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Funded Research

The Epigenomics program has transitioned from Common Fund support. For more information, please visit https://commonfund.nih.gov/epigenomics.

Please note that since the Epigenomics program is no longer supported by the Common Fund, the program website is being maintained as an archive and will not be updated on a regular basis.

 

NIH Support for Conferences and Scientific Meetings (Parent R13/U13) PA-13-347
PI NameInstitution NameTitle
STAMATOYANNOPOULOS, JOHN A (contact)
MILOSAVLJEVIC, ALEKSANDAR
UNIVERSITY OF WASHINGTONEpigenomics 2015: A Roadmap to the Living Genome
WOODLAND, DAVID L.KEYSTONE SYMPOSIADNA Methylation
WOODLAND, DAVID L.KEYSTONE SYMPOSIAEpigenomics

 

Computational Analyses Exploiting Reference Epigenomic Maps (R01) RFA-RM-14-001
PI NameInstitution NameTitle
FUREY, TERRENCE S. (contact)
SHEIKH, SHEHZAD Z.
UNIV OF NORTH CAROLINA CHAPEL HILLInterpreting molecular role of DNA variants associated with Crohns Disease through integrative analysis of open chromatin, epigenome and transcriptome data in diverse and relevant tissues and cells
INCE, TAN A.UNIVERSITY OF MIAMIComputational and Biological Deconvolution of Epigenomic Datasets
JOHNSON, WILLIAM EVANBOSTON UNIVERSITY MEDICAL CAMPUSIntegrative analyses of reference epigenomic maps and applications
LI, ZHAOYU (contact)
ASMANN, YAN W.
MAYO CLINIC JACKSONVILLEBuilding the Foundation of Epigenomics Roadmaps
LIU, CHUNYUUNIVERSITY OF ILLINOIS AT CHICAGOIntegrating epigenomic maps to predict regulatory functions of genetic variants
NOBLE, WILLIAM STAFFORDUNIVERSITY OF WASHINGTONMachine learning methods to impute and annotate epigenomic maps
PRITCHARD, JONATHAN KSTANFORD UNIVERSITYComputational methods for modeling lineage-specific gene regulation
REN, BINGLUDWIG INSTITUTE  FOR CANCER RES  LTDIntegrative Analysis of Haplotype-Resolved Human Epigenome Maps
WAGERS, AMY JOHARVARD UNIVERSITYEpigenomic drivers of human muscle progenitor cells in development and disease
WANG, TINGWASHINGTON UNIVERSITYCHARTING THE EPIGENOMIC LANDSCAPE OF HUMAN TRANSPOSABLE ELEMENTS
XING, YI (contact)
HOFFMANN, ALEXANDER
UNIVERSITY OF CALIFORNIA LOS ANGELESEpigenomic control of RNA splicing

 

Functional Epigenomics: Developing Tools and Technologies for Cell-type, Temporal, or Locus-specific Manipulation of the Epigenome (R01) RFA-RM-12-026
PI NameInstitution NameTitle
BLANCAFORT, PILAR (contact)
LISTER, RYAN
UNIVERSITY OF WESTERN AUSTRALIAPrecision engineering of DNA methylation patterns in the human genome
DURONIO, ROBERT J (contact)
MATERA, A. GREGORY
STRAHL, BRIAN D
UNIV OF NORTH CAROLINA CHAPEL HILLEngineering histone genes to interrogate the epigenetic code in space and time
GERSBACH, CHARLES A (contact)
CRAWFORD, GREGORY E
DUKE UNIVERSITYEngineering Targeted Epigenetic Modifiers for Precise Control of Gene Regulation
KOIDE, SHOHEIUNIVERSITY OF CHICAGOGenetically encoded designer inhibitors for functional epigenomics
KUHLMAN, BRIAN A (contact)
HAHN, KLAUS MICHAEL
UNIV OF NORTH CAROLINA CHAPEL HILLSpatiotemporal Control of the Epigenome via Photoactivatable Nuclear Localization
LEE, JEANNIE TMASSACHUSETTS GENERAL HOSPThe RNA-activation platform to treat X-linked disease in a locus-specific manner
LOMVARDAS, STAVROS (contact)
BARNEA, GILAD
UNIVERSITY OF CALIFORNIA SAN FRANCISCOControlling epigenetic states and nuclear architecture in the brain
MEISSNER, ALEXANDERHARVARD UNIVERSITYGeneration and characterization of tools for target-specific de novo DNA methylat
TASIC, BOSILJKA (contact)
MADISEN, LINDA
ALLEN INSTITUTE FOR BRAIN SCIENCETemporal, cell type- and locus-specific epigenetic control in transgenic mice
WEISSMAN, JONATHAN S. (contact)
LIM, WENDELL A
QI, LEI STANLEY
UNIVERSITY OF CALIFORNIA SAN FRANCISCOHarnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming

 

Epigenomics of Human Health and Disease (R01) RFA-RM-08-017
PI NameInstitution NameTitle
BENNETT, DAVID A.RUSH UNIVERSITY MEDICAL CENTERExploring the Role of the Brain Epigenome: Cognitive Decline and Life Experiences
COLEMAN, PAUL D.SUN HEALTH RESEARCH INSTITUTEDNA methylation in Alzheimer's disease and normally aged brain
CONNELLY, JESSICA J.UNIVERSITY OF VIRGINIA CHARLOTTESVILLEEpigenomics of Atherosclerosis
EINSTEIN, FRANCINE HUGHES (contact)
GREALLY, JOHN
MONTAGNA, CRISTINA
YESHIVA UNIVERSITYGenome-wide DNA Methylation Profiles Associated with Abnormal Intrauterine Growth
FALLIN, MARGARET DANIELE (Contact)
FEINBERG, ANDREW P.
JOHNS HOPKINS UNIVERSITYEnvironment, The Perinatal Epigenome, and Risk for Autism and Related Disorders
GIBBONS, GARY HUGHMOREHOUSE SCHOOL OF MEDICINEVascular Epigenome Dynamics in African-American Hypertensives
HUANG, TIM H.-M.OHIO STATE UNIVERSITYEpigenomics of Bisphenol A Exposure and Disease Risk
KOHWI-SHIGEMATSU, TERUMIUNIVERSITY OF CALIF-LAWRENC BERKELEY LABDeterminants for genome-wide epigenomics in metastatic breast cancer
LIU, YONGMEIWAKE FOREST UNIVERSITY HEALTH SCIENCESEpigenome-Wide Association Study of DNA Methylation and Atherosclerosis
MELTZER, STEPHEN J.JOHNS HOPKINS UNIVERSITYThe temporal epigenomic program of Barrett's neoplastic progression
MERBS, SHANNATH L.JOHNS HOPKINS UNIVERSITYPangenomic Analysis of DNA Methylation Marks in Glaucoma and Macular Degeneration
MILL, JONATHANKING'S COLLEGE LONDONA multi-faceted approach to epigenomic profiling in Alzheimer's disorder
OPHOFF, ROEL A.UNIVERSITY OF CALIFORNIA LOS ANGELESEpigenetics and disease: the role of DNA methylation in schizophrenia susceptibility
PETRONIS, ARTCENTRE FOR ADDICTION AND MENTAL HEALTHDNA METHYLOME ANALYSIS IN BIPOLAR DISORDER
PFEIFER, GERD P.CITY OF HOPE/BECKMAN RESEARCH INSTITUTEAging and the unstable epigenome
ROSEN, EVAN D.BETH ISRAEL DEACONESS MEDICAL CENTEREpigenomics of Human Insulin Resistance
SCHWARTZ, DAVID ALBERT (contact)
COSGROVE, GREGORY P.
YANG, IVANA VERONA
NATIONAL JEWISH HEALTHAsthma: An Epidemic Caused by Epigenetics?
SULLIVAN, KATHLEEN E.CHILDREN'S HOSPITAL OF PHILADELPHIAEpigenomics of SLE
SUSZTAK, KATALIN (contact)
GREALLY, JOHN
YESHIVA UNIVERSITYEpigenetics Landscape of Chronic Kidney Disease
TYCKO, BENJAMIN (contact)
MAYEUX, RICHARD
COLUMBIA UNIVERSITY HEALTH SCIENCESEpigenomics of Alzheimer's Disease
YOKOMORI, KYOKOUNIVERSITY OF CALIFORNIA IRVINEEpigenomic Analysis of Facioscapulohumeral Muscular Dystrophy
YOUNG, RICHARDWHITEHEAD INSTITUTE FOR BIOMEDICAL RESEpigenomic Mapping in Human Tumor Stem Cells

 

Reference Epigenome Mapping Centers (U01) RFA-RM-07-013 
PI NameInstitution NameTitle
BERNSTEIN, BRADLEY E (contact)
MEISSNER, ALEXANDER
MASSACHUSETTS INSTITUTE OF TECHNOLOGYProduction sequencing of reference human epigenomes
COSTELLO, JOSEPH F (contact)
MARRA, MARCO ANTONIO
UNIVERSITY OF CALIFORNIA SAN FRANCISCOIntegrated Epigenetic Maps of Human Embryonic and Adult Cells
REN, BINGLUDWIG INSTITUTE FOR CANCER RESEARCHThe San Diego Epigenome Center
STAMATOYANNOPOULOS, JOHNUNIVERSITY OF WASHINGTONNorthwest Reference Epigenome Mapping Center

 

Epigenomics Data Analysis and Coordination Center - EDACC (U01) RFA-RM-07-014     
PI NameInstitution NameTitle
BEAUDET, ARTHUR L.
MILOSAVLJEVIC, ALEKSANDAR (contact)
BAYLOR COLLEGE OF MEDICINEEpigenomics Data Analysis and Coordination Center at Baylor College of Medicine

 

Developing Technologies for Improved In Vivo Epigenetic Imaging or Analysis (R01) RFA-RM-09-016     
PI NameInstitution NameTitle
GELOVANI, JURI GUNIVERSITY OF TEXAS MD ANDERSON CAN CTRNovel HDAC Class III Specific Radiotracers for PET Imaging
GREALLY, JOHN (contact)
LEVY, MATTHEW
ALBERT EINSTEIN COL OF MED YESHIVA UNIVIn vivo imaging of X inactivation
HENIKOFF, STEVENFRED HUTCHINSON CANCER RESEARCH CENTEREpigenomic profiling of histone turnover kinetics in mammalian cells
HOOKER, JACOB MMASSACHUSETTS GENERAL HOSPITALDesign of Class-specific HDAC Imaging Probes for Positron Emission Tomography
KERPPOLA, TOMUNIVERSITY OF MICHIGAN AT ANN ARBORVisualization of Combinatorial Epigenetic Marks and Complexes in Animals Using Fl
LAIRD, PETER WUNIVERSITY OF SOUTHERN CALIFORNIAVisualizing the effect of epigenetic modifications on transcription and mutation
LIS, JOHN THOMAS (contact)
CRAIGHEAD, HAROLD G
ZIPFEL, WARREN R 
LIN, HENING
CORNELL UNIVERSITY ITHACAIn vivo Detection and Imaging of Epigenetic Histone Modifications and Modifying E
LOMVARDAS, STAVROS (contact) 
LARABELL, CAROLYN A
UNIVERSITY OF CALIFORNIA SAN FRANCISCODevising New Technologies for Live Imaging of Epigenetic Processes
YOUNG, WON-BIN (contact) 
AHRENS, ERIC T
CARNEGIE-MELLON UNIVERSITYIn Vivo Visualization and Quantification of Epigenetic Activities Using Magnetic

 

Technology Development in Epigenetics (R21) RFA-RM-07-012   
PI NameInstitution NameTitle
GOZANI, OR P. (Contact) 
BEDFORD, MARK T
STANFORD UNIVERSITYApplying peptide and protein domain microarrays to epigenetic research
HANG, HOWARD CROCKEFELLER UNIVERSITYChemical Reporters for the Analysis of Lysine Methylation in Epigenetics
HENIKOFF, STEVENFRED HUTCHINSON CANCER RESEARCH CENTERGenome-wide measurement of histone replacement rates: a new dimension in epigenom
KOIDE, SHOHEIUNIVERSITY OF CHICAGONovel affinity reagents for epigenetics markers
LIU, RIHEUNIVERSITY OF NORTH CAROLINA CHAPEL HILLIdentification of the Interactome of Methylated Histones from Human Proteome

 

Technology Development in Epigenetics (R01) RFA-RM-07-011  
PI NameInstitution NameTitle
CRAIGHEAD, HAROLD G 
SOLOWAY, PAUL D (contact)
CORNELL UNIVERSITY ITHACAEpigenomic analysis on a nanoscale device
MITRA, ROBI DWASHINGTON UNIVERSITYMETHYLMAP: A TECHNOLOGY TO ANALYZE PROMOTER METHYLATION IN MICRODISSECTED CELLS
ZHANG, KUN (Contact) 
SHI, HUIDONG
UNIVERSITY OF CALIFORNIA SAN DIEGOGenome-scale anaylsis of DNA methylation in CpG Islands with bisulfite sequencing
TACKETT, ALAN (Contact) 
TAVERNA, SEAN D.
UNIVERSITY OF ARKANSAS MED SCIS LTL ROCKDevelopment of technology for high resolution epigenetic profiling of chromatin

 

Discovery of Novel Epigenetic Marks in Mammalian Cells (R21) RFA-RM-07-016   
PI NameInstitution NameTitle
CHEN, XIAN 
STRAHL, BRIAN D (contact)
UNIVERSITY OF NORTH CAROLINA CHAPEL HILLIdentification of novel histone modifications in a model eukaryote
WARBURTON, PETER EMOUNT SINAI SCHOOL OF MEDICINE OF NYUNon-coding RNAs in the epigenetics of human centromere formation

 

Discovery of Novel Epigenetic Marks in Mammalian Cells (R01) RFA-RM-07-015   
PI NameInstitution NameTitle
CHENG, XIAODONGEMORY UNIVERSITYIdentification and characterization of novel epigenetic marks of non-histone prot
GRANT, PATRICK AUNIVERSITY OF VIRGINIA CHARLOTTESVILLECharacterization of a novel histone H3 phosphorylation mark in DNA replication
KATZ, RICHARD ALANINSTITUTE FOR CANCER RESEARCHDiscovery of Epigenetic Marks in Human Cells by High Throughput siRNA Screening
OETTINGER, MARJORIE AMASSACHUSETTS GENERAL HOSPITALIs symmetrical dimethylation of Arginine 2 of Histone H3 used as an epigenetic si
TULIN, ALEXEI V 
ZARET, KENNETH S (contact)
INSTITUTE FOR CANCER RESEARCHNovel Epigenetic Marks in Mitosis
ZHAO, YINGMINGUNIVERSITY OF TEXAS SW MED CTR/DALLASSystematic screening for new histone marks

This page last reviewed on January 30, 2024