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Funded Research

 
Large Scale Production of Perturbagen-Induced Cellular Signatures (U54) RFA-RM-10-003
PI Name Institution Name Title
GOLUB, TODD R. (contact) WINCKLER, WENDY BROAD INSTITUTE, INC. Large scale gene expression analysis of cellular states
MITCHISON, TIMOTHY J.(contact) SORGER, PETER KARL HARVARD UNIVERSITY (MEDICAL SCHOOL) Pharmaco Response Signatures and Disease Mechanism

 

Advanced Technologies for Detection of Perturbation-Induced Cellular Signatures (U01) RFA-RM-10-004
PI Name Institution Name Title
CALIFANO, ANDREA COLUMBIA UNIVERSITY HEALTH SCIENCES Profiling Signatures of synergistic Chemical Perturbations in Diverse Cellular C
JAFFE, JACOB DAVID (contact) MACCOSS, MICHAEL J BROAD INSTITUTE, INC. Accelerated Protein Signaling Signatures
MELDRUM, DEIRDRE R. ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Live-cell Microarray for high-throughput observation of metabolic signatures
MILLER-JENSEN, KATHRYN (contact) FAN, RONG YALE UNIVERSITY Detection of Protein Signal Transduction Signatures in Single Cells

 

Computational Tool Development and Integrative Data Analysis for LINCS (U01) RFA-RM-10-005
PI Name Institution Name Title
CALIFANO, ANDREA COLUMBIA UNIVERSITY HEALTH SCIENCES A Systems Approach to Elucidate Mechanisms of Drug Activity and Sensivity
MEDVEDOVIC, MARIO UNIVERSITY OF CINCINNATI Integrative statistical methods and tools for analysis of perturbation signatures
SCHURER, STEPHAN C UNIVERSITY OF MIAMI SCHOOL OF MEDICINE LINCS Information FramEwork (LIFE) to Integrate and Analyze Diverse Data Set
ZHOU, XIAOBO (contact) CHANG, CHUNG-CHE METHODIST HOSPITAL RESEARCH INSTITUTE itNETZ: Integrative and Translational Network-based Cellular Signature Analyzer
 
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