The NIH Director's Early Independence Award supports exceptional early career scientists with the intellect, scientific creativity, drive, and maturity to flourish independently by bypassing the traditional post-doctoral training period.
Silencing the X Chromosome
How long non-coding RNA (lncRNAs) work to control gene regulation is largely unknown due to technical limitations in viewing lncRNAs in the cell. Dr. Guttman, a 2012 awardee, published a paper in Nature describing a new approach to viewing lncRNA complexes in cells, allowing researchers to decipher how they are involved in gene regulation. Using this approach, Guttman deciphered the mechanisms of X chromosome silencing during female development.
Can the Intellectual Disability Caused by Kabuki Syndrome be Reversed?
Dr. Hans Tomas Bjornsson, a 2013 awardee, published a paper in Science Translational Medicine, showing a deficiency of dentate gyrus neurogenesis may underlie some of the neurological dysfunction seen in a mouse model of Kabuki syndrome, a rare Mendelian cause of intellectual disability.
Yakeel Quiroz Featured in NIH Director's Blog
Save the date for the 2015 High-Risk, High-Reward Research Symposium on December 7-9 at Natcher Conference Center, NIH, Bethesda, MD!