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Funded Research

2023 NIH Director's Pioneer Award (DP1) (RFA-RM-22-018)

*Diversity Statement

PI NAMEINSTITUTION NAMETITLE
FORDYCE, POLLY MORRELLSTANFORD UNIVERSITYUsing microfluidics to realize patient-specific anti-cancer immunotherapies
GREENLEAF, WILLIAM JAMESSTANFORD UNIVERSITYCombinatorial Cell State Engineering
HOLFORD, MANDE NHUNTER COLLEGECharting the evolutionary development of novel genes and the molecular mechanisms of gland tissue organizationin cephalopods
JOHNSON, KEVIN BUNIVERSITY OF PENNSYLVANIAHelping Doctors Doctor: Using AI to Automate Documentation and "De-Autonomate" Health Care
QI, LEI STANLEYSTANFORD UNIVERSITYManipulating and Interrogating Spatial Transcriptomics
WANG, FAN MASSACHUSETTS INSTITUTE OF TECHNOLOGYUnraveling the Neural Bases of Body Schema
WITTEN, ILANA PRINCETON UNIVERSITYIndividual differences through self-reinforcement of suboptimal strategies
REIS, TANIA UNIVERSITY OF COLORADO DENVERFood for thought: a virus-like signal for the energetic demands of higher cognitive functions

 

2022 NIH Director's Pioneer Award (DP1) (RFA-RM-21-015)

*Diversity Statement

PI NameInstitution NameTitle
CAI, LONGCALIFORNIA INSTITUTE OF TECHNOLOGYSingle Cell Analysis of the Kinome
DZIRASA, KAFUIDUKE UNIVERSITYPrecision Editing of Neural Circuits Using Engineered Electrical Synapses
KRISHNAN, YAMUNAUNIVERSITY OF CHICAGOIntracellular Electrophysiology: An Electrochemical Atlas of Organelles
KWONG, GABRIEL AGEORGIA INSTITUTE OF TECHNOLOGYFinding Sleeping Beauty: T Cell Biosensors for Dormant Cancer Detection
NELSON, CELESTE MPRINCETON UNIVERSITYMechanical Clocks During Fetal Development
RANDLES, AMANDA EDUKE UNIVERSITYDynamic Models of the Cardiovascular System Capturing Years, Rather Than Heartbeats
ROSE, SHERRISTANFORD UNIVERSITYA Framework for the Social Impact of Algorithms in Health Care
SAWYER, SARAUNIVERSITY OF COLORADOBreaking the Barrier to an HIV Vaccine

 

2021 NIH Director's Pioneer Award (DP1) (RFA-RM-20-011)

*Diversity Statement

PI NameInstitution NameTitle
ANIKEEVA, POLINA OMASSACHUSETTS INSTITUTE OF TECHNOLOGYFusion of Nanomagnetic and Viral Tools to Interrogate Brain-Body Circuits
CLARK, PATRICIA LOUISEUNIVERSITY OF NOTRE DAMEDecoding the Regulation of Protein Folding by Synonymous Codon Usage
COSTA, RUI MCOLUMBIA UNIVERSITY HEALTH SCIENCESBrain Control of Internal Organ Function
GACK, MICHAELA ULRIKECLEVELAND CLINIC LERNER COM-CWRUDefining the Viral PTMome: Towards the Development of Novel Antiviral Approaches
HIGLEY, MICHAEL JAMESYALE UNIVERSITYBridging Cellular and Systems Neuroscience: Synaptic Dynamics Underlying Behavior
HUANG, Z JOSHDUKE UNIVERSITYRNA-Programmable Cell-Type Targeting, Editing, and Therapy
MURPHY, COLEEN TARAPRINCETON UNIVERSITYCracking the Code of Transgenerational Inheritance of Behavior
PHILLIPS-CREMINS, JENNIFER ELIZABETHUNIVERSITY OF PENNSYLVANIAFrom 3D Genomes to Neural Connectomes: Higher-Order Chromatin Mechanisms Encoding Long-Term Memory
RICHARDS, LINDA JWASHINGTON UNIVERSITYEmergence of Activity Patterns in the Cerebral Cortex and Their Influence on Brain Circuit Development and Function
SHAPIRO, MIKHAILCALIFORNIA INSTITUTE OF TECHNOLOGYSonogenetic Remote Control of Cellular Function

 

2020 NIH Director's Pioneer Award (DP1) (RFA-RM-19-005)

*Diversity Statement

PI NameInstitution NameTitle
BARRON, ANNELISE EMILYSTANFORD UNIVERSITYRole of Innate Immune Dysregulation in the Etiology of Dementia
COLLINS, KATHLEENUNIVERSITY OF CALIFORNIA BERKELEYHuman Genetic Supplementation Without Donor DNA or a DNA Break
HARVEY, CHRISTOPHER DHARVARD MEDICAL SCHOOLToward Mechanistic Cognitive Neuroscience: Cell Types, Connectivity, and Patterned Perturbations
KIM, PETER SSTANFORD UNIVERSITYCreating High-Resolution, Epitope-Focused Vaccines
LITT, BRIANUNIVERSITY OF PENNSYLVANIAGhost in the Machine: Melding Brain, Computer and Behavior
QIAN, SHU-BINGCORNELL UNIVERSITYA Genetic Circuit Formed by Ribosomes
ROSENBERG, SUSAN MBAYLOR COLLEGE OF MEDICINEHarnessing Proteins as Drugs: the Protectome of Cancer- and Aging-Prevention Proteins
SCHOGGINS, JOHN WUT SOUTHWESTERN MEDICAL CENTERA Functional Evolutionary Genetic Approach to Combat Viral Infection
VEESLER, DAVIDUNIVERSITY OF WASHINGTONUnraveling the Bat Humoral Immune Response Against Zoonotic Viruses to Guide the Design of Next-Generation Therapeutics
ZERNICKA-GOETZ, MAGDALENACALIFORNIA INSTITUTE OF TECHNOLOGYPlacental Models to Support Embryogenesis In Vitro

 

2019 NIH Director's Pioneer Award (DP1) (RFA-RM-18-007)

*Advisory Committee to the NIH Director Working Group Findings

PI NameInstitution NameTitle
ANDERMANN, MARK LBETH ISRAEL DEACONESS MEDICAL CENTERLook Inward: Brainstem and Cortical Circuits for Boosting Interoceptive Attention
EBERWINE, JAMES HUNIVERSITY OF PENNSYLVANIAThe Secret Lives of RNA: The In Vivo 3D-Structural Logic of Single Neuron RNA Metabolism
ELISSEEFF, JENNIFER HJOHNS HOPKINS UNIVERSITYBiomaterials-Directed Regenerative Immunotherapies
GRECO, VALENTINAYALE UNIVERSITYDefining the Role of Mutational Burden in Sustaining Normal Homeostasis During Aging
HERMAN, CHRISTOPHEBAYLOR COLLEGE OF MEDICINEA Synthetic Platform for Non-Antibiotic Eradication of Bacterial Infections
HUR, SUNBOSTON CHILDREN'S HOSPITALResolving Functional Aggregates: A New Perspective on Innate Immune Control
KNIGHT, ROBUNIVERSITY OF CALIFORNIA, SAN DIEGOMapping Host-Microbe-Metabolite Interactions in 3D to Find Diet-Derived Enhancers of Immunity
LEE, JIN HYUNGSTANFORD UNIVERSITYFrom Optogenetic Functional MRI to Mechanogenetic Functional Ultrasound
PICCIOTTO, MARINA RYALE UNIVERSITYAcetylcholine Signaling Allows Cognitive Processes in the Brain to Regulate Physiological Responses to the Environment: The Example of Central Control of Opiate Tolerance
PLOEGH, HIDDE LBOSTON CHILDREN'S HOSPITALImposing Order on the Family of Ubiquitin-Conjugating (E2) Enzymes Through Intracellular Perturbation with Nanobodies
SCHEURING, SIMONWEILL MEDICAL COLL OF CORNELL UNIVEnabling Physical Stimuli in the Study of Structural Dynamics: The Sensory Ion Channels

 

2018 NIH Director's Pioneer Award (DP1) (RFA-RM-17-005)

*Commitment to Diversity

PI NameInstitution NameTitle
AYRES, JANELLE SSALK INSTITUTE FOR BIOLOGICAL STUDIESHost-Microbe Interactions: Harnessing Co-Evolution to Treat Disease
COLON-RAMOS, DANIEL AYALE UNIVERSITYPowering the Brain: The Cell Biology of Neuroenergetics
CURTIS, CHRISTINA NSTANFORD UNIVERSITYForecasting Tumor Evolution: Can the Past Reveal the Future?
GRADINARU, VIVIANACALIFORNIA INSTITUTE OF TECHNOLOGYCircuit-Specific Delivery of Large Cargo Across the Nervous Systems of Adult Mammals and Embryos Via Novel Engineered Systemic Vectors
KIPNIS, JONATHANUNIVERSITY OF VIRGINIANeural Code of the Immune Responses
KWON, HYUNGBAEMAX PLANCK FLORIDA CORPORATIONCracking the Neuromodulation Code at Single Cell Resolution
MONJE-DEISSEROTH, MICHELLESTANFORD UNIVERSITYGlioma Circuitry: Bridging Systems Neuroscience and Cancer
VICTORA, GABRIEL DROCKEFELLER UNIVERSITYQuantifying Cell-Cell Interactions in the Immune System by Trans-Synaptic Labeling
WAGERS, AMY JOHARVARD UNIVERSITYUncovering Molecular Effectors of Mammalian Aging
YIN, PENGHARVARD UNIVERSITYHigh-Throughput Single-Molecule Protein Identification Via Super-Resolution Imaging

 

2017 NIH Director's Pioneer Award (DP1) (RFA-RM-16-005)

*Statement on Diversity

PI NameInstitution NameTitle
DAI, HONGJIESTANFORD UNIVERSITYHuman Infrared Vision at Molecular and Cellular Scale
ETKIN, AMITSTANFORD UNIVERSITYA “Circuits-First” Platform for Personalized Neurostimulation Treatment
FINE, HOWARD AWEILL MEDICAL COLL OF CORNELL UNIVHuman Brain Cancer, Rather than Brain Cancer Cells, on a Plate
LIEBER, CHARLES MHARVARD UNIVERSITYSyringe-Injectable Mesh Electronics for Seamless Integration with the Central Nervous System
MACKLIS, JEFFREY DHARVARD UNIVERSITYSubcellular RNA-Proteome Mapping in Subtype- and Circuit-Specific Growth Cones: Development, Cell Biology, Disease, and Regeneration
MARRAFFINI, LUCIANO AROCKEFELLER UNIVERSITYGeneration of Immunological Memory by CRISPR-Cas Systems
SCHIER, ALEXANDER FHARVARD UNIVERSITYDNA-Mediated Recording of Cellular History
SHIEKHATTAR, RAMINUNIVERSITY OF MIAMI SCHOOL OF MEDICINEEnhancer RNA Therapy
SINCLAIR, DAVID AHARVARD MEDICAL SCHOOLUncovering the Human Secretome
SONNENBURG, JUSTINSTANFORD UNIVERSITYDefining and Reconstructing the Human Ancestral Microbiome
TYE, KAY MAXINEMASSACHUSETTS INSTITUTE OF TECHNOLOGYNeural Circuit Mechanisms of Social Homeostasis in Individuals and Supraorganismal Social Groups
ZHANG, FENGBROAD INSTITUTE, INC.Exploration of Diverse Mobile Genetic Elements for Precision Genome Manipulation

 

2016 NIH Director's Pioneer Award (DP1) (RFA-RM-13-006)

PI NameInstitution NameTitle
BALDWIN, KRISTIN KAYSCRIPPS RESEARCH INSTITUTEDefining a Transcriptional Periodic Table of the Human Brain Using Reprogramming
BERNSTEIN, BRADLEY EVANMASSACHUSETTS GENERAL HOSPITALEpigenetic Plasticity in Tumor Initiation and Evolution
FISCHBACH, MICHAEL ANDREWUNIVERSITY OF CALIFORNIA, SAN FRANCISCOA Complete Map of the Top 100 Molecules from the Gut Microbiome
HASSON, URIPRINCETON UNIVERSITYSpeaker-Listener Coupling: A Novel Neural Approach for Assessing Communication
IZPISUA BELMONTE, JUAN CARLOSSALK INSTITUTE FOR BIOLOGICAL STUDIESGeneration of Functional Human Organs and Tissues Using Interspecific Blastocyst Complementation
KANWISHER, NANCYMASSACHUSETTS INSTITUTE OF TECHNOLOGYHow Does the Functional Organization of the Human Brain Arise in Development?
LIBERLES, STEPHEN DANIELHARVARD MEDICAL SCHOOLSensory Receptors of the Vagus Nerve
MAYR, CHRISTINESLOAN-KETTERING INST CAN RESEARCH3'UTR-Mediated Protein-Protein Interactions Determine Protein Functions
RABINOWITZ, JOSHUA DPRINCETON UNIVERSITYMetabolism in Action: Quantitative Fluxes in Mammals
WANG, MENG CARLABAYLOR COLLEGE OF MEDICINEDecode the Chemical Language that Orchestrates Cellular and Organismal Homeostasis
WAY, SING SINGCINCINNATI CHILDRENS HOSP MED CTRImmunological Identity Redefined by Genetically Foreign Microchimeric Cells
YUN, SEOK-HYUN ANDYMASSACHUSETTS GENERAL HOSPITALMassive Wavelength-Division Multiplexing and Imaging with Laser Particles

 

2015 NIH Director's Pioneer Award (DP1) (RFA-RM-13-006)

PI NameInstitution NameTitle
BOSCO, GIOVANNIDARTMOUTH COLLEGETrans-Generational Effects of Social Learning?
COX, JEFFERY SUNIVERSITY OF CALIFORNIA, SAN FRANCISCOHost-Directed Strategies to Create Synergistic Antibacterial Therapies
DISNEY, MATTHEW DSCRIPPS FLORIDAUsing a Disease-Affected Cell to Synthesize Its Own Drug
GITAI, ZEMERPRINCETON UNIVERSITYMechano-Microbiology: How Physical Forces Control Bacterial-Host Interactions
HOWARD, JONATHONYALE UNIVERSITYCell Biological Limitations Constrain Dendritic Branching Morphology and Neuronal Function
MONTELL, CRAIGUNIVERSITY OF CALIFORNIA SANTA BARBARACreation of a New Generation of Transgenic Mosquitoes to Control Infectious Disease
MURPHY, COLEEN TARAPRINCETON UNIVERSITYToward the Tissue-ome: A Map of the C. elegans Cell-specific Transcriptome
RANDOLPH, GWENDALYN JWASHINGTON UNIVERSITYIntegrating Cell & Lipoprotein Trafficking with Vascular Biology in Human IBD
SCHIFF, STEVEN JPENNSYLVANIA STATE UNIVERSITYControl of the Neonatal Septisome and Hydrocephalus in Sub-Saharan Africa
WU, HAOCHILDREN'S HOSPITAL CORPORATIONSMOCs: Novel Signal Transduction Complexes as New Targets for Drug Discovery
WYSS-CORAY, TONYPALO ALTO VETERANS INSTIT FOR RESEARCHA Bioorthogonal Approach to Study Mammalian Aging
YASUDA, RYOHEIMAX PLANCK FLORIDA CORPORATIONDeciphering Biochemical Networks in Single Dendritic Spines
ZHONG, SHENGUNIVERSITY OF CALIFORNIA SAN DIEGOMapping RNA interactomes by Sequencing

 

2014 NIH Director's Pioneer Award (DP1) (RFA-RM-13-006)

PI NameInstitution NameTitle
AMBATI, JAYAKRISHNAUNIVERSITY OF KENTUCKYForm and Function of Our Janus Faced Genome
GU, CHENGHUAHARVARD MEDICAL SCHOOLNew Tools for Understanding the Blood Brain Barrier
LAURENCIN, CATO T, MD, PHDUNIVERSITY OF CONNECTICUT HEALTH CENTERRegenerative Engineering of Complex Musculoskeletal Tissues and Joints
MONTELL, DENISE JUNIVERSITY OF CALIFORNIA SANTA BARBARAAnastasis, a New Mechanism Driving Cell Survival and Evolution
NOVINA, CARL DDANA-FARBER CANCER INSTITUTEEngineering Epigenetic Therapy for Sickle Cell Disease
PALMER, AMY EUNIVERSITY OF COLORADORegulation of Cell Signaling by Transition Metal Dynamics
PE'ER, DANACOLUMBIA UNIV NEW YORK MORNINGSIDESingle Cell Mapping of Developmental Trajectories Underlying Health and Disease
RANDO, OLIVER JUNIV OF MASSACHUSETTS MED SCH WORCESTERtRNA Fragments as Transgenerational Information Carriers
SPIEGELMAN, DONNA LHARVARD SCHOOL OF PUBLIC HEALTHComprehensive Translational Science Analytics Tools for the Global Health Agenda
WU, SEAN MSTANFORD UNIVERSITYEnabling Technologies for Human-Machine Hybrid Tissues

 

2013 NIH Director's Pioneer Award (DP1) (RFA-RM-12-015)

PI NameInstitution NameTitle
ARNSTEN, AMY F TYALE UNIVERSITYHighly Evolved Brain Circuits in Primates: Molecular Vulnerabilities for Disease
BOYDEN, EDWARD SMASSACHUSETTS INSTITUTE OF TECHNOLOGYMillisecond-Timescale Whole-Brain Neural Activity Mapping in Health and Disease
GLADYSHEV, VADIM NBRIGHAM AND WOMEN'S HOSPITALMechanisms of Lifespan Control
KHAKH, BALJITUNIVERSITY OF CALIFORNIA LOS ANGELESAstrocyte Branchlet Dysfunction as an Early Step in Brain Disorders

LIN, MICHAEL Z

 

STANFORD UNIVERSITYOptogenetics for All: A General Method for Optical Control of Protein Activity
SHENDURE, JAY ASHOKUNIVERSITY OF WASHINGTONInterpreting Genetic Variants of Uncertain Significance
TRAYANOVA, NATALIA AJOHNS HOPKINS UNIVERSITYVirtual Electrophysiology Laboratory
WANG, FANDUKE UNIVERSITYToward Causal Neuroscience: Capture and Manipulate Emergent Neuronal Ensembles
WEINBERGER, LEOR SJ. DAVID GLADSTONE INSTITUTESEvolvable Resistance-Proof Therapies
XIE, XIAOLIANG SUNNEYHARVARD UNIVERSITYProbing Dynamics of the Human Genome by Single Cell Sequencing
YUSTE, RAFAEL MCOLUMBIA UNIV NEW YORK MORNINGSIDEFunctional Connectomics of the Neocortical Microcircuit
ZYLKA, MARK JUNIV OF NORTH CAROLINA CHAPEL HILLThe Elongation Hypothesis of Autism

 

2012 NIH Director's Pioneer Award (DP1) (RFA-RM-11-004)

PI NameInstitution NameTitle
BRUNET, ANNESTANFORD UNIVERSITYTransgenerational Epigenetic Inheritance of Longevity
MARCOTTE, EDWARD MUNIVERSITY OF TEXAS AUSTINNext-Generation Proteomics: Massively Parallel Single-Molecule Protein Identification & Quantification
PLOEGH, HIDDE LWHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCHA New Strategy to Disrupt Protein-Protein Interactions in Eukaryotic Cells
SMOLKE, CHRISTINA DSTANFORD UNIVERSITYSynthetic Biology Platforms for Natural Product Discovery and Biosynthesis
TANG, YIUNIVERSITY OF CALIFORNIA LOS ANGELESRediscovering Natural Chemical Diversity
TSAO, DORIS YINGCALIFORNIA INSTITUTE OF TECHNOLOGYUnderstanding the Circuit for Topological Object Tracking
WANG, LIHONGWASHINGTON UNIVERSITY IN ST. LOUISPhoton Tunneling: Shedding New Light on Biomedicine
WU, CHAO-TINGHARVARD UNIVERSITYThe Inheritance of Position: It's Not Just Who You Are, It's Where You Are
YELLEN, GARY IHARVARD UNIVERSITYSingle Cell Analysis of Metabolism Using Genetically-Encoded Fluorescent Sensors
ZHANG, FENGBROAD INSTITUTE, INC.Probing Neuropsychiatric Diseases Using Targeted Epigenome and Genome Engineering

 

2011 NIH Director's Pioneer Award (DP1) (RFA-RM-10-008)

PI NameInstitution NameTitle
BANERJEE, UTPALUNIVERSITY OF CALIFORNIA LOS ANGELESDevelopmental Control of Metabolism
BASS, BRENDA LUNIVERSITY OF UTAHCellular Double-Stranded RNA as a Signal of Stress, Immunity, and Aging
BENNETT, JEANUNIVERSITY OF PENNSYLVANIABroad Spectrum Molecular Therapy for Blinding Retina Disorders
CLEMONS, WILLIAM MCALIFORNIA INSTITUTE OF TECHNOLOGYNIH Pioneer Award
ENGERT, FLORIANHARVARD UNIVERSITYWatching a Vertebrate Brain Learn and Behave in a Virtual Environment
FEINBERG, ANDREW PJOHNS HOPKINS UNIVERSITYA General Stochastic Epigenetic Model for Evolution, Development, and Disease
HILDRETH, JAMES E KMEHARRY MEDICAL COLLEGERole of Natural Pseudotyping with Other Viruses in HIV Transmission
PAN, TAOUNIVERSITY OF CHICAGOMis-Translation as a New Mechanism of Stress Response in Biology
RAMANATHAN, SHARADHARVARD UNIVERSITYA Road Map to the Neocortex
SCHNEIDER, DAVID SSTANFORD UNIVERSITYMapping the Road to Recovery - Does the Way We Get Better Differ from the Way We Get Sick?
SIAPAS, ATHANASSIOS GCALIFORNIA INSTITUTE OF TECHNOLOGYNanoprobe Arrays for Massively Parallel 3-D Recordings of Brain Activity
TOLIAS, ANDREAS SAVASBAYLOR COLLEGE OF MEDICINEDissecting the Fabric of the Cerebral Cortex
YANIK, MEHMET FATIHMASSACHUSETTS INSTITUTE OF TECHNOLOGYGenerating Transplantable Neurons by In Vivo Combinatorial Screening of Transcription Regulator RNAs

 

2010 NIH Director's Pioneer Award (DP1) (RFA-RM-09-010)

PI NameInstitution NameTitle
BARBAS, CARLOS FSCRIPPS RESEARCH INSTITUTEChemically Programmed Immunity
BJORKMAN, PAMELA JCALIFORNIA INSTITUTE OF TECHNOLOGYThwarting HIV Evasion of Antibody Avidity with Novel Antibody Architectures
DRAGOI, VALENTINUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTONExamining Population Coding Underlying Complex Behavior in Freely Moving Primates
FESIK, STEPHEN WVANDERBILT UNIVERSITY MEDICAL CENTERExpanding the Druggable Genome
HORVATH, TAMAS LYALE UNIVERSITYHypothalamic AgRP Neurons Are Determinants of Healthy Lifespan and Higher Brain Functions
JOUNG, J KEITHMASSACHUSETTS GENERAL HOSPITALAdvancing Stem Cell Technologies Using Engineered Zinc Finger Proteins
KLEINFELD, DAVIDUNIVERSITY OF CALIFORNIA SAN DIEGODefining the Logic of Neurovascular Signaling in the Brain
LIN, HAIFANYALE UNIVERSITYToward a Central Question in Epigenetics: A Major Epigenetic Programming Mechanism Guided by piRNAs
LIU, JUN OJOHNS HOPKINS UNIVERSITYGeneration and Proteome-Wide Screening of Hybrid Combinatorial Libraries
MARICQ, ANDRES VILLUUNIVERSITY OF UTAHSimultaneous In Vivo Studies of Synapses, Neurons, and Learning and Memory
NADEAU, JOSEPH HCASE WESTERN RESERVE UNIVERSITYLamarck Redux: Transgenerational Genetic Effects on Phenotypes and Disease
NICOLELIS, MIGUEL A LDUKE UNIVERSITYA Virtual Reality Simulator to Study VLSBA and Test Brain-Actuating Technologies
RAMAKRISHNAN, LALITAUNIVERSITY OF WASHINGTONLinking the Behavior of Individual Host Cells to Their Transcriptional Signatures
ROLE, LORNA WTHE RESEARCH FOUNDATION OF SUNYUnveiling the Role and Taking Control of Cholinergic Tone in Circuits of Attention, Memory and Fear
ROUKES, MICHAEL LCALIFORNIA INSTITUTE OF TECHNOLOGYNanoscale Tools to Push Biomedical Frontiers
SAMUDRALA, RAMUNIVERSITY OF WASHINGTONNovel Paradigms for Drug Discovery: Computational Multitarget Screening
YANKNER, BRUCE APRESIDENT AND FELLOWS OF HARVARD COLLEGEModeling the Aging Epigenome

 

2009 NIH Director's Pioneer Award (DP1) (RFA-RM-09-001)

PI NameInstitution NameTitle
BENJAMIN, IVOR JUNIVERSITY OF UTAHProtein Misfolding Diseases and Oxido-Reductive Pathways
CHAWLA, AJAYSTANFORD UNIVERSITYImmune Triggers of Tissue Regeneration
CHEN, CHANG-ZHENGSTANFORD UNIVERSITYThe Role of Pre-miRNA Loop in Target Regulation by microRNA Genes
CHEROUTRE, HILDE MCLA JOLLA INST FOR ALLERGY & IMMUNOLGYUncovering the Missing Link that Determines Susceptibility to Autoimmunity
COVERT, MARKUS WSTANFORD UNIVERSITYA Gene-Complete Computational Model of Yeast
DESIMONE, JOSEPH MUNIV OF NORTH CAROLINA CHAPEL HILLDelivery of Biological Therapeutics: Using Engineered Particles and Novel Delivery Methods to Address Unmet Needs
EVANS, SYLVIA MUNIVERSITY OF CALIFORNIA SAN DIEGOApproaches to Cardiac Regeneration
FETCHO, JOSEPH RCORNELL UNIVERSITYGlobal Changes in Synaptic Strength and Excitability During Sleep and Wakefulness
HOLY, TIMOTHYWASHINGTON UNIVERSITYWatching Action Potentials in Intact Neuronal Circuits
REYA, TANNISHTHADUKE UNIVERSITYImaging Self-Renewal and Transformation in Hematopoietic Stem Cells
ROBINSON, GENE EUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGNJohnny Bee Good: Bees as Models to Study the Hijacking of the Reward System
ROSENBERG, SUSAN MBAYLOR COLLEGE OF MEDICINEForward Genomics of Damage Control: An Undiscovered Class of Cancer Genes
SAMSON, LEONA DMASSACHUSETTS INSTITUTE OF TECHNOLOGYDeveloping Novel Methods to Measure DNA Repair Capacity in Human Populations
SHAH, NIRAO MAHESHUNIVERSITY OF CALIFORNIA, SAN FRANCISCODissecting the Neural Control of Social Attachment
SHENOY, KRISHNA VSTANFORD UNIVERSITYToward an Animal Model of Freely Moving Human
TISHKOFF, SARAH ANNEUNIVERSITY OF PENNSYLVANIAAfrican Odyssey: An Integrative Genomics Analysis of Complex Physiologic Traits
TRAVIS, ALEXANDER JCORNELL UNIVERSITYNanoscale Energy Production for Implantable Medical Devices
ZHANG, JINJOHNS HOPKINS UNIVERSITYCreating a Genetically Encodable Nano-Compass to Navigate in Molecular Networks

 

2008 NIH Director's Pioneer Award (DP1) (RFA-RM-08-013)

PI NameInstitution NameTitle
CHEN, JAMES KSTANFORD UNIVERSITYChemical Embryology: Technologies for Manipulating and Visualizing Development
DOLMETSCH, RICARDO ESTANFORD UNIVERSITYUsing Induced Pluripotent Stem Cells to Identify Cellular Phenotypes of Autism
EBERWINE, JAMES HUNIVERSITY OF PENNSYLVANIACellular Logic of Phenotype
EPSTEIN, JOSHUA MBROOKINGS INSTITUTIONBehavioral Epidemiology: Applications of Agent-Based Modeling to Infectious Disease
HAY, BRUCE ACALIFORNIA INSTITUTE OF TECHNOLOGYEngineering the Genetics of Wild Mosquito Populations to Fight Infectious Disease
HOCHSCHILD, ANNHARVARD MEDICAL SCHOOLA New Genetic Approach for Studying Prions and Other Pathogenic Protein Aggregate
LIEBER, CHARLES MHARVARD UNIVERSITYNanowire Nanoelectronic/Cell Assemblies as Hybrid Functional Biomaterials
LONDON, BARRYUNIVERSITY OF PITTSBURGH AT PITTSBURGHIn-Vivo Electrophysiology Imaging
MANIATIS, THOMAS PHARVARD UNIVERSITYUse of Induced Pluripotent Stem Cells to Study Mechanims of Familial and Sporadic ALS
ODOM, TERI WANGNORTHWESTERN UNIVERSITYReconstructing Sub-cellular Structure Using Plasmonic Metamaterials
PARK, HONGKUNHARVARD UNIVERSITYNano- and Microelectronic Tools for Interrogating Neuronal Circuits and Networks
REGEV, AVIVMASSACHUSETTS INSTITUTE OF TECHNOLOGY | BROAD INSTITUTE, INC.The Temporal Reconfiguration of Regulatory Networks: From Yeast to Cancer
SAMUEL, ARAVINTHAN DHARVARD UNIVERSITYBiophysical Approaches to Complex Navigational Behaviors in Larval Drosophila melanogaster
TAVAZOIE, SAEED FPRINCETON UNIVERSITYTowards a Cognitive Framework for Understanding Cellular Behavior
TING, ALICE YMASSACHUSETTS INSTITUTE OF TECHNOLOGYEnabling the Study of Endogenous Proteins in Live Cells
VAN OUDENAARDEN, ALEXANDERMASSACHUSETTS INSTITUTE OF TECHNOLOGYStochastic Gene Expression in Differentiation and Development

 

2007 NIH Director's Pioneer Award (DP1) (RFA-RM-07-005)

PI NameInstitution NameTitle
BARRETT, LISA FELDMANBOSTON COLLEGEEmotions Are Emergent Events Constrained by Affective and Conceptual Processes
BEARMAN, PETER SHAWNCOLUMBIA UNIV NEW YORK MORNINGSIDESocial Determinants of the Autism Epidemic
BROWN, EMERY NMASSACHUSETTS GENERAL HOSPITALA Systems Neuroscience Approach for the Study of General Anesthesia
CLANDININ, THOMAS ROBERTSTANFORD UNIVERSITYDissecting the Functional Anatomy of the Visual System: A New Way Forward
COLLINS, JAMES JBOSTON UNIVERSITY (CHARLES RIVER CAMPUS)A Network Biology Approach to Antibiotic Action and Bacterial Defense Mechanisms
GARDEL, MARGARET LISEUNIVERSITY OF CHICAGO2007 NIH Directors Pioneer Award Program (DP1)
HENSCH, TAKAO KCHILDREN'S HOSPITAL CORPORATIONDissecting Non-Coding RNA Function in Critical Period Brain Development/ Disorder
HORWITZ, MARSHALL SUNIVERSITY OF WASHINGTONNIH Directors Pioneer Award
ISMAGILOV, RUSTEM FUNIVERSITY OF CHICAGO2007 NIH Directors Pioneer Award Program (DP1)
JENSEN, FRANCES ECHILDREN'S HOSPITAL CORPORATIONUnderstanding the Cognitive Impact of Early Life Epilepsy
SCHNITZER, MARK JSTANFORD UNIVERSITYMassively Parallel Brain Imaging
TURRIGIANO, GINA GBRANDEIS UNIVERSITYProbing the Structure of the Synapse Using Superresolution Light Microscopy

 

2006 NIH Director's Pioneer Award (DP1) (RFA-RM-06-005)

PI NameInstitution NameTitle
BOAHEN, KWABENASTANFORD UNIVERSITYNeurogrid: Emulating a Million Neurons in the Cortex
CHAKRABORTY, ARUP KMASSACHUSETTS INSTITUTE OF TECHNOLOGYDeveloping the Principles Governing T Lymphocyte-Mediated Autoimmunity Using an Approach at an Intersection of the Physical and Life Sciences
GIERASCH, LILA MUNIVERSITY OF MASSACHUSETTS AMHERSTNIH Director's Pioneer Award Application
HEALD, REBECCA WUNIVERSITY OF CALIFORNIA BERKELEYNIH Director's Pioneer Award Application
KIRKEGAARD, KARLA ASTANFORD UNIVERSITYDominant Drug Targets in RNA Viruses
KODADEK, THOMASUNIVERSITY OF TEXAS SW MED CTR/DALLASNovel Chemistry to Monitor and Manipulate the Immune System
LEE, CHENG CUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTONReversible Suspended Animation of Non-hibernating Mammals
NUDLER, EVGENYNEW YORK UNIVERSITY SCHOOL OF MEDICINENew Approaches to Fight Infection
PIELAK, GARY JUNIVERSITY OF NORTH CAROLINA CHAPEL HILLIn-Cell NMR of Disease-Related Proteins
RELMAN, DAVID ASTANFORD UNIVERSITYNIH Director's Pioneer Award Application
SEGAL, ROSALIND ADANA-FARBER CANCER INSTITUTEAn Extended View of Self: Human Indigenous Microbial Communities in Health and Disease
SHERLEY, JAMES LMASSACHUSETTS INSTITUTE OF TECHNOLOGYPioneering Human Adult Stem Cell Discovery and Cellular Medicine
XIA, YOUNANUNIVERSITY OF WASHINGTONPut Nanostructures to Work for Reading and Controlling Cell Behavior

 

2005 NIH Director's Pioneer Award (DP1) (NOT-OD-05-021)

PI NameInstitution NameTitle
CHANDLER, VICKI LUNIVERSITY OF ARIZONANIH Director's Pioneer Award
CLINE, HOLLIS TCOLD SPRING HARBOR LABORATORYNIH Director's Pioneer Award
COSMIDES, LEDAUNIVERSITY OF CALIFORNIA SANTA BARBARANIH Director's Pioneer Award
DE LANGE, TITIAROCKEFELLER UNIVERSITYNIH Director's Pioneer Award
DEISSEROTH, KARL ASTANFORD UNIVERSITYNIH Director's Pioneer Award
HARBURY, PEHR ASTANFORD UNIVERSITY SCHOOL OF MEDICINENIH Director's Pioneer Award
JARVIS, ERICH DDUKE UNIVERSITY MEDICAL CENTERNIH Director's Pioneer Award
RANDO, THOMAS ASTANFORD UNIVERSITY SCHOOL OF MEDICINENIH Director's Pioneer Award
SMITH, DEREK JUNIVERSITY OF CAMBRIDGENIH Director's Pioneer Award
TONONI, GIULIOUNIVERSITY OF WISCONSIN - MADISON MEDICAL SCHOOLNIH Director's Pioneer Award
WATERMAN-STORER, CLARE MSCRIPPS RESEARCH INSTITUTENIH Director's Pioneer Award
WOLFE, NATHANJOHNS HOPKINS UNIVERSITYNIH Director's Pioneer Award
YUAN, JUNYINGHARVARD MEDICAL SCHOOLNIH Director's Pioneer Award

 

2004 NIH Director's Pioneer Award (DP1) (RFA-RM-04-500)

PI NameInstitution NameTitle
ABBOTT, LARRY FBRANDEIS UNIVERSITYNIH Director's Pioneer Award
DALEY, GEORGE QCHILDREN'S HOSPITAL (BOSTON)NIH Director's Pioneer Award
HELLINGA, HOMME WDUKE UNIVERSITYNIH Director's Pioneer Award
MCCUNE, JOSEPH MJ. DAVID GLADSTONE INSTITUTESNIH Director's Pioneer Award
MCKNIGHT, STEVEN LUNIVERSITY OF TEXAS SW MED CTR/DALLASNIH Director's Pioneer Award
MIRKIN, CHAD ANORTHWESTERN UNIVERSITYNIH Director's Pioneer Award
PHILLIPS, ROBCALIFORNIA INSTITUTE OF TECHNOLOGYNIH Director's Pioneer Award
QUAKE, STEPHEN RCALIFORNIA INSTITUTE OF TECHNOLOGYNIH Director's Pioneer Award
XIE, SUNNEYHARVARD UNIVERSITYNIH Director's Pioneer Award
 

This page last reviewed on February 5, 2024