Extracellular RNA Communication
| Clinical Utility of Extracellular RNA for Therapy Development (UH2/UH3) RFA-RM-12-014 In 2016 the awards below transitioned into their UH3 phase. The UH2 phase (first phase) of these awards focused on discovery and feasibility, while the UH3 phase will focus on testing and validation of the therapeutics. |
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| PI Name | Institution Name | Title |
|---|---|---|
| ABDEL-MAGEED, ASIM B | TULANE UNIVERSITY OF LOUISIANA |
Targeting Tumor-Derived exRNA-Containing Microvesicles by High Throughput Screeni |
| MATIN, AC | STANFORD UNIVERSITY | HER2-targeted exosomal delivery of therapeutic mRNA for enzyme pro-drug therapy |
| SCHMITTGEN, THOMAS D (contact) PHELPS, MITCH A |
UNIVERSITY OF FLORIDA | Targeted delivery of microRNA-loaded microvesicle for cancer therapy |
Clinical Utility of Extracellular RNA for Biomarker Development (UH2/UH3) RFA-RM-12-013 |
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| PI Name | Institution Name | Title |
|---|---|---|
CARTER, BOB S (contact) |
UNIVERSITY OF CALIFORNIA SAN DIEGO |
|
DAS, SAUMYA (contact) |
BETH ISRAEL DEACONESS MEDICAL CENTER |
Plasma miRNA predictors of adverse mechanical and electrical remodeling after MI |
FREEDMAN, JANE E |
UNIV OF MASSACHUSETTS MED SCH WORCESTER |
Extracellular RNAs: Biomarkers for Cardiovascular Risk and Disease |
JENSEN, KENDALL(contact) |
TRANSLATIONAL GENOMICS RESEARCH INST |
|
LAURENT, LOUISE C |
UNIVERSITY OF CALIFORNIA SAN DIEGO |
ExRNAs for Early Identification of Pregnancies at Risk for Placental Dysfunction |
PATEL, TUSHAR |
MAYO CLINIC JACKSONVILLE |
Extracellular non-coding RNA biomarkers of hepatocellular cancer |
SAUGSTAD, JULIE ANNE (contact) |
OREGON HEALTH AND SCI UNIVERSITY |
Clinical Utility of MicroRNAs as Diagnostic Biomarkers of Alzheimers Disease |
TUSCHL, THOMAS (contact) |
ROCKEFELLER UNIVERSITY |
Clinical utility of extracellular RNA as marker of kidney disease progression |
WEINER, HOWARD L |
BRIGHAM AND WOMEN'S HOSPITAL |
Circulating MicroRNAs as Disease Biomarkers in Multiple Sclerosis |
WONG, DAVID T |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
Clinical Utility of Salivary ExRNA Biomarkers for Gastric Cancer Detection |
Clinical Utility of Extracellular RNA for Therapy Development (UH2/UH3) RFA-RM-12-014 In August 2015, the awards below transitioned into their UH3 phase. The UH2 phase (first phase) of these awards focused on discovery and feasibility, while the UH3 phase will focus on testing and validation of the therapeutics. |
||
| PI Name | Institution Name | Title |
|---|---|---|
| ABDEL-MAGEED, ASIM, B | TULANE UNIVERSITY OF LOUISIANA | Targeting Tumor-Derived exRNA-Containing Microvesicles by High Throughput Screeni |
ARONIN, NEIL |
UNIV OF MASSACHUSETTS MED SCH WORCESTER |
|
KRAIG, RICHARD P |
UNIVERSITY OF CHICAGO |
|
| MATIN, AC | STANFORD UNIVERSITY | HER2-targeted exosomal delivery of therapeutic mRNA for enzyme pro-drug therapy |
QUESENBERRY, PETER J |
RHODE ISLAND HOSPITAL |
Regulation of renal and bone marrow injury by extracellular vesicle non-coding RN |
| SCHMITTGEN, THOMAS D (contact) PHELPS, MITCH A |
UNIVERSITY OF FLORIDA | Targeted delivery of microRNA-loaded microvesicle for cancer therapy |
SOOD, ANIL K (contact) |
UT MD ANDERSON CANCER CTR |
Novel extra cellular RNA-based combinatorial RNA inhibition therapy |
ZHANG, HUANG-GE (contact) |
UNIVERSITY OF LOUISVILLE |
Fruit exosome-like particles for therapeutic delivery of extracellular miRNAs |
| NIH Support for Conferences and Scientific Meetings (Parent R13/U13) PA-13-347 | ||
| PI Name | Institution Name | Title |
|---|---|---|
| GUO, PEIXUAN | GORDON RESEARCH CONFERENCES |
|
| QUESENBERRY, PETER J | GORDON RESEARCH CONFERENCES | 2016 Extracellular Vesicles Gordon Research Conference |
| WITWER, KENNETH W | JOHNS HOPKINS UNIVERSITY | International Society for Extracellular Vesicles - Education Day & Meeting |
| WOODLAND, DAVID L. | KEYSTONE CONFERENCE CENTER | Exosomes/Microvesicles: Novel Mechanisms of Cell-Cell Communication |
| PI Name | Institution Name | Title |
|---|---|---|
FREEDMAN, JANE E (contact) |
UNIV OF MASSACHUSETTS MED SCH WORCESTER |
|
GALAS, DAVID J. (contact) |
PACIFIC NORTHWEST RESEARCH INSTITUTE |
Reference Profiles of Extracellular RNA in 4 Body Fluids of Healthy Humans |
GHIRAN, IONITA CALIN |
BETH ISRAEL DEACONESS MEDICAL CENTER |
|
LAURENT, LOUISE C |
UNIVERSITY OF CALIFORNIA SAN DIEGO |
|
TEWARI, MUNEESH |
UNIVERSITY OF MICHIGAN AT ANN ARBOR |
Reference Profiles of ExRNA in Biofluids from Well-Defined Human Cohorts |
WOODRUFF, PRESCOTT G (contact) |
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO |
Defining A Comprehensive Reference Profile of Circulating Human Extracellular RNA |
| Data Management and Resource Repository (DMRR) on Extracellular RNA (U54) RFA-RM-12-010 | ||
| PI Name | Institution Name | Title |
|---|---|---|
| MILOSAVLJEVIC, ALEKSANDAR (contact) GALAS, DAVID J. GERSTEIN, MARK BENDER |
BAYLOR COLLEGE OF MEDICINE | Data management and Resource Repository for the exRNA Atlas |
| Extracellular RNA Biogenesis, Biodistribution, Uptake, and Effector Function (U19) RFA-RM-12-012 | ||
| PI Name | Institution Name | Title |
|---|---|---|
| BLELLOCH, ROBERT H | UNIVERSITY OF CALIFORNIA-SAN FRANCISCO | In Vivo Regulated Release and Function of Extracellular Small RNAs |
| BREAKEFIELD, XANDRA OWENS (contact) CHAREST, ALAIN GOULD, STEPHEN J KRICHEVSKY, ANNA M. MEMPEL, THORSTEN ROMAN |
MASSACHUSETTS GENERAL HOSP | exRNA released by glioblastoma alters brain microenvironment |
| COFFEY, ROBERT J. | VANDERBILT UNIVERSITY MED CTR | Secreted RNA during CRC progression biogenesis function and clinical markers |
| MCMANUS, MICHAEL T | UNIVERSITY OF CALIFORNIA-SAN FRANCISCO | Genetic models for exRNA communication |
| TUSCHL, THOMAS | ROCKEFELLER UNIVERSITY | Definition of Serum Ribonucleoprotein Composition and its Regulation and Function |
Clinical Utility of Extracellular RNA for Biomarker Development (UH2/UH3) RFA-RM-12-013 |
||
| PI Name | Institution Name | Title |
|---|---|---|
CARTER, BOB S (contact) |
UNIVERSITY OF CALIFORNIA SAN DIEGO |
|
DAS, SAUMYA (contact) |
BETH ISRAEL DEACONESS MEDICAL CENTER |
Plasma miRNA predictors of adverse mechanical and electrical remodeling after MI |
FREEDMAN, JANE E |
UNIV OF MASSACHUSETTS MED SCH WORCESTER |
Extracellular RNAs: Biomarkers for Cardiovascular Risk and Disease |
JENSEN, KENDALL(contact) |
TRANSLATIONAL GENOMICS RESEARCH INST |
|
LAURENT, LOUISE C |
UNIVERSITY OF CALIFORNIA SAN DIEGO |
ExRNAs for Early Identification of Pregnancies at Risk for Placental Dysfunction |
PATEL, TUSHAR |
MAYO CLINIC JACKSONVILLE |
Extracellular non-coding RNA biomarkers of hepatocellular cancer |
SAUGSTAD, JULIE ANNE (contact) |
OREGON HEALTH AND SCI UNIVERSITY |
Clinical Utility of MicroRNAs as Diagnostic Biomarkers of Alzheimers Disease |
TUSCHL, THOMAS (contact) |
ROCKEFELLER UNIVERSITY |
Clinical utility of extracellular RNA as marker of kidney disease progression |
WEINER, HOWARD L |
BRIGHAM AND WOMEN'S HOSPITAL |
Circulating MicroRNAs as Disease Biomarkers in Multiple Sclerosis |
WONG, DAVID T |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
Clinical Utility of Salivary ExRNA Biomarkers for Gastric Cancer Detection |
This page last reviewed on July 14, 2017