Funded Research

Facile Methods and Technologies for Synthesis of Biomedically Relevant Carbohydrates (U01) RFA-RM-16-020
PI Name Institution Name Title
CRICH, DAVID WAYNE STATE UNIVERSITY Novel Methods and Technologies for Synthesis of Biomedically Relevant Carbohydrates
MONTGOMERY, JOHN (contact) 
NAGORNY, PAVEL 
SHERMAN, DAVID H 
UNIVERSITY OF MICHIGAN Catalytic Methods for Building Block Assembly and for Stereoselective Glycosylation
TANG, WEIPING UNIVERSITY OF WISCONSIN-MADISON Develop Catalytic Methods to Streamline the Assembly of Oligosaccharides
WALCZAK, MACIEJ ANDRZEJ UNIVERSITY OF COLORADO New Catalytic Methods for the Synthesis of Biomedically Relevant Carbohydrates
YU, HAI (contact) 
KIESSLING, LAURA L 
LI, LEI
UNIVERSITY OF CALIFORNIA AT DAVIS Chemoenzymatic synthesis of bacterial polysaccharides
ZHANG, LIMING (contact) 
ZHU, JIANGLONG
UNIVERSITY OF CALIFORNIA SANTA BARBARA Development of novel approaches for stereoselective construction of glycosidic linkages

 

Data Integration and Analysis Tools: Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Data in the Context of Comparable Gene, Protein, and Lipid Data (U01) RFA-RM-16-021
PI Name Institution Name Title
YORK, WILLIAM S (contact) 
MAZUMDER, RAJA
UNIVERSITY OF GEORGIA Computational and Informatics Resources and Tools for Glycoscience Research

 

Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01) RFA-RM-16-022
PI Name Institution Name Title
GRIMES, CATHERINE LEIMKUHLER UNIVERSITY OF DELAWARE Metabolic carbohydrate cell wall probes for bacterial structure and immune recognition studies
MAHAL, LARA K NEW YORK UNIVERSITY GlycoMiR: Mapping the miRNA-glycogene interactome
RUHL, STEFAN HANS-KLAUS (contact) 
SULLAM, PAUL M.
STATE UNIVERSITY OF NEW YORK AT BUFFALO HARNESSING THE ORAL MICROBIOME TO CREATE NOVEL GLYCAN-BINDING PROBES
SHE, JIN-XIONG AUGUSTA UNIVERSITY Luminex multiplex glycan array (LMGA): a high throughput and high content platform for GBPs
WANG, XU  ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Sequencing Glycosaminoglycans using Recognition Tunneling Nanopores
ZAIA, JOSEPH  BOSTON UNIVERSITY MEDICAL CAMPUS An open-source software suite for processing glycomics and glycoproteomics mass spectral data

 

Innovative Adaptations to Simplify Existing Technologies for Manipulation and Analysis of Glycans (U01) RFA-RM-16-023
PI Name Institution Name Title
REINHOLD, VERNON NYE UNIVERSITY OF NEW HAMPSHIRE Shaping MSn Technology for High Impact Glycan Sequencing
WOODS, ROBERT J (contact) 
YOUNG, JASMINE Y 
UNIVERSITY OF GEORGIA GlyProbity: tools to curate glycan structure pre and post deposition in the PDB
YANG, LORETTA GLYCOSENSORS AND DIAGNOSTICS, LLC Adapting multiplex microspheres to analyze glycosylation features by flow cytometry

 

Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (R21) RFA-RM-15-008
PI Name Institution Name Title
AMSTER, I JONATHAN UNIVERSITY OF GEORGIA Rapid Sequencing of Sulfated Glycans By CE-MS/MS
AZADI, PARASTOO  UNIVERSITY OF GEORGIA Glycan linkage and sequence plus determination of site of glycosylation by permethylation of glycopeptides and MSn analysis in a one pot experiment
BERN, MARSHALL WAYNE PROTEIN METRICS, INC. Glycopeptide Identification with a Comprehensive Proteomics Search Engine
DRAKE, RICHARD R.
 
MEDICAL UNIVERSITY OF SOUTH CAROLINA Detection and Histopathology Localization of O-Glycans and Glycosaminoglycans in Tissues
GHIRLANDA, GIOVANNA (contact) 
OZKAN, SEFIKA BANU
ARIZONA STATE UNIVERSITY-TEMPE CAMPUS New Tools for Glycoscience: Engineering Targeted Lectins by Computer-Guided Directed Evolution
GODULA, KAMIL (contact) 
GAGNEUX, PASCAL
UNIVERSITY OF CALIFORNIA SAN DIEGO Glycan array for phenotype-driven capture and genotyping of viruses in primary isolates
HAAB, BRIAN B. VAN ANDEL RESEARCH INSTITUTE On-chip Glycan Analysis of Clinical Specimens
HILI, RYAN UNIVERSITY OF GEORGIA Functionalized DNA as glycan recognition molecules
KOHLER, JENNIFER J UT SOUTHWESTERN MEDICAL CENTER Photocrosslinking probes to discover glycan-dependent interactions
LI, LINGJUN  UNIVERSITY OF WISCONSIN-MADISON    Mass Defect-based Chemical Tags for Multiplex Glycan Quantitation
LIN, CHENG BOSTON UNIVERSITY MEDICAL CAMPUS Characterization of glycan isomers by trapped ion mobility spectrometry-electron activated dissociation tandem mass spectrometry
LINSTEDT, ADAM D CARNEGIE-MELLON UNIVERSITY DRUG-LIKE MODULATORS TARGETING O-GLYCOSYLATION BY GalNAc TRANSFERASE-2/3
NYCHOLAT, CORWIN MICHAEL SCRIPPS RESEARCH INSTITUTE Developing high affinity ligands of glycan binding proteins
RANZINGER, RENE (contact) 
AOKI, KAZUHIRO
UNIVERSITY OF GEORGIA Development of high-throughput workflow for glycosphingolipid analysis and annotation
SONG, XUEZHENG EMORY UNIVERSITY Next generation glycan microarray (NGGM) enabled by next generation sequencing (NGS) and DNA-coded glycan library
TEYTON, LUC SCRIPPS RESEARCH INSTITUTE Production of high affinity anti-glycan and anti-glycolipid antibodies
ZENG, YONG UNIVERSITY OF KANSAS LAWRENCE Integrated Digital Microfluidic Platforms for Next-Generation Glycomics

 

Facile Methods and Technologies for Synthesis of Biomedically Relevant Carbohydrates (U01) RFA-RM-15-007
PI Name Institution Name Title
BENNETT, CLAY SAMUEL TUFTS UNIVERSITY MEDFORD Reagent Control for Stereoselective Glycosylation Reactions
BOONS, GEERT-JAN UNIVERSITY OF GEORGIA Streamlining the chemoenzymatic synthesis of asymmetrical glycans of biological importance
BRICHACEK, MATTHEW PAUL UNIVERSITY OF MAINE ORONO Transformative Methods for the Solid Phase Synthesis of Oligosaccharides
CHEN, XI (contact) 
WANG, PENG GEORGE
UNIVERSITY OF CALIFORNIA AT DAVIS Facile chemoenzymatic synthesis and purification of glycolipids
DEMCHENKO, ALEXEI V (contact) 
DE MEO, CRISTINA  
STINE, KEITH J.
UNIVERSITY OF MISSOURI-ST. LOUIS Refinement and implementation of the automated oligosaccharide synthesizer
NGUYEN, HIEN M UNIVERSITY OF IOWA Catalytic Methods for Stereoselective 1,2-Cis Glycosylation

 

Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01) RFA-RM-15-009
PI Name Institution Name Title
BERTOZZI, CAROLYN R (contact) 
PITTERI, SHARON 
STANFORD UNIVERSITY Making glycoproteomics via mass spectrometry more accessible to the greater scientific community
JU, TONGZHONG EMORY UNIVERSITY Novel Technologies for Quantitative O-glycomics and Amplification/Preparation of Cellular O-Glycans
WOODS, ROBERT J (contact) 
FOLEY, B. LACHELE
UNIVERSITY OF GEORGIA Tools to enable non-specialists to model glycoconjugates and glycan-protein interactions

 

Data Integration and Analysis Tools: Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Structural, Analytical, and Interaction Data in the Context of Comparable Gene, Protein, and Lipid Data (R34) RFA-RM-14-012
PI Name Institution Name Title
MAZUMDER, RAJA GEORGE WASHINGTON UNIVERSITY GlycoCentral: Glycobiology data and tool integration with genes, proteins and lipids
YORK, WILLIAM S. UNIVERSITY OF GEORGIA glySpace: an integrated infrastructure for Glycoinformatics

 

 
Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01) RFA-RM-14-013
PI Name Institution Name Title
CUMMINGS, RICHARD D (contact) 
MERNAUGH, RAYMOND L
BETH ISRAEL DEACONESS MEDICAL CENTER Smart Anti-Glycan Reagents to Generate the Human Glycome Atlas
VARKI, AJIT P UNIVERSITY OF CALIFORNIA SAN DIEGO Sialoglycan-Recognizing Probes for Defining Sialoglycomes in Biological Systems

 

 
Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (R21) RFA-RM-14-014
PI Name Institution Name Title
BERTOZZI, CAROLYN R STANFORD UNIVERSITY Revolutionizing the detection of O-GlcNAc
COBB, BRIAN A (contact) 
ABBOTT, DEREK W
CASE WESTERN RESERVE UNIVERSITY Glycome-Enhanced KnockOut (GEKO) Technology
COON, JOSHUA J UNIVERSITY OF WISCONSIN-MADISON Activated-Ion Negative Electron Transfer Dissociation For High-Throughput Glycoproteomics
NOVOTNY, MILOS INDIANA UNIVERSITY New Chromatographic Technologies for Resolving Carbohydrate Isomers
RUHL, STEFAN HANS-KLAUS (contact) 
SULLAM, PAUL M.
STATE UNIVERSITY OF NEW YORK AT BUFFALO MINING THE ORAL MICROBIOME FOR NOVEL GLYCAN-BINDING MOLECULES
SHE, JIN-XIONG GEORGIA REGENTS RESEARCH INSTITUTE INC Multiplex Luminex glycan array for large scale analyses of glycan-binding proteins
STOJANOVIC, MILAN N COLUMBIA UNIVERSITY HEALTH SCIENCES Automated Microfluidic Selection of Aptamers against Carbohydrates
TANG, KEQI BATTELLE PACIFIC NORTHWEST LABORATORIES A hybrid IMS-MS platform for ultrasensitive and high resolution glycan analysis
WANG, LIANCHUN UNIVERSITY OF GEORGIA Using CRISPR-Cas9 technology to develop a mutant cell library for heparan sulfate structure-function study
WANG, XU ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Single Molecule Sequencing of Glycosaminoglycans using Recognition Tunneling Nanopores
WEST, CHRISTOPHER M. (contact) 
TARLETON, RICK L 
WELLS, LANCE
UNIVERSITY OF GEORGIA Enabling tools for protists pathogen glycobiology
ZACHARA, NATASHA ELIZABETH JOHNS HOPKINS UNIVERSITY Chemical Genetic Tools for the Spatial and Temporal Modulation of O-GlcNAcylation
ZAIA, JOSEPH BOSTON UNIVERSITY Software for automated interpretation of heparan sulfate tandem mass spectra

 

 
Facile Methods and Technologies for Synthesis of Biomedically Relevant Carbohydrates (U01) RFA-RM-14-015
PI Name Institution Name Title
CHAIKOF, ELLIOT (contact) 
CUMMINGS, RICHARD D
BETH ISRAEL DEACONESS MEDICAL CENTER Facile Synthesis of Glycosulfopeptides and Related Bioconjugates
HSIEH-WILSON, LINDA C (contact) 
HUANG, XUEFEI
CALIFORNIA INSTITUTE OF TECHNOLOGY Expedited Synthesis of Glycosaminoglycans Containing Defined Sulfation Domains

JACOBSEN, ERIC N

HARVARD COLLEGE Small-Molecule Catalysts for the Stereoselective Synthesis of Oligosaccharides
POHL, NICOLA L INDIANA UNIVERSITY Sugar Building Blocks and Automated Synthesis of Biomedically-Relevant Glycans
SONG, XUEZHENG (contact) 
REINHOLD, VERNON NYE
EMORY UNIVERSITY Facile Chemical Methods for Reverse Synthesis and Large Scale Production of Biomedically Relevant Glycan Libraries
WANG, PENG GEORGE (contact) 
LI, LEI
GEORGIA STATE UNIVERSITY Facile Synthesis of O-Glycans and O-Glycopeptides

 


 

This page last reviewed on September 5, 2017