The Common Fund’s Library of Integrated Network-based Cellular Signatures (LINCS) program is developing a library of molecular signatures that describes how different types of cells respond to a variety of agents that disrupt normal cellular functions, called “perturbagens.” This library may help us better understand normal and diseased cellular states and how to alter them.
The program currently supports LINCS Data and Signature Generation Centers and coordinates with the NIH Big Data to Knowledge (BD2K) initiative through a BD2K-LINCS Data Integration and Coordination Center.
Archived Webcast of LINCS Outreach Meeting: You can now watch the archived webcast of the March 10-11th LINCS Outreach Meeting to learn more about LINCS and how big data is shaping the future of biomedical research. Browse the meeting agenda and other meeting information.
LINCS and Big Data in Genetics. Learn how high-throughput data from the LINCS program could contribute to our understanding of cancer and other diseases in this editorial from Nature.