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Computational Analyses Exploiting Reference Epigenomic Maps (R01) RFA-RM-14-001
PI Name Institution Name Title
FUREY, TERRENCE S. (contact)
SHEIKH, SHEHZAD Z.
UNIV OF NORTH CAROLINA CHAPEL HILL Interpreting molecular role of DNA variants associated with Crohns Disease through integrative analysis of open chromatin, epigenome and transcriptome data in diverse and relevant tissues and cells
INCE, TAN A. UNIVERSITY OF MIAMI Computational and Biological Deconvolution of Epigenomic Datasets
JOHNSON, WILLIAM EVAN BOSTON UNIVERSITY MEDICAL CAMPUS Integrative analyses of reference epigenomic maps and applications
LI, ZHAOYU (contact)
ASMANN, YAN W.
MAYO CLINIC  JACKSONVILLE Building the Foundation of Epigenomics Roadmaps
LIU, CHUNYU UNIVERSITY OF ILLINOIS AT CHICAGO Integrating epigenomic maps to predict regulatory functions of genetic variants
NOBLE, WILLIAM STAFFORD UNIVERSITY OF WASHINGTON Machine learning methods to impute and annotate epigenomic maps
PRITCHARD, JONATHAN K STANFORD UNIVERSITY Computational methods for modeling lineage-specific gene regulation
REN, BING LUDWIG INSTITUTE  FOR CANCER RES  LTD Integrative Analysis of Haplotype-Resolved Human Epigenome Maps
WAGERS, AMY JO HARVARD UNIVERSITY Epigenomic drivers of human muscle progenitor cells in development and disease
WANG, TING WASHINGTON UNIVERSITY CHARTING THE EPIGENOMIC LANDSCAPE OF HUMAN TRANSPOSABLE ELEMENTS
XING, YI (contact)
HOFFMANN, ALEXANDER
UNIVERSITY OF CALIFORNIA LOS ANGELES Epigenomic control of RNA splicing
 
Functional Epigenomics: Developing Tools and Technologies for Cell-type, Temporal, or Locus-specific Manipulation of the Epigenome
(R01) RFA-RM-12-026
PI Name Institution Name Title
BLANCAFORT, PILAR (contact)
LISTER, RYAN
UNIVERSITY OF WESTERN AUSTRALIA Precision engineering of DNA methylation patterns in the human genome
DURONIO, ROBERT J (contact)
MATERA, A. GREGORY
STRAHL, BRIAN D
UNIV OF NORTH CAROLINA CHAPEL HILL Engineering histone genes to interrogate the epigenetic code in space and time
GERSBACH, CHARLES A (contact)
CRAWFORD, GREGORY E
DUKE UNIVERSITY Engineering Targeted Epigenetic Modifiers for Precise Control of Gene Regulation
KOIDE, SHOHEI UNIVERSITY OF CHICAGO Genetically encoded designer inhibitors for functional epigenomics
KUHLMAN, BRIAN A (contact)
HAHN, KLAUS MICHAEL
UNIV OF NORTH CAROLINA CHAPEL HILL Spatiotemporal Control of the Epigenome via Photoactivatable Nuclear Localization
LEE, JEANNIE T MASSACHUSETTS GENERAL HOSP The RNA-activation platform to treat X-linked disease in a locus-specific manner
LOMVARDAS, STAVROS (contact)
BARNEA, GILAD
UNIVERSITY OF CALIFORNIA SAN FRANCISCO Controlling epigenetic states and nuclear architecture in the brain
MEISSNER, ALEXANDER HARVARD UNIVERSITY Generation and characterization of tools for target-specific de novo DNA methylat
TASIC, BOSILJKA (contact)
MADISEN, LINDA
ALLEN INSTITUTE FOR BRAIN SCIENCE Temporal, cell type- and locus-specific epigenetic control in transgenic mice
WEISSMAN, JONATHAN S. (contact)
LIM, WENDELL A
QI, LEI STANLEY
UNIVERSITY OF CALIFORNIA SAN FRANCISCO Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming
 
Epigenomics of Human Health and Disease (R01)
RFA-RM-08-017
PI Name Institution Name Title
BENNETT, DAVID A. RUSH UNIVERSITY MEDICAL CENTER Exploring the Role of the Brain Epigenome: Cognitive Decline and Life Experiences
COLEMAN, PAUL D. SUN HEALTH RESEARCH INSTITUTE DNA methylation in Alzheimer's disease and normally aged brain
CONNELLY, JESSICA J. UNIVERSITY OF VIRGINIA CHARLOTTESVILLE Epigenomics of Atherosclerosis
EINSTEIN, FRANCINE HUGHES (contact)
GREALLY, JOHN
MONTAGNA, CRISTINA
YESHIVA UNIVERSITY Genome-wide DNA Methylation Profiles Associated with Abnormal Intrauterine Growth
FALLIN, MARGARET DANIELE (Contact)
FEINBERG, ANDREW P.
JOHNS HOPKINS UNIVERSITY Environment, The Perinatal Epigenome, and Risk for Autism and Related Disorders
GIBBONS, GARY HUGH MOREHOUSE SCHOOL OF MEDICINE Vascular Epigenome Dynamics in African-American Hypertensives
HUANG, TIM H.-M. OHIO STATE UNIVERSITY Epigenomics of Bisphenol A Exposure and Disease Risk
KOHWI-SHIGEMATSU, TERUMI UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB Determinants for genome-wide epigenomics in metastatic breast cancer
LIU, YONGMEI WAKE FOREST UNIVERSITY HEALTH SCIENCES Epigenome-Wide Association Study of DNA Methylation and Atherosclerosis
MELTZER, STEPHEN J. JOHNS HOPKINS UNIVERSITY The temporal epigenomic program of Barrett's neoplastic progression
MERBS, SHANNATH L. JOHNS HOPKINS UNIVERSITY Pangenomic Analysis of DNA Methylation Marks in Glaucoma and Macular Degeneration
MILL, JONATHAN KING'S COLLEGE LONDON A multi-faceted approach to epigenomic profiling in Alzheimer's disorder
OPHOFF, ROEL A. UNIVERSITY OF CALIFORNIA LOS ANGELES Epigenetics and disease: the role of DNA methylation in schizophrenia susceptibility
PETRONIS, ART CENTRE FOR ADDICTION AND MENTAL HEALTH DNA METHYLOME ANALYSIS IN BIPOLAR DISORDER
PFEIFER, GERD P. CITY OF HOPE/BECKMAN RESEARCH INSTITUTE Aging and the unstable epigenome
ROSEN, EVAN D. BETH ISRAEL DEACONESS MEDICAL CENTER Epigenomics of Human Insulin Resistance
SCHWARTZ, DAVID ALBERT (contact)
COSGROVE, GREGORY P.
YANG, IVANA VERONA
NATIONAL JEWISH HEALTH Asthma: An Epidemic Caused by Epigenetics?
SULLIVAN, KATHLEEN E. CHILDREN'S HOSPITAL OF PHILADELPHIA Epigenomics of SLE
SUSZTAK, KATALIN (contact)
GREALLY, JOHN
YESHIVA UNIVERSITY Epigenetics Landscape of Chronic Kidney Disease
TYCKO, BENJAMIN (contact)
MAYEUX, RICHARD
COLUMBIA UNIVERSITY HEALTH SCIENCES Epigenomics of Alzheimer's Disease
YOKOMORI, KYOKO UNIVERSITY OF CALIFORNIA IRVINE Epigenomic Analysis of Facioscapulohumeral Muscular Dystrophy
YOUNG, RICHARD WHITEHEAD INSTITUTE FOR BIOMEDICAL RES Epigenomic Mapping in Human Tumor Stem Cells

 

Reference Epigenome Mapping Centers (U01)
RFA-RM-07-013
PI Name Institution Name Title
BERNSTEIN, BRADLEY E (contact)
MEISSNER, ALEXANDER
MASSACHUSETTS INSTITUTE OF TECHNOLOGY Production sequencing of reference human epigenomes
COSTELLO, JOSEPH F (contact)
MARRA, MARCO ANTONIO
UNIVERSITY OF CALIFORNIA SAN FRANCISCO Integrated Epigenetic Maps of Human Embryonic and Adult Cells
REN, BING LUDWIG INSTITUTE FOR CANCER RESEARCH The San Diego Epigenome Center
STAMATOYANNOPOULOS, JOHN UNIVERSITY OF WASHINGTON Northwest Reference Epigenome Mapping Center

 

Epigenomics Data Analysis and Coordination Center - EDACC (U01)
RFA-RM-07-014
PI Name Institution Name Title
BEAUDET, ARTHUR L.
MILOSAVLJEVIC, ALEKSANDAR (contact)
BAYLOR COLLEGE OF MEDICINE Epigenomics Data Analysis and Coordination Center at Baylor College of Medicine

 

Developing Technologies for Improved In Vivo Epigenetic Imaging or Analysis (R01)
RFA-RM-09-016
PI Name Institution Name Title
GELOVANI, JURI G UNIVERSITY OF TEXAS MD ANDERSON CAN CTR Novel HDAC Class III Specific Radiotracers for PET Imaging
GREALLY, JOHN (contact) LEVY, MATTHEW ALBERT EINSTEIN COL OF MED YESHIVA UNIV In vivo imaging of X inactivation
HENIKOFF, STEVEN FRED HUTCHINSON CANCER RESEARCH CENTER Epigenomic profiling of histone turnover kinetics in mammalian cells
HOOKER, JACOB M MASSACHUSETTS GENERAL HOSPITAL Design of Class-specific HDAC Imaging Probes for Positron Emission Tomography
KERPPOLA, TOM UNIVERSITY OF MICHIGAN AT ANN ARBOR Visualization of Combinatorial Epigenetic Marks and Complexes in Animals Using Fl
LAIRD, PETER W UNIVERSITY OF SOUTHERN CALIFORNIA Visualizing the effect of epigenetic modifications on transcription and mutation
LIS, JOHN THOMAS (contact) CRAIGHEAD, HAROLD G LIN, HENING ZIPFEL, WARREN R CORNELL UNIVERSITY ITHACA In vivo Detection and Imaging of Epigenetic Histone Modifications and Modifying E
LOMVARDAS, STAVROS (contact) LARABELL, CAROLYN A UNIVERSITY OF CALIFORNIA SAN FRANCISCO Devising New Technologies for Live Imaging of Epigenetic Processes
YOUNG, WON-BIN (contact) AHRENS, ERIC T CARNEGIE-MELLON UNIVERSITY In Vivo Visualization and Quantification of Epigenetic Activities Using Magnetic

 

Technology Development in Epigenetics (R21)
RFA-RM-07-012
PI Name Institution Name Title
BEDFORD, MARK T GOZANI, OR P (contact) STANFORD UNIVERSITY Applying peptide and protein domain microarrays to epigenetic research
HANG, HOWARD C ROCKEFELLER UNIVERSITY Chemical Reporters for the Analysis of Lysine Methylation in Epigenetics
HENIKOFF, STEVEN FRED HUTCHINSON CANCER RESEARCH CENTER Genome-wide measurement of histone replacement rates: a new dimension in epigenom
KOIDE, SHOHEI UNIVERSITY OF CHICAGO Novel affinity reagents for epigenetics markers
LIU, RIHE UNIVERSITY OF NORTH CAROLINA CHAPEL HILL Identification of the Interactome of Methylated Histones from Human Proteome

 

Technology Development in Epigenetics (R01
RFA-RM-07-011
PI Name Institution Name Title
CRAIGHEAD, HAROLD G SOLOWAY, PAUL D (contact) CORNELL UNIVERSITY ITHACA Epigenomic analysis on a nanoscale device
MITRA, ROBI D WASHINGTON UNIVERSITY METHYLMAP: A TECHNOLOGY TO ANALYZE PROMOTER METHYLATION IN MICRODISSECTED CELLS
SHI, HUIDONG ZHANG, KUN (contact) UNIVERSITY OF CALIFORNIA SAN DIEGO Genome-scale anaylsis of DNA methylation in CpG Islands with bisulfite sequencing
TACKETT, ALAN JACKSON (contact) TAVERNA, SEAN D UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK Development of technology for high resolution epigenetic profiling of chromatin

 

Discovery of Novel Epigenetic Marks in Mammalian Cells (R21)
RFA-RM-07-016
PI Name Institution Name Title
CHEN, XIAN STRAHL, BRIAN D (contact) UNIVERSITY OF NORTH CAROLINA CHAPEL HILL Identification of novel histone modifications in a model eukaryote
WARBURTON, PETER E MOUNT SINAI SCHOOL OF MEDICINE OF NYU Non-coding RNAs in the epigenetics of human centromere formation

 

Discovery of Novel Epigenetic Marks in Mammalian Cells (R01)
RFA-RM-07-015
PI Name Institution Name Title
CHENG, XIAODONG EMORY UNIVERSITY Identification and characterization of novel epigenetic marks of non-histone prot
GRANT, PATRICK A UNIVERSITY OF VIRGINIA CHARLOTTESVILLE Characterization of a novel histone H3 phosphorylation mark in DNA replication
KATZ, RICHARD ALAN INSTITUTE FOR CANCER RESEARCH Discovery of Epigenetic Marks in Human Cells by High Throughput siRNA Screening
OETTINGER, MARJORIE A MASSACHUSETTS GENERAL HOSPITAL Is symmetrical dimethylation of Arginine 2 of Histone H3 used as an epigenetic si
TULIN, ALEXEI V ZARET, KENNETH S (contact) INSTITUTE FOR CANCER RESEARCH Novel Epigenetic Marks in Mitosis
ZHAO, YINGMING UNIVERSITY OF TEXAS SW MED CTR/DALLAS Systematic screening for new histone marks
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