Publications Search by Program
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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
NIH Director's Pioneer Award Program (2964)
| Publication Title | Authors | Journal | Publication Date | Page No | PubMedID |
|---|---|---|---|---|---|
| Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8. | Tillman, Matthew C; Khadka, Manoj; Duffy, Jonathon; Wang, Meng C; Ortlund, Eric A | Scientific reports. | 2019 Jul 10; | 31292465 | |
| Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. | Goodyer, William Rowland; Beyersdorf, Benjamin; Paik, David T; Tian, Lei; Li, Guang; Buikema, Jan W; Chirikian, Orlando; Choi, Shannon; Venkatraman, Sneha; Adams, Eliza L; Tessier-Lavigne, Marc; Wu, Joseph C; Wu, Sean M | Circulation research. | 2019 Jul 09; | 31284824 | |
| A comprehensive, multiscale framework for evaluation of arrhythmias arising from cell therapy in the whole post-myocardial infarcted heart. | Yu, Joseph K; Franceschi, William; Huang, Qinwen; Pashakhanloo, Farhad; Boyle, Patrick M; Trayanova, Natalia A | Scientific reports. | 2019 Jun 25; | 31239508 | |
| Mechanisms of Ca2+/calmodulin-dependent kinase II activation in single dendritic spines. | Chang, Jui-Yun; Nakahata, Yoshihisa; Hayano, Yuki; Yasuda, Ryohei | Nature communications. | 2019 Jun 25; | 31239443 | |
| Identifying and validating small molecules interacting with RNA (SMIRNAs). | Disney, Matthew D; Velagapudi, Sai Pradeep; Li, Yue; Costales, Matthew G; Childs-Disney, Jessica L | Methods in enzymology. | 2019; | 31239057 | |
| Cas9+ conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond. | Roberts, Allison W; Popov, Lauren M; Mitchell, Gabriel; Ching, Krystal L; Licht, Daniel J; Golovkine, Guillaume; Barton, Gregory M; Cox, Jeffery S | eLife. | 2019 Jun 17; | 31204998 | |
| Divergence in the functional organization of human and macaque auditory cortex revealed by fMRI responses to harmonic tones. | Norman-Haignere, Sam V; Kanwisher, Nancy; McDermott, Josh H; Conway, Bevil R | Nature neuroscience. | 2019 Jun 10; | 31182868 | |
| Sensitivity of Ablation Targets Prediction to Electrophysiological Parameter Variability in Image-Based Computational Models of Ventricular Tachycardia in Post-infarction Patients. | Deng, Dongdong; Prakosa, Adityo; Shade, Julie; Nikolov, Plamen; Trayanova, Natalia A | Frontiers in physiology. | 2019; | 31178758 | |
| RNA-guided DNA insertion with CRISPR-associated transposases. | Strecker, Jonathan; Ladha, Alim; Gardner, Zachary; Schmid-Burgk, Jonathan L; Makarova, Kira S; Koonin, Eugene V; Zhang, Feng | Science (New York, N.Y.). | 2019 Jun 06; | 31171706 | |
| The metabolites NADP+ and NADPH are the targets of the circadian protein Nocturnin (Curled). | Estrella, Michael A; Du, Jin; Chen, Li; Rath, Sneha; Prangley, Eliza; Chitrakar, Alisha; Aoki, Tsutomu; Schedl, Paul; Rabinowitz, Joshua; Korennykh, Alexei | Nature communications. | 2019 05 30; | 31147539 | |
| Mechanism of TRPM2 channel gating revealed by cryo-EM. | Xia, Shiyu; Wang, Longfei; Fu, Tian-Min; Wu, Hao | The FEBS journal. | 2019 May 30; | 31144442 | |
| Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage. | Meeske, Alexander J; Nakandakari-Higa, Sandra; Marraffini, Luciano A | Nature. | 2019 Jun; | 31142834 | |
| Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development. | Li, Guang; Tian, Lei; Goodyer, William; Kort, Eric J; Buikema, Jan W; Xu, Adele; Wu, Joseph C; Jovinge, Stefan; Wu, Sean M | Development (Cambridge, England). | 2019 Jun 14; | 31142541 | |
| Transient, Consequential Increases in Extracellular Potassium Ions Accompany Channelrhodopsin2 Excitation. | Octeau, J Christopher; Gangwani, Mohitkumar R; Allam, Sushmita L; Tran, Duy; Huang, Shuhan; Hoang-Trong, Tuan M; Golshani, Peyman; Rumbell, Timothy H; Kozloski, James R; Khakh, Baljit S | Cell reports. | 2019 May 21; | 31116972 | |
| Two-Color Volumetric Imaging of Neuronal Activity of Cortical Columns. | Han, Shuting; Yang, Weijian; Yuste, Rafael | Cell reports. | 2019 May 14; | 31091458 | |
| The ancestral and industrialized gut microbiota and implications for human health. | Sonnenburg, Erica D; Sonnenburg, Justin L | Nature reviews. Microbiology. | 2019 Jun; | 31089293 | |
| Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1. | Yousef, Hanadie; Czupalla, Cathrin J; Lee, Davis; Chen, Michelle B; Burke, Ashley N; Zera, Kristy A; Zandstra, Judith; Berber, Elisabeth; Lehallier, Benoit; Mathur, Vidhu; Nair, Ramesh V; Bonanno, Liana N; Yang, Andrew C; Peterson, Todd; Hadeiba, Husein; | Nature medicine. | 2019 06; | 31086348 | |
| Light-sheet microscopy in the near-infrared II window. | Wang, Feifei; Wan, Hao; Ma, Zhuoran; Zhong, Yeteng; Sun, Qinchao; Tian, Ye; Qu, Liangqiong; Du, Haotian; Zhang, Mingxi; Li, Lulin; Ma, Huilong; Luo, Jian; Liang, Yongye; Li, Wen Jung; Hong, Guosong; Liu, Lianqing; Dai, Hongjie | Nature methods. | 2019 Jun; | 31086342 | |
| Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. | Sanfilippo, Joseph E; Lorestani, Alexander; Koch, Matthias D; Bratton, Benjamin P; Siryaporn, Albert; Stone, Howard A; Gitai, Zemer | Nature microbiology. | 2019 May 13; | 31086313 | |
| Synthetic biology strategies for microbial biosynthesis of plant natural products. | Cravens, Aaron; Payne, James; Smolke, Christina D | Nature communications. | 2019 05 13; | 31086174 | |
| Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP. | Saneyoshi, Takeo; Matsuno, Hitomi; Suzuki, Akio; Murakoshi, Hideji; Hedrick, Nathan G; Agnello, Emily; O'Connell, Rory; Stratton, Margaret M; Yasuda, Ryohei; Hayashi, Yasunori | Neuron. | 2019 Jun 19; | 31078368 | |
| Representational similarity precedes category selectivity in the developing ventral visual pathway. | Cohen, Michael A; Dilks, Daniel D; Koldewyn, Kami; Weigelt, Sarah; Feather, Jenelle; Kell, Alexander Je; Keil, Boris; Fischl, Bruce; Zöllei, Lilla; Wald, Lawrence; Saxe, Rebecca; Kanwisher, Nancy | NeuroImage. | 2019 May 08; | 31077844 | |
| Advanced One- and Two-Dimensional Mesh Designs for Injectable Electronics. | Viveros, Robert D; Zhou, Tao; Hong, Guosong; Fu, Tian-Ming; Lin, Hao-Yu Greg; Lieber, Charles M | Nano letters. | 2019 06 12; | 31075202 | |
| NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. | Chen, Li; Zhang, Zhaoyue; Hoshino, Atsushi; Zheng, Henry D; Morley, Michael; Arany, Zoltan; Rabinowitz, Joshua D | Nature metabolism. | 2019 Mar; | 31058257 | |
| Reduced Repertoire of Cortical Microstates and Neuronal Ensembles in Medically Induced Loss of Consciousness. | Wenzel, Michael; Han, Shuting; Smith, Elliot H; Hoel, Erik; Greger, Bradley; House, Paul A; Yuste, Rafael | Cell systems. | 2019 May 22; | 31054810 | |
| Fungus Among Us: The Frenemies Within. | Aggor, Felix E Y; Way, Sing Sing; Gaffen, Sarah L | Trends in immunology. | 2019 Jun; | 31053496 | |
| Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi. | Tang, Man-Cheng; Fischer, Curt R; Chari, Jason V; Tan, Dan; Suresh, Sundari; Chu, Angela; Miranda, Molly; Smith, Justin; Zhang, Zhuan; Garg, Neil K; St Onge, Robert P; Tang, Yi | Journal of the American Chemical Society. | 2019 May 22; | 31051070 | |
| Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity. | Zhang, Nan; Czepielewski, Rafael S; Jarjour, Nicholas N; Erlich, Emma C; Esaulova, Ekaterina; Saunders, Brian T; Grover, Steven P; Cleuren, Audrey C; Broze, George J; Edelson, Brian T; Mackman, Nigel; Zinselmeyer, Bernd H; Randolph, Gwendalyn J | The Journal of experimental medicine. | 2019 Jun 03; | 31048328 | |
| Three New Cs for CRISPR: Collateral, Communicate, Cooperate. | Varble, Andrew; Marraffini, Luciano A | Trends in genetics : TIG. | 2019 Jun; | 31036344 | |
| Papain-based Single Cell Isolation of Primary Murine Brain Endothelial Cells Using Flow Cytometry. | Yousef, Hanadie; Czupalla, Cathrin J; Lee, Davis; Butcher, Eugene C; Wyss-Coray, Tony | Bio-protocol. | 2018 Nov 20; | 31032379 | |
| Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue. | Nagai, Jun; Rajbhandari, Abha K; Gangwani, Mohitkumar R; Hachisuka, Ayaka; Coppola, Giovanni; Masmanidis, Sotiris C; Fanselow, Michael S; Khakh, Baljit S | Cell. | 2019 May 16; | 31031006 | |
| Near-Infrared-II Molecular Dyes for Cancer Imaging and Surgery. | Zhu, Shoujun; Tian, Rui; Antaris, Alexander L; Chen, Xiaoyuan; Dai, Hongjie | Advanced materials (Deerfield Beach, Fla.). | 2019 Jun; | 31025403 | |
| In Situ Modification of Tissue Stem and Progenitor Cell Genomes. | Goldstein, Jill M; Tabebordbar, Mohammadsharif; Zhu, Kexian; Wang, Leo D; Messemer, Kathleen A; Peacker, Bryan; Ashrafi Kakhki, Sara; Gonzalez-Celeiro, Meryem; Shwartz, Yulia; Cheng, Jason K W; Xiao, Ru; Barungi, Trisha; Albright, Charles; Hsu, Ya-Chieh; | Cell reports. | 2019 Apr 23; | 31018138 | |
| Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. | Tarantini, Stefano; Valcarcel-Ares, Marta Noa; Toth, Peter; Yabluchanskiy, Andriy; Tucsek, Zsuzsanna; Kiss, Tamas; Hertelendy, Peter; Kinter, Michael; Ballabh, Praveen; Süle, Zoltán; Farkas, Eszter; Baur, Joseph A; Sinclair, David A; Csiszar, Anna; Ungvari, Zoltan | Redox biology. | 2019 Apr 10; | 31015147 | |
| A Common Neuroendocrine Substrate for Diverse General Anesthetics and Sleep. | Jiang-Xie, Li-Feng; Yin, Luping; Zhao, Shengli; Prevosto, Vincent; Han, Bao-Xia; Dzirasa, Kafui; Wang, Fan | Neuron. | 2019 Apr 05; | 31006556 | |
| Nanowired Bioelectric Interfaces. | Tian, Bozhi; Lieber, Charles M | Chemical reviews. | 2019 Apr 17; | 30995019 | |
| The Bacterivore's Solution: Fight and Flight to Promote Survival. | Lee, Yi-Tang; Wang, Meng C | Developmental cell. | 2019 Apr 08; | 30965036 | |
| Small molecule targeting of RNA structures in neurological disorders. | Angelbello, Alicia J; Chen, Jonathan L; Disney, Matthew D | Annals of the New York Academy of Sciences. | 2019 Apr 09; | 30964958 | |
| Does Autophagy Promote Longevity? It Depends. | Savini, Marzia; Wang, Meng C | Cell. | 2019 Apr 04; | 30951663 | |
| Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. | Lee, Shih-Han; Mayr, Christine | Molecular cell. | 2019 May 16; | 30948266 | |
| CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. | Pluvinage, John V; Haney, Michael S; Smith, Benjamin A H; Sun, Jerry; Iram, Tal; Bonanno, Liana; Li, Lulin; Lee, Davis P; Morgens, David W; Yang, Andrew C; Shuken, Steven R; Gate, David; Scott, Madeleine; Khatri, Purvesh; Luo, Jian; Bertozzi, Carolyn R; B | Nature. | 2019 Apr; | 30944478 | |
| Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease. | Amano, Hisayuki; Chaudhury, Arindam; Rodriguez-Aguayo, Cristian; Lu, Lan; Akhanov, Viktor; Catic, Andre; Popov, Yury V; Verdin, Eric; Johnson, Hannah; Stossi, Fabio; Sinclair, David A; Nakamaru-Ogiso, Eiko; Lopez-Berestein, Gabriel; Chang, Jeffrey T; Neilson, Joel R; Meeker, Alan; Finegold, Milton; Baur, Joseph A; Sahin, Ergun | Cell metabolism. | 2019 Mar 20; | 30930169 | |
| Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. | Thyme, Summer B; Pieper, Lindsey M; Li, Eric H; Pandey, Shristi; Wang, Yiqun; Morris, Nathan S; Sha, Carrie; Choi, Joo Won; Herrera, Kristian J; Soucy, Edward R; Zimmerman, Steve; Randlett, Owen; Greenwood, Joel; McCarroll, Steven A; Schier, Alexander F | Cell. | 2019 Apr 04; | 30929901 | |
| Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model. | Angelbello, Alicia J; Rzuczek, Suzanne G; Mckee, Kendra K; Chen, Jonathan L; Olafson, Hailey; Cameron, Michael D; Moss, Walter N; Wang, Eric T; Disney, Matthew D | Proceedings of the National Academy of Sciences of the United States of America. | 2019 Apr 16; | 30926669 | |
| Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States. | Wei, Spencer C; Sharma, Roshan; Anang, Nana-Ama A S; Levine, Jacob H; Zhao, Yang; Mancuso, James J; Setty, Manu; Sharma, Padmanee; Wang, Jing; Pe'er, Dana; Allison, James P | Immunity. | 2019 Apr 16; | 30926234 | |
| High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage. | Slaymaker, Ian M; Mesa, Pablo; Kellner, Max J; Kannan, Soumya; Brignole, Edward; Koob, Jeremy; Feliciano, Patricia R; Stella, Stefano; Abudayyeh, Omar O; Gootenberg, Jonathan S; Strecker, Jonathan; Montoya, Guillermo; Zhang, Feng | Cell reports. | 2019 Mar 26; | 30917325 | |
| Prometheus Unbound in Ya(p) Heart. | Buikema, Jan W; Wu, Sean M | Developmental cell. | 2019 Mar 25; | 30913402 | |
| Targeting RNA with Small Molecules To Capture Opportunities at the Intersection of Chemistry, Biology, and Medicine. | Disney, Matthew D | Journal of the American Chemical Society. | 2019 May 01; | 30896935 | |
| Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide. | Bertoldo, M J; Uddin, G M; Youngson, N A; Agapiou, D; Walters, K A; Sinclair, D A; Morris, M J; Gilchrist, R B | Human reproduction open. | 2018; | 30895251 | |
| Modeling Patient-Derived Glioblastoma with Cerebral Organoids. | Linkous, Amanda; Balamatsias, Demosthenes; Snuderl, Matija; Edwards, Lincoln; Miyaguchi, Ken; Milner, Teresa; Reich, Batsheva; Cohen-Gould, Leona; Storaska, Andrew; Nakayama, Yasumi; Schenkein, Emily; Singhania, Richa; Cirigliano, Stefano; Magdeldin, Tari | Cell reports. | 2019 Mar 19; | 30893594 | |
| How face perception unfolds over time. | Dobs, Katharina; Isik, Leyla; Pantazis, Dimitrios; Kanwisher, Nancy | Nature communications. | 2019 03 19; | 30890707 | |
| Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci. | Varble, Andrew; Meaden, Sean; Barrangou, Rodolphe; Westra, Edze R; Marraffini, Luciano A | Nature microbiology. | 2019 Jun; | 30886355 | |
| Studying interactions between dendritic cells and T cells in vivo. | Chudnovskiy, Aleksey; Pasqual, Giulia; Victora, Gabriel D | Current opinion in immunology. | 2019 Mar 15; | 30884422 | |
| Lymphatic network remodeling after small bowel resection. | Onufer, Emily J; Czepielewski, Rafael; Seiler, Kristen M; Erlich, Emma; Courtney, Cathleen M; Bustos, Aiza; Randolph, Gwendalyn J; Warner, Brad W | Journal of pediatric surgery. | 2019 Feb 28; | 30879758 | |
| Neural mechanisms of social homeostasis. | Matthews, Gillian A; Tye, Kay M | Annals of the New York Academy of Sciences. | 2019 Mar 15; | 30875095 | |
| Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses. | Shao, Tzu-Yu; Ang, W X Gladys; Jiang, Tony T; Huang, Felicia Scaggs; Andersen, Heidi; Kinder, Jeremy M; Pham, Giang; Burg, Ashley R; Ruff, Brandy; Gonzalez, Tammy; Khurana Hershey, Gurjit K; Haslam, David B; Way, Sing Sing | Cell host & microbe. | 2019 Mar 13; | 30870622 | |
| Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups. | Rueda, Oscar M; Sammut, Stephen-John; Seoane, Jose A; Chin, Suet-Feung; Caswell-Jin, Jennifer L; Callari, Maurizio; Batra, Rajbir; Pereira, Bernard; Bruna, Alejandra; Ali, H Raza; Provenzano, Elena; Liu, Bin; Parisien, Michelle; Gillett, Cheryl; McKinney, Steven; Green, Andrew R; Murphy, Leigh; Purushotham, Arnie; Ellis, Ian O; Pharoah, Paul D; Rueda, Cristina; Aparicio, Samuel; Caldas, Carlos; Curtis, Christina | Nature. | 2019 Mar; | 30867590 | |
| TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2. | Kotov, Dmitri I; Mitchell, Jason S; Pengo, Thomas; Ruedl, Christiane; Way, Sing Sing; Langlois, Ryan A; Fife, Brian T; Jenkins, Marc K | Journal of immunology (Baltimore, Md. : 1950). | 2019 May 01; | 30858199 | |
| Multiple basal cell carcinomas in a patient with myotonic dystrophy type 1. | Feng, Jessica; LaChance, Avery; Sinclair, David A; Asgari, Maryam M | BMJ case reports. | 2019 Mar 08; | 30852496 | |
| Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia. | Prakosa, Adityo; Arevalo, Hermenegild J; Deng, Dongdong; Boyle, Patrick M; Nikolov, Plamen P; Ashikaga, Hiroshi; Blauer, Joshua Je; Ghafoori, Elyar; Park, Carolyn J; Blake 3rd, Robert C; Han, Frederick T; MacLeod, Rob S; Halperin, Henry R; Callans, David J; Ranjan, Ravi; Chrispin, Jonathan; Nazarian, Saman; Trayanova, Natalia A | Nature biomedical engineering. | 2018 Oct; | 30847259 | |
| Developmental origins and emerging therapeutic opportunities for childhood cancer. | Filbin, Mariella; Monje, Michelle | Nature medicine. | 2019 03; | 30842674 | |
| Computational Identification of Ventricular Arrhythmia Risk in Pediatric Myocarditis. | Cartoski, Mark J; Nikolov, Plamen P; Prakosa, Adityo; Boyle, Patrick M; Spevak, Philip J; Trayanova, Natalia A | Pediatric cardiology. | 2019 Apr; | 30840104 | |
| Spastin is a dual-function enzyme that severs microtubules and promotes their regrowth to increase the number and mass of microtubules. | Kuo, Yin-Wei; Trottier, Olivier; Mahamdeh, Mohammed; Howard, Jonathon | Proceedings of the National Academy of Sciences of the United States of America. | 2019 Mar 19; | 30837315 | |
| Novel electrode technologies for neural recordings. | Hong, Guosong; Lieber, Charles M | Nature reviews. Neuroscience. | 2019 Mar 04; | 30833706 | |
| Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling. | Pan, Liqiang; Fu, Tian-Min; Zhao, Wenbin; Zhao, Linlin; Chen, Wen; Qiu, Chixiao; Liu, Wenhui; Liu, Zhijun; Piai, Alessandro; Fu, Qingshan; Chen, Shuqing; Wu, Hao; Chou, James J | Cell. | 2019 Mar 07; | 30827683 | |
| Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. | van Galen, Peter; Hovestadt, Volker; Wadsworth Ii, Marc H; Hughes, Travis K; Griffin, Gabriel K; Battaglia, Sofia; Verga, Julia A; Stephansky, Jason; Pastika, Timothy J; Lombardi Story, Jennifer; Pinkus, Geraldine S; Pozdnyakova, Olga; Galinsky, Ilene; Stone, Richard M; Graubert, Timothy A; Shalek, Alex K; Aster, Jon C; Lane, Andrew A; Bernstein, Bradley E | Cell. | 2019 Mar 07; | 30827681 | |
| An integrative computational architecture for object-driven cortex. | Yildirim, Ilker; Wu, Jiajun; Kanwisher, Nancy; Tenenbaum, Joshua | Current opinion in neurobiology. | 2019 Feb 27; | 30825704 | |
| Epigenetic changes during aging and their reprogramming potential. | Kane, Alice E; Sinclair, David A | Critical reviews in biochemistry and molecular biology. | 2019 Feb; | 30822165 | |
| Bioinspired neuron-like electronics. | Yang, Xiao; Zhou, Tao; Zwang, Theodore J; Hong, Guosong; Zhao, Yunlong; Viveros, Robert D; Fu, Tian-Ming; Gao, Teng; Lieber, Charles M | Nature materials. | 2019 Feb 25; | 30804509 | |
| Phosphate graphene as an intrinsically osteoinductive scaffold for stem cell-driven bone regeneration. | Arnold, Anne M; Holt, Brian D; Daneshmandi, Leila; Laurencin, Cato T; Sydlik, Stefanie A | Proceedings of the National Academy of Sciences of the United States of America. | 2019 03 12; | 30796184 | |
| Serine Metabolism Supports Macrophage IL-1? Production. | Rodriguez, Arianne E; Ducker, Gregory S; Billingham, Leah K; Martinez, Carlos A; Mainolfi, Nello; Suri, Vipin; Friedman, Adam; Manfredi, Mark G; Weinberg, Samuel E; Rabinowitz, Joshua D; Chandel, Navdeep S | Cell metabolism. | 2019 Apr 02; | 30773464 | |
| (Ph)ighting Phages: How Bacteria Resist Their Parasites. | Rostøl, Jakob T; Marraffini, Luciano | Cell host & microbe. | 2019 Feb 13; | 30763533 | |
| A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP. | Lobas, Mark A; Tao, Rongkun; Nagai, Jun; Kronschläger, Mira T; Borden, Philip M; Marvin, Jonathan S; Looger, Loren L; Khakh, Baljit S | Nature communications. | 2019 Feb 12; | 30755613 | |
| The role of personalized atrial modeling in understanding atrial fibrillation mechanisms and improving treatment. | Aronis, Konstantinos N; Ali, Rheeda; Trayanova, Natalia A | International journal of cardiology. | 2019 Jan 31; | 30755334 | |
| L1 drives IFN in senescent cells and promotes age-associated inflammation. | De Cecco, Marco; Ito, Takahiro; Petrashen, Anna P; Elias, Amy E; Skvir, Nicholas J; Criscione, Steven W; Caligiana, Alberto; Brocculi, Greta; Adney, Emily M; Boeke, Jef D; Le, Oanh; Beauséjour, Christian; Ambati, Jayakrishna; Ambati, Kameshwari; Simon, Matthew; Seluanov, Andrei; Gorbunova, Vera; Slagboom, P Eline; Helfand, Stephen L; Neretti, Nicola; Sedivy, John M | Nature. | 2019 02; | 30728521 | |
| Genome-wide colocalization of RNA-DNA interactions and fusion RNA pairs. | Yan, Zhangming; Huang, Norman; Wu, Weixin; Chen, Weizhong; Jiang, Yiqun; Chen, Jingyao; Huang, Xuerui; Wen, Xingzhao; Xu, Jie; Jin, Qiushi; Zhang, Kang; Chen, Zhen; Chien, Shu; Zhong, Sheng | Proceedings of the National Academy of Sciences of the United States of America. | 2019 Feb 19; | 30718424 | |
| Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity. | Ramachandran, Prasanna V; Savini, Marzia; Folick, Andrew K; Hu, Kuang; Masand, Ruchi; Graham, Brett H; Wang, Meng C | Developmental cell. | 2019 Jan 23; | 30713071 | |
| Spacer Acquisition Rates Determine the Immunological Diversity of the Type II CRISPR-Cas Immune Response. | Heler, Robert; Wright, Addison V; Vucelja, Marija; Doudna, Jennifer A; Marraffini, Luciano A | Cell host & microbe. | 2019 02 13; | 30709780 | |
| Transcytosis at the blood-brain barrier. | Ayloo, Swathi; Gu, Chenghua | Current opinion in neurobiology. | 2019 Jan 29; | 30708291 | |
| Intersectional monosynaptic tracing for dissecting subtype-specific organization of GABAergic interneuron inputs. | Yetman, Michael J; Washburn, Eric; Hyun, Jung Ho; Osakada, Fumitaka; Hayano, Yasufumi; Zeng, Hongkui; Callaway, Edward M; Kwon, Hyung-Bae; Taniguchi, Hiroki | Nature neuroscience. | 2019 Jan 28; | 30692688 | |
| Non-specific degradation of transcripts promotes plasmid clearance during type III-A CRISPR-Cas immunity. | Rostøl, Jakob T; Marraffini, Luciano A | Nature microbiology. | 2019 Jan 28; | 30692669 | |
| SERPINB1-mediated checkpoint of inflammatory caspase activation. | Choi, Youn Jung; Kim, Stephanie; Choi, Younho; Nielsen, Travis B; Yan, Jun; Lu, Alvin; Ruan, Jianbin; Lee, Hye-Ra; Wu, Hao; Spellberg, Brad; Jung, Jae U | Nature immunology. | 2019 Jan 28; | 30692621 | |
| Nanofiber/Microsphere Hybrid Matrices In Vivo for Bone Regenerative Engineering: A Preliminary Report. | Nelson, Clarke; Khan, Yusuf; Laurencin, Cato T | Regenerative engineering and translational medicine. | 2018 Sep; | 30687776 | |
| Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4). | Wang, Li; Ferrao, Ryan; Li, Qiubai; Hatcher, John M; Choi, Hwan Geun; Buhrlage, Sara J; Gray, Nathanael S; Wu, Hao | The Journal of biological chemistry. | 2019 Jan 24; | 30679311 | |
| New insights on the cardiac safety factor: Unraveling the relationship between conduction velocity and robustness of propagation. | Boyle, Patrick M; Franceschi, William H; Constantin, Marion; Hawks, Claudia; Desplantez, Thomas; Trayanova, Natalia A; Vigmond, Edward J | Journal of molecular and cellular cardiology. | 2019 Mar; | 30677394 | |
| Molecular mechanism for NLRP6 inflammasome assembly and activation. | Shen, Chen; Lu, Alvin; Xie, Wen Jun; Ruan, Jianbin; Negro, Roberto; Egelman, Edward H; Fu, Tian-Min; Wu, Hao | Proceedings of the National Academy of Sciences of the United States of America. | 2019 Feb 05; | 30674671 | |
| Engineering of CRISPR-Cas12b for human genome editing. | Strecker, Jonathan; Jones, Sara; Koopal, Balwina; Schmid-Burgk, Jonathan; Zetsche, Bernd; Gao, Linyi; Makarova, Kira S; Koonin, Eugene V; Zhang, Feng | Nature communications. | 2019 01 22; | 30670702 | |
| Mimicry by a viral RHIM. | Mompeán, Miguel; Bozkurt, Gunes; Wu, Hao | EMBO reports. | 2019 Feb; | 30665943 | |
| Intensiometric biosensors visualize the activity of multiple small GTPases in vivo. | Kim, Jihoon; Lee, Sangkyu; Jung, Kanghoon; Oh, Won Chan; Kim, Nury; Son, Seungkyu; Jo, YoungJu; Kwon, Hyung-Bae; Do Heo, Won | Nature communications. | 2019 01 14; | 30643148 | |
| Crystal structure of the WD40 domain dimer of LRRK2. | Zhang, Pengfei; Fan, Ying; Ru, Heng; Wang, Li; Magupalli, Venkat Giri; Taylor, Susan S; Alessi, Dario R; Wu, Hao | Proceedings of the National Academy of Sciences of the United States of America. | 2019 Jan 29; | 30635421 | |
| The usual suspects, dopamine and alpha-synuclein, conspire to cause neurodegeneration. | Mor, Danielle E; Daniels, Malcolm J; Ischiropoulos, Harry | Movement disorders : official journal of the Movement Disorder Society. | 2019 Feb; | 30633814 | |
| Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. | Poulopoulos, Alexandros; Murphy, Alexander J; Ozkan, Abdulkadir; Davis, Patrick; Hatch, John; Kirchner, Rory; Macklis, Jeffrey D | Nature. | 2019 01; | 30626971 | |
| A likelihood approach to testing hypotheses on the co-evolution of epigenome and genome. | Lu, Jia; Cao, Xiaoyi; Zhong, Sheng | PLoS computational biology. | 2018 Dec; | 30586383 | |
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| RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling. | Evans, Paul R; Parra-Bueno, Paula; Smirnov, Michael S; Lustberg, Daniel J; Dudek, Serena M; Hepler, John R; Yasuda, Ryohei | eNeuro. | 2018 May-Jun; | 29911178 | |
| Limited Macrophage Positional Dynamics in Progressing or Regressing Murine Atherosclerotic Plaques. | Williams, Jesse W; Martel, Catherine; Potteaux, Stephane; Esaulova, Ekaterina; Ingersoll, Molly A; Elvington, Andrew; Saunders, Brian T; Huang, Li-Hao; Habenicht, Andreas J; Zinselmeyer, Bernd H; Randolph, Gwendalyn J | Arteriosclerosis, thrombosis, and vascular biology. | ; | 29903736 | |
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| Bright quantum dots emitting at ?1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging. | Zhang, Mingxi; Yue, Jingying; Cui, Ran; Ma, Zhuoran; Wan, Hao; Wang, Feifei; Zhu, Shoujun; Zhou, Ying; Kuang, Yun; Zhong, Yeteng; Pang, Dai-Wen; Dai, Hongjie | Proceedings of the National Academy of Sciences of the United States of America. | 2018 06 26; | 29891702 | |
| Role of 3-Dimensional Architecture of Scar and Surviving Tissue in Ventricular Tachycardia: Insights From High-Resolution Ex Vivo Porcine Models. | Pashakhanloo, Farhad; Herzka, Daniel A; Halperin, Henry; McVeigh, Elliot R; Trayanova, Natalia A | Circulation. Arrhythmia and electrophysiology. | ; | 29880529 | |
| A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice. | Deshpande, Neha R; Uhrlaub, Jennifer L; Way, Sing Sing; Nikolich-?ugich, Janko; Kuhns, Michael S | PloS one. | 2018; | 29864157 | |
| Light sheet theta microscopy for rapid high-resolution imaging of large biological samples. | Migliori, Bianca; Datta, Malika S; Dupre, Christophe; Apak, Mehmet C; Asano, Shoh; Gao, Ruixuan; Boyden, Edward S; Hermanson, Ola; Yuste, Rafael; Tomer, Raju | BMC biology. | 2018 May 29; | 29843722 | |
| Quantifying the uncertainty in model parameters using Gaussian process-based Markov chain Monte Carlo in cardiac electrophysiology. | Dhamala, Jwala; Arevalo, Hermenegild J; Sapp, John; Horácek, B Milan; Wu, Katherine C; Trayanova, Natalia A; Wang, Linwei | Medical image analysis. | ; | 29843078 | |
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| A Near-Complete Spatial Map of Olfactory Receptors in the Mouse Main Olfactory Epithelium. | Tan, Longzhi; Xie, Xiaoliang Sunney | Chemical senses. | 2018 Jul 05; | 29796642 | |
| Multiplex assessment of protein variant abundance by massively parallel sequencing. | Matreyek, Kenneth A; Starita, Lea M; Stephany, Jason J; Martin, Beth; Chiasson, Melissa A; Gray, Vanessa E; Kircher, Martin; Khechaduri, Arineh; Dines, Jennifer N; Hause, Ronald J; Bhatia, Smita; Evans, William E; Relling, Mary V; Yang, Wenjian; Shendure, | Nature genetics. | 2018 Jun; | 29785012 | |
| Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. | Yang, Jason D; Mott, Daniel; Sutiwisesak, Rujapak; Lu, Yu-Jung; Raso, Fiona; Stowell, Britni; Babunovic, Greg Hunter; Lee, Jinhee; Carpenter, Steve M; Way, Sing Sing; Fortune, Sarah M; Behar, Samuel M | PLoS pathogens. | 2018 02; | 29782535 | |
| Making, Testing, and Using Potassium Ion Selective Microelectrodes in Tissue Slices of Adult Brain. | Octeau, J Christopher; Faas, Guido; Mody, Istvan; Khakh, Baljit S | Journal of visualized experiments : JoVE. | 2018 05 07; | 29781998 | |
| Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics. | Yang, Andrew C; du Bois, Haley; Olsson, Niclas; Gate, David; Lehallier, Benoit; Berdnik, Daniela; Brewer, Kyle D; Bertozzi, Carolyn R; Elias, Joshua E; Wyss-Coray, Tony | Journal of the American Chemical Society. | 2018 06 13; | 29775058 | |
| Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9. | Akhmetov, Azat; Laurent, Jon M; Gollihar, Jimmy; Gardner, Elizabeth C; Garge, Riddhiman K; Ellington, Andrew D; Kachroo, Aashiq H; Marcotte, Edward M | Bio-protocol. | ; | 29770349 | |
| Role of inhibitory control in modulating focal seizure spread. | Liou, Jyun-You; Ma, Hongtao; Wenzel, Michael; Zhao, Mingrui; Baird-Daniel, Eliza; Smith, Elliot H; Daniel, Andy; Emerson, Ronald; Yuste, Rafael; Schwartz, Theodore H; Schevon, Catherine A | Brain : a journal of neurology. | 2018 Jul 01; | 29757347 | |
| A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization. | Hansen, Maike M K; Wen, Winnie Y; Ingerman, Elena; Razooky, Brandon S; Thompson, Cassandra E; Dar, Roy D; Chin, Charles W; Simpson, Michael L; Weinberger, Leor S | Cell. | 2018 Jun 14; | 29754821 | |
| Fueling thought: Management of glycolysis and oxidative phosphorylation in neuronal metabolism. | Yellen, Gary | The Journal of cell biology. | 2018 Jul 02; | 29752396 | |
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| Diverse reprogramming codes for neuronal identity. | Tsunemoto, Rachel; Lee, Sohyon; Sz?cs, Attila; Chubukov, Pavel; Sokolova, Irina; Blanchard, Joel W; Eade, Kevin T; Bruggemann, Jacob; Wu, Chunlei; Torkamani, Ali; Sanna, Pietro Paolo; Baldwin, Kristin K | Nature. | 2018 05; | 29743677 | |
| A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish. | Haesemeyer, Martin; Robson, Drew N; Li, Jennifer M; Schier, Alexander F; Engert, Florian | Neuron. | 2018 May 16; | 29731253 | |
| Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning. | Allsop, Stephen A; Wichmann, Romy; Mills, Fergil; Burgos-Robles, Anthony; Chang, Chia-Jung; Felix-Ortiz, Ada C; Vienne, Alienor; Beyeler, Anna; Izadmehr, Ehsan M; Glober, Gordon; Cum, Meghan I; Stergiadou, Johanna; Anandalingam, Kavitha K; Farris, Kathryn; Namburi, Praneeth; Leppla, Christopher A; Weddington, Javier C; Nieh, Edward H; Smith, Anne C; Ba, Demba; Brown, Emery N; Tye, Kay M | Cell. | 2018 May 31; | 29731170 | |
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| Microbial Genetic Composition Tunes Host Longevity. | Han, Bing; Sivaramakrishnan, Priya; Lin, Chih-Chun J; Neve, Isaiah A A; He, Jingquan; Tay, Li Wei Rachel; Sowa, Jessica N; Sizovs, Antons; Du, Guangwei; Wang, Jin; Herman, Christophe; Wang, Meng C | Cell. | 2018 May 03; | 29727664 | |
| Widespread intronic polyadenylation diversifies immune cell transcriptomes. | Singh, Irtisha; Lee, Shih-Han; Sperling, Adam S; Samur, Mehmet K; Tai, Yu-Tzu; Fulciniti, Mariateresa; Munshi, Nikhil C; Mayr, Christine; Leslie, Christina S | Nature communications. | 2018 Apr 30; | 29712909 | |
| Stage-specific Effects of Bioactive Lipids on Human iPSC Cardiac Differentiation and Cardiomyocyte Proliferation. | Scientific reports. | 2018 Apr 26; | 29700394 | ||
| Field-deployable viral diagnostics using CRISPR-Cas13. | Myhrvold, Cameron; Freije, Catherine A; Gootenberg, Jonathan S; Abudayyeh, Omar O; Metsky, Hayden C; Durbin, Ann F; Kellner, Max J; Tan, Amanda L; Paul, Lauren M; Parham, Leda A; Garcia, Kimberly F; Barnes, Kayla G; Chak, Bridget; Mondini, Adriano; Noguei | Science (New York, N.Y.). | 2018 04 27; | 29700266 | |
| Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis. | Science (New York, N.Y.). | 2018 06 01; | 29700225 | ||
| Cryo-EM structure of the gasdermin A3 membrane pore. | Nature. | 2018 May; | 29695864 | ||
| Bridging barriers: a comparative look at the blood-brain barrier across organisms. | O'Brown, Natasha M; Pfau, Sarah J; Gu, Chenghua | Genes & development. | 2018 04 01; | 29692355 | |
| Structural Biology: Piezo Senses Tension through Curvature. | Liang, Xin; Howard, Jonathon | Current biology : CB. | 2018 Apr 23; | 29689211 | |
| Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. | Liu, Ling; Su, Xiaoyang; Quinn 3rd, William J; Hui, Sheng; Krukenberg, Kristin; Frederick, David W; Redpath, Philip; Zhan, Le; Chellappa, Karthikeyani; White, Eileen; Migaud, Marie; Mitchison, Timothy J; Baur, Joseph A; Rabinowitz, Joshua D | Cell metabolism. | 2018 May 01; | 29685734 | |
| Molecular Cancer Imaging in the Second Near-Infrared Window Using a Renal-Excreted NIR-II Fluorophore-Peptide Probe. | Wang, Weizhi; Ma, Zhuoran; Zhu, Shoujun; Wan, Hao; Yue, Jingying; Ma, Huilong; Ma, Rui; Yang, Qinglai; Wang, Zihua; Li, Qian; Qian, Yixia; Yue, Chunyan; Wang, Yuehua; Fan, Linyang; Zhong, Yeteng; Zhou, Ying; Gao, Hongpeng; Ruan, Junshan; Hu, Zhiyuan; Liang, Yongye; Dai, Hongjie | Advanced materials (Deerfield Beach, Fla.). | 2018 May; | 29682821 | |
| The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex. | Mompeán, Miguel; Li, Wenbo; Li, Jixi; Laage, Ségolène; Siemer, Ansgar B; Bozkurt, Gunes; Wu, Hao; McDermott, Ann E | Cell. | 2018 May 17; | 29681455 | |
| Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. | Filbin, Mariella G; Tirosh, Itay; Hovestadt, Volker; Shaw, McKenzie L; Escalante, Leah E; Mathewson, Nathan D; Neftel, Cyril; Frank, Nelli; Pelton, Kristine; Hebert, Christine M; Haberler, Christine; Yizhak, Keren; Gojo, Johannes; Egervari, Kristof; Mount | Science (New York, N.Y.). | 2018 04 20; | 29674595 | |
| Amelioration of Neurosensory Structure and Function in Animal and Cellular Models of a Congenital Blindness. | Song, Ji Yun; Aravand, Puya; Nikonov, Sergei; Leo, Lanfranco; Lyubarsky, Arkady; Bennicelli, Jeannette L; Pan, Jieyan; Wei, Zhangyong; Shpylchak, Ivan; Herrera, Pamela; Bennett, Daniel J; Commins, Nicoletta; Maguire, Albert M; Pham, Jennifer; den Hollande | Molecular therapy : the journal of the American Society of Gene Therapy. | 2018 Mar 21; | 29673930 | |
| Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity. | Ma, Siming; Avanesov, Andrei S; Porter, Emily; Lee, Byung Cheon; Mariotti, Marco; Zemskaya, Nadezhda; Guigo, Roderic; Moskalev, Alexey A; Gladyshev, Vadim N | Aging cell. | 2018 Apr 19; | 29671950 | |
| Holographic imaging and photostimulation of neural activity. | Yang, Weijian; Yuste, Rafael | Current opinion in neurobiology. | 2018 Jun; | 29660600 | |
| Design of a sustainable prepolarizing magnetic resonance imaging system for infant hydrocephalus. | Obungoloch, Johnes; Harper, Joshua R; Consevage, Steven; Savukov, Igor M; Neuberger, Thomas; Tadigadapa, Srinivas; Schiff, Steven J | Magma (New York, N.Y.). | 2018 Apr 11; | 29644479 | |
| Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism. | Al-Khalidi, Rasha; Panicucci, Chiara; Cox, Paul; Chira, Natalia; Róg, Justyna; Young, Christopher N J; McGeehan, Rhiannon E; Ambati, Kameshwari; Ambati, Jayakrishna; Zab?ocki, Krzysztof; Gazzerro, Elisabetta; Arkle, Stephen; Bruno, Claudio; Górecki, Dariusz C | Acta neuropathologica communications. | 2018 04 11; | 29642926 | |
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| An Optical Neuron-Astrocyte Proximity Assay at Synaptic Distance Scales. | Octeau, J Christopher; Chai, Hua; Jiang, Ruotian; Bonanno, Shivan L; Martin, Kelsey C; Khakh, Baljit S | Neuron. | 2018 Apr 04; | 29621490 | |
| Complete biosynthesis of noscapine and halogenated alkaloids in yeast. | Li, Yanran; Li, Sijin; Thodey, Kate; Trenchard, Isis; Cravens, Aaron; Smolke, Christina D | Proceedings of the National Academy of Sciences of the United States of America. | 2018 Apr 24; | 29610307 | |
| Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain. | Raj, Bushra; Wagner, Daniel E; McKenna, Aaron; Pandey, Shristi; Klein, Allon M; Shendure, Jay; Gagnon, James A; Schier, Alexander F | Nature biotechnology. | 2018 Jun; | 29608178 | |
| Interbrain cortical synchronization encodes multiple aspects of social interactions in monkey pairs. | Tseng, Po-He; Rajangam, Sankaranarayani; Lehew, Gary; Lebedev, Mikhail A; Nicolelis, Miguel A L | Scientific reports. | 2018 Mar 29; | 29599529 | |
| Fates Aligned: Origins and Mechanisms of Ventricular Conduction System and Ventricular Wall Development. | Goodyer, William R; Wu, Sean M | Pediatric cardiology. | 2018 Mar 28; | 29594502 | |
| Deconstructing the pluripotency gene regulatory network. | Li, Mo; Izpisua Belmonte, Juan Carlos | Nature cell biology. | 2018 04; | 29593328 | |
| Anti-CTLA-4 therapy requires an Fc domain for efficacy. | Ingram, Jessica R; Blomberg, Olga S; Rashidian, Mohammad; Ali, Lestat; Garforth, Scott; Fedorov, Elena; Fedorov, Alexander A; Bonanno, Jeffrey B; Le Gall, Camille; Crowley, Stephanie; Espinosa, Camilo; Biary, Tamara; Keliher, Edmund J; Weissleder, Ralph; | Proceedings of the National Academy of Sciences of the United States of America. | 2018 Apr 10; | 29581255 | |
| Reactivation of the Nkx2.5 cardiac enhancer after myocardial infarction does not presage myogenesis. | Deutsch, Marcus-André; Doppler, Stefanie A; Li, Xinghai; Lahm, Harald; Santamaria, Gianluca; Cuda, Giovanni; Eichhorn, Stefan; Ratschiller, Thomas; Dzilic, Elda; Dreßen, Martina; Eckart, Annekathrin; Stark, Konstantin; Massberg, Steffen; Bartels, Anna; Ri | Cardiovascular research. | 2018 Mar 20; | 29579159 | |
| Sirtuin activators and inhibitors: Promises, achievements, and challenges. | Dai, Han; Sinclair, David A; Ellis, James L; Steegborn, Clemens | Pharmacology & therapeutics. | 2018 Mar 22; | 29577959 | |
| Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq. | Pandey, Shristi; Shekhar, Karthik; Regev, Aviv; Schier, Alexander F | Current biology : CB. | 2018 Apr 02; | 29576475 | |
| Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction. | Sziráki, András; Tyshkovskiy, Alexander; Gladyshev, Vadim N | Aging cell. | 2018 Mar 25; | 29575528 | |
| The African turquoise killifish: A research organism to study vertebrate aging and diapause. | Hu, Chi-Kuo; Brunet, Anne | Aging cell. | 2018 Jun; | 29573324 | |
| Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging. | Das, Abhirup; Huang, George X; Bonkowski, Michael S; Longchamp, Alban; Li, Catherine; Schultz, Michael B; Kim, Lynn-Jee; Osborne, Brenna; Joshi, Sanket; Lu, Yuancheng; Treviño-Villarreal, Jose Humberto; Kang, Myung-Jin; Hung, Tzong-Tyng; Lee, Brendan; Wil | Cell. | 2018 Mar 22; | 29570999 | |
| Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production. | Longchamp, Alban; Mirabella, Teodelinda; Arduini, Alessandro; MacArthur, Michael R; Das, Abhirup; Treviño-Villarreal, J Humberto; Hine, Christopher; Ben-Sahra, Issam; Knudsen, Nelson H; Brace, Lear E; Reynolds, Justin; Mejia, Pedro; Tao, Ming; Sharma, Gau | Cell. | 2018 Mar 22; | 29570992 | |
| Economic burden of neonatal sepsis in sub-Saharan Africa. | Ranjeva, Sylvia L; Warf, Benjamin C; Schiff, Steven J | BMJ global health. | 2018; | 29564153 | |
| A bright organic NIR-II nanofluorophore for three-dimensional imaging into biological tissues. | Wan, Hao; Yue, Jingying; Zhu, Shoujun; Uno, Takaaki; Zhang, Xiaodong; Yang, Qinglai; Yu, Kuai; Hong, Guosong; Wang, Junying; Li, Lulin; Ma, Zhuoran; Gao, Hongpeng; Zhong, Yeteng; Su, Jessica; Antaris, Alexander L; Xia, Yan; Luo, Jian; Liang, Yongye; Dai, Hongjie | Nature communications. | 2018 Mar 21; | 29563581 | |
| A deep neural network to assess spontaneous pain from mouse facial expressions. | Tuttle, Alexander H; Molinaro, Mark J; Jethwa, Jasmine F; Sotocinal, Susana G; Prieto, Juan C; Styner, Martin A; Mogil, Jeffrey S; Zylka, Mark J | Molecular pain. | 2018 Jan-Dec; | 29546805 | |
| Personalized Imaging and Modeling Strategies for Arrhythmia Prevention and Therapy. | Trayanova, Natalia A; Boyle, Patrick M; Nikolov, Plamen P | Current opinion in biomedical engineering. | 2018 Mar; | 29546250 | |
| The cis-regulatory dynamics of embryonic development at single-cell resolution. | Cusanovich, Darren A; Reddington, James P; Garfield, David A; Daza, Riza M; Aghamirzaie, Delasa; Marco-Ferreres, Raquel; Pliner, Hannah A; Christiansen, Lena; Qiu, Xiaojie; Steemers, Frank J; Trapnell, Cole; Shendure, Jay; Furlong, Eileen E M | Nature. | 2018 Mar 22; | 29539636 | |
| The Biosynthesis of Lipooligosaccharide from Bacteroides thetaiotaomicron. | Jacobson, Amy N; Choudhury, Biswa P; Fischbach, Michael A | mBio. | 2018 Mar 13; | 29535205 | |
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| Tissue-like Neural Probes for Understanding and Modulating the Brain. | Hong, Guosong; Viveros, Robert D; Zwang, Theodore J; Yang, Xiao; Lieber, Charles M | Biochemistry. | 2018 Mar 19; | 29529359 | |
| Zinc transporters belonging to the Cation Diffusion Facilitator (CDF) family have complementary roles in transporting zinc out of the cytosol. | Choi, Sangyong; Hu, Ya-Mei; Corkins, Mark E; Palmer, Amy E; Bird, Amanda J | PLoS genetics. | 2018 03; | 29529046 | |
| How to Build a Bacterial Cell: MreB as the Foreman of E. coli Construction. | Shi, Handuo; Bratton, Benjamin P; Gitai, Zemer; Huang, Kerwyn Casey | Cell. | 2018 Mar 08; | 29522748 | |
| Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. | Mitchell, Sarah J; Bernier, Michel; Aon, Miguel A; Cortassa, Sonia; Kim, Eun Young; Fang, Evandro F; Palacios, Hector H; Ali, Ahmed; Navas-Enamorado, Ignacio; Di Francesco, Andrea; Kaiser, Tamzin A; Waltz, Tyler B; Zhang, Ning; Ellis, James L; Elliott, Pe | Cell metabolism. | 2018 Mar 06; | 29514072 | |
| Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. | Rajman, Luis; Chwalek, Karolina; Sinclair, David A | Cell metabolism. | 2018 Mar 06; | 29514064 | |
| Toward a universal decoder of linguistic meaning from brain activation. | Pereira, Francisco; Lou, Bin; Pritchett, Brianna; Ritter, Samuel; Gershman, Samuel J; Kanwisher, Nancy; Botvinick, Matthew; Fedorenko, Evelina | Nature communications. | 2018 03 06; | 29511192 | |
| Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. | Wang, Guangchuan; Chow, Ryan D; Ye, Lupeng; Guzman, Christopher D; Dai, Xiaoyun; Dong, Matthew B; Zhang, Feng; Sharp, Phillip A; Platt, Randall J; Chen, Sidi | Science advances. | 2018 02; | 29503867 | |
| Neuronal regulation of longevity by staying cool. | Lin, Chih-Chun J; Neve, Isaiah A A; Wang, Meng C | Genes & development. | ; | 29491133 | |
| A Phase II Study of Tumor Ablation in Patients with Metastatic Sarcoma Stable on Chemotherapy. | Hirbe, Angela C; Jennings, Jack; Saad, Nael; Giardina, Joseph D; Tao, Yu; Luo, Jingqin; Berry, Shellie; Toeniskoetter, Jacqui; Van Tine, Brian A | The oncologist. | 2018 Jul; | 29487221 | |
| A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters. | Piatkevich, Kiryl D; Jung, Erica E; Straub, Christoph; Linghu, Changyang; Park, Demian; Suk, Ho-Jun; Hochbaum, Daniel R; Goodwin, Daniel; Pnevmatikakis, Eftychios; Pak, Nikita; Kawashima, Takashi; Yang, Chao-Tsung; Rhoades, Jeffrey L; Shemesh, Or; Asano, Shoh; Yoon, Young-Gyu; Freifeld, Limor; Saulnier, Jessica L; Riegler, Clemens; Engert, Florian; Hughes, Thom; Drobizhev, Mikhail; Szabo, Balint; Ahrens, Misha B; Flavell, Steven W; Sabatini, Bernardo L; Boyden, Edward S | Nature chemical biology. | 2018 Apr; | 29483642 | |
| Relationship Between Fibrosis Detected on Late Gadolinium-Enhanced Cardiac Magnetic Resonance and Re-Entrant Activity Assessed With Electrocardiographic Imaging in Human Persistent Atrial Fibrillation. | Cochet, Hubert; Dubois, Rémi; Yamashita, Seigo; Al Jefairi, Nora; Berte, Benjamin; Sellal, Jean-Marc; Hooks, Darren; Frontera, Antonio; Amraoui, Sana; Zemoura, Adlane; Denis, Arnaud; Derval, Nicolas; Sacher, Frederic; Corneloup, Olivier; Latrabe, Valérie; Clément-Guinaudeau, Stéphanie; Relan, Jatin; Zahid, Sohail; Boyle, Patrick M; Trayanova, Natalia A; Bernus, Olivier; Montaudon, Michel; Laurent, François; Hocini, Mélèze; Haïssaguerre, Michel; Jaïs, Pierre | JACC. Clinical electrophysiology. | 2018 Jan; | 29479568 | |
| Changes in Ugandan Climate Rainfall at the Village and Forest Level. | Ssentongo, Paddy; Muwanguzi, Abraham J B; Eden, Uri; Sauer, Timothy; Bwanga, George; Kateregga, Geoffrey; Aribo, Lawrence; Ojara, Moses; Mugerwa, Wilberforce Kisamba; Schiff, Steven J | Scientific reports. | 2018 Feb 23; | 29476058 | |
| Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia. | Datta, Dibyadeep; Arnsten, Amy F T | ACS chemical neuroscience. | 2018 Mar 01; | 29470055 | |
| Modifications and functional genomics of human transfer RNA. | Pan, Tao | Cell research. | 2018 Apr; | 29463900 | |
| OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes. | Beliveau, Brian J; Kishi, Jocelyn Y; Nir, Guy; Sasaki, Hiroshi M; Saka, Sinem K; Nguyen, Son C; Wu, Chao-Ting; Yin, Peng | Proceedings of the National Academy of Sciences of the United States of America. | 2018 Mar 06; | 29463736 | |
| QFMatch: multidimensional flow and mass cytometry samples alignment. | Orlova, Darya Y; Meehan, Stephen; Parks, David; Moore, Wayne A; Meehan, Connor; Zhao, Qian; Ghosn, Eliver E B; Herzenberg, Leonore A; Walther, Guenther | Scientific reports. | 2018 Feb 19; | 29459702 | |
| On the design of CRISPR-based single-cell molecular screens. | Hill, Andrew J; McFaline-Figueroa, José L; Starita, Lea M; Gasperini, Molly J; Matreyek, Kenneth A; Packer, Jonathan; Jackson, Dana; Shendure, Jay; Trapnell, Cole | Nature methods. | 2018 Apr; | 29457792 | |
| Inflammation NODs to Antagonists of RIP2-XIAP Interaction. | Xia, Shiyu; Fu, Tian-Min; Wu, Hao | Molecular cell. | 2018 02 15; | 29452633 | |
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| 3D NIR-II Molecular Imaging Distinguishes Targeted Organs with High-Performance NIR-II Bioconjugates. | Zhu, Shoujun; Herraiz, Sonia; Yue, Jingying; Zhang, Mingxi; Wan, Hao; Yang, Qinglai; Ma, Zhuoran; Wang, Yan; He, Jiahuan; Antaris, Alexander L; Zhong, Yeteng; Diao, Shuo; Feng, Yi; Zhou, Ying; Yu, Kuai; Hong, Guosong; Liang, Yongye; Hsueh, Aaron J; Dai, Hongjie | Advanced materials (Deerfield Beach, Fla.). | 2018 Mar; | 29446156 | |
| A spatial gradient of bacterial diversity in the human oral cavity shaped by salivary flow. | Proctor, Diana M; Fukuyama, Julia A; Loomer, Peter M; Armitage, Gary C; Lee, Stacey A; Davis, Nicole M; Ryder, Mark I; Holmes, Susan P; Relman, David A | Nature communications. | ; | 29445174 | |
| Label-free cell nuclear imaging by Grüneisen relaxation photoacoustic microscopy. | Liu, Xiaowei; Wong, Terence T W; Shi, Junhui; Ma, Jun; Yang, Qing; Wang, Lihong V | Optics letters. | 2018 Feb 15; | 29444034 | |
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| Targeted antigen delivery by an anti-class II MHC VHH elicits focused ?MUC1(Tn) immunity. | Fang, Tao; Van Elssen, Catharina H M J; Duarte, Joao N; Guzman, Jonathan S; Chahal, Jasdave S; Ling, Jingjing; Ploegh, Hidde L | Chemical science. | 2017 Aug 01; | 28970938 | |
| Sensitivity of reentrant driver localization to electrophysiological parameter variability in image-based computational models of persistent atrial fibrillation sustained by a fibrotic substrate. | Deng, Dongdong; Murphy, Michael J; Hakim, Joe B; Franceschi, William H; Zahid, Sohail; Pashakhanloo, Farhad; Trayanova, Natalia A; Boyle, Patrick M | Chaos (Woodbury, N.Y.). | 2017 Sep; | 28964164 | |
| Boosting the down-shifting luminescence of rare-earth nanocrystals for biological imaging beyond 1500?nm. | Zhong, Yeteng; Ma, Zhuoran; Zhu, Shoujun; Yue, Jingying; Zhang, Mingxi; Antaris, Alexander L; Yuan, Jie; Cui, Ran; Wan, Hao; Zhou, Ying; Wang, Weizhi; Huang, Ngan F; Luo, Jian; Hu, Zhiyuan; Dai, Hongjie | Nature communications. | 2017 09 29; | 28963467 | |
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| Closed-Loop Real-Time Imaging Enables Fully Automated Cell-Targeted Patch-Clamp Neural Recording In Vivo. | Suk, Ho-Jun; van Welie, Ingrid; Kodandaramaiah, Suhasa B; Allen, Brian; Forest, Craig R; Boyden, Edward S | Neuron. | 2017 Sep 27; | 28957673 | |
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| Enhanced Nociception in Angelman Syndrome Model Mice. | McCoy, Eric S; Taylor-Blake, Bonnie; Aita, Megumi; Simon, Jeremy M; Philpot, Benjamin D; Zylka, Mark J | The Journal of neuroscience : the official journal of the Society for Neuroscience. | 2017 Oct 18; | 28931574 | |
| Estimation and Inference for the Mediation Proportion. | Nevo, Daniel; Liao, Xiaomei; Spiegelman, Donna | The international journal of biostatistics. | 2017 09 20; | 28930628 | |
| In Situ Super-Resolution Imaging of Genomic DNA with OligoSTORM and OligoDNA-PAINT. | Beliveau, Brian J; Boettiger, Alistair N; Nir, Guy; Bintu, Bogdan; Yin, Peng; Zhuang, Xiaowei; Wu, C-Ting | Methods in molecular biology (Clifton, N.J.). | ; | 28924672 | |
| Metabolic crosstalk regulates Porphyromonas gingivalis colonization and virulence during oral polymicrobial infection. | Kuboniwa, Masae; Houser, John R; Hendrickson, Erik L; Wang, Qian; Alghamdi, Samar A; Sakanaka, Akito; Miller, Daniel P; Hutcherson, Justin A; Wang, Tiansong; Beck, David A C; Whiteley, Marvin; Amano, Atsuo; Wang, Huizhi; Marcotte, Edward M; Hackett, Murray; Lamont, Richard J | Nature microbiology. | 2017 Nov; | 28924191 | |
| Tissue Engineering of 3D Organotypic Microtissues by Acoustic Assembly. | Zhu, Yuqing; Serpooshan, Vahid; Wu, Sean; Demirci, Utkan; Chen, Pu; Güven, Sinan | Methods in molecular biology (Clifton, N.J.). | ; | 28921421 | |
| mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein. | Nofal, Michel; Zhang, Kevin; Han, Seunghun; Rabinowitz, Joshua D | Molecular cell. | 2017 Sep 21; | 28918901 | |
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| Selenocysteine tRNA[Ser]Sec, the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing. | Carlson, Bradley A; Lee, Byeong Jae; Tsuji, Petra A; Copeland, Paul R; Schweizer, Ulrich; Gladyshev, Vadim N; Hatfield, Dolph L | Methods in molecular biology (Clifton, N.J.). | 2018; | 28917036 | |
| Chemical Basis for Deuterium Labeling of Fat and NADPH. | Zhang, Zhaoyue; Chen, Li; Liu, Ling; Su, Xiaoyang; Rabinowitz, Joshua D | Journal of the American Chemical Society. | 2017 Oct 18; | 28911221 | |
| Distinct roles for motor neuron autophagy early and late in the SOD1G93A mouse model of ALS. | Rudnick, Noam D; Griffey, Christopher J; Guarnieri, Paolo; Gerbino, Valeria; Wang, Xueyong; Piersaint, Jason A; Tapia, Juan Carlos; Rich, Mark M; Maniatis, Tom | Proceedings of the National Academy of Sciences of the United States of America. | 2017 Sep 26; | 28904095 | |
| SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. | Ohashi, Masao; Liu, Fang; Hai, Yang; Chen, Mengbin; Tang, Man-Cheng; Yang, Zhongyue; Sato, Michio; Watanabe, Kenji; Houk, K N; Tang, Yi | Nature. | 2017 Sep 28; | 28902839 | |
| Machine Learning Analysis Identifies Drosophila Grunge/Atrophin as an Important Learning and Memory Gene Required for Memory Retention and Social Learning. | Kacsoh, Balint Z; Greene, Casey S; Bosco, Giovanni | G3 (Bethesda, Md.). | 2017 Nov 06; | 28889104 | |
| Variant Interpretation: Functional Assays to the Rescue. | Starita, Lea M; Ahituv, Nadav; Dunham, Maitreya J; Kitzman, Jacob O; Roth, Frederick P; Seelig, Georg; Shendure, Jay; Fowler, Douglas M | American journal of human genetics. | 2017 Sep 07; | 28886340 | |
| CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs. | Wu, Jun; Vilarino, Marcela; Suzuki, Keiichiro; Okamura, Daiji; Bogliotti, Yanina Soledad; Park, Insung; Rowe, Joan; McNabb, Bret; Ross, Pablo Juan; Belmonte, Juan Carlos Izpisua | Scientific reports. | 2017 Sep 05; | 28874671 | |
| Localized CD47 blockade enhances immunotherapy for murine melanoma. | Ingram, Jessica R; Blomberg, Olga S; Sockolosky, Jonathan T; Ali, Lestat; Schmidt, Florian I; Pishesha, Novalia; Espinosa, Camilo; Dougan, Stephanie K; Garcia, K Christopher; Ploegh, Hidde L; Dougan, Michael | Proceedings of the National Academy of Sciences of the United States of America. | 2017 Sep 19; | 28874561 | |
| PhenoGraph and viSNE facilitate the identification of abnormal T-cell populations in routine clinical flow cytometric data. | DiGiuseppe, Joseph A; Cardinali, Jolene L; Rezuke, William N; Pe'er, Dana | Cytometry. Part B, Clinical cytometry. | 2017 Sep 02; | 28865188 | |
| Closed-Loop Real-Time Imaging Enables Fully Automated Cell-Targeted Patch-Clamp Neural Recording In Vivo. | Suk, Ho-Jun; van Welie, Ingrid; Kodandaramaiah, Suhasa B; Allen, Brian; Forest, Craig R; Boyden, Edward S | Neuron. | 2017 Aug 30; | 28858614 | |
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| What is changing when: Decoding visual information in movies from human intracranial recordings. | Isik, Leyla; Singer, Jedediah; Madsen, Joseph R; Kanwisher, Nancy; Kreiman, Gabriel | NeuroImage. | 2017 Aug 18; | 28823828 | |
| Comprehensive single-cell transcriptional profiling of a multicellular organism. | Cao, Junyue; Packer, Jonathan S; Ramani, Vijay; Cusanovich, Darren A; Huynh, Chau; Daza, Riza; Qiu, Xiaojie; Lee, Choli; Furlan, Scott N; Steemers, Frank J; Adey, Andrew; Waterston, Robert H; Trapnell, Cole; Shendure, Jay | Science (New York, N.Y.). | 2017 08 18; | 28818938 | |
| Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression. | Zhu, Yu; Herndon, John M; Sojka, Dorothy K; Kim, Ki-Wook; Knolhoff, Brett L; Zuo, Chong; Cullinan, Darren R; Luo, Jingqin; Bearden, Audrey R; Lavine, Kory J; Yokoyama, Wayne M; Hawkins, William G; Fields, Ryan C; Randolph, Gwendalyn J; DeNardo, David G | Immunity. | 2017 08 15; | 28813661 | |
| Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria. | Chen, Jianwei; Jiang, Xiqian; Zhang, Chengwei; MacKenzie, Kevin R; Stossi, Fabio; Palzkill, Timothy; Wang, Meng C; Wang, Jin | ACS sensors. | 2017 Sep 22; | 28809477 | |
| AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. | Chow, Ryan D; Guzman, Christopher D; Wang, Guangchuan; Schmidt, Florian; Youngblood, Mark W; Ye, Lupeng; Errami, Youssef; Dong, Matthew B; Martinez, Michael A; Zhang, Sensen; Renauer, Paul; Bilguvar, Kaya; Gunel, Murat; Sharp, Phillip A; Zhang, Feng; Platt, Randall J; Chen, Sidi | Nature neuroscience. | 2017 Oct; | 28805815 | |
| Sonofragmentation of Ultrathin 1D Nanomaterials. | Gao, Ruixuan; Gupta, Ishan; Boyden, Edward S | Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems. | 2017 Jan; | 28804214 | |
| Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade. | Wei, Spencer C; Levine, Jacob H; Cogdill, Alexandria P; Zhao, Yang; Anang, Nana-Ama A S; Andrews, Miles C; Sharma, Padmanee; Wang, Jing; Wargo, Jennifer A; Pe'er, Dana; Allison, James P | Cell. | 2017 Sep 07; | 28803728 | |
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| A molecular signature for anastasis, recovery from the brink of apoptotic cell death. | Sun, Gongping; Guzman, Elmer; Balasanyan, Varuzhan; Conner, Christopher M; Wong, Kirsten; Zhou, Hongjun Robin; Kosik, Kenneth S; Montell, Denise J | The Journal of cell biology. | 2017 Oct 02; | 28768686 | |
| Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake. | Díaz-García, Carlos Manlio; Mongeon, Rebecca; Lahmann, Carolina; Koveal, Dorothy; Zucker, Hannah; Yellen, Gary | Cell metabolism. | 2017 Aug 01; | 28768175 | |
| Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells. | Alumasa, John N; Manzanillo, Paolo S; Peterson, Nicholas D; Lundrigan, Tricia; Baughn, Anthony D; Cox, Jeffery S; Keiler, Kenneth C | ACS infectious diseases. | 2017 Sep 08; | 28762275 | |
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| Critical Comparison of FRET-Sensor Functionality in the Cytosol and Endoplasmic Reticulum and Implications for Quantification of Ions. | Carter, Kyle P; Carpenter, Margaret C; Fiedler, Brett; Jimenez, Ralph; Palmer, Amy E | Analytical chemistry. | 2017 Sep 05; | 28758723 | |
| AID Recognizes Structured DNA for Class Switch Recombination. | Qiao, Qi; Wang, Li; Meng, Fei-Long; Hwang, Joyce K; Alt, Frederick W; Wu, Hao | Molecular cell. | 2017 Aug 03; | 28757211 | |
| Expression and Purification of Active Recombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli. | Krishnan, Beena; Hedstrom, Lizbeth; Hebert, Daniel N; Gierasch, Lila M; Gershenson, Anne | Methods in molecular biology (Clifton, N.J.). | 2017; | 28752459 | |
| Targeted DNA methylation in human cells using engineered dCas9-methyltransferases. | Xiong, Tina; Meister, Glenna E; Workman, Rachael E; Kato, Nathaniel C; Spellberg, Michael J; Turker, Fulya; Timp, Winston; Ostermeier, Marc; Novina, Carl D | Scientific reports. | 2017 Jul 27; | 28751638 | |
| ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells. | Ou, Horng D; Phan, Sébastien; Deerinck, Thomas J; Thor, Andrea; Ellisman, Mark H; O'Shea, Clodagh C | Science (New York, N.Y.). | 2017 07 28; | 28751582 | |
| Multiview Hilbert transformation in full-ring transducer array-based photoacoustic computed tomography. | Li, Lei; Zhu, Liren; Shen, Yuecheng; Wang, Lihong V | Journal of biomedical optics. | 2017 07 01; | 28745385 | |
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| In Vivo Rescue of the Hematopoietic Niche By Pluripotent Stem Cell Complementation of Defective Osteoblast Compartments. | Chubb, Rhiannon; Oh, James; Riley, Alyssa K; Kimura, Takaharu; Wu, Sean M; Wu, Joy Y | Stem cells (Dayton, Ohio). | 2017 Oct; | 28741855 | |
| Identification of a hybrid myocardial zone in the mammalian heart after birth. | Tian, Xueying; Li, Yan; He, Lingjuan; Zhang, Hui; Huang, Xiuzhen; Liu, Qiaozhen; Pu, Wenjuan; Zhang, Libo; Li, Yi; Zhao, Huan; Wang, Zhifu; Zhu, Jianhong; Nie, Yu; Hu, Shengshou; Sedmera, David; Zhong, Tao P; Yu, Ying; Zhang, Li; Yan, Yan; Qiao, Zengyong; | Nature communications. | ; | 28729659 | |
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| Nanoscale imaging of clinical specimens using pathology-optimized expansion microscopy. | Zhao, Yongxin; Bucur, Octavian; Irshad, Humayun; Chen, Fei; Weins, Astrid; Stancu, Andreea L; Oh, Eun-Young; DiStasio, Marcello; Torous, Vanda; Glass, Benjamin; Stillman, Isaac E; Schnitt, Stuart J; Beck, Andrew H; Boyden, Edward S | Nature biotechnology. | 2017 Aug; | 28714966 | |
| Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. | Chai, Hua; Diaz-Castro, Blanca; Shigetomi, Eiji; Monte, Emma; Octeau, J Christopher; Yu, Xinzhu; Cohn, Whitaker; Rajendran, Pradeep S; Vondriska, Thomas M; Whitelegge, Julian P; Coppola, Giovanni; Khakh, Baljit S | Neuron. | 2017 Jul 11; | 28712653 | |
| Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial. | Russell, Stephen; Bennett, Jean; Wellman, Jennifer A; Chung, Daniel C; Yu, Zi-Fan; Tillman, Amy; Wittes, Janet; Pappas, Julie; Elci, Okan; McCague, Sarah; Cross, Dominique; Marshall, Kathleen A; Walshire, Jean; Kehoe, Taylor L; Reichert, Hannah; Davis, Maria; Raffini, Leslie; George, Lindsey A; Hudson, F Parker; Dingfield, Laura; Zhu, Xiaosong; Haller, Julia A; Sohn, Elliott H; Mahajan, Vinit B; Pfeifer, Wanda; Weckmann, Michelle; Johnson, Chris; Gewaily, Dina; Drack, Arlene; Stone, Edwin; Wachtel, Katie; Simonelli, Francesca; Leroy, Bart P; Wright, J Fraser; High, Katherine A; Maguire, Albert M | Lancet (London, England). | 2017 Aug 26; | 28712537 | |
| CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions. | Gasperini, Molly; Findlay, Gregory M; McKenna, Aaron; Milbank, Jennifer H; Lee, Choli; Zhang, Melissa D; Cusanovich, Darren A; Shendure, Jay | American journal of human genetics. | 2017 Aug 03; | 28712454 | |
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| Novel mobility test to assess functional vision in patients with inherited retinal dystrophies. | Chung, Daniel C; McCague, Sarah; Yu, Zi-Fan; Thill, Satha; DiStefano-Pappas, Julie; Bennett, Jean; Cross, Dominique; Marshall, Kathleen; Wellman, Jennifer; High, Katherine A | Clinical & experimental ophthalmology. | 2017 Jul 11; | 28697537 | |
| Thermoneutrality but not UCP1 Deficiency Suppresses Monocyte Mobilization into Blood. | Williams, Jesse W; Elvington, Andrew F; Ivanov, Stoyan; Kessler, Skyler; Luehmann, Hannah; Baba, Osamu; Saunders, Brian T; Kim, Ki-Wook; Johnson, Michael W; Craft, Clarissa S; Choi, Jae-Hoon; Sorci-Thomas, Mary G; Zinselmeyer, Bernd H; Brestoff, Jonathan | Circulation research. | 2017 Jul 10; | 28696252 | |
| Imaging-Based Simulations for Predicting Sudden Death and Guiding Ventricular Tachycardia Ablation. | Trayanova, Natalia A; Pashakhanloo, Farhad; Wu, Katherine C; Halperin, Henry R | Circulation. Arrhythmia and electrophysiology. | 2017 Jul; | 28696219 | |
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| Metabolic labeling in middle-down proteomics allows for investigation of the dynamics of the histone code. | Sidoli, Simone; Lu, Congcong; Coradin, Mariel; Wang, Xiaoshi; Karch, Kelly R; Ruminowicz, Chrystian; Garcia, Benjamin A | Epigenetics & chromatin. | 2017 Jul 06; | 28683815 | |
| Reversible Product Release and Recapture by a Fungal Polyketide Synthase Using a Carnitine Acyltransferase Domain. | Hang, Leibniz; Tang, Man-Cheng; Harvey, Colin J B; Page, Claire G; Li, Jian; Hung, Yiu-Sun; Liu, Nicholas; Hillenmeyer, Maureen E; Tang, Yi | Angewandte Chemie (International ed. in English). | 2017 Aug 01; | 28679030 | |
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| Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells. | Rashidian, Mohammad; Ingram, Jessica R; Dougan, Michael; Dongre, Anushka; Whang, Katherine A; LeGall, Camille; Cragnolini, Juan J; Bierie, Brian; Gostissa, Monica; Gorman, James; Grotenbreg, Gijsbert M; Bhan, Atul; Weinberg, Robert A; Ploegh, Hidde L | The Journal of experimental medicine. | 2017 Aug 07; | 28666979 | |
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| A Prospective Study of Age-dependent Changes in Propofol-induced Electroencephalogram Oscillations in Children. | Lee, Johanna M; Akeju, Oluwaseun; Terzakis, Kristina; Pavone, Kara J; Deng, Hao; Houle, Timothy T; Firth, Paul G; Shank, Erik S; Brown, Emery N; Purdon, Patrick L | Anesthesiology. | 2017 08; | 28657957 | |
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| CIDE domains form functionally important higher-order assemblies for DNA fragmentation. | Choi, Jae Young; Qiao, Qi; Hong, Se-Hoon; Kim, Chang Min; Jeong, Jae-Hee; Kim, Yeon-Gil; Jung, Yong-Keun; Wu, Hao; Park, Hyun Ho | Proceedings of the National Academy of Sciences of the United States of America. | 2017 Jul 11; | 28652364 | |
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| Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1. | Chen, Jonathan L; VanEtten, Damian M; Fountain, Matthew A; Yildirim, Ilyas; Disney, Matthew D | Biochemistry. | 2017 07 11; | 28617590 | |
| Identification and Heterologous Production of a Benzoyl-Primed Tricarboxylic Acid Polyketide Intermediate from the Zaragozic Acid A Biosynthetic Pathway. | Liu, Nicholas; Hung, Yiu-Sun; Gao, Shu-Shan; Hang, Leibniz; Zou, Yi; Chooi, Yit-Heng; Tang, Yi | Organic letters. | 2017 Jul 07; | 28605916 | |
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| Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation. | Chow, Brian Wai; Gu, Chenghua | Neuron. | 2017 Mar 22; | 28334606 | |
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| Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults. | Pollack, Rena M; Barzilai, Nir; Anghel, Valentin; Kulkarni, Ameya S; Golden, Aaron; O'Broin, Pilib; Sinclair, David A; Bonkowski, Michael S; Coleville, Alexander J; Powell, Danielle; Kim, Sharon; Moaddel, Ruin; Stein, Daniel; Zhang, Kehao; Hawkins, Meredi | The journals of gerontology. Series A, Biological sciences and medical sciences. | 2017 Nov 09; | 28329397 | |
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| Lymphoid Aggregates Remodel Lymphatic Collecting Vessels that Serve Mesenteric Lymph Nodes in Crohn Disease. | Randolph, Gwendalyn J; Bala, Shashi; Rahier, Jean-François; Johnson, Michael W; Wang, Peter L; Nalbantoglu, ILKe; Dubuquoy, Laurent; Chau, Amélie; Pariente, Benjamin; Kartheuser, Alex; Zinselmeyer, Bernd H; Colombel, Jean-Frederic | The American journal of pathology. | 2016 Dec; | 27746181 | |
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| Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10. | Yang, Wang-Yong; Gao, Rui; Southern, Mark; Sarkar, Partha S; Disney, Matthew D | Nature communications. | 2016 Jun 01; | 27248057 | |
| The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and Proliferation and Survival of Cells. | Duan, Yajian; Ma, Gaoen; Huang, Xionggao; D'Amore, Patricia A; Zhang, Feng; Lei, Hetian | The Journal of biological chemistry. | 2016 07 29; | 27246850 | |
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| Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms. | Mabb, Angela M; Simon, Jeremy M; King, Ian F; Lee, Hyeong-Min; An, Lin-Kun; Philpot, Benjamin D; Zylka, Mark J | PloS one. | 2016; | 27231886 | |
| Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma. | Saha, Supriya K; Gordan, John D; Kleinstiver, Benjamin P; Vu, Phuong; Najem, Mortada S; Yeo, Jia-Chi; Shi, Lei; Kato, Yasutaka; Levin, Rebecca S; Webber, James T; Damon, Leah J; Egan, Regina K; Greninger, Patricia; McDermott, Ultan; Garnett, Mathew J; Jenkins, Roger L; Rieger-Christ, Kimberly M; Sullivan, Travis B; Hezel, Aram F; Liss, Andrew S; Mizukami, Yusuke; Goyal, Lipika; Ferrone, Cristina R; Zhu, Andrew X; Joung, J Keith; Shokat, Kevan M; Benes, Cyril H; Bardeesy, Nabeel | Cancer discovery. | 2016 07; | 27231123 | |
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| In vivo photoacoustic microscopy of human cuticle microvasculature with single-cell resolution. | Hsu, Hsun-Chia; Wang, Lidai; Wang, Lihong V | Journal of biomedical optics. | 2016 May 01; | 27207113 | |
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| Identification of the long, edited dsRNAome of LPS-stimulated immune cells. | Blango, Matthew G; Bass, Brenda L | Genome research. | 2016 Jun; | 27197207 | |
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| High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing. | Mikuni, Takayasu; Nishiyama, Jun; Sun, Ye; Kamasawa, Naomi; Yasuda, Ryohei | Cell. | 2016 Jun 16; | 27180908 | |
| GABAA circuit mechanisms are associated with ether anesthesia-induced unconsciousness. | Akeju, Oluwaseun; Hamilos, Allison E; Song, Andrew H; Pavone, Kara J; Purdon, Patrick L; Brown, Emery N | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. | 2016 Jun; | 27178867 | |
| Electroencephalogram signatures of ketamine anesthesia-induced unconsciousness. | Akeju, Oluwaseun; Song, Andrew H; Hamilos, Allison E; Pavone, Kara J; Flores, Francisco J; Brown, Emery N; Purdon, Patrick L | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. | 2016 Jun; | 27178861 | |
| The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons. | Lutas, Andrew; Lahmann, Carolina; Soumillon, Magali; Yellen, Gary | eLife. | 2016 May 13; | 27177420 | |
| The wiring diagram of a glomerular olfactory system. | Berck, Matthew E; Khandelwal, Avinash; Claus, Lindsey; Hernandez-Nunez, Luis; Si, Guangwei; Tabone, Christopher J; Li, Feng; Truman, James W; Fetter, Rick D; Louis, Matthieu; Samuel, Aravinthan Dt; Cardona, Albert | eLife. | 2016 May 13; | 27177418 | |
| Variability in paralimbic dopamine signaling correlates with subjective responses to d-amphetamine. | Smith, Christopher T; Dang, Linh C; Cowan, Ronald L; Kessler, Robert M; Zald, David H | Neuropharmacology. | 2016 Sep; | 27174408 | |
| Arrhythmia risk stratification of patients after myocardial infarction using personalized heart models. | Arevalo, Hermenegild J; Vadakkumpadan, Fijoy; Guallar, Eliseo; Jebb, Alexander; Malamas, Peter; Wu, Katherine C; Trayanova, Natalia A | Nature communications. | 2016 May 10; | 27164184 | |
| Cholinergic Signaling Controls Conditioned Fear Behaviors and Enhances Plasticity of Cortical-Amygdala Circuits. | Jiang, Li; Kundu, Srikanya; Lederman, James D; López-Hernández, Gretchen Y; Ballinger, Elizabeth C; Wang, Shaohua; Talmage, David A; Role, Lorna W | Neuron. | 2016 Jun 1; | 27161525 | |
| The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. | Toriyama, Michinori; Lee, Chanjae; Taylor, S Paige; Duran, Ivan; Cohn, Daniel H; Bruel, Ange-Line; Tabler, Jacqueline M; Drew, Kevin; Kelly, Marcus R; Kim, Sukyoung; Park, Tae Joo; Braun, Daniela A; Pierquin, Ghislaine; Biver, Armand; Wagner, Kerstin; Mal | Nature genetics. | 2016 Jun; | 27158779 | |
| Spiegelman Responds. | Spiegelman, Donna | American journal of public health. | 2016 Jun; | 27153027 | |
| Conflicting Selection Pressures Will Constrain Viral Escape from Interfering Particles: Principles for Designing Resistance-Proof Antivirals. | Rast, Luke I; Rouzine, Igor M; Rozhnova, Ganna; Bishop, Lisa; Weinberger, Ariel D; Weinberger, Leor S | PLoS computational biology. | 2016 May; | 27152856 | |
| Benchmarking Spike Rate Inference in Population Calcium Imaging. | Theis, Lucas; Berens, Philipp; Froudarakis, Emmanouil; Reimer, Jacob; Román Rosón, Miroslav; Baden, Tom; Euler, Thomas; Tolias, Andreas S; Bethge, Matthias | Neuron. | 2016 May 4; | 27151639 | |
| Exploiting Genetic Interference for Antiviral Therapy. | Tanner, Elizabeth J; Kirkegaard, Karla A; Weinberger, Leor S | PLoS genetics. | 2016 May; | 27149616 | |
| Mycobacterium Cytidylate Kinase Appears to Be an Undruggable Target. | Craig, Justin K; Risler, Jenni K; Loesch, Kimberly A; Dong, Wen; Baker, Dwight; Barrett, Lynn K; Subramanian, Sandhya; Samudrala, Ram; Van Voorhis, Wesley C | Journal of biomolecular screening. | 2016 Aug; | 27146385 | |
| Design Principles of Length Control of Cytoskeletal Structures. | Mohapatra, Lishibanya; Goode, Bruce L; Jelenkovic, Predrag; Phillips, Rob; Kondev, Jane | Annual review of biophysics. | 2016 Jul 05; | 27145876 | |
| A scaffold protein connects type IV pili with the Chp chemosensory system to mediate activation of virulence signaling in Pseudomonas aeruginosa. | Inclan, Yuki F; Persat, Alexandre; Greninger, Alexander; Von Dollen, John; Johnson, Jeffery; Krogan, Nevan; Gitai, Zemer; Engel, Joanne N | Molecular microbiology. | 2016 May 3; | 27145134 | |
| Functional connectivity dynamics during film viewing reveal common networks for different emotional experiences. | Raz, Gal; Touroutoglou, Alexandra; Wilson-Mendenhall, Christine; Gilam, Gadi; Lin, Tamar; Gonen, Tal; Jacob, Yael; Atzil, Shir; Admon, Roee; Bleich-Cohen, Maya; Maron-Katz, Adi; Hendler, Talma; Barrett, Lisa Feldman | Cognitive, affective & behavioral neuroscience. | 2016 08; | 27142636 | |
| An extrasynaptic GABAergic signal modulates a pattern of forward movement in Caenorhabditis elegans. | Shen, Yu; Wen, Quan; Liu, He; Zhong, Connie; Qin, Yuqi; Harris, Gareth; Kawano, Taizo; Wu, Min; Xu, Tianqi; Samuel, Aravinthan Dt; Zhang, Yun | eLife. | 2016 05 03; | 27138642 | |
| Wishbone identifies bifurcating developmental trajectories from single-cell data. | Setty, Manu; Tadmor, Michelle D; Reich-Zeliger, Shlomit; Angel, Omer; Salame, Tomer Meir; Kathail, Pooja; Choi, Kristy; Bendall, Sean; Friedman, Nir; Pe'er, Dana | Nature biotechnology. | 2016 Jun; | 27136076 | |
| A review of snapshot multidimensional optical imaging: measuring photon tags in parallel. | Gao, Liang; Wang, Lihong V | Physics reports. | 2016 Feb 29; | 27134340 | |
| Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies. | Ramanan, Vyas; Trehan, Kartik; Ong, Mei-Lyn; Luna, Joseph M; Hoffmann, Hans-Heinrich; Espiritu, Christine; Sheahan, Timothy P; Chandrasekar, Hamsika; Schwartz, Robert E; Christine, Kathleen S; Rice, Charles M; van Oudenaarden, Alexander; Bhatia, Sangeeta N | Virology. | 2016 07; | 27128351 | |
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| Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering. | Narayanan, Ganesh; Vernekar, Varadraj N; Kuyinu, Emmanuel L; Laurencin, Cato T | Advanced drug delivery reviews. | 2016 Apr 25; | 27125191 | |
| Programmable RNA-binding protein composed of repeats of a single modular unit. | Adamala, Katarzyna P; Martin-Alarcon, Daniel A; Boyden, Edward S | Proceedings of the National Academy of Sciences of the United States of America. | 2016 May 10; | 27118836 | |
| Layer-by-layer assembled fluorescent probes in the second near-infrared window for systemic delivery and detection of ovarian cancer. | Dang, Xiangnan; Gu, Li; Qi, Jifa; Correa, Santiago; Zhang, Geran; Belcher, Angela M; Hammond, Paula T | Proceedings of the National Academy of Sciences of the United States of America. | 2016 May 10; | 27114520 | |
| Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA. | Yamano, Takashi; Nishimasu, Hiroshi; Zetsche, Bernd; Hirano, Hisato; Slaymaker, Ian M; Li, Yinqing; Fedorova, Iana; Nakane, Takanori; Makarova, Kira S; Koonin, Eugene V; Ishitani, Ryuichiro; Zhang, Feng; Nureki, Osamu | Cell. | 2016 May 5; | 27114038 | |
| Feasibility of using patient-specific models and the ''minimum cut'' algorithm to predict optimal ablation targets for left atrial flutter. | Zahid, Sohail; Whyte, Kaitlyn N; Schwarz, Erica L; Blake 3rd, Robert C; Boyle, Patrick M; Chrispin, Jonathan; Prakosa, Adityo; Ipek, Esra G; Pashakhanloo, Farhad; Halperin, Henry R; Calkins, Hugh; Berger, Ronald D; Nazarian, Saman; Trayanova, Natalia A | Heart rhythm. | 2016 08; | 27108938 | |
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| Durable antitumor responses to CD47 blockade require adaptive immune stimulation. | Sockolosky, Jonathan T; Dougan, Michael; Ingram, Jessica R; Ho, Chia Chi M; Kauke, Monique J; Almo, Steven C; Ploegh, Hidde L; Garcia, K Christopher | Proceedings of the National Academy of Sciences of the United States of America. | 2016 May 10; | 27091975 | |
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| How Many Parameters Does It Take to Describe Disease Tolerance? | Louie, Alexander; Song, Kyung Han; Hotson, Alejandra; Thomas Tate, Ann; Schneider, David S | PLoS biology. | 2016 Apr; | 27088212 | |
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| Ketamine's Antidepressant Actions: Potential Mechanisms in the Primate Medial Prefrontal Circuits That Represent Aversive Experience. | Arnsten, Amy F T; Murray, John D; Seo, Hyojung; Lee, Daeyeol | Biological psychiatry. | 2016 May 01; | 27079495 | |
| The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome. | He, Baokun; Nohara, Kazunari; Park, Noheon; Park, Yong-Sung; Guillory, Bobby; Zhao, Zhaoyang; Garcia, Jose M; Koike, Nobuya; Lee, Cheng Chi; Takahashi, Joseph S; Yoo, Seung-Hee; Chen, Zheng | Cell metabolism. | 2016 Apr 12; | 27076076 | |
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| A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly. | Schmidt, Florian I; Lu, Alvin; Chen, Jeff W; Ruan, Jianbin; Tang, Catherine; Wu, Hao; Ploegh, Hidde L | The Journal of experimental medicine. | 2016 May 2; | 27069117 | |
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| Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism. | Lu, Alvin; Li, Yang; Schmidt, Florian I; Yin, Qian; Chen, Shuobing; Fu, Tian-Min; Tong, Alexander B; Ploegh, Hidde L; Mao, Youdong; Wu, Hao | Nature structural & molecular biology. | 2016 May; | 27043298 | |
| Sperm is epigenetically programmed to regulate gene transcription in embryos. | Teperek, Marta; Simeone, Angela; Gaggioli, Vincent; Miyamoto, Kei; Allen, George E; Erkek, Serap; Kwon, Taejoon; Marcotte, Edward M; Zegerman, Philip; Bradshaw, Charles R; Peters, Antoine H F M; Gurdon, John B; Jullien, Jerome | Genome research. | 2016 Mar 31; | 27034506 | |
| Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates. | Kaya, Alaattin; Ma, Siming; Wasko, Brian; Lee, Mitchell; Kaeberlein, Matt; Gladyshev, Vadim N | npj aging and mechanisms of disease. | 2015; | 27030810 | |
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| Astrocyte scar formation aids central nervous system axon regeneration. | Anderson, Mark A; Burda, Joshua E; Ren, Yilong; Ao, Yan; O'Shea, Timothy M; Kawaguchi, Riki; Coppola, Giovanni; Khakh, Baljit S; Deming, Timothy J; Sofroniew, Michael V | Nature. | 2016 Apr 14; | 27027288 | |
| Cooperative Subnetworks of Molecularly Similar Interneurons in Mouse Neocortex. | Karnani, Mahesh M; Jackson, Jesse; Ayzenshtat, Inbal; Tucciarone, Jason; Manoocheri, Kasra; Snider, William G; Yuste, Rafael | Neuron. | 2016 Apr 6; | 27021171 | |
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| Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice. | Jiang, Ruotian; Diaz-Castro, Blanca; Looger, Loren L; Khakh, Baljit S | The Journal of neuroscience : the official journal of the Society for Neuroscience. | 2016 Mar 23; | 27013675 | |
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| Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase. | Gao, Shu-Shan; Duan, Abing; Xu, Wei; Yu, Peiyuan; Hang, Leibniz; Houk, K N; Tang, Yi | Journal of the American Chemical Society. | 2016 Mar 22; | 26978228 | |
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| Calcium imaging of neural circuits with extended depth-of-field light-sheet microscopy. | Quirin, Sean; Vladimirov, Nikita; Yang, Chao-Tsung; Peterka, Darcy S; Yuste, Rafael; B Ahrens, Misha | Optics letters. | 2016 Mar 1; | 26974063 | |
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| Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia. | Arnsten, Amy F T; Girgis, Ragy R; Gray, David L; Mailman, Richard B | Biological psychiatry. | 2016 Jan 18; | 26946382 | |
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| Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. | Karch, Celeste M; Ezerskiy, Lubov A; Bertelsen, Sarah; Alzheimer?s Disease Genetics Consortium (ADGC); Goate, Alison M | PloS one. | 2016; | 26919393 | |
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| Early-branching gut fungi possess a large, comprehensive array of biomass-degrading enzymes. | Solomon, Kevin V; Haitjema, Charles H; Henske, John K; Gilmore, Sean P; Borges-Rivera, Diego; Lipzen, Anna; Brewer, Heather M; Purvine, Samuel O; Wright, Aaron T; Theodorou, Michael K; Grigoriev, Igor V; Regev, Aviv; Thompson, Dawn A; O'Malley, Michelle A | Science (New York, N.Y.). | 2016 Mar 11; | 26912365 | |
| Embedding a Panoramic Representation of Infrared Light in the Adult Rat Somatosensory Cortex through a Sensory Neuroprosthesis. | Hartmann, Konstantin; Thomson, Eric E; Zea, Ivan; Yun, Richy; Mullen, Peter; Canarick, Jay; Huh, Albert; Nicolelis, Miguel A L | The Journal of neuroscience : the official journal of the Society for Neuroscience. | 2016 Feb 24; | 26911689 | |
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| Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods. | Pelz, Nicholas F; Bian, Zhiguo; Zhao, Bin; Shaw, Subrata; Tarr, James C; Belmar, Johannes; Gregg, Claire; Camper, DeMarco V; Goodwin, Craig M; Arnold, Allison L; Sensintaffar, John L; Friberg, Anders; Rossanese, Olivia W; Lee, Taekyu; Olejniczak, Edward T; Fesik, Stephen W | Journal of medicinal chemistry. | 2016 Mar 10; | 26878343 | |
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| Design of a mobile, homogeneous, and efficient electromagnet with a large field of view for neonatal low-field MRI. | Lother, Steffen; Schiff, Steven J; Neuberger, Thomas; Jakob, Peter M; Fidler, Florian | Magma (New York, N.Y.). | 2016 Aug; | 26861046 | |
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| Structurally Defined ?MHC-II Nanobody-Drug Conjugates: A Therapeutic and Imaging System for B-Cell Lymphoma. | Fang, Tao; Duarte, Joao N; Ling, Jingjing; Li, Zeyang; Guzman, Jonathan S; Ploegh, Hidde L | Angewandte Chemie (International ed. in English). | 2016 Feb 12; | 26840214 | |
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| Neural Circuits Underlying Visually Evoked Escapes in Larval Zebrafish. | Dunn, Timothy W; Gebhardt, Christoph; Naumann, Eva A; Riegler, Clemens; Ahrens, Misha B; Engert, Florian; Del Bene, Filippo | Neuron. | 2016 Feb 3; | 613-28 | 26804997 |
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| Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein?A. | Patrone, James D; Pelz, Nicholas F; Bates, Brittney S; Souza-Fagundes, Elaine M; Vangamudi, Bhavatarini; Camper, Demarco V; Kuznetsov, Alexey G; Browning, Carrie F; Feldkamp, Michael D; Frank, Andreas O; Gilston, Benjamin A; Olejniczak, Edward T; Rossanese, Olivia W; Waterson, Alex G; Chazin, Walter J; Fesik, Stephen W | ChemMedChem. | 2016 Jan 8; | 26748787 | |
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| Myocardial Infarct Segmentation From Magnetic Resonance Images for Personalized Modeling of Cardiac Electrophysiology. | Ukwatta, Eranga; Arevalo, Hermenegild; Li, Kristina; Yuan, Jing; Qiu, Wu; Malamas, Peter; Wu, Katherine C; Trayanova, Natalia A; Vadakkumpadan, Fijoy | IEEE transactions on medical imaging. | 2016 Jun; | 26731693 | |
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| Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. | Sharma, Upasna; Conine, Colin C; Shea, Jeremy M; Boskovic, Ana; Derr, Alan G; Bing, Xin Y; Belleannee, Clemence; Kucukural, Alper; Serra, Ryan W; Sun, Fengyun; Song, Lina; Carone, Benjamin R; Ricci, Emiliano P; Li, Xin Z; Fauquier, Lucas; Moore, Melissa J | Science (New York, N.Y.). | 2016 Jan 22; | 26721685 | |
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| Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome. | Shea, Jeremy M; Serra, Ryan W; Carone, Benjamin R; Shulha, Hennady P; Kucukural, Alper; Ziller, Michael J; Vallaster, Markus P; Gu, Hongcang; Tapper, Andrew R; Gardner, Paul D; Meissner, Alexander; Garber, Manuel; Rando, Oliver J | Developmental cell. | 2015 Dec 21; | 26702833 | |
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| Image-based Reconstruction of 3D Myocardial Infarct Geometry for Patient Specific Applications. | Ukwatta, Eranga; Rajchl, Martin; White, James; Pashakhanloo, Farhad; Herzka, Daniel A; McVeigh, Elliot; Lardo, Albert C; Trayanova, Natalia; Vadakkumpadan, Fijoy | Proceedings of SPIE--the International Society for Optical Engineering. | 2015 Feb 21; | 26633913 | |
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| Understanding Programming of Fungal Iterative Polyketide Synthases: The Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase. | Cacho, Ralph A; Thuss, Justin; Xu, Wei; Sanichar, Randy; Gao, Zhizeng; Nguyen, Allison; Vederas, John C; Tang, Yi | Journal of the American Chemical Society. | 2015 Dec 23; | 26630357 | |
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| Composite Sequence-Structure Stability Models as Screening Tools for Identifying Vulnerable Targets for HIV Drug and Vaccine Development. | Manocheewa, Siriphan; Mittler, John E; Samudrala, Ram; Mullins, James I | Viruses. | 2015 Nov 04; | 26556362 | |
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| Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs. | Cochrane, Rachel V K; Gao, Zhizeng; Lambkin, Gareth R; Xu, Wei; Winter, Jaclyn M; Marcus, Sandra L; Tang, Yi; Vederas, John C | Chembiochem : a European journal of chemical biology. | 2015 Nov; | 26493380 | |
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| Graphene Oxide Nanosheets Modified with Single-Domain Antibodies for Rapid and Efficient Capture of Cells. | Chen, Guan-Yu; Li, Zeyang; Theile, Christopher S; Bardhan, Neelkanth M; Kumar, Priyank V; Duarte, Joao N; Maruyama, Takeshi; Rashidfarrokh, Ali; Belcher, Angela M; Ploegh, Hidde L | Chemistry (Weinheim an der Bergstrasse, Germany). | 2015 Nov 23; | 26472062 | |
| Seeing Through the Surface: Non-invasive Characterization of Biomaterial-Tissue Interactions Using Photoacoustic Microscopy. | Zhang, Yu Shrike; Wang, Lihong V; Xia, Younan | Annals of biomedical engineering. | 2015 Oct 15; | 26471785 | |
| Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast. | Tang, Man-Cheng; Lin, Hsiao-Ching; Li, Dehai; Zou, Yi; Li, Jian; Xu, Wei; Cacho, Ralph A; Hillenmeyer, Maureen E; Garg, Neil K; Tang, Yi | Journal of the American Chemical Society. | 2015 Nov 4; | 13724-7 | 26469304 |
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| Common variants in DRD2 are associated with sleep duration: the CARe consortium. | Cade, Brian E; Gottlieb, Daniel J; Lauderdale, Diane S; Bennett, David A; Buchman, Aron S; Buxbaum, Sarah G; De Jager, Philip L; Evans, Daniel S; Fülöp, Tibor; Gharib, Sina A; Johnson, W Craig; Kim, Hyun; Larkin, Emma K; Lee, Seung Ku; Lim, Andrew S; Punjabi, Naresh M; Shin, Chol; Stone, Katie L; Tranah, Gregory J; Weng, Jia; Yaffe, Kristine; Zee, Phyllis C; Patel, Sanjay R; Zhu, Xiaofeng; Redline, Susan; Saxena, Richa | Human molecular genetics. | 2016 Jan 1; | 167-79 | 26464489 |
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| Working memory capacity is associated with optimal adaptation of response bias to perceptual sensitivity in emotion perception. | Lynn, Spencer K; Ibagon, Camila; Bui, Eric; Palitz, Sophie A; Simon, Naomi M; Barrett, Lisa Feldman | Emotion (Washington, D.C.). | 2016 Mar; | 26461251 | |
| Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity. | Fonseca, Denise Morais da; Hand, Timothy W; Han, Seong-Ji; Gerner, Michael Y; Glatman Zaretsky, Arielle; Byrd, Allyson L; Harrison, Oliver J; Ortiz, Alexandra M; Quinones, Mariam; Trinchieri, Giorgio; Brenchley, Jason M; Brodsky, Igor E; Germain, Ronald N | Cell. | 2015 Oct 8; | 26451485 | |
| Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact. | Ehlen, J Christopher; Jones, Kelly A; Pinckney, Lennisha; Gray, Cloe L; Burette, Susan; Weinberg, Richard J; Evans, Jennifer A; Brager, Allison J; Zylka, Mark J; Paul, Ketema N; Philpot, Benjamin D; DeBruyne, Jason P | The Journal of neuroscience : the official journal of the Society for Neuroscience. | 2015 Oct 07; | 26446213 | |
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| A New MRI-Based Model of Heart Function with Coupled Hemodynamics and Application to Normal and Diseased Canine Left Ventricles. | Choi, Young Joon; Constantino, Jason; Vedula, Vijay; Trayanova, Natalia; Mittal, Rajat | Frontiers in bioengineering and biotechnology. | 2015; | 26442254 | |
| Lipid Profiles and Signals for Long Life. | Schroeder, Elizabeth A; Brunet, Anne | Trends in endocrinology and metabolism: TEM. | 2015 Nov; | 589-92 | 26439976 |
| Drosophila melanogaster Natural Variation Affects Growth Dynamics of Infecting Listeria monocytogenes. | Hotson, Alejandra Guzmán; Schneider, David S | G3 (Bethesda, Md.). | 2015 Dec; | 26438294 | |
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| Cardioprotective Actions of TGF?RI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors. | Ho, Yu-Sian; Tsai, Wan-Hsuan; Lin, Fen-Chiung; Huang, Wei-Pang; Lin, Lung-Chun; Wu, Sean M; Liu, Yu-Ru; Chen, Wen-Pin | Stem cells (Dayton, Ohio). | 2015 Sep 29; | 26418219 | |
| Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1?: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease. | Ladell, Kristin; Hazenberg, Mette D; Fitch, Mark; Emson, Claire; McEvoy-Hein Asgarian, Bridget K; Mold, Jeff E; Miller, Corey; Busch, Robert; Price, David A; Hellerstein, Marc K; McCune, Joseph M | Journal of immunology (Baltimore, Md. : 1950). | 2015 Nov 1; | 4096-105 | 26416271 |
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| Efficient Biosynthesis of Fungal Polyketides Containing the Dioxabicyclo-octane Ring System. | Mao, Xu-Ming; Zhan, Zha-Jun; Grayson, Matthew N; Tang, Man-Cheng; Xu, Wei; Li, Yong-Quan; Yin, Wen-Bing; Lin, Hsiao-Ching; Chooi, Yit-Heng; Houk, K N; Tang, Yi | Journal of the American Chemical Society. | 2015 Sep 23; | 11904-7 | 26340065 |
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| Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. | Winter, Jaclyn M; Cascio, Duilio; Dietrich, David; Sato, Michio; Watanabe, Kenji; Sawaya, Michael R; Vederas, John C; Tang, Yi | Journal of the American Chemical Society. | 2015 Aug 12; | 9885-93 | 26172141 |
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| Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity. | Kachroo, Aashiq H; Laurent, Jon M; Yellman, Christopher M; Meyer, Austin G; Wilke, Claus O; Marcotte, Edward M | Science (New York, N.Y.). | 2015 May 22; | 921-5 | 25999509 |
| Does Autism Diagnosis Age or Symptom Severity Differ Among Children According to Whether Assisted Reproductive Technology was Used to Achieve Pregnancy? | Schieve, Laura A; Fountain, Christine; Boulet, Sheree L; Yeargin-Allsopp, Marshalyn; Kissin, Dmitry M; Jamieson, Denise J; Rice, Catherine; Bearman, Peter | Journal of autism and developmental disorders. | 2015 Sep; | 2991-3003 | 25997596 |
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| Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss. | Sturzu, Anthony C; Rajarajan, Kuppusamy; Passer, Derek; Plonowska, Karolina; Riley, Alyssa; Tan, Timothy C; Sharma, Arun; Xu, Adele F; Engels, Marc C; Feistritzer, Rebecca; Li, Guang; Selig, Martin K; Geissler, Richard; Robertson, Keston D; Scherrer-Crosb | Circulation. | 2015 Jul 14; | 109-21 | 25995316 |
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| Cells change their sensitivity to an EGF morphogen gradient to control EGF-induced gene expression. | van Zon, Jeroen Sebastiaan; Kienle, Simone; Huelsz-Prince, Guizela; Barkoulas, Michalis; van Oudenaarden, Alexander | Nature communications. | 2015; | 7053 | 25958991 |
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| Somatic mutation as a mechanism of Wnt/*-catenin pathway activation in CLL. | Wang, Lili; Shalek, Alex K; Lawrence, Mike; Ding, Ruihua; Gaublomme, Jellert T; Pochet, Nathalie; Stojanov, Petar; Sougnez, Carrie; Shukla, Sachet A; Stevenson, Kristen E; Zhang, Wandi; Wong, Jessica; Sievers, Quinlan L; MacDonald, Bryan T; Vartanov, Alexander R; Goldstein, Natalie R; Neuberg, Donna; He, Xi; Lander, Eric; Hacohen, Nir; Regev, Aviv; Getz, Gad; Brown, Jennifer R; Park, Hongkun; Wu, Catherine J | Blood. | 2014 Aug 14; | 1089-98 | 24778153 |
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| A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging. | Chen, Yao; Saulnier, Jessica L; Yellen, Gary; Sabatini, Bernardo L | Frontiers in pharmacology | 2014 | 56 | 24765076 |
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| Population code in mouse V1 facilitates readout of natural scenes through increased sparseness. | Froudarakis, Emmanouil; Berens, Philipp; Ecker, Alexander S; Cotton, R James; Sinz, Fabian H; Yatsenko, Dimitri; Saggau, Peter; Bethge, Matthias; Tolias, Andreas S | Nature neuroscience | 2014 Jun | 851-7 | 24747577 |
| Small-molecule RORýýt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. | Xiao, Sheng; Yosef, Nir; Yang, Jianfei; Wang, Yonghui; Zhou, Ling; Zhu, Chen; Wu, Chuan; Baloglu, Erkan; Schmidt, Darby; Ramesh, Radha; Lobera, Mercedes; Sundrud, Mark S; Tsai, Pei-Yun; Xiang, Zhijun; Wang, Jinsong; Xu, Yan; Lin, Xichen; Kretschmer, Karst | Immunity | 2014 Apr 17 | 477-89 | 24745332 |
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| Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. | Haustein, Martin D; Kracun, Sebastian; Lu, Xiao-Hong; Shih, Tiffany; Jackson-Weaver, Olan; Tong, Xiaoping; Xu, Ji; Yang, X William; O'Dell, Thomas J; Marvin, Jonathan S; Ellisman, Mark H; Bushong, Eric A; Looger, Loren L; Khakh, Baljit S | Neuron. | 2014 Apr 16; | 413-29 | 24742463 |
| Representing sex in the brain, one module at a time. | Yang, Cindy F; Shah, Nirao M | Neuron | 2014 Apr 16 | 261-78 | 24742456 |
| Protein-to-mRNA Ratios Are Conserved between Pseudomonas aeruginosa Strains. | Kwon, Taejoon; Huse, Holly K; Vogel, Christine; Whiteley, Marvin; Marcotte, Edward M | Journal of proteome research | 2014 Apr 17 | NULL | 24742327 |
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| Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media. | Yao, Junjie; Gilson, Rebecca C; Maslov, Konstantin I; Wang, Lidai; Wang, Lihong V | Journal of biomedical optics | 2014 Apr | 46007 | 24718385 |
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| cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex. | Carlyle, Becky C; Nairn, Angus C; Wang, Min; Yang, Yang; Jin, Lu E; Simen, Arthur A; Ramos, Brian P; Bordner, Kelly A; Craft, George E; Davies, Peter; Pletikos, Mihovil; ?estan, Nenad; Arnsten, Amy F T; Paspalas, Constantinos D | Proceedings of the National Academy of Sciences of the United States of America. | 2014 Apr 1; | 5036-41 | 24707050 |
| Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1. | Kiskinis, Evangelos; Sandoe, Jackson; Williams, Luis A; Boulting, Gabriella L; Moccia, Rob; Wainger, Brian J; Han, Steve; Peng, Theodore; Thams, Sebastian; Mikkilineni, Shravani; Mellin, Cassidy; Merkle, Florian T; Davis-Dusenbery, Brandi N; Ziller, Micha | Cell stem cell | 2014 Jun 5 | 781-95 | 24704492 |
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| State dependence of noise correlations in macaque primary visual cortex. | Ecker, Alexander S; Berens, Philipp; Cotton, R James; Subramaniyan, Manivannan; Denfield, George H; Cadwell, Cathryn R; Smirnakis, Stelios M; Bethge, Matthias; Tolias, Andreas S | Neuron | 2014 Apr 2 | 235-48 | 24698278 |
| Chaperones and cardiac misfolding protein diseases. | Christians, Elisabeth S; Mustafi, Soumyajit B; Benjamin, Ivor J | Current protein & peptide science | 2014 May | 189-204 | 24694370 |
| Urogenital photoacoustic endoscope. | Li, Chiye; Yang, Joon-Mo; Chen, Ruimin; Yeh, Cheng-Hung; Zhu, Liren; Maslov, Konstantin; Zhou, Qifa; Kirk Shung, K; Wang, Lihong V | Optics letters | 2014 Mar 15 | 1473-6 | 24690816 |
| Improved in vitro efficacy of gold nanoconstructs by increased loading of G-quadruplex aptamer. | Dam, Duncan Hieu M; Lee, Raymond C; Odom, Teri W | Nano letters | 2014 May 14 | 2843-8 | 24689438 |
| Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice. | Tong, Xiaoping; Ao, Yan; Faas, Guido C; Nwaobi, Sinifunanya E; Xu, Ji; Haustein, Martin D; Anderson, Mark A; Mody, Istvan; Olsen, Michelle L; Sofroniew, Michael V; Khakh, Baljit S | Nature neuroscience. | 2014 May; | 694-703 | 24686787 |
| Fully motorized optical-resolution photoacoustic microscopy. | Li, Lei; Yeh, Chenghung; Hu, Song; Wang, Lidai; Soetikno, Brian T; Chen, Ruimin; Zhou, Qifa; Shung, K Kirk; Maslov, Konstantin I; Wang, Lihong V | Optics letters | 2014 Apr 1 | 2117-20 | 24686689 |
| Comparison of the theoretical and real-world evolutionary potential of a genetic circuit. | Razo-Mejia, M; Boedicker, J Q; Jones, D; Deluna, A; Kinney, J B; Phillips, R | Physical biology | 2014 Apr | 26005 | 24685590 |
| Proteomic identification of monoclonal antibodies from serum. | Boutz, Daniel R; Horton, Andrew P; Wine, Yariv; Lavinder, Jason J; Georgiou, George; Marcotte, Edward M | Analytical chemistry | 2014 May 20 | 4758-66 | 24684310 |
| Transcriptional profiling of cells sorted by RNA abundance. | Klemm, Sandy; Semrau, Stefan; Wiebrands, Kay; Mooijman, Dylan; Faddah, Dina A; Jaenisch, Rudolf; van Oudenaarden, Alexander | Nature methods | 2014 May | 549-51 | 24681693 |
| Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. | Mauer, Jan; Chaurasia, Bhagirath; Goldau, Julia; Vogt, Merly C; Ruud, Johan; Nguyen, Khoa D; Theurich, Sebastian; Hausen, A Christine; Schmitz, Joel; Bronneke, Hella S; Estevez, Emma; Allen, Tamara L; Mesaros, Andrea; Partridge, Linda; Febbraio, Mark A; C | Nature immunology | 2014 May | 423-30 | 24681566 |
| Minireview: Metabolism of female reproduction: regulatory mechanisms and clinical implications. | Seli, Emre; Babayev, Elnur; Collins, Stephen C; Nemeth, Gabor; Horvath, Tamas L | Molecular endocrinology (Baltimore, Md.) | 2014 Jun | 790-804 | 24678733 |
| Using SV119-Gold Nanocage Conjugates to Eradicate Cancer Stem Cells Through a Combination of Photothermal and Chemo Therapies. | Sun, Tianmeng; Wang, Yi; Wang, Yucai; Xu, Jinbin; Zhao, Xin; Vangveravong, Suwanna; Mach, Robert H; Xia, Younan | Advanced healthcare materials | 2014 Mar 26 | NULL | 24677807 |
| REST and stress resistance in ageing and Alzheimer's disease. | Lu, Tao; Aron, Liviu; Zullo, Joseph; Pan, Ying; Kim, Haeyoung; Chen, Yiwen; Yang, Tun-Hsiang; Kim, Hyun-Min; Drake, Derek; Liu, X Shirley; Bennett, David A; Colaiacovo, Monica P; Yankner, Bruce A | Nature | 2014 Mar 27 | 448-54 | 24670762 |
| An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. | Brownstein, Catherine A; Beggs, Alan H; Homer, Nils; Merriman, Barry; Yu, Timothy W; Flannery, Katherine C; DeChene, Elizabeth T; Towne, Meghan C; Savage, Sarah K; Price, Emily N; Holm, Ingrid A; Luquette, Lovelace J; Lyon, Elaine; Majzoub, Joseph; Neupert, Peter; McCallie Jr, David; Szolovits, Peter; Willard, Huntington F; Mendelsohn, Nancy J; Temme, Renee; Finkel, Richard S; Yum, Sabrina W; Medne, Livija; Sunyaev, Shamil R; Adzhubey, Ivan; Cassa, Christopher A; de Bakker, Paul I W; Duzkale, Hatice; Dworzy?ski, Piotr; Fairbrother, William; Francioli, Laurent; Funke, Birgit H; Giovanni, Monica A; Handsaker, Robert E; Lage, Kasper; Lebo, Matthew S; Lek, Monkol; Leshchiner, Ignaty; MacArthur, Daniel G; McLaughlin, Heather M; Murray, Michael F; Pers, Tune H; Polak, Paz P; Raychaudhuri, Soumya; Rehm, Heidi L; Soemedi, Rachel; Stitziel, Nathan O; Vestecka, Sara; Supper, Jochen; Gugenmus, Claudia; Klocke, Bernward; Hahn, Alexander; Schubach, Max; Menzel, Mortiz; Biskup, Saskia; Freisinger, Peter; Deng, Mario; Braun, Martin; Perner, Sven; Smith, Richard J H; Andorf, Janeen L; Huang, Jian; Ryckman, Kelli; Sheffield, Val C; Stone, Edwin M; Bair, Thomas; Black-Ziegelbein, E Ann; Braun, Terry A; Darbro, Benjamin; DeLuca, Adam P; Kolbe, Diana L; Scheetz, Todd E; Shearer, Aiden E; Sompallae, Rama; Wang, Kai; Bassuk, Alexander G; Edens, Erik; Mathews, Katherine; Moore, Steven A; Shchelochkov, Oleg A; Trapane, Pamela; Bossler, Aaron; Campbell, Colleen A; Heusel, Jonathan W; Kwitek, Anne; Maga, Tara; Panzer, Karin; Wassink, Thomas; Van Daele, Douglas; Azaiez, Hela; Booth, Kevin; Meyer, Nic; Segal, Michael M; Williams, Marc S; Tromp, Gerard; White, Peter; Corsmeier, Donald; Fitzgerald-Butt, Sara; Herman, Gail; Lamb-Thrush, Devon; McBride, Kim L; Newsom, David; Pierson, Christopher R; Rakowsky, Alexander T; Maver, Ale?; Lovre?i?, Luca; Palanda?i?, Anja; Peterlin, Borut; Torkamani, Ali; Wedell, Anna; Huss, Mikael; Alexeyenko, Andrey; Lindvall, Jessica M; Magnusson, Måns; Nilsson, Daniel; Stranneheim, Henrik; Taylan, Fulya; Gilissen, Christian; Hoischen, Alexander; van Bon, Bregje; Yntema, Helger; Nelen, Marcel; Zhang, Weidong; Sager, Jason; Zhang, Lu; Blair, Kathryn; Kural, Deniz; Cariaso, Michael; Lennon, Greg G; Javed, Asif; Agrawal, Saloni; Ng, Pauline C; Sandhu, Komal S; Krishna, Shuba; Veeramachaneni, Vamsi; Isakov, Ofer; Halperin, Eran; Friedman, Eitan; Shomron, Noam; Glusman, Gustavo; Roach, Jared C; Caballero, Juan; Cox, Hannah C; Mauldin, Denise; Ament, Seth A; Rowen, Lee; Richards, Daniel R; San Lucas, F Anthony; Gonzalez-Garay, Manuel L; Caskey, C Thomas; Bai, Yu; Huang, Ying; Fang, Fang; Zhang, Yan; Wang, Zhengyuan; Barrera, Jorge; Garcia-Lobo, Juan M; González-Lamuño, Domingo; Llorca, Javier; Rodriguez, Maria C; Varela, Ignacio; Reese, Martin G; De La Vega, Francisco M; Kiruluta, Edward; Cargill, Michele; Hart, Reece K; Sorenson, Jon M; Lyon, Gholson J; Stevenson, David A; Bray, Bruce E; Moore, Barry M; Eilbeck, Karen; Yandell, Mark; Zhao, Hongyu; Hou, Lin; Chen, Xiaowei; Yan, Xiting; Chen, Mengjie; Li, Cong; Yang, Can; Gunel, Murat; Li, Peining; Kong, Yong; Alexander, Austin C; Albertyn, Zayed I; Boycott, Kym M; Bulman, Dennis E; Gordon, Paul M K; Innes, A Micheil; Knoppers, Bartha M; Majewski, Jacek; Marshall, Christian R; Parboosingh, Jillian S; Sawyer, Sarah L; Samuels, Mark E; Schwartzentruber, Jeremy; Kohane, Isaac S; Margulies, David M | Genome biology. | 2014 Mar 25; | 24667040 | |
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| The Determinants of Federal and State Enforcement of Workplace Safety Regulations: OSHA Inspections 1990-2010. | Jung, Juergen; Makowsky, Michael D | Journal of regulatory economics | 2014 Feb 1 | Jan-33 | 24659856 |
| Optimizing cardiac resynchronization therapy to minimize ATP consumption heterogeneity throughout the left ventricle: a simulation analysis using a canine heart failure model. | Hu, Yuxuan; Gurev, Viatcheslav; Constantino, Jason; Trayanova, Natalia | Heart rhythm : the official journal of the Heart Rhythm Society. | 2014 Jun; | 1063-9 | 24657430 |
| Whole-brain activity maps reveal stereotyped, distributed networks for visuomotor behavior. | Portugues, Ruben; Feierstein, Claudia E; Engert, Florian; Orger, Michael B | Neuron | 2014 Mar 19 | 1328-43 | 24656252 |
| Metabolic regulation of immune responses. | Ganeshan, Kirthana; Chawla, Ajay | Annual review of immunology | 2014 | 609-34 | 24655299 |
| Intention estimation in brain-machine interfaces. | Fan, Joline M; Nuyujukian, Paul; Kao, Jonathan C; Chestek, Cynthia A; Ryu, Stephen I; Shenoy, Krishna V | Journal of neural engineering | 2014 Feb | 16004 | 24654266 |
| Genetically encoded molecular probes to visualize and perturb signaling dynamics in living biological systems. | Sample, Vedangi; Mehta, Sohum; Zhang, Jin | Journal of cell science | 2014 Mar 15 | 1151-60 | 24634506 |
| Reconstitution of contractile actomyosin arrays. | Murrell, Michael; Thoresen, Todd; Gardel, Margaret | Methods in enzymology. | 2014; | 265-82 | 24630112 |
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| Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor. | Yuan, Hsiangkuo; Wilson, Christy M; Xia, Jun; Doyle, Sarah L; Li, Shuqin; Fales, Andrew M; Liu, Yang; Ozaki, Ema; Mulfaul, Kelly; Hanna, Gabi; Palmer, Gregory M; Wang, Lihong V; Grant, Gerald A; Vo-Dinh, Tuan | Nanoscale | 2014 Apr 21 | 4078-82 | 24619405 |
| Subunit composition of glutamate and gamma-aminobutyric acid receptors in status epilepticus. | Loddenkemper, Tobias; Talos, Delia M; Cleary, Ryan T; Joseph, Annelise; Sanchez Fernandez, Ivan; Alexopoulos, Andreas; Kotagal, Prakash; Najm, Imad; Jensen, Frances E | Epilepsy research | 2014 May | 605-15 | 24613745 |
| The transcription factor titration effect dictates level of gene expression. | Brewster, Robert C; Weinert, Franz M; Garcia, Hernan G; Song, Dan; Rydenfelt, Mattias; Phillips, Rob | Cell | 2014 Mar 13 | 1312-23 | 24612990 |
| CMV Infection, TLR-2 and -4 Expression, and Cytokine Profiles in Early-Onset Preeclampsia with HELLP Syndrome. | Xie, Fang; von Dadelszen, Peter; Nadeau, Joseph | American journal of reproductive immunology (New York, N.Y. : 1989) | 2014 Feb 24 | NULL | 24612145 |
| Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign. | Gaj, Thomas; Sirk, Shannon J; Tingle, Ryan D; Mercer, Andrew C; Wallen, Mark C; Barbas 3rd, Carlos F | Journal of the American Chemical Society | 2014 Apr 2 | 5047-56 | 24611715 |
| Cross-linking in the silks of bees, ants and hornets. | Campbell, Peter M; Trueman, Holly E; Zhang, Qiang; Kojima, Katsura; Kameda, Tsunenori; Sutherland, Tara D | Insect biochemistry and molecular biology | 2014 May | 40-50 | 24607851 |
| Dependence of optical scattering from Intralipid in gelatin-gel based tissue-mimicking phantoms on mixing temperature and time. | Lai, Puxiang; Xu, Xiao; Wang, Lihong V | Journal of biomedical optics | 2014 Mar | 35002 | 24604534 |
| Common genetic variants modulate pathogen-sensing responses in human dendritic cells. | Lee, Mark N; Ye, Chun; Villani, Alexandra-Chloe; Raj, Towfique; Li, Weibo; Eisenhaure, Thomas M; Imboywa, Selina H; Chipendo, Portia I; Ran, F Ann; Slowikowski, Kamil; Ward, Lucas D; Raddassi, Khadir; McCabe, Cristin; Lee, Michelle H; Frohlich, Irene Y; H | Science (New York, N.Y.) | 2014 Mar 7 | 1246980 | 24604203 |
| Medicine. Combating evolution to fight disease. | Rosenberg, Susan M; Queitsch, Christine | Science (New York, N.Y.) | 2014 Mar 7 | 1088-9 | 24604189 |
| Maternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring. | Cannon, Matthew V; Buchner, David A; Hester, James; Miller, Hadley; Sehayek, Ephraim; Nadeau, Joseph H; Serre, David | PloS one | 2014 | e90335 | 24594983 |
| Recasting the theory of mosquito-borne pathogen transmission dynamics and control. | Smith, David L; Perkins, T Alex; Reiner Jr, Robert C; Barker, Christopher M; Niu, Tianchan; Chaves, Luis Fernando; Ellis, Alicia M; George, Dylan B; Le Menach, Arnaud; Pulliam, Juliet R C; Bisanzio, Donal; Buckee, Caroline; Chiyaka, Christinah; Cummings, | Transactions of the Royal Society of Tropical Medicine and Hygiene | 2014 Apr | 185-97 | 24591453 |
| Calibration-free absolute quantification of particle concentration by statistical analyses of photoacoustic signals in vivo. | Zhou, Yong; Yao, Junjie; Maslov, Konstantin I; Wang, Lihong V | Journal of biomedical optics | 2014 Mar | 37001 | 24589987 |
| Integrated photoacoustic, confocal, and two-photon microscope. | Rao, Bin; Soto, Florentina; Kerschensteiner, Daniel; Wang, Lihong V | Journal of biomedical optics | 2014 Mar | 36002 | 24589986 |
| Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells. | Elman, Jessica S; Murray, Ryan C; Murray, Ryan M; Wang, Fangjing; Shen, Keyue; Gao, Shan; Conway, Kevin E; Yarmush, Martin L; Tannous, Bakhos A; Weissleder, Ralph; Parekkadan, Biju | PloS one. | 2014; | 24587097 | |
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| Lestaurtinib (CEP-701) attenuates "second hit" kainic acid-induced seizures following early life hypoxic seizures. | Obeid, Makram; Rosenberg, Evan C; Klein, Peter M; Jensen, Frances E | Epilepsy research | 2014 May | 806-10 | 24582454 |
| Statistical mechanical model of coupled transcription from multiple promoters due to transcription factor titration. | Rydenfelt, Mattias; Cox, Robert Sidney; Garcia, Hernan; Phillips, Rob | Physical review. E, Statistical, nonlinear, and soft matter physics | 2014 Jan | 12702 | 24580252 |
| Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway. | Lin, Hsiao-Ching; Tsunematsu, Yuta; Dhingra, Sourabh; Xu, Wei; Fukutomi, Manami; Chooi, Yit-Heng; Cane, David E; Calvo, Ana M; Watanabe, Kenji; Tang, Yi | Journal of the American Chemical Society | 2014 Mar 19 | 4426-36 | 24568283 |
| The future of whole-cell modeling. | Macklin, Derek N; Ruggero, Nicholas A; Covert, Markus W | Current opinion in biotechnology | 2014 Feb 17 | 111-115 | 24556244 |
| Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange. | Burns, Michael C; Sun, Qi; Daniels, R Nathan; Camper, DeMarco; Kennedy, J Phillip; Phan, Jason; Olejniczak, Edward T; Lee, Taekyu; Waterson, Alex G; Rossanese, Olivia W; Fesik, Stephen W | Proceedings of the National Academy of Sciences of the United States of America | 2014 Mar 4 | 3401-6 | 24550516 |
| Kinetic and equilibrium binding characterization of aptamers to small molecules using a label-free, sensitive, and scalable platform. | Chang, Andrew L; McKeague, Maureen; Liang, Joe C; Smolke, Christina D | Analytical chemistry. | 2014 Apr 1; | 3273-8 | 24548121 |
| fast_protein_cluster: parallel and optimized clustering of large-scale protein modeling data. | Hung, Ling-Hong; Samudrala, Ram | Bioinformatics (Oxford, England) | 2014 Jun 15 | 1774-6 | 24532722 |
| Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs. | Adams, Kristin N; Szumowski, John D; Ramakrishnan, Lalita | The Journal of infectious diseases. | 2014 Aug 1; | 456-66 | 24532601 |
| Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity. | Guilinger, John P; Pattanayak, Vikram; Reyon, Deepak; Tsai, Shengdar Q; Sander, Jeffry D; Joung, J Keith; Liu, David R | Nature methods | 2014 Apr | 429-35 | 24531420 |
| Statistical modeling of behavioral dynamics during propofol-induced loss of consciousness. | Wong, Kin Foon Kevin; Smith, Anne C; Pierce, Eric T; Harrell, P Grace; Walsh, John L; Salazar-Gomez, Andres Felipe; Tavares, Casie L; Purdon, Patrick L; Brown, Emery N | Journal of neuroscience methods | 2014 Apr 30 | 65-74 | 24530701 |
| Crystal structure of Cas9 in complex with guide RNA and target DNA. | Nishimasu, Hiroshi; Ran, F Ann; Hsu, Patrick D; Konermann, Silvana; Shehata, Soraya I; Dohmae, Naoshi; Ishitani, Ryuichiro; Zhang, Feng; Nureki, Osamu | Cell | 2014 Feb 27 | 935-49 | 24529477 |
| Structural insights on the role of antibodies in HIV-1 vaccine and therapy. | West Jr, Anthony P; Scharf, Louise; Scheid, Johannes F; Klein, Florian; Bjorkman, Pamela J; Nussenzweig, Michel C | Cell | 2014 Feb 13 | 633-48 | 24529371 |
| Lipid Modulation of Calcium Flux through CaV2.3 Regulates Acrosome Exocytosis and Fertilization. | Cohen, Roy; Buttke, Danielle E; Asano, Atsushi; Mukai, Chinatsu; Nelson, Jacquelyn L; Ren, Dongjun; Miller, Richard J; Cohen-Kutner, Moshe; Atlas, Daphne; Travis, Alexander J | Developmental cell | 2014 Feb 10 | 310-21 | 24525187 |
| Dissecting genomic diversity, one cell at a time. | Blainey, Paul C; Quake, Stephen R | Nature methods | 2014 Jan | 19-21 | 24524132 |
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| Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria. | Pandey, Shree P; Winkler, Jonathan A; Li, Hu; Camacho, Diogo M; Collins, James J; Walker, Graham C | BMC genomics | 2014 | 121 | 24511998 |
| Metabolite Profiling of 5'-AMP-Induced Hypometabolism. | Zhao, Zhaoyang; Van Oort, Anita; Tao, Zhenyin; O'Brien 3rd, William G; Lee, Cheng Chi | Metabolomics : Official journal of the Metabolomic Society | 2014 Feb 1 | 63-76 | 24511307 |
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| Neural circuits as computational dynamical systems. | Sussillo, David | Current opinion in neurobiology | 2014 Apr | 156-63 | 24509098 |
| Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations. | Alami, Nael H; Smith, Rebecca B; Carrasco, Monica A; Williams, Luis A; Winborn, Christina S; Han, Steve S W; Kiskinis, Evangelos; Winborn, Brett; Freibaum, Brian D; Kanagaraj, Anderson; Clare, Alison J; Badders, Nisha M; Bilican, Bilada; Chaum, Edward; Chandran, Siddharthan; Shaw, Christopher E; Eggan, Kevin C; Maniatis, Tom; Taylor, J Paul | Neuron. | 2014 Feb 05; | 24507191 | |
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| RNA Replicon Delivery via Lipid-Complexed PRINT Protein Particles. | Xu, Jing; Luft, J Christopher; Yi, Xianwen; Tian, Shaomin; Owens, Gary; Wang, Jin; Johnson, Ashley; Berglund, Peter; Smith, Jonathan; Napier, Mary E; Desimone, Joseph M | Molecular pharmaceutics | 2013 Aug 21 | NULL | 23924216 |
| Conceptualizing and experiencing compassion. | Condon, Paul; Feldman Barrett, Lisa | Emotion (Washington, D.C.) | 2013 Oct | 817-21 | 23914766 |
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| Epilepsy biomarkers. | Engel Jr, Jerome; Pitkanen, Asla; Loeb, Jeffrey A; Dudek, F Edward; Bertram 3rd, Edward H; Cole, Andrew J; Moshe, Solomon L; Wiebe, Samuel; Jensen, Frances E; Mody, Istvan; Nehlig, Astrid; Vezzani, Annamaria | Epilepsia | 2013 Aug | 61-9 | 23909854 |
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| Issues related to development of antiepileptogenic therapies. | Pitkanen, Asla; Nehlig, Astrid; Brooks-Kayal, Amy R; Dudek, F Edward; Friedman, Daniel; Galanopoulou, Aristea S; Jensen, Frances E; Kaminski, Rafal M; Kapur, Jaideep; Klitgaard, Henrik; Loscher, Wolfgang; Mody, Istvan; Schmidt, Dieter | Epilepsia | 2013 Aug | 35-43 | 23909852 |
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| Microbiota's 'little helpers': bacteriophages and antibiotic-associated responses in the gut microbiome. | Sun, Christine L; Relman, David A | Genome biology. | 2013; | 127 | 23906048 |
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| Calibration-free quantification of absolute oxygen saturation based on the dynamics of photoacoustic signals. | Xia, Jun; Danielli, Amos; Liu, Yan; Wang, Lidai; Maslov, Konstantin; Wang, Lihong V | Optics letters | 2013 Aug 1 | 2800-3 | 23903146 |
| Random-access optical-resolution photoacoustic microscopy using a digital micromirror device. | Liang, Jinyang; Zhou, Yong; Winkler, Amy W; Wang, Lidai; Maslov, Konstantin I; Li, Chiye; Wang, Lihong V | Optics letters | 2013 Aug 1 | 2683-6 | 23903111 |
| Rapidly-dissolvable microneedle patches via a highly scalable and reproducible soft lithography approach. | Moga, Katherine A; Bickford, Lissett R; Geil, Robert D; Dunn, Stuart S; Pandya, Ashish A; Wang, Yapei; Fain, John H; Archuleta, Christine F; O'Neill, Adrian T; Desimone, Joseph M | Advanced materials (Deerfield Beach, Fla.) | 2013 Sep 25 | 5060-6 | 23893866 |
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| Real-time segmentation of burst suppression patterns in critical care EEG monitoring. | Brandon Westover, M; Shafi, Mouhsin M; Ching, Shinung; Chemali, Jessica J; Purdon, Patrick L; Cash, Sydney S; Brown, Emery N | Journal of neuroscience methods | 2013 Sep 30 | 131-41 | 23891828 |
| Local cortical dynamics of burst suppression in the anaesthetized brain. | Lewis, Laura D; Ching, Shinung; Weiner, Veronica S; Peterfreund, Robert A; Eskandar, Emad N; Cash, Sydney S; Brown, Emery N; Purdon, Patrick L | Brain : a journal of neurology | 2013 Sep | 2727-37 | 23887187 |
| Deep-tissue photoacoustic tomography of Forster resonance energy transfer. | Wang, Yu; Xia, Jun; Wang, Lihong V | Journal of biomedical optics | 2013 | 101316 | 23884608 |
| Optical control of mammalian endogenous transcription and epigenetic states. | Konermann, Silvana; Brigham, Mark D; Trevino, Alexandro E; Hsu, Patrick D; Heidenreich, Matthias; Cong, Le; Platt, Randall J; Scott, David A; Church, George M; Zhang, Feng | Nature | 2013 Aug 22 | 472-6 | 23877069 |
| Heritable and precise zebrafish genome editing using a CRISPR-Cas system. | Hwang, Woong Y; Fu, Yanfang; Reyon, Deepak; Maeder, Morgan L; Kaini, Prakriti; Sander, Jeffry D; Joung, J Keith; Peterson, Randall T; Yeh, Jing-Ruey Joanna | PloS one | 2013 | e68708 | 23874735 |
| An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection. | Tobin, David M; Roca, Francisco J; Ray, John P; Ko, Dennis C; Ramakrishnan, Lalita | PloS one | 2013 | e67828 | 23874453 |
| DNA targeting specificity of RNA-guided Cas9 nucleases. | Hsu, Patrick D; Scott, David A; Weinstein, Joshua A; Ran, F Ann; Konermann, Silvana; Agarwala, Vineeta; Li, Yinqing; Fine, Eli J; Wu, Xuebing; Shalem, Ophir; Cradick, Thomas J; Marraffini, Luciano A; Bao, Gang; Zhang, Feng | Nature biotechnology | 2013 Sep | 827-32 | 23873081 |
| Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor. | Peng, Tien; Tian, Ying; Boogerd, Cornelis J; Lu, Min Min; Kadzik, Rachel S; Stewart, Kathleen M; Evans, Sylvia M; Morrisey, Edward E | Nature | 2013 Aug 29 | 589-92 | 23873040 |
| Structure prediction of partial-length protein sequences. | Laurenzi, Adrian; Hung, Ling-Hong; Samudrala, Ram | International journal of molecular sciences | 2013 | 14892-907 | 23867606 |
| Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation. | Witt, Rochelle M; Hecht, Marie-Lyn; Pazyra-Murphy, Maria F; Cohen, Samuel M; Noti, Christian; van Kuppevelt, Toin H; Fuller, Maria; Chan, Jennifer A; Hopwood, John J; Seeberger, Peter H; Segal, Rosalind A | The Journal of biological chemistry | 2013 Sep 6 | 26275-88 | 23867465 |
| A coaxial optrode as multifunction write-read probe for optogenetic studies in non-human primates. | Ozden, Ilker; Wang, Jing; Lu, Yao; May, Travis; Lee, Joonhee; Goo, Werapong; O'Shea, Daniel J; Kalanithi, Paul; Diester, Ilka; Diagne, Mohamed; Deisseroth, Karl; Shenoy, Krishna V; Nurmikko, Arto V | Journal of neuroscience methods | 2013 Sep 30 | 142-54 | 23867081 |
| RNA interference knockdown of DNA methyl-transferase 3 affects gene alternative splicing in the honey bee. | Li-Byarlay, Hongmei; Li, Yang; Stroud, Hume; Feng, Suhua; Newman, Thomas C; Kaneda, Megan; Hou, Kirk K; Worley, Kim C; Elsik, Christine G; Wickline, Samuel A; Jacobsen, Steven E; Ma, Jian; Robinson, Gene E | Proceedings of the National Academy of Sciences of the United States of America | 2013 Jul 30 | 12750-5 | 23852726 |
| A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. | Chiu, Isaac M; Morimoto, Emiko T A; Goodarzi, Hani; Liao, Jennifer T; O'Keeffe, Sean; Phatnani, Hemali P; Muratet, Michael; Carroll, Michael C; Levy, Shawn; Tavazoie, Saeed; Myers, Richard M; Maniatis, Tom | Cell reports | 2013 Jul 25 | 385-401 | 23850290 |
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| TB: the Yin and Yang of lipid mediators. | Tobin, David M; Ramakrishnan, Lalita | Current opinion in pharmacology | 2013 Aug | 641-5 | 23849093 |
| Dysbiosis of the gut microbiota is associated with hiv disease progression and tryptophan catabolism. | Vujkovic-Cvijin, Ivan; Dunham, Richard M; Iwai, Shoko; Maher, Michael C; Albright, Rebecca G; Broadhurst, Mara J; Hernandez, Ryan D; Lederman, Michael M; Huang, Yong; Somsouk, Ma; Deeks, Steven G; Hunt, Peter W; Lynch, Susan V; McCune, Joseph M | Science translational medicine | 2013 Jul 10 | 193ra91 | 23843452 |
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| The developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vector. | Akbari, Omar S; Antoshechkin, Igor; Amrhein, Henry; Williams, Brian; Diloreto, Race; Sandler, Jeremy; Hay, Bruce A | G3 (Bethesda, Md.) | 2013 Sep | 1493-509 | 23833213 |
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| Modeling Spatial Correlation of DNA Deformation: DNA Allostery in Protein Binding. | Xu, Xinliang; Ge, Hao; Gu, Chan; Gao, Yi Qin; Wang, Siyuan S; Thio, Beng Joo Reginald; Hynes, James T; Xie, X Sunney; Cao, Jianshu | The journal of physical chemistry. B | 2013 Jul 8 | NULL | 23795567 |
| High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. | Fu, Yanfang; Foden, Jennifer A; Khayter, Cyd; Maeder, Morgan L; Reyon, Deepak; Joung, J Keith; Sander, Jeffry D | Nature biotechnology | 2013 Jun 23 | NULL | 23792628 |
| GABAergic lateral interactions tune the early stages of visual processing in Drosophila. | Freifeld, Limor; Clark, Damon A; Schnitzer, Mark J; Horowitz, Mark A; Clandinin, Thomas R | Neuron | 2013 Jun 19 | 1075-89 | 23791198 |
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| Real-time Closed-loop Control in a Rodent Model of Medically Induced Coma Using Burst Suppression. | Ching, Shinung; Liberman, Max Y; Chemali, Jessica J; Westover, M Brandon; Kenny, Jonathan; Solt, Ken; Purdon, Patrick L; Brown, Emery N | Anesthesiology | 2013 Jun 13 | NULL | 23770601 |
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| Specific kinematics and motor-related neurons for aversive chemotaxis in Drosophila. | Gao, Xiaojing J; Potter, Christopher J; Gohl, Daryl M; Silies, Marion; Katsov, Alexander Y; Clandinin, Thomas R; Luo, Liqun | Current biology : CB | 2013 Jul 8 | 1163-72 | 23770185 |
| Microbial persistence and the road to drug resistance. | Cohen, Nadia R; Lobritz, Michael A; Collins, James J | Cell host & microbe | 2013 Jun 12 | 632-42 | 23768488 |
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| Discovery of Cryptic Polyketide Metabolites from Dermatophytes Using Heterologous Expression in Aspergillus nidulans. | Yin, Wen-Bing; Chooi, Yit Heng; Smith, Adam R; Cacho, Ralph A; Hu, Youcai; White, Theodore C; Tang, Yi | ACS synthetic biology | 2013 Jun 11 | 23758576 | |
| Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues. | West Jr, Anthony P; Scharf, Louise; Horwitz, Joshua; Klein, Florian; Nussenzweig, Michel C; Bjorkman, Pamela J | Proceedings of the National Academy of Sciences of the United States of America | 2013 Jun 10 | 23754383 | |
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| Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome. | Modi, Sheetal R; Lee, Henry H; Spina, Catherine S; Collins, James J | Nature | 2013 Jun 9 | NULL | 23748443 |
| A closed-loop anesthetic delivery system for real-time control of burst suppression. | Liberman, Max Y; Ching, Shinung; Chemali, Jessica; Brown, Emery N | Journal of neural engineering | 2013 Aug | 46004 | 23744607 |
| HCN4 dynamically marks the first heart field and conduction system precursors. | Liang, Xingqun; Wang, Gang; Lin, Lizhu; Lowe, Jennifer; Zhang, Qingquan; Bu, Lei; Chen, Yihan; Chen, Ju; Sun, Yunfu; Evans, Sylvia M | Circulation research | 2013 Aug 2 | 399-407 | 23743334 |
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| A Reactive Oxygen Species (ROS)-Responsive Polymer for Safe, Efficient, and Targeted Gene Delivery in Cancer Cells. | Shim, Min Suk; Xia, Younan | Angewandte Chemie (International ed. in English) | 2013 Jul 1 | 6926-9 | 23716349 |
| Untangling the web: the diverse functions of the PIWI/piRNA pathway. | Mani, Sneha Ramesh; Juliano, Celina E | Molecular reproduction and development | 2013 Aug | 632-64 | 23712694 |
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| Connection between Oligomeric State and Gating Characteristics of Mechanosensitive Ion Channels. | Haselwandter, Christoph A; Phillips, Rob | PLoS computational biology | 2013 May | e1003055 | 23696720 |
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| Perfusion Imaging of Focal Cortical Dysplasia Using Arterial Spin Labeling: Correlation With Histopathological Vascular Density. | Wintermark, Pia; Lechpammer, Mirna; Warfield, Simon K; Kosaras, Bela; Takeoka, Masanori; Poduri, Annapurna; Madsen, Joseph R; Bergin, Ann M; Whalen, Stephen; Jensen, Frances E | Journal of child neurology | 2013 Nov | 1474-1482 | 23696629 |
| Evolutionary dynamics and information hierarchies in biological systems. | Walker, Sara Imari; Callahan, Benjamin J; Arya, Gaurav; Barry, J David; Bhattacharya, Tanmoy; Grigoryev, Sergei; Pellegrini, Matteo; Rippe, Karsten; Rosenberg, Susan M | Annals of the New York Academy of Sciences | 2013 May 20 | 23691975 | |
| Functional diversity among sensory receptors in a Drosophila olfactory circuit. | Mathew, Dennis; Martelli, Carlotta; Kelley-Swift, Elizabeth; Brusalis, Christopher; Gershow, Marc; Samuel, Aravinthan D T; Emonet, Thierry; Carlson, John R | Proceedings of the National Academy of Sciences of the United States of America. | 2013 Jun 04; | 23690583 | |
| Fragment-based drug discovery using NMR spectroscopy. | Harner, Mary J; Frank, Andreas O; Fesik, Stephen W | Journal of biomolecular NMR | 2013 May 18 | 23686385 | |
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| Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells. | Shalek, Alex K; Satija, Rahul; Adiconis, Xian; Gertner, Rona S; Gaublomme, Jellert T; Raychowdhury, Raktima; Schwartz, Schraga; Yosef, Nir; Malboeuf, Christine; Lu, Diana; Trombetta, John J; Gennert, Dave; Gnirke, Andreas; Goren, Alon; Hacohen, Nir; Levin | Nature | 2013 Jun 13 | 236-40 | 23685454 |
| An unsolved mystery: The target-recognizing RNA species of microRNA genes. | Chen, Chang-Zheng | Biochimie | 2013 May 14 | 23685275 | |
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| Activity-dependent gene expression in honey bee mushroom bodies in response to orientation flight. | Lutz, Claudia C; Robinson, Gene E | The Journal of experimental biology | 2013 Jun 1 | 2031-8 | 23678099 |
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