​​The NIH Common Fund and the American Recovery and Reinvestment Act (ARRA)

FUNDED RESEARCH

Common Fund Awards $38.4M in ARRA Funds in Fiscal Year 2010

During fiscal year 2010 (October 1, 2009 - September 30, 2010) the NIH Common Fund made nine new American Recovery and Reinvestment Act (ARRA) awards totaling $38.4M. These programs of research are unique and highly innovative, and have the potential to dramatically accelerate discovery in biomedicine and development of new treatments for myriad diseases and disorders. For example, Thomas Grabowski (University of Washington) and colleagues are using new systems neuroimaging approaches to investigate age-related cognitive decline, neurodegenerative diseases (including Alzheimer disease and Parkinson's disease), and rehabilitation of paralysis using brain-computer interfaces (1RC4NS073008-01). In contrast, Mitchell Kronenberg (La Jolla Institute for Allergy and Immunology) and colleagues are constructing a screening facility that provides the " libraries" of molecular reagents and instrumentation needed to conduct large-scale investigations of how the body fights off infectious and autoimmune diseases and cancers (1RC4AI092763-01). In another highly innovative program of research, Cameron Currie (University of Wisconsin - Madison) and colleagues are using "high-throughput screening" and mouse models of disease to first identify and then evaluate the anti-infective potential of small molecules derived from untapped sources of natural products (1RC4GM096347-01).

On this page:

• RFA-OD-10-005: Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4)
• RFA-0D-09-003: NIH Challenge Grants in Health and Science Research (RC1)
• RFA-OD-09-004: Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure “Grand Opportunities” (RC2)
• NOT-OD-09-060: Administrative Supplements Providing Summer Research Experiences
• NOT-OD-09-058: Recovery Act Limited Competition for Revision Applications
• NOT-OD-09-056: Recovery Act Funds for Administrative Supplements
• RFA-RM-09-003: 2009 NIH Director's New Innovator Award Program (DP2)
• RFA-RM-07-012: Technology Development in Epigenetics (R21)
• RFA-RM-07-015: Discovery of Novel Epigenetic Marks in Mammalian Cells (R01)
• RFA-RM-07-016: Discovery of Novel Epigenetic Marks in Mammalian Cells (R21)
• RFA-RM-08-001: Construction of a Reference Sequence Data Set for the Human Microbiome Project (U54)
• RFA-RM-08-023: Patient-Reported Outcomes Measurement Information System^TM (PROMIS) Research Sites (U01)
• RFA-RM-08-025: Patient-Reported Outcomes Measurement Information System^TM (PROMIS) Statistical Center (U54)

PI Name	Institution Name	Title
RFA-OD-10-005: Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4)
CURRIE, CAMERON ROBERT	UNIVERSITY OF WISCONSIN MADISON	Discovery of natural product-based drugs from bacterial symbionts of insects
GRABOWSKI, THOMAS J.	UNIVERSITY OF WASHINGTON	IBIC: Integrated Brain Imaging Center for the University of Washington
KIRSCHNER, MARC WALLACE	HARVARD UNIVERSITY (MEDICAL SCHOOL)	Quantifying post-translational modifications and protein expression by HTP-MS
KRONENBERG, MITCHELL	LA JOLLA INST FOR ALLERGY & IMMUNOLGY	New players in immune function: identification through RNAi and micro-RNA screens
SPIEGELMAN, BRUCE M.	DANA-FARBER CANCER INSTITUTE	Regulation of Brown Fat: Toward New Therapy for Human Obesity
SUTCLIFFE, JULIE L	UNIVERSITY OF CALIFORNIA DAVIS	High throughput design, synthesis and in vivo evaluation of targeted molecular im
VIDAL, MARC	DANA-FARBER CANCER INSTITUTE	Generation and validation of a comprehensive human disease mutant ORF resource
WEIR, DAVID R.	UNIVERSITY OF MICHIGAN AT ANN ARBOR	Expanding a National Resource for Genetic Research in Behavioral & Health Science
WERNIG, MARIUS	STANFORD UNIVERSITY	Dissecting the mechanism of direct neural induction through genomic interrogation

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PI Name	Institution Name	Title
RFA-0D-09-003: NIH Challenge Grants in Health and Science Research (RC1)
Science, Technology, Engineering and Mathematics (S.T.E.M.) Education Common Fund Challenge Awards
BAO, LEI	OHIO STATE UNIVERSITY	This award is funded through the American Recovery and Reinvestment Act
BOTTOMLEY, LAURA JONES (contact);  LAVELLE, JEROME	NORTH CAROLINA STATE UNIVERSITY RALEIGH	Do Engineering Curricula Improve Science and Mathematics Learning in Elementary S
GOLINKOFF, ROBERTA MICHNICK	UNIVERSITY OF DELAWARE	Shape Up Preschoolers Geometric Sense Predicts Future Mathematics Achievement
GRISSMER, DAVID W.	UNIVERSITY OF VIRGINIA CHARLOTTESVILLE	Improving Fine Motor Skill Development to Promote Mathematical Ability
HURTADO, SYLVIA	UNIVERSITY OF CALIFORNIA LOS ANGELES	Introductory S.T.E.M. Courses: Sorting, Harvesting, or Nurturing Student Talent
JITENDRA, ASHA KIRON	UNIVERSITY OF MINNESOTA TWIN CITIES	Improving Problem-Solving Performance of Students with Mathematics Difficulties
KELLMAN, PHILIP J	UNIVERSITY OF CALIFORNIA LOS ANGELES	Using Perceptual and Adaptive Learning to Advance Chemistry Education
PIASTA, SHAYNE B.	OHIO STATE UNIVERSITY	Efficacy of the Core Knowledge Approach to Math and Science Preschool Instruction
PRITCHARD, DAVID E	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	Integrating and Evaluating the Modeling Applied to Problem Solving Pedagogy
SADLER, PHILIP MICHAEL	HARVARD UNIVERSITY	ALSISE: Assessment of Life Science Intermediate School Educators
SHAPIRO, JENESSA	UNIVERSITY OF CALIFORNIA LOS ANGELES	Reducing Barriers to Gender Equity in S.T.E.M. Fields by Reducing Stereotype Threats
SHEPHERD, VIRGINIA L	VANDERBILT UNIVERSITY	Evaluation of the Impact of a Sustained Scientist-in-the-Classroom Program
WENDELL, DOUGLAS L (contact) PICKARD, DAWN M.	OAKLAND UNIVERSITY	DNA Markers for Fast Plants to Teach Scientific Thinking
Other Common Fund Challenge Awards
CHEN, LIN (contact); PETASIS, NICOS A	UNIVERSITY OF SOUTHERN CALIFORNIA	Mechanism-based small molecule epigenetic modulators: Targeting specific HDACs
COOK, KARON FRANCES	UNIVERSITY OF WASHINGTON	Development and Validation of Measures of Pain Behaviors in Chronic Pain
FRYE, STEPHEN VERNON	UNIVERSITY OF NORTH CAROLINA CHAPEL HILL	Discovery of Small Molecule MBT Domain Antagonists
KOIDE, SHOHEI	UNIVERSITY OF CHICAGO	Renewable synthetic antibodies for epigenomics
MCMURRAY, CYNTHIA THERESE (contact); NORTHEN, TRENT R.	UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB	MT Function and Dysfunction in Single Neurons in Vivo
PRELICH, GREGORY	ALBERT EINSTEIN COL OF MED YESHIVA UNIV	Identification of Small Molecule Inhibitors of SUMOylation
VUORI, KRISTIINA	BURNHAM INSTITUTE FOR MEDICAL RESEARCH	High throughput screening in human 3D spheroids of epithelial, endothelial, and s
WANSINK, BRIAN	CORNELL UNIVERSITY ITHACA	Nudging Nutrition: Setting Healthier Defaults in Stores and in Homes
ZHOU, MING-MING (contact) WALSH, MARTIN JOHN	MOUNT SINAI SCHOOL OF MEDICINE OF NYU	A Novel Epigenetic Gene Silencing Technology

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PI Name	Institution Name	Title
RFA-OD-09-004: Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure "Grand Opportunities"; (RC2)
ABRAMSON, STEVEN B (contact);  LITTMAN, DAN R.	NEW YORK UNIVERSITY SCHOOL OF MEDICINE	Role of oral and intestinal microbiota in Rheumatoid Arthritis
BUCHWALD, DEDRA S.	UNIVERSITY OF WASHINGTON	Building a Unique National Community Based Twin Repository
COOKE, JOHN P.	STANFORD UNIVERSITY	NCE-based strategy for nuclear reprogramming and regenerative medicine
CRITSER, JOHN K.	UNIVERSITY OF MISSOURI-COLUMBIA	Development of humanized models using human induced pluripotent stem cells
FOX, GEOFFREY C.	INDIANA UNIVERSITY BLOOMINGTON	Investigation of Cloud Computing to Support Data-Parallel Health Research
KHARRAZI, MARTIN	SEQUOIA FOUNDATION	Development of a Research-Ready Pregnancy and Newborn Biobank in California
LARK, MICHAEL WILLIAM	TREVENA, INC.	Selective modulation of GPCR signal transduction with biased ligands
MEURICE, NATHALIE (contact);  HULME, CHRISTOPHER ;  MOUSSES, SPYRO	TRANSLATIONAL GENOMICS RESEARCH INST	The Southwest Comprehensive Center for Drug Discovery and Development
MORITZ, ROBERT L (contact); HOOD, LEROY E.	INSTITUTE FOR SYS.T.E.M.S BIOLOGY	Complete Human Peptide- and MRM-Atlas
MOSKOWITZ, JAY	UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA	An Open Source Research Permissions Framework for South Carolina
VOLPP, KEVIN G (contact); ASCH, DAVID A.	UNIVERSITY OF PENNSYLVANIA	Developing Interactive Technologies to Improve Research and Health Behavior

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PI Name	Institution Name	Title
NOT-OD-09-060: Administrative Supplements Providing Summer Research Experiences
CHRISTMAN, KAREN L	UNIVERSITY OF CALIFORNIA SAN DIEGO	Engineering a Dynamic Extracellular Matrix Microenvironment
SHERLEY, JAMES L	BOSTON BIOMEDICAL RESEARCH INSTITUTE	NIH Director's Pioneer Award
TOOMRE, DEREK K.	YALE UNIVERSITY	Novel TIRF microscopy analyzing trafficking & signaling at the cell cortex

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PI Name	Institution Name	Title
NOT-OD-09-058: Recovery Act Limited Competition for Revision Applications
FIDOCK, DAVID ARMAND	COLUMBIA UNIVERSITY HEALTH SCIENCES	A Cell-based HTS for Delayed Death Inhibitors of the Malarial Parasite Plastid

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PI Name	Institution Name	Title
NOT-OD-09-056: Recovery Act Funds for Administrative Supplements
GOZANI, OR P. (contact); BEDFORD, MARK T.	STANFORD UNIVERSITY	Applying peptide and protein domain microarrays to epigenetic research
KIKINIS, RON	BRIGHAM AND WOMEN'S HOSPITAL	National Alliance-Medical Imaging Computing (NAMIC)(RMI)
KNIGHT, ROBIN	UNIVERSITY OF COLORADO AT BOULDER	New Tools for Understanding the Composition and Dynamics of Microbial Communities
WHITE, OWEN R	UNIVERSITY OF MARYLAND BALTIMORE	A Quality Assurance, Coordination and Analysis Center for HMP

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PI Name	Institution Name	Title
RFA-RM-09-003: 2009 NIH Director's New Innovator Award Program (DP2)
BANERJEE, IPSITA	UNIVERSITY OF PITTSBURGH AT PITTSBURGH	Defining Mechanisms Controlling Stem Cell Fate During Differentiation
CAMARGO, FERNANDO	CHILDREN'S HOSPITAL BOSTON	Analysis Of Stem Cell Dynamics And Differentiation By Cellular Barcoding
CHRONIS, NIKOLAOS	UNIVERSITY OF MICHIGAN AT ANN ARBOR	A Biochip For Point-Of-Care Hiv/Aids Diagnosis In The Developing World
ORDWAY, DIANE JOYCE	COLORADO STATE UNIVERSITY-FORT COLLINS	Immune Modulation By Highly Virulent Clinical Isolates Of M.Tuberculosis
SONNENBURG, JUSTIN	STANFORD UNIVERSITY	Discovery of gut microbiota-targeted small molecules: new tools and therapeutics
TAVAZOIE, SOHAIL F	ROCKEFELLER UNIVERSITY	The discovery of microRNAs that predict chemotherapeutic responsiveness of cancer
WEINBERGER, LEOR S	UNIVERSITY OF CALIFORNIA SAN DIEGO	Developing Transmissible Antivirals by Exploiting Gene-Expression Circuitry

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PI Name	Institution Name	Title
RFA-RM-07-012: Technology Development in Epigenetics (R21)
JAFFE, JACOB DAVID	BROAD INSTITUTE, INC.	Direct detection of epigenetic modifications in their native chromatin contexts

PI Name	Institution Name	Title
RFA-RM-07-015: Discovery of Novel Epigenetic Marks in Mammalian Cells (R01)
KIKYO, NOBUAKI	UNIVERSITY OF MINNESOTA TWIN CITIES	Histone proline isomerization and gene regulation

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PI Name	Institution Name	Title
RFA-RM-07-016: Discovery of Novel Epigenetic Marks in Mammalian Cells (R21)
PARTHUN, MARK R (contact);  FREITAS, MICHAEL A	OHIO STATE UNIVERSITY	Identification of Histone Modification Interaction Networks

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PI Name	Institution Name	Title
RFA-RM-08-001: Construction of a Reference Sequence Data Set for the Human Microbiome Project (U54)
NELSON, KAREN E	J. CRAIG VENTER INSTITUTE, INC.	Construction of A Reference Sequence Data Set For The Human Microbiome Project

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PI Name	Institution Name	Title
RFA-RM-08-023: Patient-Reported Outcomes Measurement Information SystemTM (PROMIS) Research Sites (U01)
STONE, ARTHUR A. (contact);  BRODERICK, JOAN E	STATE UNIVERSITY NEW YORK STONY BROOK	Ecological validity of PROMIS instruments

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PI Name	Institution Name	Title
RFA-RM-08-025: Patient-Reported Outcomes Measurement Information SystemTM (PROMIS) Statistical Center (U54)
CELLA, DAVID	EVANSTON NORTHWESTERN HEALTHCARE	PROMIS Statistical Center