Epigenomics
Epigenomics
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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
| Title | Authors | Journal | PubMedID | Publication Date |
|---|---|---|---|---|
| Race/ethnicity, gender, and monitoring socioeconomic gradients in health: a comparison of area-based socioeconomic measures--the public health disparities geocoding project. | Krieger, Nancy; Chen, Jarvis T; Waterman, Pamela D; Rehkopf, David H; Subramanian, S V | American journal of public health. | 14534218 | 2003 Oct; |
| Painting a truer picture of US socioeconomic and racial/ethnic health inequalities: the Public Health Disparities Geocoding Project. | Krieger, Nancy; Chen, Jarvis T; Waterman, Pamela D; Rehkopf, David H; Subramanian, S V | American journal of public health | 15671470 | 2005 Feb |
| Lysine propionylation and butyrylation are novel post-translational modifications in histones. | Chen, Yue; Sprung, Robert; Tang, Yi; Ball, Haydn; Sangras, Bhavani; Kim, Sung Chan; Falck, John R; Peng, Junmin; Gu, Wei; Zhao, Yingming | Molecular & cellular proteomics : MCP | 17267393 | 2007 May |
| Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer's disease. | Lee, Joseph H; Barral, Sandra; Cheng, Rong; Chacon, Inara; Santana, Vincent; Williamson, Jennifer; Lantigua, Rafael; Medrano, Martin; Jimenez-Velazquez, Ivonne Z; Stern, Yaakov; Tycko, Benjamin; Rogaeva, Ekaterina; Wakutani, Yosuke; Kawarai, Toshitaka; St George-Hyslop, Peter; Mayeux, Richard | Neurogenetics. | 17940814 | 2008 Feb; |
| Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective. | Jarboe, E A; Folkins, A K; Drapkin, R; Ince, T A; Agoston, E S; Crum, C P | Histopathology | 18298580 | 2008 Aug |
| Changes in the distributions and dynamics of polycomb repressive complexes during embryonic stem cell differentiation. | Ren, Xiaojun; Vincenz, Claudius; Kerppola, Tom K | Molecular and cellular biology | 18316406 | 2008 May |
| Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. | Mill, Jonathan; Tang, Thomas; Kaminsky, Zachary; Khare, Tarang; Yazdanpanah, Simin; Bouchard, Luigi; Jia, Peixin; Assadzadeh, Abbas; Flanagan, James; Schumacher, Axel; Wang, Sun-Chong; Petronis, Arturas | American journal of human genetics | 18319075 | 2008 Mar |
| The role of osteopontin in the development of albuminuria. | Lorenzen, Johan; Shah, Rajshree; Biser, Alisha; Staicu, Serban A; Niranjan, Thiruvur; Garcia, Ana Maria; Gruenwald, Antje; Thomas, David B; Shatat, Ibrahim F; Supe, Katarine; Woroniecki, Robert P; Susztak, Katalin | Journal of the American Society of Nephrology : JASN. | 18443355 | 2008 May; |
| Acetylation is indispensable for p53 activation. | Tang, Yi; Zhao, Wenhui; Chen, Yue; Zhao, Yingming; Gu, Wei | Cell | 18485870 | 2008 May 16 |
| Smad1 as a biomarker for diabetic nephropathy. | Kato, Hideki; Si, Han; Hostetter, Thomas; Susztak, Katalin | Diabetes. | 18511448 | 2008 Jun; |
| Identification and verification of lysine propionylation and butyrylation in yeast core histones using PTMap software. | Zhang, Kai; Chen, Yue; Zhang, Zhihong; Zhao, Yingming | Journal of proteome research | 19113941 | 2009 Feb |
| Epigenetic changes in Alzheimer's disease: decrements in DNA methylation. | Mastroeni, Diego; Grover, Andrew; Delvaux, Elaine; Whiteside, Charisse; Coleman, Paul D; Rogers, Joseph | Neurobiology of aging | 19117641 | 2010 Dec |
| Next is now: new technologies for sequencing of genomes, transcriptomes, and beyond. | Lister, Ryan; Gregory, Brian D; Ecker, Joseph R | Current opinion in plant biology | 19157957 | 2009 Apr |
| Seed in soil, with an epigenetic view. | Lin, Huey-Jen L; Zuo, Tao; Chao, Jennifer R; Peng, Zhengang; Asamoto, Lisa K; Yamashita, Sonya S; Huang, Tim H-M | Biochimica et biophysica acta | 19162126 | 2009 Sep |
| Human and murine kidneys show gender- and species-specific gene expression differences in response to injury. | Si, Han; Banga, Ramandeep S; Kapitsinou, Pinelopi; Ramaiah, Manjunath; Lawrence, Janis; Kambhampati, Ganesh; Gruenwald, Antje; Bottinger, Erwin; Glicklich, Daniel; Tellis, Vivian; Greenstein, Stuart; Thomas, David B; Pullman, James; Fazzari, Melissa; Susztak, Katalin | PloS one. | 19277126 | 2009; |
| The importance of being tyrosine: lessons in molecular recognition from minimalist synthetic binding proteins. | Koide, Shohei; Sidhu, Sachdev S | ACS chemical biology | 19298050 | 2009 May 15 |
| Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. | Deng, Jie; Shoemaker, Robert; Xie, Bin; Gore, Athurva; LeProust, Emily M; Antosiewicz-Bourget, Jessica; Egli, Dieter; Maherali, Nimet; Park, In-Hyun; Yu, Junying; Daley, George Q; Eggan, Kevin; Hochedlinger, Konrad; Thomson, James; Wang, Wei; Gao, Yuan; Z | Nature biotechnology | 19330000 | 2009 Apr |
| Mascot-derived false positive peptide identifications revealed by manual analysis of tandem mass spectra. | Chen, Yue; Zhang, Junmei; Xing, Gang; Zhao, Yingming | Journal of proteome research | 19368407 | 2009 Jun |
| K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts. | Wijeratne, Subhashinee S K; Camporeale, Gabriela; Zempleni, Janos | The Journal of nutritional biochemistry | 19369050 | 2010 Apr |
| Epigenetic alterations in the breast: Implications for breast cancer detection, prognosis and treatment. | Dworkin, Amy M; Huang, Tim H-M; Toland, Amanda Ewart | Seminars in cancer biology | 19429480 | 2009 Jun |
| The ankyrin repeat domain of Huntingtin interacting protein 14 contains a surface aromatic cage, a potential site for methyl-lysine binding. | Gao, Tiyu; Collins, Robert E; Horton, John R; Zhang, Xing; Zhang, Rongguang; Dhayalan, Arunkumar; Tamas, Raluca; Jeltsch, Albert; Cheng, Xiaodong | Proteins | 19434754 | 2009 Aug 15 |
| A multicenter, double-blinded validation study of methylation biomarkers for progression prediction in Barrett's esophagus. | Jin, Zhe; Cheng, Yulan; Gu, Wen; Zheng, Yingye; Sato, Fumiaki; Mori, Yuriko; Olaru, Alexandru V; Paun, Bogdan C; Yang, Jian; Kan, Takatsugu; Ito, Tetsuo; Hamilton, James P; Selaru, Florin M; Agarwal, Rachana; David, Stefan; Abraham, John M; Wolfsen, Herbe | Cancer research | 19435894 | 2009 May 15 |
| High-throughput bisulfite sequencing in mammalian genomes. | Smith, Zachary D; Gu, Hongcang; Bock, Christoph; Gnirke, Andreas; Meissner, Alexander | Methods (San Diego, Calif.) | 19442738 | 2009 Jul |
| Engineering of recombinant crystallization chaperones. | Koide, Shohei | Current opinion in structural biology | 19477632 | 2009 Aug |
| Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing. | Varley, Katherine E; Mutch, David G; Edmonston, Tina B; Goodfellow, Paul J; Mitra, Robi D | Nucleic acids research | 19494183 | 2009 Aug |
| Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells. | Hsu, Pei-Yin; Deatherage, Daniel E; Rodriguez, Benjamin A T; Liyanarachchi, Sandya; Weng, Yu-I; Zuo, Tao; Liu, Joseph; Cheng, Alfred S L; Huang, Tim H-M | Cancer research | 19549897 | 2009 Jul 15 |
| A noncanonical bromodomain in the AAA ATPase protein Yta7 directs chromosomal positioning and barrier chromatin activity. | Gradolatto, Angeline; Smart, Sherri K; Byrum, Stephanie; Blair, Lauren P; Rogers, Richard S; Kolar, Elizabeth A; Lavender, Heather; Larson, Signe K; Aitchison, John D; Taverna, Sean D; Tackett, Alan J | Molecular and cellular biology | 19581291 | 2009 Sep |
| RAG: a recombinase diversified. | Matthews, Adam G W; Oettinger, Marjorie A | Nature immunology. | 19621044 | 2009 Aug; |
| Mapping the local protein interactome of the NuA3 histone acetyltransferase. | Smart, Sherri K; Mackintosh, Samuel G; Edmondson, Ricky D; Taverna, Sean D; Tackett, Alan J | Protein science : a publication of the Protein Society | 19621382 | 2009 Sep |
| BSMAP: whole genome bisulfite sequence MAPping program. | Xi, Yuanxin; Li, Wei | BMC bioinformatics | 19635165 | 2009 |
| Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution. | Huang, Jin; Makabe, Koki; Biancalana, Matthew; Koide, Akiko; Koide, Shohei | Journal of molecular biology | 19646997 | 2009 Oct 9 |
| Epigenetic events in gastrointestinal cancer. | Selaru, Florin M; David, Stefan; Meltzer, Stephen J; Hamilton, James P | The American journal of gastroenterology | 19661933 | 2009 Aug |
| Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma. | Akagi, Tadayuki; Ito, Tetsuo; Kato, Motohiro; Jin, Zhe; Cheng, Yulan; Kan, Takatsugu; Yamamoto, Go; Olaru, Alexandru; Kawamata, Norihiko; Boult, Jessica; Soukiasian, Harmik J; Miller, Carl W; Ogawa, Seishi; Meltzer, Stephen J; Koeffler, H Phillip | International journal of cancer. Journal international du cancer | 19670330 | 2009 Nov 15 |
| Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease. | Mastroeni, Diego; McKee, Ann; Grover, Andrew; Rogers, Joseph; Coleman, Paul D | PloS one | 19672297 | 2009 |
| Generation of new protein functions by nonhomologous combinations and rearrangements of domains and modules. | Koide, Shohei | Current opinion in biotechnology | 19700302 | 2009 Aug |
| Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes. | Zhang, Z; Song, L; Maurer, K; Petri, M A; Sullivan, K E | Genes and immunity | 19710693 | 2010 Mar |
| Viral-encoded enzymes that target host chromatin functions. | Wei H, Zhou MM. | Biochim Biophys Acta | 19716451 | 2010 Mar-Apr |
| Updates to the RMAP short-read mapping software. | Smith, Andrew D; Chung, Wen-Yu; Hodges, Emily; Kendall, Jude; Hannon, Greg; Hicks, James; Xuan, Zhenyu; Zhang, Michael Q | Bioinformatics (Oxford, England) | 19736251 | 2009 Nov 1 |
| Methylated DNA immunoprecipitation and microarray-based analysis: detection of DNA methylation in breast cancer cell lines. | Weng, Yu-I; Huang, Tim H-M; Yan, Pearlly S | Methods in molecular biology (Clifton, N.J.) | 19763503 | 2009 |
| HRTBLDb: an informative data resource for hormone receptors target binding loci. | Kennedy, Brian A; Gao, Wenqing; Huang, Tim H-M; Jin, Victor X | Nucleic acids research | 19773424 | 2010 Jan |
| Epithelial-mesenchymal transition and podocyte loss in diabetic kidney disease. | Reidy, Kimberly; Susztak, Katalin | American journal of kidney diseases : the official journal of the National Kidney Foundation | 19781451 | 2009 Oct |
| Repression of transposable elements by histone biotinylation. | Zempleni, Janos; Chew, Yap Ching; Bao, Baolong; Pestinger, Valerie; Wijeratne, Subhashinee S K | The Journal of nutrition | 19812216 | 2009 Dec |
| Human DNA methylomes at base resolution show widespread epigenomic differences. | Lister, Ryan; Pelizzola, Mattia; Dowen, Robert H; Hawkins, R David; Hon, Gary; Tonti-Filippini, Julian; Nery, Joseph R; Lee, Leonard; Ye, Zhen; Ngo, Que-Minh; Edsall, Lee; Antosiewicz-Bourget, Jessica; Stewart, Ron; Ruotti, Victor; Millar, A Harvey; Thoms | Nature | 19829295 | 2009 Nov 19 |
| Biotin tagging coupled with amino acid-coded mass tagging for efficient and precise screening of interaction proteome in mammalian cells. | He, Yu-Fei; Bao, Hui-Min; Xiao, Xiao-Feng; Zuo, Shuai; Du, Ru-Yun; Tang, Si-Wei; Yang, Peng-Yuan; Chen, Xian | Proteomics | 19834888 | 2009 Dec |
| MS/MS/MS reveals false positive identification of histone serine methylation. | Zhang, Junmei; Chen, Yue; Zhang, Zhihong; Xing, Gang; Wysocka, Joanna; Zhao, Yingming | Journal of proteome research | 19877717 | 2010 Jan |
| Identification of a functional network of human epigenetic silencing factors. | Poleshko, Andrey; Einarson, Margret B; Shalginskikh, Natalia; Zhang, Rugang; Adams, Peter D; Skalka, Anna Marie; Katz, Richard A | The Journal of biological chemistry | 19880521 | 2010 Jan 1 |
| A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics. | Quinn, Amy M; Bedford, Mark T; Espejo, Alexsandra; Spannhoff, Astrid; Austin, Christopher P; Oppermann, Udo; Simeonov, Anton | Nucleic acids research | 19897549 | 2010 Jan |
| Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective. | Jarboe, Elke A; Folkins, Ann K; Drapkin, Ronny; Ince, Tan A; Agoston, Elin S; Crum, Christopher P | Histopathology | 19912369 | 2009 Nov |
| A peptide tag system for facile purification and single-molecule immobilization. | Huang, Jin; Nagy, Stanislav S; Koide, Akiko; Rock, Ronald S; Koide, Shohei | Biochemistry | 19928925 | 2009 Dec 22 |
| Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks. | Bua, Dennis J; Kuo, Alex J; Cheung, Peggie; Liu, Chih Long; Migliori, Valentina; Espejo, Alexsandra; Casadio, Fabio; Bassi, Christian; Amati, Bruno; Bedford, Mark T; Guccione, Ernesto; Gozani, Or | PloS one | 19956676 | 2009 |
| Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma. | Yang, Xiaoli; Zou, Peng; Yao, Jun; Yun, Dong; Bao, Huimin; Du, Ruyun; Long, Jing; Chen, Xian | Journal of proteome research | 20000738 | 2010 Mar 5 |
| Epigenetics of neurological cancers. | Fouse, Shaun D; Costello, Joseph F | Future oncology (London, England). | 20001799 | 2009 Dec; |
| Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. | Horton, John R; Upadhyay, Anup K; Qi, Hank H; Zhang, Xing; Shi, Yang; Cheng, Xiaodong | Nature structural & molecular biology | 20023638 | 2010 Jan |
| Parylene peel-off arrays to probe the role of cell-cell interactions in tumour angiogenesis. | Tan CP, Seo BR, Brooks DJ, Chandler EM, Craighead HG, Fischbach C. | Integr Biol (Camb) | 20023775 | 2009 Oct |
| The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylation. | Hassan, Yousef I; Moriyama, Hideaki; Zempleni, Janos | Archives of biochemistry and biophysics | 20026029 | 2010 Mar 1 |
| Unrestrictive identification of non-phosphorylation PTMs in yeast kinases by MS and PTMap. | Zhang, Kai; Chen, Yue; Zhang, Zhihong; Tao, Shengce; Zhu, Heng; Zhao, Yingming | Proteomics | 20049863 | 2010 Mar |
| Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution. | Gu, Hongcang; Bock, Christoph; Mikkelsen, Tarjei S; Jager, Natalie; Smith, Zachary D; Tomazou, Eleni; Gnirke, Andreas; Lander, Eric S; Meissner, Alexander | Nature methods | 20062050 | 2010 Feb |
| Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. | Peng, Jamy C; Valouev, Anton; Swigut, Tomek; Zhang, Junmei; Zhao, Yingming; Sidow, Arend; Wysocka, Joanna | Cell | 20064375 | 2009 Dec 24 |
| Nanoscale resolution, multicomponent biomolecular arrays generated by aligned printing with parylene peel-off. | Tan, Christine P; Cipriany, Benjamin R; Lin, David M; Craighead, Harold G | Nano letters | 20088589 | 2010 Feb 10 |
| CHD7 cooperates with PBAF to control multipotent neural crest formation. | Bajpai, Ruchi; Chen, Denise A; Rada-Iglesias, Alvaro; Zhang, Junmei; Xiong, Yiqin; Helms, Jill; Chang, Ching-Pin; Zhao, Yingming; Swigut, Tomek; Wysocka, Joanna | Nature | 20130577 | 2010 Feb 18 |
| Structure of the MADS-box/MEF2 domain of MEF2A bound to DNA and its implication for myocardin recruitment. | Wu Y, Dey R, Han A, Jayathilaka N, Philips M, Ye J, Chen L. | J Mol Biol | 20132824 | 2010 Mar 26 |
| Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae. | Baker, Stephen P; Phillips, Jennifer; Anderson, Scott; Qiu, Qifeng; Shabanowitz, Jeffrey; Smith, M Mitchell; Yates 3rd, John R; Hunt, Donald F; Grant, Patrick A | Nature cell biology | 20139971 | 2010 Mar |
| Transcriptome study for early hematopoiesis--achievement, challenge and new opportunity. | Wang, San Ming; Zhang, Michael Q | Journal of cellular physiology | 20143329 | 2010 Jun |
| Rational conversion of affinity reagents into label-free sensors for Peptide motifs by designed allostery. | Huang, Jin; Koide, Shohei | ACS chemical biology | 20143785 | 2010 Mar 19 |
| A case study in cross-talk: the histone lysine methyltransferases G9a and GLP. | Collins R, Cheng X. | Nucleic Acids Res | 20159995 | 2010 Jun |
| Single molecule epigenetic analysis in a nanofluidic channel. | Cipriany, Benjamin R; Zhao, Ruqian; Murphy, Patrick J; Levy, Stephen L; Tan, Christine P; Craighead, Harold G; Soloway, Paul D | Analytical chemistry | 20184350 | 2010 Mar 15 |
| Bioorthogonal chemical reporters for monitoring protein acetylation. | Yang, Yu-Ying; Ascano, Janice M; Hang, Howard C | Journal of the American Chemical Society | 20192265 | 2010 Mar 24 |
| Coordinated chromatin control: structural and functional linkage of DNA and histone methylation. | Cheng X, Blumenthal RM. | Biochemistry | 20210320 | 2010 Apr 13 |
| Rapid visualization and large-scale profiling of bacterial lipoproteins with chemical reporters. | Rangan, Kavita J; Yang, Yu-Ying; Charron, Guillaume; Hang, Howard C | Journal of the American Chemical Society | 20230003 | 2010 Aug 11 |
| DNA methylation profiling using the methylated-CpG island recovery assay (MIRA). | Rauch, Tibor A; Pfeifer, Gerd P | Methods (San Diego, Calif.) | 20304072 | 2010 Nov |
| Biotin requirements are lower in human Jurkat lymphoid cells but homeostatic mechanisms are similar to those of HepG2 liver cells. | Mall, Gaganpreet Kaur; Chew, Yap Ching; Zempleni, Janos | The Journal of nutrition | 20357078 | 2010 Jun |
| Epigenetic approaches to psychiatric disorders. | Ptak, Carolyn; Petronis, Arturas | Dialogues in clinical neuroscience | 20373664 | 2010 |
| Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome. | Shoemaker, Robert; Deng, Jie; Wang, Wei; Zhang, Kun | Genome research | 20418490 | 2010 Jul |
| Successful computational prediction of novel imprinted genes from epigenomic features. | Brideau, Chelsea M; Eilertson, Kirsten E; Hagarman, James A; Bustamante, Carlos D; Soloway, Paul D | Molecular and cellular biology | 20421412 | 2010 Jul |
| HP1: heterochromatin binding proteins working the genome. | Zeng, Weihua; Ball Jr, Alexander R; Yokomori, Kyoko | Epigenetics : official journal of the DNA Methylation Society | 20421743 | 2010 May 16 |
| Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. | Chang, Yanqi; Ganesh, Thota; Horton, John R; Spannhoff, Astrid; Liu, Jin; Sun, Aiming; Zhang, Xing; Bedford, Mark T; Shinkai, Yoichi; Snyder, James P; Cheng, Xiaodong | Journal of molecular biology | 20434463 | 2010 Jul 2 |
| c-Myc regulates transcriptional pause release. | Rahl, Peter B; Lin, Charles Y; Seila, Amy C; Flynn, Ryan A; McCuine, Scott; Burge, Christopher B; Sharp, Phillip A; Young, Richard A | Cell | 20434984 | 2010 Apr 30 |
| Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping. | Hsu, Pei-Yin; Hsu, Hang-Kai; Singer, Gregory A C; Yan, Pearlly S; Rodriguez, Benjamin A T; Liu, Joseph C; Weng, Yu-I; Deatherage, Daniel E; Chen, Zhong; Pereira, Julia S; Lopez, Ricardo; Russo, Jose; Wang, Qianben; Lamartiniere, Coral A; Nephew, Kenneth P | Genome research | 20442245 | 2010 Jun |
| Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. | Hawkins, R David; Hon, Gary C; Lee, Leonard K; Ngo, Queminh; Lister, Ryan; Pelizzola, Mattia; Edsall, Lee E; Kuan, Samantha; Luu, Ying; Klugman, Sarit; Antosiewicz-Bourget, Jessica; Ye, Zhen; Espinoza, Celso; Agarwahl, Saurabh; Shen, Li; Ruotti, Victor; W | Cell stem cell | 20452322 | 2010 May 7 |
| Unveiling the vasodilatory actions and mechanisms of relaxin. | Conrad, Kirk P | Hypertension (Dallas, Tex. : 1979) | 20497994 | 2010 Jul |
| Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. | Deal, Roger B; Henikoff, Jorja G; Henikoff, Steven | Science (New York, N.Y.) | 20508129 | 2010 May 28 |
| Methods in DNA methylation profiling. | Zuo, Tao; Tycko, Benjamin; Liu, Ta-Ming; Lin, Juey-Jen L; Huang, Tim H-M | Epigenomics | 20526417 | 2009 Dec |
| Next-generation genomics: an integrative approach. | Hawkins, R David; Hon, Gary C; Ren, Bing | Nature reviews. Genetics | 20531367 | 2010 Jul |
| Epigenetics as a unifying principle in the aetiology of complex traits and diseases. | Petronis, Arturas | Nature | 20535201 | 2010 Jun 10 |
| Hormonal influences on cognition and risk for Alzheimer's disease. | Janicki, Sarah C; Schupf, Nicole | Current neurology and neuroscience reports | 20535591 | 2010 Sep |
| Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. | Yap KL, Li S, Muñoz-Cabello AM, Raguz S, Zeng L, Mujtaba S, Gil J, Walsh MJ, Zhou MM. | Mol Cell | 20541999 | 2010 Jun 11 |
| The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation. | Dhayalan A, Rajavelu A, Rathert P, Tamas R, Jurkowska RZ, Ragozin S, Jeltsch A. | J Biol Chem | 20547484 | 2010 Aug 20 |
| The roles of PARP1 in gene control and cell differentiation. | Ji, Yingbiao; Tulin, Alexei V | Current opinion in genetics & development | 20591646 | 2010 Oct |
| Biotin regulates the expression of holocarboxylase synthetase in the miR-539 pathway in HEK-293 cells. | Bao, Baolong; Rodriguez-Melendez, Rocio; Wijeratne, Subhashinee S K; Zempleni, Janos | The Journal of nutrition | 20592104 | 2010 Sep |
| Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3. | Yount, Jacob S; Moltedo, Bruno; Yang, Yu-Ying; Charron, Guillaume; Moran, Thomas M; Lopez, Carolina B; Hang, Howard C | Nature chemical biology | 20601941 | 2010 Aug |
| Chromatin remodeling in mammary gland differentiation and breast tumorigenesis. | Huang, Tim H-M; Esteller, Manel | Cold Spring Harbor perspectives in biology | 20610549 | 2010 Sep |
| Conserved role of intragenic DNA methylation in regulating alternative promoters. | Maunakea, Alika K; Nagarajan, Raman P; Bilenky, Mikhail; Ballinger, Tracy J; D'Souza, Cletus; Fouse, Shaun D; Johnson, Brett E; Hong, Chibo; Nielsen, Cydney; Zhao, Yongjun; Turecki, Gustavo; Delaney, Allen; Varhol, Richard; Thiessen, Nina; Shchors, Ksenya; Heine, Vivi M; Rowitch, David H; Xing, Xiaoyun; Fiore, Chris; Schillebeeckx, Maximiliaan; Jones, Steven J M; Haussler, David; Marra, Marco A; Hirst, Martin; Wang, Ting; Costello, Joseph F | Nature. | 20613842 | 2010 Jul 8; |
| Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines. | Liu F, Chen X, Allali-Hassani A, Quinn AM, Wigle TJ, Wasney GA, Dong A, Senisterra G, Chau I, Siarheyeva A, Norris JL, Kireev DB, Jadhav A, Herold JM, Janzen WP, Arrowsmith CH, Frye SV, Brown PJ, Simeonov A, Vedadi M, Jin J. | J Med Chem | 20614940 | 2010 Aug 12 |
| Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors. | Adli, Mazhar; Zhu, Jiang; Bernstein, Bradley E | Nature methods | 20622861 | 2010 Aug |
| Cytokine-induced monocyte characteristics in SLE. | Zhang, Zhe; Maurer, Kelly; Perin, Juan C; Song, Li; Sullivan, Kathleen E | Journal of biomedicine & biotechnology | 20625490 | 2010 |
| Bisulfite Patch PCR enables multiplexed sequencing of promoter methylation across cancer samples. | Varley, Katherine Elena; Mitra, Robi David | Genome research | 20627893 | 2010 Sep |
| Histone deacetylase inhibitor, MS-275, exhibits poor brain penetration: PK studies of [C]MS-275 using Positron Emission Tomography. | Hooker, Jacob M; Kim, Sung Won; Alexoff, David; Xu, Youwen; Shea, Colleen; Reid, Alicia; Volkow, Nora; Fowler, Joanna S | ACS chemical neuroscience | 20657706 | 2010 |
| Accessing protein methyltransferase and demethylase enzymology using microfluidic capillary electrophoresis. | Wigle TJ, Provencher LM, Norris JL, Jin J, Brown PJ, Frye SV, Janzen WP. | Chem Biol | 20659682 | 2010 Jul 30 |
| Epigenetic influences of low-dose bisphenol A in primary human breast epithelial cells. | Weng, Yu-I; Hsu, Pei-Yin; Liyanarachchi, Sandya; Liu, Joseph; Deatherage, Daniel E; Huang, Yi-Wen; Zuo, Tao; Rodriguez, Benjamin; Lin, Ching-Hung; Cheng, Ann-Lii; Huang, Tim H-M | Toxicology and applied pharmacology | 20678512 | 2010 Oct 15 |
| Actin-myosin contractility is responsible for the reduced viability of dissociated human embryonic stem cells. | Chen, Guokai; Hou, Zhonggang; Gulbranson, Daniel R; Thomson, James A | Cell stem cell | 20682449 | 2010 Aug 6 |
| Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. | Guenther, Matthew G; Frampton, Garrett M; Soldner, Frank; Hockemeyer, Dirk; Mitalipova, Maya; Jaenisch, Rudolf; Young, Richard A | Cell stem cell | 20682450 | 2010 Aug 6 |
| SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. | Kashyap, Manoj Kumar; Harsha, H C; Renuse, Santosh; Pawar, Harsh; Sahasrabuddhe, Nandini A; Kim, Min-Sik; Marimuthu, Arivusudar; Keerthikumar, Shivakumar; Muthusamy, Babylakshmi; Kandasamy, Kumaran; Subbannayya, Yashwanth; Prasad, Thottethodi Subrahmanya | Cancer biology & therapy | 20686364 | 2010 Oct 15 |
| Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18. | Bao, Baolong; Pestinger, Valerie; Hassan, Yousef I; Borgstahl, Gloria E O; Kolar, Carol; Zempleni, Janos | The Journal of nutritional biochemistry | 20688500 | 2011 May |
| Novel histone biotinylation marks are enriched in repeat regions and participate in repression of transcriptionally competent genes. | Pestinger, Valerie; Wijeratne, Subhashinee S K; Rodriguez-Melendez, Rocio; Zempleni, Janos | The Journal of nutritional biochemistry | 20691578 | 2011 Apr |
| Predicting conversion from mild cognitive impairment to Alzheimer's disease using neuropsychological tests and multivariate methods. | Chapman, Robert M; Mapstone, Mark; McCrary, John W; Gardner, Margaret N; Porsteinsson, Anton; Sandoval, Tiffany C; Guillily, Maria D; Degrush, Elizabeth; Reilly, Lindsey A | Journal of clinical and experimental neuropsychology | 20711906 | 2011 Feb |
| Change in risk of Alzheimer disease over time. | Hebert, L E; Bienias, J L; Aggarwal, N T; Wilson, R S; Bennett, D A; Shah, R C; Evans, D A | Neurology | 20805524 | 2010 Aug 31 |
| The first global screening of protein substrates bearing protein-bound 3,4-Dihydroxyphenylalanine in Escherichia coli and human mitochondria. | Lee, Sangkyu; Chen, Yue; Luo, Hao; Wu, Andrew A; Wilde, Michael; Schumacker, Paul T; Zhao, Yingming | Journal of proteome research | 20818827 | 2010 Nov 5 |
| Quantitative comparison of genome-wide DNA methylation mapping technologies. | Bock, Christoph; Tomazou, Eleni M; Brinkman, Arie B; Muller, Fabian; Simmer, Femke; Gu, Hongcang; Jager, Natalie; Gnirke, Andreas; Stunnenberg, Hendrik G; Meissner, Alexander | Nature biotechnology | 20852634 | 2010 Oct |
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| A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis. | Guan, Yuting; Liang, Xiujie; Ma, Ziyuan; Hu, Hailong; Liu, Hongbo; Miao, Zhen; Linkermann, Andreas; Hellwege, Jacklyn N; Voight, Benjamin F; Susztak, Katalin | Nature communications | 34426578 | 2021 08 23 |
| Manipulating the NKG2D Receptor-Ligand Axis Using CRISPR: Novel Technologies for Improved Host Immunity. | Alves, Eric; McLeish, Emily; Blancafort, Pilar; Coudert, Jerome D; Gaudieri, Silvana | Frontiers in immunology | 34456921 | 2021 |
| Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer's dementia: a network Mendelian randomization analysis. | Liu, Di; Wang, Youxin; Jing, Huiquan; Meng, Qun; Yang, Jingyun | Epigenetics | 34461811 | 2022 Jun-Jul |
| Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans. | Ma, Yiyi; Yu, Lei; Olah, Marta; Smith, Rebecca; Oatman, Stephanie R; Allen, Mariet; Pishva, Ehsan; Zhang, Bin; Menon, Vilas; Ertekin-Taner, Nilüfer; Lunnon, Katie; Bennett, David A; Klein, Hans-Ulrich; De Jager, Philip L | Alzheimer's & dementia : the journal of the Alzheimer's Association | 34482628 | 2021 Sep 05 |
| Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences. | Zhan, Lingyu; Li, Jiajin; Jew, Brandon; Sul, Jae Hoon | PLoS genetics | 34516545 | 2021 Sep |
| Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons. | Kalmbach, Brian E; Hodge, Rebecca D; Jorstad, Nikolas L; Owen, Scott; de Frates, Rebecca; Yanny, Anna Marie; Dalley, Rachel; Mallory, Matt; Graybuck, Lucas T; Radaelli, Cristina; Keene, C Dirk; Gwinn, Ryder P; Silbergeld, Daniel L; Cobbs, Charles; Ojemann, Jeffrey G; Ko, Andrew L; Patel, Anoop P; Ellenbogen, Richard G; Bakken, Trygve E; Daigle, Tanya L; Dee, Nick; Lee, Brian R; McGraw, Medea; Nicovich, Philip R; Smith, Kimberly; Sorensen, Staci A; Tasic, Bosiljka; Zeng, Hongkui; Koch, Christof; Lein, Ed S; Ting, Jonathan T | Neuron | 34534454 | 2021 09 15 |
| Olfactory Bulb and Amygdala Gene Expression Changes in Subjects Dying with COVID-19. | Piras, Ignazio S; Huentelman, Matthew J; Walker, Jessica E; Arce, Richard; Glass, Michael J; Vargas, Daisy; Sue, Lucia I; Intorcia, Anthony J; Nelson, Courtney M; Suszczewicz, Katsuko E; Borja, Claryssa L; Desforges, Marc; Deture, Michael; Dickson, Dennis W; Beach, Thomas G; Serrano, Geidy E | medRxiv : the preprint server for health sciences | 34545375 | 2021 Sep 15 |
| Longitudinal urinary biomarkers of immunological activation in covid-19 patients without clinically apparent kidney disease versus acute and chronic failure. | Laudanski, Krzysztof; Okeke, Tony; Jihane, Hajj; Siddiq, Kumal; Rader, Daniel J; Wu, Junnan; Susztak, Katalin | Scientific reports | 34608231 | 2021 10 04 |
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| Research Priorities for Kidney-Related Research-An Agenda to Advance Kidney Care: A Position Statement From the National Kidney Foundation. | National Kidney Foundation Research Roundtable Work Group on behalf of the National Kidney Foundation | American journal of kidney diseases : the official journal of the National Kidney Foundation | 34627932 | 2022 Feb |
| Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance. | Yousefi, Soheil; Deng, Ruizhi; Lanko, Kristina; Salsench, Eva Medico; Nikoncuk, Anita; van der Linde, Herma C; Perenthaler, Elena; van Ham, Tjakko J; Mulugeta, Eskeatnaf; Barakat, Tahsin Stefan | Genome medicine | 34663447 | 2021 Oct 19 |
| Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases. | Lam, Simon; Hartmann, Nils; Benfeitas, Rui; Zhang, Cheng; Arif, Muhammad; Turkez, Hasan; Uhlén, Mathias; Englert, Christoph; Knight, Robert; Mardinoglu, Adil | Biomedicines | 34680427 | 2021 Sep 24 |
| APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis. | Wu, Junnan; Ma, Ziyuan; Raman, Archana; Beckerman, Pazit; Dhillon, Poonam; Mukhi, Dhanunjay; Palmer, Matthew; Chen, Hua Chang; Cohen, Cassiane Robinson; Dunn, Thomas; Reilly, John; Meyer, Nuala; Shahaty, Michael; Arany, Zoltan; Haskó, György; Laudanski, Krzysztof; Hung, Adriana; Susztak, Katalin | Immunity | 34715018 | 2021 11 09 |
| Genome-wide association studies identify the role of caspase-9 in kidney disease. | Doke, Tomohito; Huang, Shizheng; Qiu, Chengxiang; Sheng, Xin; Seasock, Matthew; Liu, Hongbo; Ma, Ziyuan; Palmer, Matthew; Susztak, Katalin | Science advances | 34739325 | 2021 Nov 05 |
| From mapping kidney function to mechanism and prediction. | Hirohama, Daigoro; Susztak, Katalin | Nature reviews. Nephrology | 34819631 | 2022 02 |
| How Many Cell Types Are in the Kidney and What Do They Do? | Balzer, Michael S; Rohacs, Tibor; Susztak, Katalin | Annual review of physiology | 34843404 | 2022 02 10 |
| Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue. | Ma, Yiyi; Dammer, Eric B; Felsky, Daniel; Duong, Duc M; Klein, Hans-Ulrich; White, Charles C; Zhou, Maotian; Logsdon, Benjamin A; McCabe, Cristin; Xu, Jishu; Wang, Minghui; Wingo, Thomas S; Lah, James J; Zhang, Bin; Schneider, Julie; Allen, Mariet; Wang, Xue; Ertekin-Taner, Nilüfer; Seyfried, Nicholas T; Levey, Allan I; Bennett, David A; De Jager, Philip L | Nature communications | 34857756 | 2021 12 02 |
| Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome. | Zeng, Yanni; Amador, Carmen; Gao, Chenhao; Walker, Rosie M; Morris, Stewart W; Campbell, Archie; Frkatović, Azra; Madden, Rebecca A; Adams, Mark J; He, Shuai; Bretherick, Andrew D; Hayward, Caroline; Porteous, David J; Wilson, James F; Evans, Kathryn L; McIntosh, Andrew M; Navarro, Pau; Haley, Chris S | EBioMedicine | 34883445 | 2021 Dec |
| Bayesian Sparse Mediation Analysis with Targeted Penalization of Natural Indirect Effects. | Song, Yanyi; Zhou, Xiang; Kang, Jian; Aung, Max T; Zhang, Min; Zhao, Wei; Needham, Belinda L; Kardia, Sharon L R; Liu, Yongmei; Meeker, John D; Smith, Jennifer A; Mukherjee, Bhramar | Journal of the Royal Statistical Society. Series C, Applied statistics | 34887595 | 2021 Nov |
| AtheroSpectrum Reveals Novel Macrophage Foam Cell Gene Signatures Associated With Atherosclerotic Cardiovascular Disease Risk. | Li, Chuan; Qu, Lili; Matz, Alyssa J; Murphy, Patrick A; Liu, Yongmei; Manichaikul, Ani W; Aguiar, Derek; Rich, Stephen S; Herrington, David M; Vu, David; Johnson, W Craig; Rotter, Jerome I; Post, Wendy S; Vella, Anthony T; Rodriguez-Oquendo, Annabelle; Zhou, Beiyan | Circulation | 34913723 | 2022 Jan 18 |
| Integrated Genomic, Transcriptomic and Proteomic Analysis for Identifying Markers of Alzheimer's Disease. | Madrid, Laura; Labrador, Sandra C; González-Pérez, Antonio; Sáez, María E; The Alzheimer's Disease Neuroimaging Initiative Adni | Diagnostics (Basel, Switzerland) | 34943540 | 2021 Dec 08 |
| Monocyte miRNAs Are Associated With Type 2 Diabetes. | Parker, Daniel C; Wan, Ma; Lohman, Kurt; Hou, Li; Nguyen, Anh Tram; Ding, Jingzhong; Bertoni, Alain; Shea, Steve; Burke, Gregory L; Jacobs, David R; Post, Wendy; Corcoran, David; Hoeschele, Ina; Parks, John S; Liu, Yongmei | Diabetes | 35073575 | 2022 Apr 01 |
| Brain microRNAs are associated with variation in cognitive trajectory in advanced age. | Wingo, Aliza P; Wang, Mengli; Liu, Jiaqi; Breen, Michael S; Yang, Hyun-Sik; Tang, Beisha; Schneider, Julie A; Seyfried, Nicholas T; Lah, James J; Levey, Allan I; Bennett, David A; Jin, Peng; De Jager, Philip L; Wingo, Thomas S | Translational psychiatry | 35105862 | 2022 Feb 01 |
| Multi-transcriptomic analysis points to early organelle dysfunction in human astrocytes in Alzheimer's disease. | Galea, Elena; Weinstock, Laura D; Larramona-Arcas, Raquel; Pybus, Alyssa F; Giménez-Llort, Lydia; Escartin, Carole; Wood, Levi B | Neurobiology of disease | 35143967 | 2022 05 |
| MOMA: a multi-task attention learning algorithm for multi-omics data interpretation and classification. | Moon, Sehwan; Lee, Hyunju | Bioinformatics (Oxford, England) | 35157023 | 2022 Apr 12 |
| Local connectivity and synaptic dynamics in mouse and human neocortex. | Campagnola, Luke; Seeman, Stephanie C; Chartrand, Thomas; Kim, Lisa; Hoggarth, Alex; Gamlin, Clare; Ito, Shinya; Trinh, Jessica; Davoudian, Pasha; Radaelli, Cristina; Kim, Mean-Hwan; Hage, Travis; Braun, Thomas; Alfiler, Lauren; Andrade, Julia; Bohn, Phillip; Dalley, Rachel; Henry, Alex; Kebede, Sara; Alice, Mukora; Sandman, David; Williams, Grace; Larsen, Rachael; Teeter, Corinne; Daigle, Tanya L; Berry, Kyla; Dotson, Nadia; Enstrom, Rachel; Gorham, Melissa; Hupp, Madie; Dingman Lee, Samuel; Ngo, Kiet; Nicovich, Philip R; Potekhina, Lydia; Ransford, Shea; Gary, Amanda; Goldy, Jeff; McMillen, Delissa; Pham, Trangthanh; Tieu, Michael; Siverts, La'Akea; Walker, Miranda; Farrell, Colin; Schroedter, Martin; Slaughterbeck, Cliff; Cobb, Charles; Ellenbogen, Richard; Gwinn, Ryder P; Keene, C Dirk; Ko, Andrew L; Ojemann, Jeffrey G; Silbergeld, Daniel L; Carey, Daniel; Casper, Tamara; Crichton, Kirsten; Clark, Michael; Dee, Nick; Ellingwood, Lauren; Gloe, Jessica; Kroll, Matthew; Sulc, Josef; Tung, Herman; Wadhwani, Katherine; Brouner, Krissy; Egdorf, Tom; Maxwell, Michelle; McGraw, Medea; Pom, Christina Alice; Ruiz, Augustin; Bomben, Jasmine; Feng, David; Hejazinia, Nika; Shi, Shu; Szafer, Aaron; Wakeman, Wayne; Phillips, John; Bernard, Amy; Esposito, Luke; D'Orazi, Florence D; Sunkin, Susan; Smith, Kimberly; Tasic, Bosiljka; Arkhipov, Anton; Sorensen, Staci; Lein, Ed; Koch, Christof; Murphy, Gabe; Zeng, Hongkui; Jarsky, Tim | Science (New York, N.Y.) | 35271334 | 2022 03 11 |
| A single-cell atlas of human and mouse white adipose tissue. | Emont, Margo P; Jacobs, Christopher; Essene, Adam L; Pant, Deepti; Tenen, Danielle; Colleluori, Georgia; Di Vincenzo, Angelica; Jørgensen, Anja M; Dashti, Hesam; Stefek, Adam; McGonagle, Elizabeth; Strobel, Sophie; Laber, Samantha; Agrawal, Saaket; Westcott, Gregory P; Kar, Amrita; Veregge, Molly L; Gulko, Anton; Srinivasan, Harini; Kramer, Zachary; De Filippis, Eleanna; Merkel, Erin; Ducie, Jennifer; Boyd, Christopher G; Gourash, William; Courcoulas, Anita; Lin, Samuel J; Lee, Bernard T; Morris, Donald; Tobias, Adam; Khera, Amit V; Claussnitzer, Melina; Pers, Tune H; Giordano, Antonio; Ashenberg, Orr; Regev, Aviv; Tsai, Linus T; Rosen, Evan D | Nature | 35296864 | 2022 Mar |
| New insights into the genetic etiology of Alzheimer's disease and related dementias. | Bellenguez, Céline; Küçükali, Fahri; Jansen, Iris E; Kleineidam, Luca; Moreno-Grau, Sonia; Amin, Najaf; Naj, Adam C; Campos-Martin, Rafael; Grenier-Boley, Benjamin; Andrade, Victor; Holmans, Peter A; Boland, Anne; Damotte, Vincent; van der Lee, Sven J; Costa, Marcos R; Kuulasmaa, Teemu; Yang, Qiong; de Rojas, Itziar; Bis, Joshua C; Yaqub, Amber; Prokic, Ivana; Chapuis, Julien; Ahmad, Shahzad; Giedraitis, Vilmantas; Aarsland, Dag; Garcia-Gonzalez, Pablo; Abdelnour, Carla; Alarcón-Martín, Emilio; Alcolea, Daniel; Alegret, Montserrat; Alvarez, Ignacio; Álvarez, Victoria; Armstrong, Nicola J; Tsolaki, Anthoula; Antúnez, Carmen; Appollonio, Ildebrando; Arcaro, Marina; Archetti, Silvana; Pastor, Alfonso Arias; Arosio, Beatrice; Athanasiu, Lavinia; Bailly, Henri; Banaj, Nerisa; Baquero, Miquel; Barral, Sandra; Beiser, Alexa; Pastor, Ana Belén; Below, Jennifer E; Benchek, Penelope; Benussi, Luisa; Berr, Claudine; Besse, Céline; Bessi, Valentina; Binetti, Giuliano; Bizarro, Alessandra; Blesa, Rafael; Boada, Mercè; Boerwinkle, Eric; Borroni, Barbara; Boschi, Silvia; Bossù, Paola; Bråthen, Geir; Bressler, Jan; Bresner, Catherine; Brodaty, Henry; Brookes, Keeley J; Brusco, Luis Ignacio; Buiza-Rueda, Dolores; Bûrger, Katharina; Burholt, Vanessa; Bush, William S; Calero, Miguel; Cantwell, Laura B; Chene, Geneviève; Chung, Jaeyoon; Cuccaro, Michael L; Carracedo, Ángel; Cecchetti, Roberta; Cervera-Carles, Laura; Charbonnier, Camille; Chen, Hung-Hsin; Chillotti, Caterina; Ciccone, Simona; Claassen, Jurgen A H R; Clark, Christopher; Conti, Elisa; Corma-Gómez, Anaïs; Costantini, Emanuele; Custodero, Carlo; Daian, Delphine; Dalmasso, Maria Carolina; Daniele, Antonio; Dardiotis, Efthimios; Dartigues, Jean-François; de Deyn, Peter Paul; de Paiva Lopes, Katia; de Witte, Lot D; Debette, Stéphanie; Deckert, Jürgen; Del Ser, Teodoro; Denning, Nicola; DeStefano, Anita; Dichgans, Martin; Diehl-Schmid, Janine; Diez-Fairen, Mónica; Rossi, Paolo Dionigi; Djurovic, Srdjan; Duron, Emmanuelle; Düzel, Emrah; Dufouil, Carole; Eiriksdottir, Gudny; Engelborghs, Sebastiaan; Escott-Price, Valentina; Espinosa, Ana; Ewers, Michael; Faber, Kelley M; Fabrizio, Tagliavini; Nielsen, Sune Fallgaard; Fardo, David W; Farotti, Lucia; Fenoglio, Chiara; Fernández-Fuertes, Marta; Ferrari, Raffaele; Ferreira, Catarina B; Ferri, Evelyn; Fin, Bertrand; Fischer, Peter; Fladby, Tormod; Fließbach, Klaus; Fongang, Bernard; Fornage, Myriam; Fortea, Juan; Foroud, Tatiana M; Fostinelli, Silvia; Fox, Nick C; Franco-Macías, Emlio; Bullido, María J; Frank-García, Ana; Froelich, Lutz; Fulton-Howard, Brian; Galimberti, Daniela; García-Alberca, Jose Maria; García-González, Pablo; Garcia-Madrona, Sebastian; Garcia-Ribas, Guillermo; Ghidoni, Roberta; Giegling, Ina; Giorgio, Giaccone; Goate, Alison M; Goldhardt, Oliver; Gomez-Fonseca, Duber; González-Pérez, Antonio; Graff, Caroline; Grande, Giulia; Green, Emma; Grimmer, Timo; Grünblatt, Edna; Grunin, Michelle; Gudnason, Vilmundur; Guetta-Baranes, Tamar; Haapasalo, Annakaisa; Hadjigeorgiou, Georgios; Haines, Jonathan L; Hamilton-Nelson, Kara L; Hampel, Harald; Hanon, Olivier; Hardy, John; Hartmann, Annette M; Hausner, Lucrezia; Harwood, Janet; Heilmann-Heimbach, Stefanie; Helisalmi, Seppo; Heneka, Michael T; Hernández, Isabel; Herrmann, Martin J; Hoffmann, Per; Holmes, Clive; Holstege, Henne; Vilas, Raquel Huerto; Hulsman, Marc; Humphrey, Jack; Biessels, Geert Jan; Jian, Xueqiu; Johansson, Charlotte; Jun, Gyungah R; Kastumata, Yuriko; Kauwe, John; Kehoe, Patrick G; Kilander, Lena; Ståhlbom, Anne Kinhult; Kivipelto, Miia; Koivisto, Anne; Kornhuber, Johannes (see original citation for additional authors) | Nature genetics | 35379992 | 2022 04 |
| Transcriptional landscape of human microglia implicates age, sex, and APOE-related immunometabolic pathway perturbations. | Patel, Tulsi; Carnwath, Troy P; Wang, Xue; Allen, Mariet; Lincoln, Sarah J; Lewis-Tuffin, Laura J; Quicksall, Zachary S; Lin, Shu; Tutor-New, Frederick Q; Ho, Charlotte C G; Min, Yuhao; Malphrus, Kimberly G; Nguyen, Thuy T; Martin, Elizabeth; Garcia, Cesar A; Alkharboosh, Rawan M; Grewal, Sanjeet; Chaichana, Kaisorn; Wharen, Robert; Guerrero-Cazares, Hugo; Quinones-Hinojosa, Alfredo; Ertekin-Taner, Nilüfer | Aging cell | 35388616 | 2022 May |
| Distinct developmental phenotypes result from mutation of Set8/KMT5A and histone H4 lysine 20 in Drosophila melanogaster. | Crain, Aaron T; Klusza, Stephen; Armstrong, Robin L; Santa Rosa, Priscila; Temple, Brenda R S; Strahl, Brian D; McKay, Daniel J; Matera, A Gregory; Duronio, Robert J | Genetics | 35404465 | 2022 May 31 |
| Antisense oligonucleotides ameliorate kidney dysfunction in podocyte-specific APOL1 risk variant mice. | Yang, Ya-Wen; Poudel, Bibek; Frederick, Julia; Dhillon, Poonam; Shrestha, Rojesh; Ma, Ziyuan; Wu, Junnan; Okamoto, Koji; Kopp, Jeffrey B; Booten, Sheri L; Gattis, Danielle; Watt, Andrew T; Palmer, Matthew; Aghajan, Mariam; Susztak, Katalin | Molecular therapy : the journal of the American Society of Gene Therapy | 35450819 | 2022 Jul 06 |
| The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development. | Doke, Tomohito; Susztak, Katalin | Trends in cell biology | 35473814 | 2022 Oct |
| Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis. | Doke, Tomohito; Abedini, Amin; Aldridge, Daniel L; Yang, Ya-Wen; Park, Jihwan; Hernandez, Christina M; Balzer, Michael S; Shrestra, Rojesh; Coppock, Gaia; Rico, Juan M Inclan; Han, Seung Yub; Kim, Junhyong; Xin, Sheng; Piliponsky, Adrian M; Angelozzi, Marco; Lefebvre, Veronique; Siracusa, Mark C; Hunter, Christopher A; Susztak, Katalin | Nature immunology | 35552540 | 2022 May 12 |
| Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis. | Karlow, Jennifer A; Devarakonda, Siddhartha; Xing, Xiaoyun; Jang, Hyo Sik; Govindan, Ramaswamy; Watson, Mark; Wang, Ting | Cancer research | 35706127 | 2022 Aug 03 |
| Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease. | Liu, Hongbo; Doke, Tomohito; Guo, Dong; Sheng, Xin; Ma, Ziyuan; Park, Joseph; Vy, Ha My T; Nadkarni, Girish N; Abedini, Amin; Miao, Zhen; Palmer, Matthew; Voight, Benjamin F; Li, Hongzhe; Brown, Christopher D; Ritchie, Marylyn D; Shu, Yan; Susztak, Katalin | Nature genetics | 35710981 | 2022 07 |
| The association between aging-related monocyte transcriptional networks and comorbidity burden: the Multi-Ethnic Study of Atherosclerosis (MESA). | Ding, Jingzhong; Lohman, Kurt; Molina, Anthony; Delbono, Osvaldo; Bertoni, Alain; Shea, Steven; Post, Wendy; Guo, Xiuqing; Barr, R Graham; Manichaikul, Ani W; Pankow, James S; Rotter, Jerome I; Hoeschele, Ina; Kritchevsky, Stephen B; Liu, Yongmei | GeroScience | 35737188 | 2023 Feb |
| Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFκB p50 recruitment. | Burns, Veronica Elizabeth; Kerppola, Tom Klaus | Immunology | 35751391 | 2022 Sep |
| Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women. | Chung, Jaeyoon; Das, Anjali; Sun, Xinyu; Sobreira, Débora R; Leung, Yuk Yee; Igartua, Catherine; Mozaffari, Sahar; Chou, Yi-Fan; Thiagalingam, Sam; Mez, Jesse; Zhang, Xiaoling; Jun, Gyungah R; Stein, Thor D; Kunkle, Brian W; Martin, Eden R; Pericak-Vance, Margaret A; Mayeux, Richard; Haines, Jonathan L; Schellenberg, Gerard D; Nobrega, Marcelo A; Lunetta, Kathryn L; Pinto, Jayant M; Wang, Li-San; Ober, Carole; Farrer, Lindsay A | Alzheimer's & dementia : the journal of the Alzheimer's Association | 35770850 | 2022 Jun 30 |
| Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates. | Pelletier, Alexandre; Carrier, Arnaud; Zhao, Yongmei; Canouil, Mickaël; Derhourhi, Mehdi; Durand, Emmanuelle; Berberian-Ferrato, Lionel; Greally, John; Hughes, Francine; Froguel, Philippe; Bonnefond, Amélie; Delahaye, Fabien | International journal of molecular sciences | 35806330 | 2022 Jun 30 |
| [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease. | Pascoal, Tharick A; Chamoun, Mira; Lax, Elad; Wey, Hsiao-Ying; Shin, Monica; Ng, Kok Pin; Kang, Min Su; Mathotaarachchi, Sulantha; Benedet, Andrea L; Therriault, Joseph; Lussier, Firoza Z; Schroeder, Frederick A; DuBois, Jonathan M; Hightower, Baileigh G; Gilbert, Tonya M; Zürcher, Nicole R; Wang, Changning; Hopewell, Robert; Chakravarty, Mallar; Savard, Melissa; Thomas, Emilie; Mohaddes, Sara; Farzin, Sarah; Salaciak, Alyssa; Tullo, Stephanie; Cuello, A Claudio; Soucy, Jean-Paul; Massarweh, Gassan; Hwang, Heungsun; Kobayashi, Eliane; Hyman, Bradley T; Dickerson, Bradford C; Guiot, Marie-Christine; Szyf, Moshe; Gauthier, Serge; Hooker, Jacob M; Rosa-Neto, Pedro | Nature communications | 35853847 | 2022 07 19 |
| Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability. | de Mendoza, Alex; Nguyen, Trung Viet; Ford, Ethan; Poppe, Daniel; Buckberry, Sam; Pflueger, Jahnvi; Grimmer, Matthew R; Stolzenburg, Sabine; Bogdanovic, Ozren; Oshlack, Alicia; Farnham, Peggy J; Blancafort, Pilar; Lister, Ryan | Genome biology | 35883107 | 2022 07 26 |
| RNASE6 is a novel modifier of APOE-ε4 effects on cognition. | Seto, Mabel; Weiner, Rebecca L; Dumitrescu, Logan; Mahoney, Emily R; Hansen, Shania L; Janve, Vaibhav; Khan, Omair A; Liu, Dandan; Wang, Yanling; Menon, Vilas; De Jager, Philip L; Schneider, Julie A; Bennett, David A; Gifford, Katherine A; Jefferson, Angela L; Hohman, Timothy J | Neurobiology of aging | 35896049 | 2022 10 |
| Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease. | Thrush, Kyra L; Bennett, David A; Gaiteri, Christopher; Horvath, Steve; Dyck, Christopher H van; Higgins-Chen, Albert T; Levine, Morgan E | Aging | 35907208 | 2022 Jul 30 |
| Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning. | Lahti, Jari; Tuominen, Samuli; Yang, Qiong; Pergola, Giulio; Ahmad, Shahzad; Amin, Najaf; Armstrong, Nicola J; Beiser, Alexa; Bey, Katharina; Bis, Joshua C; Boerwinkle, Eric; Bressler, Jan; Campbell, Archie; Campbell, Harry; Chen, Qiang; Corley, Janie; Cox, Simon R; Davies, Gail; De Jager, Philip L; Derks, Eske M; Faul, Jessica D; Fitzpatrick, Annette L; Fohner, Alison E; Ford, Ian; Fornage, Myriam; Gerring, Zachary; Grabe, Hans J; Grodstein, Francine; Gudnason, Vilmundur; Simonsick, Eleanor; Holliday, Elizabeth G; Joshi, Peter K; Kajantie, Eero; Kaprio, Jaakko; Karell, Pauliina; Kleineidam, Luca; Knol, Maria J; Kochan, Nicole A; Kwok, John B; Leber, Markus; Lam, Max; Lee, Teresa; Li, Shuo; Loukola, Anu; Luck, Tobias; Marioni, Riccardo E; Mather, Karen A; Medland, Sarah; Mirza, Saira S; Nalls, Mike A; Nho, Kwangsik; O'Donnell, Adrienne; Oldmeadow, Christopher; Painter, Jodie; Pattie, Alison; Reppermund, Simone; Risacher, Shannon L; Rose, Richard J; Sadashivaiah, Vijay; Scholz, Markus; Satizabal, Claudia L; Schofield, Peter W; Schraut, Katharina E; Scott, Rodney J; Simino, Jeannette; Smith, Albert V; Smith, Jennifer A; Stott, David J; Surakka, Ida; Teumer, Alexander; Thalamuthu, Anbupalam; Trompet, Stella; Turner, Stephen T; van der Lee, Sven J; Villringer, Arno; Völker, Uwe; Wilson, Robert S; Wittfeld, Katharina; Vuoksimaa, Eero; Xia, Rui; Yaffe, Kristine; Yu, Lei; Zare, Habil; Zhao, Wei; Ames, David; Attia, John; Bennett, David A; Brodaty, Henry; Chasman, Daniel I; Goldman, Aaron L; Hayward, Caroline; Ikram, M Arfan; Jukema, J Wouter; Kardia, Sharon L R; Lencz, Todd; Loeffler, Markus; Mattay, Venkata S; Palotie, Aarno; Psaty, Bruce M; Ramirez, Alfredo; Ridker, Paul M; Riedel-Heller, Steffi G; Sachdev, Perminder S; Saykin, Andrew J; Scherer, Martin; Schofield, Peter R; Sidney, Stephen; Starr, John M; Trollor, Julian; Ulrich, William; Wagner, Michael; Weir, David R; Wilson, James F; Wright, Margaret J; Weinberger, Daniel R; Debette, Stephanie; Eriksson, Johan G; Mosley Jr, Thomas H; Launer, Lenore J; van Duijn, Cornelia M; Deary, Ian J; Seshadri, Sudha; Räikkönen, Katri | Molecular psychiatry | 35974141 | 2022 Nov |
| Risperidone-induced changes in DNA methylation in peripheral blood from first-episode schizophrenia patients parallel changes in neuroimaging and cognitive phenotypes. | Hu, Maolin; Xia, Yan; Zong, Xiaofen; Sweeney, John A; Bishop, Jeffrey R; Liao, Yanhui; Giase, Gina; Li, Bingshan; Rubin, Leah H; Wang, Yunpeng; Li, Zongchang; He, Ying; Chen, Xiaogang; Liu, Chunyu; Chen, Chao; Tang, Jinsong | Psychiatry research | 36075150 | 2022 Nov |
| Integrative Co-methylation Network Analysis Identifies Novel DNA Methylation Signatures and Their Target Genes in Alzheimer's Disease. | Kim, Jun Pyo; Kim, Bo-Hyun; Bice, Paula J; Seo, Sang Won; Bennett, David A; Saykin, Andrew J; Nho, Kwangsik | Biological psychiatry | 36150909 | 2022 Jun 24 |
| Associations between accelerated parental biologic age, autism spectrum disorder, social traits, and developmental and cognitive outcomes in their children. | Song, Ashley Y; Bakulski, Kelly; Feinberg, Jason I; Newschaffer, Craig; Croen, Lisa A; Hertz-Picciotto, Irva; Schmidt, Rebecca J; Farzadegan, Homayoon; Lyall, Kristen; Fallin, M Daniele; Volk, Heather E; Ladd-Acosta, Christine | Autism research : official journal of the International Society for Autism Research | 36189953 | 2022 Dec |
| Effect of APOE alleles on the glial transcriptome in normal aging and Alzheimer's disease. | Serrano-Pozo, Alberto; Li, Zhaozhi; Noori, Ayush; Nguyen, Huong N; Mezlini, Aziz; Li, Liang; Hudry, Eloise; Jackson, Rosemary J; Hyman, Bradley T; Das, Sudeshna | Nature aging | 36199750 | 2021 Oct |
| Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains. | Novotny, Brenna C; Fernandez, Maria Victoria; Wang, Ciyang; Budde, John P; Bergmann, Kristy; Eteleeb, Abdallah M; Bradley, Joseph; Webster, Carol; Ebl, Curtis; Norton, Joanne; Gentsch, Jen; Dube, Umber; Wang, Fengxian; Morris, John C; Bateman, Randall J; Perrin, Richard J; McDade, Eric; Xiong, Chengjie; Chhatwal, Jasmeer; Dominantly Inherited Alzheimer Network (DIAN) Study Group; Alzheimer's Disease Neuroimaging Initiative; and the Alzheimer's Disease Metabolomics Consortium (ADMC); Goate, Alison; Farlow, Martin; Schofield, Peter; Chui, Helena; Karch, Celeste M; Cruchaga, Carlos; Benitez, Bruno A; Harari, Oscar | Alzheimer's & dementia : the journal of the Alzheimer's Association | 36251323 | 2023 May |
| Architecture of the outbred brown fat proteome defines regulators of metabolic physiology. | Xiao, Haopeng; Bozi, Luiz H M; Sun, Yizhi; Riley, Christopher L; Philip, Vivek M; Chen, Mandy; Li, Jiaming; Zhang, Tian; Mills, Evanna L; Emont, Margo P; Sun, Wenfei; Reddy, Anita; Garrity, Ryan; Long, Jiani; Becher, Tobias; Vitas, Laura Potano; Laznik-Bogoslavski, Dina; Ordonez, Martha; Liu, Xinyue; Chen, Xiong; Wang, Yun; Liu, Weihai; Tran, Nhien; Liu, Yitong; Zhang, Yang; Cypess, Aaron M; White, Andrew P; He, Yuchen; Deng, Rebecca; Schöder, Heiko; Paulo, Joao A; Jedrychowski, Mark P; Banks, Alexander S; Tseng, Yu-Hua; Cohen, Paul; Tsai, Linus T; Rosen, Evan D; Klein, Samuel; Chondronikola, Maria; McAllister, Fiona E; Van Bruggen, Nick; Huttlin, Edward L; Spiegelman, Bruce M; Churchill, Gary A; Gygi, Steven P; Chouchani, Edward T | Cell | 36334589 | 2022 Nov 23 |
| Differential Gene Expression and DNA Methylation in the Risk of Depression in LOAD Patients. | Upadhya, Suraj; Gingerich, Daniel; Lutz, Michael William; Chiba-Falek, Ornit | Biomolecules | 36421693 | 2022 Nov 12 |
| Neuroimmune transcriptome changes in patient brains of psychiatric and neurological disorders. | Chen, Yu; Dai, Jiacheng; Tang, Longfei; Mikhailova, Tatiana; Liang, Qiuman; Li, Miao; Zhou, Jiaqi; Kopp, Richard F; Weickert, Cynthia; Chen, Chao; Liu, Chunyu | Molecular psychiatry | 36424395 | 2022 Nov 24 |
| Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment. | Liang, Xiujie; Aranyi, Tamas; Zhou, Jianfu; Guan, Yuting; Hu, Hailong; Liu, Hongbo; Susztak, Katalin | Journal of the American Society of Nephrology : JASN | 36522157 | 2023 Apr 01 |
| Integrated DNA Methylation/RNA Profiling in Middle Temporal Gyrus of Alzheimer's Disease. | Piras, Ignazio S; Brokaw, Danielle; Kong, Yinfei; Weisenberger, Daniel J; Krate, Jonida; Delvaux, Elaine; Mahurkar, Swapna; Blattler, Adam; Siegmund, Kimberly D; Sue, Lucia; Serrano, Geidy E; Beach, Thomas G; Laird, Peter W; Huentelman, Matthew J; Coleman, Paul D | Cellular and molecular neurobiology | 36596913 | 2023 Jul |
| Exploring genes for immunoglobulin A nephropathy: a summary data-based mendelian randomization and FUMA analysis. | Zhang, Qian; Zhang, Kang; Zhu, Yining; Yuan, Guangwei; Yang, Jingyun; Zhang, Minmin | BMC medical genomics | 36709307 | 2023 Jan 29 |
| Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development. | Dhillon, Poonam; Mulholland, Kelly Ann; Hu, Hailong; Park, Jihwan; Sheng, Xin; Abedini, Amin; Liu, Hongbo; Vassalotti, Allison; Wu, Junnan; Susztak, Katalin | Nature communications | 36732547 | 2023 Feb 02 |
| Worsened Outcome in Patients with Membranous Nephropathy Carrying Apolipoprotein L1 High-Risk Genotype. | Susztak, Katalin | Clinical journal of the American Society of Nephrology : CJASN | 36764286 | 2023 Mar 01 |
| Molecular pathways that drive diabetic kidney disease. | Mohandes, Samer; Doke, Tomohito; Hu, Hailong; Mukhi, Dhanunjay; Dhillon, Poonam; Susztak, Katalin | The Journal of clinical investigation | 36787250 | 2023 Feb 15 |
| Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations. | Araujo, Daniel S; Nguyen, Chris; Hu, Xiaowei; Mikhaylova, Anna V; Gignoux, Chris; Ardlie, Kristin; Taylor, Kent D; Durda, Peter; Liu, Yongmei; Papanicolaou, George; Cho, Michael H; Rich, Stephen S; Rotter, Jerome I; NHLBI TOPMed Consortium; Im, Hae Kyung; Manichaikul, Ani; Wheeler, Heather E | bioRxiv : the preprint server for biology | 36798214 | 2023 May 20 |
| Methods for Mediation Analysis with High-Dimensional DNA Methylation Data: Possible Choices and Comparison. | Clark-Boucher, Dylan; Zhou, Xiang; Du, Jiacong; Liu, Yongmei; Needham, Belinda L; Smith, Jennifer A; Mukherjee, Bhramar | medRxiv : the preprint server for health sciences | 36824903 | 2023 Feb 14 |
| Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease. | Seto, Mabel; Dumitrescu, Logan; Mahoney, Emily R; Sclafani, Annah M; De Jager, Philip L; Menon, Vilas; Koran, Mary E I; Robinson, Renã A; Ruderfer, Douglas M; Cox, Nancy J; Seyfried, Nicholas T; Jefferson, Angela L; Schneider, Julie A; Bennett, David A; Petyuk, Vladislav A; Hohman, Timothy J | Neurobiology of aging | 36905877 | 2023 Jun |
| NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury. | Doke, Tomohito; Mukherjee, Sarmistha; Mukhi, Dhanunjay; Dhillon, Poonam; Abedini, Amin; Davis, James G; Chellappa, Karthikeyani; Chen, Beishan; Baur, Joseph A; Susztak, Katalin | Nature metabolism | 36914909 | 2023 Mar |
| HIV viral protein R induces loss of DCT1-type renal tubules. | Latt, Khun Zaw; Yoshida, Teruhiko; Shrivastav, Shashi; Abedini, Amin; Reece, Jeff M; Sun, Zeguo; Lee, Hewang; Okamoto, Koji; Dagur, Pradeep; Heymann, Jurgen; Zhao, Yongmei; Chung, Joon-Yong; Hewitt, Stephen; Jose, Pedro A; Lee, Kyung; He, John Cijiang; Winkler, Cheryl A; Knepper, Mark A; Kino, Tomoshige; Rosenberg, Avi Z; Susztak, Katalin; Kopp, Jeffrey B | bioRxiv : the preprint server for biology | 36945458 | 2023 Nov 13 |
| The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits. | Costanzo, Maria C; von Grotthuss, Marcin; Massung, Jeffrey; Jang, Dongkeun; Caulkins, Lizz; Koesterer, Ryan; Gilbert, Clint; Welch, Ryan P; Kudtarkar, Parul; Hoang, Quy; Boughton, Andrew P; Singh, Preeti; Sun, Ying; Duby, Marc; Moriondo, Annie; Nguyen, Trang; Smadbeck, Patrick; Alexander, Benjamin R; Brandes, MacKenzie; Carmichael, Mary; Dornbos, Peter; Green, Todd; Huellas-Bruskiewicz, Kenneth C; Ji, Yue; Kluge, Alexandria; McMahon, Aoife C; Mercader, Josep M; Ruebenacker, Oliver; Sengupta, Sebanti; Spalding, Dylan; Taliun, Daniel; AMP-T2D Consortium; Smith, Philip; Thomas, Melissa K; Akolkar, Beena; Brosnan, M Julia; Cherkas, Andriy; Chu, Audrey Y; Fauman, Eric B; Fox, Caroline S; Kamphaus, Tania Nayak; Miller, Melissa R; Nguyen, Lynette; Parsa, Afshin; Reilly, Dermot F; Ruetten, Hartmut; Wholley, David; Zaghloul, Norann A; Abecasis, Gonçalo R; Altshuler, David; Keane, Thomas M; McCarthy, Mark I; Gaulton, Kyle J; Florez, Jose C; Boehnke, Michael; Burtt, Noël P; Flannick, Jason | Cell metabolism | 36963395 | 2023 Apr 04 |
| Unbiased Human Kidney Tissue Proteomics Identifies Matrix Metalloproteinase 7 as a Kidney Disease Biomarker. | Hirohama, Daigoro; Abedini, Amin; Moon, Salina; Surapaneni, Aditya; Dillon, Simon T; Vassalotti, Allison; Liu, Hongbo; Doke, Tomohito; Martinez, Victor; Md Dom, Zaipul; Karihaloo, Anil; Palmer, Matthew B; Coresh, Josef; Grams, Morgan E; Niewczas, Monika A; Susztak, Katalin | Journal of the American Society of Nephrology : JASN | 37022120 | 2023 Apr 05 |
| Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution. | Balzer, Michael S; Pavkovic, Mira; Frederick, Julia; Abedini, Amin; Freyberger, Alexius; Vienenkötter, Julia; Mathar, Ilka; Siudak, Krystyna; Eitner, Frank; Sandner, Peter; Grundmann, Manuel; Susztak, Katalin | Cell reports. Medicine | 37023747 | 2023 Apr 18 |
| Epigenetic changes in sperm are associated with paternal and child quantitative autistic traits in an autism-enriched cohort. | Feinberg, Jason I; Schrott, Rose; Ladd-Acosta, Christine; Newschaffer, Craig J; Hertz-Picciotto, Irva; Croen, Lisa A; Daniele Fallin, M; Feinberg, Andrew P; Volk, Heather E | Molecular psychiatry | 37100868 | 2023 Apr 27 |
| Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa. | Rajcsanyi, Luisa S; Hoffmann, Anne; Ghosh, Adhideb; Matrisch-Dinkler, Birgit; Zheng, Yiran; Peters, Triinu; Sun, Wenfei; Dong, Hua; Noé, Falko; Wolfrum, Christian; Herpertz-Dahlmann, Beate; Seitz, Jochen; de Zwaan, Martina; Herzog, Wolfgang; Ehrlich, Stefan; Zipfel, Stephan; Giel, Katrin; Egberts, Karin; Burghardt, Roland; Föcker, Manuel; Tsai, Linus T; Müller, Timo D; Blüher, Matthias; Hebebrand, Johannes; Hirtz, Raphael; Hinney, Anke | Frontiers in genetics | 37101650 | 2023 |
| DNA methylation markers for kidney function and progression of diabetic kidney disease. | Li, Kelly Yichen; Tam, Claudia Ha Ting; Liu, Hongbo; Day, Samantha; Lim, Cadmon King Poo; So, Wing Yee; Huang, Chuiguo; Jiang, Guozhi; Shi, Mai; Lee, Heung Man; TRANSCEND Consortium; Lan, Hui-Yao; Szeto, Cheuk-Chun; Hanson, Robert L; Nelson, Robert G; Susztak, Katalin; Chan, Juliana C N; Yip, Kevin Y; Ma, Ronald C W | Nature communications | 37188670 | 2023 May 15 |
| Mendelian Randomization and Transcriptome-Wide Association Analysis Identified Genes That Were Pleiotropically Associated with Intraocular Pressure. | Yang, Zhikun; Zhang, Zhewei; Zhu, Yining; Yuan, Guangwei; Yang, Jingyun; Yu, Weihong | Genes | 37239387 | 2023 Apr 30 |
| Modeling of mitochondrial genetic polymorphisms reveals induction of heteroplasmy by pleiotropic disease locus 10398A>G. | Smullen, Molly; Olson, Meagan N; Murray, Liam F; Suresh, Madhusoodhanan; Yan, Guang; Dawes, Pepper; Barton, Nathaniel J; Mason, Jivanna N; Zhang, Yucheng; Fernandez-Fontaine, Aria A; Church, George M; Mastroeni, Diego; Wang, Qi; Lim, Elaine T; Chan, Yingleong; Readhead, Benjamin | Scientific reports | 37369829 | 2023 Jun 27 |
| Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer's disease. | Siddiqui, Tohid; Cosacak, Mehmet Ilyas; Popova, Stanislava; Bhattarai, Prabesh; Yilmaz, Elanur; Lee, Annie J; Min, Yuhao; Wang, Xue; Allen, Mariet; İş, Özkan; Atasavum, Zeynep Tansu; Rodriguez-Muela, Natalia; Vardarajan, Badri N; Flaherty, Delaney; Teich, Andrew F; Santa-Maria, Ismael; Freudenberg, Uwe; Werner, Carsten; Tosto, Giuseppe; Mayeux, Richard; Ertekin-Taner, Nilüfer; Kizil, Caghan | NPJ Regenerative medicine | 37429840 | 2023 Jul 10 |
| Pan-primate studies of age and sex. | Horvath, Steve; Haghani, Amin; Zoller, Joseph A; Lu, Ake T; Ernst, Jason; Pellegrini, Matteo; Jasinska, Anna J; Mattison, Julie A; Salmon, Adam B; Raj, Ken; Horvath, Markus; Paul, Kimberly C; Ritz, Beate R; Robeck, Todd R; Spriggs, Maria; Ehmke, Erin E; Jenkins, Susan; Li, Cun; Nathanielsz, Peter W | GeroScience | 37493860 | 2023 Dec |
| Associations of Early-Life Adversity With Later-Life Epigenetic Aging Profiles in the Multi-Ethnic Study of Atherosclerosis. | Schmitz, Lauren L; Duffie, Elizabeth; Zhao, Wei; Ratliff, Scott M; Ding, Jingzhong; Liu, Yongmei; Merkin, Sharon Stein; Smith, Jennifer A; Seeman, Teresa | American journal of epidemiology | 37579321 | 2023 Nov 10 |
| iNETgrate: integrating DNA methylation and gene expression data in a single gene network. | Sajedi, Sogand; Ebrahimi, Ghazal; Roudi, Raheleh; Mehta, Isha; Samimi, Hanie; Kazempour, Shiva; Zainulabadeen, Aamir; Docking, Thomas Roderick; Arora, Sukeshi Patel; Cigarroa, Francisco; Seshadri, Sudha; Karsan, Aly; Zare, Habil | Research square | 37645739 | 2023 Aug 18 |
| ChromGene: gene-based modeling of epigenomic data. | Jaroszewicz, Artur; Ernst, Jason | Genome biology | 37679846 | 2023 Sep 07 |
| Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers. | Karlow, Jennifer A; Pehrsson, Erica C; Xing, Xiaoyun; Watson, Mark; Devarakonda, Siddhartha; Govindan, Ramaswamy; Wang, Ting | Genomics, proteomics & bioinformatics | 37742993 | 2023 Oct |
| The impact of blood MCP-1 levels on Alzheimer's disease with genetic variation of UNC5C and NAV3 loci. | Huang, Jinghan; Wang, Yixuan; Stein, Thor D; Ang, Ting Fang Alvin; Zhu, Yibo; Tao, Qiushan; Lunetta, Kathryn L; Mez, Jesse; Au, Rhoda; Farrer, Lindsay A; Qiu, Wei Qiao; Zhang, Xiaoling | Research square | 37841863 | 2023 Sep 28 |
| Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations. | Araujo, Daniel S; Nguyen, Chris; Hu, Xiaowei; Mikhaylova, Anna V; Gignoux, Chris; Ardlie, Kristin; Taylor, Kent D; Durda, Peter; Liu, Yongmei; Papanicolaou, George; Cho, Michael H; Rich, Stephen S; Rotter, Jerome I; NHLBI TOPMed Consortium; Im, Hae Kyung; Manichaikul, Ani; Wheeler, Heather E | HGG advances | 37869564 | 2023 Oct 12 |
| Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists. | Abedini, Amin; Sánchez-Navaro, Andrea; Wu, Junnan; Klötzer, Konstantin A; Ma, Ziyuan; Poudel, Bibek; Doke, Tomohito; Balzer, Michael S; Frederick, Julia; Cernecka, Hana; Liu, Hongbo; Liang, Xiujie; Vitale, Steven; Kolkhof, Peter; Susztak, Katalin | The Journal of clinical investigation | 37906287 | 2024 Jan 02 |
| Methods for mediation analysis with high-dimensional DNA methylation data: Possible choices and comparisons. | Clark-Boucher, Dylan; Zhou, Xiang; Du, Jiacong; Liu, Yongmei; Needham, Belinda L; Smith, Jennifer A; Mukherjee, Bhramar | PLoS genetics | 37934796 | 2023 Nov |
| Sex-specific genetic architecture of late-life memory performance. | Eissman, Jaclyn M; Archer, Derek B; Mukherjee, Shubhabrata; Lee, Michael L; Choi, Seo-Eun; Scollard, Phoebe; Trittschuh, Emily H; Mez, Jesse B; Bush, William S; Kunkle, Brian W; Naj, Adam C; Gifford, Katherine A; Alzheimer's Disease Neuroimaging Initiative (ADNI) | Alzheimer's Disease Genetics Consortium (ADGC) | The Alzheimer's Disease Sequencing Project (ADSP); Cuccaro, Michael L; Cruchaga, Carlos; Pericak-Vance, Margaret A; Farrer, Lindsay A; Wang, Li-San; Schellenberg, Gerard D; Mayeux, Richard P; Haines, Jonathan L; Jefferson, Angela L; Kukull, Walter A; Keene, C Dirk; Saykin, Andrew J; Thompson, Paul M; Martin, Eden R; Bennett, David A; Barnes, Lisa L; Schneider, Julie A; Crane, Paul K; Hohman, Timothy J; Dumitrescu, Logan | Alzheimer's & dementia : the journal of the Alzheimer's Association | 37984853 | 2024 Feb |
| Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease. | Archer, Derek B; Eissman, Jaclyn M; Mukherjee, Shubhabrata; Lee, Michael L; Choi, Seo-Eun; Scollard, Phoebe; Trittschuh, Emily H; Mez, Jesse B; Bush, William S; Kunkle, Brian W; Naj, Adam C; Gifford, Katherine A; Alzheimer's Disease Neuroimaging Initiative (ADNI); Alzheimer's Disease Genetics Consortium (ADGC); Alzheimer's Disease Sequencing Project (ADSP); Cuccaro, Michael L; Pericak-Vance, Margaret A; Farrer, Lindsay A; Wang, Li-San; Schellenberg, Gerard D; Mayeux, Richard P; Haines, Jonathan L; Jefferson, Angela L; Kukull, Walter A; Keene, C Dirk; Saykin, Andrew J; Thompson, Paul M; Martin, Eden R; Bennett, David A; Barnes, Lisa L; Schneider, Julie A; Crane, Paul K; Dumitrescu, Logan; Hohman, Timothy J | Alzheimer's & dementia : the journal of the Alzheimer's Association | 37985223 | 2024 Feb |
| Polygenic burden of short tandem repeat expansions promote risk for Alzheimer's disease. | Guo, Michael H; Lee, Wan-Ping; Vardarajan, Badri; Schellenberg, Gerard D; Phillips-Cremins, Jennifer | medRxiv : the preprint server for health sciences | 38014121 | 2023 Nov 16 |
| Combing Genome-Wide Association Studies and Single-Cell Analysis to Elucidate the Mechanisms of Kidney Disease: Proceedings of the Henry Shavelle Professorship. | Levinsohn, Jonathan; Li, Shen; Ha, Eunji; Susztak, Katalin | Glomerular diseases | 38033715 | 2023 |
| ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules. | Mukhi, Dhanunjay; Li, Lingzhi; Liu, Hongbo; Doke, Tomohito; Kolligundla, Lakshmi P; Ha, Eunji; Kloetzer, Konstantin; Abedini, Amin; Mukherjee, Sarmistha; Wu, Junnan; Dhillon, Poonam; Hu, Hailong; Guan, Dongyin; Funai, Katsuhiko; Uehara, Kahealani; Titchenell, Paul M; Baur, Joseph A; Wellen, Kathryn E; Susztak, Katalin | The Journal of clinical investigation | 38051585 | 2023 Dec 05 |
| Integrating DNA methylation and gene expression data in a single gene network using the iNETgrate package. | Sajedi, Sogand; Ebrahimi, Ghazal; Roudi, Raheleh; Mehta, Isha; Heshmat, Amirreza; Samimi, Hanie; Kazempour, Shiva; Zainulabadeen, Aamir; Docking, Thomas Roderick; Arora, Sukeshi Patel; Cigarroa, Francisco; Seshadri, Sudha; Karsan, Aly; Zare, Habil | Scientific reports | 38066050 | 2023 Dec 08 |
| An epigenome-wide analysis of DNA methylation, racialized and economic inequities, and air pollution. | Watkins, Sarah Holmes; Testa, Christian; Simpkin, Andrew J; Smith, George Davey; Coull, Brent; De Vivo, Immaculata; Tilling, Kate; Waterman, Pamela D; Chen, Jarvis T; Diez-Roux, Ana V; Krieger, Nancy; Suderman, Matthew; Relton, Caroline | bioRxiv : the preprint server for biology | 38105971 | 2023 Dec 08 |
| Epigenetic aging & embodying injustice: US My Body My Story and Multi-Ethnic Atherosclerosis Study. | Krieger, Nancy; Testa, Christian; Chen, Jarvis T; Johnson, Nykesha; Watkins, Sarah H; Suderman, Matthew; Simpkin, Andrew J; Tilling, Kate; Waterman, Pamela D; Coull, Brent A; De Vivo, Immaculata; Smith, George Davey; Roux, Ana V Diez; Relton, Caroline | medRxiv : the preprint server for health sciences | 38168159 | 2023 Dec 14 |
| Metabolomics profiling reveals distinct, sex-specific signatures in the serum and brain metabolomes in the mouse models of Alzheimer's disease. | Pandey, Ravi S; Arnold, Mattias; Batra, Richa; Krumsiek, Jan; Kotredes, Kevin P; Garceau, Dylan; Williams, Harriet; Sasner, Michael; Howell, Gareth R; Kaddurah-Daouk, Rima; Carter, Gregory W | bioRxiv : the preprint server for biology | 38187571 | 2023 Dec 22 |
| Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model. | Martin Flores, Nuria; Podpolny, Marina; McLeod, Faye; Workman, Isaac; Crawford, Karen; Ivanov, Dobril; Leonenko, Ganna; Escott-Price, Valentina; Salinas, Patricia C | eLife | 38285009 | 2024 Jan 29 |
| Unraveling the epigenetic code: human kidney DNA methylation and chromatin dynamics in renal disease development. | Yan, Yu; Liu, Hongbo; Abedini, Amin; Sheng, Xin; Palmer, Matthew; Li, Hongzhe; Susztak, Katalin | Nature communications | 38287030 | 2024 Jan 29 |
| Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease. | Arnold, Matthias; Buyukozkan, Mustafa; Doraiswamy, P Murali; Nho, Kwangsik; Wu, Tong; Gudnason, Vilmundur; Launer, Lenore J; Wang-Sattler, Rui; Adamski, Jerzy; Alzheimer’s Disease Neuroimaging Initiative; Alzheimer’s Disease Metabolomics Consortium; De Jager, Philip L; Ertekin-Taner, Nilüfer; Bennett, David A; Saykin, Andrew J; Peters, Annette; Suhre, Karsten; Kaddurah-Daouk, Rima; Kastenmüller, Gabi; Krumsiek, Jan | medRxiv : the preprint server for health sciences | 38313266 | 2024 Jan 24 |
| APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response. | Panitch, Rebecca; Sahelijo, Nathan; Hu, Junming; Nho, Kwangsik; Bennett, David A; Lunetta, Kathryn L; Au, Rhoda; Stein, Thor D; Farrer, Lindsay A; Jun, Gyungah R | Translational psychiatry | 38424036 | 2024 Feb 29 |
| Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing. | Rohm, Dahlia; Black, Joshua B; McCutcheon, Sean R; Barrera, Alejandro; Morone, Daniel J; Nuttle, Xander; de Esch, Celine E; Tai, Derek J C; Talkowski, Michael E; Iglesias, Nahid; Gersbach, Charles A | bioRxiv : the preprint server for biology | 38496583 | 2024 Mar 04 |
