Search Result
NIH Director's Early Independence Award Program (48)
| Publication Title | Authors | Journal | Publication Date | Page No | PubMedID |
|---|---|---|---|---|---|
| Careful use of science to advance the debate on the UK Cancer Drugs Fund. | Lakdawalla, Darius N; Jena, Anupam B; Doctor, Jason N | JAMA : the journal of the American Medical Association | 2014 Jan 1 | 25-6 | 24381964 |
| Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System. | Chen, Baohui; Gilbert, Luke A; Cimini, Beth A; Schnitzbauer, Joerg; Zhang, Wei; Li, Gene-Wei; Park, Jason; Blackburn, Elizabeth H; Weissman, Jonathan S; Qi, Lei S; Huang, Bo | Cell | 2013 Dec 19 | 1479-91 | 24360272 |
| Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis. | Alenghat, Theresa; Osborne, Lisa C; Saenz, Steven A; Kobuley, Dmytro; Ziegler, Carly G K; Mullican, Shannon E; Choi, Inchan; Grunberg, Stephanie; Sinha, Rohini; Wynosky-Dolfi, Meghan; Snyder, Annelise; Giacomin, Paul R; Joyce, Karen L; Hoang, Tram B; Bewt | Nature | 2013 Dec 5 | 153-7 | 24185009 |
| Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells. | Blum, Jordan M; Ano, Leonor; Li, Zhizhong; Van Mater, David; Bennett, Brian D; Sachdeva, Mohit; Lagutina, Irina; Zhang, Minsi; Mito, Jeffrey K; Dodd, Leslie G; Cardona, Diana M; Dodd, Rebecca D; Williams, Nerissa; Ma, Yan; Lepper, Christoph; Linardic, Cor | Cell reports | 2013 Nov 27 | 933-40 | 24239359 |
| Pd-Porphyrin-Cross-Linked Implantable Hydrogels with Oxygen-Responsive Phosphorescence. | Huang, Haoyuan; Song, Wentao; Chen, Guanying; Reynard, Justin M; Ohulchanskyy, Tymish Y; Prasad, Paras N; Bright, Frank V; Lovell, Jonathan F | Advanced healthcare materials | 2013 Nov 20 | NULL | 24259519 |
| Myf5-positive satellite cells contribute to Pax7-dependent long-term maintenance of adult muscle stem cells. | Gunther, Stefan; Kim, Johnny; Kostin, Sawa; Lepper, Christoph; Fan, Chen-Ming; Braun, Thomas | Cell stem cell | 2013 Nov 7 | 590-601 | 23933088 |
| Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system. | Tzur, Yonatan B; Friedland, Ari E; Nadarajan, Saravanapriah; Church, George M; Calarco, John A; Colaiacovo, Monica P | Genetics | 2013 Nov | 1181-5 | 23979579 |
| Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1* via caspase-8 in dendritic cells. | Antonopoulos, Christina; El Sanadi, Caroline; Kaiser, William J; Mocarski, Edward S; Dubyak, George R | Journal of immunology (Baltimore, Md. : 1950) | 2013 Nov 1 | 4789-803 | 24078693 |
| Editorial: New tricks for innate lymphoid cells. | Sonnenberg, Gregory F | Journal of leukocyte biology | 2013 Nov | 862-4 | 24179147 |
| Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL. | Kaiser, William J; Sridharan, Haripriya; Huang, Chunzi; Mandal, Pratyusha; Upton, Jason W; Gough, Peter J; Sehon, Clark A; Marquis, Robert W; Bertin, John; Mocarski, Edward S | The Journal of biological chemistry | 2013 Oct 25 | 31268-79 | 24019532 |
| Genomically recoded organisms expand biological functions. | Lajoie, Marc J; Rovner, Alexis J; Goodman, Daniel B; Aerni, Hans-Rudolf; Haimovich, Adrian D; Kuznetsov, Gleb; Mercer, Jaron A; Wang, Harris H; Carr, Peter A; Mosberg, Joshua A; Rohland, Nadin; Schultz, Peter G; Jacobson, Joseph M; Rinehart, Jesse; Church | Science (New York, N.Y.) | 2013 Oct 18 | 357-60 | 24136966 |
| From Structure to Systems: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II. | Braberg, Hannes; Jin, Huiyan; Moehle, Erica A; Chan, Yujia A; Wang, Shuyi; Shales, Michael; Benschop, Joris J; Morris, John H; Qiu, Chenxi; Hu, Fuqu; Tang, Leung K; Fraser, James S; Holstege, Frank C P; Hieter, Philip; Guthrie, Christine; Kaplan, Craig D; | Cell | 2013 Aug 15 | 775-88 | 23932120 |
| T follicular helper cell dynamics in germinal centers. | Shulman, Ziv; Gitlin, Alexander D; Targ, Sasha; Jankovic, Mila; Pasqual, Giulia; Nussenzweig, Michel C; Victora, Gabriel D | Science (New York, N.Y.) | 2013 Aug 9 | 673-7 | 23887872 |
| Sequencing Y chromosomes resolves discrepancy in time to common ancestor of males versus females. | Poznik, G David; Henn, Brenna M; Yee, Muh-Ching; Sliwerska, Elzbieta; Euskirchen, Ghia M; Lin, Alice A; Snyder, Michael; Quintana-Murci, Lluis; Kidd, Jeffrey M; Underhill, Peter A; Bustamante, Carlos D | Science (New York, N.Y.) | 2013 Aug 2 | 562-5 | 23908239 |
| Meningococcal carriage in the African meningitis belt. | MenAfriCar Consortium; Ali, Oumer; Aseffa, Abraham; Bedru, Ahmed; Lemma, Tsehaynesh; Moti, Tesfaye; Workhu, Alemayehu; Guebre Xabher, Haimanot; Yamuah, Lawrence; Boukary, Rahamatou Moustapha; Collard, Jean-Marc; Dano, Ibrahim Dan; Habiboulaye, Ibrahim; Is | Tropical medicine & international health : TM & IH | 2013 Aug | 968-78 | 23682910 |
| Heritable genome editing in C. elegans via a CRISPR-Cas9 system. | Friedland, Ari E; Tzur, Yonatan B; Esvelt, Kevin M; Colaiacovo, Monica P; Church, George M; Calarco, John A | Nature methods | 2013 Aug | 741-3 | 23817069 |
| Automated identification of functional dynamic contact networks from X-ray crystallography. | van den Bedem, Henry; Bhabha, Gira; Yang, Kun; Wright, Peter E; Fraser, James S | Nature methods | 2013 Aug | 896-902 | 23913260 |
| The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome. | Engreitz, Jesse M; Pandya-Jones, Amy; McDonel, Patrick; Shishkin, Alexander; Sirokman, Klara; Surka, Christine; Kadri, Sabah; Xing, Jeffrey; Goren, Alon; Lander, Eric S; Plath, Kathrin; Guttman, Mitchell | Science (New York, N.Y.) | 2013 Jul 4 | NULL | 23828888 |
| Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. | Guttman, Mitchell; Russell, Pamela; Ingolia, Nicholas T; Weissman, Jonathan S; Lander, Eric S | Cell | 2013 Jul 3 | 240-51 | 23810193 |
| Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria. | Hepworth, Matthew R; Monticelli, Laurel A; Fung, Thomas C; Ziegler, Carly G K; Grunberg, Stephanie; Sinha, Rohini; Mantegazza, Adriana R; Ma, Hak-Ling; Crawford, Alison; Angelosanto, Jill M; Wherry, E John; Koni, Pandelakis A; Bushman, Frederic D; Elson, | Nature | 2013 Jun 6 | 113-7 | 23698371 |
| Viral modulation of programmed necrosis. | Kaiser, William J; Upton, Jason W; Mocarski, Edward S | Current opinion in virology | 2013 Jun | 296-306 | 23773332 |
| T cell factor 1 is required for group 2 innate lymphoid cell generation. | Yang, Qi; Monticelli, Laurel A; Saenz, Steven A; Chi, Anthony Wei-Shine; Sonnenberg, Gregory F; Tang, Jiangbo; De Obaldia, Maria Elena; Bailis, Will; Bryson, Jerrod L; Toscano, Kristin; Huang, Jian; Haczku, Angela; Pear, Warren S; Artis, David; Bhandoola, | Immunity | 2013 Apr 18 | 694-704 | 23601684 |
| Heritable remodeling of yeast multicellularity by an environmentally responsive prion. | Holmes, Daniel L; Lancaster, Alex K; Lindquist, Susan; Halfmann, Randal | Cell | 2013 Mar 28 | 153-65 | 23540696 |
| Priorities for research on meningococcal disease and the impact of serogroup A vaccination in the African meningitis belt. | Dakar discussion group on priorities for research on epidemic meningococcal disease in Africa; Altmann, Danny; Aseffa, Abraham; Bash, Margaret; Basta, Nicole; Borrow, Ray; Broome, Claire; Caugant, Dominique; Clark, Tom; Collard, Jean-Marc; Djingarey, Mamo | Vaccine | 2013 Mar 1 | 1453-7 | 23273967 |
| Resistin-like molecule ýý promotes pathogenic Th17 cell responses and bacterial-induced intestinal inflammation. | Osborne, Lisa C; Joyce, Karen L; Alenghat, Theresa; Sonnenberg, Gregory F; Giacomin, Paul R; Du, Yurong; Bergstrom, Kirk S; Vallance, Bruce A; Nair, Meera G | Journal of immunology (Baltimore, Md. : 1950) | 2013 Mar 1 | 2292-300 | 23355735 |
| TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation. | Kim, Brian S; Siracusa, Mark C; Saenz, Steven A; Noti, Mario; Monticelli, Laurel A; Sonnenberg, Gregory F; Hepworth, Matthew R; Van Voorhees, Abby S; Comeau, Michael R; Artis, David | Science translational medicine | 2013 Jan 30 | 170ra16 | 23363980 |
| From systems to structure: bridging networks and mechanism. | Fraser, James S; Gross, John D; Krogan, Nevan J | Molecular cell | 2013 Jan 24 | 222-31 | 23352243 |
| Genome-scale engineering for systems and synthetic biology. | Esvelt, Kevin M; Wang, Harris H | Molecular systems biology | 2013 | 641 | 23340847 |
| Flexible backbone sampling methods to model and design protein alternative conformations. | Ollikainen, Noah; Smith, Colin A; Fraser, James S; Kortemme, Tanja | Methods in enzymology | 2013 | 61-85 | 23422426 |
| Penalized unsupervised learning with outliers. | Witten, Daniela M | Statistics and its interface | 2013 | 211-221 | 23875057 |
| Reproducibility of cine displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance for measuring left ventricular strains, torsion, and synchrony in mice. | Haggerty, Christopher M; Kramer, Sage P; Binkley, Cassi M; Powell, David K; Mattingly, Andrea C; Charnigo, Richard; Epstein, Frederick H; Fornwalt, Brandon K | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance | 2013 | 71 | 23981339 |
| Methods for identifying Neisseria meningitidis carriers: a multi-center study in the African meningitis belt. | Basta, Nicole E; Stuart, James M; Nascimento, Maria C; Manigart, Olivier; Trotter, Caroline; Hassan-King, Musa; Chandramohan, Daniel; Sow, Samba O; Berthe, Abdoulaye; Bedru, Ahmed; Tekletsion, Yenenesh K; Collard, Jean-Marc; Jusot, Jean-Francois; Diallo, | PloS one | 2013 | e78336 | 24194921 |
| Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease. | Sonnenberg, Gregory F; Artis, David | Immunity | 2012 Oct 19 | 601-10 | 23084357 |
| The satellite cell builds its nest under Notch's guidance. | Lepper, Christoph; Low, SiewHui; Partridge, Terence A | Cell stem cell | 2012 Oct 5 | 443-4 | 23040471 |
| Engineering ecosystems and synthetic ecologies. | Mee, Michael T; Wang, Harris H | Molecular bioSystems | 2012 Oct | 2470-83 | 22722235 |
| CheShift-2 resolves a local inconsistency between two X-ray crystal structures. | Vila, Jorge A; Sue, Shih-Che; Fraser, James S; Scheraga, Harold A; Dyson, H Jane | Journal of biomolecular NMR | 2012 Oct | 193-8 | 22945426 |
| Prion formation by a yeast GLFG nucleoporin. | Halfmann, Randal; Wright, Jessica R; Alberti, Simon; Lindquist, Susan; Rexach, Michael | Prion | 2012 Sep-Oct | 391-9 | 22561191 |
| Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection. | Carr, Peter A; Wang, Harris H; Sterling, Bram; Isaacs, Farren J; Lajoie, Marc J; Xu, George; Church, George M; Jacobson, Joseph M | Nucleic acids research | 2012 Sep 1 | e132 | 22638574 |
| Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway. | Lee, Se-Jin; Huynh, Thanh V; Lee, Yun-Sil; Sebald, Suzanne M; Wilcox-Adelman, Sarah A; Iwamori, Naoki; Lepper, Christoph; Matzuk, Martin M; Fan, Chen-Ming | Proceedings of the National Academy of Sciences of the United States of America | 2012 Aug 28 | E2353-60 | 22869749 |
| Molecular signatures from omics data: from chaos to consensus. | Sung, Jaeyun; Wang, Yuliang; Chandrasekaran, Sriram; Witten, Daniela M; Price, Nathan D | Biotechnology journal | 2012 Aug | 946-57 | 22528809 |
| Systematic functional prioritization of protein posttranslational modifications. | Beltrao, Pedro; Albanese, Veronique; Kenner, Lillian R; Swaney, Danielle L; Burlingame, Alma; Villen, Judit; Lim, Wendell A; Fraser, James S; Frydman, Judith; Krogan, Nevan J | Cell | 2012 Jul 20 | 413-25 | 22817900 |
| Linking data and models: the importance of statistical analyses to inform models for the transmission dynamics of infections. | Pitzer, Virginia E; Basta, Nicole E | Epidemiology (Cambridge, Mass.) | 2012 Jul | 520-2 | 22659545 |
| Global connectivity of prefrontal cortex predicts cognitive control and intelligence. | Cole, Michael W; Yarkoni, Tal; Repovs, Grega; Anticevic, Alan; Braver, Todd S | The Journal of neuroscience : the official journal of the Society for Neuroscience | 2012 Jun 27 | 8988-99 | 22745498 |
| Genome-scale promoter engineering by coselection MAGE. | Wang, Harris H; Kim, Hwangbeom; Cong, Le; Jeong, Jaehwan; Bang, Duhee; Church, George M | Nature methods | 2012 Jun | 591-3 | 22484848 |
| On the assessment of statistical significance of three-dimensional colocalization of sets of genomic elements. | Witten, Daniela M; Noble, William Stafford | Nucleic acids research | 2012 May | 3849-55 | 22266657 |
| Massively parallel functional dissection of mammalian enhancers in vivo. | Patwardhan, Rupali P; Hiatt, Joseph B; Witten, Daniela M; Kim, Mee J; Smith, Robin P; May, Dalit; Lee, Choli; Andrie, Jennifer M; Lee, Su-In; Cooper, Gregory M; Ahituv, Nadav; Pennacchio, Len A; Shendure, Jay | Nature biotechnology | 2012 Mar | 265-70 | 22371081 |
| Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multi-enzyme catalysis. | Wang, Harris H; Huang, Po-Yi; Xu, George; Haas, Wilhelm; Marblestone, Adam; Li, Jun; Gygi, Steven; Forster, Anthony C; Jewett, Michael C; Church, George M | ACS synthetic biology | 2012 Feb 16 | 43-52 | 22737598 |
| Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases. | Mosberg, Joshua A; Gregg, Christopher J; Lajoie, Marc J; Wang, Harris H; Church, George M | PloS one | 2012 | e44638 | 22957093 |
