The Common Fund's Epigenomics Program includes a series of complementary initiatives aimed at generating new research tools, technologies, datasets, and infrastructure to accelerate our understanding of how genome-wide chemical modifications to DNA regulate gene activity without altering the DNA sequence itself and what role these modifications play in health and disease.
A Scientific Illustration of How Epigenetic Mechanisms Can Affect Health
Epigenomes Around the WorldThe Epigenomics Program is part of the International Human Epigenome Consortium that aims to coordinate worldwide epigenome mapping and characterization efforts.
Tips and Tools for Using Epigenomics Resources
NEW! ENCODE/Roadmap Epigenomics Tutorial
NEW! A Guide to the Epigenome
NEW! Epigenomics: The New Technologies of Chromatin Analysis
Overview of Epigenomics program resources
NEW! Epigenomics researchers publish new study linking genetic variation and gene regulation in many common diseases
Dr. John Stamatoyannopoulos and colleagues, supported in part by the Common Fund’s Epigenomics program, have discovered that genetic differences linked to a wide variety of diseases influence how genes are turned on, or expressed. These results provide new insight into disease mechanisms, and suggest novel targets for therapeutics development and disease prevention strategies for a wide variety of common diseases.