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Metabolomics (336)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
An obligatory role for neurotensin in high-fat-diet-induced obesity.Li, Jing; Song, Jun; Zaytseva, Yekaterina Y; Liu, Yajuan; Rychahou, Piotr; Jiang, Kai; Starr, Marlene E; Kim, Ji Tae; Harris, Jennifer W; Yiannikouris, Frederique B; Katz, Wendy S; Nilsson, Peter M; Orho-Melander, Marju; Chen, Jing; Zhu, Haining; Fahrenholz, Timothy; Higashi, Richard M; Gao, Tianyan; Morris, Andrew J; Cassis, Lisa A; Fan, Teresa W-M; Weiss, Heidi L; Dobner, Paul R; Melander, Olle; Jia, Jianhang; Evers, B MarkNature2016 May 1927193687
Greazy: Open-Source Software for Automated Phospholipid Tandem Mass Spectrometry Identification.Kochen, Michael A; Chambers, Matthew C; Holman, Jay D; Nesvizhskii, Alexey I; Weintraub, Susan T; Belisle, John T; Islam, M Nurul; Griss, Johannes; Tabb, David LAnalytical chemistry2016 May 2427186799
Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract.Winston, Jenessa A; Theriot, Casey MAnaerobe2016 May 727163871
Hyperglucagonemia Mitigates the Effect of Metformin on Glucose Production in Prediabetes.Konopka, Adam R; Esponda, Raul Ruiz; Robinson, Matthew M; Johnson, Matthew L; Carter, Rickey E; Schiavon, Michele; Cobelli, Claudio; Wondisford, Fredric E; Lanza, Ian R; Nair, K SreekumaranCell reports2016 May 1727160898
Stable Isotope Resolved Metabolomics Studies in Ex Vivo TIssue Slices.Fan, Teresa W-M; Lane, Andrew N; Higashi, Richard MBio-protocol2016 Feb 527158639
Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer.Wang, Weimin; Kryczek, Ilona; Dost�l, Lubom�r; Lin, Heng; Tan, Lijun; Zhao, Lili; Lu, Fujia; Wei, Shuang; Maj, Tomasz; Peng, Dongjun; He, Gong; Vatan, Linda; Szeliga, Wojciech; Kuick, Rork; Kotarski, Jan; Tarkowski, Rafa?; Dou, Yali; Rattan, Ramandeep; Munkarah, Adnan; Liu, J Rebecca; Zou, WeipingCell2016 May 1927133165
Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure.Nording, Malin L; Yang, Jun; Hoang, Laura; Zamora, Vanessa; Uyeminami, Dale; Espiritu, Imelda; Pinkerton, Kent E; Hammock, Bruce D; Luria, AyalaJournal of metabolomics2015 Apr27076918
Metabolomics by Gas Chromatography-Mass Spectrometry: Combined Targeted and Untargeted Profiling.Fiehn, OliverCurrent protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]27038389
(1)H NMR Metabolomics Study of Spleen from C57BL/6 Mice Exposed to Gamma Radiation.Xiao, X; Hu, M; Liu, M; Hu, J ZMetabolomics : open access27019763
Association of urinary metabolites with radiographic progression of knee osteoarthritis in overweight and obese adults: an exploratory study.Loeser, R F; Pathmasiri, W; Sumner, S J; McRitchie, S; Beavers, D; Saxena, P; Nicklas, B J; Jordan, J; Guermazi, A; Hunter, D J; Messier, S POsteoarthritis and cartilage / OARS, Osteoarthritis Research Society2016 Mar 2127012755
Mass spectrometry-based monitoring of millisecond protein-ligand binding dynamics using an automated microfluidic platform.Cong, Yongzheng; Katipamula, Shanta; Trader, Cameron D; Orton, Daniel J; Geng, Tao; Baker, Erin S; Kelly, Ryan TLab on a chip2016 Apr 2627009517
Urinary proteomics and metabolomics studies to monitor bladder health and urological diseases.Chen, Zhaohui; Kim, JayoungBMC urology27000794
Applications of NMR spectroscopy to systems biochemistry.Fan, Teresa W-M; Lane, Andrew NProgress in nuclear magnetic resonance spectroscopy2016 Feb26952191
Bar Coding MS(2) Spectra for Metabolite Identification.Spalding, Jonathan L; Cho, Kevin; Mahieu, Nathaniel G; Nikolskiy, Igor; Llufrio, Elizabeth M; Johnson, Stephen L; Patti, Gary JAnalytical chemistry2016 Mar 126837423
Impact of Long-Term Poor and Good Glycemic Control on Metabolomics Alterations in Type 1 Diabetic People.Dutta, Tumpa; Kudva, Yogish C; Persson, Xuan-Mai T; Schenck, Louis A; Ford, G Charles; Singh, Ravinder J; Carter, Rickey; Nair, K SreekumaranThe Journal of clinical endocrinology and metabolism2016 Mar26796761
A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation.Viader, Andreu; Ogasawara, Daisuke; Joslyn, Christopher M; Sanchez-Alavez, Manuel; Mori, Simone; Nguyen, William; Conti, Bruno; Cravatt, Benjamin FeLife.2016;26779719
Metabolomic Profiling of Arginine Metabolome Links Altered Methylation to Chronic Kidney Disease Accelerated Atherosclerosis.Mathew, Anna V; Zeng, Lixia; Byun, Jaeman; Pennathur, SubramaniamJournal of proteomics & bioinformatics.2015 Oct;26778898
Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease.Sas, Kelli M; Nair, Viji; Byun, Jaeman; Kayampilly, Pradeep; Zhang, Hongyu; Saha, Jharna; Brosius 3rd, Frank C; Kretzler, Matthias; Pennathur, SubramaniamJournal of proteomics & bioinformatics.2015 Oct;26778897
Dicer1 mediated miRNA processing shapes the mRNA profile and function of murine platelets.Rowley, Jesse W; Chappaz, Stéphane; Corduan, Aurélie; Chong, Mark M W; Campbell, Robert; Khoury, Amanda; Manne, Bhanu Kanth; Wurtzel, Jeremy G T; Michael, James V; Goldfinger, Lawrence E; Mumaw, Michele M; Nieman, Marvin T; Kile, Benjamin T; Provost, Patrick; Weyrich, Andrew SBlood.2016 Jan 14;26773046
Uncovering biologically significant lipid isomers with liquid chromatography, ion mobility spectrometry and mass spectrometry.Kyle, Jennifer E; Zhang, Xing; Weitz, Karl K; Monroe, Matthew E; Ibrahim, Yehia M; Moore, Ronald J; Cha, Jeeyeon; Sun, Xiaofei; Lovelace, Erica S; Wagoner, Jessica; Polyak, Stephen J; Metz, Thomas O; Dey, Sudhansu K; Smith, Richard D; Burnum-Johnson, Kristin E; Baker, Erin SThe Analyst2016 Feb 1526734689
SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery.Saxena, Neetu; Maio, Nunziata; Crooks, Daniel R; Ricketts, Christopher J; Yang, Youfeng; Wei, Ming-Hui; Fan, Teresa W-M; Lane, Andrew N; Sourbier, Carole; Singh, Anamika; Killian, J Keith; Meltzer, Paul S; Vocke, Cathy D; Rouault, Tracey A; Linehan, W MarstonJournal of the National Cancer Institute.2016 Jan;26719882
Altered Skeletal Muscle Mitochondrial Proteome As the Basis of Disruption of Mitochondrial Function in Diabetic Mice.Zabielski, Piotr; Lanza, Ian R; Gopala, Srinivas; Holtz Heppelmann, Carrie J; Bergen 3rd, H Robert; Dasari, Surendra; Nair, K SreekumaranDiabetes2016 Mar26718503
Predictors of Whole-Body Insulin Sensitivity Across Ages and Adiposity in Adult Humans.Lalia, Antigoni Z; Dasari, Surendra; Johnson, Matthew L; Robinson, Matthew M; Konopka, Adam R; Distelmaier, Klaus; Port, John D; Glavin, Maria T; Esponda, Raul Ruiz; Nair, K Sreekumaran; Lanza, Ian RThe Journal of clinical endocrinology and metabolism2016 Feb26709968
Ultrafast Polyphenol Metabolomics of Red Wines Using MicroLC-MS/MS.Ma, Yan; Tanaka, Nobuo; Vaniya, Arpana; Kind, Tobias; Fiehn, OliverJournal of agricultural and food chemistry2016 Jan 2026698107
Antioxidant Drug Tempol Promotes Functional Metabolic Changes in the Gut Microbiota.Cai, Jingwei; Zhang, Limin; Jones, Richard A; Correll, Jared B; Hatzakis, Emmanuel; Smith, Philip B; Gonzalez, Frank J; Patterson, Andrew DJournal of proteome research2016 Feb 526696396
(13)C Tracer Studies of Metabolism in Mouse Tumor Xenografts.Lane, Andrew N; Yan, Jun; Fan, Teresa W-MBio-protocol.2015 Nov 20;26693168
A roadmap for the XCMS family of software solutions in metabolomics.Mahieu, Nathaniel G; Genenbacher, Jessica Lloyd; Patti, Gary JCurrent opinion in chemical biology.2016 Feb;87-9326673825
Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction.Jiang, Changtao; Xie, Cen; Lv, Ying; Li, Jing; Krausz, Kristopher W; Shi, Jingmin; Brocker, Chad N; Desai, Dhimant; Amin, Shantu G; Bisson, William H; Liu, Yulan; Gavrilova, Oksana; Patterson, Andrew D; Gonzalez, Frank JNature communications26670557
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.Ogasawara, Daisuke; Deng, Hui; Viader, Andreu; Baggelaar, Marc P; Breman, Arjen; den Dulk, Hans; van den Nieuwendijk, Adriann M C H; Soethoudt, Marjolein; van der Wel, Tom; Zhou, Juan; Overkleeft, Herman S; Sanchez-Alavez, Manuel; Mo, Simone; Nguyen, William; Conti, Bruno; Liu, Xiaojie; Chen, Yao; Liu, Qing-Song; Cravatt, Benjamin F; van der Stelt, MarioProceedings of the National Academy of Sciences of the United States of America2016 Jan 526668358
Toward Merging Untargeted and Targeted Methods in Mass Spectrometry-Based Metabolomics and Lipidomics.Cajka, Tomas; Fiehn, OliverAnalytical chemistry2016 Jan 526637011
Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1?-dependent manner.Kakazu, Eiji; Mauer, Amy S; Yin, Meng; Malhi, HarmeetJournal of lipid research2016 Feb26621917
Virus encoded circulatory miRNAs for early detection of prostate cancer.Kim, Jayoung; Yun, Seok Joong; Kim, Wun-JaeBMC urology.2015;11626612689
Metabolite Signatures in Hydrophilic Extracts of Mouse Lungs Exposed to Cigarette Smoke Revealed by (1)H NMR Metabolomics Investigation.Jz, Hu; X, Wang; J, Feng; Bj, Robertson; Km, Waters; Sc, Tilton; Jg, Pounds; Ra, Corley; M, Liu; M, HuMetabolomics : open access.2015 Jun;26609465
Nanoparticle-Assisted Removal of Protein in Human Serum for Metabolomics Studies.Zhang, Bo; Xie, Mouzhe; Bruschweiler-Li, Lei; Br�schweiler, RafaelAnalytical chemistry2016 Jan 526605638
Ion Mobility in Clinical Analysis: Current Progress and Future Perspectives.Chouinard, Christopher D; Wei, Michael S; Beekman, Christopher R; Kemperman, Robin H J; Yost, Richard AClinical chemistry2016 Jan26585928
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.Sperber, Henrik; Mathieu, Julie; Wang, Yuliang; Ferreccio, Amy; Hesson, Jennifer; Xu, Zhuojin; Fischer, Karin A; Devi, Arikketh; Detraux, Damien; Gu, Haiwei; Battle, Stephanie L; Showalter, Megan; Valensisi, Cristina; Bielas, Jason H; Ericson, Nolan G; Margaretha, Lilyana; Robitaille, Aaron M; Margineantu, Daciana; Fiehn, Oliver; Hockenbery, David; Blau, C Anthony; Raftery, Daniel; Margolin, Adam A; Hawkins, R David; Moon, Randall T; Ware, Carol B; Ruohola-Baker, HanneleNature cell biology2015 Dec26571212
Altered fecal short chain fatty acid composition in children with a history of Hirschsprung-associated enterocolitis.Demehri, Farokh R; Frykman, Philip K; Cheng, Zhi; Ruan, Chunhai; Wester, Tomas; Nordenskj�ld, Agneta; Kawaguchi, Akemi; Hui, Thomas T; Granstr�m, Anna L; Funari, Vince; Teitelbaum, Daniel H; HAEC Collaborative Research GroupJournal of pediatric surgery2016 Jan26561246
Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity.Ma, Siming; Lee, Sang-Goo; Kim, Eun Bae; Park, Thomas J; Seluanov, Andrei; Gorbunova, Vera; Buffenstein, Rochelle; Seravalli, Javier; Gladyshev, Vadim NCell reports.2015 Nov 17;1319-2626549444
Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.Singh, Vishal; Chassaing, Benoit; Zhang, Limin; San Yeoh, Beng; Xiao, Xia; Kumar, Manish; Baker, Mark T; Cai, Jingwei; Walker, Rachel; Borkowski, Kamil; Harvatine, Kevin J; Singh, Nagendra; Shearer, Gregory C; Ntambi, James M; Joe, Bina; Patterson, Andrew D; Gewirtz, Andrew T; Vijay-Kumar, MatamCell metabolism2015 Dec 126525535
Altered Metabolic Profile With Sodium-Restricted Dietary Approaches to Stop Hypertension Diet in Hypertensive Heart Failure With Preserved Ejection Fraction.Mathew, Anna V; Seymour, E Mitchell; Byun, Jaeman; Pennathur, Subramaniam; Hummel, Scott LJournal of cardiac failure2015 Dec26497755
Interactions Between the Gastrointestinal Microbiome and Clostridium difficile.Theriot, Casey M; Young, Vincent BAnnual review of microbiology.2015;445-6126488281
Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools.Sud M1, Fahy E1, Cotter D1, Azam K1, Vadivelu I1, Burant C2, Edison A3, Fiehn O4, Higashi R5, Nair KS6, Sumner S7, Subramaniam S8.Nucleic Acids Research2015 Oct 1326467476
Dectin-1 Activation by a Natural Product ?-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype.Liu, Min; Luo, Fengling; Ding, Chuanlin; Albeituni, Sabrin; Hu, Xiaoling; Ma, Yunfeng; Cai, Yihua; McNally, Lacey; Sanders, Mary Ann; Jain, Dharamvir; Kloecker, Goetz; Bousamra 2nd, Michael; Zhang, Huang-ge; Higashi, Richard M; Lane, Andrew N; Fan, Teresa W-M; Yan, JunJournal of immunology (Baltimore, Md. : 1950)2015 Nov 1526453753
The balance of powers: Redox regulation of fibrogenic pathways in kidney injury.Okamura, Daryl M; Pennathur, SubramaniamRedox biology.2015 Dec;495-50426448394
AMPK Protects Leukemia-Initiating Cells in Myeloid Leukemias from Metabolic Stress in the Bone Marrow.Saito, Yusuke; Chapple, Richard H; Lin, Angelique; Kitano, Ayumi; Nakada, DaisukeCell stem cell.2015 Nov 5;585-9626440282
Warpgroup: increased precision of metabolomic data processing by consensus integration bound analysis.Mahieu, Nathaniel G; Spalding, Jonathan L; Patti, Gary JBioinformatics (Oxford, England)2016 Jan 1526424859
Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism.Gooding, Jessica R; Jensen, Mette V; Dai, Xiaoqing; Wenner, Brett R; Lu, Danhong; Arumugam, Ramamani; Ferdaoussi, Mourad; MacDonald, Patrick E; Newgard, Christopher BCell reports.2015 Oct 6;157-6726411681
Liquid Chromatography-Mass Spectrometry Metabolic and Lipidomic Sample Preparation Workflow for Suspension-Cultured Mammalian Cells using Jurkat T lymphocyte Cells.Ulmer, Candice Z; Yost, Richard A; Chen, Jing; Mathews, Clayton E; Garrett, Timothy JJournal of proteomics & bioinformatics.2015 Jun;126-13226401069
The ubiquitin ligase Siah2 regulates obesity-induced adipose tissue inflammation.Kilroy, Gail; Carter, Lauren E; Newman, Susan; Burk, David H; Manuel, Justin; Möller, Andreas; Bowtell, David D; Mynatt, Randall L; Ghosh, Sujoy; Floyd, Z ElizabethObesity (Silver Spring, Md.).2015 Sep 18;26380945
Decline of Phosphotransfer and Substrate Supply Metabolic Circuits Hinders ATP Cycling in Aging Myocardium.Nemutlu, Emirhan; Gupta, Anu; Zhang, Song; Viqar, Maria; Holmuhamedov, Ekhson; Terzic, Andre; Jahangir, Arshad; Dzeja, PetrasPloS one.2015;e013655626378442
Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.Guo, Yanhong; Fan, Yanbo; Zhang, Jifeng; Lomberk, Gwen A; Zhou, Zhou; Sun, Lijie; Mathison, Angela J; Garcia-Barrio, Minerva T; Zhang, Ji; Zeng, Lixia; Li, Lei; Pennathur, Subramaniam; Willer, Cristen J; Rader, Daniel J; Urrutia, Raul; Chen, Y EugeneThe Journal of clinical investigation.2015 Oct 1;3819-3026368306
Vitamin D in Tear Fluid.Lu, Xiaowen; Elizondo, Rodolfo A; Nielsen, Rikke; Christensen, Erik I; Yang, Jun; Hammock, Bruce D; Watsky, Mitchell AInvestigative ophthalmology & visual science.2015 Sep;5880-726348637
Comparison of blood plasma sample preparation methods for combined LC-MS lipidomics and metabolomics.Patterson, Rainey E; Ducrocq, Antoine J; McDougall, Danielle J; Garrett, Timothy J; Yost, Richard AJournal of chromatography. B, Analytical technologies in the biomedical and life sciences.2015 Oct 1;260-626343017
Mechanism by Which Caloric Restriction Improves Insulin Sensitivity in Sedentary Obese Adults.Johnson, Matthew L; Distelmaier, Klaus; Lanza, Ian R; Irving, Brian A; Robinson, Matthew M; Konopka, Adam R; Shulman, Gerald I; Nair, K SreekumaranDiabetes.2016 Jan;74-8426324180
Differential N-Glycosylation Patterns in Lung Adenocarcinoma Tissue.Ruhaak, L Renee; Taylor, Sandra L; Stroble, Carol; Nguyen, Uyen Thao; Parker, Evan A; Song, Ting; Lebrilla, Carlito B; Rom, William N; Pass, Harvey; Kim, Kyoungmi; Kelly, Karen; Miyamoto, SuzanneJournal of proteome research.2015 Nov 6;4538-4926322380
Mitochondrial Aging and Physical Decline: Insights From Three Generations of Women.Hebert, Sadie L; Marquet-de Rougé, Perrine; Lanza, Ian R; McCrady-Spitzer, Shelly K; Levine, James A; Middha, Sumit; Carter, Rickey E; Klaus, Katherine A; Therneau, Terry M; Highsmith, Edward W; Nair, K SreekumaranThe journals of gerontology. Series A, Biological sciences and medical sciences.2015 Nov;1409-1726297939
Retention projection enables accurate calculation of liquid chromatographic retention times across labs and methods.Abate-Pella, Daniel; Freund, Dana M; Ma, Yan; Simón-Manso, Yamil; Hollender, Juliane; Broeckling, Corey D; Huhman, David V; Krokhin, Oleg V; Stoll, Dwight R; Hegeman, Adrian D; Kind, Tobias; Fiehn, Oliver; Schymanski, Emma L; Prenni, Jessica E; Sumner, Lloyd W; Boswell, Paul GJournal of chromatography. A.2015 Sep 18;43-5126292625
Monoacylglycerol Lipase Regulates Fever Response.Sanchez-Alavez, Manuel; Nguyen, William; Mori, Simone; Moroncini, Gianluca; Viader, Andreu; Nomura, Daniel K; Cravatt, Benjamin F; Conti, BrunoPloS one.2015;e013443726287872
Dynamic Metabolite Profiling in an Archaeon Connects Transcriptional Regulation to Metabolic Consequences.Todor, Horia; Gooding, Jessica; Ilkayeva, Olga R; Schmid, Amy KPloS one.2015;e013569326284786
Diacetylspermine Is a Novel Prediagnostic Serum Biomarker for Non-Small-Cell Lung Cancer and Has Additive Performance With Pro-Surfactant Protein B.Wikoff, William R; Hanash, Samir; DeFelice, Brian; Miyamoto, Suzanne; Barnett, Matt; Zhao, Yang; Goodman, Gary; Feng, Ziding; Gandara, David; Fiehn, Oliver; Taguchi, AyumuJournal of clinical oncology : official journal of the American Society of Clinical Oncology.2015 Nov 20;3880-626282655
Investigation of metabolomic blood biomarkers for detection of adenocarcinoma lung cancer.Fahrmann, Johannes F; Kim, Kyoungmi; DeFelice, Brian C; Taylor, Sandra L; Gandara, David R; Yoneda, Ken Y; Cooke, David T; Fiehn, Oliver; Kelly, Karen; Miyamoto, SuzanneCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.2015 Nov;1716-2326282632
Profiling the metabolome changes caused by cranberry procyanidins in plasma of female rats using (1) H NMR and UHPLC-Q-Orbitrap-HRMS global metabolomics approaches.Liu, Haiyan; Garrett, Timothy J; Tayyari, Fariba; Gu, LiweiMolecular nutrition & food research.2015 Nov;2107-1826264887
Assess the expression of ubiquitin specific protease USP2a for bladder cancer diagnosis.Jeong, Pildu; Ha, Yun-Sok; Yun, Seok-Joong; Yoon, Hyung Yoon; Freeman, Michael R; Kim, Jayoung; Kim, Wun-JaeBMC urology.2015 Aug 7;8026250800
Metastatic Melanoma Induced Metabolic Changes in C57BL/6J Mouse Stomach Measured by 1H NMR Spectroscopy.Wang, X; Hu, M; Liu, M; Hu, J ZMetabolomics : open access.2014;26246958
Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity.Ma, Siming; Yim, Sun Hee; Lee, Sang-Goo; Kim, Eun Bae; Lee, Sang-Rae; Chang, Kyu-Tae; Buffenstein, Rochelle; Lewis, Kaitlyn N; Park, Thomas J; Miller, Richard A; Clish, Clary B; Gladyshev, Vadim NCell metabolism.2015 Aug 4;332-4326244935
Plasma linoleic acid partially mediates the association of bipolar disorder on self-reported mental health scales.Evans, Simon J; Assari, Shervin; Harrington, Gloria J; Chang, Ya-Wen; Burant, Charles F; McInnis, Melvin GJournal of psychiatric research.2015 Sep;61-726228402
Dietary DHA reduces downstream endocannabinoid and inflammatory gene expression and epididymal fat mass while improving aspects of glucose use in muscle in C57BL/6J mice.Kim, J; Carlson, M E; Kuchel, G A; Newman, J W; Watkins, B AInternational journal of obesity (2005)2016 Jan26219414
Using fragmentation trees and mass spectral trees for identifying unknown compounds in metabolomics.Vaniya, Arpana; Fiehn, OliverTrends in analytical chemistry : TRAC.2015 Jun 1;52-6126213431
Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.Viader, Andreu; Blankman, Jacqueline L; Zhong, Peng; Liu, Xiaojie; Schlosburg, Joel E; Joslyn, Christopher M; Liu, Qing-Song; Tomarchio, Aaron J; Lichtman, Aron H; Selley, Dana E; Sim-Selley, Laura J; Cravatt, Benjamin FCell reports.2015 Aug 4;798-80826212325
Temporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures.Meissen, John K; Hirahatake, Kristin M; Adams, Sean H; Fiehn, OliverMetabolomics : Official journal of the Metabolomic Society.2015 Jun 1;707-72126190955
Development of a New Ion Mobility (Quadrupole) Time-of-Flight Mass Spectrometer.Ibrahim, Yehia M; Baker, Erin S; Danielson 3rd, William F; Norheim, Randolph V; Prior, David C; Anderson, Gordon A; Belov, Mikhail E; Smith, Richard DInternational journal of mass spectrometry.2015 Feb 1;655-66226185483
Sealed rotors for in situ high temperature high pressure MAS NMR.Hu, Jian Zhi; Hu, Mary Y; Zhao, Zhenchao; Xu, Suochang; Vjunov, Aleksei; Shi, Hui; Camaioni, Donald M; Peden, Charles H F; Lercher, Johannes AChemical communications (Cambridge, England).2015 Aug 18;13458-6126171928
Fecal Microbiota Transplantation Eliminates Clostridium difficile in a Murine Model of Relapsing Disease.Seekatz, Anna M; Theriot, Casey M; Molloy, Caitlyn T; Wozniak, Katherine L; Bergin, Ingrid L; Young, Vincent BInfection and immunity2015 Oct26169276
Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare study.Liesenfeld, David B; Grapov, Dmitry; Fahrmann, Johannes F; Salou, Mariam; Scherer, Dominique; Toth, Reka; Habermann, Nina; Böhm, Jürgen; Schrotz-King, Petra; Gigic, Biljana; Schneider, Martin; Ulrich, Alexis; Herpel, Esther; Schirmacher, Peter; Fiehn, Oliver; Lampe, Johanna W; Ulrich, Cornelia MThe American journal of clinical nutrition.2015 Aug;433-4326156741
Two elephants in the room: new hybrid nuclear magnetic resonance and mass spectrometry approaches for metabolomics.Bingol, Kerem; Brüschweiler, RafaelCurrent opinion in clinical nutrition and metabolic care.2015 Sep;471-726154280
Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise.Seiler, Sarah E; Koves, Timothy R; Gooding, Jessica R; Wong, Kari E; Stevens, Robert D; Ilkayeva, Olga R; Wittmann, April H; DeBalsi, Karen L; Davies, Michael N; Lindeboom, Lucas; Schrauwen, Patrick; Schrauwen-Hinderling, Vera B; Muoio, Deborah MCell metabolism2015 Jul 726154055
Gene expression changes in subcutaneous adipose tissue due to Cushing's disease.Hochberg, Irit; Harvey, Innocence; Tran, Quynh T; Stephenson, Erin J; Barkan, Ariel L; Saltiel, Alan R; Chandler, William F; Bridges, DaveJournal of molecular endocrinology.2015 Oct;81-9426150553
Metabolomics and Natural-Products Strategies to Study Chemical Ecology in Nematodes.Edison, Arthur S; Clendinen, Chaevien S; Ajredini, Ramadan; Beecher, Chris; Ponce, Francesca V; Stupp, Gregory SIntegrative and comparative biology.2015 Sep;478-8526141866
Enhancing biological analyses with three dimensional field asymmetric ion mobility, low field drift tube ion mobility and mass spectrometry (?FAIMS/IMS-MS) separations.Zhang, Xing; Ibrahim, Yehia M; Chen, Tsung-Chi; Kyle, Jennifer E; Norheim, Randolph V; Monroe, Matthew E; Smith, Richard D; Baker, Erin SThe Analyst.2015 Sep 28;6955-6326140287
Metabolomics applied to the pancreatic islet.Gooding, Jessica R; Jensen, Mette V; Newgard, Christopher BArchives of biochemistry and biophysics.2015 Jun 25;26116790
Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways.Mitsche, Matthew A; McDonald, Jeffrey G; Hobbs, Helen H; Cohen, Jonathan CeLife.2015 Jun 26;e0799926114596
Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.Gao, Lu; Rabbitt, Elizabeth H; Condon, Jennifer C; Renthal, Nora E; Johnston, John M; Mitsche, Matthew A; Chambon, Pierre; Xu, Jianming; O'Malley, Bert W; Mendelson, Carole RThe Journal of clinical investigation.2015 Jul 1;2808-2426098214
Gene Expression Signature in Adipose Tissue of Acromegaly Patients.Hochberg, Irit; Tran, Quynh T; Barkan, Ariel L; Saltiel, Alan R; Chandler, William F; Bridges, DavePloS one.2015 Jun 18;e012935926087292
Use of Charged Nanoparticles in NMR-Based Metabolomics for Spectral Simplification and Improved Metabolite Identification.Zhang, Bo; Xie, Mouzhe; Bruschweiler-Li, Lei; Bingol, Kerem; Brüschweiler, RafaelAnalytical chemistry.2015 Jul 21;7211-726087125
Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease.Zhang, Liang; Zhang, Song; Maezawa, Izumi; Trushin, Sergey; Minhas, Paras; Pinto, Matthew; Jin, Lee-Way; Prasain, Keshar; Nguyen, Thi D T; Yamazaki, Yu; Kanekiyo, Takahisa; Bu, Guojun; Gateno, Benjamin; Chang, Kyeong-Ok; Nath, Karl A; Nemutlu, Emirhan; Dzeja, Petras; Pang, Yuan-Ping; Hua, Duy H; Trushina, EugeniaEBioMedicine.2015 Apr 1;294-30526086035
Distribution and biomarker of carbon-14 labeled fullerene C60 ([(14) C(U)]C60 ) in pregnant and lactating rats and their offspring after maternal intravenous exposure.Snyder, Rodney W; Fennell, Timothy R; Wingard, Christopher J; Mortensen, Ninell P; Holland, Nathan A; Shannahan, Jonathan H; Pathmasiri, Wimal; Lewin, Anita H; Sumner, Susan C JJournal of applied toxicology : JAT.2015 Dec;1438-5126081520
Cross-talk between branched-chain amino acids and hepatic mitochondria is compromised in nonalcoholic fatty liver disease.Sunny, Nishanth E; Kalavalapalli, Srilaxmi; Bril, Fernando; Garrett, Timothy J; Nautiyal, Manisha; Mathew, Justin T; Williams, Caroline M; Cusi, KennethAmerican journal of physiology. Endocrinology and metabolism.2015 Aug 15;E311-926058864
Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula.?ervenka, L; Melenovsk�, V; Huskov�, Z; Sporkov�, A; B�rgelov�, M; ?karoupkov�, P; Hwang, S H; Hammock, B D; Imig, J D; Sadowski, JPhysiological research / Academia Scientiarum Bohemoslovaca26047375
Enhancing bottom-up and top-down proteomic measurements with ion mobility separations.Baker, Erin Shammel; Burnum-Johnson, Kristin E; Ibrahim, Yehia M; Orton, Daniel J; Monroe, Matthew E; Kelly, Ryan T; Moore, Ronald J; Zhang, Xing; Théberge, Roger; Costello, Catherine E; Smith, Richard DProteomics.2015 Aug;2766-7626046661
PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.Yoh, Sunnie M; Schneider, Monika; Seifried, Janna; Soonthornvacharin, Stephen; Akleh, Rana E; Olivieri, Kevin C; De Jesus, Paul D; Ruan, Chunhai; de Castro, Elisa; Ruiz, Pedro A; Germanaud, David; des Portes, Vincent; García-Sastre, Adolfo; König, Renate; Chanda, Sumit KCell.2015 Jun 4;1293-30526046437
Infant Maturity at Birth Reveals Minor Differences in the Maternal Milk Metabolome in the First Month of Lactation.Spevacek, Ann R; Smilowitz, Jennifer T; Chin, Elizabeth L; Underwood, Mark A; German, J Bruce; Slupsky, Carolyn MThe Journal of nutrition.2015 Aug;1698-70826041675
Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice.Zhang, Limin; Hatzakis, Emmanuel; Nichols, Robert G; Hao, Ruixin; Correll, Jared; Smith, Philip B; Chiaro, Christopher R; Perdew, Gary H; Patterson, Andrew DEnvironmental science & technology.2015 Jul 7;8067-7726023891
Meta-omics uncover temporal regulation of pathways across oral microbiome genera during in vitro sugar metabolism.Edlund, Anna; Yang, Youngik; Yooseph, Shibu; Hall, Adam P; Nguyen, Don D; Dorrestein, Pieter C; Nelson, Karen E; He, Xuesong; Lux, Renate; Shi, Wenyuan; McLean, Jeffrey SThe ISME journal2015 Dec26023872
Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice.Johnson, Matthew L; Lalia, Antigoni Z; Dasari, Surendra; Pallauf, Maximilian; Fitch, Mark; Hellerstein, Marc K; Lanza, Ian RAging cell.2015 Oct;734-4326010060
A less-biased analysis of metalloproteins reveals novel zinc coordination geometries.Yao, Sen; Flight, Robert M; Rouchka, Eric C; Moseley, Hunter N BProteins.2015 Aug;1470-8726009987
Defining the metabolome: size, flux, and regulation.Zamboni, Nicola; Saghatelian, Alan; Patti, Gary JMolecular cell.2015 May 21;699-70626000853
Epidermal Fatty Acid binding protein promotes skin inflammation induced by high-fat diet.Zhang, Yuwen; Li, Qiang; Rao, Enyu; Sun, Yanwen; Grossmann, Michael E; Morris, Rebecca J; Cleary, Margot P; Li, BingImmunity.2015 May 19;953-6425992864
Hepatic insulin sensitivity in healthy and prediabetic subjects: from a dual- to a single-tracer oral minimal model.Visentin, Roberto; Dalla Man, Chiara; Basu, Rita; Basu, Ananda; Rizza, Robert A; Cobelli, ClaudioAmerican journal of physiology. Endocrinology and metabolism.2015 Jul 15;E161-725991649
Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis.O'Neill, Brian T; Lauritzen, Hans P M M; Hirshman, Michael F; Smyth, Graham; Goodyear, Laurie J; Kahn, C RonaldCell reports.2015 May 26;1220-3525981038
Biochemical association of metabolic profile and microbiome in chronic pressure ulcer wounds.Ammons, Mary Cloud B; Morrissey, Kathryn; Tripet, Brian P; Van Leuven, James T; Han, Anne; Lazarus, Gerald S; Zenilman, Jonathan M; Stewart, Philip S; James, Garth A; Copié, ValériePloS one.2015 May 15;e012673525978400
Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family.Niehaus, Thomas D; Gerdes, Svetlana; Hodge-Hanson, Kelsey; Zhukov, Aleksey; Cooper, Arthur J L; ElBadawi-Sidhu, Mona; Fiehn, Oliver; Downs, Diana M; Hanson, Andrew DBMC genomics.2015 May 15;38225975565
FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.O-Sullivan, InSug; Zhang, Wenwei; Wasserman, David H; Liew, Chong Wee; Liu, Jonathan; Paik, Jihye; DePinho, Ronald A; Stolz, Donna Beer; Kahn, C Ronald; Schwartz, Michael W; Unterman, Terry GNature communications.2015 May 12;707925963540
MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis.Tsugawa, Hiroshi; Cajka, Tomas; Kind, Tobias; Ma, Yan; Higgins, Brendan; Ikeda, Kazutaka; Kanazawa, Mitsuhiro; VanderGheynst, Jean; Fiehn, Oliver; Arita, MasanoriNature methods.2015 Jun;523-625938372
(13)C NMR Metabolomics: INADEQUATE Network Analysis.Clendinen, Chaevien S; Pasquel, Christian; Ajredini, Ramadan; Edison, Arthur SAnalytical chemistry.2015 Jun 2;5698-70625932900
Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus.Cha, Jeeyeon; Burnum-Johnson, Kristin E; Bartos, Amanda; Li, Yingju; Baker, Erin S; Tilton, Susan C; Webb-Robertson, Bobbie-Jo M; Piehowski, Paul D; Monroe, Matthew E; Jegga, Anil G; Murata, Shigeo; Hirota, Yasushi; Dey, Sudhansu KThe Journal of biological chemistry.2015 Jun 12;15337-4925931120
Cardiac resynchronization therapy induces adaptive metabolic transitions in the metabolomic profile of heart failure.Nemutlu, Emirhan; Zhang, Song; Xu, Yi-Zhou; Terzic, Andre; Zhong, Li; Dzeja, Petras D; Cha, Yong-MeiJournal of cardiac failure.2015 Jun;460-925911126
Exercise effects on postprandial glucose metabolism in type 1 diabetes: a triple-tracer approach.Mallad, Ashwini; Hinshaw, Ling; Schiavon, Michele; Dalla Man, Chiara; Dadlani, Vikash; Basu, Rita; Lingineni, Ravi; Cobelli, Claudio; Johnson, Matthew L; Carter, Rickey; Kudva, Yogish C; Basu, AnandaAmerican journal of physiology. Endocrinology and metabolism.2015 Jun 15;E1106-1525898950
Metabolomic Analysis of Oxidative and Glycolytic Skeletal Muscles by Matrix-Assisted Laser Desorption/IonizationMass Spectrometric Imaging (MALDI MSI).Tsai, Yu-Hsuan; Garrett, Timothy J; Carter, Christy S; Yost, Richard AJournal of the American Society for Mass Spectrometry.2015 Jun;915-2325893271
Applications of Multiple Reaction Monitoring to Clinical Glycomics.Ruhaak, L Renee; Lebrilla, Carlito BChromatographia.2015 Mar 1;335-34225892741
Kernel approaches for differential expression analysis of mass spectrometry-based metabolomics data.Zhan, Xiang; Patterson, Andrew D; Ghosh, DebashisBMC bioinformatics.2015 Mar 11;7725887233
Ion Mobility and Tandem Mass Spectrometry of Phosphatidylglycerol and Bis(monoacylglycerol)phosphate (BMP).Hankin, Joseph A; Murphy, Robert C; Barkley, Robert M; Gijón, Miguel AInternational journal of mass spectrometry.2015 Feb 15;255-26325883529
Adipose Tissue Free Fatty Acid Storage In Vivo: Effects of Insulin Versus Niacin as a Control for Suppression of Lipolysis.Ali, Asem H; Mundi, Manpreet; Koutsari, Christina; Bernlohr, David A; Jensen, Michael DDiabetes.2015 Aug;2828-3525883112
NMR/MS Translator for the Enhanced Simultaneous Analysis of Metabolomics Mixtures by NMR Spectroscopy and Mass Spectrometry: Application to Human Urine.Bingol, Kerem; Brüschweiler, RafaelJournal of proteome research.2015 Jun 5;2642-825881480
Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice.Milner, J Justin; Rebeles, Jenny; Dhungana, Suraj; Stewart, Delisha A; Sumner, Susan C J; Meyers, Matthew H; Mancuso, Peter; Beck, Melinda AJournal of immunology (Baltimore, Md. : 1950).2015 May 15;4846-5925862817
Effects of Dietary n-3 Fatty Acids on Hepatic and Peripheral Insulin Sensitivity in Insulin-Resistant Humans.Lalia, Antigoni Z; Johnson, Matthew L; Jensen, Michael D; Hames, Kazanna C; Port, John D; Lanza, Ian RDiabetes care.2015 Jul;1228-3725852206
Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia.Fahrmann, Johannes; Grapov, Dmitry; Yang, Jun; Hammock, Bruce; Fiehn, Oliver; Bell, Graeme I; Hara, ManamiAmerican journal of physiology. Endocrinology and metabolism.2015 Jun 1;E978-8925852003
Profiles of 21-Carbon Steroids in 21-hydroxylase Deficiency.Turcu, Adina F; Rege, Juilee; Chomic, Robert; Liu, Jiayan; Nishimoto, Hiromi K; Else, Tobias; Moraitis, Andreas G; Palapattu, Ganesh S; Rainey, William E; Auchus, Richard JThe Journal of clinical endocrinology and metabolism.2015 Jun;2283-9025850025
MetaMapR: pathway independent metabolomic network analysis incorporating unknowns.Grapov, Dmitry; Wanichthanarak, Kwanjeera; Fiehn, OliverBioinformatics (Oxford, England).2015 Aug 15;2757-6025847005
Melatonin prevents myeloperoxidase heme destruction and the generation of free iron mediated by self-generated hypochlorous acid.Shaeib, Faten; Khan, Sana N; Ali, Iyad; Najafi, Tohid; Maitra, Dhiman; Abdulhamid, Ibrahim; Saed, Ghassan M; Pennathur, Subramaniam; Abu-Soud, Husam MPloS one.2015 Apr 2;e012073725835505
Habitual physical activity and plasma metabolomic patterns distinguish individuals with low vs. high weight loss during controlled energy restriction.Piccolo, Brian D; Keim, Nancy L; Fiehn, Oliver; Adams, Sean H; Van Loan, Marta D; Newman, John WThe Journal of nutrition.2015 Apr;681-9025833772
Application of high-resolution mass spectrometry to measure low abundance isotope enrichment in individual muscle proteins.Hines, Kelly M; Ford, G Charles; Klaus, Katherine A; Irving, Brian A; Ford, Beverly L; Johnson, Kenneth L; Lanza, Ian R; Nair, K SreekumaranAnalytical and bioanalytical chemistry.2015 May;4045-5225832482
Evidence for a link between gut microbiota and hypertension in the Dahl rat.Mell, Blair; Jala, Venkatakrishna R; Mathew, Anna V; Byun, Jaeman; Waghulde, Harshal; Zhang, Youjie; Haribabu, Bodduluri; Vijay-Kumar, Matam; Pennathur, Subramaniam; Joe, BinaPhysiological genomics.2015 Jun;187-9725829393
Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice.Harris, Todd R; Bettaieb, Ahmed; Kodani, Sean; Dong, Hua; Myers, Richard; Chiamvimonvat, Nipavan; Haj, Fawaz G; Hammock, Bruce DToxicology and applied pharmacology.2015 Jul 15;102-1125827057
Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa.Shih, P B; Yang, J; Morisseau, C; German, J B; Zeeland, A A Scott-Van; Armando, A M; Quehenberger, O; Bergen, A W; Magistretti, P; Berrettini, W; Halmi, K A; Schork, N; Hammock, B D; Kaye, WMolecular psychiatry.2015 Mar 31;25824304
Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia.Noetzli, Leila; Lo, Richard W; Lee-Sherick, Alisa B; Callaghan, Michael; Noris, Patrizia; Savoia, Anna; Rajpurkar, Madhvi; Jones, Kenneth; Gowan, Katherine; Balduini, Carlo L; Pecci, Alessandro; Gnan, Chiara; De Rocco, Daniela; Doubek, Michael; Li, Ling; Lu, Lily; Leung, Richard; Landolt-Marticorena, Carolina; Hunger, Stephen; Heller, Paula; Gutierrez-Hartmann, Arthur; Xiayuan, Liang; Pluthero, Fred G; Rowley, Jesse W; Weyrich, Andrew S; Kahr, Walter H A; Porter, Christopher C; Di Paola, JorgeNature genetics.2015 May;535-825807284
Mass Spectrometry Analysis of Pseudomonas aeruginosa Treated with Azithromycin.Phelan, Vanessa V; Fang, Jinshu; Dorrestein, Pieter CJournal of the American Society for Mass Spectrometry.2015 Jun;873-725801585
Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation.Zhang, Limin; Nichols, Robert G; Correll, Jared; Murray, Iain A; Tanaka, Naoki; Smith, Philip B; Hubbard, Troy D; Sebastian, Aswathy; Albert, Istvan; Hatzakis, Emmanuel; Gonzalez, Frank J; Perdew, Gary H; Patterson, Andrew DEnvironmental health perspectives.2015 Jul;679-8825768209
Developmental programming: exposure to testosterone excess disrupts steroidal and metabolic environment in pregnant sheep.Abi Salloum, B; Veiga-Lopez, A; Abbott, D H; Burant, C F; Padmanabhan, VEndocrinology.2015 Jun;2323-3725763641
Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death.Rao, Enyu; Zhang, Yuwen; Zhu, Ganqian; Hao, Jiaqing; Persson, Xuan-Mai T; Egilmez, Nejat K; Suttles, Jill; Li, BingOncotarget.2015 Apr 10;7944-5825760243
Association of UCP-3 rs1626521 with obesity and stomach functions in humans.Acosta, Andres; Camilleri, Michael; Shin, Andrea; Vazquez-Roque, Maria I; Iturrino, Johanna; Lanza, Ian R; Nair, K Sreekumaran; Burton, Duane; O'Neill, Jessica; Eckert, Deborah; Carlson, Paula; Vella, Adrian; Zinsmeister, Alan RObesity (Silver Spring, Md.).2015 Apr;898-90625755013
Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylation.Overmyer, Katherine A; Evans, Charles R; Qi, Nathan R; Minogue, Catherine E; Carson, Joshua J; Chermside-Scabbo, Christopher J; Koch, Lauren G; Britton, Steven L; Pagliarini, David J; Coon, Joshua J; Burant, Charles FCell metabolism.2015 Mar 3;468-7825738461
Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet.Tanaka, Naoki; Takahashi, Shogo; Zhang, Yuan; Krausz, Kristopher W; Smith, Philip B; Patterson, Andrew D; Gonzalez, Frank JBiochimica et biophysica acta.2015 Jul;1242-5225736301
Effect of insulin sensitizer therapy on amino acids and their metabolites.Irving, Brian A; Carter, Rickey E; Soop, Mattias; Weymiller, Audrey; Syed, Husnain; Karakelides, Helen; Bhagra, Sumit; Short, Kevin R; Tatpati, Laura; Barazzoni, Rocco; Nair, K SreekumaranMetabolism: clinical and experimental.2015 Jun;720-825733201
Impact of storage conditions on metabolite profiles of sputum samples from persons with cystic fibrosis.Zhao, Jiangchao; Evans, Charles R; Carmody, Lisa A; LiPuma, John JJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.2015 Jul;468-7325725986
Metabolomics and diabetes: analytical and computational approaches.Sas, Kelli M; Karnovsky, Alla; Michailidis, George; Pennathur, SubramaniamDiabetes.2015 Mar;718-3225713200
Does our gut microbiome predict cardiovascular risk? A review of the evidence from metabolomics.Griffin, Julian L; Wang, Xinzhu; Stanley, ElizabethCirculation. Cardiovascular genetics.2015 Feb;187-9125691688
Discriminating precursors of common fragments for large-scale metabolite profiling by triple quadrupole mass spectrometry.Nikolskiy, Igor; Siuzdak, Gary; Patti, Gary JBioinformatics (Oxford, England).2015 Jun 15;2017-2325691443
Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus.Xu, Jiawen; Morisseau, Christophe; Yang, Jun; Mamatha, Dadala M; Hammock, Bruce DInsect biochemistry and molecular biology.2015 Apr;41-925686802
Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model.Overmyer, Katherine A; Thonusin, Chanisa; Qi, Nathan R; Burant, Charles F; Evans, Charles RPloS one.2015 Feb 6;e011723225658945
Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma.Wikoff, William R; Grapov, Dmitry; Fahrmann, Johannes F; DeFelice, Brian; Rom, William N; Pass, Harvey I; Kim, Kyoungmi; Nguyen, UyenThao; Taylor, Sandra L; Gandara, David R; Kelly, Karen; Fiehn, Oliver; Miyamoto, SuzanneCancer prevention research (Philadelphia, Pa.).2015 May;410-825657018
Gene expression profiling in pachyonychia congenita skin.Cao, Yu-An; Hickerson, Robyn P; Seegmiller, Brandon L; Grapov, Dmitry; Gross, Maren M; Bessette, Marc R; Phinney, Brett S; Flores, Manuel A; Speaker, Tycho J; Vermeulen, Annaleen; Bravo, Albert A; Bruckner, Anna L; Milstone, Leonard M; Schwartz, Mary E; Rice, Robert H; Kaspar, Roger LJournal of dermatological science.2015 Mar;156-6525656049
Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase.Lin, Fengming; Ferguson, Kyle L; Boyer, David R; Lin, Xiaoxia Nina; Marsh, E Neil GACS chemical biology.2015 Apr 17;1137-4425647642
Site-specific glycosylation of secretory immunoglobulin A from human colostrum.Huang, Jincui; Guerrero, Andres; Parker, Evan; Strum, John S; Smilowitz, Jennifer T; German, J Bruce; Lebrilla, Carlito BJournal of proteome research.2015 Mar 6;1335-4925629924
Acute and chronic plasma metabolomic and liver transcriptomic stress effects in a mouse model with features of post-traumatic stress disorder.Gautam, Aarti; D'Arpa, Peter; Donohue, Duncan E; Muhie, Seid; Chakraborty, Nabarun; Luke, Brian T; Grapov, Dmitry; Carroll, Erica E; Meyerhoff, James L; Hammamieh, Rasha; Jett, MartiPloS one.2015 Jan 28;e011709225629821
Regulation of mammalian nucleotide metabolism and biosynthesis.Lane, Andrew N; Fan, Teresa W-MNucleic acids research.2015 Feb 27;2466-8525628363
Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by 1H-detected 15N nuclear magnetic resonance.Lane, Andrew N; Arumugam, Sengodagounder; Lorkiewicz, Pawel K; Higashi, Richard M; Laulhe, Sebastien; Nantz, Michael H; Moseley, Hunter N B; Fan, Teresa W-MMagnetic resonance in chemistry : MRC.2015 May;337-4325616249
Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.Sellers, Katherine; Fox, Matthew P; Bousamra 2nd, Michael; Slone, Stephen P; Higashi, Richard M; Miller, Donald M; Wang, Yali; Yan, Jun; Yuneva, Mariia O; Deshpande, Rahul; Lane, Andrew N; Fan, Teresa W-MThe Journal of clinical investigation.2015 Feb;687-9825607840
Defects in Mitochondrial Efficiency and H2O2 Emissions in Obese Women Are Restored to a Lean Phenotype With Aerobic Exercise Training.Konopka, Adam R; Asante, Albert; Lanza, Ian R; Robinson, Matthew M; Johnson, Matthew L; Dalla Man, Chiara; Cobelli, Claudio; Amols, Mark H; Irving, Brian A; Nair, K SDiabetes.2015 Jun;2104-1525605809
Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis.Zhao, Hong; Chiaro, Christopher R; Zhang, Limin; Smith, Philip B; Chan, Chung Yu; Pedley, Anthony M; Pugh, Raymond J; French, Jarrod B; Patterson, Andrew D; Benkovic, Stephen JThe Journal of biological chemistry.2015 Mar 13;6705-1325605736
Impact of gestational bisphenol A on oxidative stress and free fatty acids: Human association and interspecies animal testing studies.Veiga-Lopez, Almudena; Pennathur, Subramaniam; Kannan, Kurunthachalam; Patisaul, Heather B; Dolinoy, Dana C; Zeng, Lixia; Padmanabhan, VasanthaEndocrinology.2015 Mar;911-2225603046
DIA-Umpire: comprehensive computational framework for data-independent acquisition proteomics.Tsou, Chih-Chiang; Avtonomov, Dmitry; Larsen, Brett; Tucholska, Monika; Choi, Hyungwon; Gingras, Anne-Claude; Nesvizhskii, Alexey INature methods.2015 Mar;258-64, 7 p following 26425599550
Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation.Lee, Jieun; Ellis, Jessica M; Wolfgang, Michael JCell reports.2015 Jan 13;266-7925578732
Aryl hydrocarbon receptor ligands in cancer: friend and foe.Murray, Iain A; Patterson, Andrew D; Perdew, Gary HNature reviews. Cancer.2014 Dec;801-1425568920
Effects of tigecycline and vancomycin administration on established Clostridium difficile infection.Theriot, Casey M; Schumacher, Cassie A; Bassis, Christine M; Seekatz, Anna M; Young, Vincent BAntimicrobial agents and chemotherapy.2015 Mar;1596-60425547352
Dynamics and establishment of Clostridium difficile infection in the murine gastrointestinal tract.Koenigsknecht, Mark J; Theriot, Casey M; Bergin, Ingrid L; Schumacher, Cassie A; Schloss, Patrick D; Young, Vincent BInfection and immunity.2015 Mar;934-4125534943
Circadian variability of insulin sensitivity: physiological input for in silico artificial pancreas.Visentin, Roberto; Dalla Man, Chiara; Kudva, Yogish C; Basu, Ananda; Cobelli, ClaudioDiabetes technology & therapeutics.2015 Jan;4201125531427
High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy.Snowden, Stuart G; Grapov, Dmitry; Settergren, Magnus; D'Alexandri, Fabio Luiz; Haeggstrom, Jesper Z; Fiehn, Oliver; Hyotylainen, Tuulia; Pedersen, Theresa L; Newman, John W; Oresic, Matej; Pernow, John; Wheelock, Craig ECirculation. Cardiovascular genetics.2014 Dec;955-6425516625
Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging.Johnson, Matthew L; Irving, Brian A; Lanza, Ian R; Vendelbo, Mikkel H; Konopka, Adam R; Robinson, Matthew M; Henderson, Gregory C; Klaus, Katherine A; Morse, Dawn M; Heppelmann, Carrie; Bergen 3rd, H Robert; Dasari, Surendra; Schimke, Jill M; Jakaitis, Daniel R; Nair, K SreekumaranThe journals of gerontology. Series A, Biological sciences and medical sciences.2014 Dec 10;25504576
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.Jiang, Changtao; Xie, Cen; Li, Fei; Zhang, Limin; Nichols, Robert G; Krausz, Kristopher W; Cai, Jingwei; Qi, Yunpeng; Fang, Zhong-Ze; Takahashi, Shogo; Tanaka, Naoki; Desai, Dhimant; Amin, Shantu G; Albert, Istvan; Patterson, Andrew D; Gonzalez, Frank JThe Journal of clinical investigation.2015 Jan;386-40225500885
Pharmacometabolomics of l-carnitine treatment response phenotypes in patients with septic shock.Puskarich, Michael A; Finkel, Michael A; Karnovsky, Alla; Jones, Alan E; Trexel, Julie; Harris, Brooke N; Stringer, Kathleen AAnnals of the American Thoracic Society.2015 Jan;46-5625496487
Autonomous metabolomics for rapid metabolite identification in global profiling.Benton, H Paul; Ivanisevic, Julijana; Mahieu, Nathaniel G; Kurczy, Michael E; Johnson, Caroline H; Franco, Lauren; Rinehart, Duane; Valentine, Elizabeth; Gowda, Harsha; Ubhi, Baljit K; Tautenhahn, Ralf; Gieschen, Andrew; Fields, Matthew W; Patti, Gary J; Siuzdak, GaryAnalytical chemistry.2015 Jan 20;884-9125496351
Cardiac steatosis potentiates angiotensin II effects in the heart.Glenn, Denis J; Cardema, Michelle C; Ni, Wei; Zhang, Yan; Yeghiazarians, Yerem; Grapov, Dmitry; Fiehn, Oliver; Gardner, David GAmerican journal of physiology. Heart and circulatory physiology.2015 Feb 15;H339-5025485904
Diet and feeding pattern affect the diurnal dynamics of the gut microbiome.Zarrinpar, Amir; Chaix, Amandine; Yooseph, Shibu; Panda, SatchidanandaCell metabolism.2014 Dec 2;1006-1725470548
Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice.Mazagova, Magdalena; Wang, Lirui; Anfora, Andrew T; Wissmueller, Max; Lesley, Scott A; Miyamoto, Yukiko; Eckmann, Lars; Dhungana, Suraj; Pathmasiri, Wimal; Sumner, Susan; Westwater, Caroline; Brenner, David A; Schnabl, BerndFASEB journal : official publication of the Federation of American Societies for Experimental Biology.2015 Mar;1043-5525466902
Metabolic network motifs can provide novel insights into evolution: The evolutionary origin of Eukaryotic organelles as a case study.Shellman, Erin R; Chen, Yu; Lin, Xiaoxia; Burant, Charles F; Schnell, SantiagoComputational biology and chemistry.2014 Sep 21;242-25025462333
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.Yang, Chendong; Ko, Bookyung; Hensley, Christopher T; Jiang, Lei; Wasti, Ajla T; Kim, Jiyeon; Sudderth, Jessica; Calvaruso, Maria Antonietta; Lumata, Lloyd; Mitsche, Matthew; Rutter, Jared; Merritt, Matthew E; DeBerardinis, Ralph JMolecular cell.2014 Nov 6;414-2425458842
A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis.Frelin, Oceane; Huang, Lili; Hasnain, Ghulam; Jeffryes, James G; Ziemak, Michael J; Rocca, James R; Wang, Bing; Rice, Jennifer; Roje, Sanja; Yurgel, Svetlana N; Gregory 3rd, Jesse F; Edison, Arthur S; Henry, Christopher S; de Crecy-Lagard, Valerie; Hanson, Andrew DThe Biochemical journal.2015 Feb 15;137-4525431972
The need for reflective consideration of an integrative understanding of cardiovascular consequences to PVP formulated C60 exposure.Wingard, Christopher J; Holland, Nathan A; Thompson, Leslie C; Brown, Jared M; Lewin, Anita H; Sumner, Susan J; Fennell, Timothy R; Vidanapathirana, Achini KToxicological sciences : an official journal of the Society of Toxicology.2014 Oct;327-825422842
Top-down analysis of highly post-translationally modified peptides by fourier transform ion cyclotron resonance mass spectrometry.Guerrero, Andres; Lerno, Larry; Barile, Daniela; Lebrilla, Carlito BJournal of the American Society for Mass Spectrometry.2015 Mar;453-925404158
Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice.Bettaieb, Ahmed; Chahed, Samah; Tabet, George; Yang, Jun; Morisseau, Christophe; Griffey, Stephen; Hammock, Bruce D; Haj, Fawaz GPloS one.2014;e11301925402489
The use of metabolomics in population-based research.Su, L Joseph; Fiehn, Oliver; Maruvada, Padma; Moore, Steven C; O'Keefe, Stephen J; Wishart, David S; Zanetti, Krista AAdvances in nutrition (Bethesda, Md.).2014 Nov;785-825398741
(1)H NMR Metabolomics Study of Metastatic Melanoma in C57BL/6J Mouse Spleen.Wang, Xuan; Hu, Mary; Feng, Ju; Liu, Maili; Hu, Jian ZhiMetabolomics : Official journal of the Metabolomic Society.2014 Dec;1129-114425383071
Relative roles of ABCG5/ABCG8 in liver and intestine.Wang, Jin; Mitsche, Matthew A; Lutjohann, Dieter; Cohen, Jonathan C; Xie, Xiao-Song; Hobbs, Helen HJournal of lipid research.2015 Feb;319-3025378657
Identifying individual differences of fluoxetine response in juvenile rhesus monkeys by metabolite profiling.He, Y; Hogrefe, C E; Grapov, D; Palazoglu, M; Fiehn, O; Turck, C W; Golub, M STranslational psychiatry.2014;e47825369145
LC-MS metabolomics of psoriasis patients reveals disease severity-dependent increases in circulating amino acids that are ameliorated by anti-TNF* treatment.Kamleh, Muhammad Anas; Snowden, Stuart G; Grapov, Dmitry; Blackburn, Gavin J; Watson, David G; Xu, Ning; Stahle, Mona; Wheelock, Craig EJournal of proteome research.2015 Jan 2;557-6625361234
Rapid-throughput glycomics applied to human milk oligosaccharide profiling for large human studies.Totten, Sarah M; Wu, Lauren D; Parker, Evan A; Davis, Jasmine C C; Hua, Serenus; Stroble, Carol; Ruhaak, L Renee; Smilowitz, Jennifer T; German, J Bruce; Lebrilla, Carlito BAnalytical and bioanalytical chemistry.2014 Dec;7925-3525358913
Urinary metabolite profiling combined with computational analysis predicts interstitial cystitis-associated candidate biomarkers.Wen, He; Lee, Tack; You, Sungyong; Park, Soo-Hwan; Song, Hosook; Eilber, Karyn S; Anger, Jennifer T; Freeman, Michael R; Park, Sunghyouk; Kim, JayoungJournal of proteome research.2015 Jan 2;541-825353990
LipidBlast templates as flexible tools for creating new in-silico tandem mass spectral libraries.Kind, Tobias; Okazaki, Yozo; Saito, Kazuki; Fiehn, OliverAnalytical chemistry.2014 Nov 18;11024-725340521
The human colostrum whey proteome is altered in gestational diabetes mellitus.Grapov, Dmitry; Lemay, Danielle G; Weber, Darren; Phinney, Brett S; Azulay Chertok, Ilana R; Gho, Deborah S; German, J Bruce; Smilowitz, Jennifer TJournal of proteome research.2015 Jan 2;512-2025338220
Unified and isomer-specific NMR metabolomics database for the accurate analysis of (13)C-(1)H HSQC spectra.Bingol, Kerem; Li, Da-Wei; Bruschweiler-Li, Lei; Cabrera, Oscar A; Megraw, Timothy; Zhang, Fengli; Bruschweiler, RafaelACS chemical biology.2015 Feb 20;452-925333826
Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry.Cajka, Tomas; Fiehn, OliverTrends in analytical chemistry : TRAC.2014 Oct 1;192-20625309011
Development of an analytical method for assessment of silver nanoparticle content in biological matrices by inductively coupled plasma mass spectrometry.Poitras, Eric P; Levine, Michael A; Harrington, James M; Essader, Amal S; Fennell, Timothy R; Snyder, Rodney W; Black, Sherry L; Sumner, Susan S; Levine, Keith EBiological trace element research.2015 Feb;184-9225308764
Cold adaptation shapes the robustness of metabolic networks in Drosophila melanogaster.Williams, Caroline M; Watanabe, Miki; Guarracino, Mario R; Ferraro, Maria B; Edison, Arthur S; Morgan, Theodore J; Boroujerdi, Arezue F B; Hahn, Daniel AEvolution; international journal of organic evolution.2014 Dec;3505-2325308124
Time lag of glucose from intravascular to interstitial compartment in type 1 diabetes.Basu, Ananda; Dube, Simmi; Veettil, Sona; Slama, Michael; Kudva, Yogish C; Peyser, Thomas; Carter, Rickey E; Cobelli, Claudio; Basu, RitaJournal of diabetes science and technology.2015 Jan;63-825305282
11*-hydroxysteroid dehydrogenase types 1 and 2 activity in subcutaneous adipose tissue in humans: implications in obesity and diabetes.Dube, Simmi; Norby, Barbara J; Pattan, Vishwanath; Carter, Rickey E; Basu, Ananda; Basu, RitaThe Journal of clinical endocrinology and metabolism.2015 Jan;E70-625303491
Bifidobacterium longum subspecies infantis: champion colonizer of the infant gut.Underwood, Mark A; German, J Bruce; Lebrilla, Carlito B; Mills, David APediatric research.2015 Jan;229-3525303277
The urinary metabolomics profile of an Italian autistic children population and their unaffected siblings.Noto, Antonio; Fanos, Vassilios; Barberini, Luigi; Grapov, Dmitry; Fattuoni, Claudia; Zaffanello, Marco; Casanova, Andrea; Fenu, Gianni; De Giacomo, Andrea; De Angelis, Maria; Moretti, Corrado; Papoff, Paola; Ditonno, Raffaella; Francavilla, RuggieroThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.2014 Oct;46-5225284177
Urinary metabolomics (GC-MS) reveals that low and high birth weight infants share elevated inositol concentrations at birth.Barberini, Luigi; Noto, Antonio; Fattuoni, Claudia; Grapov, Dmitry; Casanova, Andrea; Fenu, Gianni; Gaviano, Mauro; Carboni, Roberta; Ottonello, Giovanni; Crisafulli, Maurizio; Fanos, Vassilios; Dessi, AngelicaThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.2014 Oct;20-625284173
Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance.Moon, Young-Ah; Ochoa, Courtney R; Mitsche, Matthew A; Hammer, Robert E; Horton, Jay DJournal of lipid research.2014 Dec;2597-60525281760
Stable isotope-labeled tracers for metabolic pathway elucidation by GC-MS and FT-MS.Higashi, Richard M; Fan, Teresa W-M; Lorkiewicz, Pawel K; Moseley, Hunter N B; Lane, Andrew NMethods in molecular biology (Clifton, N.J.).2014;147-6725270929
The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase.Inloes, Jordon M; Hsu, Ku-Lung; Dix, Melissa M; Viader, Andreu; Masuda, Kim; Takei, Thais; Wood, Malcolm R; Cravatt, Benjamin FProceedings of the National Academy of Sciences of the United States of America.2014 Oct 14;14924-925267624
MS2Analyzer: A software for small molecule substructure annotations from accurate tandem mass spectra.Ma, Yan; Kind, Tobias; Yang, Dawei; Leon, Carlos; Fiehn, OliverAnalytical chemistry.2014 Nov 4;10724-3125263576
Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.Sporkova, Alexandra; Jichova, Sarka; Huskova, Zuzana; Kopkan, Libor; Nishiyama, Akira; Hwang, Sung H; Hammock, Bruce D; Imig, John D; Kompanowska-Jezierska, Elzbieta; Sadowski, Janusz; Kramer, Herbert J; Cervenka, LudekClinical and experimental pharmacology & physiology.2014 Dec;1003-1325224811
High insulin combined with essential amino acids stimulates skeletal muscle mitochondrial protein synthesis while decreasing insulin sensitivity in healthy humans.Robinson, Matthew M; Soop, Mattias; Sohn, Tae Seo; Morse, Dawn M; Schimke, Jill M; Klaus, Katherine A; Nair, K SreekumaranThe Journal of clinical endocrinology and metabolism.2014 Dec;E2574-8325222757
Disruption of heme-peptide covalent cross-linking in mammalian peroxidases by hypochlorous acid.Abu-Soud, Husam M; Maitra, Dhiman; Shaeib, Faten; Khan, Sana N; Byun, Jaeman; Abdulhamid, Ibrahim; Yang, Zhe; Saed, Ghassan M; Diamond, Michael P; Andreana, Peter R; Pennathur, SubramaniamJournal of inorganic biochemistry.2014 Nov;245-5425193127
Effects of increased free fatty acid availability on adipose tissue fatty acid storage in men.Mundi, Manpreet S; Koutsari, Chistina; Jensen, Michael DThe Journal of clinical endocrinology and metabolism.2014 Dec;E2635-4225192251
Crucial role of macrophage selenoproteins in experimental colitis.Kaushal, Naveen; Kudva, Avinash K; Patterson, Andrew D; Chiaro, Christopher; Kennett, Mary J; Desai, Dhimant; Amin, Shantu; Carlson, Bradley A; Cantorna, Margherita T; Prabhu, K SandeepJournal of immunology (Baltimore, Md. : 1950).2014 Oct 1;3683-9225187657
Comparative evaluation of extraction methods for simultaneous mass-spectrometric analysis of complex lipids and primary metabolites from human blood plasma.Lee, Do Yup; Kind, Tobias; Yoon, Young-Ran; Fiehn, Oliver; Liu, Kwang-HyeonAnalytical and bioanalytical chemistry.2014 Nov;7275-8625171832
Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma.Ono, Emiko; Dutile, Stefanie; Kazani, Shamsah; Wechsler, Michael E; Yang, Jun; Hammock, Bruce D; Douda, David Nobuhiro; Tabet, Yacine; Khaddaj-Mallat, Rayan; Sirois, Marco; Sirois, Chantal; Rizcallah, Edmond; Rousseau, Eric; Martin, Richard; Sutherland, E Rand; Castro, Mario; Jarjour, Nizar N; Israel, Elliot; Levy, Bruce D; National Heart, Lung, and Blood Institute's Asthma Clinical Research NetworkAmerican journal of respiratory and critical care medicine.2014 Oct 15;886-9725162465
Credentialing features: a platform to benchmark and optimize untargeted metabolomic methods.Mahieu, Nathaniel Guy; Huang, Xiaojing; Chen, Ying-Jr; Patti, Gary JAnalytical chemistry.2014 Oct 7;9583-925160088
Microbial Determinants of Biochemical Individuality and Their Impact on Toxicology and Pharmacology.Patterson, Andrew D; Turnbaugh, Peter JCell metabolism2014 Aug 20NULL25156450
Glutamate enrichment as new diagnostic opportunity in breast cancer.Budczies, Jan; Pfitzner, Berit M; Gyorffy, Balazs; Winzer, Klaus-Jurgen; Radke, Cornelia; Dietel, Manfred; Fiehn, Oliver; Denkert, CarstenInternational journal of cancer. Journal international du cancer.2015 Apr 1;1619-2825155347
Inflammation triggers production of dimethylsphingosine from oligodendrocytes.Chen, Y-J; Hill, S; Huang, H; Taraboletti, A; Cho, K; Gallo, R; Manchester, M; Shriver, L P; Patti, G JNeuroscience.2014 Oct 24;113-2125151189
Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model.Despa, Sanda; Sharma, Savita; Harris, Todd R; Dong, Hua; Li, Ning; Chiamvimonvat, Nipavan; Taegtmeyer, Heinrich; Margulies, Kenneth B; Hammock, Bruce D; Despa, FlorinJournal of the American Heart Association2014 AugNULL25146704
Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.Hu, Biao; Liu, Jianhua; Wu, Zhe; Liu, Tianju; Ullenbruch, Matthew R; Ding, Lin; Henke, Craig A; Bitterman, Peter B; Phan, Sem HAmerican journal of respiratory cell and molecular biology.2015 Apr;418-2825140582
¹³C NMR metabolomics: applications at natural abundance.Clendinen, Chaevien S; Lee-McMullen, Brittany; Williams, Caroline M; Stupp, Gregory S; Vandenborne, Krista; Hahn, Daniel A; Walter, Glenn A; Edison, Arthur SAnalytical chemistry.2014 Sep 16;9242-5025140385
Development and in silico evaluation of large-scale metabolite identification methods using functional group detection for metabolomics.Mitchell, Joshua M; Fan, Teresa W-M; Lane, Andrew N; Moseley, Hunter N BFrontiers in genetics.2014;23725120557
Catecholamine-resistant hypotension and myocardial performance following patent ductus arteriosus ligation.Noori, S; McNamara, P; Jain, A; Lavoie, P M; Wickremasinghe, A; Merritt, T A; Solomon, T; Sekar, K; Attridge, J T; Swanson, J R; Gillam-Krakauer, M; Reese, J; Poindexter, B B; Brook, M; Auchus, R J; Clyman, R I; PDA Ligation/Hypotension Trial InvestigatorsJournal of perinatology : official journal of the California Perinatal Association.2015 Feb;123-725118721
Structural analysis of N- and O-glycans using ZIC-HILIC/dialysis coupled to NMR detection.Qu, Yi; Feng, Ju; Deng, Shuang; Cao, Li; Zhang, Qibin; Zhao, Rui; Zhang, Zhaorui; Jiang, Yuxuan; Zink, Erika M; Baker, Scott E; Lipton, Mary S; Pasa-Tolic, Ljiljana; Hu, Jian Zhi; Wu, SiFungal genetics and biology : FG & B.2014 Nov;207-1525117693
Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.Hayashi, Genki; Shen, Yan; Pedersen, Theresa L; Newman, John W; Pook, Mark; Cortopassi, GinoHuman molecular genetics.2014 Dec 20;6838-4725104852
Increasing Confidence of LC-MS Identifications by Utilizing Ion Mobility Spectrometry.Crowell, Kevin L; Baker, Erin S; Payne, Samuel H; Ibrahim, Yehia M; Monroe, Matthew E; Slysz, Gordon W; LaMarche, Brian L; Petyuk, Vladislav A; Piehowski, Paul D; Danielson 3rd, William F; Anderson, Gordon A; Smith, Richard DInternational journal of mass spectrometry.2013 Nov 15;312-31725089116
PVP formulated fullerene (C60) increases Rho-kinase dependent vascular tissue contractility in pregnant Sprague Dawley rats.Vidanapathirana, Achini K; Thompson, Leslie C; Mann, Erin E; Odom, Jillian T; Holland, Nathan A; Sumner, Susan J; Han, Li; Lewin, Anita H; Fennell, Timothy R; Brown, Jared M; Wingard, Christopher JReproductive toxicology (Elmsford, N.Y.).2014 Nov;86-10025088243
Perinatal exposure of mice to the pesticide DDT impairs energy expenditure and metabolism in adult female offspring.La Merrill, Michele; Karey, Emma; Moshier, Erin; Lindtner, Claudia; La Frano, Michael R; Newman, John W; Buettner, ChristophPloS one.2014;e10333725076055
Proteasome function is required for platelet production.Shi, Dallas S; Smith, Matthew C P; Campbell, Robert A; Zimmerman, Patrick W; Franks, Zechariah B; Kraemer, Bjorn F; Machlus, Kellie R; Ling, Jing; Kamba, Patrick; Schwertz, Hansjorg; Rowley, Jesse W; Miles, Rodney R; Liu, Zhi-Jian; Sola-Visner, Martha; Italiano Jr, Joseph E; Christensen, Hilary; Kahr, Walter H A; Li, Dean Y; Weyrich, Andrew SThe Journal of clinical investigation.2014 Sep;3757-6625061876
Thermally-Induced Substrate Release Via Intramolecular Cyclizations of Amino Esters and Amino Carbonates.Knipp, Ralph J; Estrada, Rosendo; Sethu, Palaniappan; Nantz, Michael HTetrahedron2014 May 13422-342925061237
Tracing flavonoid degradation in grapes by MS filtering with stable isotopes.Chassy, Alexander W; Bueschl, Christoph; Lee, Hyeyoung; Lerno, Larry; Oberholster, Anita; Barile, Daniela; Schuhmacher, Rainer; Waterhouse, Andrew LFood chemistry2015 Jan 1448-5525053079
The effect of vagal nerve blockade using electrical impulses on glucose metabolism in nondiabetic subjects.Sathananthan, Matheni; Ikramuddin, Sayeed; Swain, James M; Shah, Meera; Piccinini, Francesca; Dalla Man, Chiara; Cobelli, Claudio; Rizza, Robert A; Camilleri, Michael; Vella, AdrianDiabetes, metabolic syndrome and obesity : targets and therapy.2014;305-1225050073
Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signaling.Vendelbo, Mikkel Holm; Moller, Andreas Buch; Christensen, Britt; Nellemann, Birgitte; Clasen, Berthil Frederik Forrest; Nair, K Sreekumaran; Jorgensen, Jens Otto Lunde; Jessen, Niels; Moller, NielsPloS one.2014;e10203125020061
Salvage of the thiamin pyrimidine moiety by plant TenA proteins lacking an active-site cysteine.Zallot, Remi; Yazdani, Mohammad; Goyer, Aymeric; Ziemak, Michael J; Guan, Jiahn-Chou; McCarty, Donald R; de Crecy-Lagard, Valerie; Gerdes, Svetlana; Garrett, Timothy J; Benach, Jordi; Hunt, John F; Shintani, David K; Hanson, Andrew DThe Biochemical journal.2014 Oct 1;145-5525014715
Differential incorporation of glucose into biomass during Warburg metabolism.Chen, Ying-Jr; Huang, Xiaojing; Mahieu, Nathaniel G; Cho, Kevin; Schaefer, Jacob; Patti, Gary JBiochemistry.2014 Jul 29;4755-725010499
Enhanced detection and identification in metabolomics by use of LC-MS/MS untargeted analysis in combination with gas-phase fractionation.Calder�n-Santiago, M�nica; Priego-Capote, Feliciano; Luque de Castro, Mar�a DAnalytical chemistry2014 Aug 524992377
Citrulline stimulates muscle protein synthesis in the post-absorptive state in healthy people fed a low-protein diet - A pilot study.Jourdan, Marion; Nair, K Sreekumaran; Carter, Rickey E; Schimke, Jill; Ford, G Charles; Marc, Julie; Aussel, Christian; Cynober, LucClinical nutrition (Edinburgh, Scotland).2015 Jun;449-5624972455
Studies of Secondary Melanoma on C57BL/6J Mouse Liver Using 1H NMR Metabolomics.Feng, Ju; Isern, Nancy G; Burton, Sarah D; Hu, Jian ZhiMetabolites.2013;1011-3524958263
Tryptophan catabolism restricts IFN-ýý-expressing neutrophils and Clostridium difficile immunopathology.El-Zaatari, Mohamad; Chang, Yu-Ming; Zhang, Min; Franz, Matthew; Shreiner, Andrew; McDermott, Andrew J; van der Sluijs, Koenraad F; Lutter, Rene; Grasberger, Helmut; Kamada, Nobuhiko; Young, Vincent B; Huffnagle, Gary B; Kao, John YJournal of immunology (Baltimore, Md. : 1950)2014 Jul 15807-1624935925
Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses.Gowda, Harsha; Ivanisevic, Julijana; Johnson, Caroline H; Kurczy, Michael E; Benton, H Paul; Rinehart, Duane; Nguyen, Thomas; Ray, Jayashree; Kuehl, Jennifer; Arevalo, Bernardo; Westenskow, Peter D; Wang, Junhua; Arkin, Adam P; Deutschbauer, Adam M; Patti, Gary J; Siuzdak, GaryAnalytical chemistry.2014 Jul 15;6931-924934772
Soluble epoxide hydrolase inhibitor attenuates inflammation and airway hyperresponsiveness in mice.Yang, Jun; Bratt, Jennifer; Franzi, Lisa; Liu, Jun-Yan; Zhang, Guodong; Zeki, Amir A; Vogel, Christoph F A; Williams, Keisha; Dong, Hua; Lin, Yanping; Hwang, Sung Hee; Kenyon, Nicholas J; Hammock, Bruce DAmerican journal of respiratory cell and molecular biology.2015 Jan;46-5524922186
Analysis of Human Serum and Whole Blood for Mineral Content by ICP-MS and ICP-OES: Development of a Mineralomics Method.Harrington, James M; Young, Daniel J; Essader, Amal S; Sumner, Susan J; Levine, Keith EBiological trace element research2014 Jun 11NULL24917052
Metabolomic data streaming for biology-dependent data acquisition.Rinehart, Duane; Johnson, Caroline H; Nguyen, Thomas; Ivanisevic, Julijana; Benton, H Paul; Lloyd, Jessica; Arkin, Adam P; Deutschbauer, Adam M; Patti, Gary J; Siuzdak, GaryNature biotechnology2014 Jun524-724911492
A tour through the transcriptional landscape of platelets.Schubert, Sebastian; Weyrich, Andrew S; Rowley, Jesse WBlood2014 Jul 24493-50224904119
Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins.Schebb, Nils Helge; Ostermann, Annika I; Yang, Jun; Hammock, Bruce D; Hahn, Andreas; Schuchardt, Jan PhilippProstaglandins & other lipid mediators2014 May 29NULL24880049
Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry.Gori, Sadakatali S; Lorkiewicz, Pawel; Ehringer, Daniel S; Belshoff, Alex C; Higashi, Richard M; Fan, Teresa W-M; Nantz, Michael HAnalytical and bioanalytical chemistry2014 Jul4371-924858467
Microbiota, oral microbiome, and pancreatic cancer.Michaud, Dominique S; Izard, JacquesCancer journal (Sudbury, Mass.)2014 May-Jun203-624855008
A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.Church, Rachel J; Wu, Hong; Mosedale, Merrie; Sumner, Susan J; Pathmasiri, Wimal; Kurtz, Catherine L; Pletcher, Mathew T; Eaddy, John S; Pandher, Karamjeet; Singer, Monica; Batheja, Ameesha; Watkins, Paul B; Adkins, Karissa; Harrill, Alison HToxicological sciences : an official journal of the Society of Toxicology2014 Aug 1481-9224848797
Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase.Charles, Rebecca L; Rudyk, Olena; Prysyazhna, Oleksandra; Kamynina, Alisa; Yang, Jun; Morisseau, Christophe; Hammock, Bruce D; Freeman, Bruce A; Eaton, PhilipProceedings of the National Academy of Sciences of the United States of America2014 Jun 38167-7224843165
Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation.Avanesov, Andrei S; Ma, Siming; Pierce, Kerry A; Yim, Sun Hee; Lee, Byung Cheon; Clish, Clary B; Gladyshev, Vadim NeLife2014e0207724843015
Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: An additional proatherogenic mechanism in systemic lupus erythematosus.Smith, Carolyne K; Vivekanandan-Giri, Anuradha; Tang, Chongren; Knight, Jason S; Mathew, Anna; Padilla, Robin L; Gillespie, Brenda W; Carmona-Rivera, Carmelo; Liu, Xiaodan; Subramanian, Venkataraman; Hasni, Sarfaraz; Thompson, Paul R; Heinecke, Jay W; SarArthritis & rheumatology (Hoboken, N.J.)2014 May 16NULL24838349
After the feature presentation: technologies bridging untargeted metabolomics and biology.Cho, Kevin; Mahieu, Nathaniel G; Johnson, Stephen L; Patti, Gary JCurrent opinion in biotechnology2014 May 5143-14824816495
Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group.Deutz, Nicolaas E P; Bauer, Jurgen M; Barazzoni, Rocco; Biolo, Gianni; Boirie, Yves; Bosy-Westphal, Anja; Cederholm, Tommy; Cruz-Jentoft, Alfonso; Krznaric, Zeljko; Nair, K Sreekumaran; Singer, Pierre; Teta, Daniel; Tipton, Kevin; Calder, Philip CClinical nutrition (Edinburgh, Scotland).2014 Dec;929-3624814383
Quantitative NMR Metabolite Profiling of Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Discriminates between Biofilm and Planktonic Phenotypes.Ammons, Mary Cloud B; Tripet, Brian P; Carlson, Ross P; Kirker, Kelly R; Gross, Michael A; Stanisich, Jessica J; Copie, ValerieJournal of proteome research2014 Jun 62973-8524809402
Gastrointestinal microbes interact with canine adipose-derived mesenchymal stem cells in vitro and enhance immunomodulatory functions.Kol, Amir; Foutouhi, Soraya; Walker, Naomi J; Kong, Nguyet T; Weimer, Bart C; Borjesson, Dori LStem cells and development.2014 Aug 15;1831-4324803072
Detecting and Removing Data Artifacts in Hadamard Transform Ion Mobility-Mass Spectrometry Measurements.Prost, Spencer A; Crowell, Kevin L; Baker, Erin S; Ibrahim, Yehia M; Clowers, Brian H; Monroe, Matthew E; Anderson, Gordon A; Smith, Richard D; Payne, Samuel HJournal of the American Society for Mass Spectrometry2014 May 6NULL24796262
Improving Ion Mobility Measurement Sensitivity by Utilizing Helium in an Ion Funnel Trap.Ibrahim, Yehia M; Garimella, Sandilya V B; Tolmachev, Aleksey V; Baker, Erin S; Smith, Richard DAnalytical chemistry2014 May 13NULL24786390
Customized Metabolomics Database for the Analysis of NMR (1)H-(1)H TOCSY and (13)C-(1)H HSQC-TOCSY Spectra of Complex Mixtures.Bingol, Kerem; Bruschweiler-Li, Lei; Li, Da-Wei; Bruschweiler, RafaelAnalytical chemistry2014 May 20NULL24773139
A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels.Lanning, Nathan J; Looyenga, Brendan D; Kauffman, Audra L; Niemi, Natalie M; Sudderth, Jessica; DeBerardinis, Ralph J; MacKeigan, Jeffrey PCell reports2014 May 8907-1724767988
mTORC1-independent reduction of retinal protein synthesis in type 1 diabetes.Fort, Patrice E; Losiewicz, Mandy K; Pennathur, Subramaniam; Jefferson, Leonard S; Kimball, Scot R; Abcouwer, Steven F; Gardner, Thomas WDiabetes.2014 Sep;3077-9024740573
Noninvasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer.Mathe, Ewy A; Patterson, Andrew D; Haznadar, Majda; Manna, Soumen K; Krausz, Kristopher W; Bowman, Elise D; Shields, Peter G; Idle, Jeffrey R; Smith, Philip B; Anami, Katsuhiro; Kazandjian, Dickran G; Hatzakis, Emmanuel; Gonzalez, Frank J; Harris, Curtis Cancer research2014 Jun 153259-7024736543
Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.Xie, Han; Hanai, Jun-Ichi; Ren, Jian-Guo; Kats, Lev; Burgess, Kerri; Bhargava, Parul; Signoretti, Sabina; Billiard, Julia; Duffy, Kevin J; Grant, Aaron; Wang, Xiaoen; Lorkiewicz, Pawel K; Schatzman, Sabrina; Bousamra 2nd, Michael; Lane, Andrew N; Higashi,Cell metabolism2014 May 6795-80924726384
Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis.Nishizawa, Tomohiro; Kanter, Jenny E; Kramer, Farah; Barnhart, Shelley; Shen, Xia; Vivekanandan-Giri, Anuradha; Wall, Valerie Z; Kowitz, Jason; Devaraj, Sridevi; O'Brien, Kevin D; Pennathur, Subramaniam; Tang, Jingjing; Miyaoka, Robert S; Raines, Elaine WCell reports2014 Apr 24356-6524726364
MR microscopy of formalin fixed paraffin embedded histology specimens.Macura, Slobodan; Mishra, Prasanna K; Gamez, Jeffrey D; Pirko, IstvanMagnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine2014 Jun1989-9424715442
MetDisease--connecting metabolites to diseases via literature.Duren, William; Weymouth, Terry; Hull, Tim; Omenn, Gilbert S; Athey, Brian; Burant, Charles; Karnovsky, AllaBioinformatics (Oxford, England)2014 Apr 23NULL24713438
LC-MS-based metabolomics: an update.Fang, Zhong-Ze; Gonzalez, Frank JArchives of toxicology.2014 Aug;1491-50224710571
Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.Guin, Sunny; Pollard, Courtney; Ru, Yuanbin; Ritterson Lew, Carolyn; Duex, Jason E; Dancik, Garrett; Owens, Charles; Spencer, Andrea; Knight, Scott; Holemon, Heather; Gupta, Sounak; Hansel, Donna; Hellerstein, Marc; Lorkiewicz, Pawel; Lane, Andrew N; Fan,Journal of the National Cancer Institute2014 MayNULL24700805
An Omega-3 Epoxide of Docosahexaenoic Acid Lowers Blood Pressure in Angiotensin-II Dependent Hypertension.Ulu, Arzu; Stephen Lee, Kin Sing; Miyabe, Christina; Yang, Jun; Hammock, Bruce G; Dong, Hua; Hammock, Bruce DJournal of cardiovascular pharmacology2014 Mar 31NULL24691274
Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets.O'Donnell, Valerie B; Murphy, Robert C; Watson, Steve PCirculation research2014 Mar 281185-20324677238
Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretion.El-Azzouny, Mahmoud; Evans, Charles R; Treutelaar, Mary K; Kennedy, Robert T; Burant, Charles FThe Journal of biological chemistry2014 May 913575-8824675078
Continuous 24-Hour Leptin, Proopiomelanocortin and Amino Acid Measurements in Human Cerebrospinal Fluid: Correlations with Plasma Leptin, Soluble Leptin Receptor and Amino Acid Levels.Wardlaw, Sharon L; Burant, Charles F; Klein, Samuel; Meece, Kana; White, Anne; Kasten, Tom; Lucey, Brendan P; Bateman, Randall JThe Journal of clinical endocrinology and metabolism2014 Mar 26jc2013408724670082
Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA.Schuchardt, Jan Philipp; Schneider, Inga; Willenberg, Ina; Yang, Jun; Hammock, Bruce D; Hahn, Andreas; Schebb, Nils HelgeProstaglandins & other lipid mediators2014 Jun23-3124667634
Modular organization of cardiac energy metabolism: energy conversion, transfer and feedback regulation.Guzun, R; Kaambre, T; Bagur, R; Grichine, A; Usson, Y; Varikmaa, M; Anmann, T; Tepp, K; Timohhina, N; Shevchuk, I; Chekulayev, V; Boucher, F; Dos Santos, P; Schlattner, U; Wallimann, T; Kuznetsov, A V; Dzeja, P; Aliev, M; Saks, VActa physiologica (Oxford, England)2014 Mar 26NULL24666671
Leucine modulates dynamic phosphorylation events in insulin signaling pathway and enhances insulin-dependent glycogen synthesis in human skeletal muscle cells.Di Camillo, Barbara; Eduati, Federica; Nair, Sreekumaran K; Avogaro, Angelo; Toffolo, Gianna MBMC cell biology.2014;924646332
Hypotension following patent ductus arteriosus ligation: the role of adrenal hormones.Clyman, Ronald I; Wickremasinghe, Andrea; Merritt, T Allen; Solomon, Tabitha; McNamara, Patrick; Jain, Amish; Singh, Jaideep; Chu, Alison; Noori, Shahab; Sekar, Krishnamurthy; Lavoie, Pascal M; Attridge, Joshua T; Swanson, Jonathan R; Gillam-Krakauer, MarThe Journal of pediatrics2014 Jun1449-55.e124636853
Accumulation of high-value lipids in single-cell microorganisms: a mechanistic approach and future perspectives.Garay, Luis A; Boundy-Mills, Kyria L; German, J BruceJournal of agricultural and food chemistry2014 Apr 22709-2724628496
Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome.Roberts, Lee D; Koulman, Albert; Griffin, Julian LThe lancet. Diabetes & endocrinology2014 Jan65-7524622670
Tracing phenolic metabolism in Vitis vinifera berries with 13C6-phenylalanine: implication of an unidentified intermediate reservoir.Chassy, Alexander W; Adams, Douglas O; Waterhouse, Andrew LJournal of agricultural and food chemistry2014 Mar 192321-624611798
Alteration of the murine gastrointestinal microbiota by tigecycline leads to increased susceptibility to Clostridium difficile infection.Bassis, Christine M; Theriot, Casey M; Young, Vincent BAntimicrobial agents and chemotherapy2014 May2767-7424590475
Relationship of muscle sympathetic nerve activity to insulin sensitivity.Curry, Timothy B; Hines, Casey N; Barnes, Jill N; Somaraju, Madhuri; Basu, Rita; Miles, John M; Joyner, Michael J; Charkoudian, NishaClinical autonomic research : official journal of the Clinical Autonomic Research Society.2014 Apr;77-8524577625
Impact of a transposon insertion in phzF2 on the specialized metabolite production and interkingdom interactions of Pseudomonas aeruginosa.Phelan, Vanessa V; Moree, Wilna J; Aguilar, Julieta; Cornett, Dale S; Koumoutsi, Alexandra; Noble, Suzanne M; Pogliano, Kit; Guerrero, Carlos A; Dorrestein, Pieter CJournal of bacteriology2014 May1683-9324532776
A multimodal intervention for patients with secondary progressive multiple sclerosis: feasibility and effect on fatigue.Bisht, Babita; Darling, Warren G; Grossmann, Ruth E; Shivapour, E Torage; Lutgendorf, Susan K; Snetselaar, Linda G; Hall, Michael J; Zimmerman, M Bridget; Wahls, Terry LJournal of alternative and complementary medicine (New York, N.Y.).2014 May;347-5524476345
Administration of saccharin to neonatal mice influences body composition of adult males and reduces body weight of females.Parlee, Sebastian D; Simon, Becky R; Scheller, Erica L; Alejandro, Emilyn U; Learman, Brian S; Krishnan, Venkatesh; Bernal-Mizrachi, Ernesto; MacDougald, Ormond AEndocrinology2014 Apr1313-2624456165
Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection.Theriot, Casey M; Koenigsknecht, Mark J; Carlson Jr, Paul E; Hatton, Gabrielle E; Nelson, Adam M; Li, Bo; Huffnagle, Gary B; Z Li, Jun; Young, Vincent BNature communications2014311424445449
Cýýýýýý exposure augments cardiac ischemia/reperfusion injury and coronary artery contraction in Sprague Dawley rats.Thompson, Leslie C; Urankar, Rakhee N; Holland, Nathan A; Vidanapathirana, Achini K; Pitzer, Joshua E; Han, Li; Sumner, Susan J; Lewin, Anita H; Fennell, Timothy R; Lust, Robert M; Brown, Jared M; Wingard, Christopher JToxicological sciences : an official journal of the Society of Toxicology.2014 Apr;365-7824431213
Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.Niewczas, Monika A; Sirich, Tammy L; Mathew, Anna V; Skupien, Jan; Mohney, Robert P; Warram, James H; Smiles, Adam; Huang, Xiaoping; Walker, Walker; Byun, Jaeman; Karoly, Edward D; Kensicki, Elizabeth M; Berry, Gerard T; Bonventre, Joseph V; Pennathur, SuKidney international2014 Jan 15NULL24429397
Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin.Campbell, Caitlin; Grapov, Dmitry; Fiehn, Oliver; Chandler, Carol J; Burnett, Dustin J; Souza, Elaine C; Casazza, Gretchen A; Gustafson, Mary B; Keim, Nancy L; Newman, John W; Hunter, Gary R; Fernandez, Jose R; Garvey, W Timothy; Harper, Mary-Ellen; HoppePloS one2014e8426024416208
Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men.Schuchardt, Jan Philipp; Schmidt, Simone; Kressel, Gaby; Willenberg, Ina; Hammock, Bruce D; Hahn, Andreas; Schebb, Nils HelgeProstaglandins, leukotrienes, and essential fatty acids2014 Feb-Mar27-3724411718
A Computational Framework for High-Throughput Isotopic Natural Abundance Correction of Omics-Level Ultra-High Resolution FT-MS Datasets.Carreer, William J; Flight, Robert M; Moseley, Hunter N BMetabolites2013 Sep 25NULL24404440
Advancing the high throughput identification of liver fibrosis protein signatures using multiplexed ion mobility spectrometry.Baker, Erin Shammel; Burnum-Johnson, Kristin E; Jacobs, Jon M; Diamond, Deborah L; Brown, Roslyn N; Ibrahim, Yehia M; Orton, Daniel J; Piehowski, Paul D; Purdy, David E; Moore, Ronald J; Danielson 3rd, William F; Monroe, Matthew E; Crowell, Kevin L; SlyszMolecular & cellular proteomics : MCP2014 Apr1119-2724403597
Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease.Shu, Liming; Vivekanandan-Giri, Anuradha; Pennathur, Subramaniam; Smid, Bouwien E; Aerts, Johannes M F G; Hollak, Carla E M; Shayman, James AKidney international.2014 Jul;58-6624402087
X13CMS: global tracking of isotopic labels in untargeted metabolomics.Huang, Xiaojing; Chen, Ying-Jr; Cho, Kevin; Nikolskiy, Igor; Crawford, Peter A; Patti, Gary JAnalytical chemistry2014 Feb 41632-924397582
Key role of microRNA in the regulation of granulocyte macrophage colony-stimulating factor expression in murine alveolar epithelial cells during oxidative stress.Sturrock, Anne; Mir-Kasimov, Mustafa; Baker, Jessica; Rowley, Jesse; Paine 3rd, RobertThe Journal of biological chemistry2014 Feb 144095-10524371146
Microbial and metabolic interactions between the gastrointestinal tract and Clostridium difficile infection.Theriot, Casey M; Young, Vincent BGut microbes.2014 Jan-Feb;86-9524335555
Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice.Zhang, Wanying; Li, Haonan; Dong, Hua; Liao, Jie; Hammock, Bruce D; Yang, Guang-YuAnticancer research2013 Dec5261-7124324059
Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health.Evans, Charles R; Karnovsky, Alla; Kovach, Melissa A; Standiford, Theodore J; Burant, Charles F; Stringer, Kathleen AJournal of proteome research2014 Feb 7640-924289193
Monitoring metabolic responses to chemotherapy in single cells and tumors using nanostructure-initiator mass spectrometry (NIMS) imaging.O'Brien, Peter J; Lee, Michelle; Spilker, Mary E; Zhang, Cathy C; Yan, Zhengming; Nichols, Timothy C; Li, Wenlin; Johnson, Caroline H; Patti, Gary J; Siuzdak, GaryCancer & metabolism2013424280026
Isotopic Ratio Outlier Analysis Global Metabolomics of Caenorhabditis elegans.Stupp, Gregory S; Clendinen, Chaevien S; Ajredini, Ramadan; Szewc, Mark A; Garrett, Timothy; Menger, Robert F; Yost, Richard A; Beecher, Chris; Edison, Arthur SAnalytical chemistry2013 Dec 1711858-6524274725
Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung.Yang, Jun; Solaimani, Parrisa; Dong, Hua; Hammock, Bruce; Hankinson, OliverThe Journal of toxicological sciences2013833-624213002
Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids.Nording, Malin L; Yang, Jun; Georgi, Katrin; Hegedus Karbowski, Christine; German, J Bruce; Weiss, Robert H; Hogg, Ronald J; Trygg, Johan; Hammock, Bruce D; Zivkovic, Angela MPloS one2013e7657524204640
A Metabolomics Investigation of Non-genotoxic Carcinogenicity in the Rat.Ament, Zsuzsanna; Waterman, Claire L; West, James A; Waterfield, Catherine; Currie, Richard A; Wright, Jayne; Griffin, Julian LJournal of proteome research2013 Dec 65775-9024161236
Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice.Schuster, Gertrud U; Bratt, Jennifer M; Jiang, Xiaowen; Pedersen, Theresa L; Grapov, Dmitry; Adkins, Yuriko; Kelley, Darshan S; Newman, John W; Kenyon, Nicholas J; Stephensen, Charles BAmerican journal of respiratory cell and molecular biology2014 Mar626-3624134486
Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis.Gardell, Alison M; Yang, Jun; Sacchi, Romina; Fangue, Nann A; Hammock, Bruce D; Kultz, DietmarThe Journal of experimental biology2013 Dec 154615-2524072790
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice.Frolov, Andrey; Yang, Lihua; Dong, Hua; Hammock, Bruce D; Crofford, Leslie JProstaglandins, leukotrienes, and essential fatty acids2013 Oct351-824055573
Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications.Ghanta, Sirisha; Grossmann, Ruth E; Brenner, CharlesCritical reviews in biochemistry and molecular biology2013 Nov-Dec561-7424050258
Human milk secretory immunoglobulin a and lactoferrin N-glycans are altered in women with gestational diabetes mellitus.Smilowitz, Jennifer T; Totten, Sarah M; Huang, Jincui; Grapov, Dmitry; Durham, Holiday A; Lammi-Keefe, Carol J; Lebrilla, Carlito; German, J BruceThe Journal of nutrition2013 Dec1906-1224047700
LC-IMS-MS Feature Finder: detecting multidimensional liquid chromatography, ion mobility and mass spectrometry features in complex datasets.Crowell, Kevin L; Slysz, Gordon W; Baker, Erin S; LaMarche, Brian L; Monroe, Matthew E; Ibrahim, Yehia M; Payne, Samuel H; Anderson, Gordon A; Smith, Richard DBioinformatics (Oxford, England)2013 Nov 12804-524008421
Long-Chain Acyl Coenzyme A Synthetase 1 Overexpression in Primary Cultured Schwann Cells Prevents Long Chain Fatty Acid-Induced Oxidative Stress and Mitochondrial Dysfunction.Hinder, Lucy M; Figueroa-Romero, Claudia; Pacut, Crystal; Hong, Yu; Vivekanandan-Giri, Anuradha; Pennathur, Subramaniam; Feldman, Eva LAntioxidants & redox signaling2013 Oct 5NULL23991914
Preparation of 20-HETE using multifunctional enzyme type 2-negative Starmerella bombicola.Van Bogaert, Inge; Zhang, Guodong; Yang, Jun; Liu, Jun-Yan; Ye, Yonghao; Soetaert, Wim; Hammock, Bruce DJournal of lipid research2013 Nov3215-923966667
Mechanism of formation of the major estradiol product ions following collisional activation of the molecular anion in a tandem quadrupole mass spectrometer.Wooding, Kerry M; Barkley, Robert M; Hankin, Joseph A; Johnson, Christopher A; Bradford, Andrew P; Santoro, Nanette; Murphy, Robert CJournal of the American Society for Mass Spectrometry2013 Oct1451-523955001
Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects.Perroud, Bertrand; Jafar-Nejad, Paymaan; Wikoff, William R; Gatchel, Jennifer R; Wang, Lu; Barupal, Dinesh K; Crespo-Barreto, Juan; Fiehn, Oliver; Zoghbi, Huda Y; Kaddurah-Daouk, RimaPloS one2013e7061023936457
Cortisol response to operative stress with anesthesia in healthy children.Taylor, Lisa K; Auchus, Richard J; Baskin, Laurence S; Miller, Walter LThe Journal of clinical endocrinology and metabolism2013 Sep3687-9323861461
Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate.Davda, Dahvid; El Azzouny, Mahmoud A; Tom, Christopher T M B; Hernandez, Jeannie L; Majmudar, Jaimeen D; Kennedy, Robert T; Martin, Brent RACS chemical biology2013 Sep 201912-723844586
An untargeted metabolomic workflow to improve structural characterization of metabolites.Nikolskiy, Igor; Mahieu, Nathaniel G; Chen, Ying-Jr; Tautenhahn, Ralf; Patti, Gary JAnalytical chemistry2013 Aug 207713-923829391
Nutritional lipidomics: molecular metabolism, analytics, and diagnostics.Smilowitz, Jennifer T; Zivkovic, Angela M; Wan, Yu-Jui Yvonne; Watkins, Steve M; Nording, Malin L; Hammock, Bruce D; German, J BruceMolecular nutrition & food research2013 Aug1319-3523818328
LipidBlast in silico tandem mass spectrometry database for lipid identification.Kind, Tobias; Liu, Kwang-Hyeon; Lee, Do Yup; Defelice, Brian; Meissen, John K; Fiehn, OliverNature methods2013 Aug755-823817071
Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis.Frolov, Andrey; Dong, Hua; Jiang, Min; Yang, Lihua; Cook, Erik C; Matnani, Rahul; Hammock, Bruce D; Crofford, Leslie JThe Journal of biological chemistry2013 Aug 1623696-70323814065
Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.McDonnell, Scott R P; Hwang, Steven R; Rolland, Delphine; Murga-Zamalloa, Carlos; Basrur, Venkatesha; Conlon, Kevin P; Fermin, Damian; Wolfe, Thomas; Raskind, Alexander; Ruan, Chunhai; Jiang, Jian-Kang; Thomas, Craig J; Hogaboam, Cory M; Burant, Charles FBlood2013 Jun 27NULL23814019
Coordinate expression of transcripts and proteins in platelets.Rowley, Jesse W; Weyrich, Andrew SBlood2013 Jun 275255-623813941
MS/MS networking guided analysis of molecule and gene cluster families.Nguyen, Don Duy; Wu, Cheng-Hsuan; Moree, Wilna J; Lamsa, Anne; Medema, Marnix H; Zhao, Xiling; Gavilan, Ronnie G; Aparicio, Marystella; Atencio, Librada; Jackson, Chanaye; Ballesteros, Javier; Sanchez, Joel; Watrous, Jeramie D; Phelan, Vanessa V; van de WProceedings of the National Academy of Sciences of the United States of America2013 Jul 9E2611-2023798442
Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism.Ivanisevic, Julijana; Zhu, Zheng-Jiang; Plate, Lars; Tautenhahn, Ralf; Chen, Stephen; O'Brien, Peter J; Johnson, Caroline H; Marletta, Michael A; Patti, Gary J; Siuzdak, GaryAnalytical chemistry2013 Jul 166876-8423781873
HR-MAS NMR Tissue Metabolomic Signatures Cross-validated by Mass Spectrometry Distinguish Bladder Cancer from Benign Disease.Tripathi, Pratima; Somashekar, Bagganahalli S; Ponnusamy, M; Gursky, Amy; Dailey, Stephen; Kunju, Priya; Lee, Cheryl T; Chinnaiyan, Arul M; Rajendiran, Thekkelnaycke M; Ramamoorthy, AyyalusamyJournal of proteome research2013 Jul 53519-2823731241
Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men.Schuchardt, Jan Philipp; Schmidt, Simone; Kressel, Gaby; Dong, Hua; Willenberg, Ina; Hammock, Bruce D; Hahn, Andreas; Schebb, Nils HelgeProstaglandins, leukotrienes, and essential fatty acids2013 Jul19-2923694766
Anti-inflammatory Effects of Omega-3 Polyunsaturated Fatty Acids and Soluble Epoxide Hydrolase Inhibitors in Angiotensin-II Dependent Hypertension.Ulu, Arzu; Harris, Todd R; Morisseau, Christophe; Miyabe, Christina; Inoue, Hiromi; Schuster, Gertrud; Dong, Hua; Iosif, Ana-Maria; Liu, Jun-Yan; Weiss, Robert H; Chiamvimonvat, Nipavan; Imig, John D; Hammock, Bruce DJournal of cardiovascular pharmacology2013 May 14NULL23676336
Error Analysis and Propagation in Metabolomics Data Analysis.Moseley, Hunter N BComputational and structural biotechnology journal2013 Jan 123667718
Optimization of harvesting, extraction, and analytical protocols for UPLC-ESI-MS-based metabolomic analysis of adherent mammalian cancer cells.Bi, Huichang; Krausz, Kristopher W; Manna, Soumen K; Li, Fei; Johnson, Caroline H; Gonzalez, Frank JAnalytical and bioanalytical chemistry2013 Jun5279-8923604415
Mini-review: Lactoferrin: a bioinspired, anti-biofilm therapeutic.Ammons, M C; Copie, VBiofouling2013443-5523574002
Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.Dong, Chenfang; Yuan, Tingting; Wu, Yadi; Wang, Yifan; Fan, Teresa W M; Miriyala, Sumitra; Lin, Yiwei; Yao, Jun; Shi, Jian; Kang, Tiebang; Lorkiewicz, Pawel; St Clair, Daret; Hung, Mien-Chie; Evers, B Mark; Zhou, Binhua PCancer cell2013 Mar 18316-3123453623
Metabolome response to glucose in the ýý-cell line INS-1 832/13.Lorenz, Matthew A; El Azzouny, Mahmoud A; Kennedy, Robert T; Burant, Charles FThe Journal of biological chemistry2013 Apr 1210923-3523426361
The isotridecanyl side chain of plusbacin-A3 is essential for the transglycosylase inhibition of peptidoglycan biosynthesis.Kim, Sung Joon; Singh, Manmilan; Wohlrab, Aaron; Yu, Tsyr-Yan; Patti, Gary J; O'Connor, Robert D; VanNieuwenhze, Michael; Schaefer, JacobBiochemistry2013 Mar 1923421534
The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors.Dougherty, Joseph D; Maloney, Susan E; Wozniak, David F; Rieger, Michael A; Sonnenblick, Lisa; Coppola, Giovanni; Mahieu, Nathaniel G; Zhang, Juliet; Cai, Jinlu; Patti, Gary J; Abrahams, Brett S; Geschwind, Daniel H; Heintz, NathanielThe Journal of neuroscience : the official journal of the Society for Neuroscience.2013 Feb 13;2732-5323407934
ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice.Essien, Bryan E; Grasberger, Helmut; Romain, Rachael D; Law, David J; Veniaminova, Natalia A; Saqui-Salces, Milena; El-Zaatari, Mohamad; Tessier, Arthur; Hayes, Michael M; Yang, Alexander C; Merchant, Juanita LGastroenterology2013 Jun1466-77, 1477.e1-923395646
Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database.Zhu, Zheng-Jiang; Schultz, Andrew W; Wang, Junhua; Johnson, Caroline H; Yannone, Steven M; Patti, Gary J; Siuzdak, GaryNature protocols2013 Mar451-6023391889
Perinatal bisphenol A exposure promotes hyperactivity, lean body composition, and hormonal responses across the murine life course.Anderson, Olivia S; Peterson, Karen E; Sanchez, Brisa N; Zhang, Zhenzhen; Mancuso, Peter; Dolinoy, Dana CFASEB journal : official publication of the Federation of American Societies for Experimental Biology2013 Apr1784-9223345456
Mass spectrometry theory and application to adrenal diseases.Wooding, Kerry M; Auchus, Richard JMolecular and cellular endocrinology2013 May 22201-723333773
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.Vivekanandan-Giri, Anuradha; Slocum, Jessica L; Byun, Jaeman; Tang, Chongren; Sands, Robin L; Gillespie, Brenda W; Heinecke, Jay W; Saran, Rajiv; Kaplan, Mariana J; Pennathur, SubramaniamAnnals of the rheumatic diseases2013 Jan 12NULL23313808
Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology.Li, Fei; Pang, Xiaoyan; Krausz, Kristopher W; Jiang, Changtao; Chen, Chi; Cook, John A; Krishna, Murali C; Mitchell, James B; Gonzalez, Frank J; Patterson, Andrew DJournal of proteome research2013 Mar 11369-7623301521
Network motifs provide signatures that characterize metabolism.Shellman, Erin R; Burant, Charles F; Schnell, SantiagoMolecular bioSystems2013 Mar352-6023287894
Microbial metabolic exchange in 3D.Watrous, Jeramie D; Phelan, Vanessa V; Hsu, Cheng-Chih; Moree, Wilna J; Duggan, Brendan M; Alexandrov, Theodore; Dorrestein, Pieter CThe ISME journal2013 Apr770-8023283018
A view from above: cloud plots to visualize global metabolomic data.Patti, Gary J; Tautenhahn, Ralf; Rinehart, Duane; Cho, Kevin; Shriver, Leah P; Manchester, Marianne; Nikolskiy, Igor; Johnson, Caroline H; Mahieu, Nathaniel G; Siuzdak, GaryAnalytical chemistry.2013 Jan 15;798-80423206250
Metabolomics: an essential tool to understand the function of peroxisome proliferator-activated receptor alpha.Montanez, Jessica E; Peters, Jeffrey M; Correll, Jared B; Gonzalez, Frank J; Patterson, Andrew DToxicologic pathology2013 Feb410-823197196
A Carbonyl Capture Approach for Profiling Oxidized Metabolites in Cell Extracts.Mattingly, Stephanie J; Xu, Tao; Nantz, Michael H; Higashi, Richard M; Fan, Teresa W-MMetabolomics : Official journal of the Metabolomic Society.2012;989-99623175637
Pulmonary instillation of multi-walled carbon nanotubes promotes coronary vasoconstriction and exacerbates injury in isolated hearts.Thompson, Leslie C; Frasier, Chad R; Sloan, Ruben C; Mann, Erin E; Harrison, Benjamin S; Brown, Jared M; Brown, David A; Wingard, Christopher JNanotoxicology.2014 Feb;38-4923102262
Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes.Hinder, Lucy M; Vivekanandan-Giri, Anuradha; McLean, Lisa L; Pennathur, Subramaniam; Feldman, Eva LThe Journal of endocrinology2013 Jan4165023086140
Addressing the current bottlenecks of metabolomics: Isotopic Ratio Outlier Analysisýýý, an isotopic-labeling technique for accurate biochemical profiling.de Jong, Felice A; Beecher, ChrisBioanalysis.2012 Sep;2303-1423046270
An accelerated workflow for untargeted metabolomics using the METLIN database.Tautenhahn, Ralf; Cho, Kevin; Uritboonthai, Winnie; Zhu, Zhengjiang; Patti, Gary J; Siuzdak, GaryNature biotechnology.2012 Sep;826-822965049
Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 ýý.McInturff, Alison M; Cody, Mark J; Elliott, Elizabeth A; Glenn, Jared W; Rowley, Jesse W; Rondina, Matthew T; Yost, Christian CBlood2012 Oct 113118-2522919032
Association of plasma ýý-3 and ýý-6 lipids with burden of disease measures in bipolar subjects.Evans, Simon J; Kamali, Masoud; Prossin, Alan R; Harrington, Gloria J; Ellingrod, Vicki L; McInnis, Melvin G; Burant, Charles FJournal of psychiatric research.2012 Nov;1435-4122884424
Platelet mRNA: the meaning behind the message.Rowley, Jesse W; Schwertz, Hansjorg; Weyrich, Andrew SCurrent opinion in hematology2012 Sep385-9122814651
A short-term diet and exercise intervention ameliorates inflammation and markers of metabolic health in overweight/obese children.Izadpanah, Ali; Barnard, R James; Almeda, Anna Jane E; Baldwin, Gayle C; Bridges, Sydney A; Shellman, Erin R; Burant, Charles F; Roberts, Christian KAmerican journal of physiology. Endocrinology and metabolism.2012 Aug 15;E542-5022713506
XCMS Online: a web-based platform to process untargeted metabolomic data.Tautenhahn, Ralf; Patti, Gary J; Rinehart, Duane; Siuzdak, GaryAnalytical chemistry.2012 Jun 5;5035-922533540


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