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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Author Journal Name PubMedID Journal Abbreviation Publication Date PubMedLink
Metabolic plasticity drives development during mammalian embryogenesis. Sharpley MS, Chi F, Hoeve JT, Banerjee U Developmental cell 34428399 Dev Cell 2021 Aug 23 https://www.ncbi.nlm.nih.gov/pubmed/34428399
Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis. Chi F, Sharpley MS, Nagaraj R, Roy SS, Banerjee U Developmental cell 32197068 Dev Cell 2020 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/32197068
Reversible switching between epigenetic states in honeybee behavioral subcastes. Herb BR, Wolschin F, Hansen KD, Aryee MJ, Langmead B, Irizarry R, Amdam GV, Feinberg AP Nature neuroscience 22983211 Nat Neurosci 2012 Oct https://www.ncbi.nlm.nih.gov/pubmed/22983211
Regulated noise in the epigenetic landscape of development and disease. Pujadas E, Feinberg AP Cell 22424224 Cell 2012 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/22424224
The glove-like structure of the conserved membrane protein TatC provides insight into signal sequence recognition in twin-arginine translocation. Ramasamy S, Abrol R, Suloway CJ, Clemons WM Jr Structure (London, England : 1993) 23583035 Structure 2013 May 7 https://www.ncbi.nlm.nih.gov/pubmed/23583035
Minimal requirements for inhibition of MraY by lysis protein E from bacteriophage ΦX174. Tanaka S, Clemons WM Jr Molecular microbiology 22742425 Mol Microbiol 2012 Sep https://www.ncbi.nlm.nih.gov/pubmed/22742425
The evolution of bacterial mechanosensitive channels. Booth IR, Miller S, Müller A, Lehtovirta-Morley L Cell calcium 25591932 Cell Calcium 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25591932
Principles of connectivity among morphologically defined cell types in adult neocortex. Jiang X, Shen S, Cadwell CR, Berens P, Sinz F, Ecker AS, Patel S, Tolias AS Science (New York, N.Y.) 26612957 Science 2015 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/26612957
On the Structure of Neuronal Population Activity under Fluctuations in Attentional State. Ecker AS, Denfield GH, Bethge M, Tolias AS The Journal of neuroscience : the official journal of the Society for Neuroscience 26843656 J Neurosci 2016 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/26843656
Multimodal profiling of single-cell morphology, electrophysiology, and gene expression using Patch-seq. Cadwell CR, Scala F, Li S, Livrizzi G, Shen S, Sandberg R, Jiang X, Tolias AS Nature protocols 29189773 Nat Protoc 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/29189773
Waking State: Rapid Variations Modulate Neural and Behavioral Responses. McGinley MJ, Vinck M, Reimer J, Batista-Brito R, Zagha E, Cadwell CR, Tolias AS, Cardin JA, McCormick DA Neuron 26402600 Neuron 2015 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/26402600
Pupil fluctuations track fast switching of cortical states during quiet wakefulness. Reimer J, Froudarakis E, Cadwell CR, Yatsenko D, Denfield GH, Tolias AS Neuron 25374359 Neuron 2014 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/25374359
Improved estimation and interpretation of correlations in neural circuits. Yatsenko D, Josić K, Ecker AS, Froudarakis E, Cotton RJ, Tolias AS PLoS computational biology 25826696 PLoS Comput Biol 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25826696
Learning divisive normalization in primary visual cortex. Burg MF, Cadena SA, Denfield GH, Walker EY, Tolias AS, Bethge M, Ecker AS PLoS computational biology 34097695 PLoS Comput Biol 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34097695
Benchmarking Spike Rate Inference in Population Calcium Imaging. Theis L, Berens P, Froudarakis E, Reimer J, Román Rosón M, Baden T, Euler T, Tolias AS, Bethge M Neuron 27151639 Neuron 2016 May 4 https://www.ncbi.nlm.nih.gov/pubmed/27151639
Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq. Cadwell CR, Palasantza A, Jiang X, Berens P, Deng Q, Yilmaz M, Reimer J, Shen S, Bethge M, Tolias KF, Sandberg R, Tolias AS Nature biotechnology 26689543 Nat Biotechnol 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26689543
Attentional fluctuations induce shared variability in macaque primary visual cortex. Denfield GH, Ecker AS, Shinn TJ, Bethge M, Tolias AS Nature communications 29985411 Nat Commun 2018 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/29985411
Deep convolutional models improve predictions of macaque V1 responses to natural images. Cadena SA, Denfield GH, Walker EY, Gatys LA, Tolias AS, Bethge M, Ecker AS PLoS computational biology 31013278 PLoS Comput Biol 2019 Apr https://www.ncbi.nlm.nih.gov/pubmed/31013278
Population code in mouse V1 facilitates readout of natural scenes through increased sparseness. Froudarakis E, Berens P, Ecker AS, Cotton RJ, Sinz FH, Yatsenko D, Saggau P, Bethge M, Tolias AS Nature neuroscience 24747577 Nat Neurosci 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24747577
Pupil fluctuations track rapid changes in adrenergic and cholinergic activity in cortex. Reimer J, McGinley MJ, Liu Y, Rodenkirch C, Wang Q, McCormick DA, Tolias AS Nature communications 27824036 Nat Commun 2016 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/27824036
Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex. Cadwell CR, Scala F, Fahey PG, Kobak D, Mulherkar S, Sinz FH, Papadopoulos S, Tan ZH, Johnsson P, Hartmanis L, Li S, Cotton RJ, Tolias KF, Sandberg R, Berens P, Jiang X, Tolias AS eLife 32134385 Elife 2020 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/32134385
Perspectives on best practices for gene therapy programs. Cheever TR, Berkley D, Braun S, Brown RH, Byrne BJ, Chamberlain JS, Cwik V, Duan D, Federoff HJ, High KA, Kaspar BK, Klinger KW, Larkindale J, Lincecum J, Mavilio F, McDonald CL, McLaughlin J, Weiss McLeod B, Mendell JR, Nuckolls G, Stedman HH, Tagle DA, Vandenberghe LH, Wang H, Wernett PJ, Wilson JM, Porter JD, Gubitz AK Human gene therapy 25654329 Hum Gene Ther 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25654329
Retinal gene therapy coming of age. Cepko CL, Vandenberghe LH Human gene therapy 23458444 Hum Gene Ther 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23458444
AAV9 targets cone photoreceptors in the nonhuman primate retina. Vandenberghe LH, Bell P, Maguire AM, Xiao R, Hopkins TB, Grant R, Bennett J, Wilson JM PloS one 23382846 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23382846
Efficient transduction and optogenetic stimulation of retinal bipolar cells by a synthetic adeno-associated virus capsid and promoter. Cronin T, Vandenberghe LH, Hantz P, Juttner J, Reimann A, Kacsó AE, Huckfeldt RM, Busskamp V, Kohler H, Lagali PS, Roska B, Bennett J EMBO molecular medicine 25092770 EMBO Mol Med 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25092770
In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector. Zinn E, Pacouret S, Khaychuk V, Turunen HT, Carvalho LS, Andres-Mateos E, Shah S, Shelke R, Maurer AC, Plovie E, Xiao R, Vandenberghe LH Cell reports 26235624 Cell Rep 2015 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/26235624
Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis. Drivas TG, Wojno AP, Tucker BA, Stone EM, Bennett J Science translational medicine 26062849 Sci Transl Med 2015 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/26062849
A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear. Landegger LD, Pan B, Askew C, Wassmer SJ, Gluck SD, Galvin A, Taylor R, Forge A, Stankovic KM, Holt JR, Vandenberghe LH Nature biotechnology 28165475 Nat Biotechnol 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28165475
The Assembly-Activating Protein Promotes Stability and Interactions between AAV's Viral Proteins to Nucleate Capsid Assembly. Maurer AC, Pacouret S, Cepeda Diaz AK, Blake J, Andres-Mateos E, Vandenberghe LH Cell reports 29742436 Cell Rep 2018 May 8 https://www.ncbi.nlm.nih.gov/pubmed/29742436
Restoration of Vision and Retinal Responses After Adeno-Associated Virus-Mediated Optogenetic Therapy in Blind Dogs. Nikonov S, Aravand P, Lyubarsky A, Nikonov R, Luo AJ, Wei Z, Maguire AM, Phelps NT, Shpylchak I, Willett K, Aleman TS, Huckfeldt RM, Ramachandran PS, Bennett J Translational vision science & technology 35604672 Transl Vis Sci Technol 2022 May 2 https://www.ncbi.nlm.nih.gov/pubmed/35604672
Gene delivery to the retina: from mouse to man. Bennett J, Chung DC, Maguire A Methods in enzymology 22365778 Methods Enzymol 2012 https://www.ncbi.nlm.nih.gov/pubmed/22365778
Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids. Castle MJ, Turunen HT, Vandenberghe LH, Wolfe JH Methods in molecular biology (Clifton, N.J.) 26611584 Methods Mol Biol 2016 https://www.ncbi.nlm.nih.gov/pubmed/26611584
Promising and delivering gene therapies for vision loss. Carvalho LS, Vandenberghe LH Vision research 25094052 Vision Res 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25094052
What Is Next for Retinal Gene Therapy? Vandenberghe LH Cold Spring Harbor perspectives in medicine 25877395 Cold Spring Harb Perspect Med 2015 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/25877395
In vitro and in vivo rescue of aberrant splicing in CEP290-associated LCA by antisense oligonucleotide delivery. Garanto A, Chung DC, Duijkers L, Corral-Serrano JC, Messchaert M, Xiao R, Bennett J, Vandenberghe LH, Collin RW Human molecular genetics 27106101 Hum Mol Genet 2016 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/27106101
Adeno-associated virus: fit to serve. Zinn E, Vandenberghe LH Current opinion in virology 25128609 Curr Opin Virol 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25128609
Structured Variability in Purkinje Cell Activity during Locomotion. Sauerbrei BA, Lubenov EV, Siapas AG Neuron 26291165 Neuron 2015 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/26291165
Spatial tuning and brain state account for dorsal hippocampal CA1 activity in a non-spatial learning task. Shan KQ, Lubenov EV, Papadopoulou M, Siapas AG eLife 27487561 Elife 2016 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/27487561
Nanofabricated Neural Probes for Dense 3-D Recordings of Brain Activity. Rios G, Lubenov EV, Chi D, Roukes ML, Siapas AG Nano letters 27766885 Nano Lett 2016 Nov 9 https://www.ncbi.nlm.nih.gov/pubmed/27766885
Brain State Dependence of Hippocampal Subthreshold Activity in Awake Mice. Hulse BK, Lubenov EV, Siapas AG Cell reports 28052244 Cell Rep 2017 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/28052244
Model-based spike sorting with a mixture of drifting t-distributions. Shan KQ, Lubenov EV, Siapas AG Journal of neuroscience methods 28652008 J Neurosci Methods 2017 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/28652008
Membrane Potential Dynamics of CA1 Pyramidal Neurons during Hippocampal Ripples in Awake Mice. Hulse BK, Moreaux LC, Lubenov EV, Siapas AG Neuron 26889811 Neuron 2016 Feb 17 https://www.ncbi.nlm.nih.gov/pubmed/26889811
Endogenous Retroviral Envelope Syncytin Induces HIV-1 Spreading and Establishes HIV Reservoirs in Placenta. Tang Y, Woodward BO, Pastor L, George AM, Petrechko O, Nouvet FJ, Haas DW, Jiang G, Hildreth JEK Cell reports 32234485 Cell Rep 2020 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/32234485
Large-scale imaging in small brains. Ahrens MB, Engert F Current opinion in neurobiology 25636154 Curr Opin Neurobiol 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25636154
Spinal projection neurons control turning behaviors in zebrafish. Huang KH, Ahrens MB, Dunn TW, Engert F Current biology : CB 23910662 Curr Biol 2013 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/23910662
Bipolar cell-photoreceptor connectivity in the zebrafish (Danio rerio) retina. Li YN, Tsujimura T, Kawamura S, Dowling JE The Journal of comparative neurology 22907678 J Comp Neurol 2012 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/22907678
Neural Circuits Underlying Visually Evoked Escapes in Larval Zebrafish. Dunn TW, Gebhardt C, Naumann EA, Riegler C, Ahrens MB, Engert F, Del Bene F Neuron 26804997 Neuron 2016 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/26804997
Navigational strategies underlying phototaxis in larval zebrafish. Chen X, Engert F Frontiers in systems neuroscience 24723859 Front Syst Neurosci 2014 https://www.ncbi.nlm.nih.gov/pubmed/24723859
A compressed sensing framework for efficient dissection of neural circuits. Lee JB, Yonar A, Hallacy T, Shen CH, Milloz J, Srinivasan J, Kocabas A, Ramanathan S Nature methods 30573831 Nat Methods 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30573831
Pluripotency factors in embryonic stem cells regulate differentiation into germ layers. Thomson M, Liu SJ, Zou LN, Smith Z, Meissner A, Ramanathan S Cell 21663792 Cell 2011 Jun 10 https://www.ncbi.nlm.nih.gov/pubmed/21663792
Identification of the long, edited dsRNAome of LPS-stimulated immune cells. Blango MG, Bass BL Genome research 27197207 Genome Res 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27197207
Drosophila dicer-2 cleavage is mediated by helicase- and dsRNA termini-dependent states that are modulated by Loquacious-PD. Sinha NK, Trettin KD, Aruscavage PJ, Bass BL Molecular cell 25891075 Mol Cell 2015 May 7 https://www.ncbi.nlm.nih.gov/pubmed/25891075
Potential role for snoRNAs in PKR activation during metabolic stress. Youssef OA, Safran SA, Nakamura T, Nix DA, Hotamisligil GS, Bass BL Proceedings of the National Academy of Sciences of the United States of America 25848059 Proc Natl Acad Sci U S A 2015 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/25848059
Genome-wide profiling of the C. elegans dsRNAome. Whipple JM, Youssef OA, Aruscavage PJ, Nix DA, Hong C, Johnson WE, Bass BL RNA (New York, N.Y.) 25805852 RNA 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25805852
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress. Saikia M, Krokowski D, Guan BJ, Ivanov P, Parisien M, Hu GF, Anderson P, Pan T, Hatzoglou M The Journal of biological chemistry 23086926 J Biol Chem 2012 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/23086926
Disease tolerance as a defense strategy. Medzhitov R, Schneider DS, Soares MP Science (New York, N.Y.) 22363001 Science 2012 Feb 24 https://www.ncbi.nlm.nih.gov/pubmed/22363001
How the fly balances its ability to combat different pathogens. Chambers MC, Lightfield KL, Schneider DS PLoS pathogens 23271964 PLoS Pathog 2012 https://www.ncbi.nlm.nih.gov/pubmed/23271964
Tolerance of infections. Ayres JS, Schneider DS Annual review of immunology 22224770 Annu Rev Immunol 2012 https://www.ncbi.nlm.nih.gov/pubmed/22224770
Tracing personalized health curves during infections. Schneider DS PLoS biology 21957398 PLoS Biol 2011 Sep https://www.ncbi.nlm.nih.gov/pubmed/21957398
Guided Homing of Cells in Multi-Photon Microfabricated Bioscaffolds. Skylar-Scott MA, Liu MC, Wu Y, Dixit A, Yanik MF Advanced healthcare materials 27059425 Adv Healthc Mater 2016 May https://www.ncbi.nlm.nih.gov/pubmed/27059425
Cholinergic Signaling Controls Conditioned Fear Behaviors and Enhances Plasticity of Cortical-Amygdala Circuits. Jiang L, Kundu S, Lederman JD, López-Hernández GY, Ballinger EC, Wang S, Talmage DA, Role LW Neuron 27161525 Neuron 2016 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/27161525
Electrophysiological properties of basal forebrain cholinergic neurons identified by genetic and optogenetic tagging. López-Hernández GY, Ananth M, Jiang L, Ballinger EC, Talmage DA, Role LW Journal of neurochemistry 28791701 J Neurochem 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28791701
Targeted gene knockout by direct delivery of zinc-finger nuclease proteins. Gaj T, Guo J, Kato Y, Sirk SJ, Barbas CF 3rd Nature methods 22751204 Nat Methods 2012 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/22751204
Structural characterization of anti-inflammatory immunoglobulin G Fc proteins. Ahmed AA, Giddens J, Pincetic A, Lomino JV, Ravetch JV, Wang LX, Bjorkman PJ Journal of molecular biology 25036289 J Mol Biol 2014 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/25036289
Intra-spike crosslinking overcomes antibody evasion by HIV-1. Galimidi RP, Klein JS, Politzer MS, Bai S, Seaman MS, Nussenzweig MC, West AP Jr, Bjorkman PJ Cell 25635457 Cell 2015 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/25635457
Antibody engineering for increased potency, breadth and half-life. Sievers SA, Scharf L, West AP Jr, Bjorkman PJ Current opinion in HIV and AIDS 25760931 Curr Opin HIV AIDS 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25760931
Structural insights on the role of antibodies in HIV-1 vaccine and therapy. West AP Jr, Scharf L, Scheid JF, Klein F, Bjorkman PJ, Nussenzweig MC Cell 24529371 Cell 2014 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/24529371
Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120. West AP Jr, Diskin R, Nussenzweig MC, Bjorkman PJ Proceedings of the National Academy of Sciences of the United States of America 22745174 Proc Natl Acad Sci U S A 2012 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/22745174
Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues. West AP Jr, Scharf L, Horwitz J, Klein F, Nussenzweig MC, Bjorkman PJ Proceedings of the National Academy of Sciences of the United States of America 23754383 Proc Natl Acad Sci U S A 2013 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/23754383
Design and characterization of structured protein linkers with differing flexibilities. Klein JS, Jiang S, Galimidi RP, Keeffe JR, Bjorkman PJ Protein engineering, design & selection : PEDS 25301959 Protein Eng Des Sel 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25301959
Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange. Burns MC, Sun Q, Daniels RN, Camper D, Kennedy JP, Phan J, Olejniczak ET, Lee T, Waterson AG, Rossanese OW, Fesik SW Proceedings of the National Academy of Sciences of the United States of America 24550516 Proc Natl Acad Sci U S A 2014 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/24550516
Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein. Feldkamp MD, Frank AO, Kennedy JP, Patrone JD, Vangamudi B, Waterson AG, Fesik SW, Chazin WJ Biochemistry 23962067 Biochemistry 2013 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/23962067
Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. Frank AO, Feldkamp MD, Kennedy JP, Waterson AG, Pelz NF, Patrone JD, Vangamudi B, Camper DV, Rossanese OW, Chazin WJ, Fesik SW Journal of medicinal chemistry 24147804 J Med Chem 2013 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/24147804
Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A. Patrone JD, Kennedy JP, Frank AO, Feldkamp MD, Vangamudi B, Pelz NF, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW ACS medicinal chemistry letters 23914285 ACS Med Chem Lett 2013 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/23914285
Fragment-based drug discovery using NMR spectroscopy. Harner MJ, Frank AO, Fesik SW Journal of biomolecular NMR 23686385 J Biomol NMR 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23686385
Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation. Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW Angewandte Chemie (International ed. in English) 22566140 Angew Chem Int Ed Engl 2012 Jun 18 https://www.ncbi.nlm.nih.gov/pubmed/22566140
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS(G12C) Inhibitor. Bröker J, Waterson AG, Smethurst C, Kessler D, Böttcher J, Mayer M, Gmaschitz G, Phan J, Little A, Abbott JR, Sun Q, Gmachl M, Rudolph D, Arnhof H, Rumpel K, Savarese F, Gerstberger T, Mischerikow N, Treu M, Herdeis L, Wunberg T, Gollner A, Weinstabl H, Mantoulidis A, Krämer O, McConnell DB, W Fesik S Journal of medicinal chemistry 36300829 J Med Chem 2022 Nov 10 https://www.ncbi.nlm.nih.gov/pubmed/36300829
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS. Abbott JR, Patel PA, Howes JE, Akan DT, Kennedy JP, Burns MC, Browning CF, Sun Q, Rossanese OW, Phan J, Waterson AG, Fesik SW ACS medicinal chemistry letters 30258545 ACS Med Chem Lett 2018 Sep 13 https://www.ncbi.nlm.nih.gov/pubmed/30258545
MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation. Lee KM, Giltnane JM, Balko JM, Schwarz LJ, Guerrero-Zotano AL, Hutchinson KE, Nixon MJ, Estrada MV, Sánchez V, Sanders ME, Lee T, Gómez H, Lluch A, Pérez-Fidalgo JA, Wolf MM, Andrejeva G, Rathmell JC, Fesik SW, Arteaga CL Cell metabolism 28978427 Cell Metab 2017 Oct 3 https://www.ncbi.nlm.nih.gov/pubmed/28978427
Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design. Friberg A, Vigil D, Zhao B, Daniels RN, Burke JP, Garcia-Barrantes PM, Camper D, Chauder BA, Lee T, Olejniczak ET, Fesik SW Journal of medicinal chemistry 23244564 J Med Chem 2013 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/23244564
A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand. Sun Q, Phan J, Friberg AR, Camper DV, Olejniczak ET, Fesik SW Journal of biomolecular NMR 25087006 J Biomol NMR 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25087006
Drugging the undruggable RAS: Mission possible? Cox AD, Fesik SW, Kimmelman AC, Luo J, Der CJ Nature reviews. Drug discovery 25323927 Nat Rev Drug Discov 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/25323927
Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design. Burke JP, Bian Z, Shaw S, Zhao B, Goodwin CM, Belmar J, Browning CF, Vigil D, Friberg A, Camper DV, Rossanese OW, Lee T, Olejniczak ET, Fesik SW Journal of medicinal chemistry 25844895 J Med Chem 2015 May 14 https://www.ncbi.nlm.nih.gov/pubmed/25844895
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC. Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP Molecular cell 25818646 Mol Cell 2015 May 7 https://www.ncbi.nlm.nih.gov/pubmed/25818646
Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. Sarkar D, Olejniczak ET, Phan J, Coker JA, Sai J, Arnold A, Beesetty Y, Waterson AG, Fesik SW Journal of medicinal chemistry 32673492 J Med Chem 2020 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/32673492
A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A. Souza-Fagundes EM, Frank AO, Feldkamp MD, Dorset DC, Chazin WJ, Rossanese OW, Olejniczak ET, Fesik SW Analytical biochemistry 22197419 Anal Biochem 2012 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/22197419
Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods. Pelz NF, Bian Z, Zhao B, Shaw S, Tarr JC, Belmar J, Gregg C, Camper DV, Goodwin CM, Arnold AL, Sensintaffar JL, Friberg A, Rossanese OW, Lee T, Olejniczak ET, Fesik SW Journal of medicinal chemistry 26878343 J Med Chem 2016 Mar 10 https://www.ncbi.nlm.nih.gov/pubmed/26878343
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A. Patrone JD, Pelz NF, Bates BS, Souza-Fagundes EM, Vangamudi B, Camper DV, Kuznetsov AG, Browning CF, Feldkamp MD, Frank AO, Gilston BA, Olejniczak ET, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW ChemMedChem 26748787 ChemMedChem 2016 Apr 19 https://www.ncbi.nlm.nih.gov/pubmed/26748787
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS. Hodges TR, Abbott JR, Little AJ, Sarkar D, Salovich JM, Howes JE, Akan DT, Sai J, Arnold AL, Browning C, Burns MC, Sobolik T, Sun Q, Beesetty Y, Coker JA, Scharn D, Stadtmueller H, Rossanese OW, Phan J, Waterson AG, McConnell DB, Fesik SW Journal of medicinal chemistry 30205005 J Med Chem 2018 Oct 11 https://www.ncbi.nlm.nih.gov/pubmed/30205005
Discovery of BI-2493, a Pan-KRAS Inhibitor Showing In Vivo Efficacy. Bröker J, Waterson AG, Hodges TR, Abbott JR, Arnold A, Böttcher J, Braun N, Cui J, Fuchs JE, Gerstberger T, Gogg S, Hanner S, Herdeis L, Howell LW, Mantoulidis A, Mayer M, Phan J, Rocchetti F, Sankar K, Sarkar D, Schaaf O, Sensintaffar JL, Sun Q, Wunberg T, Fesik SW Journal of medicinal chemistry 40709733 J Med Chem 2025 Aug 14 https://www.ncbi.nlm.nih.gov/pubmed/40709733
Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors. Lee T, Bian Z, Zhao B, Hogdal LJ, Sensintaffar JL, Goodwin CM, Belmar J, Shaw S, Tarr JC, Veerasamy N, Matulis SM, Koss B, Fischer MA, Arnold AL, Camper DV, Browning CF, Rossanese OW, Budhraja A, Opferman J, Boise LH, Savona MR, Letai A, Olejniczak ET, Fesik SW FEBS letters 27878989 FEBS Lett 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27878989
Fragment-based screening of the bromodomain of ATAD2. Harner MJ, Chauder BA, Phan J, Fesik SW Journal of medicinal chemistry 25314628 J Med Chem 2014 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/25314628
Dynamic states of population activity in prefrontal cortical networks of freely-moving macaque. Milton R, Shahidi N, Dragoi V Nature communications 32327660 Nat Commun 2020 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/32327660
Surpassing fundamental limits of oscillators using nonlinear resonators. Villanueva LG, Kenig E, Karabalin RB, Matheny MH, Lifshitz R, Cross MC, Roukes ML Physical review letters 23679770 Phys Rev Lett 2013 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/23679770
Large-scale integration of nanoelectromechanical systems for gas sensing applications. Bargatin I, Myers EB, Aldridge JS, Marcoux C, Brianceau P, Duraffourg L, Colinet E, Hentz S, Andreucci P, Roukes ML Nano letters 22280452 Nano Lett 2012 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/22280452
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The challenge of connecting the dots in the B.R.A.I.N. Devor A, Bandettini PA, Boas DA, Bower JM, Buxton RB, Cohen LB, Dale AM, Einevoll GT, Fox PT, Franceschini MA, Friston KJ, Fujimoto JG, Geyer MA, Greenberg JH, Halgren E, Hämäläinen MS, Helmchen F, Hyman BT, Jasanoff A, Jernigan TL, Judd LL, Kim SG, Kleinfeld D, Kopell NJ, Kutas M, Kwong KK, Larkum ME, Lo EH, Magistretti PJ, Mandeville JB, Masliah E, Mitra PP, Mobley WC, Moskowitz MA, Nimmerjahn A, Reynolds JH, Rosen BR, Salzberg BM, Schaffer CB, Silva GA, So PT, Spitzer NC, Tootell RB, Van Essen DC, Vanduffel W, Vinogradov SA, Wald LL, Wang LV, Weber B, Yodh AG Neuron 24139032 Neuron 2013 Oct 16 https://www.ncbi.nlm.nih.gov/pubmed/24139032
A polished and reinforced thinned-skull window for long-term imaging of the mouse brain. Shih AY, Mateo C, Drew PJ, Tsai PS, Kleinfeld D Journal of visualized experiments : JoVE 22433225 J Vis Exp 2012 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/22433225
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Automatic identification of fluorescently labeled brain cells for rapid functional imaging. Valmianski I, Shih AY, Driscoll JD, Matthews DW, Freund Y, Kleinfeld D Journal of neurophysiology 20610792 J Neurophysiol 2010 Sep https://www.ncbi.nlm.nih.gov/pubmed/20610792
Characterizing ligand-gated ion channel receptors with genetically encoded Ca2++ sensors. Yamauchi JG, Nemecz Á, Nguyen QT, Muller A, Schroeder LF, Talley TT, Lindstrom J, Kleinfeld D, Taylor P PloS one 21305050 PLoS One 2011 Jan 28 https://www.ncbi.nlm.nih.gov/pubmed/21305050
Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture. Shih AY, Rühlmann C, Blinder P, Devor A, Drew PJ, Friedman B, Knutsen PM, Lyden PD, Mateo C, Mellander L, Nishimura N, Schaffer CB, Tsai PS, Kleinfeld D Microcirculation (New York, N.Y. : 1994) 25705966 Microcirculation 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25705966
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Differential Multiphoton Laser Scanning Microscopy. Field JJ, Sheetz KE, Chandler EV, Hoover EE, Young MD, Ding SY, Sylvester AW, Kleinfeld D, Squier JA IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society 27390511 IEEE J Sel Top Quantum Electron 2012 Jan-Feb https://www.ncbi.nlm.nih.gov/pubmed/27390511
Precision mapping of the vibrissa representation within murine primary somatosensory cortex. Knutsen PM, Mateo C, Kleinfeld D Philosophical transactions of the Royal Society of London. Series B, Biological sciences 27574305 Philos Trans R Soc Lond B Biol Sci 2016 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/27574305
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The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. Shih AY, Blinder P, Tsai PS, Friedman B, Stanley G, Lyden PD, Kleinfeld D Nature neuroscience 23242312 Nat Neurosci 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/23242312
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Construction of Cell-based Neurotransmitter Fluorescent Engineered Reporters (CNiFERs) for Optical Detection of Neurotransmitters In Vivo. Lacin E, Muller A, Fernando M, Kleinfeld D, Slesinger PA Journal of visualized experiments : JoVE 27214050 J Vis Exp 2016 May 12 https://www.ncbi.nlm.nih.gov/pubmed/27214050
The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements. Uhlirova H, Kılıç K, Tian P, Sakadžić S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ Jr, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov S, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A Philosophical transactions of the Royal Society of London. Series B, Biological sciences 27574309 Philos Trans R Soc Lond B Biol Sci 2016 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/27574309
All-optical osteotomy to create windows for transcranial imaging in mice. Jeong DC, Tsai PS, Kleinfeld D Optics express 24104230 Opt Express 2013 Oct 7 https://www.ncbi.nlm.nih.gov/pubmed/24104230
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Prospect for feedback guided surgery with ultra-short pulsed laser light. Jeong DC, Tsai PS, Kleinfeld D Current opinion in neurobiology 22088392 Curr Opin Neurobiol 2012 Feb https://www.ncbi.nlm.nih.gov/pubmed/22088392
ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation. Lin JY, Knutsen PM, Muller A, Kleinfeld D, Tsien RY Nature neuroscience 23995068 Nat Neurosci 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/23995068
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The miRNA Regulation of Stem Cells. Huang XA, Lin H Wiley interdisciplinary reviews. Membrane transport and signaling 23024929 Wiley Interdiscip Rev Membr Transp Signal 2012 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/23024929
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A high-resolution whole-genome map of key chromatin modifications in the adult Drosophila melanogaster. Yin H, Sweeney S, Raha D, Snyder M, Lin H PLoS genetics 22194694 PLoS Genet 2011 Dec https://www.ncbi.nlm.nih.gov/pubmed/22194694
The microRNA regulation of stem cells. Huang XA, Lin H Wiley interdisciplinary reviews. Developmental biology 23801669 Wiley Interdiscip Rev Dev Biol 2012 Jan-Feb https://www.ncbi.nlm.nih.gov/pubmed/23801669
Adaptive decoding for brain-machine interfaces through Bayesian parameter updates. Li Z, O'Doherty JE, Lebedev MA, Nicolelis MA Neural computation 21919788 Neural Comput 2011 Dec https://www.ncbi.nlm.nih.gov/pubmed/21919788
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Creating a neuroprosthesis for active tactile exploration of textures. O'Doherty JE, Shokur S, Medina LE, Lebedev MA, Nicolelis MAL Proceedings of the National Academy of Sciences of the United States of America 31591224 Proc Natl Acad Sci U S A 2019 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/31591224
Active tactile exploration using a brain-machine-brain interface. O'Doherty JE, Lebedev MA, Ifft PJ, Zhuang KZ, Shokur S, Bleuler H, Nicolelis MA Nature 21976021 Nature 2011 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/21976021
High-side digitally current controlled biphasic bipolar microstimulator. Hanson TL, Ómarsson B, O'Doherty JE, Peikon ID, Lebedev MA, Nicolelis MA IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society 22328184 IEEE Trans Neural Syst Rehabil Eng 2012 May https://www.ncbi.nlm.nih.gov/pubmed/22328184
Stochastic facilitation of artificial tactile sensation in primates. Medina LE, Lebedev MA, O'Doherty JE, Nicolelis MA The Journal of neuroscience : the official journal of the Society for Neuroscience 23055496 J Neurosci 2012 Oct 10 https://www.ncbi.nlm.nih.gov/pubmed/23055496
Cortical correlates of fitts' law. Ifft PJ, Lebedev MA, Nicolelis MA Frontiers in integrative neuroscience 22275888 Front Integr Neurosci 2011 https://www.ncbi.nlm.nih.gov/pubmed/22275888
Analysis of neuronal ensemble activity reveals the pitfalls and shortcomings of rotation dynamics. Lebedev MA, Ossadtchi A, Mill NA, Urpí NA, Cervera MR, Nicolelis MAL Scientific reports 31831758 Sci Rep 2019 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/31831758
Chronic, wireless recordings of large-scale brain activity in freely moving rhesus monkeys. Schwarz DA, Lebedev MA, Hanson TL, Dimitrov DF, Lehew G, Meloy J, Rajangam S, Subramanian V, Ifft PJ, Li Z, Ramakrishnan A, Tate A, Zhuang KZ, Nicolelis MA Nature methods 24776634 Nat Methods 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24776634
Chronic spinal cord electrical stimulation protects against 6-hydroxydopamine lesions. Yadav AP, Fuentes R, Zhang H, Vinholo T, Wang CH, Freire MA, Nicolelis MA Scientific reports 24452435 Sci Rep 2014 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/24452435
Subcortical neuronal ensembles: an analysis of motor task association, tremor, oscillations, and synchrony in human patients. Hanson TL, Fuller AM, Lebedev MA, Turner DA, Nicolelis MA The Journal of neuroscience : the official journal of the Society for Neuroscience 22723703 J Neurosci 2012 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/22723703
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Virtual active touch using randomly patterned intracortical microstimulation. O'Doherty JE, Lebedev MA, Li Z, Nicolelis MA IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society 22207642 IEEE Trans Neural Syst Rehabil Eng 2012 Jan https://www.ncbi.nlm.nih.gov/pubmed/22207642
Rapamycin-inspired macrocycles with new target specificity. Guo Z, Hong SY, Wang J, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, Coe I, Paavilainen VO, Sun Z, Liu JO Nature chemistry 30532015 Nat Chem 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30532015
A simple and efficient route to the FKBP-binding domain from rapamycin. Li W, Bhat S, Liu JO Tetrahedron letters 21894238 Tetrahedron Lett 2011 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/21894238
Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids. Cambier CJ, Takaki KK, Larson RP, Hernandez RE, Tobin DM, Urdahl KB, Cosma CL, Ramakrishnan L Nature 24336213 Nature 2014 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/24336213
Computer-Assisted Transgenesis of Caenorhabditis elegans for Deep Phenotyping. Gilleland CL, Falls AT, Noraky J, Heiman MG, Yanik MF Genetics 26163188 Genetics 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26163188
Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish. Takaki K, Davis JM, Winglee K, Ramakrishnan L Nature protocols 23680983 Nat Protoc 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23680983
TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. Roca FJ, Ramakrishnan L Cell 23582643 Cell 2013 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/23582643
Combinatorial programming of human neuronal progenitors using magnetically-guided stoichiometric mRNA delivery. Azimi SM, Sheridan SD, Ghannad-Rezaie M, Eimon PM, Yanik MF eLife 29714688 Elife 2018 May 1 https://www.ncbi.nlm.nih.gov/pubmed/29714688
Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs. Adams KN, Szumowski JD, Ramakrishnan L The Journal of infectious diseases 24532601 J Infect Dis 2014 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/24532601
LoCo: a novel main chain scoring function for protein structure prediction based on local coordinates. Moughon SE, Samudrala R BMC bioinformatics 21920038 BMC Bioinformatics 2011 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/21920038
Structure prediction of partial-length protein sequences. Laurenzi A, Hung LH, Samudrala R International journal of molecular sciences 23867606 Int J Mol Sci 2013 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/23867606
Homo-dimerization and ligand binding by the leucine-rich repeat domain at RHG1/RFS2 underlying resistance to two soybean pathogens. Afzal AJ, Srour A, Goil A, Vasudaven S, Liu T, Samudrala R, Dogra N, Kohli P, Malakar A, Lightfoot DA BMC plant biology 23497186 BMC Plant Biol 2013 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/23497186
CANDOCK: Chemical Atomic Network-Based Hierarchical Flexible Docking Algorithm Using Generalized Statistical Potentials. Fine J, Konc J, Samudrala R, Chopra G Journal of chemical information and modeling 32069042 J Chem Inf Model 2020 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/32069042
Optimal COVID-19 therapeutic candidate discovery using the CANDO platform. Mangione W, Falls Z, Samudrala R Frontiers in pharmacology 36091793 Front Pharmacol 2022 https://www.ncbi.nlm.nih.gov/pubmed/36091793
Multiscale modelling of relationships between protein classes and drug behavior across all diseases using the CANDO platform. Sethi G, Chopra G, Samudrala R Mini reviews in medicinal chemistry 25694071 Mini Rev Med Chem 2015 https://www.ncbi.nlm.nih.gov/pubmed/25694071
The Promise and Challenge of Digital Biology. Minie ME, Samudrala R Journal of bioengineering & biomedical science 30338132 J Bioeng Biomed Sci 2013 https://www.ncbi.nlm.nih.gov/pubmed/30338132
Linking Genome and Exposome: Computational Analysis of Human Variation in Chemical-Target Interactions. Bruggemann L, Hawthorne C, Samudrala R, Lopez-Campos GH Studies in health technology and informatics 32570644 Stud Health Technol Inform 2020 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/32570644
Shotgun drug repurposing biotechnology to tackle epidemics and pandemics. Mangione W, Falls Z, Melendy T, Chopra G, Samudrala R Drug discovery today 32405249 Drug Discov Today 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32405249
Accurate Prediction of Inhibitor Binding to HIV-1 Protease Using CANDOCK. Falls Z, Fine J, Chopra G, Samudrala R Frontiers in chemistry 35111726 Front Chem 2021 https://www.ncbi.nlm.nih.gov/pubmed/35111726
Multiscale Analysis and Validation of Effective Drug Combinations Targeting Driver KRAS Mutations in Non-Small Cell Lung Cancer. Bruggemann L, Falls Z, Mangione W, Schwartz SA, Battaglia S, Aalinkeel R, Mahajan SD, Samudrala R International journal of molecular sciences 36674513 Int J Mol Sci 2023 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/36674513
Antiviral Approaches against Influenza Virus. Kumari R, Sharma SD, Kumar A, Ende Z, Mishina M, Wang Y, Falls Z, Samudrala R, Pohl J, Knight PR, Sambhara S Clinical microbiology reviews 36645300 Clin Microbiol Rev 2023 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/36645300
Computational chemoproteomics to understand the role of selected psychoactives in treating mental health indications. Fine J, Lackner R, Samudrala R, Chopra G Scientific reports 31511563 Sci Rep 2019 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/31511563
Computational Grafting of Epitopes. Manish M, Mishra S, Pahuja M, Anand A, Subbarao N, Samudrala R Methods in molecular biology (Clifton, N.J.) 37258909 Methods Mol Biol 2023 https://www.ncbi.nlm.nih.gov/pubmed/37258909
Accurate informatic modeling of tooth enamel pellicle interactions by training substitution matrices with Mat4Pep. Keeper JH, Seto J, Oren EE, Horst OV, Hung LH, Samudrala R Frontiers in materials 40756065 Front Mater 2024 https://www.ncbi.nlm.nih.gov/pubmed/40756065
Self-assembly of filamentous amelogenin requires calcium and phosphate: from dimers via nanoribbons to fibrils. Martinez-Avila O, Wu S, Kim SJ, Cheng Y, Khan F, Samudrala R, Sali A, Horst JA, Habelitz S Biomacromolecules 22974364 Biomacromolecules 2012 Nov 12 https://www.ncbi.nlm.nih.gov/pubmed/22974364
Cementomimetics-constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides. Gungormus M, Oren EE, Horst JA, Fong H, Hnilova M, Somerman MJ, Snead ML, Samudrala R, Tamerler C, Sarikaya M International journal of oral science 22743342 Int J Oral Sci 2012 Jun https://www.ncbi.nlm.nih.gov/pubmed/22743342
Exploring Polypharmacology in Drug Discovery and Repurposing Using the CANDO Platform. Chopra G, Samudrala R Current pharmaceutical design 27013226 Curr Pharm Des 2016 https://www.ncbi.nlm.nih.gov/pubmed/27013226
cando.py: Open Source Software for Predictive Bioanalytics of Large Scale Drug-Protein-Disease Data. Mangione W, Falls Z, Chopra G, Samudrala R Journal of chemical information and modeling 32515949 J Chem Inf Model 2020 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/32515949
Association of C>U RNA Editing with Human Disease Variants. Mandloi S, Falls Z, Deng R, Samudrala R, Elkin PL Studies in health technology and informatics 32570581 Stud Health Technol Inform 2020 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/32570581
Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization. Corrigendum. Bondoc JMG, Gutka HJ, Almutairi MM, Patwell R, Rutter MW, Wolf NM, Samudrala R, Mehboob S, Dementiev A, Abad-Zapatero C, Movahedzadeh F Acta crystallographica. Section F, Structural biology communications 32254053 Acta Crystallogr F Struct Biol Commun 2020 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/32254053
A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex. Chatrikhi R, Feeney CF, Pulvino MJ, Alachouzos G, MacRae AJ, Falls Z, Rai S, Brennessel WW, Jenkins JL, Walter MJ, Graubert TA, Samudrala R, Jurica MS, Frontier AJ, Kielkopf CL Cell chemical biology 33689684 Cell Chem Biol 2021 Aug 19 https://www.ncbi.nlm.nih.gov/pubmed/33689684
Multiscale Virtual Screening Optimization for Shotgun Drug Repurposing Using the CANDO Platform. Hudson ML, Samudrala R Molecules (Basel, Switzerland) 33925237 Molecules 2021 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/33925237
Combating Ebola with Repurposed Therapeutics Using the CANDO Platform. Chopra G, Kaushik S, Elkin PL, Samudrala R Molecules (Basel, Switzerland) 27898018 Molecules 2016 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/27898018
Evaluating the performance of drug-repurposing technologies. Schuler J, Falls Z, Mangione W, Hudson ML, Bruggemann L, Samudrala R Drug discovery today 34400352 Drug Discov Today 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34400352
A Deep-Learning Proteomic-Scale Approach for Drug Design. Overhoff B, Falls Z, Mangione W, Samudrala R Pharmaceuticals (Basel, Switzerland) 34959678 Pharmaceuticals (Basel) 2021 Dec 7 https://www.ncbi.nlm.nih.gov/pubmed/34959678
Proteomic Network Analysis of Bronchoalveolar Lavage Fluid in Ex-Smokers to Discover Implicated Protein Targets and Novel Drug Treatments for Chronic Obstructive Pulmonary Disease. Mammen MJ, Tu C, Morris MC, Richman S, Mangione W, Falls Z, Qu J, Broderick G, Sethi S, Samudrala R Pharmaceuticals (Basel, Switzerland) 35631392 Pharmaceuticals (Basel) 2022 May 1 https://www.ncbi.nlm.nih.gov/pubmed/35631392
Strategies for robust, accurate, and generalizable benchmarking of drug discovery platforms. Van Norden M, Mangione W, Falls Z, Samudrala R Bioinformatics (Oxford, England) 41206130 Bioinformatics 2025 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/41206130
A Systematic Review of Computational Drug Discovery, Development, and Repurposing for Ebola Virus Disease Treatment. Schuler J, Hudson ML, Schwartz D, Samudrala R Molecules (Basel, Switzerland) 29053626 Molecules 2017 Oct 20 https://www.ncbi.nlm.nih.gov/pubmed/29053626
Exploration of interaction scoring criteria in the CANDO platform. Falls Z, Mangione W, Schuler J, Samudrala R BMC research notes 31174591 BMC Res Notes 2019 Jun 7 https://www.ncbi.nlm.nih.gov/pubmed/31174591
Fingerprinting CANDO: Increased Accuracy with Structure- and Ligand-Based Shotgun Drug Repurposing. Schuler J, Samudrala R ACS omega 31656912 ACS Omega 2019 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/31656912
Shotgun drug repurposing biotechnology to tackle epidemics and pandemics. Mangione W, Falls Z, Melendy T, Chopra G, Samudrala R ChemRxiv : the preprint server for chemistry 32511286 ChemRxiv 2020 May 4 https://www.ncbi.nlm.nih.gov/pubmed/32511286
Identifying Protein Features and Pathways Responsible for Toxicity Using Machine Learning and Tox21: Implications for Predictive Toxicology. Moukheiber L, Mangione W, Moukheiber M, Maleki S, Falls Z, Gao M, Samudrala R Molecules (Basel, Switzerland) 35566372 Molecules 2022 May 8 https://www.ncbi.nlm.nih.gov/pubmed/35566372
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function. Palanikumar L, Karpauskaite L, Al-Sayegh M, Chehade I, Alam M, Hassan S, Maity D, Ali L, Kalmouni M, Hunashal Y, Ahmed J, Houhou T, Karapetyan S, Falls Z, Samudrala R, Pasricha R, Esposito G, Afzal AJ, Hamilton AD, Kumar S, Magzoub M Nature communications 34172723 Nat Commun 2021 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/34172723
The impact of nucleosome structure on CRISPR/Cas9 fidelity. Handelmann CR, Tsompana M, Samudrala R, Buck MJ Nucleic acids research 36727449 Nucleic Acids Res 2023 Mar 21 https://www.ncbi.nlm.nih.gov/pubmed/36727449
Strategies for robust, accurate, and generalizable benchmarking of drug discovery platforms. Norden MV, Mangione W, Falls Z, Samudrala R bioRxiv : the preprint server for biology 39764006 bioRxiv 2025 Aug 11 https://www.ncbi.nlm.nih.gov/pubmed/39764006
Uncovering novel therapeutics for schizophrenia: a multitarget approach using the CANDO platform. Hu Y, Elefteriou K, Falls Z, Samudrala R bioRxiv : the preprint server for biology 41676525 bioRxiv 2026 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/41676525
Deciphering bisphenol A (BPA)-elicited osteoarthritis mechanisms through network toxicology and molecular docking, then de novo generation of novel therapeutic candidates. Xu S, Jiang L, Zhang Z, Luo X, Wu W, Wu H, Huang Z, Falls Z, Samudrala R, Tan Z BMC pharmacology & toxicology 41408581 BMC Pharmacol Toxicol 2025 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/41408581
Strategic protein target analysis for developing drugs to stop dental caries. Horst JA, Pieper U, Sali A, Zhan L, Chopra G, Samudrala R, Featherstone JD Advances in dental research 22899687 Adv Dent Res 2012 Sep https://www.ncbi.nlm.nih.gov/pubmed/22899687
Accelerated protein structure comparison using TM-score-GPU. Hung LH, Samudrala R Bioinformatics (Oxford, England) 22718788 Bioinformatics 2012 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/22718788
The enzymatic and metabolic capabilities of early life. Goldman AD, Baross JA, Samudrala R PloS one 22970111 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/22970111
CANDO and the infinite drug discovery frontier. Minie M, Chopra G, Sethi G, Horst J, White G, Roy A, Hatti K, Samudrala R Drug discovery today 24980786 Drug Discov Today 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/24980786
Identifying Protein Features Responsible for Improved Drug Repurposing Accuracies Using the CANDO Platform: Implications for Drug Design. Mangione W, Samudrala R Molecules (Basel, Switzerland) 30621144 Molecules 2019 Jan 4 https://www.ncbi.nlm.nih.gov/pubmed/30621144
Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization. Bondoc JMG, Gutka HJ, Almutairi MM, Patwell R, Rutter MW, Wolf NM, Samudrala R, Mehboob S, Movahedzadeh F Acta crystallographica. Section F, Structural biology communications 31584013 Acta Crystallogr F Struct Biol Commun 2019 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/31584013
A fluorescence-based, gain-of-signal, live cell system to evaluate SARS-CoV-2 main protease inhibition. Dey-Rao R, Smith GR, Timilsina U, Falls Z, Samudrala R, Stavrou S, Melendy T Antiviral research 34626674 Antiviral Res 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34626674
Multiscale analysis and optimal glioma therapeutic candidate discovery using the CANDO platform. Xu S, Mangione W, Van Norden M, Elefteriou K, Hu Y, Falls Z, Samudrala R bioRxiv : the preprint server for biology 40475540 bioRxiv 2025 May 23 https://www.ncbi.nlm.nih.gov/pubmed/40475540
Genetic structure in African populations: implications for human demographic history. Lambert CA, Tishkoff SA Cold Spring Harbor symposia on quantitative biology 20453204 Cold Spring Harb Symp Quant Biol 2009 https://www.ncbi.nlm.nih.gov/pubmed/20453204
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Obesity-susceptibility loci and the tails of the pediatric BMI distribution. Mitchell JA, Hakonarson H, Rebbeck TR, Grant SF Obesity (Silver Spring, Md.) 23408508 Obesity (Silver Spring) 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23408508
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Cysteine dioxygenase is essential for mouse sperm osmoadaptation and male fertility. Asano A, Roman HB, Hirschberger LL, Ushiyama A, Nelson JL, Hinchman MM, Stipanuk MH, Travis AJ The FEBS journal 29604178 FEBS J 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29604178
Anti-Müllerian Hormone in the Domestic Dog during the Anestrus to Oestrous Transition. Nagashima JB, Hansen BS, Songsasen N, Travis AJ, Place NJ Reproduction in domestic animals = Zuchthygiene 26708613 Reprod Domest Anim 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26708613
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Activation of actin-cardiac myosin subfragment 1 MgATPase rate by Ca2+ shows cooperativity intrinsic to the thin filament. Tobacman LS Biochemistry 2950924 Biochemistry 1987 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/2950924
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Phospholipase B is activated in response to sterol removal and stimulates acrosome exocytosis in murine sperm. Asano A, Nelson-Harrington JL, Travis AJ The Journal of biological chemistry 23943622 J Biol Chem 2013 Sep 27 https://www.ncbi.nlm.nih.gov/pubmed/23943622
Use of Tethered Enzymes as a Platform Technology for Rapid Analyte Detection. Cohen R, Lata JP, Lee Y, Hernández JC, Nishimura N, Schaffer CB, Mukai C, Nelson JL, Brangman SA, Agrawal Y, Travis AJ PloS one 26605916 PLoS One 2015 https://www.ncbi.nlm.nih.gov/pubmed/26605916
Characterization of the proteomes associating with three distinct membrane raft sub-types in murine sperm. Asano A, Nelson JL, Zhang S, Travis AJ Proteomics 20815087 Proteomics 2010 Oct https://www.ncbi.nlm.nih.gov/pubmed/20815087
Lipid modulation of calcium flux through CaV2.3 regulates acrosome exocytosis and fertilization. Cohen R, Buttke DE, Asano A, Mukai C, Nelson JL, Ren D, Miller RJ, Cohen-Kutner M, Atlas D, Travis AJ Developmental cell 24525187 Dev Cell 2014 Feb 10 https://www.ncbi.nlm.nih.gov/pubmed/24525187
Regulation of myeloid leukaemia by the cell-fate determinant Musashi. Ito T, Kwon HY, Zimdahl B, Congdon KL, Blum J, Lento WE, Zhao C, Lagoo A, Gerrard G, Foroni L, Goldman J, Goh H, Kim SH, Kim DW, Chuah C, Oehler VG, Radich JP, Jordan CT, Reya T Nature 20639863 Nature 2010 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/20639863
Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia. Kwon HY, Bajaj J, Ito T, Blevins A, Konuma T, Weeks J, Lytle NK, Koechlein CS, Rizzieri D, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T Cell stem cell 26212080 Cell Stem Cell 2015 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/26212080
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Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade. Wu X, Zhang W, Font-Burgada J, Palmer T, Hamil AS, Biswas SK, Poidinger M, Borcherding N, Xie Q, Ellies LG, Lytle NK, Wu LW, Fox RG, Yang J, Dowdy SF, Reya T, Karin M Proceedings of the National Academy of Sciences of the United States of America 25189770 Proc Natl Acad Sci U S A 2014 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/25189770
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Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM Nature genetics 17767158 Nat Genet 2007 Oct https://www.ncbi.nlm.nih.gov/pubmed/17767158
Localization of Islet-1-positive cells in the healthy and infarcted adult murine heart. Weinberger F, Mehrkens D, Friedrich FW, Stubbendorff M, Hua X, Müller JC, Schrepfer S, Evans SM, Carrier L, Eschenhagen T Circulation research 22427341 Circ Res 2012 May 11 https://www.ncbi.nlm.nih.gov/pubmed/22427341
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Laugwitz KL, Moretti A, Lam J, Gruber P, Chen Y, Woodard S, Lin LZ, Cai CL, Lu MM, Reth M, Platoshyn O, Yuan JX, Evans S, Chien KR Nature 15703750 Nature 2005 Feb 10 https://www.ncbi.nlm.nih.gov/pubmed/15703750
T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Cai CL, Zhou W, Yang L, Bu L, Qyang Y, Zhang X, Li X, Rosenfeld MG, Chen J, Evans S Development (Cambridge, England) 15843407 Development 2005 May https://www.ncbi.nlm.nih.gov/pubmed/15843407
Expression of the hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 during mouse heart development. Garcia-Frigola C, Shi Y, Evans SM Gene expression patterns : GEP 14643687 Gene Expr Patterns 2003 Dec https://www.ncbi.nlm.nih.gov/pubmed/14643687
Pinch1 is required for normal development of cranial and cardiac neural crest-derived structures. Liang X, Sun Y, Schneider J, Ding JH, Cheng H, Ye M, Bhattacharya S, Rearden A, Evans S, Chen J Circulation research 17272814 Circ Res 2007 Mar 2 https://www.ncbi.nlm.nih.gov/pubmed/17272814
Expression of Isl1 during mouse development. Zhuang S, Zhang Q, Zhuang T, Evans SM, Liang X, Sun Y Gene expression patterns : GEP 23906961 Gene Expr Patterns 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/23906961
Tissue-Specific Cell Cycle Indicator Reveals Unexpected Findings for Cardiac Myocyte Proliferation. Hirai M, Chen J, Evans SM Circulation research 26472817 Circ Res 2016 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/26472817
Smooth muscle origin of postnatal 2nd CVP is pre-determined in early embryo. Liu Q, Zhang H, Tian X, He L, Huang X, Tan Z, Yan Y, Evans SM, Wythe JD, Zhou B Biochemical and biophysical research communications 26902114 Biochem Biophys Res Commun 2016 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/26902114
Are Perivascular Adipocyte Progenitors Mural Cells or Adventitial Fibroblasts? Guimarães-Camboa N, Evans SM Cell stem cell 28475883 Cell Stem Cell 2017 May 4 https://www.ncbi.nlm.nih.gov/pubmed/28475883
Revisiting Preadolescent Cardiomyocyte Proliferation in Mice. Hirai M, Cattaneo P, Chen J, Evans SM Circulation research 26987912 Circ Res 2016 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/26987912
Infarct Fibroblasts Do Not Derive From Bone Marrow Lineages. Moore-Morris T, Cattaneo P, Guimarães-Camboa N, Bogomolovas J, Cedenilla M, Banerjee I, Ricote M, Kisseleva T, Zhang L, Gu Y, Dalton ND, Peterson KL, Chen J, Pucéat M, Evans SM Circulation research 29269349 Circ Res 2018 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/29269349
Development of the cardiac pacemaker. Liang X, Evans SM, Sun Y Cellular and molecular life sciences : CMLS 27770149 Cell Mol Life Sci 2017 Apr https://www.ncbi.nlm.nih.gov/pubmed/27770149
Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion. van Vliet PP, Lin L, Boogerd CJ, Martin JF, Andelfinger G, Grossfeld PD, Evans SM Developmental biology 28669819 Dev Biol 2017 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/28669819
To activate or not to activate: the existential dilemma of an enhancer. Boogerd CJ, Evans SM Circulation research 23538274 Circ Res 2013 Mar 29 https://www.ncbi.nlm.nih.gov/pubmed/23538274
T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration. Song MR, Shirasaki R, Cai CL, Ruiz EC, Evans SM, Lee SK, Pfaff SL Development (Cambridge, England) 17119020 Development 2006 Dec https://www.ncbi.nlm.nih.gov/pubmed/17119020
Isl1Cre reveals a common Bmp pathway in heart and limb development. Yang L, Cai CL, Lin L, Qyang Y, Chung C, Monteiro RM, Mummery CL, Fishman GI, Cogen A, Evans S Development (Cambridge, England) 16556916 Development 2006 Apr https://www.ncbi.nlm.nih.gov/pubmed/16556916
The contribution of Islet1-expressing splanchnic mesoderm cells to distinct branchiomeric muscles reveals significant heterogeneity in head muscle development. Nathan E, Monovich A, Tirosh-Finkel L, Harrelson Z, Rousso T, Rinon A, Harel I, Evans SM, Tzahor E Development (Cambridge, England) 18184728 Development 2008 Feb https://www.ncbi.nlm.nih.gov/pubmed/18184728
IL-11 is a crucial determinant of cardiovascular fibrosis. Schafer S, Viswanathan S, Widjaja AA, Lim WW, Moreno-Moral A, DeLaughter DM, Ng B, Patone G, Chow K, Khin E, Tan J, Chothani SP, Ye L, Rackham OJL, Ko NSJ, Sahib NE, Pua CJ, Zhen NTG, Xie C, Wang M, Maatz H, Lim S, Saar K, Blachut S, Petretto E, Schmidt S, Putoczki T, Guimarães-Camboa N, Wakimoto H, van Heesch S, Sigmundsson K, Lim SL, Soon JL, Chao VTT, Chua YL, Tan TE, Evans SM, Loh YJ, Jamal MH, Ong KK, Chua KC, Ong BH, Chakaramakkil MJ, Seidman JG, Seidman CE, Hubner N, Sin KYK, Cook SA Nature 29160304 Nature 2017 Dec 7 https://www.ncbi.nlm.nih.gov/pubmed/29160304
Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. Ai D, Liu W, Ma L, Dong F, Lu MF, Wang D, Verzi MP, Cai C, Gage PJ, Evans S, Black BL, Brown NA, Martin JF Developmental biology 16836994 Dev Biol 2006 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/16836994
Retinoic acid signaling regulates sonic hedgehog and bone morphogenetic protein signalings during genital tubercle development. Liu L, Suzuki K, Nakagata N, Mihara K, Matsumaru D, Ogino Y, Yashiro K, Hamada H, Liu Z, Evans SM, Mendelsohn C, Yamada G Birth defects research. Part B, Developmental and reproductive toxicology 22127979 Birth Defects Res B Dev Reprod Toxicol 2012 Feb https://www.ncbi.nlm.nih.gov/pubmed/22127979
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Redox Paradox: Can Hypoxia Heal Ischemic Hearts? Guimarães-Camboa N, Evans SM Developmental cell 27875683 Dev Cell 2016 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/27875683
Cardiac fibroblasts: from development to heart failure. Moore-Morris T, Guimarães-Camboa N, Yutzey KE, Pucéat M, Evans SM Journal of molecular medicine (Berlin, Germany) 26169532 J Mol Med (Berl) 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26169532
Promoter activity and transcript mapping in the regulatory region for genes encoding ribosomal protein S15 and polynucleotide phosphorylase of Escherichia coli. Evans S, Dennis PP Gene 3005122 Gene 1985 https://www.ncbi.nlm.nih.gov/pubmed/3005122
Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Cai CL, Liang X, Shi Y, Chu PH, Pfaff SL, Chen J, Evans S Developmental cell 14667410 Dev Cell 2003 Dec https://www.ncbi.nlm.nih.gov/pubmed/14667410
MicroRNAs in a cardiac loop: progenitor or myocyte? Evans SM, Moretti A, Laugwitz KL Developmental cell 21145492 Dev Cell 2010 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/21145492
Myocardial lineage development. Evans SM, Yelon D, Conlon FL, Kirby ML Circulation research 21148449 Circ Res 2010 Dec 10 https://www.ncbi.nlm.nih.gov/pubmed/21148449
Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos. Itou J, Kawakami H, Quach T, Osterwalder M, Evans SM, Zeller R, Kawakami Y Development (Cambridge, England) 22438573 Development 2012 May https://www.ncbi.nlm.nih.gov/pubmed/22438573
Insights into cardiac conduction system formation provided by HCN4 expression. Liang X, Evans SM, Sun Y Trends in cardiovascular medicine 25442735 Trends Cardiovasc Med 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25442735
HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Guimarães-Camboa N, Stowe J, Aneas I, Sakabe N, Cattaneo P, Henderson L, Kilberg MS, Johnson RS, Chen J, McCulloch AD, Nobrega MA, Evans SM, Zambon AC Developmental cell 26028220 Dev Cell 2015 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/26028220
Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Guimarães-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton ND, Rockenstein E, Masliah E, Peterson KL, Stallcup WB, Chen J, Evans SM Cell stem cell 28111199 Cell Stem Cell 2017 Mar 2 https://www.ncbi.nlm.nih.gov/pubmed/28111199
HCN4 dynamically marks the first heart field and conduction system precursors. Liang X, Wang G, Lin L, Lowe J, Zhang Q, Bu L, Chen Y, Chen J, Sun Y, Evans SM Circulation research 23743334 Circ Res 2013 Aug 2 https://www.ncbi.nlm.nih.gov/pubmed/23743334
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A custody battle for the mind: evidence for extensive imprinting in the brain. Tollkuhn J, Xu X, Shah NM Neuron 20696374 Neuron 2010 Aug 12 https://www.ncbi.nlm.nih.gov/pubmed/20696374
Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. Cavanaugh DJ, Chesler AT, Jackson AC, Sigal YM, Yamanaka H, Grant R, O'Donnell D, Nicoll RA, Shah NM, Julius D, Basbaum AI The Journal of neuroscience : the official journal of the Society for Neuroscience 21451044 J Neurosci 2011 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/21451044
Control of masculinization of the brain and behavior. Wu MV, Shah NM Current opinion in neurobiology 20970320 Curr Opin Neurobiol 2011 Feb https://www.ncbi.nlm.nih.gov/pubmed/20970320
Modular genetic control of sexually dimorphic behaviors. Xu X, Coats JK, Yang CF, Wang A, Ahmed OM, Alvarado M, Izumi T, Shah NM Cell 22304924 Cell 2012 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/22304924
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Balancing repair and tolerance of DNA damage caused by alkylating agents. Fu D, Calvo JA, Samson LD Nature reviews. Cancer 22237395 Nat Rev Cancer 2012 Jan 12 https://www.ncbi.nlm.nih.gov/pubmed/22237395
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Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP. Sample V, DiPilato LM, Yang JH, Ni Q, Saucerman JJ, Zhang J Nature chemical biology 22366721 Nat Chem Biol 2012 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/22366721
How cells process information: quantification of spatiotemporal signaling dynamics. Ganesan A, Zhang J Protein science : a publication of the Protein Society 22573643 Protein Sci 2012 Jul https://www.ncbi.nlm.nih.gov/pubmed/22573643
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Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart. Chakir K, Depry C, Dimaano VL, Zhu WZ, Vanderheyden M, Bartunek J, Abraham TP, Tomaselli GF, Liu SB, Xiang YK, Zhang M, Takimoto E, Dulin N, Xiao RP, Zhang J, Kass DA Science translational medicine 21918105 Sci Transl Med 2011 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/21918105
Luminescent kinase activity biosensors based on a versatile bimolecular switch. Herbst KJ, Allen MD, Zhang J Journal of the American Chemical Society 21438554 J Am Chem Soc 2011 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/21438554
Reporting from the field: genetically encoded fluorescent reporters uncover signaling dynamics in living biological systems. Mehta S, Zhang J Annual review of biochemistry 21495849 Annu Rev Biochem 2011 https://www.ncbi.nlm.nih.gov/pubmed/21495849
Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells. Newman RH, Fosbrink MD, Zhang J Chemical reviews 21456512 Chem Rev 2011 May 11 https://www.ncbi.nlm.nih.gov/pubmed/21456512
Visualization of JNK activity dynamics with a genetically encoded fluorescent biosensor. Fosbrink M, Aye-Han NN, Cheong R, Levchenko A, Zhang J Proceedings of the National Academy of Sciences of the United States of America 20212108 Proc Natl Acad Sci U S A 2010 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/20212108
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Global analysis of phosphorylation networks in humans. Hu J, Rho HS, Newman RH, Hwang W, Neiswinger J, Zhu H, Zhang J, Qian J Biochimica et biophysica acta 23524292 Biochim Biophys Acta 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/23524292
DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees. Foret S, Kucharski R, Pellegrini M, Feng S, Jacobsen SE, Robinson GE, Maleszka R Proceedings of the National Academy of Sciences of the United States of America 22416128 Proc Natl Acad Sci U S A 2012 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/22416128
Molecular determinants of scouting behavior in honey bees. Liang ZS, Nguyen T, Mattila HR, Rodriguez-Zas SL, Seeley TD, Robinson GE Science (New York, N.Y.) 22403390 Science 2012 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/22403390
Comparative brain transcriptomic analyses of scouting across distinct behavioural and ecological contexts in honeybees. Liang ZS, Mattila HR, Rodriguez-Zas SL, Southey BR, Seeley TD, Robinson GE Proceedings. Biological sciences 25355476 Proc Biol Sci 2014 Dec 22 https://www.ncbi.nlm.nih.gov/pubmed/25355476
Aggression is associated with aerobic glycolysis in the honey bee brain(1). Chandrasekaran S, Rittschof CC, Djukovic D, Gu H, Raftery D, Price ND, Robinson GE Genes, brain, and behavior 25640316 Genes Brain Behav 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25640316
RNA interference knockdown of DNA methyl-transferase 3 affects gene alternative splicing in the honey bee. Li-Byarlay H, Li Y, Stroud H, Feng S, Newman TC, Kaneda M, Hou KK, Worley KC, Elsik CG, Wickline SA, Jacobsen SE, Ma J, Robinson GE Proceedings of the National Academy of Sciences of the United States of America 23852726 Proc Natl Acad Sci U S A 2013 Jul 30 https://www.ncbi.nlm.nih.gov/pubmed/23852726
Caste-specific differences in hindgut microbial communities of honey bees (Apis mellifera). Kapheim KM, Rao VD, Yeoman CJ, Wilson BA, White BA, Goldenfeld N, Robinson GE PloS one 25874551 PLoS One 2015 https://www.ncbi.nlm.nih.gov/pubmed/25874551
Brain regions and molecular pathways responding to food reward type and value in honey bees. McNeill MS, Kapheim KM, Brockmann A, McGill TA, Robinson GE Genes, brain, and behavior 26566901 Genes Brain Behav 2016 Mar https://www.ncbi.nlm.nih.gov/pubmed/26566901
Transcriptomic analysis of instinctive and learned reward-related behaviors in honey bees. Naeger NL, Robinson GE The Journal of experimental biology 27852762 J Exp Biol 2016 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/27852762
Understanding the relationship between brain gene expression and social behavior: lessons from the honey bee. Zayed A, Robinson GE Annual review of genetics 22994354 Annu Rev Genet 2012 https://www.ncbi.nlm.nih.gov/pubmed/22994354
Activity-dependent gene expression in honey bee mushroom bodies in response to orientation flight. Lutz CC, Robinson GE The Journal of experimental biology 23678099 J Exp Biol 2013 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/23678099
Genomics: moving behavioural ecology beyond the phenotypic gambit. Rittschof CC, Robinson GE Animal behaviour 24954950 Anim Behav 2014 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/24954950
Genomic features of a bumble bee symbiont reflect its host environment. Martinson VG, Magoc T, Koch H, Salzberg SL, Moran NA Applied and environmental microbiology 24747890 Appl Environ Microbiol 2014 Jul https://www.ncbi.nlm.nih.gov/pubmed/24747890
Insights into the Transcriptional Architecture of Behavioral Plasticity in the Honey Bee Apis mellifera. Khamis AM, Hamilton AR, Medvedeva YA, Alam T, Alam I, Essack M, Umylny B, Jankovic BR, Naeger NL, Suzuki M, Harbers M, Robinson GE, Bajic VB Scientific reports 26073445 Sci Rep 2015 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/26073445
The genomes of two key bumblebee species with primitive eusocial organization. Sadd BM, Barribeau SM, Bloch G, de Graaf DC, Dearden P, Elsik CG, Gadau J, Grimmelikhuijzen CJ, Hasselmann M, Lozier JD, Robertson HM, Smagghe G, Stolle E, Van Vaerenbergh M, Waterhouse RM, Bornberg-Bauer E, Klasberg S, Bennett AK, Câmara F, Guigó R, Hoff K, Mariotti M, Munoz-Torres M, Murphy T, Santesmasses D, Amdam GV, Beckers M, Beye M, Biewer M, Bitondi MM, Blaxter ML, Bourke AF, Brown MJ, Buechel SD, Cameron R, Cappelle K, Carolan JC, Christiaens O, Ciborowski KL, Clarke DF, Colgan TJ, Collins DH, Cridge AG, Dalmay T, Dreier S, du Plessis L, Duncan E, Erler S, Evans J, Falcon T, Flores K, Freitas FC, Fuchikawa T, Gempe T, Hartfelder K, Hauser F, Helbing S, Humann FC, Irvine F, Jermiin LS, Johnson CE, Johnson RM, Jones AK, Kadowaki T, Kidner JH, Koch V, Köhler A, Kraus FB, Lattorff HM, Leask M, Lockett GA, Mallon EB, Antonio DS, Marxer M, Meeus I, Moritz RF, Nair A, Näpflin K, Nissen I, Niu J, Nunes FM, Oakeshott JG, Osborne A, Otte M, Pinheiro DG, Rossié N, Rueppell O, Santos CG, Schmid-Hempel R, Schmitt BD, Schulte C, Simões ZL, Soares MP, Swevers L, Winnebeck EC, Wolschin F, Yu N, Zdobnov EM, Aqrawi PK, Blankenburg KP, Coyle M, Francisco L, Hernandez AG, Holder M, Hudson ME, Jackson L, Jayaseelan J, Joshi V, Kovar C, Lee SL, Mata R, Mathew T, Newsham IF, Ngo R, Okwuonu G, Pham C, Pu LL, Saada N, Santibanez J, Simmons D, Thornton R, Venkat A, Walden KK, Wu YQ, Debyser G, Devreese B, Asher C, Blommaert J, Chipman AD, Chittka L, Fouks B, Liu J, O'Neill MP, Sumner S, Puiu D, Qu J, Salzberg SL, Scherer SE, Muzny DM, Richards S, Robinson GE, Gibbs RA, Schmid-Hempel P, Worley KC Genome biology 25908251 Genome Biol 2015 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/25908251
Meta-analysis of honey bee neurogenomic response links Deformed wing virus type A to precocious behavioral maturation. Traniello IM, Bukhari SA, Kevill J, Ahmed AC, Hamilton AR, Naeger NL, Schroeder DC, Robinson GE Scientific reports 32080242 Sci Rep 2020 Feb 20 https://www.ncbi.nlm.nih.gov/pubmed/32080242
Physiology of reproductive worker honey bees (Apis mellifera): insights for the development of the worker caste. Peso M, Even N, Søvik E, Naeger NL, Robinson GE, Barron AB Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 26715114 J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26715114
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Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. Rizvi SA, Neidt EM, Cui J, Feiger Z, Skau CT, Gardel ML, Kozmin SA, Kovar DR Chemistry & biology 19942139 Chem Biol 2009 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/19942139
A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival. Meikle L, Talos DM, Onda H, Pollizzi K, Rotenberg A, Sahin M, Jensen FE, Kwiatkowski DJ The Journal of neuroscience : the official journal of the Society for Neuroscience 17522300 J Neurosci 2007 May 23 https://www.ncbi.nlm.nih.gov/pubmed/17522300
Gene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis. Theilhaber J, Rakhade SN, Sudhalter J, Kothari N, Klein P, Pollard J, Jensen FE PloS one 24086344 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/24086344
Mammalian target of rapamycin complex 1 activation negatively regulates Polo-like kinase 2-mediated homeostatic compensation following neonatal seizures. Sun H, Kosaras B, Klein PM, Jensen FE Proceedings of the National Academy of Sciences of the United States of America 23479645 Proc Natl Acad Sci U S A 2013 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/23479645
Finding a better drug for epilepsy: antiepileptogenesis targets. Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, Rho JM Epilepsia 23061663 Epilepsia 2012 Nov https://www.ncbi.nlm.nih.gov/pubmed/23061663
Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures. Rakhade SN, Fitzgerald EF, Klein PM, Zhou C, Sun H, Huganir RL, Jensen FE The Journal of neuroscience : the official journal of the Society for Neuroscience 23223299 J Neurosci 2012 Dec 5 https://www.ncbi.nlm.nih.gov/pubmed/23223299
Contribution of axonal orientation to pathway-dependent modulation of excitatory transmission by direct current stimulation in isolated rat hippocampus. Kabakov AY, Muller PA, Pascual-Leone A, Jensen FE, Rotenberg A Journal of neurophysiology 22219028 J Neurophysiol 2012 Apr https://www.ncbi.nlm.nih.gov/pubmed/22219028
Hypoxia-induced neonatal seizures diminish silent synapses and long-term potentiation in hippocampal CA1 neurons. Zhou C, Lippman JJ, Sun H, Jensen FE The Journal of neuroscience : the official journal of the Society for Neuroscience 22171027 J Neurosci 2011 Dec 14 https://www.ncbi.nlm.nih.gov/pubmed/22171027
Strain-specific differences in perinatal rodent oligodendrocyte lineage progression and its correlation with human. Dean JM, Moravec MD, Grafe M, Abend N, Ren J, Gong X, Volpe JJ, Jensen FE, Hohimer AR, Back SA Developmental neuroscience 21865655 Dev Neurosci 2011 https://www.ncbi.nlm.nih.gov/pubmed/21865655
Epilepsy as a spectrum disorder: Implications from novel clinical and basic neuroscience. Jensen FE Epilepsia 21214533 Epilepsia 2011 Jan https://www.ncbi.nlm.nih.gov/pubmed/21214533
Chloride cotransporter NKCC1 inhibitor bumetanide protects against white matter injury in a rodent model of periventricular leukomalacia. Jantzie LL, Hu MY, Park HK, Jackson MC, Yu J, Maxwell JR, Jensen FE Pediatric research 25585037 Pediatr Res 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25585037
AMPA Receptor Dysregulation and Therapeutic Interventions in a Mouse Model of CDKL5 Deficiency Disorder. Yennawar M, White RS, Jensen FE The Journal of neuroscience : the official journal of the Society for Neuroscience 30952813 J Neurosci 2019 Jun 12 https://www.ncbi.nlm.nih.gov/pubmed/30952813
Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia. Jantzie LL, Talos DM, Selip DB, An L, Jackson MC, Folkerth RD, Deng W, Jensen FE Neuron glia biology 22169210 Neuron Glia Biol 2010 Nov https://www.ncbi.nlm.nih.gov/pubmed/22169210
Epilepsy biomarkers. Engel J Jr, Pitkänen A, Loeb JA, Dudek FE, Bertram EH 3rd, Cole AJ, Moshé SL, Wiebe S, Jensen FE, Mody I, Nehlig A, Vezzani A Epilepsia 23909854 Epilepsia 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23909854
Benign rolandic epileptiform discharges are associated with mood and behavior problems. Sarco DP, Boyer K, Lundy-Krigbaum SM, Takeoka M, Jensen F, Gregas M, Waber DP Epilepsy & behavior : E&B 21862414 Epilepsy Behav 2011 Oct https://www.ncbi.nlm.nih.gov/pubmed/21862414
The tower of Babel: survey on concepts and terminology in electrical status epilepticus in sleep and continuous spikes and waves during sleep in North America. Fernández IS, Chapman KE, Peters JM, Kothare SV, Nordli DR Jr, Jensen FE, Berg AT, Loddenkemper T Epilepsia 23163318 Epilepsia 2013 Apr https://www.ncbi.nlm.nih.gov/pubmed/23163318
Epileptogenesis in the immature brain: emerging mechanisms. Rakhade SN, Jensen FE Nature reviews. Neurology 19578345 Nat Rev Neurol 2009 Jul https://www.ncbi.nlm.nih.gov/pubmed/19578345
Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures. Rakhade SN, Zhou C, Aujla PK, Fishman R, Sucher NJ, Jensen FE The Journal of neuroscience : the official journal of the Society for Neuroscience 18685023 J Neurosci 2008 Aug 6 https://www.ncbi.nlm.nih.gov/pubmed/18685023
Association of the small GTPase Rheb with the NMDA receptor subunit NR3A. Sucher NJ, Yu E, Chan SF, Miri M, Lee BJ, Xiao B, Worley PF, Jensen FE Neuro-Signals 21135540 Neurosignals 2010 https://www.ncbi.nlm.nih.gov/pubmed/21135540
Blinders, phenotype, and fashionable genetic analysis: a critical examination of the current state of epilepsy genetic studies. Greenberg DA, Subaran R Epilepsia 21219301 Epilepsia 2011 Jan https://www.ncbi.nlm.nih.gov/pubmed/21219301
Dysregulation of FMRP/mTOR Signaling Cascade in Hypoxic-Ischemic Injury of Premature Human Brain. Lechpammer M, Wintermark P, Merry KM, Jackson MC, Jantzie LL, Jensen FE Journal of child neurology 26239490 J Child Neurol 2016 Mar https://www.ncbi.nlm.nih.gov/pubmed/26239490
Neonatal seizures alter NMDA glutamate receptor GluN2A and 3A subunit expression and function in hippocampal CA1 neurons. Zhou C, Sun H, Klein PM, Jensen FE Frontiers in cellular neuroscience 26441533 Front Cell Neurosci 2015 https://www.ncbi.nlm.nih.gov/pubmed/26441533
Altered development of glutamatergic synapses in layer V pyramidal neurons in NR3A knockout mice. Zhou C, Jensen FE, Sucher NJ Molecular and cellular neurosciences 19782137 Mol Cell Neurosci 2009 Dec https://www.ncbi.nlm.nih.gov/pubmed/19782137
Development of later life spontaneous seizures in a rodent model of hypoxia-induced neonatal seizures. Rakhade SN, Klein PM, Huynh T, Hilario-Gomez C, Kosaras B, Rotenberg A, Jensen FE Epilepsia 21366558 Epilepsia 2011 Apr https://www.ncbi.nlm.nih.gov/pubmed/21366558
The developing oligodendrocyte: key cellular target in brain injury in the premature infant. Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 21382469 Int J Dev Neurosci 2011 Jun https://www.ncbi.nlm.nih.gov/pubmed/21382469
Regional differences in susceptibility to hypoxic-ischemic injury in the preterm brain: exploring the spectrum from white matter loss to selective grey matter injury in a rat model. Selip DB, Jantzie LL, Chang M, Jackson MC, Fitzgerald EC, Boll G, Murphy A, Jensen FE Neurology research international 22530125 Neurol Res Int 2012 https://www.ncbi.nlm.nih.gov/pubmed/22530125
Developmental factors in the pathogenesis of neonatal seizures. Jensen FE Journal of pediatric neurology : JPN 20191097 J Pediatr Neurol 2009 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/20191097
The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway. Talos DM, Sun H, Zhou X, Fitzgerald EC, Jackson MC, Klein PM, Lan VJ, Joseph A, Jensen FE PloS one 22567115 PLoS One 2012 https://www.ncbi.nlm.nih.gov/pubmed/22567115
Perfusion Imaging of Focal Cortical Dysplasia Using Arterial Spin Labeling: Correlation With Histopathological Vascular Density. Wintermark P, Lechpammer M, Warfield SK, Kosaras B, Takeoka M, Poduri A, Madsen JR, Bergin AM, Whalen S, Jensen FE Journal of child neurology 23696629 J Child Neurol 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/23696629
Issues related to development of antiepileptogenic therapies. Pitkänen A, Nehlig A, Brooks-Kayal AR, Dudek FE, Friedman D, Galanopoulou AS, Jensen FE, Kaminski RM, Kapur J, Klitgaard H, Löscher W, Mody I, Schmidt D Epilepsia 23909852 Epilepsia 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23909852
Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy. Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M, Scharfman HE Epilepsia 23909853 Epilepsia 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23909853
Models of hypoxia and ischemia-induced seizures. Sun H, Juul HM, Jensen FE Journal of neuroscience methods 26434705 J Neurosci Methods 2016 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/26434705
Early-life seizures alter synaptic calcium-permeable AMPA receptor function and plasticity. Lippman-Bell JJ, Zhou C, Sun H, Feske JS, Jensen FE Molecular and cellular neurosciences 27521497 Mol Cell Neurosci 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27521497
Subunit composition of glutamate and gamma-aminobutyric acid receptors in status epilepticus. Loddenkemper T, Talos DM, Cleary RT, Joseph A, Sánchez Fernández I, Alexopoulos A, Kotagal P, Najm I, Jensen FE Epilepsy research 24613745 Epilepsy Res 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24613745
Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures. Cleary RT, Sun H, Huynh T, Manning SM, Li Y, Rotenberg A, Talos DM, Kahle KT, Jackson M, Rakhade SN, Berry G, Jensen FE PloS one 23536761 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23536761
Altered hippocampal dendritic spine maturation after hypoxia-induced seizures in neonatal rats. Lippman-Bell JJ, Handy M, Nieder CG, Getzfread M, Jensen FE Molecular and cellular neurosciences 34015497 Mol Cell Neurosci 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34015497
Lestaurtinib (CEP-701) attenuates "second hit" kainic acid-induced seizures following early life hypoxic seizures. Obeid M, Rosenberg EC, Klein PM, Jensen FE Epilepsy research 24582454 Epilepsy Res 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24582454
Developmental expression of N-methyl-D-aspartate (NMDA) receptor subunits in human white and gray matter: potential mechanism of increased vulnerability in the immature brain. Jantzie LL, Talos DM, Jackson MC, Park HK, Graham DA, Lechpammer M, Folkerth RD, Volpe JJ, Jensen FE Cerebral cortex (New York, N.Y. : 1991) 24046081 Cereb Cortex 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/24046081
Antiepileptic effects of levetiracetam in a rodent neonatal seizure model. Talos DM, Chang M, Kosaras B, Fitzgerald E, Murphy A, Folkerth RD, Jensen FE Pediatric research 23138400 Pediatr Res 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/23138400
AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures. Lippman-Bell JJ, Rakhade SN, Klein PM, Obeid M, Jackson MC, Joseph A, Jensen FE Epilepsia 24117347 Epilepsia 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/24117347
Neonatal seizures: an update on mechanisms and management. Jensen FE Clinics in perinatology 19944840 Clin Perinatol 2009 Dec https://www.ncbi.nlm.nih.gov/pubmed/19944840
Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia. Talos DM, Sun H, Kosaras B, Joseph A, Folkerth RD, Poduri A, Madsen JR, Black PM, Jensen FE Annals of neurology 22447678 Ann Neurol 2012 Apr https://www.ncbi.nlm.nih.gov/pubmed/22447678
Does acquired epileptogenesis in the immature brain require neuronal death. Baram TZ, Jensen FE, Brooks-Kayal A Epilepsy currents 21461261 Epilepsy Curr 2011 Jan https://www.ncbi.nlm.nih.gov/pubmed/21461261
The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain. Manning SM, Boll G, Fitzgerald E, Selip DB, Volpe JJ, Jensen FE International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 21624454 Int J Dev Neurosci 2011 Nov https://www.ncbi.nlm.nih.gov/pubmed/21624454
Cannabidiol attenuates seizure susceptibility and behavioural deficits in adult CDKL5(R59X) knock-in mice. Li X, Yennawar M, Wiest A, O'Brien WT, Babrowicz B, White RS, Talos DM, Jensen FE The European journal of neuroscience 38654472 Eur J Neurosci 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38654472
Regulation of seizure-induced MeCP2 Ser421 phosphorylation in the developing brain. Rosenberg EC, Lippman-Bell JJ, Handy M, Soldan SS, Rakhade S, Hilario-Gomez C, Folweiler K, Jacobs L, Jensen FE Neurobiology of disease 29738885 Neurobiol Dis 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29738885
Neural correlates of novelty and face-age effects in young and elderly adults. Wright CI, Negreira A, Gold AL, Britton JC, Williams D, Barrett LF NeuroImage 18586522 Neuroimage 2008 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/18586522
Individual differences in learning the affective value of others under minimal conditions. Bliss-Moreau E, Barrett LF, Wright CI Emotion (Washington, D.C.) 18729580 Emotion 2008 Aug https://www.ncbi.nlm.nih.gov/pubmed/18729580
Novelty as a dimension in the affective brain. Weierich MR, Wright CI, Negreira A, Dickerson BC, Barrett LF NeuroImage 19796697 Neuroimage 2010 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/19796697
Valence focus and self-esteem lability: reacting to hedonic cues in the social environment. Pietromonaco PR, Barrett LF Emotion (Washington, D.C.) 19485618 Emotion 2009 Jun https://www.ncbi.nlm.nih.gov/pubmed/19485618
Experience Sampling Methods: A Modern Idiographic Approach to Personality Research. Conner TS, Tennen H, Fleeson W, Barrett LF Social and personality psychology compass 19898679 Soc Personal Psychol Compass 2009 May 1 https://www.ncbi.nlm.nih.gov/pubmed/19898679
Reconstructing the Past: A Century of Ideas About Emotion in Psychology. Gendron M, Barrett LF Emotion review : journal of the International Society for Research on Emotion 20221412 Emot Rev 2009 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/20221412
Reading chimpanzee faces: evidence for the role of verbal labels in categorical perception of emotion. Fugate JM, Gouzoules H, Barrett LF Emotion (Washington, D.C.) 20677871 Emotion 2010 Aug https://www.ncbi.nlm.nih.gov/pubmed/20677871
Affect as a Psychological Primitive. Barrett LF, Bliss-Moreau E Advances in experimental social psychology 20552040 Adv Exp Soc Psychol 2009 https://www.ncbi.nlm.nih.gov/pubmed/20552040
I Like the Sound of Your Voice: Affective Learning about Vocal Signals. Bliss-Moreau E, Barrett LF, Owren MJ Journal of experimental social psychology 20495619 J Exp Soc Psychol 2010 May 1 https://www.ncbi.nlm.nih.gov/pubmed/20495619
Situating emotional experience. Wilson-Mendenhall CD, Barrett LF, Barsalou LW Frontiers in human neuroscience 24324420 Front Hum Neurosci 2013 https://www.ncbi.nlm.nih.gov/pubmed/24324420
Perceptions of emotion from facial expressions are not culturally universal: evidence from a remote culture. Gendron M, Roberson D, van der Vyver JM, Barrett LF Emotion (Washington, D.C.) 24708506 Emotion 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24708506
Emotion perception, but not affect perception, is impaired with semantic memory loss. Lindquist KA, Gendron M, Barrett LF, Dickerson BC Emotion (Washington, D.C.) 24512242 Emotion 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24512242
"Utilizing" signal detection theory. Lynn SK, Barrett LF Psychological science 25097061 Psychol Sci 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25097061
Authors’ response: what are emotions and how are they created in the brain? Lindquist KA, Wager TD, Bliss-Moreau E, Kober H, Barret LF The Behavioral and brain sciences 22783560 Behav Brain Sci 2012 Jun https://www.ncbi.nlm.nih.gov/pubmed/22783560
Emotions are real. Barrett LF Emotion (Washington, D.C.) 22642358 Emotion 2012 Jun https://www.ncbi.nlm.nih.gov/pubmed/22642358
The brain basis of emotion: a meta-analytic review. Lindquist KA, Wager TD, Kober H, Bliss-Moreau E, Barrett LF The Behavioral and brain sciences 22617651 Behav Brain Sci 2012 Jun https://www.ncbi.nlm.nih.gov/pubmed/22617651
Considering PTSD from the perspective of brain processes: a psychological construction approach. Suvak MK, Barrett LF Journal of traumatic stress 21298725 J Trauma Stress 2011 Feb https://www.ncbi.nlm.nih.gov/pubmed/21298725
Bridging Token Identity Theory and Supervenience Theory Through Psychological Construction. Barrett LF Psychological inquiry 21785534 Psychol Inq 2011 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/21785534
Emotion Generation and Emotion Regulation: One or Two Depends on Your Point of View. Gross JJ, Barrett LF Emotion review : journal of the International Society for Research on Emotion 21479078 Emot Rev 2011 Jan https://www.ncbi.nlm.nih.gov/pubmed/21479078
Words are a context for mental inference. Betz N, Hoemann K, Barrett LF Emotion (Washington, D.C.) 30628815 Emotion 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/30628815
Learning situated emotions. Lebois LAM, Wilson-Mendenhall CD, Simmons WK, Barrett LF, Barsalou LW Neuropsychologia 29330097 Neuropsychologia 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/29330097
The power of predictions: An emerging paradigm for psychological research. Hutchinson JB, Barrett LF Current directions in psychological science 31749520 Curr Dir Psychol Sci 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31749520
Introducing a Face Sort Paradigm to Evaluate Age Differences in Emotion Perception. Hoemann K, Vicaria IM, Gendron M, Stanley JT The journals of gerontology. Series B, Psychological sciences and social sciences 32211791 J Gerontol B Psychol Sci Soc Sci 2021 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/32211791
Emotion words, emotion concepts, and emotional development in children: A constructionist hypothesis. Hoemann K, Xu F, Barrett LF Developmental psychology 31464489 Dev Psychol 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31464489
Functional connectivity dynamics during film viewing reveal common networks for different emotional experiences. Raz G, Touroutoglou A, Wilson-Mendenhall C, Gilam G, Lin T, Gonen T, Jacob Y, Atzil S, Admon R, Bleich-Cohen M, Maron-Katz A, Hendler T, Barrett LF Cognitive, affective & behavioral neuroscience 27142636 Cogn Affect Behav Neurosci 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27142636
Internal valence modulates the speed of object recognition. Panichello MF, Kveraga K, Chaumon M, Bar M, Barrett LF Scientific reports 28336933 Sci Rep 2017 Mar 23 https://www.ncbi.nlm.nih.gov/pubmed/28336933
Establishing the situated features associated with perceived stress. Lebois LA, Hertzog C, Slavich GM, Barrett LF, Barsalou LW Acta psychologica 27288834 Acta Psychol (Amst) 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/27288834
The neural representation of typical and atypical experiences of negative images: comparing fear, disgust and morbid fascination. Oosterwijk S, Lindquist KA, Adebayo M, Barrett LF Social cognitive and affective neuroscience 26180088 Soc Cogn Affect Neurosci 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/26180088
Intrinsic connectivity in the human brain does not reveal networks for 'basic' emotions. Touroutoglou A, Lindquist KA, Dickerson BC, Barrett LF Social cognitive and affective neuroscience 25680990 Soc Cogn Affect Neurosci 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/25680990
Deficits in Face Recognition and Consequent Quality-of-Life Factors in Individuals with Cerebral Visual Impairment. Bauer CM, Manley CE, Ravenscroft J, Cabral H, Dilks DD, Bex PJ Vision (Basel, Switzerland) 36810313 Vision (Basel) 2023 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/36810313
Reduced stereotypicality and spared use of facial expression predictions for social evaluation in autism. Robles M, Ramos-Grille I, Hervás A, Duran-Tauleria E, Galiano-Landeira J, Wormwood JB, Falter-Wagner CM, Chanes L International journal of clinical and health psychology : IJCHP 38426036 Int J Clin Health Psychol 2024 Apr-Jun https://www.ncbi.nlm.nih.gov/pubmed/38426036
Neural evidence that human emotions share core affective properties. Wilson-Mendenhall CD, Barrett LF, Barsalou LW Psychological science 23603916 Psychol Sci 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23603916
Dissociable large-scale networks anchored in the right anterior insula subserve affective experience and attention. Touroutoglou A, Hollenbeck M, Dickerson BC, Feldman Barrett L NeuroImage 22361166 Neuroimage 2012 May 1 https://www.ncbi.nlm.nih.gov/pubmed/22361166
What You Feel Influences What You See: The Role of Affective Feelings in Resolving Binocular Rivalry. Anderson E, Siegel EH, Barrett LF Journal of experimental social psychology 21789027 J Exp Soc Psychol 2011 Jul https://www.ncbi.nlm.nih.gov/pubmed/21789027
States of mind: emotions, body feelings, and thoughts share distributed neural networks. Oosterwijk S, Lindquist KA, Anderson E, Dautoff R, Moriguchi Y, Barrett LF NeuroImage 22677148 Neuroimage 2012 Sep https://www.ncbi.nlm.nih.gov/pubmed/22677148
Trends in ambulatory self-report: the role of momentary experience in psychosomatic medicine. Conner TS, Barrett LF Psychosomatic medicine 22582330 Psychosom Med 2012 May https://www.ncbi.nlm.nih.gov/pubmed/22582330
The relation between valence and arousal in subjective experience. Kuppens P, Tuerlinckx F, Russell JA, Barrett LF Psychological bulletin 23231533 Psychol Bull 2013 Jul https://www.ncbi.nlm.nih.gov/pubmed/23231533
Is there consistency and specificity of autonomic changes during emotional episodes? Guidance from the Conceptual Act Theory and psychophysiology. Quigley KS, Barrett LF Biological psychology 24388802 Biol Psychol 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24388802
The Future of Psychology: Connecting Mind to Brain. Barrett LF Perspectives on psychological science : a journal of the Association for Psychological Science 19844601 Perspect Psychol Sci 2009 Jul https://www.ncbi.nlm.nih.gov/pubmed/19844601
Understanding the Mind by Measuring the Brain: Lessons From Measuring Behavior (Commentary on Vul et al., 2009). Barrett LF Perspectives on psychological science : a journal of the Association for Psychological Science 19672318 Perspect Psychol Sci 2009 May https://www.ncbi.nlm.nih.gov/pubmed/19672318
Variety in emotional life: within-category typicality of emotional experiences is associated with neural activity in large-scale brain networks. Wilson-Mendenhall CD, Barrett LF, Barsalou LW Social cognitive and affective neuroscience 24563528 Soc Cogn Affect Neurosci 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/24563528
Amygdala task-evoked activity and task-free connectivity independently contribute to feelings of arousal. Touroutoglou A, Bickart KC, Barrett LF, Dickerson BC Human brain mapping 24862171 Hum Brain Mapp 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/24862171
Heightened sensitivity to emotional expressions in generalised anxiety disorder, compared to social anxiety disorder, and controls. Bui E, Anderson E, Goetter EM, Campbell AA, Fischer LE, Barrett LF, Simon NM Cognition & emotion 26395075 Cogn Emot 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/26395075
AFFECT AND THE FRAMING EFFECT WITHIN INDIVIDUALS OVER TIME: RISK TAKING IN A DYNAMIC INVESTMENT SIMULATION. Seo MG, Goldfarb B, Barrett LF Academy of Management journal. Academy of Management 26412860 Acad Manage J 2010 Apr https://www.ncbi.nlm.nih.gov/pubmed/26412860
Brain network connectivity-behavioral relationships exhibit trait-like properties: Evidence from hippocampal connectivity and memory. Touroutoglou A, Andreano JM, Barrett LF, Dickerson BC Hippocampus 26105075 Hippocampus 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26105075
Methodological recommendations for a heartbeat detection-based measure of interoceptive sensitivity. Kleckner IR, Wormwood JB, Simmons WK, Barrett LF, Quigley KS Psychophysiology 26265009 Psychophysiology 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26265009
Decision making from economic and signal detection perspectives: development of an integrated framework. Lynn SK, Wormwood JB, Barrett LF, Quigley KS Frontiers in psychology 26217275 Front Psychol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26217275
A Bayesian model of category-specific emotional brain responses. Wager TD, Kang J, Johnson TD, Nichols TE, Satpute AB, Barrett LF PLoS computational biology 25853490 PLoS Comput Biol 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25853490
Involvement of Sensory Regions in Affective Experience: A Meta-Analysis. Satpute AB, Kang J, Bickart KC, Yardley H, Wager TD, Barrett LF Frontiers in psychology 26696928 Front Psychol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26696928
Emotional Granularity is Associated with Daily Experiential Diversity. Hoemann K, Lee Y, Kuppens P, Gendron M, Boyd RL Affective science 37304562 Affect Sci 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/37304562
Amygdala and fusiform gyrus temporal dynamics: responses to negative facial expressions. Britton JC, Shin LM, Barrett LF, Rauch SL, Wright CI BMC neuroscience 18474111 BMC Neurosci 2008 May 12 https://www.ncbi.nlm.nih.gov/pubmed/18474111
She's emotional. He's having a bad day: attributional explanations for emotion stereotypes. Barrett LF, Bliss-Moreau E Emotion (Washington, D.C.) 19803587 Emotion 2009 Oct https://www.ncbi.nlm.nih.gov/pubmed/19803587
Emotional granularity and borderline personality disorder. Suvak MK, Litz BT, Sloan DM, Zanarini MC, Barrett LF, Hofmann SG Journal of abnormal psychology 21171723 J Abnorm Psychol 2011 May https://www.ncbi.nlm.nih.gov/pubmed/21171723
Out of sight but not out of mind: unseen affective faces influence evaluations and social impressions. Anderson E, Siegel E, White D, Barrett LF Emotion (Washington, D.C.) 22506501 Emotion 2012 Dec https://www.ncbi.nlm.nih.gov/pubmed/22506501
Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity. Poulin SP, Dautoff R, Morris JC, Barrett LF, Dickerson BC, Alzheimer's Disease Neuroimaging Initiative Psychiatry research 21920712 Psychiatry Res 2011 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/21920712
The role of affective experience in work motivation: Test of a conceptual model. Seo MG, Bartunek JM, Barrett LF Journal of organizational behavior 21785527 J Organ Behav 2010 Oct https://www.ncbi.nlm.nih.gov/pubmed/21785527
Constructing emotion: the experience of fear as a conceptual act. Lindquist KA, Barrett LF Psychological science 18947355 Psychol Sci 2008 Sep https://www.ncbi.nlm.nih.gov/pubmed/18947355
Functional grouping and cortical-subcortical interactions in emotion: a meta-analysis of neuroimaging studies. Kober H, Barrett LF, Joseph J, Bliss-Moreau E, Lindquist K, Wager TD NeuroImage 18579414 Neuroimage 2008 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/18579414
Context is routinely encoded during emotion perception. Barrett LF, Kensinger EA Psychological science 20424107 Psychol Sci 2010 Apr https://www.ncbi.nlm.nih.gov/pubmed/20424107
Variety is the spice of life: A psychological construction approach to understanding variability in emotion. Barrett LF Cognition & emotion 20221411 Cogn Emot 2009 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/20221411
Intrinsic amygdala-cortical functional connectivity predicts social network size in humans. Bickart KC, Hollenbeck MC, Barrett LF, Dickerson BC The Journal of neuroscience : the official journal of the Society for Neuroscience 23077058 J Neurosci 2012 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/23077058
Affective value and associative processing share a cortical substrate. Shenhav A, Barrett LF, Bar M Cognitive, affective & behavioral neuroscience 23090717 Cogn Affect Behav Neurosci 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23090717
A functional architecture of the human brain: emerging insights from the science of emotion. Lindquist KA, Barrett LF Trends in cognitive sciences 23036719 Trends Cogn Sci 2012 Nov https://www.ncbi.nlm.nih.gov/pubmed/23036719
The hundred-year emotion war: are emotions natural kinds or psychological constructions? Comment on Lench, Flores, and Bench (2011). Lindquist KA, Siegel EH, Quigley KS, Barrett LF Psychological bulletin 23294094 Psychol Bull 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/23294094
Identification of discrete functional subregions of the human periaqueductal gray. Satpute AB, Wager TD, Cohen-Adad J, Bianciardi M, Choi JK, Buhle JT, Wald LL, Barrett LF Proceedings of the National Academy of Sciences of the United States of America 24082116 Proc Natl Acad Sci U S A 2013 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/24082116
Sex differences in the neural correlates of affective experience. Moriguchi Y, Touroutoglou A, Dickerson BC, Barrett LF Social cognitive and affective neuroscience 23596188 Soc Cogn Affect Neurosci 2014 May https://www.ncbi.nlm.nih.gov/pubmed/23596188
Visual predictions in the orbitofrontal cortex rely on associative content. Chaumon M, Kveraga K, Barrett LF, Bar M Cerebral cortex (New York, N.Y. : 1991) 23771980 Cereb Cortex 2014 Nov https://www.ncbi.nlm.nih.gov/pubmed/23771980
Conscious awareness is necessary for affective faces to influence social judgments. Kleckner IR, Anderson EC, Betz NJ, Wormwood JB, Eskew RT Jr, Barrett LF Journal of experimental social psychology 31097841 J Exp Soc Psychol 2018 Nov https://www.ncbi.nlm.nih.gov/pubmed/31097841
Stronger Functional Connectivity in the Default Mode and Salience Networks Is Associated With Youthful Memory in Superaging. Zhang J, Andreano JM, Dickerson BC, Touroutoglou A, Barrett LF Cerebral cortex (New York, N.Y. : 1991) 31058917 Cereb Cortex 2020 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/31058917
Risk Factors, Neuroanatomical Correlates, and Outcome of Neuropsychiatric Symptoms in Alzheimer's Disease. Poulin SP, Bergeron D, Dickerson BC, Alzheimer’s Disease Neuroimaging Initiative Journal of Alzheimer's disease : JAD 28869463 J Alzheimers Dis 2017 https://www.ncbi.nlm.nih.gov/pubmed/28869463
Emotion words: Adding face value. Fugate JMB, Gendron M, Nakashima SF, Barrett LF Emotion (Washington, D.C.) 28604040 Emotion 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/28604040
The Brain Basis of Positive and Negative Affect: Evidence from a Meta-Analysis of the Human Neuroimaging Literature. Lindquist KA, Satpute AB, Wager TD, Weber J, Barrett LF Cerebral cortex (New York, N.Y. : 1991) 25631056 Cereb Cortex 2016 May https://www.ncbi.nlm.nih.gov/pubmed/25631056
Unseen Affective Faces Influence Person Perception Judgments in Schizophrenia. Kring AM, Siegel EH, Barrett LF Clinical psychological science : a journal of the Association for Psychological Science 25664225 Clin Psychol Sci 2014 Jul https://www.ncbi.nlm.nih.gov/pubmed/25664225
Cultural relativity in perceiving emotion from vocalizations. Gendron M, Roberson D, van der Vyver JM, Barrett LF Psychological science 24501109 Psychol Sci 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24501109
Gender moderates the effect of oxytocin on social judgments. Hoge EA, Anderson E, Lawson EA, Bui E, Fischer LE, Khadge SD, Barrett LF, Simon NM Human psychopharmacology 24911580 Hum Psychopharmacol 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24911580
A shift in perspective: Decentering through mindful attention to imagined stressful events. Lebois LA, Papies EK, Gopinath K, Cabanban R, Quigley KS, Krishnamurthy V, Barrett LF, Barsalou LW Neuropsychologia 26111487 Neuropsychologia 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26111487
Threat perception after the Boston Marathon bombings: The effects of personal relevance and conceptual framing. Wormwood JB, Lynn SK, Feldman Barrett L, Quigley KS Cognition & emotion 25707419 Cogn Emot 2016 https://www.ncbi.nlm.nih.gov/pubmed/25707419
Does language do more than communicate emotion? Lindquist KA, Satpute AB, Gendron M Current directions in psychological science 25983400 Curr Dir Psychol Sci 2015 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/25983400
Working memory capacity is associated with optimal adaptation of response bias to perceptual sensitivity in emotion perception. Lynn SK, Ibagon C, Bui E, Palitz SA, Simon NM, Barrett LF Emotion (Washington, D.C.) 26461251 Emotion 2016 Mar https://www.ncbi.nlm.nih.gov/pubmed/26461251
Emotion Words' Effect on Visual Awareness and Attention of Emotional Faces. Fugate JMB, MacDonald C, O'Hare AJ Frontiers in psychology 32010012 Front Psychol 2019 https://www.ncbi.nlm.nih.gov/pubmed/32010012
Gender differences in oxytocin-associated disruption of decision bias during emotion perception. Lynn SK, Hoge EA, Fischer LE, Barrett LF, Simon NM Psychiatry research 24814142 Psychiatry Res 2014 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/24814142
How does this make you feel? A comparison of four affect induction procedures. Zhang X, Yu HW, Barrett LF Frontiers in psychology 25071659 Front Psychol 2014 https://www.ncbi.nlm.nih.gov/pubmed/25071659
Large-scale brain networks in affective and social neuroscience: towards an integrative functional architecture of the brain. Barrett LF, Satpute AB Current opinion in neurobiology 23352202 Curr Opin Neurobiol 2013 Jun https://www.ncbi.nlm.nih.gov/pubmed/23352202
Atrophy in distinct corticolimbic networks in frontotemporal dementia relates to social impairments measured using the Social Impairment Rating Scale. Bickart KC, Brickhouse M, Negreira A, Sapolsky D, Barrett LF, Dickerson BC Journal of neurology, neurosurgery, and psychiatry 24133285 J Neurol Neurosurg Psychiatry 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24133285
Conceptualizing and experiencing compassion. Condon P, Feldman Barrett L Emotion (Washington, D.C.) 23914766 Emotion 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/23914766
Cultural variation in emotion perception is real: a response to Sauter, Eisner, Ekman, and Scott (2015). Gendron M, Roberson D, Barrett LF Psychological science 25608863 Psychol Sci 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25608863
Older and wiser? An affective science perspective on age-related challenges in financial decision making. Weierich MR, Kensinger EA, Munnell AH, Sass SA, Dickerson BC, Wright CI, Barrett LF Social cognitive and affective neuroscience 20587596 Soc Cogn Affect Neurosci 2011 Apr https://www.ncbi.nlm.nih.gov/pubmed/20587596
Differential hemodynamic response in affective circuitry with aging: an FMRI study of novelty, valence, and arousal. Moriguchi Y, Negreira A, Weierich M, Dautoff R, Dickerson BC, Wright CI, Barrett LF Journal of cognitive neuroscience 20521849 J Cogn Neurosci 2011 May https://www.ncbi.nlm.nih.gov/pubmed/20521849
Affective learning enhances activity and functional connectivity in early visual cortex. Damaraju E, Huang YM, Barrett LF, Pessoa L Neuropsychologia 19410587 Neuropsychologia 2009 Oct https://www.ncbi.nlm.nih.gov/pubmed/19410587
See it with feeling: affective predictions during object perception. Barrett LF, Bar M Philosophical transactions of the Royal Society of London. Series B, Biological sciences 19528014 Philos Trans R Soc Lond B Biol Sci 2009 May 12 https://www.ncbi.nlm.nih.gov/pubmed/19528014
Affective state influences perception by affecting decision parameters underlying bias and sensitivity. Lynn SK, Zhang X, Barrett LF Emotion (Washington, D.C.) 22251054 Emotion 2012 Aug https://www.ncbi.nlm.nih.gov/pubmed/22251054
A reliable protocol for the manual segmentation of the human amygdala and its subregions using ultra-high resolution MRI. Entis JJ, Doerga P, Barrett LF, Dickerson BC NeuroImage 22245260 Neuroimage 2012 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/22245260
Emotion words shape emotion percepts. Gendron M, Lindquist KA, Barsalou L, Barrett LF Emotion (Washington, D.C.) 22309717 Emotion 2012 Apr https://www.ncbi.nlm.nih.gov/pubmed/22309717
The visual impact of gossip. Anderson E, Siegel EH, Bliss-Moreau E, Barrett LF Science (New York, N.Y.) 21596956 Science 2011 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/21596956
Amygdala volume and social network size in humans. Bickart KC, Wright CI, Dautoff RJ, Dickerson BC, Barrett LF Nature neuroscience 21186358 Nat Neurosci 2011 Feb https://www.ncbi.nlm.nih.gov/pubmed/21186358
Grounding emotion in situated conceptualization. Wilson-Mendenhall CD, Barrett LF, Simmons WK, Barsalou LW Neuropsychologia 21192959 Neuropsychologia 2011 Apr https://www.ncbi.nlm.nih.gov/pubmed/21192959
Novel response patterns during repeated presentation of affective and neutral stimuli. Satpute AB, Hanington L, Barrett LF Social cognitive and affective neuroscience 27928070 Soc Cogn Affect Neurosci 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27928070
Primary Interoceptive Cortex Activity during Simulated Experiences of the Body. Wilson-Mendenhall CD, Henriques A, Barsalou LW, Barrett LF Journal of cognitive neuroscience 30277431 J Cogn Neurosci 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30277431
Emotion fingerprints or emotion populations? A meta-analytic investigation of autonomic features of emotion categories. Siegel EH, Sands MK, Van den Noortgate W, Condon P, Chang Y, Dy J, Quigley KS, Barrett LF Psychological bulletin 29389177 Psychol Bull 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29389177
Semantic Clustering during Verbal Episodic Memory Encoding and Retrieval in Older Adults: One Cognitive Mechanism of Superaging. Shaffer C, Andreano JM, Touroutoglou A, Barrett LF, Dickerson BC, Wong B Brain sciences 38391745 Brain Sci 2024 Feb 8 https://www.ncbi.nlm.nih.gov/pubmed/38391745
Use of somatic mutations to quantify random contributions to mouse development. Zhou W, Tan Y, Anderson DJ, Crist EM, Ruohola-Baker H, Salipante SJ, Horwitz MS BMC genomics 23327737 BMC Genomics 2013 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/23327737
Passenger mutations as a marker of clonal cell lineages in emerging neoplasia. Salk JJ, Horwitz MS Seminars in cancer biology 20951806 Semin Cancer Biol 2010 Oct https://www.ncbi.nlm.nih.gov/pubmed/20951806
Phylogenetic fate mapping: theoretical and experimental studies applied to the development of mouse fibroblasts. Salipante SJ, Thompson JM, Horwitz MS Genetics 18245843 Genetics 2008 Feb https://www.ncbi.nlm.nih.gov/pubmed/18245843
Phylogenetic analysis of developmental and postnatal mouse cell lineages. Salipante SJ, Kas A, McMonagle E, Horwitz MS Evolution & development 20156285 Evol Dev 2010 Jan-Feb https://www.ncbi.nlm.nih.gov/pubmed/20156285
Clonal expansions in ulcerative colitis identify patients with neoplasia. Salk JJ, Salipante SJ, Risques RA, Crispin DA, Li L, Bronner MP, Brentnall TA, Rabinovitch PS, Horwitz MS, Loeb LA Proceedings of the National Academy of Sciences of the United States of America 19926851 Proc Natl Acad Sci U S A 2009 Dec 8 https://www.ncbi.nlm.nih.gov/pubmed/19926851
Decoding cell lineage from acquired mutations using arbitrary deep sequencing. Carlson CA, Kas A, Kirkwood R, Hays LE, Preston BD, Salipante SJ, Horwitz MS Nature methods 22120468 Nat Methods 2011 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/22120468
Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association. Grotenbreg GM, Nicholson MJ, Fowler KD, Wilbuer K, Octavio L, Yang M, Chakraborty AK, Ploegh HL, Wucherpfennig KW The Journal of biological chemistry 17525157 J Biol Chem 2007 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/17525157
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Comparison study of gold nanohexapods, nanorods, and nanocages for photothermal cancer treatment. Wang Y, Black KC, Luehmann H, Li W, Zhang Y, Cai X, Wan D, Liu SY, Li M, Kim P, Li ZY, Wang LV, Liu Y, Xia Y ACS nano 23383982 ACS Nano 2013 Mar 26 https://www.ncbi.nlm.nih.gov/pubmed/23383982
A bioreducible polymer for efficient delivery of Fas-silencing siRNA into stem cell spheroids and enhanced therapeutic angiogenesis. Shim MS, Bhang SH, Yoon K, Choi K, Xia Y Angewandte Chemie (International ed. in English) 23074025 Angew Chem Int Ed Engl 2012 Nov 19 https://www.ncbi.nlm.nih.gov/pubmed/23074025
Neovascularization in biodegradable inverse opal scaffolds with uniform and precisely controlled pore sizes. Choi SW, Zhang Y, Macewan MR, Xia Y Advanced healthcare materials 23184495 Adv Healthc Mater 2013 Jan https://www.ncbi.nlm.nih.gov/pubmed/23184495
Nanofiber membranes with controllable microwells and structural cues and their use in forming cell microarrays and neuronal networks. Xie J, Liu W, MacEwan MR, Yeh YC, Thomopoulos S, Xia Y Small (Weinheim an der Bergstrasse, Germany) 21294253 Small 2011 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/21294253
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Three-dimensional scaffolds for tissue engineering: the importance of uniformity in pore size and structure. Choi SW, Zhang Y, Xia Y Langmuir : the ACS journal of surfaces and colloids 21090781 Langmuir 2010 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/21090781
Generation of hot spots with silver nanocubes for single-molecule detection by surface-enhanced Raman scattering. Rycenga M, Xia X, Moran CH, Zhou F, Qin D, Li ZY, Xia Y Angewandte Chemie (International ed. in English) 21542081 Angew Chem Int Ed Engl 2011 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/21542081
Au@Ag core-shell nanocubes with finely tuned and well-controlled sizes, shell thicknesses, and optical properties. Ma Y, Li W, Cho EC, Li Z, Yu T, Zeng J, Xie Z, Xia Y ACS nano 20964400 ACS Nano 2010 Nov 23 https://www.ncbi.nlm.nih.gov/pubmed/20964400
A temperature-sensitive drug release system based on phase-change materials. Choi SW, Zhang Y, Xia Y Angewandte Chemie (International ed. in English) 20839209 Angew Chem Int Ed Engl 2010 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/20839209
Seed-mediated synthesis of truncated gold decahedrons with a AuCl/oleylamine complex as precursor. Ma Y, Zeng J, Li W, McKiernan M, Xie Z, Xia Y Advanced materials (Deerfield Beach, Fla.) 20301132 Adv Mater 2010 May 4 https://www.ncbi.nlm.nih.gov/pubmed/20301132
A SERS study of the molecular structure of alkanethiol monolayers on Ag nanocubes in the presence of aqueous glucose. Rycenga M, McLellan JM, Xia Y Chemical physics letters 20160847 Chem Phys Lett 2009 Sep 22 https://www.ncbi.nlm.nih.gov/pubmed/20160847
Stimuli-Responsive Materials for Controlled Release of Theranostic Agents. Wang Y, Shim MS, Levinson NS, Sung HW, Xia Y Advanced functional materials 25477774 Adv Funct Mater 2014 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/25477774
Radiolabeling of Gold Nanocages for Potential Applications in Tracking, Diagnosis, and Image-Guided Therapy. Qiu J, Liu Y, Xia Y Advanced healthcare materials 33470560 Adv Healthc Mater 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/33470560
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SV119-gold nanocage conjugates: a new platform for targeting cancer cells via sigma-2 receptors. Wang Y, Xu J, Xia X, Yang M, Vangveravong S, Chen J, Mach RH, Xia Y Nanoscale 22113350 Nanoscale 2012 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/22113350
Radioluminescent gold nanocages with controlled radioactivity for real-time in vivo imaging. Wang Y, Liu Y, Luehmann H, Xia X, Wan D, Cutler C, Xia Y Nano letters 23360442 Nano Lett 2013 Feb 13 https://www.ncbi.nlm.nih.gov/pubmed/23360442
Investigation of neovascularization in three-dimensional porous scaffolds in vivo by a combination of multiscale photoacoustic microscopy and optical coherence tomography. Cai X, Zhang Y, Li L, Choi SW, MacEwan MR, Yao J, Kim C, Xia Y, Wang LV Tissue engineering. Part C, Methods 22838500 Tissue Eng Part C Methods 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/22838500
Using well-defined Ag nanocubes as substrates to quantify the spatial resolution and penetration depth of surface-enhanced Raman scattering imaging. Moran CH, Rycenga M, Xia X, Cobley CM, Xia Y Nanotechnology 24334508 Nanotechnology 2014 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/24334508
Microscale polymer bottles corked with a phase-change material for temperature-controlled release. Hyun DC, Lu P, Choi SI, Jeong U, Xia Y Angewandte Chemie (International ed. in English) 23959631 Angew Chem Int Ed Engl 2013 Sep 27 https://www.ncbi.nlm.nih.gov/pubmed/23959631
Silica-coated dimers of silver nanospheres as surface-enhanced Raman scattering tags for imaging cancer cells. Xia X, Li W, Zhang Y, Xia Y Interface focus 24427538 Interface Focus 2013 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/24427538
Fabrication of Cell Patches Using Biodegradable Scaffolds with a Hexagonal Array of Interconnected Pores (SHAIPs). Zhang YS, Yao J, Wang LV, Xia Y Polymer 24443593 Polymer (Guildf) 2014 Jan 14 https://www.ncbi.nlm.nih.gov/pubmed/24443593
Neurite outgrowth on electrospun nanofibers with uniaxial alignment: the effects of fiber density, surface coating, and supporting substrate. Xie J, Liu W, MacEwan MR, Bridgman PC, Xia Y ACS nano 24444076 ACS Nano 2014 Feb 25 https://www.ncbi.nlm.nih.gov/pubmed/24444076
Chronic label-free volumetric photoacoustic microscopy of melanoma cells in three-dimensional porous scaffolds. Zhang Y, Cai X, Choi SW, Kim C, Wang LV, Xia Y Biomaterials 20727581 Biomaterials 2010 Nov https://www.ncbi.nlm.nih.gov/pubmed/20727581
Production of Ag nanocubes on a scale of 0.1 g per batch by protecting the NaHS-mediated polyol synthesis with argon. Zhang Q, Cobley C, Au L, McKiernan M, Schwartz A, Wen LP, Chen J, Xia Y ACS applied materials & interfaces 20305725 ACS Appl Mater Interfaces 2009 Sep https://www.ncbi.nlm.nih.gov/pubmed/20305725
Targeting gold nanocages to cancer cells for photothermal destruction and drug delivery. Cobley CM, Au L, Chen J, Xia Y Expert opinion on drug delivery 20345327 Expert Opin Drug Deliv 2010 May https://www.ncbi.nlm.nih.gov/pubmed/20345327
Dissolving Ag from Au-Ag Alloy Nanoboxes with H(2)O(2): A Method for Both Tailoring the Optical Properties and Measuring the H(2)O(2) Concentration. Zhang Q, Cobley CM, Zeng J, Wen LP, Chen J, Xia Y The journal of physical chemistry. C, Nanomaterials and interfaces 20495675 J Phys Chem C Nanomater Interfaces 2010 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/20495675
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Fabrication of Microbeads with a Controllable Hollow Interior and Porous Wall Using a Capillary Fluidic Device. Choi SW, Zhang Y, Xia Y Advanced functional materials 20191106 Adv Funct Mater 2009 Sep 23 https://www.ncbi.nlm.nih.gov/pubmed/20191106
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Nanofiber scaffolds with gradations in mineral content for mimicking the tendon-to-bone insertion site. Li X, Xie J, Lipner J, Yuan X, Thomopoulos S, Xia Y Nano letters 19537737 Nano Lett 2009 Jul https://www.ncbi.nlm.nih.gov/pubmed/19537737
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An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity. Xia X, Yang M, Oetjen LK, Zhang Y, Li Q, Chen J, Xia Y Nanoscale 21225037 Nanoscale 2011 Mar https://www.ncbi.nlm.nih.gov/pubmed/21225037
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In vivo quantitative evaluation of the transport kinetics of gold nanocages in a lymphatic system by noninvasive photoacoustic tomography. Cai X, Li W, Kim CH, Yuan Y, Wang LV, Xia Y ACS nano 22054348 ACS Nano 2011 Dec 27 https://www.ncbi.nlm.nih.gov/pubmed/22054348
Modifying the pores of an inverse opal scaffold with chitosan microstructures for truly three-dimensional cell culture. Zhang Y, Choi SW, Xia Y Macromolecular rapid communications 22231861 Macromol Rapid Commun 2012 Feb 27 https://www.ncbi.nlm.nih.gov/pubmed/22231861
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Dark-field microscopy studies of single metal nanoparticles: understanding the factors that influence the linewidth of the localized surface plasmon resonance. Hu M, Novo C, Funston A, Wang H, Staleva H, Zou S, Mulvaney P, Xia Y, Hartland GV Journal of materials chemistry 18846243 J Mater Chem 2008 https://www.ncbi.nlm.nih.gov/pubmed/18846243
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Understanding the SERS Effects of Single Silver Nanoparticles and Their Dimers, One at a Time. Rycenga M, Camargo PH, Li W, Moran CH, Xia Y The journal of physical chemistry letters 20368749 J Phys Chem Lett 2010 Feb 18 https://www.ncbi.nlm.nih.gov/pubmed/20368749
Bright three-photon luminescence from gold/silver alloyed nanostructures for bioimaging with negligible photothermal toxicity. Tong L, Cobley CM, Chen J, Xia Y, Cheng JX Angewandte Chemie (International ed. in English) 20544899 Angew Chem Int Ed Engl 2010 May 3 https://www.ncbi.nlm.nih.gov/pubmed/20544899
Facile synthesis of Ag nanocubes of 30 to 70 nm in edge length with CF(3)COOAg as a precursor. Zhang Q, Li W, Wen LP, Chen J, Xia Y Chemistry (Weinheim an der Bergstrasse, Germany) 20593441 Chemistry 2010 Sep 3 https://www.ncbi.nlm.nih.gov/pubmed/20593441
Total synthesis of the polycyclic fungal metabolite (+/-)-communesin F. Liu P, Seo JH, Weinreb SM Angewandte Chemie (International ed. in English) 20175174 Angew Chem Int Ed Engl 2010 Mar 8 https://www.ncbi.nlm.nih.gov/pubmed/20175174
Measuring the SERS Enhancement Factors of Dimers with Different Structures Constructed from Silver Nanocubes. Camargo PH, Au L, Rycenga M, Li W, Xia Y Chemical physics letters 20209069 Chem Phys Lett 2010 Jan https://www.ncbi.nlm.nih.gov/pubmed/20209069
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Protein-protected Au clusters as a new class of nanoscale biosensor for label-free fluorescence detection of proteases. Wang Y, Wang Y, Zhou F, Kim P, Xia Y Small (Weinheim an der Bergstrasse, Germany) 22969016 Small 2012 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/22969016
Gold nanocages as contrast agents for photoacoustic imaging. Li W, Brown PK, Wang LV, Xia Y Contrast media & molecular imaging 22025337 Contrast Media Mol Imaging 2011 Sep-Oct https://www.ncbi.nlm.nih.gov/pubmed/22025337
25th anniversary article: galvanic replacement: a simple and versatile route to hollow nanostructures with tunable and well-controlled properties. Xia X, Wang Y, Ruditskiy A, Xia Y Advanced materials (Deerfield Beach, Fla.) 24027074 Adv Mater 2013 Nov 26 https://www.ncbi.nlm.nih.gov/pubmed/24027074
In Vivo Evaluation of Adipose-Derived Stromal Cells Delivered with a Nanofiber Scaffold for Tendon-to-Bone Repair. Lipner J, Shen H, Cavinatto L, Liu W, Havlioglu N, Xia Y, Galatz LM, Thomopoulos S Tissue engineering. Part A 26414599 Tissue Eng Part A 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26414599
Enhancing the Tactile and Near-Infrared Sensing Capabilities of Electrospun PVDF Nanofibers with the Use of Gold Nanocages. Li H, Wu T, Xie M, Shi Y, Shen S, Zhao M, Yang X, Figueroa-Cosme LM, Ke Q, Xia Y Journal of materials chemistry. C 30911394 J Mater Chem C Mater 2018 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/30911394
Multiple facets for extracellular matrix mimicking in regenerative medicine. Zhang YS, Xia Y Nanomedicine (London, England) 25816873 Nanomedicine (Lond) 2015 https://www.ncbi.nlm.nih.gov/pubmed/25816873
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The mechanics of PLGA nanofiber scaffolds with biomimetic gradients in mineral for tendon-to-bone repair. Lipner J, Liu W, Liu Y, Boyle J, Genin GM, Xia Y, Thomopoulos S Journal of the mechanical behavior of biomedical materials 25194525 J Mech Behav Biomed Mater 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25194525
Emerging applications of phase-change materials (PCMs): teaching an old dog new tricks. Hyun DC, Levinson NS, Jeong U, Xia Y Angewandte Chemie (International ed. in English) 24470287 Angew Chem Int Ed Engl 2014 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/24470287
Protein capsules with cross-linked, semipermeable, and enzyme-degradable surface barriers for controlled release. Zhou J, Hyun DC, Liu H, Wu H, Xia Y Macromolecular rapid communications 24957975 Macromol Rapid Commun 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24957975
Using SV119-gold nanocage conjugates to eradicate cancer stem cells through a combination of photothermal and chemo therapies. Sun T, Wang Y, Wang Y, Xu J, Zhao X, Vangveravong S, Mach RH, Xia Y Advanced healthcare materials 24677807 Adv Healthc Mater 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24677807
Nerve guidance conduits based on double-layered scaffolds of electrospun nanofibers for repairing the peripheral nervous system. Xie J, MacEwan MR, Liu W, Jesuraj N, Li X, Hunter D, Xia Y ACS applied materials & interfaces 24806389 ACS Appl Mater Interfaces 2014 Jun 25 https://www.ncbi.nlm.nih.gov/pubmed/24806389
Recent Developments in Shape-Controlled Synthesis of Silver Nanocrystals. Xia X, Zeng J, Zhang Q, Moran CH, Xia Y The journal of physical chemistry. C, Nanomaterials and interfaces 23105955 J Phys Chem C Nanomater Interfaces 2012 https://www.ncbi.nlm.nih.gov/pubmed/23105955
Silver nanocube on gold microplate as a well-defined and highly active substrate for SERS detection. Xia X, Rycenga M, Qin D, Xia Y Journal of materials chemistry. C 24187611 J Mater Chem C Mater 2013 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/24187611
Non-invasive and in situ characterization of the degradation of biomaterial scaffolds by volumetric photoacoustic microscopy. Zhang YS, Cai X, Yao J, Xing W, Wang LV, Xia Y Angewandte Chemie (International ed. in English) 24130155 Angew Chem Int Ed Engl 2014 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/24130155
Measuring the Optical Absorption Cross-sections of Au-Ag Nanocages and Au Nanorods by Photoacoustic Imaging. Cho EC, Kim C, Zhou F, Cobley CM, Song KH, Chen J, Li ZY, Wang LV, Xia Y The journal of physical chemistry. C, Nanomaterials and interfaces 19680423 J Phys Chem C Nanomater Interfaces 2009 May 28 https://www.ncbi.nlm.nih.gov/pubmed/19680423
Probing the surface-enhanced Raman scattering properties of Au-Ag nanocages at two different excitation wavelengths. Rycenga M, Hou KK, Cobley CM, Schwartz AG, Camargo PH, Xia Y Physical chemistry chemical physics : PCCP 19588011 Phys Chem Chem Phys 2009 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/19588011
Fine tuning the optical properties of Au-Ag nanocages by selectively etching Ag with oxygen and a water-soluble thiol. Cho EC, Cobley CM, Rycenga M, Xia Y Journal of materials chemistry 19829745 J Mater Chem 2009 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/19829745
Conductive Core-Sheath Nanofibers and Their Potential Application in Neural Tissue Engineering. Xie J, Macewan MR, Willerth SM, Li X, Moran DW, Sakiyama-Elbert SE, Xia Y Advanced functional materials 19830261 Adv Funct Mater 2009 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/19830261
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In vivo molecular photoacoustic tomography of melanomas targeted by bioconjugated gold nanocages. Kim C, Cho EC, Chen J, Song KH, Au L, Favazza C, Zhang Q, Cobley CM, Gao F, Xia Y, Wang LV ACS nano 20731439 ACS Nano 2010 Aug 24 https://www.ncbi.nlm.nih.gov/pubmed/20731439
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In vitro mineralization by preosteoblasts in poly(DL-lactide-co-glycolide) inverse opal scaffolds reinforced with hydroxyapatite nanoparticles. Choi SW, Zhang Y, Thomopoulos S, Xia Y Langmuir : the ACS journal of surfaces and colloids 20450216 Langmuir 2010 Jul 20 https://www.ncbi.nlm.nih.gov/pubmed/20450216
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Probing the photothermal effect of gold-based nanocages with surface-enhanced Raman scattering (SERS). Rycenga M, Wang Z, Gordon E, Cobley CM, Schwartz AG, Lo CS, Xia Y Angewandte Chemie (International ed. in English) 20014343 Angew Chem Int Ed Engl 2009 https://www.ncbi.nlm.nih.gov/pubmed/20014343
Quantifying the coverage density of poly(ethylene glycol) chains on the surface of gold nanostructures. Xia X, Yang M, Wang Y, Zheng Y, Li Q, Chen J, Xia Y ACS nano 22148912 ACS Nano 2012 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/22148912
Quantitative analysis of the role played by poly(vinylpyrrolidone) in seed-mediated growth of Ag nanocrystals. Xia X, Zeng J, Oetjen LK, Li Q, Xia Y Journal of the American Chemical Society 22206387 J Am Chem Soc 2012 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/22206387
Fabrication of cubic nanocages and nanoframes by dealloying Au/Ag alloy nanoboxes with an aqueous etchant based on Fe(NO3)3 or NH4OH. Lu X, Au L, McLellan J, Li ZY, Marquez M, Xia Y Nano letters 17489641 Nano Lett 2007 Jun https://www.ncbi.nlm.nih.gov/pubmed/17489641
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Spatial transcriptomics for profiling the tropism of viral vectors in tissues. Jang MJ, Coughlin GM, Jackson CR, Chen X, Chuapoco MR, Vendemiatti JL, Wang AZ, Gradinaru V Nature biotechnology 36702899 Nat Biotechnol 2023 Sep https://www.ncbi.nlm.nih.gov/pubmed/36702899
Next-generation hybridization chain reaction tools with enhanced sensitivities to detect challenging targets. Singh C, Bali N, Coughlin GM, Xu J, Polansky JY, Herget U, Gilbert MS, Cammidge T, Spigolon G, Smirnova Y, Gradinaru V, Zinn K, Prober DA bioRxiv : the preprint server for biology 40964373 bioRxiv 2025 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/40964373
Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo. Coughlin GM, Borsos M, Barcelona BH, Appling N, Mayfield AMH, Mackey ED, Eser RA, Jackson CR, Chen X, Kumar SR, Gradinaru V Nature biotechnology 40113953 Nat Biotechnol 2026 Jan https://www.ncbi.nlm.nih.gov/pubmed/40113953
Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity. Mount CW, Yalçın B, Cunliffe-Koehler K, Sundaresh S, Monje M eLife 31625910 Elife 2019 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/31625910
Maladaptive myelination promotes generalized epilepsy progression. Knowles JK, Xu H, Soane C, Batra A, Saucedo T, Frost E, Tam LT, Fraga D, Ni L, Villar K, Talmi S, Huguenard JR, Monje M Nature neuroscience 35501379 Nat Neurosci 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35501379
Neuron-Glial Interactions in Health and Brain Cancer. Pan Y, Monje M Advanced biology 35957525 Adv Biol (Weinh) 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35957525
The neurobiology of long COVID. Monje M, Iwasaki A Neuron 36288726 Neuron 2022 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/36288726
Microenvironmental interactions of oligodendroglial cells. Yalçın B, Monje M Developmental cell 34192527 Dev Cell 2021 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/34192527
Neural Signaling in Cancer. Keough MB, Monje M Annual review of neuroscience 35259916 Annu Rev Neurosci 2022 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/35259916
Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain. Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, Yalçın B, Taylor KR, Dutton S, Acosta-Alvarez L, Ni L, Contreras-Esquivel D, Gehlhausen JR, Klein J, Lucas C, Mao T, Silva J, Peña-Hernández MA, Tabachnikova A, Takahashi T, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Hefti M, Perl D, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M bioRxiv : the preprint server for biology 35043113 bioRxiv 2022 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/35043113
Tumor inflammation-associated neurotoxicity. Mahdi J, Dietrich J, Straathof K, Roddie C, Scott BJ, Davidson TB, Prolo LM, Batchelor TT, Campen CJ, Davis KL, Gust J, Lim M, Majzner RG, Park JR, Partap S, Ramakrishna S, Richards R, Schultz L, Vitanza NA, Wang LD, Mackall CL, Monje M Nature medicine 37024595 Nat Med 2023 Apr https://www.ncbi.nlm.nih.gov/pubmed/37024595
Emerging mechanistic underpinnings and therapeutic targets for chemotherapy-related cognitive impairment. Gibson EM, Monje M Current opinion in oncology 31449084 Curr Opin Oncol 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31449084
Neuron-oligodendroglial interactions in health and malignant disease. Taylor KR, Monje M Nature reviews. Neuroscience 37857838 Nat Rev Neurosci 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37857838
Remote neuronal activity drives glioma progression through SEMA4F. Huang-Hobbs E, Cheng YT, Ko Y, Luna-Figueroa E, Lozzi B, Taylor KR, McDonald M, He P, Chen HC, Yang Y, Maleki E, Lee ZF, Murali S, Williamson MR, Choi D, Curry R, Bayley J, Woo J, Jalali A, Monje M, Noebels JL, Harmanci AS, Rao G, Deneen B Nature 37380778 Nature 2023 Jul https://www.ncbi.nlm.nih.gov/pubmed/37380778
Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis. Savchuk S, Gentry KM, Wang W, Carleton E, Biagi-Junior CAO, Luthria K, Yalçın B, Ni L, Farnsworth HC, Davis RA, Drexler R, Melms JC, Liu Y, Acosta-Alvarez L, Hartmann GG, Pavarino EC, LaBelle J, Woo PJ, Toland AM, Qu F, Kim YS, Filbin MG, Krasnow MA, Ligon KL, Izar B, Sage J, Sabatini BL, Monje M, Venkatesh HS Nature 40931074 Nature 2025 Oct https://www.ncbi.nlm.nih.gov/pubmed/40931074
Myelin plasticity in the ventral tegmental area is required for opioid reward. Yalçın B, Pomrenze MB, Malacon K, Drexler R, Rogers AE, Shamardani K, Chau IJ, Taylor KR, Ni L, Contreras-Esquivel D, Malenka RC, Monje M Nature 38839962 Nature 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38839962
Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling. Drexler R, Drinnenberg A, Gavish A, Yalcin B, Shamardani K, Rogers A, Mancusi R, Taylor KR, Kim YS, Woo PJ, Ravel A, Tatlock E, Ramakrishnan C, Ayala-Sarmiento AE, Pacheco DRF, Siverts L, Daigle TL, Tasic B, Zeng H, Breunig JJ, Deisseroth K, Monje M bioRxiv : the preprint server for biology 39386427 bioRxiv 2024 Sep 24 https://www.ncbi.nlm.nih.gov/pubmed/39386427
Roadmap for the Emerging Field of Cancer Neuroscience. Monje M, Borniger JC, D'Silva NJ, Deneen B, Dirks PB, Fattahi F, Frenette PS, Garzia L, Gutmann DH, Hanahan D, Hervey-Jumper SL, Hondermarck H, Hurov JB, Kepecs A, Knox SM, Lloyd AC, Magnon C, Saloman JL, Segal RA, Sloan EK, Sun X, Taylor MD, Tracey KJ, Trotman LC, Tuveson DA, Wang TC, White RA, Winkler F Cell 32302564 Cell 2020 Apr 16 https://www.ncbi.nlm.nih.gov/pubmed/32302564
NF1 mutation drives neuronal activity-dependent initiation of optic glioma. Pan Y, Hysinger JD, Barron T, Schindler NF, Cobb O, Guo X, Yalçın B, Anastasaki C, Mulinyawe SB, Ponnuswami A, Scheaffer S, Ma Y, Chang KC, Xia X, Toonen JA, Lennon JJ, Gibson EM, Huguenard JR, Liau LM, Goldberg JL, Monje M, Gutmann DH Nature 34040258 Nature 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/34040258
Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State. Nagaraja S, Quezada MA, Gillespie SM, Arzt M, Lennon JJ, Woo PJ, Hovestadt V, Kambhampati M, Filbin MG, Suva ML, Nazarian J, Monje M Molecular cell 31588023 Mol Cell 2019 Dec 19 https://www.ncbi.nlm.nih.gov/pubmed/31588023
Electrical and synaptic integration of glioma into neural circuits. Venkatesh HS, Morishita W, Geraghty AC, Silverbush D, Gillespie SM, Arzt M, Tam LT, Espenel C, Ponnuswami A, Ni L, Woo PJ, Taylor KR, Agarwal A, Regev A, Brang D, Vogel H, Hervey-Jumper S, Bergles DE, Suvà ML, Malenka RC, Monje M Nature 31534222 Nature 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31534222
Remote neuronal activity drives glioma infiltration via Sema4f. Huang-Hobbs E, Cheng YT, Ko Y, Luna-Figueroa E, Lozzi B, Taylor KR, McDonald M, He P, Chen HC, Yang Y, Maleki E, Lee ZF, Murali S, Williamson M, Choi D, Curry R, Bayley J, Woo J, Jalali A, Monje M, Noebels JL, Harmanci AS, Rao G, Deneen B bioRxiv : the preprint server for biology 36993539 bioRxiv 2023 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/36993539
Cancer hallmarks intersect with neuroscience in the tumor microenvironment. Hanahan D, Monje M Cancer cell 36917953 Cancer Cell 2023 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/36917953
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas. Majzner RG, Ramakrishna S, Yeom KW, Patel S, Chinnasamy H, Schultz LM, Richards RM, Jiang L, Barsan V, Mancusi R, Geraghty AC, Good Z, Mochizuki AY, Gillespie SM, Toland AMS, Mahdi J, Reschke A, Nie EH, Chau IJ, Rotiroti MC, Mount CW, Baggott C, Mavroukakis S, Egeler E, Moon J, Erickson C, Green S, Kunicki M, Fujimoto M, Ehlinger Z, Reynolds W, Kurra S, Warren KE, Prabhu S, Vogel H, Rasmussen L, Cornell TT, Partap S, Fisher PG, Campen CJ, Filbin MG, Grant G, Sahaf B, Davis KL, Feldman SA, Mackall CL, Monje M Nature 35130560 Nature 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/35130560
Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability. Drexler R, Khatri R, Sauvigny T, Mohme M, Maire CL, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers AK, Neumann J, Bode H, Hausmann F, Huber TB, Bonn S, Jütten K, Delev D, Weber KJ, Harter PN, Onken J, Vajkoczy P, Capper D, Wiestler B, Weller M, Snijder B, Buck A, Weiss T, Keough MB, Ni L, Monje M, Silverbush D, Hovestadt V, Suvà ML, Krishna S, Hervey-Jumper SL, Schüller U, Heiland DH, Hänzelmann S, Ricklefs FL bioRxiv : the preprint server for biology 37609137 bioRxiv 2023 Aug 7 https://www.ncbi.nlm.nih.gov/pubmed/37609137
Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas. Bredel M, Espinosa L, Kim H, Scholtens DM, McElroy JP, Rajbhandari R, Meng W, Kollmeyer TM, Malta TM, Quezada MA, Harsh GR, Lobo-Jarne T, Solé L, Merati A, Nagaraja S, Nair S, White JJ, Thudi NK, Fleming JL, Webb A, Natsume A, Ogawa S, Weber RG, Bertran J, Haque SJ, Hentschel B, Miller CR, Furnari FB, Chan TA, Grosu AL, Weller M, Barnholtz-Sloan JS, Monje M, Noushmehr H, Jenkins RB, Rogers CL, MacDonald DR, Pugh SL, Chakravarti A Cell reports. Medicine 37343523 Cell Rep Med 2023 Jun 20 https://www.ncbi.nlm.nih.gov/pubmed/37343523
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice. Geraghty AC, Acosta-Alvarez L, Rotiroti M, Dutton S, O'Dea MR, Woo PJ, Xu H, Shamardani K, Mancusi R, Ni L, Mulinyawe SB, Kim WJ, Liddelow SA, Majzner RG, Monje M bioRxiv : the preprint server for biology 38798554 bioRxiv 2024 May 14 https://www.ncbi.nlm.nih.gov/pubmed/38798554
GABAergic neuron-to-glioma synapses in diffuse midline gliomas. Barron T, Yalçın B, Su M, Byun YG, Gavish A, Shamardani K, Xu H, Ni L, Soni N, Mehta V, Maleki Jahan S, Kim YS, Taylor KR, Keough MB, Quezada MA, Geraghty AC, Mancusi R, Vo LT, Castañeda EH, Woo PJ, Petritsch CK, Vogel H, Kaila K, Monje M Nature 39972132 Nature 2025 Mar https://www.ncbi.nlm.nih.gov/pubmed/39972132
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice. Geraghty AC, Acosta-Alvarez L, Rotiroti MC, Dutton S, O'Dea MR, Kim W, Trivedi V, Mancusi R, Shamardani K, Malacon K, Woo PJ, Martinez-Velez N, Pham T, Reche-Ley NN, Otubu G, Castenada EH, Nwangwu K, Xu H, Mulinyawe SB, Zamler DB, Ni L, Cross K, Rustenhoven J, Kipnis J, Liddelow SA, Mackall CL, Majzner RG, Monje M Cell 40359942 Cell 2025 Jun 12 https://www.ncbi.nlm.nih.gov/pubmed/40359942
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling. Drexler R, Drinnenberg A, Gavish A, Yalçin B, Shamardani K, Rogers AE, Mancusi R, Trivedi V, Taylor KR, Kim YS, Woo PJ, Soni N, Su M, Ravel A, Tatlock E, Midler A, Wu SH, Ramakrishnan C, Chen R, Ayala-Sarmiento AE, Fernandez Pacheco DR, Siverts L, Daigle TL, Tasic B, Zeng H, Breunig JJ, Deisseroth K, Monje M Cell 40541184 Cell 2025 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/40541184
Cancer neuroscience: State of the field, emerging directions. Winkler F, Venkatesh HS, Amit M, Batchelor T, Demir IE, Deneen B, Gutmann DH, Hervey-Jumper S, Kuner T, Mabbott D, Platten M, Rolls A, Sloan EK, Wang TC, Wick W, Venkataramani V, Monje M Cell 37059069 Cell 2023 Apr 13 https://www.ncbi.nlm.nih.gov/pubmed/37059069
A prognostic neural epigenetic signature in high-grade glioma. Drexler R, Khatri R, Sauvigny T, Mohme M, Maire CL, Ryba A, Zghaibeh Y, Dührsen L, Salviano-Silva A, Lamszus K, Westphal M, Gempt J, Wefers AK, Neumann JE, Bode H, Hausmann F, Huber TB, Bonn S, Jütten K, Delev D, Weber KJ, Harter PN, Onken J, Vajkoczy P, Capper D, Wiestler B, Weller M, Snijder B, Buck A, Weiss T, Göller PC, Sahm F, Menstel JA, Zimmer DN, Keough MB, Ni L, Monje M, Silverbush D, Hovestadt V, Suvà ML, Krishna S, Hervey-Jumper SL, Schüller U, Heiland DH, Hänzelmann S, Ricklefs FL Nature medicine 38760585 Nat Med 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38760585
Neuroligin-3 interaction with CSPG4 regulates normal and malignant glial precursors through PIEZO1. Gillespie SM, Seok Kim Y, Geraghty AC, Yalçın B, Mancusi R, Hysinger J, English Ivec A, Reed J, Drexler R, Quezada M, Malacon K, Woo P, Mount C, Yang A, Lam M, Pan Y, Bradley Zuchero J, Trotter J, Monje M bioRxiv : the preprint server for biology 40791371 bioRxiv 2025 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/40791371
Microglia in Cancer Therapy-Related Cognitive Impairment. Gibson EM, Monje M Trends in neurosciences 33674135 Trends Neurosci 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33674135
Synaptic Communication in Brain Cancer. Monje M Cancer research 32381657 Cancer Res 2020 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/32381657
The bright and the dark side of myelin plasticity: Neuron-glial interactions in health and disease. Monje M, Káradóttir RT Seminars in cell & developmental biology 33293232 Semin Cell Dev Biol 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/33293232
Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening. Lin GL, Wilson KM, Ceribelli M, Stanton BZ, Woo PJ, Kreimer S, Qin EY, Zhang X, Lennon J, Nagaraja S, Morris PJ, Quezada M, Gillespie SM, Duveau DY, Michalowski AM, Shinn P, Guha R, Ferrer M, Klumpp-Thomas C, Michael S, McKnight C, Minhas P, Itkin Z, Raabe EH, Chen L, Ghanem R, Geraghty AC, Ni L, Andreasson KI, Vitanza NA, Warren KE, Thomas CJ, Monje M Science translational medicine 31748226 Sci Transl Med 2019 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/31748226
Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment. Geraghty AC, Gibson EM, Ghanem RA, Greene JJ, Ocampo A, Goldstein AK, Ni L, Yang T, Marton RM, Paşca SP, Greenberg ME, Longo FM, Monje M Neuron 31122677 Neuron 2019 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/31122677
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1. Mabe NW, Huang M, Dalton GN, Alexe G, Schaefer DA, Geraghty AC, Robichaud AL, Conway AS, Khalid D, Mader MM, Belk JA, Ross KN, Sheffer M, Linde MH, Ly N, Yao W, Rotiroti MC, Smith BAH, Wernig M, Bertozzi CR, Monje M, Mitsiades CS, Majeti R, Satpathy AT, Stegmaier K, Majzner RG Nature cancer 35817829 Nat Cancer 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/35817829
The neuroscience of cancer. Mancusi R, Monje M Nature 37316719 Nature 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/37316719
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location. Liu I, Jiang L, Samuelsson ER, Marco Salas S, Beck A, Hack OA, Jeong D, Shaw ML, Englinger B, LaBelle J, Mire HM, Madlener S, Mayr L, Quezada MA, Trissal M, Panditharatna E, Ernst KJ, Vogelzang J, Gatesman TA, Halbert ME, Palova H, Pokorna P, Sterba J, Slaby O, Geyeregger R, Diaz A, Findlay IJ, Dun MD, Resnick A, Suvà ML, Jones DTW, Agnihotri S, Svedlund J, Koschmann C, Haberler C, Czech T, Slavc I, Cotter JA, Ligon KL, Alexandrescu S, Yung WKA, Arrillaga-Romany I, Gojo J, Monje M, Nilsson M, Filbin MG Nature genetics 36471067 Nat Genet 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36471067
Glioma synapses recruit mechanisms of adaptive plasticity. Taylor KR, Barron T, Hui A, Spitzer A, Yalçin B, Ivec AE, Geraghty AC, Hartmann GG, Arzt M, Gillespie SM, Kim YS, Maleki Jahan S, Zhang H, Shamardani K, Su M, Ni L, Du PP, Woo PJ, Silva-Torres A, Venkatesh HS, Mancusi R, Ponnuswami A, Mulinyawe S, Keough MB, Chau I, Aziz-Bose R, Tirosh I, Suvà ML, Monje M Nature 37914930 Nature 2023 Nov https://www.ncbi.nlm.nih.gov/pubmed/37914930
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice. Pan Y, Hysinger JD, Yalçın B, Lennon JJ, Byun YG, Raghavan P, Schindler NF, Anastasaki C, Chatterjee J, Ni L, Xu H, Malacon K, Jahan SM, Ivec AE, Aghoghovwia BE, Mount CW, Nagaraja S, Scheaffer S, Attardi LD, Gutmann DH, Monje M Nature neuroscience 38816530 Nat Neurosci 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38816530
Dysregulated Microglial Synaptic Engulfment in Diffuse Midline Glioma. Mancusi R, Tatlock E, Shamardani K, Acosta-Alvarez L, Drexler R, Trivedi V, Gavish A, Niizuma K, Soni N, Woo P, Mulinyawe S, Jahan S, Logan N, Malacon K, Byun YG, Geraghty A, Barron T, Taylor K, Monje M bioRxiv : the preprint server for biology 41497590 bioRxiv 2025 Dec 25 https://www.ncbi.nlm.nih.gov/pubmed/41497590
Developmental origins and emerging therapeutic opportunities for childhood cancer. Filbin M, Monje M Nature medicine 30842674 Nat Med 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30842674
Activity Shapes Neural Circuit Form and Function: A Historical Perspective. Pan Y, Monje M The Journal of neuroscience : the official journal of the Society for Neuroscience 31996470 J Neurosci 2020 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/31996470
Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials. Vitanza NA, Monje M Current treatment options in neurology 31290035 Curr Treat Options Neurol 2019 Jul 10 https://www.ncbi.nlm.nih.gov/pubmed/31290035
Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1. Anastasaki C, Mo J, Chen JK, Chatterjee J, Pan Y, Scheaffer SM, Cobb O, Monje M, Le LQ, Gutmann DH Nature communications 35589737 Nat Commun 2022 May 19 https://www.ncbi.nlm.nih.gov/pubmed/35589737
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation. Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, O'Dea MR, Dutton S, Shamardani K, Nwangwu K, Mancusi R, Yalçın B, Taylor KR, Acosta-Alvarez L, Malacon K, Keough MB, Ni L, Woo PJ, Contreras-Esquivel D, Toland AMS, Gehlhausen JR, Klein J, Takahashi T, Silva J, Israelow B, Lucas C, Mao T, Peña-Hernández MA, Tabachnikova A, Homer RJ, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Vogel H, Hefti MM, Perl DP, Liddelow S, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M Cell 35768006 Cell 2022 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/35768006
A light-gated transcriptional recorder for detecting cell-cell contacts. Cho KF, Gillespie SM, Kalogriopoulos NA, Quezada MA, Jacko M, Monje M, Ting AY eLife 35311648 Elife 2022 Mar 21 https://www.ncbi.nlm.nih.gov/pubmed/35311648
Diffuse intrinsic pontine glioma: molecular landscape and emerging therapeutic targets. Aziz-Bose R, Monje M Current opinion in oncology 31464759 Curr Opin Oncol 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31464759
Glioblastoma remodelling of human neural circuits decreases survival. Krishna S, Choudhury A, Keough MB, Seo K, Ni L, Kakaizada S, Lee A, Aabedi A, Popova G, Lipkin B, Cao C, Nava Gonzales C, Sudharshan R, Egladyous A, Almeida N, Zhang Y, Molinaro AM, Venkatesh HS, Daniel AGS, Shamardani K, Hyer J, Chang EF, Findlay A, Phillips JJ, Nagarajan S, Raleigh DR, Brang D, Monje M, Hervey-Jumper SL Nature 37138086 Nature 2023 May https://www.ncbi.nlm.nih.gov/pubmed/37138086
Response to: Elevated L1 expression in ataxia telangiectasia likely explained by an RNA-seq batch effect. Takahashi T, Stoiljkovic M, Song E, Gao XB, Yasumoto Y, Kudo E, Carvalho F, Kong Y, Park A, Shanabrough M, Szigeti-Buck K, Liu ZW, Kristant A, Zhang Y, Sulkowski P, Glazer PM, Kaczmarek LK, Horvath TL, Iwasaki A Neuron 36863323 Neuron 2023 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/36863323
Serotonergic neuron-glioma interactions drive high-grade glioma pathophysiology. Drexler R, Yalçın B, Mancusi R, Rogers A, Shamardani K, Woo PJ, Ravel A, Wu S, Yabo YA, Steger L, de Biagi-Junior CAO, Cascio CL, Malenka R, Heifets BD, Filbin MG, Heiland DH, Deisseroth K, Monje M bioRxiv : the preprint server for biology 41427306 bioRxiv 2025 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/41427306
Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors. Ozkan A, Padmanabhan HK, Shipman SL, Azim E, Kumar P, Sadegh C, Basak AN, Macklis JD eLife 41589677 Elife 2026 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/41589677
Symmetry in levels of axon-axon homophilic adhesion establishes topography in the corpus callosum and development of connectivity between brain hemispheres. Poulopoulos A, Davis P, Brandenburg C, Itoh Y, Galazo MJ, Greig LC, Romanowski AJ, Budnik B, Macklis JD bioRxiv : the preprint server for biology 38585721 bioRxiv 2024 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/38585721
Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons of the cerebral cortex. Veeraraghavan P, Engmann AK, Hatch JJ, Itoh Y, Nguyen D, Addison T, Macklis JD bioRxiv : the preprint server for biology 38328182 bioRxiv 2024 Jan 23 https://www.ncbi.nlm.nih.gov/pubmed/38328182
Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors. Ozkan A, Padmanabhan HK, Shipman SL, Azim E, Kumar P, Sadegh C, Basak AN, Macklis JD bioRxiv : the preprint server for biology 38712174 bioRxiv 2025 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/38712174
Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes. Engmann AK, Hatch JJ, Nanda P, Veeraraghavan P, Ozkan A, Poulopoulos A, Murphy AJ, Macklis JD Nature protocols 35022617 Nat Protoc 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/35022617
Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting. Sahni V, Shnider SJ, Jabaudon D, Song JHT, Itoh Y, Greig LC, Macklis JD Cell reports 34686320 Cell Rep 2021 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/34686320
An evolutionarily acquired microRNA shapes development of mammalian cortical projections. Diaz JL, Siththanandan VB, Lu V, Gonzalez-Nava N, Pasquina L, MacDonald JL, Woodworth MB, Ozkan A, Nair R, He Z, Sahni V, Sarnow P, Palmer TD, Macklis JD, Tharin S Proceedings of the National Academy of Sciences of the United States of America 33139574 Proc Natl Acad Sci U S A 2020 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/33139574
Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Poulopoulos A, Murphy AJ, Ozkan A, Davis P, Hatch J, Kirchner R, Macklis JD Nature 30626971 Nature 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30626971
Cbln1 Directs Axon Targeting by Corticospinal Neurons Specifically toward Thoraco-Lumbar Spinal Cord. Song JHT, Ruven C, Patel P, Ding F, Macklis JD, Sahni V The Journal of neuroscience : the official journal of the Society for Neuroscience 36823038 J Neurosci 2023 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/36823038
Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations. Itoh Y, Sahni V, Shnider SJ, McKee H, Macklis JD Cell reports 36934325 Cell Rep 2023 Mar 28 https://www.ncbi.nlm.nih.gov/pubmed/36934325
Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized cortically differentiating human pluripotent stem cells. Peter M, Shipman S, Macklis JD bioRxiv : the preprint server for biology 37609140 bioRxiv 2023 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/37609140
Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositions. Tran TP, Budnik B, Froberg JE, Macklis JD bioRxiv : the preprint server for biology 39763931 bioRxiv 2025 May 1 https://www.ncbi.nlm.nih.gov/pubmed/39763931
BEAM: A combinatorial recombinase toolbox for binary gene expression and mosaic genetic analysis. Greig LC, Woodworth MB, Poulopoulos A, Lim S, Macklis JD Cell reports 39159043 Cell Rep 2024 Aug 27 https://www.ncbi.nlm.nih.gov/pubmed/39159043
Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized human neural progenitor cells. Peter M, Shipman S, Heo J, Macklis JD iScience 38784012 iScience 2024 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/38784012
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High-precision tumor resection down to few-cell level guided by NIR-IIb molecular fluorescence imaging. Wang F, Qu L, Ren F, Baghdasaryan A, Jiang Y, Hsu R, Liang P, Li J, Zhu G, Ma Z, Dai H Proceedings of the National Academy of Sciences of the United States of America 35380898 Proc Natl Acad Sci U S A 2022 Apr 12 https://www.ncbi.nlm.nih.gov/pubmed/35380898
Cross-Link-Functionalized Nanoparticles for Rapid Excretion in Nanotheranostic Applications. Ma Z, Wang F, Zhong Y, Salazar F, Li J, Zhang M, Ren F, Wu AM, Dai H Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 34334834 Angew Chem Weinheim Bergstr Ger 2020 Nov 9 https://www.ncbi.nlm.nih.gov/pubmed/34334834
Light-sheet microscopy in the near-infrared II window. Wang F, Wan H, Ma Z, Zhong Y, Sun Q, Tian Y, Qu L, Du H, Zhang M, Li L, Ma H, Luo J, Liang Y, Li WJ, Hong G, Liu L, Dai H Nature methods 31086342 Nat Methods 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31086342
Intratumor injected gold molecular clusters for NIR-II imaging and cancer therapy. Baghdasaryan A, Liu H, Ren F, Hsu R, Jiang Y, Wang F, Zhang M, Grigoryan L, Dai H Proceedings of the National Academy of Sciences of the United States of America 38261618 Proc Natl Acad Sci U S A 2024 Jan 30 https://www.ncbi.nlm.nih.gov/pubmed/38261618
Shortwave-infrared-light-emitting probes for the in vivo tracking of cancer vaccines and the elicited immune responses. Ren F, Wang F, Baghdasaryan A, Li Y, Liu H, Hsu R, Wang C, Li J, Zhong Y, Salazar F, Xu C, Jiang Y, Ma Z, Zhu G, Zhao X, Wong KK, Willis R, Christopher Garcia K, Wu A, Mellins E, Dai H Nature biomedical engineering 37620621 Nat Biomed Eng 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/37620621
A SARS-CoV-2 vaccine on an NIR-II/SWIR emitting nanoparticle platform. Jiang Y, Sanyal M, Hussein NA, Baghdasaryan A, Zhang M, Wang F, Ren F, Li J, Zhu G, Meng Y, Adamska JZ, Mellins E, Dai H Science advances 39919189 Sci Adv 2025 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/39919189
Molecular Gold Nanoclusters for Advanced NIR-II Bioimaging and Therapy. Baghdasaryan A, Dai H Chemical reviews 40435324 Chem Rev 2025 Jun 11 https://www.ncbi.nlm.nih.gov/pubmed/40435324
Live imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophore. Feng Y, Zhu S, Antaris AL, Chen H, Xiao Y, Lu X, Jiang L, Diao S, Yu K, Wang Y, Herraiz S, Yue J, Hong X, Hong G, Cheng Z, Dai H, Hsueh AJ Chemical science 28626555 Chem Sci 2017 May 1 https://www.ncbi.nlm.nih.gov/pubmed/28626555
A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging. Antaris AL, Chen H, Diao S, Ma Z, Zhang Z, Zhu S, Wang J, Lozano AX, Fan Q, Chew L, Zhu M, Cheng K, Hong X, Dai H, Cheng Z Nature communications 28524850 Nat Commun 2017 May 19 https://www.ncbi.nlm.nih.gov/pubmed/28524850
Bright quantum dots emitting at ∼1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging. Zhang M, Yue J, Cui R, Ma Z, Wan H, Wang F, Zhu S, Zhou Y, Kuang Y, Zhong Y, Pang DW, Dai H Proceedings of the National Academy of Sciences of the United States of America 29891702 Proc Natl Acad Sci U S A 2018 Jun 26 https://www.ncbi.nlm.nih.gov/pubmed/29891702
Molecular Cancer Imaging in the Second Near-Infrared Window Using a Renal-Excreted NIR-II Fluorophore-Peptide Probe. Wang W, Ma Z, Zhu S, Wan H, Yue J, Ma H, Ma R, Yang Q, Wang Z, Li Q, Qian Y, Yue C, Wang Y, Fan L, Zhong Y, Zhou Y, Gao H, Ruan J, Hu Z, Liang Y, Dai H Advanced materials (Deerfield Beach, Fla.) 29682821 Adv Mater 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29682821
In vivo molecular imaging for immunotherapy using ultra-bright near-infrared-IIb rare-earth nanoparticles. Zhong Y, Ma Z, Wang F, Wang X, Yang Y, Liu Y, Zhao X, Li J, Du H, Zhang M, Cui Q, Zhu S, Sun Q, Wan H, Tian Y, Liu Q, Wang W, Garcia KC, Dai H Nature biotechnology 31570897 Nat Biotechnol 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31570897
Near-Infrared IIb Fluorescence Imaging of Vascular Regeneration with Dynamic Tissue Perfusion Measurement and High Spatial Resolution. Ma Z, Zhang M, Yue J, Alcazar C, Zhong Y, Doyle TC, Dai H, Huang NF Advanced functional materials 31327961 Adv Funct Mater 2018 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/31327961
In vivo non-invasive confocal fluorescence imaging beyond 1,700 nm using superconducting nanowire single-photon detectors. Wang F, Ren F, Ma Z, Qu L, Gourgues R, Xu C, Baghdasaryan A, Li J, Zadeh IE, Los JWN, Fognini A, Qin-Dregely J, Dai H Nature nanotechnology 35606441 Nat Nanotechnol 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35606441
Near-Infrared-II Molecular Dyes for Cancer Imaging and Surgery. Zhu S, Tian R, Antaris AL, Chen X, Dai H Advanced materials (Deerfield Beach, Fla.) 31025403 Adv Mater 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31025403
Phosphorylcholine-conjugated gold-molecular clusters improve signal for Lymph Node NIR-II fluorescence imaging in preclinical cancer models. Baghdasaryan A, Wang F, Ren F, Ma Z, Li J, Zhou X, Grigoryan L, Xu C, Dai H Nature communications 36153336 Nat Commun 2022 Sep 24 https://www.ncbi.nlm.nih.gov/pubmed/36153336
In vivo NIR-II structured-illumination light-sheet microscopy. Wang F, Ma Z, Zhong Y, Salazar F, Xu C, Ren F, Qu L, Wu AM, Dai H Proceedings of the National Academy of Sciences of the United States of America 33526701 Proc Natl Acad Sci U S A 2021 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/33526701
A mini-review on rare-earth down-conversion nanoparticles for NIR-II imaging of biological systems. Zhong Y, Dai H Nano research 34336144 Nano Res 2020 May https://www.ncbi.nlm.nih.gov/pubmed/34336144
Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model. Angelbello AJ, Rzuczek SG, Mckee KK, Chen JL, Olafson H, Cameron MD, Moss WN, Wang ET, Disney MD Proceedings of the National Academy of Sciences of the United States of America 30926669 Proc Natl Acad Sci U S A 2019 Apr 16 https://www.ncbi.nlm.nih.gov/pubmed/30926669
Small molecule targeting of RNA structures in neurological disorders. Angelbello AJ, Chen JL, Disney MD Annals of the New York Academy of Sciences 30964958 Ann N Y Acad Sci 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/30964958
Methods to identify and optimize small molecules interacting with RNA (SMIRNAs). Ursu A, Vézina-Dawod S, Disney MD Drug discovery today 31356880 Drug Discov Today 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31356880
Rational Design of Small Molecules Targeting Oncogenic Noncoding RNAs from Sequence. Disney MD, Angelbello AJ Accounts of chemical research 27993012 Acc Chem Res 2016 Dec 20 https://www.ncbi.nlm.nih.gov/pubmed/27993012
The Hairpin Form of r(G(4)C(2))(exp) in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules. Wang ZF, Ursu A, Childs-Disney JL, Guertler R, Yang WY, Bernat V, Rzuczek SG, Fuerst R, Zhang YJ, Gendron TF, Yildirim I, Dwyer BG, Rice JE, Petrucelli L, Disney MD Cell chemical biology 30503283 Cell Chem Biol 2019 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/30503283
Optimization of the Linker Domain in a Dimeric Compound that Degrades an r(CUG) Repeat Expansion in Cells. Benhamou RI, Abe M, Choudhary S, Meyer SM, Angelbello AJ, Disney MD Journal of medicinal chemistry 32657583 J Med Chem 2020 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/32657583
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer. Costales MG, Aikawa H, Li Y, Childs-Disney JL, Abegg D, Hoch DG, Pradeep Velagapudi S, Nakai Y, Khan T, Wang KW, Yildirim I, Adibekian A, Wang ET, Disney MD Proceedings of the National Academy of Sciences of the United States of America 31964809 Proc Natl Acad Sci U S A 2020 Feb 4 https://www.ncbi.nlm.nih.gov/pubmed/31964809
A Toxic RNA Catalyzes the Cellular Synthesis of Its Own Inhibitor, Shunting It to Endogenous Decay Pathways. Benhamou RI, Angelbello AJ, Wang ET, Disney MD Cell chemical biology 31981476 Cell Chem Biol 2020 Feb 20 https://www.ncbi.nlm.nih.gov/pubmed/31981476
Progress toward the development of the small molecule equivalent of small interfering RNA. Disney MD, Suresh BM, Benhamou RI, Childs-Disney JL Current opinion in chemical biology 32036231 Curr Opin Chem Biol 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32036231
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. Chen JL, Zhang P, Abe M, Aikawa H, Zhang L, Frank AJ, Zembryski T, Hubbs C, Park H, Withka J, Steppan C, Rogers L, Cabral S, Pettersson M, Wager TT, Fountain MA, Rumbaugh G, Childs-Disney JL, Disney MD Journal of the American Chemical Society 32364710 J Am Chem Soc 2020 May 13 https://www.ncbi.nlm.nih.gov/pubmed/32364710
Fragment-Based Approaches to Identify RNA Binders. Suresh BM, Taghavi A, Childs-Disney JL, Disney MD Journal of medicinal chemistry 37186875 J Med Chem 2023 May 25 https://www.ncbi.nlm.nih.gov/pubmed/37186875
Small molecule alteration of RNA sequence in cells and animals. Guan L, Luo Y, Ja WW, Disney MD Bioorganic & medicinal chemistry letters 29079470 Bioorg Med Chem Lett 2018 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/29079470
Development of pharmacophore models for small molecules targeting RNA: Application to the RNA repeat expansion in myotonic dystrophy type 1. Angelbello AJ, González ÀL, Rzuczek SG, Disney MD Bioorganic & medicinal chemistry letters 27839685 Bioorg Med Chem Lett 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27839685
Precise small-molecule recognition of a toxic CUG RNA repeat expansion. Rzuczek SG, Colgan LA, Nakai Y, Cameron MD, Furling D, Yasuda R, Disney MD Nature chemical biology 27941760 Nat Chem Biol 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/27941760
Using Genome Sequence to Enable the Design of Medicines and Chemical Probes. Angelbello AJ, Chen JL, Childs-Disney JL, Zhang P, Wang ZF, Disney MD Chemical reviews 29322778 Chem Rev 2018 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/29322778
Structure-Specific Cleavage of an RNA Repeat Expansion with a Dimeric Small Molecule Is Advantageous over Sequence-Specific Recognition by an Oligonucleotide. Benhamou RI, Angelbello AJ, Andrews RJ, Wang ET, Moss WN, Disney MD ACS chemical biology 31927948 ACS Chem Biol 2020 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/31927948
A Toxic RNA Templates the Synthesis of Its Own Fluorogenic Inhibitor by Using a Bio-orthogonal Tetrazine Ligation in Cells and Tissues. Angelbello AJ, Disney MD ACS chemical biology 32551539 ACS Chem Biol 2020 Jul 17 https://www.ncbi.nlm.nih.gov/pubmed/32551539
Drugging the RNA World. Disney MD, Dwyer BG, Childs-Disney JL Cold Spring Harbor perspectives in biology 30385607 Cold Spring Harb Perspect Biol 2018 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/30385607
Small Molecule Recognition and Tools to Study Modulation of r(CGG)(exp) in Fragile X-Associated Tremor Ataxia Syndrome. Yang WY, He F, Strack RL, Oh SY, Frazer M, Jaffrey SR, Todd PK, Disney MD ACS chemical biology 27276216 ACS Chem Biol 2016 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/27276216
Targeting RNA with Small Molecules To Capture Opportunities at the Intersection of Chemistry, Biology, and Medicine. Disney MD Journal of the American Chemical Society 30896935 J Am Chem Soc 2019 May 1 https://www.ncbi.nlm.nih.gov/pubmed/30896935
Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10. Yang WY, Gao R, Southern M, Sarkar PS, Disney MD Nature communications 27248057 Nat Commun 2016 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/27248057
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Gendron TF, Chew J, Stankowski JN, Hayes LR, Zhang YJ, Prudencio M, Carlomagno Y, Daughrity LM, Jansen-West K, Perkerson EA, O'Raw A, Cook C, Pregent L, Belzil V, van Blitterswijk M, Tabassian LJ, Lee CW, Yue M, Tong J, Song Y, Castanedes-Casey M, Rousseau L, Phillips V, Dickson DW, Rademakers R, Fryer JD, Rush BK, Pedraza O, Caputo AM, Desaro P, Palmucci C, Robertson A, Heckman MG, Diehl NN, Wiggs E, Tierney M, Braun L, Farren J, Lacomis D, Ladha S, Fournier CN, McCluskey LF, Elman LB, Toledo JB, McBride JD, Tiloca C, Morelli C, Poletti B, Solca F, Prelle A, Wuu J, Jockel-Balsarotti J, Rigo F, Ambrose C, Datta A, Yang W, Raitcheva D, Antognetti G, McCampbell A, Van Swieten JC, Miller BL, Boxer AL, Brown RH, Bowser R, Miller TM, Trojanowski JQ, Grossman M, Berry JD, Hu WT, Ratti A, Traynor BJ, Disney MD, Benatar M, Silani V, Glass JD, Floeter MK, Rothstein JD, Boylan KB, Petrucelli L Science translational medicine 28356511 Sci Transl Med 2017 Mar 29 https://www.ncbi.nlm.nih.gov/pubmed/28356511
Gini Coefficients as a Single Value Metric to Define Chemical Probe Selectivity. Ursu A, Childs-Disney JL, Angelbello AJ, Costales MG, Meyer SM, Disney MD ACS chemical biology 32568503 ACS Chem Biol 2020 Aug 21 https://www.ncbi.nlm.nih.gov/pubmed/32568503
How We Think about Targeting RNA with Small Molecules. Costales MG, Childs-Disney JL, Haniff HS, Disney MD Journal of medicinal chemistry 32212706 J Med Chem 2020 Sep 10 https://www.ncbi.nlm.nih.gov/pubmed/32212706
Target-Directed Approaches for Screening Small Molecules against RNA Targets. Haniff HS, Knerr L, Chen JL, Disney MD, Lightfoot HL SLAS discovery : advancing life sciences R & D 32419578 SLAS Discov 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32419578
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera. Tong Y, Zhang P, Yang X, Liu X, Zhang J, Grudniewska M, Jung I, Abegg D, Liu J, Childs-Disney JL, Gibaut QMR, Haniff HS, Adibekian A, Mouradian MM, Disney MD Proceedings of the National Academy of Sciences of the United States of America 38181056 Proc Natl Acad Sci U S A 2024 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/38181056
Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTD. Ursu A, Wang KW, Bush JA, Choudhary S, Chen JL, Baisden JT, Zhang YJ, Gendron TF, Petrucelli L, Yildirim I, Disney MD ACS chemical biology 33196168 ACS Chem Biol 2020 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/33196168
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G(4)C(2))(exp) in c9ALS/FTD via the nuclear RNA exosome. Bush JA, Meyer SM, Fuerst R, Tong Y, Li Y, Benhamou RI, Aikawa H, Zanon PRA, Gibaut QMR, Angelbello AJ, Gendron TF, Zhang YJ, Petrucelli L, Heick Jensen T, Childs-Disney JL, Disney MD Proceedings of the National Academy of Sciences of the United States of America 36409902 Proc Natl Acad Sci U S A 2022 Nov 29 https://www.ncbi.nlm.nih.gov/pubmed/36409902
Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1. Chen JL, VanEtten DM, Fountain MA, Yildirim I, Disney MD Biochemistry 28617590 Biochemistry 2017 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/28617590
Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy. Rzuczek SG, Southern MR, Disney MD ACS chemical biology 26414664 ACS Chem Biol 2015 Dec 18 https://www.ncbi.nlm.nih.gov/pubmed/26414664
Targeted Degradation of a Hypoxia-Associated Non-coding RNA Enhances the Selectivity of a Small Molecule Interacting with RNA. Costales MG, Suresh B, Vishnu K, Disney MD Cell chemical biology 31130520 Cell Chem Biol 2019 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/31130520
The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology. Chen JL, Moss WN, Spencer A, Zhang P, Childs-Disney JL, Disney MD PloS one 31291322 PLoS One 2019 https://www.ncbi.nlm.nih.gov/pubmed/31291322
Identifying and validating small molecules interacting with RNA (SMIRNAs). Disney MD, Velagapudi SP, Li Y, Costales MG, Childs-Disney JL Methods in enzymology 31239057 Methods Enzymol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31239057
Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA. Zhang P, Park HJ, Zhang J, Junn E, Andrews RJ, Velagapudi SP, Abegg D, Vishnu K, Costales MG, Childs-Disney JL, Adibekian A, Moss WN, Mouradian MM, Disney MD Proceedings of the National Academy of Sciences of the United States of America 31900363 Proc Natl Acad Sci U S A 2020 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/31900363
A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome Complex. Angelbello AJ, Benhamou RI, Rzuczek SG, Choudhary S, Tang Z, Chen JL, Roy M, Wang KW, Yildirim I, Jun AS, Thornton CA, Disney MD Cell chemical biology 33157036 Cell Chem Biol 2021 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/33157036
Macrocyclization of a Ligand Targeting a Toxic RNA Dramatically Improves Potency. Benhamou RI, Vezina-Dawod S, Choudhary S, Won Wang K, Meyer SM, Yildirim I, Disney MD Chembiochem : a European journal of chemical biology 32649032 Chembiochem 2020 Nov 16 https://www.ncbi.nlm.nih.gov/pubmed/32649032
Small molecule recognition of disease-relevant RNA structures. Meyer SM, Williams CC, Akahori Y, Tanaka T, Aikawa H, Tong Y, Childs-Disney JL, Disney MD Chemical Society reviews 32975549 Chem Soc Rev 2020 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/32975549
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G(4)C(2)) repeat expansion in vitro and in vivo ALS models. Bush JA, Aikawa H, Fuerst R, Li Y, Ursu A, Meyer SM, Benhamou RI, Chen JL, Khan T, Wagner-Griffin S, Van Meter MJ, Tong Y, Olafson H, McKee KK, Childs-Disney JL, Gendron TF, Zhang Y, Coyne AN, Wang ET, Yildirim I, Wang KW, Petrucelli L, Rothstein JD, Disney MD Science translational medicine 34705518 Sci Transl Med 2021 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/34705518
CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca(2+) Signals during LTP Induction, but Not Maintenance. Chang JY, Parra-Bueno P, Laviv T, Szatmari EM, Lee SR, Yasuda R Neuron 28521133 Neuron 2017 May 17 https://www.ncbi.nlm.nih.gov/pubmed/28521133
Autocrine BDNF-TrkB signalling within a single dendritic spine. Harward SC, Hedrick NG, Hall CE, Parra-Bueno P, Milner TA, Pan E, Laviv T, Hempstead BL, Yasuda R, McNamara JO Nature 27680698 Nature 2016 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/27680698
High-Throughput, High-Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing. Mikuni T, Nishiyama J, Sun Y, Kamasawa N, Yasuda R Cell 27180908 Cell 2016 Jun 16 https://www.ncbi.nlm.nih.gov/pubmed/27180908
Simultaneous dual-color fluorescence lifetime imaging with novel red-shifted fluorescent proteins. Laviv T, Kim BB, Chu J, Lam AJ, Lin MZ, Yasuda R Nature methods 27798609 Nat Methods 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27798609
Plasticity of Spine Structure: Local Signaling, Translation and Cytoskeletal Reorganization. Nakahata Y, Yasuda R Frontiers in synaptic neuroscience 30210329 Front Synaptic Neurosci 2018 https://www.ncbi.nlm.nih.gov/pubmed/30210329
Rapid Ultrastructural Changes in the PSD and Surrounding Membrane after Induction of Structural LTP in Single Dendritic Spines. Sun Y, Smirnov M, Kamasawa N, Yasuda R The Journal of neuroscience : the official journal of the Society for Neuroscience 34266899 J Neurosci 2021 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/34266899
In Vivo Imaging of the Coupling between Neuronal and CREB Activity in the Mouse Brain. Laviv T, Scholl B, Parra-Bueno P, Foote B, Zhang C, Yan L, Hayano Y, Chu J, Yasuda R Neuron 31883788 Neuron 2020 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/31883788
PKCα integrates spatiotemporally distinct Ca(2+) and autocrine BDNF signaling to facilitate synaptic plasticity. Colgan LA, Hu M, Misler JA, Parra-Bueno P, Moran CM, Leitges M, Yasuda R Nature neuroscience 30013171 Nat Neurosci 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/30013171
Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation. Wang J, Nishiyama J, Parra-Bueno P, Okaz E, Oz G, Liu X, Watabe T, Suponitsky-Kroyter I, McGraw TE, Szatmari EM, Yasuda R bioRxiv : the preprint server for biology 40501544 bioRxiv 2025 Aug 27 https://www.ncbi.nlm.nih.gov/pubmed/40501544
Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity. Hedrick NG, Harward SC, Hall CE, Murakoshi H, McNamara JO, Yasuda R Nature 27680697 Nature 2016 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/27680697
Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor. Murakoshi H, Shin ME, Parra-Bueno P, Szatmari EM, Shibata ACE, Yasuda R Neuron 28318784 Neuron 2017 Apr 5 https://www.ncbi.nlm.nih.gov/pubmed/28318784
Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain. Nishiyama J, Mikuni T, Yasuda R Neuron 29056297 Neuron 2017 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/29056297
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Feasibility of 3D Reconstruction of Neural Morphology Using Expansion Microscopy and Barcode-Guided Agglomeration. Yoon YG, Dai P, Wohlwend J, Chang JB, Marblestone AH, Boyden ES Frontiers in computational neuroscience 29114215 Front Comput Neurosci 2017 https://www.ncbi.nlm.nih.gov/pubmed/29114215
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Precision Calcium Imaging of Dense Neural Populations via a Cell-Body-Targeted Calcium Indicator. Shemesh OA, Linghu C, Piatkevich KD, Goodwin D, Celiker OT, Gritton HJ, Romano MF, Gao R, Yu CJ, Tseng HA, Bensussen S, Narayan S, Yang CT, Freifeld L, Siciliano CA, Gupta I, Wang J, Pak N, Yoon YG, Ullmann JFP, Guner-Ataman B, Noamany H, Sheinkopf ZR, Park WM, Asano S, Keating AE, Trimmer JS, Reimer J, Tolias AS, Bear MF, Tye KM, Han X, Ahrens MB, Boyden ES Neuron 32592656 Neuron 2020 Aug 5 https://www.ncbi.nlm.nih.gov/pubmed/32592656
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Assembly and operation of the autopatcher for automated intracellular neural recording in vivo. Kodandaramaiah SB, Holst GL, Wickersham IR, Singer AC, Franzesi GT, McKinnon ML, Forest CR, Boyden ES Nature protocols 26938115 Nat Protoc 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26938115
Close-Packed Silicon Microelectrodes for Scalable Spatially Oversampled Neural Recording. Scholvin J, Kinney JP, Bernstein JG, Moore-Kochlacs C, Kopell N, Fonstad CG, Boyden ES IEEE transactions on bio-medical engineering 26699649 IEEE Trans Biomed Eng 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/26699649
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A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve. Caravaca AS, Tsaava T, Goldman L, Silverman H, Riggott G, Chavan SS, Bouton C, Tracey KJ, Desimone R, Boyden ES, Sohal HS, Olofsson PS Journal of neural engineering 28628030 J Neural Eng 2017 Dec https://www.ncbi.nlm.nih.gov/pubmed/28628030
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Engineering genetic circuit interactions within and between synthetic minimal cells. Adamala KP, Martin-Alarcon DA, Guthrie-Honea KR, Boyden ES Nature chemistry 28430194 Nat Chem 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28430194
Sonofragmentation of Ultrathin 1D Nanomaterials. Gao R, Gupta I, Boyden ES Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems 28804214 Part Part Syst Charact 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/28804214
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Revealing nanostructures in brain tissue via protein decrowding by iterative expansion microscopy. Sarkar D, Kang J, Wassie AT, Schroeder ME, Peng Z, Tarr TB, Tang AH, Niederst ED, Young JZ, Su H, Park D, Yin P, Tsai LH, Blanpied TA, Boyden ES Nature biomedical engineering 36038771 Nat Biomed Eng 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/36038771
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Scalable, Modular Three-Dimensional Silicon Microelectrode Assembly via Electroless Plating. Scholvin J, Zorzos A, Kinney J, Bernstein J, Moore-Kochlacs C, Kopell N, Fonstad C, Boyden ES Micromachines 30424369 Micromachines (Basel) 2018 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/30424369
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CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Joung J, Kirchgatterer PC, Singh A, Cho JH, Nety SP, Larson RC, Macrae RK, Deasy R, Tseng YY, Maus MV, Zhang F Nature communications 35338135 Nat Commun 2022 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/35338135
The evolution of red color vision is linked to coordinated rhodopsin tuning in lycaenid butterflies. Liénard MA, Bernard GD, Allen A, Lassance JM, Song S, Childers RR, Yu N, Ye D, Stephenson A, Valencia-Montoya WA, Salzman S, Whitaker MRL, Calonje M, Zhang F, Pierce NE Proceedings of the National Academy of Sciences of the United States of America 33547236 Proc Natl Acad Sci U S A 2021 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/33547236
LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding. Ludwig KU, Schmithausen RM, Li D, Jacobs ML, Hollstein R, Blumenstock K, Liebing J, Słabicki M, Ben-Shmuel A, Israeli O, Weiss S, Ebert TS, Paran N, Rüdiger W, Wilbring G, Feldman D, Lippke B, Ishorst N, Hochfeld LM, Beins EC, Kaltheuner IH, Schmitz M, Wöhler A, Döhla M, Sib E, Jentzsch M, Moench EC, Borrajo JD, Strecker J, Reinhardt J, Cleary B, Geyer M, Hölzel M, Macrae R, Nöthen MM, Hoffmann P, Exner M, Regev A, Zhang F, Schmid-Burgk JL Nature biotechnology 34188222 Nat Biotechnol 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/34188222
Sodium current reduction unmasks a structure-dependent substrate for arrhythmogenesis in the normal ventricles. Boyle PM, Park CJ, Arevalo HJ, Vigmond EJ, Trayanova NA PloS one 24489810 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/24489810
Image-based left ventricular shape analysis for sudden cardiac death risk stratification. Vadakkumpadan F, Trayanova N, Wu KC Heart rhythm 24854217 Heart Rhythm 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/24854217
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling. Wright PT, Nikolaev VO, O'Hara T, Diakonov I, Bhargava A, Tokar S, Schobesberger S, Shevchuk AI, Sikkel MB, Wilkinson R, Trayanova NA, Lyon AR, Harding SE, Gorelik J Journal of molecular and cellular cardiology 24345421 J Mol Cell Cardiol 2014 Feb https://www.ncbi.nlm.nih.gov/pubmed/24345421
Exploring susceptibility to atrial and ventricular arrhythmias resulting from remodeling of the passive electrical properties in the heart: a simulation approach. Trayanova NA, Boyle PM, Arevalo HJ, Zahid S Frontiers in physiology 25429272 Front Physiol 2014 https://www.ncbi.nlm.nih.gov/pubmed/25429272
"Beauty is a light in the heart": the transformative potential of optogenetics for clinical applications in cardiovascular medicine. Boyle PM, Karathanos TV, Trayanova NA Trends in cardiovascular medicine 25453984 Trends Cardiovasc Med 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25453984
Myocardial infarct segmentation and reconstruction from 2D late-gadolinium enhanced magnetic resonance images. Ukwatta E, Yuan J, Qiu W, Wu KC, Trayanova N, Vadakkumpadan F Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 25485423 Med Image Comput Comput Assist Interv 2014 https://www.ncbi.nlm.nih.gov/pubmed/25485423
Sensitivity of Ablation Targets Prediction to Electrophysiological Parameter Variability in Image-Based Computational Models of Ventricular Tachycardia in Post-infarction Patients. Deng D, Prakosa A, Shade J, Nikolov P, Trayanova NA Frontiers in physiology 31178758 Front Physiol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31178758
Computationally guided personalized targeted ablation of persistent atrial fibrillation. Boyle PM, Zghaib T, Zahid S, Ali RL, Deng D, Franceschi WH, Hakim JB, Murphy MJ, Prakosa A, Zimmerman SL, Ashikaga H, Marine JE, Kolandaivelu A, Nazarian S, Spragg DD, Calkins H, Trayanova NA Nature biomedical engineering 31427780 Nat Biomed Eng 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31427780
Increased thin filament activation enhances alternans in human chronic atrial fibrillation. Zile MA, Trayanova NA American journal of physiology. Heart and circulatory physiology 30141984 Am J Physiol Heart Circ Physiol 2018 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/30141984
Cardiac Optogenetics: 2018. Boyle PM, Karathanos TV, Trayanova NA JACC. Clinical electrophysiology 29749932 JACC Clin Electrophysiol 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29749932
Virtual electrophysiological study as a tool for evaluating efficacy of MRI techniques in predicting adverse arrhythmic events in ischemic patients. Ukwatta E, Nikolov P, Zabihollahy F, Trayanova NA, Wright GA Physics in medicine and biology 30412472 Phys Med Biol 2018 Nov 9 https://www.ncbi.nlm.nih.gov/pubmed/30412472
Substrate Spatial Complexity Analysis for the Prediction of Ventricular Arrhythmias in Patients With Ischemic Cardiomyopathy. Okada DR, Miller J, Chrispin J, Prakosa A, Trayanova N, Jones S, Maggioni M, Wu KC Circulation. Arrhythmia and electrophysiology 32188287 Circ Arrhythm Electrophysiol 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32188287
Accurate Conduction Velocity Maps and Their Association With Scar Distribution on Magnetic Resonance Imaging in Patients With Postinfarction Ventricular Tachycardias. Aronis KN, Ali RL, Prakosa A, Ashikaga H, Berger RD, Hakim JB, Liang J, Tandri H, Teng F, Chrispin J, Trayanova NA Circulation. Arrhythmia and electrophysiology 32191131 Circ Arrhythm Electrophysiol 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32191131
How computer simulations of the human heart can improve anti-arrhythmia therapy. Trayanova NA, Chang KC The Journal of physiology 26621489 J Physiol 2016 May 1 https://www.ncbi.nlm.nih.gov/pubmed/26621489
Image-based Reconstruction of 3D Myocardial Infarct Geometry for Patient Specific Applications. Ukwatta E, Rajchl M, White J, Pashakhanloo F, Herzka DA, McVeigh E, Lardo AC, Trayanova N, Vadakkumpadan F Proceedings of SPIE--the International Society for Optical Engineering 26633913 Proc SPIE Int Soc Opt Eng 2015 Feb 21 https://www.ncbi.nlm.nih.gov/pubmed/26633913
Corrigendum to "effects of fibrosis morphology on reentrant ventricular tachycardia inducibility and simulation fidelity in patient-derived models". Ringenberg J, Deo M, Filgueiras-Rama D, Pizarro G, Ibañez B, Peinado R, Trayanova N, Miller M, Merino JL, Berenfeld O, Devabhaktuni V Clinical Medicine Insights. Cardiology 25698881 Clin Med Insights Cardiol 2014 https://www.ncbi.nlm.nih.gov/pubmed/25698881
Computational modeling of aberrant electrical activity following remuscularization with intramyocardially injected pluripotent stem cell-derived cardiomyocytes. Yu JK, Liang JA, Weinberg SH, Trayanova NA Journal of molecular and cellular cardiology 34487753 J Mol Cell Cardiol 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34487753
Disrupted calcium release as a mechanism for atrial alternans associated with human atrial fibrillation. Chang KC, Bayer JD, Trayanova NA PLoS computational biology 25501557 PLoS Comput Biol 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25501557
Computational models of heart disease. Smith N, Trayanova N Drug discovery today. Disease models 26843884 Drug Discov Today Dis Models 2014 Winter https://www.ncbi.nlm.nih.gov/pubmed/26843884
Myocardial Infarct Segmentation From Magnetic Resonance Images for Personalized Modeling of Cardiac Electrophysiology. Ukwatta E, Arevalo H, Li K, Yuan J, Qiu W, Malamas P, Wu KC, Trayanova NA, Vadakkumpadan F IEEE transactions on medical imaging 26731693 IEEE Trans Med Imaging 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/26731693
Spatially Adaptive Multi-Scale Optimization for Local Parameter Estimation in Cardiac Electrophysiology. Dhamala J, Arevalo HJ, Sapp J, Horacek M, Wu KC, Trayanova NA, Wang L IEEE transactions on medical imaging 28459685 IEEE Trans Med Imaging 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/28459685
Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm. Cerrone M, Montnach J, Lin X, Zhao YT, Zhang M, Agullo-Pascual E, Leo-Macias A, Alvarado FJ, Dolgalev I, Karathanos TV, Malkani K, Van Opbergen CJM, van Bavel JJA, Yang HQ, Vasquez C, Tester D, Fowler S, Liang F, Rothenberg E, Heguy A, Morley GE, Coetzee WA, Trayanova NA, Ackerman MJ, van Veen TAB, Valdivia HH, Delmar M Nature communications 28740174 Nat Commun 2017 Jul 24 https://www.ncbi.nlm.nih.gov/pubmed/28740174
Opsin spectral sensitivity determines the effectiveness of optogenetic termination of ventricular fibrillation in the human heart: a simulation study. Karathanos TV, Bayer JD, Wang D, Boyle PM, Trayanova NA The Journal of physiology 26941055 J Physiol 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/26941055
Towards personalized computational modelling of the fibrotic substrate for atrial arrhythmia. Boyle PM, Zahid S, Trayanova NA Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 28011841 Europace 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/28011841
Modelling methodology of atrial fibrosis affects rotor dynamics and electrograms. Roney CH, Bayer JD, Zahid S, Meo M, Boyle PM, Trayanova NA, Haïssaguerre M, Dubois R, Cochet H, Vigmond EJ Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 28011842 Europace 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/28011842
A New MRI-Based Model of Heart Function with Coupled Hemodynamics and Application to Normal and Diseased Canine Left Ventricles. Choi YJ, Constantino J, Vedula V, Trayanova N, Mittal R Frontiers in bioengineering and biotechnology 26442254 Front Bioeng Biotechnol 2015 https://www.ncbi.nlm.nih.gov/pubmed/26442254
Quantifying the uncertainty in model parameters using Gaussian process-based Markov chain Monte Carlo in cardiac electrophysiology. Dhamala J, Arevalo HJ, Sapp J, Horácek BM, Wu KC, Trayanova NA, Wang L Medical image analysis 29843078 Med Image Anal 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29843078
Efficient preloading of the ventricles by a properly timed atrial contraction underlies stroke work improvement in the acute response to cardiac resynchronization therapy. Hu Y, Gurev V, Constantino J, Trayanova N Heart rhythm 23928177 Heart Rhythm 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/23928177
Mathematical approaches to understanding and imaging atrial fibrillation: significance for mechanisms and management. Trayanova NA Circulation research 24763468 Circ Res 2014 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/24763468
Epicardial Conduction Speed, Electrogram Abnormality, and Computed Tomography Attenuation Associations in Arrhythmogenic Right Ventricular Cardiomyopathy. Ustunkaya T, Desjardins B, Wedan R, Chahal CAA, Zimmerman SL, Saju N, Zahid S, Sharma A, Han Y, Trayanova N, Marchlinski FE, Calkins H, Tandri H, Nazarian S JACC. Clinical electrophysiology 31648740 JACC Clin Electrophysiol 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31648740
Optimal contrast-enhanced MRI image thresholding for accurate prediction of ventricular tachycardia using ex-vivo high resolution models. Deng D, Nikolov P, Arevalo HJ, Trayanova NA Computers in biology and medicine 30301573 Comput Biol Med 2018 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/30301573
From genetics to smart watches: developments in precision cardiology. Trayanova N Nature reviews. Cardiology 30568275 Nat Rev Cardiol 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30568275
Initiation of a High-Frequency Jet Ventilation Strategy for Catheter Ablation for Atrial Fibrillation: Safety and Outcomes Data. Sivasambu B, Hakim JB, Barodka V, Chrispin J, Berger RD, Ashikaga H, Ciuffo L, Tao S, Calkins H, Marine JE, Trayanova N, Spragg DD JACC. Clinical electrophysiology 30573114 JACC Clin Electrophysiol 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30573114
Degradation of T-Tubular Microdomains and Altered cAMP Compartmentation Lead to Emergence of Arrhythmogenic Triggers in Heart Failure Myocytes: An in silico Study. Loucks AD, O'Hara T, Trayanova NA Frontiers in physiology 30564142 Front Physiol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30564142
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Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria. Mor DE, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, Miller GW, Murphy CT Proceedings of the National Academy of Sciences of the United States of America 33024014 Proc Natl Acad Sci U S A 2020 Oct 20 https://www.ncbi.nlm.nih.gov/pubmed/33024014
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Caenorhabditis elegans sperm carry a histone-based epigenetic memory of both spermatogenesis and oogenesis. Tabuchi TM, Rechtsteiner A, Jeffers TE, Egelhofer TA, Murphy CT, Strome S Nature communications 30333496 Nat Commun 2018 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/30333496
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The usual suspects, dopamine and alpha-synuclein, conspire to cause neurodegeneration. Mor DE, Daniels MJ, Ischiropoulos H Movement disorders : official journal of the Movement Disorder Society 30633814 Mov Disord 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30633814
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Regulation of reproduction and longevity by nutrient-sensing pathways. Templeman NM, Murphy CT The Journal of cell biology 29074705 J Cell Biol 2018 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/29074705
Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis. Wang J, Kaletsky R, Silva M, Williams A, Haas LA, Androwski RJ, Landis JN, Patrick C, Rashid A, Santiago-Martinez D, Gravato-Nobre M, Hodgkin J, Hall DH, Murphy CT, Barr MM Current biology : CB 26687621 Curr Biol 2015 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/26687621
Novel elasticity measurements reveal C. elegans cuticle stiffens with age and in a long-lived mutant. Rahimi M, Sohrabi S, Murphy CT Biophysical journal 35065051 Biophys J 2022 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/35065051
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A natural bacterial pathogen of C. elegans uses a small RNA to induce transgenerational inheritance of learned avoidance. Sengupta T, St Ange J, Moore R, Kaletsky R, Marogi J, Myhrvold C, Gitai Z, Murphy CT bioRxiv : the preprint server for biology 37503135 bioRxiv 2023 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/37503135
Pseudomonas fluorescens 15 small RNA Pfs1 mediates transgenerational epigenetic inheritance of pathogen avoidance in C. elegans through the Ephrin receptor VAB-1. Seto R, Brown R, Kaletsky R, Parsons LR, Moore RS, Murphy CT bioRxiv : the preprint server for biology 38826453 bioRxiv 2024 May 23 https://www.ncbi.nlm.nih.gov/pubmed/38826453
Single cell analysis reveals multiple requirements for zinc in the mammalian cell cycle. Lo MN, Damon LJ, Wei Tay J, Jia S, Palmer AE eLife 32014109 Elife 2020 Feb 4 https://www.ncbi.nlm.nih.gov/pubmed/32014109
Remodeling of Zn(2+) homeostasis upon differentiation of mammary epithelial cells. Han Y, Sanford L, Simpson DM, Dowell RD, Palmer AE Metallomics : integrated biometal science 31950952 Metallomics 2020 Mar 25 https://www.ncbi.nlm.nih.gov/pubmed/31950952
Directed Evolution of a Bright Variant of mCherry: Suppression of Nonradiative Decay by Fluorescence Lifetime Selections. Mukherjee S, Manna P, Hung ST, Vietmeyer F, Friis P, Palmer AE, Jimenez R The journal of physical chemistry. B 35709514 J Phys Chem B 2022 Jun 30 https://www.ncbi.nlm.nih.gov/pubmed/35709514
Zn(2+) influx activates ERK and Akt signaling pathways. Anson KJ, Corbet GA, Palmer AE Proceedings of the National Academy of Sciences of the United States of America 33712543 Proc Natl Acad Sci U S A 2021 Mar 16 https://www.ncbi.nlm.nih.gov/pubmed/33712543
Intracellular Zn(2+) transients modulate global gene expression in dissociated rat hippocampal neurons. Sanford L, Carpenter MC, Palmer AE Scientific reports 31253848 Sci Rep 2019 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/31253848
Intramolecular Fluorescent Protein Association in a Class of Zinc FRET Sensors Leads to Increased Dynamic Range. Slocum JD, Palmer AE, Jimenez R The journal of physical chemistry. B 30942588 J Phys Chem B 2019 Apr 11 https://www.ncbi.nlm.nih.gov/pubmed/30942588
Human cells experience a Zn(2+) pulse in early G1. Rakshit A, Holtzen SE, Lo MN, Conway KA, Palmer AE Cell reports 37330912 Cell Rep 2023 Jun 27 https://www.ncbi.nlm.nih.gov/pubmed/37330912
Droplet Microfluidic Flow Cytometer For Sorting On Transient Cellular Responses Of Genetically-Encoded Sensors. Fiedler BL, Van Buskirk S, Carter KP, Qin Y, Carpenter MC, Palmer AE, Jimenez R Analytical chemistry 27959493 Anal Chem 2017 Jan 3 https://www.ncbi.nlm.nih.gov/pubmed/27959493
Systematic Comparison of Vesicular Targeting Signals Leads to the Development of Genetically Encoded Vesicular Fluorescent Zn(2+) and pH Sensors. Pratt EPS, Anson KJ, Tapper JK, Simpson DM, Palmer AE ACS sensors 33305939 ACS Sens 2020 Dec 24 https://www.ncbi.nlm.nih.gov/pubmed/33305939
Illuminating RNA Biology: Tools for Imaging RNA in Live Mammalian Cells. Braselmann E, Rathbun C, Richards EM, Palmer AE Cell chemical biology 32640188 Cell Chem Biol 2020 Aug 20 https://www.ncbi.nlm.nih.gov/pubmed/32640188
Discovery of a ZIP7 inhibitor from a Notch pathway screen. Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ Nature chemical biology 30643281 Nat Chem Biol 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30643281
Erratum: Directed evolution of excited state lifetime and brightness in FusionRed using a microfluidic sorter. Manna P, Hung ST, Mukherjee S, Friis P, Simpson DM, Lo M, Palmer AE, Jimenez R Integrative biology : quantitative biosciences from nano to macro 31788687 Integr Biol (Camb) 2019 Dec 31 https://www.ncbi.nlm.nih.gov/pubmed/31788687
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. Braselmann E, Wierzba AJ, Polaski JT, Chromiński M, Holmes ZE, Hung ST, Batan D, Wheeler JR, Parker R, Jimenez R, Gryko D, Batey RT, Palmer AE Nature chemical biology 30061719 Nat Chem Biol 2018 Oct https://www.ncbi.nlm.nih.gov/pubmed/30061719
Protocol for measuring cell cycle Zn(2+) dynamics using a FRET-based biosensor. Holtzen SE, Rakshit A, Palmer AE STAR protocols 38861382 STAR Protoc 2024 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/38861382
The Growing and Glowing Toolbox of Fluorescent and Photoactive Proteins. Rodriguez EA, Campbell RE, Lin JY, Lin MZ, Miyawaki A, Palmer AE, Shu X, Zhang J, Tsien RY Trends in biochemical sciences 27814948 Trends Biochem Sci 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/27814948
Critical Comparison of FRET-Sensor Functionality in the Cytosol and Endoplasmic Reticulum and Implications for Quantification of Ions. Carter KP, Carpenter MC, Fiedler B, Jimenez R, Palmer AE Analytical chemistry 28758723 Anal Chem 2017 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/28758723
Single molecule microscopy to profile the effect of zinc status on transcription factor dynamics. Damon LJ, Aaron J, Palmer AE Scientific reports 36273101 Sci Rep 2022 Oct 22 https://www.ncbi.nlm.nih.gov/pubmed/36273101
Native and engineered sensors for Ca(2+) and Zn(2+): lessons from calmodulin and MTF1. Carpenter MC, Palmer AE Essays in biochemistry 28487400 Essays Biochem 2017 May 9 https://www.ncbi.nlm.nih.gov/pubmed/28487400
Techniques for measuring cellular zinc. Carpenter MC, Lo MN, Palmer AE Archives of biochemistry and biophysics 27580940 Arch Biochem Biophys 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27580940
A Critical and Comparative Review of Fluorescent Tools for Live-Cell Imaging. Specht EA, Braselmann E, Palmer AE Annual review of physiology 27860833 Annu Rev Physiol 2017 Feb 10 https://www.ncbi.nlm.nih.gov/pubmed/27860833
Directed evolution of excited state lifetime and brightness in FusionRed using a microfluidic sorter. Manna P, Hung ST, Mukherjee S, Friis P, Simpson DM, Lo MN, Palmer AE, Jimenez R Integrative biology : quantitative biosciences from nano to macro 30094420 Integr Biol (Camb) 2018 Sep 17 https://www.ncbi.nlm.nih.gov/pubmed/30094420
Zinc transporters belonging to the Cation Diffusion Facilitator (CDF) family have complementary roles in transporting zinc out of the cytosol. Choi S, Hu YM, Corkins ME, Palmer AE, Bird AJ PLoS genetics 29529046 PLoS Genet 2018 Mar https://www.ncbi.nlm.nih.gov/pubmed/29529046
Superiority of SpiroZin2 Versus FluoZin-3 for monitoring vesicular Zn(2+) allows tracking of lysosomal Zn(2+) pools. Han Y, Goldberg JM, Lippard SJ, Palmer AE Scientific reports 30302024 Sci Rep 2018 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/30302024
Dissociated Hippocampal Neurons Exhibit Distinct Zn(2+) Dynamics in a Stimulation-Method-Dependent Manner. Sanford L, Palmer AE ACS chemical neuroscience 32013397 ACS Chem Neurosci 2020 Feb 19 https://www.ncbi.nlm.nih.gov/pubmed/32013397
A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. Braselmann E, Palmer AE Methods in enzymology 32713529 Methods Enzymol 2020 https://www.ncbi.nlm.nih.gov/pubmed/32713529
Tools and techniques for illuminating the cell biology of zinc. Pratt EPS, Damon LJ, Anson KJ, Palmer AE Biochimica et biophysica acta. Molecular cell research 32980354 Biochim Biophys Acta Mol Cell Res 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/32980354
Engineering of a Brighter Variant of the FusionRed Fluorescent Protein Using Lifetime Flow Cytometry and Structure-Guided Mutations. Mukherjee S, Hung ST, Douglas N, Manna P, Thomas C, Ekrem A, Palmer AE, Jimenez R Biochemistry 32914619 Biochemistry 2020 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/32914619
Characterization of Global Gene Expression, Regulation of Metal Ions, and Infection Outcomes in Immune-Competent 129S6 Mouse Macrophages. Janiszewski LN, Minson M, Allen MA, Dowell RD, Palmer AE Infection and immunity 34370511 Infect Immun 2021 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/34370511
Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. Fowler BJ, Gelfand BD, Kim Y, Kerur N, Tarallo V, Hirano Y, Amarnath S, Fowler DH, Radwan M, Young MT, Pittman K, Kubes P, Agarwal HK, Parang K, Hinton DR, Bastos-Carvalho A, Li S, Yasuma T, Mizutani T, Yasuma R, Wright C, Ambati J Science (New York, N.Y.) 25414314 Science 2014 Nov 21 https://www.ncbi.nlm.nih.gov/pubmed/25414314
Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models. Cicatiello V, Apicella I, Tudisco L, Tarallo V, Formisano L, Sandomenico A, Kim Y, Bastos-Carvalho A, Orlandi A, Ambati J, Ruvo M, Bianco R, De Falco S Oncotarget 25868854 Oncotarget 2015 Apr 30 https://www.ncbi.nlm.nih.gov/pubmed/25868854
Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J Signal transduction and targeted therapy 26918197 Signal Transduct Target Ther 2016 https://www.ncbi.nlm.nih.gov/pubmed/26918197
A Revised Hemodynamic Theory of Age-Related Macular Degeneration. Gelfand BD, Ambati J Trends in molecular medicine 27423265 Trends Mol Med 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27423265
L1 drives IFN in senescent cells and promotes age-associated inflammation. De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM Nature 30728521 Nature 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30728521
IL-18 is not therapeutic for neovascular age-related macular degeneration. Hirano Y, Yasuma T, Mizutani T, Fowler BJ, Tarallo V, Yasuma R, Kim Y, Bastos-Carvalho A, Kerur N, Gelfand BD, Bogdanovich S, He S, Zhang X, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Nagai H, Haro I, Núñez G, Ambati BK, Hinton DR, Ambati J Nature medicine 25473914 Nat Med 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25473914
Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice. Mizutani T, Fowler BJ, Kim Y, Yasuma R, Krueger LA, Gelfand BD, Ambati J Investigative ophthalmology & visual science 26529046 Invest Ophthalmol Vis Sci 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26529046
Voluntary Exercise Suppresses Choroidal Neovascularization in Mice. Makin RD, Argyle D, Hirahara S, Nagasaka Y, Zhang M, Yan Z, Kerur N, Ambati J, Gelfand BD Investigative ophthalmology & visual science 32460310 Invest Ophthalmol Vis Sci 2020 May 11 https://www.ncbi.nlm.nih.gov/pubmed/32460310
RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes. Makin RD, Apicella I, Nagasaka Y, Kaneko H, Turner SD, Kerur N, Ambati J, Gelfand BD Investigative ophthalmology & visual science 30508043 Invest Ophthalmol Vis Sci 2018 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/30508043
Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism. Al-Khalidi R, Panicucci C, Cox P, Chira N, Róg J, Young CNJ, McGeehan RE, Ambati K, Ambati J, Zabłocki K, Gazzerro E, Arkle S, Bruno C, Górecki DC Acta neuropathologica communications 29642926 Acta Neuropathol Commun 2018 Apr 11 https://www.ncbi.nlm.nih.gov/pubmed/29642926
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Kerur N, Fukuda S, Banerjee D, Kim Y, Fu D, Apicella I, Varshney A, Yasuma R, Fowler BJ, Baghdasaryan E, Marion KM, Huang X, Yasuma T, Hirano Y, Serbulea V, Ambati M, Ambati VL, Kajiwara Y, Ambati K, Hirahara S, Bastos-Carvalho A, Ogura Y, Terasaki H, Oshika T, Kim KB, Hinton DR, Leitinger N, Cambier JC, Buxbaum JD, Kenney MC, Jazwinski SM, Nagai H, Hara I, West AP, Fitzgerald KA, Sadda SR, Gelfand BD, Ambati J Nature medicine 29176737 Nat Med 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29176737
Dry Age-Related Macular Degeneration Pharmacology. Wright CB, Ambati J Handbook of experimental pharmacology 27900609 Handb Exp Pharmacol 2017 https://www.ncbi.nlm.nih.gov/pubmed/27900609
A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling. Banerjee D, Langberg K, Abbas S, Odermatt E, Yerramothu P, Volaric M, Reidenbach MA, Krentz KJ, Rubinstein CD, Brautigan DL, Abbas T, Gelfand BD, Ambati J, Kerur N Nature communications 34707113 Nat Commun 2021 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/34707113
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J Science immunology 34860583 Sci Immunol 2021 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/34860583
Intravenous immune globulin suppresses angiogenesis in mice and humans. Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J Signal transduction and targeted therapy 26925256 Signal Transduct Target Ther 2016 https://www.ncbi.nlm.nih.gov/pubmed/26925256
Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome. Gelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Núñez G, Georgel P, Dunaief JL, Ambati J Cell reports 26074074 Cell Rep 2015 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/26074074
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration. Fukuda S, Varshney A, Fowler BJ, Wang SB, Narendran S, Ambati K, Yasuma T, Magagnoli J, Leung H, Hirahara S, Nagasaka Y, Yasuma R, Apicella I, Pereira F, Makin RD, Magner E, Liu X, Sun J, Wang M, Baker K, Marion KM, Huang X, Baghdasaryan E, Ambati M, Ambati VL, Pandey A, Pandya L, Cummings T, Banerjee D, Huang P, Yerramothu P, Tolstonog GV, Held U, Erwin JA, Paquola ACM, Herdy JR, Ogura Y, Terasaki H, Oshika T, Darwish S, Singh RK, Mozaffari S, Bhattarai D, Kim KB, Hardin JW, Bennett CL, Hinton DR, Hanson TE, Röver C, Parang K, Kerur N, Liu J, Werner BC, Sutton SS, Sadda SR, Schumann GG, Gelfand BD, Gage FH, Ambati J Proceedings of the National Academy of Sciences of the United States of America 33526699 Proc Natl Acad Sci U S A 2021 Feb 9 https://www.ncbi.nlm.nih.gov/pubmed/33526699
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice. Wright CB, Uehara H, Kim Y, Yasuma T, Yasuma R, Hirahara S, Makin RD, Apicella I, Pereira F, Nagasaka Y, Narendran S, Fukuda S, Albuquerque R, Fowler BJ, Bastos-Carvalho A, Georgel P, Hatada I, Chang B, Kerur N, Ambati BK, Ambati J, Gelfand BD Proceedings of the National Academy of Sciences of the United States of America 31964819 Proc Natl Acad Sci U S A 2020 Feb 4 https://www.ncbi.nlm.nih.gov/pubmed/31964819
DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration. Kim Y, Tarallo V, Kerur N, Yasuma T, Gelfand BD, Bastos-Carvalho A, Hirano Y, Yasuma R, Mizutani T, Fowler BJ, Li S, Kaneko H, Bogdanovich S, Ambati BK, Hinton DR, Hauswirth WW, Hakem R, Wright C, Ambati J Proceedings of the National Academy of Sciences of the United States of America 25349431 Proc Natl Acad Sci U S A 2014 Nov 11 https://www.ncbi.nlm.nih.gov/pubmed/25349431
Photoswitchable fluorescent proteins: ten years of colorful chemistry and exciting applications. Zhou XX, Lin MZ Current opinion in chemical biology 23876529 Curr Opin Chem Biol 2013 Aug https://www.ncbi.nlm.nih.gov/pubmed/23876529
Optical control of biological processes by light-switchable proteins. Fan LZ, Lin MZ Wiley interdisciplinary reviews. Developmental biology 25858669 Wiley Interdiscip Rev Dev Biol 2015 Sep-Oct https://www.ncbi.nlm.nih.gov/pubmed/25858669
Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments. Welf ES, Driscoll MK, Dean KM, Schäfer C, Chu J, Davidson MW, Lin MZ, Danuser G, Fiolka R Developmental cell 26906741 Dev Cell 2016 Feb 22 https://www.ncbi.nlm.nih.gov/pubmed/26906741
Genetically encoded indicators of neuronal activity. Lin MZ, Schnitzer MJ Nature neuroscience 27571193 Nat Neurosci 2016 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/27571193
Fluorescent indicators for simultaneous reporting of all four cell cycle phases. Bajar BT, Lam AJ, Badiee RK, Oh YH, Chu J, Zhou XX, Kim N, Kim BB, Chung M, Yablonovitch AL, Cruz BF, Kulalert K, Tao JJ, Meyer T, Su XD, Lin MZ Nature methods 27798610 Nat Methods 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27798610
Structure-guided wavelength tuning in far-red fluorescent proteins. Ng HL, Lin MZ Current opinion in structural biology 27468111 Curr Opin Struct Biol 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27468111
An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging. Oh Y, Park Y, Cho JH, Wu H, Paulk NK, Liu LX, Kim N, Kay MA, Wu JC, Lin MZ Nature chemical biology 30936501 Nat Chem Biol 2019 May https://www.ncbi.nlm.nih.gov/pubmed/30936501
A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription. Zhou XX, Zou X, Chung HK, Gao Y, Liu Y, Qi LS, Lin MZ ACS chemical biology 28938067 ACS Chem Biol 2018 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/28938067
Optobiology: optical control of biological processes via protein engineering. Kim B, Lin MZ Biochemical Society transactions 24059506 Biochem Soc Trans 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/24059506
Investigating neuronal function with optically controllable proteins. Zhou XX, Pan M, Lin MZ Frontiers in molecular neuroscience 26257603 Front Mol Neurosci 2015 https://www.ncbi.nlm.nih.gov/pubmed/26257603
Optical control of cell signaling by single-chain photoswitchable kinases. Zhou XX, Fan LZ, Li P, Shen K, Lin MZ Science (New York, N.Y.) 28232577 Science 2017 Feb 24 https://www.ncbi.nlm.nih.gov/pubmed/28232577
Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude. Ju J, Lee HN, Ning L, Ryu H, Zhou XX, Chun H, Lee YW, Lee-Richerson AI, Jeong C, Lin MZ, Seong J Cell reports 35830815 Cell Rep 2022 Jul 12 https://www.ncbi.nlm.nih.gov/pubmed/35830815
Fungal polyketide synthase product chain-length control by partnering thiohydrolase. Zabala AO, Chooi YH, Choi MS, Lin HC, Tang Y ACS chemical biology 24845309 ACS Chem Biol 2014 Jul 18 https://www.ncbi.nlm.nih.gov/pubmed/24845309
Short pathways to complexity generation: fungal peptidyl alkaloid multicyclic scaffolds from anthranilate building blocks. Walsh CT, Haynes SW, Ames BD, Gao X, Tang Y ACS chemical biology 23659680 ACS Chem Biol 2013 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/23659680
Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440. Cacho RA, Jiang W, Chooi YH, Walsh CT, Tang Y Journal of the American Chemical Society 22998630 J Am Chem Soc 2012 Oct 10 https://www.ncbi.nlm.nih.gov/pubmed/22998630
Coordinated and Iterative Enzyme Catalysis in Fungal Polyketide Biosynthesis. Hang L, Liu N, Tang Y ACS catalysis 28529817 ACS Catal 2016 Sep 2 https://www.ncbi.nlm.nih.gov/pubmed/28529817
Biosynthesis of Strained Piperazine Alkaloids: Uncovering the Concise Pathway of Herquline A. Yu X, Liu F, Zou Y, Tang MC, Hang L, Houk KN, Tang Y Journal of the American Chemical Society 27690412 J Am Chem Soc 2016 Oct 19 https://www.ncbi.nlm.nih.gov/pubmed/27690412
Involvement of Lipocalin-like CghA in Decalin-Forming Stereoselective Intramolecular [4+2] Cycloaddition. Sato M, Yagishita F, Mino T, Uchiyama N, Patel A, Chooi YH, Goda Y, Xu W, Noguchi H, Yamamoto T, Hotta K, Houk KN, Tang Y, Watanabe K Chembiochem : a European journal of chemical biology 26360642 Chembiochem 2015 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/26360642
Identification and Heterologous Production of a Benzoyl-Primed Tricarboxylic Acid Polyketide Intermediate from the Zaragozic Acid A Biosynthetic Pathway. Liu N, Hung YS, Gao SS, Hang L, Zou Y, Chooi YH, Tang Y Organic letters 28605916 Org Lett 2017 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/28605916
Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway. Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y Journal of the American Chemical Society 24568283 J Am Chem Soc 2014 Mar 19 https://www.ncbi.nlm.nih.gov/pubmed/24568283
Biosynthesis of the α-nitro-containing cyclic tripeptide psychrophilin. Zhao M, Lin HC, Tang Y The Journal of antibiotics 26956794 J Antibiot (Tokyo) 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/26956794
P450-Mediated Coupling of Indole Fragments To Forge Communesin and Unnatural Isomers. Lin HC, McMahon TC, Patel A, Corsello M, Simon A, Xu W, Zhao M, Houk KN, Garg NK, Tang Y Journal of the American Chemical Society 26963294 J Am Chem Soc 2016 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/26963294
Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi. Tang MC, Fischer CR, Chari JV, Tan D, Suresh S, Chu A, Miranda M, Smith J, Zhang Z, Garg NK, St Onge RP, Tang Y Journal of the American Chemical Society 31051070 J Am Chem Soc 2019 May 22 https://www.ncbi.nlm.nih.gov/pubmed/31051070
Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. Yan Y, Liu Q, Zang X, Yuan S, Bat-Erdene U, Nguyen C, Gan J, Zhou J, Jacobsen SE, Tang Y Nature 29995859 Nature 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29995859
Enzymatic one-step ring contraction for quinolone biosynthesis. Kishimoto S, Hara K, Hashimoto H, Hirayama Y, Champagne PA, Houk KN, Tang Y, Watanabe K Nature communications 30026518 Nat Commun 2018 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/30026518
Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases. Sato M, Dander JE, Sato C, Hung YS, Gao SS, Tang MC, Hang L, Winter JM, Garg NK, Watanabe K, Tang Y Journal of the American Chemical Society 28365998 J Am Chem Soc 2017 Apr 19 https://www.ncbi.nlm.nih.gov/pubmed/28365998
SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. Ohashi M, Liu F, Hai Y, Chen M, Tang MC, Yang Z, Sato M, Watanabe K, Houk KN, Tang Y Nature 28902839 Nature 2017 Sep 28 https://www.ncbi.nlm.nih.gov/pubmed/28902839
Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis. Yamamoto T, Tsunematsu Y, Hara K, Suzuki T, Kishimoto S, Kawagishi H, Noguchi H, Hashimoto H, Tang Y, Hotta K, Watanabe K Angewandte Chemie (International ed. in English) 27072782 Angew Chem Int Ed Engl 2016 May 17 https://www.ncbi.nlm.nih.gov/pubmed/27072782
Structural basis of nonribosomal peptide macrocyclization in fungi. Zhang J, Liu N, Cacho RA, Gong Z, Liu Z, Qin W, Tang C, Tang Y, Zhou J Nature chemical biology 27748753 Nat Chem Biol 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27748753
Identification and characterization of the chaetoviridin and chaetomugilin gene cluster in Chaetomium globosum reveal dual functions of an iterative highly-reducing polyketide synthase. Winter JM, Sato M, Sugimoto S, Chiou G, Garg NK, Tang Y, Watanabe K Journal of the American Chemical Society 23072467 J Am Chem Soc 2012 Oct 31 https://www.ncbi.nlm.nih.gov/pubmed/23072467
Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi. Chooi YH, Fang J, Liu H, Filler SG, Wang P, Tang Y Organic letters 23368997 Org Lett 2013 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/23368997
A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis. Chooi YH, Hong YJ, Cacho RA, Tantillo DJ, Tang Y Journal of the American Chemical Society 24161266 J Am Chem Soc 2013 Nov 13 https://www.ncbi.nlm.nih.gov/pubmed/24161266
EcdGHK are three tailoring iron oxygenases for amino acid building blocks of the echinocandin scaffold. Jiang W, Cacho RA, Chiou G, Garg NK, Tang Y, Walsh CT Journal of the American Chemical Society 23451921 J Am Chem Soc 2013 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/23451921
Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. Winter JM, Chiou G, Bothwell IR, Xu W, Garg NK, Luo M, Tang Y Organic letters 23837609 Org Lett 2013 Jul 19 https://www.ncbi.nlm.nih.gov/pubmed/23837609
Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs. Cochrane RV, Gao Z, Lambkin GR, Xu W, Winter JM, Marcus SL, Tang Y, Vederas JC Chembiochem : a European journal of chemical biology 26493380 Chembiochem 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26493380
Saccharomyces cerevisiae as a tool for mining, studying and engineering fungal polyketide synthases. Bond C, Tang Y, Li L Fungal genetics and biology : FG & B 26850128 Fungal Genet Biol 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26850128
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Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids. Li L, Tang MC, Tang S, Gao S, Soliman S, Hang L, Xu W, Ye T, Watanabe K, Tang Y Journal of the American Chemical Society 29373009 J Am Chem Soc 2018 Feb 14 https://www.ncbi.nlm.nih.gov/pubmed/29373009
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Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin. Grandner JM, Cacho RA, Tang Y, Houk KN ACS catalysis 28503354 ACS Catal 2016 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/28503354
Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation. Gao SS, Garcia-Borràs M, Barber JS, Hai Y, Duan A, Garg NK, Houk KN, Tang Y Journal of the American Chemical Society 28240554 J Am Chem Soc 2017 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/28240554
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi. Cacho RA, Tang Y, Chooi YH Frontiers in microbiology 25642215 Front Microbiol 2014 https://www.ncbi.nlm.nih.gov/pubmed/25642215
Elucidation of pseurotin biosynthetic pathway points to trans-acting C-methyltransferase: generation of chemical diversity. Tsunematsu Y, Fukutomi M, Saruwatari T, Noguchi H, Hotta K, Tang Y, Watanabe K Angewandte Chemie (International ed. in English) 24939566 Angew Chem Int Ed Engl 2014 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/24939566
Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products. Mao XM, Xu W, Li D, Yin WB, Chooi YH, Li YQ, Tang Y, Hu Y Angewandte Chemie (International ed. in English) 26013262 Angew Chem Int Ed Engl 2015 Jun 22 https://www.ncbi.nlm.nih.gov/pubmed/26013262
Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin. Cacho RA, Chooi YH, Zhou H, Tang Y ACS chemical biology 23978092 ACS Chem Biol 2013 Oct 18 https://www.ncbi.nlm.nih.gov/pubmed/23978092
The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus. Dhingra S, Lind AL, Lin HC, Tang Y, Rokas A, Calvo AM PloS one 24116213 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/24116213
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Systems-wide Studies Uncover Commander, a Multiprotein Complex Essential to Human Development. Mallam AL, Marcotte EM Cell systems 28544880 Cell Syst 2017 May 24 https://www.ncbi.nlm.nih.gov/pubmed/28544880
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Long-term neural and physiological phenotyping of a single human. Poldrack RA, Laumann TO, Koyejo O, Gregory B, Hover A, Chen MY, Gorgolewski KJ, Luci J, Joo SJ, Boyd RL, Hunicke-Smith S, Simpson ZB, Caven T, Sochat V, Shine JM, Gordon E, Snyder AZ, Adeyemo B, Petersen SE, Glahn DC, Reese Mckay D, Curran JE, Göring HH, Carless MA, Blangero J, Dougherty R, Leemans A, Handwerker DA, Frick L, Marcotte EM, Mumford JA Nature communications 26648521 Nat Commun 2015 Dec 9 https://www.ncbi.nlm.nih.gov/pubmed/26648521
Solution-phase and solid-phase sequential, selective modification of side chains in KDYWEC and KDYWE as models for usage in single-molecule protein sequencing. Hernandez ET, Swaminathan J, Marcotte EM, Anslyn EV New journal of chemistry = Nouveau journal de chimie 28983186 New J Chem 2017 Jan 21 https://www.ncbi.nlm.nih.gov/pubmed/28983186
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The proteomic response to mutants of the Escherichia coli RNA degradosome. Zhou L, Zhang AB, Wang R, Marcotte EM, Vogel C Molecular bioSystems 23403814 Mol Biosyst 2013 Apr 5 https://www.ncbi.nlm.nih.gov/pubmed/23403814
Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Vogel C, Marcotte EM Nature reviews. Genetics 22411467 Nat Rev Genet 2012 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/22411467
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Metabolic crosstalk regulates Porphyromonas gingivalis colonization and virulence during oral polymicrobial infection. Kuboniwa M, Houser JR, Hendrickson EL, Wang Q, Alghamdi SA, Sakanaka A, Miller DP, Hutcherson JA, Wang T, Beck DAC, Whiteley M, Amano A, Wang H, Marcotte EM, Hackett M, Lamont RJ Nature microbiology 28924191 Nat Microbiol 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/28924191
An efficient methodology to introduce o-(aminomethyl)phenyl-boronic acids into peptides: alkylation of secondary amines. Hernandez ET, Kolesnichenko IV, Reuther JF, Anslyn EV New journal of chemistry = Nouveau journal de chimie 28649175 New J Chem 2017 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/28649175
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Photography Coupled with Self-Propagating Chemical Cascades: Differentiation and Quantitation of G- and V-Nerve Agent Mimics via Chromaticity. Sun X, Boulgakov AA, Smith LN, Metola P, Marcotte EM, Anslyn EV ACS central science 30062113 ACS Cent Sci 2018 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/30062113
The DEAH-box helicase Dhr1 dissociates U3 from the pre-rRNA to promote formation of the central pseudoknot. Sardana R, Liu X, Granneman S, Zhu J, Gill M, Papoulas O, Marcotte EM, Tollervey D, Correll CC, Johnson AW PLoS biology 25710520 PLoS Biol 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25710520
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Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness. Hammerling MJ, Ellefson JW, Boutz DR, Marcotte EM, Ellington AD, Barrick JE Nature chemical biology 24487692 Nat Chem Biol 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24487692
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Diversity of human tRNA genes from the 1000-genomes project. Parisien M, Wang X, Pan T RNA biology 24448271 RNA Biol 2013 Dec https://www.ncbi.nlm.nih.gov/pubmed/24448271
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Modifications and functional genomics of human transfer RNA. Pan T Cell research 29463900 Cell Res 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29463900
tRNA Misacylation with Methionine in the Mouse Gut Microbiome in Situ. Schwartz MH, Pan T Microbial ecology 28070678 Microb Ecol 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28070678
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Adaptive translation as a mechanism of stress response and adaptation. Pan T Annual review of genetics 23988117 Annu Rev Genet 2013 https://www.ncbi.nlm.nih.gov/pubmed/23988117
Efficient and quantitative high-throughput tRNA sequencing. Zheng G, Qin Y, Clark WC, Dai Q, Yi C, He C, Lambowitz AM, Pan T Nature methods 26214130 Nat Methods 2015 Sep https://www.ncbi.nlm.nih.gov/pubmed/26214130
Stress Response and Adaptation Mediated by Amino Acid Misincorporation during Protein Synthesis. Wang X, Pan T Advances in nutrition (Bethesda, Md.) 27422514 Adv Nutr 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27422514
Determining the fidelity of tRNA aminoacylation via microarrays. Schwartz MH, Pan T Methods (San Diego, Calif.) 27639882 Methods 2017 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/27639882
tRNA base methylation identification and quantification via high-throughput sequencing. Clark WC, Evans ME, Dominissini D, Zheng G, Pan T RNA (New York, N.Y.) 27613580 RNA 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27613580
Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair. Sun L, Gomes AC, He W, Zhou H, Wang X, Pan DW, Schimmel P, Pan T, Yang XL Journal of the American Chemical Society 27622773 J Am Chem Soc 2016 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/27622773
Global tRNA misacylation induced by anaerobiosis and antibiotic exposure broadly increases stress resistance in Escherichia coli. Schwartz MH, Waldbauer JR, Zhang L, Pan T Nucleic acids research 27672035 Nucleic Acids Res 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27672035
Interaction of tRNA with MEK2 in pancreatic cancer cells. Wang X, Chow CR, Ebine K, Lee J, Rosner MR, Pan T, Munshi HG Scientific reports 27301426 Sci Rep 2016 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/27301426
Temperature dependent mistranslation in a hyperthermophile adapts proteins to lower temperatures. Schwartz MH, Pan T Nucleic acids research 26657639 Nucleic Acids Res 2016 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/26657639
My adventure in tRNA biology, so far. Pan T RNA (New York, N.Y.) 25780201 RNA 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25780201
Selective Enzymatic Demethylation of N(2) ,N(2) -Dimethylguanosine in RNA and Its Application in High-Throughput tRNA Sequencing. Dai Q, Zheng G, Schwartz MH, Clark WC, Pan T Angewandte Chemie (International ed. in English) 28371071 Angew Chem Int Ed Engl 2017 Apr 24 https://www.ncbi.nlm.nih.gov/pubmed/28371071
Codon optimality controls differential mRNA translation during amino acid starvation. Saikia M, Wang X, Mao Y, Wan J, Pan T, Qian SB RNA (New York, N.Y.) 27613579 RNA 2016 Nov https://www.ncbi.nlm.nih.gov/pubmed/27613579
N(6)-Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding. Zhou KI, Parisien M, Dai Q, Liu N, Diatchenko L, Sachleben JR, Pan T Journal of molecular biology 26343757 J Mol Biol 2016 Feb 27 https://www.ncbi.nlm.nih.gov/pubmed/26343757
A dual fluorescent reporter for the investigation of methionine mistranslation in live cells. Gomes AC, Kordala AJ, Strack R, Wang X, Geslain R, Delaney K, Clark WC, Keenan R, Pan T RNA (New York, N.Y.) 26729921 RNA 2016 Mar https://www.ncbi.nlm.nih.gov/pubmed/26729921
Methionine Mistranslation Bypasses the Restraint of the Genetic Code to Generate Mutant Proteins with Distinct Activities. Wang X, Pan T PLoS genetics 26709516 PLoS Genet 2015 Dec https://www.ncbi.nlm.nih.gov/pubmed/26709516
Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3. Fry MY, Najdrová V, Maggiolo AO, Saladi SM, Doležal P, Clemons WM Jr Nature structural & molecular biology 35851188 Nat Struct Mol Biol 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/35851188
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Two-Color Volumetric Imaging of Neuronal Activity of Cortical Columns. Han S, Yang W, Yuste R Cell reports 31091458 Cell Rep 2019 May 14 https://www.ncbi.nlm.nih.gov/pubmed/31091458
Reduced Repertoire of Cortical Microstates and Neuronal Ensembles in Medically Induced Loss of Consciousness. Wenzel M, Han S, Smith EH, Hoel E, Greger B, House PA, Yuste R Cell systems 31054810 Cell Syst 2019 May 22 https://www.ncbi.nlm.nih.gov/pubmed/31054810
Controlling Visually Guided Behavior by Holographic Recalling of Cortical Ensembles. Carrillo-Reid L, Han S, Yang W, Akrouh A, Yuste R Cell 31257030 Cell 2019 Jul 11 https://www.ncbi.nlm.nih.gov/pubmed/31257030
Simultaneous two-photon imaging and two-photon optogenetics of cortical circuits in three dimensions. Yang W, Carrillo-Reid L, Bando Y, Peterka DS, Yuste R eLife 29412138 Elife 2018 Feb 7 https://www.ncbi.nlm.nih.gov/pubmed/29412138
Multi-scale approaches for high-speed imaging and analysis of large neural populations. Friedrich J, Yang W, Soudry D, Mu Y, Ahrens MB, Yuste R, Peterka DS, Paninski L PLoS computational biology 28771570 PLoS Comput Biol 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28771570
Parvalbumin-Positive Interneurons Regulate Neuronal Ensembles in Visual Cortex. Agetsuma M, Hamm JP, Tao K, Fujisawa S, Yuste R Cerebral cortex (New York, N.Y. : 1991) 29106504 Cereb Cortex 2018 May 1 https://www.ncbi.nlm.nih.gov/pubmed/29106504
fMRI of retina-originated phosphenes experienced by patients with Leber congenital amaurosis. Ashtari M, Cyckowski L, Yazdi A, Viands A, Marshall K, Bókkon I, Maguire A, Bennett J PloS one 24465873 PLoS One 2014 https://www.ncbi.nlm.nih.gov/pubmed/24465873
Differential targeting of feline photoreceptors by recombinant adeno-associated viral vectors: implications for preclinical gene therapy trials. Minella AL, Mowat FM, Willett KL, Sledge D, Bartoe JT, Bennett J, Petersen-Jones SM Gene therapy 25056608 Gene Ther 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25056608
Institutional Conflict of Interest. Bennett J JAMA ophthalmology 27583791 JAMA Ophthalmol 2016 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/27583791
Single stranded adeno-associated virus achieves efficient gene transfer to anterior segment in the mouse eye. Wang L, Xiao R, Andres-Mateos E, Vandenberghe LH PloS one 28763501 PLoS One 2017 https://www.ncbi.nlm.nih.gov/pubmed/28763501
Evaluating Efficiencies of Dual AAV Approaches for Retinal Targeting. Carvalho LS, Turunen HT, Wassmer SJ, Luna-Velez MV, Xiao R, Bennett J, Vandenberghe LH Frontiers in neuroscience 28943836 Front Neurosci 2017 https://www.ncbi.nlm.nih.gov/pubmed/28943836
Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection. Wassmer SJ, Carvalho LS, György B, Vandenberghe LH, Maguire CA Scientific reports 28361998 Sci Rep 2017 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/28361998
Taking Stock of Retinal Gene Therapy: Looking Back and Moving Forward. Bennett J Molecular therapy : the journal of the American Society of Gene Therapy 28391961 Mol Ther 2017 May 3 https://www.ncbi.nlm.nih.gov/pubmed/28391961
Gene Therapy and Stem Cell Transplantation in Retinal Disease: The New Frontier. MacLaren RE, Bennett J, Schwartz SD Ophthalmology 27664291 Ophthalmology 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27664291
Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial. Bennett J, Wellman J, Marshall KA, McCague S, Ashtari M, DiStefano-Pappas J, Elci OU, Chung DC, Sun J, Wright JF, Cross DR, Aravand P, Cyckowski LL, Bennicelli JL, Mingozzi F, Auricchio A, Pierce EA, Ruggiero J, Leroy BP, Simonelli F, High KA, Maguire AM Lancet (London, England) 27375040 Lancet 2016 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/27375040
Evaluation of Dose and Safety of AAV7m8 and AAV8BP2 in the Non-Human Primate Retina. Ramachandran PS, Lee V, Wei Z, Song JY, Casal G, Cronin T, Willett K, Huckfeldt R, Morgan JI, Aleman TS, Maguire AM, Bennett J Human gene therapy 27750461 Hum Gene Ther 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/27750461
Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. Drivas TG, Holzbaur EL, Bennett J The Journal of clinical investigation 24051377 J Clin Invest 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/24051377
AAV2.7m8 is a powerful viral vector for inner ear gene therapy. Isgrig K, McDougald DS, Zhu J, Wang HJ, Bennett J, Chien WW Nature communications 30683875 Nat Commun 2019 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/30683875
An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications. Sochor MA, Vasireddy V, Drivas TG, Wojno A, Doung T, Shpylchak I, Bennicelli J, Chung D, Bennett J, Lewis M Scientific reports 26597678 Sci Rep 2015 Nov 24 https://www.ncbi.nlm.nih.gov/pubmed/26597678
Synthetic Adeno-Associated Viral Vector Efficiently Targets Mouse and Nonhuman Primate Retina In Vivo. Carvalho LS, Xiao R, Wassmer SJ, Langsdorf A, Zinn E, Pacouret S, Shah S, Comander JI, Kim LA, Lim L, Vandenberghe LH Human gene therapy 29325457 Hum Gene Ther 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29325457
Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c. Pan B, Askew C, Galvin A, Heman-Ackah S, Asai Y, Indzhykulian AA, Jodelka FM, Hastings ML, Lentz JJ, Vandenberghe LH, Holt JR, Géléoc GS Nature biotechnology 28165476 Nat Biotechnol 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28165476
Progress in gene therapy for neurological disorders. Simonato M, Bennett J, Boulis NM, Castro MG, Fink DJ, Goins WF, Gray SJ, Lowenstein PR, Vandenberghe LH, Wilson TJ, Wolfe JH, Glorioso JC Nature reviews. Neurology 23609618 Nat Rev Neurol 2013 May https://www.ncbi.nlm.nih.gov/pubmed/23609618
AAV8BP2 and AAV8 transduce the mammalian cochlear lateral wall and endolymphatic sac with high efficiency. Isgrig K, Ishibashi Y, Lee HJ, Zhu J, Grati M, Bennett J, Griffith AJ, Roux I, Chien WW Molecular therapy. Methods & clinical development 36034771 Mol Ther Methods Clin Dev 2022 Sep 8 https://www.ncbi.nlm.nih.gov/pubmed/36034771
Immunology of AAV-Mediated Gene Transfer in the Eye. Willett K, Bennett J Frontiers in immunology 24009613 Front Immunol 2013 https://www.ncbi.nlm.nih.gov/pubmed/24009613
Plasticity of the human visual system after retinal gene therapy in patients with Leber's congenital amaurosis. Ashtari M, Zhang H, Cook PA, Cyckowski LL, Shindler KS, Marshall KA, Aravand P, Vossough A, Gee JC, Maguire AM, Baker CI, Bennett J Science translational medicine 26180100 Sci Transl Med 2015 Jul 15 https://www.ncbi.nlm.nih.gov/pubmed/26180100
Exploiting metabolic and antioxidant pathways to maintain vision in blinding disease. Ramachandran PS, Song JY, Bennett J The Journal of clinical investigation 25798615 J Clin Invest 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25798615
Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial. Russell S, Bennett J, Wellman JA, Chung DC, Yu ZF, Tillman A, Wittes J, Pappas J, Elci O, McCague S, Cross D, Marshall KA, Walshire J, Kehoe TL, Reichert H, Davis M, Raffini L, George LA, Hudson FP, Dingfield L, Zhu X, Haller JA, Sohn EH, Mahajan VB, Pfeifer W, Weckmann M, Johnson C, Gewaily D, Drack A, Stone E, Wachtel K, Simonelli F, Leroy BP, Wright JF, High KA, Maguire AM Lancet (London, England) 28712537 Lancet 2017 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/28712537
Refining surgical techniques for efficient posterior semicircular canal gene delivery in the adult mammalian inner ear with minimal hearing loss. Zhu J, Choi JW, Ishibashi Y, Isgrig K, Grati M, Bennett J, Chien W Scientific reports 34552193 Sci Rep 2021 Sep 22 https://www.ncbi.nlm.nih.gov/pubmed/34552193
Amelioration of Neurosensory Structure and Function in Animal and Cellular Models of a Congenital Blindness. Song JY, Aravand P, Nikonov S, Leo L, Lyubarsky A, Bennicelli JL, Pan J, Wei Z, Shpylchak I, Herrera P, Bennett DJ, Commins N, Maguire AM, Pham J, den Hollander AI, Cremers FPM, Koenekoop RK, Roepman R, Nishina P, Zhou S, Pan W, Ying GS, Aleman TS, de Melo J, McNamara I, Sun J, Mills J, Bennett J Molecular therapy : the journal of the American Society of Gene Therapy 29673930 Mol Ther 2018 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/29673930
Novel mobility test to assess functional vision in patients with inherited retinal dystrophies. Chung DC, McCague S, Yu ZF, Thill S, DiStefano-Pappas J, Bennett J, Cross D, Marshall K, Wellman J, High KA Clinical & experimental ophthalmology 28697537 Clin Exp Ophthalmol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/28697537
State dependence of noise correlations in macaque primary visual cortex. Ecker AS, Berens P, Cotton RJ, Subramaniyan M, Denfield GH, Cadwell CR, Smirnakis SM, Bethge M, Tolias AS Neuron 24698278 Neuron 2014 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/24698278
Community-based benchmarking improves spike rate inference from two-photon calcium imaging data. Berens P, Freeman J, Deneux T, Chenkov N, McColgan T, Speiser A, Macke JH, Turaga SC, Mineault P, Rupprecht P, Gerhard S, Friedrich RW, Friedrich J, Paninski L, Pachitariu M, Harris KD, Bolte B, Machado TA, Ringach D, Stone J, Rogerson LE, Sofroniew NJ, Reimer J, Froudarakis E, Euler T, Román Rosón M, Theis L, Tolias AS, Bethge M PLoS computational biology 29782491 PLoS Comput Biol 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29782491
Integrated Neurophotonics: Toward Dense Volumetric Interrogation of Brain Circuit Activity-at Depth and in Real Time. Moreaux LC, Yatsenko D, Sacher WD, Choi J, Lee C, Kubat NJ, Cotton RJ, Boyden ES, Lin MZ, Tian L, Tolias AS, Poon JKS, Shepard KL, Roukes ML Neuron 33058767 Neuron 2020 Oct 14 https://www.ncbi.nlm.nih.gov/pubmed/33058767
Developmental broadening of inhibitory sensory maps. Quast KB, Ung K, Froudarakis E, Huang L, Herman I, Addison AP, Ortiz-Guzman J, Cordiner K, Saggau P, Tolias AS, Arenkiel BR Nature neuroscience 28024159 Nat Neurosci 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/28024159
Spike sorting for large, dense electrode arrays. Rossant C, Kadir SN, Goodman DFM, Schulman J, Hunter MLD, Saleem AB, Grosmark A, Belluscio M, Denfield GH, Ecker AS, Tolias AS, Solomon S, Buzsaki G, Carandini M, Harris KD Nature neuroscience 26974951 Nat Neurosci 2016 Apr https://www.ncbi.nlm.nih.gov/pubmed/26974951
Macaque monkeys perceive the flash lag illusion. Subramaniyan M, Ecker AS, Berens P, Tolias AS PloS one 23527024 PLoS One 2013 https://www.ncbi.nlm.nih.gov/pubmed/23527024
The effect of noise correlations in populations of diversely tuned neurons. Ecker AS, Berens P, Tolias AS, Bethge M The Journal of neuroscience : the official journal of the Society for Neuroscience 21976512 J Neurosci 2011 Oct 5 https://www.ncbi.nlm.nih.gov/pubmed/21976512
A neural basis of probabilistic computation in visual cortex. Walker EY, Cotton RJ, Ma WJ, Tolias AS Nature neuroscience 31873286 Nat Neurosci 2020 Jan https://www.ncbi.nlm.nih.gov/pubmed/31873286
Three-dimensional mapping of microcircuit correlation structure. Cotton RJ, Froudarakis E, Storer P, Saggau P, Tolias AS Frontiers in neural circuits 24133414 Front Neural Circuits 2013 https://www.ncbi.nlm.nih.gov/pubmed/24133414
Structural, interpersonal, psychosocial, and behavioral risk factors for HIV acquisition among female bar workers in Dar es Salaam, Tanzania. Barnhart DA, Harling G, Muya A, Ortblad KF, Mashasi I, Dambach P, Ulenga N, Mboggo E, Oldenburg CE, Bärnighausen TW, Spiegelman D AIDS care 31079476 AIDS Care 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31079476
Augmented pseudo-likelihood estimation for two-phase studies. Rivera-Rodriguez C, Haneuse S, Wang M, Spiegelman D Statistical methods in medical research 30834815 Stat Methods Med Res 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/30834815
Spiegelman and Zhou Respond. Spiegelman D, Zhou X American journal of public health 30726133 Am J Public Health 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30726133
Partial Identification of the Average Treatment Effect Using Instrumental Variables: Review of Methods for Binary Instruments, Treatments, and Outcomes. Swanson SA, Hernán MA, Miller M, Robins JM, Richardson TS Journal of the American Statistical Association 31537952 J Am Stat Assoc 2018 https://www.ncbi.nlm.nih.gov/pubmed/31537952
Multiple robust estimation of marginal structural mean models for unconstrained outcomes. Babino L, Rotnitzky A, Robins J Biometrics 30004573 Biometrics 2019 Mar https://www.ncbi.nlm.nih.gov/pubmed/30004573
Assessing Individual and Disseminated Effects in Network-Randomized Studies. Buchanan AL, Vermund SH, Friedman SR, Spiegelman D American journal of epidemiology 30052722 Am J Epidemiol 2018 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/30052722
Access of choice-disabled young women in Botswana to government structural support programmes: a cross-sectional study. Cockcroft A, Marokoane N, Kgakole L, Tswetla N, Andersson N AIDS care 29848044 AIDS Care 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29848044
The effect of risk factor misclassification on the partial population attributable risk. Wong BHW, Peskoe SB, Spiegelman D Statistics in medicine 29333614 Stat Med 2018 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/29333614
Estimation and Inference for the Mediation Proportion. Nevo D, Liao X, Spiegelman D The international journal of biostatistics 28930628 Int J Biostat 2017 Sep 20 https://www.ncbi.nlm.nih.gov/pubmed/28930628
Prevalence estimation when disease status is verified only among test positives: Applications in HIV screening programs. G Thomas E, B Peskoe S, Spiegelman D Statistics in medicine 29230839 Stat Med 2018 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/29230839
The Association of Cooking Fuel Use, Dietary Intake, and Blood Pressure among Rural Women in China. Bellows AL, Spiegelman D, Du S, Jaacks LM International journal of environmental research and public health 32751678 Int J Environ Res Public Health 2020 Jul 30 https://www.ncbi.nlm.nih.gov/pubmed/32751678
Worksite intervention study to prevent diabetes in Nepal: a randomised trial protocol. Pyakurel P, Shrestha A, Karmacharya BM, Budhathoki SS, Chaudhari RK, Tamrakar D, Shrestha A, Karmacharya RM, Shrestha A, Sharma S, Sharma SK, Spiegelman D Open heart 32847993 Open Heart 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32847993
Coaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Uttar Pradesh, India. Barnhart DA, Spiegelman D, Zigler CM, Kara N, Delaney MM, Kalita T, Maji P, Hirschhorn LR, Semrau KEA Global health, science and practice 32127359 Glob Health Sci Pract 2020 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/32127359
Evaluating Public Health Interventions: 6. Modeling Ratios or Differences? Let the Data Tell Us. Spiegelman D, VanderWeele TJ American journal of public health 28590865 Am J Public Health 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28590865
Evaluating Public Health Interventions: 1. Examples, Definitions, and a Personal Note. Spiegelman D American journal of public health 26562122 Am J Public Health 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/26562122
Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality. Lee C, Kushi LH, Reed ME, Eldridge EH, Lee JK, Zhang J, Spiegelman D American journal of preventive medicine 34763959 Am J Prev Med 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/34763959
Estimating the natural indirect effect and the mediation proportion via the product method. Cheng C, Spiegelman D, Li F BMC medical research methodology 34800985 BMC Med Res Methodol 2021 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/34800985
Assessing Direct and Spillover Effects of Intervention Packages in Network-Randomized Studies. Buchanan AL, Hernández-Ramírez RU, Lok JJ, Vermund SH, Friedman SR, Forastiere L, Spiegelman D medRxiv : the preprint server for health sciences 38352598 medRxiv 2024 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/38352598
Dietary interventions to prevent and manage diabetes in worksite settings: a meta-analysis. Shrestha A, Karmacharya BM, Khudyakov P, Weber MB, Spiegelman D Journal of occupational health 29187673 J Occup Health 2018 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/29187673
Spiegelman Responds. Spiegelman D American journal of public health 27153027 Am J Public Health 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/27153027
Evaluating Public Health Interventions: 5. Causal Inference in Public Health Research-Do Sex, Race, and Biological Factors Cause Health Outcomes? Glymour MM, Spiegelman D American journal of public health 27854526 Am J Public Health 2017 Jan https://www.ncbi.nlm.nih.gov/pubmed/27854526
Evaluating Public Health Interventions: 4. The Nurses' Health Study and Methods for Eliminating Bias Attributable to Measurement Error and Misclassification. Spiegelman D American journal of public health 27509282 Am J Public Health 2016 Sep https://www.ncbi.nlm.nih.gov/pubmed/27509282
Evaluating Public Health Interventions: 3. The Two-Stage Design for Confounding Bias Reduction-Having Your Cake and Eating It Two. Spiegelman D, Rivera-Rodriguez CL, Haneuse S American journal of public health 27285260 Am J Public Health 2016 Jul https://www.ncbi.nlm.nih.gov/pubmed/27285260
A note on "Design and analysis of stepped wedge cluster randomized trials". Liao X, Zhou X, Spiegelman D Contemporary clinical trials 26394003 Contemp Clin Trials 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26394003
How are qualitative methods used in implementation science research? A scoping review protocol. Hagaman A, Rhodes EC, Nyhan K, Katague M, Schwartz A, Spiegelman D JBI evidence synthesis 33323772 JBI Evid Synth 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33323772
Assessing the quality of tuberculosis care using routine surveillance data: a process evaluation employing the Zero TB Indicator Framework in Mongolia. Saranjav A, Parisi C, Zhou X, Dorjnamjil K, Samdan T, Erdenebaatar S, Chuluun A, Dalkh T, Ganbaatar G, Brooks MB, Spiegelman D, Ganmaa D, Davis JL BMJ open 35973702 BMJ Open 2022 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/35973702
The fidelity of implementation of recommended care for children with malaria by community health workers in Nigeria. Adeoti O, Spiegelman D, Afonne C, Falade CO, Jegede AS, Oshiname FO, Gomes M, Ajayi IO Implementation science : IS 32131852 Implement Sci 2020 Mar 4 https://www.ncbi.nlm.nih.gov/pubmed/32131852
Optimizing the development and evaluation of complex interventions: lessons learned from the BetterBirth Program and associated trial. Barnhart DA, Semrau KEA, Zigler CM, Molina RL, Delaney MM, Hirschhorn LR, Spiegelman D Implementation science communications 32885188 Implement Sci Commun 2020 https://www.ncbi.nlm.nih.gov/pubmed/32885188
Estimation in the Cox survival regression model with covariate measurement error and a changepoint. Agami S, Zucker DM, Spiegelman D Biometrical journal. Biometrische Zeitschrift 32003495 Biom J 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/32003495
Impact of the Affordable Care Act on Colorectal Cancer Outcomes: A Systematic Review. Xu MR, Kelly AMB, Kushi LH, Reed ME, Koh HK, Spiegelman D American journal of preventive medicine 32008799 Am J Prev Med 2020 Apr https://www.ncbi.nlm.nih.gov/pubmed/32008799
Nepal Pioneer Worksite Intervention Study to lower cardio-metabolic risk factors: design and protocol. Shrestha A, Tamrakar D, Karmacharya BM, Shrestha A, Shrestha R, Bhatta RD, Pyakurel P, Khudyakov P, Malik V, Mattei J, Spiegelman D BMC cardiovascular disorders 30819098 BMC Cardiovasc Disord 2019 Feb 28 https://www.ncbi.nlm.nih.gov/pubmed/30819098
Facilitators and barriers to healthy eating in a worksite cafeteria: a qualitative study. Stern D, Blanco I, Olmos LA, Valdivia JJ, Shrestha A, Mattei J, Spiegelman D BMC public health 34022846 BMC Public Health 2021 May 22 https://www.ncbi.nlm.nih.gov/pubmed/34022846
There is no impact of exposure measurement error on latency estimation in linear models. Peskoe SB, Spiegelman D, Wang M Statistics in medicine 30515870 Stat Med 2019 Mar 30 https://www.ncbi.nlm.nih.gov/pubmed/30515870
On the Analysis of Case-Control Studies in Cluster-correlated Data Settings. Haneuse S, Rivera-Rodriguez C Epidemiology (Cambridge, Mass.) 29068840 Epidemiology 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29068840
Correcting for bias due to mismeasured exposure in mediation analysis with a survival outcome. Cheng C, Spiegelman D, Li F Journal of the Royal Statistical Society. Series C, Applied statistics 40837827 J R Stat Soc Ser C Appl Stat 2025 Nov https://www.ncbi.nlm.nih.gov/pubmed/40837827
Intra-Cluster Correlation Estimates for HIV-related Outcomes from Care and Treatment Clinics in Dar es Salaam, Tanzania. Barnhart D, Hertzmark E, Liu E, Mungure E, Muya AN, Sando D, Chalamilla G, Ulenga N, Bärnighausen T, Fawzi W, Spiegelman D Contemporary clinical trials communications 27766318 Contemp Clin Trials Commun 2016 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/27766318
Evaluating Public Health Interventions: 7. Let the Subject Matter Choose the Effect Measure: Ratio, Difference, or Something Else Entirely. Spiegelman D, Khudyakov P, Wang M, Vanderweele TJ American journal of public health 29161073 Am J Public Health 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29161073
Survival analysis with functions of mismeasured covariate histories: the case of chronic air pollution exposure in relation to mortality in the nurses' health study. Liao X, Zhou X, Wang M, Hart JE, Laden F, Spiegelman D Journal of the Royal Statistical Society. Series C, Applied statistics 29430064 J R Stat Soc Ser C Appl Stat 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29430064
Service readiness of health facilities in Bangladesh, Haiti, Kenya, Malawi, Namibia, Nepal, Rwanda, Senegal, Uganda and the United Republic of Tanzania. Leslie HH, Spiegelman D, Zhou X, Kruk ME Bulletin of the World Health Organization 29147054 Bull World Health Organ 2017 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/29147054
A maximum likelihood approach to power calculations for stepped wedge designs of binary outcomes. Zhou X, Liao X, Kunz LM, Normand ST, Wang M, Spiegelman D Biostatistics (Oxford, England) 30084949 Biostatistics 2020 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/30084949
Health system measurement: Harnessing machine learning to advance global health. Leslie HH, Zhou X, Spiegelman D, Kruk ME PloS one 30289935 PLoS One 2018 https://www.ncbi.nlm.nih.gov/pubmed/30289935
On the analysis of two-phase designs in cluster-correlated data settings. Rivera-Rodriguez C, Spiegelman D, Haneuse S Statistics in medicine 31359448 Stat Med 2019 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/31359448
Association of the US President's Emergency Plan for AIDS Relief's Funding With Prevention of Mother-to-Child Transmission of HIV in Kenya. Barnhart DA, Tsikhutsu I, Kirui D, Sawe F, Muli J, Sugut W, Abboud N, Birx D, Hamm T, Coakley P, Hickey PW, Wolfman V, Lee E, Spiegelman D JAMA network open 31517966 JAMA Netw Open 2019 Sep 4 https://www.ncbi.nlm.nih.gov/pubmed/31517966
Comparison of HPV-16 and HPV-18 Genotyping and Cytological Testing as Triage Testing Within Human Papillomavirus-Based Screening in Mexico. Torres-Ibarra L, Cuzick J, Lorincz AT, Spiegelman D, Lazcano-Ponce E, Franco EL, Moscicki AB, Mahmud SM, Wheeler CM, Rivera-Paredez B, Hernández-López R, León-Maldonado L, Salmerón J, FRIDA Study Group. JAMA network open 31747033 JAMA Netw Open 2019 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/31747033
Drivers of healthy eating in a workplace in Nepal: a qualitative study. Tamrakar D, Shrestha A, Rai A, Karmacharya BM, Malik V, Mattei J, Spiegelman D BMJ open 32102804 BMJ Open 2020 Feb 25 https://www.ncbi.nlm.nih.gov/pubmed/32102804
Exposure misclassification in propensity score-based time-to-event data analysis. Yang Y, Wang M Statistical methods in medical research 33826453 Stat Methods Med Res 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33826453
ANALYSIS OF "LEARN-AS-YOU-GO" (LAGO) STUDIES. Nevo D, Lok JJ, Spiegelman D Annals of statistics 35510045 Ann Stat 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/35510045
swdpwr: A SAS macro and an R package for power calculations in stepped wedge cluster randomized trials. Chen J, Zhou X, Li F, Spiegelman D Computer methods and programs in biomedicine 34818620 Comput Methods Programs Biomed 2022 Jan https://www.ncbi.nlm.nih.gov/pubmed/34818620
Mediation analysis in the presence of continuous exposure measurement error. Cheng C, Spiegelman D, Li F Statistics in medicine 36869626 Stat Med 2023 May 20 https://www.ncbi.nlm.nih.gov/pubmed/36869626
Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies. Buchanan AL, Hernández-Ramírez RU, Lok JJ, Vermund SH, Friedman SR, Forastiere L, Spiegelman D Epidemiology (Cambridge, Mass.) 38709023 Epidemiology 2024 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/38709023
Effects of a dietary intervention on cardiometabolic risk and food consumption in a workplace. Shrestha A, Tamrakar D, Ghinanju B, Shrestha D, Khadka P, Adhikari B, Shrestha J, Waiwa S, Pyakurel P, Bhandari N, Karmacharya BM, Shrestha A, Shrestha R, Bhatta RD, Malik V, Mattei J, Spiegelman D PloS one 38656951 PLoS One 2024 https://www.ncbi.nlm.nih.gov/pubmed/38656951
Evaluating Public Health Interventions: 2. Stepping Up to Routine Public Health Evaluation With the Stepped Wedge Design. Spiegelman D American journal of public health 26885961 Am J Public Health 2016 Mar https://www.ncbi.nlm.nih.gov/pubmed/26885961
"Cross-sectional" stepped wedge designs always reduce the required sample size when there is no time effect. Zhou X, Liao X, Spiegelman D Journal of clinical epidemiology 28093263 J Clin Epidemiol 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28093263
Diet and Health - What Should We Eat ? Shrestha A, Spiegelman D Kathmandu University medical journal (KUMJ) 30353891 Kathmandu Univ Med J (KUMJ) 2017 Jul-Sept. https://www.ncbi.nlm.nih.gov/pubmed/30353891
Evaluating Public Health Interventions: 8. Causal Inference for Time-Invariant Interventions. Spiegelman D, Zhou X American journal of public health 30024804 Am J Public Health 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30024804
Inverse probability weighted estimation of risk under representative interventions in observational studies. Young JG, Logan RW, Robins JM, Hernán MA Journal of the American Statistical Association 31564760 J Am Stat Assoc 2019 https://www.ncbi.nlm.nih.gov/pubmed/31564760
Facilitators and barriers to healthy eating in a worksite cafeteria: a qualitative study from Nepal. Shrestha A, Pyakurel P, Shrestha A, Gautam R, Manandhar N, Rhodes E, Tamrakar D, Karmacharya BM, Malik V, Mattei J, Spiegelman D Heart Asia 29225703 Heart Asia 2017 https://www.ncbi.nlm.nih.gov/pubmed/29225703
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Encrypted Three-dimensional Dynamic Imaging using Snapshot Time-of-flight Compressed Ultrafast Photography. Liang J, Gao L, Hai P, Li C, Wang LV Scientific reports 26503834 Sci Rep 2015 Oct 27 https://www.ncbi.nlm.nih.gov/pubmed/26503834
Dual-Modality Photoacoustic and Ultrasound Imaging System for Noninvasive Sentinel Lymph Node Detection in Patients with Breast Cancer. Garcia-Uribe A, Erpelding TN, Krumholz A, Ke H, Maslov K, Appleton C, Margenthaler JA, Wang LV Scientific reports 26510774 Sci Rep 2015 Oct 29 https://www.ncbi.nlm.nih.gov/pubmed/26510774
Time-reversed ultrasonically encoded optical focusing through highly scattering ex vivo human cataractous lenses. Liu Y, Shen Y, Ruan H, Brodie FL, Wong TTW, Yang C, Wang LV Journal of biomedical optics 29322749 J Biomed Opt 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29322749
Recent progress in photoacoustic molecular imaging. Yao J, Wang LV Current opinion in chemical biology 29631120 Curr Opin Chem Biol 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29631120
Label-free cell nuclear imaging by Grüneisen relaxation photoacoustic microscopy. Liu X, Wong TTW, Shi J, Ma J, Yang Q, Wang LV Optics letters 29444034 Opt Lett 2018 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/29444034
Wide-field two-dimensional multifocal optical-resolution photoacoustic-computed microscopy. Xia J, Li G, Wang L, Nasiriavanaki M, Maslov K, Engelbach JA, Garbow JR, Wang LV Optics letters 24322226 Opt Lett 2013 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/24322226
Slow-sound photoacoustic microscopy. Zhang C, Zhou Y, Li C, Wang LV Applied physics letters 23696693 Appl Phys Lett 2013 Apr 22 https://www.ncbi.nlm.nih.gov/pubmed/23696693
Graphene-based contrast agents for photoacoustic and thermoacoustic tomography. Lalwani G, Cai X, Nie L, Wang LV, Sitharaman B Photoacoustics 24490141 Photoacoustics 2013 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/24490141
Small-animal whole-body photoacoustic tomography: a review. Xia J, Wang LV IEEE transactions on bio-medical engineering 24108456 IEEE Trans Biomed Eng 2014 May https://www.ncbi.nlm.nih.gov/pubmed/24108456
Multicontrast photoacoustic in vivo imaging using near-infrared fluorescent proteins. Krumholz A, Shcherbakova DM, Xia J, Wang LV, Verkhusha VV Scientific reports 24487319 Sci Rep 2014 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/24487319
Spatially Fourier-encoded photoacoustic microscopy using a digital micromirror device. Liang J, Gao L, Li C, Wang LV Optics letters 24487832 Opt Lett 2014 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/24487832
Ultrasonically encoded photoacoustic flowgraphy in biological tissue. Wang L, Xia J, Yao J, Maslov KI, Wang LV Physical review letters 24289689 Phys Rev Lett 2013 Nov 15 https://www.ncbi.nlm.nih.gov/pubmed/24289689
Photoacoustic recovery after photothermal bleaching in living cells. Li C, Zhang C, Gao L, Garcia-Uribe A, Wang LV Journal of biomedical optics 24089253 J Biomed Opt 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/24089253
Time-reversed ultrasonically encoded optical focusing using two ultrasonic transducers for improved ultrasonic axial resolution. Yang Q, Xu X, Lai P, Xu D, Wang LV Journal of biomedical optics 24194060 J Biomed Opt 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/24194060
Catheter-based photoacoustic endoscope. Yang JM, Li C, Chen R, Zhou Q, Shung KK, Wang LV Journal of biomedical optics 24887743 J Biomed Opt 2014 Jun https://www.ncbi.nlm.nih.gov/pubmed/24887743
Dependence of optical scattering from Intralipid in gelatin-gel based tissue-mimicking phantoms on mixing temperature and time. Lai P, Xu X, Wang LV Journal of biomedical optics 24604534 J Biomed Opt 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24604534
High-speed alignment optimization of digital optical phase conjugation systems based on autocovariance analysis in conjunction with orthonormal rectangular polynomials. Hemphill AS, Shen Y, Hwang J, Wang LV Journal of biomedical optics 30156064 J Biomed Opt 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/30156064
Angular-spectrum modeling of focusing light inside scattering media by optical phase conjugation. Yang J, Li J, He S, Wang LV Optica 32025534 Optica 2019 Mar 20 https://www.ncbi.nlm.nih.gov/pubmed/32025534
Label-free high-throughput photoacoustic tomography of suspected circulating melanoma tumor cells in patients in vivo. Hai P, Qu Y, Li Y, Zhu L, Shmuylovich L, Cornelius LA, Wang LV Journal of biomedical optics 32170857 J Biomed Opt 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/32170857
High-resolution, high-contrast mid-infrared imaging of fresh biological samples with ultraviolet-localized photoacoustic microscopy. Shi J, Wong TTW, He Y, Li L, Zhang R, Yung CS, Hwang J, Maslov K, Wang LV Nature photonics 31440304 Nat Photonics 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31440304
Synthetic Bessel light needle for extended depth-of-field microscopy. Yang J, Gong L, Shen Y, Wang LV Applied physics letters 30449893 Appl Phys Lett 2018 Oct 29 https://www.ncbi.nlm.nih.gov/pubmed/30449893
Dual-axis illumination for virtually augmenting the detection view of optical-resolution photoacoustic microscopy. Hsu HC, Li L, Yao J, Wong TTW, Shi J, Chen R, Zhou Q, Wang L Journal of biomedical optics 29981225 J Biomed Opt 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29981225
Single-exposure optical focusing inside scattering media using binarized time-reversed adapted perturbation. Ma C, Zhou F, Liu Y, Wang LV Optica 30221184 Optica 2015 Oct https://www.ncbi.nlm.nih.gov/pubmed/30221184
Structured-illumination photoacoustic Doppler flowmetry of axial flow in homogeneous scattering media. Zhang R, Yao J, Maslov KI, Wang LV Applied physics letters 24065864 Appl Phys Lett 2013 Aug 26 https://www.ncbi.nlm.nih.gov/pubmed/24065864
Enhancement of photoacoustic tomography by ultrasonic computed tomography based on optical excitation of elements of a full-ring transducer array. Xia J, Huang C, Maslov K, Anastasio MA, Wang LV Optics letters 24104670 Opt Lett 2013 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/24104670
Calibration-free quantification of absolute oxygen saturation based on the dynamics of photoacoustic signals. Xia J, Danielli A, Liu Y, Wang L, Maslov K, Wang LV Optics letters 23903146 Opt Lett 2013 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/23903146
Bessel-beam Grueneisen relaxation photoacoustic microscopy with extended depth of field. Shi J, Wang L, Noordam C, Wang LV Journal of biomedical optics 26524679 J Biomed Opt 2015 Nov https://www.ncbi.nlm.nih.gov/pubmed/26524679
Dichroism-sensitive photoacoustic computed tomography. Qu Y, Li L, Shen Y, Wei X, Wong TTW, Hu P, Yao J, Maslov K, Wang LV Optica 30820444 Optica 2018 Apr 20 https://www.ncbi.nlm.nih.gov/pubmed/30820444
Transvaginal fast-scanning optical-resolution photoacoustic endoscopy. Qu Y, Li C, Shi J, Chen R, Xu S, Rafsanjani H, Maslov K, Krigman H, Garvey L, Hu P, Zhao P, Meyers K, Diveley E, Pizzella S, Muench L, Punyamurthy N, Goldstein N, Onwumere O, Alisio M, Meyenburg K, Maynard J, Helm K, Slaughter J, Barber S, Burger T, Kramer C, Chubiz J, Anderson M, McCarthy R, England SK, Macones GA, Zhou Q, Shung KK, Zou J, Stout MJ, Tuuli M, Wang LV Journal of biomedical optics 30520276 J Biomed Opt 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30520276
High-throughput, label-free, single-cell photoacoustic microscopy of intratumoral metabolic heterogeneity. Hai P, Imai T, Xu S, Zhang R, Aft RL, Zou J, Wang LV Nature biomedical engineering 30936431 Nat Biomed Eng 2019 May https://www.ncbi.nlm.nih.gov/pubmed/30936431
In vivo photoacoustic microscopy of human cuticle microvasculature with single-cell resolution. Hsu HC, Wang L, Wang LV Journal of biomedical optics 27207113 J Biomed Opt 2016 May 1 https://www.ncbi.nlm.nih.gov/pubmed/27207113
Microvascular quantification based on contour-scanning photoacoustic microscopy. Yeh C, Soetikno B, Hu S, Maslov KI, Wang LV Journal of biomedical optics 25223708 J Biomed Opt 2014 Sep https://www.ncbi.nlm.nih.gov/pubmed/25223708
Multiscale Functional and Molecular Photoacoustic Tomography. Yao J, Xia J, Wang LV Ultrasonic imaging 25933617 Ultrason Imaging 2016 Jan https://www.ncbi.nlm.nih.gov/pubmed/25933617
High-speed label-free functional photoacoustic microscopy of mouse brain in action. Yao J, Wang L, Yang JM, Maslov KI, Wong TT, Li L, Huang CH, Zou J, Wang LV Nature methods 25822799 Nat Methods 2015 May https://www.ncbi.nlm.nih.gov/pubmed/25822799
In vivo photoacoustic flowmetry at depths of the diffusive regime based on saline injection. Zhou Y, Poudel J, Li G, Wang LV Journal of biomedical optics 26267364 J Biomed Opt 2015 Aug https://www.ncbi.nlm.nih.gov/pubmed/26267364
Fast label-free multilayered histology-like imaging of human breast cancer by photoacoustic microscopy. Wong TTW, Zhang R, Hai P, Zhang C, Pleitez MA, Aft RL, Novack DV, Wang LV Science advances 28560329 Sci Adv 2017 May https://www.ncbi.nlm.nih.gov/pubmed/28560329
Single-impulse Panoramic Photoacoustic Computed Tomography of Small-animal Whole-body Dynamics at High Spatiotemporal Resolution. Li L, Zhu L, Ma C, Lin L, Yao J, Wang L, Maslov K, Zhang R, Chen W, Shi J, Wang LV Nature biomedical engineering 29333331 Nat Biomed Eng 2017 https://www.ncbi.nlm.nih.gov/pubmed/29333331
High-speed single-shot optical focusing through dynamic scattering media with full-phase wavefront shaping. Hemphill AS, Shen Y, Liu Y, Wang LV Applied physics letters 29249832 Appl Phys Lett 2017 Nov 27 https://www.ncbi.nlm.nih.gov/pubmed/29249832
Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation. Liu Y, Ma C, Shen Y, Shi J, Wang LV Optica 28815194 Optica 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/28815194
Time-reversed adapted-perturbation (TRAP) optical focusing onto dynamic objects inside scattering media. Ma C, Xu X, Liu Y, Wang LV Nature photonics 25530797 Nat Photonics 2014 Dec https://www.ncbi.nlm.nih.gov/pubmed/25530797
Tripling the detection view of high-frequency linear-array-based photoacoustic computed tomography by using two planar acoustic reflectors. Li G, Xia J, Wang K, Maslov K, Anastasio MA, Wang LV Quantitative imaging in medicine and surgery 25694954 Quant Imaging Med Surg 2015 Feb https://www.ncbi.nlm.nih.gov/pubmed/25694954
Multi-view optical resolution photoacoustic microscopy. Zhu L, Li L, Gao L, Wang LV Optica 25558469 Optica 2014 https://www.ncbi.nlm.nih.gov/pubmed/25558469
Continuous scanning of a time-reversed ultrasonically encoded optical focus by reflection-mode digital phase conjugation. Suzuki Y, Tay JW, Yang Q, Wang LV Optics letters 24978506 Opt Lett 2014 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/24978506
Fully motorized optical-resolution photoacoustic microscopy. Li L, Yeh C, Hu S, Wang L, Soetikno BT, Chen R, Zhou Q, Shung KK, Maslov KI, Wang LV Optics letters 24686689 Opt Lett 2014 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/24686689
Calibration-free absolute quantification of particle concentration by statistical analyses of photoacoustic signals in vivo. Zhou Y, Yao J, Maslov KI, Wang LV Journal of biomedical optics 24589987 J Biomed Opt 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24589987
Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor. Yuan H, Wilson CM, Xia J, Doyle SL, Li S, Fales AM, Liu Y, Ozaki E, Mulfaul K, Hanna G, Palmer GM, Wang LV, Grant GA, Vo-Dinh T Nanoscale 24619405 Nanoscale 2014 Apr 21 https://www.ncbi.nlm.nih.gov/pubmed/24619405
Improving limited-view photoacoustic tomography with an acoustic reflector. Huang B, Xia J, Maslov K, Wang LV Journal of biomedical optics 24285421 J Biomed Opt 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/24285421
Photoacoustic Brain Imaging: from Microscopic to Macroscopic Scales. Yao J, Wang LV Neurophotonics 25401121 Neurophotonics 2014 May 28 https://www.ncbi.nlm.nih.gov/pubmed/25401121
Microcirculatory changes identified by photoacoustic microscopy in patients with complex regional pain syndrome type I after stellate ganglion blocks. Zhou Y, Yi X, Xing W, Hu S, Maslov KI, Wang LV Journal of biomedical optics 25144451 J Biomed Opt 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/25144451
Near-infrared optical-resolution photoacoustic microscopy. Hai P, Yao J, Maslov KI, Zhou Y, Wang LV Optics letters 25166107 Opt Lett 2014 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/25166107
Frequency-swept time-reversed ultrasonically encoded optical focusing. Suzuki Y, Wang LV Applied physics letters 25425744 Appl Phys Lett 2014 Nov 10 https://www.ncbi.nlm.nih.gov/pubmed/25425744
Label-free photoacoustic nanoscopy. Danielli A, Maslov K, Garcia-Uribe A, Winkler AM, Li C, Wang L, Chen Y, Dorn GW 2nd, Wang LV Journal of biomedical optics 25104412 J Biomed Opt 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/25104412
High-resolution photoacoustic tomography of resting-state functional connectivity in the mouse brain. Nasiriavanaki M, Xia J, Wan H, Bauer AQ, Culver JP, Wang LV Proceedings of the National Academy of Sciences of the United States of America 24367107 Proc Natl Acad Sci U S A 2014 Jan 7 https://www.ncbi.nlm.nih.gov/pubmed/24367107
Optical sectioning by wide-field photobleaching imprinting microscopy. Li C, Gao L, Liu Y, Wang LV Applied physics letters 24273331 Appl Phys Lett 2013 Oct 28 https://www.ncbi.nlm.nih.gov/pubmed/24273331
Absolute photoacoustic thermometry in deep tissue. Yao J, Ke H, Tai S, Zhou Y, Wang LV Optics letters 24322224 Opt Lett 2013 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/24322224
Urogenital photoacoustic endoscope. Li C, Yang JM, Chen R, Yeh CH, Zhu L, Maslov K, Zhou Q, Shung KK, Wang LV Optics letters 24690816 Opt Lett 2014 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/24690816
Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media. Yao J, Gilson RC, Maslov KI, Wang L, Wang LV Journal of biomedical optics 24718385 J Biomed Opt 2014 Apr https://www.ncbi.nlm.nih.gov/pubmed/24718385
Ultrasonic-heating-encoded photoacoustic tomography with virtually augmented detection view. Wang L, Li G, Xia J, Wang LV Optica 25984555 Optica 2015 https://www.ncbi.nlm.nih.gov/pubmed/25984555
Integrated photoacoustic, confocal, and two-photon microscope. Rao B, Soto F, Kerschensteiner D, Wang LV Journal of biomedical optics 24589986 J Biomed Opt 2014 Mar https://www.ncbi.nlm.nih.gov/pubmed/24589986
Cross-correlation-based transverse flow measurements using optical resolution photoacoustic microscopy with a digital micromirror device. Liang J, Zhou Y, Maslov KI, Wang LV Journal of biomedical optics 24002191 J Biomed Opt 2013 Sep https://www.ncbi.nlm.nih.gov/pubmed/24002191
Nonlinear light-sheet fluorescence microscopy by photobleaching imprinting. Gao L, Zhu L, Li C, Wang LV Journal of the Royal Society, Interface 24478278 J R Soc Interface 2014 Apr 6 https://www.ncbi.nlm.nih.gov/pubmed/24478278
A microrobotic system guided by photoacoustic computed tomography for targeted navigation in intestines in vivo. Wu Z, Li L, Yang Y, Hu P, Li Y, Yang SY, Wang LV, Gao W Science robotics 32632399 Sci Robot 2019 Jul 31 https://www.ncbi.nlm.nih.gov/pubmed/32632399
Ultrasonically encoded wavefront shaping for focusing into random media. Tay JW, Lai P, Suzuki Y, Wang LV Scientific reports 24472822 Sci Rep 2014 Jan 29 https://www.ncbi.nlm.nih.gov/pubmed/24472822
Label-free photoacoustic microscopy of peripheral nerves. Matthews TP, Zhang C, Yao DK, Maslov K, Wang LV Journal of biomedical optics 24395587 J Biomed Opt 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/24395587
Photoacoustic measurement of the Grüneisen parameter of tissue. Yao DK, Zhang C, Maslov K, Wang LV Journal of biomedical optics 24474512 J Biomed Opt 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/24474512
Photobleaching imprinting microscopy: seeing clearer and deeper. Gao L, Garcia-Uribe A, Liu Y, Li C, Wang LV Journal of cell science 24317295 J Cell Sci 2014 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/24317295
Three-dimensional arbitrary trajectory scanning photoacoustic microscopy. Yeh C, Soetikno B, Hu S, Maslov KI, Wang LV Journal of biophotonics 25077689 J Biophotonics 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25077689
Reversibly switchable fluorescence microscopy with enhanced resolution and image contrast. Yao J, Shcherbakova DM, Li C, Krumholz A, Lorca RA, Reinl E, England SK, Verkhusha VV, Wang LV Journal of biomedical optics 25144452 J Biomed Opt 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/25144452
Retrospective respiration-gated whole-body photoacoustic computed tomography of mice. Xia J, Chen W, Maslov K, Anastasio MA, Wang LV Journal of biomedical optics 24395586 J Biomed Opt 2014 Jan https://www.ncbi.nlm.nih.gov/pubmed/24395586
Photoimprint photoacoustic microscopy for three-dimensional label-free subdiffraction imaging. Yao J, Wang L, Li C, Zhang C, Wang LV Physical review letters 24483902 Phys Rev Lett 2014 Jan 10 https://www.ncbi.nlm.nih.gov/pubmed/24483902
Photoacoustic and optical coherence tomography of epilepsy with high temporal and spatial resolution and dual optical contrasts. Tsytsarev V, Rao B, Maslov KI, Li L, Wang LV Journal of neuroscience methods 23603664 J Neurosci Methods 2013 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/23603664
Reflection-mode multifocal optical-resolution photoacoustic microscopy. Li G, Maslov KI, Wang LV Journal of biomedical optics 23446704 J Biomed Opt 2013 Mar https://www.ncbi.nlm.nih.gov/pubmed/23446704
Ultrasound-heated photoacoustic flowmetry. Wang L, Yao J, Maslov KI, Xing W, Wang LV Journal of biomedical optics 24194064 J Biomed Opt 2013 Nov https://www.ncbi.nlm.nih.gov/pubmed/24194064
Deep-tissue photoacoustic tomography of Förster resonance energy transfer. Wang Y, Xia J, Wang LV Journal of biomedical optics 23884608 J Biomed Opt 2013 Oct https://www.ncbi.nlm.nih.gov/pubmed/23884608
Amplitude-masked photoacoustic wavefront shaping and application in flowmetry. Tay JW, Liang J, Wang LV Optics letters 25360912 Opt Lett 2014 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/25360912
Grueneisen relaxation photoacoustic microscopy. Wang L, Zhang C, Wang LV Physical review letters 25379919 Phys Rev Lett 2014 Oct 24 https://www.ncbi.nlm.nih.gov/pubmed/25379919
In vivo deep brain imaging of rats using oral-cavity illuminated photoacoustic computed tomography. Lin L, Xia J, Wong TT, Li L, Wang LV Journal of biomedical optics 25611865 J Biomed Opt 2015 Jan https://www.ncbi.nlm.nih.gov/pubmed/25611865
Photoacoustic tomography: principles and advances. Xia J, Yao J, Wang LV Electromagnetic waves (Cambridge, Mass.) 25642127 Electromagn Waves (Camb) 2014 https://www.ncbi.nlm.nih.gov/pubmed/25642127
Optical drug monitoring: photoacoustic imaging of nanosensors to monitor therapeutic lithium in vivo. Cash KJ, Li C, Xia J, Wang LV, Clark HA ACS nano 25588028 ACS Nano 2015 Feb 24 https://www.ncbi.nlm.nih.gov/pubmed/25588028
Single-shot compressed ultrafast photography at one hundred billion frames per second. Gao L, Liang J, Li C, Wang LV Nature 25471883 Nature 2014 Dec 4 https://www.ncbi.nlm.nih.gov/pubmed/25471883
alphaVbeta3-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment. Zhang R, Pan D, Cai X, Yang X, Senpan A, Allen JS, Lanza GM, Wang LV Theranostics 25553103 Theranostics 2015 https://www.ncbi.nlm.nih.gov/pubmed/25553103
Noninvasive photoacoustic microscopy of methemoglobin in vivo. Tang M, Zhou Y, Zhang R, Wang LV Journal of biomedical optics 25760655 J Biomed Opt 2015 Mar https://www.ncbi.nlm.nih.gov/pubmed/25760655
Nonlinear photoacoustic spectroscopy of hemoglobin. Danielli A, Maslov K, Favazza CP, Xia J, Wang LV Applied physics letters 26045627 Appl Phys Lett 2015 May 18 https://www.ncbi.nlm.nih.gov/pubmed/26045627
Multiview Hilbert transformation for full-view photoacoustic computed tomography using a linear array. Li G, Li L, Zhu L, Xia J, Wang LV Journal of biomedical optics 26112369 J Biomed Opt 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/26112369
Photoacoustic microscopy of arteriovenous shunts and blood diffusion in early-stage tumors. Yeh C, Liang J, Zhou Y, Hu S, Sohn RE, Arbeit JM, Wang LV Journal of biomedical optics 26882446 J Biomed Opt 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/26882446
Photoacoustic microscopy: superdepth, superresolution, and superb contrast. Yao J, Song L, Wang LV IEEE pulse 25974913 IEEE Pulse 2015 May-Jun https://www.ncbi.nlm.nih.gov/pubmed/25974913
In vivo photoacoustic tomography of myoglobin oxygen saturation. Lin L, Yao J, Li L, Wang LV Journal of biomedical optics 26719943 J Biomed Opt 2016 Jun https://www.ncbi.nlm.nih.gov/pubmed/26719943
Hybridized wavefront shaping for high-speed, high-efficiency focusing through dynamic diffusive media. Hemphill AS, Tay JW, Wang LV Journal of biomedical optics 27626770 J Biomed Opt 2016 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/27626770
A practical guide to photoacoustic tomography in the life sciences. Wang LV, Yao J Nature methods 27467726 Nat Methods 2016 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/27467726
In vivo label-free photoacoustic flow cytography and on-the-spot laser killing of single circulating melanoma cells. He Y, Wang L, Shi J, Yao J, Li L, Zhang R, Huang CH, Zou J, Wang LV Scientific reports 28000788 Sci Rep 2016 Dec 21 https://www.ncbi.nlm.nih.gov/pubmed/28000788
Grueneisen relaxation photoacoustic microscopy in vivo. Ma J, Shi J, Hai P, Zhou Y, Wang LV Journal of biomedical optics 27272096 J Biomed Opt 2016 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/27272096
Quantitative photoacoustic elastography in humans. Hai P, Zhou Y, Gong L, Wang LV Journal of biomedical optics 27304419 J Biomed Opt 2016 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/27304419
Dry coupling for whole-body small-animal photoacoustic computed tomography. Yeh C, Li L, Zhu L, Xia J, Li C, Chen W, Garcia-Uribe A, Maslov KI, Wang LV Journal of biomedical optics 28241305 J Biomed Opt 2017 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/28241305
Use of a single xenon flash lamp for photoacoustic computed tomography of multiple-centimeter-thick biological tissue ex vivo and a whole mouse body in vivo. Wong TT, Zhou Y, Garcia-Uribe A, Li L, Maslov K, Lin L, Wang LV Journal of biomedical optics 27775747 J Biomed Opt 2017 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/27775747
Multiview Hilbert transformation in full-ring transducer array-based photoacoustic computed tomography. Li L, Zhu L, Shen Y, Wang LV Journal of biomedical optics 28745385 J Biomed Opt 2017 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/28745385
Integration of Multitargeted Polymer-Based Contrast Agents with Photoacoustic Computed Tomography: An Imaging Technique to Visualize Breast Cancer Intratumor Heterogeneity. Li L, Patil D, Petruncio G, Harnden KK, Somasekharan JV, Paige M, Wang LV, Salvador-Morales C ACS nano 33464827 ACS Nano 2021 Feb 23 https://www.ncbi.nlm.nih.gov/pubmed/33464827
Photoacoustic computed tomography of human extremities. Wray P, Lin L, Hu P, Wang LV Journal of biomedical optics 30784244 J Biomed Opt 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30784244
The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle. Díaz-García CM, Meyer DJ, Nathwani N, Rahman M, Martínez-François JR, Yellen G eLife 33555254 Elife 2021 Feb 8 https://www.ncbi.nlm.nih.gov/pubmed/33555254
Snapshot Photoacoustic Topography Through an Ergodic Relay for High-throughput Imaging of Optical Absorption. Li Y, Li L, Zhu L, Maslov K, Shi J, Hu P, Bo E, Yao J, Liang J, Wang L, Wang LV Nature photonics 34178097 Nat Photonics 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/34178097
Real-time observation and control of optical chaos. Fan L, Yan X, Wang H, Wang LV Science advances 33523874 Sci Adv 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33523874
Dual-view photoacoustic microscopy for quantitative cell nuclear imaging. Cai D, Wong TTW, Zhu L, Shi J, Chen SL, Wang LV Optics letters 30320772 Opt Lett 2018 Oct 15 https://www.ncbi.nlm.nih.gov/pubmed/30320772
Micromachined Silicon Parallel Acoustic Delay Lines as Time Delayed Ultrasound Detector Array for Real-Time Photoacoustic Tomography. Cho Y, Chang CC, Wang LV, Zou J Journal of optics (2010) 31998470 J Opt 2016 https://www.ncbi.nlm.nih.gov/pubmed/31998470
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Motionless volumetric photoacoustic microscopy with spatially invariant resolution. Yang J, Gong L, Xu X, Hai P, Shen Y, Suzuki Y, Wang LV Nature communications 28974681 Nat Commun 2017 Oct 3 https://www.ncbi.nlm.nih.gov/pubmed/28974681
In vivo characterization of connective tissue remodeling using infrared photoacoustic spectra. Qu Y, Hu P, Shi J, Maslov K, Zhao P, Li C, Ma J, Garcia-Uribe A, Meyers K, Diveley E, Pizzella S, Muench L, Punyamurthy N, Goldstein N, Onwumere O, Alisio M, Meyenburg K, Maynard J, Helm K, Altieri E, Slaughter J, Barber S, Burger T, Kramer C, Chubiz J, Anderson M, McCarthy R, England SK, Macones GA, Stout MJ, Tuuli M, Wang LV Journal of biomedical optics 30520275 J Biomed Opt 2018 Dec https://www.ncbi.nlm.nih.gov/pubmed/30520275
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Peak Annotation and Verification Engine for Untargeted LC-MS Metabolomics. Wang L, Xing X, Chen L, Yang L, Su X, Rabitz H, Lu W, Rabinowitz JD Analytical chemistry 30586294 Anal Chem 2019 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/30586294
The small intestine shields the liver from fructose-induced steatosis. Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz JD Nature metabolism 32694791 Nat Metab 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32694791
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt EC, Piqueras-Nebot M, Gomez-Cabrera MC, Lahoz A, Fan J, Beier UH, Kim H, Rabinowitz JD Nature chemical biology 32393898 Nat Chem Biol 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32393898
Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8(+) T cell stemness and antitumor immunity. Hermans D, Gautam S, García-Cañaveras JC, Gromer D, Mitra S, Spolski R, Li P, Christensen S, Nguyen R, Lin JX, Oh J, Du N, Veenbergen S, Fioravanti J, Ebina-Shibuya R, Bleck C, Neckers LM, Rabinowitz JD, Gattinoni L, Leonard WJ Proceedings of the National Academy of Sciences of the United States of America 32123114 Proc Natl Acad Sci U S A 2020 Mar 17 https://www.ncbi.nlm.nih.gov/pubmed/32123114
Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Dekhne AS, Shah K, Ducker GS, Katinas JM, Wong-Roushar J, Nayeen MJ, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O'Connor C, Dzinic SH, White K, Kushner J, Kim S, Hüttemann M, Polin L, Rabinowitz JD, Li J, Hou Z, Dann CE 3rd, Gangjee A, Matherly LH Molecular cancer therapeutics 31289137 Mol Cancer Ther 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31289137
Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z Cell metabolism 30449684 Cell Metab 2019 Feb 5 https://www.ncbi.nlm.nih.gov/pubmed/30449684
Metabolite Exchange between Mammalian Organs Quantified in Pigs. Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido GA 2nd, Gorman JH 3rd, Gorman RC, Rabinowitz JD Cell metabolism 36070684 Cell Metab 2022 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/36070684
Four Key Steps Control Glycolytic Flux in Mammalian Cells. Tanner LB, Goglia AG, Wei MH, Sehgal T, Parsons LR, Park JO, White E, Toettcher JE, Rabinowitz JD Cell systems 29960885 Cell Syst 2018 Jul 25 https://www.ncbi.nlm.nih.gov/pubmed/29960885
Slow TCA flux and ATP production in primary solid tumours but not metastases. Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Vander Heiden MG, Herranz D, Guo JY, Kang Y, Rabinowitz JD Nature 36725930 Nature 2023 Feb https://www.ncbi.nlm.nih.gov/pubmed/36725930
One-carbon unit supplementation fuels tumor-infiltrating T cells and augments checkpoint blockade. Xu X, Chen Z, Bartman CR, Xing X, Olszewski K, Rabinowitz JD bioRxiv : the preprint server for biology 37961420 bioRxiv 2023 Nov 3 https://www.ncbi.nlm.nih.gov/pubmed/37961420
Reprogramming neuroblastoma by diet-enhanced polyamine depletion. Cherkaoui S, Yang L, McBride M, Turn CS, Lu W, Eigenmann C, Allen GE, Panasenko OO, Zhang L, Vu A, Liu K, Li Y, Gandhi OH, Surrey L, Wierer M, White E, Rabinowitz JD, Hogarty MD, Morscher RJ bioRxiv : the preprint server for biology 38260457 bioRxiv 2024 Jan 8 https://www.ncbi.nlm.nih.gov/pubmed/38260457
Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors. Roichman A, Zuo Q, Hwang S, Lu W, Cordova RA, MacArthur MR, Boyer JA, Mitchell SJ, Powers J, Koval SA, Hunter CJ, Rijmers J, Ryseck RP, AbuSalim JE, Chatterjee S, Lee WD, Xu X, Xing X, Chen Z, Zeng X, Marwaha S, McBride MJ, Guo JY, Kang Y, Donia MS, Rabinowitz JD Cell 40393457 Cell 2025 May 29 https://www.ncbi.nlm.nih.gov/pubmed/40393457
Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, Joshi AU, He JQ, Gauba E, Liu L, Wang C, Linde M, Sugiura Y, Moon PK, Majeti R, Suematsu M, Mochly-Rosen D, Weissman IL, Longo FM, Rabinowitz JD, Andreasson KI Nature 33473210 Nature 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33473210
5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. Rodan LH, Qi W, Ducker GS, Demirbas D, Laine R, Yang E, Walker MA, Eichler F, Rabinowitz JD, Anselm I, Berry GT, Undiagnosed Diseases Network (UDN) Molecular genetics and metabolism 30031689 Mol Genet Metab 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30031689
Lactate: the ugly duckling of energy metabolism. Rabinowitz JD, Enerbäck S Nature metabolism 32694798 Nat Metab 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32694798
Quantitative Fluxomics of Circulating Metabolites. Hui S, Cowan AJ, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz JD Cell metabolism 32791100 Cell Metab 2020 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/32791100
Improved Annotation of Untargeted Metabolomics Data through Buffer Modifications That Shift Adduct Mass and Intensity. Lu W, Xing X, Wang L, Chen L, Zhang S, McReynolds MR, Rabinowitz JD Analytical chemistry 32614575 Anal Chem 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/32614575
Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis. Ghergurovich JM, Esposito M, Chen Z, Wang JZ, Bhatt V, Lan T, White E, Kang Y, Guo JY, Rabinowitz JD Cancer research 32661137 Cancer Res 2020 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/32661137
Glucose feeds the TCA cycle via circulating lactate. Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Le Zhan, Yanxiang Guo J, White E, Rabinowitz JD Nature 29045397 Nature 2017 Nov 2 https://www.ncbi.nlm.nih.gov/pubmed/29045397
Metabolomics and Isotope Tracing. Jang C, Chen L, Rabinowitz JD Cell 29727671 Cell 2018 May 3 https://www.ncbi.nlm.nih.gov/pubmed/29727671
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. Liu L, Su X, Quinn WJ 3rd, Hui S, Krukenberg K, Frederick DW, Redpath P, Zhan L, Chellappa K, White E, Migaud M, Mitchison TJ, Baur JA, Rabinowitz JD Cell metabolism 29685734 Cell Metab 2018 May 1 https://www.ncbi.nlm.nih.gov/pubmed/29685734
GCN2 adapts protein synthesis to scavenging-dependent growth. Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z, Anthony TG, Wühr M, Sabatini DM, Rabinowitz JD Cell systems 34706266 Cell Syst 2022 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/34706266
Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction. Green CL, Pak HH, Richardson NE, Flores V, Yu D, Tomasiewicz JL, Dumas SN, Kredell K, Fan JW, Kirsh C, Chaiyakul K, Murphy ME, Babygirija R, Barrett-Wilt GA, Rabinowitz J, Ong IM, Jang C, Simcox J, Lamming DW Cell metabolism 35108511 Cell Metab 2022 Feb 1 https://www.ncbi.nlm.nih.gov/pubmed/35108511
Spatially resolved isotope tracing reveals tissue metabolic activity. Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM Nature methods 35132243 Nat Methods 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/35132243
Impact of acute stress on murine metabolomics and metabolic flux. Lee WD, Liang L, AbuSalim J, Jankowski CSR, Samarah LZ, Neinast MD, Rabinowitz JD Proceedings of the National Academy of Sciences of the United States of America 37186827 Proc Natl Acad Sci U S A 2023 May 23 https://www.ncbi.nlm.nih.gov/pubmed/37186827
NAD precursors cycle between host tissues and the gut microbiome. Chellappa K, McReynolds MR, Lu W, Zeng X, Makarov M, Hayat F, Mukherjee S, Bhat YR, Lingala SR, Shima RT, Descamps HC, Cox T, Ji L, Jankowski C, Chu Q, Davidson SM, Thaiss CA, Migaud ME, Rabinowitz JD, Baur JA Cell metabolism 36476934 Cell Metab 2022 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/36476934
Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors. Lu W, Wang L, Chen L, Hui S, Rabinowitz JD Antioxidants & redox signaling 28497978 Antioxid Redox Signal 2018 Jan 20 https://www.ncbi.nlm.nih.gov/pubmed/28497978
The metabolites NADP(+) and NADPH are the targets of the circadian protein Nocturnin (Curled). Estrella MA, Du J, Chen L, Rath S, Prangley E, Chitrakar A, Aoki T, Schedl P, Rabinowitz J, Korennykh A Nature communications 31147539 Nat Commun 2019 May 30 https://www.ncbi.nlm.nih.gov/pubmed/31147539
Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain. McKee SE, Zhang S, Chen L, Rabinowitz JD, Reyes TM Journal of neurochemistry 29423909 J Neurochem 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29423909
Glycine homeostasis requires reverse SHMT flux. McBride MJ, Hunter CJ, Zhang Z, TeSlaa T, Xu X, Ducker GS, Rabinowitz JD Cell metabolism 38171330 Cell Metab 2024 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/38171330
Many circulating indole and phenol metabolites are host derived. AbuSalim JE, Olszewski K, Youssef S, Hunter CJ, MacArthur MR, Henneberg A, Ryseck RP, Opitz CA, Donia MS, Rabinowitz JD bioRxiv : the preprint server for biology 41279320 bioRxiv 2025 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/41279320
CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs. Wu J, Vilarino M, Suzuki K, Okamura D, Bogliotti YS, Park I, Rowe J, McNabb B, Ross PJ, Belmonte JCI Scientific reports 28874671 Sci Rep 2017 Sep 5 https://www.ncbi.nlm.nih.gov/pubmed/28874671
Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures. Li R, Zhong C, Yu Y, Liu H, Sakurai M, Yu L, Min Z, Shi L, Wei Y, Takahashi Y, Liao HK, Qiao J, Deng H, Nuñez-Delicado E, Rodriguez Esteban C, Wu J, Izpisua Belmonte JC Cell 31626770 Cell 2019 Oct 17 https://www.ncbi.nlm.nih.gov/pubmed/31626770
Functional sensory circuits built from neurons of two species. Throesch BT, Bin Imtiaz MK, Muñoz-Castañeda R, Sakurai M, Hartzell AL, James KN, Rodriguez AR, Martin G, Lippi G, Kupriyanov S, Wu Z, Osten P, Izpisua Belmonte JC, Wu J, Baldwin KK Cell 38670072 Cell 2024 Apr 25 https://www.ncbi.nlm.nih.gov/pubmed/38670072
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction. Suzuki K, Yamamoto M, Hernandez-Benitez R, Li Z, Wei C, Soligalla RD, Aizawa E, Hatanaka F, Kurita M, Reddy P, Ocampo A, Hishida T, Sakurai M, Nemeth AN, Nuñez Delicado E, Campistol JM, Magistretti P, Guillen P, Rodriguez Esteban C, Gong J, Yuan Y, Gu Y, Liu GH, López-Otín C, Wu J, Zhang K, Izpisua Belmonte JC Cell research 31444470 Cell Res 2019 Oct https://www.ncbi.nlm.nih.gov/pubmed/31444470
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Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts. Bogliotti YS, Wu J, Vilarino M, Okamura D, Soto DA, Zhong C, Sakurai M, Sampaio RV, Suzuki K, Izpisua Belmonte JC, Ross PJ Proceedings of the National Academy of Sciences of the United States of America 29440377 Proc Natl Acad Sci U S A 2018 Feb 27 https://www.ncbi.nlm.nih.gov/pubmed/29440377
Deconstructing the pluripotency gene regulatory network. Li M, Izpisua Belmonte JC Nature cell biology 29593328 Nat Cell Biol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29593328
Microbiome: Focus on Causation and Mechanism. Fischbach MA Cell 30096310 Cell 2018 Aug 9 https://www.ncbi.nlm.nih.gov/pubmed/30096310
A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites. Dodd D, Spitzer MH, Van Treuren W, Merrill BD, Hryckowian AJ, Higginbottom SK, Le A, Cowan TM, Nolan GP, Fischbach MA, Sonnenburg JL Nature 29168502 Nature 2017 Nov 30 https://www.ncbi.nlm.nih.gov/pubmed/29168502
MAIT cells are imprinted by the microbiota in early life and promote tissue repair. Constantinides MG, Link VM, Tamoutounour S, Wong AC, Perez-Chaparro PJ, Han SJ, Chen YE, Li K, Farhat S, Weckel A, Krishnamurthy SR, Vujkovic-Cvijin I, Linehan JL, Bouladoux N, Merrill ED, Roy S, Cua DJ, Adams EJ, Bhandoola A, Scharschmidt TC, Aubé J, Fischbach MA, Belkaid Y Science (New York, N.Y.) 31649166 Science 2019 Oct 25 https://www.ncbi.nlm.nih.gov/pubmed/31649166
A metabolic pathway for bile acid dehydroxylation by the gut microbiome. Funabashi M, Grove TL, Wang M, Varma Y, McFadden ME, Brown LC, Guo C, Higginbottom S, Almo SC, Fischbach MA Nature 32555455 Nature 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32555455
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota. Lima-Junior DS, Krishnamurthy SR, Bouladoux N, Collins N, Han SJ, Chen EY, Constantinides MG, Link VM, Lim AI, Enamorado M, Cataisson C, Gil L, Rao I, Farley TK, Koroleva G, Attig J, Yuspa SH, Fischbach MA, Kassiotis G, Belkaid Y Cell 34166614 Cell 2021 Jul 8 https://www.ncbi.nlm.nih.gov/pubmed/34166614
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential. Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, Tang WHW, Lusis AJ, Rey FE, Fischbach MA, Hazen SL Circulation research 30359185 Circ Res 2018 Oct 26 https://www.ncbi.nlm.nih.gov/pubmed/30359185
The gutSMASH web server: automated identification of primary metabolic gene clusters from the gut microbiota. Pascal Andreu V, Roel-Touris J, Dodd D, Fischbach MA, Medema MH Nucleic acids research 34019648 Nucleic Acids Res 2021 Jul 2 https://www.ncbi.nlm.nih.gov/pubmed/34019648
CRISPR-based functional genomics in human dendritic cells. Jost M, Jacobson AN, Hussmann JA, Cirolia G, Fischbach MA, Weissman JS eLife 33904395 Elife 2021 Apr 27 https://www.ncbi.nlm.nih.gov/pubmed/33904395
A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles. Claesen J, Spagnolo JB, Ramos SF, Kurita KL, Byrd AL, Aksenov AA, Melnik AV, Wong WR, Wang S, Hernandez RD, Donia MS, Dorrestein PC, Kong HH, Segre JA, Linington RG, Fischbach MA, Lemon KP Science translational medicine 33208503 Sci Transl Med 2020 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/33208503
Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression. Nimer N, Choucair I, Wang Z, Nemet I, Li L, Gukasyan J, Weeks TL, Alkhouri N, Zein N, Tang WHW, Fischbach MA, Brown JM, Allayee H, Dasarathy S, Gogonea V, Hazen SL Metabolism: clinical and experimental 33275980 Metabolism 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33275980
The Biosynthesis of Lipooligosaccharide from Bacteroides thetaiotaomicron. Jacobson AN, Choudhury BP, Fischbach MA mBio 29535205 mBio 2018 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/29535205
Depletion of microbiome-derived molecules in the host using Clostridium genetics. Guo CJ, Allen BM, Hiam KJ, Dodd D, Van Treuren W, Higginbottom S, Nagashima K, Fischer CR, Sonnenburg JL, Spitzer MH, Fischbach MA Science (New York, N.Y.) 31831639 Science 2019 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/31831639
Mapping the Genetic Landscape of Human Cells. Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA Cell 30033366 Cell 2018 Aug 9 https://www.ncbi.nlm.nih.gov/pubmed/30033366
Design, construction, and in vivo augmentation of a complex gut microbiome. Cheng AG, Ho PY, Aranda-Díaz A, Jain S, Yu FB, Meng X, Wang M, Iakiviak M, Nagashima K, Zhao A, Murugkar P, Patil A, Atabakhsh K, Weakley A, Yan J, Brumbaugh AR, Higginbottom S, Dimas A, Shiver AL, Deutschbauer A, Neff N, Sonnenburg JL, Huang KC, Fischbach MA Cell 36070752 Cell 2022 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/36070752
Comprehensive Clinical and Genetic Analyses of Circulating Bile Acids and Their Associations With Diabetes and Its Indices. Choucair I, Mallela DP, Hilser JR, Hartiala JA, Nemet I, Gogonea V, Li L, Lusis AJ, Fischbach MA, Tang WHW, Allayee H, Hazen SL Diabetes 38701355 Diabetes 2024 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/38701355
A metabolomics pipeline for the mechanistic interrogation of the gut microbiome. Han S, Van Treuren W, Fischer CR, Merrill BD, DeFelice BC, Sanchez JM, Higginbottom SK, Guthrie L, Fall LA, Dodd D, Fischbach MA, Sonnenburg JL Nature 34262212 Nature 2021 Jul https://www.ncbi.nlm.nih.gov/pubmed/34262212
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Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome. Wang M, Osborn LJ, Jain S, Meng X, Weakley A, Yan J, Massey WJ, Varadharajan V, Horak A, Banerjee R, Allende DS, Chan ER, Hajjar AM, Wang Z, Dimas A, Zhao A, Nagashima K, Cheng AG, Higginbottom S, Hazen SL, Brown JM, Fischbach MA Cell 37352836 Cell 2023 Jun 22 https://www.ncbi.nlm.nih.gov/pubmed/37352836
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Contextual control of skin immunity and inflammation by Corynebacterium. Ridaura VK, Bouladoux N, Claesen J, Chen YE, Byrd AL, Constantinides MG, Merrill ED, Tamoutounour S, Fischbach MA, Belkaid Y The Journal of experimental medicine 29382696 J Exp Med 2018 Mar 5 https://www.ncbi.nlm.nih.gov/pubmed/29382696
The Lymphatic System: Integral Roles in Immunity. Randolph GJ, Ivanov S, Zinselmeyer BH, Scallan JP Annual review of immunology 27860528 Annu Rev Immunol 2017 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/27860528
The Lymphatic Vasculature in the 21(st) Century: Novel Functional Roles in Homeostasis and Disease. Oliver G, Kipnis J, Randolph GJ, Harvey NL Cell 32707093 Cell 2020 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/32707093
Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure. Zou W, Rohatgi N, Brestoff JR, Moley JR, Li Y, Williams JW, Alippe Y, Pan H, Pietka TA, Mbalaviele G, Newberry EP, Davidson NO, Dey A, Shoghi KI, Head RD, Wickline SA, Randolph GJ, Abumrad NA, Teitelbaum SL The Journal of clinical investigation 32310225 J Clin Invest 2020 May 1 https://www.ncbi.nlm.nih.gov/pubmed/32310225
A Polecat's View of Patrolling Monocytes. Williams JW, Randolph GJ, Zinselmeyer BH Circulation research 28546349 Circ Res 2017 May 26 https://www.ncbi.nlm.nih.gov/pubmed/28546349
LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth. Zhang N, Kim SH, Gainullina A, Erlich EC, Onufer EJ, Kim J, Czepielewski RS, Helmink BA, Dominguez JR, Saunders BT, Ding J, Williams JW, Jiang JX, Segal BH, Zinselmeyer BH, Randolph GJ, Kim KW The Journal of experimental medicine 34714329 J Exp Med 2021 Dec 6 https://www.ncbi.nlm.nih.gov/pubmed/34714329
MHC II+ resident peritoneal and pleural macrophages rely on IRF4 for development from circulating monocytes. Kim KW, Williams JW, Wang YT, Ivanov S, Gilfillan S, Colonna M, Virgin HW, Gautier EL, Randolph GJ The Journal of experimental medicine 27551152 J Exp Med 2016 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/27551152
Liver injury after small bowel resection is prevented in obesity-resistant 129S1/SvImJ mice. Onufer EJ, Han YH, Courtney C, Steinberger A, Tecos M, Sutton S, Sescleifer A, Ou J, Sanguinetti Czepielewski R, Randolph GJ, Warner BW American journal of physiology. Gastrointestinal and liver physiology 33729834 Am J Physiol Gastrointest Liver Physiol 2021 May 1 https://www.ncbi.nlm.nih.gov/pubmed/33729834
Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression. Williams JW, Zaitsev K, Kim KW, Ivanov S, Saunders BT, Schrank PR, Kim K, Elvington A, Kim SH, Tucker CG, Wohltmann M, Fife BT, Epelman S, Artyomov MN, Lavine KJ, Zinselmeyer BH, Choi JH, Randolph GJ Nature immunology 32895539 Nat Immunol 2020 Oct https://www.ncbi.nlm.nih.gov/pubmed/32895539
Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models. Kim K, Shim D, Lee JS, Zaitsev K, Williams JW, Kim KW, Jang MY, Seok Jang H, Yun TJ, Lee SH, Yoon WK, Prat A, Seidah NG, Choi J, Lee SP, Yoon SH, Nam JW, Seong JK, Oh GT, Randolph GJ, Artyomov MN, Cheong C, Choi JH Circulation research 30359200 Circ Res 2018 Oct 26 https://www.ncbi.nlm.nih.gov/pubmed/30359200
Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells. Wu X, Briseño CG, Durai V, Albring JC, Haldar M, Bagadia P, Kim KW, Randolph GJ, Murphy TL, Murphy KM The Journal of experimental medicine 27810926 J Exp Med 2016 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/27810926
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression. Zhu Y, Herndon JM, Sojka DK, Kim KW, Knolhoff BL, Zuo C, Cullinan DR, Luo J, Bearden AR, Lavine KJ, Yokoyama WM, Hawkins WG, Fields RC, Randolph GJ, DeNardo DG Immunity 28813661 Immunity 2017 Aug 15 https://www.ncbi.nlm.nih.gov/pubmed/28813661
Lymphatic network remodeling after small bowel resection. Onufer EJ, Czepielewski R, Seiler KM, Erlich E, Courtney CM, Bustos A, Randolph GJ, Warner BW Journal of pediatric surgery 30879758 J Pediatr Surg 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/30879758
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity. Westerterp M, Gautier EL, Ganda A, Molusky MM, Wang W, Fotakis P, Wang N, Randolph GJ, D'Agati VD, Yvan-Charvet L, Tall AR Cell metabolism 28479366 Cell Metab 2017 Jun 6 https://www.ncbi.nlm.nih.gov/pubmed/28479366
Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity. Fonseca DM, Hand TW, Han SJ, Gerner MY, Glatman Zaretsky A, Byrd AL, Harrison OJ, Ortiz AM, Quinones M, Trinchieri G, Brenchley JM, Brodsky IE, Germain RN, Randolph GJ, Belkaid Y Cell 26451485 Cell 2015 Oct 8 https://www.ncbi.nlm.nih.gov/pubmed/26451485
CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability. Ivanov S, Scallan JP, Kim KW, Werth K, Johnson MW, Saunders BT, Wang PL, Kuan EL, Straub AC, Ouhachi M, Weinstein EG, Williams JW, Briseño C, Colonna M, Isakson BE, Gautier EL, Förster R, Davis MJ, Zinselmeyer BH, Randolph GJ The Journal of clinical investigation 26999610 J Clin Invest 2016 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/26999610
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Enterically derived high-density lipoprotein restrains liver injury through the portal vein. Han YH, Onufer EJ, Huang LH, Sprung RW, Davidson WS, Czepielewski RS, Wohltmann M, Sorci-Thomas MG, Warner BW, Randolph GJ Science (New York, N.Y.) 34437091 Science 2021 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/34437091
A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages. Buechler MB, Kim KW, Onufer EJ, Williams JW, Little CC, Dominguez CX, Li Q, Sandoval W, Cooper JE, Harris CA, Junttila MR, Randolph GJ, Turley SJ Immunity 31231034 Immunity 2019 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/31231034
Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood. Williams JW, Elvington A, Ivanov S, Kessler S, Luehmann H, Baba O, Saunders BT, Kim KW, Johnson MW, Craft CS, Choi JH, Sorci-Thomas MG, Zinselmeyer BH, Brestoff JR, Liu Y, Randolph GJ Circulation research 28696252 Circ Res 2017 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/28696252
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Effects of nicotine on DARPP-32 and CaMKII signaling relevant to addiction. Lee AM, Picciotto MR Advances in pharmacology (San Diego, Calif.) 33706940 Adv Pharmacol 2021 https://www.ncbi.nlm.nih.gov/pubmed/33706940
Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency. Crouse RB, Kim K, Batchelor HM, Girardi EM, Kamaletdinova R, Chan J, Rajebhosale P, Pittenger ST, Role LW, Talmage DA, Jing M, Li Y, Gao XB, Mineur YS, Picciotto MR eLife 32945260 Elife 2020 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/32945260
Functionally refined encoding of threat memory by distinct populations of basal forebrain cholinergic projection neurons. Rajebhosale P, Ananth MR, Kim R, Crouse R, Jiang L, López-Hernández G, Zhong C, Arty C, Wang S, Jone A, Desai NS, Li Y, Picciotto MR, Role LW, Talmage DA eLife 38363713 Elife 2024 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/38363713
Hippocampal knockdown of α2 nicotinic or M1 muscarinic acetylcholine receptors in C57BL/6J male mice impairs cued fear conditioning. Mineur YS, Ernstsen C, Islam A, Lefoli Maibom K, Picciotto MR Genes, brain, and behavior 32447811 Genes Brain Behav 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32447811
Cumulative Effects of Social Stress on Reward-Guided Actions and Prefrontal Cortical Activity. Barthas F, Hu MY, Siniscalchi MJ, Ali F, Mineur YS, Picciotto MR, Kwan AC Biological psychiatry 32276717 Biol Psychiatry 2020 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/32276717
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The following article for this Special Issue was previously published and can be found in its respective issue online: "How can I measure brain acetylcholine levels in vivo? Advantages and caveats of commonly used approaches". Journal of neurochemistry 38607971 J Neurochem 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38607971
ACh signaling modulates activity of the GABAergic signaling network in the basolateral amygdala and behavior in stress-relevant paradigms. Mineur YS, Mose TN, Maibom KL, Pittenger ST, Soares AR, Wu H, Taylor SR, Huang Y, Picciotto MR Molecular psychiatry 36050437 Mol Psychiatry 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36050437
Sex differences in stress-induced alcohol intake: a review of preclinical studies focused on amygdala and inflammatory pathways. Mineur YS, Garcia-Rivas V, Thomas MA, Soares AR, McKee SA, Picciotto MR Psychopharmacology 35359158 Psychopharmacology (Berl) 2022 Jul https://www.ncbi.nlm.nih.gov/pubmed/35359158
Sex Differences in the Ventral Tegmental Area and Nucleus Accumbens Proteome at Baseline and Following Nicotine Exposure. Lee AM, Mansuri MS, Wilson RS, Lam TT, Nairn AC, Picciotto MR Frontiers in molecular neuroscience 34335180 Front Mol Neurosci 2021 https://www.ncbi.nlm.nih.gov/pubmed/34335180
microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity. Horie T, Nakao T, Miyasaka Y, Nishino T, Matsumura S, Nakazeki F, Ide Y, Kimura M, Tsuji S, Rodriguez RR, Watanabe T, Yamasaki T, Xu S, Otani C, Miyagawa S, Matsushita K, Sowa N, Omori A, Tanaka J, Nishimura C, Nishiga M, Kuwabara Y, Baba O, Watanabe S, Nishi H, Nakashima Y, Picciotto MR, Inoue H, Watanabe D, Nakamura K, Sasaki T, Kimura T, Ono K Nature communications 33594062 Nat Commun 2021 Feb 16 https://www.ncbi.nlm.nih.gov/pubmed/33594062
Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward. Zhou WL, Kim K, Ali F, Pittenger ST, Calarco CA, Mineur YS, Ramakrishnan C, Deisseroth K, Kwan AC, Picciotto MR Science advances 36260661 Sci Adv 2022 Oct 21 https://www.ncbi.nlm.nih.gov/pubmed/36260661
How can I measure brain acetylcholine levels in vivo? Advantages and caveats of commonly used approaches. Mineur YS, Picciotto MR Journal of neurochemistry 37621094 J Neurochem 2023 Oct https://www.ncbi.nlm.nih.gov/pubmed/37621094
Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice. Tan Y, Hang F, Liu ZW, Stoiljkovic M, Wu M, Tu Y, Han W, Lee AM, Kelley C, Hajós M, Lu L, de Lecea L, De Araujo I, Picciotto MR, Horvath TL, Gao XB The Journal of clinical investigation 32516139 J Clin Invest 2020 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/32516139
Origin and Function of Stress-Induced IL-6 in Murine Models. Qing H, Desrouleaux R, Israni-Winger K, Mineur YS, Fogelman N, Zhang C, Rashed S, Palm NW, Sinha R, Picciotto MR, Perry RJ, Wang A Cell 32610084 Cell 2020 Jul 23 https://www.ncbi.nlm.nih.gov/pubmed/32610084
Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs. Mineur YS, Mose TN, Vanopdenbosch L, Etherington IM, Ogbejesi C, Islam A, Pineda CM, Crouse RB, Zhou W, Thompson DC, Bentham MP, Picciotto MR Molecular psychiatry 34997190 Mol Psychiatry 2022 Mar https://www.ncbi.nlm.nih.gov/pubmed/34997190
Nicotine addiction: More than just dopamine. Kim K, Picciotto MR Current opinion in neurobiology 37832393 Curr Opin Neurobiol 2023 Dec https://www.ncbi.nlm.nih.gov/pubmed/37832393
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Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model. Blaeser AS, Zhao J, Sugden AU, Carneiro-Nascimento S, Andermann ML, Levy D bioRxiv : the preprint server for biology 37577675 bioRxiv 2023 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/37577675
Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions. Jeong H, Namboodiri VMK, Jung MW, Andermann ML bioRxiv : the preprint server for biology 36993665 bioRxiv 2023 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/36993665
A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution. Nardone S, De Luca R, Zito A, Klymko N, Nicoloutsopoulos D, Amsalem O, Brannigan C, Resch JM, Jacobs CL, Pant D, Veregge M, Srinivasan H, Grippo RM, Yang Z, Zeidel ML, Andermann ML, Harris KD, Tsai LT, Arrigoni E, Verstegen AMJ, Saper CB, Lowell BB bioRxiv : the preprint server for biology 38014113 bioRxiv 2023 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/38014113
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Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions. Narunsky-Haziza L, Sepich-Poore GD, Livyatan I, Asraf O, Martino C, Nejman D, Gavert N, Stajich JE, Amit G, González A, Wandro S, Perry G, Ariel R, Meltser A, Shaffer JP, Zhu Q, Balint-Lahat N, Barshack I, Dadiani M, Gal-Yam EN, Patel SP, Bashan A, Swafford AD, Pilpel Y, Knight R, Straussman R Cell 36179670 Cell 2022 Sep 29 https://www.ncbi.nlm.nih.gov/pubmed/36179670
Implementation of Practical Surface SARS-CoV-2 Surveillance in School Settings. Cantú VJ, Belda-Ferre P, Salido RA, Tsai R, Austin B, Jordan W, Asudani M, Walster A, Magallanes CG, Valentine H, Manjoonian A, Wijaya C, Omaleki V, Sanders K, Aigner S, Baer NA, Betty M, Castro-Martínez A, Cheung W, Crescini ES, De Hoff P, Eisner E, Hakim A, Kapadia B, Lastrella AL, Lawrence ES, Ngo TT, Ostrander T, Sathe S, Seaver P, Smoot EW, Carlin AF, Yeo GW, Laurent LC, Manlutac AL, Fielding-Miller R, Knight R mSystems 35703437 mSystems 2022 Aug 30 https://www.ncbi.nlm.nih.gov/pubmed/35703437
Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission. Karthikeyan S, Levy JI, De Hoff P, Humphrey G, Birmingham A, Jepsen K, Farmer S, Tubb HM, Valles T, Tribelhorn CE, Tsai R, Aigner S, Sathe S, Moshiri N, Henson B, Mark AM, Hakim A, Baer NA, Barber T, Belda-Ferre P, Chacón M, Cheung W, Cresini ES, Eisner ER, Lastrella AL, Lawrence ES, Marotz CA, Ngo TT, Ostrander T, Plascencia A, Salido RA, Seaver P, Smoot EW, McDonald D, Neuhard RM, Scioscia AL, Satterlund AM, Simmons EH, Abelman DB, Brenner D, Bruner JC, Buckley A, Ellison M, Gattas J, Gonias SL, Hale M, Hawkins F, Ikeda L, Jhaveri H, Johnson T, Kellen V, Kremer B, Matthews G, McLawhon RW, Ouillet P, Park D, Pradenas A, Reed S, Riggs L, Sanders A, Sollenberger B, Song A, White B, Winbush T, Aceves CM, Anderson C, Gangavarapu K, Hufbauer E, Kurzban E, Lee J, Matteson NL, Parker E, Perkins SA, Ramesh KS, Robles-Sikisaka R, Schwab MA, Spencer E, Wohl S, Nicholson L, McHardy IH, Dimmock DP, Hobbs CA, Bakhtar O, Harding A, Mendoza A, Bolze A, Becker D, Cirulli ET, Isaksson M, Schiabor Barrett KM, Washington NL, Malone JD, Schafer AM, Gurfield N, Stous S, Fielding-Miller R, Garfein RS, Gaines T, Anderson C, Martin NK, Schooley R, Austin B, MacCannell DR, Kingsmore SF, Lee W, Shah S, McDonald E, Yu AT, Zeller M, Fisch KM, Longhurst C, Maysent P, Pride D, Khosla PK, Laurent LC, Yeo GW, Andersen KG, Knight R Nature 35798029 Nature 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/35798029
Chemically informed analyses of metabolomics mass spectrometry data with Qemistree. Tripathi A, Vázquez-Baeza Y, Gauglitz JM, Wang M, Dührkop K, Nothias-Esposito M, Acharya DD, Ernst M, van der Hooft JJJ, Zhu Q, McDonald D, Brejnrod AD, Gonzalez A, Handelsman J, Fleischauer M, Ludwig M, Böcker S, Nothias LF, Knight R, Dorrestein PC Nature chemical biology 33199911 Nat Chem Biol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/33199911
A Sensitive, Rapid, and Portable CasRx-based Diagnostic Assay for SARS-CoV-2. Brogan DJ, Chaverra-Rodriguez D, Lin CP, Smidler AL, Yang T, Alcantara LM, Antoshechkin I, Liu J, Raban RR, Belda-Ferre P, Knight R, Komives EA, Akbari OS medRxiv : the preprint server for health sciences 33106816 medRxiv 2020 Oct 20 https://www.ncbi.nlm.nih.gov/pubmed/33106816
Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic. Vrbanac A, Patras KA, Jarmusch AK, Mills RH, Shing SR, Quinn RA, Vargas F, Gonzalez DJ, Dorrestein PC, Knight R, Nizet V mSystems 33024048 mSystems 2020 Oct 6 https://www.ncbi.nlm.nih.gov/pubmed/33024048
Determination of Effect Sizes for Power Analysis for Microbiome Studies Using Large Microbiome Databases. Rahman G, McDonald D, Gonzalez A, Vázquez-Baeza Y, Jiang L, Casals-Pascual C, Hakim D, Dilmore AH, Nowinski B, Peddada S, Knight R Genes 37372419 Genes (Basel) 2023 Jun 9 https://www.ncbi.nlm.nih.gov/pubmed/37372419
Greengenes2 unifies microbial data in a single reference tree. McDonald D, Jiang Y, Balaban M, Cantrell K, Zhu Q, Gonzalez A, Morton JT, Nicolaou G, Parks DH, Karst SM, Albertsen M, Hugenholtz P, DeSantis T, Song SJ, Bartko A, Havulinna AS, Jousilahti P, Cheng S, Inouye M, Niiranen T, Jain M, Salomaa V, Lahti L, Mirarab S, Knight R Nature biotechnology 37500913 Nat Biotechnol 2024 May https://www.ncbi.nlm.nih.gov/pubmed/37500913
Real-time, multi-pathogen wastewater genomic surveillance with Freyja 2. Levy JI, Gangavarapu P, Pilz DA, Jesvaghane MA, Steedman A, Zeller M, Gangavarapu K, McDonald D, Libuit K, Kapsak C, Young EL, Agrawal S, Orschler L, Hölzer M, Stachler E, Park DJ, Hinrichs AS, Laurent LC, Knight R, Andersen KG medRxiv : the preprint server for health sciences 40778124 medRxiv 2025 Jul 27 https://www.ncbi.nlm.nih.gov/pubmed/40778124
Blood microbial DNA signature differentiates hepatocellular carcinoma from metastatic lesions. Guccione C, Dantas Machado AC, Youssef F, Angeli-Pahim I, Duarte S, Warren C, Farmer S, Humphrey G, Richter RA, McDonald D, Weng Y, Burgoyne A, Loomba R, Curtius K, Zarrinpar A, Knight R, Zarrinpar A eGastroenterology 40843454 eGastroenterology 2025 https://www.ncbi.nlm.nih.gov/pubmed/40843454
Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission. Karthikeyan S, Levy JI, De Hoff P, Humphrey G, Birmingham A, Jepsen K, Farmer S, Tubb HM, Valles T, Tribelhorn CE, Tsai R, Aigner S, Sathe S, Moshiri N, Henson B, Mark AM, Hakim A, Baer NA, Barber T, Belda-Ferre P, Chacón M, Cheung W, Cresini ES, Eisner ER, Lastrella AL, Lawrence ES, Marotz CA, Ngo TT, Ostrander T, Plascencia A, Salido RA, Seaver P, Smoot EW, McDonald D, Neuhard RM, Scioscia AL, Satterlund AM, Simmons EH, Abelman DB, Brenner D, Bruner JC, Buckley A, Ellison M, Gattas J, Gonias SL, Hale M, Hawkins F, Ikeda L, Jhaveri H, Johnson T, Kellen V, Kremer B, Matthews G, McLawhon RW, Ouillet P, Park D, Pradenas A, Reed S, Riggs L, Sanders A, Sollenberger B, Song A, White B, Winbush T, Aceves CM, Anderson C, Gangavarapu K, Hufbauer E, Kurzban E, Lee J, Matteson NL, Parker E, Perkins SA, Ramesh KS, Robles-Sikisaka R, Schwab MA, Spencer E, Wohl S, Nicholson L, Mchardy IH, Dimmock DP, Hobbs CA, Bakhtar O, Harding A, Mendoza A, Bolze A, Becker D, Cirulli ET, Isaksson M, Barrett KMS, Washington NL, Malone JD, Schafer AM, Gurfield N, Stous S, Fielding-Miller R, Garfein RS, Gaines T, Anderson C, Martin NK, Schooley R, Austin B, MacCannell DR, Kingsmore SF, Lee W, Shah S, McDonald E, Yu AT, Zeller M, Fisch KM, Longhurst C, Maysent P, Pride D, Khosla PK, Laurent LC, Yeo GW, Andersen KG, Knight R medRxiv : the preprint server for health sciences 35411350 medRxiv 2022 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/35411350
A comparison of six DNA extraction protocols for 16S, ITS and shotgun metagenomic sequencing of microbial communities. Shaffer JP, Carpenter CS, Martino C, Salido RA, Minich JJ, Bryant M, Sanders K, Schwartz T, Humphrey G, Swafford AD, Knight R BioTechniques 35713407 Biotechniques 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35713407
Enhancing untargeted metabolomics using metadata-based source annotation. Gauglitz JM, West KA, Bittremieux W, Williams CL, Weldon KC, Panitchpakdi M, Di Ottavio F, Aceves CM, Brown E, Sikora NC, Jarmusch AK, Martino C, Tripathi A, Meehan MJ, Dorrestein K, Shaffer JP, Coras R, Vargas F, Goldasich LD, Schwartz T, Bryant M, Humphrey G, Johnson AJ, Spengler K, Belda-Ferre P, Diaz E, McDonald D, Zhu Q, Elijah EO, Wang M, Marotz C, Sprecher KE, Vargas-Robles D, Withrow D, Ackermann G, Herrera L, Bradford BJ, Marques LMM, Amaral JG, Silva RM, Veras FP, Cunha TM, Oliveira RDR, Louzada-Junior P, Mills RH, Piotrowski PK, Servetas SL, Da Silva SM, Jones CM, Lin NJ, Lippa KA, Jackson SA, Daouk RK, Galasko D, Dulai PS, Kalashnikova TI, Wittenberg C, Terkeltaub R, Doty MM, Kim JH, Rhee KE, Beauchamp-Walters J, Wright KP Jr, Dominguez-Bello MG, Manary M, Oliveira MF, Boland BS, Lopes NP, Guma M, Swafford AD, Dutton RJ, Knight R, Dorrestein PC Nature biotechnology 35798960 Nat Biotechnol 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/35798960
Global chemical effects of the microbiome include new bile-acid conjugations. Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC Nature 32103176 Nature 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/32103176
Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity. Martino C, Kellman BP, Sandoval DR, Clausen TM, Marotz CA, Song SJ, Wandro S, Zaramela LS, Salido Benítez RA, Zhu Q, Armingol E, Vázquez-Baeza Y, McDonald D, Sorrentino JT, Taylor B, Belda-Ferre P, Liang C, Zhang Y, Schifanella L, Klatt NR, Havulinna AS, Jousilahti P, Huang S, Haiminen N, Parida L, Kim HC, Swafford AD, Zengler K, Cheng S, Inouye M, Niiranen T, Jain M, Salomaa V, Esko JD, Lewis NE, Knight R bioRxiv : the preprint server for biology 32839779 bioRxiv 2020 Aug 18 https://www.ncbi.nlm.nih.gov/pubmed/32839779
Context-aware dimensionality reduction deconvolutes gut microbial community dynamics. Martino C, Shenhav L, Marotz CA, Armstrong G, McDonald D, Vázquez-Baeza Y, Morton JT, Jiang L, Dominguez-Bello MG, Swafford AD, Halperin E, Knight R Nature biotechnology 32868914 Nat Biotechnol 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/32868914
Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity. Shaffer JP, Nothias LF, Thompson LR, Sanders JG, Salido RA, Couvillion SP, Brejnrod AD, Lejzerowicz F, Haiminen N, Huang S, Lutz HL, Zhu Q, Martino C, Morton JT, Karthikeyan S, Nothias-Esposito M, Dührkop K, Böcker S, Kim HW, Aksenov AA, Bittremieux W, Minich JJ, Marotz C, Bryant MM, Sanders K, Schwartz T, Humphrey G, Vásquez-Baeza Y, Tripathi A, Parida L, Carrieri AP, Beck KL, Das P, González A, McDonald D, Ladau J, Karst SM, Albertsen M, Ackermann G, DeReus J, Thomas T, Petras D, Shade A, Stegen J, Song SJ, Metz TO, Swafford AD, Dorrestein PC, Jansson JK, Gilbert JA, Knight R, Earth Microbiome Project 500 (EMP500) Consortium Nature microbiology 36443458 Nat Microbiol 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36443458
The Gut Microbial Bile Acid Modulation and Its Relevance to Digestive Health and Diseases. Fogelson KA, Dorrestein PC, Zarrinpar A, Knight R Gastroenterology 36841488 Gastroenterology 2023 Jun https://www.ncbi.nlm.nih.gov/pubmed/36841488
Robustness of cancer microbiome signals over a broad range of methodological variation. Sepich-Poore GD, McDonald D, Kopylova E, Guccione C, Zhu Q, Austin G, Carpenter C, Fraraccio S, Wandro S, Kosciolek T, Janssen S, Metcalf JL, Song SJ, Kanbar J, Miller-Montgomery S, Heaton R, Mckay R, Patel SP, Swafford AD, Korem T, Knight R Oncogene 38396294 Oncogene 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38396294
TEMPTED: time-informed dimensionality reduction for longitudinal microbiome studies. Shi P, Martino C, Han R, Janssen S, Buck G, Serrano M, Owzar K, Knight R, Shenhav L, Zhang AR Genome biology 39696594 Genome Biol 2024 Dec 19 https://www.ncbi.nlm.nih.gov/pubmed/39696594
SARS-CoV-2 infectivity can be modulated through bacterial grooming of the glycocalyx. Martino C, Kellman BP, Sandoval DR, Clausen TM, Cooper R, Benjdia A, Soualmia F, Clark AE, Garretson AF, Marotz CA, Song SJ, Wandro S, Zaramela LS, Salido RA, Zhu Q, Armingol E, Vázquez-Baeza Y, McDonald D, Sorrentino JT, Taylor B, Belda-Ferre P, Das P, Ali F, Liang C, Zhang Y, Schifanella L, Covizzi A, Lai A, Riva A, Basting C, Broedlow CA, Havulinna AS, Jousilahti P, Estaki M, Kosciolek T, Kuplicki R, Victor TA, Paulus MP, Savage KE, Benbow JL, Spielfogel ES, Anderson CAM, Martinez ME, Lacey JV Jr, Huang S, Haiminen N, Parida L, Kim H-C, Gilbert JA, Sweeney DA, Allard SM, Swafford AD, Cheng S, Inouye M, Niiranen T, Jain M, Salomaa V, Zengler K, Klatt NR, Hasty J, Berteau O, Carlin AF, Esko JD, Lewis NE, Knight R mBio 39998226 mBio 2025 Apr 9 https://www.ncbi.nlm.nih.gov/pubmed/39998226
The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns. Salido RA, Zhao HN, McDonald D, Mannochio-Russo H, Zuffa S, Oles RE, Aron AT, El Abiead Y, Farmer S, González A, Martino C, Mohanty I, Parker CW, Patel L, Portal Gomes PW, Schmid R, Schwartz T, Zhu J, Barratt MR, Rubins KH, Chu H, Karouia F, Venkateswaran K, Dorrestein PC, Knight R Cell 40020666 Cell 2025 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/40020666
Streamlined extraction of nucleic acids and metabolites from low- and high-biomass samples using isopropanol and matrix tubes. Brennan C, Shaffer JP, Belda-Ferre P, Mohanty I, Weng Y, Cantrell K, Ackermann G, Allaband C, Bryant M, Farmer S, González A, McDonald D, Martino C, Meehan MJ, Rahman G, Salido RA, Schwartz T, Song SJ, Tribelhorn C, Tubb HM, Dorrestein PC, Knight R Microbiology spectrum 41070991 Microbiol Spectr 2025 Nov 4 https://www.ncbi.nlm.nih.gov/pubmed/41070991
Calculating fast differential genome coverages among metagenomic sources using micov. Weng Y, Guccione C, McDonald D, Oles R, Devkota S, Kopylova E, Sepich-Poore GD, Salido RA, Din MO, Song SJ, Curtius K, Chu H, Bartko A, Hasty J, Knight R Communications biology 41266796 Commun Biol 2025 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/41266796
Metatranscriptomics Uncover Diurnal Functional Shifts in Bacterial Transgenes with Profound Metabolic Effects. Ramos SF, Siguenza N, Zhong W, Mohanty I, Lingaraju A, Richter RA, Karthikeyan S, Lukowski AL, Zhu Q, Nunes WDG, Zemlin J, Xu ZZ, Hasty J, Dorrestein PC, Panda S, Knight R, Zarrinpar A Cell host & microbe 40777923 Cell Host Microbe 2025 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/40777923
Phylogeny-Aware Analysis of Metagenome Community Ecology Based on Matched Reference Genomes while Bypassing Taxonomy. Zhu Q, Huang S, Gonzalez A, McGrath I, McDonald D, Haiminen N, Armstrong G, Vázquez-Baeza Y, Yu J, Kuczynski J, Sepich-Poore GD, Swafford AD, Das P, Shaffer JP, Lejzerowicz F, Belda-Ferre P, Havulinna AS, Méric G, Niiranen T, Lahti L, Salomaa V, Kim HC, Jain M, Inouye M, Gilbert JA, Knight R mSystems 35369727 mSystems 2022 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/35369727
Compositionally Aware Phylogenetic Beta-Diversity Measures Better Resolve Microbiomes Associated with Phenotype. Martino C, McDonald D, Cantrell K, Dilmore AH, Vázquez-Baeza Y, Shenhav L, Shaffer JP, Rahman G, Armstrong G, Allaband C, Song SJ, Knight R mSystems 35477286 mSystems 2022 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/35477286
Candidate probiotic Lactiplantibacillus plantarum HNU082 rapidly and convergently evolves within human, mice, and zebrafish gut but differentially influences the resident microbiome. Huang S, Jiang S, Huo D, Allaband C, Estaki M, Cantu V, Belda-Ferre P, Vázquez-Baeza Y, Zhu Q, Ma C, Li C, Zarrinpar A, Liu YY, Knight R, Zhang J Microbiome 34193290 Microbiome 2021 Jun 30 https://www.ncbi.nlm.nih.gov/pubmed/34193290
Zebra: Static and Dynamic Genome Cover Thresholds with Overlapping References. Hakim D, Wandro S, Zengler K, Zaramela LS, Nowinski B, Swafford A, Zhu Q, Song SJ, Gonzalez A, McDonald D, Knight R mSystems 36073806 mSystems 2022 Oct 26 https://www.ncbi.nlm.nih.gov/pubmed/36073806
A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data. Zuffa S, Schmid R, Bauermeister A, Gomes PWP, Caraballo-Rodriguez AM, Abiead YE, Aron AT, Gentry EC, Zemlin J, Meehan MJ, Avalon NE, Cichewicz RH, Buzun E, Terrazas MC, Hsu CY, Oles R, Ayala AV, Zhao J, Chu H, Kuijpers MCM, Jackrel SL, Tugizimana F, Nephali LP, Dubery IA, Madala NE, Moreira EA, Costa-Lotufo LV, Lopes NP, Rezende-Teixeira P, Jimenez PC, Rimal B, Patterson AD, Traxler MF, de Cassia Pessotti R, Alvarado-Villalobos D, Tamayo-Castillo G, Chaverri P, Escudero-Leyva E, Quiros-Guerrero LM, Bory AJ, Joubert J, Rutz A, Wolfender JL, Allard PM, Sichert A, Pontrelli S, Pullman BS, Bandeira N, Gerwick WH, Gindro K, Massana-Codina J, Wagner BC, Forchhammer K, Petras D, Aiosa N, Garg N, Liebeke M, Bourceau P, Kang KB, Gadhavi H, de Carvalho LPS, Dos Santos MS, Pérez-Lorente AI, Molina-Santiago C, Romero D, Franke R, Brönstrup M, de León AVP, Pope PB, Rosa SL, Barbera G, Roager HM, Laursen MF, Hammerle F, Siewert B, Peintner U, Licona-Cassani C, Rodriguez-Orduña L, Rampler E, Hildebrand F, Koellensperger G, Schoeny H, Hohenwallner K, Panzenboeck L, Gregor R, O'Neill EC, Roxborough ET, Odoi J, Bale NJ, Ding S, Sinninghe Damsté JS, Guan XL, Cui JJ, Ju KS, Silva DB, Silva FMR, da Silva GF, Koolen HHF, Grundmann C, Clement JA, Mohimani H, Broders K, McPhail KL, Ober-Singleton SE, Rath CM, McDonald D, Knight R, Wang M, Dorrestein PC Research square 37577622 Res Sq 2023 Aug 3 https://www.ncbi.nlm.nih.gov/pubmed/37577622
Maximizing the potential of high-throughput next-generation sequencing through precise normalization based on read count distribution. Brennan C, Salido RA, Belda-Ferre P, Bryant M, Cowart C, Tiu MD, González A, McDonald D, Tribelhorn C, Zarrinpar A, Knight R mSystems 37350611 mSystems 2023 Aug 31 https://www.ncbi.nlm.nih.gov/pubmed/37350611
Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data. Guccione C, Patel L, Tomofuji Y, McDonald D, Gonzalez A, Sepich-Poore GD, Sonehara K, Zakeri M, Chen Y, Dilmore AH, Damle N, Baranzini SE, Nakatsuji T, Gallo RL, Langmead B, Okada Y, Curtius K, Knight R Research square 39502785 Res Sq 2024 Oct 23 https://www.ncbi.nlm.nih.gov/pubmed/39502785
Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data. Guccione C, Patel L, Tomofuji Y, McDonald D, Gonzalez A, Sepich-Poore GD, Sonehara K, Zakeri M, Chen Y, Dilmore AH, Damle N, Baranzini SE, Hightower G, Nakatsuji T, Gallo RL, Langmead B, Okada Y, Curtius K, Knight R Nature communications 39827261 Nat Commun 2025 Jan 18 https://www.ncbi.nlm.nih.gov/pubmed/39827261
Temporal nutrition analysis associates dietary regularity and quality with gut microbiome diversity: insights from the Food & You digital cohort. Singh R, McDonald D, Hernandez AR, Song SJ, Bartko A, Knight R, Salathé M Nature communications 41028733 Nat Commun 2025 Sep 30 https://www.ncbi.nlm.nih.gov/pubmed/41028733
SARS-CoV-2 Distribution in Residential Housing Suggests Contact Deposition and Correlates with Rothia sp. Cantú VJ, Salido RA, Huang S, Rahman G, Tsai R, Valentine H, Magallanes CG, Aigner S, Baer NA, Barber T, Belda-Ferre P, Betty M, Bryant M, Casas Maya M, Castro-Martínez A, Chacón M, Cheung W, Crescini ES, De Hoff P, Eisner E, Farmer S, Hakim A, Kohn L, Lastrella AL, Lawrence ES, Morgan SC, Ngo TT, Nouri A, Plascencia A, Ruiz CA, Sathe S, Seaver P, Shwartz T, Smoot EW, Ostrander RT, Valles T, Yeo GW, Laurent LC, Fielding-Miller R, Knight R mSystems 35575492 mSystems 2022 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/35575492
Naturalization of the microbiota developmental trajectory of Cesarean-born neonates after vaginal seeding. Song SJ, Wang J, Martino C, Jiang L, Thompson WK, Shenhav L, McDonald D, Marotz C, Harris PR, Hernandez CD, Henderson N, Ackley E, Nardella D, Gillihan C, Montacuti V, Schweizer W, Jay M, Combellick J, Sun H, Garcia-Mantrana I, Gil Raga F, Collado MC, Rivera-Viñas JI, Campos-Rivera M, Ruiz-Calderon JF, Knight R, Dominguez-Bello MG Med (New York, N.Y.) 35590169 Med 2021 Aug 13 https://www.ncbi.nlm.nih.gov/pubmed/35590169
Optimizing UniFrac with OpenACC Yields Greater Than One Thousand Times Speed Increase. Sfiligoi I, Armstrong G, Gonzalez A, McDonald D, Knight R mSystems 35638356 mSystems 2022 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/35638356
Applications and Comparison of Dimensionality Reduction Methods for Microbiome Data. Armstrong G, Rahman G, Martino C, McDonald D, Gonzalez A, Mishne G, Knight R Frontiers in bioinformatics 36304280 Front Bioinform 2022 https://www.ncbi.nlm.nih.gov/pubmed/36304280
Cancer's second genome: Microbial cancer diagnostics and redefining clonal evolution as a multispecies process: Humans and their tumors are not aseptic, and the multispecies nature of cancer modulates clinical care and clonal evolution: Humans and their tumors are not aseptic, and the multispecies nature of cancer modulates clinical care and clonal evolution. Sepich-Poore GD, Guccione C, Laplane L, Pradeu T, Curtius K, Knight R BioEssays : news and reviews in molecular, cellular and developmental biology 35253252 Bioessays 2022 May https://www.ncbi.nlm.nih.gov/pubmed/35253252
Microbial context predicts SARS-CoV-2 prevalence in patients and the hospital built environment. Marotz C, Belda-Ferre P, Ali F, Das P, Huang S, Cantrell K, Jiang L, Martino C, Diner RE, Rahman G, McDonald D, Armstrong G, Kodera S, Donato S, Ecklu-Mensah G, Gottel N, Garcia MCS, Chiang LY, Salido RA, Shaffer JP, Bryant M, Sanders K, Humphrey G, Ackermann G, Haiminen N, Beck KL, Kim HC, Carrieri AP, Parida L, Vázquez-Baeza Y, Torriani FJ, Knight R, Gilbert JA, Sweeney DA, Allard SM medRxiv : the preprint server for health sciences 33236030 medRxiv 2020 Nov 22 https://www.ncbi.nlm.nih.gov/pubmed/33236030
Host variables confound gut microbiota studies of human disease. Vujkovic-Cvijin I, Sklar J, Jiang L, Natarajan L, Knight R, Belkaid Y Nature 33149306 Nature 2020 Nov https://www.ncbi.nlm.nih.gov/pubmed/33149306
A comparison of DNA/RNA extraction protocols for high-throughput sequencing of microbial communities. Shaffer JP, Marotz C, Belda-Ferre P, Martino C, Wandro S, Estaki M, Salido RA, Carpenter CS, Zaramela LS, Minich JJ, Bryant M, Sanders K, Fraraccio S, Ackermann G, Humphrey G, Swafford AD, Miller-Montgomery S, Knight R BioTechniques 33512248 Biotechniques 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33512248
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The changing metabolic landscape of bile acids - keys to metabolism and immune regulation. Mohanty I, Allaband C, Mannochio-Russo H, El Abiead Y, Hagey LR, Knight R, Dorrestein PC Nature reviews. Gastroenterology & hepatology 38575682 Nat Rev Gastroenterol Hepatol 2024 Jul https://www.ncbi.nlm.nih.gov/pubmed/38575682
Bayesian multivariate sparse functional principal components analysis with application to longitudinal microbiome multiomics data. Jiang L, Elrod C, Kim JJ, Swafford AD, Knight R, Thompson WK The annals of applied statistics 40969773 Ann Appl Stat 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/40969773
Generation of accurate, expandable phylogenomic trees with uDance. Balaban M, Jiang Y, Zhu Q, McDonald D, Knight R, Mirarab S Nature biotechnology 37500914 Nat Biotechnol 2024 May https://www.ncbi.nlm.nih.gov/pubmed/37500914
Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression. Fu T, Huan T, Rahman G, Zhi H, Xu Z, Oh TG, Guo J, Coulter S, Tripathi A, Martino C, McCarville JL, Zhu Q, Cayabyab F, Low B, He M, Xing S, Vargas F, Yu RT, Atkins A, Liddle C, Ayres J, Raffatellu M, Dorrestein PC, Downes M, Knight R, Evans RM Cell reports 37611587 Cell Rep 2023 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/37611587
Improving microbial phylogeny with citizen science within a mass-market video game. Sarrazin-Gendron R, Ghasemloo Gheidari P, Butyaev A, Keding T, Cai E, Zheng J, Mutalova R, Mounthanyvong J, Zhu Y, Nazarova E, Drogaris C, Erhart K, Borderlands Science Development Team, Borderlands Science players, Brouillette A, Richard G, Pitchford R, Caisse S, Blanchette M, McDonald D, Knight R, Szantner A, Waldispühl J Nature biotechnology 38622344 Nat Biotechnol 2025 Jan https://www.ncbi.nlm.nih.gov/pubmed/38622344
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Development of Tripolymeric Triaxial Electrospun Fibrous Matrices for Dual Drug Delivery Applications. Nagiah N, Murdock CJ, Bhattacharjee M, Nair L, Laurencin CT Scientific reports 31953439 Sci Rep 2020 Jan 17 https://www.ncbi.nlm.nih.gov/pubmed/31953439
Ultra-low binder content 3D printed calcium phosphate graphene scaffolds as resorbable, osteoinductive matrices that support bone formation in vivo. Daneshmandi L, Holt BD, Arnold AM, Laurencin CT, Sydlik SA Scientific reports 35484292 Sci Rep 2022 Apr 28 https://www.ncbi.nlm.nih.gov/pubmed/35484292
Muscle degeneration in chronic massive rotator cuff tears of the shoulder: Addressing the real problem using a graphene matrix. Saveh Shemshaki N, Kan HM, Barajaa M, Otsuka T, Lebaschi A, Mishra N, Nair LS, Laurencin CT Proceedings of the National Academy of Sciences of the United States of America 35939692 Proc Natl Acad Sci U S A 2022 Aug 16 https://www.ncbi.nlm.nih.gov/pubmed/35939692
Regenerative Engineering Animal Models for Knee Osteoarthritis. Esdaille CJ, Ude CC, Laurencin CT Regenerative engineering and translational medicine 35958163 Regen Eng Transl Med 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35958163
Animal models of osteoarthritis: classification, update, and measurement of outcomes. Kuyinu EL, Narayanan G, Nair LS, Laurencin CT Journal of orthopaedic surgery and research 26837951 J Orthop Surg Res 2016 Feb 2 https://www.ncbi.nlm.nih.gov/pubmed/26837951
Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering. Narayanan G, Vernekar VN, Kuyinu EL, Laurencin CT Advanced drug delivery reviews 27125191 Adv Drug Deliv Rev 2016 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/27125191
An American Crisis: the Lack of Black Men in Medicine. Laurencin CT, Murray M Journal of racial and ethnic health disparities 28534304 J Racial Ethn Health Disparities 2017 Jun https://www.ncbi.nlm.nih.gov/pubmed/28534304
REGENERATIVE ENGINEERING: APPROACHES TO LIMB REGENERATION AND OTHER GRAND CHALLENGES. Laurencin CT, Nair LS Regenerative engineering and translational medicine 26985451 Regen Eng Transl Med 2015 Apr 1 https://www.ncbi.nlm.nih.gov/pubmed/26985451
Regenerative Engineering of Cartilage Using Adipose-Derived Stem Cells. Kasir R, Vernekar VN, Laurencin CT Regenerative engineering and translational medicine 26998511 Regen Eng Transl Med 2015 Dec 1 https://www.ncbi.nlm.nih.gov/pubmed/26998511
Growth factor delivery strategies for rotator cuff repair and regeneration. Prabhath A, Vernekar VN, Sanchez E, Laurencin CT International journal of pharmaceutics 29317260 Int J Pharm 2018 Jun 15 https://www.ncbi.nlm.nih.gov/pubmed/29317260
The Treatment of Muscle Atrophy after Rotator Cuff Tears Using Electroconductive Nanofibrous Matrices. Tang X, Shemshaki NS, Vernekar VN, Prabhath A, Kuyinu E, Kan HM, Barajaa M, Khan Y, Laurencin CT Regenerative engineering and translational medicine 33816776 Regen Eng Transl Med 2021 Mar https://www.ncbi.nlm.nih.gov/pubmed/33816776
Kinetic degradation and biocompatibility evaluation of polycaprolactone-based biologics delivery matrices for regenerative engineering of the rotator cuff. Prabhath A, Vernekar VN, Vasu V, Badon M, Avochinou JE, Asandei AD, Kumbar SG, Weber E, Laurencin CT Journal of biomedical materials research. Part A 33974735 J Biomed Mater Res A 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/33974735
Preparation and characterization of amnion hydrogel and its synergistic effect with adipose derived stem cells towards IL1β activated chondrocytes. Bhattacharjee M, Ivirico JLE, Kan HM, Bordett R, Pandey R, Otsuka T, Nair LS, Laurencin CT Scientific reports 33127964 Sci Rep 2020 Oct 30 https://www.ncbi.nlm.nih.gov/pubmed/33127964
Mechanically superior matrices promote osteointegration and regeneration of anterior cruciate ligament tissue in rabbits. Mengsteab PY, Otsuka T, McClinton A, Shemshaki NS, Shah S, Kan HM, Obopilwe E, Vella AT, Nair LS, Laurencin CT Proceedings of the National Academy of Sciences of the United States of America 33144508 Proc Natl Acad Sci U S A 2020 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/33144508
Biomimetic electroconductive nanofibrous matrices for skeletal muscle regenerative engineering. Tang X, Saveh-Shemshaki N, Kan HM, Khan Y, Laurencin CT Regenerative engineering and translational medicine 33426269 Regen Eng Transl Med 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/33426269
Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies. Escobar Ivirico JL, Bhattacharjee M, Kuyinu E, Nair LS, Laurencin CT Engineering (Beijing, China) 35392109 Engineering (Beijing) 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/35392109
Ligament Regenerative Engineering: Braiding Scalable and Tunable Bioengineered Ligaments Using a Bench-Top Braiding Machine. Mengsteab PY, Freeman J, Barajaa MA, Nair LS, Laurencin CT Regenerative engineering and translational medicine 35005216 Regen Eng Transl Med 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/35005216
Harnessing cAMP signaling in musculoskeletal regenerative engineering. Ifegwu OC, Awale G, Rajpura K, Lo KW, Laurencin CT Drug discovery today 28359841 Drug Discov Today 2017 Jul https://www.ncbi.nlm.nih.gov/pubmed/28359841
Generational Biodegradable and Regenerative Polyphosphazene Polymers and their Blends with Poly (lactic-co-glycolic acid). Ogueri KS, Allcock HR, Laurencin CT Progress in polymer science 31551636 Prog Polym Sci 2019 Nov https://www.ncbi.nlm.nih.gov/pubmed/31551636
Biodegradable Polyphosphazene-Based Blends for Regenerative Engineering. Ogueri KS, Escobar Ivirico JL, Nair LS, Allcock HR, Laurencin CT Regenerative engineering and translational medicine 28596987 Regen Eng Transl Med 2017 Mar https://www.ncbi.nlm.nih.gov/pubmed/28596987
Engineered stem cell niche matrices for rotator cuff tendon regenerative engineering. Peach MS, Ramos DM, James R, Morozowich NL, Mazzocca AD, Doty SB, Allcock HR, Kumbar SG, Laurencin CT PloS one 28369135 PLoS One 2017 https://www.ncbi.nlm.nih.gov/pubmed/28369135
The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche. Seyedhassantehrani N, Otsuka T, Singh S, Gardiner DM Current stem cell reports 29230380 Curr Stem Cell Rep 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/29230380
Fabrication and characterization of mechanically competent 3D printed polycaprolactone-reduced graphene oxide scaffolds. Seyedsalehi A, Daneshmandi L, Barajaa M, Riordan J, Laurencin CT Scientific reports 33335152 Sci Rep 2020 Dec 17 https://www.ncbi.nlm.nih.gov/pubmed/33335152
Bioinspired Scaffold Designs for Regenerating Musculoskeletal Tissue Interfaces. Barajaa MA, Nair LS, Laurencin CT Regenerative engineering and translational medicine 33344758 Regen Eng Transl Med 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33344758
Stromal Vascular Fraction for Osteoarthritis of the Knee Regenerative Engineering. Ude CC, Shah S, Ogueri KS, Nair LS, Laurencin CT Regenerative engineering and translational medicine 35958164 Regen Eng Transl Med 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35958164
Nanofiber Technology for Regenerative Engineering. Ogueri KS, Laurencin CT ACS nano 32678581 ACS Nano 2020 Aug 25 https://www.ncbi.nlm.nih.gov/pubmed/32678581
Synthesis, Physicochemical Analysis, and Side Group Optimization of Degradable Dipeptide-Based Polyphosphazenes as Potential Regenerative Biomaterials. Ogueri KS, Escobar Ivirico JL, Li Z, Blumenfield RH, Allcock HR, Laurencin CT ACS applied polymer materials 32699835 ACS Appl Polym Mater 2019 Jun 14 https://www.ncbi.nlm.nih.gov/pubmed/32699835
Polyphosphazene polymers: The next generation of biomaterials for regenerative engineering and therapeutic drug delivery. Ogueri KS, Ogueri KS, Allcock HR, Laurencin CT Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B 32309041 J Vac Sci Technol B Nanotechnol Microelectron 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32309041
Enhancing the Surface Properties of a Bioengineered Anterior Cruciate Ligament Matrix for Use with Point-of-Care Stem Cell Therapy. Yu X, Mengsteab PY, Narayanan G, Nair LS, Laurencin CT Engineering (Beijing, China) 34136308 Engineering (Beijing) 2021 Feb https://www.ncbi.nlm.nih.gov/pubmed/34136308
Injectable amnion hydrogel-mediated delivery of adipose-derived stem cells for osteoarthritis treatment. Bhattacharjee M, Escobar Ivirico JL, Kan HM, Shah S, Otsuka T, Bordett R, Barajaa M, Nagiah N, Pandey R, Nair LS, Laurencin CT Proceedings of the National Academy of Sciences of the United States of America 35046053 Proc Natl Acad Sci U S A 2022 Jan 25 https://www.ncbi.nlm.nih.gov/pubmed/35046053
The Role of Nanomaterials and Biological Agents on Rotator Cuff Regeneration. Washington KS, Shemshaki NS, Laurencin CT Regenerative engineering and translational medicine 35005215 Regen Eng Transl Med 2021 Dec https://www.ncbi.nlm.nih.gov/pubmed/35005215
In Vivo Evaluation of the Regenerative Capability of Glycylglycine Ethyl Ester-Substituted Polyphosphazene and Poly(lactic-co-glycolic acid) Blends: A Rabbit Critical-Sized Bone Defect Model. Ogueri KS, Ogueri KS, McClinton A, Kan HM, Ude CC, Barajaa MA, Allcock HR, Laurencin CT ACS biomaterials science & engineering 33792283 ACS Biomater Sci Eng 2021 Apr 12 https://www.ncbi.nlm.nih.gov/pubmed/33792283
Regenerative engineering: a review of recent advances and future directions. Esdaille CJ, Washington KS, Laurencin CT Regenerative medicine 34030463 Regen Med 2021 May https://www.ncbi.nlm.nih.gov/pubmed/34030463
Regenerative Engineering of the Rotator Cuff of the Shoulder. Narayanan G, Nair LS, Laurencin CT ACS biomaterials science & engineering 33418763 ACS Biomater Sci Eng 2018 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/33418763
Addressing Justified Vaccine Hesitancy in the Black Community. Laurencin CT Journal of racial and ethnic health disparities 33783755 J Racial Ethn Health Disparities 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33783755
Biomedical applications of polyphosphazenes. Ogueri KS, Ogueri KS, Ude CC, Allcock HR, Laurencin CT Medical devices & sensors 33889811 Med Devices Sens 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33889811
The past, present and future of ligament regenerative engineering. Mengsteab PY, Nair LS, Laurencin CT Regenerative medicine 27879170 Regen Med 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27879170
Identification of Heparan-Sulfate Rich Cells in the Loose Connective Tissues of the Axolotl (Ambystoma mexicanum) with the Potential to Mediate Growth Factor Signaling during Regeneration. Otsuka T, Phan AQ, Laurencin CT, Esko JD, Bryant SV, Gardiner DM Regenerative engineering and translational medicine 33748405 Regen Eng Transl Med 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/33748405
Skeletal Muscle Regenerative Engineering. Tang X, Daneshmandi L, Awale G, Nair LS, Laurencin CT Regenerative engineering and translational medicine 33778155 Regen Eng Transl Med 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/33778155
Graphene-Based Biomaterials for Bone Regenerative Engineering: A Comprehensive Review of the Field and Considerations Regarding Biocompatibility and Biodegradation. Daneshmandi L, Barajaa M, Tahmasbi Rad A, Sydlik SA, Laurencin CT Advanced healthcare materials 33103370 Adv Healthc Mater 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33103370
Spatial alignment of 3D printed scaffolds modulates genotypic expression in pre-osteoblasts. Nagiah N, Bhattacharjee M, Murdock CJ, Kan HM, Barajaa M, Laurencin CT Materials letters 32773913 Mater Lett 2020 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/32773913
Regenerative Cell-Based Therapies: Cutting Edge, Bleeding Edge, and Off the Edge. Laurencin CT, McClinton A Regenerative engineering and translational medicine 33344756 Regen Eng Transl Med 2020 Mar https://www.ncbi.nlm.nih.gov/pubmed/33344756
Nail matrix regenerative engineering: in vitro evaluation of poly(lactide-co-glycolide)/gelatin fibrous substrates. Montgomery AB, McClinton A, Nair L, Laurencin CT Journal of biomedical materials research. Part A 31981298 J Biomed Mater Res A 2020 May https://www.ncbi.nlm.nih.gov/pubmed/31981298
Nanofiber/Microsphere Hybrid Matrices In Vivo for Bone Regenerative Engineering: A Preliminary Report. Nelson C, Khan Y, Laurencin CT Regenerative engineering and translational medicine 30687776 Regen Eng Transl Med 2018 Sep https://www.ncbi.nlm.nih.gov/pubmed/30687776
Overexpression of NDST1 Attenuates Fibrotic Response in Murine Adipose-Derived Stem Cells. Otsuka T, Kan HM, Mason TD, Nair LS, Laurencin CT Stem cells and development 35920108 Stem Cells Dev 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/35920108
Efficacy of a Novel Electroconductive Matrix To Treat Muscle Atrophy and Fat Accumulation in Chronic Massive Rotator Cuff Tears of the Shoulder. Shemshaki NS, Kan HM, Barajaa MA, Lebaschi A, Otsuka T, Mishra N, Nair LS, Laurencin CT ACS biomaterials science & engineering 37769114 ACS Biomater Sci Eng 2023 Oct 9 https://www.ncbi.nlm.nih.gov/pubmed/37769114
Microsphere-Based Scaffolds in Regenerative Engineering. Gupta V, Khan Y, Berkland CJ, Laurencin CT, Detamore MS Annual review of biomedical engineering 28633566 Annu Rev Biomed Eng 2017 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/28633566
Regulation of regeneration by Heparan Sulfate Proteoglycans in the Extracellular Matrix. Gardiner DM Regenerative engineering and translational medicine 29242821 Regen Eng Transl Med 2017 Sep https://www.ncbi.nlm.nih.gov/pubmed/29242821
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Regenerative Engineering and Bionic Limbs. James R, Laurencin CT Rare metals 25983525 Rare Metals 2015 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/25983525
Phosphate graphene as an intrinsically osteoinductive scaffold for stem cell-driven bone regeneration. Arnold AM, Holt BD, Daneshmandi L, Laurencin CT, Sydlik SA Proceedings of the National Academy of Sciences of the United States of America 30796184 Proc Natl Acad Sci U S A 2019 Mar 12 https://www.ncbi.nlm.nih.gov/pubmed/30796184
The Mechanism of Metallosis After Total Hip Arthroplasty. Ude CC, Esdaille CJ, Ogueri KS, Ho-Man K, Laurencin SJ, Nair LS, Laurencin CT Regenerative engineering and translational medicine 35530571 Regen Eng Transl Med 2021 Sep https://www.ncbi.nlm.nih.gov/pubmed/35530571
Evaluation of a bioengineered ACL matrix's osteointegration with BMP-2 supplementation. Mengsteab PY, Conroy P, Badon M, Otsuka T, Kan HM, Vella AT, Nair LS, Laurencin CT PloS one 31910231 PLoS One 2020 https://www.ncbi.nlm.nih.gov/pubmed/31910231
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POLYMERIC BIOMATERIALS FOR SCAFFOLD-BASED BONE REGENERATIVE ENGINEERING. Ogueri KS, Jafari T, Escobar Ivirico JL, Laurencin CT Regenerative engineering and translational medicine 31423461 Regen Eng Transl Med 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31423461
Robust phenotypic maintenance of limb cells during heterogeneous culture in a physiologically relevant polymeric-based constructed graft system. Barajaa MA, Nair LS, Laurencin CT Scientific reports 32678185 Sci Rep 2020 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/32678185
A Regenerative Polymer Blend Composed of Glycylglycine ethyl ester-substituted Polyphosphazene and Poly (lactic-co-glycolic acid). Ogueri KS, Ogueri KS, Allcock HR, Laurencin CT ACS applied polymer materials 32699836 ACS Appl Polym Mater 2020 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/32699836
A Pandemic on a Pandemic: Racism and COVID-19 in Blacks. Laurencin CT, Walker JM Cell systems 32702320 Cell Syst 2020 Jul 22 https://www.ncbi.nlm.nih.gov/pubmed/32702320
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The synthetic artificial stem cell (SASC): Shifting the paradigm of cell therapy in regenerative engineering. Shah S, Esdaille CJ, Bhattacharjee M, Kan HM, Laurencin CT Proceedings of the National Academy of Sciences of the United States of America 34987101 Proc Natl Acad Sci U S A 2022 Jan 11 https://www.ncbi.nlm.nih.gov/pubmed/34987101
Corrosion of Metals During Use in Arthroplasty. Ude CC, Dzidotor GK, Iloeje K, Nair LS, Laurencin CT ACS applied bio materials 37261398 ACS Appl Bio Mater 2023 Jun 19 https://www.ncbi.nlm.nih.gov/pubmed/37261398
Hyaluronic acid-British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis. Ude CC, Schmidt SJ, Laurencin S, Shah S, Esdaille J, Kan HM, Holt BD, Arnold AM, Wolf ME, Nair LS, Sydlik SA, Laurencin CT Proceedings of the National Academy of Sciences of the United States of America 37903261 Proc Natl Acad Sci U S A 2023 Nov 7 https://www.ncbi.nlm.nih.gov/pubmed/37903261
Fibroblast growth factor 8b (FGF-8b) enhances myogenesis and inhibits adipogenesis in rotator cuff muscle cell populations in vitro. Otsuka T, Kan HM, Mengsteab PY, Tyson B, Laurencin CT Proceedings of the National Academy of Sciences of the United States of America 38147545 Proc Natl Acad Sci U S A 2024 Jan 2 https://www.ncbi.nlm.nih.gov/pubmed/38147545
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Nanobody-based CAR NK cells for possible immunotherapy of MICA(+) tumors. Verhaar ER, van Keizerswaard WJC, Knoflook A, Balligand T, Ploegh HL PNAS nexus 38756234 PNAS Nexus 2024 May https://www.ncbi.nlm.nih.gov/pubmed/38756234
Growth inhibition of Saccharomyces cerevisiae by SUMO-specific nanobodies. Suresh P, Jim SZ, Sahay I, Tang AY, Wijne C, Gan J, Pishesha N, Avalos JL, Ploegh H Scientific reports 40419540 Sci Rep 2025 May 26 https://www.ncbi.nlm.nih.gov/pubmed/40419540
Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer immunotherapy. Liu X, Le Gall C, Alexander RK, Borgman E, Balligand T, Ploegh HL Nature biomedical engineering 40670719 Nat Biomed Eng 2026 Jan https://www.ncbi.nlm.nih.gov/pubmed/40670719
Antigen discovery tools for adaptive immune receptor repertoire research. Bousbaine D, Ploegh HL Current opinion in systems biology 33195881 Curr Opin Syst Biol 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33195881
MICA-specific nanobodies for diagnosis and immunotherapy of MICA(+) tumors. Verhaar ER, Knoflook A, Pishesha N, Liu X, van Keizerswaard WJC, Wucherpfennig KW, Ploegh HL Frontiers in immunology 38550583 Front Immunol 2024 https://www.ncbi.nlm.nih.gov/pubmed/38550583
Nanobodies as non-invasive imaging tools. Rashidian M, Ploegh H Immuno-oncology technology 35754459 Immunooncol Technol 2020 Sep https://www.ncbi.nlm.nih.gov/pubmed/35754459
An armed anti-immunoglobulin light chain nanobody protects mice against influenza A and B infections. Liu X, Balligand T, Carpenet C, Ploegh HL Science immunology 37352373 Sci Immunol 2023 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/37352373
Induction of antigen-specific tolerance by nanobody-antigen adducts that target class-II major histocompatibility complexes. Pishesha N, Harmand T, Smeding LY, Ma W, Ludwig LS, Janssen R, Islam A, Xie YJ, Fang T, McCaul N, Pinney W 3rd, Sugito HR, Rossotti MA, Gonzalez-Sapienza G, Ploegh HL Nature biomedical engineering 34127819 Nat Biomed Eng 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/34127819
A modular Uba1-nanobody fusion enables selective ubiquitin transfer to tagged E2 enzymes. Wijne C, D'Amico F, Pérez Berrocal DA, Mulder MPC, Ploegh HL, Gan J The Journal of biological chemistry 41203132 J Biol Chem 2025 Dec https://www.ncbi.nlm.nih.gov/pubmed/41203132
Identification and characterization of nanobodies specific for the human ubiquitin-like ISG15 protein. Gan J, Dabhade P, Wijne C, McKibben W, Draganov SD, Alrawili H, Sun ZJ, Houghton JW, Tate EW, Le Gall C, Suresh P, Pishesha N, Pinto-Fernández A, Schwartz TU, Ploegh HL The Journal of biological chemistry 40774387 J Biol Chem 2025 Sep https://www.ncbi.nlm.nih.gov/pubmed/40774387
A monoclonal anti-hemagglutinin stem antibody modified with zanamivir protects against both influenza A and B viruses. Liu X, Balligand T, Le Gall C, Ploegh HL Proceedings of the National Academy of Sciences of the United States of America 40193611 Proc Natl Acad Sci U S A 2025 Apr 15 https://www.ncbi.nlm.nih.gov/pubmed/40193611
A nanobody that binds to the backside of the ubiquitin conjugating enzyme Ube2G2 differentially affects interactions with its partner E3 Ligases. Suresh P, Wijne C, Sun ZJ, Becht N, Sahay I, Pishesha N, Ploegh H Communications biology 40234692 Commun Biol 2025 Apr 16 https://www.ncbi.nlm.nih.gov/pubmed/40234692
Asparaginyl Ligase-Catalyzed One-Step Cell Surface Modification of Red Blood Cells. Harmand TJ, Pishesha N, Rehm FBH, Ma W, Pinney WB, Xie YJ, Ploegh HL ACS chemical biology 34129316 ACS Chem Biol 2021 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/34129316
A monoclonal antibody that recognizes a unique 13-residue epitope in the cytoplasmic tail of HLA-E. Verhaar ER, Gan J, Buhl S, Li Z, Horowitz A, Ploegh HL Molecular immunology 38901180 Mol Immunol 2024 Aug https://www.ncbi.nlm.nih.gov/pubmed/38901180
Bi-specific antibody engagers for cancer immunotherapy. Ploegh H, Liu X, Le Gall C, Alexander R, Borgman E, Balligand T Research square 39149504 Res Sq 2024 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/39149504
Improved GPCR ligands from nanobody tethering. Cheloha RW, Fischer FA, Woodham AW, Daley E, Suminski N, Gardella TJ, Ploegh HL Nature communications 32350260 Nat Commun 2020 Apr 29 https://www.ncbi.nlm.nih.gov/pubmed/32350260
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USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism. Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, Sapmaz A Proceedings of the National Academy of Sciences of the United States of America 38055744 Proc Natl Acad Sci U S A 2023 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/38055744
Surviving COVID-19: A disease tolerance perspective. Ayres JS Science advances 32494691 Sci Adv 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32494691
A metabolic handbook for the COVID-19 pandemic. Ayres JS Nature metabolism 32694793 Nat Metab 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32694793
Cooperative defenses during enteropathogenic infection. Troha K, Ayres JS Current opinion in microbiology 34847524 Curr Opin Microbiol 2022 Feb https://www.ncbi.nlm.nih.gov/pubmed/34847524
Immunometabolism of infections. Ayres JS Nature reviews. Immunology 31892735 Nat Rev Immunol 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31892735
Fluoxetine promotes immunometabolic defenses to mediate host-pathogen cooperation during sepsis. Gallant RM, Snyder JM, Ayres JS bioRxiv : the preprint server for biology 38013994 bioRxiv 2023 Nov 18 https://www.ncbi.nlm.nih.gov/pubmed/38013994
Beyond tug-of-war: Iron metabolism in cooperative host-microbe interactions. Chen GY, Ayres JS PLoS pathogens 32785251 PLoS Pathog 2020 Aug https://www.ncbi.nlm.nih.gov/pubmed/32785251
Age-dependent roles of cardiac remodeling in sepsis defense and pathogenesis. Sanchez KK, McCarville JL, Stengel SJ, Snyder JM, Williams AE, Ayres JS bioRxiv : the preprint server for biology 36993409 bioRxiv 2023 Mar 15 https://www.ncbi.nlm.nih.gov/pubmed/36993409
Microbiota Metabolites in Health and Disease. McCarville JL, Chen GY, Cuevas VD, Troha K, Ayres JS Annual review of immunology 32340573 Annu Rev Immunol 2020 Apr 26 https://www.ncbi.nlm.nih.gov/pubmed/32340573
The Biology of Physiological Health. Ayres JS Cell 32302569 Cell 2020 Apr 16 https://www.ncbi.nlm.nih.gov/pubmed/32302569
Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. Chen GY, Thorup NR, Miller AJ, Li YC, Ayres JS bioRxiv : the preprint server for biology 36711884 bioRxiv 2023 Feb 26 https://www.ncbi.nlm.nih.gov/pubmed/36711884
Pre-infection cerebral cortex structure predicts murine sepsis outcome. Gallant RM, Alam S, Venkataraman K, McKenna BS, Khairy K, Ayres JS PloS one 40961093 PLoS One 2025 https://www.ncbi.nlm.nih.gov/pubmed/40961093
Disease tolerance and infection pathogenesis age-related tradeoffs in mice. Sanchez KK, McCarville JL, Stengel SJ, Snyder JM, Williams AE, Ayres JS Nature 41535469 Nature 2026 Feb https://www.ncbi.nlm.nih.gov/pubmed/41535469
Metabolic Adaptations to Infections at the Organismal Level. Troha K, Ayres JS Trends in immunology 31959515 Trends Immunol 2020 Feb https://www.ncbi.nlm.nih.gov/pubmed/31959515
Chronic Leptin Deficiency Improves Tolerance of Physiological Damage and Host-Pathogen Cooperation during Yersinia pseudotuberculosis Infection. Sanchez KK, Troha K, Mu A, Redford SE, McCarville JL, Insenga A, Stengel S, Lee YM, Ayres JS Infection and immunity 35924898 Infect Immun 2022 Sep 15 https://www.ncbi.nlm.nih.gov/pubmed/35924898
Adipose triglyceride lipase mediates lipolysis and lipid mobilization in response to iron-mediated negative energy balance. Romero AR, Mu A, Ayres JS iScience 35265813 iScience 2022 Mar 18 https://www.ncbi.nlm.nih.gov/pubmed/35265813
Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. Chen GY, Thorup NR, Miller AJ, Li YC, Ayres JS Science advances 37352357 Sci Adv 2023 Jun 23 https://www.ncbi.nlm.nih.gov/pubmed/37352357
CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection. Redford SE, Varanasi SK, Sanchez KK, Thorup NR, Ayres JS Cell reports 37490905 Cell Rep 2023 Aug 29 https://www.ncbi.nlm.nih.gov/pubmed/37490905
Fluoxetine promotes IL-10-dependent metabolic defenses to protect from sepsis-induced lethality. Gallant RM, Sanchez KK, Joulia E, Snyder JM, Metallo CM, Ayres JS Science advances 39951524 Sci Adv 2025 Feb 14 https://www.ncbi.nlm.nih.gov/pubmed/39951524
Dietary methionine mitigates immune-mediated damage by enhancing renal clearance of cytokines. Troha K, Kambhampati S, Insenga A, Metallo CM, Ayres JS Cell metabolism 41576934 Cell Metab 2026 Feb 3 https://www.ncbi.nlm.nih.gov/pubmed/41576934
Tunable dynamics of B cell selection in gut germinal centres. Nowosad CR, Mesin L, Castro TBR, Wichmann C, Donaldson GP, Araki T, Schiepers A, Lockhart AAK, Bilate AM, Mucida D, Victora GD Nature 33116306 Nature 2020 Dec https://www.ncbi.nlm.nih.gov/pubmed/33116306
Universal recording of cell-cell contacts in vivo for interaction-based transcriptomics. Nakandakari-Higa S, Canesso MCC, Walker S, Chudnovskiy A, Jacobsen JT, Bilanovic J, Parigi SM, Fiedorczuk K, Fuchs E, Bilate AM, Pasqual G, Mucida D, Pritykin Y, Victora GD bioRxiv : the preprint server for biology 36993443 bioRxiv 2023 Apr 18 https://www.ncbi.nlm.nih.gov/pubmed/36993443
Molecular fate-mapping of serum antibody responses to repeat immunization. Schiepers A, van 't Wout MFL, Greaney AJ, Zang T, Muramatsu H, Lin PJC, Tam YK, Mesin L, Starr TN, Bieniasz PD, Pardi N, Bloom JD, Victora GD Nature 36646114 Nature 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/36646114
Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting. Mesin L, Schiepers A, Ersching J, Barbulescu A, Cavazzoni CB, Angelini A, Okada T, Kurosaki T, Victora GD Cell 31866068 Cell 2020 Jan 9 https://www.ncbi.nlm.nih.gov/pubmed/31866068
Monitoring the Interaction Between Dendritic Cells and T Cells In Vivo with LIPSTIC. Pasqual G, Chudnovskiy A, Victora GD Methods in molecular biology (Clifton, N.J.) 36905509 Methods Mol Biol 2023 https://www.ncbi.nlm.nih.gov/pubmed/36905509
Universal recording of immune cell interactions in vivo. Nakandakari-Higa S, Walker S, Canesso MCC, van der Heide V, Chudnovskiy A, Kim DY, Jacobsen JT, Parsa R, Bilanovic J, Parigi SM, Fiedorczuk K, Fuchs E, Bilate AM, Pasqual G, Mucida D, Kamphorst AO, Pritykin Y, Victora GD Nature 38448581 Nature 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38448581
Opposing effects of pre-existing antibody and memory T cell help on the dynamics of recall germinal centers. Schiepers A, van 't Wout MFL, Hobbs A, Mesin L, Victora GD bioRxiv : the preprint server for biology 38168231 bioRxiv 2023 Dec 15 https://www.ncbi.nlm.nih.gov/pubmed/38168231
Opposing effects of pre-existing antibody and memory T cell help on the dynamics of recall germinal centers. Schiepers A, Van't Wout MFL, Hobbs A, Mesin L, Victora GD Immunity 38838672 Immunity 2024 Jul 9 https://www.ncbi.nlm.nih.gov/pubmed/38838672
Studying interactions between dendritic cells and T cells in vivo. Chudnovskiy A, Pasqual G, Victora GD Current opinion in immunology 30884422 Curr Opin Immunol 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/30884422
Expression of Foxp3 by T follicular helper cells in end-stage germinal centers. Jacobsen JT, Hu W, R Castro TB, Solem S, Galante A, Lin Z, Allon SJ, Mesin L, Bilate AM, Schiepers A, Shalek AK, Rudensky AY, Victora GD Science (New York, N.Y.) 34437125 Science 2021 Jul 16 https://www.ncbi.nlm.nih.gov/pubmed/34437125
Clonal replacement sustains long-lived germinal centers primed by respiratory viruses. de Carvalho RVH, Ersching J, Barbulescu A, Hobbs A, Castro TBR, Mesin L, Jacobsen JT, Phillips BK, Hoffmann HH, Parsa R, Canesso MCC, Nowosad CR, Feng A, Leist SR, Baric RS, Yang E, Utz PJ, Victora GD Cell 36565697 Cell 2023 Jan 5 https://www.ncbi.nlm.nih.gov/pubmed/36565697
Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses. Castaño D, Bettini E, Kumar B, Chudnovskiy A, Siv A, Protti G, Nakadakari-Higa S, Ceglia S, De Luna N, Chiu JE, Lederer K, Li SH, Ibrahim H, Muramatsu H, Mdluli T, Abraham E, Sahingur SE, Maillard I, Tam YK, Shin S, Hensley SE, Miner JJ, Lipinszki Z, Reboldi A, Pardi N, Spreafico R, Victora GD, Locci M Cell 41406961 Cell 2025 Dec 24 https://www.ncbi.nlm.nih.gov/pubmed/41406961
Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells. Pae J, Ersching J, Castro TBR, Schips M, Mesin L, Allon SJ, Ordovas-Montanes J, Mlynarczyk C, Melnick A, Efeyan A, Shalek AK, Meyer-Hermann M, Victora GD The Journal of experimental medicine 33332554 J Exp Med 2021 Apr 5 https://www.ncbi.nlm.nih.gov/pubmed/33332554
Identification of antigen-presenting cell-T cell interactions driving immune responses to food. Campos Canesso MC, de Castro TBR, Nakandakari-Higa S, Lockhart A, Luehr J, Bortolatto J, Parsa R, Esterházy D, Lyu M, Liu TT, Murphy KM, Sonnenberg GF, Reis BS, Victora GD, Mucida D Science (New York, N.Y.) 39700315 Science 2025 Mar 14 https://www.ncbi.nlm.nih.gov/pubmed/39700315
Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4(+) T cell response. Chudnovskiy A, Castro TBR, Nakandakari-Higa S, Cui A, Lin CH, Sade-Feldman M, Phillips BK, Pae J, Mesin L, Bortolatto J, Schweitzer LD, Pasqual G, Lu LF, Hacohen N, Victora GD Science immunology 39365874 Sci Immunol 2024 Oct 4 https://www.ncbi.nlm.nih.gov/pubmed/39365874
IL-17-producing γδ T cells protect against Clostridium difficile infection. Chen YS, Chen IB, Pham G, Shao TY, Bangar H, Way SS, Haslam DB The Journal of clinical investigation 31990686 J Clin Invest 2020 May 1 https://www.ncbi.nlm.nih.gov/pubmed/31990686
Maternal-fetal conflict averted by progesterone- induced FOXP3+ regulatory T cells. Severance AL, Kinder JM, Xin L, Burg AR, Shao TY, Pham G, Tilburgs T, Goodman WA, Mesiano S, Way SS iScience 35637736 iScience 2022 Jun 17 https://www.ncbi.nlm.nih.gov/pubmed/35637736
Pregnancy enables antibody protection against intracellular infection. Erickson JJ, Archer-Hartmann S, Yarawsky AE, Miller JLC, Seveau S, Shao TY, Severance AL, Miller-Handley H, Wu Y, Pham G, Wasik BR, Parrish CR, Hu YC, Lau JTY, Azadi P, Herr AB, Way SS Nature 35676476 Nature 2022 Jun https://www.ncbi.nlm.nih.gov/pubmed/35676476
Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications. Deshmukh H, Way SS Annual review of pathology 30183507 Annu Rev Pathol 2019 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/30183507
Immunology of Uterine and Vaginal Mucosae: (Trends in Immunology 39, 302-314, 2018). Zhou JZ, Way SS, Chen K Trends in immunology 29530651 Trends Immunol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29530651
Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. Turner LH, Kinder JM, Wilburn A, D'Mello RJ, Braunlin MR, Jiang TT, Pham G, Way SS PLoS pathogens 29145516 PLoS Pathog 2017 Nov https://www.ncbi.nlm.nih.gov/pubmed/29145516
Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. Yang JD, Mott D, Sutiwisesak R, Lu YJ, Raso F, Stowell B, Babunovic GH, Lee J, Carpenter SM, Way SS, Fortune SM, Behar SM PLoS pathogens 29782535 PLoS Pathog 2018 Feb https://www.ncbi.nlm.nih.gov/pubmed/29782535
A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice. Deshpande NR, Uhrlaub JL, Way SS, Nikolich-Žugich J, Kuhns MS PloS one 29864157 PLoS One 2018 https://www.ncbi.nlm.nih.gov/pubmed/29864157
Mouse models of neutropenia reveal progenitor-stage-specific defects. Muench DE, Olsson A, Ferchen K, Pham G, Serafin RA, Chutipongtanate S, Dwivedi P, Song B, Hay S, Chetal K, Trump-Durbin LR, Mookerjee-Basu J, Zhang K, Yu JC, Lutzko C, Myers KC, Nazor KL, Greis KD, Kappes DJ, Way SS, Salomonis N, Grimes HL Nature 32494068 Nature 2020 Jun https://www.ncbi.nlm.nih.gov/pubmed/32494068
Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity. Eshleman EM, Shao TY, Woo V, Rice T, Engleman L, Didriksen BJ, Whitt J, Haslam DB, Way SS, Alenghat T The Journal of clinical investigation 36602872 J Clin Invest 2023 Feb 15 https://www.ncbi.nlm.nih.gov/pubmed/36602872
Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses. Shao TY, Ang WXG, Jiang TT, Huang FS, Andersen H, Kinder JM, Pham G, Burg AR, Ruff B, Gonzalez T, Khurana Hershey GK, Haslam DB, Way SS Cell host & microbe 30870622 Cell Host Microbe 2019 Mar 13 https://www.ncbi.nlm.nih.gov/pubmed/30870622
TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2. Kotov DI, Mitchell JS, Pengo T, Ruedl C, Way SS, Langlois RA, Fife BT, Jenkins MK Journal of immunology (Baltimore, Md. : 1950) 30858199 J Immunol 2019 May 1 https://www.ncbi.nlm.nih.gov/pubmed/30858199
Reproductive outcomes after pregnancy-induced displacement of preexisting microchimeric cells. Shao TY, Kinder JM, Harper G, Pham G, Peng Y, Liu J, Gregory EJ, Sherman BE, Wu Y, Iten AE, Hu YC, Russi AE, Erickson JJ, Miller-Handley H, Way SS Science (New York, N.Y.) 37733857 Science 2023 Sep 22 https://www.ncbi.nlm.nih.gov/pubmed/37733857
Diffuse neuroinflammation and immature neuron loss in fetal Rhesus macaques after short-term intrauterine infection. Presicce P, Beckman D, Diniz GB, Cappelletti M, Ott S, Bercovici S, Kale S, Babb P, Mohole J, Richardson LS, Kammala AK, Menon R, Miller LA, Crouch EE, Jobe AH, Divanovic S, Chougnet CA, Way SS, Morrison JH, Kallapur SG Journal of neuroinflammation 41535926 J Neuroinflammation 2026 Jan 15 https://www.ncbi.nlm.nih.gov/pubmed/41535926
Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria. Jiang TT, Shao TY, Ang WXG, Kinder JM, Turner LH, Pham G, Whitt J, Alenghat T, Way SS Cell host & microbe 29174402 Cell Host Microbe 2017 Dec 13 https://www.ncbi.nlm.nih.gov/pubmed/29174402
Vaccination strategies to enhance immunity in neonates. Kollmann TR, Marchant A, Way SS Science (New York, N.Y.) 32381718 Science 2020 May 8 https://www.ncbi.nlm.nih.gov/pubmed/32381718
Tacrolimus exposure windows responsible for Listeria monocytogenes infection susceptibility. Miller-Handley H, Erickson JJ, Gregory EJ, Prasanphanich NS, Shao TY, Way SS Transplant infectious disease : an official journal of the Transplantation Society 34057792 Transpl Infect Dis 2021 Aug https://www.ncbi.nlm.nih.gov/pubmed/34057792
Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. DiToro D, Winstead CJ, Pham D, Witte S, Andargachew R, Singer JR, Wilson CG, Zindl CL, Luther RJ, Silberger DJ, Weaver BT, Kolawole EM, Martinez RJ, Turner H, Hatton RD, Moon JJ, Way SS, Evavold BD, Weaver CT Science (New York, N.Y.) 30213884 Science 2018 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/30213884
Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation. Shao TY, Jiang TT, Stevens J, Russi AE, Troutman TD, Bernieh A, Pham G, Erickson JJ, Eshleman EM, Alenghat T, Jameson SC, Hogquist KA, Weaver CT, Haslam DB, Deshmukh H, Way SS Cell reports 37889750 Cell Rep 2023 Nov 28 https://www.ncbi.nlm.nih.gov/pubmed/37889750
Resilient anatomy and local plasticity of naive and stress haematopoiesis. Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson CB, Zhang YS, Turcotte R, Alt C, Ito K, Homan S, Sherman BE, Shao TY, Slaughter A, Weinhaus B, Song B, Filippi MD, Grimes HL, Lin CP, Ito K, Way SS, Kofron JM, Lucas D Nature 38509363 Nature 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38509363
Maternal Vaccination to Prevent Adverse Pregnancy Outcomes: An Underutilized Molecular Immunological Intervention? Giles ML, Way SS, Marchant A, Aghaepour N, James T, Schaltz-Buchholzer F, Zazara D, Arck P, Kollmann TR Journal of molecular biology 37080422 J Mol Biol 2023 Jul 1 https://www.ncbi.nlm.nih.gov/pubmed/37080422
Immunological implications of pregnancy-induced microchimerism. Kinder JM, Stelzer IA, Arck PC, Way SS Nature reviews. Immunology 28480895 Nat Rev Immunol 2017 Aug https://www.ncbi.nlm.nih.gov/pubmed/28480895
Immunology of the Uterine and Vaginal Mucosae. Zhou JZ, Way SS, Chen K Trends in immunology 29433961 Trends Immunol 2018 Apr https://www.ncbi.nlm.nih.gov/pubmed/29433961
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Genomic mapping of DNA-repair reaction intermediates in living cells with engineered DNA structure-trap proteins. Liu J, Mei Q, Nimer S, Fitzgerald DM, Rosenberg SM Methods in enzymology 34776211 Methods Enzymol 2021 https://www.ncbi.nlm.nih.gov/pubmed/34776211
Biology before the SOS Response-DNA Damage Mechanisms at Chromosome Fragile Sites. Fitzgerald DM, Rosenberg SM Cells 34571923 Cells 2021 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/34571923
Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. Byun J, Han Y, Li Y, Xia J, Long E, Choi J, Xiao X, Zhu M, Zhou W, Sun R, Bossé Y, Song Z, Schwartz A, Lusk C, Rafnar T, Stefansson K, Zhang T, Zhao W, Pettit RW, Liu Y, Li X, Zhou H, Walsh KM, Gorlov I, Gorlova O, Zhu D, Rosenberg SM, Pinney S, Bailey-Wilson JE, Mandal D, de Andrade M, Gaba C, Willey JC, You M, Anderson M, Wiencke JK, Albanes D, Lam S, Tardon A, Chen C, Goodman G, Bojeson S, Brenner H, Landi MT, Chanock SJ, Johansson M, Muley T, Risch A, Wichmann HE, Bickeböller H, Christiani DC, Rennert G, Arnold S, Field JK, Shete S, Le Marchand L, Melander O, Brunnstrom H, Liu G, Andrew AS, Kiemeney LA, Shen H, Zienolddiny S, Grankvist K, Johansson M, Caporaso N, Cox A, Hong YC, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Patel A, Lan Q, Rothman N, Taylor F, Kachuri L, Witte JS, Sakoda LC, Spitz M, Brennan P, Lin X, McKay J, Hung RJ, Amos CI Nature genetics 35915169 Nat Genet 2022 Aug https://www.ncbi.nlm.nih.gov/pubmed/35915169
Rapid profiling of DNA replication dynamics using mass spectrometry-based analysis of nascent DNA. Ashour ME, Byrum AK, Meroni A, Xia J, Singh S, Galletto R, Rosenberg SM, Vindigni A, Mosammaparast N The Journal of cell biology 36795402 J Cell Biol 2023 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/36795402
IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. Xu L, Peng F, Luo Q, Ding Y, Yuan F, Zheng L, He W, Zhang SS, Fu X, Liu J, Mutlu AS, Wang S, Nehring RB, Li X, Tang Q, Li C, Lv X, Dobrolecki LE, Zhang W, Han D, Zhao N, Jaehnig E, Wang J, Wu W, Graham DA, Li Y, Chen R, Peng W, Chen Y, Catic A, Zhang Z, Zhang B, Mustoe AM, Koong AC, Miles G, Lewis MT, Wang MC, Rosenberg SM, O'Malley BW, Westbrook TF, Xu H, Zhang XH, Osborne CK, Li JB, Ellis MJ, Rimawi MF, Rosen JM, Chen X Cell 39419025 Cell 2024 Dec 12 https://www.ncbi.nlm.nih.gov/pubmed/39419025
Stress-Induced Mutagenesis, Gambler Cells, and Stealth Targeting Antibiotic-Induced Evolution. Pribis JP, Zhai Y, Hastings PJ, Rosenberg SM mBio 35658528 mBio 2022 Jun 28 https://www.ncbi.nlm.nih.gov/pubmed/35658528
Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies. Li Y, Xiao X, Li J, Han Y, Cheng C, Fernandes GF, Slewitzke SE, Rosenberg SM, Zhu M, Byun J, Bossé Y, McKay JD, Albanes D, Lam S, Tardon A, Chen C, Bojesen SE, Landi MT, Johansson M, Risch A, Bickeböller H, Wichmann HE, Christiani DC, Rennert G, Arnold SM, Goodman GE, Field JK, Davies MPA, Shete S, Marchand LL, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Sun R, Zienolddiny S, Grankvist K, Johansson M, Caporaso NE, Cox A, Hong YC, Lazarus P, Schabath MB, Aldrich MC, Schwartz AG, Gorlov I, Purrington KS, Yang P, Liu Y, Bailey-Wilson JE, Pinney SM, Mandal D, Willey JC, Gaba C, Brennan P, Xia J, Shen H, Amos CI Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 38180474 Cancer Epidemiol Biomarkers Prev 2024 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/38180474
Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer's Disease. Fülöp T, Munawara U, Larbi A, Desroches M, Rodrigues S, Catanzaro M, Guidolin A, Khalil A, Bernier F, Barron AE, Hirokawa K, Beauregard PB, Dumoulin D, Bellenger JP, Witkowski JM, Frost E CNS drugs 32458360 CNS Drugs 2020 Jul https://www.ncbi.nlm.nih.gov/pubmed/32458360
Efficacy of Cathelicidin-Mimetic Antimicrobial Peptoids against Staphylococcus aureus. Benjamin AB, Moule MG, Didwania MK, Hardy J, Saenkham-Huntsinger P, Sule P, Nielsen JE, Lin JS, Contag CH, Barron AE, Cirillo JD Microbiology spectrum 35467395 Microbiol Spectr 2022 Jun 29 https://www.ncbi.nlm.nih.gov/pubmed/35467395
Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection. Moule MG, Benjamin AB, Burger ML, Herlan C, Lebedev M, Lin JS, Koster KJ, Wavare N, Adams LG, Bräse S, Munoz-Medina R, Cannon CL, Barron AE, Cirillo JD Communications biology 39174819 Commun Biol 2024 Aug 22 https://www.ncbi.nlm.nih.gov/pubmed/39174819
Acid-degradable lipid nanoparticles enhance the delivery of mRNA. Zhao S, Gao K, Han H, Stenzel M, Yin B, Song H, Lawanprasert A, Nielsen JE, Sharma R, Arogundade OH, Pimcharoen S, Chen YJ, Paul A, Tuma J, Collins MG, Wyle Y, Cranick MG, Burgstone BW, Perez BS, Barron AE, Smith AM, Lee HY, Wang A, Murthy N Nature nanotechnology 39179796 Nat Nanotechnol 2024 Nov https://www.ncbi.nlm.nih.gov/pubmed/39179796
Antiviral Effect of Antimicrobial Peptoid TM9 and Murine Model of Respiratory Coronavirus Infection. Lebedev M, Benjamin AB, Kumar S, Molchanova N, Lin JS, Koster KJ, Leibowitz JL, Barron AE, Cirillo JD Pharmaceutics 38675125 Pharmaceutics 2024 Mar 27 https://www.ncbi.nlm.nih.gov/pubmed/38675125
Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease. Munawara U, Catanzaro M, Xu W, Tan C, Hirokawa K, Bosco N, Dumoulin D, Khalil A, Larbi A, Lévesque S, Ramassamy C, Barron AE, Cunnane S, Beauregard PB, Bellenger JP, Rodrigues S, Desroches M, Witkowski JM, Laurent B, Frost EH, Fulop T Immunity & ageing : I & A 34154615 Immun Ageing 2021 Jun 21 https://www.ncbi.nlm.nih.gov/pubmed/34154615
Supramolecular Peptoid Structure Strengthens Complexation with Polyacrylic Acid Microgels. Zhao W, Lin JS, Nielsen JE, Sørensen K, Wadurkar AS, Ji J, Barron AE, Nangia S, Libera MR Biomacromolecules 38240722 Biomacromolecules 2024 Feb 12 https://www.ncbi.nlm.nih.gov/pubmed/38240722
Antiviral effect of peptoids on hepatitis B virus infection in cell culture. Murayama A, Igarashi H, Yamada N, Aly HH, Molchanova N, Lin JS, Nishitsuji H, Shimotohno K, Muramatsu M, Barron AE, Kato T Antiviral research 38272318 Antiviral Res 2024 Mar https://www.ncbi.nlm.nih.gov/pubmed/38272318
Author Correction: Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection. Moule MG, Benjamin AB, Burger ML, Herlan C, Lebedev M, Lin JS, Koster KJ, Wavare N, Adams LG, Bräse S, Munoz-Medina R, Cannon CL, Barron AE, Cirillo JD Communications biology 39271756 Commun Biol 2024 Sep 13 https://www.ncbi.nlm.nih.gov/pubmed/39271756
Pf bacteriophages hinder sputum antibiotic diffusion via electrostatic binding. Chen Q, Cai P, Chang THW, Burgener E, Kratochvil MJ, Gupta A, Hargil A, Secor PR, Nielsen JE, Barron AE, Milla C, Heilshorn SC, Spakowitz A, Bollyky PL bioRxiv : the preprint server for biology 38496625 bioRxiv 2024 Mar 10 https://www.ncbi.nlm.nih.gov/pubmed/38496625
Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids. Diamond G, Molchanova N, Herlan C, Fortkort JA, Lin JS, Figgins E, Bopp N, Ryan LK, Chung D, Adcock RS, Sherman M, Barron AE Pharmaceuticals (Basel, Switzerland) 33807248 Pharmaceuticals (Basel) 2021 Mar 31 https://www.ncbi.nlm.nih.gov/pubmed/33807248
Membrane-acting biomimetic peptoids against visceral leishmaniasis. Kumar V, Lin JS, Molchanova N, Fortkort JA, Reckmann C, Bräse S, Jenssen H, Barron AE, Chugh A FEBS open bio 36683396 FEBS Open Bio 2023 Mar https://www.ncbi.nlm.nih.gov/pubmed/36683396
Anti-persister and Anti-biofilm Activity of Self-Assembled Antimicrobial Peptoid Ellipsoidal Micelles. Lin JS, Bekale LA, Molchanova N, Nielsen JE, Wright M, Bacacao B, Diamond G, Jenssen H, Santa Maria PL, Barron AE ACS infectious diseases 36018039 ACS Infect Dis 2022 Sep 9 https://www.ncbi.nlm.nih.gov/pubmed/36018039
The anti-inflammatory effects of photobiomodulation are mediated by cytokines: Evidence from a mouse model of inflammation. Shamloo S, Defensor E, Ciari P, Ogawa G, Vidano L, Lin JS, Fortkort JA, Shamloo M, Barron AE Frontiers in neuroscience 37090796 Front Neurosci 2023 https://www.ncbi.nlm.nih.gov/pubmed/37090796
The effect of immobilisation strategies on the ability of peptoids to reduce the adhesion of P. aeruginosa strains to contact lenses. Sara M, Chakraborty S, Chen R, Palms D, Katsifis G, Li Z, Farajikhah S, Massedupally V, Hui A, Wong EHH, Kumar N, Vasilev K, Mackenzie D, Losurdo L, Dehghani F, Jenssen H, Sorensen K, Lin JS, Barron AE, Willcox M Experimental eye research 39571778 Exp Eye Res 2025 Jan https://www.ncbi.nlm.nih.gov/pubmed/39571778
From Global to Nano: A Geographical Perspective of Aggregatibacter actinomycetemcomitans. Ryder MI, Fine DH, Barron AE Pathogens (Basel, Switzerland) 39452709 Pathogens 2024 Sep 27 https://www.ncbi.nlm.nih.gov/pubmed/39452709
The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease. Barron AE, Lin JS, Ryder MI, Bergman P Journal of internal medicine 41424314 J Intern Med 2026 Mar https://www.ncbi.nlm.nih.gov/pubmed/41424314
Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer's Disease. Fulop T, Tripathi S, Rodrigues S, Desroches M, Bunt T, Eiser A, Bernier F, Beauregard PB, Barron AE, Khalil A, Plotka A, Hirokawa K, Larbi A, Bocti C, Laurent B, Frost EH, Witkowski JM Neuropsychiatric disease and treatment 33976546 Neuropsychiatr Dis Treat 2021 https://www.ncbi.nlm.nih.gov/pubmed/33976546
Ethylene oxide graft copolymers reduce the immunogenicity of lipid nanoparticles. Qi Y, Han H, Liu A, Zhao S, Lawanprasert A, Nielsen JE, Choudhary H, Liang D, Barron AE, Murthy N RSC advances 39309654 RSC Adv 2024 Sep 18 https://www.ncbi.nlm.nih.gov/pubmed/39309654
Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens. Nielsen JE, Alford MA, Yung DBY, Molchanova N, Fortkort JA, Lin JS, Diamond G, Hancock REW, Jenssen H, Pletzer D, Lund R, Barron AE ACS infectious diseases 35175731 ACS Infect Dis 2022 Mar 11 https://www.ncbi.nlm.nih.gov/pubmed/35175731
Real-Time Monitoring of Multitarget Antimicrobial Mechanisms of Peptoids Using Label-Free Imaging with Optical Diffraction Tomography. Kim M, Cheon Y, Shin D, Choi J, Nielsen JE, Jeong MS, Nam HY, Kim SH, Lund R, Jenssen H, Barron AE, Lee S, Seo J Advanced science (Weinheim, Baden-Wurttemberg, Germany) 37341246 Adv Sci (Weinh) 2023 Aug https://www.ncbi.nlm.nih.gov/pubmed/37341246
The activity of antimicrobial peptoids against multidrug-resistant ocular pathogens. Sara M, Yasir M, Kalaiselvan P, Hui A, Kuppusamy R, Kumar N, Chakraborty S, Yu TT, Wong EHH, Molchanova N, Jenssen H, Lin JS, Barron AE, Willcox M Contact lens & anterior eye : the journal of the British Contact Lens Association 38341309 Cont Lens Anterior Eye 2024 Apr https://www.ncbi.nlm.nih.gov/pubmed/38341309
Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasis. Park S, Matte-Martone C, Gonzalez DG, Lathrop EA, May DP, Pineda CM, Moore JL, Boucher JD, Marsh E, Schmitter-Sánchez A, Cockburn K, Markova O, Bellaïche Y, Greco V Nature cell biology 33958758 Nat Cell Biol 2021 May https://www.ncbi.nlm.nih.gov/pubmed/33958758
Cell cycle controls long-range calcium signaling in the regenerating epidermis. Moore JL, Bhaskar D, Gao F, Matte-Martone C, Du S, Lathrop E, Ganesan S, Shao L, Norris R, Campamà Sanz N, Annusver K, Kasper M, Cox A, Hendry C, Rieck B, Krishnaswamy S, Greco V The Journal of cell biology 37102999 J Cell Biol 2023 Jul 3 https://www.ncbi.nlm.nih.gov/pubmed/37102999
Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo. May D, Yun S, Gonzalez DG, Park S, Chen Y, Lathrop E, Cai B, Xin T, Zhao H, Wang S, Gonzalez LE, Cockburn K, Greco V eLife 36880644 Elife 2023 Mar 7 https://www.ncbi.nlm.nih.gov/pubmed/36880644
Organ function is preserved despite reorganization of niche architecture in the hair follicle. Wei H, Du S, Parksong J, Pasolli HA, Matte-Martone C, Regot S, Gonzalez LE, Xin T, Greco V Cell stem cell 37419106 Cell Stem Cell 2023 Jul 6 https://www.ncbi.nlm.nih.gov/pubmed/37419106
Selective utilization of glucose metabolism guides mammalian gastrulation. Cao D, Bergmann J, Zhong L, Hemalatha A, Dingare C, Jensen T, Cox AL, Greco V, Steventon B, Sozen B Nature 39415005 Nature 2024 Oct https://www.ncbi.nlm.nih.gov/pubmed/39415005
Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice. Kam CY, Singh ID, Gonzalez DG, Matte-Martone C, Solá P, Solanas G, Bonjoch J, Marsh E, Hirschi KK, Greco V Cell 37167971 Cell 2023 May 25 https://www.ncbi.nlm.nih.gov/pubmed/37167971
A Spatiotemporal Compartmentalization of Glucose Metabolism Guides Mammalian Gastrulation Progression. Cao D, Zhong L, Hemalatha A, Bergmann J, Cox AL, Greco V, Sozen B bioRxiv : the preprint server for biology 37333168 bioRxiv 2023 Jun 8 https://www.ncbi.nlm.nih.gov/pubmed/37333168
The art of observation: bridging science and art to see the unexpected. Gonzalez LE, Wei H, Greco V, Friedlaender LK Development (Cambridge, England) 38477686 Development 2024 Mar 1 https://www.ncbi.nlm.nih.gov/pubmed/38477686
Probing the rules of cell coordination in live tissues by interpretable machine learning based on graph neural networks. Yamamoto T, Cockburn K, Greco V, Kawaguchi K PLoS computational biology 36067226 PLoS Comput Biol 2022 Sep https://www.ncbi.nlm.nih.gov/pubmed/36067226
Functional cell death, corneoptosis, requires temporally controlled intracellular acidification. Moore JL, Greco V Proceedings of the National Academy of Sciences of the United States of America 33986147 Proc Natl Acad Sci U S A 2021 Jun 1 https://www.ncbi.nlm.nih.gov/pubmed/33986147
Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer. Cockburn K, Annusver K, Gonzalez DG, Ganesan S, May DP, Mesa KR, Kawaguchi K, Kasper M, Greco V Nature cell biology 36357619 Nat Cell Biol 2022 Dec https://www.ncbi.nlm.nih.gov/pubmed/36357619
Injury prevents Ras mutant cell expansion in mosaic skin. Gallini S, Annusver K, Rahman NT, Gonzalez DG, Yun S, Matte-Martone C, Xin T, Lathrop E, Suozzi KC, Kasper M, Greco V Nature 37344586 Nature 2023 Jul https://www.ncbi.nlm.nih.gov/pubmed/37344586
Metabolic rewiring in skin epidermis drives tolerance to oncogenic mutations. Hemalatha A, Li Z, Gonzalez DG, Matte-Martone C, Tai K, Lathrop E, Gil D, Ganesan S, Gonzalez LE, Skala M, Perry RJ, Greco V Nature cell biology 39762578 Nat Cell Biol 2025 Feb https://www.ncbi.nlm.nih.gov/pubmed/39762578
Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation. Xin T, Gallini S, Wei H, Gonzalez DG, Matte-Martone C, Machida H, Fujiwara H, Pasolli HA, Suozzi KC, Gonzalez LE, Regot S, Greco V Nature cell biology 38689013 Nat Cell Biol 2024 Jun https://www.ncbi.nlm.nih.gov/pubmed/38689013
From start to finish-a molecular link in wound repair. Yun S, Greco V Science (New York, N.Y.) 35143296 Science 2022 Feb 11 https://www.ncbi.nlm.nih.gov/pubmed/35143296
Fibroblast depletion reveals mammalian epithelial resilience across neonatal and adult stages. Gaeta IM, Du S, Villeneuve C, Gonzalez DG, Matte-Martone C, Ganesan S, Simpson D, Moore JL, Kam CY, Gallini S, Wei H, Bertillot F, Zeuschner D, Gonzalez LE, Sumigray KD, Wickström SA, Greco V bioRxiv : the preprint server for biology 40766486 bioRxiv 2025 Jul 31 https://www.ncbi.nlm.nih.gov/pubmed/40766486
Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species. Tabebordbar M, Lagerborg KA, Stanton A, King EM, Ye S, Tellez L, Krunnfusz A, Tavakoli S, Widrick JJ, Messemer KA, Troiano EC, Moghadaszadeh B, Peacker BL, Leacock KA, Horwitz N, Beggs AH, Wagers AJ, Sabeti PC Cell 34506722 Cell 2021 Sep 16 https://www.ncbi.nlm.nih.gov/pubmed/34506722
In Situ Modification of Tissue Stem and Progenitor Cell Genomes. Goldstein JM, Tabebordbar M, Zhu K, Wang LD, Messemer KA, Peacker B, Ashrafi Kakhki S, Gonzalez-Celeiro M, Shwartz Y, Cheng JKW, Xiao R, Barungi T, Albright C, Hsu YC, Vandenberghe LH, Wagers AJ Cell reports 31018138 Cell Rep 2019 Apr 23 https://www.ncbi.nlm.nih.gov/pubmed/31018138
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells. Yagi M, Ji F, Charlton J, Cristea S, Messemer K, Horwitz N, Di Stefano B, Tsopoulidis N, Hoetker MS, Huebner AJ, Bar-Nur O, Almada AE, Yamamoto M, Patelunas A, Goldhamer DJ, Wagers AJ, Michor F, Meissner A, Sadreyev RI, Hochedlinger K Genes & development 34413137 Genes Dev 2021 Sep 1 https://www.ncbi.nlm.nih.gov/pubmed/34413137
High-efficiency purification of divergent AAV serotypes using AAVX affinity chromatography. Florea M, Nicolaou F, Pacouret S, Zinn EM, Sanmiguel J, Andres-Mateos E, Unzu C, Wagers AJ, Vandenberghe LH Molecular therapy. Methods & clinical development 36654797 Mol Ther Methods Clin Dev 2023 Mar 9 https://www.ncbi.nlm.nih.gov/pubmed/36654797
Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer-based precipitation and size exclusion chromatography. Martínez-Greene JA, Hernández-Ortega K, Quiroz-Baez R, Resendis-Antonio O, Pichardo-Casas I, Sinclair DA, Budnik B, Hidalgo-Miranda A, Uribe-Querol E, Ramos-Godínez MDP, Martínez-Martínez E Journal of extracellular vesicles 33936570 J Extracell Vesicles 2021 Apr https://www.ncbi.nlm.nih.gov/pubmed/33936570
Multiple basal cell carcinomas in a patient with myotonic dystrophy type 1. Feng J, LaChance A, Sinclair DA, Asgari MM BMJ case reports 30852496 BMJ Case Rep 2019 Mar 8 https://www.ncbi.nlm.nih.gov/pubmed/30852496
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Tarantini S, Valcarcel-Ares MN, Toth P, Yabluchanskiy A, Tucsek Z, Kiss T, Hertelendy P, Kinter M, Ballabh P, Süle Z, Farkas E, Baur JA, Sinclair DA, Csiszar A, Ungvari Z Redox biology 31015147 Redox Biol 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31015147
Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice. Ross JM, Coppotelli G, Branca RM, Kim KM, Lehtiö J, Sinclair DA, Olson L Aging cell 31489782 Aging Cell 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31489782
Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research. Montano M, Bhasin S, D'Aquila RT, Erlandson KM, Evans WJ, Funderburg NT, Justice A, Ndhlovu LC, Ojikutu B, Pahor M, Pahwa S, Ryan AS, Schrack J, Schultz MB, Sebastiani P, Sinclair DA, Tripp J, Walker B, Womack JA, Yung R, Reeves RK AIDS research and human retroviruses 31456412 AIDS Res Hum Retroviruses 2019 Nov-Dec https://www.ncbi.nlm.nih.gov/pubmed/31456412
NAD(+) in Brain Aging and Neurodegenerative Disorders. Lautrup S, Sinclair DA, Mattson MP, Fang EF Cell metabolism 31577933 Cell Metab 2019 Oct 1 https://www.ncbi.nlm.nih.gov/pubmed/31577933
Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage. Bolderson E, Burgess JT, Li J, Gandhi NS, Boucher D, Croft LV, Beard S, Plowman JJ, Suraweera A, Adams MN, Naqi A, Zhang SD, Sinclair DA, O'Byrne KJ, Richard DJ Nature communications 31796734 Nat Commun 2019 Dec 3 https://www.ncbi.nlm.nih.gov/pubmed/31796734
Frailty biomarkers in humans and rodents: Current approaches and future advances. Kane AE, Sinclair DA Mechanisms of ageing and development 31002925 Mech Ageing Dev 2019 Jun https://www.ncbi.nlm.nih.gov/pubmed/31002925
Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice. Youngson NA, Uddin GM, Das A, Martinez C, Connaughton HS, Whiting S, Yu J, Sinclair DA, Aitken RJ, Morris MJ Reproduction (Cambridge, England) 31226694 Reproduction 2019 Aug 1 https://www.ncbi.nlm.nih.gov/pubmed/31226694
Impairment of an Endothelial NAD(+)-H(2)S Signaling Network Is a Reversible Cause of Vascular Aging. Das A, Huang GX, Bonkowski MS, Longchamp A, Li C, Schultz MB, Kim LJ, Osborne B, Joshi S, Lu Y, Treviño-Villarreal JH, Kang MJ, Hung TT, Lee B, Williams EO, Igarashi M, Mitchell JR, Wu LE, Turner N, Arany Z, Guarente L, Sinclair DA Cell 29570999 Cell 2018 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/29570999
Epigenetic changes during aging and their reprogramming potential. Kane AE, Sinclair DA Critical reviews in biochemistry and molecular biology 30822165 Crit Rev Biochem Mol Biol 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30822165
Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions. Latorre-Muro P, Baeza J, Armstrong EA, Hurtado-Guerrero R, Corzana F, Wu LE, Sinclair DA, López-Buesa P, Carrodeguas JA, Denu JM Molecular cell 30193097 Mol Cell 2018 Sep 6 https://www.ncbi.nlm.nih.gov/pubmed/30193097
Sirtuins and NAD(+) in the Development and Treatment of Metabolic and Cardiovascular Diseases. Kane AE, Sinclair DA Circulation research 30355082 Circ Res 2018 Sep 14 https://www.ncbi.nlm.nih.gov/pubmed/30355082
Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins. Palmeira CM, Teodoro JS, Amorim JA, Steegborn C, Sinclair DA, Rolo AP Free radical biology & medicine 31349039 Free Radic Biol Med 2019 Sep https://www.ncbi.nlm.nih.gov/pubmed/31349039
Molecular and Cellular Characterization of SIRT1 Allosteric Activators. Schultz MB, Rinaldi C, Lu Y, Amorim JA, Sinclair DA Methods in molecular biology (Clifton, N.J.) 31087296 Methods Mol Biol 2019 https://www.ncbi.nlm.nih.gov/pubmed/31087296
Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults. Pollack RM, Barzilai N, Anghel V, Kulkarni AS, Golden A, O'Broin P, Sinclair DA, Bonkowski MS, Coleville AJ, Powell D, Kim S, Moaddel R, Stein D, Zhang K, Hawkins M, Crandall JP The journals of gerontology. Series A, Biological sciences and medical sciences 28329397 J Gerontol A Biol Sci Med Sci 2017 Nov 9 https://www.ncbi.nlm.nih.gov/pubmed/28329397
Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide. Bertoldo MJ, Uddin GM, Youngson NA, Agapiou D, Walters KA, Sinclair DA, Morris MJ, Gilchrist RB Human reproduction open 30895251 Hum Reprod Open 2018 https://www.ncbi.nlm.nih.gov/pubmed/30895251
Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice. Wahl D, Solon-Biet SM, Wang QP, Wali JA, Pulpitel T, Clark X, Raubenheimer D, Senior AM, Sinclair DA, Cooney GJ, de Cabo R, Cogger VC, Simpson SJ, Le Couteur DG Cell reports 30463018 Cell Rep 2018 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/30463018
Publisher Correction: Longitudinal analysis of biomarker data from a personalized nutrition platform in healthy subjects. Westerman K, Reaver A, Roy C, Ploch M, Sharoni E, Nogal B, Sinclair DA, Katz DL, Blumberg JB, Blander G Scientific reports 30405144 Sci Rep 2018 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/30405144
Assays for NAD(+)-Dependent Reactions and NAD(+) Metabolites. Schultz MB, Lu Y, Braidy N, Sinclair DA Methods in molecular biology (Clifton, N.J.) 30097862 Methods Mol Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/30097862
Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles. Bonora M, Wieckowski MR, Sinclair DA, Kroemer G, Pinton P, Galluzzi L Nature reviews. Cardiology 30177752 Nat Rev Cardiol 2019 Jan https://www.ncbi.nlm.nih.gov/pubmed/30177752
Longitudinal analysis of biomarker data from a personalized nutrition platform in healthy subjects. Westerman K, Reaver A, Roy C, Ploch M, Sharoni E, Nogal B, Sinclair DA, Katz DL, Blumberg JB, Blander G Scientific reports 30279436 Sci Rep 2018 Oct 2 https://www.ncbi.nlm.nih.gov/pubmed/30279436
Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H(2)S Production. Longchamp A, Mirabella T, Arduini A, MacArthur MR, Das A, Treviño-Villarreal JH, Hine C, Ben-Sahra I, Knudsen NH, Brace LE, Reynolds J, Mejia P, Tao M, Sharma G, Wang R, Corpataux JM, Haefliger JA, Ahn KH, Lee CH, Manning BD, Sinclair DA, Chen CS, Ozaki CK, Mitchell JR Cell 29570992 Cell 2018 Mar 22 https://www.ncbi.nlm.nih.gov/pubmed/29570992
Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise. Uddin GM, Youngson NA, Doyle BM, Sinclair DA, Morris MJ Scientific reports 29118320 Sci Rep 2017 Nov 8 https://www.ncbi.nlm.nih.gov/pubmed/29118320
Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance. Costford SR, Brouwers B, Hopf ME, Sparks LM, Dispagna M, Gomes AP, Cornnell HH, Petucci C, Phelan P, Xie H, Yi F, Walter GA, Osborne TF, Sinclair DA, Mynatt RL, Ayala JE, Gardell SJ, Smith SR Molecular metabolism 29146412 Mol Metab 2018 Jan https://www.ncbi.nlm.nih.gov/pubmed/29146412
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Papain-based Single Cell Isolation of Primary Murine Brain Endothelial Cells Using Flow Cytometry. Yousef H, Czupalla CJ, Lee D, Butcher EC, Wyss-Coray T Bio-protocol 31032379 Bio Protoc 2018 Nov 20 https://www.ncbi.nlm.nih.gov/pubmed/31032379
Undulating changes in human plasma proteome profiles across the lifespan. Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T Nature medicine 31806903 Nat Med 2019 Dec https://www.ncbi.nlm.nih.gov/pubmed/31806903
Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway. Bang J, Jang M, Huh JH, Na JW, Shim M, Carlson BA, Tobe R, Tsuji PA, Gladyshev VN, Hatfield DL, Lee BJ Biochemical and biophysical research communications 25529450 Biochem Biophys Res Commun 2015 Jan 24 https://www.ncbi.nlm.nih.gov/pubmed/25529450
INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform. Tian X, Azpurua J, Ke Z, Augereau A, Zhang ZD, Vijg J, Gladyshev VN, Gorbunova V, Seluanov A Proceedings of the National Academy of Sciences of the United States of America 25550505 Proc Natl Acad Sci U S A 2015 Jan 27 https://www.ncbi.nlm.nih.gov/pubmed/25550505
Gene expression defines natural changes in mammalian lifespan. Fushan AA, Turanov AA, Lee SG, Kim EB, Lobanov AV, Yim SH, Buffenstein R, Lee SR, Chang KT, Rhee H, Kim JS, Yang KS, Gladyshev VN Aging cell 25677554 Aging Cell 2015 Jun https://www.ncbi.nlm.nih.gov/pubmed/25677554
Convergent evolution of marine mammals is associated with distinct substitutions in common genes. Zhou X, Seim I, Gladyshev VN Scientific reports 26549748 Sci Rep 2015 Nov 9 https://www.ncbi.nlm.nih.gov/pubmed/26549748
Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes. Gladyshev VN Aging cell 27060562 Aging Cell 2016 Aug https://www.ncbi.nlm.nih.gov/pubmed/27060562
Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells. Ogrodnik M, Salmonowicz H, Gladyshev VN Aging cell 30346102 Aging Cell 2019 Feb https://www.ncbi.nlm.nih.gov/pubmed/30346102
Multifaceted deregulation of gene expression and protein synthesis with age. Anisimova AS, Meerson MB, Gerashchenko MV, Kulakovskiy IV, Dmitriev SE, Gladyshev VN Proceedings of the National Academy of Sciences of the United States of America 32576685 Proc Natl Acad Sci U S A 2020 Jul 7 https://www.ncbi.nlm.nih.gov/pubmed/32576685
Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity. Zhou X, Dou Q, Fan G, Zhang Q, Sanderford M, Kaya A, Johnson J, Karlsson EK, Tian X, Mikhalchenko A, Kumar S, Seluanov A, Zhang ZD, Gorbunova V, Liu X, Gladyshev VN Cell reports 32726638 Cell Rep 2020 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/32726638
Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration. Carlson BA, Tobe R, Yefremova E, Tsuji PA, Hoffmann VJ, Schweizer U, Gladyshev VN, Hatfield DL, Conrad M Redox biology 27262435 Redox Biol 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27262435
A Disease or Not a Disease? Aging As a Pathology. Gladyshev TV, Gladyshev VN Trends in molecular medicine 27793599 Trends Mol Med 2016 Dec https://www.ncbi.nlm.nih.gov/pubmed/27793599
Gene expression signatures of human cell and tissue longevity. Seim I, Ma S, Gladyshev VN NPJ aging and mechanisms of disease 28721269 NPJ Aging Mech Dis 2016 https://www.ncbi.nlm.nih.gov/pubmed/28721269
Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions. Petkovich DA, Podolskiy DI, Lobanov AV, Lee SG, Miller RA, Gladyshev VN Cell metabolism 28380383 Cell Metab 2017 Apr 4 https://www.ncbi.nlm.nih.gov/pubmed/28380383
The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal. Seim I, Ma S, Zhou X, Gerashchenko MV, Lee SG, Suydam R, George JC, Bickham JW, Gladyshev VN Aging 25411232 Aging (Albany NY) 2014 Oct https://www.ncbi.nlm.nih.gov/pubmed/25411232
Translation fidelity coevolves with longevity. Ke Z, Mallik P, Johnson AB, Luna F, Nevo E, Zhang ZD, Gladyshev VN, Seluanov A, Gorbunova V Aging cell 28707419 Aging Cell 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28707419
Non-enzymatic molecular damage as a prototypic driver of aging. Golubev A, Hanson AD, Gladyshev VN The Journal of biological chemistry 28264930 J Biol Chem 2017 Apr 14 https://www.ncbi.nlm.nih.gov/pubmed/28264930
Analysis of cancer genomes reveals basic features of human aging and its role in cancer development. Podolskiy DI, Lobanov AV, Kryukov GV, Gladyshev VN Nature communications 27515585 Nat Commun 2016 Aug 12 https://www.ncbi.nlm.nih.gov/pubmed/27515585
Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes. Fang X, Seim I, Huang Z, Gerashchenko MV, Xiong Z, Turanov AA, Zhu Y, Lobanov AV, Fan D, Yim SH, Yao X, Ma S, Yang L, Lee SG, Kim EB, Bronson RT, Šumbera R, Buffenstein R, Zhou X, Krogh A, Park TJ, Zhang G, Wang J, Gladyshev VN Cell reports 25176646 Cell Rep 2014 Sep 11 https://www.ncbi.nlm.nih.gov/pubmed/25176646
Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction. Sziráki A, Tyshkovskiy A, Gladyshev VN Aging cell 29575528 Aging Cell 2018 Jun https://www.ncbi.nlm.nih.gov/pubmed/29575528
Extrarenal expression of α-klotho, the kidney related longevity gene, in Heterocephalus glaber, the long living Naked Mole Rat. Morevati M, Mace ML, Egstrand S, Nordholm A, Doganli C, Strand J, Rukov JL, Torsetnes SB, Gorbunova V, Olgaard K, Lewin E Scientific reports 34321565 Sci Rep 2021 Jul 28 https://www.ncbi.nlm.nih.gov/pubmed/34321565
Biological age is increased by stress and restored upon recovery. Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN Cell metabolism 37086720 Cell Metab 2023 May 2 https://www.ncbi.nlm.nih.gov/pubmed/37086720
Comparative genetics of longevity and cancer: insights from long-lived rodents. Gorbunova V, Seluanov A, Zhang Z, Gladyshev VN, Vijg J Nature reviews. Genetics 24981598 Nat Rev Genet 2014 Aug https://www.ncbi.nlm.nih.gov/pubmed/24981598
Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity. Ma S, Lee SG, Kim EB, Park TJ, Seluanov A, Gorbunova V, Buffenstein R, Seravalli J, Gladyshev VN Cell reports 26549444 Cell Rep 2015 Nov 17 https://www.ncbi.nlm.nih.gov/pubmed/26549444
Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity. Ma S, Yim SH, Lee SG, Kim EB, Lee SR, Chang KT, Buffenstein R, Lewis KN, Park TJ, Miller RA, Clish CB, Gladyshev VN Cell metabolism 26244935 Cell Metab 2015 Aug 4 https://www.ncbi.nlm.nih.gov/pubmed/26244935
Molecular signatures of longevity: Insights from cross-species comparative studies. Ma S, Gladyshev VN Seminars in cell & developmental biology 28800931 Semin Cell Dev Biol 2017 Oct https://www.ncbi.nlm.nih.gov/pubmed/28800931
Germline burden of rare damaging variants negatively affects human healthspan and lifespan. Shindyapina AV, Zenin AA, Tarkhov AE, Santesmasses D, Fedichev PO, Gladyshev VN eLife 32254024 Elife 2020 Apr 7 https://www.ncbi.nlm.nih.gov/pubmed/32254024
Systematic age-, organ-, and diet-associated ionome remodeling and the development of ionomic aging clocks. Zhang B, Podolskiy DI, Mariotti M, Seravalli J, Gladyshev VN Aging cell 32323920 Aging Cell 2020 May https://www.ncbi.nlm.nih.gov/pubmed/32323920
DNA methylation aging clocks: challenges and recommendations. Bell CG, Lowe R, Adams PD, Baccarelli AA, Beck S, Bell JT, Christensen BC, Gladyshev VN, Heijmans BT, Horvath S, Ideker T, Issa JJ, Kelsey KT, Marioni RE, Reik W, Relton CL, Schalkwyk LC, Teschendorff AE, Wagner W, Zhang K, Rakyan VK Genome biology 31767039 Genome Biol 2019 Nov 25 https://www.ncbi.nlm.nih.gov/pubmed/31767039
SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, Yang JN, Mao Z, Manta B, Dang W, Zhang Z, Vijg J, Wolfe A, Moody K, Kennedy BK, Bohmann D, Gladyshev VN, Seluanov A, Gorbunova V Cell 31002797 Cell 2019 Apr 18 https://www.ncbi.nlm.nih.gov/pubmed/31002797
Naked Mole Rat Induced Pluripotent Stem Cells and Their Contribution to Interspecific Chimera. Lee SG, Mikhalchenko AE, Yim SH, Lobanov AV, Park JK, Choi KH, Bronson RT, Lee CK, Park TJ, Gladyshev VN Stem cell reports 29107591 Stem Cell Reports 2017 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/29107591
Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human. MacRae SL, Zhang Q, Lemetre C, Seim I, Calder RB, Hoeijmakers J, Suh Y, Gladyshev VN, Seluanov A, Gorbunova V, Vijg J, Zhang ZD Aging cell 25645816 Aging Cell 2015 Apr https://www.ncbi.nlm.nih.gov/pubmed/25645816
Selenocysteine tRNA([Ser]Sec), the Central Component of Selenoprotein Biosynthesis: Isolation, Identification, Modification, and Sequencing. Carlson BA, Lee BJ, Tsuji PA, Copeland PR, Schweizer U, Gladyshev VN, Hatfield DL Methods in molecular biology (Clifton, N.J.) 28917036 Methods Mol Biol 2018 https://www.ncbi.nlm.nih.gov/pubmed/28917036
Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates. Kaya A, Ma S, Wasko B, Lee M, Kaeberlein M, Gladyshev VN NPJ aging and mechanisms of disease 27030810 NPJ Aging Mech Dis 2015 https://www.ncbi.nlm.nih.gov/pubmed/27030810
Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. Ma S, Upneja A, Galecki A, Tsai YM, Burant CF, Raskind S, Zhang Q, Zhang ZD, Seluanov A, Gorbunova V, Clish CB, Miller RA, Gladyshev VN eLife 27874830 Elife 2016 Nov 22 https://www.ncbi.nlm.nih.gov/pubmed/27874830
Intrinsic Versus Extrinsic Cancer Risk Factors and Aging. Podolskiy DI, Gladyshev VN Trends in molecular medicine 27544777 Trends Mol Med 2016 Oct https://www.ncbi.nlm.nih.gov/pubmed/27544777
Age-associated molecular changes are deleterious and may modulate life span through diet. Lee SG, Kaya A, Avanesov AS, Podolskiy DI, Song EJ, Go DM, Jin GD, Hwang JY, Kim EB, Kim DY, Gladyshev VN Science advances 28232953 Sci Adv 2017 Feb https://www.ncbi.nlm.nih.gov/pubmed/28232953
Mechanisms of cancer resistance in long-lived mammals. Seluanov A, Gladyshev VN, Vijg J, Gorbunova V Nature reviews. Cancer 29622806 Nat Rev Cancer 2018 Jul https://www.ncbi.nlm.nih.gov/pubmed/29622806
Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity. Ma S, Avanesov AS, Porter E, Lee BC, Mariotti M, Zemskaya N, Guigo R, Moskalev AA, Gladyshev VN Aging cell 29671950 Aging Cell 2018 Aug https://www.ncbi.nlm.nih.gov/pubmed/29671950
Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence. Zhao Y, Tyshkovskiy A, Muñoz-Espín D, Tian X, Serrano M, de Magalhaes JP, Nevo E, Gladyshev VN, Seluanov A, Gorbunova V Proceedings of the National Academy of Sciences of the United States of America 29432174 Proc Natl Acad Sci U S A 2018 Feb 20 https://www.ncbi.nlm.nih.gov/pubmed/29432174
A whole lifespan mouse multi-tissue DNA methylation clock. Meer MV, Podolskiy DI, Tyshkovskiy A, Gladyshev VN eLife 30427307 Elife 2018 Nov 14 https://www.ncbi.nlm.nih.gov/pubmed/30427307
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation. Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, De Cecco M, Leonova KI, Kogan V, Helfand SL, Neretti N, Roichman A, Cohen HY, Meer MV, Gladyshev VN, Antoch MP, Gudkov AV, Sedivy JM, Seluanov A, Gorbunova V Cell metabolism 30853213 Cell Metab 2019 Apr 2 https://www.ncbi.nlm.nih.gov/pubmed/30853213
Identification and Application of Gene Expression Signatures Associated with Lifespan Extension. Tyshkovskiy A, Bozaykut P, Borodinova AA, Gerashchenko MV, Ables GP, Garratt M, Khaitovich P, Clish CB, Miller RA, Gladyshev VN Cell metabolism 31353263 Cell Metab 2019 Sep 3 https://www.ncbi.nlm.nih.gov/pubmed/31353263
The Effects of Stress Exposure on Prefrontal Cortex: Translating Basic Research into Successful Treatments for Post-Traumatic Stress Disorder. Arnsten AF, Raskind MA, Taylor FB, Connor DF Neurobiology of stress 25436222 Neurobiol Stress 2015 Jan 1 https://www.ncbi.nlm.nih.gov/pubmed/25436222
Dopamine's Actions in Primate Prefrontal Cortex: Challenges for Treating Cognitive Disorders. Arnsten AF, Wang M, Paspalas CD Pharmacological reviews 26106146 Pharmacol Rev 2015 Jul https://www.ncbi.nlm.nih.gov/pubmed/26106146
Ketamine's Antidepressant Actions: Potential Mechanisms in the Primate Medial Prefrontal Circuits That Represent Aversive Experience. Arnsten AF, Murray JD, Seo H, Lee D Biological psychiatry 27079495 Biol Psychiatry 2016 May 1 https://www.ncbi.nlm.nih.gov/pubmed/27079495
Age-related calcium dysregulation linked with tau pathology and impaired cognition in non-human primates. Datta D, Leslie SN, Wang M, Morozov YM, Yang S, Mentone S, Zeiss C, Duque A, Rakic P, Horvath TL, van Dyck CH, Nairn AC, Arnsten AFT Alzheimer's & dementia : the journal of the Alzheimer's Association 33829643 Alzheimers Dement 2021 Jun https://www.ncbi.nlm.nih.gov/pubmed/33829643
The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development. Tebbenkamp ATN, Varela L, Choi J, Paredes MI, Giani AM, Song JE, Sestan-Pesa M, Franjic D, Sousa AMM, Liu ZW, Li M, Bichsel C, Koch M, Szigeti-Buck K, Liu F, Li Z, Kawasawa YI, Paspalas CD, Mineur YS, Prontera P, Merla G, Picciotto MR, Arnsten AFT, Horvath TL, Sestan N Cell 30318146 Cell 2018 Nov 1 https://www.ncbi.nlm.nih.gov/pubmed/30318146
A novel dopamine D1 receptor agonist excites delay-dependent working memory-related neuronal firing in primate dorsolateral prefrontal cortex. Wang M, Datta D, Enwright J, Galvin V, Yang ST, Paspalas C, Kozak R, Gray DL, Lewis DA, Arnsten AFT Neuropharmacology 30858103 Neuropharmacology 2019 May 15 https://www.ncbi.nlm.nih.gov/pubmed/30858103
Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability and Working Memory. Wu J, El-Hassar L, Datta D, Thomas M, Zhang Y, Jenkins DP, DeLuca NJ, Chatterjee M, Gribkoff VK, Arnsten AFT, Kaczmarek LK Research square 37205397 Res Sq 2023 May 4 https://www.ncbi.nlm.nih.gov/pubmed/37205397
Ameliorating treatment-refractory depression with intranasal ketamine: potential NMDA receptor actions in the pain circuitry representing mental anguish. Opler LA, Opler MG, Arnsten AF CNS spectrums 25619798 CNS Spectr 2016 Feb https://www.ncbi.nlm.nih.gov/pubmed/25619798
Targeting Prefrontal Cortical Systems for Drug Development: Potential Therapies for Cognitive Disorders. Arnsten AF, Wang M Annual review of pharmacology and toxicology 26738476 Annu Rev Pharmacol Toxicol 2016 https://www.ncbi.nlm.nih.gov/pubmed/26738476
The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology. Paspalas CD, Carlyle BC, Leslie S, Preuss TM, Crimins JL, Huttner AJ, van Dyck CH, Rosene DL, Nairn AC, Arnsten AFT Alzheimer's & dementia : the journal of the Alzheimer's Association 29241829 Alzheimers Dement 2018 May https://www.ncbi.nlm.nih.gov/pubmed/29241829
Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia. Datta D, Arnsten AFT ACS chemical neuroscience 29470055 ACS Chem Neurosci 2018 Sep 19 https://www.ncbi.nlm.nih.gov/pubmed/29470055
Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease. Arnsten AFT, Datta D, Del Tredici K, Braak H Alzheimer's & dementia : the journal of the Alzheimer's Association 33075193 Alzheimers Dement 2021 Jan https://www.ncbi.nlm.nih.gov/pubmed/33075193
Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex. Datta D, Leslie SN, Morozov YM, Duque A, Rakic P, van Dyck CH, Nairn AC, Arnsten AFT Journal of neuroinflammation 31906973 J Neuroinflammation 2020 Jan 6 https://www.ncbi.nlm.nih.gov/pubmed/31906973
Studies of aging nonhuman primates illuminate the etiology of early-stage Alzheimer's-like neuropathology: An evolutionary perspective. Arnsten AFT, Datta D, Preuss TM American journal of primatology 33960505 Am J Primatol 2021 Nov https://www.ncbi.nlm.nih.gov/pubmed/33960505
Phosphodiesterase PDE4D Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau. Leslie SN, Datta D, Christensen KR, van Dyck CH, Arnsten AFT, Nairn AC Frontiers in aging neuroscience 33192469 Front Aging Neurosci 2020 https://www.ncbi.nlm.nih.gov/pubmed/33192469
Noradrenergic α1-Adrenoceptor Actions in the Primate Dorsolateral Prefrontal Cortex. Datta D, Yang ST, Galvin VC, Solder J, Luo F, Morozov YM, Arellano J, Duque A, Rakic P, Arnsten AFT, Wang M The Journal of neuroscience : the official journal of the Society for Neuroscience 30755491 J Neurosci 2019 Apr 3 https://www.ncbi.nlm.nih.gov/pubmed/30755491
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