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Funded Research

 

2014 NIH CRM Therapeutic Challenge Award

PI Name Institution Name Title

BHARTI, KAPIL

NATIONAL EYE INSTITUTE

An Autologous Cell Based Therapy Using iPS Cell-Derived RPE

 

2012 NIH CRM Pilot Projects for Clinical Applications

PI Name Institution Name Title

BONNEMANN, CARSTEN

NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

Using iPSC to model the neurological phenotype of alpha-dystroglycanopathie

LIANG, T. JAKE

NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES

iPSC-derived Human Hepatocytes: A Model for Treatment of Liver Disease

LIU, PAUL P.

NATIONAL HUMAN GENOME RESEARCH INSTITUTE

Towards cell therapy for FPD/AML with patient-specific iPS cells

MILLER, SHELDON

NATIONAL EYE INSTITUTE

Constructing Functional iPSC-derived RPE Tissue for Cell-based Therapy

RESTIFO, NICHOLAS

NATIONAL CANCER INSTITUTE

Regenerative medicine using lineage reprogramming of tumor-specific T cells

USDIN, KAREN

NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES

Making neurons from FX iPSCs to study disease pathology and to screen for drugs

 

2011 NIH CRM Pilot Projects for Clinical Applications
PI Name Institution Name Title
BOEHM, MANFRED NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Reprogramming and lineage differentiations of IPS cells from HIES patients
DENG, CHUXIA NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES Targeted correction of human and mouse iPS cells for liver diseases
DUNBAR, CYNTHIA NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Preclinical Development of reprogrammed cells utilizing the rhesus macaque
FISCHBECK, KENNETH NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE An iPS cell system for the study of motor neuron disease
JETTEN, ANTON NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES Induction of pancreatic beta cell development in iPS cells by GLIS3
MALECH, HARRY NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES Gene Repaired Autologous iPSC to treat Chronic Granulomatous Disease
MILLER, SHELDON NATIONAL EYE INSTITUTE Mechanisms of AMD Initiation Using iPS Cell-Derived RPE
PARK, JOHN NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE Stimulation of anti-glioma immune responses by iPS cell-derived microglia
SARTORELLI, VITTORIO NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES Role of Epigenetic Regulators in iPS and SCNT-derived ESCs
SIDRANSKY, ELLEN NATIONAL HUMAN GENOME RESEARCH INSTITUTE iPSc to study and treat Gaucher disease and associated parkinsonism
SWAROOP, ANAND NATIONAL EYE INSTITUTE Therapies for early onset retinal degeneration using iPS cell technology
WESTPHAL, HEINER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT iPS cells for the analysis and treatment of SLOS, a rare childhood disorder
YOUNG, NEAL NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Induced pluripotent stem cells to model telomere regulation and cell therapy

2010 NIH CRM Pilot Projects for Clinical Applications
PI Name Institution Name Title
AUSTIN, CHRISTOPHER NATIONAL HUMAN GENOME RESEARCH INSTITUTE Development of iPS Cell-Based Disease Model of Niemann-Pick Disease Type C
BOHELER, KENNETH NATIONAL INSTITUTE OF AGING Isolation of "homogeneous" human iPS cell populations
FINKEL, TOREN NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Cardiovascular Applications of iPS Cells
FISCHBECK, KENNETH NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE iPS cells for mechanistic and therapeutic studies of motor neuron disease
KELLEY, MATTHEW NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS Induction of hair cell regeneration using induced pluripotent stem cells
KUEHN, MICHAEL NATIONAL CANCER INSTITUTE Assessing the Smads2/3 dependent epigenetic landscape in iPSC
LIU, PAUL P NATIONAL HUMAN GENOME RESEARCH INSTITUTE Development of a Reference Set of Comprehensively Characterized iPS cell li
MILLER, SHELDON NATIONAL EYE INSTITUTE Restoring Vision: Criteria for iPS Cell Derived Retinal Pigment Epithelia
RESTIFO, NICHOLAS NATIONAL CANCER INSTITUTE Reprogramming tumor-specific T cells using iPS for cancer immunotherapy
ROBEY, PAMELA NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH Differentiation of human iPSCs into bone and cartilage
WEINBERGER, DANIEL NATIONAL INSTITUTE OF MENTAL HEALTH Validation of human GABA inter-neurons derived from iPS cells

 

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