurovascular P450 in brain disorders. Ghosh, Chaitali; Hossain, Mohammed; Solanki, Jesal; Dadas, Aaron; Marchi, Nicola; Janigro, Damir Drug discovery today. 27312874 2016 Jun 14;
Evaluation of Collision Cross Section Calibrants for Structural Analysis of Lipids by Traveling Wave Ion Mobility-Mass Spectrometry. Hines, Kelly M; May, Jody C; McLean, John A; Xu, Libin Analytical chemistry. 27321977 2016 Jul 19;
Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC-Derived Endothelial Cells. Abaci, Hasan E; Guo, Zongyou; Coffman, Abigail; Gillette, Brian; Lee, Wen-Han; Sia, Samuel K; Christiano, Angela M Advanced healthcare materials. 27333469 2016 Jul;
Isolation of Murine Embryonic Hemogenic Endothelial Cells. Fang, Jennifer S; Gritz, Emily C; Marcelo, Kathrina L; Hirschi, Karen K Journal of visualized experiments : JoVE. 27341393 2016 06 17;
Skin-inspired hydrogel-elastomer hybrids with robust interfaces and functional microstructures. Yuk, Hyunwoo; Zhang, Teng; Parada, German Alberto; Liu, Xinyue; Zhao, Xuanhe Nature communications. 27345380 2016 Jun 27;
Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells. Yang, Min; Ma, Bo; Shao, Hanshuang; Clark, Amanda M; Wells, Alan BMC cancer. 27387344 2016 Jul 07;
Phototactic guidance of a tissue-engineered soft-robotic ray. Park, Sung-Jin; Gazzola, Mattia; Park, Kyung Soo; Park, Shirley; Di Santo, Valentina; Blevins, Erin L; Lind, Johan U; Campbell, Patrick H; Dauth, Stephanie; Capulli, Andrew K; Pasqualini, Francesco S; Ahn, Seungkuk; Cho, Alexander; Yuan, Hongyan; Maoz, Be Science (New York, N.Y.). 27387948 2016 Jul 8;
Liver metastases: Microenvironments and ex-vivo models. Clark, Amanda M; Ma, Bo; Taylor, D Lansing; Griffith, Linda; Wells, Alan Experimental biology and medicine (Maywood, N.J.). 27390264 2016 Sep;
A recellularized human colon model identifies cancer driver genes. Chen, Huanhuan Joyce; Wei, Zhubo; Sun, Jian; Bhattacharya, Asmita; Savage, David J; Serda, Rita; Mackeyev, Yuri; Curley, Steven A; Bu, Pengcheng; Wang, Lihua; Chen, Shuibing; Cohen-Gould, Leona; Huang, Emina; Shen, Xiling; Lipkin, Steven M; Copeland, Neal Nature biotechnology. 27398792 2016 Aug;
Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening. Wang, Ying I; Abaci, Hasan Erbil; Shuler, Michael L Biotechnology and bioengineering. 27399645 2017 01;
Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function. Chang, Shih-Yu; Weber, Elijah J; Van Ness, Kirk P; Eaton, David L; Kelly, Edward J Clinical pharmacology and therapeutics. 27448090 2016 Jul 22;
Stress-Induced Premature Senescence of Endothelial and Endothelial Progenitor Cells. Goligorsky, M S; Hirschi, K Advances in pharmacology (San Diego, Calif.). 27451101 2016;
Attitudes and opinions regarding confirmatory adaptive clinical trials: a mixed methods analysis from the Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT) project. Meurer, William J; Legocki, Laurie; Mawocha, Samkeliso; Frederiksen, Shirley M; Guetterman, Timothy C; Barsan, William; Lewis, Roger; Berry, Donald; Fetters, Michael Trials. 27473126 2016 Jul 29;
Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins. Pattison, Amanda M; Blomain, Erik S; Merlino, Dante J; Wang, Fang; Crissey, Mary Ann S; Kraft, Crystal L; Rappaport, Jeff A; Snook, Adam E; Lynch, John P; Waldman, Scott A Infection and immunity. 27481254 2016 Oct;
Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence. Nagao, Ryan J; Xu, Jin; Luo, Ping; Xue, Jun; Wang, Yi; Kotha, Surya; Zeng, Wen; Fu, Xiaoyun; Himmelfarb, Jonathan; Zheng, Ying Tissue engineering. Part A. 27481445 2016 Aug 30;
Liver Protects Metastatic Prostate Cancer From Induced Death by Activating E-cadherin Signaling. Ma, Bo; Wheeler, Sarah E; Clark, Amanda M; Whaley, Diana L; Yang, Min; Wells, Alan Hepatology (Baltimore, Md.). 27482645 2016 Aug 2;
Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures. Lizama-Manibusan, Britney N; Klein, Sharon; McKenzie, Jennifer R; Cliffel, David E; McLaughlin, BethAnn ACS chemical neuroscience. 27504748 2016 Sep 21;
Ultrathin Polymer Membranes with Patterned, Micrometric Pores for Organs-on-Chips. Pensabene, Virginia; Costa, Lino; Terekhov, Alexander Y; Gnecco, Juan S; Wikswo, John P; Hofmeister, William H ACS applied materials & interfaces. 27513606 2016 Aug 31;
Development of a microphysiological model of human kidney proximal tubule function. Weber, Elijah J; Chapron, Alenka; Chapron, Brian D; Voellinger, Jenna L; Lidberg, Kevin A; Yeung, Catherine K; Wang, Zhican; Yamaura, Yoshiyuki; Hailey, Dale W; Neumann, Thomas; Shen, Danny D; Thummel, Kenneth E; Muczynski, Kimberly A; Himmelfarb, Jonathan; Kelly, Edward J Kidney international. 27521113 2016 Sep;
Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm. Chu, Li-Fang; Leng, Ning; Zhang, Jue; Hou, Zhonggang; Mamott, Daniel; Vereide, David T; Choi, Jeea; Kendziorski, Christina; Stewart, Ron; Thomson, James A Genome biology. 27534536 2016 Aug 17;
Human fallopian tube epithelium co-culture with murine ovarian follicles reveals crosstalk in the reproductive cycle. Zhu, Jie; Xu, Yuanming; Rashedi, Alexandra S; Pavone, Mary Ellen; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna E Molecular human reproduction. 27542947 2016 Nov;
3D microtumors in vitro supported by perfused vascular networks. Sobrino, Agua; Phan, Duc T T; Datta, Rupsa; Wang, Xiaolin; Hachey, Stephanie J; Romero-López, Mónica; Gratton, Enrico; Lee, Abraham P; George, Steven C; Hughes, Christopher C W Scientific reports. 27549930 2016 Aug 23;
Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface. Karthikeyan, Subbulakshmi; Lantvit, Daniel D; Chae, Dam Hee; Burdette, Joanna E Oncotarget. 27563818 2016 10 25;
Biomimetic on-a-chip platforms for studying cancer metastasis. Lee, Esak; Song, H-H Greco; Chen, Christopher S Current opinion in chemical engineering. 27570735 2016 Feb;
Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies. Hofer, Heidi R; Tuan, Rocky S Stem cell research & therapy. 27612948 2016 Sep 09;
Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform. Long, Thomas J; Cosgrove, Patrick A; Dunn 2nd, Robert T; Stolz, Donna B; Hamadeh, Hisham; Afshari, Cynthia; McBride, Helen; Griffith, Linda G Drug metabolism and disposition: the biological fate of chemicals. 27621203 2016 Dec;
Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics. Prasad, Bhagwat; Johnson, Katherine; Billington, Sarah; Lee, Caroline; Chung, Git W; Brown, Colin D A; Kelly, Edward J; Himmelfarb, Jonathan; Unadkat, Jashvant D Drug metabolism and disposition: the biological fate of chemicals. 27621205 2016 Dec;
Untargeted Metabolomics Strategies-Challenges and Emerging Directions. Schrimpe-Rutledge, Alexandra C; Codreanu, Simona G; Sherrod, Stacy D; McLean, John A Journal of the American Society for Mass Spectrometry. 27624161 2016 Dec;
Determination of ion mobility collision cross sections for unresolved isomeric mixtures using tandem mass spectrometry and chemometric deconvolution. Harper, Brett; Neumann, Elizabeth K; Stow, Sarah M; May, Jody C; McLean, John A; Solouki, Touradj Analytica chimica acta. 27639144 2016 Oct 05;
High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro. Shan, Jing; Logan, David J; Root, David E; Carpenter, Anne E; Bhatia, Sangeeta N Journal of biomolecular screening. 27650791 2016 Oct;
S100B and S100B autoantibody as biomarkers for early detection of brain metastases in lung cancer. Choi, Humberto; Puvenna, Vikram; Brennan, Chanda; Mahmoud, Shamseldeen; Wang, Xiao-Feng; Phillips, Michael; Janigro, Damir; Mazzone, Peter Translational lung cancer research. 27652205 2016 Aug;
Distributed and Lumped Parameter Models for the Characterization of High Throughput Bioreactors. Iannetti, Laura; D'Urso, Giovanna; Conoscenti, Gioacchino; Cutrì, Elena; Tuan, Rocky S; Raimondi, Manuela T; Gottardi, Riccardo; Zunino, Paolo PloS one. 27669413 2016;
Human mini-guts: new insights into intestinal physiology and host-pathogen interactions. In, Julie G; Foulke-Abel, Jennifer; Estes, Mary K; Zachos, Nicholas C; Kovbasnjuk, Olga; Donowitz, Mark Nature reviews. Gastroenterology & hepatology. 27677718 2016 Nov;
Tissue engineering of the heart: An evolving paradigm. Vunjak-Novakovic, Gordana The Journal of thoracic and cardiovascular surgery. 27692954 2017 03;
Organ Chips: Quality Assurance Systems in Regenerative Medicine. Pasqualini, Francesco S; Emmert, Maximillian Y; Parker, Kevin Kit; Hoerstrup, Simon P Clinical pharmacology and therapeutics. 27709615 2016 Oct 6;
Dynamic culture yields engineered myocardium with near-adult functional output. Jackman, Christopher P; Carlson, Aaron L; Bursac, Nenad Biomaterials. 27723557 2016 Dec;
Fringe instability in constrained soft elastic layers. Lin, Shaoting; Cohen, Tal; Zhang, Teng; Yuk, Hyunwoo; Abeyaratne, Rohan; Zhao, Xuanhe Soft matter. 27731462 2016 Oct 12;
Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System. Tsamandouras, N; Kostrzewski, T; Stokes, C L; Griffith, L G; Hughes, D J; Cirit, M The Journal of pharmacology and experimental therapeutics. 27760784 2017 Jan;
Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing. Lind, Johan U; Busbee, Travis A; Valentine, Alexander D; Pasqualini, Francesco S; Yuan, Hongyan; Yadid, Moran; Park, Sung-Jin; Kotikian, Arda; Nesmith, Alexander P; Campbell, Patrick H; Vlassak, Joost J; Lewis, Jennifer A; Parker, Kevin K Nature materials. 27775708 2016 Oct 24;
A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. Korthauer, Keegan D; Chu, Li-Fang; Newton, Michael A; Li, Yuan; Thomson, James; Stewart, Ron; Kendziorski, Christina Genome biology. 27782827 2016 Oct 25;
Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation. Cil, Onur; Phuan, Puay-Wah; Son, Jung-Ho; Zhu, Jie S; Ku, Colton K; Tabib, Niloufar Akhavan; Teuthorn, Andrew P; Ferrera, Loretta; Zachos, Nicholas C; Lin, Ruxian; Galietta, Luis J V; Donowitz, Mark; Kurth, Mark J; Verkman, Alan S Translational research : the journal of laboratory and clinical medicine. 27815136 2017 Apr;
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1? Production. Ceneri, Nicolle; Zhao, Lina; Young, Bryan D; Healy, Abigail; Coskun, Suleyman; Vasavada, Hema; Yarovinsky, Timur O; Ike, Kenneth; Pardi, Ruggero; Qin, Lingfen; Qin, Li; Tellides, George; Hirschi, Karen; Meadows, Judith; Soufer, Robert; Chun, Hyung J; Sade Arteriosclerosis, thrombosis, and vascular biology. 27834690 2017 Feb;
Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy. Vernetti, Lawrence A; Vogt, Andreas; Gough, Albert; Taylor, D Lansing Clinics in liver disease. 27842772 2017 02;
Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury. Leaf, Irina A; Nakagawa, Shunsaku; Johnson, Bryce G; Cha, Jin Joo; Mittelsteadt, Kristen; Guckian, Kevin M; Gomez, Ivan G; Altemeier, William A; Duffield, Jeremy S The Journal of clinical investigation. 27869651 2017 Jan 03;
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. Workman, Michael J; Mahe, Maxime M; Trisno, Stephen; Poling, Holly M; Watson, Carey L; Sundaram, Nambirajan; Chang, Ching-Fang; Schiesser, Jacqueline; Aubert, Philippe; Stanley, Edouard G; Elefanty, Andrew G; Miyaoka, Yuichiro; Mandegar, Mohammad A; Conkl Nature medicine. 27869805 2017 Jan;
Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for anti-secretory therapy of diarrheas caused by bacterial enterotoxins. Cil, Onur; Phuan, Puay-Wah; Gillespie, Anne Marie; Lee, Sujin; Tradtrantip, Lukmanee; Yin, Jianyi; Tse, Ming; Zachos, Nicholas C; Lin, Ruxian; Donowitz, Mark; Verkman, Alan S FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 27871064 2016 Nov 08;
Lipid profiling of polarized human monocyte-derived macrophages. Montenegro-Burke, J Rafael; Sutton, Jessica A; Rogers, Lisa M; Milne, Ginger L; McLean, John A; Aronoff, David M Prostaglandins & other lipid mediators. 27871801 2016 12;
A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity. Pamies, David; Barreras, Paula; Block, Katharina; Makri, Georgia; Kumar, Anupama; Wiersma, Daphne; Smirnova, Lenna; Zang, Ce; Bressler, Joseph; Christian, Kimberly M; Harris, Georgina; Ming, Guo-Li; Berlinicke, Cindy J; Kyro, Kelly; Song, Hongjun; Pardo, Carlos A; Hartung, Thomas; Hogberg, Helena T ALTEX. 27883356 2017;
Good manufacturing practice requirements for the production of tissue vitrification and warming and recovery kits for clinical research. Laronda, Monica M; McKinnon, Kelly E; Ting, Alison Y; Le Fever, Ann V; Zelinski, Mary B; Woodruff, Teresa K Journal of assisted reproduction and genetics. 27900615 ;
A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control. Coppeta, J R; Mescher, M J; Isenberg, B C; Spencer, A J; Kim, E S; Lever, A R; Mulhern, T J; Prantil-Baun, R; Comolli, J C; Borenstein, J T Lab on a chip. 27901159 ;
Improving the clinical management of traumatic brain injury through the pharmacokinetic modeling of peripheral blood biomarkers. Dadas, Aaron; Washington, Jolewis; Marchi, Nicola; Janigro, Damir Fluids and barriers of the CNS. 27903281 2016 Nov 30;
3D culture models of tissues under tension. Eyckmans, Jeroen; Chen, Christopher S Journal of cell science. 27909243 2017 Jan 01;
A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties. Clark, A M; Wheeler, S E; Young, C L; Stockdale, L; Shepard Neiman, J; Zhao, W; Stolz, D B; Venkataramanan, R; Lauffenburger, D; Griffith, L; Wells, A Lab on a chip. 27910972 2016 Dec 20;
Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease. Nakagawa, Naoki; Barron, Luke; Gomez, Ivan G; Johnson, Bryce G; Roach, Allie M; Kameoka, Sei; Jack, Richard M; Lupher Jr, Mark L; Gharib, Sina A; Duffield, Jeremy S JCI insight. 27942582 2016 Dec 08;
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit. Brown, Jacquelyn A; Codreanu, Simona G; Shi, Mingjian; Sherrod, Stacy D; Markov, Dmitry A; Neely, M Diana; Britt, Clayton M; Hoilett, Orlando S; Reiserer, Ronald S; Samson, Philip C; McCawley, Lisa J; Webb, Donna J; Bowman, Aaron B; McLean, John A; Wikswo Journal of neuroinflammation. 27955696 2016 Dec 12;
Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Hinson, J Travis; Chopra, Anant; Lowe, Andre; Sheng, Calvin C; Gupta, Rajat M; Kuppusamy, Rajarajan; O'Sullivan, John; Rowe, Glenn; Wakimoto, Hiroko; Gorham, Joshua; Zhang, Kehan; Musunuru, Kiran; Gerszten, Robert E; Wu, Sean M; Chen, Christopher S; Seidman, Jonathan G; Seidman, Christine E Cell reports. 28009297 2016 Dec 20;
Mechanotransduction and Metabolism in Cardiomyocyte Microdomains. Pasqualini, Francesco S; Nesmith, Alexander P; Horton, Renita E; Sheehy, Sean P; Parker, Kevin Kit BioMed research international. 28044126 2016;
Inhibition of ?v?5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury. McCurley, Amy; Alimperti, Stella; Campos-Bilderback, Silvia B; Sandoval, Ruben M; Calvino, Jenna E; Reynolds, Taylor L; Quigley, Catherine; Mugford, Joshua W; Polacheck, William J; Gomez, Ivan G; Dovey, Jennifer; Marsh, Graham; Huang, Angela; Qian, Fang; Weinreb, Paul H; Dolinski, Brian M; Moore, Shaun; Duffield, Jeremy S; Chen, Christopher S; Molitoris, Bruce A; Violette, Shelia M; Crackower, Michael A Journal of the American Society of Nephrology : JASN. 28062569 2017 Jun;
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection. Saxena, Kapil; Simon, Lukas M; Zeng, Xi-Lei; Blutt, Sarah E; Crawford, Sue E; Sastri, Narayan P; Karandikar, Umesh C; Ajami, Nadim J; Zachos, Nicholas C; Kovbasnjuk, Olga; Donowitz, Mark; Conner, Margaret E; Shaw, Chad A; Estes, Mary K Proceedings of the National Academy of Sciences of the United States of America. 28069942 2017 Jan 24;
Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity. Chang, Shih-Yu; Voellinger, Jenna L; Van Ness, Kirk P; Chapron, Brian; Shaffer, Rachel M; Neumann, Thomas; White, Collin C; Kavanagh, Terrance J; Kelly, Edward J; Eaton, David L Toxicology in vitro : an international journal published in association with BIBRA. 28089783 2017 Apr;
A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications. Phan, Duc T T; Wang, Xiaolin; Craver, Brianna M; Sobrino, Agua; Zhao, Da; Chen, Jerry C; Lee, Lilian Y N; George, Steven C; Lee, Abraham P; Hughes, Christopher C W Lab on a chip. 28092382 2017 01 31;
21st Century Cell Culture for 21st Century Toxicology. Pamies, David; Hartung, Thomas Chemical research in toxicology. 28092941 2017 01 17;
Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms. Shirure, V S; George, S C Lab on a chip. 28102869 2017 Feb 14;
A conceptual model for the development process of confirmatory adaptive clinical trials within an emergency research network. Mawocha, Samkeliso C; Fetters, Michael D; Legocki, Laurie J; Guetterman, Timothy C; Frederiksen, Shirley; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J Clinical trials (London, England). 28135827 2017 Jun;
A versatile platform for surface modification of microfluidic droplets. Li, Mingqiang; Jiang, Weiqian; Chen, Zaozao; Suryaprakash, Smruthi; Lv, Shixian; Tang, Zhaohui; Chen, Xuesi; Leong, Kam W Lab on a chip. 28154857 2017 Feb 14;
Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Vernetti, Lawrence; Gough, Albert; Baetz, Nicholas; Blutt, Sarah; Broughman, James R; Brown, Jacquelyn A; Foulke-Abel, Jennifer; Hasan, Nesrin; In, Julie; Kelly, Edward; Kovbasnjuk, Olga; Repper, Jonathan; Senutovitch, Nina; Stabb, Janet; Yeung, Catherine; Zachos, Nick C; Donowitz, Mark; Estes, Mary; Himmelfarb, Jonathan; Truskey, George; Wikswo, John P; Taylor, D Lansing Scientific reports. 28176881 2017 Feb 08;
Species-specific developmental timing is maintained by pluripotent stem cells ex utero. Barry, Christopher; Schmitz, Matthew T; Jiang, Peng; Schwartz, Michael P; Duffin, Bret M; Swanson, Scott; Bacher, Rhonda; Bolin, Jennifer M; Elwell, Angela L; McIntosh, Brian E; Stewart, Ron; Thomson, James A Developmental biology. 28179190 2017 Mar 15;
The molecular basis of endothelial cell plasticity. Dejana, Elisabetta; Hirschi, Karen K; Simons, Michael Nature communications. 28181491 2017 Feb 09;
The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology. Yu, Huimin; Hasan, Nesrin M; In, Julie G; Estes, Mary K; Kovbasnjuk, Olga; Zachos, Nicholas C; Donowitz, Mark Annual review of physiology. 28192061 2017 Feb 10;
Blood-brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood-central nervous system interface. Phan, Duc Tt; Bender, R Hugh F; Andrejecsk, Jillian W; Sobrino, Agua; Hachey, Stephanie J; George, Steven C; Hughes, Christopher Cw Experimental biology and medicine (Maywood, N.J.). 28195514 2017 11;
Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells. Ghosh, Chaitali; Hossain, Mohammed; Solanki, Jesal; Najm, Imad M; Marchi, Nicola; Janigro, Damir Epilepsia. 28199000 2017 Apr;
Biologically Relevant Heterogeneity: Metrics and Practical Insights. Gough, Albert; Stern, Andrew M; Maier, John; Lezon, Timothy; Shun, Tong-Ying; Chennubhotla, Chakra; Schurdak, Mark E; Haney, Steven A; Taylor, D Lansing SLAS discovery. 28231035 2017 Mar;
Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease. Roach, Tracoyia; Alcendor, Donald J Journal of neuroinflammation. 28253931 2017 Mar 03;
Laminar flow downregulates Notch activity to promote lymphatic sprouting. Choi, Dongwon; Park, Eunkyung; Jung, Eunson; Seong, Young Jin; Yoo, Jaehyuk; Lee, Esak; Hong, Mingu; Lee, Sunju; Ishida, Hiroaki; Burford, James; Peti-Peterdi, Janos; Adams, Ralf H; Srikanth, Sonal; Gwack, Yousang; Chen, Christopher S; Vogel, Hans J; Koh, Chester J; Wong, Alex K; Hong, Young-Kwon The Journal of clinical investigation. 28263185 2017 Apr 03;
Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS). Maass, Christian; Stokes, Cynthia L; Griffith, Linda G; Cirit, Murat Integrative biology : quantitative biosciences from nano to macro. 28267162 2017 Apr 18;
Biofunctionalized Plants as Diverse Biomaterials for Human Cell Culture. Fontana, Gianluca; Gershlak, Joshua; Adamski, Michal; Lee, Jae-Sung; Matsumoto, Shion; Le, Hau D; Binder, Bernard; Wirth, John; Gaudette, Glenn; Murphy, William L Advanced healthcare materials. 28319334 2017 Apr;
Doxorubicin Has Dose-Dependent Toxicity on Mouse Ovarian Follicle Development, Hormone Secretion, and Oocyte Maturation. Xiao, Shuo; Zhang, Jiyang; Liu, Mingjun; Iwahata, Hideyuki; Rogers, Hunter B; Woodruff, Teresa K Toxicological sciences : an official journal of the Society of Toxicology. 28329872 2017 06 01;
Human, Tissue-Engineered, Skeletal Muscle Myobundles to Measure Oxygen Uptake and Assess Mitochondrial Toxicity. Davis, Brittany N J; Santoso, Jeffrey W; Walker, Michaela J; Cheng, Cindy S; Koves, Timothy R; Kraus, William E; Truskey, George A Tissue engineering. Part C, Methods. 28338413 2017 04;
A Genome-wide Analysis of Human Pluripotent Stem Cell-Derived Endothelial Cells in 2D or 3D Culture. Zhang, Jue; Schwartz, Michael P; Hou, Zhonggang; Bai, Yongsheng; Ardalani, Hamisha; Swanson, Scott; Steill, John; Ruotti, Victor; Elwell, Angela; Nguyen, Bao Kim; Bolin, Jennifer; Stewart, Ron; Thomson, James A; Murphy, William L Stem cell reports. 28343999 2017 Apr 11;
A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle. Xiao, Shuo; Coppeta, Jonathan R; Rogers, Hunter B; Isenberg, Brett C; Zhu, Jie; Olalekan, Susan A; McKinnon, Kelly E; Dokic, Danijela; Rashedi, Alexandra S; Haisenleder, Daniel J; Malpani, Saurabh S; Arnold-Murray, Chanel A; Chen, Kuanwei; Jiang, Mingyang; Bai, Lu; Nguyen, Catherine T; Zhang, Jiyang; Laronda, Monica M; Hope, Thomas J; Maniar, Kruti P; Pavone, Mary Ellen; Avram, Michael J; Sefton, Elizabeth C; Getsios, Spiro; Burdette, Joanna E; Kim, J Julie; Borenstein, Jeffrey T; Woodruff, Teresa K Nature communications. 28350383 2017 Mar 28;
Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections. Zou, Winnie Y; Blutt, Sarah E; Crawford, Sue E; Ettayebi, Khalil; Zeng, Xi-Lei; Saxena, Kapil; Ramani, Sasirekha; Karandikar, Umesh C; Zachos, Nicholas C; Estes, Mary K Methods in molecular biology (Clifton, N.J.). 28361480 2017 Mar 31;
On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks. Valdez, Jorge; Cook, Christi D; Ahrens, Caroline Chopko; Wang, Alex J; Brown, Alexander; Kumar, Manu; Stockdale, Linda; Rothenberg, Daniel; Renggli, Kasper; Gordon, Elizabeth; Lauffenburger, Douglas; White, Forest; Griffith, Linda Biomaterials. 28371736 2017 Jun;
Zika Virus Infection of the Human Glomerular Cells: Implications for Viral Reservoirs and Renal Pathogenesis. Alcendor, Donald J The Journal of infectious diseases 28398522 2017 Jul 15
Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems. Lee-Montiel, Felipe T; George, Subin M; Gough, Albert H; Sharma, Anup D; Wu, Juanfang; DeBiasio, Richard; Vernetti, Lawrence A; Taylor, D Lansing Experimental biology and medicine (Maywood, N.J.). 28409533 2017 Oct;
WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue. Loskill, Peter; Sezhian, Thiagarajan; Tharp, Kevin M; Lee-Montiel, Felipe T; Jeeawoody, Shaheen; Reese, Willie Mae; Zushin, Peter-James H; Stahl, Andreas; Healy, Kevin E Lab on a chip. 28418430 2017 May 02;
A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms. Khazali, A S; Clark, A M; Wells, A Stem cell reviews. 28425064 2017 Apr 19;
JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement. Capulli, Andrew K; Emmert, Maximillian Y; Pasqualini, Francesco S; Kehl, Debora; Caliskan, Etem; Lind, Johan U; Sheehy, Sean P; Park, Sung Jin; Ahn, Seungkuk; Weber, Benedikt; Goss, Josue A; Hoerstrup, Simon P; Parker, Kevin Kit Biomaterials. 28445803 2017 Jul;
Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems. Soto-Gutierrez, Alejandro; Gough, Albert; Vernetti, Lawrence A; Taylor, D L; Monga, Satdarshan P Experimental biology and medicine (Maywood, N.J.). 28467181 2017 10;
FGF-dependent metabolic control of vascular development. Yu, Pengchun; Wilhelm, Kerstin; Dubrac, Alexandre; Tung, Joe K; Alves, Tiago C; Fang, Jennifer S; Xie, Yi; Zhu, Jie; Chen, Zehua; De Smet, Frederik; Zhang, Jiasheng; Jin, Suk-Won; Sun, Lele; Sun, Hongye; Kibbey, Richard G; Hirschi, Karen K; Hay, Nissim; Carmeliet, Peter; Chittenden, Thomas W; Eichmann, Anne; Potente, Michael; Simons, Michael Nature. 28467822 2017 05 11;
A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice. Laronda, Monica M; Rutz, Alexandra L; Xiao, Shuo; Whelan, Kelly A; Duncan, Francesca E; Roth, Eric W; Woodruff, Teresa K; Shah, Ramille N Nature communications. 28509899 2017 05 16;
Gastrointestinal microphysiological systems. Blutt, Sarah E; Broughman, James R; Zou, Winnie; Zeng, Xi-Lei; Karandikar, Umesh C; In, Julie; Zachos, Nicholas C; Kovbasnjuk, Olga; Donowitz, Mark; Estes, Mary K Experimental biology and medicine (Maywood, N.J.). 28534432 2017 10;
A Systematic Evaluation of Factors Affecting Extracellular Vesicle Uptake by Breast Cancer Cells. Stranford, Devin M; Hung, Michelle E; Gargus, Emma S; Shah, Ramille N; Leonard, Joshua N Tissue engineering. Part A. 28586292 2017 Jul 20;
Next generation human skin constructs as advanced tools for drug development. Abaci, H E; Guo, Zongyou; Doucet, Yanne; Jacków, Joanna; Christiano, Angela Experimental biology and medicine (Maywood, N.J.). 28592171 2017 11;
Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques. Barry, Christopher; Schmitz, Matthew T; Propson, Nicholas E; Hou, Zhonggang; Zhang, Jue; Nguyen, Bao K; Bolin, Jennifer M; Jiang, Peng; McIntosh, Brian E; Probasco, Mitchell D; Swanson, Scott; Stewart, Ron; Thomson, James A; Schwartz, Michael P; Murphy, William L Experimental biology and medicine (Maywood, N.J.). 28599598 2017 11;
Low levels of physiological interstitial flow eliminate morphogen gradients and guide angiogenesis. Shirure, Venktesh S; Lezia, Andrew; Tao, Arnold; Alonzo, Luis F; George, Steven C Angiogenesis. 28608153 2017 Jun 12;
Human iPS-derived endothelial cells for 3D microphysiological systems. Kurokawa, Yosuke K; Yin, Rose T; Shang, Michael R; Shirure, Venktesh S; Moya, Monica L; George, Steven C Tissue engineering. Part C, Methods. 28622076 2017 Jun 16;
3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels. Wang, Xiaolin; Phan, Duc T T; George, Steven C; Hughes, Christopher C W; Lee, Abraham P Methods in molecular biology (Clifton, N.J.). 28634954 2017;
* Extracellular Vesicles and Their Versatile Roles in Tissue Engineering. Jay, Steven M; Vunjak-Novakovic, Gordana Tissue engineering. Part A. 28649910 2017 Nov;
Integrated gut/liver microphysiological systems elucidates inflammatory inter-tissue crosstalk. Chen, Wen L K; Edington, Collin; Suter, Emily; Yu, Jiajie; Velazquez, Jeremy J; Velazquez, Jason G; Shockley, Michael; Large, Emma M; Venkataramanan, Raman; Hughes, David J; Stokes, Cynthia L; Trumper, David L; Carrier, Rebecca L; Cirit, Murat; Griffith, Linda G; Lauffenburger, Douglas A Biotechnology and bioengineering. 28667746 2017 Jul 01;
Functional characterization of human pluripotent stem cell-derived arterial endothelial cells. Zhang, Jue; Chu, Li-Fang; Hou, Zhonggang; Schwartz, Michael P; Hacker, Timothy; Vickerman, Vernella; Swanson, Scott; Leng, Ning; Nguyen, Bao Kim; Elwell, Angela; Bolin, Jennifer; Brown, Matthew E; Stewart, Ron; Burlingham, William J; Murphy, William L; Thomson, James A Proceedings of the National Academy of Sciences of the United States of America. 28696312 2017 Jul 25;
Detection of brain-directed autoantibodies in the serum of non-small cell lung cancer patients. Banjara, Manoj; Ghosh, Chaitali; Dadas, Aaron; Mazzone, Peter; Janigro, Damir PloS one. 28746384 2017;
Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies. Tsamandouras, Nikolaos; Chen, Wen Li Kelly; Edington, Collin D; Stokes, Cynthia L; Griffith, Linda G; Cirit, Murat The AAPS journal. 28752430 2017 09;
Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell-endothelial cell-regulated barrier function. Alimperti, Stella; Mirabella, Teodelinda; Bajaj, Varnica; Polacheck, William; Pirone, Dana M; Duffield, Jeremy; Eyckmans, Jeroen; Assoian, Richard K; Chen, Christopher S Proceedings of the National Academy of Sciences of the United States of America. 28765370 2017 Aug 15;
3D Differentiation of LUHMES Cell Line to Study Recovery and Delayed Neurotoxic Effects. Harris, Georgina; Hogberg, Helena; Hartung, Thomas; Smirnova, Lena Current protocols in toxicology. 28777440 2017 Aug 04;
Microphysiological Systems to Assess Nonclinical Toxicity. Van Ness, Kirk P; Chang, Shih-Yu; Weber, Elijah J; Zumpano, Danielle; Eaton, David L; Kelly, Edward J Current protocols in toxicology. 28777442 2017 Aug 04;
The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models. Gough, Albert; Vernetti, Lawrence; Bergenthal, Luke; Shun, Tong Ying; Taylor, D Lansing Applied in vitro toxicology. 28781990 2016 Jun 01;
Tissue Engineering the Vascular Tree. Traore, Mahama A; George, Steven C Tissue engineering. Part B, Reviews. 28799844 2017 12;
A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells. Atchison, Leigh; Zhang, Haoyue; Cao, Kan; Truskey, George A Scientific reports. 28811655 2017 08 15;
Myofibrils in Cardiomyocytes Tend to Assemble Along the Maximal Principle Stress Directions. Yuan, Hongyan; Marzban, Bahador; Kit Parker, Kevin Journal of biomechanical engineering 28857113 2017 Dec 01
Engineered Microvasculature in PDMS Networks Using Endothelial Cells Derived from Human Induced Pluripotent Stem Cells. Sivarapatna, Amogh; Ghaedi, Mahboobe; Xiao, Yang; Han, Edward; Aryal, Binod; Zhou, Jing; Fernandez-Hernando, Carlos; Qyang, Yibing; Hirschi, Karen K; Niklason, Laura E Cell transplantation. 28901188 2017 08;
RNA-Seq of Human Neural Progenitor Cells Exposed to Lead (Pb) Reveals Transcriptome Dynamics, Splicing Alterations and Disease Risk Associations. Jiang, Peng; Hou, Zhonggang; Bolin, Jennifer M; Thomson, James A; Stewart, Ron Toxicological sciences : an official journal of the Society of Toxicology. 28903495 2017 Sep 01;
In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4(+) T Lymphocytes. Matta, Poojitha; Sherrod, Stacy D; Marasco, Christina C; Moore, Daniel J; McLean, John A; Weitkamp, Joern-Hendrik Journal of immunology (Baltimore, Md. : 1950). 28947540 2017 Nov 01;
Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease. Cruz, Nelly M; Song, Xuewen; Czerniecki, Stefan M; Gulieva, Ramila E; Churchill, Angela J; Kim, Yong Kyun; Winston, Kosuke; Tran, Linh M; Diaz, Marco A; Fu, Hongxia; Finn, Laura S; Pei, York; Himmelfarb, Jonathan; Freedman, Benjamin S Nature materials. 28967916 2017 Nov;
Cancer-associated fibroblasts support vascular growth through mechanical force. Sewell-Loftin, Mary Kathryn; Bayer, Samantha Van Hove; Crist, Elizabeth; Hughes, Taylor; Joison, Sofia M; Longmore, Gregory D; George, Steven C Scientific reports. 28974764 2017 Oct 03;
Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening. Lind, Johan U; Yadid, Moran; Perkins, Ian; O'Connor, Blakely B; Eweje, Feyisayo; Chantre, Christophe O; Hemphill, Matthew A; Yuan, Hongyan; Campbell, Patrick H; Vlassak, Joost J; Parker, Kevin K Lab on a chip. 28976521 2017 Oct 25;
Cationic Nanocylinders Promote Angiogenic Activities of Endothelial Cells. Lee, Jung Bok; Balikov, Daniel A; Yang, Jae Won; Kim, Ki Seok; Park, Hun Kuk; Kim, Jeong Koo; Kwon, Il Keun; Bellan, Leon M; Sung, Hak-Joon Polymers. 29034114 2016 Jan;
Biomechanical regulation of drug sensitivity in an engineered model of human tumor. Marturano-Kruik, A; Villasante, A; Yaeger, K; Ambati, S R; Chramiec, A; Raimondi, M T; Vunjak-Novakovic, G Biomaterials. 29040875 2018 Jan;
MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock. Kader, Muhamuda; Alaoui-El-Azher, Mounia; Vorhauer, Jennie; Kode, Bhushan B; Wells, Jakob Z; Stolz, Donna; Michalopoulos, George; Wells, Alan; Scott, Melanie; Ismail, Nahed PLoS pathogens. 29049365 2017 Oct;
Concise Review: Current and Emerging Biomarkers of Nephrotoxicity. Weber, Elijah J; Himmelfarb, Jonathan; Kelly, Edward J Current opinion in toxicology. 29057384 2017 Jun;
Circadian hormone control in a human-on-a-chip: In vitro biology's ignored component? Cyr, Kevin J; Avaldi, Omero M; Wikswo, John P Experimental biology and medicine (Maywood, N.J.). 29065796 2017 Nov;
Self-contained, low-cost Body-on-a-Chip systems for drug development. Wang, Ying I; Oleaga, Carlota; Long, Christopher J; Esch, Mandy B; McAleer, Christopher W; Miller, Paula G; Hickman, James J; Shuler, Michael L Experimental biology and medicine (Maywood, N.J.). 29065797 2017 11;
Microphysiologic systems in female reproductive biology. Young, Alexandria N; Moyle-Heyrman, Georgette; Kim, J Julie; Burdette, Joanna E Experimental biology and medicine (Maywood, N.J.). 29065798 2017 11;
Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology. Watson, David E; Hunziker, Rosemarie; Wikswo, John P Experimental biology and medicine (Maywood, N.J.). 29065799 2017 Oct;
Application of induced pluripotent stem cells to model smooth muscle cell function in vascular diseases. Ji, HaYeun; Kim, Hye Sung; Kim, Hae-Won; Leong, Kam W Current opinion in biomedical engineering. 29082353 2017 Mar;
The life cycles of six multi-center adaptive clinical trials focused on neurological emergencies developed for the Advancing Regulatory Science initiative of the National Institutes of Health and US Food and Drug Administration: Case studies from the Adap Guetterman, Timothy C; Fetters, Michael D; Mawocha, Samkeliso; Legocki, Laurie J; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J SAGE open medicine. 29085638 2017;
Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion. Nguyen, Eric H; Daly, William T; Le, Ngoc Nhi T; Farnoodian, Mitra; Belair, David G; Schwartz, Michael P; Lebakken, Connie S; Ananiev, Gene E; Saghiri, Mohammad Ali; Knudsen, Thomas B; Sheibani, Nader; Murphy, William L Nature biomedical engineering. 29104816 2017;
Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells. Dioufa, Nikolina; Clark, Amanda M; Ma, Bo; Beckwitt, Colin H; Wells, Alan Molecular cancer. 29137633 2017 Nov 14;
Biomarker identification for statin sensitivity of cancer cell lines. Raghu, Vineet K; Beckwitt, Colin H; Warita, Katsuhiko; Wells, Alan; Benos, Panayiotis V; Oltvai, Zoltán N Biochemical and biophysical research communications. 29146185 2018 01 01;
Executive summary of the 12th HHT international scientific conference. Andrejecsk, Jillian W; Hosman, Anna E; Botella, Luisa M; Shovlin, Claire L; Arthur, Helen M; Dupuis-Girod, Sophie; Buscarini, Elisabetta; Hughes, Christopher C W; Lebrin, Franck; Mummery, Christine L; Post, Marco C; Mager, Johannes J Angiogenesis 29147802 2018 02
Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma. Villasante, A; Sakaguchi, K; Kim, J; Cheung, N K; Nakayama, M; Parsa, H; Okano, T; Shimizu, T; Vunjak-Novakovic, G Theranostics. 29158813 2017;
A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Polacheck, William J; Kutys, Matthew L; Yang, Jinling; Eyckmans, Jeroen; Wu, Yinyu; Vasavada, Hema; Hirschi, Karen K; Chen, Christopher S Nature. 29160307 2017 12 14;
Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy. Khazali, Ahmad S; Clark, Amanda M; Wells, Alan British journal of cancer. 29169181 2018 Feb 20;
Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. Chang, Shih-Yu; Weber, Elijah J; Sidorenko, Viktoriya S; Chapron, Alenka; Yeung, Catherine K; Gao, Chunying; Mao, Qingcheng; Shen, Danny; Wang, Joanne; Rosenquist, Thomas A; Dickman, Kathleen G; Neumann, Thomas; Grollman, Arthur P; Kelly, Edward J; Himmel JCI insight. 29202460 2017 Nov 16;
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Fang, Jennifer S; Coon, Brian G; Gillis, Noelle; Chen, Zehua; Qiu, Jingyao; Chittenden, Thomas W; Burt, Janis M; Schwartz, Martin A; Hirschi, Karen K Nature communications. 29247167 2017 12 15;
Liver 'organ on a chip'. Beckwitt, Colin H; Clark, Amanda M; Wheeler, Sarah; Taylor, D Lansing; Stolz, Donna B; Griffith, Linda; Wells, Alan Experimental cell research. 29291400 2018 02 01;
Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes. Jia, Shanhang; Miedel, Mark T; Ngo, Marilyn; Hessenius, Ryan; Chen, Ning; Wang, Peilu; Bahreini, Amir; Li, Zheqi; Ding, Zhijie; Shun, Tong Ying; Zuckerman, Daniel M; Taylor, D Lansing; Puhalla, Shannon L; Lee, Adrian V; Oesterreich, Steffi; Stern, Andrew M Oncology. 29306943 2018 Jan 06;
Engineering human pluripotent stem cells into a functional skeletal muscle tissue. Rao, Lingjun; Qian, Ying; Khodabukus, Alastair; Ribar, Thomas; Bursac, Nenad Nature communications. 29317646 ;
Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications. Nawroth, Janna C; Scudder, Lisa L; Halvorson, Ryan T; Tresback, Jason; Ferrier, John P; Sheehy, Sean P; Cho, Alex; Kannan, Suraj; Sunyovszki, Ilona; Goss, Josue A; Campbell, Patrick H; Parker, Kevin Kit Biofabrication. 29337695 2018 Jan 16;
A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures. Clark, Amanda M; Kumar, Manu P; Wheeler, Sarah E; Young, Carissa L; Venkataramanan, Raman; Stolz, Donna B; Griffith, Linda G; Lauffenburger, Douglas A; Wells, Alan Molecular & cellular proteomics : MCP. 29353230 2018 Apr;
Human bone perivascular niche-on-a-chip for studying metastatic colonization. Marturano-Kruik, Alessandro; Nava, Michele Maria; Yeager, Keith; Chramiec, Alan; Hao, Luke; Robinson, Samuel; Guo, Edward; Raimondi, Manuela Teresa; Vunjak-Novakovic, Gordana Proceedings of the National Academy of Sciences of the United States of America. 29363599 2018 Feb 06;
The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms. Kang, Inhae; Chu, Charleen T; Kaufman, Brett A FEBS letters. 29364506 2018 Mar;
Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues. Karolak, Aleksandra; Markov, Dmitry A; McCawley, Lisa J; Rejniak, Katarzyna A Journal of the Royal Society, Interface. 29367239 2018 Jan;
Rotenone exerts developmental neurotoxicity in a human brain spheroid model. Pamies, David; Block, Katharina; Lau, Pierre; Gribaldo, Laura; Pardo, Carlos A; Barreras, Paula; Smirnova, Lena; Wiersma, Daphne; Zhao, Liang; Harris, Georgina; Hartung, Thomas; Hogberg, Helena T Toxicology and applied pharmacology. 29428530 2018 09 01;
Multidrug Resistance Protein 1 Deficiency Promotes Doxorubicin-Induced Ovarian Toxicity in Female Mice. Wang, Yingzheng; Liu, Mingjun; Zhang, Jiyang; Liu, Yuwen; Kopp, Megan; Zheng, Weiwei; Xiao, Shuo Toxicological sciences : an official journal of the Society of Toxicology. 29462422 2018 May 01;
Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. Ronaldson-Bouchard, Kacey; Vunjak-Novakovic, Gordana Cell stem cell. 29499151 2018 03 01;
Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cells. Hoang, Plansky; Wang, Jason; Conklin, Bruce R; Healy, Kevin E; Ma, Zhen Nature protocols. 29543795 2018 Apr;
Traction force microscopy of engineered cardiac tissues. Pasqualini, Francesco Silvio; Agarwal, Ashutosh; O'Connor, Blakely Bussie; Liu, Qihan; Sheehy, Sean P; Parker, Kevin Kit PloS one. 29590169 2018;
Multifaceted Roles of Connexin 43 in Stem Cell Niches. Genet, Nafiisha; Bhatt, Neha; Bourdieu, Antonin; Hirschi, Karen K Current stem cell reports. 29600160 2018;
Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment. Kotha, Surya; Sun, Sijie; Adams, Amie; Hayes, Brian; Phong, Kiet T; Nagao, Ryan; Reems, Jo-Anna; Gao, Dayong; Torok-Storb, Beverly; López, José A; Zheng, Ying PloS one. 29617409 2018;
Advanced maturation of human cardiac tissue grown from pluripotent stem cells. Ronaldson-Bouchard, Kacey; Ma, Stephen P; Yeager, Keith; Chen, Timothy; Song, LouJin; Sirabella, Dario; Morikawa, Kumi; Teles, Diogo; Yazawa, Masayuki; Vunjak-Novakovic, Gordana Nature. 29618819 2018 Apr;
Human organoid cultures: transformative new tools for human virus studies. Ramani, Sasirekha; Crawford, Sue E; Blutt, Sarah E; Estes, Mary K Current opinion in virology. 29656244 2018 Apr;
Quantitatively characterizing drug-induced arrhythmic contractile motions of human stem cell-derived cardiomyocytes. Hoang, Plansky; Huebsch, Nathaniel; Bang, Shin Hyuk; Siemons, Brian A; Conklin, Bruce R; Healy, Kevin E; Ma, Zhen; Jacquir, Sabir Biotechnology and bioengineering. 29663322 2018 08;
Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases. Blutt, Sarah E; Crawford, Sue E; Ramani, Sasirekha; Zou, Winnie Y; Estes, Mary K Cellular and molecular gastroenterology and hepatology. 29675450 2018 Mar;
3S - Systematic, systemic, and systems biology and toxicology. Smirnova, Lena; Kleinstreuer, Nicole; Corvi, Raffaella; Levchenko, Andre; Fitzpatrick, Suzanne C; Hartung, Thomas ALTEX. 29677694 2018;
Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide. Wang, Hong-Xia; Song, Ziyuan; Lao, Yeh-Hsing; Xu, Xin; Gong, Jing; Cheng, Du; Chakraborty, Syandan; Park, Ji Sun; Li, Mingqiang; Huang, Dantong; Yin, Lichen; Cheng, Jianjun; Leong, Kam W Proceedings of the National Academy of Sciences of the United States of America. 29686087 2018 May 08;
In Vitro Tissue-Engineered Skeletal Muscle Models for Studying Muscle Physiology and Disease. Khodabukus, Alastair; Prabhu, Neel; Wang, Jason; Bursac, Nenad Advanced healthcare materials. 29696831 2018 08;
RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. Thakore, Pratiksha I; Kwon, Jennifer B; Nelson, Christopher E; Rouse, Douglas C; Gemberling, Matthew P; Oliver, Matthew L; Gersbach, Charles A Nature communications. 29700298 2018 Apr 26;
A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis. Miller, Chris P; Tsuchida, Connor; Zheng, Ying; Himmelfarb, Jonathan; Akilesh, Shreeram Neoplasia (New York, N.Y.). 29747161 2018 06;
Tissue engineering toward organ-specific regeneration and disease modeling. Mandrycky, Christian; Phong, Kiet; Zheng, Ying MRS communications. 29750131 2017 Sep;
Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling. Beckwitt, Colin H; Shiraha, Keisuke; Wells, Alan PloS one. 29763460 2018;
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping. Czerniecki, Stefan M; Cruz, Nelly M; Harder, Jennifer L; Menon, Rajasree; Annis, James; Otto, Edgar A; Gulieva, Ramila E; Islas, Laura V; Kim, Yong Kyun; Tran, Linh M; Martins, Timothy J; Pippin, Jeffrey W; Fu, Hongxia; Kretzler, Matthias; Shankland, Stuart J; Himmelfarb, Jonathan; Moon, Randall T; Paragas, Neal; Freedman, Benjamin S Cell stem cell. 29779890 2018 Jun 01;
Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies. Maass, Christian; Dallas, Matthew; LaBarge, Matthew E; Shockley, Michael; Valdez, Jorge; Geishecker, Emily; Stokes, Cynthia L; Griffith, Linda G; Cirit, Murat Scientific reports. 29789564 2018 May 22;
A pumpless body-on-a-chip model using a primary culture of human intestinal cells and a 3D culture of liver cells. Chen, Huanhuan Joyce; Miller, Paula; Shuler, Michael L Lab on a chip. 29881844 2018 07 10;
Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications. Adamski, Michal; Fontana, Gianluca; Gershlak, Joshua R; Gaudette, Glenn R; Le, Hau D; Murphy, William L Journal of visualized experiments : JoVE. 29912197 2018 05 31;
Real-time observation of leukocyte-endothelium interactions in tissue-engineered blood vessel. Chen, Z; Tang, M; Huang, D; Jiang, W; Li, M; Ji, H; Park, J; Xu, B; Atchison, L J; Truskey, G A; Leong, K W Lab on a chip. 29927449 2018 07 10;
Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers. Yin, Jianyi; Tse, Chung-Ming; Avula, Leela Rani; Singh, Varsha; Foulke-Abel, Jennifer; de Jonge, Hugo R; Donowitz, Mark Cellular and molecular gastroenterology and hepatology. 29930980 2018;
Mesangial cells, specialized renal pericytes and cytomegalovirus infectivity: Implications for HCMV pathology in the glomerular vascular unit and post-transplant renal disease. Popik, Waldemar; Correa, Hernan; Khatua, Atanu; Aronoff, David M; Alcendor, Donald J Journal of translational science. 29977613 2019 Feb;
Deep Learning for Drug Discovery and Cancer Research: Automated Analysis of Vascularization Images. Urban, Gregor; Bache, Kevin M; Phan, Duc; Sobrino, Agua; Shmakov, Alexander Konstantinovich; Hachey, Stephanie J; Hughes, Chris; Baldi, Pierre IEEE/ACM transactions on computational biology and bioinformatics. 29993583 2019 May-Jun;
Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics. Ishikawa, Takuro; Hosaka, Yoshinao Z; Beckwitt, Colin; Wells, Alan; Oltvai, Zoltán N; Warita, Katsuhiko Oncotarget. 30034619 2018 Jun 29;
A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX. Li, Xiang; George, Subin M; Vernetti, Lawrence; Gough, Albert H; Taylor, D Lansing Lab on a chip. 30063238 2018 08 21;
Production and transplantation of bioengineered lung into a large-animal model. Nichols, Joan E; La Francesca, Saverio; Niles, Jean A; Vega, Stephanie P; Argueta, Lissenya B; Frank, Luba; Christiani, David C; Pyles, Richard B; Himes, Blanca E; Zhang, Ruyang; Li, Su; Sakamoto, Jason; Rhudy, Jessica; Hendricks, Greg; Begarani, Filippo; Liu, Xuewu; Patrikeev, Igor; Pal, Rahul; Usheva, Emiliya; Vargas, Grace; Miller, Aaron; Woodson, Lee; Wacher, Adam; Grimaldo, Maria; Weaver, Daniil; Mlcak, Ron; Cortiella, Joaquin Science translational medicine. 30068570 2018 08 01;
Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics. Bajaj, Piyush; Chowdhury, Swapan K; Yucha, Robert; Kelly, Edward J; Xiao, Guangqing Drug metabolism and disposition: the biological fate of chemicals. 30076203 2018 11;
Customizable biomaterials as tools for advanced anti-angiogenic drug discovery. Nguyen, Eric H; Murphy, William L Biomaterials. 30077137 2018 10;
A system to monitor statin-induced myopathy in individual engineered skeletal muscle myobundles. Zhang, Xu; Hong, Sungmin; Yen, Ringo; Kondash, Megan; Fernandez, Cristina E; Truskey, George A Lab on a chip. 30112530 2018 09 11;
Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system. Oleaga, Carlota; Riu, Anne; Rothemund, Sandra; Lavado, Andrea; McAleer, Christopher W; Long, Christopher J; Persaud, Keisha; Narasimhan, Narasimhan Sriram; Tran, My; Roles, Jeffry; Carmona-Moran, Carlos A; Sasserath, Trevor; Elbrecht, Daniel H; Kumanchik, Lee; Bridges, L Richard; Martin, Candace; Schnepper, Mark T; Ekman, Gail; Jackson, Max; Wang, Ying I; Note, Reine; Langer, Jessica; Teissier, Silvia; Hickman, James J Biomaterials. 30130706 2018 11;
Applications of tumor chip technology. Hachey, Stephanie J; Hughes, Christopher C W Lab on a chip. 30156248 2018 09 26;
Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscle. Khodabukus, Alastair; Madden, Lauran; Prabhu, Neel K; Koves, Timothy R; Jackman, Christopher P; Muoio, Deborah M; Bursac, Nenad Biomaterials. 30180985 2019 Apr;
Human Organ-Specific Endothelial Cell Heterogeneity. Marcu, Raluca; Choi, Yoon Jung; Xue, Jun; Fortin, Chelsea L; Wang, Yuliang; Nagao, Ryan J; Xu, Jin; MacDonald, James W; Bammler, Theo K; Murry, Charles E; Muczynski, Kimberly; Stevens, Kelly R; Himmelfarb, Jonathan; Schwartz, Stephen M; Zheng, Ying iScience. 30240741 2018 Jun 29;
Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells. Liu, Bohao; Lee, Benjamin W; Nakanishi, Koki; Villasante, Aranzazu; Williamson, Rebecca; Metz, Jordan; Kim, Jinho; Kanai, Mariko; Bi, Lynn; Brown, Kristy; Di Paolo, Gilbert; Homma, Shunichi; Sims, Peter A; Topkara, Veli K; Vunjak-Novakovic, Gordana Nature biomedical engineering. 30271672 2018 May;
Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip. Sakolish, Courtney; Weber, Elijah J; Kelly, Edward J; Himmelfarb, Jonathan; Mouneimne, Roula; Grimm, Fabian A; House, John S; Wade, Terry; Han, Arum; Chiu, Weihsueh A; Rusyn, Ivan Scientific reports. 30291268 2018 10 05;
Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments. Bacher, Rhonda; Leng, Ning; Chu, Li-Fang; Ni, Zijian; Thomson, James A; Kendziorski, Christina; Stewart, Ron BMC bioinformatics. 30326833 2018 Oct 16;
A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation. Monteiro, Maria B; Ramm, Susanne; Chandrasekaran, Vidya; Boswell, Sarah A; Weber, Elijah J; Lidberg, Kevin A; Kelly, Edward J; Vaidya, Vishal S Journal of the American Society of Nephrology : JASN. 30361326 2018 12;
Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel. Hiraki, Harrison L; Nagao, Ryan J; Himmelfarb, Jonathan; Zheng, Ying Journal of visualized experiments : JoVE. 30371659 2018 10 13;
Reconstructing the Human Renal Vascular-Tubular Unit In Vitro. Rayner, Samuel G; Phong, Kiet T; Xue, Jun; Lih, Daniel; Shankland, Stuart J; Kelly, Edward J; Himmelfarb, Jonathan; Zheng, Ying Advanced healthcare materials. 30379416 2018 12;
In vitro Models of Ischemia-Reperfusion Injury. Chen, Timothy; Vunjak-Novakovic, Gordana Regenerative engineering and translational medicine. 30393757 2018 Sep;
Tumor-on-a-chip platform to investigate progression and drug sensitivity in cell lines and patient-derived organoids. Shirure, Venktesh S; Bi, Ye; Curtis, Matthew B; Lezia, Andrew; Goedegebuure, Madeleine M; Goedegebuure, S Peter; Aft, Rebecca; Fields, Ryan C; George, Steven C Lab on a chip 30393802 2018 Dec 07
Statin drugs to reduce breast cancer recurrence and mortality. Beckwitt, Colin H; Brufsky, Adam; Oltvai, Zoltán N; Wells, Alan Breast cancer research : BCR. 30458856 2018 11 20;
Cerebral Waste Accumulation and Glymphatic Clearance as Mechanisms of Human Neurological Diseases. Dadas, Aaron; Washington, Jolewis; Janigro, Damir Journal of neurology & neuromedicine 30506062 2016
Engineered 3D Microvascular Networks for the Study of Ultrasound-Microbubble-Mediated Drug Delivery. Juang, Eric K; De Cock, Ine; Keravnou, Christina; Gallagher, Madison K; Keller, Sara B; Zheng, Ying; Averkiou, Michalakis Langmuir : the ACS journal of surfaces and colloids. 30540481 2019 08 06;
Engineering a Bioartificial Human Colon Model Through Decellularization and Recellularization. Chen, Huanhuan Joyce; Shuler, Michael L Methods in molecular biology (Clifton, N.J.). 30542993 2019;
Tissue engineering of human hair follicles using a biomimetic developmental approach. Abaci, Hasan Erbil; Coffman, Abigail; Doucet, Yanne; Chen, James; Jacków, Joanna; Wang, Etienne; Guo, Zongyou; Shin, Jung U; Jahoda, Colin A; Christiano, Angela M Nature communications. 30546011 2018 12 13;
Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels. Kaushik, Gaurav; Gil, Daniel A; Torr, Elizabeth; Berge, Elizabeth S; Soref, Cheryl; Uhl, Peyton; Fontana, Gianluca; Antosiewicz-Bourget, Jessica; Edington, Collin; Schwartz, Michael P; Griffith, Linda G; Thomson, James A; Skala, Melissa C; Daly, William T; Murphy, William L Advanced healthcare materials. 30565891 2019 01;
Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity. Weber, Elijah J; Lidberg, Kevin A; Wang, Lu; Bammler, Theo K; MacDonald, James W; Li, Mavis J; Redhair, Michelle; Atkins, William M; Tran, Cecilia; Hines, Kelly M; Herron, Josi; Xu, Libin; Monteiro, Maria Beatriz; Ramm, Susanne; Vaidya, Vishal; Vaara, Martti; Vaara, Timo; Himmelfarb, Jonathan; Kelly, Edward J JCI insight. 30568031 2018 12 20;
Microfluidic device to attain high spatial and temporal control of oxygen. Lam, Sandra F; Shirure, Venktesh S; Chu, Yunli E; Soetikno, Alan G; George, Steven C PloS one. 30571786 2018;
A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis. Natividad-Diaz, Sylvia L; Browne, Shane; Jha, Amit K; Ma, Zhen; Hossainy, Samir; Kurokawa, Yosuke K; George, Steven C; Healy, Kevin E Biomaterials. 30583150 2019 Feb;
Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres. Abreu, Celina Monteiro; Gama, Lucio; Krasemann, Susanne; Chesnut, Megan; Odwin-Dacosta, Shelly; Hogberg, Helena T; Hartung, Thomas; Pamies, David Frontiers in microbiology. 30619100 2018;
A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro. Ramm, Susanne; Todorov, Petar; Chandrasekaran, Vidya; Dohlman, Anders; Monteiro, Maria B; Pavkovic, Mira; Muhlich, Jeremy; Shankaran, Harish; Chen, William W; Mettetal, Jerome T; Vaidya, Vishal S Toxicological sciences : an official journal of the Society of Toxicology. 30649541 2019 05 01;
cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity. Tse, Chung-Ming; Yin, Jianyi; Singh, Varsha; Sarker, Rafiquel; Lin, Ruxian; Verkman, Alan S; Turner, Jerrold R; Donowitz, Mark Cellular and molecular gastroenterology and hepatology. 30659943 2019;
Translational Assessment of Drug-Induced Proximal Tubule Injury Using a Kidney Microphysiological System. Maass, Christian; Sorensen, Nathan B; Himmelfarb, Jonathan; Kelly, Edward J; Stokes, Cynthia L; Cirit, Murat CPT: pharmacometrics & systems pharmacology. 30869201 2019 05;
Microfabricated blood vessels for modeling the vascular transport barrier. Polacheck, William J; Kutys, Matthew L; Tefft, Juliann B; Chen, Christopher S Nature protocols. 30953042 2019 05;
Modeling the Effect of TNF-? upon Drug-Induced Toxicity in Human, Tissue-Engineered Myobundles. Davis, Brittany N J; Santoso, Jeffrey W; Walker, Michaela J; Oliver, Catherine E; Cunningham, Michael M; Boehm, Christian A; Dawes, Danielle; Lasater, Samantha L; Huffman, Kim; Kraus, William E; Truskey, George A Annals of biomedical engineering. 30963383 2019 Jul;
A tissue-engineered scale model of the heart ventricle. MacQueen, Luke A; Sheehy, Sean P; Chantre, Christophe O; Zimmerman, John F; Pasqualini, Francesco S; Liu, Xujie; Goss, Josue A; Campbell, Patrick H; Gonzalez, Grant M; Park, Sung-Jin; Capulli, Andrew K; Ferrier, John P; Kosar, T Fettah; Mahadevan, L; Pu, William T; Parker, Kevin Kit Nature biomedical engineering. 31015723 2018 12;
Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload. Ma, Zhen; Huebsch, Nathaniel; Koo, Sangmo; Mandegar, Mohammad A; Siemons, Brian; Boggess, Steven; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin E Nature biomedical engineering. 31015724 2018 12;
A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia. Zhang, Jue; McIntosh, Brian E; Wang, Bowen; Brown, Matthew E; Probasco, Mitchell D; Webster, Sarah; Duffin, Bret; Zhou, Ying; Guo, Lian-Wang; Burlingham, William J; Kent, Craig; Ferris, Michael; Thomson, James A Stem cell reports. 31080110 2019 Jun 11;
Adult Stem Cell Functioning in the Tumor Micro-Environment. Jiang, Yuhan; Wells, Alan; Sylakowski, Kyle; Clark, Amanda M; Ma, Bo International journal of molecular sciences 31130595 2019 May 25
Oxygen consumption in human, tissue-engineered myobundles during basal and electrical stimulation conditions. Davis, Brittany N; Yen, Ringo; Prasad, Varun; Truskey, George A APL bioengineering. 31149650 2019 Jun;
Insights Into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia From Engineered Human Heart Tissue. Park, Sung-Jin; Zhang, Donghui; Qi, Yan; Li, Yifei; Lee, Keel Yong; Bezzerides, Vassilios J; Yang, Pengcheng; Xia, Shutao; Kim, Sean L; Liu, Xujie; Lu, Fujian; Pasqualini, Francesco S; Campbell, Patrick H; Geva, Judith; Roberts, Amy E; Kleber, Andre G; Abrams, Dominic J; Pu, William T; Parker, Kevin Kit Circulation. 31311300 2019 Jul 30;
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Argemi, Josepmaria; Latasa, Maria U; Atkinson, Stephen R; Blokhin, Ilya O; Massey, Veronica; Gue, Joel P; Cabezas, Joaquin; Lozano, Juan J; Van Booven, Derek; Bell, Aaron; Cao, Sheng; Vernetti, Lawrence A; Arab, Juan P; Ventura-Cots, Meritxell; Edmunds, Lia R; Fondevilla, Constantino; Stärkel, Peter; Dubuquoy, Laurent; Louvet, Alexandre; Odena, Gemma; Gomez, Juan L; Aragon, Tomas; Altamirano, Jose; Caballeria, Juan; Jurczak, Michael J; Taylor, D Lansing; Berasain, Carmen; Wahlestedt, Claes; Monga, Satdarshan P; Morgan, Marsha Y; Sancho-Bru, Pau; Mathurin, Philippe; Furuya, Shinji; Lackner, Carolin; Rusyn, Ivan; Shah, Vijay H; Thursz, Mark R; Mann, Jelena; Avila, Matias A; Bataller, Ramon Nature communications. 31311938 2019 Jul 16;
The pan-therapeutic resistance of disseminated tumor cells: Role of phenotypic plasticity and the metastatic microenvironment. Ma, Bo; Wells, Alan; Clark, Amanda M Seminars in cancer biology. 31376430 2019 Jul 31;
Engineered skeletal muscles for disease modeling and drug discovery. Wang, Jason; Khodabukus, Alastair; Rao, Lingjun; Vandusen, Keith; Abutaleb, Nadia; Bursac, Nenad Biomaterials. 31419653 2019 Nov;
An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells. Chu, Li-Fang; Mamott, Daniel; Ni, Zijian; Bacher, Rhonda; Liu, Cathy; Swanson, Scott; Kendziorski, Christina; Stewart, Ron; Thomson, James A Cell reports. 31461642 2019 Aug 27;
A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling. Nguyen, Duc-Huy T; Lee, Esak; Alimperti, Styliani; Norgard, Robert J; Wong, Alec; Lee, Jake June-Koo; Eyckmans, Jeroen; Stanger, Ben Z; Chen, Christopher S Science advances. 31489365 2019 Aug;
Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype. Ronaldson-Bouchard, Kacey; Yeager, Keith; Teles, Diogo; Chen, Timothy; Ma, Stephen; Song, LouJin; Morikawa, Kumi; Wobma, Holly M; Vasciaveo, Alessandro; Ruiz, Edward C; Yazawa, Masayuki; Vunjak-Novakovic, Gordana Nature protocols. 31492957 2019 10;
Endothelial Cell Development and Its Application to Regenerative Medicine. Qiu, Jingyao; Hirschi, Karen K Circulation research 31518171 2019 08 02
Lessons from the Established Status Epilepticus Treatment Trial. Cock, Hannah R; Coles, Lisa D; Elm, Jordan; Silbergleit, Robert; Chamberlain, James M; Cloyd, James C; Fountain, Nathan; Shinnar, Shlomo; Lowenstein, Dan; Conwit, Robin; Bleck, Thomas P; Kapur, Jaideep Epilepsy & behavior : E&B. 31653603 2019 Dec;
Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence. Garbern, Jessica C; Helman, Aharon; Sereda, Rebecca; Sarikhani, Mohsen; Ahmed, Aishah; Escalante, Gabriela O; Ogurlu, Roza; Kim, Sean L; Zimmerman, John F; Cho, Alexander; MacQueen, Luke; Bezzerides, Vassilios J; Parker, Kevin Kit; Melton, Douglas A; Lee, Circulation. 31707831 2020 01 28;
Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus. Kapur, Jaideep; Elm, Jordan; Chamberlain, James M; Barsan, William; Cloyd, James; Lowenstein, Daniel; Shinnar, Shlomo; Conwit, Robin; Meinzer, Caitlyn; Cock, Hannah; Fountain, Nathan; Connor, Jason T; Silbergleit, Robert; NETT and PECARN Investigators The New England journal of medicine. 31774955 2019 11 28;
Human Induced Pluripotent Stem-Cardiac-Endothelial-Tumor-on-a-Chip to Assess Anticancer Efficacy and Cardiotoxicity. Weng, Kuo-Chan; Kurokawa, Yosuke K; Hajek, Brianna S; Paladin, Jack A; Shirure, Venktesh S; George, Steven C Tissue engineering. Part C, Methods. 31797733 2020 Jan;
Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics. Barry, Christopher; Schmitz, Matthew T; Argus, Cara; Bolin, Jennifer M; Probasco, Mitchell D; Leng, Ning; Duffin, Bret M; Steill, John; Swanson, Scott; McIntosh, Brian E; Stewart, Ron; Kendziorski, Christina; Thomson, James A; Bacher, Rhonda PLoS computational biology. 31815944 2019 12;
Expression of E-cadherin and specific CXCR3 isoforms impact each other in prostate cancer. Ma, Bo; Khazali, Ahmad; Shao, Hanshuang; Jiang, Yuhan; Wells, Alan Cell communication and signaling : CCS. 31831069 2019 Dec 12;
Predicting tubular reabsorption with a human kidney proximal tubule tissue-on-a-chip and physiologically-based modeling. Sakolish, Courtney; Chen, Zunwei; Dalaijamts, Chimeddulam; Mitra, Kusumica; Liu, Yina; Fulton, Tracy; Wade, Terry L; Kelly, Edward J; Rusyn, Ivan; Chiu, Weihsueh A Toxicology in vitro : an international journal published in association with BIBRA. 31857146 2020 Mar;
Perspectives on In Vitro to In Vivo Extrapolations. Hartung, Thomas Applied in vitro toxicology. 31890748 2018 Dec 01;
Maladaptive Contractility of 3D Human Cardiac Microtissues to Mechanical Nonuniformity. Wang, Chenyan; Koo, Sangmo; Park, Minok; Vangelatos, Zacharias; Hoang, Plansky; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin E; Ma, Zhen Advanced healthcare materials. 32090507 2020 Apr;
TimeMeter assesses temporal gene expression similarity and identifies differentially progressing genes. Jiang, Peng; Chamberlain, Connie S; Vanderby, Ray; Thomson, James A; Stewart, Ron Nucleic acids research. 32123905 2020 05 21;
Machine learning to predict developmental neurotoxicity with high-throughput data from 2D bio-engineered tissues. Kuusisto, Finn; Costa, Vitor Santos; Hou, Zhonggang; Thomson, James; Page, David; Stewart, Ron Proceedings of the ... International Conference on Machine Learning and Applications. International Conference on Machine Learning and Applications. 32181450 2019 Dec;
Glucose Uptake and Insulin Response in Tissue-engineered Human Skeletal Muscle. Kondash, Megan E; Ananthakumar, Anandita; Khodabukus, Alastair; Bursac, Nenad; Truskey, George A Tissue engineering and regenerative medicine. 32200516 2020 Mar 21;
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial. Chamberlain, James M; Kapur, Jaideep; Shinnar, Shlomo; Elm, Jordan; Holsti, Maija; Babcock, Lynn; Rogers, Alex; Barsan, William; Cloyd, James; Lowenstein, Daniel; Bleck, Thomas P; Conwit, Robin; Meinzer, Caitlyn; Cock, Hannah; Fountain, Nathan B; Underwoo Lancet (London, England). 32203691 2020 04 11;
Applications of the microphysiology systems database for experimental ADME-Tox and disease models. Schurdak, Mark; Vernetti, Lawrence; Bergenthal, Luke; Wolter, Quinn K; Shun, Tong Ying; Karcher, Sandra; Taylor, D Lansing; Gough, Albert Lab on a chip. 32211684 2020 Apr 14;
Engineered reproductive tissues. Gargus, Emma S; Rogers, Hunter B; McKinnon, Kelly E; Edmonds, Maxwell E; Woodruff, Teresa K Nature biomedical engineering. 32251392 2020 04;
Oligoproline-derived nanocarrier for dual stimuli-responsive gene delivery. Gupta, Mukesh K; Lee, Sue Hyun; Crowder, Spencer W; Wang, Xintong; Hofmeister, Lucas H; Nelson, Christopher E; Bellan, Leon M; Duvall, Craig L; Sung, Hak-Joon Journal of materials chemistry. B 32262835 2015 Sep 28
Tissue-Engineered Human Myobundle System as a Platform for Evaluation of Skeletal Muscle Injury Biomarkers. Khodabukus, Alastair; Kaza, Amulya; Wang, Jason; Prabhu, Neel; Goldstein, Richard; Vaidya, Vishal S; Bursac, Nenad Toxicological sciences : an official journal of the Society of Toxicology. 32294208 2020 Jul 01;
Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection. Foulke-Abel, Jennifer; Yu, Huimin; Sunuwar, Laxmi; Lin, Ruxian; Fleckenstein, James M; Kaper, James B; Donowitz, Mark Gut microbes. 32378997 2020 May 07;
Testicular organoid formation is a property of immature somatic cells, which self-assemble and exhibit long-term hormone-responsive endocrine function. Edmonds, Maxwell E; Woodruff, Teresa K Biofabrication. 32492667 2020 07 09;
Integrative microphysiological tissue systems of cancer metastasis to the liver. Clark, Amanda M; Allbritton, Nancy L; Wells, Alan Seminars in cancer biology. 32580025 2020 Jun 21;
Distinct follicular and luteal transcriptional profiles in engineered human ectocervical tissue dependent on menstrual cycle phase. McKinnon, Kelly E; Getsios, Spiro; Woodruff, Teresa K Biology of reproduction 32614039 2020 08 21
Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes. Bhatraju, Pavan K; Cohen, Max; Nagao, Ryan J; Morrell, Eric D; Kosamo, Susanna; Chai, Xin-Ya; Nance, Robin; Dmyterko, Victoria; Delaney, Joseph; Christie, Jason D; Liu, Kathleen D; Mikacenic, Carmen; Gharib, Sina A; Liles, W Conrad; Zheng, Ying; Christiani, David C; Himmelfarb, Jonathan; Wurfel, Mark M BMC nephrology 32680471 2020 07 17
Continuous Formation of Ultrathin, Strong Collagen Sheets with Tunable Anisotropy and Compaction. Malladi, Shashi; Miranda-Nieves, David; Leng, Lian; Grainger, Stephanie J; Tarabanis, Constantine; Nesmith, Alexander P; Kosaraju, Revanth; Haller, Carolyn A; Parker, Kevin Kit; Chaikof, Elliot L; Günther, Axel ACS biomaterials science & engineering 32685675 2020 07 13
A functional long-term 2D serum-free human hepatic in vitro system for drug evaluation. Oleaga, Carlota; Bridges, L Richard; Persaud, Keisha; McAleer, Christopher W; Long, Christopher J; Hickman, James J Biotechnology progress 32829524 2021 01
Microphysiological system modeling of ochratoxin A-associated nephrotoxicity. Imaoka, Tomoki; Yang, Jade; Wang, Lu; McDonald, Matthew G; Afsharinejad, Zahra; Bammler, Theo K; Van Ness, Kirk; Yeung, Catherine K; Rettie, Allan E; Himmelfarb, Jonathan; Kelly, Edward J Toxicology 32905824 2020 11
Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety. Chramiec, Alan; Teles, Diogo; Yeager, Keith; Marturano-Kruik, Alessandro; Pak, Joseph; Chen, Timothy; Hao, Luke; Wang, Miranda; Lock, Roberta; Tavakol, Daniel Naveed; Lee, Marcus Busub; Kim, Jinho; Ronaldson-Bouchard, Kacey; Vunjak-Novakovic, Gordana Lab on a chip 32955072 2020 11 24
Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs. Liu, Yizhong; Sakolish, Courtney; Chen, Zunwei; Phan, Duc T T; Bender, R Hugh F; Hughes, Christopher C W; Rusyn, Ivan Toxicology. 32980478 2020 Dec 01;
Isolation of Highly Purified and Viable Retinal Endothelial Cells. Chavkin, Nicholas W; Walsh, Kenneth; Hirschi, Karen K Journal of vascular research 33022674 2021
A Perspective on Therapeutic Pan-Resistance in Metastatic Cancer. Korentzelos, Dimitrios; Clark, Amanda M; Wells, Alan International journal of molecular sciences. 33022920 2020 Oct 03;
Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip. Yadid, Moran; Lind, Johan U; Ardoña, Herdeline Ann M; Sheehy, Sean P; Dickinson, Lauren E; Eweje, Feyisayo; Bastings, Maartje M C; Pope, Benjamin; O'Connor, Blakely B; Straubhaar, Juerg R; Budnik, Bogdan; Kleber, Andre G; Parker, Kevin Kit Science translational medicine 33055246 2020 10 14
Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip. Yin, Jianyi; Sunuwar, Laxmi; Kasendra, Magdalena; Yu, Huimin; Tse, Chung-Ming; Talbot Jr, C Conover; Boronina, Tatiana; Cole, Robert; Karalis, Katia; Donowitz, Mark American journal of physiology. Gastrointestinal and liver physiology 33074011 2021 03 01
Extra Cellular Matrix-Based and Extra Cellular Matrix-Free Generation of Murine Testicular Organoids. Edmonds, Maxwell E; Forshee, Micah D; Woodruff, Teresa K Journal of visualized experiments : JoVE. 33104061 2020 10 07;
Modeling statin myopathy in a human skeletal muscle microphysiological system. Ananthakumar, Anandita; Liu, Yiling; Fernandez, Cristina E; Truskey, George A; Voora, Deepak PloS one 33237943 2020
Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification. Qiu, Jingyao; Nordling, Sofia; Vasavada, Hema H; Butcher, Eugene C; Hirschi, Karen K Cell reports 33264627 2020 Dec 01
Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS). Sakolish, Courtney; Reese, Celeste E; Luo, Yu-Syuan; Valdiviezo, Alan; Schurdak, Mark E; Gough, Albert; Taylor, D Lansing; Chiu, Weihsueh A; Vernetti, Lawrence A; Rusyn, Ivan Toxicology 33307106 2021 01 30
Electroencephalographic Seizures in Emergency Department Patients After Treatment for Convulsive Status Epilepticus. Zehtabchi, Shahriar; Silbergleit, Robert; Chamberlain, James M; Shinnar, Shlomo; Elm, Jordan J; Underwood, Ellen; Rosenthal, Eric S; Bleck, Thomas P; Kapur, Jaideep Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 33337664 2020 Dec 11
Modeling the Complexity of the Metastatic Niche Ex Vivo. Clark, Amanda M Methods in molecular biology (Clifton, N.J.) 33340364 2021
A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®. Bircsak, Kristin M; DeBiasio, Richard; Miedel, Mark; Alsebahi, Alaa; Reddinger, Ryan; Saleh, Anthony; Shun, Tongying; Vernetti, Lawrence A; Gough, Albert Toxicology 33359578 2021 Feb 28
An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy. Hachey, Stephanie J; Movsesyan, Silva; Nguyen, Quy H; Burton-Sojo, Giselle; Tankazyan, Ani; Wu, Jie; Hoang, Tuyen; Zhao, Da; Wang, Shuxiong; Hatch, Michaela M; Celaya, Elizabeth; Gomez, Samantha; Chen, George T; Davis, Ryan T; Nee, Kevin; Pervolarakis, Nicholas; Lawson, Devon A; Kessenbrock, Kai; Lee, Abraham P; Lowengrub, John; Waterman, Marian L; Hughes, Christopher C W Lab on a chip 33605955 2021 04 07
Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues. Song, H-H Greco; Lammers, Alex; Sundaram, Subramanian; Rubio, Logan; Chen, Amanda X; Li, Linqing; Eyckmans, Jeroen; Bhatia, Sangeeta N; Chen, Christopher S Advanced functional materials 33613149 2020 Nov 25
Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease. Lidberg, Kevin A; Annalora, Andrew J; Jozic, Marija; Elson, Daniel J; Wang, Lu; Bammler, Theo K; Ramm, Susanne; Monteiro, Maria Beatriz; Himmelfarb, Jonathan; Marcus, Craig B; Iversen, Patrick L; Kelly, Edward J Scientific reports 33633318 2021 Feb 25
Interspecies chimeric conditions affect the developmental rate of human pluripotent stem cells. Brown, Jared; Barry, Christopher; Schmitz, Matthew T; Argus, Cara; Bolin, Jennifer M; Schwartz, Michael P; Van Aartsen, Amy; Steill, John; Swanson, Scott; Stewart, Ron; Thomson, James A; Kendziorski, Christina PLoS computational biology 33647016 2021 03
Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling. Mina, Sara G; Alaybeyoglu, Begum; Murphy, William L; Thomson, James A; Stokes, Cynthia L; Cirit, Murat Frontiers in big data 33693346 2019
Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers. Chen, Amanda X; Chhabra, Arnav; Song, H-H Greco; Fleming, Heather E; Chen, Christopher S; Bhatia, Sangeeta N Advanced functional materials 33776613 2020 Nov 25
Vascular endothelial cell specification in health and disease. Marziano, Corina; Genet, Gael; Hirschi, Karen K Angiogenesis 33844116 2021 Apr 12
Directed Differentiation of Hemogenic Endothelial Cells from Human Pluripotent Stem Cells. Nelson, Elizabeth A; Qiu, Jingyao; Chavkin, Nicholas W; Hirschi, Karen K Journal of visualized experiments : JoVE 33871448 2021 03 31
Early Neurologic Recovery, Practice Pattern Variation, and the Risk of Endotracheal Intubation Following Established Status Epilepticus. Rosenthal, Eric S; Elm, Jordan J; Ingles, James; Rogers, Alexander J; Terndrup, Thomas E; Holsti, Maija; Thomas, Danny G; Babcock, Lynn; Okada, Pamela J; Lipsky, Robert H; Miller, Joseph B; Hickey, Robert W; Barra, Megan E; Bleck, Thomas P; Cloyd, James C; Silbergleit, Robert; Lowenstein, Daniel H; Coles, Lisa D; Kapur, Jaideep; Shinnar, Shlomo; Chamberlain, James M; Established Status Epilepticus Treatment Trial Study Group Neurology 34032604 2021 05 11
Platforms to test the temporospatial capabilities of carrier systems in delivering growth factors to benefit vascular bioengineering. Argueta, Lissenya B; Niles, Jean A; Sakamoto, Jason; Liu, Xuewu; Vega, Stephanie P; Frank, Luba; Paessler, Marco; Cortiella, Joaquin; Nichols, Joan E Nanomedicine : nanotechnology, biology, and medicine 34147665 2021 08
The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation. Chavkin, Nicholas W; Sano, Soichi; Wang, Ying; Oshima, Kosei; Ogawa, Hayato; Horitani, Keita; Sano, Miho; MacLauchlan, Susan; Nelson, Anders; Setia, Karishma; Vippa, Tanvi; Watanabe, Yosuke; Saucerman, Jeffrey J; Hirschi, Karen K; Gokce, Noyan; Walsh, Kenneth Journal of the American Heart Association 34155901 2021 07 06
Non-destructive vacuum-assisted measurement of lung elastic modulus. Chen, Jiawen; Mir, Seyed Mohammad; Pinezich, Meghan R; O'Neill, John D; Guenthart, Brandon A; Bacchetta, Matthew; Vunjak-Novakovic, Gordana; Huang, Sarah X L; Kim, Jinho Acta biomaterialia 34192570 2021 Sep 01
A High-Throughput Mechanical Activator for Cartilage Engineering Enables Rapid Screening of in vitro Response of Tissue Models to Physiological and Supra-Physiological Loads. Capuana, Elisa; Marino, Davide; Di Gesù, Roberto; La Carrubba, Vincenzo; Brucato, Valerio; Tuan, Rocky S; Gottardi, Riccardo Cells, tissues, organs 34261061 2022
Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation. Blutt, Sarah E; Crawford, Sue E; Bomidi, Carolyn; Zeng, Xi-Lei; Broughman, James R; Robertson, Matthew; Coarfa, Cristian; Tessier, Mary Elizabeth M; Savidge, Tor; Hollinger, F Blaine; Curley, Steven A; Donowitz, Mark; Estes, Mary K American journal of physiology. Gastrointestinal and liver physiology 34288725 2021 09 01
The vascular niche in next generation microphysiological systems. Ewald, Makena L; Chen, Yu-Hsi; Lee, Abraham P; Hughes, Christopher C W Lab on a chip 34396383 2021 09 07
High resolution stereolithography fabrication of perfusable scaffolds to enable long-term meso-scale hepatic culture for disease modeling. Sphabmixay, Pierre; Raredon, Micha Sam Brickman; Wang, Alex J-S; Lee, Howon; Hammond, Paula T; Fang, Nicholas X; Griffith, Linda G Biofabrication 34479229 2021 09 21
Understanding neural stem cell regulation in vivo and applying the insights to cell therapy for strokes. Genet, Nafiisha; Hirschi, Karen K Regenerative medicine 34498495 2021 09
A Mesoscale 3D Culture System for Native and Engineered Biphasic Tissues: Application to the Osteochondral Unit. Chiesa, Irene; Di Gesù, Roberto; Overholt, Kalon J; Gottardi, Riccardo Methods in molecular biology (Clifton, N.J.) 34520018 2022
Prediction of hepatic drug clearance with a human microfluidic four-cell liver acinus microphysiology system. Sakolish, Courtney; Luo, Yu-Syuan; Valdiviezo, Alan; Vernetti, Lawrence A; Rusyn, Ivan; Chiu, Weihsueh A Toxicology 34543702 2021 Nov
milliPillar: A Platform for the Generation and Real-Time Assessment of Human Engineered Cardiac Tissues. Tamargo, Manuel Alejandro; Nash, Trevor Ray; Fleischer, Sharon; Kim, Youngbin; Vila, Olaia Fernandez; Yeager, Keith; Summers, Max; Zhao, Yimu; Lock, Roberta; Chavez, Miguel; Costa, Troy; Vunjak-Novakovic, Gordana ACS biomaterials science & engineering 34668692 2021 11 08
Aquaporin 9 induction in human iPSC-derived hepatocytes facilitates modeling of ornithine transcarbamylase deficiency. Laemmle, Alexander; Poms, Martin; Hsu, Bernadette; Borsuk, Mariia; Rüfenacht, Véronique; Robinson, Joshua; Sadowski, Martin C; Nuoffer, Jean-Marc; Häberle, Johannes; Willenbring, Holger Hepatology (Baltimore, Md.) 34786702 2021 Nov 16
Organ-on-a-chip model of vascularized human bone marrow niches. Glaser, Drew E; Curtis, Matthew B; Sariano, Peter A; Rollins, Zachary A; Shergill, Bhupinder S; Anand, Aravind; Deely, Alyssa M; Shirure, Venktesh S; Anderson, Leif; Lowen, Jeremy M; Ng, Natalie R; Weilbaecher, Katherine; Link, Daniel C; George, Steven C Biomaterials 34810038 2022 01
Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Eicher, Alexandra K; Kechele, Daniel O; Sundaram, Nambirajan; Berns, H Matthew; Poling, Holly M; Haines, Lauren E; Sanchez, J Guillermo; Kishimoto, Keishi; Krishnamurthy, Mansa; Han, Lu; Zorn, Aaron M; Helmrath, Michael A; Wells, James M Cell stem cell 34856121 2022 01 06
Cyclosporine Induces Fenestra-Associated Injury in Human Renal Microvessels In Vitro. Nagao, Ryan J; Marcu, Raluca; Shin, Yu Jung; Lih, Daniel; Xue, Jun; Arang, Nadia; Wei, Ling; Akilesh, Shreeram; Kaushansky, Alexis; Himmelfarb, Jonathan; Zheng, Ying ACS biomaterials science & engineering 34927415 2022 01 10
Network inference with Granger causality ensembles on single-cell transcriptomics. Deshpande, Atul; Chu, Li-Fang; Stewart, Ron; Gitter, Anthony Cell reports 35139376 2022 02 08
An autonomously swimming biohybrid fish designed with human cardiac biophysics. Lee, Keel Yong; Park, Sung-Jin; Matthews, David G; Kim, Sean L; Marquez, Carlos Antonio; Zimmerman, John F; Ardoña, Herdeline Ann M; Kleber, Andre G; Lauder, George V; Parker, Kevin Kit Science (New York, N.Y.) 35143298 2022 02 11
Endothelial Cell Differentiation and Hemogenic Specification. Aragon, Jordon W; Hirschi, Karen K Cold Spring Harbor perspectives in medicine 35193895 2022 07 29
Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity. Pamies, David; Wiersma, Daphne; Katt, Moriah E; Zhao, Liang; Burtscher, Johannes; Harris, Georgina; Smirnova, Lena; Searson, Peter C; Hartung, Thomas; Hogberg, Helena T Neurobiology of disease 35398340 2022 07
Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia. Cruz, Nelly M; Reddy, Raghava; McFaline-Figueroa, José L; Tran, Christine; Fu, Hongxia; Freedman, Benjamin S Nature biomedical engineering 35478224 2022 04
Kidney microphysiological models for nephrotoxicity assessment. Mahadeo, Anish; Yeung, Catherine K; Himmelfarb, Jonathan; Kelly, Edward J Current opinion in toxicology 35495549 2022 Jun
Comparison of Bayesian vs Frequentist Adaptive Trial Design in the Stroke Hyperglycemia Insulin Network Effort Trial. Broglio, Kristine; Meurer, William J; Durkalski, Valerie; Pauls, Qi; Connor, Jason; Berry, Donald; Lewis, Roger J; Johnston, Karen C; Barsan, William G JAMA network open 35544137 2022 05 02
A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models. Singh, Dharaminder; Deosarkar, Sudhir P; Cadogan, Elaine; Flemington, Vikki; Bray, Alysha; Zhang, Jingwen; Reiserer, Ronald S; Schaffer, David K; Gerken, Gregory B; Britt, Clayton M; Werner, Erik M; Gibbons, Francis D; Kostrzewski, Tomasz; Chambers, Chris PLoS biology 35617197 2022 05
A vascularized model of the human liver mimics regenerative responses. Chhabra, Arnav; Song, H-H Greco; Grzelak, Katarzyna A; Polacheck, William J; Fleming, Heather E; Chen, Christopher S; Bhatia, Sangeeta N Proceedings of the National Academy of Sciences of the United States of America 35763565 2022 Jul 12
Recreating the heart's helical structure-function relationship with focused rotary jet spinning. Chang, Huibin; Liu, Qihan; Zimmerman, John F; Lee, Keel Yong; Jin, Qianru; Peters, Michael M; Rosnach, Michael; Choi, Suji; Kim, Sean L; Ardoña, Herdeline Ann M; MacQueen, Luke A; Chantre, Christophe O; Motta, Sarah E; Cordoves, Elizabeth M; Parker, Kevin Science (New York, N.Y.) 35857545 2022 07 08
Engineering Modular 3D Liver Culture Microenvironments In Vitro to Parse the Interplay between Biophysical and Biochemical Microenvironment Cues on Hepatic Phenotypes. Wang, Alex J; Allen, Allysa; Sofman, Marianna; Sphabmixay, Pierre; Yildiz, Ece; Griffith, Linda G Advanced nanobiomed research 35872804 2022 Jan
Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease. Li, Sienna R; Gulieva, Ramila E; Helms, Louisa; Cruz, Nelly M; Vincent, Thomas; Fu, Hongxia; Himmelfarb, Jonathan; Freedman, Benjamin S Nature communications 36564419 2022 Dec 23
Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome. Abutaleb, Nadia O; Atchison, Leigh; Choi, Leandro; Bedapudi, Akhil; Shores, Kevin; Gete, Yantenew; Cao, Kan; Truskey, George A Scientific reports 36977745 2023 Mar 28
Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone. Genet, Nafiisha; Genet, Gael; Chavkin, Nicholas W; Paila, Umadevi; Fang, Jennifer S; Vasavada, Hema H; Goldberg, Joshua S; Acharya, Bipul R; Bhatt, Neha S; Baker, Kasey; McDonnell, Stephanie P; Huba, Mahalia; Sankaranarayanan, Danya; Ma, Gerry Z M; Eichmann, Anne; Thomas, Jean-Leon; Ffrench-Constant, Charles; Hirschi, Karen K Cell reports 37043357 2023 Apr 25
Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice. Kam, Chen Yuan; Singh, Ishani D; Gonzalez, David G; Matte-Martone, Catherine; Solá, Paloma; Solanas, Guiomar; Bonjoch, Júlia; Marsh, Edward; Hirschi, Karen K; Greco, Valentina Cell 37167971 2023 May 25
MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis. Wu, Yinyu; Paila, Umadevi; Genet, Gael; Hirschi, Karen K Developmental cell 37295435 2023 Jul 24
One transgene, two myopathies: an MTM1 'cross gene therapy' for BIN1 deficiency? Asgarian, Zeinab; Siam, Ala'a; Counsell, John R Brain : a journal of neurology 37738144 2023 Oct 03
Emulator-based Bayesian inference on non-proportional scintillation models by compton-edge probing. Breitenmoser, David; Cerutti, Francesco; Butterweck, Gernot; Kasprzak, Malgorzata Magdalena; Mayer, Sabine Nature communications 38012127 2023 Nov 28

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