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The search results on this publication page are automated on a monthly schedule based on acknowledgment of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
Transformative High Resolution Cryo-Electron Microscopy (187)
| Publication Title | Authors | Journal | Publication Date | Page No | PubMedID |
|---|---|---|---|---|---|
| Batch Production of High-Quality Graphene Grids for Cryo-EM: Cryo-EM Structure of Methylococcus capsulatus Soluble Methane Monooxygenase Hydroxylase. | Ahn, Eungjin; Kim, Byungchul; Park, Soyoung; Erwin, Amanda L; Sung, Suk Hyun; Hovden, Robert; Mosalaganti, Shyamal; Cho, Uhn-Soo | ACS nano | 2023 Mar 28 | 6011-6022 | 36926824 |
| rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. | Sekulski, Kamil; Cruz, Victor Emmanuel; Weirich, Christine S; Erzberger, Jan P | Nature communications | 2023 Mar 02 | 1207 | 36864048 |
| Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. | Fan, Minrui; Zhang, Jianxiu; Lee, Chien-Ling; Zhang, Jinru; Feng, Liang | Nature | 2023 Feb | 788-793 | 36792826 |
| Lysate-to-grid: Rapid Isolation of Native Complexes from Budding Yeast for Cryo-EM Imaging. | Cooney, Ian; Mack, Deirdre C; Ferrell, Aaron J; Stewart, Michael G; Wang, Shuxin; Donelick, Helen M; Tamayo-Jaramillo, Daniela; Greer, Dakota L; Zhu, Danyang; Li, Wenyan; Shen, Peter S | Bio-protocol | 2023 Jan 20 | 36789166 | |
| Cross-protective antibodies against common endemic respiratory viruses. | Cabán, Madelyn; Rodarte, Justas V; Bibby, Madeleine; Gray, Matthew D; Taylor, Justin J; Pancera, Marie; Boonyaratanakornkit, Jim | Nature communications | 2023 Feb 13 | 798 | 36781872 |
| Cryo-EM structure of adeno-associated virus 4 at 2.2 Å resolution. | Zane, Grant; Silveria, Mark; Meyer, Nancy; White, Tommi; Duan, Rui; Zou, Xiaoqin; Chapman, Michael | Acta crystallographica. Section D, Structural biology | 2023 Feb 01 | 140-153 | 36762860 |
| Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. | Zhan, Hong; Unchwaniwala, Nuruddin; Rebolledo-Viveros, Andrea; Pennington, Janice; Horswill, Mark; Broadberry, Roma; Myers, Jonathan; den Boon, Johan A; Grant, Timothy; Ahlquist, Paul | Proceedings of the National Academy of Sciences of the United States of America | 2023 Jan 31 | e2217412120 | 36693094 |
| Nanovaccines Displaying the Influenza Virus Hemagglutinin in an Inverted Orientation Elicit an Enhanced Stalk-Directed Antibody Response. | Frey, Steven J; Carreño, Juan Manuel; Bielak, Dominika; Arsiwala, Ammar; Altomare, Clara G; Varner, Chad; Rosen-Cheriyan, Tania; Bajic, Goran; Krammer, Florian; Kane, Ravi S | Advanced healthcare materials | 2023 Jan 23 | e2202729 | 36689343 |
| Cryo-EM reveals the molecular basis oflaminin polymerization and LN-lamininopathies. | Kulczyk, Arkadiusz W; McKee, Karen K; Zhang, Ximo; Bizukojc, Iwona; Yu, Ying Q; Yurchenco, Peter D | Nature communications | 2023 Jan 19 | 317 | 36658135 |
| Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1. | Srivastava, Dhiraj; Yadav, Ravi P; Singh, Sneha; Boyd, Kimberly; Artemyev, Nikolai O | Structure (London, England : 1993) | 2023 Mar 02 | 309-317.e5 | 36657440 |
| A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability. | Podgorski, Jennifer M; Freeman, Krista; Gosselin, Sophia; Huet, Alexis; Conway, James F; Bird, Mary; Grecco, John; Patel, Shreya; Jacobs-Sera, Deborah; Hatfull, Graham; Gogarten, Johann Peter; Ravantti, Janne; White, Simon J | Structure (London, England : 1993) | 2023 Mar 02 | 282-294.e5 | 36649709 |
| Structural basis of ferroportin inhibition by minihepcidin PR73. | Wilbon, Azaan Saalim; Shen, Jiemin; Ruchala, Piotr; Zhou, Ming; Pan, Yaping | PLoS biology | 2023 Jan | e3001936 | 36649314 |
| Mechanism of Ca2+ transport by ferroportin. | Shen, Jiemin; Wilbon, Azaan Saalim; Zhou, Ming; Pan, Yaping | eLife | 2023 Jan 17 | 36648329 | |
| Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. | Doran, Matthew H; Rynkiewicz, Michael J; Rasicci, David; Bodt, Skylar M L; Barry, Meaghan E; Bullitt, Esther; Yengo, Christopher M; Moore, Jeffrey R; Lehman, William | The Journal of general physiology | 2023 Mar 06 | 36633586 | |
| Inhibition of the proton-activated chloride channel PAC by PIP2. | Mihaljević, Ljubica; Ruan, Zheng; Osei-Owusu, James; Lü, Wei; Qiu, Zhaozhu | eLife | 2023 Jan 12 | 36633397 | |
| Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5. | Paidimuddala, Bhaskar; Cao, Jianhao; Nash, Grady; Xie, Qing; Wu, Hao; Zhang, Liman | Nature structural & molecular biology | 2023 Feb | 159-166 | 36604500 |
| Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. | Alexander, J Andrew N; Worrall, Liam J; Hu, Jinhong; Vuckovic, Marija; Satishkumar, Nidhi; Poon, Raymond; Sobhanifar, Solmaz; Rosell, Federico I; Jenkins, Joshua; Chiang, Daniel; Mosimann, Wesley A; Chambers, Henry F; Paetzel, Mark; Chatterjee, Som S; Strynadka, Natalie C J | Nature | 2023 Jan | 375-382 | 36599987 |
| Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction. | Kulczyk, Arkadiusz W; Sorzano, Carlos Oscar S; Grela, Przemysław; Tchórzewski, Marek; Tumer, Nilgun E; Li, Xiao-Ping | The Journal of biological chemistry | 2023 Jan | 102795 | 36528064 |
| Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. | Cruz, Victor Emmanuel; Sekulski, Kamil; Peddada, Nagesh; Sailer, Carolin; Balasubramanian, Sahana; Weirich, Christine S; Stengel, Florian; Erzberger, Jan P | Nature structural & molecular biology | 2022 Dec | 36482249 | |
| Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. | Doran, Matthew H; Rynkiewicz, Michael J; Pavadai, Elumalai; Bodt, Skylar M L; Rasicci, David; Moore, Jeffrey R; Yengo, Christopher M; Bullitt, Esther; Lehman, William | The Journal of general physiology | 2023 Feb 06 | 36459134 | |
| Structures of the holo CRISPR RNA-guided transposon integration complex. | Park, Jung-Un; Tsai, Amy Wei-Lun; Rizo, Alexandrea N; Truong, Vinh H; Wellner, Tristan X; Schargel, Richard D; Kellogg, Elizabeth H | Nature | 2023 Jan | 775-782 | 36442503 |
| PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. | Dhingra, Yukti; Suresh, Shravanti K; Juneja, Puneet; Sashital, Dipali G | Molecular cell | 2022 Nov 17 | 36272411 | |
| Structural principles of B cell antigen receptor assembly. | Dong, Ying; Pi, Xiong; Bartels-Burgahn, Frauke; Saltukoglu, Deniz; Liang, Zhuoyi; Yang, Jianying; Alt, Frederick W; Reth, Michael; Wu, Hao | Nature | 2022 Dec | 36228656 | |
| Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP2. | Yin, Ying; Zhang, Feng; Feng, Shasha; Butay, Kevin John; Borgnia, Mario J; Im, Wonpil; Lee, Seok-Yong | Science (New York, N.Y.) | 2022 10 14 | 36227998 | |
| Transient Prenyltransferase-Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase. | Faylo, Jacque L; van Eeuwen, Trevor; Gupta, Kushol; Murakami, Kenji; Christianson, David W | Biochemistry | 2022 Nov 01 | 36227241 | |
| Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage. | Finkelstein, Maxwell T; Parker Miller, Emma; Erdman, Molly C; Fera, Daniela | Frontiers in immunology | 2022 | 36225920 | |
| Cryo-EM structure-based selection of computed ligand poses enables design of MTA-synergic PRMT5 inhibitors of better potency. | Zhou, Wei; Yadav, Gaya P; Yang, Xiaozhi; Qin, Feng; Li, Chenglong; Jiang, Qiu-Xing | Communications biology | 2022 10 03 | 36192627 | |
| Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria. | Puskar, Ryan; Du Truong, Chloe; Swain, Kyle; Chowdhury, Saborni; Chan, Ka-Yi; Li, Shan; Cheng, Kai-Wen; Wang, Ting Yu; Poh, Yu-Ping; Mazor, Yuval; Liu, Haijun; Chou, Tsui-Fen; Nannenga, Brent L; Chiu, Po-Lin | Nature communications | 2022 Oct 03 | 36192412 | |
| Metallic support films reduce optical heating in cryogenic correlative light and electron tomography. | Dahlberg, Peter D; Perez, Davis; Hecksel, Corey W; Chiu, Wah; Moerner, W E | Journal of structural biology | 2022 Oct 01 | 36191745 | |
| Improved mammalian retromer cryo-EM structures reveal a new assembly interface. | Kendall, Amy K; Chandra, Mintu; Xie, Boyang; Wan, William; Jackson, Lauren P | The Journal of biological chemistry | 2022 Sep 26 | 36174678 | |
| Structural basis for APE1 processing DNA damage in the nucleosome. | Weaver, Tyler M; Hoitsma, Nicole M; Spencer, Jonah J; Gakhar, Lokesh; Schnicker, Nicholas J; Freudenthal, Bret D | Nature communications | 2022 09 14 | 36104361 | |
| Methotrexate recognition by the human reduced folate carrier SLC19A1. | Wright, Nicholas J; Fedor, Justin G; Zhang, Han; Jeong, Pyeonghwa; Suo, Yang; Yoo, Jiho; Hong, Jiyong; Im, Wonpil; Lee, Seok-Yong | Nature | 2022 09 | 36071163 | |
| Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. | Li, Shanshan; Palo, Michael Z; Pintilie, Grigore; Zhang, Xiaojing; Su, Zhaoming; Kappel, Kalli; Chiu, Wah; Zhang, Kaiming; Das, Rhiju | Proceedings of the National Academy of Sciences of the United States of America | 2022 Sep 13 | 36067294 | |
| The promise of cryo-EM to explore RNA structural dynamics. | Bonilla, Steve L; Kieft, Jeffrey S | Journal of molecular biology | 2022 Sep 30 | 167802 | 36049551 |
| Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. | Zhu, Jiaqiang; Huang, Wei; Zhao, Jing; Huynh, Loc; Taylor, Derek J; Harris, Michael E | Nature communications | 2022 08 31 | 36045135 | |
| Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA. | Bonilla, Steve L; Vicens, Quentin; Kieft, Jeffrey S | Science advances | 2022 Aug 26 | 36026457 | |
| Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery. | Mangala Prasad, Vidya; Blijleven, Jelle S; Smit, Jolanda M; Lee, Kelly K | Nature communications | 2022 08 15 | 35970990 | |
| Autoantibody mimicry of hormone action at the thyrotropin receptor. | Faust, Bryan; Billesbølle, Christian B; Suomivuori, Carl-Mikael; Singh, Isha; Zhang, Kaihua; Hoppe, Nicholas; Pinto, Antonio F M; Diedrich, Jolene K; Muftuoglu, Yagmur; Szkudlinski, Mariusz W; Saghatelian, Alan; Dror, Ron O; Cheng, Yifan; Manglik, Aashish | Nature | 2022 09 | 35940205 | |
| Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities. | Zhu, Shaotong; Sridhar, Akshay; Teng, Jinfeng; Howard, Rebecca J; Lindahl, Erik; Hibbs, Ryan E | Nature communications | 2022 08 06 | 35933426 | |
| Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt. | Yu, Zanlin; Chen, Junliang; Takagi, Enzo; Wang, Feng; Saha, Bidisha; Liu, Xi; Joubert, Lydia-Marie; Gleason, Catherine E; Jin, Mingliang; Li, Chengmin; Nowotny, Carlos; Agard, David; Cheng, Yifan; Pearce, David | The Journal of biological chemistry | 2022 Sep | 35926713 | |
| Structures of the nitrogenase complex prepared under catalytic turnover conditions. | Rutledge, Hannah L; Cook, Brian D; Nguyen, Hoang P M; Herzik Jr, Mark A; Tezcan, F Akif | Science (New York, N.Y.) | 2022 08 19 | 35901182 | |
| Conformational landscape of the yeast SAGA complex as revealed by cryo-EM. | Vasyliuk, Diana; Felt, Joeseph; Zhong, Ellen D; Berger, Bonnie; Davis, Joseph H; Yip, Calvin K | Scientific reports | 2022 07 19 | 35853968 | |
| Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3. | Fry, Michelle Y; Najdrová, Vladimíra; Maggiolo, Ailiena O; Saladi, Shyam M; Doležal, Pavel; Clemons Jr, William M | Nature structural & molecular biology | 2022 08 | 35851188 | |
| Three-dimensional structure-guided evolution of a ribosome with tethered subunits. | Kim, Do Soon; Watkins, Andrew; Bidstrup, Erik; Lee, Joongoo; Topkar, Ved; Kofman, Camila; Schwarz, Kevin J; Liu, Yan; Pintilie, Grigore; Roney, Emily; Das, Rhiju; Jewett, Michael C | Nature chemical biology | 2022 Jul 14 | 35836020 | |
| Architecture of the human erythrocyte ankyrin-1 complex. | Vallese, Francesca; Kim, Kookjoo; Yen, Laura Y; Johnston, Jake D; Noble, Alex J; Calì, Tito; Clarke, Oliver Biggs | Nature structural & molecular biology | 2022 07 | 35835865 | |
| Structural basis for inhibition and regulation of a chitin synthase from Candida albicans. | Ren, Zhenning; Chhetri, Abhishek; Guan, Ziqiang; Suo, Yang; Yokoyama, Kenichi; Lee, Seok-Yong | Nature structural & molecular biology | 2022 Jul | 35788183 | |
| Development of CryoVR, a virtual reality training system for hands-on cryoEM operations. | Dong, Jiahui; Li, Daoyi; Ozcan, Kadir; Wan, Dayu; Jiang, Wen; Chen, Yingjie | Acta crystallographica. Section D, Structural biology | 2022 Jul 01 | 35775989 | |
| Structure of the human cation-chloride cotransport KCC1 in an outward-open state. | Zhao, Yongxiang; Shen, Jiemin; Wang, Qinzhe; Ruiz Munevar, Manuel Jose; Vidossich, Pietro; De Vivo, Marco; Zhou, Ming; Cao, Erhu | Proceedings of the National Academy of Sciences of the United States of America | 2022 Jul 05 | 35759661 | |
| Superimmunity by pan-sarbecovirus nanobodies. | Xiang, Yufei; Huang, Wei; Liu, Hejun; Sang, Zhe; Nambulli, Sham; Tubiana, Jérôme; Williams Jr, Kevin L; Duprex, W Paul; Schneidman-Duhovny, Dina; Wilson, Ian A; Taylor, Derek J; Shi, Yi | Cell reports | 2022 Jun 28 | 35738279 | |
| Structures of an active type III-A CRISPR effector complex. | Smith, Eric M; Ferrell, Sé; Tokars, Valerie L; Mondragón, Alfonso | Structure (London, England : 1993) | 2022 Aug 04 | 35714601 | |
| Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody. | Callaway, Heather M; Zyla, Dawid; Larrous, Florence; de Melo, Guilherme Dias; Hastie, Kathryn M; Avalos, Ruben Diaz; Agarwal, Alyssa; Corti, Davide; Bourhy, Hervé; Saphire, Erica Ollmann | Science advances | 2022 Jun 17 | 35714192 | |
| Architecture of the linker-scaffold in the nuclear pore. | Petrovic, Stefan; Samanta, Dipanjan; Perriches, Thibaud; Bley, Christopher J; Thierbach, Karsten; Brown, Bonnie; Nie, Si; Mobbs, George W; Stevens, Taylor A; Liu, Xiaoyu; Tomaleri, Giovani Pinton; Schaus, Lucas; Hoelz, André | Science (New York, N.Y.) | 2022 06 10 | 35679425 | |
| Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold. | Fontana, Pietro; Dong, Ying; Pi, Xiong; Tong, Alexander B; Hecksel, Corey W; Wang, Longfei; Fu, Tian-Min; Bustamante, Carlos; Wu, Hao | Science (New York, N.Y.) | 2022 06 10 | 35679401 | |
| BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. | Xia, Min; David, Liron; Teater, Matt; Gutierrez, Johana; Wang, Xiang; Meydan, Cem; Lytle, Andrew; Slack, Graham W; Scott, David W; Morin, Ryan D; Onder, Ozlem; Elenitoba-Johnson, Kojo S J; Zamponi, Nahuel; Cerchietti, Leandro; Lu, Tianbao; Philippar, Ulrike; Fontan, Lorena; Wu, Hao; Melnick, Ari M | Cancer discovery | 2022 08 05 | 35658124 | |
| Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes. | Yu, You; Li, Shibai; Ser, Zheng; Kuang, Huihui; Than, Thane; Guan, Danying; Zhao, Xiaolan; Patel, Dinshaw J | Proceedings of the National Academy of Sciences of the United States of America | 2022 06 07 | 35648833 | |
| Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis. | Kwon, Do Hoon; Zhang, Feng; Fedor, Justin G; Suo, Yang; Lee, Seok-Yong | Nature communications | 2022 05 24 | 35610228 | |
| Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide. | Zhao, Yongxiang; Roy, Kasturi; Vidossich, Pietro; Cancedda, Laura; De Vivo, Marco; Forbush, Biff; Cao, Erhu | Nature communications | 2022 05 18 | 35585053 | |
| Active conformation of the p97-p47 unfoldase complex. | Xu, Yang; Han, Han; Cooney, Ian; Guo, Yuxuan; Moran, Noah G; Zuniga, Nathan R; Price, John C; Hill, Christopher P; Shen, Peter S | Nature communications | 2022 05 12 | 35552390 | |
| Allosteric interactions prime androgen receptor dimerization and activation. | Wasmuth, Elizabeth V; Broeck, Arnaud Vanden; LaClair, Justin R; Hoover, Elizabeth A; Lawrence, Kayla E; Paknejad, Navid; Pappas, Kyrie; Matthies, Doreen; Wang, Biran; Feng, Weiran; Watson, Philip A; Zinder, John C; Karthaus, Wouter R; de la Cruz, M Jason; Hite, Richard K; Manova-Todorova, Katia; Yu, Zhiheng; Weintraub, Susan T; Klinge, Sebastian; Sawyers, Charles L | Molecular cell | 2022 06 02 | 35447082 | |
| Structural diversity of the SARS-CoV-2 Omicron spike. | Gobeil, Sophie M-C; Henderson, Rory; Stalls, Victoria; Janowska, Katarzyna; Huang, Xiao; May, Aaron; Speakman, Micah; Beaudoin, Esther; Manne, Kartik; Li, Dapeng; Parks, Rob; Barr, Maggie; Deyton, Margaret; Martin, Mitchell; Mansouri, Katayoun; Edwards, Robert J; Eaton, Amanda; Montefiori, David C; Sempowski, Gregory D; Saunders, Kevin O; Wiehe, Kevin; Williams, Wilton; Korber, Bette; Haynes, Barton F; Acharya, Priyamvada | Molecular cell | 2022 06 02 | 35447081 | |
| Computational design of mechanically coupled axle-rotor protein assemblies. | Courbet, A; Hansen, J; Hsia, Y; Bethel, N; Park, Y-J; Xu, C; Moyer, A; Boyken, S E; Ueda, G; Nattermann, U; Nagarajan, D; Silva, D-A; Sheffler, W; Quispe, J; Nord, A; King, N; Bradley, P; Veesler, D; Kollman, J; Baker, D | Science (New York, N.Y.) | 2022 04 22 | 35446645 | |
| Opening of glutamate receptor channel to subconductance levels. | Yelshanskaya, Maria V; Patel, Dhilon S; Kottke, Christopher M; Kurnikova, Maria G; Sobolevsky, Alexander I | Nature | 2022 05 | 35444281 | |
| Cryo-EM structure of the prothrombin-prothrombinase complex. | Ruben, Eliza A; Summers, Brock; Rau, Michael J; Fitzpatrick, James A J; Di Cera, Enrico | Blood | 2022 06 16 | 35427420 | |
| Waffle Method: A general and flexible approach for improving throughput in FIB-milling. | Kelley, Kotaro; Raczkowski, Ashleigh M; Klykov, Oleg; Jaroenlak, Pattana; Bobe, Daija; Kopylov, Mykhailo; Eng, Edward T; Bhabha, Gira; Potter, Clinton S; Carragher, Bridget; Noble, Alex J | Nature communications | 2022 04 06 | 35387991 | |
| Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. | Liang, Wenguang G; Wijaya, Juwina; Wei, Hui; Noble, Alex J; Mancl, Jordan M; Mo, Swansea; Lee, David; Lin King, John V; Pan, Man; Liu, Chang; Koehler, Carla M; Zhao, Minglei; Potter, Clinton S; Carragher, Bridget; Li, Sheng; Tang, Wei-Jen | Nature communications | 2022 04 05 | 35383169 | |
| Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation. | Abskharon, Romany; Sawaya, Michael R; Boyer, David R; Cao, Qin; Nguyen, Binh A; Cascio, Duilio; Eisenberg, David S | Proceedings of the National Academy of Sciences of the United States of America | 2022 04 12 | 35377792 | |
| 50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA. | Laughlin, Zane T; Nandi, Suparno; Dey, Debayan; Zelinskaya, Natalia; Witek, Marta A; Srinivas, Pooja; Nguyen, Ha An; Kuiper, Emily G; Comstock, Lindsay R; Dunham, Christine M; Conn, Graeme L | Proceedings of the National Academy of Sciences of the United States of America | 2022 Apr 05 | 35357969 | |
| Structural mechanism of muscle nicotinic receptor desensitization and block by curare. | Rahman, Md Mahfuzur; Basta, Tamara; Teng, Jinfeng; Lee, Myeongseon; Worrell, Brady T; Stowell, Michael H B; Hibbs, Ryan E | Nature structural & molecular biology | 2022 04 | 35301478 | |
| Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer. | Koo, Christopher W; Tucci, Frank J; He, Yuan; Rosenzweig, Amy C | Science (New York, N.Y.) | 2022 03 18 | 35298269 | |
| Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. | Kafai, Natasha M; Williamson, Lauren E; Binshtein, Elad; Sukupolvi-Petty, Soila; Gardner, Christina L; Liu, Jaclyn; Mackin, Samantha; Kim, Arthur S; Kose, Nurgun; Carnahan, Robert H; Jung, Ana; Droit, Lindsay; Reed, Douglas S; Handley, Scott A; Klimstra, William B; Crowe, James E; Diamond, Michael S | The Journal of experimental medicine | 2022 04 04 | 35297953 | |
| The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation. | Khandelwal, Nitesh Kumar; Millan, Cinthia R; Zangari, Samantha I; Avila, Samantha; Williams, Dewight; Thaker, Tarjani M; Tomasiak, Thomas M | Nature communications | 2022 Mar 11 | 35277487 | |
| Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. | Chen, James; Wang, Qi; Malone, Brandon; Llewellyn, Eliza; Pechersky, Yakov; Maruthi, Kashyap; Eng, Ed T; Perry, Jason K; Campbell, Elizabeth A; Shaw, David E; Darst, Seth A | Nature structural & molecular biology | 2022 03 | 35260847 | |
| Development of an atmospheric plasma jet device for versatile treatment of electron microscope sample grids. | Ahn, Eungjin; Tang, Tianyu; Kim, Byungchul; Lee, Hae June; Cho, Uhn-Soo | The Journal of biological chemistry | 2022 Apr | 35248533 | |
| Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. | Tsai, Kaitlyn; Stojković, Vanja; Lee, D John; Young, Iris D; Szal, Teresa; Klepacki, Dorota; Vázquez-Laslop, Nora; Mankin, Alexander S; Fraser, James S; Fujimori, Danica Galonić | Nature structural & molecular biology | 2022 02 | 35165456 | |
| Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P2 and rapamycin. | Gan, Ninghai; Han, Yan; Zeng, Weizhong; Wang, Yan; Xue, Jing; Jiang, Youxing | Proceedings of the National Academy of Sciences of the United States of America | 2022 Feb 15 | 35131932 | |
| Gating choreography and mechanism of the human proton-activated chloride channel ASOR. | Science advances | 2022 Feb 04 | 35108041 | ||
| A Robust Single-Particle Cryo-Electron Microscopy (cryo-EM) Processing Workflow with cryoSPARC, RELION, and Scipion. | DiIorio, Megan C; Kulczyk, Arkadiusz W | Journal of visualized experiments : JoVE | 2022 01 31 | 35104261 | |
| An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. | Morgan, Christopher E; Zhang, Zhemin; Bonomo, Robert A; Yu, Edward W | mBio | 2022 Feb 01 | 35100868 | |
| Label-free visual proteomics: Coupling MS- and EM-based approaches in structural biology. | Klykov, Oleg; Kopylov, Mykhailo; Carragher, Bridget; Heck, Albert J R; Noble, Alex J; Scheltema, Richard A | Molecular cell | 2022 01 20 | 35063097 | |
| Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. | Yang, Chun; Fujiwara, Rina; Kim, Hee Jong; Basnet, Pratik; Zhu, Yunye; Gorbea Colón, Jose J; Steimle, Stefan; Garcia, Benjamin A; Kaplan, Craig D; Murakami, Kenji | Molecular cell | 2022 02 03 | 35051353 | |
| Structure of the human cone photoreceptor cyclic nucleotide-gated channel. | Zheng, Xiangdong; Hu, Zhengshan; Li, Huan; Yang, Jian | Nature structural & molecular biology | 2022 Jan | 34969976 | |
| Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography. | Elferich, Johannes; Clark, Sarah; Ge, Jingpeng; Goehring, April; Matsui, Aya; Gouaux, Eric | eLife | 2021 12 29 | 34964715 | |
| Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter. | Thaker, Tarjani M; Mishra, Smriti; Zhou, Wenchang; Mohan, Michael; Tang, Qingyu; Faraldo-Goméz, José D; Mchaourab, Hassane S; Tomasiak, Thomas M | Nature chemical biology | 2022 02 | 34931066 | |
| Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer. | Hu, Wenxin; Zheng, Hongjin | Communications biology | 2021 12 09 | 34887516 | |
| NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. | Andreeva, Liudmila; David, Liron; Rawson, Shaun; Shen, Chen; Pasricha, Teerithveen; Pelegrin, Pablo; Wu, Hao | Cell | 2021 12 22 | 34861190 | |
| Illumination of serotonin transporter mechanism and role of the allosteric site. | Yang, Dongxue; Gouaux, Eric | Science advances | 2021 Dec 03 | 34851672 | |
| De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. | Chen, Kai-En; Guo, Qian; Hill, Timothy A; Cui, Yi; Kendall, Amy K; Yang, Zhe; Hall, Ryan J; Healy, Michael D; Sacharz, Joanna; Norwood, Suzanne J; Fonseka, Sachini; Xie, Boyang; Reid, Robert C; Leneva, Natalya; Parton, Robert G; Ghai, Rajesh; Stroud, David A; Fairlie, David P; Suga, Hiroaki; Jackson, Lauren P; Teasdale, Rohan D; Passioura, Toby; Collins, Brett M | Science advances | 2021 Dec 03 | 34851660 | |
| Broadening access to cryoEM through centralized facilities. | Zimanyi, Christina M; Kopylov, Mykhailo; Potter, Clinton S; Carragher, Bridget; Eng, Edward T | Trends in biochemical sciences | 2022 Feb | 34823974 | |
| A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure. | Bonilla, Steve L; Sherlock, Madeline E; MacFadden, Andrea; Kieft, Jeffrey S | Science (New York, N.Y.) | 2021 11 19 | 34793227 | |
| Mapping the catalytic conformations of an assembly-line polyketide synthase module. | Cogan, Dillon P; Zhang, Kaiming; Li, Xiuyuan; Li, Shanshan; Pintilie, Grigore D; Roh, Soung-Hun; Craik, Charles S; Chiu, Wah; Khosla, Chaitan | Science (New York, N.Y.) | 2021 11 05 | 34735239 | |
| Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole. | Neuberger, Arthur; Nadezhdin, Kirill D; Sobolevsky, Alexander I | Nature communications | 2021 11 01 | 34725357 | |
| Selective G protein signaling driven by substance P-neurokinin receptor dynamics. | Harris, Julian A; Faust, Bryan; Gondin, Arisbel B; Dämgen, Marc André; Suomivuori, Carl-Mikael; Veldhuis, Nicholas A; Cheng, Yifan; Dror, Ron O; Thal, David M; Manglik, Aashish | Nature chemical biology | 2021 Oct 28 | 34711980 | |
| Vascular KATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. | Sung, Min Woo; Yang, Zhongying; Driggers, Camden M; Patton, Bruce L; Mostofian, Barmak; Russo, John D; Zuckerman, Daniel M; Shyng, Show-Ling | Proceedings of the National Academy of Sciences of the United States of America | 2021 11 02 | 34711681 | |
| Electron crystallography of chiral and non-chiral small molecules. | Zhou, Weijiang; Bammes, Benjamin; Mitchell, Patrick G; Betz, Kerry; Chiu, Wah | Ultramicroscopy | 2021 Oct 19 | 34695647 | |
| Structure and desensitization of AMPA receptor complexes with type II TARP γ5 and GSG1L. | Klykov, Oleg; Gangwar, Shanti Pal; Yelshanskaya, Maria V; Yen, Laura; Sobolevsky, Alexander I | Molecular cell | 2021 12 02 | 34678168 | |
| Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses. | Feldman, Jared; Bals, Julia; Altomare, Clara G; St Denis, Kerri; Lam, Evan C; Hauser, Blake M; Ronsard, Larance; Sangesland, Maya; Moreno, Thalia Bracamonte; Okonkwo, Vintus; Hartojo, Nathania; Balazs, Alejandro B; Bajic, Goran; Lingwood, Daniel; Schmidt, Aaron G | Science immunology | 2021 12 10 | 34648356 | |
| Structural basis of chromatin regulation by histone variant H2A.Z. | Lewis, Tyler S; Sokolova, Vladyslava; Jung, Harry; Ng, Honkit; Tan, Dongyan | Nucleic acids research | 2021 Nov 08 | 34643712 | |
| Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. | Scortecci, Jessica Fernandes; Molday, Laurie L; Curtis, Susan B; Garces, Fabian A; Panwar, Pankaj; Van Petegem, Filip; Molday, Robert S | Nature communications | 2021 10 08 | 34625547 | |
| Micropatterning Transmission Electron Microscopy Grids to Direct Cell Positioning within Whole-Cell Cryo-Electron Tomography Workflows. | Sibert, Bryan S; Kim, Joseph Y; Yang, Jie E; Wright, Elizabeth R | Journal of visualized experiments : JoVE | 2021 09 13 | 34570100 | |
| Architecture and assembly mechanism of native glycine receptors. | Zhu, Hongtao; Gouaux, Eric | Nature | 2021 11 | 34555840 | |
| AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. | Caffrey, Brian; Zhu, Xing; Berezuk, Alison; Tuttle, Katharine; Chittori, Sagar; Subramaniam, Sriram | The Journal of biological chemistry | 2021 10 | 34520757 | |
| Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. | Novikova, Irina V; Zhou, Mowei; Du, Chen; Parra, Marcelina; Kim, Doo Nam; VanAernum, Zachary L; Shaw, Jared B; Hellmann, Hanjo; Wysocki, Vicki H; Evans, James E | ACS chemical biology | 2021 11 19 | 34520180 | |
| Computational Methods for Single-Particle Electron Cryomicroscopy. | Singer, Amit; Sigworth, Fred J | Annual review of biomedical data science | 2020 07 | 34485850 | |
| A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants. | Schmitz, Aaron J; Turner, Jackson S; Liu, Zhuoming; Zhou, Julian Q; Aziati, Ishmael D; Chen, Rita E; Joshi, Astha; Bricker, Traci L; Darling, Tamarand L; Adelsberg, Daniel C; Altomare, Clara G; Alsoussi, Wafaa B; Case, James Brett; VanBlargan, Laura A; Lei, Tingting; Thapa, Mahima; Amanat, Fatima; Jeevan, Trushar; Fabrizio, Thomas; O'Halloran, Jane A; Shi, Pei-Yong; Presti, Rachel M; Webby, Richard J; Krammer, Florian; Whelan, Sean P J; Bajic, Goran; Diamond, Michael S; Boon, Adrianus C M; Ellebedy, Ali H | Immunity | 2021 09 14 | 34464596 | |
| Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation. | Rathinaswamy, Manoj K; Dalwadi, Udit; Fleming, Kaelin D; Adams, Carson; Stariha, Jordan T B; Pardon, Els; Baek, Minkyung; Vadas, Oscar; DiMaio, Frank; Steyaert, Jan; Hansen, Scott D; Yip, Calvin K; Burke, John E | Science advances | 2021 Aug | 34452907 | |
| Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. | Zhang, Kaiming; Zheludev, Ivan N; Hagey, Rachel J; Haslecker, Raphael; Hou, Yixuan J; Kretsch, Rachael; Pintilie, Grigore D; Rangan, Ramya; Kladwang, Wipapat; Li, Shanshan; Wu, Marie Teng-Pei; Pham, Edward A; Bernardin-Souibgui, Claire; Baric, Ralph S; Sheahan, Timothy P; D'Souza, Victoria; Glenn, Jeffrey S; Chiu, Wah; Das, Rhiju | Nature structural & molecular biology | 2021 09 | 34426697 | |
| The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. | Plenge, Per; Yang, Dongxue; Salomon, Kristine; Laursen, Louise; Kalenderoglou, Iris E; Newman, Amy H; Gouaux, Eric; Coleman, Jonathan A; Loland, Claus J | Nature communications | 2021 08 20 | 34417466 | |
| Structural and mechanistic basis for protein glutamylation by the kinase fold. | Osinski, Adam; Black, Miles H; Pawłowski, Krzysztof; Chen, Zhe; Li, Yang; Tagliabracci, Vincent S | Molecular cell | 2021 Aug 12 | 34407442 | |
| Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. | Su, Chih-Chia; Klenotic, Philip A; Cui, Meng; Lyu, Meinan; Morgan, Christopher E; Yu, Edward W | PLoS biology | 2021 Aug | 34383749 | |
| Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution. | Su, Zhaoming; Zhang, Kaiming; Kappel, Kalli; Li, Shanshan; Palo, Michael Z; Pintilie, Grigore D; Rangan, Ramya; Luo, Bingnan; Wei, Yuquan; Das, Rhiju; Chiu, Wah | Nature | 2021 Aug | 34381213 | |
| HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases. | Rathinaswamy, Manoj K; Fleming, Kaelin D; Dalwadi, Udit; Pardon, Els; Harris, Noah J; Yip, Calvin K; Steyaert, Jan; Burke, John E | Structure (London, England : 1993) | 2021 12 02 | 34348129 | |
| Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes. | Sun, Dapeng; Sang, Zhe; Kim, Yong Joon; Xiang, Yufei; Cohen, Tomer; Belford, Anna K; Huet, Alexis; Conway, James F; Sun, Ji; Taylor, Derek J; Schneidman-Duhovny, Dina; Zhang, Cheng; Huang, Wei; Shi, Yi | Nature communications | 2021 08 03 | 34344900 | |
| Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. | Hu, Qi; Botuyan, Maria Victoria; Zhao, Debiao; Cui, Gaofeng; Mer, Elie; Mer, Georges | Nature | 2021 08 | 34321665 | |
| Allosteric Inhibition of a Vesicular Glutamate Transporter by an Isoform-Specific Antibody. | Eriksen, Jacob; Li, Fei; Stroud, Robert M; Edwards, Robert H | Biochemistry | 2021 08 17 | 34319067 | |
| Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60. | Wang, Joseph Che-Yen; Chen, Lingling | Scientific reports | 2021 07 20 | 34285302 | |
| Structural basis for potassium transport in prokaryotes by KdpFABC. | Sweet, Marie E; Larsen, Casper; Zhang, Xihui; Schlame, Michael; Pedersen, Bjørn P; Stokes, David L | Proceedings of the National Academy of Sciences of the United States of America | 2021 Jul 20 | 34272288 | |
| Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. | Lopez-Redondo, Maria; Fan, Shujie; Koide, Akiko; Koide, Shohei; Beckstein, Oliver; Stokes, David L | The Journal of general physiology | 2021 Aug 02 | 34254979 | |
| In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. | Li, Dapeng; Edwards, Robert J; Manne, Kartik; Martinez, David R; Schäfer, Alexandra; Alam, S Munir; Wiehe, Kevin; Lu, Xiaozhi; Parks, Robert; Sutherland, Laura L; Oguin 3rd, Thomas H; McDanal, Charlene; Perez, Lautaro G; Mansouri, Katayoun; Gobeil, Sophie M C; Janowska, Katarzyna; Stalls, Victoria; Kopp, Megan; Cai, Fangping; Lee, Esther; Foulger, Andrew; Hernandez, Giovanna E; Sanzone, Aja; Tilahun, Kedamawit; Jiang, Chuancang; Tse, Longping V; Bock, Kevin W; Minai, Mahnaz; Nagata, Bianca M; Cronin, Kenneth; Gee-Lai, Victoria; Deyton, Margaret; Barr, Maggie; Von Holle, Tarra; Macintyre, Andrew N; Stover, Erica; Feldman, Jared; Hauser, Blake M; Caradonna, Timothy M; Scobey, Trevor D; Rountree, Wes; Wang, Yunfei; Moody, M Anthony; Cain, Derek W; DeMarco, C Todd; Denny, Thomas N; Woods, Christopher W; Petzold, Elizabeth W; Schmidt, Aaron G; Teng, I-Ting; Zhou, Tongqing; Kwong, Peter D; Mascola, John R; Graham, Barney S; Moore, Ian N; Seder, Robert; Andersen, Hanne; Lewis, Mark G; Montefiori, David C; Sempowski, Gregory D; Baric, Ralph S; Acharya, Priyamvada; Haynes, Barton F; Saunders, Kevin O | Cell | 2021 08 05 | 34242577 | |
| Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. | Nadezhdin, Kirill D; Neuberger, Arthur; Trofimov, Yuri A; Krylov, Nikolay A; Sinica, Viktor; Kupko, Nikita; Vlachova, Viktorie; Zakharian, Eleonora; Efremov, Roman G; Sobolevsky, Alexander I | Nature structural & molecular biology | 2021 07 | 34239124 | |
| Heat-dependent opening of TRPV1 in the presence of capsaicin. | Kwon, Do Hoon; Zhang, Feng; Suo, Yang; Bouvette, Jonathan; Borgnia, Mario J; Lee, Seok-Yong | Nature structural & molecular biology | 2021 07 | 34239123 | |
| Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. | Gobeil, Sophie M-C; Janowska, Katarzyna; McDowell, Shana; Mansouri, Katayoun; Parks, Robert; Stalls, Victoria; Kopp, Megan F; Manne, Kartik; Li, Dapeng; Wiehe, Kevin; Saunders, Kevin O; Edwards, Robert J; Korber, Bette; Haynes, Barton F; Henderson, Rory; Acharya, Priyamvada | Science (New York, N.Y.) | 2021 08 06 | 34168071 | |
| Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection. | Chen, Peng; Zeng, Ji; Liu, Zheng; Thaker, Hatim; Wang, Siyu; Tian, Songhai; Zhang, Jie; Tao, Liang; Gutierrez, Craig B; Xing, Li; Gerhard, Ralf; Huang, Lan; Dong, Min; Jin, Rongsheng | Nature communications | 2021 06 18 | 34145250 | |
| Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies. | Cerutti, Gabriele; Rapp, Micah; Guo, Yicheng; Bahna, Fabiana; Bimela, Jude; Reddem, Eswar R; Yu, Jian; Wang, Pengfei; Liu, Lihong; Huang, Yaoxing; Ho, David D; Kwong, Peter D; Sheng, Zizhang; Shapiro, Lawrence | Structure (London, England : 1993) | 2021 07 01 | 34111408 | |
| Structural insight on assembly-line catalysis in terpene biosynthesis. | Faylo, Jacque L; van Eeuwen, Trevor; Kim, Hee Jong; Gorbea Colón, Jose J; Garcia, Benjamin A; Murakami, Kenji; Christianson, David W | Nature communications | 2021 06 09 | 34108468 | |
| Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair. | van Eeuwen, Trevor; Shim, Yoonjung; Kim, Hee Jong; Zhao, Tingting; Basu, Shrabani; Garcia, Benjamin A; Kaplan, Craig D; Min, Jung-Hyun; Murakami, Kenji | Nature communications | 2021 06 07 | 34099686 | |
| Production and purification of ATP-sensitive potassium channel particles for cryo-electron microscopy. | Driggers, Camden M; Shyng, Show-Ling | Methods in enzymology | 2021 | 34099169 | |
| Structure and function at the lipid-protein interface of a pentameric ligand-gated ion channel. | Kumar, Pramod; Cymes, Gisela D; Grosman, Claudio | Proceedings of the National Academy of Sciences of the United States of America | 2021 06 08 | 34083441 | |
| TRPV3 expression and purification for structure determination by Cryo-EM. | Neuberger, Arthur; Nadezhdin, Kirill D; Sobolevsky, Alexander I | Methods in enzymology | 2021 | 34059288 | |
| Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment. | Sharif, Humayun; Hollingsworth, L Robert; Griswold, Andrew R; Hsiao, Jeffrey C; Wang, Qinghui; Bachovchin, Daniel A; Wu, Hao | Immunity | 2021 07 13 | 34019797 | |
| Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. | Williams, Wilton B; Meyerhoff, R Ryan; Edwards, R J; Li, Hui; Manne, Kartik; Nicely, Nathan I; Henderson, Rory; Zhou, Ye; Janowska, Katarzyna; Mansouri, Katayoun; Gobeil, Sophie; Evangelous, Tyler; Hora, Bhavna; Berry, Madison; Abuahmad, A Yousef; Sprenz, Jordan; Deyton, Margaret; Stalls, Victoria; Kopp, Megan; Hsu, Allen L; Borgnia, Mario J; Stewart-Jones, Guillaume B E; Lee, Matthew S; Bronkema, Naomi; Moody, M Anthony; Wiehe, Kevin; Bradley, Todd; Alam, S Munir; Parks, Robert J; Foulger, Andrew; Oguin, Thomas; Sempowski, Gregory D; Bonsignori, Mattia; LaBranche, Celia C; Montefiori, David C; Seaman, Michael; Santra, Sampa; Perfect, John; Francica, Joseph R; Lynn, Geoffrey M; Aussedat, Baptiste; Walkowicz, William E; Laga, Richard; Kelsoe, Garnett; Saunders, Kevin O; Fera, Daniela; Kwong, Peter D; Seder, Robert A; Bartesaghi, Alberto; Shaw, George M; Acharya, Priyamvada; Haynes, Barton F | Cell | 2021 05 27 | 34019795 | |
| Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. | Yu, Jie; Rao, Prashant; Clark, Sarah; Mitra, Jaba; Ha, Taekjip; Gouaux, Eric | Nature | 2021 Jun | 33981040 | |
| Structures of telomerase at several steps of telomere repeat synthesis. | He, Yao; Wang, Yaqiang; Liu, Baocheng; Helmling, Christina; Sušac, Lukas; Cheng, Ryan; Zhou, Z Hong; Feigon, Juli | Nature | 2021 05 | 33981033 | |
| Cryo-EM structure of a thermostable bacterial nanocompartment. | Wiryaman, Timothy; Toor, Navtej | IUCrJ | 2021 May 01 | 33953921 | |
| Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. | Malone, Brandon; Chen, James; Wang, Qi; Llewellyn, Eliza; Choi, Young Joo; Olinares, Paul Dominic B; Cao, Xinyun; Hernandez, Carolina; Eng, Edward T; Chait, Brian T; Shaw, David E; Landick, Robert; Darst, Seth A; Campbell, Elizabeth A | Proceedings of the National Academy of Sciences of the United States of America | 2021 05 11 | 33883267 | |
| Structural basis of long-range to short-range synaptic transition in NHEJ. | Chen, Siyu; Lee, Linda; Naila, Tasmin; Fishbain, Susan; Wang, Annie; Tomkinson, Alan E; Lees-Miller, Susan P; He, Yuan | Nature | 2021 May | 33854234 | |
| Extracellular cap domain is an essential component of the TRPV1 gating mechanism. | Nadezhdin, Kirill D; Neuberger, Arthur; Nikolaev, Yury A; Murphy, Lyle A; Gracheva, Elena O; Bagriantsev, Sviatoslav N; Sobolevsky, Alexander I | Nature communications | 2021 04 12 | 33846324 | |
| Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM. | Shen, Betty W; Quispe, Joel D; Luyten, Yvette; McGough, Benjamin E; Morgan, Richard D; Stoddard, Barry L | Structure (London, England : 1993) | 2021 Jun 03 | 33826880 | |
| Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class. | Rapp, Micah; Guo, Yicheng; Reddem, Eswar R; Yu, Jian; Liu, Lihong; Wang, Pengfei; Cerutti, Gabriele; Katsamba, Phinikoula; Bimela, Jude S; Bahna, Fabiana A; Mannepalli, Seetha M; Zhang, Baoshan; Kwong, Peter D; Huang, Yaoxing; Ho, David D; Shapiro, Lawrence; Sheng, Zizhang | Cell reports | 2021 04 06 | 33794145 | |
| Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. | Cerutti, Gabriele; Guo, Yicheng; Zhou, Tongqing; Gorman, Jason; Lee, Myungjin; Rapp, Micah; Reddem, Eswar R; Yu, Jian; Bahna, Fabiana; Bimela, Jude; Huang, Yaoxing; Katsamba, Phinikoula S; Liu, Lihong; Nair, Manoj S; Rawi, Reda; Olia, Adam S; Wang, Pengfei; Zhang, Baoshan; Chuang, Gwo-Yu; Ho, David D; Sheng, Zizhang; Kwong, Peter D; Shapiro, Lawrence | Cell host & microbe | 2021 05 12 | 33789084 | |
| Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation. | Jette, Claudia A; Barnes, Christopher O; Kirk, Sharon M; Melillo, Bruno; Smith 3rd, Amos B; Bjorkman, Pamela J | Nature communications | 2021 03 29 | 33782388 | |
| Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. | Malone, Brandon; Chen, James; Wang, Qi; Llewellyn, Eliza; Choi, Young Joo; Olinares, Paul Dominic B; Cao, Xinyun; Hernandez, Carolina; Eng, Edward T; Chait, Brian T; Shaw, David E; Landick, Robert; Darst, Seth A; Campbell, Elizabeth A | bioRxiv : the preprint server for biology | 2021 Mar 14 | 33758867 | |
| Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes. | Sun, Dapeng; Sang, Zhe; Kim, Yong Joon; Xiang, Yufei; Cohen, Tomer; Belford, Anna K; Huet, Alexis; Conway, James F; Sun, Ji; Taylor, Derek J; Schneidman-Duhovny, Dina; Zhang, Cheng; Huang, Wei; Shi, Yi | bioRxiv : the preprint server for biology | 2021 Mar 10 | 33758850 | |
| Structure and gating mechanism of the α7 nicotinic acetylcholine receptor. | Noviello, Colleen M; Gharpure, Anant; Mukhtasimova, Nuriya; Cabuco, Rico; Baxter, Leah; Borek, Dominika; Sine, Steven M; Hibbs, Ryan E | Cell | 2021 Apr 15 | 33735609 | |
| DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation. | Hollingsworth, L Robert; Sharif, Humayun; Griswold, Andrew R; Fontana, Pietro; Mintseris, Julian; Dagbay, Kevin B; Paulo, Joao A; Gygi, Steven P; Bachovchin, Daniel A; Wu, Hao | Nature | 2021 Apr | 33731932 | |
| Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants. | Moghadamchargari, Zahra; Shirzadeh, Mehdi; Liu, Chang; Schrecke, Samantha; Packianathan, Charles; Russell, David H; Zhao, Minglei; Laganowsky, Arthur | Proceedings of the National Academy of Sciences of the United States of America | 2021 Mar 23 | 33723061 | |
| Structure of the human Mediator-bound transcription preinitiation complex. | Abdella, R; Talyzina, A; Chen, S; Inouye, C J; Tjian, R; He, Y | Science (New York, N.Y.) | 2021 04 02 | 33707221 | |
| CorRelator: Interactive software for real-time high precision cryo-correlative light and electron microscopy. | Yang, Jie E; Larson, Matthew R; Sibert, Bryan S; Shrum, Samantha; Wright, Elizabeth R | Journal of structural biology | 2021 Feb 18 | 33610654 | |
| Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses. | Feldman, Jared; Bals, Julia; Altomare, Clara G; St Denis, Kerri; Lam, Evan C; Hauser, Blake M; Ronsard, Larance; Sangesland, Maya; Moreno, Thalia Bracamonte; Okonkwo, Vintus; Hartojo, Nathania; Balazs, Alejandro B; Bajic, Goran; Lingwood, Daniel; Schmidt, Aaron G | bioRxiv : the preprint server for biology | 2021 Jul 09 | 33594359 | |
| Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery. | Herrera, Marco; Kim, Jeonghwan; Eygeris, Yulia; Jozic, Antony; Sahay, Gaurav | Biomaterials science | 2021 Jun 15 | 33586742 | |
| Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. | Grau, Daniel; Zhang, Yixiao; Lee, Chul-Hwan; Valencia-Sánchez, Marco; Zhang, Jenny; Wang, Miao; Holder, Marlene; Svetlov, Vladimir; Tan, Dongyan; Nudler, Evgeny; Reinberg, Danny; Walz, Thomas; Armache, Karim-Jean | Nature communications | 2021 01 29 | 33514705 | |
| Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis. | Herrera, Natalia G; Morano, Nicholas C; Celikgil, Alev; Georgiev, George I; Malonis, Ryan J; Lee, James H; Tong, Karen; Vergnolle, Olivia; Massimi, Aldo B; Yen, Laura Y; Noble, Alex J; Kopylov, Mykhailo; Bonanno, Jeffrey B; Garrett-Thomson, Sarah C; Hayes, David B; Bortz 3rd, Robert H; Wirchnianski, Ariel S; Florez, Catalina; Laudermilch, Ethan; Haslwanter, Denise; Fels, J Maximilian; Dieterle, M Eugenia; Jangra, Rohit K; Barnhill, Jason; Mengotto, Amanda; Kimmel, Duncan; Daily, Johanna P; Pirofski, Liise-Anne; Chandran, Kartik; Brenowitz, Michael; Garforth, Scott J; Eng, Edward T; Lai, Jonathan R; Almo, Steven C | ACS omega | 2021 Jan 12 | 33458462 | |
| The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain. | Rangarajan, Erumbi S; Izard, Tina | International journal of molecular sciences | 2021 Jan 11 | 33440717 | |
| Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. | Robert Hollingsworth, L; David, Liron; Li, Yang; Griswold, Andrew R; Ruan, Jianbin; Sharif, Humayun; Fontana, Pietro; Orth-He, Elizabeth L; Fu, Tian-Min; Bachovchin, Daniel A; Wu, Hao | Nature communications | 2021 01 08 | 33420033 | |
| D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. | Gobeil, Sophie M-C; Janowska, Katarzyna; McDowell, Shana; Mansouri, Katayoun; Parks, Robert; Manne, Kartik; Stalls, Victoria; Kopp, Megan F; Henderson, Rory; Edwards, Robert J; Haynes, Barton F; Acharya, Priyamvada | Cell reports | 2021 01 12 | 33417835 | |
| Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. | Kato, Kazuki; Ahmad, Sadeem; Zhu, Zixiang; Young, Janet M; Mu, Xin; Park, Sehoon; Malik, Harmit S; Hur, Sun | Molecular cell | 2021 02 04 | 33373584 | |
| Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. | Zhou, Tongqing; Tsybovsky, Yaroslav; Gorman, Jason; Rapp, Micah; Cerutti, Gabriele; Chuang, Gwo-Yu; Katsamba, Phinikoula S; Sampson, Jared M; Schön, Arne; Bimela, Jude; Boyington, Jeffrey C; Nazzari, Alexandra; Olia, Adam S; Shi, Wei; Sastry, Mallika; Stephens, Tyler; Stuckey, Jonathan; Teng, I-Ting; Wang, Pengfei; Wang, Shuishu; Zhang, Baoshan; Friesner, Richard A; Ho, David D; Mascola, John R; Shapiro, Lawrence; Kwong, Peter D | Cell host & microbe. | 2020 12 09; | 33271067 | |
| The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states. | Santosh, Vishaka; Musayev, Faik N; Jaiswal, Rahul; Zárate-Pérez, Francisco; Vandewinkel, Bram; Dierckx, Caroline; Endicott, Molly; Sharifi, Kamyar; Dryden, Kelly; Henckaerts, Els; Escalante, Carlos R | Nucleic acids research | 2020 12 16 | 33270897 | |
| The Structure of an AAV5-AAVR Complex at 2.5 Å Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors. | Silveria, Mark A; Large, Edward E; Zane, Grant M; White, Tommi A; Chapman, Michael S | Viruses | 2020 11 18 | 33218165 | |
| Native Mass Spectrometry-Based Screening for Optimal Sample Preparation in Single-Particle Cryo-EM. | Olinares, Paul Dominic B; Kang, Jin Young; Llewellyn, Eliza; Chiu, Courtney; Chen, James; Malone, Brandon; Saecker, Ruth M; Campbell, Elizabeth A; Darst, Seth A; Chait, Brian T | Structure (London, England : 1993) | 2021 02 04 | 33217329 | |
| Structural Basis for Virulence Activation of Francisella tularensis. | Travis, Brady A; Ramsey, Kathryn M; Prezioso, Samantha M; Tallo, Thomas; Wandzilak, Jamie M; Hsu, Allen; Borgnia, Mario; Bartesaghi, Alberto; Dove, Simon L; Brennan, Richard G; Schumacher, Maria A | Molecular cell | 2021 01 07 | 33217319 | |
| A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel. | Liu, Chang; Reese, Rebecca; Vu, Simon; Rougé, Lionel; Shields, Shannon D; Kakiuchi-Kiyota, Satoko; Chen, Huifen; Johnson, Kevin; Shi, Yu Patrick; Chernov-Rogan, Tania; Greiner, Demi Maria Zabala; Kohli, Pawan Bir; Hackos, David; Brillantes, Bobby; Tam, Christine; Li, Tianbo; Wang, Jianyong; Safina, Brian; Magnuson, Steve; Volgraf, Matthew; Payandeh, Jian; Zheng, Jie; Rohou, Alexis; Chen, Jun | Neuron | 2021 01 20 | 33152265 | |
| Adeno-Associated Virus (AAV-DJ)-Cryo-EM Structure at 1.56 Å Resolution. | Xie, Qing; Yoshioka, Craig K; Chapman, Michael S | Viruses | 2020 10 20 | 33092282 | |
| Synthetic group A streptogramin antibiotics that overcome Vat resistance. | Li, Qi; Pellegrino, Jenna; Lee, D John; Tran, Arthur A; Chaires, Hector A; Wang, Ruoxi; Park, Jesslyn E; Ji, Kaijie; Chow, David; Zhang, Na; Brilot, Axel F; Biel, Justin T; van Zundert, Gydo; Borrelli, Kenneth; Shinabarger, Dean; Wolfe, Cindy; Murray, Beverly; Jacobson, Matthew P; Mühle, Estelle; Chesneau, Olivier; Fraser, James S; Seiple, Ian B | Nature | 2020 10 | 32968273 | |
| Light-coupled cryo-plunger for time-resolved cryo-EM. | Yoder, Nate; Jalali-Yazdi, Farzad; Noreng, Sigrid; Houser, Alexandra; Baconguis, Isabelle; Gouaux, Eric | Journal of structural biology. | 2020 Sep 17; | 32950604 | |
| Shared structural mechanisms of general anaesthetics and benzodiazepines. | Kim, Jeong Joo; Gharpure, Anant; Teng, Jinfeng; Zhuang, Yuxuan; Howard, Rebecca J; Zhu, Shaotong; Noviello, Colleen M; Walsh Jr, Richard M; Lindahl, Erik; Hibbs, Ryan E | Nature | 2020 09 | 32879488 | |
| Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. | Durie, Clarissa L; Sheedlo, Michael J; Chung, Jeong Min; Byrne, Brenda G; Su, Min; Knight, Thomas; Swanson, Michele; Lacy, D Borden; Ohi, Melanie D | eLife. | 2020 Sep 02; | 32876045 | |
| Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. | Fromm, Simon A; Lawrence, Rosalie E; Hurley, James H | Nature structural & molecular biology. | 2020 Nov; | 32868926 | |
| Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9?Å. | Flores, Jonathan A; Haddad, Bassam G; Dolan, Kimberly A; Myers, Janette B; Yoshioka, Craig C; Copperman, Jeremy; Zuckerman, Daniel M; Reichow, Steve L | Nature communications. | 2020 08 28; | 32859914 | |
| Structural basis of transcription-translation coupling. | Wang, Chengyuan; Molodtsov, Vadim; Firlar, Emre; Kaelber, Jason T; Blaha, Gregor; Su, Min; Ebright, Richard H | Science (New York, N.Y.) | 2020 09 11 | 32820061 | |
| Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex. | Chen, James; Malone, Brandon; Llewellyn, Eliza; Grasso, Michael; Shelton, Patrick M M; Olinares, Paul Dominic B; Maruthi, Kashyap; Eng, Edward T; Vatandaslar, Hasan; Chait, Brian T; Kapoor, Tarun M; Darst, Seth A; Campbell, Elizabeth A | Cell. | 2020 09 17; | 32783916 | |
| Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. | Doran, Matthew H; Pavadai, Elumalai; Rynkiewicz, Michael J; Walklate, Jonathan; Bullitt, Esther; Moore, Jeffrey R; Regnier, Michael; Geeves, Michael A; Lehman, William | Biophysical journal. | 2020 Aug 18; | 32730789 | |
| Controlling the SARS-CoV-2 spike glycoprotein conformation. | Henderson, Rory; Edwards, Robert J; Mansouri, Katayoun; Janowska, Katarzyna; Stalls, Victoria; Gobeil, Sophie M C; Kopp, Megan; Li, Dapeng; Parks, Rob; Hsu, Allen L; Borgnia, Mario J; Haynes, Barton F; Acharya, Priyamvada | Nature structural & molecular biology. | 2020 10; | 32699321 | |
| Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. | Liu, Lihong; Wang, Pengfei; Nair, Manoj S; Yu, Jian; Rapp, Micah; Wang, Qian; Luo, Yang; Chan, Jasper F-W; Sahi, Vincent; Figueroa, Amir; Guo, Xinzheng V; Cerutti, Gabriele; Bimela, Jude; Gorman, Jason; Zhou, Tongqing; Chen, Zhiwei; Yuen, Kwok-Yung; Kwong | Nature. | 2020 08; | 32698192 | |
| Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication. | Unchwaniwala, Nuruddin; Zhan, Hong; Pennington, Janice; Horswill, Mark; den Boon, Johan A; Ahlquist, Paul | Proceedings of the National Academy of Sciences of the United States of America. | 2020 08 04; | 32690711 | |
| Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex. | Chen, James; Malone, Brandon; Llewellyn, Eliza; Grasso, Michael; Shelton, Patrick M M; Olinares, Paul Dominic B; Maruthi, Kashyap; Eng, Ed; Vatandaslar, Hasan; Chait, Brian T; Kapoor, Tarun; Darst, Seth A; Campbell, Elizabeth A | bioRxiv : the preprint server for biology. | 2020 Jul 13; | 32676607 | |
| Chemical and structural investigation of the paroxetine-human serotonin transporter complex. | Coleman, Jonathan A; Navratna, Vikas; Antermite, Daniele; Yang, Dongxue; Bull, James A; Gouaux, Eric | eLife. | 2020 Jul 03; | 32618269 | |
| Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis. | Herrera, Natalia G; Morano, Nicholas C; Celikgil, Alev; Georgiev, George I; Malonis, Ryan J; Lee, James H; Tong, Karen; Vergnolle, Olivia; Massimi, Aldo B; Yen, Laura Y; Noble, Alex J; Kopylov, Mykhailo; Bonanno, Jeffrey B; Garrett-Thomson, Sarah C; Hayes, David B; Bortz 3rd, Robert H; Wirchnianski, Ariel S; Florez, Catalina; Laudermilch, Ethan; Haslwanter, Denise; Fels, J Maximilian; Dieterle, M Eugenia; Jangra, Rohit K; Barnhill, Jason; Mengotto, Amanda; Kimmel, Duncan; Daily, Johanna P; Pirofski, Liise-Anne; Chandran, Kartik; Brenowitz, Michael; Garforth, Scott J; Eng, Edward T; Lai, Jonathan R; Almo, Steven C | bioRxiv : the preprint server for biology | 2020 Jun 17 | 32587972 | |
| Controlling the SARS-CoV-2 Spike Glycoprotein Conformation. | Henderson, Rory; Edwards, Robert J; Mansouri, Katayoun; Janowska, Katarzyna; Stalls, Victoria; Gobeil, Sophie; Kopp, Megan; Hsu, Allen; Borgnia, Mario; Parks, Rob; Haynes, Barton F; Acharya, Priyamvada | bioRxiv : the preprint server for biology. | 2020 May 18; | 32511343 | |
| The His-Gly motif of acid-sensing ion channels resides in a reentrant 'loop' implicated in gating and ion selectivity. | Yoder, Nate; Gouaux, Eric | eLife | 2020 06 04 | 32496192 | |
| Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. | Zheng, Xiangdong; Fu, Ziao; Su, Deyuan; Zhang, Yuebin; Li, Minghui; Pan, Yaping; Li, Huan; Li, Shufang; Grassucci, Robert A; Ren, Zhenning; Hu, Zhengshan; Li, Xueming; Zhou, Ming; Li, Guohui; Frank, Joachim; Yang, Jian | Nature structural & molecular biology. | 2020 07; | 32483338 | |
| Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch. | Sobti, Meghna; Walshe, James L; Wu, Di; Ishmukhametov, Robert; Zeng, Yi C; Robinson, Carol V; Berry, Richard M; Stewart, Alastair G | Nature communications. | 2020 May 26; | 32457314 | |
| Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery. | Eygeris, Yulia; Patel, Siddharth; Jozic, Antony; Sahay, Gaurav | Nano letters. | 2020 06 10; | 32375002 | |
| Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain. | Vien, Thuy N; Wang, Jinliang; Ng, Leo C T; Cao, Erhu; DeCaen, Paul G | Proceedings of the National Academy of Sciences of the United States of America. | 2020 May 12; | 32332171 | |
| Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins. | Rahman, Md Mahfuzur; Teng, Jinfeng; Worrell, Brady T; Noviello, Colleen M; Lee, Myeongseon; Karlin, Arthur; Stowell, Michael H B; Hibbs, Ryan E | Neuron. | 2020 06 17; | 32275860 | |
| Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy. | Yang, Xiaoyong; Wang, Qinzhe; Cao, Erhu | Nature communications. | 2020 Feb 21; | 32081947 | |
| Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. | Patel, Avinash B; Moore, Camille M; Greber, Basil J; Luo, Jie; Zukin, Stefan A; Ranish, Jeff; Nogales, Eva | eLife | 2019 12 30 | 31886770 | |
| The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. | Gestaut, Daniel; Roh, Soung Hun; Ma, Boxue; Pintilie, Grigore; Joachimiak, Lukasz A; Leitner, Alexander; Walzthoeni, Thomas; Aebersold, Ruedi; Chiu, Wah; Frydman, Judith | Cell. | 2019 Apr 18; | 30955883 |