Funded Research

Collaborative Activities to Promote Metabolomics Research (Admin Supp) PA-16-005
PI Name Institution Name Title
BHATTACHARYA, DEEPTA WASHINGTON UNIVERSITY TRANSCRIPTIONAL REGULATION OF ANTIBODY RESPONSES AND IMMUNITY
FILLINGIM, ROGER B UNIVERSITY OF FLORIDA Ethnic Differences in Responses to Painful Stimuli
GILLIES, ROBERT J. H. LEE MOFFITT CANCER CTR & RES INST Causes & Consequences of Acid pH in Tumors
HOOK, VIVIAN Y. H. UNIVERSITY OF CALIFORNIA SAN DIEGO Role of Human-Specific Cathepsin V Protease in the Production of Opioid and Related Peptide
JAFFREY, SAMIE R WEILL MEDICAL COLL OF CORNELL UNIV mRNA methylation: A noval mechanism that blocks signaling by drugs of abuse
JERRY, D., JOSEPH (contact) 
SCHNEIDER, SALLIE SMITH		 UNIVERSITY OF MASSACHUSETTS AMHERST Disruption of parity-induced tumor suppressor pathways by xenoestrogen exposures
LENGYEL, ERNST UNIVERSITY OF CHICAGO Regulation of Adhesion and Proteolysis in Ovarian Cancer
MCCABE, LAURA R (contact) 
BRITTON, ROBERT A 
PARAMESWARAN, NARAYANAN		 MICHIGAN STATE UNIVERSITY Mechanistic basis of probiotic prevention of osteoporosis
SHAIKH, SAAME R EAST CAROLINA UNIVERSITY Suppressing inflammation and boosting humoral immunity with n-3 PUFAs
SUTHANTHIRAN, MANIKKAM WEILL MEDICAL COLL OF CORNELL UNIV Biomolecular Markers for Safe Minimization of Immunosuppression
TIROUVANZIAM, RABIN EMORY UNIVERSITY Contribution of neutrophils to early airway disease in cystic fibrosis children
WONDISFORD, FREDRIC E. RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL Transcriptional coactivators and hepatic glucose production

 

Metabolomics Data Analysis (R03) RFA-RM-15-021
PI Name Institution Name Title
BERGMANN, SVEN UNIVERSITY OF LAUSANNE INTEGRATION OF METABOLOMICS AND GENOMICS DATA TO INVESTIGATE CARDIOVASCULAR RISK
DORRESTEIN, PIETER C UNIVERSITY OF CALIFORNIA SAN DIEGO Reuse of Public Metabolomics Data
HERRINGTON, DAVID MCLEOD  WAKE FOREST UNIVERSITY HEALTH SCIENCES Multi-Block Latent Variable Models for Statistical Integration of Multi-Platform Metabolomic Data
KARNOVSKY, ALLA UNIVERSITY OF MICHIGAN Application of sparse partial correlation-based modeling for the analysis of high throughput metabolomics data
KARP, PETER D SRI INTERNATIONAL Pathway-based Metabolomics Data Analysis
LEE, KYONGBUM TUFTS UNIVERSITY MEDFORD A Machine-Learning Based Software Widget for Resolving Metabolite Identities
NEMES, PETER (contact) 
ZENG, CHEN		 GEORGE WASHINGTON UNIVERSITY Critical Transition-based Correlation Analysis for Metabolomics
PROMISLOW, DANIEL EDWARD (contact) 
SHOJAIE, ALI 		 UNIVERSITY OF WASHINGTON Multi-group covariance estimation for metabolomic analysis with applications to neurodegenerative disease
SCHOLTENS, DENISE M  NORTHWESTERN UNIVERSITY AT CHICAGO Bayesian Network Models for Genetics and Metabolomics Studies of Fetal Programming
SNYDER, NATHANIEL W. DREXEL UNIVERSITY The influence of prenatal maternal exposures on fetal sterol metabolomics
SPRATT, HEIDI UNIVERSITY OF TEXAS MEDICAL BR GALVESTON A Multi-Omics Approach to Identify a Biomarker Panel for the Early Detection of Hepatocellular Carcinoma in Hepatitis C+ Individuals
WANG, CHI (contact) 
FLIGHT, ROBERT MAXWELL		 UNIVERSITY OF KENTUCKY Differential Abundance Methods for Large Heterogeneous-Featured Metabolomics Datasets
ZHANG, MIN PURDUE UNIVERSITY New Statistical Methods to Model Metabolite Profiles for Disease Detection

 

Collaborative Activities to Promote Metabolomics Research (Admin Supp) PA-15-030
PI Name Institution Name Title
BABA, SHAHID P UNIVERSITY OF LOUISVILLE Cardiac pathophysiology of histidyl dipeptides
CHENG, LEO L MASSACHUSETTS GENERAL HOSPITAL Characterizing Prostate Cancer By ex vivo MRS Signatures
CLARK, MAGGIE LYNN COLORADO STATE UNIVERSITY Community-based Participatory Research: A Tool to Advance Cookstove Interventions
CORWIN, ELIZABETH JEANNE (contact) 
DUNLOP, ANNE LANG		 EMORY UNIVERSITY Biobehavioral Determinants of the Microbiome and Preterm Birth in Black Women
GINSBERG, HENRY N COLUMBIA UNIVERSITY HEALTH SCIENCES Assembly and Secretion of APOB Containing Lipoproteins
HOLLAND, NINA UNIVERSITY OF CALIFORNIA BERKELEY Molecular Mechanisms of Obesity in Children Exposed to Phthalates in Utero 
HOLLAND, WILLIAM L UT SOUTHWESTERN MEDICAL CENTER Adiponectin Receptors and S1P Signaling in Beta Cell Survival and Proliferation
JACOB, SAMSON T (contact) 
GHOSHAL, KALPANA		 OHIO STATE UNIVERSITY Molecular mechanism of diet-induced carcinogenesis
JANSSON, THOMAS UNIVERSITY OF COLORADO DENVER Molecular Mechanisms Regulating Placental Nutrient Transporters
JONES, ALAN E UNIVERSITY OF MISSISSIPPI MEDICAL CENTER L-carnitine Treatment for Vasopressor Dependent Septic Shock
KARAGAS, MARGARET RITA DARTMOUTH COLLEGE Childrens Environmental Health & Disease Prevention Research Center at Dartmouth
LOZUPONE, CATHERINE (contact) 
PALMER, BRENT E		 UNIVERSITY OF COLORADO DENVER Factors mediating gut microbiota dysbiosis and metabolic disease in HIV patients
MILLER, MICHAEL A UNIVERSITY OF ALABAMA AT BIRMINGHAM Prostaglandins in C. elegans Fertilization
ROEPE, PAUL D. (contact) 
SULLIVAN, DAVID JOSEPH		 GEORGETOWN UNIVERSITY Optimized Combination Antimalarial Drug Therapy
VOORA, DEEPAK DUKE UNIVERSITY Development Of Prognostic Platelet RNA Biomarkers To Tailor Antiplatelet Therapy
WANG, MENG CARLA BAYLOR COLLEGE OF MEDICINE LIPID SIGNALING IN REGULATION OF LONGEVITY
WILEY, JENNY L. RESEARCH TRIANGLE INSTITUTE Sex Differences in Cannabinoid Dependence and Analgesia
XAVIER, JOAO SLOAN-KETTERING INSTITUTE FOR CANCER RES Engineering microbial social interactions: Towards new anti-biofilm therapies

 

Collaborative Activities to Promote Metabolomics Research (Admin Supp) PA-14-003
PI Name Institution Name Title
CRAPO, JAMES NATIONAL JEWISH HEALTH Metabolomic Signatures of Emphysema and COPD Progression in the COPDGene Cohort
CAI, LU UNIVERSITY OF LOUISVILLE Metabolomics study on the preventive mechanisms for LDR on diabetic nephropathy
CZEISLER, CHARLES BRIGHAM AND WOMEN'S HOSPITAL Sleep, Aging and Circadian Rhythm Disorders
ELLINGROD, VICKI L UNIVERSITY OF MICHIGAN Antipsychotic and Folate Pharmacogenetics - Metabolomics Supplement
GARCIA, ANDRES GEORGIA INSTITUTE OF TECHNOLOGY Hydrogels for hMSC Delivery & Engraftment
GOODYEAR, LAURIE JOSLIN DIABETES CENTER Exercise Regulation of Glucose Homeostasis Administrative Supplement
GUMP, BROOKS SYRACUSE UNIVERSITY Environmental Toxicants, Race, and Cardiovascular Disease Risk in Children
HATZOGLOU, MARIA CASE WESTERN RESERVE UNIVERSITY REGULATION OF GENE EXPRESSION DURING STRESS
HERTZ-PICCIOTTO, IRVA UNIVERSITY OF CALIFORNIA AT DAVIS THE CHARGE STUDY: CHILDHOOD AUTISM RISKS FROM GENETICS AND THE ENVIRONMENT
JOHNSON, STEPHEN L WASHINGTON UNIVERSITY Regulation of Adult Stem Cells in Zebrafish
MEADOR, KIMFORD J (contact)
PENNELL, PAGE BUCKHANNAN		 EMORY UNIVERSITY Investigates the Metabolomic Indicators of Neurodevelop Risk in Children of Pregnant Women with Epilepsy
MORA, SAMIA BRIGHAM AND WOMEN'S HOSPITAL HDL Heterogeneity and Function, Statin Therapy, and CVD Outcomes
PATEL, MANISHA N UNIVERSITY OF COLORADO DENVER Gamma-ketoaldehydes in Epileptogenesis
ROBBINS, PAUL D. SCRIPPS RESEARCH INSTITUTE Cell Autonomous and Non-Autonomous Mechanisms of Aging
SABA, JULIE CHILDREN'S HOSPITAL & RES CTR AT OAKLAND S1P Lyase in Colon Cancer
SCHENK, SIMON UNIVERSITY OF CALIFORNIA SAN DIEGO SIRT1 and Muscle Insulin Sensitivity
TRUSHINA, EUGENIA MAYO CLINIC ROCHESTER Mitochondrial Dynamics and Metabolomic Biomarkers in Neurodegenerative Disorders
WENDE, ADAM RAYMOND UNIVERSITY OF ALABAMA AT BIRMINGHAM Mechanisms of Glucose Mediated Cardiac Mitochondrial Dysfunction
WRIGHT, KENNETH P UNIVERSITY OF COLORADO METABOLIC AND COGNITIVE CONSEQUENCES OF SLEEP LOSS
     

 

Collaborative Activities to Promote Metabolomics Research (Admin Supp) PA-13-041
PI Name Institution Name Title
BARON, JOHN ANTHONY UNIVERSITY OF NORTH CAROLINA CHAPEL HILL A Pilot Metabolomic Study of the Effects of Vitamin D and Calcium Supplementation
ERZURUM, SERPIL C.  CLEVELAND CLINIC LERNER COM-CWRU ASTHMA BIOREPOSITORY CORE
COX, CHARLES LEROY UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN Synaptic Phenotype, Development, and Plasticity in the Fragile X Mouse
DE BOER, IAN H UNIVERSITY OF WASHINGTON Insulin Resistance in Chronic Kidney Disease
DORGAN, JOANNE F UNIVERSITY OF MARYLAND BALTIMORE PROSPECTIVE STUDY OF SERUM MIS AND GYNECOLOGIC CANCER RISK
GIRNUN, GEOFFREY D UNIVERSITY OF MARYLAND BALTIMORE METABOLIC CONTROL OF HEPATOCELLULAR CARCINOMA BY PGC1ALPHA
GOODELL, MARGARET BAYLOR COLLEGE OF MEDICINE Regulation of Hematopoietic Progenitors by de novo DNA Methylation
HIRSCHHORN, JOEL N CHILDREN'S HOSPITAL CORPORATION CANDIDATE GENE STUDIES OF OBESITY GUIDED BY WHOLE GENOME ASSOCIATION DATA
KARNIK, PRATIMA CASE WESTERN RESERVE UNIVERSITY PPAR-gamma Signaling in Normal Pilosebaceous Units and in Scarring Alopecia
LANFEAR, DAVID E HENRY FORD HEALTH SYSTEM IMPACT OF RACE AND GENETIC FACTORS ON BETA-BLOCKER EFFECTIVENESS IN HEART FAILURE
LI, CHRISTOPHER I FRED HUTCHINSON CAN RES CTR BREAST AND OVARY CANCER CLINICAL VALIDATION CENTER
LOYD, JAMES E VANDERBILT UNIVERSITY MED CTR HORMONAL, METABOLIC AND SIGNALING INTERACTIONS IN PAH
MASHEK, DOUGLAS G REGENTS OF THE UNIVERSITY OF MINNESOTA Role of ATGL in lipid droplet and nuclear lipidomes
PIAZZA, GARY A UNIVERSITY OF SOUTH ALABAMA PHOSPHODIESTERASE 5: A NOVEL TARGET AND INHIBITOR FOR BREAST CANCER CHEMOPREVENTI
POLYAK, STEPHEN J. UNIVERSITY OF WASHINGTON Effects of Silymarin on the Metabolome
ROHWER, FOREST SAN DIEGO STATE UNIVERSITY Ecology of Cystic Fibrosis: Administrative Supplement
ROSENBERG, PAUL B DUKE UNIVERSITY THE ROLE OF STIM1 IN CARDIAC AND SKELETAL MUSCLE FUNCTION
SOBOL, ROBERT W UNIVERSITY OF PITTSBURGH NOVEL APPROACHES TO ENHANCE TUMOR CELL CYTOTOXICITY OF ALKYLATING AGENTS
ULLMAN, BUDDY OREGON HEALTH & SCIENCE UNIVERSITY GENETIC ANALYSIS OF PURINE METABOLISM IN LEISHMANIA DONOVANI
YOUNGER, JOHN G REGENTS OF THE UNIVERSITY OF MINNESOTA Complement C5A in Human Sepsis

 

Collaborative Activities to Promote Metabolomics Research (Admin Supp) NOT-RM-11-024
PI Name Institution Name Title
ACCILI, DOMENICO COLUMBIA UNIVERSITY HEALTH SCIENCES Mouse models of insulin resistance
BERTHOUD, HANS-RUDOLF PENNINGTON BIOMEDICAL RESEARCH CENTER Neural mechanisms controlling food intake and body weight after bariatric surgery
CANTORNA, MARGHERITA T PENNSYLVANIA STATE UNIVERSITY-UNIV PARK Vitamin D Fluctuations and the Mucosal Immune Response
FELDMAN, HAROLD  UNIVERSITY OF PENNSYLVANIA The Chronic Renal Insufficiency Cohort (CRIC) Study: Scientific and Data Coordinating Center
FRY, REBECCA UNIVERSITY OF NORTH CAROLINA CHAPEL HILL In Utero Exposure to Arsenic, Links to Epigenetic Alterations and Disease
GOLUB, MARI S. UNIVERSITY OF CALIFORNIA, DAVIS Fluoxetine: Sensitive Ages and Genotypes for Adverse Effects in Juvenile Monkeys
HANNA-ROSE, WENDY PENNSYLVANIA STATE UNIVERSITY Probing Function of NAM and NAD+ Salvage in Development and Aging in C. elegans
KRON, STEPHEN UNIVERSITY OF CHICAGO Radiation Response within the Tumor Microenvironment
LAZAR, MITCHELL UNIVERSITY OF PENNSYLVANIA Thyroid Hormone Receptor: Regulation and Function
LIAO, RONGLIH BRIGHAM AND WOMEN'S HOSPITAL Molecular Mechanisms and Treatment of Primary Amyloid (AL) Cardiomypathy 
ROBACK, JOHN EMORY UNIVERSITY Adverse Effect of RBC transfusions: A unifying hypothesis
SETH, PANKAJ  BETH ISRAEL DEACONESS MEDICAL CENTER Pathway Specific Imaging in VHL Deficient Renal Cancer
VANDENBORNE, KRISTA UNIVERSITY OF FLORIDA Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy
WEISS, ELLEN UNIVERSITY OF NORTH CAROLINA, CHAPEL HILL Desensitization of Cone Visual Signaling Pathways

 

Mentored Research Scientist Development Award in Metabolomics (K01) RFA-RM-12-025
PI Name Institution Name Title
GOODING, JESSICA DUKE UNIVERSITY Metabolic Regulators of Insulin Secretion and Insulin Resistance
GROSSMANN, RUTH ELIZABETH UNIVERSITY OF IOWA Metabolomic Biomarkers of a Nutritional Intervention to Prevent Weight Gain
MITSCHE, MATTHEW ALVIN UT SOUTHWESTERN MEDICAL CENTER Determining the Function of PNPLA3 Utilizing Metabolomics and Stable Isotope Labe
THERIOT, CASEY UNIVERSITY OF MICHIGAN Shifts in the Gastrointestinal Metabolome During Clostridium difficile Infection
VIADER, ANDREU SCRIPPS RESEARCH INSTITUTE Lipidomic mapping of the cellular anatomy of brain endocannabinoid metabolism
YIM, SUN HEE BRIGHAM AND WOMEN'S HOSPITAL Metabolomics of Aging

 

Regional Comprehensive Metabolomics Resource Cores (RCMRC) (U24) RFA-RM-11-016
PI Name Institution Name Title
EDISON, ARTHUR S (contact)
YOST, RICHARD A.		 UNIVERSITY OF FLORIDA Southeast Resource Center for Integrated Metabolomics (SECIM)
HIGASHI, RICHARD M (contact)
FAN, TERESA W-M
LANE, ANDREW N
MOSELEY, HUNTER NATHANIEL		 UNIVERSITY OF KENTUCKY Resource Center for Stable Isotope-Resolved Metabolomics
NAIR, K SREEKUMARAN MAYO CLINIC Mayo Clinic Metabolomics Resource Core

 

Metabolomics Data Repository and Coordinating Center (U01) RFA-RM-11-020
PI Name Institution Name Title
SUBRAMANIAM, SHANKAR UNIVERSITY OF CALIFORNIA SAN DIEGO The Metabolomics Data Center and Workbench (MDCW)

 

Technology Development to Enable Large Scale Metabolomics Analyses (R01) RFA-RM-11-019

PI Name Institution Name Title

BAKER, ERIN S

BATTELLE PACIFIC NORTHWEST LABORATORIES

Platform Providing Increased Throughput, Sensitivity and Specificity for Metabolo

FAN, TERESA W-M (contact)
HIGASHI, RICHARD M
MOSELEY, HUNTER NATHANIEL
NANTZ, MICHAEL H

UNIVERSITY OF LOUISVILLE

Integrated Chemoselective and Informatic Platform for Large-Scale Metabolomics

HU, JIAN ZHI

BATTELLE PACIFIC NORTHWEST LABORATORIES

Slow-MAS NMR Metabolomics

MURPHY, ROBERT CARL

UNIVERSITY OF COLORADO DENVER

High Throughput Lipidomics Analysis by MALDI/Ion Mobility Mass Spectrometry

PATTERSON, ANDREW

PENNSYLVANIA STATE UNIVERSITY-UNIV PARK

Optimized Metabolite Extraction, Separation, and Identification for Metabolomics

PATTI, GARY JOSEPH

WASHINGTON UNIVERSITY

Developing the Untargeted Metabolomic Workflow for High-Throughput Analyses

 

Development of Courses or Workshops in Metabolomics (R25) RFA-RM-11-018

PI Name Institution Name Title

BARNES, STEPHEN

UNIVERSITY OF ALABAMA AT BIRMINGHAM

UAB Metabolomics Workshop: from design to decision

KOHLMEIER, MARTIN

UNIVERSITY OF NORTH CAROLINA CHAPEL HILL

Online learning platform: introducing clinicians and researchers to metabolomics

 

Mentored Research Scientist Development Award in Metabolomics (K01) RFA-RM-11-017

PI Name Institution Name Title

AMMONS, MARY CLOUD BOSWORTH

MONTANA STATE UNIVERSITY - BOZEMAN

Metabolomic Analysis as a Tool to Understanding the Use of Novel Therapeutics in

NGO, DEBBY

MASSACHUSETTS GENERAL HOSPITAL

The Kynurenine Pathway in Pulmonary Arterial Hypertension

PHELAN, VANESSA V

UNIVERSITY OF CALIFORNIA SAN DIEGO

The Interactive Metabolome of Polymicrobial Biofilms

ROWLEY, JESSE

UNIVERSITY OF UTAH

The Platelet Metabolome in Obesity

 

Regional Comprehensive Metabolomics Resource Cores (RCMRC) (U24) RFA-RM-11-016
PI Name Institution Name Title
BURANT, CHARLES F UNIVERSITY OF MICHIGAN AT ANN ARBOR Michigan Regional Comprehensive Metabolomics Resource Core (MRC2)
FIEHN, OLIVER UNIVERSITY OF CALIFORNIA DAVIS West Coast Central Comprehensive Metabolomics Resource Core (WC3MRC)
SUMNER, SUSAN J UNIVERSITY OF NORTH CAROLINA RTI's Regional Comprehensive Metabolomics Resource Center

 

 

This page last reviewed on January 6, 2017