Induced Pluripotent Stem Cells and the NIH Intramural Research Program Wilson Hall, Building 1 NIH Main Campus Bethesda, MD January 15, 2010
9:30 – 9:45am Welcome and Opening Remarks
Francis S. Collins, MD, PhD, Director, NIH
Michael M. Gottesman, M.D., Deputy Director for Intramural Research, NIH 
9:45 – 11:05am Session 1: Generation and characterization of iPS cells - John O’Shea (chair) 
  • Shinya Yamanaka, Gladstone Institute UCSF “Induction of Pluripotency by Defined Factors” (15 min)

  • Helen Blau, Stanford
    “Reprogramming towards pluripotency requires AID-dependent DNA demethylation” (15 min)

  • Kristin K. Baldwin, Scripps
    “What we can learn from mice derived from induced pluripotent stem cells.” (15 min)

  • Ron McKay, NIH
    “Characterization of hES and iPS cells”

11:05 – 11:20am Break - cafeteria
11:20 – 12:20pm Session 2: Disease Modeling, Opportunities, and Issues, Part 1 - Paul Liu (chair) 
  • Rene Reijo Pera, Stanford
    "iPSCs and women's reproductive and somatic health" (15 min)

  • Linzhao Cheng, Johns Hopkins
    “Derivation and gene targeting of patient-specific iPS cells: towards disease modeling and treatment” (15 min)

  • Lorenz Studer, Memorial Sloan Kettering Cancer Center
    “iPSC based disease modeling in familial dysautonomia and other rare genetic disorders” (15 min)

12:20 – 1:30pm Lunch and Discussion – back of cafeteria
1:30 – 2:50pm Session 3: Disease Modeling, Opportunities, and Issues, Part 2 - Charles Dearolf (chair) 
  • Margret Goodell, Baylor
    “Activities and Opportunities in Pluripotential Stem Cell Research in the Texas Medical Center” (15 min)

  • David Scadden, Harvard
    TBA (15 min)

  • James Ellis, Hospital for Sick Children, Toronto
    “Pluripotency reporters and disease models”. (15 min)

  • Raj Puri, FDA
    "Scientific and Regulatory Perspectives on iPS Cell Derived Cellular Products" (15 min)

2:50 – 3:00pm Break – coffee provided
3:00 – 4:30pm Session 4: Informal discussion about possible roles for the Intramural Research Program
4:30pm Closing Remarks, Francis Collins and Michael Gottesman


This page last reviewed on May 6, 2014